# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Methuselah_N PF06652.12 KIY42797.1 - 0.003 17.5 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Methuselah N-terminus zf-HC2 PF13490.6 KIY42797.1 - 0.049 13.9 0.4 0.13 12.5 0.4 1.7 1 0 0 1 1 1 0 Putative zinc-finger SKN1 PF03935.15 KIY42798.1 - 6.9e-173 575.6 11.8 1.7e-171 571.1 11.8 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Cpn60_TCP1 PF00118.24 KIY42799.1 - 0.00067 18.4 0.6 0.18 10.4 0.1 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family TFIIE_beta PF02186.15 KIY42799.1 - 0.066 13.5 0.0 0.091 13.1 0.0 1.2 1 0 0 1 1 1 0 TFIIE beta subunit core domain Pkinase_fungal PF17667.1 KIY42800.1 - 1e-06 27.8 0.1 1.5e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase adh_short_C2 PF13561.6 KIY42801.1 - 5.2e-14 52.4 0.0 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY42801.1 - 0.025 14.0 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase F-box-like PF12937.7 KIY42802.1 - 0.0029 17.4 0.1 0.0073 16.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like Bromo_TP PF07524.13 KIY42804.1 - 0.032 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated SlyX PF04102.12 KIY42806.1 - 0.034 14.7 0.7 0.17 12.5 0.3 2.3 2 0 0 2 2 2 0 SlyX PSRT PF07636.11 KIY42806.1 - 0.39 10.4 7.4 0.83 9.4 7.4 1.5 1 0 0 1 1 1 0 PSRT CxC2 PF18803.1 KIY42807.1 - 9.2e-15 54.7 0.4 1.5e-14 54.1 0.4 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY42807.1 - 0.0029 17.7 0.1 0.0052 16.9 0.1 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Agenet PF05641.12 KIY42808.1 - 0.11 13.0 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Agenet domain Y_phosphatase3 PF13350.6 KIY42813.1 - 0.0021 18.1 0.1 0.005 16.9 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KIY42813.1 - 0.0021 18.2 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KIY42813.1 - 0.0043 16.7 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KIY42813.1 - 0.037 13.9 0.0 0.076 12.8 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KIY42813.1 - 0.064 12.9 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) HMG_box_2 PF09011.10 KIY42817.1 - 0.034 14.7 0.1 0.097 13.3 0.1 1.8 1 0 0 1 1 1 0 HMG-box domain Macoilin PF09726.9 KIY42817.1 - 0.088 11.4 4.0 0.15 10.6 4.0 1.3 1 0 0 1 1 1 0 Macoilin family DUF1178 PF06676.11 KIY42817.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) Sporozoite_P67 PF05642.11 KIY42817.1 - 0.19 9.8 7.9 0.27 9.2 7.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 KIY42817.1 - 1.8 6.7 8.4 2.8 6.1 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM220 PF15487.6 KIY42817.1 - 2.9 7.4 5.4 5.3 6.6 5.4 1.4 1 0 0 1 1 1 0 FAM220 family DUF2057 PF09829.9 KIY42817.1 - 8 6.6 9.0 4.4 7.4 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) BLOC1_2 PF10046.9 KIY42818.1 - 0.067 13.5 0.9 14 6.0 0.3 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HALZ PF02183.18 KIY42818.1 - 3 8.1 5.7 11 6.4 0.2 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper 2OG-FeII_Oxy_3 PF13640.6 KIY42819.1 - 0.13 13.2 0.0 0.28 12.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily KDZ PF18758.1 KIY42820.1 - 4e-24 85.5 0.0 5.9e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY42820.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY42820.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY42821.1 - 2.3e-40 138.6 0.2 4.2e-40 137.7 0.0 1.5 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase BLOC1_2 PF10046.9 KIY42821.1 - 0.0077 16.5 1.5 0.027 14.8 0.4 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.14 KIY42821.1 - 0.026 14.9 1.1 0.044 14.1 1.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4224 PF13986.6 KIY42822.1 - 0.017 15.0 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Vir_act_alpha_C PF10400.9 KIY42822.1 - 0.025 15.3 2.0 2 9.2 0.5 2.5 2 0 0 2 2 2 0 Virulence activator alpha C-term SHR-BD PF06650.12 KIY42822.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 SHR-binding domain of vacuolar-sorting associated protein 13 APH PF01636.23 KIY42823.1 - 7.1e-14 52.3 0.0 9.6e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY42823.1 - 2.9e-06 27.0 0.0 5.6e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KIY42823.1 - 0.042 13.2 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Leu_zip PF15294.6 KIY42824.1 - 0.043 13.3 0.7 0.074 12.6 0.7 1.4 1 0 0 1 1 1 0 Leucine zipper BBP1_C PF15272.6 KIY42824.1 - 0.093 12.6 3.3 0.15 11.9 3.3 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DDE_Tnp_4 PF13359.6 KIY42825.1 - 1.1e-13 51.1 0.0 1.6e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIY42825.1 - 0.0047 16.6 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain p450 PF00067.22 KIY42826.1 - 6.2e-05 21.9 0.0 6.2e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L30_N PF08079.12 KIY42828.1 - 4.2e-27 94.2 15.0 4.2e-27 94.2 15.0 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KIY42828.1 - 1.2e-12 47.5 0.9 2.8e-12 46.3 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 KIY42828.1 - 0.26 11.1 2.2 0.28 11.0 0.0 1.9 2 1 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter HMG_box PF00505.19 KIY42831.1 - 0.018 15.4 0.2 0.052 14.0 0.2 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY42831.1 - 0.034 14.8 0.2 0.078 13.6 0.2 1.6 1 0 0 1 1 1 0 HMG-box domain FoP_duplication PF13865.6 KIY42831.1 - 5.3 7.7 11.0 14 6.3 11.0 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 E1_dh PF00676.20 KIY42832.1 - 7.6e-05 21.8 0.0 8.1e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Myosin_N PF02736.19 KIY42832.1 - 0.036 13.9 0.0 7.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain PI3Ka PF00613.20 KIY42834.1 - 3.5e-56 189.5 0.1 5.7e-56 188.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KIY42834.1 - 1.9e-42 145.8 0.0 1.7e-39 136.1 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KIY42834.1 - 7.4e-41 139.3 0.0 1.3e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 KIY42834.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 C2 domain DUF3552 PF12072.8 KIY42836.1 - 6e-07 29.1 3.3 8.5e-07 28.6 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF4200 PF13863.6 KIY42836.1 - 0.0069 16.8 5.0 0.011 16.2 5.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) MCU PF04678.13 KIY42836.1 - 0.012 15.7 0.4 0.02 15.0 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter OmpH PF03938.14 KIY42836.1 - 0.03 14.7 0.9 0.04 14.2 0.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CAS_C PF12026.8 KIY42836.1 - 2.3 8.3 3.8 19 5.3 0.3 2.1 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain AAA PF00004.29 KIY42837.1 - 1.5e-41 141.9 0.0 2.6e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIY42837.1 - 1.8e-10 40.6 0.0 3.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KIY42837.1 - 1.9e-09 37.1 0.3 4.1e-09 36.1 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIY42837.1 - 2.9e-06 27.5 0.0 6.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KIY42837.1 - 2.4e-05 23.6 0.0 4.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KIY42837.1 - 3.1e-05 24.3 0.2 0.029 14.6 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KIY42837.1 - 0.00026 21.4 0.2 0.0089 16.4 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KIY42837.1 - 0.00046 20.0 0.0 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY42837.1 - 0.00061 19.8 0.2 0.0036 17.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 KIY42837.1 - 0.0041 16.5 0.2 0.24 10.7 0.1 2.3 1 1 1 2 2 2 1 KaiC AAA_3 PF07726.11 KIY42837.1 - 0.0052 16.6 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIY42837.1 - 0.0064 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIY42837.1 - 0.0082 16.2 0.1 0.042 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIY42837.1 - 0.0094 16.5 0.2 0.022 15.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KIY42837.1 - 0.023 14.4 0.1 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 KIY42837.1 - 0.028 14.6 0.4 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KIY42837.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KIY42837.1 - 0.047 12.9 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 KIY42837.1 - 0.049 13.5 0.1 0.76 9.7 0.1 2.4 1 1 1 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 KIY42837.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KIY42837.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KIY42837.1 - 0.11 11.7 0.0 0.6 9.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KIY42837.1 - 0.11 12.2 0.3 0.34 10.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIY42837.1 - 0.13 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Di19_C PF14571.6 KIY42837.1 - 0.13 12.8 0.3 0.34 11.4 0.0 1.9 2 0 0 2 2 1 0 Stress-induced protein Di19, C-terminal Mg_chelatase PF01078.21 KIY42837.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIY42837.1 - 0.22 11.1 0.7 4.5 6.8 0.3 2.6 1 1 1 2 2 2 0 AAA domain Asp PF00026.23 KIY42838.1 - 1.5e-43 149.4 15.2 2.7e-43 148.6 15.2 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY42838.1 - 0.0011 19.3 2.5 0.0052 17.0 0.2 2.9 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY42838.1 - 0.028 15.0 1.0 1.3 9.7 0.1 2.8 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KIY42838.1 - 0.072 12.9 3.8 4 7.2 0.1 2.7 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal ERG4_ERG24 PF01222.17 KIY42839.1 - 2.9e-139 464.6 6.0 3.2e-139 464.4 6.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIY42839.1 - 4.5e-06 26.3 0.2 1.2e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KIY42839.1 - 3.3e-05 24.2 0.0 3.3e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 KIY42839.1 - 0.00012 22.5 0.0 0.0005 20.4 0.0 2.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family E1_dh PF00676.20 KIY42840.1 - 0.0018 17.3 1.9 0.12 11.3 0.0 2.0 1 1 1 2 2 2 2 Dehydrogenase E1 component zf-H2C2_5 PF13909.6 KIY42841.1 - 7.3e-14 51.2 32.0 1.6e-06 27.8 0.5 8.7 9 0 0 9 9 9 4 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY42841.1 - 1.3e-13 50.5 43.3 0.0088 16.5 1.2 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type Transpos_assoc PF13963.6 KIY42841.1 - 4.8e-07 30.0 9.7 0.012 15.9 0.3 4.8 3 1 1 4 4 4 2 Transposase-associated domain zf-C2H2_4 PF13894.6 KIY42841.1 - 4.3e-06 27.1 43.5 0.02 15.7 0.7 8.5 8 0 0 8 8 8 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY42841.1 - 3.3e-05 24.1 40.4 0.017 15.5 0.5 8.1 9 0 0 9 9 8 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 KIY42841.1 - 0.0047 17.1 15.2 0.033 14.3 0.2 3.8 2 1 0 3 3 3 2 Aberrant zinc-finger zf-C2H2_9 PF16293.5 KIY42841.1 - 0.041 13.7 9.0 7 6.6 0.2 5.0 3 1 2 5 5 5 0 C2H2 type zinc-finger (1 copy) zf_CopZ PF18423.1 KIY42841.1 - 0.051 13.5 11.1 1.7 8.6 0.0 5.3 4 1 0 4 4 4 0 Zinc binding domain IBR PF01485.21 KIY42841.1 - 0.11 12.8 26.7 1.2 9.4 2.1 5.3 3 2 2 5 5 5 0 IBR domain, a half RING-finger domain OrsD PF12013.8 KIY42841.1 - 0.16 12.4 25.7 1.9 9.0 0.1 6.8 4 2 2 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_7 PF15269.6 KIY42841.1 - 0.47 10.6 12.6 5.8 7.1 0.1 4.6 3 1 1 4 4 4 0 Zinc-finger Zap1_zf2 PF18217.1 KIY42841.1 - 1.6 8.8 3.8 9.9 6.3 0.4 3.5 3 0 0 3 3 3 0 Zap1 zinc finger 2 FOXP-CC PF16159.5 KIY42841.1 - 4 8.1 25.3 11 6.8 4.0 6.2 3 2 1 5 5 5 0 FOXP coiled-coil domain NTP_transf_9 PF04248.12 KIY42842.1 - 1.5e-30 104.9 0.1 1.6e-25 88.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) eIF-5_eIF-2B PF01873.17 KIY42843.1 - 7.6e-28 96.7 0.8 1.1e-25 89.7 0.8 2.4 1 1 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KIY42843.1 - 1.3e-24 86.1 6.4 1.2e-23 83.1 0.0 3.5 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Pyridoxal_deC PF00282.19 KIY42845.1 - 2.4e-18 66.0 0.0 1.3e-11 43.8 0.0 2.7 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain LisH_2 PF16045.5 KIY42845.1 - 0.021 13.8 0.1 0.043 12.9 0.1 1.5 1 0 0 1 1 1 0 LisH Mito_fiss_reg PF05308.11 KIY42848.1 - 0.028 14.5 1.2 0.031 14.4 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KIY42848.1 - 0.15 11.5 6.1 0.18 11.2 6.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KIY42848.1 - 0.2 11.7 4.0 0.28 11.2 4.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cytochrom_B558a PF05038.13 KIY42848.1 - 0.24 10.9 1.5 0.29 10.7 1.5 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit PI-PLC-X PF00388.19 KIY42849.1 - 1.5e-49 167.3 0.0 1.3e-47 161.0 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIY42849.1 - 3.7e-42 143.3 0.0 5.9e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KIY42849.1 - 1.5e-07 31.6 0.0 8.2e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 C2 domain DUF2113 PF09886.9 KIY42849.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) THUMP PF02926.17 KIY42850.1 - 3.4e-09 36.9 0.0 6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 THUMP domain TEA PF01285.18 KIY42851.1 - 3.5e-14 52.6 0.1 7.6e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Ground-like PF04155.18 KIY42851.1 - 0.025 15.2 0.1 0.04 14.6 0.1 1.3 1 0 0 1 1 1 0 Ground-like domain His_Phos_2 PF00328.22 KIY42852.1 - 4.5e-34 118.4 0.0 6e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NUDIX PF00293.28 KIY42853.1 - 1e-13 51.5 0.2 1.2e-13 51.2 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.22 KIY42854.1 - 3.1e-44 151.6 20.3 2.1e-42 145.5 20.3 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF5379 PF17350.2 KIY42854.1 - 0.93 9.8 5.1 25 5.2 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5379) Formyl_trans_N PF00551.19 KIY42855.1 - 1.8e-13 50.6 0.0 2.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KIY42855.1 - 0.015 15.5 0.0 0.079 13.2 0.0 2.1 1 1 0 1 1 1 0 Formyl transferase, C-terminal domain ArfGap PF01412.18 KIY42856.1 - 0.036 14.1 0.3 0.13 12.3 0.3 1.9 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Pox_A12 PF04651.13 KIY42856.1 - 1.4 8.9 6.0 2.6 8.0 6.0 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein zf-C3HC4_3 PF13920.6 KIY42856.1 - 3.9 7.4 7.8 1.8 8.5 3.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CRAL_TRIO PF00650.20 KIY42857.1 - 2.2e-29 102.3 0.0 3.5e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY42857.1 - 1e-14 54.4 0.3 2e-14 53.5 0.3 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIY42857.1 - 0.042 14.0 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Glyco_hydro_10 PF00331.20 KIY42858.1 - 5.6e-97 324.7 0.0 7e-97 324.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Abhydrolase_1 PF00561.20 KIY42859.1 - 2.2e-34 119.3 0.0 2.9e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY42859.1 - 6.1e-12 45.3 0.0 1.6e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY42859.1 - 2.9e-09 37.8 0.0 5.7e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KIY42859.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.21 KIY42859.1 - 0.028 13.9 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.14 KIY42859.1 - 0.03 13.0 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family SH2_2 PF14633.6 KIY42862.1 - 5e-46 156.8 0.2 9.6e-46 155.9 0.2 1.4 1 0 0 1 1 1 1 SH2 domain SH2 PF00017.24 KIY42862.1 - 6.9e-05 22.9 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain GIT_CC PF16559.5 KIY42862.1 - 0.00089 19.1 0.3 0.0026 17.6 0.3 1.8 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor gag-asp_proteas PF13975.6 KIY42864.1 - 1.2e-05 25.8 0.0 3.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 KIY42864.1 - 0.0021 18.0 6.1 0.0055 16.7 6.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIY42864.1 - 0.0031 17.3 3.0 0.0031 17.3 3.0 2.3 2 0 0 2 2 2 1 Zinc knuckle Asp_protease PF09668.10 KIY42864.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Clr5 PF14420.6 KIY42864.1 - 0.034 14.4 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 Clr5 domain Asp_protease_2 PF13650.6 KIY42864.1 - 0.06 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RNase_H2-Ydr279 PF09468.10 KIY42866.1 - 1.2 9.3 4.7 2.1 8.5 3.1 2.1 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Tet_JBP PF12851.7 KIY42867.1 - 0.045 13.1 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily ATP_bind_1 PF03029.17 KIY42869.1 - 3.7e-17 62.9 1.0 4.3e-17 62.7 1.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein PGK PF00162.19 KIY42870.1 - 5.5e-87 292.2 0.0 6.6e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase HLH PF00010.26 KIY42871.1 - 1e-11 44.6 0.0 2.9e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Plavaka PF18759.1 KIY42872.1 - 1.7e-97 326.6 0.8 3.1e-97 325.7 0.8 1.4 1 0 0 1 1 1 1 Plavaka transposase Nucleoporin2 PF04096.14 KIY42877.1 - 1.3e-45 155.2 0.0 1.9e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Kelch_1 PF01344.25 KIY42877.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Kelch motif CNH PF00780.22 KIY42878.1 - 0.00098 18.8 0.0 0.041 13.5 0.0 2.1 2 0 0 2 2 2 2 CNH domain MINDY_DUB PF04424.13 KIY42879.1 - 6.4e-28 97.1 0.0 1.2e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase Herpes_Helicase PF02689.14 KIY42880.1 - 9.7e-06 23.8 0.0 1e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KIY42880.1 - 0.00014 21.6 0.1 0.0006 19.6 0.1 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF5605 PF18310.1 KIY42880.1 - 0.084 12.8 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) SMK-1 PF04802.15 KIY42881.1 - 1.3e-74 250.2 0.2 2.7e-74 249.1 0.2 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 MINDY_DUB PF04424.13 KIY42882.1 - 6.4e-28 97.1 0.0 1.2e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase CNH PF00780.22 KIY42883.1 - 0.0015 18.2 0.0 0.044 13.4 0.0 2.1 2 0 0 2 2 2 2 CNH domain Nucleoporin2 PF04096.14 KIY42884.1 - 1.3e-45 155.2 0.0 1.9e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Kelch_1 PF01344.25 KIY42884.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Kelch motif RTA1 PF04479.13 KIY42885.1 - 5.5e-27 94.7 8.5 5.5e-27 94.7 8.5 2.5 2 1 0 2 2 2 1 RTA1 like protein HNH_2 PF13391.6 KIY42886.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease APH PF01636.23 KIY42887.1 - 7.7e-10 39.1 0.2 2.9e-09 37.2 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY42887.1 - 1.8e-06 27.7 0.0 5e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KIY42887.1 - 0.00022 20.7 0.0 0.00073 19.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 KIY42887.1 - 0.00055 19.6 0.1 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KIY42887.1 - 0.003 16.9 0.0 0.0094 15.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KIY42887.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase EcKinase PF02958.20 KIY42887.1 - 0.082 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Haspin_kinase PF12330.8 KIY42887.1 - 0.084 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIY42889.1 - 4.8e-10 39.8 0.1 1e-09 38.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY42889.1 - 2e-06 27.6 0.0 7.6e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KIY42889.1 - 0.00037 19.9 0.0 0.0008 18.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 KIY42889.1 - 0.00097 18.8 0.1 0.003 17.2 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KIY42889.1 - 0.0032 16.9 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KIY42889.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase EcKinase PF02958.20 KIY42889.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase SIR2 PF02146.17 KIY42890.1 - 7.8e-32 110.6 0.0 3.5e-31 108.5 0.0 2.0 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KIY42890.1 - 0.0075 16.0 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.16 KIY42890.1 - 0.15 11.0 0.0 14 4.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit DIOX_N PF14226.6 KIY42892.1 - 8.2e-16 58.8 0.0 1.5e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY42892.1 - 1e-06 29.2 0.0 1.9e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_pol_Rpb2_6 PF00562.28 KIY42894.1 - 2.3e-112 375.9 0.0 4.8e-112 374.9 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIY42894.1 - 4e-31 108.1 0.0 8.1e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KIY42894.1 - 1.9e-28 98.4 0.0 4.7e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KIY42894.1 - 2.1e-21 75.7 0.0 5e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KIY42894.1 - 9.6e-18 64.4 0.1 6.8e-15 55.3 0.1 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KIY42894.1 - 5.8e-17 62.0 0.0 1.5e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 His_Phos_2 PF00328.22 KIY42898.1 - 0.00028 20.4 0.0 0.0044 16.4 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) APH PF01636.23 KIY42902.1 - 5.5e-10 39.6 0.3 1.5e-09 38.2 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY42902.1 - 1e-06 28.5 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KIY42902.1 - 0.00088 18.7 0.0 0.0018 17.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 KIY42902.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIY42902.1 - 0.0047 16.3 0.1 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KIY42902.1 - 0.018 14.4 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase EcKinase PF02958.20 KIY42902.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Haspin_kinase PF12330.8 KIY42902.1 - 0.24 10.3 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Methyltransf_11 PF08241.12 KIY42903.1 - 6.5e-11 42.7 0.2 1.3e-09 38.5 0.2 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY42903.1 - 3.5e-09 37.3 0.3 1.1e-06 29.3 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY42903.1 - 4.6e-09 36.3 0.0 3.6e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY42903.1 - 6.8e-09 36.4 0.7 8.1e-07 29.7 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY42903.1 - 5.2e-07 29.6 0.0 9.1e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY42903.1 - 9.5e-06 25.1 0.0 0.019 14.3 0.0 2.9 2 1 1 3 3 3 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIY42903.1 - 3e-05 23.6 0.0 0.0069 15.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KIY42903.1 - 0.0043 16.4 0.0 0.094 12.0 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KIY42903.1 - 0.0094 15.8 0.0 0.15 11.8 0.0 2.1 1 1 1 2 2 2 1 Hypothetical methyltransferase DUF1992 PF09350.10 KIY42904.1 - 2.6e-05 24.3 1.2 3.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) adh_short_C2 PF13561.6 KIY42905.1 - 5.3e-55 186.5 2.4 6.1e-55 186.3 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY42905.1 - 2.6e-46 157.5 0.9 3.2e-46 157.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY42905.1 - 2.9e-14 53.4 0.5 4e-14 52.9 0.5 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIY42905.1 - 0.013 14.8 1.2 0.029 13.7 0.0 2.1 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KIY42905.1 - 0.2 11.0 0.0 2.1 7.6 0.0 2.1 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) SKI PF01202.22 KIY42906.1 - 0.0076 16.4 0.0 0.054 13.6 0.0 2.0 1 1 0 1 1 1 1 Shikimate kinase SseC PF04888.12 KIY42906.1 - 0.01 15.5 0.3 0.014 15.0 0.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family zf-CCHC PF00098.23 KIY42907.1 - 5.8e-05 23.0 38.0 0.00077 19.4 3.2 4.9 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 KIY42907.1 - 0.08 12.8 0.2 0.08 12.8 0.2 4.6 6 0 0 6 6 6 0 Zinc knuckle zf-CCHC_4 PF14392.6 KIY42907.1 - 1.7 8.5 23.5 0.96 9.2 1.3 4.7 4 1 1 5 5 5 0 Zinc knuckle DZR PF12773.7 KIY42907.1 - 2 8.5 21.3 70 3.6 7.9 3.6 1 1 1 2 2 2 0 Double zinc ribbon zf-CCHC_3 PF13917.6 KIY42907.1 - 6.4 6.8 30.7 2.1 8.4 0.4 5.0 2 1 3 5 5 5 0 Zinc knuckle SHD1 PF03983.12 KIY42908.1 - 3.4e-31 106.9 0.1 1e-30 105.3 0.0 1.9 2 0 0 2 2 2 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 KIY42908.1 - 3.2e-30 103.5 5.6 6.9e-12 44.8 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KIY42908.1 - 4.3e-28 96.9 10.9 1.1e-10 41.2 0.1 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KIY42908.1 - 3e-15 55.6 0.2 4.5e-05 23.0 0.0 4.5 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.11 KIY42908.1 - 0.0024 18.1 6.4 8.5 6.8 0.2 4.4 4 0 0 4 4 4 2 Bacterial SH3 domain SAM_4 PF18017.1 KIY42908.1 - 0.0034 17.3 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIY42908.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CDC45 PF02724.14 KIY42908.1 - 8.6 4.5 7.0 13 3.9 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.27 KIY42909.1 - 6.6e-18 65.5 0.0 1.2e-17 64.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY42909.1 - 7.2e-10 39.2 2.3 6.7e-05 22.8 0.4 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY42909.1 - 0.00045 19.9 0.1 0.00098 18.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIY42909.1 - 0.00086 19.9 0.0 0.0013 19.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIY42909.1 - 0.0011 18.9 0.1 0.0017 18.3 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KIY42909.1 - 0.0018 17.9 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KIY42909.1 - 0.0035 17.0 0.2 0.0054 16.4 0.2 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KIY42909.1 - 0.0037 17.0 0.0 0.0051 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ATP-synt_ab PF00006.25 KIY42909.1 - 0.0044 16.7 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 KIY42909.1 - 0.0055 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain VirE PF05272.11 KIY42909.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E MMR_HSR1 PF01926.23 KIY42909.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KIY42909.1 - 0.022 14.0 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin SMC_N PF02463.19 KIY42909.1 - 0.023 14.1 0.3 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 KIY42909.1 - 0.035 13.7 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 KIY42909.1 - 0.061 12.1 2.6 0.25 10.1 0.2 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.18 KIY42909.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KIY42909.1 - 0.075 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KIY42909.1 - 0.084 12.8 0.1 0.2 11.6 0.1 1.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 KIY42909.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KIY42909.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 KIY42909.1 - 0.19 12.0 0.1 0.3 11.3 0.1 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KIY42909.1 - 0.21 11.9 0.7 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KIY42909.1 - 0.24 11.1 0.1 0.38 10.5 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Opy2 PF09463.10 KIY42910.1 - 0.01 16.1 16.7 0.019 15.3 16.7 1.5 1 0 0 1 1 1 0 Opy2 protein DUF3301 PF11743.8 KIY42910.1 - 0.18 11.5 0.7 0.3 10.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) DS PF01916.17 KIY42911.1 - 1.2e-124 415.3 0.0 3e-124 414.0 0.0 1.6 1 1 0 1 1 1 1 Deoxyhypusine synthase GTP_EFTU PF00009.27 KIY42912.1 - 1.6e-45 155.1 0.0 2.1e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIY42912.1 - 2.1e-29 102.1 2.9 3.7e-29 101.3 0.2 2.9 3 1 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIY42912.1 - 9.4e-12 45.2 1.5 1.6e-11 44.5 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY42912.1 - 0.00057 19.9 0.1 0.0031 17.6 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY42912.1 - 0.0016 18.4 0.4 2.1 8.2 0.0 2.7 2 1 1 3 3 3 2 RsgA GTPase Peptidase_U32_C PF16325.5 KIY42912.1 - 0.16 12.3 0.0 0.47 10.8 0.0 1.8 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain Aminotran_1_2 PF00155.21 KIY42913.1 - 9.9e-17 61.1 0.0 2.3e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II 14-3-3 PF00244.20 KIY42914.1 - 2.4e-75 252.8 0.3 2.8e-75 252.6 0.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Med26_M PF15694.5 KIY42915.1 - 0.0058 16.7 0.6 0.0096 16.0 0.6 1.3 1 0 0 1 1 1 1 Mediator complex subunit 26 middle domain DUF4131 PF13567.6 KIY42915.1 - 0.11 12.2 4.6 0.079 12.6 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HMG_box_2 PF09011.10 KIY42916.1 - 0.026 15.1 0.0 0.05 14.2 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain Gp-FAR-1 PF05823.12 KIY42916.1 - 0.04 14.3 0.2 8.5 6.7 0.0 2.0 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Peptidase_M42 PF05343.14 KIY42916.1 - 0.091 11.8 0.1 0.15 11.1 0.0 1.4 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase MMPL PF03176.15 KIY42916.1 - 0.19 10.6 0.1 0.21 10.5 0.1 1.0 1 0 0 1 1 1 0 MMPL family Tet_JBP PF12851.7 KIY42917.1 - 0.032 13.6 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily PBP1_TM PF14812.6 KIY42918.1 - 0.0026 18.1 10.6 0.0064 16.8 10.6 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Hemopexin PF00045.19 KIY42918.1 - 0.037 14.0 0.4 0.4 10.7 0.6 2.3 2 0 0 2 2 2 0 Hemopexin DNA_pol_phi PF04931.13 KIY42918.1 - 1.4 7.0 4.0 1.6 6.7 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 KIY42918.1 - 1.4 7.4 13.1 2.4 6.7 13.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF5363 PF17320.2 KIY42920.1 - 0.064 13.1 0.6 0.24 11.3 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5363) CKS PF01111.19 KIY42923.1 - 2.4e-35 120.6 0.5 2.8e-35 120.4 0.5 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Pkinase PF00069.25 KIY42924.1 - 1.5e-19 70.4 0.0 1.2e-18 67.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY42924.1 - 8.6e-13 48.2 0.1 8.6e-12 44.9 0.2 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KIY42924.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIY42924.1 - 0.079 12.9 0.2 0.34 10.8 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY42924.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GPI-anchored PF10342.9 KIY42926.1 - 0.00014 22.6 0.6 0.00022 21.9 0.6 1.3 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family COesterase PF00135.28 KIY42927.1 - 5.7e-63 213.5 0.0 6.9e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY42927.1 - 1e-13 51.7 0.0 1.9e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY42927.1 - 0.0056 15.6 0.0 0.028 13.3 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase DEAD PF00270.29 KIY42928.1 - 4.5e-18 65.6 0.0 1.1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 KIY42928.1 - 5.8e-14 51.9 0.1 3.6e-11 42.7 0.0 2.2 1 1 1 2 2 2 2 Sec63 Brl domain Helicase_C PF00271.31 KIY42928.1 - 6.5e-09 36.1 0.0 4.5e-08 33.4 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY42928.1 - 1.7e-05 24.9 0.0 5.4e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY42928.1 - 0.021 15.1 0.0 0.34 11.2 0.0 2.9 3 1 0 3 3 3 0 AAA domain DEAD PF00270.29 KIY42929.1 - 9e-41 139.6 0.1 1.5e-40 138.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KIY42929.1 - 4.6e-23 81.2 0.3 4.6e-23 81.2 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KIY42929.1 - 3.4e-18 66.0 0.1 1.5e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY42929.1 - 3.6e-06 27.1 1.1 5.5e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY42929.1 - 0.031 14.6 0.1 0.18 12.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KIY42929.1 - 0.038 13.5 1.8 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Folliculin PF11704.8 KIY42929.1 - 0.34 10.8 3.1 0.84 9.5 3.1 1.7 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SecA_DEAD PF07517.14 KIY42929.1 - 3.2 7.0 6.0 2.8 7.2 0.0 3.2 4 0 0 4 4 4 0 SecA DEAD-like domain Hydantoinase_B PF02538.14 KIY42931.1 - 9.5e-206 684.2 0.1 1.5e-205 683.5 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KIY42931.1 - 9.8e-94 313.9 0.5 3.5e-93 312.0 0.1 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIY42931.1 - 1.3e-61 207.4 0.2 2.2e-59 200.2 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Bestrophin PF01062.21 KIY42932.1 - 4e-18 65.8 3.3 2.6e-10 40.2 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel YibE_F PF07907.11 KIY42932.1 - 1 8.8 5.4 0.18 11.3 1.2 1.7 2 0 0 2 2 2 0 YibE/F-like protein EIIC-GAT PF03611.14 KIY42932.1 - 2.8 7.0 8.7 6 5.8 8.3 1.7 1 1 0 1 1 1 0 PTS system sugar-specific permease component Acetyltransf_1 PF00583.25 KIY42935.1 - 1e-09 38.6 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY42935.1 - 7e-09 36.0 0.2 1.2e-08 35.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY42935.1 - 2.6e-07 30.6 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY42935.1 - 8.9e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein GATA PF00320.27 KIY42936.1 - 6.2e-14 51.3 4.7 1.4e-13 50.2 4.7 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KIY42936.1 - 7.6e-05 22.9 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KIY42936.1 - 0.0069 16.4 0.0 0.044 13.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KIY42936.1 - 0.0071 16.6 0.0 0.024 14.9 0.0 1.9 2 0 0 2 2 2 1 PAS domain Nudix_N_2 PF14803.6 KIY42936.1 - 0.08 12.9 1.9 7.4 6.6 0.3 2.7 2 0 0 2 2 2 0 Nudix N-terminal WD40 PF00400.32 KIY42938.1 - 4.1e-38 128.7 30.0 1.7e-05 25.4 0.3 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KIY42938.1 - 1.2e-14 53.9 1.6 2.4e-14 52.9 1.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY42938.1 - 3.2e-13 49.2 1.0 7.6e-13 48.0 0.7 1.9 1 1 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KIY42938.1 - 2.6e-07 30.8 0.1 0.29 11.5 0.0 5.1 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY42938.1 - 1.9e-05 23.5 10.5 0.25 9.9 0.2 5.3 3 1 3 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIY42938.1 - 0.12 12.0 4.7 8.2 5.9 0.7 3.0 3 0 0 3 3 3 0 PQQ-like domain F-box_4 PF15966.5 KIY42938.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 F-box PALB2_WD40 PF16756.5 KIY42938.1 - 3.4 6.5 6.0 49 2.7 0.0 3.7 3 1 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain SH3_9 PF14604.6 KIY42939.1 - 4.2e-11 42.5 0.0 4.5e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY42939.1 - 1.3e-07 31.1 0.0 1.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIY42939.1 - 1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KIY42939.1 - 0.19 12.2 0.0 0.21 12.0 0.0 1.1 1 0 0 1 1 1 0 Helically-extended SH3 domain TPR_1 PF00515.28 KIY42940.1 - 2.5e-05 23.9 0.0 0.82 9.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KIY42940.1 - 4.5e-05 22.8 0.0 9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIY42940.1 - 0.00015 22.2 0.6 0.0013 19.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.6 KIY42940.1 - 0.00036 21.1 6.6 2.3 9.3 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY42940.1 - 0.00041 20.6 17.5 0.012 15.9 0.2 6.7 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY42940.1 - 0.007 16.3 2.4 1.5 9.0 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.6 KIY42940.1 - 0.0092 16.3 0.0 0.054 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain SNAP PF14938.6 KIY42940.1 - 0.021 14.2 0.2 0.66 9.3 0.0 2.8 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KIY42940.1 - 0.038 13.4 3.2 0.24 10.7 2.3 2.8 1 1 1 2 2 2 0 MalT-like TPR region RPN7 PF10602.9 KIY42940.1 - 0.056 13.2 0.1 2.1 8.0 0.0 2.8 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KIY42940.1 - 0.2 11.6 3.6 0.54 10.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY42940.1 - 0.25 12.0 6.9 4.9 7.9 0.3 4.0 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY42940.1 - 4 8.3 5.8 1.1e+02 3.8 0.3 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY42940.1 - 4 7.8 13.6 64 4.0 0.0 6.3 7 1 1 8 8 6 0 Tetratricopeptide repeat Kinesin PF00225.23 KIY42941.1 - 9.3e-97 323.9 6.5 4.7e-54 183.5 0.0 4.0 4 0 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 KIY42941.1 - 1.5e-20 73.7 0.0 6e-20 71.7 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Fib_alpha PF08702.10 KIY42941.1 - 0.00062 20.0 4.7 0.00062 20.0 4.7 12.2 7 4 7 14 14 14 3 Fibrinogen alpha/beta chain family DUF2353 PF09789.9 KIY42941.1 - 0.004 16.6 24.6 0.004 16.6 24.6 9.5 5 3 4 9 9 9 2 Uncharacterized coiled-coil protein (DUF2353) adh_short_C2 PF13561.6 KIY42942.1 - 7.2e-51 173.0 0.2 8.7e-51 172.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY42942.1 - 5e-38 130.5 0.3 7e-38 130.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY42942.1 - 6.2e-11 42.5 0.6 1.4e-10 41.4 0.6 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY42942.1 - 0.015 14.8 0.1 0.044 13.3 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIY42942.1 - 0.18 10.9 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1604 PF07713.13 KIY42943.1 - 1e-39 134.2 0.6 1e-39 134.2 0.6 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KIY42943.1 - 6.3e-05 22.8 2.5 0.00017 21.4 0.3 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KIY42943.1 - 0.21 11.7 0.0 0.21 11.7 0.0 3.1 4 0 0 4 4 4 0 G-patch domain Glyco_hydro_5_C PF18564.1 KIY42944.1 - 9e-21 74.2 0.1 1.8e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KIY42944.1 - 2e-14 53.7 0.0 2.6e-09 36.9 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF4666 PF15697.5 KIY42946.1 - 0.041 14.6 0.9 0.066 13.9 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) Ribonuclease_T2 PF00445.18 KIY42947.1 - 6.8e-39 134.0 0.2 1e-38 133.4 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family PTN_MK_N PF05196.13 KIY42947.1 - 0.047 13.9 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain S-l_SbsC_C PF18316.1 KIY42947.1 - 0.11 12.9 0.0 0.37 11.3 0.0 1.9 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain Aha1_N PF09229.11 KIY42948.1 - 2.1e-33 115.5 0.3 3e-33 115.0 0.3 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KIY42948.1 - 2.2e-11 44.1 0.1 6.7e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein TTc_toxin_rep PF18807.1 KIY42948.1 - 0.1 12.4 0.2 24 4.9 0.1 2.6 2 0 0 2 2 2 0 Tripartite Tc toxins repeat MSA-2c PF12238.8 KIY42948.1 - 0.18 11.8 3.4 0.34 10.9 3.4 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c COesterase PF00135.28 KIY42949.1 - 0.028 13.3 0.0 0.072 11.9 0.0 1.5 1 1 0 1 1 1 0 Carboxylesterase family zf-AN1 PF01428.16 KIY42950.1 - 1e-08 35.2 7.8 1e-08 35.2 7.8 1.8 1 1 0 1 1 1 1 AN1-like Zinc finger Rubredoxin_2 PF18073.1 KIY42950.1 - 0.033 13.9 0.2 0.033 13.9 0.2 2.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain PACT_coil_coil PF10495.9 KIY42950.1 - 0.083 13.5 0.1 0.11 13.1 0.1 1.2 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein IBR PF01485.21 KIY42950.1 - 0.14 12.4 9.0 0.18 12.1 8.3 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Dimer_Tnp_hAT PF05699.14 KIY42956.1 - 9.7e-19 67.0 0.2 1.1e-18 66.8 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIY42957.1 - 3.4e-06 27.3 0.0 4.3e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) ABC_tran PF00005.27 KIY42958.1 - 6.1e-21 75.4 0.0 8.1e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY42958.1 - 0.00024 20.6 0.0 0.0016 17.9 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIY42958.1 - 0.0015 17.4 0.1 0.0027 16.6 0.0 1.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 KIY42958.1 - 0.0024 17.7 0.1 0.05 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KIY42958.1 - 0.087 12.5 0.0 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY42958.1 - 0.14 12.5 0.2 4.9 7.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KIY42958.1 - 0.17 12.2 0.0 0.49 10.7 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4091 PF13320.6 KIY42961.1 - 0.13 12.4 1.1 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) YqhR PF11085.8 KIY42961.1 - 0.99 9.3 7.5 3.2 7.7 0.0 2.4 2 1 0 2 2 2 0 Conserved membrane protein YqhR MpPF26 PF07666.11 KIY42961.1 - 2.4 8.2 7.2 3.3 7.8 1.9 2.7 2 1 1 3 3 3 0 M penetrans paralogue family 26 RPN7 PF10602.9 KIY42962.1 - 3e-36 124.7 1.6 5.3e-36 123.9 1.6 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KIY42962.1 - 8.9e-16 58.3 0.0 3.6e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 KIY42962.1 - 0.019 15.0 0.1 17 5.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY42962.1 - 0.082 13.1 1.0 11 6.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LCAT PF02450.15 KIY42962.1 - 0.11 11.6 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1925 PF09094.11 KIY42963.1 - 0.15 12.4 0.4 0.36 11.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) WW PF00397.26 KIY42964.1 - 2.1e-09 37.3 6.1 4.3e-09 36.3 6.1 1.6 1 0 0 1 1 1 1 WW domain Usp PF00582.26 KIY42965.1 - 6e-05 23.6 0.2 8.9e-05 23.0 0.2 1.3 1 1 0 1 1 1 1 Universal stress protein family DHHC PF01529.20 KIY42966.1 - 1.8 8.6 5.7 3 7.9 2.3 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2950 PF11453.8 KIY42967.1 - 0.16 11.1 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Glyco_hydro_16 PF00722.21 KIY42968.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1708 PF08101.11 KIY42970.1 - 3e-12 46.5 0.0 3.3e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KIY42970.1 - 0.002 18.0 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain CAP59_mtransfer PF11735.8 KIY42971.1 - 2e-70 237.2 0.1 2.7e-70 236.8 0.1 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Disaggr_repeat PF06848.11 KIY42974.1 - 0.17 11.6 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Disaggregatase related repeat MFS_1 PF07690.16 KIY42975.1 - 4.1e-13 49.0 48.8 4.1e-13 49.0 48.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily IF-2B PF01008.17 KIY42976.1 - 3e-36 125.1 0.0 3.8e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KIY42976.1 - 9.2e-08 32.2 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GST_N_3 PF13417.6 KIY42977.1 - 1.7e-16 60.4 0.0 3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY42977.1 - 2.3e-14 53.4 0.0 4.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY42977.1 - 5.1e-12 46.0 0.0 8.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KIY42977.1 - 2e-06 27.9 0.0 4.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin Glyco_hydro_28 PF00295.17 KIY42978.1 - 3.5e-61 207.1 17.3 3.5e-61 207.1 17.3 1.4 1 1 1 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIY42978.1 - 2.2e-10 40.6 15.0 4.5e-09 36.4 12.2 2.4 2 0 0 2 2 2 2 Right handed beta helix region DUF1565 PF07602.11 KIY42978.1 - 3.3e-05 23.4 3.2 3.3e-05 23.4 3.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) DUF4957 PF16318.5 KIY42978.1 - 0.24 11.3 7.3 0.27 11.2 2.9 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4957) Ribosomal_L28 PF00830.19 KIY42980.1 - 2.3e-15 56.5 0.2 3.2e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L28 family GWT1 PF06423.12 KIY42981.1 - 2.2e-26 92.8 6.5 5.3e-17 62.3 2.7 3.0 2 1 1 3 3 3 2 GWT1 DUF2537 PF10801.8 KIY42981.1 - 0.086 13.1 4.5 0.22 11.7 1.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Abhydrolase_1 PF00561.20 KIY42982.1 - 4.4e-13 49.5 0.0 6.3e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY42982.1 - 7.8e-10 39.7 0.3 1e-09 39.3 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY42982.1 - 8.4e-07 28.5 0.0 4.5e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KIY42982.1 - 1.1e-05 25.2 0.0 0.00011 21.9 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 KIY42982.1 - 0.00064 19.6 0.2 0.72 9.6 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.18 KIY42982.1 - 0.077 12.5 0.0 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.14 KIY42982.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family ADH_N PF08240.12 KIY42983.1 - 6.2e-27 93.6 7.7 1e-26 92.9 7.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY42983.1 - 2.1e-14 53.6 0.0 5.9e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY42983.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peroxidase_2 PF01328.17 KIY42984.1 - 4.9e-43 147.8 0.0 8.5e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 GRIM-19 PF06212.12 KIY42986.1 - 0.13 12.2 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 GRIM-19 protein Spc7 PF08317.11 KIY42986.1 - 0.41 9.5 16.2 0.058 12.3 11.0 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Leu_zip PF15294.6 KIY42986.1 - 0.69 9.4 15.9 2.7 7.4 16.2 1.7 1 1 0 1 1 1 0 Leucine zipper Shugoshin_N PF07558.11 KIY42986.1 - 0.92 9.4 3.5 1.8 8.5 0.3 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region APG6_N PF17675.1 KIY42986.1 - 2.4 8.7 28.9 0.12 12.9 8.2 2.8 1 1 2 3 3 3 0 Apg6 coiled-coil region Wbp11 PF09429.10 KIY42986.1 - 3 8.3 13.5 4.6 7.7 3.3 3.5 2 1 1 3 3 3 0 WW domain binding protein 11 PikAIV_N PF18605.1 KIY42986.1 - 3.1 7.5 6.5 5 6.8 0.1 3.5 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TMCO5 PF14992.6 KIY42986.1 - 5.3 6.5 11.9 22 4.5 11.9 1.9 1 1 0 1 1 1 0 TMCO5 family DegS PF05384.11 KIY42986.1 - 6 6.3 19.2 0.33 10.4 3.2 3.2 2 1 1 3 3 3 0 Sensor protein DegS DUF4407 PF14362.6 KIY42986.1 - 6.2 6.1 13.7 5.6 6.2 12.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4_3 PF13920.6 KIY42988.1 - 9.9e-08 31.7 8.7 2.3e-07 30.6 8.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY42988.1 - 8.7e-06 25.5 10.4 1.6e-05 24.6 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY42988.1 - 4.1e-05 23.5 12.2 9.8e-05 22.2 12.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY42988.1 - 4.2e-05 23.8 10.2 6.8e-05 23.1 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY42988.1 - 0.00019 21.4 6.3 0.00019 21.4 6.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY42988.1 - 0.00062 19.6 6.0 0.00062 19.6 6.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY42988.1 - 0.034 14.0 13.3 0.31 10.9 13.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-WRNIP1_ubi PF18279.1 KIY42988.1 - 0.94 10.3 7.7 1 10.2 1.2 2.7 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C3HC4_4 PF15227.6 KIY42988.1 - 1.3 9.3 11.9 8.3 6.7 12.2 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Glyco_hydro_28 PF00295.17 KIY42989.1 - 1.6e-43 149.0 3.5 2.1e-43 148.6 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KIY42989.1 - 3.3e-08 33.6 5.7 1e-05 25.5 4.8 2.5 1 1 0 2 2 2 2 Pectate lyase superfamily protein Csm1 PF12539.8 KIY42989.1 - 0.097 13.3 0.0 0.29 11.8 0.0 1.8 1 0 0 1 1 1 0 Chromosome segregation protein Csm1/Pcs1 DUF1251 PF06856.11 KIY42989.1 - 0.14 11.8 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) HABP4_PAI-RBP1 PF04774.15 KIY42990.1 - 1.1e-05 26.2 3.2 1.4e-05 25.9 3.2 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF934 PF06073.12 KIY42992.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) TFIID-18kDa PF02269.16 KIY42993.1 - 2.7e-31 107.4 0.1 7.9e-31 105.9 0.1 1.7 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Anoct_dimer PF16178.5 KIY42993.1 - 0.0031 17.3 0.5 0.0048 16.6 0.5 1.2 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin TFIIE-A_C PF11521.8 KIY42993.1 - 0.11 12.7 9.0 0.3 11.4 7.6 2.1 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha Adaptin_binding PF10199.9 KIY42993.1 - 0.17 12.5 3.2 0.32 11.6 3.2 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Glyco_hydro_12 PF01670.16 KIY42995.1 - 1.6e-35 123.0 13.9 2e-35 122.7 13.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF2673 PF10880.8 KIY42995.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) PPV_E2_C PF00511.17 KIY42995.1 - 7.8 6.8 7.3 44 4.3 0.2 2.7 2 0 0 2 2 2 0 E2 (early) protein, C terminal COPIIcoated_ERV PF07970.12 KIY42996.1 - 3.1e-35 122.0 0.7 5.7e-35 121.2 0.7 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KIY42996.1 - 2.2e-20 72.8 0.0 3.6e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TIM PF00121.18 KIY42997.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Triosephosphate isomerase Glyco_hydro_28 PF00295.17 KIY42998.1 - 3.7e-63 213.5 16.4 4.6e-63 213.2 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIY42998.1 - 3.2e-12 46.6 9.6 3.2e-12 46.6 9.6 2.4 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 KIY42998.1 - 7.8e-07 28.6 2.2 7.8e-07 28.6 2.2 1.6 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KIY42998.1 - 1.6e-05 24.4 1.8 2.6e-05 23.7 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1565) DUF4957 PF16318.5 KIY42998.1 - 0.081 12.9 2.7 0.19 11.6 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4957) Orbi_VP1 PF05788.12 KIY42998.1 - 1.2 6.6 3.7 1.6 6.2 3.7 1.0 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) Hexokinase_2 PF03727.16 KIY43000.1 - 3e-82 275.7 0.0 3.9e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KIY43000.1 - 2.7e-65 220.0 0.0 3.8e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase She9_MDM33 PF05546.11 KIY43001.1 - 6.1e-74 248.1 8.3 8e-74 247.7 8.3 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family TPD52 PF04201.15 KIY43001.1 - 0.019 14.6 4.1 0.073 12.7 3.2 2.3 2 1 0 2 2 2 0 Tumour protein D52 family Self-incomp_S1 PF05938.11 KIY43002.1 - 0.052 14.1 0.0 0.063 13.8 0.0 1.1 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 TauD PF02668.16 KIY43003.1 - 1.5e-46 159.3 0.1 2.4e-46 158.7 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KIY43003.1 - 2.6e-06 28.0 0.1 5.7e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KIY43003.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.5 1 1 0 1 1 1 0 CsiD MaoC_dehydratas PF01575.19 KIY43004.1 - 1.2e-19 70.1 0.0 2.5e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIY43004.1 - 0.002 18.3 0.0 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Fungal_trans PF04082.18 KIY43005.1 - 2.5e-14 52.9 0.1 3.7e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY43005.1 - 6.5e-07 29.4 8.6 1.4e-06 28.3 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.12 KIY43005.1 - 0.026 14.5 0.1 0.098 12.7 0.1 1.9 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 OrfB_Zn_ribbon PF07282.11 KIY43005.1 - 0.87 9.6 3.3 1.9 8.5 3.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Nup54 PF13874.6 KIY43006.1 - 6e-34 117.1 2.3 1.1e-33 116.2 2.3 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KIY43006.1 - 1.2e-20 74.1 92.8 4.1e-11 43.6 34.7 4.1 2 1 1 3 3 3 2 Nucleoporin FG repeat region SUIM_assoc PF16619.5 KIY43006.1 - 1.1 9.3 12.6 0.56 10.3 2.4 3.6 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 zf-HC5HC2H_2 PF13832.6 KIY43007.1 - 0.021 15.0 1.0 0.021 15.0 1.0 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KIY43007.1 - 0.023 14.9 1.3 0.026 14.8 0.7 1.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain KDZ PF18758.1 KIY43009.1 - 1.5e-22 80.3 2.2 1.6e-22 80.2 2.2 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIY43010.1 - 0.0024 17.5 0.1 0.0047 16.6 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase p450 PF00067.22 KIY43011.1 - 1.1e-72 245.3 0.0 9.3e-72 242.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY43014.1 - 1.6e-68 231.6 0.1 3e-67 227.4 0.1 2.4 1 1 0 1 1 1 1 Cytochrome P450 PGA2 PF07543.12 KIY43016.1 - 1.3 9.0 3.3 26 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Phage_integrase PF00589.22 KIY43017.1 - 0.00013 21.8 0.1 0.00033 20.5 0.1 1.6 2 0 0 2 2 2 1 Phage integrase family Septin PF00735.18 KIY43018.1 - 3.7e-14 52.7 0.1 5.1e-09 35.8 0.0 2.0 2 0 0 2 2 2 2 Septin GTP_EFTU PF00009.27 KIY43018.1 - 0.06 12.9 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF5471 PF17565.2 KIY43019.1 - 0.07 13.4 0.7 6 7.2 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5471) Pkinase PF00069.25 KIY43020.1 - 0.0037 16.7 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Hemopexin PF00045.19 KIY43021.1 - 3.3e-15 55.8 1.0 0.00022 21.1 0.0 4.7 4 1 0 4 4 4 4 Hemopexin Ribonuc_red_sm PF00268.21 KIY43022.1 - 9.7e-110 366.4 0.1 1.1e-109 366.2 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain tRNA-synt_1d PF00750.19 KIY43023.1 - 2.5e-98 329.3 1.0 3.5e-98 328.8 1.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KIY43023.1 - 4.8e-22 78.4 0.2 1.2e-21 77.1 0.2 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain DUF1266 PF06889.11 KIY43023.1 - 0.096 12.7 0.1 5.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) HSF_DNA-bind PF00447.17 KIY43027.1 - 4e-32 110.7 1.0 1e-31 109.4 1.0 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KIY43027.1 - 1.9e-24 86.0 0.0 6.4e-24 84.3 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain TFIIA PF03153.13 KIY43027.1 - 0.013 15.5 5.9 0.019 15.0 5.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 KIY43027.1 - 0.17 9.9 6.1 0.27 9.3 6.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sds3 PF08598.11 KIY43027.1 - 0.23 11.4 5.6 0.41 10.6 5.6 1.3 1 0 0 1 1 1 0 Sds3-like SUIM_assoc PF16619.5 KIY43027.1 - 4.7 7.4 11.9 0.17 12.0 2.1 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NicO PF03824.16 KIY43030.1 - 5.7e-49 167.0 10.7 9.6e-48 162.9 2.0 2.4 2 1 0 2 2 2 2 High-affinity nickel-transport protein Ribosomal_L16 PF00252.18 KIY43031.1 - 5e-45 152.7 0.0 6.1e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Methyltransf_4 PF02390.17 KIY43032.1 - 3.1e-51 173.3 0.0 3.9e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KIY43032.1 - 0.00032 21.3 0.1 0.0021 18.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY43032.1 - 0.0077 16.0 0.1 0.11 12.3 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY43032.1 - 0.0096 16.6 0.0 0.024 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY43032.1 - 0.014 16.0 0.0 0.045 14.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIY43032.1 - 0.089 12.3 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Citrate_synt PF00285.21 KIY43033.1 - 2.5e-97 326.2 0.0 2.9e-97 326.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain SPAN PF02510.14 KIY43035.1 - 0.063 12.5 0.0 0.072 12.3 0.0 1.0 1 0 0 1 1 1 0 Surface presentation of antigens protein HALZ PF02183.18 KIY43038.1 - 0.0021 18.2 0.5 1.1 9.6 0.3 2.6 2 0 0 2 2 2 2 Homeobox associated leucine zipper CLZ PF16526.5 KIY43038.1 - 0.095 13.1 0.4 0.74 10.2 0.0 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF883 PF05957.13 KIY43038.1 - 0.61 10.7 3.9 4 8.1 0.8 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SlyX PF04102.12 KIY43038.1 - 0.62 10.7 4.0 4 8.1 0.1 3.4 4 0 0 4 4 4 0 SlyX Lebercilin PF15619.6 KIY43038.1 - 5.3 6.7 7.0 35 4.0 1.3 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 KIY43038.1 - 5.7 7.5 9.3 0.76 10.3 0.7 2.7 2 2 1 3 3 3 0 Cell division protein ZapB Tet_JBP PF12851.7 KIY43040.1 - 0.0028 17.0 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Phage_integrase PF00589.22 KIY43043.1 - 0.058 13.2 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Phage integrase family F-box-like PF12937.7 KIY43045.1 - 8e-07 28.9 3.3 1.3e-05 25.0 3.3 2.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY43045.1 - 0.69 9.9 8.5 5.8 6.9 0.0 3.8 3 1 0 3 3 3 0 F-box domain Leu_zip PF15294.6 KIY43047.1 - 0.05 13.1 2.5 0.05 13.1 2.5 1.2 1 0 0 1 1 1 0 Leucine zipper DivIC PF04977.15 KIY43047.1 - 0.066 13.0 0.7 0.11 12.3 0.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Ribosomal_S17_N PF16205.5 KIY43047.1 - 0.11 12.8 1.9 0.23 11.8 1.9 1.5 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal DUF829 PF05705.14 KIY43048.1 - 2.2e-10 40.8 0.4 4.1e-10 40.0 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) zf-CCHC_4 PF14392.6 KIY43052.1 - 0.00047 19.8 0.4 0.00079 19.1 0.4 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY43052.1 - 0.059 13.5 3.7 0.11 12.7 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 KIY43052.1 - 0.17 11.8 4.2 0.37 10.7 4.2 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1178 PF06676.11 KIY43054.1 - 0.0077 16.6 0.3 0.012 16.0 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1178) Hepar_II_III PF07940.13 KIY43054.1 - 0.027 14.1 0.1 0.031 13.9 0.1 1.0 1 0 0 1 1 1 0 Heparinase II/III-like protein HMG_box_2 PF09011.10 KIY43054.1 - 0.076 13.6 0.0 0.2 12.3 0.0 1.6 2 0 0 2 2 2 0 HMG-box domain DNA_pol_phi PF04931.13 KIY43055.1 - 0.26 9.3 16.7 0.33 9.0 16.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KIY43055.1 - 0.72 8.0 11.6 0.75 7.9 11.6 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KIY43055.1 - 2.2 7.6 9.5 2.2 7.6 9.5 1.1 1 0 0 1 1 1 0 SDA1 Tom22 PF04281.13 KIY43055.1 - 2.9 7.7 6.7 5.1 6.9 6.7 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 BUD22 PF09073.10 KIY43055.1 - 3.4 6.9 11.2 3.7 6.8 11.2 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 KIY43055.1 - 4.1 6.6 13.8 6 6.1 13.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3512 PF12024.8 KIY43056.1 - 0.0051 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) GHMP_kinases_N PF00288.26 KIY43057.1 - 5.6e-09 36.1 0.1 1.1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIY43057.1 - 0.0029 17.9 0.0 0.0085 16.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Cyclin_N PF00134.23 KIY43058.1 - 2.8e-11 43.3 0.3 1.1e-09 38.1 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Trefoil PF00088.18 KIY43062.1 - 0.058 13.3 0.9 0.096 12.6 0.1 1.8 2 0 0 2 2 2 0 Trefoil (P-type) domain DUF2025 PF09634.10 KIY43066.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) Ski2_N PF17911.1 KIY43066.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Ski2 N-terminal region F-box-like PF12937.7 KIY43069.1 - 0.0034 17.2 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like zf-CCHH PF10283.9 KIY43069.1 - 0.09 12.8 1.3 0.26 11.3 1.3 1.7 1 0 0 1 1 1 0 PBZ domain APH PF01636.23 KIY43072.1 - 5.3e-18 65.8 0.1 1.8e-17 64.0 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY43072.1 - 0.00025 20.5 0.1 0.0025 17.2 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KIY43072.1 - 0.011 14.6 0.0 0.1 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) CagS PF16707.5 KIY43073.1 - 0.042 13.9 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Kei1 PF08552.11 KIY43076.1 - 5.4e-57 192.8 1.9 7.2e-57 192.4 1.9 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 IF4E PF01652.18 KIY43077.1 - 3.3e-50 170.0 0.0 4.1e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mem_trans PF03547.18 KIY43078.1 - 2.9e-19 68.7 8.4 1.9e-18 66.1 8.4 1.9 1 1 0 1 1 1 1 Membrane transport protein F-box-like PF12937.7 KIY43080.1 - 9e-09 35.1 0.1 4.1e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY43080.1 - 0.013 15.3 0.1 0.17 11.8 0.1 2.9 2 1 0 2 2 2 0 F-box domain MIP-T3_C PF17749.1 KIY43080.1 - 0.2 11.6 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Med4 PF10018.9 KIY43081.1 - 3.4e-23 82.3 0.0 4.2e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Spectrin PF00435.21 KIY43081.1 - 0.0088 16.5 2.1 0.017 15.6 2.1 1.5 1 0 0 1 1 1 1 Spectrin repeat Cauli_AT PF03233.13 KIY43081.1 - 0.055 13.4 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Aphid transmission protein CENP-H PF05837.12 KIY43081.1 - 0.16 12.4 3.1 0.23 11.9 3.1 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.22 KIY43081.1 - 0.42 10.9 2.9 0.86 9.9 2.9 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MMS19_C PF12460.8 KIY43082.1 - 3.2e-105 352.7 1.2 3.2e-105 352.7 1.2 2.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KIY43082.1 - 4.5e-87 291.9 0.0 1.8e-83 280.1 0.0 3.2 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 KIY43082.1 - 0.00046 20.6 9.0 0.02 15.4 0.7 6.2 7 0 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 KIY43082.1 - 0.0006 20.1 13.5 0.34 11.3 0.4 6.7 7 1 0 8 8 7 2 HEAT repeats DUF3437 PF11919.8 KIY43082.1 - 0.0079 16.1 0.6 1.9 8.5 0.0 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) Tti2 PF10521.9 KIY43082.1 - 0.012 15.2 0.1 1.3 8.5 0.0 3.0 3 0 0 3 3 3 0 Tti2 family Adaptin_N PF01602.20 KIY43082.1 - 0.053 12.1 1.3 0.86 8.1 0.0 3.1 4 0 0 4 4 4 0 Adaptin N terminal region Arm PF00514.23 KIY43082.1 - 0.062 13.4 0.0 16 5.7 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FANCI_S2 PF14676.6 KIY43082.1 - 0.13 12.5 0.3 22 5.3 0.0 3.7 4 0 0 4 4 4 0 FANCI solenoid 2 HEAT PF02985.22 KIY43082.1 - 0.23 11.8 12.3 12 6.4 0.3 6.7 7 0 0 7 7 7 0 HEAT repeat Nipped-B_C PF12830.7 KIY43082.1 - 0.24 11.3 0.9 1.8 8.5 0.0 2.9 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus Voltage_CLC PF00654.20 KIY43083.1 - 1.4e-84 284.4 28.2 1.4e-84 284.4 28.2 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KIY43083.1 - 3.6e-08 33.7 1.8 0.0034 17.8 0.1 3.0 3 0 0 3 3 3 2 CBS domain Aldo_ket_red PF00248.21 KIY43084.1 - 2.1e-38 132.2 0.3 7e-25 87.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Flu_NS2 PF00601.19 KIY43085.1 - 0.095 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) p450 PF00067.22 KIY43086.1 - 2e-05 23.5 0.0 2e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydrolase_3 PF08282.12 KIY43087.1 - 0.00092 19.0 0.3 0.0011 18.8 0.3 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KIY43089.1 - 3.5e-25 88.7 45.1 1.7e-24 86.4 37.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY43089.1 - 0.023 14.0 24.9 0.043 13.1 24.9 1.4 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB ANTH PF07651.16 KIY43090.1 - 1e-48 165.7 0.2 1.7e-48 165.0 0.2 1.4 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KIY43090.1 - 0.035 14.2 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 ENTH domain F-box-like PF12937.7 KIY43091.1 - 1.5e-06 27.9 0.2 5.6e-06 26.2 0.2 2.1 1 0 0 1 1 1 1 F-box-like DUF1707 PF08044.11 KIY43092.1 - 0.074 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) DEC-1_N PF04625.13 KIY43092.1 - 0.22 10.5 9.4 0.35 9.8 9.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MFS_1 PF07690.16 KIY43094.1 - 1.3e-26 93.4 31.4 1.8e-26 92.9 31.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY43094.1 - 5.8e-05 21.7 4.6 0.00012 20.6 4.6 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM65 PF10507.9 KIY43094.1 - 0.046 13.7 1.1 0.17 11.9 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein 65 Epimerase PF01370.21 KIY43095.1 - 4.5e-11 42.7 0.1 2.1e-10 40.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY43095.1 - 3.1e-06 27.2 0.6 4.4e-06 26.7 0.6 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY43095.1 - 3.1e-05 23.1 0.1 0.00012 21.2 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIY43095.1 - 0.00025 20.2 0.0 0.0031 16.6 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIY43095.1 - 0.00067 18.9 0.1 0.0016 17.6 0.1 1.6 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 KIY43095.1 - 0.0012 18.8 0.2 0.0041 17.1 0.1 1.9 1 1 1 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KIY43095.1 - 0.003 17.8 0.2 0.0047 17.2 0.2 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KIY43095.1 - 0.012 15.0 0.1 0.036 13.5 0.1 1.8 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIY43095.1 - 0.015 14.8 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 KIY43095.1 - 0.062 13.4 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_28 PF02636.17 KIY43097.1 - 3.3e-34 118.7 0.0 4.5e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DSPc PF00782.20 KIY43098.1 - 3.3e-27 94.9 0.0 3.8e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY43098.1 - 0.00013 21.6 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIY43098.1 - 0.011 16.0 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain FGGY_C PF02782.16 KIY43099.1 - 7.8e-57 192.2 2.9 1.2e-56 191.6 2.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KIY43099.1 - 2.3e-54 184.5 0.0 3.2e-30 105.5 0.0 3.1 3 0 0 3 3 3 3 FGGY family of carbohydrate kinases, N-terminal domain Capsid_VP7 PF17071.5 KIY43099.1 - 0.035 13.4 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Outer capsid protein VP7 Tmemb_14 PF03647.13 KIY43100.1 - 2.6e-17 63.3 11.4 3.1e-17 63.1 11.4 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C p450 PF00067.22 KIY43101.1 - 5.5e-45 154.0 0.0 7e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BLM10_N PF16547.5 KIY43101.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal BBE PF08031.12 KIY43102.1 - 1.8e-06 28.0 0.8 3.3e-06 27.1 0.6 1.5 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 KIY43102.1 - 0.031 13.6 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding CdiI_4 PF18624.1 KIY43102.1 - 0.053 14.0 0.2 0.087 13.3 0.1 1.5 1 1 0 1 1 1 0 CDI immunity protein AAA PF00004.29 KIY43103.1 - 5.6e-41 140.0 0.0 8.9e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KIY43103.1 - 2.6e-28 97.8 0.2 6.5e-28 96.5 0.2 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KIY43103.1 - 7.8e-24 83.5 3.9 1.5e-23 82.6 3.9 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KIY43103.1 - 1.6e-07 31.0 0.0 6.6e-07 29.0 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KIY43103.1 - 8.1e-06 26.3 0.2 0.0003 21.2 0.1 2.6 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 KIY43103.1 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY43103.1 - 1e-05 25.5 0.0 2.6e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY43103.1 - 1.2e-05 25.6 0.9 0.017 15.4 0.1 2.6 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KIY43103.1 - 1.6e-05 24.7 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KIY43103.1 - 0.00018 21.5 0.0 0.00046 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KIY43103.1 - 0.00037 19.7 0.0 0.00061 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 KIY43103.1 - 0.0008 19.6 0.0 0.005 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KIY43103.1 - 0.0012 18.6 0.1 0.0047 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY43103.1 - 0.0018 18.5 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KIY43103.1 - 0.0024 17.1 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KIY43103.1 - 0.0033 18.0 0.0 0.0066 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIY43103.1 - 0.0051 17.2 0.0 0.013 15.8 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.6 KIY43103.1 - 0.011 15.3 0.5 0.72 9.4 0.1 2.7 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 KIY43103.1 - 0.024 14.0 0.1 4.3 6.6 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 KIY43103.1 - 0.029 13.9 0.3 0.23 10.9 0.0 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KIY43103.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KIY43103.1 - 0.039 14.0 0.0 0.89 9.7 0.0 2.2 2 0 0 2 2 2 0 Torsin AAA_17 PF13207.6 KIY43103.1 - 0.051 14.0 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIY43103.1 - 0.054 13.4 0.0 0.39 10.6 0.0 2.1 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 KIY43103.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TniB PF05621.11 KIY43103.1 - 0.065 12.6 0.0 3.3 7.1 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 KIY43103.1 - 0.084 12.6 0.0 0.34 10.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KIY43103.1 - 0.12 11.5 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.14 KIY43103.1 - 0.14 11.4 0.1 4.4 6.4 0.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 KIY43103.1 - 0.14 12.3 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain FAM150 PF15129.6 KIY43104.1 - 0.068 13.3 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 FAM150 family ATP-synt_ab PF00006.25 KIY43105.1 - 1.8e-73 246.7 0.0 2.8e-73 246.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KIY43105.1 - 1e-42 145.4 0.0 1.8e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KIY43105.1 - 1.6e-17 63.8 1.2 4e-17 62.5 1.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain G-alpha PF00503.20 KIY43106.1 - 3.9e-101 338.7 0.0 4.6e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY43106.1 - 1.9e-11 43.7 0.0 3.8e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KIY43106.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KIY43106.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY43106.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KIY43106.1 - 0.069 12.7 0.0 5 6.6 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain DAP3 PF10236.9 KIY43106.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Roc PF08477.13 KIY43106.1 - 0.19 12.0 0.0 4.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Lipase_3 PF01764.25 KIY43107.1 - 3.1e-14 53.0 0.0 1e-13 51.3 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KIY43107.1 - 0.025 13.8 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UvrD_C PF13361.6 KIY43108.1 - 2.6e-11 43.5 0.0 2.6e-07 30.4 0.0 3.6 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KIY43108.1 - 1.7e-08 34.3 5.5 7.9e-08 32.2 0.0 3.3 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KIY43108.1 - 9.7e-07 28.5 0.0 0.011 15.5 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KIY43108.1 - 4.9e-05 23.7 0.0 0.00049 20.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KIY43108.1 - 0.00059 19.5 0.6 0.045 13.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain TPR_7 PF13176.6 KIY43108.1 - 0.028 14.4 0.1 7.3 6.9 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.29 KIY43108.1 - 0.032 14.0 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY43108.1 - 0.048 13.9 0.1 0.67 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIY43108.1 - 0.12 12.1 0.1 45 3.7 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase IQ PF00612.27 KIY43108.1 - 0.12 12.2 11.9 0.45 10.4 2.7 2.9 1 1 1 2 2 2 0 IQ calmodulin-binding motif Cytochrom_B562 PF07361.11 KIY43108.1 - 0.17 12.5 3.6 0.67 10.6 3.6 2.0 1 0 0 1 1 1 0 Cytochrome b562 ABC_membrane PF00664.23 KIY43109.1 - 7.4e-68 229.2 27.7 6.5e-37 127.7 14.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY43109.1 - 2.1e-53 180.5 0.0 3.7e-31 108.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY43109.1 - 6.1e-09 35.6 0.5 0.019 14.4 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY43109.1 - 2.3e-05 24.9 0.9 0.025 14.9 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain DUF4574 PF15141.6 KIY43109.1 - 5.3e-05 23.1 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 AAA_29 PF13555.6 KIY43109.1 - 6.2e-05 22.6 0.4 0.027 14.2 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIY43109.1 - 6.5e-05 23.0 0.3 0.45 10.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KIY43109.1 - 0.003 18.1 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIY43109.1 - 0.0034 17.3 5.7 3.7 7.3 0.2 3.9 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 KIY43109.1 - 0.0037 16.3 0.1 2.2 7.2 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KIY43109.1 - 0.0039 17.3 4.4 0.084 13.0 0.1 2.7 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_30 PF13604.6 KIY43109.1 - 0.007 16.1 1.9 3.7 7.2 0.0 3.3 3 1 0 3 3 2 2 AAA domain T2SSE PF00437.20 KIY43109.1 - 0.0081 15.3 0.0 0.38 9.8 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein Dynamin_N PF00350.23 KIY43109.1 - 0.018 15.1 0.3 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.12 KIY43109.1 - 0.039 13.4 0.9 0.074 12.5 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 KIY43109.1 - 0.074 12.3 0.0 6.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KIY43109.1 - 0.077 12.6 0.0 8.9 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIY43109.1 - 0.09 12.7 0.9 14 5.6 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 KIY43109.1 - 0.11 12.4 0.8 16 5.4 0.1 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KIY43109.1 - 0.12 12.0 1.7 12 5.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 KIY43109.1 - 0.17 10.6 1.0 0.67 8.7 0.0 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 KIY43109.1 - 0.18 11.5 0.1 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIY43109.1 - 0.18 12.0 4.1 0.86 9.9 0.2 3.5 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY43109.1 - 0.25 10.7 0.7 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 KIY43109.1 - 0.34 10.0 4.9 3.3 6.8 0.0 3.3 3 1 0 3 3 3 0 NB-ARC domain S_4TM PF18159.1 KIY43109.1 - 2.2 7.5 10.5 1 8.6 0.4 3.3 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain Ribosomal_60s PF00428.19 KIY43110.1 - 2.9e-15 56.6 6.5 5.8e-13 49.3 6.5 2.1 1 1 0 1 1 1 1 60s Acidic ribosomal protein RibD_C PF01872.17 KIY43110.1 - 0.033 14.0 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 RibD C-terminal domain Dimer_Tnp_hAT PF05699.14 KIY43111.1 - 6.6e-12 45.1 0.0 1.8e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 KIY43113.1 - 5.9e-08 33.2 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY43113.1 - 0.00018 22.1 0.0 0.00036 21.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIY43113.1 - 0.00037 20.3 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotran_gag_2 PF14223.6 KIY43114.1 - 0.0098 15.6 0.5 0.013 15.2 0.5 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AhpC-TSA_2 PF13911.6 KIY43114.1 - 0.13 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme RRS1 PF04939.12 KIY43118.1 - 4.7e-10 39.6 0.0 5.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) F-box-like PF12937.7 KIY43119.1 - 1.4e-08 34.5 2.4 4e-08 33.0 0.1 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY43119.1 - 0.0032 17.3 1.3 0.027 14.3 1.3 2.6 1 1 0 1 1 1 1 F-box domain ABC_tran_CTD PF16326.5 KIY43119.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain NAP PF00956.18 KIY43119.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF2761 PF10959.8 KIY43120.1 - 0.023 14.7 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) MFS_1 PF07690.16 KIY43121.1 - 3.2e-39 134.9 45.2 4.4e-39 134.4 45.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY43121.1 - 5.5e-08 32.1 20.9 3.7e-06 26.1 20.9 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KIY43121.1 - 0.0019 16.7 3.3 0.0029 16.1 3.3 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Peptidase_C48 PF02902.19 KIY43125.1 - 4e-06 26.8 0.0 8.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain UVR PF02151.19 KIY43125.1 - 0.13 12.1 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 UvrB/uvrC motif Glyco_hydro_28 PF00295.17 KIY43128.1 - 2.9e-62 210.6 11.7 3.5e-62 210.3 11.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIY43128.1 - 8.4e-10 38.7 15.7 9.7e-10 38.5 13.1 2.3 2 2 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 KIY43128.1 - 1.1e-07 31.4 2.9 2.1e-07 30.5 2.9 1.5 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KIY43128.1 - 2e-05 24.1 1.7 3.3e-05 23.3 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1565) DUF4957 PF16318.5 KIY43128.1 - 0.1 12.6 5.4 0.21 11.5 3.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4957) Rab5ip PF07019.12 KIY43129.1 - 1.3e-18 67.3 4.8 1.6e-18 67.1 4.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) F-box-like PF12937.7 KIY43130.1 - 0.00061 19.6 4.1 0.00071 19.4 0.7 2.7 2 0 0 2 2 2 1 F-box-like PspA_IM30 PF04012.12 KIY43130.1 - 0.14 11.7 0.5 0.22 11.1 0.5 1.2 1 0 0 1 1 1 0 PspA/IM30 family Semialdhyde_dhC PF02774.18 KIY43131.1 - 3.7e-39 134.7 0.0 5.2e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KIY43131.1 - 3.6e-29 101.6 0.0 6e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KIY43131.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KIY43131.1 - 0.088 13.5 0.1 0.2 12.3 0.0 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Amidase PF01425.21 KIY43132.1 - 8.2e-85 285.4 0.0 1.5e-84 284.6 0.0 1.4 1 1 0 1 1 1 1 Amidase FmiP_Thoc5 PF09766.9 KIY43136.1 - 0.096 12.0 1.5 0.14 11.5 1.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 TRI5 PF06330.11 KIY43137.1 - 2e-09 36.8 0.2 2.4e-09 36.5 0.2 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) HNH_2 PF13391.6 KIY43139.1 - 0.017 15.2 0.8 0.14 12.3 0.0 2.9 4 0 0 4 4 4 0 HNH endonuclease Methyltransf_2 PF00891.18 KIY43141.1 - 2.1e-20 72.9 0.0 2.4e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain MarR_2 PF12802.7 KIY43141.1 - 0.0018 18.2 0.0 0.0086 15.9 0.0 2.2 2 0 0 2 2 2 1 MarR family Dimerisation2 PF16864.5 KIY43141.1 - 0.0035 17.3 0.0 0.027 14.5 0.0 2.2 2 0 0 2 2 2 1 Dimerisation domain HTH_IclR PF09339.10 KIY43141.1 - 0.0054 16.5 0.0 0.02 14.7 0.0 2.0 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 KIY43141.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Methyltransf_12 PF08242.12 KIY43141.1 - 0.08 13.7 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FAT PF02259.23 KIY43142.1 - 0.45 9.7 4.7 0.1 11.8 0.6 1.9 2 1 0 2 2 2 0 FAT domain Cu_amine_oxid PF01179.20 KIY43143.1 - 5.1e-120 401.1 0.1 7e-120 400.7 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KIY43143.1 - 1.8e-08 34.0 0.3 5.9e-08 32.4 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KIY43143.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain VSP PF03302.13 KIY43144.1 - 0.081 11.8 5.4 0.06 12.2 0.6 2.1 2 0 0 2 2 2 0 Giardia variant-specific surface protein Podoplanin PF05808.11 KIY43144.1 - 1.5 8.9 8.0 0.42 10.7 1.4 2.3 2 0 0 2 2 2 0 Podoplanin APH PF01636.23 KIY43145.1 - 1.7e-06 28.1 0.0 0.0002 21.4 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KIY43145.1 - 0.0071 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY43145.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIY43145.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase SDA1 PF05285.12 KIY43149.1 - 0.00013 21.5 16.2 0.00015 21.3 16.2 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 KIY43149.1 - 0.0075 14.6 13.4 0.0089 14.4 13.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 KIY43149.1 - 0.21 9.7 26.2 0.27 9.4 26.2 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 KIY43149.1 - 1.6 7.4 7.5 2 7.1 7.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 KIY43149.1 - 2.8 6.3 25.8 3.9 5.8 25.8 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 KIY43149.1 - 8.2 5.7 31.8 11 5.2 31.8 1.1 1 0 0 1 1 1 0 BUD22 Cullin PF00888.22 KIY43151.1 - 2.3e-182 607.9 16.1 2.3e-182 607.9 16.1 1.4 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIY43151.1 - 2.6e-26 91.4 3.6 1.2e-25 89.2 3.6 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_27 PF13463.6 KIY43151.1 - 0.019 15.5 0.8 4.9 7.7 0.0 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain HSCB_C PF07743.13 KIY43151.1 - 0.13 12.8 7.2 0.42 11.1 0.2 3.7 2 2 0 2 2 2 0 HSCB C-terminal oligomerisation domain Penicillinase_R PF03965.16 KIY43151.1 - 1.2 9.5 11.0 0.34 11.3 0.3 4.2 4 0 0 4 4 4 0 Penicillinase repressor DUF1768 PF08719.11 KIY43152.1 - 4e-16 59.7 0.0 4.9e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) TRI5 PF06330.11 KIY43153.1 - 2.5e-10 39.8 0.3 2.9e-10 39.6 0.3 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) RRM_3 PF08777.11 KIY43154.1 - 9.6e-12 44.9 0.0 7.6e-06 25.9 0.0 3.8 2 1 0 2 2 2 2 RNA binding motif RRM_1 PF00076.22 KIY43154.1 - 0.0068 16.2 0.0 11 5.9 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L4 PF00573.22 KIY43154.1 - 0.094 12.4 0.4 11 5.7 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein L4/L1 family 4HBT PF03061.22 KIY43155.1 - 0.0001 22.6 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily GIDA PF01134.22 KIY43156.1 - 6.7e-149 496.2 0.0 8e-149 496.0 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KIY43156.1 - 3.3e-65 220.2 0.0 6.4e-65 219.3 0.0 1.5 2 0 0 2 2 2 1 GidA associated domain FAD_oxidored PF12831.7 KIY43156.1 - 1.9e-06 27.5 0.5 4.6e-06 26.3 0.5 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY43156.1 - 3.2e-05 23.3 3.9 0.00036 19.9 2.2 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY43156.1 - 0.0019 17.4 2.2 0.0037 16.4 2.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIY43156.1 - 0.0029 16.4 1.2 0.18 10.5 0.6 2.4 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KIY43156.1 - 0.0033 16.7 0.2 0.0066 15.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KIY43156.1 - 0.02 14.5 0.6 1.7 8.2 0.5 2.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIY43156.1 - 0.04 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY43156.1 - 0.043 14.4 0.3 0.1 13.2 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3602 PF12223.8 KIY43157.1 - 9.5e-18 64.6 20.7 1.1e-08 35.6 4.2 5.0 1 1 4 5 5 5 5 Protein of unknown function (DUF3602) PNPase_C PF12111.8 KIY43157.1 - 1.4 8.4 4.5 1.6 8.2 0.1 2.6 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal 4HBT PF03061.22 KIY43159.1 - 2.2e-08 34.4 0.0 3.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KIY43159.1 - 0.016 15.4 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily PH PF00169.29 KIY43160.1 - 1.5e-12 47.9 0.3 3.3e-12 46.8 0.3 1.6 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 KIY43160.1 - 1.6e-11 43.8 1.3 3e-08 33.4 0.4 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KIY43160.1 - 2.5e-10 39.8 2.7 7.2e-10 38.3 0.5 2.7 3 0 0 3 3 3 1 SH3 domain SAM_1 PF00536.30 KIY43160.1 - 3.5e-10 40.2 0.0 7.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KIY43160.1 - 7.1e-10 38.9 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KIY43160.1 - 4.5e-05 23.0 0.7 0.00022 20.9 0.1 2.3 2 1 0 2 2 2 1 Variant SH3 domain SAM_3 PF18016.1 KIY43160.1 - 0.00096 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KIY43160.1 - 0.11 12.8 0.2 0.22 11.8 0.2 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Phage_integrase PF00589.22 KIY43164.1 - 0.0024 17.7 0.0 0.0051 16.6 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Sulfatase_C PF14707.6 KIY43165.1 - 0.18 12.5 0.5 5.4 7.8 0.1 2.2 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase Pro_isomerase PF00160.21 KIY43166.1 - 5.3e-37 127.5 0.0 8.4e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KIY43166.1 - 9e-16 57.5 0.0 1.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OPT PF03169.15 KIY43167.1 - 0.00012 20.9 0.6 0.00013 20.8 0.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TPR_6 PF13174.6 KIY43167.1 - 0.13 13.0 0.4 1.3 9.9 0.4 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat Hist_deacetyl PF00850.19 KIY43168.1 - 4e-23 82.4 0.4 5e-23 82.0 0.4 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Nucleo_P87 PF07267.11 KIY43171.1 - 0.62 8.8 11.2 1.2 7.9 11.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Tet_JBP PF12851.7 KIY43172.1 - 0.0083 15.5 0.0 0.0098 15.3 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Acyl_transf_1 PF00698.21 KIY43173.1 - 4.4e-06 26.4 0.0 4.8e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain Plavaka PF18759.1 KIY43174.1 - 1.3e-19 70.6 0.2 1.7e-19 70.2 0.2 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY43175.1 - 7.5e-63 212.7 0.1 8.3e-63 212.6 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase Co_AT_N PF12557.8 KIY43175.1 - 0.012 15.5 0.4 0.027 14.4 0.4 1.6 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal DAGK_cat PF00781.24 KIY43175.1 - 0.095 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Plavaka PF18759.1 KIY43176.1 - 1.8e-13 50.4 0.0 3.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase DUF3960 PF13142.6 KIY43176.1 - 0.025 14.7 0.0 0.41 10.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3960) ENTH PF01417.20 KIY43182.1 - 2.4e-51 173.0 0.1 5.8e-51 171.8 0.1 1.7 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 KIY43182.1 - 0.00019 21.1 11.4 0.03 14.3 1.6 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif ArfGap PF01412.18 KIY43184.1 - 9.5e-39 132.1 0.3 1e-38 132.0 0.3 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_M1 PF01433.20 KIY43185.1 - 1.1e-32 113.4 0.1 1.7e-32 112.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KIY43185.1 - 1.3e-30 105.8 0.0 2.3e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KIY43185.1 - 2.8e-17 63.5 0.0 4.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M64 PF09471.10 KIY43185.1 - 0.044 13.3 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M24 PF00557.24 KIY43186.1 - 2.3e-55 187.5 0.0 2.9e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KIY43186.1 - 9.5e-20 70.6 0.0 1.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain ASXH PF13919.6 KIY43187.1 - 6.5e-22 78.0 0.3 9.9e-22 77.5 0.3 1.2 1 0 0 1 1 1 1 Asx homology domain zf-C2H2 PF00096.26 KIY43188.1 - 1.2e-08 34.9 17.5 0.00095 19.5 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY43188.1 - 2.7e-08 33.9 14.9 0.0028 18.3 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY43188.1 - 0.00094 19.4 6.3 0.058 13.7 0.3 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY43188.1 - 0.013 15.8 4.5 0.13 12.7 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type RGS12_us1 PF16613.5 KIY43188.1 - 0.022 15.1 3.5 0.022 15.1 3.5 1.7 2 0 0 2 2 2 0 Unstructured region of RGS12 zf-C2H2_11 PF16622.5 KIY43188.1 - 0.026 14.3 10.0 0.49 10.2 0.4 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KIY43188.1 - 0.54 10.3 0.2 0.54 10.3 0.2 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger GTP_EFTU PF00009.27 KIY43189.1 - 5.6e-60 202.2 0.1 9.2e-60 201.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIY43189.1 - 5.4e-40 135.9 0.2 5.2e-39 132.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 KIY43189.1 - 4.9e-28 97.0 0.0 9.9e-28 96.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KIY43189.1 - 2.4e-17 62.7 0.0 6.4e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIY43189.1 - 5.9e-11 42.6 0.0 2.4e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KIY43189.1 - 3.3e-05 23.7 0.0 6.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Gluconate_2-dh3 PF13618.6 KIY43189.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Ribonuc_red_sm PF00268.21 KIY43191.1 - 1.3e-110 369.3 0.2 1.5e-110 369.1 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HA2 PF04408.23 KIY43192.1 - 2.3e-08 34.3 0.0 3.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY43192.1 - 3.8e-07 30.4 0.2 7.3e-06 26.3 0.2 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY43192.1 - 0.0047 16.7 0.1 0.0078 16.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KIY43193.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KIY43193.1 - 0.027 13.5 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Type_ISP_C PF18135.1 KIY43193.1 - 0.045 12.7 0.1 0.045 12.7 0.1 1.0 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain ABC_tran PF00005.27 KIY43193.1 - 0.055 14.0 0.3 0.096 13.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter DEAD PF00270.29 KIY43193.1 - 0.055 13.2 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_33 PF13671.6 KIY43193.1 - 0.072 13.3 0.2 2.1 8.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIY43193.1 - 0.092 12.5 1.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY43193.1 - 0.13 12.6 0.5 0.31 11.3 0.2 1.7 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 KIY43193.1 - 0.16 12.4 0.6 0.24 11.9 0.4 1.5 1 1 0 1 1 1 0 AAA domain LRR_4 PF12799.7 KIY43194.1 - 0.023 15.1 3.6 10 6.7 1.4 4.6 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) DUF4604 PF15377.6 KIY43194.1 - 0.058 13.8 1.9 0.11 13.0 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) HA2 PF04408.23 KIY43195.1 - 2.3e-23 82.5 0.3 7.4e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY43195.1 - 1.6e-20 73.3 0.0 4.8e-20 71.7 0.0 1.8 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY43195.1 - 2.4e-10 40.8 0.0 9.5e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SRP54 PF00448.22 KIY43195.1 - 0.0029 17.3 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KIY43195.1 - 0.0074 16.6 0.0 0.026 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KIY43195.1 - 0.01 15.2 0.3 0.023 14.0 0.0 1.7 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 KIY43195.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 KIY43195.1 - 0.03 14.7 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIY43195.1 - 0.03 13.9 0.0 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KIY43195.1 - 0.031 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIY43195.1 - 0.087 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Proteasome PF00227.26 KIY43196.1 - 1.5e-29 102.9 0.0 1.8e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.17 KIY43196.1 - 0.13 12.2 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain RNase_PH PF01138.21 KIY43198.1 - 8.1e-12 45.8 0.0 1.5e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 AMP-binding PF00501.28 KIY43199.1 - 3.1e-28 98.6 0.1 2.3e-27 95.6 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIY43199.1 - 3.4e-21 75.6 0.0 5.2e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KIY43199.1 - 5.5e-06 26.6 0.0 1.5e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KIY43199.1 - 2.6e-05 23.8 0.0 5.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CBF PF03914.17 KIY43200.1 - 1.1e-40 139.5 0.2 6.6e-40 136.9 0.0 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Methyltransf_31 PF13847.6 KIY43201.1 - 4.9e-29 101.1 0.0 7.2e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY43201.1 - 2.3e-24 85.9 0.0 5.4e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY43201.1 - 1.3e-22 80.3 0.0 2.8e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY43201.1 - 9.9e-18 64.5 0.0 1.7e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY43201.1 - 1.9e-17 63.4 0.0 2.6e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KIY43201.1 - 5.9e-14 52.6 0.0 9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIY43201.1 - 5e-10 39.3 0.0 7.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KIY43201.1 - 2.4e-08 34.0 0.0 3.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 KIY43201.1 - 2.6e-06 26.3 0.0 3.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KIY43201.1 - 1.4e-05 24.7 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KIY43201.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 KIY43201.1 - 0.00028 19.9 0.0 0.00045 19.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 KIY43201.1 - 0.00028 20.4 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.12 KIY43201.1 - 0.0038 16.4 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_2 PF00891.18 KIY43201.1 - 0.018 14.3 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PAS_3 PF08447.12 KIY43201.1 - 0.03 14.6 0.0 0.7 10.2 0.0 2.3 2 0 0 2 2 2 0 PAS fold TehB PF03848.14 KIY43201.1 - 0.037 13.4 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 KIY43201.1 - 0.046 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KIY43201.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 KIY43201.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 KIY43201.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PCI PF01399.27 KIY43202.1 - 6.7e-09 36.2 0.1 1e-06 29.2 0.0 2.7 2 0 0 2 2 2 2 PCI domain cobW PF02492.19 KIY43203.1 - 5.6e-32 110.7 0.0 6.7e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KIY43203.1 - 0.00087 18.3 0.0 0.061 12.3 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TIP49 PF06068.13 KIY43203.1 - 0.0034 16.7 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain MMR_HSR1 PF01926.23 KIY43203.1 - 0.0052 16.9 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 KIY43203.1 - 0.015 15.4 0.0 0.031 14.3 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KIY43203.1 - 0.024 15.2 0.0 0.045 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIY43203.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KIY43203.1 - 0.033 14.2 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KIY43203.1 - 0.034 14.6 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KIY43203.1 - 0.067 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KIY43203.1 - 0.073 13.6 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KIY43203.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KIY43203.1 - 0.1 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 KIY43203.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ResIII PF04851.15 KIY43203.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PRK PF00485.18 KIY43203.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 KIY43203.1 - 0.16 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KIY43203.1 - 0.16 12.2 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KIY43203.1 - 0.24 10.8 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein SelP_N PF04592.14 KIY43203.1 - 9.2 5.6 13.6 13 5.1 13.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PIN_4 PF13638.6 KIY43204.1 - 1e-06 29.0 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 PIN domain OTCace_N PF02729.21 KIY43205.1 - 7.6e-42 142.8 0.0 1.2e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KIY43205.1 - 1.2e-39 135.9 0.0 1.7e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain AMP-binding PF00501.28 KIY43206.1 - 2e-24 86.0 0.0 2.6e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIY43206.1 - 1.3e-20 73.7 0.0 2.1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KIY43206.1 - 1.2e-06 28.8 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KIY43206.1 - 0.0014 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FHA PF00498.26 KIY43207.1 - 5e-11 42.8 0.0 7.3e-08 32.7 0.0 2.8 3 0 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 KIY43207.1 - 0.0076 16.5 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF2283 PF10049.9 KIY43207.1 - 0.082 13.2 0.3 15 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) Pkinase PF00069.25 KIY43208.1 - 1.9e-68 230.7 0.0 2.2e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43208.1 - 2.7e-30 105.5 0.0 3.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY43208.1 - 0.00017 20.7 0.2 0.0018 17.3 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY43208.1 - 0.005 16.8 0.1 0.02 14.8 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY43208.1 - 0.017 14.5 0.1 0.22 10.8 0.0 2.1 1 1 0 2 2 2 0 Kinase-like PDH PF02153.17 KIY43209.1 - 3.9e-11 42.5 0.0 5.4e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KIY43209.1 - 1.5e-06 28.4 0.0 2.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIY43209.1 - 1.5e-05 25.4 0.0 3.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KIY43209.1 - 0.0025 17.9 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KIY43209.1 - 0.0075 15.9 0.0 0.085 12.5 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KIY43209.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 KIY43209.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIY43209.1 - 0.046 13.7 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PPR_2 PF13041.6 KIY43210.1 - 1.1e-09 38.3 0.0 0.0037 17.4 0.0 4.6 4 1 1 5 5 5 4 PPR repeat family PPR_1 PF12854.7 KIY43210.1 - 1.1e-06 28.2 0.0 0.0013 18.4 0.0 4.3 4 0 0 4 4 4 1 PPR repeat PPR PF01535.20 KIY43210.1 - 2.7e-06 27.2 2.3 0.09 13.1 0.1 5.6 4 2 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KIY43210.1 - 0.00043 20.3 0.0 1.1 9.4 0.0 3.3 3 0 0 3 3 3 2 Pentatricopeptide repeat domain Bac_surface_Ag PF01103.23 KIY43211.1 - 1.9e-39 136.0 0.8 2.4e-39 135.8 0.8 1.1 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 KIY43211.1 - 0.00045 19.8 0.0 0.00094 18.7 0.0 1.6 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA PF07244.15 KIY43211.1 - 0.061 13.9 0.0 0.18 12.4 0.0 1.8 2 0 0 2 2 2 0 Surface antigen variable number repeat DUF1515 PF07439.11 KIY43215.1 - 0.065 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4054 PF13262.6 KIY43215.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Sigma70_ner PF04546.13 KIY43216.1 - 0.021 14.7 1.4 0.021 14.7 1.4 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Serglycin PF04360.12 KIY43216.1 - 0.2 11.6 1.7 0.32 10.9 1.7 1.3 1 0 0 1 1 1 0 Serglycin Fungal_trans_2 PF11951.8 KIY43217.1 - 5e-06 25.6 3.2 0.0087 14.9 0.0 3.0 1 1 2 3 3 3 3 Fungal specific transcription factor domain Transket_pyr PF02779.24 KIY43218.1 - 8e-64 214.6 0.0 1.3e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KIY43218.1 - 6e-61 206.0 0.0 8.6e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KIY43218.1 - 7.4e-52 175.1 0.0 1.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KIY43218.1 - 2e-17 62.5 0.3 3.7e-17 61.6 0.3 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus DUF2347 PF09804.9 KIY43221.1 - 6.6e-45 153.9 0.0 9.1e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 KIY43221.1 - 1.9e-08 33.5 0.0 0.014 14.2 0.1 3.1 3 0 0 3 3 3 3 Transport protein Avl9 Inositol_P PF00459.25 KIY43222.1 - 3.4e-49 167.8 0.0 1.3e-48 165.9 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family WSC PF01822.19 KIY43224.1 - 1.9e-45 152.9 54.2 4.6e-19 68.4 16.0 5.9 5 1 1 6 6 6 5 WSC domain Glyoxal_oxid_N PF07250.11 KIY43224.1 - 2.4e-29 102.2 0.0 6.4e-28 97.6 0.0 2.4 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIY43224.1 - 1.5e-21 76.4 0.0 4.9e-21 74.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 KIY43224.1 - 0.31 11.1 3.4 0.82 9.8 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Gti1_Pac2 PF09729.9 KIY43225.1 - 1.8e-56 191.1 0.1 4.1e-56 189.9 0.1 1.6 1 1 0 1 1 1 1 Gti1/Pac2 family Glyco_trans_2_3 PF13632.6 KIY43226.1 - 4.2e-59 199.8 0.7 4.2e-59 199.8 0.7 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIY43226.1 - 8.5e-05 22.6 0.1 0.00021 21.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIY43226.1 - 0.00071 19.4 0.0 0.0069 16.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIY43226.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF3925 PF13063.6 KIY43226.1 - 0.063 13.5 1.0 0.23 11.7 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Glyco_hydro_16 PF00722.21 KIY43228.1 - 2.1e-18 66.4 0.6 3.3e-18 65.8 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PI-PLC-X PF00388.19 KIY43229.1 - 2.8e-42 143.7 0.0 4.4e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIY43229.1 - 2.5e-32 111.6 0.0 5.4e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KIY43229.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 C2 domain motB PF17613.2 KIY43229.1 - 0.057 13.3 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Modifier of transcription PG_binding_2 PF08823.11 KIY43229.1 - 0.062 13.6 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain RP-C_C PF11800.8 KIY43230.1 - 0.16 12.0 6.0 0.21 11.7 1.3 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region JAKMIP_CC3 PF16034.5 KIY43230.1 - 0.31 11.0 12.4 1.8 8.5 4.2 2.4 2 0 0 2 2 2 0 JAKMIP CC3 domain DUF4834 PF16118.5 KIY43230.1 - 0.99 10.4 4.1 0.71 10.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 KIY43230.1 - 1.7 7.3 5.2 0.23 10.2 1.0 1.6 2 0 0 2 2 2 0 Presenilin SOG2 PF10428.9 KIY43230.1 - 2 7.5 11.1 0.57 9.3 8.0 1.5 1 1 0 2 2 2 0 RAM signalling pathway protein FHA PF00498.26 KIY43231.1 - 2.3e-09 37.5 0.1 4.5e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 FHA domain EzrA PF06160.12 KIY43231.1 - 0.013 13.7 1.0 0.024 12.8 0.6 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 KIY43231.1 - 0.026 14.1 1.2 0.043 13.4 0.0 1.9 3 0 0 3 3 3 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KIY43231.1 - 0.056 13.5 5.6 0.12 12.4 2.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Snf7 PF03357.21 KIY43231.1 - 0.06 13.0 0.9 0.085 12.4 0.0 1.6 2 0 0 2 2 2 0 Snf7 UPF0242 PF06785.11 KIY43231.1 - 0.14 12.3 0.5 0.33 11.1 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 KIY43231.1 - 0.14 12.6 0.2 5.1 7.6 0.0 3.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FAM76 PF16046.5 KIY43231.1 - 0.15 11.4 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 FAM76 protein BLOC1_2 PF10046.9 KIY43231.1 - 0.18 12.1 1.1 23 5.4 0.0 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HOOK PF05622.12 KIY43231.1 - 0.36 8.9 5.6 2.5 6.1 2.4 2.1 2 0 0 2 2 2 0 HOOK protein XhlA PF10779.9 KIY43231.1 - 3 8.1 6.3 37 4.6 0.2 3.9 4 1 1 5 5 5 0 Haemolysin XhlA Es2 PF09751.9 KIY43232.1 - 0.00083 19.2 0.2 0.00083 19.2 0.2 2.2 3 0 0 3 3 3 1 Nuclear protein Es2 Peptidase_C10 PF01640.17 KIY43232.1 - 2 8.7 5.6 0.67 10.2 2.5 1.8 2 0 0 2 2 2 0 Peptidase C10 family Importin_rep_4 PF18808.1 KIY43233.1 - 1.3e-15 57.5 0.2 5.9e-15 55.3 0.1 2.2 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 KIY43233.1 - 3.3e-15 56.2 10.5 1.1e-05 25.8 0.0 7.8 6 1 2 8 8 8 3 HEAT-like repeat HEAT PF02985.22 KIY43233.1 - 4.6e-14 51.3 5.1 0.00016 21.6 0.0 7.3 8 0 0 8 8 7 3 HEAT repeat HEAT_2 PF13646.6 KIY43233.1 - 9.2e-13 48.4 6.6 0.00018 21.8 0.0 7.0 3 2 4 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KIY43233.1 - 4.7e-11 43.1 0.0 3.1e-07 30.9 0.0 4.2 2 2 3 5 5 3 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KIY43233.1 - 1.2e-06 28.6 0.2 0.071 13.0 0.0 4.8 3 2 1 5 5 5 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KIY43233.1 - 2.9e-06 27.4 0.0 3.4e-05 23.9 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KIY43233.1 - 1.8e-05 24.5 3.3 0.026 14.3 0.0 4.6 3 1 0 4 4 4 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 KIY43233.1 - 3.4e-05 23.1 1.0 0.0028 16.8 0.1 3.0 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 KIY43233.1 - 0.00015 20.4 0.1 0.00052 18.7 0.0 1.9 2 0 0 2 2 2 1 Adaptin N terminal region Tti2 PF10521.9 KIY43233.1 - 0.0062 16.1 0.3 2.9 7.4 0.0 3.4 2 1 1 3 3 3 1 Tti2 family RTP1_C1 PF10363.9 KIY43233.1 - 0.012 15.8 0.0 1.4 9.1 0.0 3.6 3 2 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 KIY43233.1 - 0.033 13.9 2.8 4.6 6.9 0.0 4.1 5 1 1 6 6 6 0 Domain of unknown function (DUF4042) Cnd3 PF12719.7 KIY43233.1 - 0.081 12.1 0.2 2.2 7.4 0.0 2.9 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain UPF0561 PF10573.9 KIY43236.1 - 3.7 7.7 5.7 1.4 9.0 2.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 OPT PF03169.15 KIY43237.1 - 9.7e-178 592.6 55.6 8.5e-176 586.2 55.6 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Sugar_tr PF00083.24 KIY43238.1 - 1.6e-46 159.1 26.1 6.2e-45 153.9 26.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY43238.1 - 1.8e-20 73.2 50.6 8.1e-18 64.5 32.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1634 PF07843.11 KIY43238.1 - 0.018 15.1 0.7 0.11 12.6 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) DMT_YdcZ PF04657.13 KIY43238.1 - 6.8 7.0 19.4 0.16 12.2 3.9 3.8 4 0 0 4 4 4 0 Putative inner membrane exporter, YdcZ DUF5627 PF18620.1 KIY43239.1 - 0.43 10.4 7.4 0.087 12.7 2.8 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5627) Glyco_hydro_18 PF00704.28 KIY43240.1 - 6.1e-19 68.9 0.0 7.9e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AMP-binding PF00501.28 KIY43241.1 - 4.3e-27 94.8 0.3 7.4e-26 90.7 0.3 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIY43241.1 - 2.9e-26 92.2 0.0 4.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY43241.1 - 8.6e-07 28.7 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY43241.1 - 3e-05 24.3 0.0 0.0001 22.6 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 KIY43241.1 - 0.068 12.3 0.0 0.55 9.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIY43242.1 - 4.7e-15 55.4 0.0 7.4e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KIY43242.1 - 1.6e-05 25.2 0.0 5.1e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 KIY43242.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIY43242.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KIY43242.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SAC3_GANP PF03399.16 KIY43244.1 - 7.8e-49 166.6 1.9 1.2e-48 166.0 1.9 1.2 1 0 0 1 1 1 1 SAC3/GANP family ComX PF05952.12 KIY43245.1 - 0.048 13.6 0.5 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 Bacillus competence pheromone ComX UIM PF02809.20 KIY43246.1 - 0.02 14.8 0.8 0.02 14.8 0.8 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif DENN PF02141.21 KIY43246.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 DENN (AEX-3) domain Tri3 PF07428.11 KIY43247.1 - 0.044 12.7 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 adh_short PF00106.25 KIY43248.1 - 1.7e-10 40.7 1.5 3.1e-10 39.8 1.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY43248.1 - 2.2e-08 33.9 0.6 3.8e-08 33.2 0.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UIM PF02809.20 KIY43248.1 - 2.2e-05 24.1 19.5 0.00042 20.0 2.4 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif KR PF08659.10 KIY43248.1 - 0.00079 19.4 0.2 0.0015 18.5 0.2 1.4 1 0 0 1 1 1 1 KR domain SSDP PF04503.13 KIY43248.1 - 0.011 16.1 2.1 0.016 15.5 2.1 1.2 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP Eno-Rase_NADH_b PF12242.8 KIY43248.1 - 0.041 13.6 2.0 0.12 12.1 2.0 1.8 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NERD PF08378.11 KIY43248.1 - 0.07 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Nuclease-related domain DEAD PF00270.29 KIY43249.1 - 5.9e-12 45.7 0.0 7.4e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY43249.1 - 0.0037 17.3 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY43250.1 - 2.2e-11 43.8 0.0 2.9e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY43250.1 - 0.00057 19.9 0.0 0.0013 18.8 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NAD-GH PF10712.9 KIY43251.1 - 0.051 12.0 0.0 0.063 11.7 0.0 1.1 1 0 0 1 1 1 0 NAD-specific glutamate dehydrogenase tRNA-synt_1b PF00579.25 KIY43254.1 - 1.5e-65 221.5 0.0 2.8e-65 220.6 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Retrotrans_gag PF03732.17 KIY43255.1 - 4.8e-05 23.5 0.9 8.3e-05 22.8 0.4 1.7 1 1 1 2 2 2 1 Retrotransposon gag protein HSP70 PF00012.20 KIY43257.1 - 8.2e-83 278.6 0.3 9.6e-83 278.4 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY43257.1 - 1.2e-11 44.1 0.1 1.5e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 KIY43257.1 - 0.00012 21.1 0.3 0.012 14.6 0.2 2.2 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KIY43257.1 - 0.014 14.7 0.3 0.092 12.0 0.2 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 KIY43257.1 - 0.03 13.5 0.3 0.33 10.2 0.1 1.9 1 1 1 2 2 2 0 StbA protein DUF934 PF06073.12 KIY43257.1 - 0.15 11.9 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) PIF1 PF05970.14 KIY43258.1 - 1.5e-11 44.1 0.4 1.8e-06 27.3 0.4 3.1 1 1 1 3 3 3 3 PIF1-like helicase AAA_19 PF13245.6 KIY43258.1 - 0.0002 21.7 0.0 0.00025 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY43258.1 - 0.00023 21.0 0.1 0.00035 20.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain Retrotran_gag_2 PF14223.6 KIY43260.1 - 2.3e-16 59.7 0.2 2.6e-16 59.5 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ATP12 PF07542.11 KIY43260.1 - 0.017 15.2 0.4 0.18 11.9 0.1 2.3 2 1 0 2 2 2 0 ATP12 chaperone protein DUF668 PF05003.12 KIY43260.1 - 0.093 13.2 0.1 1.8 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF668) UBM PF14377.6 KIY43261.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Zn_clus PF00172.18 KIY43263.1 - 0.079 13.1 11.6 0.75 10.0 4.9 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain gag-asp_proteas PF13975.6 KIY43264.1 - 2.2e-08 34.6 0.0 3.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY43264.1 - 9.7e-06 26.1 0.0 1.8e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIY43264.1 - 0.0037 17.0 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Metallopep PF12044.8 KIY43268.1 - 2.7e-26 92.1 0.0 7e-17 61.1 0.0 3.3 2 1 1 3 3 3 3 Putative peptidase family Peptidase_A4 PF01828.17 KIY43268.1 - 0.13 11.8 0.4 0.26 10.7 0.4 1.4 1 0 0 1 1 1 0 Peptidase A4 family DDE_1 PF03184.19 KIY43269.1 - 2.6e-16 59.8 0.0 6.5e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4429 PF14472.6 KIY43269.1 - 0.073 13.7 0.2 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4429) Jak1_Phl PF17887.1 KIY43269.1 - 0.26 11.3 8.5 0.24 11.4 4.8 2.4 1 1 1 2 2 2 0 Jak1 pleckstrin homology-like domain Helicase_C PF00271.31 KIY43270.1 - 3e-19 69.4 0.0 1.4e-18 67.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY43270.1 - 1.9e-15 57.1 0.0 1e-14 54.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY43270.1 - 5.9e-06 26.4 0.0 9.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HK PF02110.15 KIY43272.1 - 1.1e-77 260.8 0.3 2.7e-77 259.5 0.3 1.6 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KIY43272.1 - 2.5e-39 134.5 0.7 2.6e-32 111.6 0.0 2.3 1 1 1 2 2 2 2 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KIY43272.1 - 3.8e-05 23.2 0.0 7.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PhyH PF05721.13 KIY43273.1 - 1.4e-31 110.4 0.0 1.2e-14 55.1 0.0 2.3 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) MOZ_SAS PF01853.18 KIY43274.1 - 1.5e-80 269.1 0.5 2.1e-80 268.6 0.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KIY43274.1 - 6.4e-25 86.5 0.9 1.3e-24 85.5 0.9 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KIY43274.1 - 4.1e-17 61.8 0.0 8.5e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KIY43274.1 - 0.0012 19.2 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY43274.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF2892 PF11127.8 KIY43275.1 - 8.7 6.5 6.3 23 5.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Rap1-DNA-bind PF09197.10 KIY43276.1 - 0.0029 18.2 2.4 0.01 16.4 0.2 2.1 1 1 1 2 2 2 1 Rap1, DNA-binding BRCT_2 PF16589.5 KIY43277.1 - 2.5e-07 31.0 0.0 3.2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KIY43277.1 - 0.0045 17.2 0.0 0.0067 16.7 0.0 1.2 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Put_Phosphatase PF06888.12 KIY43278.1 - 2e-48 164.9 0.0 2.4e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KIY43278.1 - 3.3e-05 24.4 0.0 5.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 5_nucleotid PF05761.14 KIY43278.1 - 0.049 12.5 0.1 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 5' nucleotidase family Med25_VWA PF11265.8 KIY43279.1 - 6e-12 45.8 0.0 6.7e-11 42.4 0.0 2.4 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A TFIIA PF03153.13 KIY43279.1 - 8.9e-06 25.9 45.1 8.9e-06 25.9 45.1 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 KIY43279.1 - 0.1 11.6 25.3 0.2 10.6 25.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AbLIM_anchor PF16182.5 KIY43279.1 - 0.13 12.1 11.7 0.22 11.3 11.7 1.3 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM FAM91_C PF14648.6 KIY43279.1 - 0.26 10.1 9.8 0.41 9.4 9.8 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Mem_trans PF03547.18 KIY43279.1 - 0.56 8.6 6.6 0.89 7.9 6.6 1.2 1 0 0 1 1 1 0 Membrane transport protein V_ATPase_I PF01496.19 KIY43279.1 - 0.58 8.0 19.5 0.93 7.3 19.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SART-1 PF03343.13 KIY43279.1 - 0.64 8.5 30.4 2.9 6.3 0.1 2.1 2 0 0 2 2 2 0 SART-1 family TFB6 PF17110.5 KIY43279.1 - 0.69 9.6 7.8 1.3 8.7 7.8 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH OATP PF03137.20 KIY43279.1 - 0.76 8.0 4.4 1.2 7.4 4.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DDHD PF02862.17 KIY43279.1 - 1.3 9.2 22.2 0.18 12.0 17.6 1.9 2 0 0 2 2 2 0 DDHD domain Cellulose_synt PF03552.14 KIY43279.1 - 1.4 7.3 6.6 2.2 6.6 6.6 1.2 1 0 0 1 1 1 0 Cellulose synthase Connexin PF00029.19 KIY43279.1 - 1.6 8.5 9.6 2.8 7.7 9.6 1.4 1 0 0 1 1 1 0 Connexin Renin_r PF07850.14 KIY43279.1 - 1.6 9.4 7.8 6.1 7.5 7.8 2.0 1 0 0 1 1 1 0 Renin receptor-like protein MAP2_projctn PF08377.10 KIY43279.1 - 3.1 5.7 8.9 4.8 5.1 8.9 1.2 1 0 0 1 1 1 0 MAP2/Tau projection domain Rxt3 PF08642.10 KIY43279.1 - 3.9 8.2 7.9 11 6.8 7.9 1.8 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 HA2 PF04408.23 KIY43279.1 - 5.5 7.3 11.3 24 5.3 11.3 2.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) FAM176 PF14851.6 KIY43279.1 - 6.2 6.5 9.2 13 5.5 9.2 1.5 1 0 0 1 1 1 0 FAM176 family CLN3 PF02487.17 KIY43279.1 - 6.9 5.6 12.3 13 4.7 12.3 1.5 1 0 0 1 1 1 0 CLN3 protein Iwr1 PF08574.10 KIY43280.1 - 7.2e-13 49.4 7.7 7.2e-13 49.4 7.7 2.7 3 0 0 3 3 3 1 Transcription factor Iwr1 Herpes_UL49_2 PF04823.12 KIY43280.1 - 0.14 12.3 0.3 0.74 10.0 0.0 2.4 3 0 0 3 3 3 0 Herpesvirus UL49 tegument protein PH_10 PF15411.6 KIY43281.1 - 2e-36 125.0 0.0 4.4e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KIY43281.1 - 4.8e-33 114.9 3.7 8.2e-33 114.2 3.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KIY43281.1 - 1.2e-17 63.5 0.0 2.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 KIY43281.1 - 3.1e-09 37.0 0.2 5.7e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 CDC24 Calponin SMC_N PF02463.19 KIY43282.1 - 3.1e-72 242.6 12.4 1.1e-71 240.8 12.4 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIY43282.1 - 2.4e-21 76.2 0.1 1.1e-20 74.1 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KIY43282.1 - 2.5e-16 60.8 0.6 2.5e-16 60.8 0.6 7.3 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 KIY43282.1 - 4.6e-15 56.2 9.8 4.8e-08 33.2 0.2 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIY43282.1 - 1.4e-12 48.1 15.8 1.4e-12 48.1 15.8 4.0 3 1 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 KIY43282.1 - 3.5e-05 23.5 0.0 6.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HrpB7 PF09486.10 KIY43282.1 - 0.0012 19.3 1.2 0.0012 19.3 1.2 8.1 4 2 4 8 8 8 3 Bacterial type III secretion protein (HrpB7) DUF4200 PF13863.6 KIY43282.1 - 0.0067 16.8 11.0 0.0067 16.8 11.0 8.7 4 2 2 6 6 6 1 Domain of unknown function (DUF4200) ABC_tran PF00005.27 KIY43282.1 - 0.38 11.3 0.0 0.38 11.3 0.0 6.3 4 3 0 4 4 4 0 ABC transporter Spidroin_N PF16763.5 KIY43282.1 - 2.1 8.4 7.3 16 5.5 1.2 2.8 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term Pkinase PF00069.25 KIY43283.1 - 5.9e-32 111.1 0.0 2.7e-31 108.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43283.1 - 4.5e-09 36.0 0.0 1.2e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY43283.1 - 0.00012 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY43283.1 - 0.00025 20.5 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY43283.1 - 0.012 15.0 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY43283.1 - 0.04 12.7 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PAC4 PF16093.5 KIY43284.1 - 5.1e-15 55.4 0.0 8.9e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 YrvL PF14184.6 KIY43286.1 - 0.075 13.1 2.6 0.13 12.4 2.6 1.4 1 0 0 1 1 1 0 Regulatory protein YrvL NiFe_hyd_3_EhaA PF17367.2 KIY43286.1 - 0.23 11.6 6.8 4.2 7.6 1.1 2.2 1 1 1 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A YesK PF14150.6 KIY43286.1 - 0.74 10.1 4.5 1.6 9.0 4.4 1.7 1 1 0 1 1 1 0 YesK-like protein Adaptin_N PF01602.20 KIY43288.1 - 0.00073 18.2 0.6 0.26 9.8 0.0 2.4 2 1 0 2 2 2 2 Adaptin N terminal region DUF3361 PF11841.8 KIY43288.1 - 0.088 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Ribonuclease_P PF00825.18 KIY43288.1 - 0.14 12.2 0.3 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease P RabGAP-TBC PF00566.18 KIY43289.1 - 2.5e-40 138.4 0.1 3.4e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Fungal_trans PF04082.18 KIY43290.1 - 1.3e-17 63.8 0.4 2.2e-17 63.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY43290.1 - 9.6e-07 28.8 12.1 9.6e-07 28.8 12.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KIY43290.1 - 1.8e-06 28.1 1.1 1.8e-06 28.1 1.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIY43290.1 - 2.1e-06 27.8 16.5 0.0024 18.2 5.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY43290.1 - 0.0019 18.9 19.8 0.0044 17.7 3.4 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIY43290.1 - 0.0022 17.7 3.2 0.29 10.9 0.8 2.9 2 0 0 2 2 2 2 zinc-finger C2H2-type DZR PF12773.7 KIY43290.1 - 7.1 6.7 18.6 0.27 11.3 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_6 PF13912.6 KIY43290.1 - 9.9 6.3 12.0 1.2 9.2 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2370 PF10176.9 KIY43291.1 - 1.1e-64 218.2 0.0 1.6e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF218 PF02698.17 KIY43292.1 - 0.00035 20.6 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Git3 PF11710.8 KIY43293.1 - 1.7e-06 28.0 11.1 3.7e-06 26.9 11.1 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 KIY43293.1 - 0.00022 20.5 11.6 0.00029 20.1 11.6 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Peptidase_M19 PF01244.21 KIY43294.1 - 5.1e-99 331.4 0.0 4.4e-98 328.4 0.0 1.9 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) PM0188 PF11477.8 KIY43294.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Sialyltransferase PMO188 IBR PF01485.21 KIY43295.1 - 2e-19 69.6 31.8 7.5e-11 42.1 5.2 3.9 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KIY43295.1 - 0.01 15.7 0.3 0.01 15.7 0.3 4.7 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 KIY43295.1 - 0.13 12.7 0.0 0.13 12.7 0.0 2.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain US30 PF17624.2 KIY43295.1 - 0.36 9.8 2.4 0.61 9.1 2.4 1.3 1 0 0 1 1 1 0 Family of unknown function Fungal_trans PF04082.18 KIY43296.1 - 1.4e-06 27.5 0.3 4.3e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY43296.1 - 0.00011 22.2 9.1 0.00019 21.5 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.24 KIY43297.1 - 1.4e-88 297.8 0.2 1.8e-88 297.5 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KIY43297.1 - 7.9e-23 80.4 0.0 2.4e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KIY43297.1 - 8.4e-14 51.9 0.5 2.3e-13 50.5 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY43297.1 - 6.8e-12 45.2 0.3 3.5e-10 39.6 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY43297.1 - 3.8e-10 39.8 0.3 3.8e-09 36.6 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIY43297.1 - 2.4e-08 33.8 3.3 4.5e-08 32.9 3.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KIY43297.1 - 3.2e-06 26.5 5.2 0.0001 21.5 1.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIY43297.1 - 8.9e-06 25.2 0.9 1.5e-05 24.4 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIY43297.1 - 2.9e-05 23.0 6.0 0.00015 20.6 0.7 2.9 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 KIY43297.1 - 6.9e-05 22.3 1.8 0.0046 16.3 0.3 3.0 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KIY43297.1 - 0.0002 20.7 2.8 0.02 14.1 0.6 3.0 2 1 1 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.6 KIY43297.1 - 0.00022 20.6 0.1 0.14 11.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIY43297.1 - 0.00028 20.3 0.7 0.00061 19.1 0.7 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KIY43297.1 - 0.016 15.2 0.3 0.089 12.8 0.3 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIY43297.1 - 0.016 14.3 0.2 0.039 13.0 0.3 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KIY43297.1 - 0.029 14.9 0.9 0.069 13.7 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY43297.1 - 0.042 14.3 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AAA_18 PF13238.6 KIY43298.1 - 2e-06 28.4 0.2 1.4e-05 25.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KIY43298.1 - 0.00079 19.2 1.1 0.033 13.9 1.1 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family T2SSE PF00437.20 KIY43298.1 - 0.0064 15.6 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 KIY43298.1 - 0.063 13.5 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIY43298.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KIY43298.1 - 0.71 10.0 2.7 1.3 9.2 0.2 2.5 3 1 0 3 3 3 0 AAA domain DNA_primase_S PF01896.19 KIY43299.1 - 4e-55 186.6 0.1 5.5e-55 186.1 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit Tox-HDC PF15656.6 KIY43299.1 - 0.00036 20.7 0.0 0.0006 20.0 0.0 1.3 1 0 0 1 1 1 1 Toxin with a H, D/N and C signature Rax2 PF12768.7 KIY43300.1 - 0.0012 18.3 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Podoplanin PF05808.11 KIY43300.1 - 0.05 13.7 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Podoplanin G-alpha PF00503.20 KIY43301.1 - 3.1e-90 302.9 0.0 3.7e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY43301.1 - 7.1e-10 38.6 0.2 0.00028 20.4 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 KIY43301.1 - 0.0003 21.0 0.0 0.99 9.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIY43301.1 - 0.00093 18.8 0.2 0.061 12.9 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KIY43301.1 - 0.0015 18.0 0.4 0.0032 16.9 0.2 1.6 2 0 0 2 2 2 1 Bacterial TniB protein Gtr1_RagA PF04670.12 KIY43301.1 - 0.0026 17.2 0.1 0.4 10.0 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KIY43301.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KIY43301.1 - 0.012 15.0 0.0 0.054 12.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KIY43301.1 - 0.028 14.0 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KIY43301.1 - 0.04 13.1 0.1 0.073 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KIY43301.1 - 0.043 14.3 0.0 0.13 12.8 0.0 2.0 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 KIY43301.1 - 0.067 13.0 0.0 0.8 9.5 0.0 2.4 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 KIY43301.1 - 0.07 13.5 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIY43301.1 - 0.077 12.9 0.0 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_2 PF07724.14 KIY43301.1 - 0.098 12.8 0.1 1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KIY43301.1 - 0.11 13.1 0.0 0.94 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIY43301.1 - 0.12 12.7 0.1 0.65 10.3 0.0 2.5 3 1 0 3 3 1 0 AAA domain GTP_cyclohydroI PF01227.22 KIY43301.1 - 0.15 11.4 0.7 0.35 10.3 0.7 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase I Med31 PF05669.12 KIY43302.1 - 1.6e-35 121.0 7.7 1.9e-35 120.7 7.7 1.0 1 0 0 1 1 1 1 SOH1 Peptidase_C12 PF01088.21 KIY43303.1 - 1.7e-53 181.5 0.0 2.8e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KIY43303.1 - 9e-14 51.1 0.0 1.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Zn_clus PF00172.18 KIY43304.1 - 9e-06 25.7 11.2 1.4e-05 25.1 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY43304.1 - 3.3e-05 23.1 0.1 4.7e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPT PF03151.16 KIY43305.1 - 3.3e-25 89.0 15.1 4.1e-25 88.7 15.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIY43305.1 - 2e-08 34.5 30.3 2.2e-05 24.7 11.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KIY43305.1 - 0.00053 19.3 15.0 0.0013 18.1 15.0 1.6 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KIY43305.1 - 0.041 13.1 16.8 0.29 10.3 16.8 2.1 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Methyltransf_2 PF00891.18 KIY43306.1 - 1.4e-18 66.9 0.0 7e-18 64.7 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 KIY43306.1 - 0.0016 18.4 0.0 0.0048 16.8 0.0 1.8 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_12 PF08242.12 KIY43306.1 - 0.016 16.0 0.0 0.032 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIY43306.1 - 0.063 14.0 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MarR_2 PF12802.7 KIY43306.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 KIY43306.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Methyltransf_31 PF13847.6 KIY43306.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ParA PF10609.9 KIY43306.1 - 0.19 11.2 0.0 0.65 9.4 0.0 1.7 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase KH_8 PF17903.1 KIY43307.1 - 6.9e-32 109.4 2.1 4e-31 106.9 0.0 2.6 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 KIY43307.1 - 0.0017 18.1 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KIY43307.1 - 0.027 14.3 0.1 0.095 12.6 0.0 2.0 2 0 0 2 2 2 0 KH domain DUF966 PF06136.13 KIY43307.1 - 4.8 6.8 15.9 6.4 6.4 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) eIF3g PF12353.8 KIY43308.1 - 1.1e-41 142.2 2.3 1.1e-41 142.2 2.3 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KIY43308.1 - 2.1e-17 62.7 0.1 4e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Neuregulin PF02158.15 KIY43308.1 - 0.0025 17.3 1.6 0.0031 16.9 1.6 1.2 1 0 0 1 1 1 1 Neuregulin intracellular region DNA_methylase PF00145.17 KIY43308.1 - 0.14 11.4 2.3 0.18 11.1 2.3 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase RRM_5 PF13893.6 KIY43308.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HpcH_HpaI PF03328.14 KIY43309.1 - 2.3e-31 108.6 0.3 2.9e-31 108.3 0.3 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family AA_permease PF00324.21 KIY43310.1 - 8.6e-102 341.2 31.4 5.1e-101 338.6 31.4 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY43310.1 - 4.1e-32 111.5 31.4 8.9e-31 107.1 31.4 2.0 1 1 0 1 1 1 1 Amino acid permease MBOAT PF03062.19 KIY43311.1 - 0.074 12.4 0.2 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family NTP_transferase PF00483.23 KIY43312.1 - 4.5e-39 134.5 0.0 1.7e-38 132.6 0.0 1.9 3 0 0 3 3 3 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIY43312.1 - 2.1e-06 28.2 0.1 5e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 KIY43312.1 - 0.00043 20.2 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase DivIC PF04977.15 KIY43312.1 - 0.31 10.8 2.7 0.18 11.6 0.5 1.7 2 0 0 2 2 2 0 Septum formation initiator EVC2_like PF12297.8 KIY43313.1 - 0.26 9.9 1.5 0.27 9.9 1.5 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Ish1 PF10281.9 KIY43315.1 - 5e-58 193.1 28.6 2e-11 44.0 2.6 7.9 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KIY43315.1 - 5.3e-05 22.9 0.0 5.3 6.9 0.0 4.9 5 0 0 5 5 5 1 SAP domain HeH PF12949.7 KIY43315.1 - 0.00013 21.6 0.0 0.35 10.6 0.0 4.1 4 1 0 4 4 4 1 HeH/LEM domain ANT PF03374.14 KIY43315.1 - 0.0053 17.0 2.9 2.3 8.6 0.0 4.9 1 1 5 7 7 7 1 Phage antirepressor protein KilAC domain EutB PF06751.11 KIY43315.1 - 0.054 12.3 0.1 0.094 11.5 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) LEM PF03020.15 KIY43315.1 - 0.077 12.6 0.0 30 4.3 0.0 3.3 3 0 0 3 3 3 0 LEM domain DnaGprimase_HBD PF16730.5 KIY43315.1 - 0.085 12.9 0.0 0.98 9.5 0.0 2.7 4 0 0 4 4 4 0 DnaG-primase C-terminal, helicase-binding domain TryThrA_C PF12319.8 KIY43315.1 - 0.12 11.8 21.6 0.11 12.0 5.8 3.5 3 1 0 3 3 3 0 Tryptophan-Threonine-rich plasmodium antigen C terminal YtxH PF12732.7 KIY43315.1 - 0.18 12.3 3.8 46 4.6 0.0 4.6 4 3 0 4 4 4 0 YtxH-like protein LRR_8 PF13855.6 KIY43318.1 - 0.052 13.3 0.2 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Leucine rich repeat HAD_2 PF13419.6 KIY43320.1 - 0.00068 19.8 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY43320.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 HAD-hyrolase-like Pkinase PF00069.25 KIY43321.1 - 3.8e-52 177.3 0.0 6.8e-52 176.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43321.1 - 7e-23 81.2 0.0 1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIY43321.1 - 0.0012 18.5 0.2 0.003 17.2 0.1 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KIY43321.1 - 0.002 18.1 0.1 0.002 18.1 0.1 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY43321.1 - 0.043 13.4 0.4 0.1 12.2 0.4 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase TFIIA PF03153.13 KIY43321.1 - 4.6 7.1 22.9 6.6 6.6 22.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3512 PF12024.8 KIY43323.1 - 0.0051 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) GHMP_kinases_N PF00288.26 KIY43324.1 - 5.6e-09 36.1 0.1 1.1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIY43324.1 - 0.0029 17.9 0.0 0.0085 16.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Cyclin_N PF00134.23 KIY43325.1 - 2.8e-11 43.3 0.3 1.1e-09 38.1 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Retrotran_gag_2 PF14223.6 KIY43329.1 - 0.0016 18.1 0.2 0.0019 17.9 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type GYF PF02213.16 KIY43330.1 - 2.5e-06 27.0 0.8 7e-06 25.6 0.8 1.8 1 0 0 1 1 1 1 GYF domain DUF5546 PF17700.1 KIY43330.1 - 0.22 11.9 0.0 0.37 11.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5546) SNF2_N PF00176.23 KIY43331.1 - 8.2e-56 189.2 0.0 1.3e-55 188.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KIY43331.1 - 1.5e-45 155.6 7.9 3.2e-45 154.5 7.9 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KIY43331.1 - 1.2e-16 61.0 0.0 3.5e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY43331.1 - 4.8e-06 26.7 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIY43331.1 - 1.4e-05 24.5 0.0 2.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KIY43331.1 - 3.1e-05 23.3 0.4 0.00019 20.7 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 U1snRNP70_N PF12220.8 KIY43331.1 - 0.35 11.6 3.3 0.21 12.3 0.3 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PRP4 PF08799.11 KIY43331.1 - 0.58 9.8 2.4 1.8 8.2 2.4 1.9 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Epimerase PF01370.21 KIY43332.1 - 6.9e-15 55.2 0.1 7.9e-15 55.0 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY43332.1 - 6.1e-13 49.1 1.0 7.1e-13 48.8 1.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY43332.1 - 4.4e-10 39.0 0.0 5.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY43332.1 - 3.9e-07 29.5 0.8 6.5e-05 22.2 0.8 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIY43332.1 - 1.8e-06 27.6 0.1 2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIY43332.1 - 0.00011 21.8 0.2 0.00014 21.5 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KIY43332.1 - 0.00035 19.8 0.1 0.00057 19.1 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIY43332.1 - 0.023 14.2 0.7 0.071 12.6 0.7 2.1 1 1 0 1 1 1 0 short chain dehydrogenase DUF3535 PF12054.8 KIY43333.1 - 7e-93 312.2 2.5 4.7e-92 309.5 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KIY43333.1 - 1e-63 215.2 0.0 2.3e-63 214.0 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY43333.1 - 9.4e-17 61.4 0.0 2.2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KIY43333.1 - 5.4e-11 41.8 17.7 0.18 12.2 0.0 10.3 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 KIY43333.1 - 0.0017 18.8 19.1 3.6 8.2 0.0 7.9 9 0 0 9 9 9 2 HEAT-like repeat DUF3385 PF11865.8 KIY43333.1 - 0.0049 16.8 1.3 0.026 14.4 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Dopey_N PF04118.14 KIY43333.1 - 0.0054 15.9 0.1 0.016 14.3 0.1 1.8 1 0 0 1 1 1 1 Dopey, N-terminal HEAT_2 PF13646.6 KIY43333.1 - 0.011 16.2 11.3 17 5.9 0.0 7.1 8 0 0 8 8 7 0 HEAT repeats Vac14_Fab1_bd PF12755.7 KIY43333.1 - 0.014 15.9 0.0 1.1 9.9 0.0 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KIY43333.1 - 0.022 14.3 0.2 0.23 11.0 0.0 2.8 3 1 0 3 3 3 0 CLASP N terminal BLM10_mid PF16507.5 KIY43333.1 - 0.087 11.5 0.8 0.88 8.1 0.0 2.4 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, mid region SOG2 PF10428.9 KIY43334.1 - 2.5e-74 251.3 7.0 2.5e-74 251.3 7.0 3.1 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.6 KIY43334.1 - 1.5e-14 53.5 0.3 3.7e-09 36.2 0.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIY43334.1 - 2.2e-12 47.0 0.2 6.6e-05 23.2 0.1 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KIY43334.1 - 0.00018 21.1 0.8 0.00076 19.0 0.6 1.9 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KIY43334.1 - 0.036 14.6 0.0 3.6e+02 2.4 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KIY43334.1 - 0.12 12.5 2.1 21 5.5 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat Cupin_8 PF13621.6 KIY43335.1 - 1.3e-29 103.7 0.0 1.7e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KIY43335.1 - 6.8e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KIY43335.1 - 0.0011 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 KIY43335.1 - 0.013 15.9 0.1 0.042 14.3 0.0 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_3 PF05899.12 KIY43335.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) FAD-oxidase_C PF02913.19 KIY43337.1 - 1.1e-58 198.9 0.2 1.5e-58 198.4 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIY43337.1 - 3.7e-33 114.2 0.0 6.3e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Cullin_binding PF03556.15 KIY43338.1 - 2.9e-24 85.8 1.4 2.9e-24 85.8 1.4 1.4 2 0 0 2 2 2 1 Cullin binding Aldo_ket_red PF00248.21 KIY43339.1 - 4.9e-74 249.2 0.0 5.5e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PTCB-BRCT PF12738.7 KIY43340.1 - 6.8e-20 70.8 3.1 1.8e-12 47.0 0.3 4.5 4 0 0 4 4 4 2 twin BRCT domain RTT107_BRCT_5 PF16770.5 KIY43340.1 - 2e-17 62.9 0.0 6.7e-16 58.0 0.0 2.9 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KIY43340.1 - 3.9e-12 46.4 0.0 0.1 13.0 0.0 6.0 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY43340.1 - 1.8e-11 44.3 0.0 4.3e-07 30.2 0.0 4.7 5 0 0 5 5 5 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIY43340.1 - 1.2e-06 28.7 4.7 1.3 9.4 0.9 5.7 6 0 0 6 6 6 2 DNA ligase 3 BRCT domain Biotin_lipoyl_2 PF13533.6 KIY43340.1 - 0.18 11.6 0.2 0.53 10.1 0.2 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like CLTH PF10607.9 KIY43341.1 - 1.4e-31 109.4 0.0 1.8e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIY43341.1 - 1e-10 41.2 0.1 1.8e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 LisH CSTF1_dimer PF16699.5 KIY43341.1 - 0.021 14.6 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Cleavage stimulation factor subunit 1, dimerisation domain COesterase PF00135.28 KIY43343.1 - 2.4e-93 313.7 0.0 3.1e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY43343.1 - 1.5e-06 28.2 0.0 7e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY43343.1 - 0.069 12.6 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_M24 PF00557.24 KIY43344.1 - 2e-47 161.6 0.0 2.5e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KIY43344.1 - 7e-12 45.5 10.5 1.3e-11 44.6 10.5 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Cpn10 PF00166.21 KIY43346.1 - 1.1e-26 92.7 0.0 1.2e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit TruB_N PF01509.18 KIY43347.1 - 9.2e-44 149.4 0.0 3.6e-43 147.5 0.0 1.8 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KIY43347.1 - 0.00044 20.4 0.0 0.002 18.2 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain PNTB PF02233.16 KIY43348.1 - 3.3e-174 580.1 21.2 3.3e-174 580.1 21.2 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KIY43348.1 - 4.5e-73 245.1 0.9 1.3e-72 243.6 0.9 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KIY43348.1 - 4.7e-42 143.5 0.0 1.4e-41 142.0 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KIY43348.1 - 8.6e-32 109.5 4.3 8.6e-32 109.5 4.3 4.7 2 1 3 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Pyr_redox_2 PF07992.14 KIY43348.1 - 0.042 13.1 0.4 0.099 11.9 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIY43348.1 - 0.086 12.2 0.5 5 6.5 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Citrate_bind PF16114.5 KIY43348.1 - 0.087 12.3 0.4 0.47 9.9 0.0 2.3 3 0 0 3 3 3 0 ATP citrate lyase citrate-binding TPP_enzyme_M PF00205.22 KIY43348.1 - 0.11 12.2 0.6 1.1 8.9 0.3 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DHDPS PF00701.22 KIY43349.1 - 5.2e-28 97.6 0.0 2.9e-25 88.6 0.0 2.0 1 1 0 2 2 2 2 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 KIY43350.1 - 7.3e-34 117.2 31.7 7.3e-34 117.2 31.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY43350.1 - 4.3e-07 29.2 10.6 4.3e-07 29.2 10.6 3.2 2 2 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KIY43350.1 - 3.2e-05 22.5 2.8 3.2e-05 22.5 2.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Neur_chan_memb PF02932.16 KIY43350.1 - 0.094 12.8 1.4 0.17 11.9 1.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1523 PF07509.11 KIY43350.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) ANAPC4_WD40 PF12894.7 KIY43351.1 - 1.8e-08 34.5 0.5 6.1 7.2 0.0 5.5 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY43351.1 - 4.8e-05 24.0 5.2 1.9 9.5 0.0 6.5 7 0 0 7 7 7 1 WD domain, G-beta repeat eIF2A PF08662.11 KIY43351.1 - 0.017 15.0 0.1 24 4.7 0.0 3.8 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.9 KIY43351.1 - 0.2 10.8 0.0 24 4.0 0.0 2.6 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller IKI3 PF04762.12 KIY43351.1 - 0.49 8.3 1.0 9.8 4.0 0.0 2.8 3 0 0 3 3 3 0 IKI3 family Nuc_sug_transp PF04142.15 KIY43352.1 - 2.5e-100 335.7 14.9 3.1e-100 335.4 14.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KIY43352.1 - 0.00017 20.9 12.1 0.00029 20.1 12.1 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIY43352.1 - 0.00033 20.8 0.9 0.00033 20.8 0.9 2.9 3 0 0 3 3 3 2 EamA-like transporter family Glycos_transf_3 PF00591.21 KIY43354.1 - 2.6e-71 240.2 0.0 3.7e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KIY43354.1 - 3.3e-09 36.4 0.0 5.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain PQ-loop PF04193.14 KIY43355.1 - 3.5e-37 126.0 7.5 3e-18 65.4 0.9 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KIY43355.1 - 0.0088 16.1 0.6 0.025 14.6 0.6 1.7 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange BRCT_2 PF16589.5 KIY43356.1 - 0.00011 22.6 0.1 0.037 14.4 0.0 2.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY43356.1 - 0.0026 18.1 0.1 0.095 13.1 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KIY43356.1 - 0.005 16.7 0.0 0.054 13.4 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KIY43356.1 - 0.24 11.5 1.7 6.2 6.9 0.3 2.5 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Chromo PF00385.24 KIY43357.1 - 4.9e-07 29.5 2.4 8.9e-07 28.7 2.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2367 PF10164.9 KIY43358.1 - 2.2e-10 41.0 4.0 2.5e-10 40.8 4.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) ATP1G1_PLM_MAT8 PF02038.16 KIY43358.1 - 0.34 10.4 4.3 0.5 9.8 4.3 1.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family SH2_2 PF14633.6 KIY43359.1 - 8.7e-76 254.1 0.2 8.7e-76 254.1 0.2 2.3 2 0 0 2 2 1 1 SH2 domain HHH_7 PF14635.6 KIY43359.1 - 3.3e-28 98.1 0.0 8.8e-28 96.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KIY43359.1 - 2.1e-26 92.5 0.0 5.3e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KIY43359.1 - 2.3e-22 79.6 0.0 5.9e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KIY43359.1 - 4.3e-21 75.3 25.4 4.3e-21 75.3 25.4 5.1 4 2 0 4 4 2 1 Acidic N-terminal SPT6 SH2 PF00017.24 KIY43359.1 - 9e-07 28.9 0.0 2.1e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 SH2 domain HHH_9 PF17674.1 KIY43359.1 - 3e-06 28.1 0.5 1.4e-05 25.9 0.5 2.3 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 KIY43359.1 - 4.2e-05 23.8 0.2 0.00011 22.5 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 KIY43359.1 - 0.054 13.8 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif CT_C_D PF02682.16 KIY43359.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D DUF2288 PF10052.9 KIY43359.1 - 0.13 12.3 1.3 0.35 11.0 0.1 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2288) RRM_1 PF00076.22 KIY43360.1 - 1.3e-81 268.4 4.7 7.8e-21 73.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KIY43360.1 - 1.2e-25 89.4 0.8 4.8e-25 87.5 0.6 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 KIY43360.1 - 4e-05 23.6 0.6 7 6.9 0.0 4.7 4 1 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KIY43360.1 - 7.5e-05 22.6 1.2 1.8 8.6 0.1 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIY43360.1 - 0.00094 19.2 8.5 0.35 10.9 3.3 3.8 4 0 0 4 4 4 1 RNA binding motif YflT PF11181.8 KIY43360.1 - 0.0017 18.8 4.7 0.038 14.5 0.7 3.0 3 0 0 3 3 3 1 Heat induced stress protein YflT OB_RNB PF08206.11 KIY43360.1 - 0.0048 16.6 0.8 11 5.8 0.1 3.4 3 0 0 3 3 3 2 Ribonuclease B OB domain Limkain-b1 PF11608.8 KIY43360.1 - 0.026 14.6 0.7 2.7 8.1 0.1 3.4 3 0 0 3 3 3 0 Limkain b1 DUF4407 PF14362.6 KIY43360.1 - 0.045 13.1 3.0 0.064 12.6 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nefa_Nip30_N PF10187.9 KIY43360.1 - 0.54 10.6 6.5 0.42 11.0 0.5 2.6 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 adh_short_C2 PF13561.6 KIY43361.1 - 5.2e-48 163.6 2.2 6.1e-48 163.4 2.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY43361.1 - 1.3e-46 158.5 0.5 1.7e-46 158.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY43361.1 - 0.00097 19.1 0.4 0.0018 18.2 0.4 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIY43361.1 - 0.024 14.5 0.5 0.34 10.8 0.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KIY43361.1 - 0.049 13.1 0.3 1 8.8 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KIY43361.1 - 0.056 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UDPGT PF00201.18 KIY43362.1 - 1.2e-14 54.1 0.0 2.9e-14 52.7 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase SPX PF03105.19 KIY43363.1 - 1.3 8.8 3.5 2 8.3 3.5 1.2 1 0 0 1 1 1 0 SPX domain RPA_C PF08784.11 KIY43364.1 - 4.6e-10 40.1 1.0 4.6e-10 40.1 1.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KIY43364.1 - 6.5e-06 26.0 0.3 1.1e-05 25.3 0.3 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KIY43364.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 STN PF07660.14 KIY43364.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain NatB_MDM20 PF09797.9 KIY43365.1 - 8e-71 239.0 3.3 8e-71 239.0 3.3 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KIY43365.1 - 2.8e-05 24.5 1.9 0.52 10.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY43365.1 - 5.1e-05 23.8 2.4 1 10.4 0.1 6.1 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIY43365.1 - 0.0041 16.4 1.0 0.0041 16.4 1.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 KIY43365.1 - 0.1 13.0 7.3 0.099 13.1 0.5 3.6 3 1 0 3 3 3 0 Bacterial transcriptional activator domain K_oxygenase PF13434.6 KIY43366.1 - 1.3e-95 320.5 0.0 1.6e-95 320.2 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIY43366.1 - 2.7e-05 24.2 0.0 0.00042 20.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIY43366.1 - 0.0025 17.1 0.0 0.029 13.6 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY43366.1 - 0.047 14.2 0.1 5.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 KIY43367.1 - 6.4e-12 45.6 0.0 9e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY43367.1 - 4.3e-10 40.2 0.0 7.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY43367.1 - 9.9e-10 38.9 0.0 2.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY43367.1 - 3e-06 27.1 0.0 0.007 16.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KIY43367.1 - 1.5e-05 25.7 0.0 4.9e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY43367.1 - 0.00069 19.0 0.0 0.003 16.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KIY43367.1 - 0.00071 19.1 0.0 0.011 15.2 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 KIY43367.1 - 0.0026 16.4 0.0 0.015 13.9 0.0 1.8 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 KIY43367.1 - 0.014 14.7 0.0 0.11 11.8 0.0 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KIY43367.1 - 0.056 12.7 0.1 0.26 10.6 0.1 2.2 1 1 1 2 2 2 0 O-methyltransferase domain MTS PF05175.14 KIY43367.1 - 0.11 12.0 0.0 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Ribosomal_S10 PF00338.22 KIY43368.1 - 4.8e-28 97.3 0.5 5.8e-28 97.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L24e PF01246.20 KIY43369.1 - 3.5e-32 110.4 5.7 8e-32 109.3 5.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 KIY43369.1 - 0.0073 16.2 3.6 0.013 15.4 3.6 1.4 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif zf-FLZ PF04570.14 KIY43369.1 - 0.18 11.3 1.6 0.45 10.0 1.6 1.6 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2849 PF11011.8 KIY43369.1 - 0.21 12.3 1.5 0.25 12.1 0.5 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2849) ATG_C PF09333.11 KIY43370.1 - 4e-35 120.0 0.0 1.4e-34 118.3 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 KIY43370.1 - 2.4e-13 50.1 0.0 6.6e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 KIY43370.1 - 2e-12 47.2 0.0 6.2e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KIY43370.1 - 0.00031 20.6 0.0 0.00069 19.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal zf-H2C2_2 PF13465.6 KIY43371.1 - 3.1e-07 30.5 38.6 0.0077 16.6 2.7 5.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY43371.1 - 0.0007 20.2 37.3 0.4 11.6 2.0 6.1 5 1 1 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY43371.1 - 0.0022 18.3 39.7 0.037 14.5 2.2 6.0 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KIY43371.1 - 0.0058 17.3 10.6 0.12 13.1 0.2 4.2 1 1 2 4 4 4 1 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KIY43371.1 - 0.017 14.8 0.1 0.017 14.8 0.1 4.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KIY43371.1 - 0.19 11.8 0.3 0.19 11.8 0.3 5.0 6 0 0 6 6 6 0 C2H2-type zinc finger Toxin_8 PF07365.12 KIY43371.1 - 5.4 7.3 9.8 1.2 9.4 0.3 3.2 3 0 0 3 3 3 0 Alpha conotoxin precursor polyprenyl_synt PF00348.17 KIY43372.1 - 1e-63 214.8 0.0 1.2e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SRP54 PF00448.22 KIY43373.1 - 1.9e-72 243.1 2.0 3.4e-72 242.2 2.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KIY43373.1 - 3.5e-30 104.6 0.8 3.5e-30 104.6 0.8 4.1 4 0 0 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KIY43373.1 - 7.6e-19 67.7 4.6 1.9e-18 66.5 4.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KIY43373.1 - 8.1e-06 25.5 0.3 2e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KIY43373.1 - 0.00099 19.3 0.1 0.002 18.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIY43373.1 - 0.0044 17.4 0.2 0.0044 17.4 0.2 2.5 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KIY43373.1 - 0.007 16.1 0.7 0.069 12.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KIY43373.1 - 0.0073 16.4 0.0 0.02 14.9 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KIY43373.1 - 0.019 14.3 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 KIY43373.1 - 0.057 12.4 6.0 0.014 14.4 1.0 2.5 2 2 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 KIY43373.1 - 0.063 13.1 0.1 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KIY43373.1 - 0.088 12.2 1.0 13 5.2 0.1 2.7 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIY43373.1 - 0.14 12.2 0.2 0.6 10.2 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase HTH_ParB PF17762.1 KIY43373.1 - 0.18 11.6 1.7 5.6 6.8 0.1 2.6 2 0 0 2 2 2 0 HTH domain found in ParB protein Inv-AAD PF18785.1 KIY43375.1 - 1.8e-26 92.5 0.1 4.9e-26 91.1 0.1 1.6 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KIY43375.1 - 4.8e-12 45.7 0.3 7.4e-11 41.8 0.3 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KIY43375.1 - 0.0061 16.5 0.0 0.059 13.3 0.0 2.0 1 1 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.6 KIY43375.1 - 0.053 13.3 0.0 3.4 7.4 0.1 2.3 2 0 0 2 2 2 0 MafB19-like deaminase PRCC PF10253.9 KIY43376.1 - 1.1e-30 108.1 4.4 1.1e-30 108.1 4.4 3.3 2 2 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting TSNAXIP1_N PF15739.5 KIY43376.1 - 0.0059 17.0 1.9 0.011 16.1 0.3 1.9 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus WD40 PF00400.32 KIY43377.1 - 3.5e-14 53.0 14.5 0.014 16.3 0.3 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY43377.1 - 0.0015 18.8 0.0 2.2 8.6 0.0 3.8 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY43377.1 - 0.12 11.3 0.0 0.71 8.8 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lipase_GDSL PF00657.22 KIY43378.1 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DLH PF01738.18 KIY43379.1 - 1.8e-13 50.6 0.0 2.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Prenylcys_lyase PF07156.14 KIY43380.1 - 2e-57 195.0 0.1 2.9e-57 194.5 0.1 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KIY43380.1 - 7e-09 35.8 0.0 1.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY43380.1 - 4.4e-08 33.1 0.6 0.0093 15.6 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIY43380.1 - 2.7e-06 27.0 0.1 4.9e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KIY43380.1 - 0.001 19.1 0.0 0.094 12.7 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIY43380.1 - 0.068 12.4 0.0 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY43380.1 - 0.19 10.7 0.2 0.28 10.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Alpha-amylase PF00128.24 KIY43381.1 - 1.1e-22 81.1 0.0 2.2e-18 66.9 0.0 2.7 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KIY43381.1 - 7.8e-14 52.0 0.0 1.6e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KIY43381.1 - 6.8e-07 29.0 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 WD40 PF00400.32 KIY43382.1 - 2.3e-08 34.5 8.5 0.0041 17.9 0.6 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ubiquitin PF00240.23 KIY43383.1 - 3.3e-26 90.8 0.0 3.6e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIY43383.1 - 4.5e-12 45.6 0.1 4.9e-12 45.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIY43383.1 - 4.1e-05 24.0 0.0 0.00015 22.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KIY43383.1 - 5.2e-05 23.1 0.0 6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Thi4 PF01946.17 KIY43384.1 - 2.9e-103 344.1 0.3 3.6e-103 343.9 0.3 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIY43384.1 - 1.7e-09 37.7 3.5 2.5e-08 33.9 0.8 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIY43384.1 - 3.2e-08 33.0 1.2 3e-07 29.8 1.2 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY43384.1 - 2.7e-07 30.1 0.1 4.2e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY43384.1 - 2.8e-07 30.7 0.1 7.1e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY43384.1 - 2.9e-07 29.9 4.1 3.3e-05 23.1 0.4 2.9 2 1 1 3 3 3 2 FAD binding domain NAD_binding_9 PF13454.6 KIY43384.1 - 7.9e-06 25.9 2.9 8.4e-05 22.6 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KIY43384.1 - 3.2e-05 23.5 0.7 3.2e-05 23.5 0.7 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY43384.1 - 0.00016 20.6 0.2 0.00023 20.0 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GMC_oxred_N PF00732.19 KIY43384.1 - 0.003 17.0 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.22 KIY43384.1 - 0.018 14.2 0.2 0.054 12.6 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 KIY43384.1 - 0.028 13.7 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KIY43384.1 - 0.029 13.6 0.1 0.056 12.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY43384.1 - 0.049 14.2 0.1 0.17 12.5 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY43384.1 - 0.11 11.4 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase ERCC4 PF02732.15 KIY43385.1 - 0.00073 19.8 0.3 0.0026 18.0 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain Med3 PF11593.8 KIY43385.1 - 2 7.5 10.3 3.6 6.7 10.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Tho2 PF11262.8 KIY43385.1 - 2.3 7.3 7.9 5.1 6.2 7.9 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SAPS PF04499.15 KIY43385.1 - 4.2 6.1 9.1 6.9 5.3 9.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MFS_1 PF07690.16 KIY43386.1 - 3.8e-28 98.4 35.9 4.9e-28 98.1 35.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3458_C PF17432.2 KIY43386.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats Epimerase PF01370.21 KIY43387.1 - 1.5e-09 37.7 0.0 1.8e-05 24.3 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY43387.1 - 0.00042 19.4 0.0 0.67 8.9 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIY43387.1 - 0.0032 16.9 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIY43387.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KIY43387.1 - 0.017 14.6 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KIY43387.1 - 0.025 13.8 0.2 0.052 12.7 0.0 1.9 2 1 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 KIY43387.1 - 0.052 12.7 0.0 0.18 10.8 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain SCAMP PF04144.13 KIY43388.1 - 4.6e-53 180.1 4.3 5.9e-53 179.7 4.3 1.0 1 0 0 1 1 1 1 SCAMP family PyrBI_leader PF08052.11 KIY43388.1 - 0.057 13.4 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 PyrBI operon leader peptide DUF3958 PF13125.6 KIY43388.1 - 0.48 10.7 4.2 12 6.1 1.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) Phage-Gp8 PF09215.10 KIY43389.1 - 0.23 10.5 0.0 0.24 10.4 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 PknH_C PF14032.6 KIY43391.1 - 0.00074 19.4 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 PknH-like extracellular domain DUF3446 PF11928.8 KIY43392.1 - 1.1 9.7 7.3 1.6 9.1 7.3 1.4 1 1 0 1 1 1 0 Early growth response N-terminal domain Pkinase PF00069.25 KIY43393.1 - 6.3e-71 238.8 0.0 7.3e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43393.1 - 2.8e-48 164.5 0.0 3.7e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY43393.1 - 4.2e-06 26.3 0.0 8e-05 22.1 0.0 2.3 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KIY43393.1 - 0.0013 17.6 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF5039 PF16442.5 KIY43393.1 - 0.17 11.4 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) Zn_ribbon_17 PF17120.5 KIY43394.1 - 3.1e-05 23.5 5.7 3.1e-05 23.5 5.7 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KIY43394.1 - 0.0014 19.4 8.0 1.1 10.2 0.3 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-CRD PF17979.1 KIY43394.1 - 0.11 12.6 11.7 0.25 11.4 11.7 1.6 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Translin PF01997.16 KIY43395.1 - 3.9e-55 187.0 0.0 5.5e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Translin family Pro_isomerase PF00160.21 KIY43398.1 - 8e-27 94.4 0.0 8.6e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRM PF02005.16 KIY43399.1 - 1.6e-119 399.4 0.0 2.1e-119 399.0 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KIY43399.1 - 0.0017 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein zinc_ribbon_15 PF17032.5 KIY43399.1 - 0.21 12.3 0.2 0.21 12.3 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon family AA_permease_2 PF13520.6 KIY43400.1 - 1.6e-62 211.8 36.6 2e-62 211.4 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY43400.1 - 4.1e-32 111.4 29.5 5.8e-32 110.9 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease HMA PF00403.26 KIY43401.1 - 1.4e-09 38.3 1.4 2.2e-09 37.6 1.4 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Ribosomal_L44 PF00935.19 KIY43401.1 - 0.11 13.0 0.2 0.11 13.0 0.2 1.5 2 0 0 2 2 2 0 Ribosomal protein L44 Ferric_reduct PF01794.19 KIY43402.1 - 1.3e-17 64.0 14.4 1.3e-17 64.0 14.4 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIY43402.1 - 7e-12 45.7 0.0 4.4e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIY43402.1 - 5e-08 33.0 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Sdh_cyt PF01127.22 KIY43402.1 - 0.014 15.4 4.8 0.014 15.4 4.8 3.1 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit AA_permease PF00324.21 KIY43403.1 - 6.1e-100 335.1 33.5 7.7e-100 334.8 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY43403.1 - 1e-17 64.1 34.2 1.4e-17 63.7 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease Nucleoporin_C PF03177.14 KIY43404.1 - 1.2e-74 252.2 0.0 1.9e-74 251.5 0.0 1.3 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KIY43404.1 - 1.2e-19 70.4 0.0 1.7e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like MaoC_dehydratas PF01575.19 KIY43405.1 - 0.029 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain Ytp1 PF10355.9 KIY43406.1 - 7.3e-60 202.5 18.2 7.3e-60 202.5 18.2 2.9 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KIY43406.1 - 3.1e-29 100.9 0.3 3.1e-29 100.9 0.3 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) zf-BED PF02892.15 KIY43407.1 - 0.14 12.2 0.7 0.31 11.1 0.7 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.6 KIY43407.1 - 0.23 12.4 1.0 0.71 10.9 1.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger C1_1 PF00130.22 KIY43409.1 - 2.9e-05 23.9 5.2 2.9e-05 23.9 5.2 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAPPC9-Trs120 PF08626.11 KIY43410.1 - 4.1e-200 667.1 0.0 4e-199 663.8 0.0 1.9 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Elf1 PF05129.13 KIY43412.1 - 2e-29 101.5 0.7 2.4e-29 101.2 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like PHD_4 PF16866.5 KIY43412.1 - 0.012 15.7 0.4 0.017 15.2 0.4 1.3 1 0 0 1 1 1 0 PHD-finger zf-CHY PF05495.12 KIY43412.1 - 0.037 14.5 1.3 0.05 14.1 1.3 1.2 1 0 0 1 1 1 0 CHY zinc finger Kinesin PF00225.23 KIY43413.1 - 1.4e-106 356.2 0.0 3.5e-106 354.9 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY43413.1 - 2.1e-23 82.9 0.0 1.4e-22 80.2 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 KIY43413.1 - 0.00054 20.4 1.7 0.00054 20.4 1.7 3.6 4 0 0 4 4 4 1 Kinesin-associated microtubule-binding HrpF PF06266.12 KIY43413.1 - 0.37 11.1 2.3 0.53 10.6 0.2 2.5 2 0 0 2 2 2 0 HrpF protein Baculo_PEP_C PF04513.12 KIY43413.1 - 3.1 7.8 11.4 7.2 6.7 0.2 4.2 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps55 PF04133.14 KIY43414.1 - 4.7e-43 145.9 5.1 5.3e-43 145.7 5.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 CbiQ PF02361.16 KIY43414.1 - 0.14 11.7 3.5 0.3 10.7 3.5 1.6 1 1 0 1 1 1 0 Cobalt transport protein RNase_PH PF01138.21 KIY43415.1 - 8e-30 104.0 0.2 1.2e-29 103.5 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIY43415.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Glyco_transf_15 PF01793.16 KIY43416.1 - 2.9e-122 408.0 4.6 3.9e-122 407.6 4.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PI3_PI4_kinase PF00454.27 KIY43419.1 - 7.2e-33 114.4 0.0 1.1e-31 110.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KIY43419.1 - 0.048 13.1 0.1 0.082 12.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ADH_zinc_N PF00107.26 KIY43420.1 - 5.7e-28 97.5 0.7 1.1e-26 93.3 0.7 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY43420.1 - 1.9e-17 64.6 0.0 4e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY43420.1 - 5.8e-12 45.5 0.0 1.8e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KIY43420.1 - 0.00044 20.5 0.0 0.00095 19.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KIY43420.1 - 0.018 14.4 0.7 0.026 13.8 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.6 KIY43420.1 - 0.037 14.0 0.1 0.13 12.3 0.0 2.0 3 0 0 3 3 3 0 SIS domain Mem_trans PF03547.18 KIY43421.1 - 5.4e-32 110.6 9.6 5e-27 94.3 1.6 2.8 2 1 0 2 2 2 2 Membrane transport protein Hydrophobin PF01185.18 KIY43422.1 - 1.5e-18 67.2 8.7 2e-18 66.8 8.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin FHA PF00498.26 KIY43423.1 - 4.2e-16 59.1 0.0 9.2e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIY43423.1 - 0.0017 18.7 0.1 0.0063 16.8 0.0 2.0 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain YabA PF06156.13 KIY43423.1 - 0.026 15.2 1.2 0.085 13.5 1.2 1.8 1 0 0 1 1 1 0 Initiation control protein YabA FlaC_arch PF05377.11 KIY43423.1 - 0.35 11.3 1.7 0.86 10.0 1.7 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KIY43423.1 - 4 7.3 9.3 0.33 10.7 2.9 2.2 2 0 0 2 2 2 0 Septum formation initiator RRM_1 PF00076.22 KIY43425.1 - 8.8e-16 57.5 0.1 3.7e-15 55.5 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY43425.1 - 5.8e-08 32.8 0.0 7.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KIY43425.1 - 0.00085 19.3 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KIY43425.1 - 0.0044 16.9 0.0 0.0074 16.2 0.0 1.3 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Methyltransf_11 PF08241.12 KIY43426.1 - 4.9e-17 62.4 0.0 7.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY43426.1 - 2.6e-13 50.5 0.0 7.8e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY43426.1 - 3.5e-10 40.5 0.0 1.4e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY43426.1 - 1.6e-06 28.0 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY43426.1 - 3.4e-06 27.0 0.0 4.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY43426.1 - 0.00043 19.9 0.0 0.00091 18.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KIY43426.1 - 0.0036 16.7 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KIY43426.1 - 0.079 14.0 0.0 0.14 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain BTB PF00651.31 KIY43427.1 - 0.00038 20.6 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF2315 PF10231.9 KIY43429.1 - 2.4e-23 82.6 0.2 5.6e-23 81.3 0.2 1.6 1 1 0 1 1 1 1 Apoptogenic protein 1 DUF2040 PF09745.9 KIY43430.1 - 5.3e-38 129.8 24.1 5.3e-38 129.8 24.1 3.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) PRKG1_interact PF15898.5 KIY43430.1 - 0.0098 16.8 6.3 0.0098 16.8 6.3 3.5 3 1 0 3 3 3 1 cGMP-dependent protein kinase interacting domain DAGK_cat PF00781.24 KIY43431.1 - 2.3e-18 66.0 0.0 4.7e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Histone PF00125.24 KIY43432.1 - 1.1e-22 80.7 1.2 1.5e-22 80.4 1.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIY43432.1 - 3.3e-05 24.1 0.1 6.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIY43432.1 - 0.00034 21.1 0.0 0.00065 20.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KIY43432.1 - 0.03 14.3 0.1 0.035 14.2 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein MFS_1 PF07690.16 KIY43434.1 - 1.3e-30 106.6 54.5 5.3e-26 91.4 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DHHC PF01529.20 KIY43435.1 - 1e-26 93.6 11.7 1.9e-26 92.7 11.7 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF35_N PF12172.8 KIY43435.1 - 0.015 15.2 3.2 0.044 13.7 3.2 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Phage_holin_3_6 PF07332.11 KIY43435.1 - 4.9 7.2 5.0 21 5.2 0.2 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Fungal_trans PF04082.18 KIY43436.1 - 3.6e-19 68.8 0.0 6.6e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY43436.1 - 3.4e-10 39.9 3.7 3.4e-10 39.9 3.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-PHD-like PF15446.6 KIY43436.1 - 0.019 14.6 2.3 0.036 13.7 2.3 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain UPF0147 PF03685.13 KIY43436.1 - 0.087 12.9 0.1 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) CTP_transf_like PF01467.26 KIY43437.1 - 7e-08 32.8 0.0 4.7e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 Cytidylyltransferase-like TetR_C_3 PF08362.11 KIY43437.1 - 0.11 12.4 0.0 0.36 10.8 0.0 1.7 1 1 1 2 2 2 0 YcdC-like protein, C-terminal region UBA_4 PF14555.6 KIY43439.1 - 3.2e-10 39.7 0.0 5.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KIY43439.1 - 8e-07 29.2 0.0 3.2e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 UBX domain Gluconate_2-dh3 PF13618.6 KIY43439.1 - 0.081 13.2 0.5 0.19 12.0 0.5 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Nkap_C PF06047.11 KIY43440.1 - 8e-41 138.3 6.5 9.1e-41 138.1 6.5 1.0 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain TFIID-18kDa PF02269.16 KIY43441.1 - 1.7e-17 63.2 0.1 2e-17 63.0 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit SPACA9 PF15120.6 KIY43441.1 - 0.042 13.6 0.1 0.049 13.4 0.1 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Methyltransf_23 PF13489.6 KIY43442.1 - 1.4e-22 80.3 0.0 2.1e-22 79.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY43442.1 - 5.1e-21 75.1 0.0 1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY43442.1 - 1.7e-17 63.9 0.0 4.2e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY43442.1 - 3.2e-16 59.9 0.0 5.7e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY43442.1 - 2e-14 53.7 0.0 2.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIY43442.1 - 2e-08 33.9 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KIY43442.1 - 5.1e-06 25.6 0.0 8.6e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KIY43442.1 - 5.1e-06 26.0 0.0 7.5e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIY43442.1 - 1.8e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIY43442.1 - 8.4e-05 22.1 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KIY43442.1 - 0.00078 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 KIY43442.1 - 0.0047 16.1 0.0 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase TPMT PF05724.11 KIY43442.1 - 0.0091 15.7 0.0 0.063 12.9 0.0 2.0 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KIY43442.1 - 0.034 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KIY43442.1 - 0.035 13.7 0.1 0.074 12.6 0.1 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DUF4211 PF13926.6 KIY43443.1 - 1.6e-32 112.6 0.1 7.6e-32 110.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) ADH_zinc_N PF00107.26 KIY43444.1 - 6.4e-18 65.0 0.0 1.2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY43444.1 - 1e-07 31.6 0.2 3.2e-07 30.1 0.2 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIY43444.1 - 0.00019 22.5 0.0 0.00032 21.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KIY43444.1 - 0.0022 17.9 0.2 0.0022 17.9 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Syja_N PF02383.18 KIY43445.1 - 1.3e-90 304.0 0.0 1.8e-90 303.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KIY43445.1 - 4.1e-33 113.5 0.0 9.3e-33 112.4 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase Mem_trans PF03547.18 KIY43446.1 - 2.8e-21 75.4 1.5 3.6e-21 75.0 1.5 1.1 1 0 0 1 1 1 1 Membrane transport protein KcnmB2_inactiv PF09303.10 KIY43446.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 KCNMB2, ball and chain domain DUF3074 PF11274.8 KIY43447.1 - 3.3e-44 151.1 0.1 4.3e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.19 KIY43447.1 - 5.4e-05 22.7 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 START domain Ribosomal_L27 PF01016.19 KIY43448.1 - 1.3e-33 114.8 2.0 1.7e-33 114.4 2.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Skp1 PF01466.19 KIY43449.1 - 4e-29 100.5 0.4 7e-29 99.7 0.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIY43449.1 - 4.6e-23 81.2 0.2 1.6e-22 79.5 0.0 2.0 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 KIY43449.1 - 0.0064 16.7 0.0 0.28 11.4 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain mRNA_cap_enzyme PF01331.19 KIY43450.1 - 8.9e-50 169.2 0.1 1.7e-49 168.3 0.0 1.4 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KIY43450.1 - 1.2e-28 99.9 0.8 1.5e-28 99.5 0.1 1.6 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KIY43450.1 - 2.8e-11 43.5 0.0 6.8e-08 32.4 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DUF4732 PF15876.5 KIY43452.1 - 0.044 13.9 0.0 0.098 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4732) WD40 PF00400.32 KIY43452.1 - 0.22 12.4 6.3 1.2 10.1 0.0 4.4 7 0 0 7 7 7 0 WD domain, G-beta repeat Gln-synt_C PF00120.24 KIY43453.1 - 7e-70 235.7 0.0 3e-69 233.6 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain p450 PF00067.22 KIY43454.1 - 1.6e-55 188.7 0.0 1.9e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KIY43455.1 - 3.8e-21 75.3 1.3 6.4e-21 74.6 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY43455.1 - 3.8e-08 33.3 0.1 2.2e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Berberine and berberine like Glyco_hydro_7 PF00840.20 KIY43456.1 - 8.6e-33 113.7 12.6 1.2e-28 100.0 4.8 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 7 PTN_MK_N PF05196.13 KIY43456.1 - 3.3 8.0 6.9 1.1 9.5 1.5 2.6 2 1 1 3 3 3 0 PTN/MK heparin-binding protein family, N-terminal domain UbiA PF01040.18 KIY43457.1 - 3.6e-24 85.4 3.2 4.5e-24 85.1 3.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 KIY43458.1 - 2.1e-46 158.6 0.0 3.5e-46 157.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KIY43459.1 - 4.6e-57 193.6 0.0 8.1e-57 192.8 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY43459.1 - 3.6e-32 111.9 0.0 6e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY43459.1 - 0.00015 21.9 0.2 0.00042 20.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY43459.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY43459.1 - 0.014 14.5 0.0 0.043 12.9 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 KIY43459.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.25 KIY43460.1 - 1.7e-27 96.2 0.0 1.6e-22 79.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY43460.1 - 3e-16 59.7 0.0 6.8e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY43460.1 - 4.9e-10 39.6 0.0 6.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY43460.1 - 9.7e-07 28.5 0.0 1.8e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY43460.1 - 0.00024 20.6 0.0 0.0021 17.5 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIY43460.1 - 0.0034 17.3 0.1 0.0055 16.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ArenaCapSnatch PF17296.2 KIY43460.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Arenavirus cap snatching domain NAD_binding_4 PF07993.12 KIY43460.1 - 0.061 12.5 0.1 0.091 11.9 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein MBOAT_2 PF13813.6 KIY43461.1 - 1.4e-16 60.5 1.2 1.4e-16 60.5 1.2 1.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family p450 PF00067.22 KIY43463.1 - 2e-53 181.8 0.0 2.5e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KIY43464.1 - 2.1e-26 92.6 0.1 4.2e-22 78.6 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY43464.1 - 3.2e-14 53.0 0.0 1.3e-11 44.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY43464.1 - 4.5e-11 43.0 0.1 7e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY43464.1 - 3.7e-06 26.6 0.0 9.4e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY43464.1 - 3.8e-05 23.2 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIY43464.1 - 7.9e-05 22.6 0.2 0.00012 22.0 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY43464.1 - 0.0057 15.7 0.0 0.14 11.1 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family SMC_hinge PF06470.13 KIY43464.1 - 0.0084 16.4 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain NAD_binding_4 PF07993.12 KIY43464.1 - 0.058 12.5 0.0 0.62 9.2 0.1 2.0 2 0 0 2 2 2 0 Male sterility protein F420_oxidored PF03807.17 KIY43464.1 - 0.094 13.3 0.1 0.2 12.3 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ArenaCapSnatch PF17296.2 KIY43464.1 - 0.21 11.0 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain F-box-like PF12937.7 KIY43465.1 - 2e-05 24.4 7.3 2.8e-05 23.9 3.3 3.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY43465.1 - 0.66 9.9 6.6 9.7 6.2 0.0 3.7 3 1 0 3 3 3 0 F-box domain Lipase_3 PF01764.25 KIY43466.1 - 4.1e-07 30.0 0.0 1.1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY43466.1 - 0.001 19.7 0.6 0.0017 19.0 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY43466.1 - 0.002 17.8 0.1 0.0032 17.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 KIY43466.1 - 0.012 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 KIY43466.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Amidohydro_1 PF01979.20 KIY43467.1 - 6.6e-68 229.5 0.0 8.9e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIY43467.1 - 1.6e-10 41.0 0.0 1e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KIY43467.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase ELL PF10390.9 KIY43468.1 - 0.013 15.0 0.1 0.014 14.9 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Vir_act_alpha_C PF10400.9 KIY43468.1 - 0.029 15.0 0.3 0.053 14.2 0.3 1.5 1 0 0 1 1 1 0 Virulence activator alpha C-term zf-RING_2 PF13639.6 KIY43469.1 - 5.1e-10 39.5 10.0 9.8e-07 29.0 1.5 3.4 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 KIY43469.1 - 1.2e-08 34.6 0.3 3.3e-05 23.7 0.0 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY43469.1 - 2.6e-07 30.8 9.0 1.5e-06 28.4 0.2 2.9 3 1 0 3 3 2 2 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIY43469.1 - 1.3e-05 25.2 6.5 0.00013 21.9 0.7 3.2 2 2 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KIY43469.1 - 1.3e-05 24.8 7.7 0.003 17.3 0.5 3.4 3 0 0 3 3 3 2 RING-like zinc finger Zn_ribbon_17 PF17120.5 KIY43469.1 - 0.00013 21.5 0.2 0.00013 21.5 0.2 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KIY43469.1 - 0.00021 21.1 17.3 0.00022 21.0 1.9 3.9 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY43469.1 - 0.00035 20.5 10.2 0.00083 19.3 0.7 2.9 3 1 0 3 3 3 2 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIY43469.1 - 0.0028 17.7 1.4 0.0028 17.7 1.4 3.4 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KIY43469.1 - 0.038 13.9 6.2 0.03 14.2 1.5 2.6 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KIY43469.1 - 0.038 14.2 2.0 6.2 7.1 0.5 3.0 2 0 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KIY43469.1 - 0.083 13.0 0.6 0.24 11.5 0.6 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 KIY43469.1 - 0.11 12.4 6.4 0.068 13.0 0.5 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KIY43469.1 - 7.4 7.0 8.4 3.4 8.0 1.1 3.0 2 1 0 2 2 2 0 RING-like domain Pro_CA PF00484.19 KIY43470.1 - 2.1e-41 141.8 0.1 3.3e-41 141.2 0.1 1.3 1 1 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.20 KIY43470.1 - 0.062 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2147 PF09917.9 KIY43470.1 - 0.13 12.9 0.0 0.21 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) Exo_endo_phos PF03372.23 KIY43471.1 - 6.3e-07 29.1 0.0 3.2e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lamprin PF06403.11 KIY43471.1 - 0.033 14.2 1.1 0.078 12.9 1.1 1.5 1 0 0 1 1 1 0 Lamprin SRPRB PF09439.10 KIY43472.1 - 4.6e-19 68.5 0.0 6.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KIY43472.1 - 8e-09 35.2 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY43472.1 - 6.9e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY43472.1 - 2.9e-05 23.5 0.0 4.9e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KIY43472.1 - 0.00038 20.7 0.0 0.00075 19.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIY43472.1 - 0.011 15.3 0.0 0.65 9.5 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KIY43472.1 - 0.052 13.1 0.1 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KIY43472.1 - 0.056 13.7 0.0 0.58 10.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KIY43472.1 - 0.07 12.5 0.0 0.16 11.4 0.0 1.6 1 1 1 2 2 2 0 Bacterial TniB protein Parvo_NS1 PF01057.17 KIY43472.1 - 0.15 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Utp21 PF04192.12 KIY43473.1 - 8.3e-63 212.0 0.7 1.4e-62 211.3 0.7 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KIY43473.1 - 3.9e-14 52.7 0.0 0.00031 21.0 0.0 6.8 3 2 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY43473.1 - 1.6e-10 41.4 19.2 0.051 14.5 0.1 9.8 10 1 0 10 10 10 3 WD domain, G-beta repeat PQQ_2 PF13360.6 KIY43473.1 - 5.4e-06 26.2 0.1 2.3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 KIY43473.1 - 0.013 14.2 0.9 1.1 7.8 0.0 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Podoplanin PF05808.11 KIY43474.1 - 8e-05 22.8 4.0 0.00016 21.8 4.0 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 KIY43474.1 - 0.00011 22.1 4.4 0.00027 20.9 3.5 2.0 1 1 1 2 2 2 1 TMEM154 protein family CYYR1 PF10873.8 KIY43474.1 - 0.00014 22.4 0.4 0.00027 21.4 0.4 1.5 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 MGC-24 PF05283.11 KIY43474.1 - 0.00099 19.6 5.8 0.00099 19.6 5.8 1.8 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5305 PF17231.2 KIY43474.1 - 0.0037 16.7 1.1 0.0061 16.0 1.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Amnionless PF14828.6 KIY43474.1 - 0.0085 15.0 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 Amnionless DUF4690 PF15756.5 KIY43474.1 - 0.027 15.1 4.5 0.066 13.8 3.7 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Mid2 PF04478.12 KIY43474.1 - 0.032 14.1 0.4 0.062 13.1 0.4 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 KIY43474.1 - 0.036 13.5 1.3 0.14 11.6 1.3 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KIY43474.1 - 0.036 14.9 0.0 0.095 13.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3042 PF11240.8 KIY43474.1 - 0.091 12.8 0.5 0.21 11.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) TrbL PF04610.14 KIY43474.1 - 0.19 11.4 4.8 0.39 10.4 4.8 1.5 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein EssA PF10661.9 KIY43474.1 - 0.4 10.5 1.3 0.62 9.9 1.3 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Alpha_GJ PF03229.13 KIY43474.1 - 0.66 10.5 13.0 1.9 9.0 13.0 1.8 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF4231 PF14015.6 KIY43474.1 - 2 8.9 5.0 11 6.6 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 KIY43476.1 - 4.8e-26 91.5 38.2 4.5e-20 71.9 23.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Cofilin_ADF PF00241.20 KIY43477.1 - 3.1e-16 59.3 0.1 3.7e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Par3_HAL_N_term PF12053.8 KIY43477.1 - 0.046 13.9 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins Mannosyl_trans PF05007.13 KIY43478.1 - 2.9e-76 256.8 15.8 4.3e-76 256.2 15.8 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KIY43478.1 - 2.8e-10 39.8 18.3 7.8e-10 38.3 18.3 1.6 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Arf PF00025.21 KIY43479.1 - 1.2e-67 226.8 0.0 1.4e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIY43479.1 - 4.8e-10 39.1 0.0 1.2e-06 28.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIY43479.1 - 3.1e-09 36.5 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIY43479.1 - 6.7e-08 32.6 0.0 1.3e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KIY43479.1 - 1.2e-07 32.0 0.0 2.6e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIY43479.1 - 2.1e-06 27.5 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIY43479.1 - 8.6e-06 25.3 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY43479.1 - 0.03 13.9 0.0 0.56 9.7 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KIY43479.1 - 0.042 13.6 0.0 0.18 11.6 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KIY43479.1 - 0.13 11.8 0.0 4.3 6.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PemK_toxin PF02452.17 KIY43482.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system LIM PF00412.22 KIY43483.1 - 1.6e-13 50.7 22.5 7.8e-08 32.4 9.6 3.4 3 0 0 3 3 3 3 LIM domain Med16 PF11635.8 KIY43483.1 - 0.41 8.5 1.8 0.5 8.2 1.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 PolC_DP2 PF03833.13 KIY43483.1 - 1.7 6.4 5.1 2 6.1 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF563 PF04577.14 KIY43484.1 - 2.2e-07 31.3 0.0 4.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase PF00069.25 KIY43485.1 - 0.0011 18.4 0.0 0.65 9.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 KIY43485.1 - 0.0076 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 KIY43485.1 - 0.12 11.6 0.0 2.2 7.5 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase ERCC4 PF02732.15 KIY43487.1 - 3.7e-21 76.0 0.0 6.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain ATP_bind_1 PF03029.17 KIY43490.1 - 8.6e-74 248.3 0.0 1.1e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KIY43490.1 - 0.001 19.1 0.0 0.011 15.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY43490.1 - 0.0023 17.5 0.0 0.024 14.2 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KIY43490.1 - 0.0025 16.8 0.0 0.077 12.0 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 KIY43490.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.6 KIY43490.1 - 0.022 14.9 0.0 0.13 12.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KIY43490.1 - 0.045 13.5 0.0 2.3 8.0 0.0 2.7 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KIY43490.1 - 0.07 13.5 0.0 5.6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIY43490.1 - 0.15 12.0 0.0 25 4.7 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase PAPA-1 PF04795.12 KIY43490.1 - 0.21 12.4 0.6 0.34 11.7 0.6 1.2 1 0 0 1 1 1 0 PAPA-1-like conserved region HSP9_HSP12 PF04119.12 KIY43491.1 - 5e-23 81.3 10.1 5e-23 81.3 10.1 1.6 2 0 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.6 KIY43491.1 - 0.045 14.1 1.5 1.3 9.4 0.4 2.4 2 0 0 2 2 2 0 MT0933-like antitoxin protein Amino_oxidase PF01593.24 KIY43492.1 - 1.1e-25 90.9 0.0 1.4e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY43492.1 - 1.1e-09 38.4 0.3 2.2e-09 37.4 0.1 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY43492.1 - 2.1e-07 30.8 0.3 7.3e-07 29.1 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIY43492.1 - 0.0044 16.3 0.0 0.0092 15.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIY43492.1 - 0.062 12.5 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY43492.1 - 0.13 12.2 0.2 0.29 11.1 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIY43492.1 - 0.2 12.2 0.1 7.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Snf7 PF03357.21 KIY43493.1 - 6.5e-15 55.2 5.1 8.7e-15 54.7 5.1 1.2 1 0 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 KIY43493.1 - 0.0032 17.1 1.5 0.0032 17.1 1.5 1.9 1 1 0 2 2 2 1 PspA/IM30 family CdvA PF18822.1 KIY43493.1 - 0.028 14.2 3.3 0.37 10.6 2.5 2.7 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Syntaxin-6_N PF09177.11 KIY43493.1 - 0.27 11.8 5.9 39 4.9 0.1 3.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal SlyX PF04102.12 KIY43493.1 - 0.31 11.7 2.4 0.32 11.6 0.3 2.2 2 0 0 2 2 2 0 SlyX COG2 PF06148.11 KIY43493.1 - 0.82 9.8 2.9 1.1 9.4 0.4 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OTU PF02338.19 KIY43494.1 - 0.00033 21.2 0.0 0.00051 20.5 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Cys_Met_Meta_PP PF01053.20 KIY43495.1 - 2.1e-129 431.4 0.0 1.3e-128 428.8 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 KIY43495.1 - 0.00013 20.7 0.0 0.0002 20.0 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 KIY43495.1 - 0.0043 16.1 0.0 0.0066 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIY43495.1 - 0.0065 15.7 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DAP3 PF10236.9 KIY43496.1 - 4.4e-48 164.1 0.0 7.9e-48 163.2 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KIY43496.1 - 0.0009 19.7 0.1 0.0016 18.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KIY43496.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIY43496.1 - 0.045 14.1 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY43496.1 - 0.055 13.8 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIY43496.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 KIY43496.1 - 0.066 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KIY43496.1 - 0.092 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KIY43496.1 - 0.15 11.6 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KIY43496.1 - 0.16 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIY43496.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_D PF01813.17 KIY43497.1 - 3e-71 239.3 1.9 3.6e-71 239.1 1.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Dioxygenase_C PF00775.21 KIY43498.1 - 2.1e-11 43.6 0.0 3.8e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase WW PF00397.26 KIY43499.1 - 8.4e-09 35.4 5.3 8.4e-09 35.4 5.3 1.9 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 KIY43499.1 - 0.00032 20.8 7.7 0.00032 20.8 7.7 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Proteasome PF00227.26 KIY43500.1 - 1.8e-49 167.8 0.1 2.3e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L7Ae PF01248.26 KIY43501.1 - 1.4e-25 88.9 0.1 1.7e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KIY43501.1 - 0.0026 17.8 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KIY43501.1 - 0.0033 17.3 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain UQ_con PF00179.26 KIY43502.1 - 6.9e-48 161.9 0.1 7.7e-48 161.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY43502.1 - 0.0017 18.0 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KIY43502.1 - 0.28 11.5 1.8 0.49 10.7 1.8 1.7 1 1 0 1 1 1 0 RWD domain DUF5494 PF17598.2 KIY43504.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5494) Pkinase PF00069.25 KIY43505.1 - 1.4e-59 201.6 0.0 1.8e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43505.1 - 4e-28 98.4 0.0 5.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY43505.1 - 1.8e-08 34.1 0.0 3.8e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY43505.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY43505.1 - 0.0077 15.2 0.0 0.016 14.2 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY43505.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY43505.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Glyco_transf_22 PF03901.17 KIY43506.1 - 6.8e-90 302.3 21.6 8.1e-90 302.0 21.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family GTP_EFTU PF00009.27 KIY43507.1 - 9.8e-54 181.9 0.2 1.5e-53 181.3 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KIY43507.1 - 4.2e-42 142.6 0.4 9.2e-42 141.6 0.4 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KIY43507.1 - 1.4e-18 66.7 0.0 2.7e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIY43507.1 - 6.6e-10 39.2 0.2 2.1e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY43507.1 - 1.7e-06 28.1 0.1 3.7e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KIY43507.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 KIY43507.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 KIY43507.1 - 0.00021 21.3 0.0 0.00052 20.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 KIY43507.1 - 0.058 12.8 0.1 0.18 11.2 0.0 2.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KIY43507.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain cwf18 PF08315.12 KIY43508.1 - 3.3e-30 105.5 13.7 3.3e-30 105.5 13.7 1.8 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor SIR4_SID PF16991.5 KIY43508.1 - 0.13 12.3 1.1 0.18 11.8 1.1 1.3 1 0 0 1 1 1 0 Sir4 SID domain TRAM_LAG1_CLN8 PF03798.16 KIY43509.1 - 6e-18 65.3 14.3 6e-18 65.3 14.3 1.5 2 0 0 2 2 2 1 TLC domain IF-2B PF01008.17 KIY43510.1 - 2.8e-60 203.9 0.0 3.6e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family QSOX_Trx1 PF18108.1 KIY43510.1 - 0.0052 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 QSOX Trx-like domain Cyt_c_ox_IV PF12270.8 KIY43510.1 - 0.033 14.3 0.1 0.26 11.4 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF1931 PF09123.11 KIY43510.1 - 0.043 13.9 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) Pkinase_Tyr PF07714.17 KIY43511.1 - 1.6e-45 155.4 0.0 2.3e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY43511.1 - 3.4e-45 154.5 0.0 4.6e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SAP PF02037.27 KIY43511.1 - 3.1e-05 23.6 1.4 5.4e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 SAP domain DUF4035 PF13227.6 KIY43511.1 - 0.012 15.3 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) APH PF01636.23 KIY43511.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY43511.1 - 0.038 12.9 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIY43511.1 - 0.052 12.3 0.2 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase F-box_4 PF15966.5 KIY43512.1 - 0.022 14.6 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 F-box CPL PF08144.11 KIY43512.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 CPL (NUC119) domain DUF5596 PF18082.1 KIY43512.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Elongin_A PF06881.11 KIY43513.1 - 2.3e-22 79.5 1.0 3.3e-22 79.0 1.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A PRP21_like_P PF12230.8 KIY43513.1 - 0.024 14.5 0.2 0.033 14.1 0.2 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein AChE_tetra PF08674.10 KIY43513.1 - 0.084 12.6 0.7 0.22 11.2 0.7 1.7 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Gti1_Pac2 PF09729.9 KIY43514.1 - 8.2e-29 101.0 0.1 3e-27 95.9 0.2 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family Med18 PF09637.10 KIY43515.1 - 4.9e-07 29.9 0.0 6.3e-05 22.9 0.0 2.0 2 0 0 2 2 2 2 Med18 protein WD40 PF00400.32 KIY43516.1 - 2.3e-33 113.7 13.9 7.6e-08 32.9 0.0 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY43516.1 - 3.1e-08 33.8 0.6 1.3 9.3 0.1 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GLTT PF01744.20 KIY43516.1 - 0.17 11.7 2.8 4.5 7.1 0.7 2.4 2 0 0 2 2 2 0 GLTT repeat (6 copies) Myotub-related PF06602.14 KIY43517.1 - 2.2e-150 500.5 0.2 2.9e-150 500.1 0.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KIY43517.1 - 0.0024 17.7 0.0 0.0095 15.8 0.0 2.0 2 0 0 2 2 2 1 GRAM domain PH_TFIIH PF08567.11 KIY43517.1 - 0.02 15.2 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Y_phosphatase PF00102.27 KIY43517.1 - 0.082 12.5 0.1 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DSPc PF00782.20 KIY43517.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KIY43517.1 - 0.17 11.8 0.1 0.48 10.3 0.1 1.9 1 1 0 1 1 1 0 Tyrosine phosphatase family S-AdoMet_synt_C PF02773.16 KIY43518.1 - 7.3e-67 223.6 0.4 2.6e-66 221.8 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KIY43518.1 - 4e-47 159.4 0.0 6.7e-47 158.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KIY43518.1 - 6.2e-45 151.9 0.8 9.6e-45 151.3 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KIY43518.1 - 0.037 12.8 0.4 0.18 10.6 0.1 1.9 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Glyoxal_oxid_N PF07250.11 KIY43519.1 - 3.4e-35 121.4 0.0 2.5e-34 118.5 0.0 2.2 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIY43519.1 - 1.9e-23 82.6 0.0 6e-23 80.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) KH_8 PF17903.1 KIY43520.1 - 0.00061 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KIY43520.1 - 0.0038 17.0 0.9 0.0078 16.0 0.9 1.5 1 0 0 1 1 1 1 KH domain Kdo PF06293.14 KIY43521.1 - 0.024 14.0 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIY43521.1 - 0.099 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain BORCS8 PF10167.9 KIY43522.1 - 0.0079 16.1 0.2 0.024 14.6 0.0 1.9 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 8 DUF2096 PF09869.9 KIY43522.1 - 0.016 15.2 0.7 0.045 13.8 0.6 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) CLZ PF16526.5 KIY43522.1 - 0.056 13.8 6.2 0.18 12.2 3.9 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4349 PF14257.6 KIY43522.1 - 0.31 10.5 5.9 0.22 10.9 2.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) DUF445 PF04286.12 KIY43523.1 - 0.09 12.6 1.0 0.12 12.1 0.9 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF445) G-gamma PF00631.22 KIY43524.1 - 1.3e-23 82.8 0.1 1.4e-23 82.6 0.1 1.0 1 0 0 1 1 1 1 GGL domain G-gamma PF00631.22 KIY43525.1 - 2.6e-24 85.0 0.1 2.9e-24 84.8 0.1 1.0 1 0 0 1 1 1 1 GGL domain Trp_syntA PF00290.20 KIY43526.1 - 3e-85 285.2 0.4 4.2e-85 284.7 0.4 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KIY43526.1 - 3.9e-45 154.5 0.2 7.5e-45 153.6 0.2 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 KIY43526.1 - 0.0024 17.4 0.1 0.0064 16.0 0.1 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KIY43526.1 - 0.019 14.4 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Brix PF04427.18 KIY43527.1 - 5.5e-37 127.7 0.0 7.5e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain MPS2 PF17060.5 KIY43529.1 - 0.028 13.7 0.4 0.043 13.1 0.4 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Casc1_N PF15927.5 KIY43529.1 - 0.038 13.7 4.4 0.067 12.9 4.4 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Asparaginase PF00710.20 KIY43530.1 - 2.4e-58 196.9 0.0 1.3e-57 194.5 0.0 2.0 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KIY43530.1 - 5.5e-28 97.5 0.0 1.1e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 KIY43530.1 - 3.3e-13 49.8 1.5 6.1e-08 33.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY43530.1 - 1.5e-11 44.7 0.3 8.9e-11 42.2 0.3 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY43530.1 - 2.8e-10 40.3 0.1 3.3e-07 30.4 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY43530.1 - 1.6e-09 37.8 1.9 0.0019 18.5 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KIY43530.1 - 2.8e-09 36.4 0.3 0.017 15.6 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat A_deaminase PF00962.22 KIY43531.1 - 5.2e-25 88.5 0.1 1.2e-20 74.1 0.0 2.8 2 1 0 2 2 2 2 Adenosine/AMP deaminase SNF2_N PF00176.23 KIY43532.1 - 2.5e-65 220.5 1.8 5.1e-65 219.5 0.6 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 KIY43532.1 - 3.7e-39 133.3 1.6 1.3e-38 131.5 0.5 2.7 2 0 0 2 2 1 1 SLIDE HAND PF09110.11 KIY43532.1 - 3.5e-29 101.8 0.3 3.5e-29 101.8 0.3 2.9 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KIY43532.1 - 4e-19 69.0 0.0 2.7e-17 63.1 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY43532.1 - 2.4e-09 37.4 0.0 1.1e-08 35.2 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIY43532.1 - 6.3e-06 25.6 0.0 1.8e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KIY43532.1 - 7.9e-05 22.5 0.0 0.00024 20.9 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KIY43532.1 - 0.00019 21.2 0.2 0.0014 18.3 0.0 2.4 1 1 0 2 2 2 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 KIY43532.1 - 0.00036 20.2 0.4 0.0013 18.4 0.4 1.9 1 0 0 1 1 1 1 DEAD_2 DBINO PF13892.6 KIY43532.1 - 0.003 17.9 1.9 0.003 17.9 1.9 3.5 4 0 0 4 4 4 1 DNA-binding domain AAA_14 PF13173.6 KIY43532.1 - 0.057 13.5 0.1 0.21 11.6 0.1 2.1 1 0 0 1 1 1 0 AAA domain Methyltransf_11 PF08241.12 KIY43533.1 - 9.3e-15 55.1 0.0 1.4e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY43533.1 - 7.5e-11 42.6 0.0 1.3e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY43533.1 - 9.4e-06 26.3 0.0 1.8e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY43533.1 - 0.0025 17.7 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY43533.1 - 0.02 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIY43533.1 - 0.029 14.2 0.0 0.18 11.6 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain PUF PF00806.19 KIY43535.1 - 5.6e-66 214.7 7.0 2.3e-09 36.4 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 KIY43535.1 - 0.0023 17.8 0.1 0.78 9.6 0.0 4.0 4 1 1 5 5 5 1 Single Cache domain 2 Kinesin PF00225.23 KIY43537.1 - 1.8e-111 372.3 0.6 1.8e-111 372.3 0.6 2.6 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KIY43537.1 - 1.4e-28 99.7 0.0 6.3e-28 97.6 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding DUF465 PF04325.13 KIY43537.1 - 0.00043 20.2 1.0 0.00043 20.2 1.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF465) TACC_C PF05010.14 KIY43537.1 - 2.2 8.0 61.4 1.8 8.3 18.5 3.4 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DASH_Dam1 PF08653.10 KIY43537.1 - 2.2 8.1 14.1 8 6.4 0.3 5.4 4 0 0 4 4 4 0 DASH complex subunit Dam1 Sox_N PF12444.8 KIY43537.1 - 3.4 8.9 5.9 8.1 7.7 0.0 3.7 3 0 0 3 3 3 0 Sox developmental protein N terminal RolB_RolC PF02027.17 KIY43537.1 - 6.8 6.3 6.0 1.2 8.7 0.6 2.2 2 0 0 2 2 2 0 RolB/RolC glucosidase family LMSTEN PF07988.12 KIY43539.1 - 0.076 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 LMSTEN motif ApbA_C PF08546.11 KIY43540.1 - 0.089 13.0 1.4 0.18 12.0 1.4 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal MFS_1 PF07690.16 KIY43541.1 - 2.1e-35 122.3 33.3 2.1e-35 122.3 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY43541.1 - 1.1e-12 47.6 7.6 6.4e-12 45.1 8.2 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIY43541.1 - 8.9e-05 21.1 2.1 0.00013 20.5 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_transf_15 PF01793.16 KIY43542.1 - 6.3e-124 413.5 9.0 7.6e-124 413.2 9.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 KIY43542.1 - 0.054 13.8 0.4 0.099 12.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Porin_3 PF01459.22 KIY43543.1 - 2.5e-77 260.0 0.9 2.9e-77 259.8 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF3835 PF12927.7 KIY43544.1 - 0.00082 20.2 1.2 0.00082 20.2 1.2 5.4 7 0 0 7 7 7 2 Domain of unknown function (DUF3835) Talin_middle PF09141.10 KIY43544.1 - 0.34 10.9 2.8 1.7 8.7 0.7 2.4 2 0 0 2 2 2 0 Talin, middle domain RRF PF01765.19 KIY43544.1 - 0.8 9.6 4.6 1.9 8.4 4.6 1.6 1 0 0 1 1 1 0 Ribosome recycling factor Cytomega_UL20A PF05984.12 KIY43544.1 - 1.4 9.3 4.0 1.1 9.5 0.5 2.7 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein GST_C_6 PF17171.4 KIY43545.1 - 5e-15 55.1 0.0 9.4e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY43545.1 - 9.4e-05 23.1 0.0 0.00017 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KIY43545.1 - 0.002 18.1 0.0 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KIY43545.1 - 0.031 14.6 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Vps54 PF07928.12 KIY43546.1 - 4.5e-52 176.0 2.5 1.2e-51 174.7 2.5 1.8 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 KIY43546.1 - 2.1e-06 27.2 0.0 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KIY43546.1 - 0.00013 21.8 2.4 0.00018 21.4 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DEAD PF00270.29 KIY43546.1 - 0.086 12.6 0.6 0.25 11.1 0.4 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase Occludin_ELL PF07303.13 KIY43546.1 - 0.15 12.8 4.9 3.1 8.6 0.1 3.1 3 0 0 3 3 3 0 Occludin homology domain DUF1713 PF08213.11 KIY43547.1 - 1.9e-06 27.7 25.8 3e-06 27.0 25.8 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) KH_1 PF00013.29 KIY43548.1 - 1.8e-44 149.4 6.8 2.9e-16 59.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KIY43548.1 - 4.4e-15 55.3 5.7 4.7e-05 23.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KIY43548.1 - 7.9e-06 25.7 2.2 0.074 12.9 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KIY43548.1 - 0.0011 19.0 6.1 0.26 11.4 0.2 3.5 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KIY43548.1 - 0.11 12.5 0.0 3.2 7.8 0.0 2.8 3 0 0 3 3 3 0 KH-like RNA-binding domain Sec16_C PF12931.7 KIY43549.1 - 4.7e-82 276.0 0.0 6.4e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KIY43549.1 - 1.4e-23 83.7 0.0 2.5e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Ribosomal_L26 PF16906.5 KIY43550.1 - 8.8e-36 122.2 4.4 1.2e-35 121.8 4.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KIY43550.1 - 3.1e-09 36.5 4.2 3.1e-09 36.5 4.2 1.8 2 0 0 2 2 2 1 KOW motif Methyltrans_RNA PF04452.14 KIY43550.1 - 0.14 11.5 0.2 0.15 11.4 0.2 1.1 1 0 0 1 1 1 0 RNA methyltransferase SdpI PF13630.6 KIY43552.1 - 2.8 8.1 8.2 0.23 11.6 0.3 2.5 2 0 0 2 2 2 0 SdpI/YhfL protein family ING PF12998.7 KIY43553.1 - 9.2e-11 42.2 1.3 9.2e-11 42.2 1.3 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding ABC_tran_CTD PF16326.5 KIY43553.1 - 0.0077 16.5 1.5 3.1 8.1 0.1 2.7 1 1 0 2 2 2 2 ABC transporter C-terminal domain HOOK PF05622.12 KIY43553.1 - 0.021 13.0 0.4 0.031 12.5 0.4 1.2 1 0 0 1 1 1 0 HOOK protein Cep57_MT_bd PF06657.13 KIY43553.1 - 0.038 14.4 0.8 0.12 12.8 0.8 1.9 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 AKNA PF12443.8 KIY43553.1 - 0.16 12.6 0.3 0.16 12.6 0.3 2.7 3 0 0 3 3 3 0 AT-hook-containing transcription factor Trimer_CC PF08954.11 KIY43553.1 - 0.34 10.5 3.1 1.7 8.3 3.1 2.2 1 0 0 1 1 1 0 Trimerisation motif PHD_2 PF13831.6 KIY43553.1 - 0.45 10.1 2.5 0.79 9.3 2.5 1.4 1 0 0 1 1 1 0 PHD-finger OST3_OST6 PF04756.13 KIY43554.1 - 1.1e-89 300.6 0.0 1.3e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KIY43554.1 - 0.00028 20.8 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin VKOR PF07884.14 KIY43554.1 - 1.2 9.3 8.8 0.15 12.2 1.5 2.2 2 0 0 2 2 2 0 Vitamin K epoxide reductase family MFS_1 PF07690.16 KIY43555.1 - 4.2e-39 134.5 27.6 6.1e-39 133.9 27.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PGPGW PF09656.10 KIY43555.1 - 0.74 9.4 4.5 1.2 8.7 0.3 2.7 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) Peptidase_A8 PF01252.18 KIY43555.1 - 1.7 8.9 7.9 6.5 7.0 0.2 3.2 2 1 1 3 3 3 0 Signal peptidase (SPase) II DUF726 PF05277.12 KIY43556.1 - 5.3e-86 288.6 1.3 8.6e-86 288.0 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.7 KIY43556.1 - 0.054 14.1 0.4 0.054 14.1 0.4 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3040 PF11239.8 KIY43556.1 - 5.5 7.3 8.3 17 5.7 6.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) SET PF00856.28 KIY43557.1 - 1.7e-13 51.3 0.0 3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KIY43557.1 - 1.1e-09 38.2 18.0 1.1e-09 38.2 18.0 2.7 3 0 0 3 3 3 1 MYND finger LEA_2 PF03168.13 KIY43558.1 - 0.00023 21.6 0.0 0.00039 20.9 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Vac7 PF12751.7 KIY43558.1 - 0.0076 15.7 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF1356 PF07092.12 KIY43558.1 - 0.039 13.2 0.8 0.057 12.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) MFS_1 PF07690.16 KIY43560.1 - 1.3e-43 149.3 43.4 1.6e-42 145.7 44.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY43560.1 - 3.1e-20 72.2 13.5 4.4e-20 71.6 13.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIY43560.1 - 1.3e-12 47.3 30.2 1.4e-12 47.2 16.6 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3185 PF11381.8 KIY43560.1 - 1.1 9.3 9.0 47 4.1 1.1 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3185) Insulin_TMD PF17870.1 KIY43560.1 - 1.9 8.6 6.7 4.3 7.5 0.0 3.9 4 0 0 4 4 4 0 Insulin receptor trans-membrane segment Vac_ImportDeg PF09783.9 KIY43561.1 - 1.5e-52 177.6 0.0 8.7e-47 158.9 0.0 2.0 2 0 0 2 2 2 2 Vacuolar import and degradation protein INTAP PF16617.5 KIY43561.1 - 0.016 15.5 1.6 1.9 8.8 1.3 2.2 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region JmjC PF02373.22 KIY43562.1 - 1.8e-11 44.4 0.3 9.3e-11 42.2 0.1 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cu-oxidase_3 PF07732.15 KIY43564.1 - 6.9e-28 97.1 0.2 1.9e-27 95.6 0.2 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY43564.1 - 1.1e-26 93.2 8.2 8.4e-21 74.2 0.3 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KIY43564.1 - 2.9e-16 60.0 0.0 7.6e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase NPR2 PF06218.11 KIY43565.1 - 2.8e-98 329.5 7.0 2.2e-78 264.0 8.8 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Baculo_p74 PF04583.12 KIY43565.1 - 0.099 12.1 0.1 4.8 6.6 0.1 2.2 2 0 0 2 2 2 0 Baculoviridae p74 conserved region ThiF PF00899.21 KIY43566.1 - 3.4e-64 216.5 0.0 4.9e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KIY43566.1 - 9e-26 89.8 1.2 1.5e-25 89.2 1.2 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KIY43566.1 - 0.0055 16.8 0.2 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KIY43566.1 - 0.025 14.2 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KIY43566.1 - 0.045 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 KIY43566.1 - 0.11 13.1 0.2 0.33 11.6 0.2 1.8 1 0 0 1 1 1 0 PglD N-terminal domain Ecm33 PF12454.8 KIY43566.1 - 0.16 12.1 2.8 0.33 11.1 2.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein ApbA PF02558.16 KIY43566.1 - 0.18 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UBA_e1_thiolCys PF10585.9 KIY43566.1 - 0.23 11.3 0.1 22 4.9 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site RTC PF01137.21 KIY43567.1 - 5.4e-58 195.8 0.0 6.2e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KIY43567.1 - 1.4e-37 128.3 0.0 2.4e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ras PF00071.22 KIY43568.1 - 3e-50 170.0 0.0 3.6e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY43568.1 - 3.1e-30 104.9 0.0 4.7e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY43568.1 - 4.2e-10 39.4 0.0 5.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY43568.1 - 0.00025 20.5 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY43568.1 - 0.0014 18.6 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KIY43568.1 - 0.0063 15.7 1.8 1.3 8.1 0.3 2.6 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.22 KIY43568.1 - 0.018 15.4 0.1 0.14 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 KIY43568.1 - 0.026 14.0 0.2 0.044 13.2 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KIY43568.1 - 0.028 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF5118 PF17162.4 KIY43568.1 - 0.037 13.8 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) AAA_24 PF13479.6 KIY43568.1 - 0.053 13.2 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIY43568.1 - 0.055 13.4 0.1 6.5 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KIY43568.1 - 0.068 13.5 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KIY43568.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIY43568.1 - 0.12 12.5 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain STAS PF01740.21 KIY43568.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain Septin PF00735.18 KIY43568.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin Glyco_hydro81C PF17652.1 KIY43569.1 - 2.3e-69 234.3 5.8 4.2e-69 233.4 5.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KIY43569.1 - 3.2e-28 98.8 3.5 4e-28 98.5 1.8 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Pkinase PF00069.25 KIY43570.1 - 2e-27 96.2 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43570.1 - 2.9e-13 49.7 0.0 4.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY43570.1 - 3e-08 32.9 0.0 4.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY43570.1 - 0.075 12.9 0.0 7.4 6.4 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cofilin_ADF PF00241.20 KIY43571.1 - 8.6e-34 115.9 0.0 4e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PNP_UDP_1 PF01048.20 KIY43572.1 - 1.1e-34 119.7 0.0 1.3e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Laminin_II PF06009.12 KIY43573.1 - 0.13 12.3 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Laminin Domain II CoA_trans PF01144.23 KIY43574.1 - 5.3e-91 303.8 1.8 2.1e-51 174.4 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KIY43574.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain FYVE PF01363.21 KIY43575.1 - 1.8e-17 63.3 1.2 3e-17 62.5 1.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 KIY43575.1 - 6.1e-16 57.9 2.3 2.8e-15 55.7 2.3 2.3 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE_2 PF02318.16 KIY43575.1 - 0.018 15.3 0.8 0.069 13.4 0.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C2HC5 PF06221.13 KIY43575.1 - 0.028 14.4 6.9 0.028 14.4 6.9 1.8 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Occludin_ELL PF07303.13 KIY43575.1 - 0.068 13.9 3.2 0.64 10.8 1.1 2.5 2 0 0 2 2 2 0 Occludin homology domain DUF3829 PF12889.7 KIY43575.1 - 0.21 11.1 1.4 0.39 10.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Mod_r PF07200.13 KIY43575.1 - 0.38 10.9 8.6 0.84 9.7 0.6 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein OrfB_Zn_ribbon PF07282.11 KIY43575.1 - 0.42 10.6 2.0 1 9.4 2.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_UBOX PF13445.6 KIY43575.1 - 5.3 7.2 14.4 2.8 8.0 10.0 2.6 2 1 0 2 2 2 0 RING-type zinc-finger OGG_N PF07934.12 KIY43576.1 - 1e-31 109.5 0.0 2.4e-31 108.3 0.0 1.6 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KIY43576.1 - 3.2e-16 59.7 0.0 5.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIY43576.1 - 0.039 13.8 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RPAP3_C PF13877.6 KIY43577.1 - 3.9e-16 59.4 0.0 5.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 FRG1 PF06229.12 KIY43578.1 - 1.2e-24 87.1 0.0 1.8e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KIY43578.1 - 0.0033 17.6 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 Fascin domain PS-DH PF14765.6 KIY43579.1 - 0.22 10.7 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Polyketide synthase dehydratase NAD_binding_7 PF13241.6 KIY43581.1 - 1.3e-27 96.2 0.0 2.3e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KIY43581.1 - 3.4e-21 74.6 0.4 7.6e-21 73.5 0.4 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KIY43581.1 - 1.3e-07 30.9 0.0 1.3e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central TrkA_N PF02254.18 KIY43581.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KIY43581.1 - 0.043 14.1 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Torus PF16131.5 KIY43582.1 - 3e-09 37.5 0.3 6e-09 36.6 0.3 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KIY43582.1 - 6.4e-06 26.0 3.5 2.3e-05 24.3 3.5 2.0 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KIY43582.1 - 0.00019 21.2 3.8 0.00059 19.7 3.8 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIY43582.1 - 0.0035 17.1 3.0 0.01 15.7 3.0 1.9 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KIY43582.1 - 0.0045 17.4 2.0 0.012 16.0 2.0 1.8 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger RRM_1 PF00076.22 KIY43582.1 - 0.0072 16.1 0.0 0.02 14.7 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 KIY43582.1 - 0.0098 16.1 0.3 0.032 14.4 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger containing family LUC7 PF03194.15 KIY43583.1 - 6.4e-70 235.7 5.7 8.3e-70 235.3 5.7 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Phlebovirus_NSM PF07246.11 KIY43583.1 - 0.072 12.4 0.5 0.11 11.9 0.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M UCH PF00443.29 KIY43585.1 - 2.1e-36 125.8 0.5 4.5e-36 124.7 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY43585.1 - 1e-16 61.4 2.5 5.3e-16 59.1 0.6 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KIY43585.1 - 1.3e-05 24.9 0.1 2.9e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Noelin-1 PF12308.8 KIY43585.1 - 0.093 12.7 1.0 0.34 10.9 0.2 2.4 3 0 0 3 3 3 0 Neurogenesis glycoprotein TAFII55_N PF04658.13 KIY43586.1 - 6.1e-57 191.8 2.6 2.7e-56 189.7 0.2 2.4 2 0 0 2 2 2 1 TAFII55 protein conserved region BUD22 PF09073.10 KIY43586.1 - 0.0098 15.3 22.0 0.016 14.5 22.0 1.5 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 KIY43586.1 - 0.041 12.1 29.8 0.061 11.5 29.8 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KIY43586.1 - 0.34 10.2 22.0 0.73 9.1 22.0 1.6 1 0 0 1 1 1 0 NOA36 protein Ribosomal_S13 PF00416.22 KIY43586.1 - 2.1 8.8 5.1 8.9 6.7 3.0 2.5 3 0 0 3 3 3 0 Ribosomal protein S13/S18 CDC45 PF02724.14 KIY43586.1 - 4.6 5.4 21.2 7.3 4.8 21.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KIY43586.1 - 5.2 6.4 27.8 8.7 5.7 27.8 1.4 1 0 0 1 1 1 0 SDA1 Gaa1 PF04114.14 KIY43587.1 - 4.8e-103 345.8 5.8 7.5e-102 341.9 5.8 2.0 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Ank_3 PF13606.6 KIY43588.1 - 6.4e-12 44.6 0.0 0.00013 22.2 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KIY43588.1 - 5.5e-11 42.5 0.1 2.8e-08 33.9 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY43588.1 - 6.4e-11 42.7 0.0 9.1e-10 39.0 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY43588.1 - 8e-11 42.2 0.0 4.1e-10 40.0 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KIY43588.1 - 3.4e-05 24.1 0.0 0.45 11.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Erythro_esteras PF05139.14 KIY43588.1 - 0.029 14.2 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Erythromycin esterase BCS1_N PF08740.11 KIY43589.1 - 1.3e-38 132.9 2.4 1.7e-38 132.5 2.4 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KIY43589.1 - 2.7e-17 63.4 0.0 4.4e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY43589.1 - 0.00014 22.3 0.1 0.002 18.6 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KIY43589.1 - 0.0021 17.7 0.0 0.0059 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KIY43589.1 - 0.003 16.8 0.0 0.0061 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KIY43589.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY43589.1 - 0.0086 15.9 0.2 0.021 14.7 0.2 1.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KIY43589.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIY43589.1 - 0.022 14.8 0.0 0.043 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KIY43589.1 - 0.022 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIY43589.1 - 0.047 13.6 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KIY43589.1 - 0.069 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIY43589.1 - 0.081 13.5 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIY43589.1 - 0.087 13.3 0.0 0.22 12.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KIY43589.1 - 0.11 12.7 0.0 0.37 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 KIY43589.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Viral_helicase1 PF01443.18 KIY43589.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KIY43589.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KIY43589.1 - 0.22 10.9 0.0 0.51 9.6 0.0 1.5 2 0 0 2 2 2 0 KaiC Ribosomal_S13 PF00416.22 KIY43590.1 - 4e-16 59.6 0.0 3.9e-07 30.5 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 KIY43590.1 - 0.0012 17.7 0.0 0.0031 16.4 0.0 1.6 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DNA_pol_lambd_f PF10391.9 KIY43590.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Pkinase PF00069.25 KIY43591.1 - 5.2e-53 180.1 0.0 6.1e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43591.1 - 4.3e-20 72.1 0.0 1.1e-19 70.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY43591.1 - 4.1e-09 36.2 0.0 4.5e-08 32.7 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KIY43591.1 - 0.0007 19.6 0.0 0.0038 17.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY43591.1 - 0.0009 18.1 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY43591.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY43591.1 - 0.015 15.0 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NMT_C PF02799.15 KIY43592.1 - 3.2e-82 275.1 0.0 7.7e-82 273.9 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KIY43592.1 - 7.7e-74 246.9 0.0 1.2e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF4691 PF15762.5 KIY43592.1 - 0.014 15.6 2.3 0.023 14.9 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) Acetyltransf_9 PF13527.7 KIY43592.1 - 0.025 14.7 0.0 0.093 12.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RuvA_C PF07499.13 KIY43592.1 - 0.028 14.9 0.2 0.11 13.0 0.0 2.1 1 1 1 2 2 2 0 RuvA, C-terminal domain Acetyltransf_1 PF00583.25 KIY43592.1 - 0.035 14.3 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CCDC106 PF15794.5 KIY43592.1 - 0.95 9.1 5.5 1.4 8.6 5.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 BUD22 PF09073.10 KIY43592.1 - 1.2 8.4 9.8 1.7 7.9 9.8 1.1 1 0 0 1 1 1 0 BUD22 Tom37 PF10568.9 KIY43593.1 - 3e-20 72.8 0.0 6.7e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KIY43593.1 - 2.4e-11 43.2 0.1 4.8e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY43593.1 - 3.6e-05 24.4 0.0 5.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 KIY43593.1 - 9.6e-05 22.5 0.2 0.02 15.1 0.0 2.4 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY43593.1 - 0.0001 22.2 0.2 0.00037 20.5 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF4169 PF13770.6 KIY43593.1 - 0.17 12.2 1.4 0.26 11.6 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) Peptidase_S10 PF00450.22 KIY43594.1 - 7.6e-67 226.5 0.1 1.1e-66 225.9 0.1 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Exo_endo_phos PF03372.23 KIY43595.1 - 1.5e-19 70.5 0.0 1.8e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WBS_methylT PF12589.8 KIY43596.1 - 1.5e-23 83.3 9.0 2.3e-23 82.7 9.0 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KIY43596.1 - 2.9e-09 37.4 0.0 6.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY43596.1 - 2.3e-07 31.4 0.0 4.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY43596.1 - 7.3e-05 23.4 0.0 0.00023 21.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY43596.1 - 0.00066 19.6 0.0 0.00093 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY43596.1 - 0.0083 15.9 0.0 0.012 15.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KIY43596.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Rrn6 PF10214.9 KIY43598.1 - 6.7e-10 38.2 0.5 3.2e-08 32.6 0.0 3.2 4 1 0 4 4 4 1 RNA polymerase I-specific transcription-initiation factor FliS PF02561.14 KIY43598.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FliS Ribosomal_L3 PF00297.22 KIY43599.1 - 8.6e-19 67.7 0.8 4.8e-17 62.0 0.3 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Mito_carr PF00153.27 KIY43600.1 - 1.9e-41 139.9 0.4 2.8e-14 52.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Cpn60_TCP1 PF00118.24 KIY43601.1 - 5.4e-147 490.4 10.1 6e-147 490.2 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.16 KIY43602.1 - 4.4e-30 104.8 29.7 4.4e-30 104.8 29.7 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY43602.1 - 2e-09 36.8 18.7 9.9e-09 34.6 18.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter CLTH PF10607.9 KIY43605.1 - 4.3e-15 55.9 0.0 6.2e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIY43605.1 - 0.15 12.1 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 LisH Aldedh PF00171.22 KIY43606.1 - 1.9e-122 409.1 0.0 2.2e-122 408.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IATP PF04568.12 KIY43607.1 - 0.00078 19.8 0.5 0.001 19.4 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Cellulase PF00150.18 KIY43608.1 - 5.7e-11 42.4 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF669 PF05037.13 KIY43609.1 - 0.11 12.6 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Pectate_lyase_3 PF12708.7 KIY43610.1 - 5.7e-93 310.7 16.6 5.3e-83 278.1 4.5 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIY43610.1 - 2.4e-06 27.2 0.5 0.017 14.8 0.0 3.0 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 KIY43610.1 - 0.00021 21.2 6.2 0.00021 21.2 6.2 2.8 3 1 0 3 3 3 1 Right handed beta helix region 2OG-FeII_Oxy_2 PF13532.6 KIY43611.1 - 2.7e-21 76.6 0.0 3.4e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GTP_EFTU PF00009.27 KIY43612.1 - 1.1e-33 116.4 4.7 1.9e-32 112.4 3.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KIY43612.1 - 1.5e-26 92.6 0.4 4.8e-26 90.9 0.4 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KIY43612.1 - 8.5e-08 32.3 0.2 2e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIY43612.1 - 6.1e-05 22.5 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIY43612.1 - 0.00073 19.5 0.5 0.53 10.2 0.0 2.6 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU_D2 PF03144.25 KIY43612.1 - 0.0011 19.3 2.0 0.18 12.2 0.4 3.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 KIY43612.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIY43612.1 - 0.0018 17.8 0.0 0.0041 16.6 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 KIY43612.1 - 0.0029 16.7 1.0 0.007 15.4 0.6 1.8 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 KIY43612.1 - 0.0037 17.0 0.2 0.043 13.6 0.2 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Acetyltransf_13 PF13880.6 KIY43613.1 - 2.2e-18 66.0 0.0 4.2e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KIY43613.1 - 2.6e-08 33.5 0.2 4.6e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KIY43613.1 - 0.0052 17.2 0.0 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY43613.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY43613.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KIY43613.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CDC45 PF02724.14 KIY43614.1 - 3.7e-215 716.0 0.0 4.4e-215 715.7 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Forkhead PF00250.18 KIY43617.1 - 4.9e-20 71.6 0.0 5.1e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain SCAB-ABD PF16711.5 KIY43617.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein DUF3740 PF12548.8 KIY43619.1 - 0.03 14.8 3.0 0.056 13.9 3.0 1.4 1 0 0 1 1 1 0 Sulfatase protein HSA PF07529.13 KIY43620.1 - 9.9e-14 51.4 0.9 9.9e-14 51.4 0.9 3.6 3 0 0 3 3 3 1 HSA SMI1_KNR4 PF09346.10 KIY43621.1 - 5.6e-24 85.0 0.0 1e-23 84.2 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DPBB_1 PF03330.18 KIY43622.1 - 2.3e-05 24.6 0.8 0.00037 20.7 0.8 2.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIY43622.1 - 8.7e-05 22.4 0.6 0.00014 21.7 0.6 1.4 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.21 KIY43622.1 - 0.00048 20.1 0.6 0.00092 19.2 0.6 1.5 1 0 0 1 1 1 1 Pollen allergen DUF1364 PF07102.12 KIY43622.1 - 0.081 12.8 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) GATase_2 PF00310.21 KIY43623.1 - 1.8e-172 573.8 0.0 2.4e-172 573.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KIY43623.1 - 2.4e-155 517.2 0.4 3.6e-155 516.6 0.0 1.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KIY43623.1 - 1.1e-111 372.8 0.0 7.5e-110 366.8 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KIY43623.1 - 3.5e-87 290.9 4.5 5.7e-87 290.2 4.5 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KIY43623.1 - 9e-23 80.9 0.0 4.6e-22 78.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KIY43623.1 - 3.3e-22 78.4 0.1 6.7e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DAO PF01266.24 KIY43623.1 - 4.6e-08 33.0 0.2 0.003 17.2 0.0 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY43623.1 - 5.9e-08 32.8 0.0 2.1e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY43623.1 - 2.2e-07 30.5 0.5 0.00096 18.5 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY43623.1 - 4.9e-07 30.2 0.1 0.00034 21.1 0.0 3.3 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY43623.1 - 5.3e-05 22.1 1.6 6.7e-05 21.8 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FMN_dh PF01070.18 KIY43623.1 - 0.00056 19.0 2.6 0.0043 16.1 1.0 2.8 3 0 0 3 3 3 1 FMN-dependent dehydrogenase Amino_oxidase PF01593.24 KIY43623.1 - 0.00058 19.3 0.0 0.00099 18.5 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KIY43623.1 - 0.0042 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KIY43623.1 - 0.0056 15.8 0.1 0.0056 15.8 0.1 2.1 2 0 0 2 2 1 1 FAD binding domain Thi4 PF01946.17 KIY43623.1 - 0.009 15.3 1.5 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 KIY43623.1 - 0.0094 15.3 0.3 0.54 9.5 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KIY43623.1 - 0.0097 16.0 0.9 5.2 7.1 0.1 2.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_oxidored PF12831.7 KIY43623.1 - 0.011 15.1 1.2 0.013 14.9 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIY43623.1 - 0.019 15.4 0.8 1.5 9.3 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KIY43623.1 - 0.11 11.8 0.4 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIY43623.1 - 0.21 11.4 0.1 0.49 10.3 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KIY43623.1 - 0.56 9.2 3.6 2.4 7.1 0.1 3.1 2 1 1 3 3 3 0 Glucose inhibited division protein A zf-Mss51 PF13824.6 KIY43624.1 - 7.9e-23 80.3 14.2 1.6e-22 79.3 14.2 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 CHORD PF04968.12 KIY43625.1 - 5.1e-36 123.2 6.3 3.2e-20 72.6 1.5 2.7 2 1 0 2 2 2 2 CHORD CS PF04969.16 KIY43625.1 - 1e-15 58.5 0.6 2.1e-15 57.5 0.4 1.6 2 0 0 2 2 2 1 CS domain Mito_carr PF00153.27 KIY43626.1 - 6.6e-12 45.2 0.0 0.00073 19.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KIY43627.1 - 9.7e-42 140.2 16.6 1.2e-12 48.0 0.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY43627.1 - 2.4e-14 53.4 0.8 0.0007 19.8 0.1 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY43627.1 - 5.5e-07 28.9 0.7 0.35 9.8 0.0 4.2 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIY43627.1 - 1.2e-05 24.2 1.5 1.1 7.9 0.1 4.0 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIY43627.1 - 0.00033 19.5 0.7 0.08 11.7 0.1 3.6 1 1 3 4 4 4 1 Nup133 N terminal like Hira PF07569.11 KIY43627.1 - 0.00069 19.4 0.5 2.3 7.9 0.0 3.4 1 1 3 5 5 5 3 TUP1-like enhancer of split DUF3642 PF12182.8 KIY43627.1 - 0.012 15.8 0.0 2.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial lipoprotein Frtz PF11768.8 KIY43627.1 - 0.02 13.2 0.0 0.07 11.4 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIY43627.1 - 0.075 11.6 0.0 2.5 6.5 0.0 2.6 2 1 0 2 2 2 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 KIY43627.1 - 0.11 11.4 1.8 0.15 10.9 0.0 2.1 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Peptidase_M24 PF00557.24 KIY43628.1 - 1.8e-43 148.7 0.1 2.3e-43 148.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KIY43628.1 - 3.8e-05 24.3 0.0 8.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain EF-hand_1 PF00036.32 KIY43629.1 - 3.8e-23 79.3 0.7 3.5e-06 26.2 0.1 4.7 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIY43629.1 - 3.9e-21 75.3 0.0 3.5e-10 40.2 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY43629.1 - 9.8e-21 71.9 0.1 7.9e-06 25.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KIY43629.1 - 1.9e-16 58.7 0.1 0.00031 20.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIY43629.1 - 1.1e-13 50.8 4.3 2.7e-08 33.5 0.2 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KIY43629.1 - 0.00068 19.6 1.4 0.0047 16.9 0.3 2.3 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KIY43629.1 - 0.029 14.3 0.0 0.6 10.0 0.0 2.6 1 1 1 3 3 3 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 KIY43629.1 - 0.054 13.8 0.4 0.4 11.0 0.0 2.3 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AMP-binding PF00501.28 KIY43630.1 - 1.1e-79 268.0 0.0 1.5e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY43630.1 - 1.7e-05 25.7 0.1 3.5e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IGPD PF00475.18 KIY43631.1 - 1.1e-58 197.6 0.2 2.5e-58 196.5 0.1 1.6 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase CCSAP PF15748.5 KIY43632.1 - 5.4 7.1 10.7 9 6.4 10.7 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated HAGH_C PF16123.5 KIY43633.1 - 1.6e-21 76.6 0.0 2.7e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KIY43633.1 - 0.00017 21.6 6.8 0.0052 16.8 6.8 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF695 PF05117.12 KIY43633.1 - 0.06 13.5 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF695) DUF4988 PF16378.5 KIY43633.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Got1 PF04178.12 KIY43634.1 - 1.7e-25 89.7 23.3 1.7e-25 89.7 23.3 1.5 1 1 1 2 2 2 2 Got1/Sft2-like family zinc_ribbon_15 PF17032.5 KIY43636.1 - 1.8e-05 25.4 2.3 2.5e-05 24.9 2.3 1.3 1 0 0 1 1 1 1 zinc-ribbon family DUF3716 PF12511.8 KIY43636.1 - 0.034 14.2 0.7 0.05 13.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) zinc_ribbon_9 PF14369.6 KIY43636.1 - 0.22 11.8 0.9 0.22 11.8 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbon Ras PF00071.22 KIY43637.1 - 4.6e-65 218.1 1.1 5.3e-65 217.9 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY43637.1 - 5.2e-36 123.5 0.1 9e-36 122.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY43637.1 - 9.9e-17 60.9 0.3 1.2e-16 60.7 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIY43637.1 - 5.1e-07 29.7 1.1 0.0065 16.4 0.3 2.4 1 1 1 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 KIY43637.1 - 2.4e-05 23.8 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KIY43637.1 - 2.5e-05 23.8 0.1 3.2e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KIY43637.1 - 3.8e-05 23.3 0.3 0.0001 21.9 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY43637.1 - 6.6e-05 23.0 0.0 0.00016 21.8 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY43637.1 - 0.0024 17.4 0.1 0.016 14.7 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KIY43637.1 - 0.0071 16.7 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIY43637.1 - 0.0077 16.7 0.1 1.2 9.6 0.0 2.5 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIY43637.1 - 0.042 13.4 0.1 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIY43637.1 - 0.049 13.9 0.0 0.092 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIY43637.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KIY43637.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KIY43637.1 - 0.076 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 KIY43637.1 - 0.079 12.7 0.1 1.3 8.8 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KIY43637.1 - 0.083 13.4 0.0 0.12 12.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 KIY43637.1 - 0.09 12.2 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Img2 PF05046.14 KIY43639.1 - 4.7e-16 58.8 0.0 6.1e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DUF2635 PF10948.8 KIY43639.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Zn_clus PF00172.18 KIY43640.1 - 1.9e-07 31.1 6.8 4.5e-07 29.9 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.10 KIY43641.1 - 3.5e-46 157.9 0.0 4.9e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 QCR10 PF09796.9 KIY43642.1 - 4.3e-19 68.3 0.2 4.9e-19 68.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HAD_2 PF13419.6 KIY43643.1 - 2.7e-05 24.3 0.0 4.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY43643.1 - 0.0049 16.9 0.0 0.0084 16.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like SRP-alpha_N PF04086.13 KIY43644.1 - 1.1e-47 163.3 6.6 6.8e-46 157.5 6.6 2.2 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KIY43644.1 - 2.2e-46 158.0 0.1 8e-46 156.1 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KIY43644.1 - 6.3e-08 32.7 0.0 1.7e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KIY43644.1 - 1.8e-05 23.9 0.1 4.1e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KIY43644.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KIY43644.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KIY43644.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 KIY43644.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 KIY43644.1 - 0.045 13.7 0.1 0.24 11.3 0.1 2.2 1 1 0 1 1 1 0 NTPase ArsA_ATPase PF02374.15 KIY43644.1 - 0.047 12.9 1.0 1.8 7.7 0.1 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_31 PF13614.6 KIY43644.1 - 0.07 13.0 0.2 1.5 8.7 0.0 2.2 1 1 0 2 2 2 0 AAA domain GTP_CH_N PF12471.8 KIY43644.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal MMR_HSR1 PF01926.23 KIY43644.1 - 0.15 12.2 0.5 1.1 9.3 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cyclin_N PF00134.23 KIY43645.1 - 4.3e-09 36.2 0.0 9.1e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KIY43645.1 - 0.029 14.8 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain TPR_14 PF13428.6 KIY43646.1 - 8.7e-12 44.8 18.2 0.41 11.6 0.0 11.2 10 2 2 12 12 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY43646.1 - 4.5e-07 29.5 15.6 0.089 13.0 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 KIY43646.1 - 7.4e-06 26.2 6.6 0.0011 19.1 0.4 5.0 3 1 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KIY43646.1 - 1.5e-05 25.4 13.0 0.17 12.4 0.3 5.9 6 1 0 6 6 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KIY43646.1 - 4.3e-05 23.5 10.0 1 9.3 0.6 6.4 7 0 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 KIY43646.1 - 0.00015 21.9 8.2 5.4 7.4 0.4 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KIY43646.1 - 0.0096 15.1 9.3 0.47 9.5 0.1 4.8 3 2 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 KIY43646.1 - 0.013 15.4 5.7 5.6 7.2 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY43646.1 - 0.016 15.4 8.9 43 4.7 0.3 7.7 8 1 0 8 8 8 0 Tetratricopeptide repeat HAT PF02184.16 KIY43646.1 - 0.031 14.2 9.1 2.4 8.2 0.1 6.0 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat MIT PF04212.18 KIY43646.1 - 0.13 12.4 1.1 1 9.5 0.1 3.2 3 1 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KIY43646.1 - 0.17 11.7 5.8 8.7 6.4 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY43646.1 - 0.2 12.3 7.7 46 4.8 0.2 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIY43646.1 - 1.1 9.8 8.3 14 6.3 0.1 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY43646.1 - 2.1 9.1 11.1 64 4.5 0.0 6.4 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY43646.1 - 2.2 9.1 8.5 0.57 11.0 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 KIY43647.1 - 6.6e-37 127.2 22.8 6.6e-37 127.2 22.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY43647.1 - 1.2e-07 31.4 5.0 1.2e-07 31.4 5.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB EphA2_TM PF14575.6 KIY43647.1 - 0.11 13.4 0.4 14 6.6 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2929 PF11151.8 KIY43647.1 - 2.5 8.4 12.3 0.23 11.8 0.5 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2929) NAD_binding_4 PF07993.12 KIY43648.1 - 1.3e-36 126.1 0.0 2.3e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIY43648.1 - 6.4e-29 100.8 0.0 1.9e-28 99.2 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIY43648.1 - 2.7e-12 46.7 0.0 7.9e-12 45.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY43648.1 - 2e-06 28.0 0.0 4.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 KIY43648.1 - 0.0049 16.0 0.2 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KIY43648.1 - 0.0057 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIY43648.1 - 0.024 14.5 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KIY43648.1 - 0.069 13.6 0.1 0.25 11.8 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain BRO1 PF03097.18 KIY43649.1 - 3.5e-95 319.1 0.0 6.7e-95 318.1 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KIY43649.1 - 8e-66 222.3 18.3 1.2e-65 221.8 18.3 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV N_formyltrans_C PF18216.1 KIY43649.1 - 0.11 12.1 0.0 0.41 10.4 0.0 2.0 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain TPR_1 PF00515.28 KIY43649.1 - 0.12 12.2 2.9 1.3 9.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.18 KIY43651.1 - 2.5e-06 27.5 7.0 4.4e-06 26.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Luteo_PO PF04662.13 KIY43651.1 - 0.0093 15.7 0.2 0.83 9.3 0.0 2.2 2 0 0 2 2 2 2 Luteovirus P0 protein CK2S PF15011.6 KIY43652.1 - 0.00085 19.2 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 Casein Kinase 2 substrate Syntaxin-6_N PF09177.11 KIY43652.1 - 0.084 13.4 1.5 0.25 11.9 0.1 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HLH PF00010.26 KIY43652.1 - 0.094 12.7 0.4 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Corona_S2 PF01601.16 KIY43652.1 - 0.15 10.5 0.2 0.19 10.2 0.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Peptidase_C78 PF07910.13 KIY43653.1 - 8.2e-28 97.3 0.0 3.5e-27 95.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C78 MAT1 PF06391.13 KIY43654.1 - 6.1e-56 189.5 16.7 7.5e-56 189.2 16.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KIY43654.1 - 2.6e-22 78.5 5.9 4.3e-22 77.8 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY43654.1 - 0.0031 17.8 5.1 0.0052 17.1 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY43654.1 - 0.0059 16.4 5.6 0.016 15.0 5.7 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3797 PF12677.7 KIY43654.1 - 0.032 14.1 1.1 0.032 14.1 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-RING_5 PF14634.6 KIY43654.1 - 0.054 13.5 3.7 0.76 9.8 0.5 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIY43654.1 - 0.066 13.1 7.6 0.18 11.6 7.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY43654.1 - 0.068 13.0 6.2 0.25 11.2 6.4 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA_23 PF13476.6 KIY43654.1 - 0.46 11.0 8.3 0.67 10.4 8.3 1.2 1 0 0 1 1 1 0 AAA domain Prok-RING_4 PF14447.6 KIY43654.1 - 0.93 9.4 5.0 5 7.1 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 LigB PF02900.18 KIY43655.1 - 3.1e-39 134.7 0.0 3.7e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Gcn1_N PF12074.8 KIY43656.1 - 8.2e-66 222.7 3.8 1.3e-65 222.1 0.2 3.3 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KIY43656.1 - 1e-44 146.7 18.4 0.027 14.7 0.0 24.8 27 0 0 27 27 25 9 HEAT repeat HEAT_EZ PF13513.6 KIY43656.1 - 2.7e-38 129.9 26.7 0.00035 21.0 0.1 19.1 17 4 5 22 22 20 8 HEAT-like repeat HEAT_2 PF13646.6 KIY43656.1 - 1.6e-31 108.6 44.1 9.4e-05 22.7 0.0 17.7 14 4 7 21 21 21 9 HEAT repeats Cnd1 PF12717.7 KIY43656.1 - 8.3e-17 61.7 0.0 0.049 13.7 0.1 9.8 6 4 4 10 10 10 4 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIY43656.1 - 8.5e-14 51.0 1.4 0.12 10.9 0.0 8.6 6 3 3 9 9 9 3 Adaptin N terminal region CLASP_N PF12348.8 KIY43656.1 - 2.8e-13 49.9 0.1 0.00024 20.7 0.0 7.6 5 1 0 7 7 7 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 KIY43656.1 - 9e-08 32.6 0.0 58 4.4 0.0 8.6 7 2 1 9 9 8 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KIY43656.1 - 7.1e-07 28.6 10.0 0.26 10.3 0.0 8.2 8 2 1 9 9 9 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 KIY43656.1 - 3.3e-06 27.2 0.9 12 6.2 0.0 7.9 9 1 0 9 9 8 0 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 KIY43656.1 - 9.1e-06 25.5 1.9 0.69 9.9 0.1 8.1 8 1 1 9 9 9 1 UME (NUC010) domain Arm PF00514.23 KIY43656.1 - 2e-05 24.4 0.2 11 6.2 0.0 7.1 7 0 0 7 7 5 0 Armadillo/beta-catenin-like repeat DUF4042 PF13251.6 KIY43656.1 - 5.8e-05 22.9 1.2 1.6 8.4 0.0 6.3 6 1 0 6 6 6 1 Domain of unknown function (DUF4042) RIX1 PF08167.12 KIY43656.1 - 0.00013 21.8 13.1 2.7 7.7 0.1 7.5 7 1 1 8 8 8 3 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 KIY43656.1 - 0.00036 20.5 0.2 5.5 6.9 0.0 6.7 5 2 1 6 6 6 1 Domain of unknown function (DUF3385) DUF3437 PF11919.8 KIY43656.1 - 0.0044 16.9 1.4 1.6 8.7 0.0 5.3 6 0 0 6 6 5 1 Domain of unknown function (DUF3437) HEAT_PBS PF03130.16 KIY43656.1 - 0.082 13.6 9.4 59 4.8 0.2 7.5 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat Telomere_reg-2 PF10193.9 KIY43656.1 - 0.12 12.8 3.3 2.7 8.5 0.2 4.5 4 0 0 4 4 3 0 Telomere length regulation protein ParcG PF10274.9 KIY43656.1 - 0.13 12.3 5.7 63 3.6 0.0 6.6 7 2 2 9 9 8 0 Parkin co-regulated protein MMS19_N PF14500.6 KIY43656.1 - 0.48 10.0 9.3 4.8 6.7 0.0 5.9 8 0 0 8 8 8 0 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KIY43656.1 - 0.7 8.9 18.3 3.4 6.7 0.0 7.6 8 3 1 9 9 9 0 RNAPII transcription regulator C-terminal DUF2267 PF10025.9 KIY43656.1 - 1.6 9.0 5.1 4.1 7.7 0.2 3.8 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2267) Borrelia_P83 PF05262.11 KIY43657.1 - 0.022 13.3 11.7 0.027 13.0 11.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF572 PF04502.13 KIY43657.1 - 0.15 11.7 23.3 0.29 10.7 23.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) NMO PF03060.15 KIY43658.1 - 5.5e-44 150.9 1.0 8.2e-44 150.3 1.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIY43658.1 - 1.6e-06 27.3 0.0 8.9e-06 24.9 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIY43658.1 - 0.0067 15.5 4.7 0.01 14.9 4.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF3445 PF11927.8 KIY43659.1 - 7.2e-74 248.2 0.1 9e-74 247.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MoCF_biosynth PF00994.24 KIY43659.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Probable molybdopterin binding domain WD40 PF00400.32 KIY43660.1 - 5.9e-16 58.6 11.0 7.3e-08 33.0 0.0 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat tRNA-synt_1c PF00749.21 KIY43661.1 - 3.8e-100 334.8 0.0 2.2e-99 332.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KIY43661.1 - 2.6e-31 108.8 0.1 4.1e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 KIY43661.1 - 0.013 15.5 0.1 0.037 14.1 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY43661.1 - 0.028 14.6 0.0 0.093 13.0 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Adeno_E1B_55K_N PF04623.12 KIY43661.1 - 0.037 14.7 1.0 0.27 11.9 0.6 2.5 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus tRNA-synt_1e PF01406.19 KIY43661.1 - 0.093 12.1 0.0 0.23 10.8 0.0 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Git3 PF11710.8 KIY43662.1 - 0.014 15.2 0.7 0.022 14.5 0.7 1.3 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 SPT16 PF08644.11 KIY43663.1 - 9.4e-54 181.7 0.3 2.6e-53 180.3 0.1 1.9 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KIY43663.1 - 5.8e-39 133.5 0.0 2.8e-38 131.2 0.0 2.2 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KIY43663.1 - 6.1e-26 91.4 0.0 1.1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KIY43663.1 - 2e-13 50.6 0.0 6.1e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 KIY43663.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) SnAC PF14619.6 KIY43663.1 - 1.4 9.5 5.9 12 6.6 3.3 3.2 2 1 1 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex XhlA PF10779.9 KIY43663.1 - 4.6 7.5 6.6 10 6.4 2.4 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Bcl-2_3 PF15286.6 KIY43664.1 - 0.049 14.3 0.0 0.23 12.1 0.0 1.9 2 0 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like MFS_1 PF07690.16 KIY43665.1 - 5.5e-14 51.9 42.9 9.9e-11 41.1 21.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UL41A PF17591.2 KIY43665.1 - 2.1 8.5 4.9 1.5 8.9 0.2 3.0 3 0 0 3 3 3 0 Herpesvirus UL41A DUF3290 PF11694.8 KIY43665.1 - 2.9 7.9 6.1 0.34 10.9 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3290) PPTA PF01239.22 KIY43667.1 - 7.4e-41 136.7 17.7 1.6e-10 40.3 0.8 5.8 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Parathyroid PF01279.17 KIY43667.1 - 0.079 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Parathyroid hormone family DEAD PF00270.29 KIY43668.1 - 4.3e-21 75.5 0.1 7.7e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY43668.1 - 5.9e-16 58.8 0.1 7.4e-13 48.8 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DUF1998 PF09369.10 KIY43668.1 - 7.2e-12 45.9 0.5 3e-11 43.9 0.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.15 KIY43668.1 - 6.1e-06 26.4 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KIY43668.1 - 0.0002 21.7 0.0 0.00037 20.8 0.0 1.3 1 0 0 1 1 1 1 DNA replication factor CDT1 like Pkinase PF00069.25 KIY43669.1 - 8.8e-21 74.4 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43669.1 - 2.5e-12 46.6 0.0 6.2e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Phage_coat PF09063.10 KIY43669.1 - 0.24 11.4 0.4 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Phage PP7 coat protein LRR_6 PF13516.6 KIY43670.1 - 8.9e-06 25.4 10.5 3.4 7.9 0.0 6.8 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 KIY43670.1 - 0.0029 18.0 14.8 21 5.7 0.0 5.7 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) DUF4640 PF15480.6 KIY43670.1 - 0.0081 16.0 0.3 0.012 15.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4640) LRR_1 PF00560.33 KIY43670.1 - 0.34 11.6 8.9 6.2 7.8 0.1 4.9 4 2 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KIY43670.1 - 1.6 8.5 0.0 1.6 8.5 0.0 5.0 5 2 0 5 5 5 0 Leucine rich repeat His_Phos_2 PF00328.22 KIY43671.1 - 4.5e-35 121.7 0.0 6.4e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Epimerase PF01370.21 KIY43672.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KIY43673.1 - 3.3e-34 118.4 0.1 6e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KIY43673.1 - 1.7e-28 99.3 0.0 2.9e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ADD_ATRX PF17981.1 KIY43673.1 - 0.096 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Cysteine Rich ADD domain Phage_integrase PF00589.22 KIY43675.1 - 0.00033 20.5 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF3684 PF12449.8 KIY43675.1 - 0.017 12.9 0.1 0.022 12.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Fungal_trans PF04082.18 KIY43676.1 - 9e-16 57.7 0.1 1.5e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY43676.1 - 0.00046 20.2 14.0 0.00094 19.3 14.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KIY43677.1 - 5.8e-66 222.6 0.0 9.9e-66 221.8 0.0 1.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43677.1 - 7.2e-30 104.1 0.0 9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY43677.1 - 9.3e-05 21.9 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Proteasome PF00227.26 KIY43678.1 - 4.3e-61 205.7 0.1 6.7e-61 205.1 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY43678.1 - 2e-14 53.0 0.4 1.1e-13 50.5 0.1 2.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Cytochrom_B561 PF03188.16 KIY43679.1 - 2.4e-09 37.4 8.7 4.7e-09 36.5 8.6 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KIY43679.1 - 1.3 9.2 8.7 0.3 11.3 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Promethin PF16015.5 KIY43679.1 - 3.8 7.5 14.2 0.081 12.9 6.1 2.2 2 1 0 2 2 2 0 Promethin Sec7 PF01369.20 KIY43680.1 - 1.3e-64 217.3 0.2 2.1e-64 216.6 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KIY43680.1 - 2.1e-18 66.7 0.8 2.1e-16 60.2 0.0 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KIY43680.1 - 0.00082 19.2 0.6 0.8 9.6 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Phage_Coat_Gp8 PF05371.12 KIY43680.1 - 0.092 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Phage major coat protein, Gp8 5_nucleotid_C PF02872.18 KIY43682.1 - 5.8e-26 91.6 0.0 1.1e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KIY43682.1 - 7.6e-09 36.4 0.4 7.6e-09 36.4 0.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TamB PF04357.13 KIY43682.1 - 0.039 13.2 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex Transposon_TraM PF12508.8 KIY43682.1 - 0.13 12.0 0.8 0.39 10.4 0.2 1.9 2 0 0 2 2 2 0 Conjugative transposon, TraM ING PF12998.7 KIY43683.1 - 3.7e-08 33.9 0.1 0.0027 18.3 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIY43683.1 - 4.7e-05 23.2 6.3 7.9e-05 22.5 6.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIY43683.1 - 0.0014 18.1 1.5 0.0024 17.4 1.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KIY43683.1 - 0.17 12.2 3.0 0.35 11.1 3.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Acetyltransf_8 PF13523.6 KIY43684.1 - 7.3e-27 93.8 0.2 1.1e-26 93.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2235 PF09994.9 KIY43685.1 - 5.8e-85 285.1 0.0 7.3e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Condensation PF00668.20 KIY43686.1 - 5.8e-76 256.0 0.0 4.3e-31 108.1 0.0 5.7 5 2 0 5 5 5 4 Condensation domain AMP-binding PF00501.28 KIY43686.1 - 1.6e-67 227.9 0.0 5.8e-66 222.8 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KIY43686.1 - 1.1e-25 89.7 7.7 2.3e-08 34.3 0.7 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site Pkinase_fungal PF17667.1 KIY43687.1 - 3.5e-25 88.6 0.0 3.8e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase EF-hand_4 PF12763.7 KIY43688.1 - 1.7e-31 108.2 0.0 5.8e-13 48.7 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KIY43688.1 - 2.5e-08 34.3 0.1 5.1e-05 23.6 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair UBA PF00627.31 KIY43688.1 - 6e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Fez1 PF06818.15 KIY43688.1 - 0.0053 17.2 15.2 0.0053 17.2 15.2 2.3 1 1 1 2 2 2 1 Fez1 DUF3584 PF12128.8 KIY43688.1 - 0.032 11.8 21.9 0.057 10.9 21.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EF-hand_6 PF13405.6 KIY43688.1 - 1.9 8.6 7.5 14 6.0 0.0 4.5 5 0 0 5 5 4 0 EF-hand domain DUF1664 PF07889.12 KIY43688.1 - 2 8.5 14.0 2.8 8.0 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 KIY43688.1 - 3.3 5.5 7.2 5 4.9 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KIY43688.1 - 3.6 6.4 31.3 1.4 7.7 9.6 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 KIY43688.1 - 5.4 6.5 25.2 3 7.3 16.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein Bacillus_HBL PF05791.11 KIY43688.1 - 5.6 6.7 12.0 0.37 10.6 4.0 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Endonuclease_NS PF01223.23 KIY43689.1 - 3.9e-55 187.1 0.0 4.5e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Cyt-b5 PF00173.28 KIY43690.1 - 2.2e-12 47.0 0.0 2.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF974 PF06159.13 KIY43691.1 - 1e-75 254.7 0.0 1.3e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) MRP-L46 PF11788.8 KIY43692.1 - 7.7e-19 68.6 0.1 1.3e-18 67.9 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KIY43692.1 - 7.1e-07 29.3 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain V-ATPase_H_N PF03224.14 KIY43693.1 - 3.8e-86 289.2 0.4 3.8e-86 289.2 0.4 1.4 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KIY43693.1 - 7.6e-41 138.9 0.2 7.6e-41 138.9 0.2 2.6 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 KIY43693.1 - 0.0011 19.0 1.3 0.41 10.8 0.0 4.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 KIY43693.1 - 0.0097 15.4 0.3 0.033 13.7 0.1 1.9 2 0 0 2 2 2 1 Armadillo-like HEAT PF02985.22 KIY43693.1 - 0.1 12.9 0.0 9 6.9 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat zf-C2H2 PF00096.26 KIY43694.1 - 0.00015 22.1 13.1 0.003 17.9 0.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 KIY43694.1 - 0.0083 16.5 0.1 0.68 10.4 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIY43694.1 - 0.014 16.2 1.9 0.11 13.3 0.3 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY43694.1 - 0.098 13.0 0.2 0.098 13.0 0.2 2.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RNA12 PF10443.9 KIY43695.1 - 8e-103 344.5 0.0 2.2e-55 188.2 0.0 2.1 1 1 1 2 2 2 2 RNA12 protein RRM_1 PF00076.22 KIY43695.1 - 5.9e-06 26.0 0.0 2.1e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KIY43695.1 - 8.4e-06 26.3 0.0 5.7e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KIY43695.1 - 0.0017 18.3 0.0 0.0039 17.1 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIY43695.1 - 0.0058 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY43695.1 - 0.076 13.2 0.1 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MBF1 PF08523.10 KIY43696.1 - 3.7e-26 91.4 1.5 7.3e-26 90.4 1.5 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KIY43696.1 - 7.2e-12 45.2 0.1 1.2e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIY43696.1 - 6.8e-06 26.3 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KIY43696.1 - 0.022 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Tubulin PF00091.25 KIY43697.1 - 1.4e-70 237.6 0.0 4e-70 236.0 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY43697.1 - 2.3e-47 160.3 0.6 4e-47 159.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIY43697.1 - 0.00068 19.9 0.0 0.0032 17.8 0.0 2.1 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KIY43697.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Hrs_helical PF12210.8 KIY43697.1 - 0.0072 16.8 0.1 0.019 15.5 0.1 1.6 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Tubulin_2 PF13809.6 KIY43697.1 - 0.056 12.6 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Peptidase_S9 PF00326.21 KIY43698.1 - 4.5e-07 29.5 0.1 7.8e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIY43698.1 - 8.4e-07 28.9 0.3 1.8e-06 27.8 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY43698.1 - 3.3e-05 23.3 0.1 0.00047 19.5 0.0 2.1 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KIY43698.1 - 0.00023 20.9 0.7 0.00044 20.0 0.7 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KIY43698.1 - 0.00059 19.7 0.0 0.35 10.7 0.0 2.8 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Tannase PF07519.11 KIY43698.1 - 0.03 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase DLH PF01738.18 KIY43698.1 - 0.047 13.2 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.8 KIY43698.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MCM_bind PF09739.9 KIY43699.1 - 4.1e-68 230.3 0.0 1.7e-56 191.9 0.0 3.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor PHD PF00628.29 KIY43700.1 - 9.1e-17 60.7 17.2 1.3e-10 41.0 5.8 2.6 3 0 0 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.6 KIY43700.1 - 0.00077 19.7 6.6 0.0017 18.6 2.1 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KIY43700.1 - 0.0034 16.9 7.8 0.11 12.1 0.5 2.9 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KIY43700.1 - 0.0054 16.4 2.3 0.031 13.9 0.5 2.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain zf-HC5HC2H_2 PF13832.6 KIY43700.1 - 0.016 15.3 1.6 0.041 14.0 0.2 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain AT_hook PF02178.19 KIY43700.1 - 0.33 11.0 8.5 1.2 9.3 8.5 2.0 1 0 0 1 1 1 0 AT hook motif PHD_4 PF16866.5 KIY43700.1 - 0.97 9.6 14.9 0.52 10.4 1.6 2.6 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KIY43700.1 - 1.1 9.2 10.3 2 8.3 1.6 2.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_C48 PF02902.19 KIY43701.1 - 2.2e-05 24.4 0.1 7.1e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PGM_PMM_I PF02878.16 KIY43702.1 - 1.5e-37 128.4 0.0 2.8e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KIY43702.1 - 2.7e-19 69.7 0.0 5.3e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KIY43702.1 - 5.4e-18 65.3 0.3 3e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KIY43702.1 - 2.5e-05 24.3 0.0 6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CDC50 PF03381.15 KIY43703.1 - 8.7e-92 307.6 0.0 1.1e-91 307.2 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Striatin PF08232.12 KIY43704.1 - 2.8e-51 174.2 7.7 1.7e-49 168.3 0.0 2.5 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KIY43704.1 - 4.7e-35 119.0 8.7 5.6e-06 27.0 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY43704.1 - 4.2e-07 30.2 0.1 3.6 8.0 0.0 5.2 3 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KIY43704.1 - 0.0011 17.8 0.0 0.13 11.0 0.0 3.2 2 2 1 3 3 3 1 Nup133 N terminal like TFIIA PF03153.13 KIY43704.1 - 0.0036 17.4 20.3 0.004 17.2 11.0 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Nup160 PF11715.8 KIY43704.1 - 0.047 12.3 0.1 0.57 8.8 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 GET2 PF08690.10 KIY43704.1 - 2.4 7.7 7.0 6.4 6.3 7.0 1.7 1 0 0 1 1 1 0 GET complex subunit GET2 TMA7 PF09072.10 KIY43705.1 - 1.1e-21 77.4 23.6 1.2e-21 77.2 23.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 RNA_pol_Rpc82 PF05645.13 KIY43706.1 - 5.7e-21 75.4 1.7 1.5e-16 61.0 1.8 3.3 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KIY43706.1 - 6e-21 74.3 0.9 1.4e-16 60.3 0.3 3.7 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KIY43706.1 - 4.9e-12 45.6 0.0 5e-06 26.3 0.1 3.8 3 0 0 3 3 3 2 TFIIE alpha subunit DprA_WH PF17782.1 KIY43706.1 - 0.0065 16.6 0.3 0.036 14.2 0.3 2.3 2 0 0 2 2 2 1 DprA winged helix domain R3H PF01424.22 KIY43707.1 - 3.6e-12 46.1 0.1 7.1e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KIY43707.1 - 4.7e-08 32.7 0.0 1.4e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 KIY43709.1 - 6.3e-44 149.0 0.0 7.7e-44 148.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY43709.1 - 0.00055 19.6 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KIY43709.1 - 0.00056 20.2 0.0 0.00062 20.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain CLASP_N PF12348.8 KIY43710.1 - 1e-16 61.2 0.0 1.3e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal LMSTEN PF07988.12 KIY43710.1 - 0.011 15.2 0.2 0.027 14.0 0.1 1.7 2 0 0 2 2 2 0 LMSTEN motif HEAT PF02985.22 KIY43710.1 - 0.013 15.7 0.0 0.52 10.7 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Not1 PF04054.15 KIY43711.1 - 1.4e-114 382.9 0.1 2.7e-114 381.9 0.1 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KIY43711.1 - 2.6e-66 223.2 0.0 1.7e-65 220.6 0.0 2.5 2 1 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 KIY43711.1 - 1.9e-50 170.7 0.0 3.6e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 KIY43711.1 - 1.2e-49 168.0 0.0 2.7e-49 166.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 KIY43711.1 - 1.2e-41 142.3 0.0 3.1e-41 140.9 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Alpha-amylase PF00128.24 KIY43712.1 - 4.2e-48 164.6 0.2 7.1e-48 163.9 0.2 1.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIY43712.1 - 2.3e-11 43.8 0.0 4.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Arylsulfotran_2 PF14269.6 KIY43713.1 - 2.1e-28 99.6 0.0 6.6e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY43713.1 - 2.4e-07 30.0 0.0 0.047 12.6 0.0 3.1 2 1 0 2 2 2 2 Arylsulfotransferase (ASST) PDEase_II PF02112.15 KIY43715.1 - 1.6e-50 172.1 0.0 5.1e-50 170.5 0.0 1.7 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KIY43715.1 - 0.0073 15.8 0.1 0.018 14.5 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HOOK PF05622.12 KIY43716.1 - 5.2e-60 203.4 67.8 1.8e-57 195.0 39.2 2.3 1 1 1 2 2 2 2 HOOK protein HMMR_N PF15905.5 KIY43716.1 - 0.0026 17.3 21.7 0.0026 17.3 21.7 5.2 1 1 2 5 5 5 1 Hyaluronan mediated motility receptor N-terminal bZIP_1 PF00170.21 KIY43716.1 - 0.011 15.8 1.9 0.011 15.8 1.9 8.6 8 1 2 10 10 10 0 bZIP transcription factor NYD-SP28_assoc PF14775.6 KIY43716.1 - 0.016 15.3 1.5 0.016 15.3 1.5 7.0 6 1 1 7 7 7 0 Sperm tail C-terminal domain DUF2553 PF10830.8 KIY43716.1 - 0.16 12.8 2.5 0.46 11.3 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2553) Pox_A_type_inc PF04508.12 KIY43716.1 - 0.52 10.2 6.7 7.7 6.5 0.0 5.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat T4bSS_IcmS PF12608.8 KIY43716.1 - 1.6 9.1 6.2 10 6.5 1.1 3.5 2 1 1 3 3 3 0 Type IVb secretion, IcmS, effector-recruitment AMP-binding PF00501.28 KIY43717.1 - 3.6e-25 88.5 0.7 4.3e-24 84.9 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIY43717.1 - 1.4e-12 47.3 0.0 3e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.21 KIY43717.1 - 2.6e-06 27.1 0.0 2e-05 24.2 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIY43717.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MT-A70 PF05063.14 KIY43718.1 - 4.7e-40 137.3 0.0 1e-39 136.2 0.0 1.5 1 1 0 1 1 1 1 MT-A70 DEAD PF00270.29 KIY43721.1 - 9e-21 74.4 0.0 1e-19 71.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY43721.1 - 1.7e-19 70.2 0.0 5e-18 65.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.10 KIY43721.1 - 2.7e-15 56.2 0.1 8.2e-15 54.6 0.0 1.9 2 0 0 2 2 2 1 RQC domain RecQ_Zn_bind PF16124.5 KIY43721.1 - 7.1e-14 52.3 2.5 2.1e-13 50.8 2.5 1.9 1 0 0 1 1 1 1 RecQ zinc-binding RcpB PF16971.5 KIY43721.1 - 0.0094 15.9 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 1 Rough colony protein B, tight adherence - tad - subunit Amj PF10997.8 KIY43721.1 - 0.039 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Alternate to MurJ ResIII PF04851.15 KIY43721.1 - 0.08 12.9 0.0 0.33 10.9 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase PF00069.25 KIY43722.1 - 4.6e-54 183.5 0.0 6.1e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43722.1 - 8.4e-19 67.9 0.6 1.3e-18 67.3 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KIY43722.1 - 0.0042 17.0 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY43722.1 - 0.0094 15.6 0.5 0.02 14.5 0.5 1.6 1 0 0 1 1 1 1 RIO1 family ABC1 PF03109.16 KIY43722.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC1 family FA_desaturase PF00487.24 KIY43723.1 - 2.9e-32 112.5 30.9 2.9e-32 112.5 30.9 1.8 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 KIY43723.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Ycf4 PF02392.16 KIY43723.1 - 0.096 12.3 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Ycf4 DUF1673 PF07895.11 KIY43723.1 - 1.3 8.7 5.8 0.93 9.2 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) BCDHK_Adom3 PF10436.9 KIY43724.1 - 5e-27 94.7 0.0 7.2e-16 58.4 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIY43724.1 - 1.2e-08 35.4 0.0 6.6e-06 26.6 0.0 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIY43724.1 - 0.024 14.5 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ETC_C1_NDUFA5 PF04716.14 KIY43725.1 - 2e-23 81.9 0.0 3.7e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ribosomal_L32p PF01783.23 KIY43726.1 - 2.4e-17 62.9 4.3 3e-17 62.6 4.3 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 KIY43726.1 - 0.088 12.8 3.2 0.14 12.1 3.1 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 LSM PF01423.22 KIY43727.1 - 1e-17 63.6 0.7 1.3e-17 63.3 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY43727.1 - 0.009 16.1 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain ATP-synt_ab PF00006.25 KIY43728.1 - 1e-107 358.6 0.0 1.4e-107 358.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KIY43728.1 - 8.4e-44 148.3 0.0 1.5e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KIY43728.1 - 4.8e-15 55.8 3.4 1.3e-14 54.4 3.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SLX9 PF15341.6 KIY43730.1 - 1 9.8 8.6 1 9.7 7.5 1.6 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 CPL PF08144.11 KIY43736.1 - 0.069 13.5 0.0 0.078 13.3 0.0 1.1 1 0 0 1 1 1 0 CPL (NUC119) domain AA_permease PF00324.21 KIY43737.1 - 1.2e-14 53.8 4.3 1.5e-14 53.5 4.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY43737.1 - 5.1e-05 22.3 1.6 6.3e-05 22.0 1.6 1.1 1 0 0 1 1 1 1 Amino acid permease 2OG-FeII_Oxy_3 PF13640.6 KIY43741.1 - 0.042 14.7 0.0 0.064 14.2 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily KDZ PF18758.1 KIY43744.1 - 1.4e-24 86.9 0.6 1.7e-24 86.7 0.6 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Macoilin PF09726.9 KIY43747.1 - 0.99 7.9 4.4 1.1 7.7 4.4 1.0 1 0 0 1 1 1 0 Macoilin family Retrotran_gag_2 PF14223.6 KIY43750.1 - 1.1e-08 34.9 0.5 0.00095 18.8 0.1 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIY43750.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) SPX PF03105.19 KIY43751.1 - 7 6.5 9.2 10 5.9 9.2 1.1 1 0 0 1 1 1 0 SPX domain FXMRP1_C_core PF12235.8 KIY43752.1 - 0.077 13.6 9.1 0.12 13.0 9.1 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Zn_Tnp_IS1595 PF12760.7 KIY43753.1 - 0.39 10.7 2.5 0.44 10.6 1.0 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HisKA PF00512.25 KIY43755.1 - 2.9e-14 52.8 0.0 8.3e-14 51.4 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 KIY43755.1 - 1.4e-12 48.1 0.1 6.4e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 KIY43755.1 - 3.2e-09 37.5 0.0 0.00011 22.8 0.0 2.9 2 0 0 2 2 2 2 GAF domain Response_reg PF00072.24 KIY43755.1 - 0.012 15.7 0.0 0.52 10.5 0.0 2.4 2 0 0 2 2 2 0 Response regulator receiver domain UDG PF03167.19 KIY43757.1 - 9.2e-20 71.2 0.0 1.5e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily bZIP_1 PF00170.21 KIY43758.1 - 0.00011 22.2 7.2 0.00018 21.5 7.2 1.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY43758.1 - 0.00029 20.8 2.2 0.00029 20.8 2.2 1.5 2 0 0 2 2 2 1 Basic region leucine zipper HAP1_N PF04849.13 KIY43758.1 - 0.0092 15.2 0.4 0.011 15.0 0.4 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Nnf1 PF03980.14 KIY43758.1 - 0.021 15.2 1.0 0.032 14.6 1.0 1.2 1 0 0 1 1 1 0 Nnf1 TSC22 PF01166.18 KIY43758.1 - 0.035 14.4 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family BMFP PF04380.13 KIY43758.1 - 0.042 14.3 2.8 0.071 13.6 2.8 1.3 1 0 0 1 1 1 0 Membrane fusogenic activity ABC_tran_CTD PF16326.5 KIY43758.1 - 0.073 13.3 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain WD40_alt PF14077.6 KIY43758.1 - 0.16 11.8 0.1 0.26 11.2 0.1 1.2 1 0 0 1 1 1 0 Alternative WD40 repeat motif PTPlike_phytase PF14566.6 KIY43759.1 - 3e-114 378.3 0.0 4e-48 163.5 0.0 4.8 4 1 0 4 4 4 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 KIY43759.1 - 0.0039 16.8 0.0 7.7 6.0 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 KIY43759.1 - 0.0052 16.6 0.0 2 8.2 0.0 3.0 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Nucleoporin_FG PF13634.6 KIY43760.1 - 1.8e-27 96.0 145.4 1.3e-11 45.2 34.2 4.8 1 1 3 4 4 4 4 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 KIY43760.1 - 6.3e-06 25.0 43.3 1.1e-05 24.2 43.3 1.4 1 1 0 1 1 1 1 Nucleoporin FG repeated region DUF16 PF01519.16 KIY43760.1 - 0.045 14.2 0.9 0.045 14.2 0.9 2.2 3 0 0 3 3 3 0 Protein of unknown function DUF16 Amidohydro_1 PF01979.20 KIY43762.1 - 1.5e-22 80.4 0.0 1e-21 77.6 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIY43762.1 - 4.1e-12 46.3 0.1 7e-07 29.1 0.1 3.1 3 0 0 3 3 3 2 Amidohydrolase family SLC35F PF06027.12 KIY43763.1 - 9e-99 330.8 15.0 1.1e-98 330.5 15.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KIY43763.1 - 2.1e-06 26.9 0.3 3.9e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KIY43763.1 - 0.29 11.3 23.9 0.27 11.4 0.6 3.2 2 1 1 3 3 3 0 EamA-like transporter family NAP PF00956.18 KIY43764.1 - 2.5e-25 89.2 2.0 3.1e-25 88.9 2.0 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) GOLD_2 PF13897.6 KIY43764.1 - 0.0011 19.5 1.0 0.0023 18.5 1.0 1.5 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking Cwf_Cwc_15 PF04889.12 KIY43764.1 - 0.045 13.5 3.8 0.06 13.1 3.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Senescence PF06911.12 KIY43765.1 - 0.059 13.7 0.0 0.064 13.6 0.0 1.1 1 0 0 1 1 1 0 Senescence-associated protein DHC_N2 PF08393.13 KIY43765.1 - 0.086 11.9 0.7 0.11 11.6 0.7 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Stathmin PF00836.19 KIY43765.1 - 3.7 7.5 11.8 5.4 7.0 11.8 1.2 1 0 0 1 1 1 0 Stathmin family TPR_MLP1_2 PF07926.12 KIY43765.1 - 4.7 7.3 14.9 28 4.8 14.9 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CEND1 PF15677.5 KIY43766.1 - 0.072 13.6 11.2 0.13 12.8 11.2 1.4 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Ndc1_Nup PF09531.10 KIY43766.1 - 1.9 7.1 4.2 2.1 7.0 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KIY43766.1 - 4.1 6.1 7.9 4.9 5.8 7.9 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 KIY43766.1 - 5.6 5.1 11.0 5.9 5.0 11.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NPR3 PF03666.13 KIY43766.1 - 6.2 5.5 8.4 8.7 5.0 8.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GSHPx PF00255.19 KIY43767.1 - 0.078 12.6 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 Glutathione peroxidase Cyclin_N PF00134.23 KIY43768.1 - 3.1e-12 46.3 0.0 3.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY43768.1 - 6.3e-07 29.9 0.2 7.1e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Cyclin Nop52 PF05997.12 KIY43769.1 - 2.2e-73 246.6 0.0 3e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 KIY43769.1 - 1.5e-05 24.7 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II TAN PF11640.8 KIY43769.1 - 0.0094 16.1 0.1 0.81 9.8 0.0 2.9 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair HEAT_2 PF13646.6 KIY43769.1 - 0.074 13.5 0.1 1.8 9.0 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats RNA_pol_Rpb5_C PF01191.19 KIY43770.1 - 4.6e-31 106.5 0.2 9.1e-31 105.5 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KIY43770.1 - 1.8e-29 102.1 0.1 2.7e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KIY43770.1 - 4.9e-05 23.3 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease WD40 PF00400.32 KIY43772.1 - 5.6e-19 68.1 0.3 6.4e-05 23.6 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY43772.1 - 1.3e-05 25.4 0.0 0.027 14.7 0.0 3.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain FA_desaturase PF00487.24 KIY43773.1 - 1.5e-25 90.5 19.1 1.5e-25 90.5 19.1 1.5 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 KIY43773.1 - 0.00012 22.3 0.1 0.00033 20.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) CIA30 PF08547.12 KIY43774.1 - 6.2e-27 94.6 0.1 7.3e-27 94.3 0.1 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 KIY43774.1 - 0.085 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain Cyclin_N PF00134.23 KIY43775.1 - 1e-41 141.6 0.7 1.9e-41 140.8 0.7 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY43775.1 - 4.5e-22 78.4 0.0 8.1e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain DHHC PF01529.20 KIY43777.1 - 3.8e-33 114.4 11.2 3.8e-33 114.4 11.2 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.7 KIY43777.1 - 0.61 10.2 6.9 1.1 9.4 6.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon Ras PF00071.22 KIY43778.1 - 8.4e-57 191.3 0.2 1e-56 191.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY43778.1 - 2.6e-19 69.6 0.0 4.3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY43778.1 - 1.7e-07 30.8 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIY43778.1 - 0.00035 20.5 0.0 0.53 10.2 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KIY43778.1 - 0.00043 19.9 0.0 0.00096 18.7 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY43778.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY43778.1 - 0.014 15.0 0.1 0.034 13.7 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KIY43778.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ras PF00071.22 KIY43779.1 - 6.5e-52 175.4 0.5 2.2e-51 173.7 0.5 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KIY43779.1 - 3e-19 69.4 0.0 5.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY43779.1 - 1.1e-09 38.0 0.6 1.4e-09 37.6 0.1 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY43779.1 - 0.001 18.6 0.2 0.0046 16.5 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Asp PF00026.23 KIY43780.1 - 6.4e-49 167.1 0.0 7.1e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY43780.1 - 9.6e-10 39.0 0.3 5.6e-08 33.2 0.1 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DUF726 PF05277.12 KIY43781.1 - 6.6e-121 403.4 1.9 9.5e-121 402.9 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 KIY43781.1 - 0.022 14.4 0.2 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold NAD_binding_4 PF07993.12 KIY43782.1 - 0.14 11.3 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Male sterility protein ApbA PF02558.16 KIY43783.1 - 7.9e-15 54.8 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KIY43783.1 - 1e-14 54.8 0.0 1e-12 48.4 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.21 KIY43783.1 - 0.0011 18.4 0.0 0.0068 15.8 0.0 1.9 2 0 0 2 2 2 1 ThiF family NAD_binding_7 PF13241.6 KIY43783.1 - 0.024 15.1 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KIY43783.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KIY43783.1 - 0.061 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 KIY43783.1 - 0.083 12.9 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KIY43783.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase F5_F8_type_C PF00754.25 KIY43784.1 - 3.8e-05 23.8 0.0 4.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Aldo_ket_red PF00248.21 KIY43785.1 - 4.2e-38 131.2 0.0 5.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MaoC_dehydratas PF01575.19 KIY43786.1 - 6.6e-28 96.7 0.0 1.2e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIY43786.1 - 0.0083 16.3 0.0 0.028 14.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase AcetylCoA_hydro PF02550.15 KIY43787.1 - 1.2e-47 162.5 0.0 1.8e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KIY43787.1 - 4.6e-42 143.6 0.0 7.4e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AAA_2 PF07724.14 KIY43788.1 - 3.3e-40 138.0 0.0 2.8e-38 131.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIY43788.1 - 2.1e-34 117.6 3.5 7e-34 115.9 0.4 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KIY43788.1 - 1.4e-20 73.1 0.2 1.4e-20 73.1 0.2 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KIY43788.1 - 9.9e-20 71.3 0.1 6e-11 42.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIY43788.1 - 1.8e-16 60.4 0.4 3.6e-10 40.0 0.0 4.1 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY43788.1 - 2e-11 44.6 6.8 3e-05 24.5 0.1 4.9 4 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KIY43788.1 - 8e-08 32.6 2.2 0.0024 18.2 0.0 4.9 5 0 0 5 5 5 1 AAA domain IstB_IS21 PF01695.17 KIY43788.1 - 4.2e-06 26.6 0.0 0.22 11.2 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein ATPase_2 PF01637.18 KIY43788.1 - 2.3e-05 24.4 0.4 0.3 11.0 0.0 4.1 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KIY43788.1 - 3.4e-05 23.3 0.2 0.3 10.4 0.0 3.2 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KIY43788.1 - 6.1e-05 22.8 0.6 1.1 9.0 0.0 3.5 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIY43788.1 - 7.9e-05 23.2 0.0 0.31 11.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KIY43788.1 - 0.00016 21.4 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIY43788.1 - 0.0002 22.0 3.7 1.4 9.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KIY43788.1 - 0.0003 20.8 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY43788.1 - 0.00069 19.2 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 KIY43788.1 - 0.00076 19.2 0.1 0.029 14.1 0.1 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 KIY43788.1 - 0.0011 19.3 2.3 0.4 10.9 0.0 3.9 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 KIY43788.1 - 0.0014 18.9 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIY43788.1 - 0.0025 17.7 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KIY43788.1 - 0.0033 17.9 0.8 2.4 8.7 0.0 3.1 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.22 KIY43788.1 - 0.0034 17.8 0.0 3 8.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 KIY43788.1 - 0.0044 16.7 0.0 5 7.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_19 PF13245.6 KIY43788.1 - 0.0088 16.4 0.2 0.38 11.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY43788.1 - 0.0092 16.1 0.0 4.9 7.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY43788.1 - 0.028 14.4 0.3 0.92 9.4 0.0 2.7 2 1 0 2 2 2 0 NACHT domain TsaE PF02367.17 KIY43788.1 - 0.028 14.4 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KIY43788.1 - 0.045 13.7 0.0 7.1 6.5 0.0 3.1 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 KIY43788.1 - 0.05 13.2 0.9 1.3 8.6 0.0 3.4 4 1 0 4 4 3 0 AAA domain ResIII PF04851.15 KIY43788.1 - 0.051 13.6 0.2 8.5 6.3 0.0 3.1 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KIY43788.1 - 0.068 12.6 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KIY43788.1 - 0.068 12.9 3.5 0.93 9.2 0.0 3.2 3 1 0 3 3 3 0 AAA domain MCM PF00493.23 KIY43788.1 - 0.073 12.2 0.1 1.4 7.9 0.0 2.6 2 1 0 2 2 2 0 MCM P-loop domain AAA_21 PF13304.6 KIY43788.1 - 1.6 8.4 5.0 6 6.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Oxidored-like PF09791.9 KIY43789.1 - 2.8e-18 65.3 2.8 4.1e-18 64.8 1.2 1.9 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Pkinase PF00069.25 KIY43791.1 - 8.9e-49 166.2 0.0 1.9e-48 165.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43791.1 - 6.7e-19 68.2 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIY43791.1 - 0.0017 18.0 0.2 0.005 16.5 0.1 1.7 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 KIY43791.1 - 0.025 13.9 0.4 6.2 6.0 0.1 2.2 2 0 0 2 2 2 0 Kinase-like HTH_16 PF12645.7 KIY43791.1 - 0.072 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Pox_ser-thr_kin PF05445.11 KIY43791.1 - 0.089 11.7 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pyr_redox_2 PF07992.14 KIY43792.1 - 1.5e-48 165.5 0.2 1.9e-48 165.2 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KIY43792.1 - 6.1e-17 61.4 0.0 1.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KIY43792.1 - 6e-13 49.2 0.1 6e-11 42.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KIY43792.1 - 5.8e-08 33.2 0.0 1.3e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal HI0933_like PF03486.14 KIY43792.1 - 0.00047 19.0 0.0 3.1 6.4 0.0 3.5 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 KIY43792.1 - 0.034 14.4 0.0 7.1 7.0 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Mannosyl_trans3 PF11051.8 KIY43792.1 - 0.056 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative IMS PF00817.20 KIY43793.1 - 3.8e-38 130.8 0.0 6e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KIY43793.1 - 4.8e-17 62.7 0.0 3e-16 60.2 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KIY43793.1 - 3.6e-08 32.9 4.1 8.5e-05 22.1 1.5 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KIY43793.1 - 0.0013 18.9 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-ribbon_3 PF13248.6 KIY43793.1 - 0.094 12.2 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain CpXC PF14353.6 KIY43793.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 CpXC protein zf-Mss51 PF13824.6 KIY43793.1 - 0.11 12.6 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Asp PF00026.23 KIY43794.1 - 8.2e-68 229.1 6.0 9.9e-68 228.9 6.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY43794.1 - 9.3e-11 42.3 2.5 1.3e-08 35.3 2.5 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY43794.1 - 0.0049 17.5 0.8 0.88 10.3 0.0 3.7 2 1 1 3 3 3 1 Aspartyl protease ECH_1 PF00378.20 KIY43795.1 - 2e-26 92.8 0.0 3.1e-26 92.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY43795.1 - 2.1e-10 40.6 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HTH_24 PF13412.6 KIY43795.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KIY43795.1 - 0.031 14.1 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Peptidase_S49 PF01343.18 KIY43795.1 - 0.06 13.3 0.0 2.9 7.8 0.0 2.4 2 1 0 2 2 2 0 Peptidase family S49 AAA PF00004.29 KIY43796.1 - 7.5e-42 142.9 0.0 1.1e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY43796.1 - 8.9e-07 29.4 0.1 2.2e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KIY43796.1 - 1.9e-06 28.1 0.0 4.9e-06 26.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KIY43796.1 - 7.9e-05 22.7 0.0 0.00073 19.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KIY43796.1 - 8.2e-05 22.4 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KIY43796.1 - 0.0005 20.4 0.1 0.021 15.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY43796.1 - 0.0014 18.8 0.0 0.0018 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY43796.1 - 0.0019 18.8 0.0 0.0027 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KIY43796.1 - 0.0053 16.5 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KIY43796.1 - 0.007 16.1 0.0 0.022 14.5 0.0 1.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KIY43796.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KIY43796.1 - 0.016 15.4 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIY43796.1 - 0.028 14.0 0.2 0.11 12.1 0.1 1.7 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 KIY43796.1 - 0.029 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.13 KIY43796.1 - 0.03 13.5 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KIY43796.1 - 0.04 14.3 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KIY43796.1 - 0.04 13.6 0.0 0.36 10.5 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 KIY43796.1 - 0.041 13.9 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIY43796.1 - 0.064 12.6 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 KIY43796.1 - 0.068 13.1 0.1 0.17 11.8 0.1 1.8 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 KIY43796.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KIY43796.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KIY43796.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KIY43796.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KIY43796.1 - 0.2 10.8 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) tRNA-synt_1g PF09334.11 KIY43798.1 - 1.2e-94 317.3 0.0 4.3e-94 315.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIY43798.1 - 1e-23 83.5 1.0 6e-13 47.9 0.0 4.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KIY43798.1 - 3.5e-13 49.6 0.0 3.1e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KIY43798.1 - 0.0029 16.6 0.0 0.0068 15.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (K) Glu-tRNAGln PF02686.15 KIY43798.1 - 0.026 14.8 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit RhoGEF PF00621.20 KIY43799.1 - 1.2e-31 110.3 0.4 2e-31 109.6 0.4 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 KIY43799.1 - 1.7e-24 86.9 0.0 3.6e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIY43799.1 - 0.02 15.0 0.0 0.26 11.4 0.0 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 KIY43799.1 - 0.035 14.6 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 PH domain Steroid_dh PF02544.16 KIY43800.1 - 2.1e-36 125.2 1.9 2.1e-36 125.2 1.9 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KIY43800.1 - 4.2e-05 23.2 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2456 PF10445.9 KIY43800.1 - 0.018 15.1 1.8 0.028 14.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) DUF1295 PF06966.12 KIY43800.1 - 0.023 14.2 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) CAS_CSE1 PF03378.15 KIY43801.1 - 1.5e-116 389.5 1.8 2.5e-116 388.8 1.8 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KIY43801.1 - 1.1e-90 304.1 0.0 3.1e-90 302.7 0.0 1.8 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.19 KIY43801.1 - 3e-11 43.1 0.1 1.3e-10 41.1 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KIY43801.1 - 7.8e-05 22.8 0.5 0.005 16.9 0.1 3.6 3 0 0 3 3 3 1 Exportin 1-like protein CLASP_N PF12348.8 KIY43801.1 - 0.17 11.4 0.4 5.5 6.5 0.1 3.2 3 0 0 3 3 3 0 CLASP N terminal UCH PF00443.29 KIY43801.1 - 0.18 11.3 0.0 0.85 9.1 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_3 PF07859.13 KIY43802.1 - 1.8e-27 96.6 0.0 2.3e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY43802.1 - 1.7e-10 40.3 0.0 3.6e-10 39.3 0.0 1.4 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KIY43802.1 - 0.0084 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Arv1 PF04161.13 KIY43803.1 - 8.2e-13 49.0 0.0 1.3e-12 48.3 0.0 1.3 1 1 0 1 1 1 1 Arv1-like family DUF4106 PF13388.6 KIY43804.1 - 0.11 11.8 1.9 0.23 10.7 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF3391 PF11871.8 KIY43804.1 - 9 6.8 8.0 46 4.5 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) DUF410 PF04190.13 KIY43805.1 - 1.1e-75 254.7 0.0 1.4e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_7 PF13176.6 KIY43805.1 - 0.02 14.9 1.0 7.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM PF10378.9 KIY43805.1 - 0.086 12.6 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Putative RRM domain TPR_2 PF07719.17 KIY43805.1 - 0.14 12.3 0.1 6.7 7.1 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Gti1_Pac2 PF09729.9 KIY43806.1 - 4.5e-42 144.2 2.1 1.6e-40 139.1 2.1 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family Ank_4 PF13637.6 KIY43807.1 - 3e-16 59.6 0.0 1.1e-10 41.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY43807.1 - 7.1e-13 48.5 0.0 3.4e-07 30.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY43807.1 - 2.6e-12 46.6 0.0 5.4e-08 32.9 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KIY43807.1 - 2.5e-11 44.0 0.0 4.1e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY43807.1 - 5.3e-10 38.7 0.0 1.6e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Multi_ubiq PF14452.6 KIY43807.1 - 0.13 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Multiubiquitin Ank PF00023.30 KIY43808.1 - 1.8e-14 53.4 1.5 0.00026 21.3 0.2 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KIY43808.1 - 3.3e-14 53.0 0.3 2.9e-09 37.3 0.0 2.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY43808.1 - 4.1e-13 49.3 3.5 0.00027 21.2 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY43808.1 - 1.4e-12 46.6 0.2 0.001 19.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KIY43808.1 - 1.5e-12 47.9 0.0 3.8e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C2H2 PF00096.26 KIY43809.1 - 1.7e-09 37.6 13.0 1.8e-07 31.2 4.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY43809.1 - 3.4e-08 33.5 11.1 1.6e-06 28.2 3.2 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY43809.1 - 3.8e-06 27.3 11.4 8.6e-06 26.2 3.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KIY43809.1 - 0.0029 18.0 7.3 0.0065 16.8 1.9 2.4 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KIY43809.1 - 0.038 13.7 4.1 0.077 12.8 4.1 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KIY43809.1 - 0.049 13.5 0.3 0.049 13.5 0.3 1.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KIY43809.1 - 0.16 12.3 0.8 0.16 12.3 0.8 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KIY43809.1 - 1.1 9.4 11.6 1.1 9.3 7.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger WGG PF10273.9 KIY43810.1 - 5.9e-27 94.2 0.2 9.4e-27 93.5 0.2 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Inhibitor_I53 PF11714.8 KIY43810.1 - 0.48 10.7 2.2 0.89 9.8 0.9 2.0 1 1 1 2 2 2 0 Thrombin inhibitor Madanin CLP1_P PF16575.5 KIY43811.1 - 1.8e-34 119.2 0.0 5.2e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 KIY43811.1 - 0.00028 20.3 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family Patatin PF01734.22 KIY43811.1 - 0.007 16.6 0.1 0.015 15.5 0.1 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase AAA_14 PF13173.6 KIY43811.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CobU PF02283.16 KIY43811.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ECM11 PF15463.6 KIY43812.1 - 1.3e-05 25.8 0.0 2.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Extracellular mutant protein 11 WD40 PF00400.32 KIY43814.1 - 1.6e-28 98.4 9.1 6e-07 30.1 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY43814.1 - 8.3e-13 48.4 0.0 1.1e-05 25.7 0.0 5.4 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY43814.1 - 0.00056 19.0 0.0 0.18 10.8 0.0 2.7 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIY43814.1 - 0.0041 16.5 0.0 16 4.7 0.0 3.5 4 0 0 4 4 4 3 WD40-like domain zf-HIT PF04438.16 KIY43815.1 - 7.2e-07 29.0 8.3 1.4e-06 28.0 8.3 1.5 1 0 0 1 1 1 1 HIT zinc finger Cys_Met_Meta_PP PF01053.20 KIY43816.1 - 1.7e-129 431.7 0.0 2.2e-129 431.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 KIY43816.1 - 1.1e-14 54.4 0.1 1.1e-14 54.4 0.1 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIY43816.1 - 3.1e-07 30.7 0.0 8.7e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DegT_DnrJ_EryC1 PF01041.17 KIY43816.1 - 0.00064 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GalKase_gal_bdg PF10509.9 KIY43816.1 - 0.00072 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.11 KIY43816.1 - 0.0025 16.4 0.0 0.015 13.8 0.0 2.0 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KIY43816.1 - 0.045 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase Chlorosome_CsmC PF11098.8 KIY43816.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Chlorosome envelope protein C Transketolase_N PF00456.21 KIY43817.1 - 1.7e-15 56.9 1.8 5e-14 52.0 1.7 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KIY43817.1 - 9.7e-08 31.9 0.0 2.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KIY43817.1 - 5.3e-06 26.2 0.1 1.7e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KIY43817.1 - 1.1e-05 25.2 0.2 5.6e-05 23.0 0.2 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KIY43817.1 - 0.00043 19.3 0.1 0.00078 18.5 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Phosphatase PF15698.5 KIY43817.1 - 0.042 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphatase RabGAP-TBC PF00566.18 KIY43819.1 - 1.8e-47 161.8 0.0 2.9e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Alpha-amylase PF00128.24 KIY43820.1 - 5.2e-21 75.6 0.0 1.7e-20 73.9 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KIY43820.1 - 0.11 10.7 0.1 1.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 Aminotran_1_2 PF00155.21 KIY43821.1 - 5.7e-48 163.9 0.0 2.9e-42 145.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIY43821.1 - 0.0027 17.0 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KIY43821.1 - 0.0057 15.4 0.0 0.0099 14.6 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 KIY43821.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Aldo_ket_red PF00248.21 KIY43822.1 - 2.6e-39 135.2 0.0 8.2e-37 127.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Alpha-amylase PF00128.24 KIY43823.1 - 1.2e-48 166.4 0.8 5.8e-48 164.2 0.8 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIY43823.1 - 2.2e-16 59.9 0.3 6.1e-16 58.5 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Thioredoxin PF00085.20 KIY43825.1 - 6.6e-56 186.7 0.1 2.5e-27 94.9 0.1 2.5 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.12 KIY43825.1 - 6.1e-22 78.3 0.0 1.4e-21 77.2 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KIY43825.1 - 1.8e-17 63.8 0.2 3.3e-08 33.9 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KIY43825.1 - 5.8e-15 55.4 0.0 2.8e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KIY43825.1 - 1.4e-10 41.3 0.1 0.0011 19.2 0.1 3.7 2 2 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KIY43825.1 - 6.6e-10 39.0 0.0 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 KIY43825.1 - 4.2e-09 36.5 0.0 0.002 18.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like TraF PF13728.6 KIY43825.1 - 2e-05 24.5 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KIY43825.1 - 0.00017 21.3 0.8 0.22 11.2 0.1 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.6 KIY43825.1 - 0.00027 20.9 0.0 0.84 9.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Glutaredoxin PF00462.24 KIY43825.1 - 0.00032 20.9 3.1 0.0073 16.5 0.1 3.2 2 2 0 2 2 2 1 Glutaredoxin Thioredoxin_4 PF13462.6 KIY43825.1 - 0.00075 19.7 1.1 0.49 10.5 0.1 3.3 3 1 1 4 4 4 1 Thioredoxin HyaE PF07449.11 KIY43825.1 - 0.002 18.0 0.0 0.46 10.5 0.0 2.8 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KIY43825.1 - 0.011 15.4 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin DUF836 PF05768.14 KIY43825.1 - 0.016 15.6 0.0 2.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) UCH_1 PF13423.6 KIY43825.1 - 0.067 12.8 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase SMC_N PF02463.19 KIY43829.1 - 2e-27 96.1 0.0 2.3e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY43829.1 - 0.0078 16.1 0.0 0.0097 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KIY43829.1 - 0.021 15.1 0.0 0.058 13.6 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF2326 PF10088.9 KIY43829.1 - 0.098 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) Metallophos PF00149.28 KIY43830.1 - 4.1e-07 30.7 0.2 5.9e-07 30.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase OPT PF03169.15 KIY43831.1 - 1.5e-120 403.8 42.5 1.6e-120 403.6 42.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GREB1 PF15782.5 KIY43832.1 - 0.42 7.7 9.7 0.48 7.5 9.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TOM13 PF08219.11 KIY43832.1 - 0.43 10.6 1.1 34 4.5 0.8 2.6 2 1 0 2 2 2 0 Outer membrane protein TOM13 Plasmodium_Vir PF05795.11 KIY43832.1 - 0.8 9.1 6.0 0.84 9.0 6.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RIFIN PF02009.16 KIY43832.1 - 0.94 9.3 4.6 1.2 9.0 4.6 1.1 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 KIY43832.1 - 3.7 6.0 15.0 4.3 5.8 15.0 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 KIY43832.1 - 4.1 6.5 24.5 5.2 6.1 24.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 KIY43832.1 - 5.5 5.7 15.6 6.6 5.5 15.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 KIY43832.1 - 7.1 4.6 7.7 8.2 4.4 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAP1 PF08601.10 KIY43832.1 - 7.5 6.2 24.0 11 5.6 24.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 CS PF04969.16 KIY43833.1 - 0.00044 21.2 0.0 0.00086 20.3 0.0 1.4 1 0 0 1 1 1 1 CS domain SecD-TM1 PF13721.6 KIY43834.1 - 0.15 12.5 10.7 0.19 12.2 2.2 3.3 2 1 1 3 3 3 0 SecD export protein N-terminal TM region YabA PF06156.13 KIY43834.1 - 1.1 9.9 40.3 0.12 13.0 5.9 5.7 1 1 4 5 5 5 0 Initiation control protein YabA Uso1_p115_C PF04871.13 KIY43834.1 - 3.5 8.0 54.2 57 4.1 1.8 5.0 3 1 1 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region BRE1 PF08647.11 KIY43834.1 - 5.6 7.1 43.8 0.22 11.6 12.0 4.8 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase Sugarporin_N PF11471.8 KIY43835.1 - 0.02 14.8 1.2 0.06 13.3 1.2 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Stathmin PF00836.19 KIY43835.1 - 0.21 11.5 0.2 0.7 9.9 0.2 1.9 1 0 0 1 1 1 0 Stathmin family Erg28 PF03694.13 KIY43836.1 - 1.1e-42 144.8 0.9 1.4e-42 144.6 0.9 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF1467 PF07330.12 KIY43836.1 - 0.0018 18.2 0.4 0.0037 17.2 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1467) Na_Ca_ex PF01699.24 KIY43837.1 - 2.7e-24 85.8 22.8 6.7e-20 71.6 15.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein KilA-N PF04383.13 KIY43841.1 - 0.015 15.2 0.0 0.053 13.4 0.0 1.8 1 1 0 1 1 1 0 KilA-N domain SGL PF08450.12 KIY43842.1 - 2.4e-05 24.0 0.0 0.0001 22.0 0.0 2.0 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KIY43842.1 - 0.074 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Lactonase PF10282.9 KIY43842.1 - 0.12 11.6 0.0 0.69 9.1 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 KIY43842.1 - 0.14 12.4 0.0 22 5.4 0.0 2.6 2 0 0 2 2 2 0 Arylesterase Ge1_WD40 PF16529.5 KIY43842.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Str_synth PF03088.16 KIY43842.1 - 0.18 12.0 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 Strictosidine synthase MFS_1 PF07690.16 KIY43843.1 - 3.4e-14 52.6 40.3 5.5e-08 32.1 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Vps39_1 PF10366.9 KIY43844.1 - 4.1e-27 94.6 0.0 3.7e-26 91.5 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KIY43844.1 - 1.7e-22 79.9 0.1 4.1e-22 78.7 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KIY43844.1 - 9e-16 58.3 0.0 2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 KIY43844.1 - 2.8e-12 46.7 1.7 3.8e-11 43.0 1.2 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40_like PF17005.5 KIY43844.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain TPR_1 PF00515.28 KIY43844.1 - 0.025 14.4 4.8 13 5.8 1.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY43844.1 - 0.073 13.1 5.9 6.8 7.0 0.3 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY43844.1 - 3.1 8.2 6.7 13 6.2 0.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY43844.1 - 7.1 7.6 9.0 1.5 9.7 0.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.7 KIY43845.1 - 1.1e-07 31.6 0.1 2.1e-06 27.5 0.0 2.9 2 0 0 2 2 2 1 F-box-like Lipase_3 PF01764.25 KIY43846.1 - 2.8e-08 33.7 0.0 9.7e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Cyto_heme_lyase PF01265.17 KIY43847.1 - 3.9e-43 148.1 2.4 1.9e-41 142.5 2.4 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Brix PF04427.18 KIY43848.1 - 2.1e-43 148.7 0.0 2.9e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain PPL5 PF18168.1 KIY43848.1 - 0.0095 15.3 5.5 0.014 14.7 5.5 1.3 1 0 0 1 1 1 1 Prim-pol family 5 TFIIA PF03153.13 KIY43848.1 - 0.22 11.5 20.7 0.29 11.1 20.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AP-5_subunit_s1 PF15001.6 KIY43848.1 - 0.92 9.5 7.9 1.6 8.7 7.9 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 MCM_bind PF09739.9 KIY43848.1 - 3.4 6.0 8.8 5 5.4 8.8 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor XRN_M PF17846.1 KIY43848.1 - 4 6.3 10.9 6.4 5.6 10.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Nop25 PF09805.9 KIY43848.1 - 4.1 7.9 28.5 9.3 6.7 28.5 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF953 PF06110.11 KIY43850.1 - 5.3e-17 61.5 0.0 6.4e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 KIY43850.1 - 0.0015 18.5 0.0 0.0021 18.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIY43850.1 - 0.034 14.5 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 KIY43850.1 - 0.058 13.8 0.0 0.081 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF3088 PF11287.8 KIY43850.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) SCHIP-1 PF10148.9 KIY43851.1 - 0.51 9.9 8.2 2.3 7.8 8.1 2.0 1 1 0 1 1 1 0 Schwannomin-interacting protein 1 PRMT5 PF05185.16 KIY43852.1 - 1.6e-65 220.2 0.0 3.2e-65 219.2 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KIY43852.1 - 2.3e-61 207.2 0.1 4.7e-61 206.2 0.1 1.4 1 1 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KIY43852.1 - 3.3e-59 199.7 0.0 4.8e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 KIY43852.1 - 0.00039 21.1 0.0 0.0011 19.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY43852.1 - 0.0075 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KIY43852.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein WLM PF08325.10 KIY43853.1 - 3.3e-31 108.9 0.2 2.4e-30 106.0 0.2 2.0 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KIY43853.1 - 0.00018 21.6 0.3 0.00033 20.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 KIY43853.1 - 0.00021 20.5 0.7 0.00049 19.3 0.7 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SprT-like PF10263.9 KIY43853.1 - 0.057 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 SprT-like family DZR PF12773.7 KIY43853.1 - 0.13 12.3 0.6 0.28 11.2 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon TMEM151 PF14857.6 KIY43854.1 - 0.01 14.8 2.8 0.012 14.6 2.8 1.0 1 0 0 1 1 1 0 TMEM151 family Dehydrin PF00257.19 KIY43854.1 - 0.45 11.0 14.8 0.57 10.7 14.8 1.1 1 0 0 1 1 1 0 Dehydrin Tmemb_cc2 PF10267.9 KIY43854.1 - 3.8 6.5 3.9 4.5 6.3 3.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Apt1 PF10351.9 KIY43854.1 - 4.1 6.2 7.3 4.5 6.0 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KIY43854.1 - 4.4 5.7 7.7 5.7 5.4 7.7 1.2 1 0 0 1 1 1 0 Macoilin family PTR2 PF00854.21 KIY43855.1 - 1.1e-78 264.8 10.7 1.5e-78 264.4 10.7 1.1 1 0 0 1 1 1 1 POT family FKBP_C PF00254.28 KIY43856.1 - 4.3e-27 94.3 0.0 5.1e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GATase PF00117.28 KIY43858.1 - 4.6e-08 33.1 0.0 2.4e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I WD40 PF00400.32 KIY43859.1 - 7.6e-18 64.6 11.6 8.7e-05 23.2 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY43859.1 - 3.1e-09 37.0 0.0 0.0043 17.3 0.0 4.1 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIY43859.1 - 0.0086 14.4 0.0 1.8 6.8 0.0 2.2 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIY43859.1 - 0.026 13.5 0.1 0.17 10.8 0.0 2.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIY43859.1 - 0.045 13.1 0.0 0.52 9.6 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KIY43860.1 - 1.3e-24 85.9 5.5 1.3e-05 25.9 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY43860.1 - 3.5e-11 43.2 0.0 0.0022 18.2 0.0 4.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY43860.1 - 0.0035 16.7 0.0 0.091 12.1 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 KIY43860.1 - 0.011 15.7 0.0 0.67 9.8 0.0 2.9 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIY43860.1 - 0.014 13.7 0.0 1.2 7.4 0.0 2.5 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_3 PF15911.5 KIY43860.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIY43860.1 - 0.13 11.2 0.1 2.7 6.8 0.0 2.8 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIY43860.1 - 0.31 11.6 2.9 36 5.0 0.1 4.5 4 1 0 4 4 4 0 PQQ-like domain PFK PF00365.20 KIY43861.1 - 4.7e-180 597.1 0.0 2.1e-100 335.7 0.0 2.9 2 1 0 2 2 2 2 Phosphofructokinase SBDS_C PF09377.10 KIY43861.1 - 0.025 14.6 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 SBDS protein C-terminal domain UVR PF02151.19 KIY43861.1 - 0.21 11.4 0.1 0.49 10.2 0.1 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif DUF4149 PF13664.6 KIY43862.1 - 8.4 6.8 9.0 2.7 8.4 1.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4149) MFS_1 PF07690.16 KIY43864.1 - 1.1e-12 47.6 29.3 2.9e-12 46.2 19.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Ricin_B_lectin PF00652.22 KIY43865.1 - 1.7e-19 70.3 3.1 1.7e-19 70.3 3.1 2.4 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIY43865.1 - 3.1e-09 37.4 7.2 6.9e-05 23.5 0.6 3.4 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ribosomal_L4 PF00573.22 KIY43866.1 - 6.4e-40 136.9 1.0 1.2e-39 136.0 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KIY43866.1 - 7.4e-30 102.8 2.3 7.4e-30 102.8 2.3 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Cupin_1 PF00190.22 KIY43867.1 - 8.5e-37 126.1 0.0 4.3e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KIY43867.1 - 6.8e-29 99.4 0.7 5.8e-14 51.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KIY43867.1 - 3.6e-09 36.2 0.0 0.00012 21.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KIY43867.1 - 6.7e-08 32.5 0.3 1.1e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KIY43867.1 - 3.4e-05 23.8 0.0 0.00055 19.9 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.12 KIY43867.1 - 0.0006 19.4 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein ARD PF03079.14 KIY43867.1 - 0.00083 19.6 0.0 0.046 13.9 0.0 2.2 2 0 0 2 2 2 1 ARD/ARD' family DUF2475 PF10629.9 KIY43867.1 - 0.074 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) DcpS_C PF11969.8 KIY43868.1 - 1.2e-18 67.7 0.1 1.7e-18 67.2 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIY43868.1 - 3.5e-08 34.1 3.3 3.2e-07 31.0 3.3 2.1 1 1 0 1 1 1 1 HIT domain UCH PF00443.29 KIY43869.1 - 1.8e-52 178.4 0.6 2.5e-52 177.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY43869.1 - 3e-23 82.9 7.2 1.1e-22 81.1 7.2 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIY43869.1 - 1.8e-12 47.4 9.9 1.8e-12 47.4 9.9 3.1 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein ATP-synt_E PF05680.12 KIY43869.1 - 9.7 6.6 9.9 18 5.7 9.9 1.4 1 0 0 1 1 1 0 ATP synthase E chain Thg1 PF04446.12 KIY43870.1 - 3.7e-48 162.7 0.1 5.7e-48 162.1 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KIY43870.1 - 2.1e-41 140.9 1.3 4e-41 140.0 0.7 1.7 1 1 0 1 1 1 1 Thg1 C terminal domain FA_hydroxylase PF04116.13 KIY43871.1 - 8.9e-23 81.1 26.9 1.2e-22 80.7 21.2 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily ERG4_ERG24 PF01222.17 KIY43872.1 - 2e-130 435.5 24.3 2.2e-130 435.3 24.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIY43872.1 - 0.00013 21.6 1.7 0.00013 21.6 1.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIY43872.1 - 0.0053 17.2 0.1 0.032 14.6 0.1 2.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Glyco_transf_20 PF00982.21 KIY43873.1 - 2.6e-181 603.5 0.0 4e-181 602.8 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KIY43873.1 - 8.8e-05 22.9 0.0 0.0002 21.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KIY43873.1 - 0.0072 15.9 0.4 1.9 8.0 0.0 2.5 2 1 0 2 2 2 2 Glycosyl transferases group 1 DnaG_DnaB_bind PF08278.11 KIY43873.1 - 0.18 12.4 0.1 55 4.4 0.0 2.9 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding Glyco_hydro_35 PF01301.19 KIY43874.1 - 9.3e-74 248.9 0.1 1.3e-73 248.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIY43874.1 - 6e-57 191.2 0.4 1.9e-30 105.8 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIY43874.1 - 1.1e-33 116.5 0.0 1.8e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIY43874.1 - 2.5e-18 65.4 0.0 1e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KIY43874.1 - 0.00035 20.0 0.6 0.0037 16.6 0.6 2.0 1 1 0 1 1 1 1 Beta-galactosidase PIF1 PF05970.14 KIY43877.1 - 0.0088 15.2 0.0 0.42 9.7 0.0 2.7 2 1 0 3 3 3 1 PIF1-like helicase FGAR-AT_N PF18076.1 KIY43877.1 - 0.075 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Oberon_cc PF16312.5 KIY43877.1 - 0.084 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil region of Oberon YdiH PF15930.5 KIY43877.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function CLTH PF10607.9 KIY43878.1 - 0.0072 16.2 0.1 0.0094 15.8 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain OB_NTP_bind PF07717.16 KIY43878.1 - 0.1 12.9 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold Helitron_like_N PF14214.6 KIY43879.1 - 4.4e-22 79.2 0.1 5.7e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SAM_decarbox PF01536.16 KIY43880.1 - 3.3e-21 75.7 0.0 3.8e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase MBOAT PF03062.19 KIY43881.1 - 7e-51 173.6 31.8 1.1e-50 173.0 31.8 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family TrbC PF04956.13 KIY43881.1 - 0.00091 19.4 0.2 0.00091 19.4 0.2 2.9 3 1 1 4 4 4 1 TrbC/VIRB2 family GerA PF03323.13 KIY43881.1 - 0.44 8.9 2.2 0.69 8.3 1.3 1.6 1 1 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein BAAT_C PF08840.11 KIY43882.1 - 0.087 12.7 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CENP-H PF05837.12 KIY43882.1 - 2.6 8.5 8.4 6.6 7.2 8.4 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4350 PF14258.6 KIY43884.1 - 0.023 15.1 0.2 0.51 10.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) TauD PF02668.16 KIY43885.1 - 1.9e-51 175.5 0.3 2.4e-51 175.1 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NUDIX PF00293.28 KIY43886.1 - 8.5e-12 45.2 0.0 6.8e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain AAA PF00004.29 KIY43887.1 - 5.8e-41 140.0 0.0 1.3e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY43887.1 - 8.9e-06 25.4 0.1 2.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KIY43887.1 - 5.2e-05 23.3 0.0 0.00019 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY43887.1 - 7.4e-05 23.0 0.0 0.0048 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KIY43887.1 - 0.0002 21.5 0.0 0.00074 19.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KIY43887.1 - 0.00074 19.9 0.1 0.014 15.8 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KIY43887.1 - 0.00085 18.6 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KIY43887.1 - 0.0059 16.4 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KIY43887.1 - 0.012 15.2 0.0 0.032 13.7 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KIY43887.1 - 0.014 15.7 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY43887.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KIY43887.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KIY43887.1 - 0.063 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KIY43887.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIY43887.1 - 0.067 13.7 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIY43887.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KIY43887.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KIY43887.1 - 0.096 12.4 0.1 0.73 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIY43887.1 - 0.11 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KIY43887.1 - 0.14 12.2 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KIY43887.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF5636 PF18686.1 KIY43887.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5636) DUF4350 PF14258.6 KIY43888.1 - 0.0013 19.1 0.1 0.66 10.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4350) DUF563 PF04577.14 KIY43889.1 - 9e-17 61.9 0.1 1.5e-15 57.9 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF563) Cnd1 PF12717.7 KIY43890.1 - 2.4e-50 170.7 4.9 7.6e-48 162.6 0.3 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KIY43890.1 - 8.8e-32 110.2 0.0 8.8e-32 110.2 0.0 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 KIY43890.1 - 0.00012 22.0 3.4 0.25 11.7 0.0 5.2 7 0 0 7 7 7 1 HEAT repeat PqqD PF05402.12 KIY43890.1 - 0.022 15.0 0.1 1.6 9.1 0.0 3.7 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) G0-G1_switch_2 PF15103.6 KIY43890.1 - 0.036 14.5 0.0 0.036 14.5 0.0 4.4 4 1 1 5 5 5 0 G0/G1 switch protein 2 Cnd3 PF12719.7 KIY43890.1 - 0.1 11.8 1.9 0.18 11.0 0.4 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain CDC45 PF02724.14 KIY43890.1 - 0.12 10.7 14.2 0.26 9.6 14.2 1.5 1 0 0 1 1 1 0 CDC45-like protein HEAT_EZ PF13513.6 KIY43890.1 - 2.1 9.0 6.1 2.8 8.6 0.0 4.0 5 0 0 5 5 5 0 HEAT-like repeat Ribosomal_L17 PF01196.19 KIY43890.1 - 6.3 7.8 7.5 6.8 7.7 0.1 4.2 4 0 0 4 4 4 0 Ribosomal protein L17 RFC1 PF08519.12 KIY43891.1 - 1.5e-56 190.9 0.0 1.4e-54 184.5 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KIY43891.1 - 3.2e-13 49.9 0.0 8e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KIY43891.1 - 2.8e-09 37.5 0.0 8.4e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIY43891.1 - 0.001 19.1 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KIY43891.1 - 0.0049 16.6 1.0 0.016 15.0 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KIY43891.1 - 0.022 15.3 0.0 0.073 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIY43891.1 - 0.026 14.9 0.1 0.069 13.5 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIY43891.1 - 0.035 14.4 0.4 0.47 10.7 0.4 2.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KIY43891.1 - 0.061 13.8 0.1 14 6.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KIY43891.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIY43891.1 - 0.1 12.5 0.1 0.31 10.9 0.1 1.8 2 0 0 2 2 2 0 NTPase AAA_assoc_2 PF16193.5 KIY43891.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain RuvB_N PF05496.12 KIY43891.1 - 0.16 11.7 0.1 0.45 10.2 0.1 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Vta1 PF04652.16 KIY43892.1 - 3e-45 153.7 0.1 3.9e-45 153.4 0.1 1.1 1 0 0 1 1 1 1 Vta1 like WD40 PF00400.32 KIY43893.1 - 5e-16 58.8 6.5 0.0027 18.5 0.2 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KIY43893.1 - 0.011 14.4 0.1 0.046 12.4 0.2 2.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 RNB PF00773.19 KIY43894.1 - 1.5e-47 162.5 0.0 5.1e-47 160.8 0.0 1.8 1 1 0 1 1 1 1 RNB domain HLH PF00010.26 KIY43895.1 - 1.4e-06 28.2 0.0 3.2e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain eIF3_subunit PF08597.10 KIY43896.1 - 9e-56 189.5 24.7 1e-55 189.3 24.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit COQ9 PF08511.11 KIY43897.1 - 5.2e-11 42.2 0.0 8.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 COQ9 Acetyltransf_3 PF13302.7 KIY43897.1 - 0.074 13.7 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KIY43898.1 - 2.7e-44 151.5 0.0 6.5e-26 91.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43898.1 - 5.3e-20 71.8 0.0 5.6e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY43898.1 - 7.1e-06 25.5 0.0 0.0057 16.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KIY43898.1 - 0.0017 18.3 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family P21-Arc PF04062.14 KIY43898.1 - 0.13 12.3 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 ARP2/3 complex ARPC3 (21 kDa) subunit DUF616 PF04765.13 KIY43899.1 - 0.032 13.5 0.0 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF616) Glyco_transf_8 PF01501.20 KIY43899.1 - 0.035 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 O-FucT PF10250.9 KIY43900.1 - 4.1e-12 46.5 0.0 7.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ACT PF01842.25 KIY43900.1 - 0.21 11.4 0.1 0.64 9.9 0.0 1.9 2 0 0 2 2 2 0 ACT domain NIF PF03031.18 KIY43901.1 - 4.4e-16 59.0 0.0 6.8e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KIY43901.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Mt_ATP_synt PF15704.5 KIY43901.1 - 0.17 11.7 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit F_actin_cap_B PF01115.17 KIY43902.1 - 4.1e-107 357.2 0.0 4.7e-107 357.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DnaJ_C PF01556.18 KIY43903.1 - 1.4e-41 142.0 0.1 1.9e-41 141.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY43903.1 - 7.2e-27 93.3 2.0 1.1e-26 92.7 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KIY43903.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 A repeated domain in UCH-protein DUF202 PF02656.15 KIY43904.1 - 6.1e-14 52.2 2.5 6.1e-14 52.2 2.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CoA_binding_3 PF13727.6 KIY43904.1 - 0.084 12.9 1.3 0.12 12.4 1.3 1.2 1 0 0 1 1 1 0 CoA-binding domain p450 PF00067.22 KIY43905.1 - 3.4e-78 263.5 0.0 4.7e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1641 PF07849.11 KIY43905.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) WD40 PF00400.32 KIY43906.1 - 6.7e-42 140.7 23.9 1.2e-07 32.3 0.1 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY43906.1 - 2.5e-19 69.4 0.1 0.00011 22.4 0.1 6.0 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY43906.1 - 3.3e-08 33.7 0.2 0.0018 18.2 0.0 2.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIY43906.1 - 8.2e-07 28.3 1.7 0.082 11.9 0.1 4.0 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIY43906.1 - 0.01 14.6 0.1 1.4 7.6 0.1 3.0 2 1 1 3 3 3 0 Nup133 N terminal like Coatomer_WDAD PF04053.14 KIY43906.1 - 0.042 12.9 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region PD40 PF07676.12 KIY43906.1 - 0.11 12.5 1.3 3.7 7.6 0.7 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KIY43906.1 - 0.25 9.3 0.0 0.39 8.6 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Det1 PF09737.9 KIY43906.1 - 0.29 10.2 0.0 0.45 9.5 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Glyco_transf_18 PF15024.6 KIY43907.1 - 3.1e-14 52.5 0.0 5.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 Arginase PF00491.21 KIY43908.1 - 1e-65 222.0 0.0 1.2e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family Pro_isomerase PF00160.21 KIY43909.1 - 2.1e-47 161.3 0.0 2.4e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.20 KIY43910.1 - 1.1e-125 419.5 0.0 1.3e-125 419.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY43910.1 - 1.3e-13 50.8 0.1 3.6e-11 42.8 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 KIY43910.1 - 0.00017 21.2 0.0 0.0048 16.5 0.1 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KIY43910.1 - 0.00038 20.7 0.0 0.51 10.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIY43910.1 - 0.011 15.1 0.1 2.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.11 KIY43910.1 - 0.018 14.4 0.1 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KIY43910.1 - 0.055 13.2 0.0 0.72 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIY43910.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRP1_N PF06424.12 KIY43910.1 - 0.14 12.5 2.4 0.34 11.3 1.1 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Sugar_tr PF00083.24 KIY43911.1 - 3.6e-117 392.0 23.0 4.1e-117 391.8 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY43911.1 - 6.8e-23 81.2 36.4 1.5e-19 70.2 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Whi5 PF08528.11 KIY43912.1 - 3e-05 23.5 0.0 5.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Whi5 like adh_short PF00106.25 KIY43914.1 - 1.4e-20 73.6 0.0 1.9e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY43914.1 - 3e-17 63.0 0.0 4.1e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GATA PF00320.27 KIY43915.1 - 5.3e-15 54.7 3.0 9.4e-15 53.9 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger PapD_N PF00345.20 KIY43915.1 - 0.004 17.1 0.9 0.011 15.6 0.9 1.7 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain FAM76 PF16046.5 KIY43915.1 - 0.0042 16.5 5.6 0.0094 15.3 5.6 1.6 1 0 0 1 1 1 1 FAM76 protein RRM_1 PF00076.22 KIY43917.1 - 1.3e-17 63.3 0.0 1e-10 41.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.23 KIY43918.1 - 7.6e-05 22.7 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY43918.1 - 0.016 14.6 0.0 4.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43918.1 - 0.067 12.5 0.0 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Imm8 PF15586.6 KIY43918.1 - 0.072 13.1 0.0 0.78 9.8 0.1 2.0 2 0 0 2 2 2 0 Immunity protein 8 SIR2 PF02146.17 KIY43920.1 - 1.3e-30 106.6 0.0 3.8e-23 82.3 0.0 2.4 2 1 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KIY43920.1 - 0.022 14.5 0.1 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PLATZ PF04640.14 KIY43921.1 - 0.037 14.6 2.3 0.086 13.5 1.4 2.1 2 0 0 2 2 2 0 PLATZ transcription factor zf-MYND PF01753.18 KIY43921.1 - 0.12 12.4 0.8 0.32 11.1 0.8 1.6 1 0 0 1 1 1 0 MYND finger adh_short PF00106.25 KIY43922.1 - 2.1e-18 66.5 0.0 2.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY43922.1 - 4.5e-17 62.4 0.0 5.3e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Metallophos PF00149.28 KIY43923.1 - 7.2e-36 124.6 0.6 1e-35 124.1 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY43923.1 - 0.0011 19.4 0.2 0.0021 18.5 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KIY43923.1 - 0.028 14.0 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain cwf21 PF08312.12 KIY43923.1 - 2.2 8.5 4.1 0.68 10.1 1.2 1.7 2 0 0 2 2 2 0 cwf21 domain Cpn60_TCP1 PF00118.24 KIY43924.1 - 1.2e-152 509.0 2.3 1.4e-152 508.8 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo PF00385.24 KIY43925.1 - 3.8e-11 42.7 0.9 6.3e-11 42.0 0.9 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1729 PF08354.10 KIY43927.1 - 5.9e-142 472.7 0.0 9.9e-142 472.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Fas_alpha_ACP PF18325.1 KIY43927.1 - 2.6e-73 245.7 0.0 7.7e-73 244.2 0.0 1.9 2 0 0 2 2 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KIY43927.1 - 9.3e-73 244.2 0.0 3.1e-72 242.5 0.0 2.0 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 KIY43927.1 - 3e-71 240.5 0.2 1.6e-69 234.9 0.0 3.2 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KIY43927.1 - 1.7e-39 135.0 0.0 3.7e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KIY43927.1 - 3.7e-27 95.6 0.7 9.5e-27 94.3 0.1 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KIY43927.1 - 1.6e-25 89.0 0.0 4.2e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain ketoacyl-synt PF00109.26 KIY43927.1 - 6.4e-21 75.1 0.5 1.3e-20 74.0 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KIY43927.1 - 1.6e-14 53.9 0.0 4.2e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 KIY43927.1 - 2.9e-13 49.9 0.0 7.1e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 KIY43927.1 - 5.9e-10 38.9 0.0 2.6e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY43927.1 - 3.6e-06 26.7 0.0 0.00029 20.5 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY43927.1 - 0.025 14.5 0.4 0.21 11.5 0.0 2.5 2 0 0 2 2 2 0 KR domain Asp PF00026.23 KIY43928.1 - 9.6e-46 156.6 15.9 2e-45 155.6 15.9 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY43928.1 - 0.00047 20.4 1.4 0.0071 16.6 0.7 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIY43928.1 - 0.019 14.7 0.5 1 9.1 0.5 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KIY43928.1 - 0.09 13.4 2.0 2.8 8.7 0.2 2.6 2 0 0 2 2 2 0 Aspartyl protease Asp PF00026.23 KIY43929.1 - 1.4e-44 152.8 5.2 4.9e-44 151.0 5.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY43929.1 - 5.8e-08 33.2 0.4 4.7e-05 23.7 0.0 3.4 2 1 2 4 4 4 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIY43929.1 - 0.012 15.4 0.1 0.13 12.1 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KIY43929.1 - 0.13 12.9 1.0 33 5.2 0.2 3.2 2 1 0 2 2 2 0 Aspartyl protease Prp18 PF02840.15 KIY43933.1 - 2.1e-60 202.9 0.1 3.9e-60 202.0 0.1 1.4 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 KIY43933.1 - 1.3e-11 43.8 5.9 1.3e-11 43.8 5.9 2.6 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like tRNA_U5-meth_tr PF05958.11 KIY43934.1 - 9e-19 67.7 0.0 4.3e-18 65.4 0.0 1.9 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KIY43934.1 - 8.8e-09 35.1 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KIY43934.1 - 3e-07 30.3 0.0 6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KIY43934.1 - 4.9e-05 23.9 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY43934.1 - 0.00058 20.4 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY43934.1 - 0.00086 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY43934.1 - 0.0041 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltrans_SAM PF10672.9 KIY43934.1 - 0.0086 15.3 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase PrmA PF06325.13 KIY43934.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 KIY43934.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Met_10 PF02475.16 KIY43934.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein NIF PF03031.18 KIY43935.1 - 9.2e-11 41.7 0.8 2.4e-09 37.1 0.1 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Pkinase PF00069.25 KIY43936.1 - 9.3e-47 159.6 0.0 6.4e-34 117.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY43936.1 - 4.2e-33 114.7 0.0 9.9e-29 100.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY43936.1 - 0.00011 21.1 0.0 0.00017 20.5 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY43936.1 - 0.003 17.5 0.2 0.0062 16.5 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY43936.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KIY43936.1 - 0.029 13.7 0.0 8.4 5.6 0.0 2.6 3 0 0 3 3 3 0 Kinase-like RIO1 PF01163.22 KIY43936.1 - 0.061 12.9 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family DUF1325 PF07039.11 KIY43937.1 - 2.2e-37 128.1 0.1 3e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Msg2_C PF12373.8 KIY43937.1 - 0.05 13.0 0.5 0.11 12.0 0.5 1.5 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Tudor_3 PF18115.1 KIY43937.1 - 0.069 13.0 0.9 0.41 10.5 0.2 2.4 2 1 0 2 2 2 0 DNA repair protein Crb2 Tudor domain DUF21 PF01595.20 KIY43938.1 - 1.1e-29 103.3 0.0 1.7e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIY43938.1 - 2.3e-05 24.8 0.6 0.66 10.5 0.1 3.5 3 0 0 3 3 3 2 CBS domain TFIIS_C PF01096.18 KIY43939.1 - 8e-21 73.6 4.7 8e-21 73.6 4.7 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIY43939.1 - 2e-09 37.1 0.6 2e-09 37.1 0.6 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.12 KIY43939.1 - 8.9e-05 22.4 6.5 0.17 11.9 0.2 3.4 3 0 0 3 3 3 2 PhnA Zinc-Ribbon DUF3716 PF12511.8 KIY43939.1 - 0.017 15.2 8.8 0.055 13.5 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Zn_ribbon_recom PF13408.6 KIY43939.1 - 0.19 12.3 4.1 0.64 10.6 0.2 2.6 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain Tnp_zf-ribbon_2 PF13842.6 KIY43939.1 - 0.36 11.7 9.6 5.4 7.9 0.1 3.5 4 0 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon zinc_ribbon_4 PF13717.6 KIY43939.1 - 0.59 10.1 8.9 2.6 8.0 0.4 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KIY43939.1 - 1.2 9.2 9.8 0.56 10.2 0.2 2.9 2 1 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KIY43939.1 - 2.7 8.2 10.7 12 6.2 0.5 4.1 4 1 1 5 5 5 0 Zinc ribbon domain PHD PF00628.29 KIY43939.1 - 2.8 7.9 13.8 2.7 8.0 2.5 3.2 2 2 0 2 2 2 0 PHD-finger IBR PF01485.21 KIY43939.1 - 3.3 8.0 12.0 0.58 10.4 0.4 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_15 PF17032.5 KIY43939.1 - 3.9 8.3 11.8 60 4.5 8.9 2.8 1 1 1 2 2 2 0 zinc-ribbon family zf-3CxxC PF13695.6 KIY43939.1 - 6.4 7.3 11.4 3.1 8.3 2.9 2.2 1 1 1 2 2 2 0 Zinc-binding domain Cation_ATPase_C PF00689.21 KIY43940.1 - 3.4e-48 163.8 4.4 3.4e-48 163.8 4.4 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KIY43940.1 - 2e-36 125.2 0.1 2e-36 125.2 0.1 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KIY43940.1 - 7.9e-21 74.0 0.0 1.5e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIY43940.1 - 4.3e-16 59.8 0.2 1.2e-15 58.3 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIY43940.1 - 1.9e-07 30.6 0.1 1.2e-06 28.2 0.1 2.3 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY43940.1 - 0.00024 20.9 1.0 0.019 14.7 0.4 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.7 KIY43941.1 - 1.3e-09 39.0 4.7 2e-09 38.4 4.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY43941.1 - 0.0085 15.8 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Bud13 PF09736.9 KIY43942.1 - 7.2e-53 178.9 6.5 7.2e-53 178.9 6.5 1.8 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex ADH_N_2 PF16884.5 KIY43944.1 - 5.2e-28 97.1 0.0 9.2e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KIY43944.1 - 1.2e-16 60.8 0.1 1.9e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY43944.1 - 3.3e-05 24.9 0.0 5.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY43944.1 - 0.0015 18.4 0.5 0.0027 17.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 KIY43944.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus LRR_4 PF12799.7 KIY43946.1 - 1.7e-34 117.3 31.5 7.3e-08 32.6 1.7 7.2 4 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY43946.1 - 6.3e-24 83.5 30.2 1.8e-10 40.4 4.3 6.3 3 1 4 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 KIY43946.1 - 1.5e-20 73.5 13.7 6.8e-10 38.7 0.1 3.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KIY43946.1 - 1.5e-07 31.0 33.8 14 6.7 0.5 10.7 10 1 1 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 KIY43946.1 - 0.023 14.7 25.4 7.9 6.8 0.4 9.6 11 1 1 12 12 12 0 Leucine Rich repeat tRNA-synt_1g PF09334.11 KIY43947.1 - 4.3e-131 437.3 0.0 5.5e-131 436.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KIY43947.1 - 1.7e-08 34.5 1.3 1.7e-08 34.5 1.3 1.7 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 KIY43947.1 - 0.00012 20.5 0.0 0.0011 17.3 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) UPF0547 PF10571.9 KIY43947.1 - 0.19 11.9 0.7 0.55 10.4 0.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DZR PF12773.7 KIY43947.1 - 3.9 7.6 6.9 12 6.0 6.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF4078 PF13300.6 KIY43948.1 - 3.1e-17 62.7 4.3 3.1e-17 62.7 4.3 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4078) Fez1 PF06818.15 KIY43949.1 - 0.058 13.8 7.1 0.076 13.5 7.1 1.2 1 0 0 1 1 1 0 Fez1 FapA PF03961.13 KIY43949.1 - 0.078 11.6 4.1 0.099 11.2 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5320 PF17253.2 KIY43949.1 - 0.46 11.6 1.8 0.86 10.7 1.8 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5320) Spectrin PF00435.21 KIY43949.1 - 0.72 10.4 8.6 2.2 8.8 8.0 2.0 1 1 1 2 2 2 0 Spectrin repeat DUF2605 PF10792.9 KIY43949.1 - 0.79 9.7 5.1 1.5 8.8 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) FOXP-CC PF16159.5 KIY43949.1 - 0.84 10.3 4.0 2 9.1 4.0 1.6 1 0 0 1 1 1 0 FOXP coiled-coil domain FAM76 PF16046.5 KIY43949.1 - 1.7 7.9 8.0 2.2 7.5 8.0 1.1 1 0 0 1 1 1 0 FAM76 protein SlyX PF04102.12 KIY43949.1 - 4 8.1 10.2 13 6.4 0.0 2.8 2 1 1 3 3 3 0 SlyX DUF3734 PF12536.8 KIY43949.1 - 4.1 7.8 7.8 2 8.8 1.9 2.6 2 1 1 3 3 3 0 Patatin phospholipase Voldacs PF03517.13 KIY43950.1 - 5.8e-25 88.0 0.6 1.2e-24 87.0 0.1 1.7 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Aminotran_4 PF01063.19 KIY43952.1 - 4e-26 92.3 0.0 5.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV TauD PF02668.16 KIY43953.1 - 1.5e-39 136.4 0.0 2.1e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KIY43953.1 - 1.5e-09 38.4 0.2 2.8e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KIY43953.1 - 0.0045 16.1 0.0 0.034 13.3 0.0 1.9 2 0 0 2 2 2 1 CsiD Aconitase PF00330.20 KIY43954.1 - 3.9e-111 372.3 0.1 4.8e-110 368.7 0.1 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIY43954.1 - 2.4e-21 76.4 0.1 5.8e-21 75.2 0.1 1.7 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KIY43954.1 - 0.02 13.6 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Na_Ca_ex PF01699.24 KIY43955.1 - 3.4e-44 150.5 53.0 9.9e-28 97.0 14.7 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YchF-GTPase_C PF06071.13 KIY43956.1 - 7.1e-35 119.1 0.0 1.8e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KIY43956.1 - 1.3e-19 70.4 0.0 4.8e-19 68.5 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY43956.1 - 4e-08 32.9 0.0 8.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KIY43956.1 - 0.01 14.8 1.2 0.023 13.7 0.0 2.0 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pro_isomerase PF00160.21 KIY43957.1 - 2.7e-43 148.0 0.0 2.9e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 KIY43958.1 - 1.8e-45 154.5 0.0 2e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY43958.1 - 1.6e-18 67.1 0.0 2e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIY43958.1 - 5.4e-06 26.4 0.0 0.007 16.3 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Arf PF00025.21 KIY43958.1 - 1.1e-05 24.9 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY43958.1 - 0.00017 21.2 0.0 0.00047 19.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY43958.1 - 0.00086 19.4 0.1 0.0012 18.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF5040 PF16443.5 KIY43958.1 - 0.0051 16.2 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5040) AAA_33 PF13671.6 KIY43958.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KIY43958.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KIY43958.1 - 0.072 13.4 0.1 0.44 10.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain TPP_enzyme_M PF00205.22 KIY43958.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain AAA_16 PF13191.6 KIY43958.1 - 0.092 13.1 0.7 0.45 10.9 0.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KIY43958.1 - 0.17 11.9 0.0 0.48 10.5 0.0 1.7 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain DUF4965 PF16335.5 KIY43959.1 - 4.6e-63 212.0 0.3 7.7e-63 211.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KIY43959.1 - 5.3e-55 186.7 2.0 8.2e-55 186.0 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KIY43959.1 - 1.2e-37 129.9 0.3 1.2e-37 129.9 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIY43959.1 - 2.3e-06 27.1 0.0 6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) GATA PF00320.27 KIY43960.1 - 6.7e-14 51.2 4.1 1.5e-13 50.1 4.1 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 KIY43960.1 - 0.00019 21.7 0.0 0.00051 20.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KIY43960.1 - 0.0065 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KIY43960.1 - 0.0084 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KIY43960.1 - 0.016 15.2 0.0 0.06 13.3 0.0 1.9 2 0 0 2 2 2 0 PAS fold Ank_5 PF13857.6 KIY43961.1 - 2.4e-11 43.6 0.0 8.5e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIY43961.1 - 1.6e-10 41.3 0.0 2.2e-08 34.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KIY43961.1 - 6.5e-08 32.7 0.0 0.00012 22.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KIY43961.1 - 3.8e-07 29.9 0.0 5.5e-06 26.3 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KIY43961.1 - 5.4e-07 30.1 0.0 1.6e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) TipAS PF07739.13 KIY43961.1 - 0.068 13.7 0.4 0.12 12.9 0.4 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Syntaxin-5_N PF11416.8 KIY43961.1 - 0.23 10.8 0.1 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 Syntaxin-5 N-terminal, Sly1p-binding domain Citrate_synt PF00285.21 KIY43963.1 - 3e-116 388.4 0.0 3.6e-116 388.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PH PF00169.29 KIY43964.1 - 2.4e-06 28.0 0.0 0.001 19.6 0.0 3.2 3 0 0 3 3 3 2 PH domain PH_9 PF15410.6 KIY43964.1 - 0.00074 19.9 0.1 0.0023 18.3 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Tetraspanin PF00335.20 KIY43965.1 - 3.6e-10 39.9 10.9 5.2e-10 39.4 10.9 1.2 1 0 0 1 1 1 1 Tetraspanin family NDUF_B8 PF05821.11 KIY43965.1 - 0.017 15.0 0.1 0.078 12.8 0.1 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) GalKase_gal_bdg PF10509.9 KIY43966.1 - 1.4e-21 75.8 0.0 3.2e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KIY43966.1 - 1.3e-14 54.3 0.1 4.4e-14 52.6 0.1 1.9 1 1 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KIY43966.1 - 1.2e-11 44.7 2.4 2.5e-11 43.6 2.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Aldose_epim PF01263.20 KIY43967.1 - 1.4e-23 83.6 0.0 7.2e-22 78.1 0.0 3.0 1 1 0 1 1 1 1 Aldose 1-epimerase Drf_GBD PF06371.13 KIY43968.1 - 1.3e-18 67.2 0.0 6.5e-14 51.9 0.1 2.7 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain PAS_3 PF08447.12 KIY43970.1 - 0.2 12.0 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 PAS fold ACBP PF00887.19 KIY43971.1 - 3.8e-30 104.0 0.5 5.6e-30 103.4 0.5 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.29 KIY43972.1 - 1.5e-32 112.2 0.2 3.6e-17 62.8 0.3 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KIY43972.1 - 8.4e-13 48.7 6.9 1e-05 25.9 3.2 3.5 2 2 1 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 KIY43972.1 - 1.5e-08 34.7 0.8 8.7e-05 22.6 0.1 3.5 2 2 1 3 3 3 2 PH domain PH_8 PF15409.6 KIY43972.1 - 1.9e-06 28.1 0.6 0.00019 21.7 0.2 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH_4 PF15404.6 KIY43972.1 - 0.0039 17.0 0.2 0.043 13.6 0.1 2.3 1 1 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KIY43972.1 - 0.19 11.8 2.8 1.4 9.0 0.0 2.8 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Fungal_trans_2 PF11951.8 KIY43973.1 - 2.8e-21 75.8 0.0 3.3e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KIY43974.1 - 6.8e-33 114.0 0.5 6.8e-33 114.0 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY43974.1 - 0.0096 16.0 8.5 0.018 15.2 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_N PF00752.17 KIY43975.1 - 6.3e-31 106.9 0.0 1.3e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIY43975.1 - 1.4e-27 95.8 0.0 3.9e-27 94.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KIY43975.1 - 0.00081 18.9 0.0 0.0018 17.8 0.0 1.6 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KIY43975.1 - 0.04 14.5 0.1 0.21 12.2 0.0 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold FCP1_C PF09309.10 KIY43975.1 - 0.073 12.9 12.2 0.24 11.2 12.2 1.9 1 0 0 1 1 1 0 FCP1, C-terminal Trehalase PF01204.18 KIY43976.1 - 3.5e-166 554.0 0.1 4.3e-166 553.7 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KIY43976.1 - 1.3e-13 50.4 0.1 2.4e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain CtaG_Cox11 PF04442.14 KIY43977.1 - 3.7e-59 199.1 0.1 5.1e-59 198.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 UCR_Fe-S_N PF10399.9 KIY43977.1 - 0.15 11.4 4.0 0.062 12.7 1.4 1.7 1 1 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Methyltransf_25 PF13649.6 KIY43978.1 - 1.4e-13 51.4 0.0 2.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY43978.1 - 2.5e-08 33.6 0.0 3.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIY43978.1 - 5e-08 32.9 0.0 9.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY43978.1 - 8.2e-08 32.8 0.0 2.4e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KIY43978.1 - 0.00019 21.6 0.0 0.001 19.2 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KIY43978.1 - 0.00021 21.2 0.0 0.00051 19.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY43978.1 - 0.0003 21.5 0.0 0.00064 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY43978.1 - 0.001 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KIY43978.1 - 0.0059 17.6 0.0 0.011 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIY43978.1 - 0.018 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_15 PF09445.10 KIY43978.1 - 0.059 12.9 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 KIY43978.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KIY43978.1 - 0.2 11.6 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Rep_1B PF17873.1 KIY43978.1 - 0.5 10.3 1.5 0.57 10.1 0.0 1.8 2 0 0 2 2 2 0 Replicase polyprotein 1ab HD-ZIP_N PF04618.12 KIY43978.1 - 0.83 10.2 2.7 0.84 10.2 0.4 2.3 2 1 0 2 2 2 0 HD-ZIP protein N terminus Gtr1_RagA PF04670.12 KIY43979.1 - 4.5e-47 160.3 0.0 5.5e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KIY43979.1 - 0.0051 16.3 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY43979.1 - 0.006 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase HMG_box PF00505.19 KIY43981.1 - 0.023 15.1 1.4 0.05 14.0 1.4 1.6 1 1 0 1 1 1 0 HMG (high mobility group) box Xpo1 PF08389.12 KIY43983.1 - 3.7e-19 69.3 0.0 2.5e-17 63.3 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KIY43983.1 - 0.012 15.5 3.7 0.013 15.4 0.1 3.0 5 0 0 5 5 5 0 Importin-beta N-terminal domain TetR_C_30 PF17939.1 KIY43983.1 - 0.019 15.2 0.0 0.093 13.0 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_11 PF08241.12 KIY43983.1 - 0.13 12.9 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GATA PF00320.27 KIY43985.1 - 4.9e-20 70.8 22.8 1.3e-11 43.9 6.0 2.4 2 0 0 2 2 2 2 GATA zinc finger NMD3 PF04981.13 KIY43985.1 - 0.86 9.0 4.1 12 5.3 0.1 2.1 2 0 0 2 2 2 0 NMD3 family DnaJ PF00226.31 KIY43986.1 - 2.7e-17 62.7 0.4 6.7e-17 61.4 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain Jak1_Phl PF17887.1 KIY43986.1 - 0.26 11.2 4.8 0.51 10.3 4.8 1.4 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Peptidase_M24 PF00557.24 KIY43987.1 - 2.9e-18 66.3 0.5 3.9e-18 65.9 0.5 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pcc1 PF09341.10 KIY43988.1 - 6.5e-22 77.5 0.7 7.4e-22 77.3 0.7 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF3256 PF11644.8 KIY43988.1 - 0.05 13.1 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Actin PF00022.19 KIY43989.1 - 9.4e-88 294.5 0.0 3.4e-86 289.4 0.0 2.0 1 1 0 1 1 1 1 Actin CFEM PF05730.11 KIY43990.1 - 1.4e-09 37.9 7.1 2.6e-09 37.0 7.1 1.4 1 0 0 1 1 1 1 CFEM domain Ribosomal_L10 PF00466.20 KIY43991.1 - 5.6e-24 84.2 0.5 3e-23 81.8 0.0 2.2 2 1 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KIY43991.1 - 9.2e-22 77.4 9.2 9.2e-22 77.4 9.2 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 KIY43991.1 - 1.8e-21 75.9 0.0 3e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P F-box-like PF12937.7 KIY43992.1 - 2.8e-09 36.7 0.3 6.5e-09 35.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY43992.1 - 3.9e-07 29.8 0.3 8.4e-07 28.7 0.3 1.6 1 0 0 1 1 1 1 F-box domain Cullin PF00888.22 KIY43994.1 - 6.7e-187 622.9 0.8 7.9e-187 622.6 0.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIY43994.1 - 5.8e-21 74.3 0.1 1.4e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain LIFR_D2 PF17971.1 KIY43994.1 - 0.17 12.1 0.3 0.56 10.4 0.1 1.9 2 0 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain XLF PF09302.11 KIY43995.1 - 5e-05 23.5 1.3 0.00025 21.3 1.3 1.9 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Arrestin_N PF00339.29 KIY43996.1 - 0.00022 21.3 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain TOM13 PF08219.11 KIY43997.1 - 2.2e-14 53.2 0.5 6.1e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Outer membrane protein TOM13 KTI12 PF08433.10 KIY43998.1 - 3.4e-81 272.7 0.0 3.9e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KIY43998.1 - 7.9e-12 45.5 0.0 1.3e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KIY43998.1 - 0.046 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KIY43998.1 - 0.066 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pam16 PF03656.13 KIY43999.1 - 1.4e-19 70.3 4.4 1.7e-12 47.5 2.3 2.5 1 1 1 2 2 2 2 Pam16 DnaJ PF00226.31 KIY43999.1 - 0.072 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 DnaJ domain DUF4070 PF13282.6 KIY43999.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4070) AIM3 PF17096.5 KIY43999.1 - 7.6 7.6 11.6 1.2e+02 3.7 11.6 2.3 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 RPA43_OB PF17875.1 KIY44000.1 - 1.1e-23 84.2 6.9 4.1e-23 82.3 0.0 3.0 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KIY44000.1 - 1.1e-06 28.9 0.0 2.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 FAM176 PF14851.6 KIY44000.1 - 0.011 15.4 0.2 0.024 14.3 0.2 1.5 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 KIY44000.1 - 0.12 10.4 10.2 0.15 10.1 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cellulase PF00150.18 KIY44001.1 - 1.9e-49 168.6 0.1 2.2e-49 168.4 0.1 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SARAF PF06682.12 KIY44002.1 - 5e-43 148.0 0.1 5.4e-43 147.9 0.1 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DRIM PF07539.12 KIY44004.1 - 1.1e-150 503.0 1.0 1.1e-150 503.0 1.0 3.8 4 1 0 4 4 4 1 Down-regulated in metastasis RNase_T PF00929.24 KIY44004.1 - 0.023 15.2 0.9 2 9.0 0.0 3.2 3 0 0 3 3 3 0 Exonuclease Condensin2nSMC PF12422.8 KIY44004.1 - 0.064 13.4 2.0 7.1 6.8 0.0 4.7 4 1 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit HEAT_2 PF13646.6 KIY44004.1 - 0.18 12.2 2.9 12 6.3 0.1 5.4 6 0 0 6 6 6 0 HEAT repeats OPT PF03169.15 KIY44005.1 - 6.9e-134 447.8 25.9 9.7e-134 447.3 25.9 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 KIY44005.1 - 7.4e-05 22.7 3.6 0.27 11.2 0.2 4.0 3 0 0 3 3 3 2 Bacteriophage P21 holin S ADH_N PF08240.12 KIY44006.1 - 7.9e-30 102.9 1.8 1.3e-29 102.2 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY44006.1 - 8.2e-27 93.7 0.6 1.3e-26 93.1 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY44006.1 - 0.018 16.1 0.4 0.46 11.5 0.4 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 KIY44006.1 - 0.069 13.3 0.2 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SART-1 PF03343.13 KIY44009.1 - 9e-63 212.8 28.1 1.1e-62 212.6 28.1 1.0 1 0 0 1 1 1 1 SART-1 family Auxin_canalis PF05703.11 KIY44009.1 - 0.55 10.1 3.4 0.8 9.6 3.4 1.2 1 0 0 1 1 1 0 Auxin canalisation DUF515 PF04415.12 KIY44009.1 - 1.1 7.6 5.8 1.9 6.8 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) NLBH PF05211.12 KIY44011.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) zf-CCCH PF00642.24 KIY44012.1 - 0.011 15.6 1.9 0.027 14.4 1.9 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY44012.1 - 0.44 10.7 5.4 2.2 8.5 4.1 2.5 2 1 0 2 2 2 0 Zinc finger domain Fez1 PF06818.15 KIY44015.1 - 4.6e-05 24.0 23.1 0.00072 20.1 1.3 3.0 1 1 2 3 3 3 2 Fez1 Spc7 PF08317.11 KIY44015.1 - 0.0002 20.4 28.7 0.0081 15.1 4.6 2.9 2 1 0 2 2 2 2 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 KIY44015.1 - 0.001 18.7 0.2 0.001 18.7 0.2 2.9 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4201 PF13870.6 KIY44015.1 - 0.0011 18.8 13.7 0.099 12.4 1.2 3.4 3 1 0 3 3 3 2 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.7 KIY44015.1 - 0.0032 17.6 25.4 1 9.5 3.5 3.6 2 1 1 3 3 3 2 Tropomyosin like BRE1 PF08647.11 KIY44015.1 - 0.0037 17.3 2.2 0.0037 17.3 2.2 3.4 3 1 0 3 3 3 1 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 KIY44015.1 - 0.012 15.7 19.6 0.3 11.2 4.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KIY44015.1 - 0.012 15.8 23.6 0.75 9.9 3.3 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 KIY44015.1 - 0.015 15.4 3.3 0.015 15.4 3.3 3.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec20 PF03908.13 KIY44015.1 - 0.017 15.0 1.3 0.017 15.0 1.3 2.9 2 1 0 2 2 2 0 Sec20 Csm1_N PF18504.1 KIY44015.1 - 0.023 15.0 2.3 0.023 15.0 2.3 5.0 2 2 3 5 5 4 0 Csm1 N-terminal domain KASH_CCD PF14662.6 KIY44015.1 - 0.031 14.1 24.3 0.75 9.6 9.8 3.9 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4200 PF13863.6 KIY44015.1 - 0.066 13.6 22.4 1.5 9.3 8.4 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF2163 PF09931.9 KIY44015.1 - 0.081 13.1 3.3 0.065 13.4 1.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2163) FlaC_arch PF05377.11 KIY44015.1 - 0.11 12.9 12.8 3.6 8.0 0.1 4.1 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KIY44015.1 - 0.11 12.7 32.2 0.4 10.9 4.2 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Tup_N PF08581.10 KIY44015.1 - 0.12 12.7 0.4 0.12 12.7 0.4 3.0 3 1 0 3 3 2 0 Tup N-terminal YabA PF06156.13 KIY44015.1 - 0.15 12.7 15.1 0.24 12.1 1.9 3.3 2 1 1 3 3 3 0 Initiation control protein YabA DUF641 PF04859.12 KIY44015.1 - 0.15 12.4 20.1 1.5 9.2 1.2 3.7 2 2 0 2 2 2 0 Plant protein of unknown function (DUF641) HrpB7 PF09486.10 KIY44015.1 - 0.18 12.2 34.2 0.27 11.6 3.1 4.2 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) TMF_TATA_bd PF12325.8 KIY44015.1 - 0.29 11.3 23.7 3 8.1 5.0 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 KIY44015.1 - 0.3 11.1 27.2 0.049 13.7 4.5 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Wtap PF17098.5 KIY44015.1 - 0.4 10.6 17.1 0.4 10.6 1.1 2.3 2 0 0 2 2 2 0 WTAP/Mum2p family Atg14 PF10186.9 KIY44015.1 - 0.61 9.1 20.4 0.64 9.1 2.9 2.8 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MscS_porin PF12795.7 KIY44015.1 - 0.64 9.5 41.9 0.024 14.2 10.5 2.8 2 2 0 2 2 2 0 Mechanosensitive ion channel porin domain SlyX PF04102.12 KIY44015.1 - 0.93 10.2 27.9 0.78 10.4 5.8 4.5 2 2 1 4 4 4 0 SlyX CC2-LZ PF16516.5 KIY44015.1 - 1 9.8 20.9 0.85 10.0 1.8 3.9 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HMMR_N PF15905.5 KIY44015.1 - 1.2 8.5 26.3 0.86 9.0 5.1 2.6 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF724 PF05266.14 KIY44015.1 - 1.2 8.9 20.6 0.2 11.4 2.0 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF724) Tropomyosin PF00261.20 KIY44015.1 - 1.3 8.4 25.6 0.33 10.3 6.2 2.3 2 0 0 2 2 2 0 Tropomyosin BLOC1_2 PF10046.9 KIY44015.1 - 1.9 8.8 15.3 1.2 9.5 3.4 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliJ PF02050.16 KIY44015.1 - 2 8.6 31.2 0.84 9.9 1.0 3.5 2 2 1 3 3 3 0 Flagellar FliJ protein Prefoldin PF02996.17 KIY44015.1 - 2.2 8.2 23.5 2.3 8.2 0.2 4.6 3 1 0 4 4 4 0 Prefoldin subunit FAM76 PF16046.5 KIY44015.1 - 2.2 7.5 18.5 2.9 7.2 8.4 2.7 2 1 0 2 2 2 0 FAM76 protein Med9 PF07544.13 KIY44015.1 - 2.3 8.4 15.4 0.87 9.7 0.2 4.4 2 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 RGS_DHEX PF18148.1 KIY44015.1 - 3.4 7.8 6.6 0.46 10.6 0.9 2.4 3 1 0 3 3 2 0 Regulator of G-protein signalling DHEX domain Sec2p PF06428.11 KIY44015.1 - 3.5 7.7 23.2 3.7 7.6 0.0 4.7 2 2 3 5 5 5 0 GDP/GTP exchange factor Sec2p DUF1003 PF06210.11 KIY44015.1 - 3.7 7.7 12.8 0.06 13.4 3.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) HAP1_N PF04849.13 KIY44015.1 - 4.3 6.4 24.7 3.5 6.7 9.6 3.1 2 1 1 3 3 3 0 HAP1 N-terminal conserved region Uso1_p115_C PF04871.13 KIY44015.1 - 4.4 7.7 31.1 0.17 12.3 5.9 3.3 2 1 1 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TolA_bind_tri PF16331.5 KIY44015.1 - 4.8 7.3 20.7 0.2 11.8 5.4 3.9 3 3 0 3 3 2 0 TolA binding protein trimerisation AAA_13 PF13166.6 KIY44015.1 - 4.8 5.7 20.8 3.2 6.3 1.8 2.4 2 1 0 2 2 2 0 AAA domain DivIC PF04977.15 KIY44015.1 - 6.2 6.7 30.6 1.2 8.9 1.3 5.7 2 2 4 6 6 6 0 Septum formation initiator MAD PF05557.13 KIY44015.1 - 6.4 5.0 25.2 3.8 5.8 15.1 2.3 2 0 0 2 2 2 0 Mitotic checkpoint protein TMF_DNA_bd PF12329.8 KIY44015.1 - 7.2 6.7 24.2 6.6 6.8 0.9 4.5 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding SYCE1 PF15233.6 KIY44015.1 - 7.8 6.5 21.4 0.14 12.2 3.4 2.5 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 SART-1 PF03343.13 KIY44016.1 - 2.3e-160 535.2 59.6 2.3e-160 535.2 59.6 1.9 2 0 0 2 2 2 1 SART-1 family Tube PF17212.3 KIY44016.1 - 1.4 9.0 5.8 1 9.4 0.1 3.0 3 0 0 3 3 3 0 Tail tubular protein Arg_tRNA_synt_N PF03485.16 KIY44016.1 - 2.2 8.9 4.4 17 6.1 0.3 3.5 3 1 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain CHORD PF04968.12 KIY44017.1 - 1 10.1 6.6 3.7 8.3 5.9 2.1 1 1 0 1 1 1 0 CHORD IMUP PF15761.5 KIY44017.1 - 1.4 9.7 12.2 3.8 8.3 3.1 2.1 1 1 1 2 2 2 0 Immortalisation up-regulated protein Acyl-CoA_dh_1 PF00441.24 KIY44018.1 - 5.4e-30 104.6 2.1 7.9e-30 104.0 2.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KIY44018.1 - 5.9e-18 64.8 0.0 1.5e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KIY44018.1 - 4e-17 62.2 0.2 7.1e-17 61.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KIY44018.1 - 3e-15 56.9 0.0 8.7e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIY44018.1 - 4.5e-06 27.0 1.0 8.6e-06 26.1 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mago_nashi PF02792.14 KIY44019.1 - 6.4e-76 253.3 0.3 7.1e-76 253.1 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Peptidase_C74 PF12387.8 KIY44019.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Fungal_trans PF04082.18 KIY44020.1 - 3.6e-09 36.0 0.2 6.8e-09 35.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain COX6B PF02297.17 KIY44021.1 - 3e-20 72.2 1.0 4e-20 71.8 1.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DAP3 PF10236.9 KIY44021.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Pet191_N PF10203.9 KIY44021.1 - 0.076 13.3 0.8 0.3 11.4 0.9 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NAD_binding_10 PF13460.6 KIY44022.1 - 7.2e-11 42.3 1.2 1.1e-10 41.7 1.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY44022.1 - 5e-09 36.1 0.4 7.6e-09 35.5 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIY44022.1 - 1.8e-07 30.9 0.2 0.00075 19.0 0.2 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY44022.1 - 2.2e-06 26.9 0.1 3.1e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY44022.1 - 4.2e-06 26.1 0.0 6.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KIY44022.1 - 0.0051 16.0 0.1 1.3 8.0 0.1 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Semialdhyde_dh PF01118.24 KIY44022.1 - 0.0071 16.8 0.1 0.017 15.5 0.1 1.8 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIY44022.1 - 0.0099 16.1 0.2 0.021 15.1 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KIY44022.1 - 0.012 16.2 0.2 0.039 14.5 0.1 1.9 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 KIY44022.1 - 0.014 15.4 1.1 0.035 14.1 0.8 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KIY44022.1 - 0.023 15.0 0.3 0.055 13.7 0.3 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Titin_Z PF09042.11 KIY44022.1 - 5.7 7.0 6.8 29 4.7 1.7 2.4 2 0 0 2 2 2 0 Titin Z NAD_binding_10 PF13460.6 KIY44023.1 - 7.4e-06 26.0 0.1 1.4e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KIY44023.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KIY44023.1 - 0.0037 17.5 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 KIY44023.1 - 0.03 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF5040 PF16443.5 KIY44023.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) 3Beta_HSD PF01073.19 KIY44023.1 - 0.2 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Titin_Z PF09042.11 KIY44023.1 - 0.25 11.3 5.9 0.15 12.0 1.0 2.3 2 0 0 2 2 2 0 Titin Z NAD_binding_10 PF13460.6 KIY44024.1 - 1.6e-08 34.6 0.2 2.5e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY44024.1 - 4.2e-08 33.0 0.2 6.5e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIY44024.1 - 3.5e-07 29.9 0.1 0.015 14.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KIY44024.1 - 2.5e-05 23.6 0.1 5.1e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KIY44024.1 - 2.9e-05 23.2 0.1 4.1e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KIY44024.1 - 0.0006 20.1 0.1 0.0012 19.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.17 KIY44024.1 - 0.00065 18.9 0.1 0.19 10.8 0.0 2.5 3 0 0 3 3 3 2 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KIY44024.1 - 0.012 15.8 0.2 0.036 14.3 0.2 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KIY44024.1 - 0.046 14.2 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KIY44024.1 - 0.057 13.4 0.5 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 KIY44024.1 - 0.11 13.1 0.1 0.53 10.9 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 KIY44024.1 - 0.15 11.9 0.2 0.32 10.9 0.1 1.5 2 0 0 2 2 2 0 KR domain Titin_Z PF09042.11 KIY44024.1 - 0.54 10.3 5.5 0.26 11.3 0.5 2.2 2 0 0 2 2 2 0 Titin Z Glyco_hydro_79C PF16862.5 KIY44025.1 - 7e-16 59.0 0.1 1.4e-15 58.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 KIY44025.1 - 0.0042 16.1 0.0 2.1 7.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain Mid2 PF04478.12 KIY44026.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Amnionless PF14828.6 KIY44026.1 - 0.023 13.5 0.1 0.049 12.5 0.0 1.5 2 0 0 2 2 2 0 Amnionless Rick_17kDa_Anti PF05433.15 KIY44026.1 - 0.2 11.6 1.7 0.39 10.6 1.7 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain TAL_FSA PF00923.19 KIY44027.1 - 3.1e-92 309.0 0.0 3.6e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase GSH_synth_ATP PF03917.17 KIY44028.1 - 6.1e-132 439.9 0.0 7e-132 439.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KIY44028.1 - 1.4e-34 118.6 0.0 2.9e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SH3_9 PF14604.6 KIY44029.1 - 0.003 17.4 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Fungal_trans PF04082.18 KIY44030.1 - 2.4e-25 89.1 0.0 4.6e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY44030.1 - 0.00081 19.5 6.9 0.0016 18.5 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 KIY44031.1 - 1.2e-49 169.4 3.1 1.2e-49 169.4 3.1 1.6 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY44031.1 - 3.7e-09 37.1 4.1 1.3e-07 32.0 4.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY44031.1 - 0.08 13.6 3.9 0.51 11.0 0.3 3.4 3 1 0 3 3 3 0 Aspartyl protease DUF3421 PF11901.8 KIY44032.1 - 1e-32 112.5 0.1 1.2e-32 112.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) Cellulase PF00150.18 KIY44033.1 - 8.8e-12 45.0 1.4 2.1e-11 43.8 1.4 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CM2 PF03021.14 KIY44034.1 - 0.2 11.5 0.4 0.28 11.0 0.4 1.3 1 0 0 1 1 1 0 Influenza C virus M2 protein Phage_holin_2_1 PF04971.12 KIY44034.1 - 1.3 9.1 7.4 15 5.7 2.6 2.5 2 0 0 2 2 2 0 Bacteriophage P21 holin S DnaJ_C PF01556.18 KIY44036.1 - 5.5e-28 97.9 0.0 9.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY44036.1 - 2.7e-22 78.7 4.3 4.4e-22 78.0 4.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIY44036.1 - 1.7e-13 50.7 17.0 2.7e-13 50.0 17.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KIY44036.1 - 5.6e-05 23.1 4.6 0.075 13.1 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KIY44036.1 - 0.00019 21.3 7.9 0.018 15.0 0.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 KIY44036.1 - 0.033 13.8 0.6 0.033 13.8 0.6 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Cytochrom_c3_2 PF14537.6 KIY44036.1 - 0.22 12.0 4.7 0.41 11.1 4.7 1.5 1 0 0 1 1 1 0 Cytochrome c3 Lar_restr_allev PF14354.6 KIY44036.1 - 1.7 9.1 12.0 3.8 8.0 0.4 3.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 KIY44036.1 - 2.3 8.3 10.3 14 5.8 10.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon PTP_tm PF18861.1 KIY44037.1 - 0.00075 19.5 0.1 0.0016 18.4 0.1 1.5 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J CE2_N PF17996.1 KIY44037.1 - 0.0009 19.2 1.7 1 9.4 0.0 2.8 2 1 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Tir_receptor_N PF07490.11 KIY44037.1 - 0.0014 18.6 0.6 0.0014 18.6 0.6 1.7 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) N-terminus Amnionless PF14828.6 KIY44037.1 - 0.0055 15.6 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Amnionless TMEM154 PF15102.6 KIY44037.1 - 0.0075 16.2 0.1 0.024 14.5 0.1 1.9 1 0 0 1 1 1 1 TMEM154 protein family DUF1192 PF06698.11 KIY44037.1 - 0.017 15.1 1.0 0.31 11.1 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4690 PF15756.5 KIY44037.1 - 0.039 14.5 1.7 0.076 13.6 0.4 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DivIC PF04977.15 KIY44037.1 - 0.072 12.9 0.9 1.2 8.9 0.6 2.8 2 1 0 2 2 2 0 Septum formation initiator Orf78 PF06024.12 KIY44037.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) bZIP_1 PF00170.21 KIY44037.1 - 0.21 11.7 0.4 0.48 10.6 0.1 1.7 2 0 0 2 2 1 0 bZIP transcription factor Syndecan PF01034.20 KIY44037.1 - 0.22 11.5 0.2 0.42 10.5 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain bZIP_2 PF07716.15 KIY44037.1 - 0.4 10.8 1.5 0.62 10.2 0.2 1.9 3 0 0 3 3 3 0 Basic region leucine zipper Sugar_tr PF00083.24 KIY44039.1 - 3.6e-64 217.3 2.1 4.3e-64 217.0 2.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY44039.1 - 9.5e-16 57.6 5.7 1.2e-15 57.3 5.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY44039.1 - 0.0003 19.8 0.7 0.0003 19.8 0.7 2.1 2 0 0 2 2 2 1 MFS_1 like family DUF4131 PF13567.6 KIY44039.1 - 2.9 7.5 6.0 0.58 9.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Macro PF01661.21 KIY44040.1 - 1.4e-32 112.2 0.0 2.1e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Macro domain DUF5345 PF17280.2 KIY44041.1 - 5.6 7.0 6.6 0.7 9.9 1.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5345) MFS_1 PF07690.16 KIY44042.1 - 8.3e-29 100.6 54.5 1.7e-20 73.3 22.2 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY44042.1 - 6.7e-05 21.9 20.5 0.0006 18.8 4.9 2.5 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KIY44042.1 - 0.00044 19.2 4.7 0.00044 19.2 4.7 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Sde2_N_Ubi PF13019.6 KIY44043.1 - 8.9e-47 159.0 0.3 2.6e-46 157.4 0.0 1.7 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain GSHPx PF00255.19 KIY44044.1 - 3.4e-41 139.2 0.1 4.3e-41 138.9 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KIY44044.1 - 2.5e-05 24.2 0.0 7e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY44044.1 - 7.2e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 1 0 1 1 1 1 Redoxin Ral PF11058.8 KIY44044.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Antirestriction protein Ral Phosphonate-bd PF12974.7 KIY44044.1 - 0.19 11.3 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.16 KIY44045.1 - 1.1e-34 119.9 24.7 1.1e-34 119.9 24.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PIG-P PF08510.12 KIY44045.1 - 7.4 6.5 7.4 13 5.7 0.2 3.0 3 0 0 3 3 3 0 PIG-P Metallophos PF00149.28 KIY44046.1 - 2.7e-06 28.0 0.0 6.3e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY44046.1 - 0.0007 19.8 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain ORC6 PF05460.13 KIY44046.1 - 0.5 9.6 1.7 0.76 9.0 1.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) COX5B PF01215.19 KIY44047.1 - 1.1e-46 157.7 0.0 1.4e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 KIY44047.1 - 0.012 15.6 0.5 0.018 15.1 0.5 1.3 1 0 0 1 1 1 0 Zinc-finger domain Svf1_C PF17187.4 KIY44048.1 - 6.2e-48 162.7 0.0 1e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KIY44048.1 - 6.8e-42 143.3 0.0 9.8e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain VTC PF09359.10 KIY44049.1 - 4.8e-94 314.8 0.0 1.1e-93 313.7 0.0 1.6 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 KIY44049.1 - 2.9e-17 63.7 27.5 1.9e-07 31.4 0.2 4.3 2 1 2 4 4 4 4 SPX domain DUF202 PF02656.15 KIY44049.1 - 3.3e-11 43.4 1.1 7.1e-11 42.4 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Herpes_UL25 PF01499.16 KIY44049.1 - 0.12 10.8 1.9 0.24 9.9 1.9 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family Clp1 PF06807.14 KIY44049.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 COesterase PF00135.28 KIY44050.1 - 2.9e-55 188.1 0.0 5.4e-55 187.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY44050.1 - 2.8e-07 30.6 0.6 1e-06 28.8 0.2 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold RMI1_N PF08585.12 KIY44051.1 - 1.1e-29 103.8 0.0 1.3e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Carn_acyltransf PF00755.20 KIY44052.1 - 9.1e-154 513.3 0.0 1e-153 513.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase F-box-like PF12937.7 KIY44053.1 - 0.018 14.9 0.0 0.1 12.5 0.0 2.4 1 1 0 1 1 1 0 F-box-like MFS_1 PF07690.16 KIY44054.1 - 9e-14 51.1 36.4 1.8e-12 46.9 25.1 2.9 2 2 1 3 3 3 3 Major Facilitator Superfamily DAD PF02109.16 KIY44054.1 - 0.36 11.2 2.2 2.8 8.3 0.1 2.7 2 0 0 2 2 2 0 DAD family PLN_propep PF16485.5 KIY44055.1 - 1.2 8.9 4.8 7.8 6.3 0.3 2.4 2 0 0 2 2 2 0 Protealysin propeptide UvrD-helicase PF00580.21 KIY44056.1 - 9.1e-61 206.1 0.0 3.3e-60 204.3 0.0 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KIY44056.1 - 2e-59 201.8 0.0 8e-30 104.4 0.0 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KIY44056.1 - 2.2e-31 109.1 0.0 6.4e-31 107.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIY44056.1 - 2.9e-14 52.6 0.1 2e-13 50.0 0.1 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KIY44056.1 - 4.4e-09 36.4 0.6 0.019 14.7 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIY44056.1 - 0.00026 20.7 0.1 0.54 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KIY44056.1 - 0.0008 19.1 0.0 0.0051 16.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 KIY44057.1 - 6.4e-47 159.8 0.0 1.1e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KIY44057.1 - 3.2e-32 111.7 0.0 8.9e-30 103.7 0.0 2.9 2 1 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KIY44057.1 - 1.7e-06 28.6 0.0 9.7e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY44057.1 - 0.00012 22.3 0.0 0.00038 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KIY44057.1 - 0.0013 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin TsaE PF02367.17 KIY44057.1 - 0.0089 16.0 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CoaE PF01121.20 KIY44057.1 - 0.014 15.1 0.1 4.2 7.0 0.2 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase CPT PF07931.12 KIY44057.1 - 0.044 13.6 0.1 0.25 11.2 0.0 2.2 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 KIY44057.1 - 0.056 13.9 0.4 1 9.8 0.4 2.4 1 1 0 1 1 1 0 AAA domain HSP20 PF00011.21 KIY44058.1 - 0.0046 17.1 0.0 0.012 15.8 0.0 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family MAGI_u1 PF16663.5 KIY44058.1 - 0.024 14.7 0.5 0.053 13.6 0.1 1.7 2 0 0 2 2 2 0 Unstructured region on MAGI Thymopoietin PF08198.11 KIY44058.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Thymopoietin protein Glyco_hydro_76 PF03663.14 KIY44059.1 - 1e-23 84.5 4.9 1e-23 84.5 4.9 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 SPA PF08616.10 KIY44060.1 - 6.1e-10 39.1 0.0 9.8e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis RRM_1 PF00076.22 KIY44061.1 - 0.003 17.3 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B_2 PF12706.7 KIY44061.1 - 0.12 11.9 0.1 0.43 10.1 0.0 1.6 1 1 1 2 2 2 0 Beta-lactamase superfamily domain Pro_dh PF01619.18 KIY44062.1 - 8.7e-53 179.8 0.0 1.2e-51 176.0 0.0 2.1 1 1 0 1 1 1 1 Proline dehydrogenase Rubrerythrin PF02915.17 KIY44064.1 - 0.00038 20.9 3.0 0.00063 20.1 3.0 1.3 1 0 0 1 1 1 1 Rubrerythrin SPT2 PF08243.11 KIY44065.1 - 7.3e-17 61.9 14.5 7.3e-17 61.9 14.5 3.9 2 1 0 2 2 2 1 SPT2 chromatin protein Tubulin PF00091.25 KIY44066.1 - 5.2e-58 196.5 0.0 8.1e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY44066.1 - 8.5e-29 100.3 0.1 1.6e-28 99.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KIY44066.1 - 0.00047 19.9 0.0 0.00099 18.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KIY44066.1 - 0.017 15.4 0.4 0.041 14.2 0.0 1.8 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain Nucleocap_ssRNA PF11128.8 KIY44066.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid DUF1479 PF07350.12 KIY44067.1 - 2.4e-117 392.2 0.0 2.8e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KIY44067.1 - 0.065 13.5 0.9 1.9 8.7 0.2 2.5 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) CDC73_C PF05179.14 KIY44068.1 - 2.6e-52 176.7 0.3 4e-52 176.1 0.3 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KIY44068.1 - 8.3e-05 22.1 0.0 0.17 11.2 0.1 2.2 1 1 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal DUF1178 PF06676.11 KIY44068.1 - 0.013 15.8 0.1 0.023 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) IPK PF03770.16 KIY44069.1 - 1.6e-42 145.6 0.0 2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase RPAP1_C PF08620.10 KIY44070.1 - 2.3e-21 75.6 0.0 5.8e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KIY44070.1 - 5.2e-11 42.1 4.8 1.3e-10 40.9 4.8 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal Baculo_PEP_C PF04513.12 KIY44071.1 - 0.91 9.6 16.5 4.2e+02 0.9 16.5 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MgtE PF01769.16 KIY44072.1 - 1.4e-41 141.7 19.1 4.2e-23 82.1 11.8 3.1 2 1 1 3 3 3 2 Divalent cation transporter Ndc1_Nup PF09531.10 KIY44072.1 - 2.3 6.8 16.8 0.12 11.0 2.0 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup TPR_1 PF00515.28 KIY44074.1 - 1.5e-16 59.5 3.6 5.4e-07 29.2 0.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 KIY44074.1 - 5.5e-14 51.9 0.0 1.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.6 KIY44074.1 - 2e-13 49.4 3.5 1.3e-06 28.1 0.2 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY44074.1 - 2.6e-13 49.0 8.4 6.4e-05 22.8 0.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44074.1 - 3.5e-11 43.2 7.6 4e-08 33.4 1.5 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44074.1 - 2.7e-06 26.9 1.3 0.00041 20.0 0.2 3.5 3 1 1 4 4 3 1 TPR repeat TPR_7 PF13176.6 KIY44074.1 - 3.8e-06 26.5 6.3 0.00038 20.3 0.4 3.8 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY44074.1 - 6.3e-06 26.2 0.6 1.3 9.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY44074.1 - 2e-05 24.9 10.4 0.29 11.9 0.1 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY44074.1 - 0.00013 22.1 3.0 0.066 13.4 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44074.1 - 0.00048 20.7 1.3 0.00048 20.7 1.3 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44074.1 - 0.0023 18.4 1.6 0.025 15.1 0.4 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIY44074.1 - 0.0088 15.9 3.3 0.54 10.2 0.5 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY44074.1 - 0.012 15.8 0.6 0.03 14.5 0.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KIY44074.1 - 0.14 13.1 0.3 0.14 13.1 0.3 4.3 4 1 1 5 5 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 KIY44074.1 - 0.16 12.0 3.0 0.89 9.6 0.6 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 KIY44074.1 - 1.5 8.9 3.4 13 5.9 0.3 2.7 2 1 1 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 KIY44074.1 - 2.4 9.0 5.6 25 5.9 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PRIMA1 PF16101.5 KIY44074.1 - 9.9 6.2 10.5 3.8 7.6 1.6 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SUV3_C PF12513.8 KIY44075.1 - 4e-11 42.7 0.2 9.8e-11 41.4 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KIY44075.1 - 9.3e-10 38.8 0.0 1.8e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.22 KIY44076.1 - 2.3e-14 52.9 0.0 4.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_PH PF01138.21 KIY44078.1 - 1.1e-31 110.0 0.6 1.9e-31 109.3 0.6 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIY44078.1 - 1.4e-06 28.2 0.0 3.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Potyvirid-P3 PF13608.6 KIY44078.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein RasGAP PF00616.19 KIY44079.1 - 7.6e-59 198.9 0.0 2.9e-58 197.0 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KIY44079.1 - 4.9e-37 127.1 0.9 1.6e-36 125.5 0.1 2.3 2 0 0 2 2 2 1 RasGAP C-terminus DUF4393 PF14337.6 KIY44079.1 - 0.024 14.4 0.2 0.11 12.3 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4393) FA_desaturase PF00487.24 KIY44080.1 - 1.7e-14 54.3 23.4 2.8e-14 53.6 23.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIY44080.1 - 3.6e-13 49.5 0.0 6.5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Aldo_ket_red PF00248.21 KIY44081.1 - 5.5e-47 160.4 0.0 1e-45 156.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 KIY44082.1 - 8.9e-58 196.0 0.0 1.2e-57 195.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY44082.1 - 3.1e-31 108.8 0.0 5.8e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY44082.1 - 5.7e-05 23.3 0.1 0.00019 21.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY44082.1 - 0.00031 20.4 0.2 0.0039 16.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIY44082.1 - 0.00082 18.5 0.6 0.0018 17.4 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIY44082.1 - 0.0015 17.7 1.5 0.012 14.7 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY44082.1 - 0.0027 17.0 0.2 0.0072 15.6 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY44082.1 - 0.007 15.6 0.2 0.013 14.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIY44082.1 - 0.016 14.4 0.2 0.035 13.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY44082.1 - 0.024 13.3 0.0 0.049 12.3 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KIY44082.1 - 0.18 12.1 0.0 0.49 10.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain RRM_1 PF00076.22 KIY44083.1 - 1.7e-14 53.3 0.1 2.7e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Tim10_DDP PF02953.15 KIY44084.1 - 1.5e-20 72.6 0.5 2.2e-20 72.1 0.4 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Homeodomain PF00046.29 KIY44085.1 - 1.1e-20 73.3 3.7 1.4e-20 72.8 3.7 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIY44085.1 - 0.0072 16.2 0.6 0.017 15.0 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 KIY44085.1 - 0.012 15.3 0.2 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 Homeodomain-like domain U1snRNP70_N PF12220.8 KIY44087.1 - 2.9e-26 91.9 2.6 5.5e-26 91.0 2.6 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KIY44087.1 - 1.5e-14 53.5 0.0 2.8e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARID PF01388.21 KIY44088.1 - 5.6e-13 49.4 0.0 2.4e-12 47.4 0.0 2.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain THOC7 PF05615.13 KIY44088.1 - 0.76 10.1 12.5 0.068 13.5 3.7 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 ThiF PF00899.21 KIY44090.1 - 1.8e-57 194.5 0.0 2.6e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KIY44090.1 - 4.8e-11 43.1 0.0 2.1e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KIY44090.1 - 0.041 13.9 0.2 0.096 12.8 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KIY44090.1 - 0.17 11.5 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KIY44090.1 - 0.75 9.4 2.5 22 4.7 0.0 2.6 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA Amidohydro_1 PF01979.20 KIY44091.1 - 4e-66 223.7 1.7 7.9e-66 222.7 1.7 1.5 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KIY44091.1 - 7.4e-55 184.5 1.6 1.5e-54 183.5 1.6 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KIY44091.1 - 9.2e-42 141.0 0.1 2.5e-41 139.6 0.1 1.8 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KIY44091.1 - 4.8e-41 139.1 0.2 1.8e-40 137.2 0.1 2.2 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KIY44091.1 - 7.4e-06 25.7 0.3 9.2e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family MMtag PF10159.9 KIY44092.1 - 1.2e-30 105.6 1.8 1.2e-30 105.6 1.8 2.4 2 0 0 2 2 2 1 Multiple myeloma tumor-associated SelP_N PF04592.14 KIY44092.1 - 2.6 7.4 9.0 4.5 6.6 9.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Nitrate_red_gam PF02665.14 KIY44093.1 - 0.049 13.2 0.4 0.091 12.3 0.4 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Sugar_tr PF00083.24 KIY44094.1 - 1e-113 380.6 16.2 1.1e-113 380.5 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY44094.1 - 5.7e-23 81.4 28.4 6.5e-21 74.6 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KIY44096.1 - 4.8e-68 229.4 0.0 5.8e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44096.1 - 2.2e-30 105.8 0.0 3.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY44096.1 - 0.00087 18.3 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY44096.1 - 0.0053 16.1 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY44096.1 - 0.035 13.4 0.2 0.062 12.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY44096.1 - 0.063 13.2 0.1 0.25 11.3 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family NicO PF03824.16 KIY44097.1 - 5.7e-49 167.0 10.7 9.6e-48 162.9 2.0 2.4 2 1 0 2 2 2 2 High-affinity nickel-transport protein Ribosomal_L16 PF00252.18 KIY44098.1 - 5e-45 152.7 0.0 6.1e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Methyltransf_4 PF02390.17 KIY44099.1 - 3.1e-51 173.3 0.0 3.9e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KIY44099.1 - 0.00032 21.3 0.1 0.0021 18.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY44099.1 - 0.0077 16.0 0.1 0.11 12.3 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY44099.1 - 0.0096 16.6 0.0 0.024 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY44099.1 - 0.014 16.0 0.0 0.045 14.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIY44099.1 - 0.089 12.3 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Citrate_synt PF00285.21 KIY44100.1 - 2.5e-97 326.2 0.0 2.9e-97 326.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Roughex PF06020.11 KIY44106.1 - 9.9 5.1 10.3 23 3.9 10.3 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Cauli_VI PF01693.16 KIY44107.1 - 3.4e-06 27.3 0.0 4.1e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Caulimovirus viroplasmin CxC2 PF18803.1 KIY44108.1 - 0.0013 18.8 1.0 0.0016 18.6 0.1 1.6 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIY44109.1 - 5.6e-32 110.1 0.6 5.6e-32 110.1 0.6 1.6 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY44109.1 - 0.03 14.5 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Ribosomal_S26e PF01283.19 KIY44111.1 - 8.4e-53 177.4 8.9 1.1e-52 177.0 8.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Gpr1_Fun34_YaaH PF01184.19 KIY44112.1 - 2.1e-31 109.2 21.5 2.4e-31 109.0 21.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family EIF_2_alpha PF07541.12 KIY44114.1 - 1.8e-34 118.3 0.0 2.7e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KIY44114.1 - 2e-12 47.2 1.0 3.4e-12 46.5 1.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Ribosomal_60s PF00428.19 KIY44114.1 - 4.6 7.9 6.6 1.9 9.1 0.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein ATP19 PF11022.8 KIY44115.1 - 5.8e-13 49.0 1.8 1e-09 38.6 0.0 3.1 2 1 1 3 3 3 3 ATP synthase subunit K Serinc PF03348.15 KIY44116.1 - 8.9e-156 519.1 10.0 1e-155 518.9 10.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2569 PF10754.9 KIY44116.1 - 0.00094 19.6 1.4 0.00094 19.6 1.4 3.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2569) CENP-B_dimeris PF09026.10 KIY44116.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Adaptin_N PF01602.20 KIY44117.1 - 1.8e-119 399.7 1.5 3.1e-119 398.9 1.5 1.3 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIY44117.1 - 1.1e-16 61.3 6.1 7.7e-14 52.0 0.3 3.7 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY44117.1 - 5.5e-09 36.3 4.0 0.0014 19.0 0.1 3.8 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KIY44117.1 - 9.9e-08 32.3 2.6 0.004 17.6 0.2 3.9 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KIY44117.1 - 0.00031 20.7 9.0 2.7 8.5 0.1 5.9 6 0 0 6 6 6 2 HEAT repeat DUF3384 PF11864.8 KIY44117.1 - 0.0023 16.9 0.2 0.012 14.5 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) Cohesin_HEAT PF12765.7 KIY44117.1 - 0.43 10.9 3.3 2.6 8.4 0.1 3.4 4 0 0 4 4 3 0 HEAT repeat associated with sister chromatid cohesion Pox_Ag35 PF03286.14 KIY44117.1 - 0.59 9.9 7.2 1.2 8.9 7.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KIY44117.1 - 5.8 6.1 7.9 12 5.1 7.9 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KIY44117.1 - 6 4.9 13.9 9.8 4.2 13.9 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.6 KIY44117.1 - 7.6 6.0 7.5 7 6.2 5.2 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain DnaJ PF00226.31 KIY44118.1 - 6e-17 61.5 0.0 1.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Frag1 PF10277.9 KIY44119.1 - 3.8e-25 88.7 7.0 3.8e-25 88.7 7.0 2.9 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family DHDPS PF00701.22 KIY44120.1 - 2.6e-38 131.4 0.0 3.3e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KIY44120.1 - 0.00077 19.0 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF1154 PF06631.11 KIY44120.1 - 0.24 11.5 0.0 0.71 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) SCP2 PF02036.17 KIY44121.1 - 1.7e-23 83.0 2.7 2.1e-23 82.7 2.7 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KIY44121.1 - 3.1e-07 30.7 1.3 3.9e-07 30.4 1.3 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal bMG3 PF11974.8 KIY44121.1 - 0.035 14.1 0.2 0.085 12.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain p450 PF00067.22 KIY44122.1 - 2e-50 171.9 0.0 3e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TRAM_LAG1_CLN8 PF03798.16 KIY44123.1 - 1.3e-35 123.0 27.1 1.3e-35 123.0 27.1 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KIY44123.1 - 2.6e-10 39.8 0.1 2.6e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 TRAM1-like protein ADH_zinc_N PF00107.26 KIY44124.1 - 2.8e-14 53.2 0.0 5.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY44124.1 - 0.00083 19.2 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TPR_2 PF07719.17 KIY44125.1 - 2.8e-29 98.9 4.0 1.3e-05 24.9 0.0 8.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIY44125.1 - 2.5e-27 93.5 0.0 4.2e-06 26.3 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY44125.1 - 5.7e-24 84.1 1.0 2e-10 40.7 0.0 5.8 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KIY44125.1 - 2.1e-22 79.2 6.9 1e-09 38.5 0.0 7.8 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY44125.1 - 2.8e-22 77.0 0.0 3.8e-06 26.7 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44125.1 - 4.6e-20 72.0 5.8 6.9e-08 33.0 0.0 5.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44125.1 - 4.4e-17 61.5 0.2 4.3e-07 29.5 0.0 6.1 6 1 1 7 7 7 3 TPR repeat TPR_7 PF13176.6 KIY44125.1 - 6.6e-16 57.1 0.4 0.00021 21.1 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44125.1 - 1.5e-13 51.0 0.0 0.0013 19.2 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIY44125.1 - 2.1e-13 49.6 4.1 0.037 13.9 0.1 6.6 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY44125.1 - 2.7e-12 46.2 0.6 0.0014 18.8 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY44125.1 - 2.9e-12 46.4 5.8 0.02 15.5 0.0 6.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44125.1 - 7e-10 38.9 6.3 0.51 11.3 0.0 7.0 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY44125.1 - 1.6e-07 31.4 7.2 0.094 12.9 0.1 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 KIY44125.1 - 2.3e-07 30.8 4.2 1.3 9.9 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIY44125.1 - 1.1e-06 28.3 0.0 0.00011 21.7 0.0 3.6 3 1 1 4 4 4 1 MalT-like TPR region TPR_3 PF07720.12 KIY44125.1 - 0.00017 21.5 0.2 3.4 7.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Cohesin_load PF10345.9 KIY44125.1 - 0.16 10.3 0.0 0.79 8.1 0.0 1.9 2 0 0 2 2 2 0 Cohesin loading factor Fis1_TPR_C PF14853.6 KIY44125.1 - 0.7 10.0 6.3 1.1e+02 3.0 0.0 4.9 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Pkinase PF00069.25 KIY44126.1 - 6.7e-64 215.8 0.0 8.6e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44126.1 - 7e-36 123.8 0.0 9.4e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY44126.1 - 3e-08 33.3 0.0 5.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY44126.1 - 0.00015 20.6 0.0 0.00029 19.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KIY44126.1 - 0.00035 19.6 0.2 0.00052 19.1 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY44126.1 - 0.0017 18.3 0.2 0.003 17.5 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY44126.1 - 0.1 11.9 0.3 0.22 10.8 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 KIY44127.1 - 6.5e-13 48.3 23.3 6.5e-13 48.3 23.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY44127.1 - 5.2e-08 32.8 4.6 5.2e-08 32.8 4.6 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 SNARE_assoc PF09335.11 KIY44128.1 - 8.3e-10 39.2 6.0 2.2e-09 37.8 6.0 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein Lipase_GDSL PF00657.22 KIY44129.1 - 7.6e-09 35.8 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIY44129.1 - 1e-05 26.0 0.1 8.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family APG17 PF04108.12 KIY44130.1 - 2.6e-71 240.8 15.4 2.9e-71 240.7 15.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Phos_pyr_kin PF08543.12 KIY44130.1 - 0.054 12.9 0.1 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase COG5 PF10392.9 KIY44130.1 - 0.084 13.1 8.9 0.53 10.5 0.3 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF812 PF05667.11 KIY44130.1 - 0.26 10.1 11.9 0.82 8.5 11.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) YojJ PF10372.9 KIY44130.1 - 0.48 10.5 2.9 18 5.5 0.2 3.4 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus CorA PF01544.18 KIY44130.1 - 0.71 9.1 5.5 0.94 8.7 4.4 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Noelin-1 PF12308.8 KIY44130.1 - 1.1 9.3 8.2 1.1 9.3 0.7 3.5 3 0 0 3 3 3 0 Neurogenesis glycoprotein SpecificRecomb PF10136.9 KIY44130.1 - 1.5 7.1 6.5 2.4 6.4 6.5 1.3 1 0 0 1 1 1 0 Site-specific recombinase DUF3322 PF11795.8 KIY44130.1 - 1.8 8.5 8.6 0.27 11.2 1.9 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) LMBR1 PF04791.16 KIY44130.1 - 4.2 6.2 5.5 25 3.6 5.4 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein TSNAXIP1_N PF15739.5 KIY44130.1 - 5.8 7.3 8.1 2.1 8.8 1.2 3.4 3 1 0 3 3 3 0 Translin-associated factor X-interacting N-terminus Abhydrolase_6 PF12697.7 KIY44133.1 - 1.4e-08 35.7 1.7 1.7e-08 35.4 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KIY44133.1 - 9.2e-08 32.0 0.0 1.8e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KIY44133.1 - 1.1e-07 31.4 0.3 8e-07 28.6 0.3 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY44133.1 - 3.6e-07 30.1 0.1 6.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acyl_transf_2 PF02273.15 KIY44133.1 - 0.046 12.9 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 Acyl transferase DDE_Tnp_ISAZ013 PF07592.11 KIY44133.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.4 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain PHBC_N PF12551.8 KIY44133.1 - 0.28 11.0 2.7 0.39 10.5 0.3 2.3 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal MFS_1 PF07690.16 KIY44134.1 - 3.2e-12 46.1 25.6 3.2e-12 46.1 25.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY44134.1 - 1.5e-07 31.3 5.0 1.5e-07 31.3 5.0 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Methyltr_RsmB-F PF01189.17 KIY44135.1 - 2e-39 135.3 0.0 1.7e-36 125.7 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KIY44135.1 - 0.0014 18.8 0.0 0.0037 17.4 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF2431 PF10354.9 KIY44135.1 - 0.015 15.6 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_31 PF13847.6 KIY44135.1 - 0.22 11.3 0.0 0.63 9.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Rad51 PF08423.11 KIY44136.1 - 7.7e-19 67.9 0.0 1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KIY44136.1 - 3e-08 33.3 0.3 1.2e-06 28.0 0.3 2.5 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KIY44136.1 - 1.6e-07 31.0 0.1 2.5e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KIY44136.1 - 0.00012 21.8 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY44136.1 - 0.0088 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIY44136.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 KIY44136.1 - 0.014 14.7 0.1 0.05 12.9 0.1 1.9 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain Maf1 PF09174.10 KIY44137.1 - 1.5e-39 136.0 0.0 4.3e-31 108.4 0.0 2.1 2 0 0 2 2 2 2 Maf1 regulator Complex1_LYR PF05347.15 KIY44138.1 - 2.6e-07 30.6 1.0 5.5e-07 29.5 0.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIY44138.1 - 0.12 13.2 1.6 0.16 12.7 1.6 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Zn_ribbon_17 PF17120.5 KIY44139.1 - 2.4e-06 27.0 11.6 2.4e-06 27.0 11.6 2.5 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KIY44139.1 - 5.2e-06 27.1 0.4 5.2e-06 27.1 0.4 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat DZR PF12773.7 KIY44139.1 - 4.1 7.5 12.3 8.5 6.5 12.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon NPR3 PF03666.13 KIY44141.1 - 2.3e-85 287.2 0.1 1e-83 281.7 0.1 2.1 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF489 PF04356.12 KIY44141.1 - 0.033 14.2 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF2610 PF11020.8 KIY44141.1 - 0.064 13.1 0.0 2.9 7.8 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2610) eIF-1a PF01176.19 KIY44142.1 - 2.6e-23 81.6 0.0 3.7e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 UcrQ PF02939.16 KIY44143.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.7 1 1 1 2 2 2 0 UcrQ family TPR_2 PF07719.17 KIY44144.1 - 4.1e-11 42.1 8.1 0.00019 21.3 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY44144.1 - 7.1e-08 32.6 4.2 0.00012 22.2 0.6 2.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KIY44144.1 - 8.4e-08 31.7 8.6 2.9e-05 23.7 1.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44144.1 - 1.5e-07 31.6 4.2 0.014 16.2 0.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44144.1 - 1.9e-06 28.4 7.0 1.6e-05 25.4 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44144.1 - 9.5e-06 26.0 4.2 2.1e-05 24.9 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY44144.1 - 5.4e-05 23.6 6.7 0.13 12.9 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44144.1 - 0.00011 22.4 4.8 0.031 14.6 0.6 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.20 KIY44144.1 - 0.00032 20.7 0.3 0.77 10.1 0.0 2.8 2 1 0 2 2 2 2 PPR repeat TPR_7 PF13176.6 KIY44144.1 - 0.00049 19.9 0.7 4.2 7.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44144.1 - 0.00092 18.8 5.6 0.028 14.1 0.3 3.0 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 KIY44144.1 - 0.0029 17.9 2.6 0.039 14.3 0.2 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat PPR_2 PF13041.6 KIY44144.1 - 0.005 17.0 0.9 2.2 8.6 0.3 2.5 2 0 0 2 2 2 1 PPR repeat family TPM_phosphatase PF04536.14 KIY44144.1 - 0.0058 16.8 0.2 3.8 7.7 0.0 2.5 2 0 0 2 2 2 2 TPM domain BTAD PF03704.17 KIY44144.1 - 0.022 15.2 2.7 0.11 12.9 2.7 1.9 1 1 0 1 1 1 0 Bacterial transcriptional activator domain SMG1 PF15785.5 KIY44144.1 - 0.028 12.8 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 TPR_9 PF13371.6 KIY44144.1 - 0.18 12.0 1.1 0.38 10.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIY44144.1 - 0.31 11.4 7.1 0.11 12.8 2.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 KIY44144.1 - 0.32 10.8 1.9 13 5.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Alkyl_sulf_dimr PF14863.6 KIY44144.1 - 0.73 10.3 6.7 1 9.8 0.4 2.7 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation HSP20 PF00011.21 KIY44145.1 - 2.5e-07 30.8 0.0 0.0024 18.0 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY44145.1 - 5.3e-07 29.1 0.0 8.3e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA FbpC_C_terminal PF17845.1 KIY44145.1 - 0.14 12.3 0.2 0.54 10.4 0.2 2.1 1 1 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain gpW PF02831.15 KIY44146.1 - 0.12 12.2 0.1 0.61 10.0 0.1 2.2 2 1 0 2 2 2 0 gpW Phosphonate-bd PF12974.7 KIY44147.1 - 0.00017 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 KIY44147.1 - 0.00028 20.9 0.0 0.00074 19.5 0.0 1.6 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_3 PF16868.5 KIY44147.1 - 0.015 14.7 0.0 0.039 13.4 0.0 1.6 2 0 0 2 2 2 0 NMT1-like family NMT1_2 PF13379.6 KIY44147.1 - 0.041 13.6 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 NMT1-like family LysR_substrate PF03466.20 KIY44147.1 - 0.1 12.0 0.0 0.39 10.0 0.0 1.8 1 1 0 1 1 1 0 LysR substrate binding domain Methyltransf_31 PF13847.6 KIY44148.1 - 7.9e-14 51.7 0.0 1.1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY44148.1 - 9.3e-08 32.7 0.1 3.7e-07 30.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY44148.1 - 2.3e-07 31.5 0.0 4.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY44148.1 - 3.6e-05 24.3 0.1 0.00021 21.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY44148.1 - 0.0034 17.2 0.0 0.0059 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KIY44148.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KIY44148.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UPF0086 PF01868.16 KIY44149.1 - 3.6e-26 90.9 0.0 5.5e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Med26 PF08711.11 KIY44150.1 - 8.7e-10 38.5 0.1 2.7e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain STAT_int PF02865.17 KIY44151.1 - 0.082 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 STAT protein, protein interaction domain AAA_12 PF13087.6 KIY44152.1 - 4.4e-32 111.3 0.1 6.6e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY44152.1 - 9.1e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY44152.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY44152.1 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIY44152.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KIY44152.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 KIY44153.1 - 8.3e-10 38.9 0.1 1.3e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY44153.1 - 3.1e-07 30.3 0.2 5.6e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY44153.1 - 6.3e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIY44153.1 - 0.00016 22.0 0.0 0.0003 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KIY44153.1 - 0.0054 16.7 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KIY44153.1 - 0.0066 15.9 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein ATPase PF06745.13 KIY44153.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 KIY44153.1 - 0.012 14.8 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KIY44153.1 - 0.013 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KIY44153.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIY44153.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KIY44153.1 - 0.023 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIY44153.1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIY44153.1 - 0.057 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KIY44153.1 - 0.079 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 KIY44153.1 - 0.15 11.2 0.1 0.28 10.3 0.1 1.4 1 0 0 1 1 1 0 PIF1-like helicase Rad17 PF03215.15 KIY44153.1 - 0.15 12.0 0.0 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain DnaJ PF00226.31 KIY44154.1 - 6.3e-19 67.9 0.8 1.8e-18 66.4 0.1 2.2 3 0 0 3 3 2 1 DnaJ domain TPR_1 PF00515.28 KIY44154.1 - 1.3e-15 56.4 1.3 0.0013 18.5 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY44154.1 - 3.4e-14 51.7 10.7 0.0088 16.1 0.0 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44154.1 - 1.3e-11 44.9 9.3 2.5e-07 31.2 1.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44154.1 - 2.1e-11 43.6 11.4 0.0012 19.5 0.9 6.2 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY44154.1 - 9.6e-10 37.9 2.5 0.16 12.3 0.1 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44154.1 - 2.7e-08 33.3 3.0 0.00061 19.4 0.6 4.1 3 1 1 4 4 4 2 TPR repeat TPR_19 PF14559.6 KIY44154.1 - 7.4e-08 32.8 8.6 0.0036 17.8 1.7 5.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44154.1 - 1.7e-07 31.4 13.1 0.1 12.9 1.8 6.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIY44154.1 - 0.0004 20.2 6.5 17 5.7 0.0 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY44154.1 - 0.00084 19.8 5.2 2.6 8.9 0.0 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY44154.1 - 0.0015 18.8 13.2 0.25 11.6 1.5 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KIY44154.1 - 0.0047 16.8 6.3 0.66 9.9 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY44154.1 - 0.0064 16.6 4.8 0.13 12.5 0.3 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.9 KIY44154.1 - 0.0072 15.1 0.5 0.037 12.8 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_17 PF13431.6 KIY44154.1 - 0.013 15.8 2.7 2 9.0 0.6 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 KIY44154.1 - 0.019 14.1 0.1 0.077 12.1 0.0 1.9 2 0 0 2 2 2 0 Spatacsin C-terminus BTAD PF03704.17 KIY44154.1 - 0.019 15.4 0.2 0.019 15.4 0.2 3.9 2 2 2 4 4 4 0 Bacterial transcriptional activator domain RPT PF13446.6 KIY44154.1 - 0.04 13.8 0.0 0.23 11.4 0.0 2.3 2 1 1 3 3 3 0 A repeated domain in UCH-protein TPR_4 PF07721.14 KIY44154.1 - 2 9.3 10.7 11 7.0 0.3 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Pam16 PF03656.13 KIY44155.1 - 6.1e-06 26.3 0.1 2.8e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KIY44155.1 - 0.00079 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Dyp_perox PF04261.12 KIY44155.1 - 0.0014 17.7 0.0 0.0016 17.5 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Hydrolase_4 PF12146.8 KIY44156.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPR_19 PF14559.6 KIY44158.1 - 3.5e-10 40.2 4.0 0.0052 17.3 0.4 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44158.1 - 6e-09 36.4 5.6 6.5e-05 23.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIY44158.1 - 4.2e-08 33.0 0.9 0.039 14.3 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY44158.1 - 0.0015 18.5 10.0 17 5.8 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44158.1 - 0.0015 18.8 7.7 0.19 12.1 0.1 4.5 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44158.1 - 0.0095 16.7 11.6 12 7.0 1.4 6.0 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY44158.1 - 0.018 14.8 4.9 13 5.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIY44158.1 - 0.02 15.3 1.0 0.12 12.8 0.2 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 KIY44158.1 - 0.078 12.9 1.1 1.1 9.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_assoc_2 PF16193.5 KIY44158.1 - 0.11 12.8 0.2 0.64 10.4 0.0 2.4 3 0 0 3 3 3 0 AAA C-terminal domain TPR_9 PF13371.6 KIY44158.1 - 0.19 11.9 6.0 5.5 7.2 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4880 PF16220.5 KIY44158.1 - 0.22 11.4 9.7 4.1 7.4 4.9 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4880) TPR_6 PF13174.6 KIY44158.1 - 0.23 12.2 13.1 15 6.5 0.1 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY44158.1 - 0.66 10.3 4.1 39 4.8 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat BCNT PF07572.12 KIY44163.1 - 1.1e-17 63.9 1.6 1.3e-17 63.6 0.2 1.8 2 0 0 2 2 2 1 Bucentaur or craniofacial development UPF0220 PF05255.11 KIY44164.1 - 2.4e-54 183.3 0.1 3e-54 183.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Amidase PF01425.21 KIY44165.1 - 2.8e-101 339.7 0.0 3.3e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Amidase AftA_C PF12249.8 KIY44167.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.4 1 1 1 2 2 2 0 Arabinofuranosyltransferase A C terminal Paramyxo_P PF01806.17 KIY44167.1 - 0.22 10.9 0.0 0.29 10.6 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region GFO_IDH_MocA PF01408.22 KIY44168.1 - 1e-17 65.1 0.0 2e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIY44168.1 - 7.6e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain THF_DHG_CYH PF00763.23 KIY44168.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain TPR_1 PF00515.28 KIY44169.1 - 2.6e-13 49.1 2.0 8.3e-05 22.2 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44169.1 - 3.5e-11 42.6 1.9 0.00011 21.8 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.17 KIY44169.1 - 1.2e-10 40.6 10.6 0.00018 21.3 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY44169.1 - 3.2e-09 36.5 0.8 0.00058 20.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44169.1 - 9.5e-06 26.0 3.7 0.078 13.5 3.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44169.1 - 0.00012 22.6 8.6 0.018 15.7 1.5 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44169.1 - 0.0006 20.4 5.6 0.77 10.7 0.6 3.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY44169.1 - 0.0011 19.0 5.1 0.73 10.2 0.4 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY44169.1 - 0.0012 18.8 1.5 3.1 8.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 KIY44169.1 - 0.15 12.1 3.4 2 8.5 0.4 2.4 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain PA28_alpha PF02251.18 KIY44170.1 - 0.00036 20.5 0.0 0.37 10.9 0.0 2.6 2 0 0 2 2 2 2 Proteasome activator pa28 alpha subunit zf_CCCH_4 PF18345.1 KIY44171.1 - 9.1e-11 41.4 33.0 5.9e-06 26.1 10.7 3.3 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 KIY44171.1 - 1.1e-09 38.9 17.7 9.9e-06 26.2 1.9 3.4 1 1 2 3 3 3 3 Torus domain zf-CCCH PF00642.24 KIY44171.1 - 2.6e-09 36.7 24.5 0.00064 19.6 7.6 3.2 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIY44171.1 - 2.7e-08 33.4 9.1 2.7e-08 33.4 9.1 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KIY44171.1 - 0.1 12.8 14.6 2.5 8.3 1.8 3.3 2 1 2 4 4 4 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KIY44171.1 - 6.5 7.4 24.2 2.1 9.0 7.5 3.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger NCE101 PF11654.8 KIY44172.1 - 1.1e-16 60.2 0.1 1.4e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 TRAPP PF04051.16 KIY44173.1 - 5.2e-35 120.3 0.0 6.6e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component HNH_2 PF13391.6 KIY44176.1 - 5.3e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 1 0 1 1 1 1 HNH endonuclease Phage_antitermQ PF06530.12 KIY44176.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q Glyco_transf_15 PF01793.16 KIY44177.1 - 6.4e-108 360.8 7.0 7.6e-108 360.6 7.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase BNR PF02012.20 KIY44177.1 - 0.11 12.6 0.3 0.28 11.4 0.3 1.8 1 0 0 1 1 1 0 BNR/Asp-box repeat Ribosomal_L1 PF00687.21 KIY44178.1 - 6.7e-58 195.8 0.3 8.9e-58 195.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Peptidase_M22 PF00814.25 KIY44179.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family Lyase_8_N PF08124.11 KIY44179.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain zf-MYND PF01753.18 KIY44180.1 - 1.7e-10 40.8 7.8 1.7e-10 40.8 7.8 2.1 2 0 0 2 2 2 1 MYND finger zf_C2H2_13 PF18508.1 KIY44180.1 - 0.064 12.9 1.4 0.36 10.4 0.1 2.4 1 1 1 2 2 2 0 Zinc finger domain zf-C6H2 PF15801.5 KIY44180.1 - 0.073 13.4 6.1 0.2 12.0 6.1 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Methyltransf_23 PF13489.6 KIY44181.1 - 2.8e-10 40.3 0.0 3.6e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY44181.1 - 1.9e-06 28.4 0.0 3.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY44181.1 - 0.00019 22.0 0.0 0.00035 21.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY44181.1 - 0.0032 17.3 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY44181.1 - 0.013 16.2 0.0 0.11 13.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain PPI_Ypi1 PF07491.11 KIY44182.1 - 9.5e-24 83.0 4.0 9.5e-24 83.0 4.0 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.12 KIY44182.1 - 0.16 10.5 3.7 0.18 10.4 3.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_A_bac PF01000.26 KIY44185.1 - 5.6e-24 84.7 0.0 1.1e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KIY44185.1 - 2.6e-18 65.2 0.0 7.6e-18 63.7 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cadherin_4 PF17803.1 KIY44186.1 - 0.032 14.9 2.4 0.032 14.9 2.4 1.5 2 0 0 2 2 2 0 Bacterial cadherin-like domain Hepsin-SRCR PF09272.10 KIY44186.1 - 0.048 14.2 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 Hepsin, SRCR domain Pkinase PF00069.25 KIY44187.1 - 1.9e-48 165.2 0.0 2.7e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44187.1 - 6.8e-24 84.5 0.1 3.9e-22 78.8 0.1 2.6 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY44187.1 - 5.3e-08 32.1 0.0 6.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY44187.1 - 6.2e-07 29.0 0.0 3.9e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KIY44187.1 - 0.00028 20.9 0.1 0.003 17.5 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY44187.1 - 0.011 15.1 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EGF_2 PF07974.13 KIY44188.1 - 0.0013 19.0 22.4 0.0029 18.0 13.9 6.0 7 1 0 7 7 7 2 EGF-like domain TRI9 PF08195.11 KIY44191.1 - 0.099 12.5 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 TRI9 protein MPM1 PF17234.2 KIY44194.1 - 0.088 13.1 0.0 0.098 12.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Kdo PF06293.14 KIY44195.1 - 0.07 12.5 0.2 0.15 11.3 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ala_racemase_N PF01168.20 KIY44197.1 - 5.3e-14 52.4 0.0 2.4e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain HalX PF08663.10 KIY44197.1 - 1.1 9.7 5.5 19 5.6 0.3 3.2 3 0 0 3 3 3 0 HalX domain O-FucT PF10250.9 KIY44202.1 - 3.3e-11 43.5 0.0 2e-05 24.5 0.0 3.0 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase ABC2_membrane PF01061.24 KIY44204.1 - 4.5e-32 111.2 20.8 4.5e-32 111.2 20.8 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KIY44204.1 - 5.2e-27 95.0 0.0 9.5e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY44204.1 - 7.1e-05 22.8 0.1 0.3 10.9 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KIY44204.1 - 0.0039 16.3 22.0 0.0039 16.3 22.0 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 KIY44204.1 - 0.0044 16.5 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain EGF_2 PF07974.13 KIY44204.1 - 0.012 16.0 13.8 0.012 16.0 13.8 4.5 5 0 0 5 5 3 0 EGF-like domain Rad17 PF03215.15 KIY44204.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KIY44204.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIY44204.1 - 0.032 14.1 0.3 0.087 12.7 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase Calici_MSP PF05752.11 KIY44204.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein AAA_16 PF13191.6 KIY44204.1 - 0.062 13.7 0.7 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KIY44204.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KIY44204.1 - 0.083 12.5 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIY44204.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY44204.1 - 0.15 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIY44204.1 - 0.18 12.3 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KIY44205.1 - 8.8e-47 159.7 0.0 1.3e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44205.1 - 1.7e-23 83.2 0.0 4.2e-22 78.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY44205.1 - 3.8e-08 32.5 0.0 4.5e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY44205.1 - 4.7e-06 26.1 0.1 2.9e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KIY44205.1 - 0.00021 21.3 0.1 0.0023 17.9 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY44205.1 - 0.0043 16.4 0.1 0.007 15.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LEA_6 PF10714.9 KIY44206.1 - 0.1 12.7 1.6 0.25 11.5 0.4 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 DUF5380 PF17351.2 KIY44206.1 - 0.13 12.1 0.0 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5380) Meth_synt_2 PF01717.18 KIY44208.1 - 1.9e-17 63.6 0.0 6.4e-17 61.8 0.0 1.8 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIY44208.1 - 0.013 15.0 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain DOCK_N PF16172.5 KIY44208.1 - 0.17 10.7 0.1 0.27 10.1 0.1 1.1 1 0 0 1 1 1 0 DOCK N-terminus Kdo PF06293.14 KIY44211.1 - 0.021 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kdo PF06293.14 KIY44212.1 - 0.0065 15.9 0.1 0.012 14.9 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Meth_synt_2 PF01717.18 KIY44218.1 - 3.1e-16 59.6 0.0 1.1e-15 57.7 0.0 1.8 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIY44218.1 - 0.014 15.0 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KIY44218.1 - 0.026 13.7 0.0 0.082 12.0 0.0 1.8 2 1 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) DOCK_N PF16172.5 KIY44218.1 - 0.22 10.4 0.1 0.33 9.8 0.1 1.2 1 0 0 1 1 1 0 DOCK N-terminus MutS_V PF00488.21 KIY44220.1 - 3.7e-82 274.9 0.0 6.1e-82 274.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIY44220.1 - 1.5e-35 123.1 0.2 3.7e-35 121.9 0.2 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KIY44220.1 - 6.3e-16 58.5 2.4 1.3e-15 57.5 0.9 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 KIY44220.1 - 8.8e-13 48.7 0.0 4.2e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 KIY44220.1 - 1.1e-07 32.1 0.0 3.4e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 KIY44220.1 - 0.074 12.6 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain TFIIF_beta PF02270.15 KIY44221.1 - 1.2e-28 99.1 0.4 1.9e-28 98.4 0.4 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KIY44221.1 - 4.6e-19 69.4 0.0 8.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus zf-NOSIP PF15906.5 KIY44222.1 - 3.1e-12 46.5 0.2 3.1e-12 46.5 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KIY44222.1 - 2.1e-07 30.8 13.1 0.0016 18.4 1.1 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY44222.1 - 5.2e-07 29.4 17.6 0.002 17.9 8.2 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY44222.1 - 5.4e-06 26.3 18.0 6.2e-05 22.9 6.6 3.1 2 2 1 3 3 3 2 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY44222.1 - 8.1e-06 25.6 15.7 0.0004 20.2 1.5 3.3 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIY44222.1 - 9e-06 25.9 16.3 0.0054 17.0 7.7 2.7 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 KIY44222.1 - 1.9e-05 24.4 14.9 0.012 15.5 4.8 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY44222.1 - 2.3e-05 24.1 20.2 0.022 14.6 2.1 4.0 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY44222.1 - 0.0018 18.4 14.7 0.11 12.6 1.6 3.4 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING FCP1_C PF09309.10 KIY44222.1 - 0.013 15.4 5.7 0.016 15.1 3.0 2.1 2 1 1 3 3 3 0 FCP1, C-terminal zf-RING_10 PF16685.5 KIY44222.1 - 0.019 15.1 14.5 0.041 14.0 6.6 2.9 2 1 1 3 3 3 0 zinc RING finger of MSL2 DUF4685 PF15737.5 KIY44222.1 - 0.04 14.4 3.0 0.093 13.2 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) FYVE PF01363.21 KIY44222.1 - 0.063 13.4 13.4 0.052 13.7 5.0 2.9 2 2 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 KIY44222.1 - 0.37 10.8 11.1 1 9.4 3.3 2.6 2 1 0 2 2 2 0 zinc-ribbons zf-RING_6 PF14835.6 KIY44222.1 - 1.6 8.6 8.3 1 9.3 0.5 2.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Glyco_transf_22 PF03901.17 KIY44223.1 - 7.8e-36 124.2 19.2 9.7e-36 123.9 19.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family BRE1 PF08647.11 KIY44224.1 - 0.0004 20.4 10.5 0.0004 20.4 10.5 2.5 1 1 1 2 2 2 1 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 KIY44224.1 - 0.0074 16.5 26.4 0.23 11.6 12.8 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) FliD_C PF07195.12 KIY44224.1 - 0.023 14.1 8.6 0.66 9.3 8.6 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.10 KIY44224.1 - 0.031 14.5 13.6 0.023 14.9 10.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GNVR PF13807.6 KIY44224.1 - 0.034 14.1 2.3 0.061 13.2 2.3 1.4 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase HMMR_N PF15905.5 KIY44224.1 - 0.045 13.2 22.2 0.37 10.2 11.1 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3857 PF12969.7 KIY44224.1 - 0.058 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) Mod_r PF07200.13 KIY44224.1 - 0.13 12.4 21.3 0.13 12.4 13.0 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 KIY44224.1 - 0.2 11.0 21.7 0.13 11.6 8.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding T2SSF PF00482.23 KIY44224.1 - 0.37 10.7 4.8 0.41 10.6 0.3 2.2 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein F KxDL PF10241.9 KIY44224.1 - 1.2 9.5 11.9 2.9 8.2 4.8 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein Fez1 PF06818.15 KIY44224.1 - 1.2 9.5 22.6 0.17 12.3 10.2 2.0 1 1 1 2 2 2 0 Fez1 AAA_13 PF13166.6 KIY44224.1 - 1.3 7.5 16.4 1.6 7.3 16.4 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 KIY44224.1 - 1.3 8.0 17.8 1.2 8.2 16.6 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 KIY44224.1 - 1.4 9.3 19.0 0.17 12.2 4.9 3.1 1 1 2 3 3 3 0 Tup N-terminal Nup54 PF13874.6 KIY44224.1 - 1.8 8.6 19.8 0.31 11.1 7.3 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Rho_Binding PF08912.11 KIY44224.1 - 2.3 9.1 19.2 5.7 7.8 8.8 3.3 1 1 2 3 3 3 0 Rho Binding MPS2 PF17060.5 KIY44224.1 - 4.1 6.6 12.0 6.3 5.9 12.0 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 ADIP PF11559.8 KIY44224.1 - 7.6 6.6 24.2 2.2 8.4 9.8 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BTB PF00651.31 KIY44225.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain F-box-like PF12937.7 KIY44226.1 - 3.2e-05 23.7 0.1 8.7e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY44226.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 F-box zf-H2C2_2 PF13465.6 KIY44227.1 - 1.5e-10 41.0 9.4 6e-05 23.3 0.7 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KIY44227.1 - 1e-07 32.0 14.7 2.3e-05 24.6 1.0 4.2 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY44227.1 - 1.4e-06 28.7 7.2 0.0063 17.3 0.5 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIY44227.1 - 0.00098 18.8 1.0 0.00098 18.8 1.0 3.1 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KIY44227.1 - 0.0035 17.6 6.8 0.0089 16.3 4.4 2.7 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KIY44227.1 - 0.0091 16.7 0.6 0.037 14.7 0.0 2.1 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats AAA_12 PF13087.6 KIY44227.1 - 0.057 13.0 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF629 PF04780.12 KIY44227.1 - 0.092 11.3 2.1 1 7.8 1.5 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF629) FOXP-CC PF16159.5 KIY44227.1 - 0.11 13.1 4.4 0.67 10.6 0.1 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-BED PF02892.15 KIY44227.1 - 5.4 7.1 9.7 0.72 9.9 2.8 2.7 2 1 0 2 2 2 0 BED zinc finger GAGA PF09237.11 KIY44227.1 - 5.6 6.8 6.9 20 5.1 2.7 3.0 1 1 1 2 2 2 0 GAGA factor Polysacc_deac_1 PF01522.21 KIY44228.1 - 6.6e-25 87.4 0.0 1.1e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1404 PF07185.11 KIY44228.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1404) GST_N PF02798.20 KIY44229.1 - 0.0052 17.1 0.0 0.0086 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY44229.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PIN PF01850.21 KIY44229.1 - 0.012 16.1 0.0 0.014 15.9 0.0 1.1 1 0 0 1 1 1 0 PIN domain GST_N_2 PF13409.6 KIY44229.1 - 0.031 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Pkinase_fungal PF17667.1 KIY44230.1 - 6.9e-14 51.4 0.1 8.2e-14 51.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KIY44231.1 - 2e-15 56.5 0.0 2.3e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIY44231.1 - 7.3e-05 22.3 0.0 8.4e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44231.1 - 0.0052 16.1 0.0 0.0056 16.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Cpn60_TCP1 PF00118.24 KIY44232.1 - 2.3e-80 270.6 2.3 2.6e-80 270.4 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CdAMP_rec PF06153.11 KIY44232.1 - 0.05 13.8 0.1 0.73 10.1 0.0 2.3 2 0 0 2 2 2 0 Cyclic-di-AMP receptor Lon_C PF05362.13 KIY44233.1 - 5e-66 222.2 0.4 8.7e-66 221.4 0.4 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KIY44233.1 - 8.1e-36 123.8 0.0 1.6e-35 122.9 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KIY44233.1 - 2e-21 76.8 0.0 5.5e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIY44233.1 - 6.3e-08 32.7 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY44233.1 - 1.5e-05 25.2 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KIY44233.1 - 1.8e-05 23.9 0.0 3.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 KIY44233.1 - 0.00016 22.1 0.0 0.00058 20.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KIY44233.1 - 0.00018 21.3 0.0 0.001 18.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIY44233.1 - 0.00023 21.5 0.0 0.0026 18.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain ChlI PF13541.6 KIY44233.1 - 0.00095 19.0 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_18 PF13238.6 KIY44233.1 - 0.0012 19.4 0.5 0.0036 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain SPX PF03105.19 KIY44233.1 - 0.0023 17.9 3.3 0.0027 17.7 1.5 1.9 2 0 0 2 2 2 1 SPX domain AAA_14 PF13173.6 KIY44233.1 - 0.003 17.6 0.0 0.0079 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY44233.1 - 0.0087 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein SKI PF01202.22 KIY44233.1 - 0.0089 16.2 0.0 0.1 12.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase RNA_helicase PF00910.22 KIY44233.1 - 0.0094 16.3 0.1 0.091 13.2 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 KIY44233.1 - 0.036 14.3 0.0 6.2 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIY44233.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIY44233.1 - 0.056 12.6 0.1 0.21 10.8 0.1 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain RsgA_GTPase PF03193.16 KIY44233.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 KIY44233.1 - 0.062 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain ATPase_2 PF01637.18 KIY44233.1 - 0.079 12.9 1.2 11 5.8 0.0 3.1 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KIY44233.1 - 0.094 12.6 0.2 0.5 10.3 0.1 2.2 1 1 1 2 2 2 0 NTPase NB-ARC PF00931.22 KIY44233.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KIY44233.1 - 0.1 13.1 0.1 0.37 11.3 0.1 1.9 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KIY44233.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KIY44233.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KIY44233.1 - 0.14 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KIY44233.1 - 0.16 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIY44233.1 - 0.2 11.8 0.5 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain YABBY PF04690.13 KIY44234.1 - 1.2e-09 38.9 5.2 1.2e-09 38.9 5.2 1.7 2 0 0 2 2 2 1 YABBY protein HMG_box PF00505.19 KIY44234.1 - 1.9e-08 34.6 1.5 3.4e-08 33.8 1.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY44234.1 - 1.3e-06 28.9 2.5 2.6e-06 27.9 2.5 1.6 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KIY44234.1 - 0.011 16.2 3.6 0.011 16.2 3.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 DUF5327 PF17261.2 KIY44234.1 - 7.1 7.4 8.9 3.7 8.4 6.6 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5327) F-box-like_2 PF13013.6 KIY44235.1 - 0.0051 16.8 0.0 0.029 14.3 0.0 2.4 2 1 0 2 2 2 1 F-box-like domain TRAP_alpha PF03896.16 KIY44236.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SRTM1 PF15872.5 KIY44236.1 - 0.043 14.0 1.7 0.043 14.0 1.7 1.7 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 HemY_N PF07219.13 KIY44236.1 - 0.065 13.4 3.5 5.9 7.1 0.2 2.3 2 0 0 2 2 2 0 HemY protein N-terminus Tad PF13400.6 KIY44236.1 - 0.17 12.2 0.3 0.17 12.2 0.3 2.4 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Gram_pos_anchor PF00746.21 KIY44236.1 - 1.4 8.9 3.9 0.42 10.6 0.2 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif zf-MYND PF01753.18 KIY44237.1 - 6.5e-09 35.7 17.2 1.1e-08 35.0 17.2 1.4 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 KIY44237.1 - 1.5e-06 28.6 0.1 0.48 11.1 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY44237.1 - 0.00015 22.3 0.0 0.0016 19.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIY44237.1 - 0.031 14.7 0.6 2.7 8.6 0.3 3.2 2 1 0 2 2 2 0 Ankyrin repeat zf-C6H2 PF15801.5 KIY44237.1 - 0.57 10.5 11.6 1 9.7 11.6 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 KIY44238.1 - 9.2e-32 110.3 34.6 1.4e-31 109.7 34.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NiFe_hyd_3_EhaA PF17367.2 KIY44238.1 - 2.5 8.3 12.9 0.17 12.0 0.6 3.4 3 1 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF1752 PF08550.10 KIY44239.1 - 4e-08 33.0 0.0 5.4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.24 KIY44240.1 - 2.4e-07 29.8 0.0 2.7e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase_fungal PF17667.1 KIY44241.1 - 2.7e-18 65.9 0.1 3e-18 65.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Cpn60_TCP1 PF00118.24 KIY44242.1 - 3.2e-20 72.2 1.8 2.9e-19 69.1 1.8 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family SnoaL_4 PF13577.6 KIY44242.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Pkinase_fungal PF17667.1 KIY44243.1 - 1.8e-21 76.4 0.1 2e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Antig_Caf1 PF09255.10 KIY44243.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Caf1 Capsule antigen zf-MYND PF01753.18 KIY44244.1 - 3.5e-12 46.2 11.5 6.7e-12 45.3 11.5 1.5 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 KIY44244.1 - 1.2e-07 32.1 0.1 0.0023 18.5 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY44244.1 - 2.9e-05 24.6 0.1 5.3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ecl1 PF12855.7 KIY44244.1 - 0.00021 22.5 0.1 0.00037 21.7 0.1 1.3 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Ank_5 PF13857.6 KIY44244.1 - 0.0059 16.9 0.1 0.16 12.3 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-C6H2 PF15801.5 KIY44244.1 - 0.014 15.7 3.5 0.029 14.7 3.5 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding tRNA-synt_1c PF00749.21 KIY44245.1 - 9.3e-35 120.0 0.1 1.1e-34 119.8 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Aldo_ket_red PF00248.21 KIY44246.1 - 4.7e-72 242.7 0.0 5.4e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase_fungal PF17667.1 KIY44247.1 - 4.3e-16 58.7 0.0 1.5e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase FliD_C PF07195.12 KIY44247.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Pkinase_fungal PF17667.1 KIY44249.1 - 7.4e-21 74.4 0.0 9.1e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIY44249.1 - 0.00035 20.0 0.0 0.00089 18.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44249.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Retrotran_gag_2 PF14223.6 KIY44252.1 - 6.2e-12 45.4 0.1 6.8e-12 45.2 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type LPD5 PF18799.1 KIY44252.1 - 0.0069 16.8 0.1 0.0078 16.6 0.1 1.1 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 5 Pkinase_fungal PF17667.1 KIY44253.1 - 6.7e-21 74.5 0.0 9.3e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIY44253.1 - 1e-05 25.0 0.0 6.7e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44253.1 - 0.00043 19.6 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY44254.1 - 2.4e-20 72.7 0.2 2.7e-20 72.6 0.2 1.0 1 0 0 1 1 1 1 Fungal protein kinase PS_Dcarbxylase PF02666.15 KIY44255.1 - 1.5e-58 197.7 0.0 2.3e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KIY44255.1 - 7.7e-27 93.6 0.0 5.1e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain HATPase_c_3 PF13589.6 KIY44256.1 - 0.018 14.9 0.0 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF87 PF01935.17 KIY44256.1 - 0.19 11.8 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain F-box-like PF12937.7 KIY44259.1 - 4.8e-06 26.4 1.5 8.1e-06 25.6 0.3 2.0 2 0 0 2 2 2 1 F-box-like Chromo PF00385.24 KIY44260.1 - 4.4e-11 42.5 0.1 8e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3552 PF12072.8 KIY44260.1 - 0.0072 15.8 4.7 0.014 14.8 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Chromo PF00385.24 KIY44261.1 - 6.3e-07 29.2 0.9 1.4e-06 28.1 0.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain KDGP_aldolase PF07071.11 KIY44261.1 - 0.0071 16.2 1.4 0.026 14.3 0.5 2.1 2 0 0 2 2 2 1 KDGP aldolase GAS PF13851.6 KIY44261.1 - 0.64 9.3 53.2 0.089 12.1 14.3 4.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HOOK PF05622.12 KIY44261.1 - 3.1 5.8 53.9 0.12 10.5 11.5 3.8 3 1 1 4 4 4 0 HOOK protein DUF4710 PF15828.5 KIY44261.1 - 3.8 7.7 5.6 15 5.8 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) F-box-like PF12937.7 KIY44263.1 - 0.076 12.9 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 F-box-like DNA_pol3_a_NI PF14480.6 KIY44263.1 - 0.15 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I HMw1_D2 PF18254.1 KIY44265.1 - 0.097 13.0 0.0 19 5.7 0.0 2.5 1 1 1 2 2 2 0 HMW1 domain 2 F-box-like PF12937.7 KIY44266.1 - 0.00015 21.6 0.0 0.00047 20.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like HATPase_c_3 PF13589.6 KIY44268.1 - 0.0067 16.3 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF87 PF01935.17 KIY44268.1 - 0.012 15.8 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain PTCB-BRCT PF12738.7 KIY44269.1 - 4.4e-06 26.6 0.0 5.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KIY44269.1 - 0.065 13.6 0.0 0.065 13.6 0.0 1.1 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain p450 PF00067.22 KIY44270.1 - 2e-22 79.6 0.0 5.8e-21 74.8 0.1 2.1 1 1 1 2 2 2 2 Cytochrome P450 Nop14 PF04147.12 KIY44271.1 - 0.0035 15.7 22.3 0.0057 14.9 22.3 1.4 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 KIY44271.1 - 0.0089 15.4 24.3 0.018 14.4 24.3 1.5 1 0 0 1 1 1 1 BUD22 Nucleo_P87 PF07267.11 KIY44271.1 - 0.048 12.5 9.6 0.11 11.3 9.6 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TALPID3 PF15324.6 KIY44272.1 - 0.42 8.2 5.5 0.6 7.7 5.5 1.3 1 0 0 1 1 1 0 Hedgehog signalling target Gti1_Pac2 PF09729.9 KIY44273.1 - 9e-22 78.0 0.1 2.8e-19 69.9 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family ABC_tran PF00005.27 KIY44274.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ABC2_membrane PF01061.24 KIY44274.1 - 0.13 11.7 4.4 0.24 10.8 4.4 1.4 1 0 0 1 1 1 0 ABC-2 type transporter Plavaka PF18759.1 KIY44276.1 - 8.2e-75 252.0 1.2 4.6e-47 160.8 0.1 2.1 1 1 1 2 2 2 2 Plavaka transposase Transposase_21 PF02992.14 KIY44280.1 - 7e-10 38.5 2.0 2.1e-09 36.9 0.4 2.2 2 1 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.12 KIY44280.1 - 4.7e-06 26.3 0.0 8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Cwf_Cwc_15 PF04889.12 KIY44281.1 - 2 8.1 13.7 0.92 9.2 11.7 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_MLP1_2 PF07926.12 KIY44284.1 - 0.0032 17.5 13.3 0.0032 17.5 13.3 5.2 3 2 2 5 5 5 2 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KIY44284.1 - 0.02 15.1 2.5 0.02 15.1 2.5 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper RAP1 PF07218.11 KIY44285.1 - 4.6 5.4 6.6 6.3 5.0 6.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) STE3 PF02076.15 KIY44286.1 - 2.1e-43 148.6 15.4 2.7e-43 148.2 15.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor bZIP_1 PF00170.21 KIY44287.1 - 0.12 12.5 5.0 0.2 11.8 5.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor Methyltransf_31 PF13847.6 KIY44288.1 - 6.3e-25 87.7 0.0 8.6e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY44288.1 - 3.1e-20 72.7 0.3 8.9e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY44288.1 - 3.2e-19 69.4 0.4 1.1e-18 67.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY44288.1 - 1.5e-16 60.4 0.1 3.7e-16 59.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIY44288.1 - 8.5e-12 45.2 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY44288.1 - 9.6e-09 35.9 0.0 1.7e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY44288.1 - 1.3e-06 28.4 0.0 8.1e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KIY44288.1 - 9.4e-06 25.2 0.1 1.6e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KIY44288.1 - 0.00042 19.7 0.0 0.00061 19.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KIY44288.1 - 0.00076 19.4 0.1 0.0012 18.7 0.1 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KIY44288.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 KIY44288.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 ADH_zinc_N PF00107.26 KIY44288.1 - 0.0028 17.6 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 KIY44288.1 - 0.0053 16.8 0.5 0.0065 16.5 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 KIY44288.1 - 0.017 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPF0020 PF01170.18 KIY44288.1 - 0.047 13.4 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ApoO PF09769.9 KIY44290.1 - 7e-22 77.8 0.0 1.3e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein O Phasin PF05597.11 KIY44290.1 - 0.048 13.7 0.6 4.8 7.2 0.0 2.6 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fungal_trans PF04082.18 KIY44291.1 - 1.2e-24 86.8 0.0 1.7e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KIY44292.1 - 9.6e-26 90.4 0.0 3.5e-25 88.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY44292.1 - 0.00014 21.9 5.3 0.00014 21.9 5.3 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY44293.1 - 4.6e-26 91.4 0.0 6.9e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY44293.1 - 3.5e-05 23.8 3.7 3.5e-05 23.8 3.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KIY44294.1 - 1.2e-07 31.4 0.0 0.0078 15.6 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Fic PF02661.18 KIY44295.1 - 1.9e-11 44.7 0.1 2.9e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Fic/DOC family Fic PF02661.18 KIY44296.1 - 3.9e-11 43.7 0.1 1.9e-10 41.5 0.0 2.1 2 1 0 2 2 2 1 Fic/DOC family Trehalase PF01204.18 KIY44297.1 - 0.00022 20.2 0.1 0.014 14.2 0.0 2.0 1 1 1 2 2 2 2 Trehalase NMT_C PF02799.15 KIY44297.1 - 0.016 14.8 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain GHMP_kinases_C PF08544.13 KIY44298.1 - 0.088 13.2 0.0 0.17 12.3 0.0 1.4 1 1 0 1 1 1 0 GHMP kinases C terminal p450 PF00067.22 KIY44299.1 - 0.0012 17.7 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1479 PF07350.12 KIY44300.1 - 0.08 11.7 0.2 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) KDZ PF18758.1 KIY44302.1 - 8.9e-69 231.5 2.1 1.2e-68 231.0 2.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY44302.1 - 0.001 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases RT_RNaseH PF17917.1 KIY44305.1 - 5.5e-06 26.6 0.1 6.5e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase OS-D PF03392.13 KIY44306.1 - 0.23 11.6 5.1 0.057 13.5 1.6 1.8 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D KDZ PF18758.1 KIY44307.1 - 2.4e-71 239.9 1.3 2.8e-71 239.7 1.3 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase RVP_2 PF08284.11 KIY44310.1 - 0.03 14.1 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF835 PF05763.12 KIY44310.1 - 0.18 11.5 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF835) F-box PF00646.33 KIY44313.1 - 3.7e-05 23.5 0.3 0.00014 21.7 0.3 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY44313.1 - 0.00051 19.9 0.9 0.0012 18.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like GLE1 PF07817.13 KIY44314.1 - 4.3e-51 173.5 0.0 7.4e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein DUF2151 PF10221.9 KIY44314.1 - 0.35 9.4 11.1 0.49 8.9 11.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator zf-C3HC4_3 PF13920.6 KIY44315.1 - 2.7e-06 27.1 8.1 5.1e-06 26.2 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY44315.1 - 3.8e-05 23.9 12.7 3.8e-05 23.9 12.7 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 KIY44315.1 - 0.00044 20.1 8.5 0.00087 19.2 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY44315.1 - 0.00079 19.2 10.1 0.0015 18.3 10.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIY44315.1 - 0.0058 16.6 10.0 0.064 13.3 7.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY44315.1 - 0.018 14.9 10.6 0.041 13.8 10.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KIY44315.1 - 0.045 13.5 6.7 0.081 12.7 6.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KIY44315.1 - 0.046 13.9 5.3 0.12 12.5 5.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING T3SS_HrpK1 PF16937.5 KIY44315.1 - 0.054 13.1 0.8 0.085 12.5 0.8 1.3 1 0 0 1 1 1 0 Type III secretion system translocator protein, HrpF GCP_N_terminal PF17681.1 KIY44315.1 - 0.093 12.3 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal zf-RING_10 PF16685.5 KIY44315.1 - 0.89 9.7 6.0 1.9 8.7 6.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 KIY44315.1 - 1.1 9.4 11.9 0.15 12.2 5.5 2.6 3 1 1 4 4 4 0 FYVE zinc finger zf-C3HC4_2 PF13923.6 KIY44315.1 - 1.8 8.5 11.5 4.1 7.3 11.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Hexapep PF00132.24 KIY44316.1 - 1.6e-06 27.6 9.1 0.00034 20.2 0.9 3.3 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KIY44316.1 - 3.1e-06 27.0 0.0 4.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIY44316.1 - 5.3e-05 23.6 0.0 9.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KIY44316.1 - 0.00021 19.6 0.3 0.00046 18.5 0.2 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KIY44316.1 - 0.0094 14.9 0.3 0.027 13.4 0.3 1.7 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 KIY44316.1 - 0.019 14.7 1.9 0.54 10.1 1.0 2.6 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Lactonase PF10282.9 KIY44317.1 - 6.4e-09 35.5 0.0 1.3e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller zf-C2H2 PF00096.26 KIY44318.1 - 0.095 13.2 0.2 0.41 11.2 0.2 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type TIM PF00121.18 KIY44319.1 - 1e-88 296.8 0.0 1.2e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 KIY44319.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 CutC family Pilin_GH PF16734.5 KIY44319.1 - 0.051 13.9 0.2 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative CMAS PF02353.20 KIY44320.1 - 1.4e-67 227.9 0.1 1.7e-67 227.6 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KIY44320.1 - 1.7e-11 44.6 0.0 3e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY44320.1 - 1.8e-11 44.6 0.2 1.9e-10 41.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY44320.1 - 2.5e-11 43.7 0.0 5e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY44320.1 - 1.9e-07 31.7 0.0 5.6e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY44320.1 - 5.7e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY44320.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 KIY44320.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.13 KIY44320.1 - 0.0033 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KIY44320.1 - 0.0041 16.7 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KIY44320.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KIY44320.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F IBV_3C PF03620.13 KIY44320.1 - 0.19 12.2 2.5 1.3 9.6 0.1 2.5 2 0 0 2 2 2 0 IBV 3C protein RSN1_7TM PF02714.15 KIY44321.1 - 3.4e-77 259.5 19.9 6.9e-77 258.4 19.9 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIY44321.1 - 2.6e-34 118.3 5.2 1e-33 116.3 5.2 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIY44321.1 - 2e-31 109.6 0.0 2.9e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter CFEM PF05730.11 KIY44322.1 - 4.9e-10 39.4 15.3 4.9e-10 39.4 15.3 1.9 2 0 0 2 2 2 1 CFEM domain tRNA-synt_2c PF01411.19 KIY44323.1 - 3.5e-216 719.0 0.0 5.1e-216 718.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KIY44323.1 - 1.3e-16 60.4 0.4 4.5e-16 58.7 0.2 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KIY44323.1 - 1.5e-15 57.9 2.5 4.3e-15 56.4 2.5 1.8 1 0 0 1 1 1 1 DHHA1 domain SLX9 PF15341.6 KIY44323.1 - 0.02 15.3 0.8 0.059 13.8 0.8 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 eIF-3c_N PF05470.12 KIY44324.1 - 1.7e-171 571.5 21.3 2.3e-170 567.8 21.3 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KIY44324.1 - 7.9e-11 42.4 0.0 5.9e-10 39.6 0.0 2.5 2 0 0 2 2 2 1 PCI domain DinI PF06183.13 KIY44324.1 - 0.38 11.1 1.6 7 7.1 0.1 3.4 3 0 0 3 3 3 0 DinI-like family GCIP PF13324.6 KIY44324.1 - 2.2 7.8 7.9 0.26 10.8 1.3 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF2408 PF10303.9 KIY44324.1 - 7.5 7.1 7.4 7.4 7.2 2.9 3.2 4 1 0 4 4 4 0 Protein of unknown function (DUF2408) SRP_TPR_like PF17004.5 KIY44325.1 - 9.2e-14 51.5 0.0 1.4e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_19 PF14559.6 KIY44325.1 - 4.5e-08 33.5 0.2 0.0017 18.8 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat SRP72 PF08492.12 KIY44325.1 - 1.9e-06 28.2 0.1 1.9e-06 28.2 0.1 2.6 3 0 0 3 3 3 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 KIY44325.1 - 1.2e-05 25.4 0.8 0.023 14.9 0.1 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KIY44325.1 - 1.8e-05 24.5 1.4 0.1 12.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44325.1 - 0.00026 21.5 0.0 0.65 11.0 0.0 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY44325.1 - 0.0052 16.6 0.4 3.1 7.8 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY44325.1 - 0.0078 16.8 0.3 11 6.9 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY44325.1 - 0.024 14.8 0.5 0.42 10.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY44325.1 - 0.096 12.8 0.0 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KIY44325.1 - 0.15 12.4 2.9 0.68 10.3 0.1 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Pinin_SDK_memA PF04696.13 KIY44326.1 - 2.1e-12 47.2 11.1 3e-09 37.0 8.4 2.4 2 0 0 2 2 2 2 pinin/SDK/memA/ protein conserved region Glyco_hydro_115 PF15979.5 KIY44327.1 - 5.3e-126 420.7 0.8 6.9e-126 420.3 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KIY44327.1 - 4.8e-55 186.0 0.0 9.9e-55 185.0 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Phosphodiest PF01663.22 KIY44328.1 - 1e-11 45.0 0.7 2.8e-11 43.6 0.4 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KIY44328.1 - 5.5e-05 22.7 0.4 0.00011 21.6 0.4 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KIY44328.1 - 0.0093 15.4 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 Sulfatase SET PF00856.28 KIY44329.1 - 7.6e-16 59.0 0.2 4.1e-15 56.6 0.2 2.0 1 1 0 1 1 1 1 SET domain Neuropep_like PF15161.6 KIY44329.1 - 0.13 12.0 0.5 6.1 6.6 0.0 3.2 3 0 0 3 3 3 0 Neuropeptide-like Sec61_beta PF03911.16 KIY44330.1 - 6.7e-17 61.2 0.7 8.7e-17 60.9 0.7 1.2 1 0 0 1 1 1 1 Sec61beta family zf-RING_2 PF13639.6 KIY44331.1 - 9.7e-10 38.6 10.2 1.5e-09 38.0 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIY44331.1 - 1.3e-08 34.7 7.8 1.8e-08 34.2 7.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY44331.1 - 9e-08 31.9 7.2 1.3e-07 31.3 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY44331.1 - 1.7e-07 31.1 8.0 1e-06 28.6 8.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY44331.1 - 3.5e-06 26.8 11.1 5.7e-06 26.1 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY44331.1 - 2.1e-05 24.3 9.7 3.8e-05 23.5 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY44331.1 - 5.1e-05 23.1 10.1 0.00013 21.8 10.2 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIY44331.1 - 0.00016 21.4 9.1 0.00024 20.9 9.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.21 KIY44331.1 - 0.00078 19.5 3.9 0.011 15.8 0.3 2.2 1 1 1 2 2 2 1 FYVE zinc finger zf-RING_11 PF17123.5 KIY44331.1 - 0.0059 16.3 4.3 0.014 15.2 4.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KIY44331.1 - 0.01 15.9 9.3 0.057 13.6 9.4 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 KIY44331.1 - 0.012 15.0 0.1 0.016 14.6 0.1 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_6 PF14835.6 KIY44331.1 - 0.18 11.7 5.2 0.36 10.7 5.2 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 KIY44331.1 - 0.22 11.5 1.5 0.42 10.6 1.5 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-HIT PF04438.16 KIY44331.1 - 0.3 11.0 4.4 0.98 9.4 2.1 2.2 2 0 0 2 2 2 0 HIT zinc finger Zf_RING PF16744.5 KIY44331.1 - 0.33 11.1 4.3 0.45 10.7 1.3 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger zf-rbx1 PF12678.7 KIY44331.1 - 0.88 9.9 9.1 2.1 8.7 9.1 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain Synaptobrevin PF00957.21 KIY44332.1 - 9.6e-30 102.2 0.4 1.3e-29 101.8 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KIY44332.1 - 1.1e-19 70.2 0.0 3.3e-19 68.7 0.0 1.8 1 1 0 1 1 1 1 Regulated-SNARE-like domain YwcE PF17368.2 KIY44332.1 - 0.084 13.5 0.1 0.22 12.2 0.1 1.6 1 0 0 1 1 1 0 Spore morphogenesis and germination YwcE TcpS PF17456.2 KIY44334.1 - 0.0024 17.9 0.1 0.0047 17.0 0.1 1.4 1 0 0 1 1 1 1 Toxin-coregulated pilus protein S JAKMIP_CC3 PF16034.5 KIY44334.1 - 0.0033 17.4 3.4 0.0051 16.8 3.4 1.2 1 0 0 1 1 1 1 JAKMIP CC3 domain Prok-RING_4 PF14447.6 KIY44334.1 - 0.052 13.4 0.4 0.12 12.2 0.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Jnk-SapK_ap_N PF09744.9 KIY44334.1 - 0.44 10.8 4.8 0.75 10.0 4.3 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Macoilin PF09726.9 KIY44334.1 - 0.54 8.7 6.5 0.75 8.3 6.5 1.1 1 0 0 1 1 1 0 Macoilin family JIP_LZII PF16471.5 KIY44334.1 - 0.74 10.0 4.9 2.7 8.3 1.2 2.3 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 KIY44334.1 - 2.9 7.7 4.7 2.1 8.2 1.9 2.0 2 0 0 2 2 2 0 Septum formation initiator PUF PF00806.19 KIY44335.1 - 9.6e-25 84.8 0.2 3e-06 26.6 0.0 5.9 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat PSCyt1 PF07635.11 KIY44335.1 - 0.55 10.9 2.5 0.89 10.2 0.1 2.5 2 0 0 2 2 2 0 Planctomycete cytochrome C FAD_binding_1 PF00667.20 KIY44336.1 - 3.7e-37 128.1 0.0 5.2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KIY44336.1 - 5.5e-26 91.5 0.0 8.7e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KIY44336.1 - 8.9e-10 39.2 0.0 1.5e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KIY44336.1 - 0.041 14.1 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain EMG1 PF03587.14 KIY44337.1 - 2.9e-76 255.5 0.0 3.3e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase MAD PF05557.13 KIY44338.1 - 0.031 12.6 32.2 0.03 12.7 31.2 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein Atg14 PF10186.9 KIY44338.1 - 0.11 11.5 31.7 0.62 9.1 12.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DHR10 PF18595.1 KIY44338.1 - 0.12 12.4 41.7 0.48 10.5 24.6 4.0 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain FH2 PF02181.23 KIY44338.1 - 0.12 11.4 18.5 0.63 9.1 5.8 2.2 1 1 0 2 2 2 0 Formin Homology 2 Domain TPR_MLP1_2 PF07926.12 KIY44338.1 - 0.23 11.6 37.0 2.1 8.4 23.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 KIY44338.1 - 0.25 11.4 12.5 0.088 12.8 4.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 KIY44338.1 - 0.59 10.1 5.8 0.94 9.4 0.7 2.7 1 1 2 3 3 3 0 Apolipoprotein O Fez1 PF06818.15 KIY44338.1 - 0.81 10.1 35.7 2 8.8 19.7 2.1 1 1 1 2 2 2 0 Fez1 DUF3138 PF11336.8 KIY44338.1 - 1.4 7.4 7.4 2 7.0 7.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Tropomyosin_1 PF12718.7 KIY44338.1 - 1.7 8.8 39.3 4.7 7.4 8.8 3.0 1 1 2 3 3 3 0 Tropomyosin like AHSP PF09236.10 KIY44338.1 - 2.3 8.7 5.5 0.61 10.6 1.7 2.1 2 2 0 2 2 2 0 Alpha-haemoglobin stabilising protein Spc7 PF08317.11 KIY44338.1 - 3.3 6.5 39.6 1.2 7.9 18.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 KIY44338.1 - 6.3 6.1 35.0 0.92 8.8 11.1 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 KIY44338.1 - 7.6 6.3 48.7 0.72 9.6 20.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family BST2 PF16716.5 KIY44338.1 - 9 7.0 23.0 0.37 11.4 3.8 3.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 EF-hand_7 PF13499.6 KIY44339.1 - 4.3e-14 52.7 0.0 7.8e-08 32.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY44339.1 - 2.2e-12 45.8 0.3 2e-05 24.1 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KIY44339.1 - 8.5e-12 43.7 0.1 1.5e-05 24.2 0.1 3.6 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KIY44339.1 - 9.4e-08 32.3 0.0 0.0027 18.0 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KIY44339.1 - 1.8e-05 24.5 0.3 0.0017 18.2 0.1 3.1 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KIY44339.1 - 0.0053 16.2 0.4 0.0053 16.2 0.4 2.3 2 1 0 2 2 2 1 EF hand SapB_1 PF05184.15 KIY44339.1 - 0.054 13.5 0.1 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 RNA_pol_Rpb4 PF03874.16 KIY44339.1 - 0.069 13.5 0.0 7.9 6.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb4 EF-hand_11 PF08976.11 KIY44339.1 - 0.077 13.9 0.0 0.15 13.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DDE_Tnp_IS66_C PF13817.6 KIY44339.1 - 0.21 11.8 0.2 0.6 10.4 0.1 1.7 2 0 0 2 2 2 0 IS66 C-terminal element TFIIIC_delta PF12657.7 KIY44340.1 - 1.4e-08 34.9 0.0 0.0034 17.4 0.0 2.6 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KIY44340.1 - 5e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ANAPC4_WD40 PF12894.7 KIY44340.1 - 0.011 16.0 0.0 0.89 9.9 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RhoGEF PF00621.20 KIY44341.1 - 2.7e-30 106.0 0.0 5.3e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain AdoHcyase PF05221.17 KIY44342.1 - 9.9e-136 451.7 0.0 9.7e-75 251.5 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KIY44342.1 - 3.9e-81 270.9 0.4 6e-81 270.3 0.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIY44342.1 - 3.3e-07 29.8 0.1 8e-07 28.6 0.1 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIY44342.1 - 0.0039 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 KIY44342.1 - 0.019 14.5 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Vpu PF00558.19 KIY44343.1 - 0.055 13.2 1.3 0.13 12.1 1.3 1.5 1 0 0 1 1 1 0 Vpu protein DUF3419 PF11899.8 KIY44344.1 - 1.3e-132 442.7 0.5 1.7e-131 439.0 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KIY44344.1 - 4e-10 39.8 0.0 1.6e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY44344.1 - 1.1e-08 35.7 0.0 1.3e-07 32.2 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY44344.1 - 8.2e-07 29.6 0.0 0.00028 21.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY44344.1 - 1e-05 26.2 0.0 0.00044 21.0 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY44344.1 - 1.8e-05 24.2 0.0 0.00034 20.0 0.0 2.5 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIY44344.1 - 0.00037 20.3 0.0 0.0021 17.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIY44344.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase AA_permease_2 PF13520.6 KIY44345.1 - 6.2e-50 170.3 50.1 7.7e-50 170.0 50.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY44345.1 - 4.7e-21 74.9 44.4 6.1e-21 74.5 44.4 1.1 1 0 0 1 1 1 1 Amino acid permease RhoGAP PF00620.27 KIY44346.1 - 7.3e-46 155.7 0.1 3.8e-45 153.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KIY44346.1 - 2.1e-14 53.5 10.9 2.9e-08 33.8 5.6 2.9 2 1 1 3 3 3 2 LIM domain C1_1 PF00130.22 KIY44346.1 - 4.3e-06 26.5 7.7 4.3e-06 26.5 7.7 3.8 2 1 2 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KIY44346.1 - 0.0024 18.2 2.4 0.0024 18.2 2.4 3.6 2 1 0 2 2 2 1 C1 domain Suppressor_APC PF11414.8 KIY44346.1 - 0.059 13.4 0.6 0.22 11.6 0.6 2.0 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein YabA PF06156.13 KIY44346.1 - 0.61 10.8 8.5 0.2 12.3 0.8 3.3 2 1 2 4 4 4 0 Initiation control protein YabA TetR_C_6 PF13977.6 KIY44346.1 - 1.2 9.4 7.6 0.098 12.9 1.7 2.3 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal BTB PF00651.31 KIY44347.1 - 2.4e-11 43.9 0.0 1.8e-05 24.9 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain NB-ARC PF00931.22 KIY44348.1 - 9.4e-09 34.8 0.0 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIY44348.1 - 1.4e-08 35.3 0.4 9.8e-07 29.3 0.4 3.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY44348.1 - 7.1e-08 32.8 0.2 2.1e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY44348.1 - 4.3e-07 30.0 0.0 1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIY44348.1 - 0.00075 19.9 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIY44348.1 - 0.00085 19.1 0.0 0.0026 17.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY44348.1 - 0.013 15.6 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIY44348.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KIY44348.1 - 0.044 13.7 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KIY44348.1 - 0.065 13.6 0.1 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PI3K_rbd PF00794.18 KIY44348.1 - 0.14 12.3 0.4 0.67 10.1 0.1 2.2 2 0 0 2 2 2 0 PI3-kinase family, ras-binding domain ODC_AZ PF02100.17 KIY44349.1 - 5.7e-09 35.9 0.0 8.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme p450 PF00067.22 KIY44351.1 - 5.2e-51 173.8 0.1 6.6e-51 173.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S5 PF00333.20 KIY44352.1 - 1.2e-28 98.8 0.6 1.2e-28 98.8 0.6 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KIY44352.1 - 1.9e-23 81.7 0.0 3e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FXMRP1_C_core PF12235.8 KIY44352.1 - 1.3 9.6 4.3 2 9.0 4.3 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Oxidored_FMN PF00724.20 KIY44354.1 - 6.4e-75 252.5 0.0 7.7e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KIY44354.1 - 0.0027 17.4 0.1 0.0058 16.3 0.1 1.5 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) AP_endonuc_2 PF01261.24 KIY44354.1 - 0.11 11.9 0.0 0.51 9.7 0.0 1.9 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Peptidase_C1_2 PF03051.15 KIY44355.1 - 1.7e-156 521.4 0.0 2e-156 521.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KIY44355.1 - 9.8e-08 32.3 0.0 0.015 15.3 0.1 3.1 3 1 0 3 3 3 2 Papain family cysteine protease DNA_pol_B_palm PF14792.6 KIY44359.1 - 7.4e-24 84.2 0.0 1.4e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KIY44359.1 - 1.6e-21 76.2 0.0 3.2e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KIY44359.1 - 3.3e-20 71.6 0.0 1.3e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KIY44359.1 - 1.1e-12 48.1 0.0 2.3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KIY44359.1 - 0.0039 17.8 0.1 5 7.8 0.0 3.3 4 0 0 4 4 4 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KIY44359.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Ribosomal_L7Ae PF01248.26 KIY44361.1 - 9.4e-23 79.8 0.8 1.7e-22 79.0 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KIY44361.1 - 0.00055 20.0 0.1 0.0009 19.3 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Asp PF00026.23 KIY44362.1 - 1.5e-71 241.4 0.6 1.8e-71 241.2 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY44362.1 - 1.5e-13 51.4 5.9 1.1e-07 32.3 0.4 3.3 2 2 2 4 4 4 2 Xylanase inhibitor N-terminal GST_C PF00043.25 KIY44362.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_C15 PF01470.17 KIY44364.1 - 3.7e-12 46.8 0.1 3.9e-05 23.9 0.0 2.5 2 1 0 2 2 2 2 Pyroglutamyl peptidase NIF PF03031.18 KIY44365.1 - 5.5e-55 185.4 0.1 6.3e-55 185.2 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KIY44365.1 - 0.0051 17.2 0.1 0.054 13.9 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase p450 PF00067.22 KIY44366.1 - 3e-56 191.1 0.0 4.8e-56 190.4 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 TPP1 PF10341.9 KIY44367.1 - 9.5e-08 32.0 0.1 2.1e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Hira PF07569.11 KIY44367.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split Neur_chan_memb PF02932.16 KIY44367.1 - 6.8 6.7 5.3 3.3 7.7 1.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region APS_kinase PF01583.20 KIY44368.1 - 1.6e-71 239.3 0.0 1.9e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KIY44368.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY44368.1 - 0.00022 21.8 0.0 0.00033 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KIY44368.1 - 0.0018 17.8 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 KIY44368.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KIY44368.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 KIY44368.1 - 0.08 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit CPT PF07931.12 KIY44368.1 - 0.1 12.5 0.3 0.54 10.1 0.3 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PALP PF00291.25 KIY44369.1 - 3.6e-69 233.4 0.1 4.4e-69 233.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fib_alpha PF08702.10 KIY44370.1 - 0.029 14.6 14.5 0.24 11.6 4.4 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Borrelia_P83 PF05262.11 KIY44370.1 - 1.9 6.9 20.5 2.4 6.5 20.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4446 PF14584.6 KIY44370.1 - 2 8.4 0.0 2 8.4 0.0 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF4446) YMF19 PF02326.15 KIY44370.1 - 2.4 9.0 4.2 12 6.7 0.1 3.4 3 1 0 3 3 3 0 Plant ATP synthase F0 BLOC1_2 PF10046.9 KIY44370.1 - 2.7 8.3 10.0 5.5 7.4 1.5 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 KIY44370.1 - 5.8 5.4 12.8 26 3.2 2.3 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A AAA_23 PF13476.6 KIY44370.1 - 7.7 7.0 10.7 16 5.9 10.7 1.5 1 0 0 1 1 1 0 AAA domain NIF PF03031.18 KIY44371.1 - 7.9e-46 155.7 0.0 8.8e-46 155.5 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KIY44371.1 - 0.002 18.6 0.5 0.012 16.0 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase bZIP_1 PF00170.21 KIY44373.1 - 2.4e-07 30.7 24.8 7.4e-06 26.0 7.5 5.4 3 2 2 5 5 5 2 bZIP transcription factor HALZ PF02183.18 KIY44373.1 - 0.00047 20.3 6.1 2.5 8.4 0.4 3.9 3 1 1 4 4 4 2 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 KIY44373.1 - 0.00056 20.1 12.8 0.00056 20.1 12.8 3.2 3 0 0 3 3 2 1 Tropomyosin like Laminin_II PF06009.12 KIY44373.1 - 0.0014 18.7 0.8 0.0014 18.7 0.8 2.8 2 1 1 3 3 3 1 Laminin Domain II BLOC1_2 PF10046.9 KIY44373.1 - 0.0018 18.6 3.5 1.6 9.1 0.1 3.7 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.13 KIY44373.1 - 0.0034 17.1 3.2 0.0034 17.1 3.2 3.6 1 1 1 2 2 1 1 Protein of unknown function (DUF745) T3SSipB PF16535.5 KIY44373.1 - 0.012 16.1 5.5 0.012 16.1 5.5 4.4 1 1 3 4 4 3 0 Type III cell invasion protein SipB Sec34 PF04136.15 KIY44373.1 - 0.013 15.4 0.4 0.013 15.4 0.4 2.6 2 0 0 2 2 2 0 Sec34-like family ZapB PF06005.12 KIY44373.1 - 0.022 15.2 4.6 0.022 15.2 4.6 5.8 3 2 2 5 5 3 0 Cell division protein ZapB DUF948 PF06103.11 KIY44373.1 - 0.026 14.8 0.9 0.026 14.8 0.9 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PRKG1_interact PF15898.5 KIY44373.1 - 0.03 15.2 8.7 0.03 15.2 8.7 4.4 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 KIY44373.1 - 0.11 12.6 30.2 0.22 11.7 13.8 4.4 3 2 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 KIY44373.1 - 0.15 12.1 6.5 0.49 10.5 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KIY44373.1 - 0.16 12.7 19.0 3.6 8.3 0.0 4.9 2 1 3 5 5 5 0 Initiation control protein YabA Shugoshin_N PF07558.11 KIY44373.1 - 0.19 11.6 7.8 8.9 6.3 0.0 4.1 3 1 1 4 4 4 0 Shugoshin N-terminal coiled-coil region EzrA PF06160.12 KIY44373.1 - 0.73 7.9 10.6 0.076 11.2 3.9 2.2 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Tropomyosin PF00261.20 KIY44373.1 - 0.99 8.7 29.5 0.028 13.8 4.0 3.2 1 1 1 2 2 2 0 Tropomyosin TSC22 PF01166.18 KIY44373.1 - 2 8.8 0.0 2 8.8 0.0 3.8 3 1 1 4 4 3 0 TSC-22/dip/bun family HetR_C PF18460.1 KIY44373.1 - 4.8 7.2 10.9 4 7.4 2.8 3.1 1 1 2 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain p450 PF00067.22 KIY44375.1 - 4.8e-62 210.2 0.9 1e-59 202.5 0.9 2.0 1 1 0 1 1 1 1 Cytochrome P450 Dickkopf_N PF04706.12 KIY44376.1 - 0.003 18.0 7.1 0.003 18.0 7.1 4.4 4 0 0 4 4 4 2 Dickkopf N-terminal cysteine-rich region TRP PF06011.12 KIY44377.1 - 1.3e-75 254.8 32.3 1.8e-75 254.3 32.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KIY44377.1 - 9.3e-28 97.3 0.8 1.9e-27 96.3 0.8 1.6 1 0 0 1 1 1 1 ML-like domain Prominin PF05478.11 KIY44377.1 - 0.028 12.4 0.2 0.048 11.6 0.2 1.4 1 0 0 1 1 1 0 Prominin DUF4834 PF16118.5 KIY44377.1 - 0.092 13.7 2.4 29 5.7 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) F-box-like PF12937.7 KIY44378.1 - 1.4e-07 31.3 0.9 3.4e-07 30.1 0.9 1.7 1 0 0 1 1 1 1 F-box-like OSCP PF00213.18 KIY44379.1 - 9.9e-37 126.7 3.3 1.1e-26 94.0 1.1 2.0 2 0 0 2 2 2 2 ATP synthase delta (OSCP) subunit DUF4404 PF14357.6 KIY44379.1 - 0.18 12.5 0.7 5.6 7.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ICMT PF04140.14 KIY44380.1 - 4.8e-15 55.7 0.3 2e-14 53.8 0.1 1.9 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY44380.1 - 3.9e-13 49.7 0.5 6.6e-13 49.0 0.3 1.5 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIY44380.1 - 7.1e-05 21.7 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIY44380.1 - 0.08 12.4 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) MgsA_C PF12002.8 KIY44381.1 - 1.3e-52 178.2 0.1 1.9e-52 177.6 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KIY44381.1 - 4.4e-18 65.4 0.2 1e-17 64.2 0.2 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KIY44381.1 - 1.1e-15 58.3 0.0 8.5e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIY44381.1 - 2.3e-15 56.7 0.0 3.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIY44381.1 - 3.9e-07 30.6 0.9 0.00028 21.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KIY44381.1 - 7.9e-07 29.2 0.0 4.4e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KIY44381.1 - 6.5e-06 26.7 0.0 2.5e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KIY44381.1 - 2.4e-05 24.1 0.0 0.0025 17.5 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KIY44381.1 - 4.3e-05 23.8 0.3 0.0047 17.2 0.1 2.6 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KIY44381.1 - 5.2e-05 22.7 0.2 0.048 13.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KIY44381.1 - 0.00014 21.9 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KIY44381.1 - 0.00015 21.9 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 KIY44381.1 - 0.001 19.4 0.1 0.0018 18.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIY44381.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KIY44381.1 - 0.0025 18.0 0.0 0.0055 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIY44381.1 - 0.0031 17.9 0.0 0.0086 16.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.15 KIY44381.1 - 0.006 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain NB-ARC PF00931.22 KIY44381.1 - 0.008 15.4 0.0 0.21 10.7 0.0 2.2 1 1 1 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 KIY44381.1 - 0.011 16.3 0.0 0.022 15.2 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KIY44381.1 - 0.015 14.9 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 KIY44381.1 - 0.032 14.0 0.0 0.81 9.5 0.0 2.1 1 1 1 2 2 2 0 DNA polymerase III, delta subunit NACHT PF05729.12 KIY44381.1 - 0.045 13.7 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KIY44381.1 - 0.053 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KIY44381.1 - 0.066 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain RCS1 PF07326.11 KIY44381.1 - 0.068 13.1 0.5 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 SKI PF01202.22 KIY44381.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase IstB_IS21 PF01695.17 KIY44381.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 KIY44381.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KIY44381.1 - 0.15 12.0 0.2 3.1 7.6 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KIY44381.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KIY44381.1 - 0.17 11.9 0.1 25 4.8 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PPR_3 PF13812.6 KIY44382.1 - 2e-28 98.2 0.0 7.8e-07 29.1 0.0 5.7 4 2 3 7 7 7 7 Pentatricopeptide repeat domain PPR_2 PF13041.6 KIY44382.1 - 5e-23 81.0 0.0 3.6e-06 27.1 0.0 7.0 4 3 3 7 7 7 6 PPR repeat family PPR_long PF17177.4 KIY44382.1 - 1e-11 44.6 3.3 9.3e-06 25.2 0.7 4.0 2 2 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KIY44382.1 - 5.4e-08 32.4 1.5 0.62 9.8 0.0 6.2 9 0 0 9 9 9 3 PPR repeat PPR PF01535.20 KIY44382.1 - 6e-06 26.2 0.8 5.5 7.5 0.0 7.0 9 0 0 9 9 9 1 PPR repeat DUF3368 PF11848.8 KIY44382.1 - 0.0016 18.2 0.2 6.4 6.6 0.0 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3368) SecY PF00344.20 KIY44383.1 - 3e-72 243.5 10.9 3.7e-72 243.2 10.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KIY44383.1 - 3.7e-19 68.3 0.2 2.2e-18 65.8 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p DUF805 PF05656.14 KIY44383.1 - 5.8 7.4 8.2 0.77 10.2 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF805) UPF0020 PF01170.18 KIY44384.1 - 6.2e-09 35.8 0.1 6.7e-08 32.4 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KIY44384.1 - 0.0032 17.2 0.0 2 8.1 0.0 2.4 2 1 0 2 2 2 2 DNA methylase DUF43 PF01861.16 KIY44384.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain DUF1772 PF08592.11 KIY44385.1 - 7.9e-13 48.9 0.2 8.5e-13 48.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF5353 PF17304.2 KIY44385.1 - 0.053 13.3 0.2 0.081 12.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Glyco_hydro_18 PF00704.28 KIY44386.1 - 2.8e-57 194.8 5.6 3.6e-57 194.5 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Rad21_Rec8_N PF04825.13 KIY44387.1 - 2e-34 118.1 0.0 3.3e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KIY44387.1 - 1.9e-13 49.5 0.1 3.7e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Smr PF01713.21 KIY44388.1 - 0.062 13.7 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Smr domain MFS_1 PF07690.16 KIY44389.1 - 1.1e-13 50.8 28.3 1.1e-13 50.8 28.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KIY44389.1 - 1.2e-05 24.5 8.2 0.00011 21.3 0.3 2.4 2 0 0 2 2 2 2 Nucleoside H+ symporter DUF1129 PF06570.11 KIY44389.1 - 1.7 8.1 4.0 2 7.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Chitin_synth_1 PF01644.17 KIY44391.1 - 3.9e-74 248.0 0.1 6.7e-74 247.3 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KIY44391.1 - 2.5e-25 89.1 0.3 3.9e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KIY44391.1 - 3.6e-25 87.7 0.0 8.5e-25 86.5 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KIY44391.1 - 3.3e-06 27.2 10.8 1.5e-05 25.0 8.2 3.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 SWIM PF04434.17 KIY44392.1 - 1e-05 25.0 5.8 2.5e-05 23.8 5.8 1.7 1 1 0 1 1 1 1 SWIM zinc finger DUF1139 PF06599.11 KIY44392.1 - 0.19 11.1 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) zf-4CXXC_R1 PF10497.9 KIY44393.1 - 1.1e-12 48.0 20.5 1.8e-12 47.3 17.3 2.5 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Tim17 PF02466.19 KIY44394.1 - 4.6e-29 101.0 9.3 4.6e-29 101.0 9.3 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 KIY44394.1 - 0.31 11.2 8.6 0.46 10.6 3.1 2.6 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III DUF3180 PF11377.8 KIY44394.1 - 2.7 8.1 6.2 14 5.8 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) Rad9 PF04139.13 KIY44395.1 - 8.7e-35 120.4 0.0 1.8e-34 119.4 0.0 1.4 1 1 0 1 1 1 1 Rad9 ALIX_LYPXL_bnd PF13949.6 KIY44396.1 - 0.015 14.6 0.3 0.015 14.6 0.3 1.0 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV ATP-synt_DE_N PF02823.16 KIY44397.1 - 1.1e-16 60.5 0.1 1.6e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain GCS PF03074.16 KIY44398.1 - 4.9e-158 526.3 0.0 9.6e-158 525.3 0.0 1.5 1 1 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KIY44398.1 - 0.0028 17.0 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) APG6 PF04111.12 KIY44399.1 - 2.5e-68 229.6 0.0 4e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KIY44399.1 - 1.1e-27 97.2 25.6 1.1e-27 97.2 25.6 1.5 2 0 0 2 2 2 1 Apg6 coiled-coil region zf-P11 PF03854.14 KIY44399.1 - 0.14 11.8 1.1 0.27 10.9 1.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger HAUS6_N PF14661.6 KIY44399.1 - 0.44 10.1 7.9 0.69 9.5 7.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3179 PF11376.8 KIY44399.1 - 0.57 9.5 2.6 47 3.2 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3179) DUF724 PF05266.14 KIY44399.1 - 0.58 9.9 9.7 0.32 10.8 7.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KIY44399.1 - 1.1 9.4 14.3 1.7 8.7 14.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BBS1 PF14779.6 KIY44399.1 - 1.1 8.6 4.1 2 7.8 4.1 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 FapA PF03961.13 KIY44399.1 - 4.1 5.9 6.7 5.7 5.4 6.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ERM PF00769.19 KIY44399.1 - 4.6 7.0 24.8 1 9.1 21.4 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family RraA-like PF03737.15 KIY44401.1 - 1.5e-35 122.5 0.2 1.9e-35 122.2 0.2 1.1 1 0 0 1 1 1 1 Aldolase/RraA IMS PF00817.20 KIY44402.1 - 1e-41 142.4 0.0 2.4e-41 141.2 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KIY44402.1 - 1.4e-13 51.6 0.1 4.1e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KIY44402.1 - 8e-07 29.0 0.0 2.2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif RNF220 PF15926.5 KIY44402.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 TACC_C PF05010.14 KIY44402.1 - 0.028 14.2 2.8 0.25 11.1 0.4 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Terminase_2 PF03592.16 KIY44402.1 - 0.27 11.7 1.8 0.56 10.7 0.1 2.1 2 0 0 2 2 2 0 Terminase small subunit RabGAP-TBC PF00566.18 KIY44403.1 - 5.4e-52 176.6 0.0 6.7e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain p450 PF00067.22 KIY44404.1 - 6.6e-29 100.9 0.0 3.6e-12 45.8 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 DUF2162 PF09930.9 KIY44404.1 - 0.21 11.0 1.0 0.4 10.0 1.0 1.4 1 0 0 1 1 1 0 Predicted transporter (DUF2162) PTSIIA_gutA PF03829.13 KIY44405.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component Ion_trans PF00520.31 KIY44406.1 - 1.1e-105 352.3 81.2 1.2e-31 109.8 13.6 6.1 5 1 1 6 6 6 6 Ion transport protein Na_Ca_ex PF01699.24 KIY44407.1 - 7e-21 74.8 28.9 3.1e-16 59.7 12.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pex14_N PF04695.13 KIY44407.1 - 0.013 16.2 0.6 0.03 15.0 0.6 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRIMA1 PF16101.5 KIY44407.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 YtpI PF14007.6 KIY44407.1 - 0.8 9.9 4.1 2.4 8.4 1.8 2.8 1 1 1 2 2 2 0 YtpI-like protein Peptidase_C14 PF00656.22 KIY44408.1 - 1.7e-55 188.6 0.1 2.1e-55 188.4 0.1 1.0 1 0 0 1 1 1 1 Caspase domain GDA1_CD39 PF01150.17 KIY44409.1 - 4.3e-97 325.5 0.0 5.4e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family ETF PF01012.21 KIY44411.1 - 1.7e-36 125.8 3.1 3.2e-36 124.9 3.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KIY44411.1 - 1.1e-32 111.9 0.7 2.1e-32 111.0 0.7 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ILVD_EDD PF00920.21 KIY44412.1 - 9.7e-186 618.4 0.0 1.1e-185 618.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family SpoIIE PF07228.12 KIY44413.1 - 1e-07 32.1 0.0 4.9e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KIY44413.1 - 0.012 15.3 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C SKN1 PF03935.15 KIY44414.1 - 2.8e-29 101.9 0.4 3.7e-26 91.6 0.0 2.6 2 1 1 3 3 3 2 Beta-glucan synthesis-associated protein (SKN1) TPR_1 PF00515.28 KIY44415.1 - 1.5e-16 59.4 0.3 1.2e-05 24.9 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY44415.1 - 5.6e-16 57.3 1.0 9.1e-05 22.3 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44415.1 - 4.4e-11 43.2 2.8 3.5e-06 27.5 0.2 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY44415.1 - 2.3e-10 39.9 2.5 0.027 14.7 0.0 5.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44415.1 - 3.5e-10 39.8 8.8 0.016 16.0 0.0 6.2 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIY44415.1 - 1.9e-07 30.6 0.0 0.78 9.9 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44415.1 - 9.6e-06 26.0 1.3 0.0071 16.8 0.1 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44415.1 - 1.1e-05 25.6 3.1 0.017 15.4 0.4 3.9 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44415.1 - 1.3e-05 24.8 3.3 0.00054 19.6 0.0 4.0 2 1 3 5 5 5 1 TPR repeat TPR_17 PF13431.6 KIY44415.1 - 2.2e-05 24.5 0.5 0.94 10.0 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY44415.1 - 0.00044 20.4 0.3 0.1 12.8 0.0 2.8 2 1 1 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KIY44415.1 - 0.0017 18.1 0.0 0.007 16.1 0.0 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_6 PF13174.6 KIY44415.1 - 0.0028 18.2 0.2 14 6.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 KIY44415.1 - 0.0082 15.4 1.3 0.16 11.1 0.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY44415.1 - 0.037 14.2 3.3 0.39 10.9 0.0 3.1 3 1 1 4 4 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KIY44415.1 - 0.045 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 KIY44415.1 - 0.046 13.8 0.1 8.5 6.5 0.0 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KIY44415.1 - 0.047 13.6 5.6 2.3 8.2 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KIY44415.1 - 0.095 12.8 1.6 19 5.4 0.0 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF1641 PF07849.11 KIY44415.1 - 0.16 11.8 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) ATP_transf PF09830.9 KIY44416.1 - 2.4e-22 78.8 0.0 3.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 KIY44416.1 - 0.032 14.0 0.2 0.18 11.6 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4922) HIT PF01230.23 KIY44416.1 - 0.095 13.5 0.1 0.63 10.8 0.0 2.2 2 0 0 2 2 2 0 HIT domain Helicase_RecD PF05127.14 KIY44416.1 - 0.19 11.6 0.0 0.59 10.0 0.0 1.7 2 0 0 2 2 2 0 Helicase HicA_toxin PF07927.12 KIY44417.1 - 1.3e-05 25.1 0.0 3.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Gti1_Pac2 PF09729.9 KIY44419.1 - 5.9e-27 94.9 0.2 7.7e-24 84.8 0.4 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Tubulin_3 PF14881.6 KIY44420.1 - 1.1e-25 90.4 0.0 1.9e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KIY44420.1 - 9.9e-22 77.5 0.0 1.7e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KIY44420.1 - 1.9e-05 25.0 0.0 0.0051 17.0 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain TIG PF01833.24 KIY44422.1 - 9.7e-11 41.6 1.0 6.7e-10 38.9 0.5 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 KIY44422.1 - 3.1e-09 36.9 1.2 2.7e-06 27.6 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY44422.1 - 1.2e-07 31.8 0.3 0.017 15.5 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KIY44422.1 - 2.5e-07 31.2 0.0 1e-06 29.2 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY44422.1 - 0.00011 22.7 0.1 0.0086 16.6 0.2 3.1 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY44422.1 - 0.0025 18.2 0.1 1.2 9.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat VanZ PF04892.12 KIY44424.1 - 0.00011 22.8 5.8 0.00019 22.1 5.8 1.3 1 1 0 1 1 1 1 VanZ like family Virul_fac_BrkB PF03631.15 KIY44424.1 - 0.064 12.9 5.0 0.093 12.3 5.0 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF1129 PF06570.11 KIY44424.1 - 0.088 12.3 2.7 0.13 11.7 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2070 PF09843.9 KIY44424.1 - 1.1 7.5 2.5 1.4 7.1 2.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NUC173 PF08161.12 KIY44425.1 - 2.6e-56 190.5 0.5 1.7e-54 184.6 0.2 3.3 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.22 KIY44425.1 - 0.0048 17.0 0.5 0.34 11.3 0.1 3.4 2 0 0 2 2 2 1 HEAT repeat MMS19_C PF12460.8 KIY44425.1 - 0.23 10.5 0.0 0.23 10.5 0.0 4.8 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal PAC2 PF09754.9 KIY44426.1 - 7.9e-20 71.8 0.0 1e-19 71.4 0.0 1.1 1 0 0 1 1 1 1 PAC2 family DUF3890 PF13029.6 KIY44426.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) SEO_C PF14577.6 KIY44426.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Acyltransferase PF01553.21 KIY44427.1 - 7.4e-11 41.8 0.0 2e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase ABC2_membrane PF01061.24 KIY44427.1 - 0.36 10.2 10.3 2.9 7.3 8.3 2.1 2 0 0 2 2 2 0 ABC-2 type transporter ABC_tran PF00005.27 KIY44429.1 - 2.6e-48 164.0 0.0 5.1e-29 101.5 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIY44429.1 - 1.8e-15 57.5 0.0 3e-06 27.3 0.0 4.2 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY44429.1 - 8.3e-13 48.3 0.0 4e-05 23.2 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KIY44429.1 - 1.2e-10 41.2 0.1 2.3e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KIY44429.1 - 8.6e-08 32.9 0.0 0.00086 19.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KIY44429.1 - 1.1e-06 28.7 0.5 0.021 14.9 0.0 3.7 3 1 0 3 3 3 2 50S ribosome-binding GTPase HEAT PF02985.22 KIY44429.1 - 3.8e-06 26.7 2.3 1.4 9.3 0.1 4.6 3 0 0 3 3 3 1 HEAT repeat AAA_29 PF13555.6 KIY44429.1 - 1.1e-05 25.0 2.2 0.11 12.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY44429.1 - 0.00011 22.5 0.2 0.38 11.0 0.0 3.2 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 KIY44429.1 - 0.00013 22.2 0.4 0.46 10.5 0.0 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_16 PF13191.6 KIY44429.1 - 0.00013 22.4 0.1 0.85 10.0 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY44429.1 - 0.00014 21.8 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KIY44429.1 - 0.00016 22.2 0.0 0.34 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIY44429.1 - 0.00031 21.0 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMS19_C PF12460.8 KIY44429.1 - 0.0004 19.6 0.4 0.052 12.7 0.3 2.9 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal NACHT PF05729.12 KIY44429.1 - 0.00082 19.3 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KIY44429.1 - 0.00092 19.4 0.0 0.5 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain Tudor-knot PF11717.8 KIY44429.1 - 0.0014 18.4 0.3 0.0031 17.4 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MeaB PF03308.16 KIY44429.1 - 0.0023 16.9 0.8 1.2 8.1 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Adaptin_N PF01602.20 KIY44429.1 - 0.0026 16.4 0.7 0.16 10.5 1.4 2.1 1 1 0 2 2 2 1 Adaptin N terminal region NB-ARC PF00931.22 KIY44429.1 - 0.0037 16.5 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 KIY44429.1 - 0.004 16.9 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY44429.1 - 0.0071 16.1 0.0 2.8 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain HEAT_EZ PF13513.6 KIY44429.1 - 0.0076 16.7 3.5 0.091 13.3 0.2 3.5 4 0 0 4 4 2 1 HEAT-like repeat AAA_13 PF13166.6 KIY44429.1 - 0.0092 14.7 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIY44429.1 - 0.013 15.9 0.1 5.3 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KIY44429.1 - 0.027 14.7 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KIY44429.1 - 0.032 13.9 0.1 3.4 7.3 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain IFRD PF05004.13 KIY44429.1 - 0.038 13.1 0.2 0.067 12.3 0.2 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) AAA_14 PF13173.6 KIY44429.1 - 0.04 13.9 0.1 12 5.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIY44429.1 - 0.047 13.5 0.3 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_27 PF13514.6 KIY44429.1 - 0.056 13.0 0.0 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIY44429.1 - 0.059 12.9 0.1 7.5 6.1 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CLASP_N PF12348.8 KIY44429.1 - 0.071 12.7 0.0 9.5 5.7 0.1 2.5 2 0 0 2 2 2 0 CLASP N terminal DUF3584 PF12128.8 KIY44429.1 - 0.09 10.3 1.7 3.8 4.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_7 PF12775.7 KIY44429.1 - 0.094 12.2 0.0 3.4 7.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIY44429.1 - 0.11 11.7 0.1 2.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 KIY44429.1 - 0.14 12.2 0.1 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KIY44429.1 - 0.19 10.9 0.0 0.71 9.0 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 KIY44429.1 - 0.19 12.2 0.0 2.7 8.4 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arm PF00514.23 KIY44429.1 - 0.55 10.4 2.0 4.1 7.6 0.2 3.3 3 0 0 3 3 2 0 Armadillo/beta-catenin-like repeat ABC_tran_Xtn PF12848.7 KIY44429.1 - 1 9.4 3.4 0.39 10.8 0.2 1.9 2 0 0 2 2 1 0 ABC transporter Homeodomain PF00046.29 KIY44430.1 - 7.4e-17 60.9 3.0 1.5e-16 59.9 3.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIY44430.1 - 0.0028 17.5 0.3 0.0067 16.3 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KIY44430.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Pkinase PF00069.25 KIY44431.1 - 3e-52 177.6 0.0 6.2e-38 130.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44431.1 - 5e-22 78.4 0.0 8.7e-16 58.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY44431.1 - 7.6e-05 22.2 0.2 0.0013 18.1 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KIY44431.1 - 0.00054 19.0 0.0 0.00081 18.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY44431.1 - 0.0041 17.1 0.4 0.013 15.5 0.4 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C2H2 PF00096.26 KIY44432.1 - 6.5e-15 54.7 5.1 7.2e-07 29.3 0.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY44432.1 - 4.9e-12 45.6 4.8 3.1e-05 24.4 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY44432.1 - 2.9e-09 36.9 13.2 9.5e-06 25.8 0.1 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.7 KIY44432.1 - 1.4e-05 25.3 2.1 7.7e-05 22.9 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY44432.1 - 9e-05 22.6 0.9 0.00043 20.5 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIY44432.1 - 0.00055 20.2 0.2 0.00064 20.0 0.2 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KIY44432.1 - 0.0014 18.6 3.8 0.67 10.0 1.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KIY44432.1 - 0.0019 18.3 0.4 0.45 10.7 0.2 2.2 1 1 1 2 2 2 2 Zinc ribbon domain zf-BED PF02892.15 KIY44432.1 - 0.0042 17.1 2.5 0.2 11.7 0.3 2.2 2 0 0 2 2 2 1 BED zinc finger zf-C2HC_2 PF13913.6 KIY44432.1 - 0.0064 16.4 7.6 0.015 15.1 0.3 2.5 2 1 0 2 2 2 1 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KIY44432.1 - 0.0072 16.1 13.5 0.02 14.6 1.9 3.1 3 0 0 3 3 3 1 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 KIY44432.1 - 0.011 15.6 0.6 0.4 10.6 0.1 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 KIY44432.1 - 0.013 15.2 7.2 0.29 10.9 0.6 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KIY44432.1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.3 1 1 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 KIY44432.1 - 0.032 14.6 0.3 2.9 8.3 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KIY44432.1 - 0.056 13.2 0.1 0.078 12.8 0.1 1.3 1 0 0 1 1 1 0 GAGA factor DUF3268 PF11672.8 KIY44432.1 - 0.078 13.3 0.1 0.08 13.3 0.1 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2H2_3rep PF18868.1 KIY44432.1 - 0.23 12.1 2.5 1.7 9.4 0.1 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2HC_14 PF18574.1 KIY44432.1 - 0.69 9.8 3.3 0.78 9.6 0.3 2.3 2 0 0 2 2 2 0 C2HC Zing finger domain BolA PF01722.18 KIY44433.1 - 7.4e-25 87.0 0.6 9.4e-25 86.7 0.6 1.1 1 0 0 1 1 1 1 BolA-like protein CENP_C_N PF15622.6 KIY44434.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal PITH PF06201.13 KIY44435.1 - 3.1e-20 72.9 0.0 3.8e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain SelP_N PF04592.14 KIY44435.1 - 5.4 6.4 11.8 12 5.2 11.8 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UBX PF00789.20 KIY44436.1 - 5.9e-13 48.8 0.2 9.3e-13 48.2 0.2 1.3 1 0 0 1 1 1 1 UBX domain DUF4685 PF15737.5 KIY44436.1 - 0.063 13.7 0.8 3.5 8.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4685) zf-C2H2 PF00096.26 KIY44437.1 - 1.5e-12 47.2 7.9 1.4e-05 25.3 3.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY44437.1 - 4.9e-10 39.4 7.1 2e-07 31.1 0.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY44437.1 - 3.6e-08 33.6 6.3 0.0002 21.9 1.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KIY44437.1 - 1.1e-05 25.7 0.8 0.009 16.4 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIY44437.1 - 1.9e-05 24.5 2.9 0.0071 16.3 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY44437.1 - 0.00026 21.2 6.6 0.0013 19.0 0.3 2.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KIY44437.1 - 0.0025 17.6 2.2 1.3 8.8 0.0 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-LYAR PF08790.11 KIY44437.1 - 0.069 13.1 2.2 7.8 6.5 0.0 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Ta0938 PF11494.8 KIY44437.1 - 0.097 13.0 1.2 2.3 8.5 0.0 2.0 1 1 1 2 2 2 0 Ta0938 BolA PF01722.18 KIY44437.1 - 0.1 12.9 0.1 0.37 11.1 0.0 1.8 2 0 0 2 2 2 0 BolA-like protein zf_C2H2_ZHX PF18387.1 KIY44437.1 - 0.19 11.4 2.1 1.1 8.9 1.3 1.9 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Acetyltransf_1 PF00583.25 KIY44438.1 - 2.2e-11 44.0 0.0 3.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY44438.1 - 4.9e-09 36.5 0.1 6.8e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY44438.1 - 1.5e-08 34.7 0.1 2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY44438.1 - 3e-05 23.9 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KIY44438.1 - 0.00064 19.9 0.0 0.00082 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KIY44438.1 - 0.0075 15.8 0.3 0.0085 15.6 0.3 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 KIY44438.1 - 0.017 15.8 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lipid_bd PF12888.7 KIY44438.1 - 0.09 13.2 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-binding putative hydrolase Acetyltransf_8 PF13523.6 KIY44438.1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KIY44439.1 - 2.2e-62 210.8 0.0 2.5e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44439.1 - 1.3e-37 129.5 0.0 1.6e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY44439.1 - 0.00014 20.8 0.0 0.00024 20.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY44439.1 - 0.00022 20.6 0.0 0.001 18.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KIY44439.1 - 0.035 13.1 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KIY44439.1 - 0.063 12.6 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GPI-anchored PF10342.9 KIY44441.1 - 0.0062 17.3 0.0 0.008 16.9 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cyclin PF08613.11 KIY44443.1 - 0.00036 20.9 0.0 0.0011 19.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KIY44443.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain PKcGMP_CC PF16808.5 KIY44444.1 - 0.0045 16.8 0.7 0.0085 15.9 0.7 1.4 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_2 PF07716.15 KIY44444.1 - 0.017 15.2 8.8 0.028 14.5 8.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF641 PF04859.12 KIY44444.1 - 0.024 15.0 1.0 0.047 14.0 1.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 KIY44444.1 - 0.032 14.3 6.4 0.054 13.6 6.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor SLT PF01464.20 KIY44445.1 - 7.1e-13 48.3 0.0 1.1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 KIY44445.1 - 0.00068 19.4 0.7 0.0016 18.1 0.7 1.6 1 1 0 1 1 1 1 Lysozyme-like PPP5 PF08321.12 KIY44446.1 - 4.4e-30 103.8 0.0 7.9e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KIY44446.1 - 8.5e-25 88.4 0.2 1.5e-24 87.6 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KIY44446.1 - 2.1e-12 46.3 7.6 5.6e-07 29.1 0.3 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY44446.1 - 4.1e-10 39.0 8.1 0.00024 21.0 0.2 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44446.1 - 1.7e-07 30.8 1.1 0.036 13.8 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 KIY44446.1 - 4.9e-07 30.2 1.3 0.99 10.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44446.1 - 1.2e-06 29.0 2.9 0.024 15.3 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44446.1 - 8.6e-06 26.2 2.2 0.04 14.8 0.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY44446.1 - 3.8e-05 23.8 0.2 0.086 13.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY44446.1 - 6.6e-05 23.0 0.1 0.00022 21.3 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY44446.1 - 0.00081 19.9 1.5 0.42 11.3 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY44446.1 - 0.0028 17.7 2.2 0.042 14.1 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44446.1 - 0.11 12.8 2.0 6.1 7.2 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Slu7 PF11708.8 KIY44447.1 - 1.2e-108 362.9 13.0 1.2e-108 362.9 13.0 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KIY44447.1 - 0.14 11.9 0.3 0.27 11.0 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle ATP-sulfurylase PF01747.17 KIY44448.1 - 1.8e-87 292.3 0.2 2.9e-87 291.6 0.2 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KIY44448.1 - 5.2e-53 179.0 0.0 8.8e-53 178.2 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 KIY44448.1 - 3.2e-34 118.1 0.0 4.8e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase bPH_6 PF10756.9 KIY44448.1 - 0.12 12.4 1.8 0.16 12.1 0.4 2.0 2 0 0 2 2 2 0 Bacterial PH domain ERO1 PF04137.15 KIY44450.1 - 1.3e-117 393.0 0.1 1.5e-117 392.8 0.1 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) COG7 PF10191.9 KIY44451.1 - 2.9e-77 260.6 1.1 1.7e-46 158.9 1.5 3.3 3 1 0 3 3 3 3 Golgi complex component 7 (COG7) AOX PF01786.17 KIY44451.1 - 0.072 12.7 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Alternative oxidase zf-SNAP50_C PF12251.8 KIY44452.1 - 6.8e-28 97.7 0.0 1.1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF1569 PF07606.11 KIY44452.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) Pyr_redox_2 PF07992.14 KIY44453.1 - 2e-17 63.4 0.0 2.4e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY44453.1 - 6.2e-08 33.1 0.0 1.2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.22 KIY44454.1 - 1.6e-11 43.9 0.0 2.1e-08 33.8 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 KIY44454.1 - 6.3e-09 35.7 0.6 1.6e-08 34.4 0.6 1.7 1 0 0 1 1 1 1 Surp module TonB_N PF16031.5 KIY44454.1 - 0.0016 19.0 0.9 0.0038 17.7 0.9 1.6 1 0 0 1 1 1 1 TonB polyproline region CTD_bind PF04818.13 KIY44454.1 - 0.0073 17.1 0.0 0.026 15.4 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 KIY44454.1 - 0.033 14.3 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif DUF447 PF04289.12 KIY44454.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF447) ATP-sulfurylase PF01747.17 KIY44455.1 - 1.9e-86 288.9 0.4 2.9e-86 288.3 0.4 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KIY44455.1 - 6.1e-52 175.5 0.0 1.1e-51 174.7 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 KIY44455.1 - 2.1e-41 141.4 0.0 3.2e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Vps51 PF08700.11 KIY44456.1 - 3.1e-24 84.9 1.5 4.5e-24 84.3 1.5 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KIY44456.1 - 0.00085 19.5 1.5 0.00085 19.5 1.5 1.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KIY44456.1 - 0.0015 17.3 0.8 0.0019 16.9 0.8 1.1 1 0 0 1 1 1 1 Dor1-like family FlgN PF05130.12 KIY44456.1 - 0.028 14.9 1.6 0.041 14.4 1.6 1.2 1 0 0 1 1 1 0 FlgN protein KH_1 PF00013.29 KIY44457.1 - 2.5e-84 277.1 31.5 7.4e-11 41.7 0.0 13.8 14 1 0 14 14 14 10 KH domain KH_2 PF07650.17 KIY44457.1 - 1.4e-09 37.6 12.9 1.4 8.8 0.7 7.5 7 0 0 7 7 7 5 KH domain SLS PF14611.6 KIY44457.1 - 7.8e-06 25.9 24.8 0.067 13.0 0.2 8.4 6 3 3 10 10 10 4 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 KIY44457.1 - 5.7e-05 22.9 8.6 3.8 7.5 0.1 7.4 7 1 1 8 8 8 1 KH domain KH_5 PF13184.6 KIY44457.1 - 1.1 9.3 14.6 4.6 7.4 0.2 5.2 5 0 0 5 5 5 0 NusA-like KH domain SMC_N PF02463.19 KIY44458.1 - 4.9e-63 212.5 1.7 1.4e-62 211.0 1.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIY44458.1 - 1.1e-22 80.6 0.1 3.7e-22 78.8 0.1 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIY44458.1 - 2e-12 47.5 4.8 2.2e-05 24.5 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIY44458.1 - 1.8e-05 25.3 40.5 1.8e-05 25.3 40.5 7.0 2 2 2 5 5 5 1 AAA domain AAA_29 PF13555.6 KIY44458.1 - 5.7e-05 22.8 0.2 0.00023 20.8 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIY44458.1 - 0.032 14.7 0.1 0.032 14.7 0.1 6.6 3 2 0 3 3 3 0 ABC transporter COG2 PF06148.11 KIY44458.1 - 0.097 12.8 0.2 0.097 12.8 0.2 8.4 6 2 3 9 9 9 0 COG (conserved oligomeric Golgi) complex component, COG2 DEAD_2 PF06733.15 KIY44459.1 - 2.7e-49 167.2 0.0 5.7e-49 166.1 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KIY44459.1 - 1.3e-45 155.4 1.8 4.4e-40 137.4 0.3 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KIY44459.1 - 8.6e-44 149.7 0.0 1.7e-43 148.7 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KIY44459.1 - 0.00024 21.1 0.1 0.018 15.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY44459.1 - 0.0061 16.3 0.1 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF2075 PF09848.9 KIY44459.1 - 0.0088 15.3 0.1 3.6 6.7 0.1 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) FliT PF05400.13 KIY44459.1 - 0.13 13.1 2.0 2.2 9.2 0.1 2.9 2 0 0 2 2 2 0 Flagellar protein FliT RNase_H2-Ydr279 PF09468.10 KIY44460.1 - 5.2e-18 65.7 0.0 8e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KIY44460.1 - 1.2e-12 47.9 0.0 3.3e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain MmgE_PrpD PF03972.14 KIY44462.1 - 1.4e-155 518.2 0.0 1.7e-155 517.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Fungal_trans PF04082.18 KIY44463.1 - 1.6e-26 92.9 0.4 1.6e-26 92.9 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY44463.1 - 0.0039 17.3 5.6 0.0039 17.3 5.6 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KIY44463.1 - 0.023 14.8 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Sugar_tr PF00083.24 KIY44464.1 - 4.3e-33 114.9 22.4 4.2e-24 85.2 7.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIY44464.1 - 1.7e-31 109.5 35.5 2.4e-31 108.9 35.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY44464.1 - 0.041 12.8 8.0 3.7 6.3 8.0 2.8 1 1 0 1 1 1 0 MFS_1 like family MMR_HSR1 PF01926.23 KIY44465.1 - 1.1e-16 60.9 0.2 4e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY44465.1 - 1.1e-07 31.9 0.0 3.4e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KIY44465.1 - 3e-07 30.1 0.0 6.3e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KIY44465.1 - 0.00078 19.0 0.0 0.054 13.0 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIY44465.1 - 0.002 18.2 0.4 0.35 10.9 0.1 2.8 2 1 1 3 3 3 1 Dynamin family MeaB PF03308.16 KIY44465.1 - 0.0054 15.7 0.1 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KIY44465.1 - 0.0074 16.7 0.6 0.51 10.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 KIY44465.1 - 0.031 13.9 0.2 0.67 9.5 0.0 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KIY44465.1 - 0.069 13.4 0.0 4.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KIY44465.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 KIY44465.1 - 0.16 11.3 0.1 0.37 10.1 0.1 1.6 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 KIY44465.1 - 0.18 12.4 0.3 0.61 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1771 PF08590.10 KIY44466.1 - 0.00018 21.8 5.1 0.00047 20.5 5.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Atrophin-1 PF03154.15 KIY44466.1 - 0.0067 14.8 10.4 0.0092 14.3 10.4 1.2 1 0 0 1 1 1 1 Atrophin-1 family Phage_Gp23 PF10669.9 KIY44466.1 - 0.012 15.9 1.0 0.012 15.9 1.0 1.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF3915 PF13054.6 KIY44466.1 - 0.021 14.8 8.5 0.021 14.8 8.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3915) DUF2749 PF10907.8 KIY44466.1 - 0.14 12.4 0.2 0.93 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) SieB PF14163.6 KIY44466.1 - 0.21 11.1 1.4 0.73 9.3 1.4 1.8 1 1 0 1 1 1 0 Super-infection exclusion protein B SNF2_N PF00176.23 KIY44467.1 - 8.3e-58 195.8 0.3 1.4e-57 195.0 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 KIY44467.1 - 6.8e-24 84.1 0.6 6.8e-24 84.1 0.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 KIY44467.1 - 5.3e-21 74.3 4.1 1.5e-14 53.6 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KIY44467.1 - 7.3e-20 71.4 0.0 2.2e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KIY44467.1 - 4.5e-11 42.4 0.6 1.1e-10 41.2 0.6 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KIY44467.1 - 1.5e-08 34.8 0.0 5.5e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KIY44467.1 - 4.4e-08 33.5 0.7 4.4e-08 33.5 0.7 3.9 2 1 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 KIY44467.1 - 2e-05 25.1 1.7 8.9e-05 23.1 0.4 2.8 3 0 0 3 3 2 1 CDH1/2 SANT-Helical linker 1 FlhC PF05280.11 KIY44467.1 - 0.0062 16.3 0.7 0.029 14.1 0.2 2.2 2 0 0 2 2 2 1 Flagellar transcriptional activator (FlhC) Methyltransf_18 PF12847.7 KIY44467.1 - 0.01 15.8 0.0 0.03 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Asparaginase_C PF17763.1 KIY44467.1 - 0.032 14.5 0.0 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain AAA_22 PF13401.6 KIY44467.1 - 0.09 13.0 0.5 0.85 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain FKBP_N PF01346.18 KIY44467.1 - 8 7.5 8.5 3.6 8.6 3.1 3.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Pil1 PF13805.6 KIY44470.1 - 2.5e-14 53.4 0.0 3e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 LRR_11 PF18831.1 KIY44470.1 - 0.099 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Tfb4 PF03850.14 KIY44472.1 - 1.5e-80 270.7 0.0 1.7e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Asparaginase_2 PF01112.18 KIY44473.1 - 6.3e-47 160.1 3.3 9.5e-47 159.5 3.3 1.2 1 0 0 1 1 1 1 Asparaginase zf-U1 PF06220.12 KIY44474.1 - 5.8e-11 42.0 0.8 9.3e-11 41.3 0.8 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2 PF00096.26 KIY44475.1 - 5.4e-10 39.2 14.3 0.00059 20.1 1.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY44475.1 - 3.4e-06 27.2 11.5 0.00013 22.3 0.2 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY44475.1 - 8e-05 23.2 12.9 0.12 13.2 0.7 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KIY44475.1 - 0.0013 19.3 6.3 0.25 12.0 3.8 2.3 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 KIY44475.1 - 0.0025 18.1 2.5 0.053 13.9 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KIY44475.1 - 0.019 15.7 2.5 0.087 13.5 0.3 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-LYAR PF08790.11 KIY44475.1 - 0.2 11.6 9.0 0.6 10.1 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zinc_ribbon_9 PF14369.6 KIY44475.1 - 1.1 9.5 9.2 0.29 11.4 0.7 2.9 3 0 0 3 3 3 0 zinc-ribbon SCO1-SenC PF02630.14 KIY44476.1 - 2e-44 150.7 0.0 3e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KIY44476.1 - 0.0012 18.8 0.1 0.0054 16.6 0.1 2.1 1 1 0 1 1 1 1 AhpC/TSA family Ribosomal_S9 PF00380.19 KIY44477.1 - 3.5e-44 150.2 0.1 7.1e-44 149.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S9/S16 CitMHS PF03600.16 KIY44478.1 - 9.1e-09 34.9 40.6 2.8e-08 33.3 25.7 2.6 1 1 1 2 2 2 2 Citrate transporter ArsB PF02040.15 KIY44478.1 - 7.9e-06 25.5 15.7 8.1e-06 25.4 8.3 2.5 2 1 0 2 2 2 2 Arsenical pump membrane protein TPR_1 PF00515.28 KIY44479.1 - 2.3e-17 62.0 5.5 3.2e-05 23.5 1.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIY44479.1 - 8e-15 53.7 10.1 0.0027 17.7 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY44479.1 - 3.1e-13 48.8 3.5 0.0033 17.5 0.4 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44479.1 - 6.6e-11 41.7 3.8 0.0018 17.9 1.5 4.6 3 1 1 4 4 4 3 TPR repeat TPR_17 PF13431.6 KIY44479.1 - 2.6e-09 36.8 5.5 0.063 13.7 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44479.1 - 9e-09 35.4 17.8 0.016 16.0 0.2 7.2 6 1 2 8 8 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44479.1 - 3.8e-07 30.3 9.2 0.00024 21.3 3.5 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY44479.1 - 2.3e-06 27.7 6.3 0.012 15.7 0.5 4.2 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44479.1 - 7.1e-06 26.6 17.3 0.016 15.8 1.7 5.5 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 KIY44479.1 - 1.9e-05 24.9 10.0 0.01 16.2 0.3 5.2 3 3 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44479.1 - 6.3e-05 23.4 21.2 0.016 15.7 1.0 5.8 5 2 2 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY44479.1 - 0.0083 16.3 4.6 0.068 13.4 0.9 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KIY44479.1 - 0.059 13.4 5.2 16 5.8 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY44479.1 - 1.2 9.1 13.1 0.51 10.3 1.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KIY44479.1 - 2.7 7.0 9.7 0.41 9.7 0.1 2.7 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference ANAPC_CDC26 PF10471.9 KIY44480.1 - 0.12 13.2 2.2 0.27 12.1 2.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 PRA1 PF03208.19 KIY44481.1 - 2.9e-31 108.0 0.7 3.7e-31 107.7 0.7 1.0 1 0 0 1 1 1 1 PRA1 family protein YwiC PF14256.6 KIY44481.1 - 0.037 14.3 5.4 0.091 13.1 0.3 2.1 2 0 0 2 2 2 0 YwiC-like protein PAS PF00989.25 KIY44482.1 - 0.00044 20.2 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KIY44482.1 - 0.0012 19.0 14.7 0.0022 18.1 14.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T4SS_TraI PF16932.5 KIY44482.1 - 0.099 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer Allantoicase PF03561.15 KIY44484.1 - 1e-90 301.2 0.0 3e-47 160.2 0.1 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 KIY44484.1 - 1.3e-38 132.6 0.0 2.1e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase Thr_synth_N PF14821.6 KIY44485.1 - 9.3e-25 86.7 0.0 2.6e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KIY44485.1 - 1.6e-17 63.9 0.0 3.3e-17 62.8 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mito_carr PF00153.27 KIY44486.1 - 2.1e-70 232.7 6.8 4.9e-24 84.1 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIY44486.1 - 0.002 17.3 0.2 2.1 7.4 0.0 3.2 2 1 0 3 3 3 2 Gammaproteobacterial serine protease RhoGAP PF00620.27 KIY44487.1 - 1.9e-29 102.5 0.0 3.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Ntox28 PF15605.6 KIY44488.1 - 0.022 15.0 0.4 0.055 13.7 0.4 1.6 1 0 0 1 1 1 0 Bacterial toxin 28 NAD_binding_5 PF07994.12 KIY44488.1 - 0.044 13.2 0.2 7.7 5.8 0.1 2.2 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase HSBP1 PF06825.12 KIY44488.1 - 0.094 12.6 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DEK_C PF08766.11 KIY44491.1 - 3 7.8 6.5 0.28 11.1 0.5 2.5 3 1 0 3 3 3 0 DEK C terminal domain DUF935 PF06074.12 KIY44491.1 - 3.1 6.4 13.7 0.018 13.8 3.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF935) CDC27 PF09507.10 KIY44491.1 - 9.8 5.4 41.7 0.15 11.5 29.8 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 bZIP_1 PF00170.21 KIY44494.1 - 5.2e-08 32.9 8.8 5.2e-08 32.9 8.8 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KIY44494.1 - 6.9e-07 29.3 8.9 6.9e-07 29.3 8.9 2.5 2 0 0 2 2 2 1 Basic region leucine zipper CENP-F_N PF10481.9 KIY44494.1 - 0.00064 19.5 0.6 0.0012 18.6 0.6 1.3 1 0 0 1 1 1 1 Cenp-F N-terminal domain ABC_tran_CTD PF16326.5 KIY44494.1 - 0.0015 18.7 7.1 0.0096 16.1 8.2 1.8 2 0 0 2 2 2 1 ABC transporter C-terminal domain FapA PF03961.13 KIY44494.1 - 0.31 9.6 1.1 0.45 9.1 1.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KIY44494.1 - 0.33 10.8 8.7 0.13 12.0 1.5 2.4 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.18 KIY44494.1 - 0.42 10.9 1.8 16 5.8 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Lzipper-MIP1 PF14389.6 KIY44494.1 - 0.92 9.9 5.0 0.75 10.1 0.6 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ATG16 PF08614.11 KIY44494.1 - 4 7.6 15.6 0.5 10.6 10.8 1.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 KIY44494.1 - 5 7.4 9.1 22 5.4 9.1 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_Maf PF03131.17 KIY44494.1 - 5.2 7.7 8.3 1.6 9.3 2.4 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor MFS_1 PF07690.16 KIY44495.1 - 6.3e-32 110.9 35.4 8.2e-32 110.5 35.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4267 PF14087.6 KIY44495.1 - 0.78 9.8 10.0 0.14 12.2 5.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4267) CTP_transf_like PF01467.26 KIY44496.1 - 3.1e-24 85.8 0.0 3.9e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Acyl-CoA_dh_N PF02771.16 KIY44497.1 - 1.9e-22 80.0 0.0 3.7e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KIY44497.1 - 7.6e-22 78.1 0.0 1.2e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIY44497.1 - 1.4e-20 73.3 0.0 2.4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain WD40 PF00400.32 KIY44498.1 - 9.2e-45 149.7 25.2 1.2e-08 35.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY44498.1 - 2.3e-10 40.6 0.9 0.12 12.7 0.0 4.9 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY44498.1 - 0.0002 20.2 6.7 0.032 12.9 0.2 4.2 4 1 1 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.12 KIY44498.1 - 0.00064 19.6 0.6 3.2 7.8 0.0 4.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 KIY44498.1 - 0.0028 16.8 0.0 0.23 10.5 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 KIY44498.1 - 0.028 12.9 0.1 1.5 7.3 0.2 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF1416 PF07210.12 KIY44498.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) SLAC1 PF03595.17 KIY44499.1 - 3.4e-74 250.0 55.7 3.8e-74 249.8 55.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Inhibitor_I9 PF05922.16 KIY44500.1 - 0.14 12.9 0.0 0.31 11.7 0.0 1.7 1 1 0 1 1 1 0 Peptidase inhibitor I9 Ribonuclease_3 PF00636.26 KIY44501.1 - 7.1e-36 123.0 0.0 1.3e-17 64.3 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIY44501.1 - 7.7e-22 77.8 0.4 1.1e-10 41.8 0.0 4.3 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KIY44501.1 - 5.5e-21 74.5 0.2 2.3e-20 72.5 0.0 2.2 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.31 KIY44501.1 - 2.5e-16 60.0 0.0 7.1e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY44501.1 - 2e-14 53.8 0.0 3.9e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY44501.1 - 3.1e-14 53.4 0.0 7.2e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HhH-GPD PF00730.25 KIY44502.1 - 1.3e-08 35.2 0.0 3.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Oxidored_q6 PF01058.22 KIY44504.1 - 3.2e-22 78.8 0.1 4.6e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NUC202 PF08166.12 KIY44504.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 NUC202 domain DUF3450 PF11932.8 KIY44505.1 - 0.0052 16.1 3.2 0.0088 15.4 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF812 PF05667.11 KIY44505.1 - 0.042 12.8 0.8 0.063 12.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1501 PF07394.12 KIY44505.1 - 0.042 12.9 4.0 0.068 12.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DASH_Hsk3 PF08227.11 KIY44505.1 - 0.051 13.9 1.5 0.11 12.8 1.5 1.6 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Ribosomal_S11 PF00411.19 KIY44505.1 - 0.07 13.5 0.1 0.3 11.5 0.1 2.1 1 0 0 1 1 1 0 Ribosomal protein S11 PRKG1_interact PF15898.5 KIY44505.1 - 0.074 14.0 8.8 0.21 12.5 8.8 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Uso1_p115_C PF04871.13 KIY44505.1 - 0.078 13.4 8.8 0.15 12.4 8.8 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TolA_bind_tri PF16331.5 KIY44505.1 - 0.097 12.8 3.8 0.21 11.7 3.5 1.8 1 1 0 1 1 1 0 TolA binding protein trimerisation ATG16 PF08614.11 KIY44505.1 - 0.13 12.5 12.3 0.9 9.7 12.1 2.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.15 KIY44505.1 - 0.24 11.5 4.7 7.1 6.8 0.8 2.6 1 1 0 2 2 2 0 Basic region leucine zipper DUF1664 PF07889.12 KIY44505.1 - 0.25 11.4 2.0 0.5 10.4 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Lzipper-MIP1 PF14389.6 KIY44505.1 - 0.38 11.1 3.6 1.8 8.9 3.6 2.2 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4515 PF14988.6 KIY44505.1 - 0.43 10.4 5.7 0.68 9.7 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) MbeD_MobD PF04899.12 KIY44505.1 - 0.52 10.5 6.3 0.16 12.1 3.1 1.8 2 0 0 2 2 1 0 MbeD/MobD like YabA PF06156.13 KIY44505.1 - 0.55 10.9 3.4 0.97 10.1 1.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA GAS PF13851.6 KIY44505.1 - 0.71 9.2 6.4 1.2 8.5 6.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 KIY44505.1 - 0.71 10.0 3.1 10 6.3 0.2 2.5 1 1 1 2 2 2 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KIY44505.1 - 0.76 10.0 7.7 1.5 9.1 7.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HAUS6_N PF14661.6 KIY44505.1 - 0.91 9.1 4.8 1.5 8.4 4.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.15 KIY44505.1 - 0.93 9.3 3.8 4.5 7.1 3.0 2.2 1 1 0 1 1 1 0 Septum formation initiator CENP-H PF05837.12 KIY44505.1 - 2 8.8 9.3 4.1 7.9 9.3 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KIY44505.1 - 3.6 8.1 11.5 9.1 6.8 11.5 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region U3_assoc_6 PF08640.11 KIY44507.1 - 8e-28 96.3 1.8 2.2e-27 95.0 0.5 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KIY44507.1 - 8.9e-06 26.1 0.1 0.037 14.9 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KIY44507.1 - 0.00043 19.5 0.0 0.00093 18.4 0.0 1.5 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 KIY44507.1 - 0.0066 17.1 0.0 0.66 10.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Asparaginase_II PF06089.12 KIY44508.1 - 0.0016 17.5 0.1 0.0022 17.1 0.1 1.2 1 0 0 1 1 1 1 L-asparaginase II DUF2682 PF10909.8 KIY44508.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) Exotox-A_target PF09102.10 KIY44508.1 - 0.14 12.1 0.6 5.6 6.9 0.1 2.3 1 1 1 2 2 2 0 Exotoxin A, targeting DUF883 PF05957.13 KIY44508.1 - 0.17 12.5 4.4 0.26 11.9 0.2 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) V-ATPase_G_2 PF16999.5 KIY44508.1 - 0.2 12.1 4.8 0.33 11.4 0.6 2.4 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit EccE PF11203.8 KIY44508.1 - 1 9.8 5.4 0.26 11.6 1.0 2.3 2 2 1 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Got1 PF04178.12 KIY44509.1 - 6.4e-17 62.0 17.4 8.8e-17 61.6 17.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family CPP1-like PF11833.8 KIY44509.1 - 0.63 9.7 2.3 0.75 9.4 2.3 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF308 PF03729.13 KIY44509.1 - 1.3 9.4 17.1 0.095 13.0 10.1 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DctQ PF04290.12 KIY44511.1 - 0.95 9.4 6.0 2.2 8.2 0.4 2.4 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Syja_N PF02383.18 KIY44512.1 - 4.6e-76 256.2 0.3 6.8e-76 255.6 0.3 1.2 1 0 0 1 1 1 1 SacI homology domain Cyclin PF08613.11 KIY44513.1 - 2.6e-29 102.6 0.0 7.3e-29 101.2 0.0 1.6 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 KIY44513.1 - 3.4e-06 26.8 0.0 4.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L11_N PF03946.14 KIY44514.1 - 3.8e-24 84.3 0.1 6.8e-24 83.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KIY44514.1 - 4.2e-19 68.8 0.8 7.8e-19 68.0 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.15 KIY44514.1 - 0.06 13.2 0.1 3.7 7.5 0.0 2.7 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region Cpn60_TCP1 PF00118.24 KIY44515.1 - 6.9e-162 539.5 2.0 7.9e-162 539.3 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RIBIOP_C PF04950.12 KIY44516.1 - 6e-118 393.5 0.0 8.5e-118 393.0 0.0 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KIY44516.1 - 9.1e-20 70.5 0.0 2.4e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BAR PF03114.18 KIY44517.1 - 5.8e-48 163.6 2.2 6.8e-48 163.4 2.2 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KIY44517.1 - 0.011 15.4 3.2 0.061 12.9 3.2 1.9 1 1 0 1 1 1 0 Arfaptin-like domain SYF2 PF08231.12 KIY44517.1 - 0.022 15.2 5.5 0.041 14.3 5.5 1.6 1 1 0 1 1 1 0 SYF2 splicing factor LPD39 PF18858.1 KIY44517.1 - 1.1 9.4 10.5 4.6 7.3 3.6 3.3 2 1 2 4 4 4 0 Large polyvalent protein associated domain 39 GNAT_acetyltr_2 PF13718.6 KIY44518.1 - 2.7e-79 265.8 0.0 7.5e-79 264.3 0.0 1.7 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KIY44518.1 - 4.2e-65 219.7 0.0 8.1e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KIY44518.1 - 4.7e-45 153.6 0.0 2.5e-44 151.2 0.0 2.2 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.11 KIY44518.1 - 1.6e-32 111.3 0.0 5e-32 109.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 KIY44518.1 - 0.00097 19.4 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY44518.1 - 0.032 14.7 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PsiB PF06290.11 KIY44518.1 - 0.18 11.3 0.0 0.47 9.9 0.0 1.7 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) Abhydrolase_6 PF12697.7 KIY44519.1 - 8.3e-05 23.3 0.1 9.8e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY44519.1 - 0.0093 15.6 0.1 0.017 14.8 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KIY44519.1 - 0.069 12.0 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Sugar_tr PF00083.24 KIY44520.1 - 1.4e-103 347.2 22.4 1.5e-103 347.1 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY44520.1 - 1.3e-24 86.8 24.0 5.9e-23 81.4 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HECT PF00632.25 KIY44521.1 - 3.4e-99 332.2 0.0 4e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KIY44522.1 - 0.033 14.0 3.0 0.12 12.2 3.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif UvrC_HhH_N PF08459.11 KIY44523.1 - 0.43 10.5 3.4 0.95 9.4 3.0 1.7 1 1 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal bZIP_2 PF07716.15 KIY44526.1 - 2.6e-05 24.2 10.9 2.6e-05 24.2 10.9 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY44526.1 - 0.02 15.0 7.4 0.031 14.4 7.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF3117 PF11314.8 KIY44527.1 - 0.12 12.2 0.8 0.2 11.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) adh_short PF00106.25 KIY44528.1 - 3.1e-37 127.9 0.2 4.2e-37 127.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY44528.1 - 6.9e-30 104.3 0.0 9.8e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY44528.1 - 1.2e-06 28.5 0.3 1.8e-05 24.8 0.3 2.1 1 1 0 1 1 1 1 KR domain PALP PF00291.25 KIY44528.1 - 0.028 13.9 0.4 0.043 13.2 0.4 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Sulfotransfer_3 PF13469.6 KIY44529.1 - 0.0051 17.2 0.0 0.011 16.1 0.0 1.5 2 0 0 2 2 2 1 Sulfotransferase family Thiol_cytolys_C PF17440.2 KIY44530.1 - 0.024 14.8 4.0 0.08 13.1 3.6 2.0 1 1 0 1 1 1 0 Thiol-activated cytolysin beta sandwich domain Arf PF00025.21 KIY44531.1 - 2.1e-36 125.0 0.0 2.4e-34 118.3 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KIY44531.1 - 1.4e-12 47.5 0.1 6.3e-07 28.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KIY44531.1 - 2.5e-11 43.8 0.0 5.2e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIY44531.1 - 1.6e-09 37.5 0.0 3.3e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIY44531.1 - 1.2e-08 34.7 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY44531.1 - 1.3e-05 25.3 0.0 0.00023 21.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIY44531.1 - 5.4e-05 22.7 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KIY44531.1 - 0.00028 21.2 0.0 0.00056 20.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KIY44531.1 - 0.0007 19.2 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 KIY44531.1 - 0.0032 16.7 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KIY44531.1 - 0.0048 16.6 0.1 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KIY44531.1 - 0.0058 17.2 0.2 0.013 16.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KIY44531.1 - 0.0073 16.7 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY44531.1 - 0.013 15.4 0.0 0.46 10.4 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Thymidylate_kin PF02223.17 KIY44531.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_18 PF13238.6 KIY44531.1 - 0.02 15.5 0.0 0.044 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIY44531.1 - 0.021 15.3 0.1 0.036 14.6 0.0 1.4 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 KIY44531.1 - 0.031 13.9 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KIY44531.1 - 0.032 14.1 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KIY44531.1 - 0.032 14.4 0.0 0.072 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KIY44531.1 - 0.048 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KIY44531.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KIY44531.1 - 0.078 12.3 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 KIY44531.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KIY44531.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KIY44531.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KIY44531.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3 PF00933.21 KIY44532.1 - 9.2e-43 146.8 0.0 1.7e-42 146.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KIY44532.1 - 2.4e-42 145.2 0.0 3.8e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIY44532.1 - 1.8e-19 69.6 0.0 3.9e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain SET PF00856.28 KIY44533.1 - 3.5e-12 47.0 0.0 1.4e-11 45.1 0.0 1.9 1 1 0 1 1 1 1 SET domain Cwf_Cwc_15 PF04889.12 KIY44533.1 - 3.2 7.4 6.7 4.8 6.8 6.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein STE3 PF02076.15 KIY44535.1 - 4.1e-86 288.8 26.3 4.5e-86 288.6 26.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor Septin PF00735.18 KIY44536.1 - 1.6e-104 349.1 0.0 2.6e-104 348.5 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIY44536.1 - 4.4e-05 23.5 0.0 0.00013 22.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIY44536.1 - 0.00023 21.3 2.7 0.24 11.5 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 KIY44536.1 - 0.0028 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KIY44536.1 - 0.0053 15.9 0.2 0.011 14.8 0.2 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 KIY44536.1 - 0.0056 16.6 0.3 0.093 12.6 0.4 2.7 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KIY44536.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIY44536.1 - 0.19 11.3 0.2 0.83 9.2 0.0 2.0 2 0 0 2 2 2 0 Ras family AAA_32 PF13654.6 KIY44536.1 - 0.59 8.8 0.0 0.59 8.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain ATP-synt_C PF00137.21 KIY44537.1 - 5e-22 78.0 24.7 8.3e-14 51.7 8.3 2.8 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 KIY44537.1 - 0.0055 17.1 0.1 0.17 12.3 0.0 2.2 2 0 0 2 2 2 1 G0/G1 switch protein 2 Oxidored_q2 PF00420.24 KIY44537.1 - 0.29 10.8 8.0 0.1 12.2 2.8 2.7 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Pkinase_fungal PF17667.1 KIY44538.1 - 6.7e-24 84.4 0.1 7.7e-24 84.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KIY44539.1 - 4.7e-15 55.3 0.0 5.1e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIY44539.1 - 8.2e-08 31.9 0.0 9.5e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44539.1 - 3e-05 23.4 0.0 3.4e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY44540.1 - 1.2e-59 201.9 0.0 1.4e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44540.1 - 5.1e-44 150.5 0.0 6.1e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY44540.1 - 8.3e-07 28.1 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY44540.1 - 0.0028 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY44540.1 - 0.0098 14.9 0.0 0.017 14.1 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain SPATA48 PF15073.6 KIY44540.1 - 0.06 13.6 0.0 0.4 11.0 0.0 2.1 3 0 0 3 3 3 0 Spermatogenesis-associated protein 48 APH PF01636.23 KIY44540.1 - 0.063 13.2 0.0 0.83 9.5 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family F-box-like PF12937.7 KIY44541.1 - 0.0013 18.6 0.1 0.0057 16.5 0.1 2.1 1 1 0 1 1 1 1 F-box-like PatG_C PF18065.1 KIY44541.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 PatG C-terminal DUF3844 PF12955.7 KIY44542.1 - 1.3e-30 105.6 3.4 1.9e-30 105.1 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) PAN_3 PF08277.12 KIY44542.1 - 0.15 11.9 5.0 0.29 11.0 5.0 1.5 1 0 0 1 1 1 0 PAN-like domain EGF_2 PF07974.13 KIY44542.1 - 3.3 8.2 8.7 8.2 6.9 8.7 1.7 1 0 0 1 1 1 0 EGF-like domain Gti1_Pac2 PF09729.9 KIY44543.1 - 6.5e-20 72.0 0.3 2.6e-16 60.2 0.2 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family GRIM-19 PF06212.12 KIY44543.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 GRIM-19 protein Mito_carr PF00153.27 KIY44545.1 - 1.2e-64 214.2 3.8 4.9e-21 74.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CENP-F_leu_zip PF10473.9 KIY44547.1 - 0.0037 17.3 14.2 0.024 14.7 14.2 2.0 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MatP PF06303.12 KIY44547.1 - 0.0076 16.8 3.2 0.051 14.1 0.3 2.7 3 0 0 3 3 2 1 MatP N-terminal domain zf-C3HC4_5 PF17121.5 KIY44547.1 - 0.011 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3584 PF12128.8 KIY44547.1 - 0.012 13.1 9.5 0.013 13.1 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 KIY44547.1 - 0.016 15.5 6.0 0.093 13.0 1.8 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SelA PF03841.13 KIY44547.1 - 0.054 12.5 1.0 0.1 11.6 0.6 1.5 1 1 1 2 2 2 0 L-seryl-tRNA selenium transferase Tmpp129 PF10272.9 KIY44547.1 - 0.055 12.8 0.4 0.83 8.9 0.0 2.1 2 0 0 2 2 2 0 Putative transmembrane protein precursor Myb_DNA-bind_5 PF13873.6 KIY44547.1 - 0.079 13.0 2.3 2.1 8.5 0.3 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Exonuc_VII_L PF02601.15 KIY44547.1 - 0.085 12.4 4.2 0.1 12.1 4.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 KIY44547.1 - 0.17 12.1 15.4 0.33 11.1 4.5 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 VGPC1_C PF16799.5 KIY44547.1 - 0.19 11.7 2.7 2.5 8.2 0.8 2.6 2 1 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 SlyX PF04102.12 KIY44547.1 - 0.21 12.2 7.1 8.7 7.0 1.1 3.4 1 1 2 3 3 3 0 SlyX Prefoldin_2 PF01920.20 KIY44547.1 - 0.23 11.4 13.6 0.23 11.4 1.0 3.3 2 1 1 3 3 3 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 KIY44547.1 - 0.23 11.5 14.0 1.3 9.1 5.0 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Gp-FAR-1 PF05823.12 KIY44547.1 - 0.26 11.6 4.4 2.4 8.5 0.8 2.4 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Nmad5 PF18757.1 KIY44547.1 - 0.28 11.4 4.6 0.58 10.3 4.6 1.5 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 DUF4407 PF14362.6 KIY44547.1 - 0.3 10.4 5.5 0.38 10.1 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KIY44547.1 - 0.32 11.4 2.4 18 5.8 0.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FliD_N PF02465.18 KIY44547.1 - 0.34 11.6 11.6 1.7 9.4 0.4 3.4 2 1 2 4 4 3 0 Flagellar hook-associated protein 2 N-terminus KASH_CCD PF14662.6 KIY44547.1 - 0.34 10.7 11.6 0.23 11.3 4.3 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 KIY44547.1 - 0.42 10.7 13.3 3.6 7.7 12.1 2.3 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding K-box PF01486.17 KIY44547.1 - 0.53 10.5 10.7 2.5 8.3 0.5 2.6 3 0 0 3 3 2 0 K-box region ABC_tran_Xtn PF12848.7 KIY44547.1 - 0.56 10.3 8.5 0.55 10.3 2.3 2.6 2 1 0 2 2 2 0 ABC transporter GAS PF13851.6 KIY44547.1 - 0.58 9.5 14.1 6.7 6.0 14.1 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Bap31_Bap29_C PF18035.1 KIY44547.1 - 0.76 9.8 8.8 0.1 12.6 4.0 2.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1640 PF07798.11 KIY44547.1 - 1.4 9.0 7.8 3.1 7.8 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) V_ATPase_I PF01496.19 KIY44547.1 - 2.3 6.0 5.7 3.6 5.4 5.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 KIY44547.1 - 2.5 7.9 13.1 2.5 8.0 2.2 2.9 1 1 2 3 3 3 0 Septum formation initiator HALZ PF02183.18 KIY44547.1 - 3.6 7.9 11.5 0.82 9.9 2.1 2.8 3 0 0 3 3 2 0 Homeobox associated leucine zipper YabA PF06156.13 KIY44547.1 - 5.5 7.7 9.4 18 6.0 3.2 2.4 1 1 0 2 2 2 0 Initiation control protein YabA JIP_LZII PF16471.5 KIY44547.1 - 7.2 6.9 8.8 25 5.1 0.5 2.9 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 KIY44547.1 - 8.2 6.9 13.3 1.2e+03 0.0 13.3 2.8 1 1 0 1 1 1 0 Cell division protein ZapB Pkinase PF00069.25 KIY44548.1 - 2.3e-07 30.4 0.0 5.3e-06 26.0 0.0 2.3 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44548.1 - 0.0017 17.7 0.0 0.0088 15.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4851 PF16143.5 KIY44548.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) Glyco_hydro_18 PF00704.28 KIY44549.1 - 0.0029 17.4 0.0 0.0032 17.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RINGv PF12906.7 KIY44550.1 - 0.42 10.8 5.6 0.75 10.0 5.6 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KIY44550.1 - 1.9 8.4 5.3 3.8 7.5 5.3 1.5 1 0 0 1 1 1 0 PHD-finger Desulfoferrod_N PF06397.12 KIY44550.1 - 4 7.1 5.4 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain ANAPC8 PF04049.13 KIY44551.1 - 1.1e-17 64.4 0.0 2.8e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KIY44551.1 - 1.2e-13 50.2 9.0 0.00053 19.7 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44551.1 - 1.2e-11 44.4 8.2 6.4e-05 23.5 0.4 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY44551.1 - 5.8e-10 38.6 6.5 0.0015 18.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY44551.1 - 5.2e-07 29.3 16.3 0.005 16.9 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44551.1 - 7.2e-07 28.8 5.2 0.00016 21.3 1.8 2.7 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 KIY44551.1 - 9.5e-07 28.8 4.9 0.45 11.0 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44551.1 - 0.001 19.6 2.3 0.75 10.3 0.5 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY44551.1 - 0.0034 17.5 0.5 0.028 14.5 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44551.1 - 0.0041 17.7 7.6 0.021 15.5 1.3 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY44551.1 - 0.0043 17.0 7.6 0.35 11.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44551.1 - 0.016 15.5 8.3 1.2 9.5 4.4 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Glutaredoxin PF00462.24 KIY44552.1 - 9.4e-12 45.0 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KIY44552.1 - 0.13 12.7 0.0 0.16 12.4 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 KIY44552.1 - 0.15 11.8 0.0 2.9 7.6 0.0 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Con-6 PF10346.9 KIY44553.1 - 3e-34 116.7 7.9 2.9e-13 49.6 0.4 3.3 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.7 KIY44553.1 - 0.017 15.0 0.4 3.9 7.2 0.3 2.1 1 1 1 2 2 2 0 SpoIIIAH-like protein Peptidase_M15_2 PF05951.13 KIY44553.1 - 0.026 14.2 0.1 0.067 12.9 0.1 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF882) SBP_bac_5 PF00496.22 KIY44553.1 - 0.18 10.8 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle ADH_zinc_N PF00107.26 KIY44554.1 - 4.2e-20 72.0 0.0 6.7e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY44554.1 - 0.0014 19.7 0.0 0.0024 18.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY44554.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ELFV_dehydrog PF00208.21 KIY44554.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 KIY44554.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Peptidase_M22 PF00814.25 KIY44555.1 - 3.6e-68 230.2 0.0 4.4e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family HbrB PF08539.11 KIY44556.1 - 4.9e-36 124.3 0.0 5.3e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 HbrB-like BRO1 PF03097.18 KIY44557.1 - 3.9e-24 85.2 0.0 5.1e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain HAD_2 PF13419.6 KIY44558.1 - 1.6e-16 60.9 0.0 3.8e-16 59.7 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY44558.1 - 2e-10 41.4 0.0 2e-09 38.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIY44558.1 - 5.8e-05 23.1 0.0 0.3 11.2 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY44558.1 - 0.00055 20.0 0.0 0.0025 17.8 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.7 KIY44558.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 1 0 1 1 1 0 Acid Phosphatase SEEEED PF14797.6 KIY44559.1 - 0.02 15.0 2.8 0.032 14.4 2.8 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex KDZ PF18758.1 KIY44560.1 - 1.5e-38 132.7 0.4 2.1e-38 132.2 0.4 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIY44561.1 - 1.7e-22 80.2 0.0 2.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY44561.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIY44561.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases APT PF03440.14 KIY44562.1 - 0.052 13.5 0.6 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain Nop53 PF07767.11 KIY44563.1 - 0.0065 15.9 21.9 0.0071 15.8 21.9 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) HSP70 PF00012.20 KIY44563.1 - 1.7 6.8 7.6 1.7 6.7 7.6 1.2 1 0 0 1 1 1 0 Hsp70 protein NYD-SP28_assoc PF14775.6 KIY44565.1 - 0.036 14.2 1.0 0.37 10.9 0.1 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain NYD-SP28 PF14772.6 KIY44565.1 - 0.21 11.7 3.4 0.11 12.5 0.9 1.8 2 0 0 2 2 2 0 Sperm tail HALZ PF02183.18 KIY44565.1 - 1.4 9.2 5.3 0.46 10.8 0.2 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper HMG_box_2 PF09011.10 KIY44566.1 - 0.005 17.4 0.9 0.15 12.7 0.3 3.0 2 0 0 2 2 2 1 HMG-box domain DUF3464 PF11947.8 KIY44566.1 - 0.58 9.9 0.0 0.58 9.9 0.0 2.2 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Dynamitin PF04912.14 KIY44567.1 - 4.7e-63 213.8 0.5 6.5e-63 213.4 0.5 1.2 1 0 0 1 1 1 1 Dynamitin ABC_tran_CTD PF16326.5 KIY44567.1 - 0.042 14.1 5.6 0.51 10.6 0.1 3.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain YPEB PF14620.6 KIY44567.1 - 0.065 12.6 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 YpeB sporulation DprA_WH PF17782.1 KIY44567.1 - 0.42 10.8 11.2 1.1 9.5 0.9 2.9 2 0 0 2 2 2 0 DprA winged helix domain ATG16 PF08614.11 KIY44567.1 - 1.1 9.5 11.8 0.25 11.6 3.4 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KIY44567.1 - 8.2 7.0 9.4 0.43 11.1 0.7 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region Git3 PF11710.8 KIY44568.1 - 3.8e-05 23.6 10.8 8.8e-05 22.4 10.8 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF3149 PF11346.8 KIY44568.1 - 0.12 12.0 3.6 0.096 12.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) SAYSvFN PF10260.9 KIY44568.1 - 0.67 9.9 3.2 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Myb_DNA-binding PF00249.31 KIY44569.1 - 3.5e-13 49.5 0.1 6.5e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KIY44569.1 - 7.2e-11 42.3 0.0 1.8e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KIY44569.1 - 1.1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KIY44569.1 - 0.043 13.6 4.8 0.13 12.1 4.8 1.8 1 1 0 1 1 1 0 Zinc finger, ZZ type CoA_binding_2 PF13380.6 KIY44571.1 - 1.8e-31 109.1 0.0 2e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KIY44571.1 - 0.017 15.8 0.0 0.026 15.2 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain nos_propeller PF18764.1 KIY44571.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat PALP PF00291.25 KIY44572.1 - 2e-48 165.3 0.0 1.5e-47 162.5 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cas_Csy4 PF09618.10 KIY44573.1 - 0.02 15.1 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Ank_5 PF13857.6 KIY44574.1 - 2.3e-05 24.6 0.1 0.002 18.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY44574.1 - 0.00013 22.5 0.0 0.00044 20.8 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY44574.1 - 0.046 14.3 0.4 32 5.6 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat DOCK_N PF16172.5 KIY44576.1 - 3.6e-98 329.0 0.0 1e-97 327.5 0.0 1.8 1 1 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KIY44576.1 - 2.5e-73 247.6 0.2 1.2e-72 245.3 0.0 2.1 2 1 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KIY44576.1 - 1.2e-53 181.8 0.0 3.8e-53 180.2 0.0 2.0 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Methyltransf_16 PF10294.9 KIY44577.1 - 1.9e-16 60.3 0.0 6.8e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KIY44577.1 - 0.0068 17.1 0.1 0.72 10.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KIY44577.1 - 0.0097 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 KIY44577.1 - 0.011 15.5 0.0 0.04 13.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KIY44577.1 - 0.095 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PrmA PF06325.13 KIY44577.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIY44577.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Aldedh PF00171.22 KIY44580.1 - 3.7e-126 421.4 0.0 4.5e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Med27 PF11571.8 KIY44582.1 - 5e-13 49.2 0.5 1.7e-12 47.5 0.1 2.0 2 0 0 2 2 2 1 Mediator complex subunit 27 O-FucT PF10250.9 KIY44583.1 - 1.2e-13 51.5 0.0 2.7e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Porin_OmpG PF09381.10 KIY44583.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) PSP PF04046.16 KIY44583.1 - 0.73 9.8 2.3 4.6 7.2 0.0 2.9 3 0 0 3 3 3 0 PSP GLTP PF08718.11 KIY44584.1 - 1.1e-44 152.3 0.1 1.4e-44 152.0 0.1 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GAF_2 PF13185.6 KIY44585.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.5 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 KIY44585.1 - 0.048 14.3 0.0 0.073 13.7 0.0 1.6 1 1 0 1 1 1 0 GAF domain tRNA-synt_1e PF01406.19 KIY44586.1 - 2.3e-127 424.5 0.0 3.4e-127 424.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KIY44586.1 - 2.4e-08 33.2 1.4 6.9e-05 21.8 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIY44586.1 - 3.4e-06 25.6 0.0 0.0012 17.2 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 KIY44586.1 - 1.1e-05 25.8 0.7 2.7e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.21 KIY44586.1 - 0.068 12.0 2.5 0.25 10.2 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 KIY44586.1 - 0.11 11.3 0.3 3.6 6.4 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (K) Gti1_Pac2 PF09729.9 KIY44587.1 - 3.7e-29 102.1 0.0 2.3e-25 89.7 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Ras PF00071.22 KIY44588.1 - 1e-47 161.7 0.1 1.2e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY44588.1 - 2.7e-16 59.9 0.0 4.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIY44588.1 - 0.00012 21.6 0.0 0.00083 18.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KIY44588.1 - 0.0061 16.1 0.1 0.99 8.9 0.0 2.8 1 1 2 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIY44588.1 - 0.035 14.0 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 KIY44588.1 - 0.042 13.4 0.0 0.066 12.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIY44588.1 - 0.19 11.8 0.1 1.2 9.3 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY44588.1 - 0.19 12.1 0.4 0.67 10.3 0.4 2.0 1 1 0 1 1 1 0 AAA ATPase domain Glyco_trans_4_4 PF13579.6 KIY44590.1 - 0.002 18.6 1.1 0.002 18.6 1.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain RVT_1 PF00078.27 KIY44591.1 - 3.1e-06 26.9 0.0 7.6e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4404 PF14357.6 KIY44591.1 - 0.16 12.7 0.1 0.38 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) zf-RVT PF13966.6 KIY44592.1 - 1.2e-06 29.1 0.3 2.2e-06 28.3 0.3 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Plavaka PF18759.1 KIY44594.1 - 6.5e-112 373.9 0.0 8.6e-112 373.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF659 PF04937.15 KIY44597.1 - 1.3e-07 31.5 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Ribosomal_L30_N PF08079.12 KIY44598.1 - 2.4e-27 95.0 15.9 4.8e-27 94.0 15.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KIY44598.1 - 2.1e-12 46.7 0.4 2.1e-12 46.7 0.4 2.1 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e HMG_box PF00505.19 KIY44599.1 - 0.015 15.7 0.3 0.046 14.2 0.3 1.8 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY44599.1 - 0.056 14.1 0.2 0.11 13.1 0.2 1.4 1 0 0 1 1 1 0 HMG-box domain DUF883 PF05957.13 KIY44599.1 - 0.7 10.5 5.1 16 6.2 0.8 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) API5 PF05918.11 KIY44600.1 - 0.031 13.1 0.1 0.039 12.8 0.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FoP_duplication PF13865.6 KIY44600.1 - 0.47 11.0 12.5 0.96 10.0 12.5 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-CCHC_4 PF14392.6 KIY44603.1 - 0.0011 18.7 0.5 0.0019 17.9 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY44603.1 - 0.052 13.6 3.7 0.12 12.5 3.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 KIY44603.1 - 0.19 11.6 4.2 0.43 10.5 4.2 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4110 PF13422.6 KIY44605.1 - 1.1 9.4 5.3 0.39 10.8 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) PIH1 PF08190.12 KIY44607.1 - 8.3e-26 90.4 0.0 1.7e-25 89.4 0.0 1.4 2 0 0 2 2 2 1 PIH1 N-terminal domain Zn_clus PF00172.18 KIY44611.1 - 0.035 14.2 12.0 0.23 11.6 5.8 2.6 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KIY44611.1 - 0.98 10.0 12.3 1.3 9.6 6.3 2.7 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region zf-RING_2 PF13639.6 KIY44621.1 - 2.5e-08 34.1 9.3 3.8e-08 33.5 9.3 1.3 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KIY44621.1 - 4.7e-05 23.5 7.9 0.0001 22.4 7.9 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KIY44621.1 - 0.00028 20.9 5.7 0.0005 20.1 5.7 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY44621.1 - 0.001 19.3 12.1 0.0036 17.5 12.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KIY44621.1 - 0.0012 18.4 6.9 0.0024 17.4 6.9 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 KIY44621.1 - 0.0015 18.4 2.3 0.0015 18.4 2.3 1.8 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 KIY44621.1 - 0.0022 18.1 8.5 0.0053 16.9 8.4 1.7 1 1 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.25 KIY44621.1 - 0.0077 16.1 7.7 0.015 15.1 7.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KIY44621.1 - 0.011 16.0 8.4 0.036 14.4 8.4 1.8 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.6 KIY44621.1 - 0.016 15.1 10.8 0.038 13.8 10.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 KIY44621.1 - 0.042 13.9 5.5 0.1 12.7 5.5 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 KIY44621.1 - 0.16 11.8 6.4 0.26 11.1 6.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KIY44621.1 - 0.95 9.4 7.7 1.9 8.5 7.7 1.6 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 KIY44621.1 - 3.4 7.6 10.1 53 3.8 10.2 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) p450 PF00067.22 KIY44622.1 - 1.5e-59 202.0 0.1 1.9e-57 195.0 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 Clr5 PF14420.6 KIY44624.1 - 0.022 14.9 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 Clr5 domain Clr5 PF14420.6 KIY44625.1 - 0.0047 17.1 0.1 0.011 15.9 0.1 1.7 1 1 0 1 1 1 1 Clr5 domain Carn_acyltransf PF00755.20 KIY44626.1 - 5.6e-203 675.8 0.0 6.3e-203 675.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ras PF00071.22 KIY44627.1 - 3.8e-56 189.2 0.0 4.4e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY44627.1 - 4.4e-33 114.0 0.0 6.4e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY44627.1 - 9.3e-14 51.3 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY44627.1 - 1e-06 28.3 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY44627.1 - 4.1e-06 26.8 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY44627.1 - 0.00012 21.6 0.0 0.00025 20.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIY44627.1 - 0.00035 21.0 0.0 0.00065 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY44627.1 - 0.004 17.1 0.2 0.014 15.3 0.1 1.8 1 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KIY44627.1 - 0.0051 16.1 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_24 PF13479.6 KIY44627.1 - 0.0087 15.8 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KIY44627.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 KIY44627.1 - 0.021 14.6 0.1 0.053 13.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY44627.1 - 0.027 14.8 0.0 0.062 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KIY44627.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KIY44627.1 - 0.072 12.2 1.5 4.3 6.4 0.3 2.1 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 KIY44627.1 - 0.087 13.3 0.0 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 KIY44627.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KIY44627.1 - 0.12 12.7 0.0 0.54 10.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DAO PF01266.24 KIY44628.1 - 5.9e-24 85.3 0.0 1.2e-23 84.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY44628.1 - 6.1e-08 32.2 0.0 5.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY44628.1 - 8.2e-07 28.6 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY44628.1 - 2.5e-05 24.4 0.0 6.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY44628.1 - 0.0002 20.6 0.1 0.0009 18.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIY44628.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KIY44628.1 - 0.0045 17.4 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Thi4 PF01946.17 KIY44628.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KIY44628.1 - 0.0074 16.8 0.1 0.13 12.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KIY44628.1 - 0.017 14.5 0.2 0.028 13.8 0.2 1.2 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 KIY44628.1 - 0.019 14.0 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KIY44628.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain P2X_receptor PF00864.19 KIY44628.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP P2X receptor HI0933_like PF03486.14 KIY44628.1 - 0.082 11.6 0.1 0.28 9.8 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 KIY44628.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1188 PF06690.11 KIY44628.1 - 0.19 11.3 0.0 0.74 9.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Shikimate_DH PF01488.20 KIY44628.1 - 0.2 11.7 0.0 0.82 9.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_M76 PF09768.9 KIY44629.1 - 9.6e-63 211.0 1.5 1.1e-62 210.8 1.5 1.0 1 0 0 1 1 1 1 Peptidase M76 family NUDIX_2 PF13869.6 KIY44630.1 - 1.2e-83 279.3 0.0 1.4e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4667 PF15700.5 KIY44631.1 - 0.15 12.1 0.4 0.24 11.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SAE2 PF08573.10 KIY44632.1 - 5.6e-25 88.6 5.6 5.6e-25 88.6 5.6 1.8 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Thymidylate_kin PF02223.17 KIY44633.1 - 2.3e-47 161.1 0.0 2.6e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 KIY44633.1 - 0.016 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PRK PF00485.18 KIY44633.1 - 0.036 13.8 0.0 0.079 12.7 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DDE_Tnp_IS1595 PF12762.7 KIY44633.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 2 0 0 2 2 2 0 ISXO2-like transposase domain AAA_18 PF13238.6 KIY44633.1 - 0.14 12.7 0.0 0.34 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Thymidylat_synt PF00303.19 KIY44634.1 - 2.6e-104 348.1 0.0 3e-104 347.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase RrnaAD PF00398.20 KIY44635.1 - 6.6e-60 202.4 0.0 8.7e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KIY44635.1 - 3.9e-07 30.7 0.0 8.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY44635.1 - 3.3e-05 24.5 0.0 6.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY44635.1 - 9.4e-05 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KIY44635.1 - 0.00023 21.0 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KIY44635.1 - 0.00025 21.0 0.1 0.56 10.0 0.1 2.1 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 KIY44635.1 - 0.0006 20.5 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIY44635.1 - 0.00071 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KIY44635.1 - 0.0014 18.2 0.1 0.0039 16.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KIY44635.1 - 0.0064 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 KIY44635.1 - 0.011 14.8 0.0 0.026 13.6 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase Methyltransf_28 PF02636.17 KIY44635.1 - 0.034 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 KIY44635.1 - 0.038 13.8 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KIY44635.1 - 0.056 13.2 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein Cons_hypoth95 PF03602.15 KIY44635.1 - 0.077 12.6 0.1 0.28 10.8 0.0 2.0 2 1 1 3 3 3 0 Conserved hypothetical protein 95 NodS PF05401.11 KIY44635.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KIY44635.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Totivirus_coat PF05518.11 KIY44636.1 - 0.22 9.5 1.8 0.24 9.4 1.8 1.0 1 0 0 1 1 1 0 Totivirus coat protein F-box PF00646.33 KIY44637.1 - 2.6e-07 30.3 0.0 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY44637.1 - 6.3e-07 29.2 0.0 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY44637.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 F-box Peptidase_M48_N PF16491.5 KIY44638.1 - 3.9e-63 212.6 2.9 3.9e-63 212.6 2.9 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KIY44638.1 - 3.3e-33 115.1 0.0 1.5e-31 109.7 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KIY44638.1 - 0.0097 15.1 0.2 0.016 14.4 0.2 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 ECH_1 PF00378.20 KIY44639.1 - 1.5e-53 181.7 0.0 1.9e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY44639.1 - 1.9e-27 96.6 0.1 7.3e-27 94.7 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TPR_2 PF07719.17 KIY44641.1 - 4e-12 45.3 15.2 0.00039 20.3 0.4 8.0 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44641.1 - 1.2e-11 44.4 14.3 0.0026 18.4 0.1 7.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIY44641.1 - 3.6e-08 32.9 13.0 0.0036 17.0 0.1 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY44641.1 - 7.8e-08 32.4 2.2 0.22 11.7 0.0 4.6 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIY44641.1 - 8.6e-08 31.8 5.5 0.00039 20.4 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44641.1 - 5.5e-06 26.8 11.7 0.022 15.2 0.1 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44641.1 - 7.2e-06 26.6 14.7 0.019 15.6 0.5 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44641.1 - 5.7e-05 23.3 14.2 0.87 9.9 0.1 6.4 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIY44641.1 - 0.0082 15.4 3.9 0.33 10.1 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIY44641.1 - 0.012 15.0 8.7 0.046 13.1 0.3 4.7 5 1 0 5 5 5 0 MalT-like TPR region TPR_7 PF13176.6 KIY44641.1 - 0.02 14.9 7.0 0.033 14.2 0.2 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44641.1 - 0.43 10.3 7.6 10 5.9 0.3 4.7 4 1 1 5 5 5 0 TPR repeat TPR_9 PF13371.6 KIY44641.1 - 0.52 10.5 9.5 1.4 9.1 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY44641.1 - 0.66 10.8 0.0 0.66 10.8 0.0 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIY44641.1 - 1.5 9.4 7.9 47 4.7 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY44641.1 - 9.8 7.1 9.5 9.1 7.2 0.5 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Diphthamide_syn PF01866.17 KIY44642.1 - 1.2e-94 317.2 0.1 1.5e-94 316.9 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF1691 PF07950.11 KIY44643.1 - 0.0017 19.0 1.3 0.01 16.6 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1691) TFIIS_M PF07500.14 KIY44646.1 - 9.2e-30 103.4 1.0 9.2e-30 103.4 1.0 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KIY44646.1 - 7.6e-18 64.1 12.0 1.2e-17 63.4 12.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KIY44646.1 - 1.1e-07 31.8 1.5 2.5e-07 30.6 1.0 1.9 1 1 1 2 2 2 1 TFIIS helical bundle-like domain WD40 PF00400.32 KIY44647.1 - 5.4e-43 144.2 15.8 4.4e-08 33.6 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY44647.1 - 8.3e-05 22.8 0.2 0.81 10.0 0.1 4.6 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY44647.1 - 0.0092 15.3 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Nucleoporin_N PF08801.11 KIY44647.1 - 0.061 12.1 0.2 3.1 6.4 0.0 3.1 3 1 1 4 4 4 0 Nup133 N terminal like DUF455 PF04305.14 KIY44648.1 - 1.1e-83 280.7 0.0 1.3e-83 280.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KIY44648.1 - 1.3e-06 28.3 0.1 2.7e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KIY44648.1 - 0.00016 21.6 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain SNARE_assoc PF09335.11 KIY44649.1 - 9.4e-18 64.8 6.7 9.4e-18 64.8 6.7 1.8 2 1 0 2 2 2 1 SNARE associated Golgi protein PhyH PF05721.13 KIY44651.1 - 6.3e-14 52.7 0.0 9.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ank_2 PF12796.7 KIY44652.1 - 1.8e-16 60.5 0.3 3.8e-08 33.8 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY44652.1 - 2.5e-11 43.6 0.5 2.5e-05 24.5 0.2 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIY44652.1 - 3.8e-10 40.1 0.1 0.0041 17.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY44652.1 - 5.1e-10 38.7 0.1 0.0045 17.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KIY44652.1 - 4e-09 36.5 0.0 0.0027 18.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat NtCtMGAM_N PF16863.5 KIY44653.1 - 0.00037 20.7 0.0 0.00044 20.4 0.0 1.1 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Zip PF02535.22 KIY44654.1 - 6.8e-10 38.7 0.2 6.8e-10 38.7 0.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 KIY44655.1 - 6e-27 94.7 13.7 6.7e-27 94.6 13.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4281 PF14108.6 KIY44655.1 - 0.0035 17.7 0.1 0.0059 17.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) Pkinase PF00069.25 KIY44656.1 - 1.8e-65 221.0 0.0 3e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44656.1 - 2.1e-38 132.1 0.0 3.1e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KIY44656.1 - 3.7e-17 61.9 0.0 6.8e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KIY44656.1 - 8.4e-07 28.5 0.1 1.3e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY44656.1 - 1.2e-05 24.8 0.0 2.6e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY44656.1 - 1.9e-05 24.7 0.0 0.00063 19.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY44656.1 - 9.1e-05 21.6 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain WaaY PF06176.11 KIY44656.1 - 0.016 14.8 0.2 0.027 14.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KIY44656.1 - 0.18 11.4 0.2 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KIY44656.1 - 0.22 11.0 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TPR_1 PF00515.28 KIY44657.1 - 6.5e-33 111.2 16.0 3.5e-06 26.6 0.0 10.8 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KIY44657.1 - 6.2e-28 94.6 21.4 0.00048 20.0 0.0 10.7 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44657.1 - 1.8e-19 70.1 16.5 0.0002 22.0 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIY44657.1 - 6.3e-18 64.8 12.4 3.8e-05 23.9 0.0 7.4 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KIY44657.1 - 9.3e-18 62.9 11.0 7.6e-05 22.6 0.0 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY44657.1 - 6.6e-17 60.6 0.8 0.00095 19.4 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44657.1 - 6.5e-14 52.2 14.3 0.00039 20.9 0.6 6.4 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY44657.1 - 1.7e-13 50.1 26.2 0.00049 20.7 0.0 10.0 6 5 5 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY44657.1 - 2.1e-13 49.7 10.2 1.4e-07 31.0 0.0 7.3 5 3 3 8 8 8 3 TPR repeat TPR_9 PF13371.6 KIY44657.1 - 2.6e-10 40.3 8.3 9.5e-05 22.5 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIY44657.1 - 2e-09 36.8 5.7 1.3 9.2 0.1 7.3 6 1 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY44657.1 - 1e-05 25.7 9.7 0.083 13.1 0.1 5.2 3 3 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KIY44657.1 - 0.0031 16.5 0.6 0.0031 16.5 0.6 2.1 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KIY44657.1 - 0.0036 17.8 15.6 1.4 9.8 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIY44657.1 - 0.098 12.6 10.5 24 4.9 0.7 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat zf-CSL PF05207.13 KIY44658.1 - 9.4e-22 76.5 0.5 1.1e-21 76.3 0.5 1.0 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KIY44658.1 - 0.00022 21.3 1.1 0.00034 20.7 1.1 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 KIY44658.1 - 0.0022 16.6 0.5 0.0026 16.4 0.5 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) GAGA PF09237.11 KIY44658.1 - 0.028 14.2 0.2 0.034 13.9 0.2 1.2 1 0 0 1 1 1 0 GAGA factor zinc_ribbon_4 PF13717.6 KIY44658.1 - 0.074 13.0 0.7 0.11 12.4 0.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.6 KIY44658.1 - 0.087 12.6 2.4 0.14 11.9 2.4 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Mito_carr PF00153.27 KIY44659.1 - 3.5e-19 68.5 10.6 4.6e-09 36.1 0.3 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein ThrE PF06738.12 KIY44659.1 - 3 7.2 8.5 0.33 10.3 0.2 3.0 4 0 0 4 4 4 0 Putative threonine/serine exporter SPC12 PF06645.13 KIY44660.1 - 1.2e-23 82.9 0.4 1.3e-23 82.8 0.4 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) APH PF01636.23 KIY44663.1 - 8e-21 75.1 2.0 1.1e-20 74.6 2.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY44663.1 - 0.0002 21.0 0.0 0.00029 20.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KIY44663.1 - 0.064 12.4 0.0 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Fructosamine kinase Dak1 PF02733.17 KIY44664.1 - 2.8e-102 341.8 0.1 5.6e-102 340.8 0.0 1.5 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 KIY44664.1 - 1.4e-40 139.0 2.0 2.3e-40 138.3 2.0 1.4 1 0 0 1 1 1 1 DAK2 domain Fungal_trans PF04082.18 KIY44665.1 - 1.5e-16 60.3 0.0 2.4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY44665.1 - 1.6e-05 25.0 12.6 2.7e-05 24.2 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 KIY44666.1 - 3.6e-15 56.1 0.0 4.7e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY44666.1 - 3.8e-11 43.0 0.0 7.9e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIY44666.1 - 9.3e-08 31.4 0.0 1.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIY44666.1 - 5.2e-07 29.1 0.0 8.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIY44666.1 - 3.5e-06 26.4 0.0 0.0021 17.3 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein KR PF08659.10 KIY44666.1 - 0.056 13.4 0.1 0.71 9.7 0.2 2.4 2 1 0 2 2 2 0 KR domain adh_short_C2 PF13561.6 KIY44666.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY44666.1 - 0.19 11.2 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase LacAB_rpiB PF02502.18 KIY44667.1 - 2e-45 154.2 0.1 2.3e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Lactamase_B_2 PF12706.7 KIY44668.1 - 4.6e-28 98.1 0.0 6.5e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIY44668.1 - 9.3e-06 25.6 0.0 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Bacteriocin_IIc PF10439.9 KIY44669.1 - 0.094 12.8 0.1 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Sensor PF13796.6 KIY44669.1 - 0.095 12.7 15.3 0.15 12.1 15.3 1.3 1 0 0 1 1 1 0 Putative sensor LPG_synthase_TM PF03706.13 KIY44669.1 - 0.16 11.5 18.7 0.75 9.3 18.7 1.8 1 1 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region F_bP_aldolase PF01116.20 KIY44670.1 - 2.5e-74 250.3 0.0 2.8e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MFS_1 PF07690.16 KIY44671.1 - 8.9e-31 107.1 26.8 1.2e-30 106.7 26.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE5 PF17178.4 KIY44671.1 - 0.0041 17.0 8.2 0.0056 16.5 2.2 2.5 2 0 0 2 2 2 2 Membrane-associated sensor RTA1 PF04479.13 KIY44672.1 - 9e-41 139.8 6.3 9e-41 139.8 6.3 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF3995 PF13160.6 KIY44672.1 - 0.044 14.1 1.2 0.044 14.1 1.2 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3995) Skp1 PF01466.19 KIY44675.1 - 3.4e-18 65.5 0.0 2.2e-16 59.7 0.0 2.5 2 1 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIY44675.1 - 3.9e-11 43.0 0.0 6.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF4375 PF14300.6 KIY44675.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) AMP-binding PF00501.28 KIY44676.1 - 1.1e-15 57.2 0.0 1.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 KIY44676.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter TetR_C_3 PF08362.11 KIY44676.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 2 0 0 2 2 2 0 YcdC-like protein, C-terminal region 2OG-FeII_Oxy_2 PF13532.6 KIY44677.1 - 1.3e-15 58.1 0.0 1.7e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_S9 PF00326.21 KIY44679.1 - 1.5e-39 135.6 0.0 3.3e-39 134.5 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIY44679.1 - 2.4e-06 27.0 0.0 0.00027 20.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KIY44679.1 - 9.1e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KIY44679.1 - 3e-05 24.0 0.0 5.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY44679.1 - 0.00054 20.6 0.4 0.00054 20.6 0.4 2.4 2 2 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 KIY44679.1 - 0.0068 15.1 0.0 0.085 11.5 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 KIY44679.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PD40 PF07676.12 KIY44679.1 - 0.049 13.6 0.6 0.69 9.9 0.0 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat OLF PF02191.16 KIY44679.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Olfactomedin-like domain CBFD_NFYB_HMF PF00808.23 KIY44680.1 - 8e-18 64.5 0.4 1.2e-17 63.9 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY44680.1 - 7.1e-06 26.4 0.5 7.1e-06 26.4 0.5 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KIY44680.1 - 0.014 15.5 0.7 0.025 14.7 0.7 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region SLD5_C PF16922.5 KIY44681.1 - 1.8e-10 40.8 0.0 3.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KIY44681.1 - 6.7e-05 23.3 1.0 0.00012 22.5 0.7 1.6 1 1 0 1 1 1 1 GINS complex protein TAFII28 PF04719.14 KIY44682.1 - 5.5e-34 116.1 0.1 7.4e-34 115.7 0.1 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KIY44682.1 - 0.0073 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hydantoinase_A PF01968.18 KIY44682.1 - 0.061 12.6 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase PRMT5 PF05185.16 KIY44682.1 - 0.093 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase F-box-like PF12937.7 KIY44684.1 - 0.0011 18.8 3.0 0.0018 18.1 0.0 2.8 3 0 0 3 3 3 1 F-box-like tRNA-synt_1b PF00579.25 KIY44685.1 - 8.9e-54 182.8 0.0 1.8e-53 181.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TFIIIC_sub6 PF10419.9 KIY44686.1 - 9.8e-18 63.8 0.0 1.5e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain FtsJ PF01728.19 KIY44687.1 - 1.3e-47 162.2 0.0 1.5e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Gpi1 PF05024.15 KIY44688.1 - 2.4e-63 213.6 10.0 3.7e-63 213.0 10.0 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.22 KIY44689.1 - 9.7e-54 181.3 0.0 1.1e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY44689.1 - 1.8e-22 79.8 0.0 2.6e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY44689.1 - 2.8e-08 33.4 0.0 7e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIY44689.1 - 0.0001 22.3 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KIY44689.1 - 0.0092 15.4 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY44689.1 - 0.021 14.4 0.0 0.069 12.7 0.0 1.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KIY44689.1 - 0.16 11.4 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-H2C2_2 PF13465.6 KIY44690.1 - 1.3e-07 31.7 3.3 1.6e-05 25.1 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIY44690.1 - 6.6e-07 29.4 14.0 1.4e-05 25.3 0.4 4.7 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY44690.1 - 3.1e-05 24.4 4.9 0.019 15.7 0.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIY44690.1 - 0.00017 22.2 4.3 0.15 12.8 1.8 3.0 2 1 1 3 3 3 2 FOXP coiled-coil domain Zap1_zf2 PF18217.1 KIY44690.1 - 0.7 9.9 0.0 0.7 9.9 0.0 2.7 3 1 0 3 3 3 0 Zap1 zinc finger 2 Pkinase PF00069.25 KIY44691.1 - 1e-19 70.9 0.0 1.2e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44691.1 - 2.8e-09 36.6 0.0 4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY44691.1 - 1.1e-07 31.0 0.4 1.4e-07 30.7 0.4 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY44691.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glycogen_syn PF05693.13 KIY44692.1 - 0 1097.3 0.0 0 1097.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KIY44692.1 - 7.6e-08 32.1 0.0 0.00041 19.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIY44692.1 - 4.7e-07 30.3 0.0 0.0015 19.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KIY44692.1 - 1.5e-06 28.1 0.1 4.5e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 KIY44692.1 - 1.5e-05 25.1 0.8 2.7e-05 24.2 0.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIY44692.1 - 2.2e-05 25.0 0.1 5.2e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Septin PF00735.18 KIY44694.1 - 1.2e-112 375.8 0.2 1.8e-112 375.2 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIY44694.1 - 2.7e-08 33.9 0.1 7.2e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY44694.1 - 1.3e-07 31.6 0.9 2e-06 27.8 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KIY44694.1 - 2.1e-05 24.1 3.1 0.00072 19.2 0.1 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KIY44694.1 - 6.9e-05 23.1 0.1 0.00016 21.9 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIY44694.1 - 0.00016 22.1 0.1 0.00056 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY44694.1 - 0.00036 20.8 0.7 0.002 18.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 KIY44694.1 - 0.0016 17.8 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_15 PF13175.6 KIY44694.1 - 0.0019 18.0 0.0 0.0062 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 KIY44694.1 - 0.002 17.9 1.0 0.15 11.8 0.1 2.6 2 1 1 3 3 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KIY44694.1 - 0.005 17.4 0.1 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 KIY44694.1 - 0.01 15.6 0.2 0.023 14.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 KIY44694.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.7 1 0 0 1 1 1 0 Ras family NB-ARC PF00931.22 KIY44694.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KIY44694.1 - 0.016 14.8 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KIY44694.1 - 0.041 13.9 6.7 0.68 10.0 0.2 3.0 2 1 1 3 3 3 0 Dynamin family SRPRB PF09439.10 KIY44694.1 - 0.05 13.0 0.4 0.11 12.0 0.1 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 KIY44694.1 - 0.056 13.0 0.2 0.16 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KIY44694.1 - 0.061 12.9 0.1 0.15 11.6 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 KIY44694.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Bac_DnaA PF00308.18 KIY44694.1 - 0.1 12.4 2.7 2.4 7.9 0.3 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KIY44694.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 KIY44694.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KIY44694.1 - 0.31 10.6 1.1 0.71 9.4 0.1 2.2 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1129 PF06570.11 KIY44695.1 - 0.14 11.7 2.2 0.22 11.0 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Phage_holin_3_1 PF05106.12 KIY44695.1 - 4.9 7.7 7.8 1.3 9.5 0.5 2.3 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) PDEase_I_N PF08499.12 KIY44696.1 - 0.029 14.2 3.9 0.038 13.8 0.2 3.0 4 0 0 4 4 4 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF1129 PF06570.11 KIY44698.1 - 0.14 11.7 2.2 0.23 10.9 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) T_cell_tran_alt PF15128.6 KIY44698.1 - 0.39 10.5 3.4 20 5.1 0.0 2.9 3 0 0 3 3 3 0 T-cell leukemia translocation-altered Phage_holin_3_1 PF05106.12 KIY44698.1 - 5.1 7.6 7.8 1.3 9.5 0.5 2.3 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) PDEase_I_N PF08499.12 KIY44699.1 - 0.021 14.7 3.5 0.034 14.0 0.2 3.0 4 0 0 4 4 4 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Mid1 PF12929.7 KIY44700.1 - 2.6e-54 185.1 0.0 3.6e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KIY44700.1 - 0.00038 21.0 2.0 0.048 14.3 0.2 2.7 2 0 0 2 2 2 2 Fz domain ABC1 PF03109.16 KIY44701.1 - 1.3e-23 83.4 0.0 3.2e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 KIY44701.1 - 0.0081 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family tRNA-synt_1 PF00133.22 KIY44702.1 - 1.2e-213 710.8 0.0 2e-212 706.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIY44702.1 - 2.9e-32 111.7 0.2 6.3e-32 110.6 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIY44702.1 - 2.8e-14 52.7 0.1 3.8e-07 29.2 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KIY44702.1 - 1.7e-10 40.7 0.2 2.6e-07 30.3 0.1 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KIY44702.1 - 0.00067 19.9 1.6 0.00067 19.9 1.6 2.7 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 KIY44702.1 - 0.0097 15.3 0.0 0.3 10.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain STAC2_u1 PF16664.5 KIY44702.1 - 7.4 7.0 6.5 54 4.2 5.1 2.3 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF1524 PF07510.11 KIY44703.1 - 6.6e-09 35.8 0.0 7.5e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KIY44703.1 - 0.16 11.9 0.8 0.34 10.9 0.8 1.8 1 1 0 1 1 1 0 HNH endonuclease Peptidase_C12 PF01088.21 KIY44704.1 - 8.5e-56 189.0 0.0 1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UAA PF08449.11 KIY44705.1 - 4.4e-71 239.6 11.1 6e-71 239.1 11.1 1.2 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KIY44705.1 - 3.3e-06 26.6 11.5 0.00013 21.3 2.7 2.1 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport CRT-like PF08627.10 KIY44705.1 - 0.00073 18.6 1.7 0.00073 18.6 1.7 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Tetraspanin PF00335.20 KIY44705.1 - 0.053 13.2 0.7 0.053 13.2 0.7 2.2 2 1 0 2 2 2 0 Tetraspanin family Per1 PF04080.13 KIY44705.1 - 0.12 12.1 1.8 0.24 11.1 1.8 1.5 1 0 0 1 1 1 0 Per1-like family Peptidase_C14 PF00656.22 KIY44706.1 - 2.4e-59 201.3 0.0 3.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF4451 PF14616.6 KIY44707.1 - 1.5e-13 51.0 1.4 2e-13 50.6 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) zf-A20 PF01754.16 KIY44707.1 - 7.9 6.5 6.5 0.84 9.6 2.1 1.7 2 0 0 2 2 2 0 A20-like zinc finger Zn_clus PF00172.18 KIY44708.1 - 1.8e-06 28.0 8.5 3e-06 27.3 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY44708.1 - 0.00081 18.5 0.9 0.0067 15.5 0.1 2.1 1 1 0 2 2 2 1 Fungal specific transcription factor domain BAR_2 PF10455.9 KIY44709.1 - 1.2e-48 165.8 1.8 2.3e-48 164.8 1.8 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KIY44709.1 - 5.7e-17 62.2 2.4 7.5e-16 58.5 2.4 2.0 1 1 0 1 1 1 1 BAR domain CHAD PF05235.14 KIY44709.1 - 0.0004 20.4 4.0 0.0065 16.5 4.0 2.1 1 1 0 1 1 1 1 CHAD domain DUF3575 PF12099.8 KIY44709.1 - 0.063 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) RPN6_N PF18055.1 KIY44709.1 - 0.07 13.5 4.9 0.11 12.9 0.5 2.8 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4642 PF15484.6 KIY44709.1 - 0.081 13.2 0.6 0.15 12.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) EMP24_GP25L PF01105.24 KIY44710.1 - 5.5e-43 147.0 0.0 6.3e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 KIY44710.1 - 0.097 13.1 0.2 0.097 13.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Lipase_GDSL_2 PF13472.6 KIY44711.1 - 1.8e-06 28.5 0.1 2.4e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY44711.1 - 0.00036 20.5 0.0 0.0013 18.8 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MutS_V PF00488.21 KIY44711.1 - 0.0046 17.0 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 MutS domain V Hydrophobin PF01185.18 KIY44712.1 - 1.1e-21 77.3 9.6 1.1e-21 77.3 9.6 3.3 2 1 1 3 3 3 1 Fungal hydrophobin Lipase_3 PF01764.25 KIY44713.1 - 2e-28 99.1 0.0 2.7e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KIY44713.1 - 0.12 11.9 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cyt-b5 PF00173.28 KIY44714.1 - 4.4e-12 46.0 0.0 5.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S10 PF00338.22 KIY44715.1 - 4.6e-27 94.1 0.0 5.7e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Hydrophobin PF01185.18 KIY44716.1 - 1.4e-20 73.7 6.9 2e-20 73.2 6.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin TPPII_N PF12583.8 KIY44716.1 - 0.67 10.5 5.4 0.95 10.0 5.4 1.1 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Tubulin PF00091.25 KIY44717.1 - 2e-68 230.5 0.0 4.8e-68 229.2 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY44717.1 - 1.1e-41 141.9 0.1 1.8e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIY44717.1 - 6.3e-06 26.5 0.3 1.8e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KIY44717.1 - 0.0033 16.7 0.0 0.052 12.7 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KIY44717.1 - 0.02 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Hydrophobin PF01185.18 KIY44718.1 - 1.3e-14 54.5 4.3 1.3e-14 54.5 4.3 1.9 1 1 1 2 2 2 2 Fungal hydrophobin CPSase_L_D2 PF02786.17 KIY44719.1 - 2.2e-111 370.4 0.7 2.7e-80 268.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KIY44719.1 - 6.5e-49 165.0 0.0 1.8e-48 163.6 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KIY44719.1 - 1.1e-46 159.0 0.0 1.1e-44 152.5 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KIY44719.1 - 1.6e-45 154.8 0.0 3.4e-45 153.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KIY44719.1 - 3.6e-40 137.1 0.3 1.3e-39 135.3 0.1 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KIY44719.1 - 3.1e-32 111.8 0.0 6.8e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 KIY44719.1 - 2.2e-19 69.8 0.3 3.4e-10 39.8 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIY44719.1 - 2.3e-18 66.3 0.2 8.6e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 KIY44719.1 - 7.4e-17 61.3 0.0 2.7e-16 59.5 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 KIY44719.1 - 7.5e-06 25.7 0.1 0.0011 18.7 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KIY44719.1 - 5.6e-05 23.0 0.1 0.015 15.1 0.0 2.9 3 0 0 3 3 3 1 Peptidase C26 RimK PF08443.11 KIY44719.1 - 9.9e-05 22.0 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KIY44719.1 - 0.0025 17.3 0.1 1.3 8.5 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KIY44719.1 - 0.0068 16.2 0.0 1.4 8.7 0.0 4.2 6 0 0 6 6 6 1 DJ-1/PfpI family GARS_A PF01071.19 KIY44719.1 - 0.0077 16.0 0.1 0.41 10.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KIY44719.1 - 0.041 13.9 0.2 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 ATP-grasp domain zf-H2C2_2 PF13465.6 KIY44720.1 - 5.5e-09 36.1 6.0 6.2e-07 29.6 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIY44720.1 - 2e-08 34.2 14.8 6.8e-06 26.3 0.3 3.9 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY44720.1 - 1.9e-07 31.3 8.0 0.0059 17.3 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIY44720.1 - 1e-06 29.3 6.5 0.013 16.1 1.9 3.1 2 1 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KIY44720.1 - 3.6e-06 26.8 7.1 0.0019 18.2 0.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KIY44720.1 - 0.0037 17.6 1.2 7.1 7.2 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf_ZIC PF18366.1 KIY44720.1 - 0.18 11.9 2.7 1.4 9.1 0.4 3.2 4 1 0 4 4 4 0 Zic proteins zinc finger domain zf-H2C2_5 PF13909.6 KIY44720.1 - 0.27 11.0 2.4 2.1 8.2 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 KIY44720.1 - 0.39 10.9 0.8 25 5.0 0.1 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger OrsD PF12013.8 KIY44720.1 - 0.43 11.0 2.7 23 5.5 0.6 2.8 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf_C2H2_ZHX PF18387.1 KIY44720.1 - 1.1 9.0 2.8 15 5.3 0.1 2.7 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Zap1_zf2 PF18217.1 KIY44720.1 - 5.2 7.2 10.3 1.3 9.1 4.5 2.6 2 0 0 2 2 2 0 Zap1 zinc finger 2 Hydrophobin PF01185.18 KIY44721.1 - 7e-15 55.4 1.7 7e-15 55.4 1.7 1.7 2 0 0 2 2 2 1 Fungal hydrophobin Mucin PF01456.17 KIY44721.1 - 0.013 15.4 21.7 0.019 15.0 21.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2771 PF10969.8 KIY44721.1 - 0.3 11.1 2.1 0.45 10.5 1.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2771) Med13_C PF06333.12 KIY44721.1 - 0.33 10.2 5.7 0.4 9.9 5.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SSP160 PF06933.11 KIY44721.1 - 0.63 8.2 21.0 0.96 7.6 21.0 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Hydrophobin PF01185.18 KIY44722.1 - 1e-20 74.1 5.7 1e-20 74.1 5.7 1.9 2 0 0 2 2 2 1 Fungal hydrophobin Mucin PF01456.17 KIY44722.1 - 0.089 12.8 28.5 0.13 12.2 28.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein EnY2 PF10163.9 KIY44723.1 - 2.3e-13 50.3 0.0 3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 MF_alpha_N PF05436.11 KIY44724.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DNA_pol_E_B PF04042.16 KIY44725.1 - 1.7e-21 76.6 0.0 2.1e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pet100 PF09803.9 KIY44727.1 - 3.6e-24 85.0 0.0 4.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Pet100 PLA2_B PF01735.18 KIY44728.1 - 3.2e-92 309.5 2.5 6.4e-92 308.5 2.5 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain CK_II_beta PF01214.18 KIY44729.1 - 2e-79 265.6 0.0 2.4e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DnaJ-X PF14308.6 KIY44730.1 - 3.1e-53 180.4 0.2 5.6e-53 179.5 0.2 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 KIY44730.1 - 1.1e-25 89.6 0.6 1.1e-25 89.6 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain Mu-like_Pro PF10123.9 KIY44730.1 - 0.0047 16.5 2.7 0.77 9.3 0.1 2.3 2 1 0 2 2 2 2 Mu-like prophage I protein Peptidase_S41_N PF11918.8 KIY44730.1 - 0.031 14.5 0.2 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP PEX11 PF05648.14 KIY44730.1 - 0.13 11.7 1.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4355 PF14265.6 KIY44730.1 - 0.24 11.7 8.5 1.9 8.8 1.9 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Wbp11 PF09429.10 KIY44730.1 - 0.53 10.7 9.8 3.7 8.0 0.8 2.8 3 0 0 3 3 3 0 WW domain binding protein 11 Rft-1 PF04506.13 KIY44731.1 - 1.3e-121 406.9 10.5 1.5e-121 406.7 10.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 KIY44731.1 - 1.7e-05 24.2 3.1 4.9e-05 22.7 3.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein zf-C2H2_aberr PF17017.5 KIY44733.1 - 0.0048 17.1 5.7 0.54 10.4 0.2 2.6 3 0 0 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KIY44733.1 - 0.039 14.4 1.3 0.039 14.4 1.3 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY44733.1 - 1.5 9.9 15.4 1.2 10.1 0.7 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Xan_ur_permease PF00860.20 KIY44735.1 - 4.2e-17 61.9 26.9 3e-09 36.1 7.5 3.6 3 1 0 3 3 3 2 Permease family MFS_MOT1 PF16983.5 KIY44735.1 - 0.53 10.7 12.1 0.034 14.5 4.0 2.6 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily FA_hydroxylase PF04116.13 KIY44736.1 - 3.3e-20 72.8 17.5 3.3e-20 72.8 17.5 2.2 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Med26 PF08711.11 KIY44737.1 - 6.2e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Peripla_BP_3 PF13377.6 KIY44737.1 - 0.034 14.5 0.2 0.069 13.5 0.2 1.5 1 0 0 1 1 1 0 Periplasmic binding protein-like domain DUF2868 PF11067.8 KIY44737.1 - 1.3 8.5 5.0 5.7 6.3 6.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) zf-H2C2_2 PF13465.6 KIY44738.1 - 1.1e-05 25.6 18.6 0.00014 22.1 2.0 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY44738.1 - 0.013 16.3 14.7 0.43 11.6 0.8 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY44738.1 - 0.013 15.9 0.8 0.013 15.9 0.8 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type PP2C PF00481.21 KIY44739.1 - 0.001 18.8 0.0 0.65 9.6 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KIY44739.1 - 0.0075 16.2 0.0 0.058 13.3 0.0 2.2 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KIY44739.1 - 0.071 12.7 3.2 1.5 8.5 0.1 2.6 2 1 0 2 2 2 0 Protein phosphatase 2C BUD22 PF09073.10 KIY44739.1 - 0.46 9.8 5.4 0.78 9.0 5.4 1.2 1 0 0 1 1 1 0 BUD22 PAT1 PF09770.9 KIY44740.1 - 9.3e-83 279.0 0.0 1.3e-82 278.5 0.0 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 ZapB PF06005.12 KIY44740.1 - 0.028 14.9 0.0 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Cell division protein ZapB zf-H2C2_2 PF13465.6 KIY44741.1 - 0.00013 22.2 0.1 0.00013 22.2 0.1 3.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY44741.1 - 0.16 12.9 7.1 0.31 12.0 0.2 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIY44741.1 - 0.18 11.6 11.6 1.1 9.1 0.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY44741.1 - 0.81 10.3 0.2 0.81 10.3 0.2 3.3 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-met2 PF12907.7 KIY44741.1 - 1.1 9.5 3.1 23 5.2 0.3 2.3 1 1 1 2 2 2 0 Zinc-binding GRP PF07172.11 KIY44742.1 - 0.64 10.8 8.3 1.1 10.0 8.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family DRMBL PF07522.14 KIY44747.1 - 1.9e-05 24.8 0.6 6.1e-05 23.2 0.0 2.2 3 0 0 3 3 3 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KIY44747.1 - 0.012 15.2 1.1 0.025 14.1 1.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain C2 PF00168.30 KIY44748.1 - 2e-08 34.5 0.1 2.4e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 C2 domain Mit_KHE1 PF10173.9 KIY44749.1 - 2.5e-49 167.9 0.0 3.5e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related BCD PF15461.6 KIY44749.1 - 0.016 14.7 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Es2 PF09751.9 KIY44750.1 - 0.0014 18.5 0.6 0.0018 18.1 0.6 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 DUF4110 PF13422.6 KIY44752.1 - 0.004 17.2 0.3 0.004 17.2 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Motile_Sperm PF00635.26 KIY44753.1 - 5.2e-28 97.1 0.0 8.9e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KIY44753.1 - 0.005 17.0 0.1 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 KIY44753.1 - 0.042 14.1 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Motile_Sperm PF00635.26 KIY44754.1 - 5.6e-11 42.3 0.1 1.7e-10 40.7 0.1 1.8 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Pkinase PF00069.25 KIY44755.1 - 2.7e-65 220.4 0.0 3.2e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44755.1 - 4.4e-35 121.2 0.0 5.8e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY44755.1 - 0.043 12.8 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Glycos_transf_2 PF00535.26 KIY44756.1 - 3.4e-24 85.5 0.0 4.2e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIY44756.1 - 2.1e-12 47.4 0.0 5.4e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIY44756.1 - 0.00088 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KIY44756.1 - 0.06 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Band_7 PF01145.25 KIY44757.1 - 5.9e-22 78.5 0.2 9e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family LIP1 PF15904.5 KIY44757.1 - 0.074 13.4 0.4 0.18 12.1 0.4 1.7 1 1 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 Pkinase PF00069.25 KIY44759.1 - 1.1e-69 234.8 0.0 1.3e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44759.1 - 6e-33 114.2 0.0 8.3e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIY44759.1 - 2.3e-10 41.0 0.9 5.5e-10 39.8 0.6 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KIY44759.1 - 2.7e-07 29.9 0.2 4.1e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY44759.1 - 1.1e-06 28.2 0.0 3.3e-06 26.6 0.0 1.7 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KIY44759.1 - 0.001 18.8 0.1 0.18 11.4 0.0 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY44759.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY44759.1 - 0.05 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GH131_N PF18271.1 KIY44761.1 - 3.1e-51 174.5 4.4 4.6e-51 174.0 4.4 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain RSN1_7TM PF02714.15 KIY44762.1 - 4.5e-41 141.0 16.3 1.2e-40 139.5 16.3 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KIY44762.1 - 6.4e-20 72.1 0.0 1.3e-14 54.8 0.0 3.0 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIY44762.1 - 2.5e-18 66.3 2.8 2.5e-18 66.3 2.8 2.7 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 KIY44762.1 - 0.091 12.9 0.4 0.66 10.2 0.3 2.5 3 0 0 3 3 3 0 Extracellular tail, of 10TM putative phosphate transporter ETC_C1_NDUFA4 PF04800.12 KIY44763.1 - 4.1e-35 119.9 0.0 5.7e-35 119.5 0.0 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region PROCN PF08083.11 KIY44764.1 - 8.9e-229 759.1 8.5 1.4e-228 758.5 7.7 1.7 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KIY44764.1 - 8e-127 421.5 0.6 2e-126 420.3 0.6 1.7 2 0 0 2 2 2 1 PRP8 domain IV core PRO8NT PF08082.11 KIY44764.1 - 4.2e-84 280.0 2.6 4.2e-84 280.0 2.6 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 KIY44764.1 - 2.6e-83 277.7 6.3 7.4e-83 276.2 3.1 2.7 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 KIY44764.1 - 9.1e-73 242.7 0.1 1.7e-72 241.8 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KIY44764.1 - 2.2e-47 159.3 0.4 5.3e-47 158.1 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KIY44764.1 - 1.3e-40 138.2 0.0 2.7e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KIY44764.1 - 0.00039 20.4 0.0 0.00085 19.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Corona_5a PF06336.11 KIY44764.1 - 0.037 14.0 0.3 0.14 12.1 0.3 2.1 1 0 0 1 1 1 0 Coronavirus 5a protein adh_short_C2 PF13561.6 KIY44765.1 - 6.4e-40 137.2 0.1 1.6e-38 132.6 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY44765.1 - 8.1e-34 116.8 0.0 1.8e-33 115.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY44765.1 - 2.4e-07 30.8 0.2 5.4e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 KR domain MelC1 PF06236.11 KIY44765.1 - 0.04 14.0 0.2 0.8 9.8 0.0 2.8 3 0 0 3 3 3 0 Tyrosinase co-factor MelC1 DpaA_N PF16924.5 KIY44765.1 - 0.11 12.6 0.0 6.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain 3HCDH_N PF02737.18 KIY44765.1 - 0.17 11.8 0.7 0.7 9.8 0.4 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Alpha_GJ PF03229.13 KIY44766.1 - 0.0061 17.1 10.5 0.0061 17.1 10.5 2.4 2 0 0 2 2 2 1 Alphavirus glycoprotein J DUF1180 PF06679.12 KIY44766.1 - 0.0076 16.7 4.8 0.0076 16.7 4.8 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1180) Stevor PF17410.2 KIY44766.1 - 0.018 14.6 1.0 0.033 13.7 1.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 KIY44766.1 - 0.019 14.9 0.0 0.052 13.5 0.0 1.7 1 1 0 1 1 1 0 TMEM154 protein family FSA_C PF10479.9 KIY44766.1 - 1.2 7.2 10.8 2 6.5 10.8 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mito_carr PF00153.27 KIY44767.1 - 1.7e-74 245.8 0.1 8.2e-27 93.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF21 PF01595.20 KIY44768.1 - 1e-32 113.3 1.8 1e-32 113.3 1.8 1.7 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIY44768.1 - 0.025 15.0 0.9 12 6.4 0.0 3.9 3 1 0 3 3 3 0 CBS domain RRM_1 PF00076.22 KIY44769.1 - 2.8e-50 168.0 1.0 2.9e-17 62.3 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY44769.1 - 8.2e-14 51.2 0.0 2.7e-05 23.9 0.0 4.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KIY44769.1 - 3e-05 24.0 0.0 4.1 7.6 0.0 4.1 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KIY44769.1 - 0.00016 21.6 0.0 3.3 7.8 0.0 3.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Suf PF05843.14 KIY44769.1 - 0.006 16.6 6.2 0.033 14.2 6.2 2.1 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) RRM_3 PF08777.11 KIY44769.1 - 0.037 14.1 0.1 28 4.8 0.0 4.2 4 0 0 4 4 4 0 RNA binding motif DUF3887 PF13026.6 KIY44769.1 - 0.087 13.7 0.0 27 5.6 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) Pkinase PF00069.25 KIY44770.1 - 1e-15 57.8 0.0 1.3e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain NUDIX PF00293.28 KIY44771.1 - 1.6e-16 60.6 0.0 2.8e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KIY44771.1 - 1.3e-10 41.9 0.1 2.6e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KIY44771.1 - 2.9e-05 23.6 0.2 5.8e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KIY44771.1 - 0.13 12.0 0.6 0.23 11.3 0.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain FMN_dh PF01070.18 KIY44772.1 - 3.5e-122 407.8 0.1 4.2e-122 407.5 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIY44772.1 - 1.4e-14 54.0 0.0 2.9e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KIY44772.1 - 4.8e-05 22.7 0.0 7.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIY44772.1 - 0.00011 21.3 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KIY44772.1 - 0.032 13.5 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Macro PF01661.21 KIY44773.1 - 2.4e-20 72.8 0.0 3e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Macro domain HpcH_HpaI PF03328.14 KIY44774.1 - 1.6e-32 112.5 0.0 2.5e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KIY44774.1 - 7.9e-10 38.4 0.1 3.8e-07 29.6 0.1 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PLDc_2 PF13091.6 KIY44775.1 - 7.3e-17 61.5 0.0 9.5e-09 35.2 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KIY44775.1 - 5.6e-16 58.5 5.1 3.5e-13 49.5 0.5 3.8 3 0 0 3 3 3 2 PX domain PLDc PF00614.22 KIY44775.1 - 2.7e-13 49.5 1.0 6.1e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif HSCB_C PF07743.13 KIY44776.1 - 9.3e-09 35.7 1.8 9.3e-09 35.7 1.8 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KIY44776.1 - 7e-05 22.9 0.3 0.00021 21.3 0.0 1.9 2 1 0 2 2 2 1 DnaJ domain UPF0547 PF10571.9 KIY44776.1 - 0.19 11.9 2.4 0.39 10.9 2.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 ThiF PF00899.21 KIY44777.1 - 6.6e-30 104.3 0.0 8.6e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family Fungal_trans PF04082.18 KIY44778.1 - 8.9e-21 74.1 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY44778.1 - 1.4e-06 28.3 11.8 2.4e-06 27.6 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.6 KIY44779.1 - 0.00013 22.0 0.0 0.0092 16.2 0.0 2.7 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 KIY44779.1 - 0.00021 21.3 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 Pentatricopeptide repeat domain E3_UbLigase_R4 PF13764.6 KIY44779.1 - 0.059 11.5 0.4 0.47 8.6 0.0 2.2 3 0 0 3 3 3 0 E3 ubiquitin-protein ligase UBR4 TPR_14 PF13428.6 KIY44779.1 - 0.096 13.6 0.0 16 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GRASP55_65 PF04495.14 KIY44780.1 - 9.1e-58 194.5 0.0 3e-43 147.4 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KIY44780.1 - 7.6e-06 26.2 0.0 0.019 15.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KIY44780.1 - 2.8e-05 23.9 0.1 0.00067 19.5 0.0 2.7 3 0 0 3 3 3 1 PDZ domain F-box-like PF12937.7 KIY44781.1 - 3.3e-07 30.1 0.1 3.3e-07 30.1 0.1 2.6 3 0 0 3 3 3 1 F-box-like AMP-binding PF00501.28 KIY44782.1 - 1.9e-76 257.3 0.0 2.7e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY44782.1 - 7.8e-16 58.8 0.2 3.1e-15 56.9 0.2 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PRiA4_ORF3 PF07929.11 KIY44783.1 - 3.2e-16 59.5 0.1 2e-15 57.0 0.1 2.0 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein ABC_membrane PF00664.23 KIY44784.1 - 2.9e-99 332.2 29.5 1.7e-51 175.5 13.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY44784.1 - 8.4e-70 233.6 0.1 3.6e-34 118.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY44784.1 - 9.2e-14 51.4 3.1 0.00013 21.5 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY44784.1 - 1.1e-07 32.4 1.5 0.0028 18.1 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KIY44784.1 - 3.1e-07 29.6 1.8 0.0039 16.1 0.0 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 KIY44784.1 - 1.4e-06 28.4 0.5 0.24 11.2 0.1 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KIY44784.1 - 4.5e-06 27.0 2.3 0.21 11.9 0.1 3.9 3 2 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KIY44784.1 - 5.1e-06 26.1 0.1 0.024 14.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KIY44784.1 - 8.2e-06 25.8 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KIY44784.1 - 1.2e-05 24.7 0.0 0.026 13.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 KIY44784.1 - 6.2e-05 23.0 0.0 0.37 10.7 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_30 PF13604.6 KIY44784.1 - 7.8e-05 22.5 1.1 0.49 10.1 0.0 3.8 4 1 0 4 4 4 2 AAA domain G-alpha PF00503.20 KIY44784.1 - 0.00017 20.9 0.0 0.47 9.6 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 KIY44784.1 - 0.0005 20.3 2.6 1 9.6 0.5 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KIY44784.1 - 0.0012 19.2 2.5 2.2 8.7 0.2 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIY44784.1 - 0.0013 18.6 0.0 0.63 9.9 0.0 3.3 3 0 0 3 3 3 1 Adenylylsulphate kinase AAA_5 PF07728.14 KIY44784.1 - 0.0014 18.7 0.7 5.1 7.1 0.0 3.9 5 0 0 5 5 4 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KIY44784.1 - 0.0047 16.5 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 KIY44784.1 - 0.0047 17.2 0.2 1.9 8.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY44784.1 - 0.0055 16.3 0.5 2 7.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 KIY44784.1 - 0.0059 16.7 1.0 5 7.1 0.3 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain PRK PF00485.18 KIY44784.1 - 0.0075 16.0 0.0 2.8 7.6 0.0 2.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KIY44784.1 - 0.01 16.3 0.0 6.1 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIY44784.1 - 0.013 15.6 0.0 9.2 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIY44784.1 - 0.025 15.1 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIY44784.1 - 0.044 13.9 0.0 18 5.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 KIY44784.1 - 0.046 12.9 0.0 9.4 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KIY44784.1 - 0.054 13.4 0.0 0.85 9.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KIY44784.1 - 0.062 13.7 0.0 7 7.1 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 KIY44784.1 - 0.077 12.7 0.2 7.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KIY44784.1 - 0.084 13.3 0.1 26 5.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIY44784.1 - 0.11 11.7 0.0 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Dendrin PF15498.6 KIY44785.1 - 0.024 13.4 0.9 0.027 13.2 0.9 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin ABC_tran PF00005.27 KIY44786.1 - 5.6e-34 117.6 0.0 9.9e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY44786.1 - 1.2e-07 31.5 0.1 5.1e-06 26.1 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY44786.1 - 6.7e-05 22.8 0.0 0.0076 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY44786.1 - 9.6e-05 22.8 0.1 0.00021 21.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 KIY44786.1 - 0.0003 19.7 0.0 0.0005 19.0 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 KIY44786.1 - 0.0013 19.0 0.1 0.01 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KIY44786.1 - 0.005 16.6 0.0 0.0088 15.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIY44786.1 - 0.0073 16.7 0.5 0.11 12.9 0.5 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KIY44786.1 - 0.011 16.0 0.9 0.14 12.4 0.9 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 KIY44786.1 - 0.031 13.5 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 KIY44786.1 - 0.035 13.8 0.0 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KIY44786.1 - 0.043 13.7 0.0 0.076 12.9 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KIY44786.1 - 0.054 12.8 0.0 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 KIY44786.1 - 0.092 12.5 0.1 0.4 10.4 0.0 2.1 2 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 KIY44786.1 - 0.093 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KIY44786.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KIY44786.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KIY44786.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KIY44786.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF1118 PF06549.12 KIY44787.1 - 0.00013 22.2 0.8 0.00013 22.2 0.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1118) HA2 PF04408.23 KIY44788.1 - 9e-22 77.4 0.0 9e-22 77.4 0.0 3.7 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY44788.1 - 2.4e-19 69.5 0.3 5.7e-19 68.3 0.3 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY44788.1 - 5.3e-15 55.7 0.0 1.5e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY44788.1 - 1.2e-07 31.7 0.1 4.6e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KIY44788.1 - 8.2e-05 22.4 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY44788.1 - 0.0005 20.3 0.1 0.0026 18.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY44788.1 - 0.0011 19.3 0.1 0.0038 17.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIY44788.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KIY44788.1 - 0.036 14.1 0.1 1.3 8.9 0.1 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PRiA4_ORF3 PF07929.11 KIY44789.1 - 7.2e-50 169.1 0.2 4.3e-27 94.9 0.0 2.9 2 1 0 2 2 2 2 Plasmid pRiA4b ORF-3-like protein UBD PF16455.5 KIY44789.1 - 0.16 12.2 0.0 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-binding domain BNR PF02012.20 KIY44789.1 - 0.26 11.4 3.3 3.2 8.1 0.2 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Glycos_transf_4 PF00953.21 KIY44790.1 - 4.7e-32 111.2 8.6 4.7e-32 111.2 8.6 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 4 dCMP_cyt_deam_1 PF00383.23 KIY44791.1 - 1.8e-07 30.9 0.0 5e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIY44791.1 - 4.1e-07 29.8 0.0 1.2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 MafB19-like deaminase SET PF00856.28 KIY44791.1 - 9.6e-07 29.3 0.1 1.9e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 SET domain Bd3614-deam PF14439.6 KIY44791.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase ICL PF00463.21 KIY44793.1 - 1.1e-255 849.2 0.2 1.2e-255 849.0 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KIY44793.1 - 6.1e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Phage_int_SAM_3 PF14659.6 KIY44794.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain ICL PF00463.21 KIY44795.1 - 2.2e-94 316.8 0.2 3.2e-94 316.3 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Beta_helix PF13229.6 KIY44796.1 - 8.2e-09 35.5 27.1 1e-07 32.0 12.4 2.9 2 1 2 4 4 4 2 Right handed beta helix region NosD PF05048.13 KIY44796.1 - 0.00012 21.4 11.8 0.0013 18.1 2.5 2.5 1 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) F-actin_cap_A PF01267.17 KIY44797.1 - 1e-96 323.5 0.0 1.1e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Ubie_methyltran PF01209.18 KIY44799.1 - 8.7e-76 254.3 0.0 1.1e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KIY44799.1 - 5e-14 52.8 0.0 1.2e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY44799.1 - 2.9e-11 43.8 0.0 6.2e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY44799.1 - 8.6e-10 38.7 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY44799.1 - 8.7e-10 39.2 0.0 1.6e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY44799.1 - 3.1e-09 36.8 0.0 7.9e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KIY44799.1 - 0.035 15.1 0.0 0.074 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cullin PF00888.22 KIY44800.1 - 2.7e-186 620.9 16.4 2.7e-186 620.9 16.4 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KIY44800.1 - 2.5e-27 94.7 1.6 1.2e-26 92.6 1.6 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 KIY44800.1 - 2.1 8.7 7.2 2.9 8.3 0.1 3.9 4 1 0 4 4 4 0 Penicillinase repressor Plasmid_RAQPRD PF09686.10 KIY44801.1 - 6.8 7.0 6.9 5.5 7.3 0.3 2.8 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) PQQ PF01011.21 KIY44802.1 - 0.017 15.0 0.1 0.22 11.5 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat Isy1 PF06246.12 KIY44803.1 - 5.6e-85 285.0 2.1 1e-84 284.1 2.1 1.4 1 1 0 1 1 1 1 Isy1-like splicing family HMG_box PF00505.19 KIY44804.1 - 7.2e-12 45.6 1.9 1.6e-11 44.4 1.9 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY44804.1 - 1.6e-07 31.8 0.3 5.4e-07 30.1 0.3 1.9 1 0 0 1 1 1 1 HMG-box domain Ribosom_S12_S23 PF00164.25 KIY44805.1 - 4e-30 103.8 0.2 4.5e-30 103.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Epimerase PF01370.21 KIY44806.1 - 4.8e-10 39.3 0.0 4.3e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY44806.1 - 8.6e-10 38.1 0.0 2.1e-09 36.8 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KIY44806.1 - 9.6e-10 38.4 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY44806.1 - 1e-09 38.6 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIY44806.1 - 2.2e-06 27.0 0.0 0.00023 20.3 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIY44806.1 - 0.0003 20.1 0.7 0.14 11.3 0.6 2.5 1 1 1 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIY44806.1 - 0.021 14.3 0.0 0.086 12.2 0.0 1.8 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIY44806.1 - 0.027 13.9 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF2462 PF09495.10 KIY44807.1 - 4.4e-22 78.6 12.6 5.2e-22 78.4 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) PH_4 PF15404.6 KIY44808.1 - 5.9e-24 84.9 0.0 3e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Ribosomal_L36 PF00444.18 KIY44808.1 - 0.22 11.7 0.4 3.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L36 zf-Nse PF11789.8 KIY44809.1 - 3.3e-17 62.1 0.0 6.3e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KIY44809.1 - 4.3e-05 23.4 0.1 9.5e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY44809.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY44809.1 - 0.025 14.5 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.18 KIY44811.1 - 0.0011 18.1 0.0 0.29 10.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain XPB_DRD PF18458.1 KIY44811.1 - 0.23 11.4 1.2 0.74 9.7 1.2 1.9 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain Phage_integrase PF00589.22 KIY44813.1 - 0.0023 17.7 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family DUF3684 PF12449.8 KIY44813.1 - 0.0076 14.1 0.0 0.0098 13.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) NTP_transf_5 PF14907.6 KIY44815.1 - 0.0054 16.4 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DUF2605 PF10792.9 KIY44815.1 - 0.086 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Arf PF00025.21 KIY44816.1 - 7.8e-38 129.7 0.0 9.1e-38 129.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KIY44816.1 - 7.5e-19 67.9 0.0 8.6e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY44816.1 - 2.6e-14 53.5 0.0 3.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIY44816.1 - 1.8e-09 37.3 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY44816.1 - 2.8e-08 33.4 0.0 3.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY44816.1 - 1.4e-05 25.1 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KIY44816.1 - 5.1e-05 22.6 0.4 0.00071 18.8 0.1 2.1 1 1 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 KIY44816.1 - 0.0023 18.0 0.0 0.15 12.1 0.2 2.3 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 KIY44816.1 - 0.012 15.1 0.0 0.02 14.5 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KIY44816.1 - 0.03 14.1 0.2 2.1 8.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KIY44816.1 - 0.092 12.3 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RPN13_C PF16550.5 KIY44817.1 - 2.6e-25 88.8 1.7 3e-25 88.6 0.2 1.8 2 0 0 2 2 2 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KIY44817.1 - 2.8e-24 85.5 0.0 4.1e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor GST_N_3 PF13417.6 KIY44818.1 - 6.7e-18 64.9 0.1 1.1e-17 64.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY44818.1 - 7.9e-18 64.6 0.0 1.4e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY44818.1 - 5.4e-14 52.2 0.0 8.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY44818.1 - 3.5e-12 46.4 0.0 6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY44818.1 - 3e-06 27.3 0.0 6.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY44818.1 - 5.6e-05 23.1 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_S32 PF05579.13 KIY44819.1 - 0.0051 16.0 0.1 0.0085 15.3 0.1 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.6 KIY44819.1 - 0.006 17.5 0.3 0.44 11.4 0.2 3.3 2 1 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.21 KIY44819.1 - 0.024 14.5 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S3 PF00944.19 KIY44819.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Alphavirus core protein Peroxin-13_N PF04088.13 KIY44820.1 - 1.2e-43 148.8 0.1 1.8e-43 148.3 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 KIY44820.1 - 1.7e-10 40.3 0.7 0.00018 21.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KIY44820.1 - 1.2e-09 37.7 0.0 2.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIY44820.1 - 7.5e-08 32.1 0.1 1.4e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Lamprin PF06403.11 KIY44820.1 - 0.016 15.1 7.3 0.025 14.6 7.3 1.3 1 0 0 1 1 1 0 Lamprin Pex2_Pex12 PF04757.14 KIY44820.1 - 0.074 12.6 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region SET PF00856.28 KIY44821.1 - 1.1e-13 51.9 2.3 2e-13 51.1 0.3 2.3 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 KIY44821.1 - 8.3e-07 29.4 12.8 8.3e-07 29.4 12.8 3.8 3 1 0 3 3 3 1 CXC domain MSL2-CXC PF16682.5 KIY44821.1 - 4.8e-06 26.6 14.4 4.8e-06 26.6 14.4 2.8 1 1 1 2 2 2 1 CXC domain of E3 ubiquitin-protein ligase MSL2 HAT_KAT11 PF08214.11 KIY44822.1 - 2e-38 132.6 0.0 2.6e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein DASH_Spc19 PF08287.11 KIY44823.1 - 0.0045 16.9 1.2 0.16 11.9 0.2 2.4 2 0 0 2 2 2 1 Spc19 Phasin PF05597.11 KIY44823.1 - 0.12 12.3 2.2 0.092 12.8 0.4 1.6 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CorA PF01544.18 KIY44823.1 - 0.19 11.0 0.6 0.3 10.4 0.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Spc7 PF08317.11 KIY44823.1 - 0.48 9.2 3.9 0.7 8.7 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Fcf2 PF08698.11 KIY44824.1 - 2.5e-29 101.5 0.0 7.9e-29 99.9 0.0 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing DNA_pol_phi PF04931.13 KIY44824.1 - 0.82 7.7 6.8 1.1 7.3 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KIY44824.1 - 8.9 6.0 17.7 0.034 13.9 7.7 2.0 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein D123 PF07065.14 KIY44826.1 - 2.2e-89 299.7 0.0 2.5e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 D123 His_Phos_2 PF00328.22 KIY44827.1 - 4e-44 151.5 0.0 5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sas10 PF09368.10 KIY44828.1 - 8.7e-23 80.6 3.3 8.7e-23 80.6 3.3 3.3 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KIY44828.1 - 1.6e-05 25.5 0.1 1.6e-05 25.5 0.1 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family GTP_CH_N PF12471.8 KIY44829.1 - 2.4e-88 294.9 0.0 3.7e-88 294.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KIY44829.1 - 3.2e-15 56.1 0.0 4.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF2205 PF10224.9 KIY44830.1 - 1.7e-10 40.8 0.1 1.7e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 KIY44830.1 - 0.022 15.4 0.3 0.024 15.2 0.3 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Trimer_CC PF08954.11 KIY44830.1 - 0.13 11.9 0.6 0.13 11.9 0.6 1.6 2 0 0 2 2 2 0 Trimerisation motif NAD_binding_4 PF07993.12 KIY44831.1 - 3e-26 92.2 0.0 4.5e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIY44831.1 - 1.2e-22 80.1 0.0 1e-21 77.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KIY44831.1 - 7.6e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY44831.1 - 3.3e-06 27.3 0.0 1.2e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KIY44831.1 - 0.076 12.9 0.2 0.35 10.8 0.1 2.2 2 1 0 2 2 2 0 KR domain Baculo_PEP_C PF04513.12 KIY44832.1 - 0.0023 18.0 17.9 0.0034 17.4 5.5 2.1 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus RPAP1_N PF08621.10 KIY44833.1 - 0.0022 17.7 0.9 0.0034 17.1 0.9 1.3 1 0 0 1 1 1 1 RPAP1-like, N-terminal CxC2 PF18803.1 KIY44835.1 - 3.9e-27 94.5 0.0 5e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY44835.1 - 4.1e-05 23.7 0.0 4.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY44835.1 - 0.0046 16.8 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases NmrA PF05368.13 KIY44836.1 - 1.1e-33 116.7 0.0 1.6e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY44836.1 - 3e-12 46.8 0.0 4.5e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY44836.1 - 5.1e-05 22.8 0.0 8.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY44836.1 - 0.029 13.4 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KIY44836.1 - 0.095 12.1 0.0 0.28 10.6 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KIY44836.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Suf PF05843.14 KIY44838.1 - 1e-56 193.1 10.7 1.4e-56 192.6 0.4 4.4 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KIY44838.1 - 5.7e-09 36.1 1.1 0.024 15.5 0.0 6.5 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY44838.1 - 1.9e-05 25.0 5.7 0.29 11.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY44838.1 - 2.1e-05 24.9 0.6 0.98 10.0 0.2 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY44838.1 - 0.00013 22.6 1.6 8.3 7.2 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIY44838.1 - 0.00041 19.6 4.5 0.16 11.1 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_18 PF13512.6 KIY44838.1 - 0.0025 17.9 5.1 0.066 13.3 0.2 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KIY44838.1 - 0.0098 15.9 12.4 0.51 10.3 0.3 4.1 4 1 0 4 4 4 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 KIY44838.1 - 0.18 12.0 5.2 5.1 7.5 0.0 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat STE3 PF02076.15 KIY44839.1 - 4.4e-104 347.8 17.2 5e-104 347.6 17.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor MBD PF01429.19 KIY44839.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyl-CpG binding domain Mito_carr PF00153.27 KIY44840.1 - 3.4e-47 158.3 0.8 2.1e-22 78.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NmrA PF05368.13 KIY44842.1 - 2e-34 119.2 0.0 2.6e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY44842.1 - 8.8e-15 55.1 0.2 3.9e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KIY44842.1 - 0.00055 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KIY44842.1 - 0.041 13.3 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase APH PF01636.23 KIY44843.1 - 8.8e-05 22.5 0.0 0.00022 21.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY44843.1 - 0.00054 19.6 0.0 0.0009 18.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIY44843.1 - 0.016 14.5 0.2 0.026 13.9 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIY44843.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain zf-C2H2 PF00096.26 KIY44844.1 - 6.2e-13 48.4 12.7 1.3e-07 31.7 1.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY44844.1 - 3.9e-11 42.8 10.3 2.1e-06 28.1 1.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY44844.1 - 3.6e-09 36.6 17.5 1.7e-08 34.5 4.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIY44844.1 - 2e-07 30.8 7.1 6.8e-07 29.1 0.3 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY44844.1 - 2.2e-07 31.0 4.1 9.6e-05 22.6 0.1 2.4 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY44844.1 - 5.8e-07 29.7 3.1 4.7e-05 23.6 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KIY44844.1 - 3.6e-05 24.0 3.4 5.5e-05 23.4 3.4 1.3 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KIY44844.1 - 8.7e-05 22.9 8.2 0.016 15.6 1.9 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 KIY44844.1 - 0.00044 20.2 2.5 0.021 14.8 0.2 2.2 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_8 PF15909.5 KIY44844.1 - 0.00084 19.6 3.1 0.001 19.3 3.1 1.0 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KIY44844.1 - 0.0014 18.9 3.1 0.04 14.3 0.3 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KIY44844.1 - 0.0015 18.3 2.6 0.005 16.6 0.4 1.9 1 1 1 2 2 2 1 GAGA factor zf-C2H2_9 PF16293.5 KIY44844.1 - 0.0029 17.4 1.0 0.074 12.9 0.1 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KIY44844.1 - 0.0036 17.7 0.6 0.0036 17.7 0.6 2.8 2 2 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_aberr PF17017.5 KIY44844.1 - 0.0073 16.5 1.1 0.029 14.5 0.1 1.9 1 1 1 2 2 2 1 Aberrant zinc-finger Prok-RING_4 PF14447.6 KIY44844.1 - 0.029 14.2 0.6 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-H2C2_5 PF13909.6 KIY44844.1 - 0.06 13.1 12.0 0.35 10.7 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KIY44844.1 - 0.1 12.3 2.2 5.3 6.8 1.5 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain PRP21_like_P PF12230.8 KIY44844.1 - 0.13 12.1 0.4 0.15 11.9 0.4 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2HC_2 PF13913.6 KIY44844.1 - 0.17 11.9 5.5 0.8 9.7 0.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF629 PF04780.12 KIY44844.1 - 0.18 10.3 2.5 0.19 10.2 1.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_11 PF16622.5 KIY44844.1 - 5 7.0 8.7 4.2 7.2 0.4 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type STE PF02200.16 KIY44845.1 - 1.1e-38 132.1 0.1 1.3e-38 131.8 0.1 1.1 1 0 0 1 1 1 1 STE like transcription factor STE PF02200.16 KIY44846.1 - 1.1e-09 38.7 0.0 1.7e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 STE like transcription factor Hydrolase_6 PF13344.6 KIY44847.1 - 4.3e-15 55.7 0.0 7.8e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY44847.1 - 1.3e-09 37.9 0.0 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIY44847.1 - 3.7e-05 24.1 0.0 0.019 15.2 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase OAD_gamma PF04277.13 KIY44848.1 - 0.52 10.9 3.3 13 6.5 0.8 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain RseC_MucC PF04246.12 KIY44848.1 - 4 7.4 5.4 0.33 10.9 0.8 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC YLP PF02757.17 KIY44849.1 - 3 8.1 6.0 0.81 9.8 0.7 2.9 2 0 0 2 2 2 0 YLP motif DTHCT PF08070.11 KIY44849.1 - 6.8 7.5 12.6 20 5.9 12.6 1.8 1 0 0 1 1 1 0 DTHCT (NUC029) region p450 PF00067.22 KIY44850.1 - 2.4e-63 214.5 0.0 3.1e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KIY44851.1 - 1.3e-30 106.7 0.0 1.7e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY44851.1 - 8.6e-08 32.3 0.0 1.6e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY44851.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Prefoldin PF02996.17 KIY44852.1 - 2e-26 92.2 1.9 1.2e-24 86.5 1.9 2.1 1 1 0 1 1 1 1 Prefoldin subunit CC2-LZ PF16516.5 KIY44852.1 - 2.5 8.5 8.1 15 6.0 0.4 2.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF2393 PF09624.10 KIY44853.1 - 0.037 14.0 3.9 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) DUF3493 PF11998.8 KIY44853.1 - 0.36 11.0 5.2 1.2 9.3 0.1 2.9 2 1 0 2 2 2 0 Low psii accumulation1 / Rep27 DUF4203 PF13886.6 KIY44853.1 - 1.3 8.6 14.0 3.5 7.2 13.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) DUF4131 PF13567.6 KIY44853.1 - 2.5 7.7 9.4 12 5.5 2.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DAD PF02109.16 KIY44854.1 - 0.019 15.2 3.1 0.068 13.5 0.0 2.5 1 1 2 3 3 3 0 DAD family PhaG_MnhG_YufB PF03334.14 KIY44854.1 - 0.07 13.4 0.5 0.07 13.4 0.5 2.6 3 0 0 3 3 3 0 Na+/H+ antiporter subunit DUF3446 PF11928.8 KIY44854.1 - 0.1 12.9 2.1 0.11 12.8 0.6 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain OAD_gamma PF04277.13 KIY44854.1 - 0.37 11.4 3.8 5.3 7.7 0.2 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DHHC PF01529.20 KIY44854.1 - 2.2 8.4 4.5 1.3 9.1 0.7 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase EAP30 PF04157.16 KIY44855.1 - 5.1e-33 114.3 0.0 7.6e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KIY44855.1 - 1.3e-19 70.1 0.0 2.4e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 KIY44855.1 - 0.0021 17.3 12.0 0.15 11.4 1.5 2.7 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KIY44855.1 - 0.0073 16.3 4.2 1.2 9.3 0.0 2.7 3 0 0 3 3 3 2 Sec23/Sec24 zinc finger MarR PF01047.22 KIY44855.1 - 0.0081 16.1 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 MarR family Vps36-NZF-N PF16988.5 KIY44855.1 - 0.017 14.5 0.6 0.017 14.5 0.6 2.7 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 KIY44855.1 - 0.018 15.1 5.6 0.062 13.3 0.4 2.3 1 1 2 3 3 3 0 Double zinc ribbon NTP_transf_3 PF12804.7 KIY44855.1 - 0.11 12.9 0.1 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain NinF PF05810.12 KIY44855.1 - 0.13 12.2 0.7 1.2 9.0 0.3 2.4 2 0 0 2 2 2 0 NinF protein IMUP PF15761.5 KIY44855.1 - 1.5 9.5 4.2 10 6.9 0.6 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein Cys_rich_CPCC PF14206.6 KIY44855.1 - 3.7 7.4 5.5 7.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPCC Tnp_zf-ribbon_2 PF13842.6 KIY44855.1 - 6.6 7.6 6.1 5.8 7.8 0.3 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon MFS_1 PF07690.16 KIY44856.1 - 2.9e-30 105.4 32.9 5.8e-30 104.4 33.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIY44856.1 - 0.00011 21.6 6.3 0.00011 21.6 6.3 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB FAM177 PF14774.6 KIY44856.1 - 0.16 12.4 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 FAM177 family STE3 PF02076.15 KIY44857.1 - 2.9e-18 66.1 7.2 3e-18 66.0 7.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor MNSV_P7B PF06692.11 KIY44857.1 - 0.52 10.4 3.4 0.58 10.2 0.4 2.0 1 1 1 2 2 2 0 Melon necrotic spot virus P7B protein RRM_1 PF00076.22 KIY44859.1 - 3.1e-56 187.1 0.5 6.7e-15 54.7 0.0 6.2 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY44859.1 - 0.00019 21.2 0.0 0.0076 16.1 0.0 3.3 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KIY44859.1 - 0.036 14.2 0.0 8.1 6.6 0.0 3.4 4 0 0 4 4 4 0 RNA recognition motif SET_assoc PF11767.8 KIY44859.1 - 0.067 12.8 0.1 26 4.6 0.0 3.4 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated ABC2_membrane PF01061.24 KIY44860.1 - 4.7e-63 212.4 55.8 6.4e-34 117.2 21.5 3.2 3 1 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KIY44860.1 - 5.6e-34 117.6 0.0 1.7e-16 61.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIY44860.1 - 1.2e-33 114.8 7.8 1.2e-29 102.0 0.1 2.9 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY44860.1 - 2.7e-14 53.5 0.0 6.5e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KIY44860.1 - 2.8e-07 30.0 34.3 2.4e-05 23.6 12.9 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KIY44860.1 - 4.3e-07 30.5 0.1 0.0085 16.5 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY44860.1 - 7.5e-07 29.2 1.3 0.00011 22.1 0.1 3.4 3 1 1 4 4 4 1 RsgA GTPase AAA_22 PF13401.6 KIY44860.1 - 9.1e-05 22.8 0.0 0.098 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KIY44860.1 - 0.00028 21.3 0.0 0.47 10.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KIY44860.1 - 0.00056 20.0 0.2 0.78 9.8 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY44860.1 - 0.00056 20.5 0.0 0.039 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY44860.1 - 0.0013 18.3 0.4 0.017 14.7 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KIY44860.1 - 0.0018 18.0 0.2 0.26 11.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KIY44860.1 - 0.0033 17.7 0.1 0.031 14.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY44860.1 - 0.012 15.8 0.0 0.9 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIY44860.1 - 0.014 15.4 0.2 1 9.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KIY44860.1 - 0.02 14.9 0.3 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KIY44860.1 - 0.023 14.4 0.8 0.79 9.4 0.3 2.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KIY44860.1 - 0.043 13.6 0.2 5.9 6.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 KIY44860.1 - 0.052 13.4 0.0 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 KIY44860.1 - 0.059 13.8 0.1 7 7.1 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KIY44860.1 - 0.061 12.7 0.0 32 3.9 0.0 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KIY44860.1 - 0.07 12.7 0.7 1 8.9 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Shikimate_DH PF01488.20 KIY44860.1 - 0.075 13.1 0.0 0.27 11.3 0.1 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Zeta_toxin PF06414.12 KIY44860.1 - 0.086 12.1 0.1 3.7 6.8 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 KIY44860.1 - 0.23 11.8 0.7 27 5.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain UDPGT PF00201.18 KIY44861.1 - 4.6e-10 38.9 0.0 6.9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIY44861.1 - 0.0048 16.9 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF202 PF02656.15 KIY44864.1 - 4.9e-06 26.9 2.5 6e-06 26.6 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF202) EF1_GNE PF00736.19 KIY44865.1 - 7.1e-32 109.5 0.7 7.1e-32 109.5 0.7 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KIY44865.1 - 1.3e-14 54.3 4.7 1.3e-14 54.3 4.7 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KIY44865.1 - 0.013 15.7 0.5 0.57 10.4 0.0 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY44865.1 - 0.03 14.4 0.0 0.17 12.0 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY44865.1 - 0.042 14.0 0.2 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ldl_recept_a PF00057.18 KIY44866.1 - 0.3 11.4 0.9 0.83 9.9 0.9 1.7 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A ATPgrasp_Ter PF15632.6 KIY44867.1 - 0.089 12.5 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon UQ_con PF00179.26 KIY44868.1 - 1.3e-37 128.6 0.0 1.6e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC1 PF03109.16 KIY44869.1 - 2.7e-25 88.8 0.0 4.5e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KIY44869.1 - 0.032 13.8 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KIY44869.1 - 0.062 12.7 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Fes1 PF08609.10 KIY44870.1 - 1.4e-22 80.3 0.8 3.4e-22 79.1 0.8 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 KIY44870.1 - 0.0066 16.6 0.0 6.3 7.4 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat SIL1 PF16782.5 KIY44870.1 - 0.0089 15.3 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT_EZ PF13513.6 KIY44870.1 - 0.026 15.0 0.1 3.3 8.3 0.1 3.0 2 1 0 2 2 2 0 HEAT-like repeat Shisa PF13908.6 KIY44871.1 - 0.12 12.6 4.0 0.17 12.1 4.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1180 PF06679.12 KIY44871.1 - 0.36 11.2 10.0 0.65 10.4 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pkinase PF00069.25 KIY44873.1 - 7.1e-10 38.7 0.0 1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIY44873.1 - 8.8e-06 25.4 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY44873.1 - 0.00028 20.9 0.0 0.00087 19.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIY44873.1 - 0.0004 19.7 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 KIY44873.1 - 0.00055 19.6 0.1 0.00089 18.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Rib_5-P_isom_A PF06026.14 KIY44873.1 - 0.099 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Pkinase_fungal PF17667.1 KIY44873.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PEMT PF04191.13 KIY44874.1 - 2.5e-30 105.0 0.8 2.5e-30 105.0 0.8 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase RRM_1 PF00076.22 KIY44875.1 - 1.8e-18 66.1 0.0 2.6e-10 40.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY44875.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 KIY44875.1 - 0.014 15.6 0.0 0.076 13.3 0.0 2.2 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DASH_Duo1 PF08651.10 KIY44876.1 - 0.15 11.9 0.1 8.4 6.2 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 Peroxidase_2 PF01328.17 KIY44877.1 - 9.2e-31 107.8 0.0 1e-29 104.4 0.0 2.1 1 1 0 1 1 1 1 Peroxidase, family 2 APH PF01636.23 KIY44878.1 - 7.7e-12 45.6 0.0 1.5e-11 44.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY44878.1 - 7.4e-07 29.0 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KIY44878.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Na_H_Exchanger PF00999.21 KIY44879.1 - 3.5e-72 243.3 34.4 4.3e-72 243.0 34.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 KIY44879.1 - 0.0051 17.2 0.0 2.9 8.3 0.0 3.1 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family 60KD_IMP PF02096.20 KIY44880.1 - 1.4e-12 47.9 0.0 1.6e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2786 PF10979.8 KIY44880.1 - 0.0095 15.8 0.2 0.017 15.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) eIF2_C PF09173.11 KIY44881.1 - 4.2e-34 116.7 0.6 9.6e-34 115.5 0.6 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KIY44881.1 - 1.1e-20 74.0 2.2 2.2e-19 69.8 2.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KIY44881.1 - 1.7e-11 44.4 1.3 3.2e-11 43.4 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KIY44881.1 - 0.0065 16.4 0.5 0.059 13.3 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KIY44881.1 - 0.011 15.8 0.8 0.022 14.8 0.1 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KIY44881.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dak1_2 PF13684.6 KIY44881.1 - 0.079 12.0 0.3 0.12 11.4 0.3 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family G-alpha PF00503.20 KIY44882.1 - 2.3e-95 319.7 0.0 2.7e-95 319.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY44882.1 - 0.0026 17.2 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KIY44882.1 - 0.046 13.1 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 KIY44882.1 - 0.069 12.4 0.1 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 KIY44882.1 - 0.1 12.8 0.0 0.93 9.7 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RasGEF PF00617.19 KIY44884.1 - 7.5e-24 84.9 0.1 1.7e-23 83.8 0.0 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KIY44884.1 - 1.5e-10 41.2 1.1 3.5e-10 40.1 1.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif ASF1_hist_chap PF04729.13 KIY44885.1 - 1.1e-65 220.3 0.0 1.3e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RRM_1 PF00076.22 KIY44886.1 - 5.4e-13 48.6 0.0 7.4e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIY44886.1 - 0.025 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 KIY44886.1 - 0.22 11.7 0.0 0.33 11.2 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain Bap31 PF05529.12 KIY44888.1 - 3.2e-41 140.3 4.0 5.7e-41 139.5 4.0 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KIY44888.1 - 5.8e-13 48.6 12.6 7.3e-13 48.3 11.0 1.9 1 1 1 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain CHD5 PF04420.14 KIY44888.1 - 0.0043 16.9 0.7 0.0096 15.8 0.7 1.7 1 0 0 1 1 1 1 CHD5-like protein TolA_bind_tri PF16331.5 KIY44888.1 - 0.012 15.7 3.1 0.023 14.8 3.1 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF4446 PF14584.6 KIY44888.1 - 0.022 14.8 0.3 0.022 14.8 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF3810 PF12725.7 KIY44888.1 - 0.031 13.6 0.9 0.035 13.4 0.9 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) TMF_DNA_bd PF12329.8 KIY44888.1 - 0.038 14.0 7.7 0.058 13.4 7.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF898 PF05987.13 KIY44888.1 - 0.046 12.8 0.6 0.052 12.6 0.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF2430 PF10353.9 KIY44888.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) MbeD_MobD PF04899.12 KIY44888.1 - 0.15 12.2 5.4 0.065 13.3 3.1 1.6 2 0 0 2 2 2 0 MbeD/MobD like DivIC PF04977.15 KIY44888.1 - 1.6 8.6 11.0 2.1 8.2 6.3 2.8 2 1 1 3 3 3 0 Septum formation initiator Ribosomal_S7 PF00177.21 KIY44889.1 - 1.1e-19 70.5 0.0 1.3e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e UCH PF00443.29 KIY44890.1 - 2.1e-32 112.6 0.0 5.4e-32 111.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY44890.1 - 6.3e-12 45.7 1.6 9.5e-10 38.6 1.6 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KIY44890.1 - 1.1e-06 28.2 0.0 3.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KIY44890.1 - 0.0017 18.8 0.0 0.015 15.7 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-like domain Glyco_hydro_115 PF15979.5 KIY44891.1 - 3.9e-132 440.8 1.8 5.5e-132 440.3 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KIY44891.1 - 4.4e-55 186.1 0.0 8.8e-55 185.2 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain SNF2_N PF00176.23 KIY44892.1 - 1e-56 192.2 0.0 1.8e-56 191.4 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY44892.1 - 1.3e-17 64.1 0.0 3e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY44892.1 - 1.7e-08 34.7 0.0 3.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KIY44892.1 - 9.9e-05 22.1 0.9 9.9e-05 22.1 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY44892.1 - 0.00011 22.1 3.8 0.0003 20.7 3.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY44892.1 - 0.00016 21.6 1.0 0.00016 21.6 1.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY44892.1 - 0.0014 18.4 1.7 0.0014 18.4 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 KIY44892.1 - 0.0027 17.0 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_2 PF13639.6 KIY44892.1 - 0.0049 17.2 2.5 0.0049 17.2 2.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KIY44892.1 - 0.014 15.5 1.1 0.014 15.5 1.1 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 KIY44892.1 - 0.084 13.0 3.0 0.19 11.9 3.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-4CXXC_R1 PF10497.9 KIY44892.1 - 0.11 12.8 7.1 0.25 11.6 4.9 2.6 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 IBR PF01485.21 KIY44892.1 - 1.3 9.3 8.9 1.3 9.3 0.2 3.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 KIY44892.1 - 2.3 8.2 10.1 1.2 9.1 4.5 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIY44892.1 - 2.4 8.0 8.9 0.54 10.1 1.4 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Oest_recep PF02159.15 KIY44893.1 - 0.013 16.0 0.2 0.015 15.8 0.2 1.1 1 0 0 1 1 1 0 Oestrogen receptor Phage_integrase PF00589.22 KIY44894.1 - 0.001 18.9 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family zf-primase PF09329.11 KIY44898.1 - 1.2e-16 60.3 1.1 2.4e-16 59.2 1.1 1.6 1 0 0 1 1 1 1 Primase zinc finger IPK PF03770.16 KIY44898.1 - 0.1 12.5 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Inositol polyphosphate kinase DUF1690 PF07956.11 KIY44898.1 - 2 8.8 7.1 4.9 7.6 3.2 2.5 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF374 PF04028.13 KIY44898.1 - 2.5 7.7 4.5 8.8 6.0 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF374) BRE1 PF08647.11 KIY44898.1 - 7.4 6.7 8.5 4.7 7.4 5.6 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase zf-RING_2 PF13639.6 KIY44899.1 - 0.0011 19.3 2.5 0.0017 18.6 2.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY44899.1 - 0.023 14.7 0.6 0.043 13.9 0.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.7 KIY44899.1 - 0.032 14.4 1.9 0.061 13.5 1.9 1.5 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 KIY44899.1 - 0.038 13.9 2.4 0.068 13.1 2.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_zinc_N PF00107.26 KIY44900.1 - 2.9e-10 40.2 0.9 5.6e-10 39.3 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY44900.1 - 3.9e-09 36.4 0.4 1.7e-08 34.3 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY44900.1 - 5.2e-07 30.8 0.1 9.1e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY44900.1 - 0.0055 16.6 0.1 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase His_Phos_2 PF00328.22 KIY44902.1 - 2.3e-46 158.9 0.0 3e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPR_2 PF13041.6 KIY44903.1 - 0.0011 19.1 0.0 11 6.3 0.0 4.4 4 2 0 4 4 4 2 PPR repeat family Pkinase PF00069.25 KIY44904.1 - 8.4e-32 110.6 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44904.1 - 2.1e-23 82.9 0.0 1.4e-22 80.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY44904.1 - 1.6e-05 24.4 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HLH PF00010.26 KIY44905.1 - 1.3e-14 53.9 0.1 2.3e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain p450 PF00067.22 KIY44906.1 - 9.7e-65 219.1 0.0 1.8e-64 218.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KIY44907.1 - 4.2e-11 42.7 0.1 2.4e-10 40.2 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY44907.1 - 1.8e-06 27.8 0.5 0.00078 19.1 0.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY44907.1 - 2.3e-06 27.7 0.1 1.1e-05 25.5 0.1 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIY44907.1 - 4.1e-06 26.9 0.2 1e-05 25.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY44907.1 - 2.4e-05 23.7 0.1 0.00081 18.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIY44907.1 - 0.00061 19.2 0.0 0.0057 16.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KIY44907.1 - 0.0011 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KIY44907.1 - 0.025 15.1 0.1 0.053 14.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY44907.1 - 0.057 12.5 0.7 0.099 11.7 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KIY44907.1 - 0.17 11.1 0.2 2.4 7.3 0.2 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lsr2 PF11774.8 KIY44907.1 - 1.2 9.3 3.5 2.2 8.5 1.4 2.1 2 0 0 2 2 2 0 Lsr2 OTU PF02338.19 KIY44909.1 - 4.4e-14 53.1 0.0 7.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_M54 PF07998.11 KIY44910.1 - 6.1e-09 36.1 0.1 1.2e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_4 PF13583.6 KIY44910.1 - 0.063 12.9 0.5 0.18 11.4 0.8 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KIY44910.1 - 0.09 12.6 0.4 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 Matrixin Metallopep PF12044.8 KIY44910.1 - 0.12 11.0 0.2 0.18 10.4 0.2 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.9 KIY44910.1 - 0.13 11.2 0.5 0.2 10.6 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 KIY44910.1 - 0.14 12.7 1.2 0.24 11.9 0.9 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like PP28 PF10252.9 KIY44912.1 - 1.3e-25 89.6 14.6 1.3e-25 89.6 14.6 3.1 2 2 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 SDA1 PF05285.12 KIY44912.1 - 0.064 12.7 37.0 0.082 12.3 37.0 1.1 1 0 0 1 1 1 0 SDA1 Catalase PF00199.19 KIY44913.1 - 7e-187 621.2 0.1 8.6e-187 620.9 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIY44913.1 - 2.2e-14 53.4 0.0 6.1e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive p450 PF00067.22 KIY44914.1 - 3.3e-67 227.2 0.0 3.9e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S6e PF01092.19 KIY44917.1 - 7.4e-28 97.0 0.0 1.1e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e Pkinase PF00069.25 KIY44918.1 - 1.3e-13 50.9 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44918.1 - 2.3e-06 27.1 0.0 4.3e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY44918.1 - 0.029 13.2 0.0 0.068 11.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Amnionless PF14828.6 KIY44920.1 - 9.9e-05 21.3 0.7 0.00016 20.6 0.1 1.6 1 1 0 2 2 2 1 Amnionless Utp14 PF04615.13 KIY44920.1 - 2.9 6.4 5.1 4 5.9 5.1 1.2 1 0 0 1 1 1 0 Utp14 protein RVT_1 PF00078.27 KIY44924.1 - 2.1e-05 24.2 0.0 6e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A3 PF02160.15 KIY44924.1 - 0.12 11.9 0.1 0.69 9.4 0.0 1.8 1 1 1 2 2 2 0 Cauliflower mosaic virus peptidase (A3) zf-RVT PF13966.6 KIY44925.1 - 2.3e-05 25.0 0.5 8.3e-05 23.2 0.5 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Ldh_1_N PF00056.23 KIY44927.1 - 9.4e-40 136.0 0.3 1.5e-39 135.3 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KIY44927.1 - 4e-38 131.0 0.0 5.7e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KIY44927.1 - 0.0004 19.5 0.0 0.00075 18.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KIY44927.1 - 0.0023 17.5 0.3 0.45 10.1 0.1 2.4 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.19 KIY44927.1 - 0.065 12.5 2.1 1.6 8.0 0.2 3.1 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Chitin_synth_2 PF03142.15 KIY44928.1 - 2.9e-230 765.4 0.0 3.7e-230 765.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KIY44928.1 - 4.4e-47 160.7 0.0 1.4e-40 139.3 0.0 3.8 3 1 0 3 3 3 2 Myosin head (motor domain) DEK_C PF08766.11 KIY44928.1 - 4.8e-17 61.6 0.1 9.9e-17 60.6 0.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain Cyt-b5 PF00173.28 KIY44928.1 - 2e-15 56.7 0.2 4.9e-10 39.4 0.1 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KIY44928.1 - 4e-15 56.3 0.0 2e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIY44928.1 - 4.2e-15 56.2 1.9 1.3e-14 54.6 1.9 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KIY44928.1 - 3.1e-06 27.1 0.0 0.004 17.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIY44928.1 - 0.0016 17.9 0.0 0.018 14.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Pkinase PF00069.25 KIY44929.1 - 1.3e-06 28.0 0.0 7.5e-06 25.5 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY44929.1 - 0.0026 17.1 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HSP70 PF00012.20 KIY44930.1 - 3.2e-259 861.2 3.8 3.7e-259 861.0 3.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY44930.1 - 6.4e-18 64.6 1.0 7.2e-17 61.2 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KIY44930.1 - 0.0017 17.4 0.5 0.056 12.4 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Zincin_2 PF10103.9 KIY44930.1 - 0.043 13.1 0.0 7.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Zincin-like metallopeptidase StbA PF06406.11 KIY44930.1 - 0.076 12.2 0.8 2.3 7.4 0.1 2.3 1 1 1 2 2 2 0 StbA protein RGS12_us2 PF16611.5 KIY44930.1 - 0.094 13.1 1.3 0.32 11.4 0.2 2.4 2 0 0 2 2 2 0 Unstructured region between RBD and GoLoco Hydantoinase_A PF01968.18 KIY44930.1 - 0.12 11.6 2.5 0.45 9.7 0.2 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase QslA_E PF18226.1 KIY44930.1 - 0.14 12.1 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 LasR-specific antiactivator QslA chain E HBS1_N PF08938.10 KIY44930.1 - 1.4 9.3 5.7 2.2 8.6 1.9 2.9 2 1 0 2 2 2 0 HBS1 N-terminus Spectrin PF00435.21 KIY44930.1 - 4.9 7.7 5.1 55 4.3 0.8 3.1 2 1 1 3 3 3 0 Spectrin repeat RT_RNaseH PF17917.1 KIY44933.1 - 1.5e-05 25.2 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KIY44933.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase CDP-OH_P_transf PF01066.21 KIY44937.1 - 1.2e-14 54.8 1.4 1.2e-14 54.8 1.4 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PACT_coil_coil PF10495.9 KIY44938.1 - 1.1e-14 54.8 3.5 2.3e-14 53.7 0.4 3.5 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein ABC_tran_CTD PF16326.5 KIY44938.1 - 0.0081 16.4 5.3 0.0081 16.4 5.3 10.8 6 4 4 11 11 11 2 ABC transporter C-terminal domain Ssu72 PF04722.13 KIY44938.1 - 2.8 7.4 7.7 1.1 8.8 0.4 3.2 3 0 0 3 3 3 0 Ssu72-like protein Bcr-Abl_Oligo PF09036.10 KIY44938.1 - 6.8 6.8 17.6 1.6 8.8 0.5 7.0 5 1 1 7 7 7 0 Bcr-Abl oncoprotein oligomerisation domain BIR PF00653.21 KIY44939.1 - 3.1e-22 79.0 1.0 1.7e-21 76.6 0.2 2.1 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain SIR2 PF02146.17 KIY44940.1 - 1.3e-50 171.8 0.0 1.6e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family CNH PF00780.22 KIY44941.1 - 5.7e-74 249.2 0.0 9e-74 248.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KIY44941.1 - 6e-33 114.6 0.0 1e-32 113.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KIY44941.1 - 2.5e-29 102.1 0.0 4.6e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KIY44941.1 - 5.7e-14 51.9 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KIY44941.1 - 0.062 13.1 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Neuraminidase PF18413.1 KIY44942.1 - 0.14 11.8 2.2 0.16 11.6 2.2 1.2 1 0 0 1 1 1 0 Neuraminidase-like domain Ferlin_C PF16165.5 KIY44942.1 - 0.19 11.7 1.4 0.22 11.5 1.4 1.2 1 0 0 1 1 1 0 Ferlin C-terminus HECT PF00632.25 KIY44943.1 - 2.6e-79 266.9 0.0 3.9e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KIY44943.1 - 0.0066 16.5 1.6 0.075 13.1 0.0 3.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat UIM PF02809.20 KIY44943.1 - 0.15 12.0 2.0 0.54 10.3 2.0 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Pterin_4a PF01329.19 KIY44944.1 - 4.3e-09 36.4 0.0 1.3e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase eIF3g PF12353.8 KIY44944.1 - 0.2 12.0 5.2 5.1 7.5 1.3 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G ADIP PF11559.8 KIY44945.1 - 4.2e-23 82.1 7.8 4.2e-23 82.1 7.8 3.3 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding AIP3 PF03915.13 KIY44945.1 - 0.042 13.0 7.0 0.097 11.7 7.0 1.6 1 0 0 1 1 1 0 Actin interacting protein 3 zf-HC5HC2H_2 PF13832.6 KIY44946.1 - 1.7e-17 63.6 3.8 1.7e-17 63.6 3.8 3.9 3 1 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KIY44946.1 - 3.6e-13 49.6 1.9 3.6e-13 49.6 1.9 4.3 3 1 0 3 3 3 1 PHD-like zinc-binding domain BAH PF01426.18 KIY44946.1 - 2e-10 40.6 0.0 4.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KIY44946.1 - 1e-07 31.7 22.0 2.7e-07 30.4 12.0 5.7 7 1 0 7 7 7 3 PHD-finger GATA PF00320.27 KIY44946.1 - 0.00044 19.8 4.4 0.00044 19.8 4.4 4.3 5 0 0 5 5 5 1 GATA zinc finger Myb_DNA-binding PF00249.31 KIY44946.1 - 0.0019 18.3 0.1 0.0044 17.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 KIY44946.1 - 0.0097 16.2 27.5 0.31 11.4 0.8 5.8 5 0 0 5 5 5 3 C1 domain PHD_2 PF13831.6 KIY44946.1 - 0.013 15.1 2.4 0.013 15.1 2.4 6.8 6 1 0 6 6 6 0 PHD-finger AT_hook PF02178.19 KIY44946.1 - 0.68 10.0 6.1 2.3 8.4 6.1 2.0 1 0 0 1 1 1 0 AT hook motif UCH PF00443.29 KIY44947.1 - 2e-67 227.4 0.1 2.9e-67 226.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY44947.1 - 1.3e-19 71.0 0.0 4.7e-19 69.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.29 KIY44948.1 - 4.6e-96 318.3 0.0 7e-47 159.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY44948.1 - 7.7e-27 92.8 6.7 4.4e-13 48.8 0.8 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KIY44948.1 - 4.4e-20 71.7 0.4 2.3e-19 69.4 0.5 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KIY44948.1 - 1.6e-13 50.7 0.0 1.7e-05 24.7 0.0 2.9 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KIY44948.1 - 1.2e-12 48.3 0.0 1.2e-06 28.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KIY44948.1 - 5.8e-12 46.0 0.0 5.3e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KIY44948.1 - 2.9e-11 43.0 0.0 6.2e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KIY44948.1 - 3.1e-11 43.4 0.2 0.0001 22.3 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY44948.1 - 8.5e-11 42.5 0.1 0.00061 20.2 0.0 4.3 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.13 KIY44948.1 - 2.3e-09 36.9 0.1 0.0023 17.2 0.0 2.6 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KIY44948.1 - 6.5e-09 36.2 0.2 0.022 15.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KIY44948.1 - 8.2e-08 31.9 0.4 0.0054 16.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIY44948.1 - 1.9e-07 31.7 0.0 0.0075 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIY44948.1 - 3.6e-07 30.1 0.0 0.019 14.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 KIY44948.1 - 3.9e-07 30.0 0.5 1.2e-05 25.2 0.1 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 KIY44948.1 - 8.7e-07 28.7 0.4 0.27 10.8 0.0 3.5 2 1 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 KIY44948.1 - 1.5e-06 28.5 0.0 0.022 15.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 KIY44948.1 - 1.6e-06 27.8 0.0 0.01 15.4 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KIY44948.1 - 2.8e-06 27.4 0.0 0.18 11.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 KIY44948.1 - 6e-06 25.5 0.1 0.0055 15.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KIY44948.1 - 6.2e-06 25.6 0.0 0.0036 16.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KIY44948.1 - 8.2e-06 26.1 0.0 0.067 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KIY44948.1 - 2.3e-05 24.2 0.1 0.17 11.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 KIY44948.1 - 2.5e-05 24.8 0.0 0.096 13.2 0.0 3.5 2 1 0 2 2 2 1 ABC transporter ATPase PF06745.13 KIY44948.1 - 2.7e-05 23.6 0.2 0.97 8.7 0.0 3.4 3 0 0 3 3 3 2 KaiC Sigma54_activat PF00158.26 KIY44948.1 - 7.2e-05 22.6 0.0 0.37 10.5 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 KIY44948.1 - 0.00012 22.5 0.0 1.1 9.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KIY44948.1 - 0.00013 22.0 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 KIY44948.1 - 0.00015 21.7 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KIY44948.1 - 0.00017 21.1 0.3 0.66 9.4 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 KIY44948.1 - 0.0002 21.2 0.2 0.36 10.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KIY44948.1 - 0.00025 21.0 0.0 0.97 9.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_3 PF07726.11 KIY44948.1 - 0.00032 20.6 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIY44948.1 - 0.00063 19.7 0.1 0.21 11.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain ATPase_2 PF01637.18 KIY44948.1 - 0.00083 19.3 0.2 2.7 7.9 0.0 3.6 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KIY44948.1 - 0.0011 18.7 0.5 1.4 8.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain UFD1 PF03152.14 KIY44948.1 - 0.002 17.6 0.0 0.0045 16.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Viral_helicase1 PF01443.18 KIY44948.1 - 0.0021 17.9 0.0 0.15 11.8 0.0 2.8 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KIY44948.1 - 0.0026 17.0 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KIY44948.1 - 0.0031 16.8 0.0 2 7.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.6 KIY44948.1 - 0.0036 17.6 1.8 2.8 8.2 0.0 3.7 4 1 1 5 5 3 1 AAA domain T2SSE PF00437.20 KIY44948.1 - 0.0083 15.2 0.0 0.31 10.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein KAP_NTPase PF07693.14 KIY44948.1 - 0.0087 15.3 0.0 0.17 11.1 0.0 2.5 2 1 0 3 3 3 1 KAP family P-loop domain NB-ARC PF00931.22 KIY44948.1 - 0.0099 15.1 0.0 0.53 9.4 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activ_2 PF14532.6 KIY44948.1 - 0.011 15.8 0.0 10 6.2 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 KIY44948.1 - 0.02 14.3 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 KIY44948.1 - 0.027 14.2 0.0 4.3 7.0 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 KIY44948.1 - 0.059 12.3 0.0 5.8 5.7 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase NTPase_1 PF03266.15 KIY44948.1 - 0.06 13.3 1.4 3.6 7.5 0.0 3.5 4 0 0 4 4 3 0 NTPase Molydop_binding PF01568.21 KIY44948.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Hydin_ADK PF17213.3 KIY44948.1 - 0.12 12.6 1.5 20 5.4 0.0 3.7 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain PIF1 PF05970.14 KIY44948.1 - 0.13 11.4 0.1 7 5.7 0.0 3.4 4 0 0 4 4 4 0 PIF1-like helicase AAA_6 PF12774.7 KIY44948.1 - 0.19 10.7 0.1 11 4.9 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region KH_1 PF00013.29 KIY44950.1 - 5.3e-10 39.0 0.6 1.7e-06 27.7 0.1 2.6 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.19 KIY44950.1 - 0.054 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein Mt_ATP-synt_B PF05405.14 KIY44951.1 - 6.8e-44 149.4 8.4 8.2e-44 149.1 8.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.11 KIY44951.1 - 0.0062 16.6 0.8 0.0091 16.1 0.8 1.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1539) DUF5623 PF18536.1 KIY44951.1 - 0.017 15.4 1.3 0.043 14.1 1.0 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF5623) Sec1 PF00995.23 KIY44952.1 - 1.4e-125 420.8 0.0 1.6e-125 420.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family WAPL PF07814.13 KIY44953.1 - 2.2e-12 46.5 1.9 1.1e-09 37.5 0.0 3.8 3 1 0 3 3 3 3 Wings apart-like protein regulation of heterochromatin Peptidase_C50 PF03568.17 KIY44954.1 - 4e-130 434.5 0.0 1.3e-129 432.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 KIY44954.1 - 0.00038 20.7 22.1 0.00052 20.2 4.2 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat CHAT PF12770.7 KIY44954.1 - 0.00083 18.8 0.0 0.043 13.2 0.0 3.1 2 1 0 2 2 2 1 CHAT domain TPR_8 PF13181.6 KIY44954.1 - 0.0035 17.4 0.2 17 5.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIY44954.1 - 0.013 15.4 1.9 0.18 11.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY44954.1 - 0.017 15.2 5.6 29 5.1 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 KIY44954.1 - 2 8.1 6.2 1.4 8.6 3.8 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain GTP_CH_N PF12471.8 KIY44955.1 - 2.5e-88 294.9 0.0 3.6e-88 294.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KIY44955.1 - 9.8e-16 57.8 0.0 1.7e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II Allexi_40kDa PF05549.11 KIY44955.1 - 0.1 12.1 0.8 0.17 11.4 0.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Snapin_Pallidin PF14712.6 KIY44955.1 - 0.11 12.9 2.4 0.19 12.2 2.4 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Ribosomal_S4e PF00900.20 KIY44956.1 - 1.2e-35 121.3 0.1 2.2e-35 120.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KIY44956.1 - 4e-26 90.4 0.1 7.3e-26 89.6 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KIY44956.1 - 1.5e-21 76.2 4.8 9e-21 73.7 6.1 1.7 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 KIY44956.1 - 9.3e-08 31.7 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KIY44956.1 - 2.8e-06 27.1 4.9 9e-06 25.5 4.9 1.9 1 0 0 1 1 1 1 KOW motif TPT PF03151.16 KIY44957.1 - 6.5e-55 186.5 22.3 7.9e-55 186.2 22.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIY44957.1 - 7.8e-12 45.5 36.2 4.5e-08 33.3 12.0 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KIY44957.1 - 4.2e-05 22.9 23.4 5.7e-05 22.5 23.4 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KIY44957.1 - 0.0055 15.9 1.8 0.041 13.0 0.1 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter PUNUT PF16913.5 KIY44957.1 - 6.4 5.9 23.6 75 2.4 23.6 2.1 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport SRF-TF PF00319.18 KIY44959.1 - 2.5e-17 62.1 0.0 4.8e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Apt1 PF10351.9 KIY44959.1 - 0.11 11.4 6.8 0.14 11.0 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KIY44959.1 - 0.13 11.4 10.5 0.17 11.0 10.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CDC45 PF02724.14 KIY44959.1 - 0.33 9.2 4.5 0.47 8.7 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 KIY44959.1 - 0.66 8.5 3.1 0.77 8.2 3.1 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 KIY44959.1 - 1.2 7.9 5.1 1.6 7.4 5.1 1.2 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 KIY44959.1 - 2.6 7.4 3.9 3.8 6.8 3.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4551 PF15087.6 KIY44959.1 - 3.7 6.3 6.6 4.7 5.9 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3402 PF11882.8 KIY44959.1 - 5.8 5.9 8.2 12 4.9 8.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3402) WD40 PF00400.32 KIY44960.1 - 3e-64 211.4 29.8 1.4e-09 38.4 0.1 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY44960.1 - 7.6e-23 80.6 1.2 0.0015 18.7 0.0 6.4 3 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KIY44960.1 - 2.1e-09 37.8 0.0 3.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 KIY44960.1 - 3.4e-06 26.2 0.0 0.24 10.3 0.0 4.3 4 2 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIY44960.1 - 0.00024 19.9 7.8 0.8 8.3 0.1 4.5 3 2 1 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIY44960.1 - 0.0021 16.6 0.0 0.0037 15.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain IKI3 PF04762.12 KIY44960.1 - 0.0073 14.4 0.4 0.038 12.0 0.0 1.9 2 0 0 2 2 2 1 IKI3 family TFIIIC_delta PF12657.7 KIY44960.1 - 0.036 14.0 0.4 7.9 6.4 0.0 3.2 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Nucleoporin_N PF08801.11 KIY44960.1 - 0.051 12.3 0.0 4.3 6.0 0.0 3.0 3 0 0 3 3 3 0 Nup133 N terminal like PQQ_3 PF13570.6 KIY44960.1 - 0.071 13.6 0.8 9.2 6.9 0.4 3.7 3 2 0 3 3 3 0 PQQ-like domain Frtz PF11768.8 KIY44960.1 - 0.079 11.3 0.0 3.2 6.0 0.0 2.7 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Pirin PF02678.16 KIY44961.1 - 1.5e-24 86.1 2.3 2.5e-24 85.3 2.3 1.4 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 KIY44961.1 - 1.6e-05 24.9 0.0 0.00021 21.4 0.0 2.6 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 KIY44961.1 - 0.00038 20.1 3.8 0.0012 18.5 0.3 2.7 3 0 0 3 3 3 1 Cupin domain Zn_clus PF00172.18 KIY44963.1 - 7.5e-06 26.0 7.5 7.5e-06 26.0 7.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S3Ae PF01015.18 KIY44963.1 - 0.00088 18.9 0.1 0.0018 17.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal S3Ae family F-box-like PF12937.7 KIY44964.1 - 5e-05 23.1 0.3 0.00023 21.0 0.3 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY44964.1 - 0.00011 22.0 0.2 0.00052 19.8 0.2 2.3 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 KIY44966.1 - 9.3e-31 107.0 40.3 1.2e-28 100.1 35.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavin_Reduct PF01613.18 KIY44967.1 - 1.7e-29 102.8 0.1 2.3e-29 102.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain eIF-3_zeta PF05091.12 KIY44968.1 - 7.5e-203 675.2 0.0 8.5e-203 675.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 KIY44968.1 - 0.036 13.6 0.0 7.1 6.1 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Paf1 PF03985.13 KIY44969.1 - 3.3e-64 217.5 0.0 5.4e-64 216.8 0.0 1.3 1 1 0 1 1 1 1 Paf1 Ras PF00071.22 KIY44970.1 - 9.9e-45 152.0 0.1 1.1e-44 151.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY44970.1 - 2.7e-15 56.6 0.0 4.2e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY44970.1 - 2.7e-05 23.7 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY44970.1 - 0.00025 21.1 0.0 0.00047 20.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY44970.1 - 0.0011 18.9 0.0 0.55 10.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 KIY44970.1 - 0.0012 18.9 0.1 0.0018 18.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KIY44970.1 - 0.0071 15.9 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KIY44970.1 - 0.017 15.0 0.2 0.025 14.5 0.2 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mannosidase_ig PF17786.1 KIY44971.1 - 3.6e-16 59.5 0.1 1.1e-15 57.9 0.1 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KIY44971.1 - 4.2e-07 29.6 0.0 1.3e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KIY44971.1 - 1.2e-06 29.1 0.0 3.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KIY44971.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain SWM_repeat PF13753.6 KIY44971.1 - 0.13 12.4 1.1 42 4.4 0.2 3.4 3 0 0 3 3 3 0 Putative flagellar system-associated repeat Ribosomal_L37ae PF01780.19 KIY44972.1 - 3.8e-42 142.2 10.2 4.3e-42 142.1 10.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KIY44972.1 - 0.0011 19.0 2.1 0.0016 18.6 2.1 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KIY44972.1 - 0.01 15.8 2.0 0.016 15.1 2.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-FCS PF06467.14 KIY44972.1 - 0.034 14.1 1.8 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif A2L_zn_ribbon PF08792.10 KIY44972.1 - 0.14 11.9 3.4 5.7 6.8 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.15 KIY44972.1 - 0.19 11.8 4.1 5.6 7.1 0.3 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 KIY44972.1 - 0.35 11.2 2.5 1.1 9.6 2.5 1.8 1 1 0 1 1 1 0 C1 domain zf-H2C2_2 PF13465.6 KIY44972.1 - 0.55 10.8 4.0 2.8 8.5 0.7 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Nha1_C PF08619.10 KIY44973.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus WD40 PF00400.32 KIY44974.1 - 3.4e-08 34.0 1.0 0.0074 17.1 0.3 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat MKT1_C PF12246.8 KIY44975.1 - 4.5e-70 235.6 0.0 6.7e-69 231.8 0.0 2.1 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KIY44975.1 - 5.9e-28 97.1 0.0 1.3e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KIY44975.1 - 2.8e-05 24.5 0.0 6.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIY44975.1 - 0.00027 21.2 0.0 0.00094 19.5 0.0 1.9 2 0 0 2 2 2 1 XPG I-region zf-met PF12874.7 KIY44976.1 - 0.0011 19.3 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY44976.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KIY44976.1 - 0.016 15.6 0.1 0.041 14.3 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY44976.1 - 0.044 14.6 0.2 0.12 13.3 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf_C2H2_10 PF18414.1 KIY44976.1 - 0.063 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger O-FucT PF10250.9 KIY44977.1 - 2.8e-06 27.3 0.0 4.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SLD3 PF08639.10 KIY44978.1 - 4.1e-17 62.1 1.2 6e-17 61.6 1.2 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 RhoGEF PF00621.20 KIY44979.1 - 2.1e-35 122.6 0.0 3.1e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 KIY44979.1 - 3.3e-17 62.4 9.2 5.6e-17 61.6 9.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KIY44979.1 - 0.087 13.3 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 PH domain DUF1729 PF08354.10 KIY44980.1 - 0.19 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Anoctamin PF04547.12 KIY44981.1 - 1.5e-100 337.2 2.7 1.8e-100 336.9 2.7 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Ribosomal_60s PF00428.19 KIY44982.1 - 1.8e-26 92.6 9.5 2.3e-26 92.2 9.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KIY44982.1 - 0.21 10.0 1.2 0.29 9.6 1.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein ArAE_2 PF10334.9 KIY44983.1 - 7.6e-50 169.9 0.1 2.9e-24 86.2 0.1 2.5 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KIY44983.1 - 2e-36 126.0 22.1 1.9e-34 119.5 18.1 3.7 2 1 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KIY44983.1 - 1.1e-09 38.5 14.2 1.1e-09 38.5 14.2 3.2 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DRMBL PF07522.14 KIY44984.1 - 6.5e-27 93.9 0.0 1.2e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KIY44984.1 - 2.3e-07 30.5 0.3 1e-06 28.5 0.2 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY44984.1 - 0.00072 19.6 1.6 0.0016 18.5 1.6 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Rgp1 PF08737.10 KIY44985.1 - 4.8e-45 154.5 0.4 2.4e-43 148.9 0.4 2.9 1 1 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 KIY44985.1 - 1.6e-07 31.8 0.0 0.023 15.2 0.0 3.5 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIY44985.1 - 0.0037 17.3 0.0 0.048 13.7 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Tmemb_170 PF10190.9 KIY44986.1 - 4.2e-05 23.9 8.5 0.00022 21.5 3.4 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 TcpE PF12648.7 KIY44986.1 - 0.03 14.9 3.0 6.9 7.3 0.0 2.2 2 0 0 2 2 2 0 TcpE family TRIC PF05197.13 KIY44986.1 - 0.049 13.2 0.2 0.049 13.2 0.2 1.7 2 0 0 2 2 2 0 TRIC channel DUF2892 PF11127.8 KIY44986.1 - 6 7.0 8.7 8.2 6.5 5.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) WD40 PF00400.32 KIY44987.1 - 2.4e-53 176.9 22.7 2.3e-08 34.5 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY44987.1 - 6.7e-17 61.6 5.2 0.00053 20.2 0.0 5.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY44987.1 - 3.8e-11 43.2 0.7 1.3e-06 28.5 0.4 3.4 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIY44987.1 - 5.8e-07 28.5 7.3 0.0025 16.6 0.3 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY44987.1 - 1.5e-05 24.5 0.2 0.0033 16.8 0.0 2.9 3 1 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KIY44987.1 - 6.2e-05 22.1 5.5 1.2 8.0 0.0 4.5 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 KIY44987.1 - 0.0067 16.0 4.6 0.037 13.6 0.9 2.8 2 1 1 3 3 3 1 Cytolethal distending toxin A/C domain IKI3 PF04762.12 KIY44987.1 - 0.009 14.1 0.1 1.4 6.8 0.0 2.3 2 0 0 2 2 2 2 IKI3 family Kelch_6 PF13964.6 KIY44987.1 - 0.01 16.1 0.7 0.33 11.3 0.2 3.2 3 0 0 3 3 3 0 Kelch motif Pectate_lyase22 PF14583.6 KIY44987.1 - 0.012 14.3 0.0 0.033 12.9 0.0 1.7 1 0 0 1 1 1 0 Oligogalacturonate lyase PALB2_WD40 PF16756.5 KIY44987.1 - 0.021 13.8 4.0 1 8.2 0.3 3.4 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain RicinB_lectin_2 PF14200.6 KIY44987.1 - 0.027 15.2 2.0 1.2 9.9 1.2 3.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Utp8 PF10395.9 KIY44987.1 - 0.078 11.5 0.1 0.2 10.1 0.0 1.6 2 0 0 2 2 2 0 Utp8 family RabGAP-TBC PF00566.18 KIY44988.1 - 2.2e-43 148.4 0.0 3.8e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 KIY44988.1 - 3.1e-06 27.6 0.5 0.0004 20.8 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KIY44988.1 - 6.9e-05 22.1 0.4 0.00061 19.2 0.1 2.7 2 0 0 2 2 2 1 EF hand GRAM PF02893.20 KIY44988.1 - 7.4e-05 22.6 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 KIY44988.1 - 7.9e-05 22.3 3.0 0.00076 19.2 0.2 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KIY44988.1 - 0.00026 20.8 1.5 0.11 12.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KIY44988.1 - 0.073 13.4 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region MMR_HSR1 PF01926.23 KIY44989.1 - 2.1e-13 50.3 0.0 3.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY44989.1 - 0.0041 16.6 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIY44989.1 - 0.0059 16.7 0.0 0.3 11.1 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KIY44989.1 - 0.017 14.5 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MIP PF00230.20 KIY44990.1 - 2e-41 142.2 8.1 2.5e-41 141.9 8.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein EamA PF00892.20 KIY44990.1 - 0.043 14.0 12.0 0.061 13.5 1.2 3.2 1 1 2 3 3 3 0 EamA-like transporter family Coprogen_oxidas PF01218.18 KIY44991.1 - 9.7e-129 428.3 0.0 1.1e-128 428.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SAICAR_synt PF01259.18 KIY44992.1 - 3.9e-100 334.6 0.0 4.7e-100 334.4 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase zf-DNL PF05180.12 KIY44993.1 - 1.9e-30 104.6 1.1 2.8e-30 104.1 1.1 1.2 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.18 KIY44993.1 - 1.8 8.5 5.2 27 4.7 5.2 2.4 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) Sen15 PF09631.10 KIY44994.1 - 1.9e-19 69.8 0.1 3.1e-19 69.1 0.0 1.3 2 0 0 2 2 2 1 Sen15 protein Sds3 PF08598.11 KIY44995.1 - 7.6e-05 22.8 0.4 0.00011 22.3 0.4 1.2 1 0 0 1 1 1 1 Sds3-like DLH PF01738.18 KIY44996.1 - 8.2e-19 68.0 0.0 9.5e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Triabin PF03973.13 KIY44996.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Triabin DUF2002 PF09400.10 KIY44996.1 - 0.16 12.0 0.0 1.1 9.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2002) DUF2263 PF10021.9 KIY44997.1 - 2.1e-18 67.1 0.0 3.1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF5551 PF17705.1 KIY44997.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5551) AICARFT_IMPCHas PF01808.18 KIY44998.1 - 2.9e-89 299.4 0.1 3.6e-89 299.1 0.1 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KIY44998.1 - 9.8e-24 83.4 0.0 1.8e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain ECF-ribofla_trS PF07155.12 KIY44999.1 - 0.026 14.5 0.5 0.026 14.5 0.5 2.0 2 0 0 2 2 2 0 ECF-type riboflavin transporter, S component DUF5438 PF17506.2 KIY44999.1 - 0.16 12.3 3.7 4.4 7.7 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5438) Sugar_tr PF00083.24 KIY45000.1 - 8.3e-88 295.2 20.8 9.9e-88 295.0 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY45000.1 - 1.5e-12 47.1 46.4 2.5e-11 43.1 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BBE PF08031.12 KIY45001.1 - 0.0003 20.8 0.0 0.00044 20.3 0.0 1.2 1 0 0 1 1 1 1 Berberine and berberine like DUF2418 PF10332.9 KIY45001.1 - 0.035 14.6 0.0 0.041 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) DUF383 PF04063.14 KIY45002.1 - 3.8e-54 183.3 0.0 6.9e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KIY45002.1 - 3.7e-18 65.1 0.2 7.4e-18 64.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT PF02985.22 KIY45002.1 - 0.038 14.3 0.0 0.28 11.5 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat ECR1_N PF14382.6 KIY45002.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Adenylsucc_synt PF00709.21 KIY45003.1 - 4.2e-171 569.5 0.0 4.7e-171 569.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase AMPKBI PF04739.15 KIY45004.1 - 1.5e-23 82.8 0.0 8.5e-23 80.4 0.0 2.3 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KIY45004.1 - 2.5e-19 69.2 0.0 4.9e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Methyltransf_25 PF13649.6 KIY45005.1 - 4.3e-15 56.2 0.0 1.9e-14 54.2 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY45005.1 - 8e-15 55.1 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY45005.1 - 2.2e-13 50.7 0.2 4.5e-13 49.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY45005.1 - 2.4e-13 50.6 0.0 4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY45005.1 - 6.9e-13 48.7 0.0 1.8e-12 47.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY45005.1 - 5.1e-07 29.3 0.0 7.8e-07 28.7 0.0 1.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KIY45005.1 - 4e-05 22.9 0.0 5.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 KIY45005.1 - 5.3e-05 22.8 0.0 7.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KIY45005.1 - 0.00028 20.9 0.0 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KIY45005.1 - 0.0014 18.2 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 KIY45005.1 - 0.0014 17.6 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KIY45005.1 - 0.0048 16.3 0.0 0.0064 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KIY45005.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase tRNA_U5-meth_tr PF05958.11 KIY45005.1 - 0.05 12.6 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_29 PF03141.16 KIY45005.1 - 0.1 11.1 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 KIY45005.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) KinB_sensor PF16767.5 KIY45005.1 - 0.24 11.9 0.1 0.4 11.1 0.1 1.3 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Rtf2 PF04641.12 KIY45006.1 - 0.12 11.8 2.1 0.23 10.8 2.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Spt20 PF12090.8 KIY45007.1 - 4.8e-25 88.5 0.0 4.5e-15 55.9 0.0 8.4 2 2 3 6 6 6 2 Spt20 family DUF2977 PF11192.8 KIY45007.1 - 0.11 12.6 0.0 3.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) HD_3 PF13023.6 KIY45008.1 - 9.8e-44 149.2 0.5 1.2e-43 148.8 0.5 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KIY45008.1 - 4.8e-12 46.0 0.7 7.7e-12 45.3 0.7 1.5 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KIY45008.1 - 1.6e-05 25.1 0.5 3.5e-05 24.0 0.5 1.6 1 1 0 1 1 1 1 HD domain F-box PF00646.33 KIY45009.1 - 6.3e-05 22.7 9.2 0.00011 22.0 6.2 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY45009.1 - 0.0028 17.5 6.9 0.0082 16.0 6.9 1.9 1 0 0 1 1 1 1 F-box-like DUF4690 PF15756.5 KIY45010.1 - 0.077 13.6 0.4 0.24 12.0 0.4 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Insulin_TMD PF17870.1 KIY45010.1 - 0.13 12.4 2.6 0.24 11.5 2.6 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4083 PF13314.6 KIY45010.1 - 0.25 11.3 1.7 0.57 10.2 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) IBR PF01485.21 KIY45011.1 - 9.2e-10 38.6 34.9 4.9e-08 33.1 6.1 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain ADH_N PF08240.12 KIY45012.1 - 6.6e-28 96.8 1.6 1.2e-27 96.0 1.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY45012.1 - 5e-27 94.4 0.7 7.9e-27 93.8 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY45012.1 - 0.052 14.6 0.2 0.081 14.0 0.2 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF659 PF04937.15 KIY45013.1 - 0.00017 21.5 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Glutaredoxin PF00462.24 KIY45014.1 - 2.8e-17 62.7 0.0 5.9e-17 61.7 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin Histone PF00125.24 KIY45015.1 - 6.3e-49 165.7 3.4 7.1e-49 165.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIY45015.1 - 2.8e-05 24.4 0.1 4.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIY45015.1 - 5.3e-05 23.3 0.1 0.0001 22.3 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIY45015.1 - 0.00081 19.6 0.1 0.0015 18.8 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIY45015.1 - 0.0015 19.1 1.6 0.0019 18.8 1.6 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KIY45015.1 - 0.092 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KIY45015.1 - 0.11 12.6 0.2 0.18 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KIY45016.1 - 2.8e-07 30.6 0.1 3.4e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIY45016.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIY45016.1 - 0.00012 22.3 0.0 0.00016 22.0 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY45016.1 - 0.00091 19.5 0.1 0.0018 18.5 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY45016.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIY45016.1 - 0.056 13.5 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Nnf1 PF03980.14 KIY45017.1 - 5.9e-12 45.9 0.9 1.1e-11 45.1 0.2 1.7 1 1 1 2 2 2 1 Nnf1 APG6_N PF17675.1 KIY45017.1 - 0.0012 19.4 0.8 0.0017 18.9 0.8 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF2000 PF09391.10 KIY45017.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) Cep57_MT_bd PF06657.13 KIY45017.1 - 0.058 13.9 1.0 0.13 12.8 1.0 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 KxDL PF10241.9 KIY45017.1 - 0.094 13.0 0.0 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein zf-RING_2 PF13639.6 KIY45018.1 - 2e-08 34.4 7.0 1.1e-07 32.1 2.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIY45018.1 - 1.7e-06 28.2 8.0 7.1e-06 26.2 8.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIY45018.1 - 3.6e-06 26.7 3.4 3.6e-06 26.7 3.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY45018.1 - 4.9e-06 26.3 0.6 4.9e-06 26.3 0.6 2.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY45018.1 - 1.8e-05 24.4 4.6 0.0043 16.8 0.5 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_5 PF14634.6 KIY45018.1 - 0.00023 21.1 3.3 0.00089 19.2 3.3 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY45018.1 - 0.00049 19.9 2.0 0.00049 19.9 2.0 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY45018.1 - 0.0011 18.8 1.6 0.0011 18.8 1.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KIY45018.1 - 0.0031 17.5 0.9 0.0031 17.5 0.9 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KIY45018.1 - 0.0032 17.5 3.1 0.024 14.6 3.1 2.4 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIY45018.1 - 0.013 15.1 1.5 0.046 13.3 1.5 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 KIY45018.1 - 0.082 12.6 2.9 0.22 11.2 2.9 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-C3H2C3 PF17122.5 KIY45018.1 - 0.2 11.7 2.6 0.54 10.3 2.6 1.8 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KIY45018.1 - 3.9 7.7 9.0 0.6 10.3 3.9 2.2 2 0 0 2 2 2 0 RING-variant domain zf-RING_4 PF14570.6 KIY45018.1 - 4 7.3 6.7 0.41 10.5 1.6 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PS_Dcarbxylase PF02666.15 KIY45019.1 - 1.1e-50 172.0 0.0 1.4e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DHBP_synthase PF00926.19 KIY45020.1 - 5.3e-86 287.1 0.1 6e-86 286.9 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF247 PF03140.15 KIY45020.1 - 0.18 11.0 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function Pkinase PF00069.25 KIY45021.1 - 3.1e-69 233.3 0.0 4.1e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45021.1 - 2.7e-39 135.0 0.0 4e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY45021.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY45021.1 - 6.1e-05 22.1 0.1 8.2e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY45021.1 - 0.0012 18.8 0.1 0.03 14.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY45021.1 - 0.0026 17.2 0.1 0.0043 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family fragilysinNterm PF16376.5 KIY45021.1 - 0.17 11.6 2.3 0.43 10.3 0.1 2.3 2 1 1 3 3 3 0 N-terminal domain of fragilysin He_PIG PF05345.12 KIY45022.1 - 2.1e-11 43.8 0.3 4.1e-06 26.9 0.0 5.5 5 1 0 5 5 5 2 Putative Ig domain Dynein_light PF01221.18 KIY45023.1 - 5.6e-40 135.6 0.9 6.4e-40 135.4 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4320 PF14208.6 KIY45023.1 - 0.043 13.9 0.0 0.05 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) HEAT PF02985.22 KIY45024.1 - 1.2e-15 56.3 19.3 0.0035 17.5 0.0 10.4 11 0 0 11 11 10 3 HEAT repeat HEAT_EZ PF13513.6 KIY45024.1 - 9.3e-15 54.8 19.5 0.0013 19.2 0.0 11.4 11 2 2 13 13 12 3 HEAT-like repeat HEAT_2 PF13646.6 KIY45024.1 - 1.9e-10 41.0 10.4 0.91 10.0 0.6 8.5 7 3 3 10 10 10 6 HEAT repeats IBN_N PF03810.19 KIY45024.1 - 2.2e-08 33.9 2.3 5.3e-06 26.3 0.1 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain UME PF08064.13 KIY45024.1 - 4.4e-07 29.8 0.0 0.13 12.2 0.0 6.0 3 1 2 5 5 5 1 UME (NUC010) domain DUF3385 PF11865.8 KIY45024.1 - 8e-07 29.1 1.7 4 7.3 0.0 6.6 6 1 0 7 7 7 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 KIY45024.1 - 1.2e-06 28.4 0.2 0.094 12.4 0.1 3.7 4 1 0 4 4 4 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 KIY45024.1 - 3.4e-06 27.6 0.0 3 8.5 0.0 5.7 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KIY45024.1 - 8.6e-06 25.9 0.0 2.8 8.0 0.0 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 KIY45024.1 - 0.0032 15.8 0.0 5.5 5.2 0.0 4.2 4 2 1 5 5 5 1 Down-regulated in metastasis CLASP_N PF12348.8 KIY45024.1 - 0.0052 16.4 0.1 6.2 6.3 0.0 4.4 5 0 0 5 5 5 1 CLASP N terminal Xpo1 PF08389.12 KIY45024.1 - 0.027 14.5 0.2 1.6 8.8 0.0 3.7 2 1 1 3 3 3 0 Exportin 1-like protein Adaptin_N PF01602.20 KIY45024.1 - 0.031 12.8 5.3 0.57 8.7 0.1 4.3 5 0 0 5 5 5 0 Adaptin N terminal region Gag_p24 PF00607.20 KIY45024.1 - 0.15 11.9 0.0 0.45 10.3 0.0 1.8 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) SEFIR PF08357.11 KIY45025.1 - 0.14 12.4 0.0 0.43 10.9 0.0 1.8 1 1 0 1 1 1 0 SEFIR domain Nup192 PF11894.8 KIY45026.1 - 6.6e-210 699.9 0.0 8.5e-210 699.5 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 CLU PF13236.6 KIY45027.1 - 0.21 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Clustered mitochondria HAUS4 PF14735.6 KIY45028.1 - 0.016 14.9 0.4 0.029 14.1 0.0 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 PglD_N PF17836.1 KIY45028.1 - 0.17 12.5 0.0 1.1 9.9 0.0 2.0 2 0 0 2 2 2 0 PglD N-terminal domain CN_hydrolase PF00795.22 KIY45029.1 - 1.1e-40 139.6 0.0 1.7e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KIY45029.1 - 1.8e-23 83.0 0.0 4.3e-23 81.7 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KIY45029.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Sec6 PF06046.13 KIY45031.1 - 7.4e-150 500.1 5.6 1.7e-149 498.9 2.4 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KIY45031.1 - 0.00017 20.7 3.1 0.02 13.8 0.7 2.7 2 0 0 2 2 2 2 Vps53-like, N-terminal Vps5 PF09325.10 KIY45031.1 - 0.014 14.9 0.4 0.044 13.3 0.4 1.8 1 0 0 1 1 1 0 Vps5 C terminal like HECT PF00632.25 KIY45031.1 - 0.095 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Adeno_VII PF03228.14 KIY45031.1 - 0.17 12.5 0.5 8.5 7.0 0.1 3.0 3 0 0 3 3 3 0 Adenoviral core protein VII COG2 PF06148.11 KIY45031.1 - 0.74 9.9 9.7 11 6.1 0.1 5.1 4 1 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3829 PF12889.7 KIY45031.1 - 1.4 8.3 5.6 0.33 10.4 0.3 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3829) FAD_binding_3 PF01494.19 KIY45032.1 - 9.3e-23 81.0 0.1 6.7e-13 48.6 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIY45032.1 - 3.2e-06 26.4 0.1 0.00011 21.4 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY45032.1 - 0.0001 21.7 0.0 0.00048 19.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY45032.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY45032.1 - 0.00015 20.8 0.6 0.0044 15.9 0.1 2.9 4 0 0 4 4 4 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KIY45032.1 - 0.0016 18.4 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 KIY45032.1 - 0.0057 15.9 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 KIY45032.1 - 0.0086 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 KIY45032.1 - 0.014 15.6 0.3 0.033 14.4 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY45032.1 - 0.055 12.5 0.9 0.099 11.7 0.9 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KIY45032.1 - 0.081 12.2 2.2 0.21 10.8 1.8 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_61 PF03443.14 KIY45033.1 - 2.3e-25 89.7 0.0 3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Bromo_TP PF07524.13 KIY45035.1 - 0.032 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Nop14 PF04147.12 KIY45036.1 - 0.036 12.3 14.8 0.049 11.9 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family Tub_N PF16322.5 KIY45036.1 - 1.2 9.4 12.5 2 8.8 12.5 1.3 1 0 0 1 1 1 0 Tubby N-terminal CCDC53 PF10152.9 KIY45037.1 - 0.075 13.5 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Cyt-b5 PF00173.28 KIY45038.1 - 8.7e-17 61.0 0.1 2e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KIY45038.1 - 3.8e-10 40.2 13.9 3.8e-10 40.2 13.9 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 KIY45039.1 - 6.7e-16 58.2 0.1 1.3e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KIY45039.1 - 5.7e-12 46.1 15.7 5.7e-12 46.1 15.7 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HupF_HypC PF01455.18 KIY45039.1 - 0.065 13.4 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 HupF/HypC family Mg_trans_NIPA PF05653.14 KIY45040.1 - 1.3e-97 326.5 9.9 1.5e-97 326.3 9.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KIY45040.1 - 0.0047 17.1 3.6 0.0047 17.1 3.6 4.0 3 1 0 3 3 3 1 EamA-like transporter family HXXEE PF13787.6 KIY45040.1 - 7.9 7.3 8.3 17 6.3 0.1 3.3 2 1 2 4 4 4 0 Protein of unknown function with HXXEE motif Iso_dh PF00180.20 KIY45041.1 - 2.6e-77 260.3 0.0 3.1e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DHFR_2 PF06442.11 KIY45041.1 - 0.12 12.2 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 R67 dihydrofolate reductase BolA PF01722.18 KIY45042.1 - 3.8e-17 62.3 0.2 1e-16 61.0 0.2 1.5 1 1 0 1 1 1 1 BolA-like protein Ribosomal_L44 PF00935.19 KIY45043.1 - 5.5e-37 126.1 12.8 5.5e-37 126.1 12.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L44 Cathelicidins PF00666.17 KIY45043.1 - 0.84 10.0 5.5 0.11 12.9 1.3 1.6 2 0 0 2 2 2 0 Cathelicidin CTP_synth_N PF06418.14 KIY45044.1 - 4.8e-121 403.1 0.4 6.5e-121 402.7 0.4 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KIY45044.1 - 1.3e-51 175.1 0.0 2.2e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIY45044.1 - 0.0094 15.7 0.1 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 KIY45044.1 - 0.056 13.5 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIY45044.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase Sulf_transp PF04143.14 KIY45045.1 - 3.4e-05 23.6 9.5 3.4e-05 23.6 9.5 2.9 1 1 2 3 3 3 1 Sulphur transport NAD_binding_4 PF07993.12 KIY45047.1 - 1.8e-64 217.4 0.0 2.9e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIY45047.1 - 6e-64 216.2 0.3 3.3e-63 213.7 0.3 1.9 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KIY45047.1 - 1.4e-12 47.8 0.0 7.2e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 KIY45047.1 - 3.7e-12 45.7 0.0 1.9e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.19 KIY45047.1 - 3e-06 26.4 0.1 9.5e-06 24.8 0.0 1.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIY45047.1 - 1.8e-05 24.3 0.0 4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KIY45047.1 - 0.00022 22.1 0.0 0.0013 19.6 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CBM_21 PF03370.13 KIY45048.1 - 1.4e-26 92.9 0.0 1.6e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIY45048.1 - 3.2e-10 40.5 0.1 4e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Arrestin_C PF02752.22 KIY45049.1 - 6.1e-08 33.2 0.1 2.5e-07 31.2 0.1 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIY45049.1 - 7.6e-06 26.0 0.0 3.7e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KIY45049.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like DUF3958 PF13125.6 KIY45050.1 - 0.62 10.3 8.4 2 8.7 8.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) HAUS6_N PF14661.6 KIY45050.1 - 0.97 9.0 5.8 1.5 8.4 5.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.13 KIY45050.1 - 2.5 7.3 4.4 3.4 6.8 4.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4404 PF14357.6 KIY45050.1 - 6.9 7.4 8.3 19 5.9 0.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) DUF2046 PF09755.9 KIY45051.1 - 1.2e-17 64.1 21.8 6.5e-11 42.0 7.6 2.3 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) FlaC_arch PF05377.11 KIY45051.1 - 0.088 13.2 2.1 0.36 11.3 0.1 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ChAPs PF09295.10 KIY45052.1 - 6.7e-139 463.3 0.0 1.1e-137 459.3 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KIY45052.1 - 6.2e-06 26.6 0.8 0.035 14.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY45052.1 - 7.8e-06 25.6 0.5 5.9 7.3 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY45052.1 - 2.7e-05 24.0 0.1 4 7.9 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY45052.1 - 0.0074 17.0 2.4 4.9 8.2 0.0 4.8 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIY45052.1 - 0.032 13.4 5.0 2.2 7.4 0.8 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY45052.1 - 0.034 14.4 6.2 0.16 12.2 1.3 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KIY45052.1 - 0.054 12.4 0.2 0.29 10.0 0.0 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KIY45052.1 - 0.08 13.6 3.7 85 4.1 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIY45052.1 - 5 6.4 6.8 1.7 7.9 0.2 2.6 3 0 0 3 3 3 0 MalT-like TPR region AA_kinase PF00696.28 KIY45054.1 - 1.5e-36 126.2 0.0 4.9e-36 124.5 0.0 1.8 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KIY45054.1 - 8.9e-12 44.6 1.4 3.5e-06 26.7 0.0 3.5 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 KIY45054.1 - 1.1e-10 41.2 1.3 4.7e-08 32.7 0.1 3.2 3 0 0 3 3 3 2 ACT domain DEAD PF00270.29 KIY45055.1 - 6.9e-36 123.6 0.3 2.9e-35 121.6 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY45055.1 - 1.7e-18 67.0 0.2 1.2e-17 64.2 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain bZIP_1 PF00170.21 KIY45056.1 - 1.4e-06 28.3 4.4 2.3e-06 27.6 3.5 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KIY45056.1 - 0.00013 22.0 7.8 0.0014 18.7 4.0 2.3 1 1 1 2 2 2 2 Basic region leucine zipper FAM104 PF15434.6 KIY45056.1 - 0.42 11.2 4.0 0.84 10.2 0.4 2.8 2 0 0 2 2 2 0 Family 104 NARP1 PF12569.8 KIY45057.1 - 7.5e-141 470.6 9.5 6.2e-139 464.2 1.8 3.1 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 KIY45057.1 - 1.5e-10 40.9 13.9 0.00086 19.9 0.2 9.3 7 2 4 11 11 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY45057.1 - 5.4e-10 39.6 20.5 0.034 14.6 2.2 7.8 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY45057.1 - 5.6e-08 33.3 11.9 0.071 13.8 0.5 7.2 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY45057.1 - 4.6e-07 29.5 0.6 0.0014 18.5 0.1 8.5 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY45057.1 - 6.8e-07 28.8 14.8 0.015 15.1 0.5 6.7 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY45057.1 - 1.3e-06 28.4 6.1 0.27 11.4 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY45057.1 - 1.5e-06 28.2 2.9 1.1 9.8 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY45057.1 - 5.9e-06 25.9 12.1 0.00023 20.8 1.5 5.1 5 1 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 KIY45057.1 - 9e-06 25.4 4.5 0.23 11.6 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY45057.1 - 0.00016 21.6 15.7 0.0092 16.1 0.1 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY45057.1 - 0.0018 18.4 8.5 1.2 9.4 0.2 5.2 4 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KIY45057.1 - 0.0065 16.7 16.8 0.7 10.2 0.6 6.0 5 2 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY45057.1 - 0.01 16.4 8.4 13 6.6 0.0 6.7 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIY45057.1 - 0.078 12.3 2.1 5.2 6.3 0.5 4.0 2 1 1 3 3 3 0 MalT-like TPR region Phage_term_smal PF05944.12 KIY45057.1 - 0.089 12.8 0.2 11 6.0 0.0 3.1 3 0 0 3 3 3 0 Phage small terminase subunit DUF523 PF04463.12 KIY45057.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF523) Fis1_TPR_C PF14853.6 KIY45057.1 - 0.14 12.3 7.3 1.5 9.0 0.1 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KIY45057.1 - 8.2 6.4 8.6 36 4.4 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Metallophos PF00149.28 KIY45058.1 - 2.7e-36 126.0 0.1 3.5e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KIY45058.1 - 0.00012 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain HEAT_2 PF13646.6 KIY45059.1 - 9.8e-05 22.7 7.5 0.026 14.9 0.0 5.8 3 2 1 5 5 5 1 HEAT repeats HEAT PF02985.22 KIY45059.1 - 0.0003 20.8 6.5 7.1 7.2 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KIY45059.1 - 0.0046 17.4 4.9 0.99 10.0 0.2 4.5 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 KIY45059.1 - 0.021 14.9 5.6 1.7 8.6 0.0 4.2 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 p450 PF00067.22 KIY45060.1 - 8.3e-66 222.6 0.0 1e-65 222.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cyclin_N PF00134.23 KIY45061.1 - 5.1e-12 45.7 0.3 1.6e-10 40.8 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KIY45061.1 - 0.0036 17.7 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 KIY45061.1 - 0.014 15.5 0.4 2.1 8.4 0.1 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.19 KIY45061.1 - 0.046 13.8 0.4 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat NUC153 PF08159.12 KIY45062.1 - 6.1e-12 45.1 0.3 1.1e-11 44.3 0.3 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KIY45062.1 - 0.0013 19.5 0.1 5.6 8.0 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat CDC45 PF02724.14 KIY45062.1 - 0.072 11.4 7.0 0.17 10.1 7.0 1.6 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_4 PF13894.6 KIY45063.1 - 1.9e-05 25.1 3.0 0.063 14.1 0.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY45063.1 - 0.0028 18.0 8.4 0.017 15.6 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KIY45063.1 - 0.0048 17.2 0.0 0.022 15.1 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY45063.1 - 0.046 14.0 1.0 0.21 11.9 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIY45063.1 - 0.37 11.1 3.2 1.2 9.5 3.1 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Gti1_Pac2 PF09729.9 KIY45064.1 - 3.6e-25 89.1 0.2 2.1e-22 80.1 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family HhH-GPD PF00730.25 KIY45065.1 - 4.6e-19 68.9 0.0 1.3e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KIY45065.1 - 1.2e-09 38.1 0.0 3.8e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 KIY45065.1 - 0.00063 19.5 0.1 0.0022 17.8 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KIY45065.1 - 0.082 13.3 5.5 0.25 11.7 5.5 1.9 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Apo-VLDL-II PF05418.11 KIY45065.1 - 0.18 12.4 0.3 0.35 11.5 0.3 1.4 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) HMG-CoA_red PF00368.18 KIY45066.1 - 4.4e-140 466.9 5.8 5.9e-140 466.5 5.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KIY45066.1 - 2.7e-11 43.6 4.4 3.6e-10 39.9 4.4 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KIY45066.1 - 0.00042 18.6 0.2 0.00068 17.9 0.2 1.2 1 0 0 1 1 1 1 Patched family Acetyltransf_1 PF00583.25 KIY45067.1 - 1.3e-06 28.6 0.0 2.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KIY45067.1 - 6.7e-05 23.6 0.0 0.00012 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY45067.1 - 0.042 14.3 0.0 0.075 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SURF4 PF02077.15 KIY45068.1 - 2.6e-94 315.8 6.2 3.1e-94 315.5 6.2 1.0 1 0 0 1 1 1 1 SURF4 family NMN_transporter PF04973.12 KIY45068.1 - 0.13 12.2 10.8 0.17 11.8 10.2 1.6 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter DUF1664 PF07889.12 KIY45069.1 - 0.13 12.3 12.7 0.28 11.2 1.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KIY45069.1 - 0.36 11.4 32.9 2.1 8.9 11.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF5082 PF16888.5 KIY45069.1 - 0.87 9.9 12.3 9.6 6.5 11.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DNA_topoisoIV PF00521.20 KIY45069.1 - 2.6 6.9 14.5 3.3 6.5 14.5 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A PI3K_P85_iSH2 PF16454.5 KIY45069.1 - 3.3 7.3 20.7 0.94 9.1 3.0 2.7 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ATG16 PF08614.11 KIY45069.1 - 3.4 7.8 32.3 0.68 10.1 10.2 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KIY45069.1 - 5.2 7.1 32.3 1.1 9.2 9.3 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KIY45069.1 - 5.2 5.8 28.6 0.57 9.0 4.6 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein FlxA PF14282.6 KIY45069.1 - 9.6 6.3 16.9 0.92 9.5 1.9 2.9 1 1 2 3 3 3 0 FlxA-like protein HIP1_clath_bdg PF16515.5 KIY45069.1 - 9.8 6.9 27.5 0.6 10.7 9.9 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FUSC PF04632.12 KIY45069.1 - 9.9 4.6 14.0 13 4.2 14.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GATA PF00320.27 KIY45070.1 - 7.4e-23 79.9 15.0 4.3e-13 48.6 4.4 2.2 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KIY45070.1 - 0.00024 20.5 3.0 0.28 10.7 0.3 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KIY45070.1 - 0.0039 17.3 5.0 0.39 10.9 0.2 2.5 2 1 0 2 2 2 2 Zinc ribbon domain DUF2387 PF09526.10 KIY45070.1 - 0.0046 17.1 2.6 0.057 13.6 0.2 2.1 1 1 1 2 2 2 1 Probable metal-binding protein (DUF2387) zf-RRPl_C4 PF17026.5 KIY45070.1 - 0.01 15.9 2.9 0.078 13.1 1.2 2.2 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type eIF-5_eIF-2B PF01873.17 KIY45070.1 - 0.011 15.6 5.3 0.079 12.8 0.4 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 KIY45070.1 - 0.021 14.8 1.1 0.021 14.8 1.1 2.3 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 KIY45070.1 - 0.037 14.0 9.4 7.6 6.7 2.4 2.9 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KIY45070.1 - 0.054 13.5 2.8 0.054 13.5 2.8 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Vps36-NZF-N PF16988.5 KIY45070.1 - 0.077 12.4 4.6 2.5 7.6 0.6 2.7 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RRN7 PF11781.8 KIY45070.1 - 0.12 12.1 6.6 0.32 10.7 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C4pol PF14260.6 KIY45070.1 - 0.23 12.0 5.3 11 6.6 0.1 2.8 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Elf1 PF05129.13 KIY45070.1 - 0.29 11.2 5.1 0.77 9.8 0.2 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-UBP PF02148.19 KIY45070.1 - 0.44 10.9 5.3 8.5 6.8 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Tnp_zf-ribbon_2 PF13842.6 KIY45070.1 - 4.6 8.1 13.9 5.7 7.8 3.1 3.4 3 1 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon Prim_Zn_Ribbon PF08273.12 KIY45070.1 - 5.1 7.5 10.2 14 6.0 0.3 3.6 3 1 1 4 4 4 0 Zinc-binding domain of primase-helicase zf-ZPR1 PF03367.13 KIY45072.1 - 5.1e-112 370.9 0.0 5.4e-57 192.1 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DZR PF12773.7 KIY45072.1 - 0.097 12.7 2.0 7.8 6.6 0.1 3.1 3 0 0 3 3 3 0 Double zinc ribbon Cytochrome_C7 PF14522.6 KIY45072.1 - 0.14 12.2 1.0 0.96 9.5 0.1 2.4 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Zn-ribbon_8 PF09723.10 KIY45072.1 - 0.23 11.6 3.8 36 4.6 0.0 3.6 3 1 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KIY45072.1 - 2.6 7.6 7.2 12 5.5 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KIY45072.1 - 5.3 6.8 10.0 1.8 8.3 0.7 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain Ion_trans_2 PF07885.16 KIY45073.1 - 1.1e-25 89.4 38.9 1.5e-13 50.5 16.6 3.0 3 0 0 3 3 3 2 Ion channel DUF2754 PF10953.8 KIY45073.1 - 0.29 11.4 3.6 0.99 9.7 3.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) DUF3989 PF13150.6 KIY45073.1 - 4.4 7.1 4.9 30 4.4 1.3 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3989) DUF3325 PF11804.8 KIY45073.1 - 5.9 7.1 7.2 8.1 6.7 1.6 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF3325) Fe-ADH PF00465.19 KIY45074.1 - 1.7e-56 191.7 4.0 2.1e-56 191.3 4.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIY45074.1 - 3e-31 109.0 1.6 3.8e-31 108.7 1.6 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 KIY45074.1 - 1.7e-07 30.7 2.4 2.4e-06 26.9 2.4 2.1 1 1 0 1 1 1 1 3-dehydroquinate synthase DER1 PF04511.15 KIY45076.1 - 2.5e-30 105.8 1.6 3.2e-30 105.5 1.6 1.0 1 0 0 1 1 1 1 Der1-like family JTB PF05439.12 KIY45077.1 - 1.3e-06 28.4 0.1 1.3e-06 28.4 0.1 1.5 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) DUF21 PF01595.20 KIY45077.1 - 0.12 12.0 0.1 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF1003 PF06210.11 KIY45077.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) SHMT PF00464.19 KIY45078.1 - 2.8e-167 556.4 0.0 3.4e-167 556.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KIY45078.1 - 0.066 12.5 0.0 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase CDC45 PF02724.14 KIY45079.1 - 0.13 10.6 7.3 0.16 10.3 7.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KIY45079.1 - 3.1 5.9 10.1 4 5.5 10.1 1.2 1 0 0 1 1 1 0 Nop14-like family SRP19 PF01922.17 KIY45080.1 - 1.3e-27 96.5 0.0 2.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein PCSK9_C1 PF18459.1 KIY45081.1 - 0.037 14.2 1.8 0.097 12.8 1.8 1.7 1 1 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PALP PF00291.25 KIY45082.1 - 4.5e-31 108.4 0.2 5.5e-31 108.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF212 PF02681.14 KIY45082.1 - 0.024 14.8 0.2 0.073 13.2 0.0 1.8 2 0 0 2 2 2 0 Divergent PAP2 family COesterase PF00135.28 KIY45083.1 - 1.3e-36 126.6 0.0 4.8e-36 124.7 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY45083.1 - 0.00018 21.5 1.5 0.00048 20.0 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF202 PF02656.15 KIY45085.1 - 3e-17 62.8 2.9 3e-17 62.8 2.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Abhydrolase_9_N PF15420.6 KIY45085.1 - 0.015 15.3 6.6 0.017 15.2 6.6 1.0 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus S_4TM PF18159.1 KIY45085.1 - 0.65 9.2 8.5 0.22 10.8 5.4 1.8 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain zf-ANAPC11 PF12861.7 KIY45086.1 - 3.9e-41 139.0 11.7 4.4e-41 138.8 11.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY45086.1 - 1.6e-21 76.3 11.6 2.4e-21 75.7 11.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIY45086.1 - 0.001 19.4 19.3 0.0032 17.7 15.8 2.5 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY45086.1 - 0.075 13.1 10.4 0.22 11.6 10.4 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY45086.1 - 0.081 12.8 13.4 0.43 10.5 13.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY45086.1 - 0.27 11.2 14.4 4.5 7.3 15.0 2.6 1 1 1 2 2 2 0 zinc-RING finger domain RINGv PF12906.7 KIY45086.1 - 1.1 9.4 11.3 0.14 12.3 4.5 2.4 2 1 0 2 2 2 0 RING-variant domain zf-C3HC4_2 PF13923.6 KIY45086.1 - 5.4 7.0 18.9 0.99 9.3 12.0 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Alpha-L-AF_C PF06964.12 KIY45087.1 - 2.6e-38 131.8 0.6 4.5e-38 131.0 0.1 1.6 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KIY45087.1 - 0.0029 17.9 0.6 0.011 16.0 0.6 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain TAL_FSA PF00923.19 KIY45088.1 - 1.5e-47 162.4 1.1 1.8e-47 162.1 1.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase mTERF PF02536.14 KIY45088.1 - 0.012 14.6 0.2 0.025 13.5 0.0 1.6 2 0 0 2 2 2 0 mTERF K-cyclin_vir_C PF09080.10 KIY45088.1 - 0.083 13.3 2.0 0.16 12.4 0.5 2.3 2 0 0 2 2 2 0 K cyclin, C terminal CRIM PF16978.5 KIY45089.1 - 1.6e-39 135.3 0.0 2.7e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KIY45089.1 - 1.3e-31 109.1 0.0 2.1e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 KIY45089.1 - 0.00067 19.7 0.0 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 KIY45089.1 - 0.00071 19.8 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain PH PF00169.29 KIY45089.1 - 0.043 14.3 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 PH domain RA PF00788.23 KIY45089.1 - 0.05 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Antimicrobial_8 PF08103.11 KIY45089.1 - 0.067 13.4 2.0 5.1 7.4 0.0 3.2 3 0 0 3 3 3 0 Uperin family SPX PF03105.19 KIY45090.1 - 2.2e-30 106.9 0.0 6.7e-29 102.0 0.0 2.1 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.25 KIY45090.1 - 3.2e-08 33.3 7.9 7e-08 32.2 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY45090.1 - 3e-07 30.2 7.8 3e-07 30.2 7.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY45090.1 - 6.6e-07 29.4 7.6 1.3e-06 28.4 7.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIY45090.1 - 1.7e-06 28.2 8.4 4.2e-06 27.0 8.4 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIY45090.1 - 1.9e-06 27.6 7.5 4.1e-06 26.6 7.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIY45090.1 - 1.3e-05 25.0 7.0 3.2e-05 23.8 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY45090.1 - 6.7e-05 22.8 5.6 0.00013 21.9 5.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KIY45090.1 - 0.00033 20.4 2.1 0.00078 19.2 2.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KIY45090.1 - 0.00035 20.3 8.8 0.00068 19.4 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY45090.1 - 0.0048 17.2 4.9 0.013 15.7 4.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KIY45090.1 - 0.034 14.3 5.5 0.073 13.2 5.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KIY45090.1 - 0.063 13.2 4.0 0.13 12.2 4.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KIY45090.1 - 0.071 13.2 2.7 0.22 11.6 2.7 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4336 PF14234.6 KIY45091.1 - 8.9e-13 48.1 0.0 0.0018 17.5 0.0 3.0 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) Cyclin PF08613.11 KIY45092.1 - 4e-11 43.5 0.0 4.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KIY45092.1 - 1.4e-10 41.0 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cellulase PF00150.18 KIY45093.1 - 2.4e-32 112.5 1.8 3.8e-32 111.8 1.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.13 KIY45094.1 - 1.9e-17 63.9 0.1 2.4e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY45094.1 - 1e-14 54.2 0.0 1.4e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KIY45094.1 - 0.021 14.6 0.1 0.26 11.1 0.0 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KIY45094.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) MIF4G PF02854.19 KIY45095.1 - 4.2e-38 131.1 0.1 2.1e-37 128.8 0.1 2.0 1 1 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KIY45095.1 - 2e-18 66.3 0.0 4.6e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 KIY45095.1 - 1.1e-07 31.8 0.3 5.2e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 MA3 domain Spidroin_N PF16763.5 KIY45095.1 - 0.031 14.3 0.4 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term HNF-1_N PF04814.13 KIY45095.1 - 0.057 14.0 8.3 0.83 10.2 1.5 2.4 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus HEAT PF02985.22 KIY45096.1 - 0.037 14.3 0.0 0.16 12.3 0.0 2.2 1 0 0 1 1 1 0 HEAT repeat HEAT_2 PF13646.6 KIY45096.1 - 0.04 14.3 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats PQ-loop PF04193.14 KIY45097.1 - 1e-27 95.6 1.3 1.2e-12 47.4 0.3 2.5 2 0 0 2 2 2 2 PQ loop repeat MatE PF01554.18 KIY45098.1 - 5.3e-48 162.7 22.0 6.9e-26 90.8 7.4 2.8 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 KIY45098.1 - 3.7e-07 30.3 8.6 3.7e-07 30.3 8.6 4.2 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain CnrY PF17524.2 KIY45098.1 - 0.074 13.3 0.7 0.23 11.7 0.7 1.9 1 0 0 1 1 1 0 Anti-sigma factor CnrY Glyco_hydro_18 PF00704.28 KIY45099.1 - 8.6e-62 209.6 3.4 1e-61 209.4 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FA_desaturase PF00487.24 KIY45100.1 - 1.1e-23 84.3 21.4 2.1e-23 83.4 19.4 1.9 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 KIY45100.1 - 2.9e-18 65.0 0.5 6.5e-18 63.9 0.5 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Pkinase PF00069.25 KIY45101.1 - 1.4e-49 168.9 0.0 1.9e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45101.1 - 5.9e-49 166.7 0.0 7.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY45101.1 - 0.0043 17.0 0.0 0.007 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY45101.1 - 0.0056 16.0 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY45101.1 - 0.051 12.5 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KIY45101.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KIY45101.1 - 0.27 10.0 0.0 0.39 9.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase zf-MYND PF01753.18 KIY45102.1 - 3.1e-08 33.6 15.4 6.9e-08 32.4 15.4 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY45102.1 - 0.11 12.8 11.3 0.26 11.6 11.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-ribbon_3 PF13248.6 KIY45102.1 - 0.21 11.0 2.1 0.5 9.8 2.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Bin3 PF06859.12 KIY45103.1 - 1.8e-35 121.8 0.0 2.4e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 KIY45103.1 - 8.5e-13 48.8 0.0 2.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KIY45103.1 - 3.6e-12 46.4 0.0 4.9e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY45103.1 - 1.1e-11 45.2 0.1 0.00011 22.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KIY45103.1 - 9.4e-11 41.7 0.0 0.00015 21.6 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KIY45103.1 - 7.2e-09 36.3 0.0 0.00055 20.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 KIY45103.1 - 0.00017 21.1 0.0 0.0081 15.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KIY45103.1 - 0.0014 18.2 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 KIY45103.1 - 0.0016 17.8 0.1 0.23 10.7 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 KIY45103.1 - 0.0054 16.3 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.11 KIY45103.1 - 0.026 13.5 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 KIY45103.1 - 0.09 13.8 0.0 0.23 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KIY45103.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KIY45103.1 - 0.26 11.2 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 KIY45104.1 - 2.6e-06 27.2 0.3 9.1e-06 25.5 0.3 2.1 1 1 0 1 1 1 1 F-box-like Snurportin1 PF11538.8 KIY45105.1 - 2.3e-05 24.5 1.7 2.3e-05 24.5 1.7 2.2 2 0 0 2 2 2 1 Snurportin1 Baculo_PP31 PF05311.11 KIY45105.1 - 0.53 9.7 3.4 0.37 10.2 0.1 1.9 1 1 1 2 2 2 0 Baculovirus 33KDa late protein (PP31) UCH PF00443.29 KIY45106.1 - 5.1e-37 127.8 0.0 2.9e-36 125.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY45106.1 - 4.4e-09 36.4 0.1 0.007 16.0 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase ADH_N PF08240.12 KIY45107.1 - 9.1e-35 118.8 1.4 1.6e-34 118.0 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY45107.1 - 3.7e-16 59.3 0.0 6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY45107.1 - 3.2e-10 39.8 0.0 4.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIY45107.1 - 2.6e-06 28.5 0.0 4.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KIY45107.1 - 0.001 18.4 0.8 0.0014 17.9 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Staph_opine_DH PF10100.9 KIY45107.1 - 0.0064 15.2 0.0 0.0089 14.7 0.0 1.2 1 0 0 1 1 1 1 Staphylopine dehydrogenase NAD_binding_7 PF13241.6 KIY45107.1 - 0.099 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KIY45107.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PBP PF01161.20 KIY45108.1 - 4.4e-16 59.4 0.1 9e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PspA_IM30 PF04012.12 KIY45108.1 - 0.031 13.9 0.4 0.043 13.4 0.4 1.2 1 0 0 1 1 1 0 PspA/IM30 family Pmp3 PF01679.17 KIY45109.1 - 7.3e-25 86.9 12.1 8.9e-25 86.6 12.1 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.8 KIY45109.1 - 0.022 14.8 0.3 0.032 14.3 0.3 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal G-alpha PF00503.20 KIY45110.1 - 2.5e-104 349.2 0.0 3e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY45110.1 - 3e-13 49.6 0.1 1.6e-08 34.2 0.0 2.8 3 1 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 KIY45110.1 - 0.0011 19.2 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIY45110.1 - 0.0051 16.2 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 KIY45110.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KIY45110.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KIY45110.1 - 0.12 11.7 0.0 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Abhydrolase_4 PF08386.10 KIY45111.1 - 1e-19 70.5 0.0 2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KIY45111.1 - 1.6e-12 47.6 0.3 1.2e-09 38.2 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold GRA6 PF05084.13 KIY45111.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) GST_N_3 PF13417.6 KIY45112.1 - 6.4e-11 42.5 0.0 2.2e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY45112.1 - 2e-08 34.4 0.0 4.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY45112.1 - 0.00056 19.9 0.1 0.00088 19.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY45112.1 - 0.025 14.8 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY45112.1 - 0.059 13.6 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.27 KIY45113.1 - 2.5e-55 184.4 3.0 4.3e-20 71.4 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Cons_hypoth95 PF03602.15 KIY45113.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Hira PF07569.11 KIY45114.1 - 5.3e-46 157.1 0.1 1.4e-45 155.7 0.0 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 KIY45114.1 - 1.1e-27 95.7 14.9 4.8e-06 27.2 0.1 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY45114.1 - 1.5e-12 47.6 0.4 0.72 10.2 0.0 6.7 5 1 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain AT_hook PF02178.19 KIY45116.1 - 0.019 14.8 12.4 0.38 10.8 1.3 2.8 2 0 0 2 2 2 0 AT hook motif Hydin_ADK PF17213.3 KIY45116.1 - 0.061 13.6 0.6 0.2 11.9 0.6 1.8 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain HMG_box PF00505.19 KIY45116.1 - 0.076 13.4 0.4 0.2 12.1 0.4 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box HAUS6_N PF14661.6 KIY45116.1 - 0.097 12.2 0.1 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HMG_box_2 PF09011.10 KIY45116.1 - 0.16 12.6 0.5 0.4 11.3 0.5 1.6 1 0 0 1 1 1 0 HMG-box domain ATPase_gene1 PF09527.10 KIY45117.1 - 0.14 12.3 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Retrotran_gag_2 PF14223.6 KIY45118.1 - 1.4e-12 47.4 0.2 2.8e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIY45118.1 - 0.0004 20.1 0.0 0.099 12.5 0.0 2.9 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIY45118.1 - 0.044 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) CxC2 PF18803.1 KIY45119.1 - 1.8e-29 102.1 0.1 3.3e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY45119.1 - 6.6e-05 22.7 0.7 0.00021 21.1 0.0 2.0 2 1 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY45119.1 - 0.00071 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases RVT_2 PF07727.14 KIY45121.1 - 0.078 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3239 PF11580.8 KIY45122.1 - 0.18 12.1 0.0 0.35 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3239) RVT_1 PF00078.27 KIY45123.1 - 1.9e-06 27.5 0.1 5.7e-06 26.0 0.0 1.8 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 KIY45124.1 - 0.017 14.6 0.0 0.039 13.5 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family ICA69 PF04629.14 KIY45124.1 - 0.36 11.1 4.6 0.68 10.2 4.6 1.4 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain FlxA PF14282.6 KIY45124.1 - 0.79 9.8 4.7 0.26 11.3 0.9 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF4404 PF14357.6 KIY45124.1 - 1.9 9.2 5.2 6.6 7.4 1.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Ribosomal_L2_C PF03947.18 KIY45126.1 - 3.6e-45 153.2 2.5 5.6e-45 152.6 2.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KIY45126.1 - 8.5e-15 54.5 0.0 2.1e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain JmjC PF02373.22 KIY45127.1 - 4.2e-13 49.7 0.0 1.4e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KIY45127.1 - 0.037 13.7 0.0 0.083 12.6 0.0 1.7 1 1 0 1 1 1 0 Cupin-like domain FYVE PF01363.21 KIY45127.1 - 7.3 6.8 16.8 0.07 13.3 6.0 2.7 3 0 0 3 3 3 0 FYVE zinc finger Nop PF01798.18 KIY45128.1 - 9.5e-87 290.3 0.3 9.5e-87 290.3 0.3 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KIY45128.1 - 9e-19 67.6 0.1 2.7e-18 66.1 0.1 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain JIP_LZII PF16471.5 KIY45128.1 - 0.021 15.0 0.3 0.078 13.2 0.3 2.0 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II CCDC53 PF10152.9 KIY45128.1 - 0.42 11.0 5.9 0.86 10.0 5.9 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RNA_polI_A34 PF08208.11 KIY45128.1 - 0.67 10.0 19.1 1.1 9.3 19.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 KIY45128.1 - 4 7.2 16.9 71 3.2 15.4 2.4 2 0 0 2 2 2 0 Coilin N-terminus SH3_1 PF00018.28 KIY45131.1 - 1.8e-14 53.0 0.0 2.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY45131.1 - 9.6e-13 47.8 0.2 2e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KIY45131.1 - 3.3e-12 45.9 0.0 4.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ATP_bind_3 PF01171.20 KIY45132.1 - 1.1e-16 61.1 0.0 1.8e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KIY45132.1 - 1.2e-15 56.7 2.1 1.2e-15 56.7 2.1 3.8 4 0 0 4 4 4 1 Zinc-ribbon Whib PF02467.16 KIY45132.1 - 0.044 14.4 0.4 0.044 14.4 0.4 2.1 3 0 0 3 3 3 0 Transcription factor WhiB tRNA_Me_trans PF03054.16 KIY45132.1 - 0.077 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF2616 PF11077.8 KIY45132.1 - 2.3 7.9 6.5 3.4 7.4 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) CTU2 PF10288.9 KIY45132.1 - 2.6 8.3 7.0 0.43 10.9 0.3 2.7 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 TF_Zn_Ribbon PF08271.12 KIY45132.1 - 5.2 6.7 13.5 2.2 7.9 0.2 3.9 3 1 1 4 4 4 0 TFIIB zinc-binding LRR_6 PF13516.6 KIY45136.1 - 0.035 14.2 0.4 1.4 9.2 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 KIY45136.1 - 0.063 13.1 2.9 0.51 10.1 0.7 2.5 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KIY45136.1 - 0.18 12.3 0.6 28 5.3 0.1 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF3546 PF12066.8 KIY45137.1 - 6.9e-15 55.2 0.3 6.9e-15 55.2 0.3 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KIY45137.1 - 3.2e-12 47.2 0.0 3.2e-12 47.2 0.0 3.0 4 0 0 4 4 4 1 Arsenite-resistance protein 2 RHINO PF15319.6 KIY45137.1 - 0.0016 18.5 0.4 0.0016 18.5 0.4 2.1 2 0 0 2 2 2 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein DUF4187 PF13821.6 KIY45137.1 - 0.002 17.9 2.5 0.0047 16.7 2.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2 PF00096.26 KIY45137.1 - 0.045 14.2 0.8 0.12 12.9 0.8 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIY45137.1 - 0.21 11.9 2.6 0.38 11.1 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) adh_short PF00106.25 KIY45138.1 - 1.9e-38 131.9 0.0 2.6e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY45138.1 - 3.2e-24 85.8 0.1 4.3e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L27A PF00828.19 KIY45139.1 - 4.1e-33 114.8 0.0 6.5e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_S16 PF00886.19 KIY45139.1 - 0.029 14.4 0.2 0.099 12.7 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S16 Response_reg PF00072.24 KIY45140.1 - 2.5e-23 82.4 0.1 7e-21 74.5 0.1 2.7 1 1 0 1 1 1 1 Response regulator receiver domain CAP_N PF01213.19 KIY45140.1 - 1.9 7.9 9.2 0.5 9.8 0.6 2.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SUI1 PF01253.22 KIY45141.1 - 1.5e-25 89.5 0.5 2.9e-25 88.6 0.5 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF1717 PF05414.11 KIY45141.1 - 0.092 13.2 0.9 0.24 11.8 0.9 1.7 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) Img2 PF05046.14 KIY45141.1 - 0.11 12.8 0.3 0.27 11.6 0.3 1.7 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) PilN_bio_d PF18222.1 KIY45142.1 - 0.045 14.1 0.0 0.062 13.7 0.0 1.2 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain COesterase PF00135.28 KIY45143.1 - 9.9e-56 189.7 0.0 6e-55 187.1 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY45143.1 - 0.0025 17.7 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.10 KIY45143.1 - 0.011 14.9 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) EAF PF09816.9 KIY45144.1 - 1.3e-22 80.0 0.1 2.5e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor ADH_N PF08240.12 KIY45145.1 - 0.00041 20.2 1.3 0.0034 17.2 0.1 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY45145.1 - 0.016 15.1 0.4 0.41 10.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY45145.1 - 0.12 13.4 0.0 0.25 12.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Acyl-CoA_dh_1 PF00441.24 KIY45146.1 - 3.5e-41 140.9 1.8 5.1e-41 140.4 1.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIY45146.1 - 3.9e-29 101.6 1.2 1.6e-28 99.6 0.0 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIY45146.1 - 4.1e-23 81.4 0.0 7.3e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIY45146.1 - 2.5e-21 76.3 0.6 4.2e-21 75.6 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KIY45146.1 - 0.02 15.4 0.7 0.16 12.6 0.7 2.2 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal CGI-121 PF08617.10 KIY45147.1 - 2.2e-41 141.7 0.0 2.5e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF2340 PF10209.9 KIY45148.1 - 6.4e-53 178.3 0.2 7.4e-53 178.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 KIY45148.1 - 0.00025 21.4 0.0 0.00028 21.2 0.0 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain PPR_2 PF13041.6 KIY45149.1 - 5.2e-41 138.6 0.1 1.3e-09 38.1 0.0 13.0 10 2 4 14 14 14 8 PPR repeat family PPR PF01535.20 KIY45149.1 - 6.4e-38 126.4 5.2 0.00018 21.5 0.0 13.6 17 0 0 17 17 17 7 PPR repeat PPR_3 PF13812.6 KIY45149.1 - 5.6e-27 93.6 0.0 1.6e-07 31.3 0.0 8.2 8 0 0 8 8 8 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIY45149.1 - 1.9e-25 88.2 0.0 0.0034 17.1 0.0 11.1 14 0 0 14 14 14 5 PPR repeat PPR_long PF17177.4 KIY45149.1 - 2.7e-17 62.8 1.4 4e-13 49.2 0.1 3.9 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KIY45149.1 - 3.6e-06 27.3 7.1 4.7 8.3 0.0 8.4 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY45149.1 - 0.011 16.2 4.6 3.7 8.1 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat RPM2 PF08579.11 KIY45149.1 - 0.089 13.2 0.1 2.7 8.4 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_16 PF13432.6 KIY45149.1 - 0.1 13.3 15.1 0.3 11.8 0.0 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY45149.1 - 0.62 10.9 7.8 1e+02 4.0 0.8 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat p450 PF00067.22 KIY45150.1 - 1.5e-59 202.0 0.1 1.9e-57 195.0 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 zf-RING_2 PF13639.6 KIY45151.1 - 8.2e-07 29.3 9.3 1.7e-06 28.3 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KIY45151.1 - 0.00025 21.1 5.2 0.00055 20.1 5.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KIY45151.1 - 0.00041 20.3 2.4 0.00088 19.3 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY45151.1 - 0.0025 18.1 7.6 0.0054 17.0 7.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KIY45151.1 - 0.014 15.0 5.3 0.029 14.0 5.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2267 PF10025.9 KIY45151.1 - 0.018 15.4 1.1 1.3 9.4 0.1 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2267) RINGv PF12906.7 KIY45151.1 - 0.033 14.3 7.0 0.073 13.2 7.0 1.6 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.22 KIY45151.1 - 0.093 12.6 4.3 0.046 13.6 2.0 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 KIY45151.1 - 0.17 11.7 8.7 0.35 10.8 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KIY45151.1 - 0.36 11.2 7.6 0.72 10.2 7.6 1.5 1 0 0 1 1 1 0 RING-like domain Zf_RING PF16744.5 KIY45151.1 - 0.4 10.8 3.6 0.94 9.6 3.6 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4 PF00097.25 KIY45151.1 - 1.4 8.9 9.6 2.5 8.0 9.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) dCMP_cyt_deam_1 PF00383.23 KIY45152.1 - 5.4e-22 77.6 0.1 8.1e-22 77.0 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIY45152.1 - 9.4e-22 77.3 0.1 2.1e-21 76.1 0.1 1.5 1 1 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KIY45152.1 - 0.00048 20.2 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 KIY45152.1 - 0.0042 17.2 0.0 0.0059 16.7 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 APOBEC3 PF18771.1 KIY45152.1 - 0.0068 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 NAD1 PF18778.1 KIY45152.1 - 0.012 15.8 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 KIY45152.1 - 0.016 15.3 0.7 0.044 13.9 0.7 1.8 1 1 0 1 1 1 0 Bd3614-like deaminase Inv-AAD PF18785.1 KIY45152.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase APOBEC_N PF08210.11 KIY45152.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 KIY45152.1 - 0.15 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Adap_comp_sub PF00928.21 KIY45153.1 - 3.2e-19 69.3 0.0 5.2e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIY45153.1 - 0.00087 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2076 PF09849.9 KIY45153.1 - 0.25 11.4 3.2 0.38 10.8 3.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NCBP3 PF10309.9 KIY45155.1 - 1.3e-11 44.1 0.0 2.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 KIY45155.1 - 0.00017 22.1 11.1 0.011 16.3 2.0 2.4 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 Coilin_N PF15862.5 KIY45156.1 - 1.8e-10 40.8 0.4 1.8e-10 40.8 0.4 2.3 2 0 0 2 2 2 1 Coilin N-terminus UPF0561 PF10573.9 KIY45156.1 - 0.049 13.7 1.4 0.17 12.0 1.4 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 DUF1754 PF08555.10 KIY45156.1 - 5.5 7.9 11.0 6.8 7.6 0.5 2.7 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) GTP_EFTU PF00009.27 KIY45157.1 - 3.9e-35 121.2 0.4 9.1e-34 116.7 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KIY45157.1 - 6.8e-20 71.2 0.0 2.8e-19 69.2 0.0 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KIY45157.1 - 2.5e-15 56.6 5.5 3.8e-10 40.0 0.1 3.9 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY45157.1 - 3.2e-07 30.4 0.1 6.3e-06 26.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KIY45157.1 - 3.6e-05 23.6 0.1 0.00011 22.1 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 KIY45157.1 - 0.00025 21.2 0.0 0.0006 20.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KIY45157.1 - 0.021 14.6 0.0 0.072 12.9 0.0 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KIY45157.1 - 0.052 13.8 0.6 0.82 9.9 0.3 2.7 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 KIY45157.1 - 0.083 12.5 0.0 0.35 10.5 0.0 2.1 1 1 0 1 1 1 0 Ras family Chordopox_A30L PF06015.12 KIY45158.1 - 0.019 14.8 3.3 0.085 12.7 3.3 2.2 1 1 0 1 1 1 0 Chordopoxvirus A30L protein BSP_II PF05432.11 KIY45158.1 - 1.2 8.8 8.7 1.6 8.4 8.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ATP-synt_S1 PF05827.12 KIY45159.1 - 0.0056 16.5 0.1 0.0087 15.9 0.1 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Tad PF13400.6 KIY45159.1 - 1.6 9.1 3.7 16 5.9 0.0 2.5 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Sec63 PF02889.16 KIY45161.1 - 2e-17 63.2 0.0 7.7e-17 61.3 0.0 1.9 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 KIY45161.1 - 5e-15 55.4 1.0 1e-14 54.4 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain TAP35_44 PF07265.11 KIY45163.1 - 0.026 14.6 1.0 0.033 14.2 0.1 1.6 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 Cyclin_N PF00134.23 KIY45164.1 - 4.6e-17 62.0 0.3 5.5e-17 61.7 0.3 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY45164.1 - 2.6e-12 47.4 0.0 2.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin SEP PF08059.13 KIY45165.1 - 5.6e-24 84.5 0.0 1e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KIY45165.1 - 1.5e-14 53.9 0.0 2.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 UBX domain CMAS PF02353.20 KIY45166.1 - 4.3e-57 193.5 0.0 6.1e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIY45166.1 - 2.7e-08 34.4 0.0 5.6e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY45166.1 - 2.4e-06 28.1 0.0 4.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY45166.1 - 0.00018 21.4 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY45166.1 - 0.0049 17.6 0.0 0.009 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KIY45166.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Arf PF00025.21 KIY45167.1 - 2.1e-66 222.7 0.0 2.4e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIY45167.1 - 1.2e-12 47.6 0.5 7e-07 28.7 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KIY45167.1 - 1.9e-09 37.8 0.0 3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIY45167.1 - 2.3e-08 33.7 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KIY45167.1 - 1.9e-07 30.7 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KIY45167.1 - 4.2e-07 29.7 0.0 5.5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KIY45167.1 - 1.7e-06 28.1 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY45167.1 - 0.038 14.5 0.0 0.071 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KIY45167.1 - 0.051 13.3 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PNK3P PF08645.11 KIY45168.1 - 2.2e-48 164.0 0.0 1.3e-47 161.5 0.0 1.9 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KIY45168.1 - 5.2e-17 62.3 0.0 3e-14 53.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain LNS2 PF08235.13 KIY45168.1 - 0.0002 20.9 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) KdpC PF02669.15 KIY45168.1 - 0.078 12.8 0.0 1.4 8.7 0.0 2.2 1 1 0 1 1 1 0 K+-transporting ATPase, c chain KTI12 PF08433.10 KIY45168.1 - 0.15 11.5 0.0 3.9 6.9 0.0 2.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Med13_C PF06333.12 KIY45169.1 - 4.4e-56 190.5 6.0 4.4e-56 190.5 6.0 3.4 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KIY45169.1 - 1.6e-22 80.3 0.0 3.7e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Kinesin PF00225.23 KIY45170.1 - 1.8e-99 332.9 0.0 2.8e-99 332.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 KIY45170.1 - 1.3e-39 136.2 5.8 3.1e-31 108.9 1.9 2.8 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 KIY45170.1 - 1.7e-39 136.0 0.0 5.4e-39 134.3 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 KIY45170.1 - 3.7e-13 49.6 0.0 2.1e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 KIY45170.1 - 3.9e-10 40.2 0.0 1.5e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 PH domain FHA PF00498.26 KIY45170.1 - 2.2e-07 31.1 0.0 1e-06 29.0 0.0 2.3 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KIY45170.1 - 0.00041 20.7 1.3 0.0011 19.3 0.2 2.4 2 0 0 2 2 2 1 Kinesin protein 1B EAP30 PF04157.16 KIY45170.1 - 0.012 14.9 1.2 0.023 14.0 0.4 1.9 2 0 0 2 2 2 0 EAP30/Vps36 family Glyco_hydro_47 PF01532.20 KIY45171.1 - 3.8e-106 355.7 0.0 4.3e-106 355.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 KIY45171.1 - 0.26 10.7 5.8 0.32 10.5 0.1 2.8 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 DUF2433 PF10360.9 KIY45172.1 - 3.9e-42 143.2 0.0 8.2e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 KIY45172.1 - 6.7e-06 25.8 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KIY45172.1 - 0.051 14.1 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY45172.1 - 0.055 13.7 0.0 0.28 11.4 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain NAM-associated PF14303.6 KIY45172.1 - 6.9 7.4 10.9 15 6.2 10.9 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain p450 PF00067.22 KIY45174.1 - 2.2e-51 175.1 0.0 2.6e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIY45176.1 - 5.4e-07 30.2 6.8 0.00013 22.7 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY45176.1 - 0.00011 22.4 0.6 0.15 12.4 0.0 4.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BRK PF07533.16 KIY45176.1 - 0.016 14.8 0.5 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 BRK domain DUF2833 PF11090.8 KIY45176.1 - 0.071 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) Lactonase PF10282.9 KIY45176.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DUF1930 PF09122.10 KIY45176.1 - 0.18 11.8 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) ICMT PF04140.14 KIY45177.1 - 1.8e-08 34.6 0.2 1.5e-07 31.7 0.2 2.3 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY45177.1 - 8.8e-06 26.1 0.5 8.3e-05 22.9 0.5 2.2 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIY45177.1 - 0.00051 18.9 0.0 0.00092 18.1 0.0 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family SLC3A2_N PF16028.5 KIY45177.1 - 0.0018 17.8 0.3 0.0018 17.8 0.3 2.0 2 0 0 2 2 2 1 Solute carrier family 3 member 2 N-terminus DUF1700 PF08006.11 KIY45177.1 - 2.6 7.6 4.9 0.28 10.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) S4 PF01479.25 KIY45178.1 - 6.9e-11 41.7 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KIY45178.1 - 3e-09 37.7 0.5 5.2e-09 36.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain RRM_1 PF00076.22 KIY45179.1 - 1.3e-38 130.7 0.0 5.3e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY45179.1 - 2.9e-05 24.1 0.0 0.22 11.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 KIY45179.1 - 0.00016 21.5 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KIY45179.1 - 0.12 12.4 0.0 0.67 10.0 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KIY45179.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain HTH_Crp_2 PF13545.6 KIY45180.1 - 0.077 13.0 0.4 0.67 10.0 0.3 2.1 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_30 PF13556.6 KIY45180.1 - 0.096 12.5 3.7 1.2 9.0 0.5 2.4 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain zf-MYND PF01753.18 KIY45183.1 - 3.3e-09 36.7 14.8 5.8e-09 35.9 14.8 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KIY45183.1 - 0.026 14.4 9.4 0.045 13.6 9.4 1.3 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 KIY45183.1 - 1.2 9.5 12.0 2 8.8 12.0 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding GPI-anchored PF10342.9 KIY45184.1 - 0.00029 21.5 0.0 0.00037 21.2 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family E1-E2_ATPase PF00122.20 KIY45185.1 - 1.2e-44 152.1 0.1 1.2e-44 152.1 0.1 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIY45185.1 - 9.2e-40 137.2 2.5 2.2e-39 135.9 2.5 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIY45185.1 - 9.4e-29 99.7 4.4 8.9e-12 45.3 0.3 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.7 KIY45185.1 - 7.3e-06 26.5 0.0 2.5e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIY45185.1 - 0.0011 18.8 0.2 0.0023 17.7 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4162 PF13732.6 KIY45185.1 - 0.036 14.8 0.1 8.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) GPI-anchored PF10342.9 KIY45186.1 - 9.1e-09 36.0 0.3 1.3e-08 35.5 0.3 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KIY45186.1 - 0.0018 18.0 0.3 0.0021 17.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) FHA PF00498.26 KIY45187.1 - 1.1e-16 61.0 0.0 1.8e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIY45187.1 - 4.9e-07 30.0 0.0 2e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CDC45 PF02724.14 KIY45187.1 - 5.8 5.1 12.1 6.9 4.8 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SKN1 PF03935.15 KIY45188.1 - 3.4e-186 619.5 8.5 4e-186 619.3 8.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Rrp40_N PF18311.1 KIY45189.1 - 2.5e-13 49.7 0.1 4.7e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 KIY45189.1 - 8.1e-13 48.5 1.6 9.1e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 KH domain Psu PF07455.11 KIY45189.1 - 0.06 12.9 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) Mur_ligase_M PF08245.12 KIY45190.1 - 1.5e-06 28.3 0.0 5.3e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KIY45190.1 - 0.12 12.6 0.0 0.68 10.2 0.0 2.2 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Zn_clus PF00172.18 KIY45191.1 - 5.7e-09 36.0 7.3 1.1e-08 35.1 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY45191.1 - 5.6e-07 28.9 0.0 9.4e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sel_put PF04328.13 KIY45192.1 - 0.018 15.0 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein, putative Fer2_3 PF13085.6 KIY45193.1 - 1.3e-33 115.3 0.1 2e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KIY45193.1 - 3.7e-10 40.2 7.1 3.7e-10 40.2 7.1 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KIY45193.1 - 3.7e-07 30.5 7.6 3.7e-07 30.5 7.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIY45193.1 - 6e-07 29.5 3.9 6e-07 29.5 3.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIY45193.1 - 0.00072 20.1 4.6 0.00072 20.1 4.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KIY45193.1 - 0.0037 17.2 0.5 0.0037 17.2 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_16 PF13484.6 KIY45193.1 - 4.5 8.3 12.3 0.94 10.5 7.3 2.4 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fungal_trans PF04082.18 KIY45194.1 - 3.4e-08 32.8 0.4 6.9e-08 31.8 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Carn_acyltransf PF00755.20 KIY45195.1 - 3.1e-197 656.8 0.0 3.5e-197 656.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ctr PF04145.15 KIY45197.1 - 2.5e-18 67.1 0.8 4.1e-18 66.4 0.8 1.3 1 0 0 1 1 1 1 Ctr copper transporter family F-box-like PF12937.7 KIY45198.1 - 1.2e-11 44.4 0.5 1.2e-11 44.4 0.5 2.3 2 0 0 2 2 2 1 F-box-like DUF764 PF05561.11 KIY45198.1 - 0.23 11.3 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) E1_dh PF00676.20 KIY45199.1 - 4.7e-81 272.0 0.0 5.5e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component mRNA_triPase PF02940.15 KIY45200.1 - 2.9e-44 151.4 0.1 3.5e-44 151.1 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Peptidase_C48 PF02902.19 KIY45202.1 - 6.3e-06 26.2 0.1 7.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YscK PF06578.12 KIY45202.1 - 0.15 11.5 0.0 0.18 11.3 0.0 1.0 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Peptidase_C48 PF02902.19 KIY45203.1 - 3.8e-12 46.5 0.0 4.8e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLATT_2 PF18183.1 KIY45203.1 - 0.037 13.8 0.0 0.043 13.6 0.0 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 2 LuxS PF02664.15 KIY45203.1 - 0.081 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) DUF3375 PF11855.8 KIY45203.1 - 0.13 11.1 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) MIOX PF05153.15 KIY45204.1 - 0.018 14.6 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Myo-inositol oxygenase Zip PF02535.22 KIY45205.1 - 6.1e-31 107.9 11.3 5.9e-30 104.6 11.3 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1772 PF08592.11 KIY45205.1 - 0.78 10.1 6.9 1.1 9.5 2.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) UPF0242 PF06785.11 KIY45206.1 - 0.071 13.2 0.3 0.071 13.2 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-K PF11802.8 KIY45206.1 - 0.82 9.2 5.2 3.3 7.2 5.1 2.0 1 1 0 1 1 1 0 Centromere-associated protein K DUF4407 PF14362.6 KIY45206.1 - 0.9 8.8 6.2 1.6 8.0 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Med9 PF07544.13 KIY45206.1 - 4.9 7.3 7.3 18 5.5 0.2 3.7 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Aminotran_1_2 PF00155.21 KIY45207.1 - 1.5e-44 152.7 0.0 1.9e-38 132.6 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIY45207.1 - 0.00071 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KIY45207.1 - 0.0022 16.8 0.0 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain TMEM171 PF15471.6 KIY45208.1 - 0.28 10.1 0.4 0.43 9.5 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 F-box-like PF12937.7 KIY45209.1 - 1.4e-05 24.9 2.1 0.00064 19.6 0.2 2.7 2 0 0 2 2 2 2 F-box-like F-box-like PF12937.7 KIY45210.1 - 2e-08 34.0 0.3 2e-08 34.0 0.3 2.7 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KIY45210.1 - 6.9e-06 26.3 7.4 0.029 14.8 0.1 6.0 4 2 3 7 7 7 2 Leucine Rich repeats (2 copies) PQ-loop PF04193.14 KIY45211.1 - 7.4e-32 108.9 16.4 6.2e-18 64.3 1.3 3.1 3 0 0 3 3 3 2 PQ loop repeat DUF4231 PF14015.6 KIY45211.1 - 0.19 12.2 2.8 0.89 10.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF5090 PF17009.5 KIY45211.1 - 0.55 10.2 3.0 15 5.4 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Pkinase PF00069.25 KIY45212.1 - 2.7e-54 184.3 0.0 3.3e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45212.1 - 4.1e-29 101.6 0.0 4.7e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY45212.1 - 6.1e-08 32.3 0.0 1.8e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KIY45212.1 - 0.016 14.2 0.0 0.21 10.5 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KIY45212.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_N PF02463.19 KIY45213.1 - 1.6e-24 86.5 0.0 9.5e-24 84.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIY45213.1 - 8.2e-11 42.2 1.3 6.5e-10 39.3 0.0 2.7 2 2 1 3 3 2 1 AAA ATPase domain AAA_23 PF13476.6 KIY45213.1 - 1e-10 42.5 22.8 1e-10 42.5 22.8 4.6 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.6 KIY45213.1 - 7.3e-07 29.3 0.5 0.00097 19.0 0.2 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY45213.1 - 0.00063 19.4 0.0 0.002 17.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain Syntaxin PF00804.25 KIY45213.1 - 0.0011 18.7 8.3 0.0011 18.7 8.3 4.7 3 1 1 4 4 4 1 Syntaxin Linker_histone PF00538.19 KIY45213.1 - 0.061 13.7 0.7 0.21 12.0 0.7 1.9 1 0 0 1 1 1 0 linker histone H1 and H5 family DUF3584 PF12128.8 KIY45213.1 - 0.064 10.8 72.2 0.013 13.1 32.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KIY45213.1 - 0.11 11.4 70.9 0.13 11.1 16.2 4.5 2 2 2 4 4 4 0 Spc7 kinetochore protein ABC_tran PF00005.27 KIY45213.1 - 0.15 12.6 0.1 0.15 12.6 0.1 5.2 4 2 0 4 4 2 0 ABC transporter DUF1664 PF07889.12 KIY45213.1 - 0.44 10.6 45.6 0.27 11.3 1.6 6.9 3 2 3 7 7 7 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 KIY45213.1 - 1.3 7.6 57.2 2.3 6.8 23.3 3.8 4 1 0 4 4 4 0 AAA domain Mce4_CUP1 PF11887.8 KIY45213.1 - 1.7 8.0 10.6 0.19 11.1 0.2 3.3 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative MutS_V PF00488.21 KIY45215.1 - 5.9e-40 137.3 0.0 1.4e-38 132.9 0.0 2.4 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIY45215.1 - 1.6e-29 103.5 0.0 4.6e-29 102.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain III DUF2066 PF09839.9 KIY45217.1 - 0.0031 17.0 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2066) DUF4218 PF13960.6 KIY45217.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Cep57_MT_bd PF06657.13 KIY45217.1 - 0.051 14.0 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DEAD PF00270.29 KIY45218.1 - 1.5e-37 129.0 0.1 2.4e-37 128.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY45218.1 - 1.9e-09 37.8 0.0 7.6e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY45218.1 - 1.7e-07 31.4 0.0 2.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY45218.1 - 0.033 14.5 0.2 0.1 12.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain Cu_amine_oxidN3 PF02728.16 KIY45218.1 - 0.11 12.9 0.0 0.62 10.5 0.0 2.2 3 0 0 3 3 3 0 Copper amine oxidase, N3 domain Glyco_hydro_43 PF04616.14 KIY45219.1 - 2.1e-15 56.8 3.5 3.8e-15 56.0 3.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KIY45219.1 - 0.0052 17.1 2.1 0.014 15.7 2.1 1.8 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) MFS_1 PF07690.16 KIY45220.1 - 2e-41 142.1 46.0 3.2e-29 102.0 17.0 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY45220.1 - 4e-06 25.9 23.0 4.6e-05 22.5 10.0 3.8 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KIY45220.1 - 7.6e-06 25.0 20.4 0.00042 19.3 0.4 3.2 2 1 1 3 3 3 2 MFS_1 like family Deltameth_res PF16020.5 KIY45220.1 - 0.36 10.7 7.9 9 6.3 0.1 4.2 4 0 0 4 4 4 0 Deltamethrin resistance CPP1-like PF11833.8 KIY45220.1 - 1.1 8.9 5.3 1.6 8.3 1.9 2.7 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fapy_DNA_glyco PF01149.24 KIY45221.1 - 1.1e-25 90.5 0.0 1.5e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KIY45221.1 - 6.3e-20 71.0 0.0 1.1e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KIY45221.1 - 0.27 10.0 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) VIT PF08487.10 KIY45222.1 - 1.5e-26 92.8 0.0 2.6e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIY45222.1 - 2.7e-19 69.6 0.0 6.2e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIY45222.1 - 7.6e-11 42.6 0.0 2.9e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIY45222.1 - 1e-07 32.6 0.0 4.6e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KIY45222.1 - 1.1e-07 31.5 0.1 2.1e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.6 KIY45222.1 - 8.1e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Mito_carr PF00153.27 KIY45223.1 - 5e-35 119.3 0.1 8.1e-13 48.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 KIY45224.1 - 6.7e-37 126.9 0.1 1.2e-36 126.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY45224.1 - 3.7e-26 91.7 0.2 7.1e-25 87.5 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY45224.1 - 5.2e-09 36.3 0.0 8.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit LSM PF01423.22 KIY45225.1 - 6.2e-14 51.4 0.2 8.1e-14 51.1 0.2 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIY45225.1 - 0.003 17.2 0.5 0.0052 16.4 0.5 1.5 1 0 0 1 1 1 1 Hfq protein DHC_N2 PF08393.13 KIY45226.1 - 2e-116 389.4 8.6 2e-116 389.4 8.6 3.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 KIY45226.1 - 4.4e-114 380.8 0.0 3.4e-113 377.9 0.0 2.6 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 KIY45226.1 - 2.2e-73 246.0 1.0 2.2e-73 246.0 1.0 3.2 4 1 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KIY45226.1 - 3.4e-66 223.2 0.0 9.3e-66 221.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KIY45226.1 - 1.7e-51 175.3 0.0 5.7e-51 173.6 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KIY45226.1 - 3.5e-42 144.0 0.0 1.2e-36 126.0 0.0 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 KIY45226.1 - 1.3e-41 142.7 4.0 2.4e-41 141.9 4.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KIY45226.1 - 1.3e-36 125.9 0.0 2.5e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KIY45226.1 - 4.3e-29 101.0 0.0 9.1e-28 96.8 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KIY45226.1 - 2.7e-28 98.7 0.0 2.2e-13 50.4 0.0 5.7 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KIY45226.1 - 5.4e-18 65.3 1.6 1.4e-16 60.7 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KIY45226.1 - 2.4e-11 44.2 0.0 0.00074 20.0 0.0 4.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIY45226.1 - 3.2e-11 43.7 0.0 0.0061 16.8 0.0 4.9 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.6 KIY45226.1 - 5e-11 42.9 0.1 0.076 13.2 0.0 5.1 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 KIY45226.1 - 1.8e-08 35.0 0.0 0.66 10.3 0.0 5.3 4 0 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 KIY45226.1 - 7.4e-07 29.8 0.8 0.13 12.9 0.0 4.9 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 KIY45226.1 - 2.8e-06 26.6 0.0 0.0037 16.4 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 KIY45226.1 - 9e-06 25.2 0.5 0.65 9.4 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KIY45226.1 - 2.3e-05 24.8 0.3 0.3 11.4 0.0 4.6 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 KIY45226.1 - 5e-05 22.8 0.0 0.35 10.2 0.0 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KIY45226.1 - 0.00087 19.1 0.1 0.73 9.5 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.6 KIY45226.1 - 0.0015 18.3 0.1 0.85 9.4 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIY45226.1 - 0.0024 18.4 0.4 13 6.3 0.0 4.6 4 0 0 4 4 3 0 ABC transporter AAA_lid_1 PF17857.1 KIY45226.1 - 0.0024 18.1 0.0 0.0024 18.1 0.0 2.8 3 0 0 3 3 1 1 AAA+ lid domain Rad17 PF03215.15 KIY45226.1 - 0.0058 16.6 0.0 25 4.7 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_21 PF13304.6 KIY45226.1 - 0.012 15.4 0.0 9.2 6.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KIY45226.1 - 0.015 14.8 0.0 0.54 9.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KIY45226.1 - 0.031 14.7 0.0 14 6.1 0.0 3.7 3 0 0 3 3 3 0 RNA helicase TsaE PF02367.17 KIY45226.1 - 0.034 14.1 0.4 16 5.5 0.0 3.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KIY45226.1 - 0.04 13.6 0.5 22 4.7 0.0 3.7 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 KIY45226.1 - 0.053 13.5 0.5 35 4.3 0.0 4.1 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KIY45226.1 - 0.053 13.3 0.1 3 7.6 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 KIY45226.1 - 0.11 12.1 1.0 42 3.7 0.1 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 KIY45226.1 - 0.15 11.8 12.7 1.4 8.7 0.0 4.4 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.9 KIY45226.1 - 0.16 11.7 0.3 12 5.7 0.1 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation LOH1CR12 PF10158.9 KIY45226.1 - 0.27 11.3 11.8 0.44 10.6 0.8 3.9 3 0 0 3 3 2 0 Tumour suppressor protein NACHT PF05729.12 KIY45226.1 - 0.4 10.6 2.7 39 4.1 0.1 4.2 4 0 0 4 4 3 0 NACHT domain FAD_binding_4 PF01565.23 KIY45227.1 - 1.2e-19 70.4 0.2 2.6e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY45227.1 - 1.2e-09 38.1 0.8 2.7e-09 37.0 0.8 1.6 1 0 0 1 1 1 1 Berberine and berberine like L51_S25_CI-B8 PF05047.16 KIY45228.1 - 1.2e-10 41.1 0.2 2e-10 40.4 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MRP_L53 PF10780.9 KIY45228.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 HAD_2 PF13419.6 KIY45229.1 - 2.4e-16 60.3 0.0 3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY45229.1 - 8.1e-11 42.6 0.0 1.2e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY45229.1 - 2.1e-08 34.1 0.0 3.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like GYF PF02213.16 KIY45231.1 - 1.1e-16 60.2 0.3 1.4e-16 59.9 0.3 1.1 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KIY45231.1 - 0.088 12.6 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 GYF domain 2 Acatn PF13000.7 KIY45232.1 - 7.9e-147 490.1 28.2 5.1e-72 243.1 17.5 3.7 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 p450 PF00067.22 KIY45233.1 - 1e-56 192.7 0.0 1.4e-56 192.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY45234.1 - 3.7e-52 177.6 0.0 4.5e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ACD PF16671.5 KIY45234.1 - 0.041 12.2 0.0 0.068 11.5 0.0 1.3 1 0 0 1 1 1 0 Actin cross-linking domain Fer2_4 PF13510.6 KIY45234.1 - 0.073 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain NIF PF03031.18 KIY45234.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase HATPase_c PF02518.26 KIY45235.1 - 4.2e-29 101.3 0.0 9.8e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIY45235.1 - 6.8e-19 68.1 0.0 8.4e-18 64.6 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.6 KIY45235.1 - 2.7e-14 53.9 1.2 3.7e-13 50.2 0.7 2.8 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.25 KIY45235.1 - 1.1e-09 38.2 1.3 8.1e-09 35.4 0.3 3.2 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.25 KIY45235.1 - 4.1e-07 29.6 0.0 7.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 KIY45235.1 - 4.4e-05 24.1 0.0 0.00018 22.1 0.0 2.1 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 KIY45235.1 - 0.00059 19.7 0.1 0.0027 17.6 0.0 2.2 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NACHT PF05729.12 KIY45235.1 - 0.0064 16.4 1.1 0.065 13.1 1.1 2.5 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 KIY45235.1 - 0.012 15.7 0.2 3.8 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KIY45235.1 - 0.055 12.7 0.2 0.33 10.1 0.2 2.0 1 1 0 1 1 1 0 NB-ARC domain TPR_12 PF13424.6 KIY45235.1 - 0.055 13.8 0.0 0.055 13.8 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat RuvB_N PF05496.12 KIY45235.1 - 0.15 11.8 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CwfJ_C_1 PF04677.15 KIY45236.1 - 8.8e-31 106.3 0.0 1.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 KIY45236.1 - 1e-23 82.7 22.2 1.2e-10 41.0 3.3 3.5 3 0 0 3 3 3 3 Zinc knuckle CwfJ_C_2 PF04676.14 KIY45236.1 - 2.8e-10 40.9 0.0 6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 KIY45236.1 - 3.3e-10 39.6 11.2 0.0027 17.7 0.1 3.6 3 0 0 3 3 3 3 Zinc knuckle HIT PF01230.23 KIY45236.1 - 0.051 14.3 0.0 0.096 13.4 0.0 1.4 1 0 0 1 1 1 0 HIT domain zf-CCHC_3 PF13917.6 KIY45236.1 - 2.2 8.3 6.1 17 5.5 0.2 3.5 2 1 1 3 3 3 0 Zinc knuckle Kinesin PF00225.23 KIY45237.1 - 1.8e-81 273.7 0.0 3.1e-81 272.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY45237.1 - 3.1e-15 56.4 0.0 2.9e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding CENP-H PF05837.12 KIY45237.1 - 1.9 8.9 8.9 0.096 13.1 1.8 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF883 PF05957.13 KIY45238.1 - 0.029 14.9 6.5 0.029 14.9 6.5 1.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) tRNA-synt_1e PF01406.19 KIY45238.1 - 0.03 13.7 0.5 0.034 13.5 0.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain YtxH PF12732.7 KIY45238.1 - 0.18 12.4 14.4 0.18 12.3 10.1 2.0 1 1 1 2 2 2 0 YtxH-like protein Borrelia_P83 PF05262.11 KIY45238.1 - 0.32 9.5 9.2 0.32 9.4 9.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP-synt_B PF00430.18 KIY45238.1 - 0.33 11.0 9.0 0.35 11.0 8.2 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) MID_MedPIWI PF18296.1 KIY45238.1 - 0.57 9.9 4.1 0.6 9.9 4.1 1.0 1 0 0 1 1 1 0 MID domain of medPIWI DDHD PF02862.17 KIY45238.1 - 2.5 8.2 5.5 2.6 8.2 5.5 1.0 1 0 0 1 1 1 0 DDHD domain CtnDOT_TraJ PF07863.11 KIY45238.1 - 7.1 7.4 5.7 8.5 7.1 2.6 2.1 1 1 1 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Presenilin PF01080.17 KIY45238.1 - 9.9 4.8 6.7 9.7 4.8 6.7 1.0 1 0 0 1 1 1 0 Presenilin MutS_V PF00488.21 KIY45240.1 - 7.5e-52 176.1 0.1 3.2e-51 174.0 0.0 2.1 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KIY45240.1 - 2.4e-33 116.0 1.1 2.4e-33 116.0 1.1 2.0 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KIY45240.1 - 2e-06 28.1 0.0 1e-05 25.8 0.0 2.3 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KIY45240.1 - 4.4e-05 23.7 0.0 0.00017 21.8 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV Epsilon_antitox PF08998.11 KIY45240.1 - 0.1 12.9 0.6 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial epsilon antitoxin APH PF01636.23 KIY45243.1 - 5.3e-13 49.5 4.5 9.5e-13 48.6 4.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY45243.1 - 1.3e-06 28.2 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KIY45243.1 - 0.012 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain HipA_C PF07804.12 KIY45243.1 - 0.019 14.7 0.0 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 HipA-like C-terminal domain RIO1 PF01163.22 KIY45243.1 - 0.04 13.5 0.3 0.14 11.8 0.2 1.8 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KIY45243.1 - 0.075 12.4 1.3 0.2 11.0 0.7 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KIY45243.1 - 0.093 12.0 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 KIY45244.1 - 2.3e-71 240.3 0.0 2.7e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45244.1 - 4e-36 124.6 0.0 5.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY45244.1 - 0.00014 20.9 0.0 0.32 9.9 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KIY45244.1 - 0.008 15.5 0.7 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY45244.1 - 0.038 13.9 1.9 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY45244.1 - 0.068 12.5 0.1 0.33 10.3 0.1 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Utp12 PF04003.12 KIY45245.1 - 6.1e-25 87.6 0.1 1e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KIY45245.1 - 2.3e-06 28.2 3.5 0.11 13.4 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY45245.1 - 0.00014 22.1 0.0 0.079 13.3 0.1 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KIY45246.1 - 4.2e-23 81.7 0.1 6.9e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KIY45246.1 - 0.00037 20.7 0.0 0.034 14.4 0.1 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY45246.1 - 0.0025 18.6 2.1 0.4 11.6 0.4 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Bromodomain PF00439.25 KIY45249.1 - 1.1e-21 76.7 0.1 2.4e-15 56.4 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KIY45249.1 - 9.6e-12 44.8 0.0 2.3e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 BAH domain Zip PF02535.22 KIY45249.1 - 1.3 8.2 4.6 2 7.5 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CS PF04969.16 KIY45251.1 - 1.3e-05 26.1 0.0 2.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 KIY45251.1 - 0.83 10.3 15.2 1.2 9.7 15.2 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region BC10 PF06726.12 KIY45252.1 - 1.9e-05 24.8 9.4 3.2e-05 24.1 9.4 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 WD40 PF00400.32 KIY45253.1 - 5.5e-31 106.1 11.3 7.3e-06 26.6 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KIY45253.1 - 5.6e-09 35.2 1.7 0.0005 18.9 0.0 3.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIY45253.1 - 0.0076 16.5 0.0 18 5.7 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY45253.1 - 0.024 14.0 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain GlnD_UR_UTase PF08335.11 KIY45253.1 - 0.026 14.6 1.4 0.056 13.5 1.4 1.5 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase Nup88 PF10168.9 KIY45253.1 - 0.063 11.1 0.0 1.8 6.2 0.8 2.0 2 0 0 2 2 2 0 Nuclear pore component EzrA PF06160.12 KIY45253.1 - 0.069 11.3 3.4 0.098 10.8 3.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF5046 PF16465.5 KIY45253.1 - 0.097 12.1 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) ADIP PF11559.8 KIY45253.1 - 0.28 11.3 7.8 0.055 13.6 4.2 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KIY45253.1 - 1.3 9.5 6.2 2.5 8.7 6.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KIY45253.1 - 1.4 8.8 3.6 2.7 7.8 3.6 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4695 PF15766.5 KIY45253.1 - 2.6 8.3 5.8 1.4 9.2 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4695) MPP6 PF10175.9 KIY45254.1 - 0.056 14.0 0.1 0.091 13.3 0.1 1.6 1 1 0 1 1 1 0 M-phase phosphoprotein 6 SRP9-21 PF05486.12 KIY45255.1 - 1.9e-12 47.4 0.6 7.2e-11 42.3 0.6 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Fe-S_assembly PF04384.13 KIY45255.1 - 0.037 14.6 0.0 0.058 14.0 0.0 1.4 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Stevor PF17410.2 KIY45256.1 - 5.5e-06 26.1 3.5 9.4e-06 25.4 3.5 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame VSP PF03302.13 KIY45256.1 - 0.0014 17.6 2.9 0.0029 16.5 2.9 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Mid2 PF04478.12 KIY45256.1 - 0.0031 17.4 0.7 0.0031 17.4 0.7 2.2 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor Insulin_TMD PF17870.1 KIY45256.1 - 0.019 15.0 0.3 0.035 14.2 0.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Amnionless PF14828.6 KIY45256.1 - 0.019 13.8 0.3 0.034 13.0 0.3 1.3 1 0 0 1 1 1 0 Amnionless RIFIN PF02009.16 KIY45256.1 - 0.048 13.5 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Rifin Syndecan PF01034.20 KIY45256.1 - 0.053 13.5 1.4 0.11 12.4 1.4 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 KIY45256.1 - 0.062 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CcmD PF04995.14 KIY45256.1 - 0.07 13.2 2.7 0.14 12.3 2.7 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4381 PF14316.6 KIY45256.1 - 0.085 13.1 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FixQ PF05545.11 KIY45256.1 - 0.086 12.8 0.6 0.23 11.4 0.6 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ EphA2_TM PF14575.6 KIY45256.1 - 0.13 13.2 0.1 0.42 11.5 0.0 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 KIY45256.1 - 0.23 11.1 0.1 0.44 10.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family SKG6 PF08693.10 KIY45256.1 - 1.9 7.9 5.6 4.9 6.6 5.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Npa1 PF11707.8 KIY45257.1 - 9.5e-87 291.5 0.2 3.4e-85 286.4 0.0 2.9 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KIY45257.1 - 4e-55 186.5 4.0 4e-55 186.5 4.0 3.6 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Ribosomal_S14 PF00253.21 KIY45258.1 - 2.2e-14 52.9 3.2 2.6e-14 52.7 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e bZIP_1 PF00170.21 KIY45259.1 - 0.073 13.2 1.7 0.39 10.8 0.0 2.9 3 0 0 3 3 3 0 bZIP transcription factor Nnf1 PF03980.14 KIY45259.1 - 0.098 13.1 0.5 1.1 9.6 0.1 2.6 2 0 0 2 2 2 0 Nnf1 DUF4763 PF15960.5 KIY45259.1 - 0.21 10.9 2.0 0.2 10.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DivIC PF04977.15 KIY45259.1 - 8.3 6.3 7.3 33 4.4 1.2 3.1 2 1 1 3 3 3 0 Septum formation initiator SprT-like PF10263.9 KIY45260.1 - 9.5e-28 96.3 0.1 1.9e-27 95.3 0.1 1.5 1 0 0 1 1 1 1 SprT-like family Tox-MPTase2 PF15638.6 KIY45260.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 2 ARL17 PF15840.5 KIY45261.1 - 0.027 14.8 0.3 0.15 12.4 0.0 2.0 1 1 1 2 2 2 0 ADP-ribosylation factor-like protein 17 DHO_dh PF01180.21 KIY45262.1 - 1.9e-16 60.2 0.0 2.9e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase BTB PF00651.31 KIY45263.1 - 0.0079 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TRAPP PF04051.16 KIY45264.1 - 1.6e-43 147.9 0.0 1.9e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PI-PLC-X PF00388.19 KIY45264.1 - 0.13 11.9 0.0 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain RabGAP-TBC PF00566.18 KIY45265.1 - 8e-29 100.8 0.0 1.1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.17 KIY45266.1 - 6.7e-09 35.3 0.0 9.4e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY45266.1 - 0.00032 20.2 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY45266.1 - 0.0071 16.2 0.0 0.0095 15.8 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain polyprenyl_synt PF00348.17 KIY45268.1 - 1.8e-94 315.6 0.0 2.2e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF148 PF02520.17 KIY45268.1 - 0.087 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 BAR PF03114.18 KIY45270.1 - 1e-39 136.7 6.3 1.3e-39 136.3 6.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KIY45270.1 - 4.3e-16 58.2 0.1 7.3e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY45270.1 - 3e-14 52.6 0.1 4.6e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY45270.1 - 1.9e-09 37.0 0.0 3.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M3_N PF08439.10 KIY45270.1 - 0.87 9.9 5.6 4.6 7.6 1.5 3.4 3 1 0 3 3 3 0 Oligopeptidase F Atg14 PF10186.9 KIY45271.1 - 9.4e-14 51.2 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 KIY45271.1 - 0.031 11.8 5.4 0.045 11.3 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GBP_C PF02841.14 KIY45271.1 - 0.069 12.6 3.4 0.1 11.9 3.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain VPS38 PF17649.1 KIY45271.1 - 0.2 10.5 2.6 4.3 6.1 0.0 3.2 4 0 0 4 4 4 0 Vacuolar protein sorting 38 Spc7 PF08317.11 KIY45271.1 - 1 8.2 5.9 1.5 7.6 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PUF PF00806.19 KIY45273.1 - 3.7e-56 183.8 7.7 1.4e-07 30.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Glyco_hydro_31 PF01055.26 KIY45274.1 - 4.9e-115 385.2 0.5 6.6e-115 384.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIY45274.1 - 1.6e-15 57.1 0.0 8e-15 54.9 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF4015 PF13200.6 KIY45274.1 - 0.14 11.2 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain Pkinase PF00069.25 KIY45275.1 - 4.9e-22 78.5 0.0 7.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45275.1 - 5.8e-06 25.8 0.0 1.2e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_31 PF01055.26 KIY45276.1 - 3e-19 69.6 0.0 4.9e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIY45276.1 - 1.3e-08 35.1 0.0 3.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like Copper-fist PF00649.18 KIY45277.1 - 2.1e-15 55.9 2.1 2.1e-15 55.9 2.1 2.0 2 1 0 2 2 2 1 Copper fist DNA binding domain UQ_con PF00179.26 KIY45279.1 - 8.7e-25 87.0 0.0 1.1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY45279.1 - 0.0061 16.3 0.0 0.83 9.4 0.0 2.1 1 1 1 2 2 2 2 Prokaryotic E2 family B UFC1 PF08694.11 KIY45279.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Porphobil_deam PF01379.20 KIY45280.1 - 1e-68 230.9 0.0 1.3e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KIY45280.1 - 3.7e-17 62.5 0.2 6.8e-17 61.6 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DnaJ PF00226.31 KIY45281.1 - 7.6e-18 64.4 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.13 KIY45281.1 - 0.29 11.7 2.0 1.8 9.2 0.0 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Zn_clus PF00172.18 KIY45284.1 - 7.2e-07 29.2 6.8 8.6e-07 29.0 6.8 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 KIY45285.1 - 1.3e-12 48.7 0.0 3.2e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY45285.1 - 2e-07 31.3 0.0 5.4e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SBDS PF01172.18 KIY45286.1 - 7.4e-35 118.9 2.3 1.1e-34 118.3 2.3 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 KIY45286.1 - 6e-34 116.5 0.0 1.1e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain Glyco_trans_1_4 PF13692.6 KIY45287.1 - 2.9e-09 37.5 0.0 4.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIY45287.1 - 2.3e-06 28.2 0.1 5.8e-06 26.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KIY45287.1 - 4.4e-05 23.1 0.0 7.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIY45287.1 - 0.00042 20.3 0.4 0.00087 19.3 0.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KIY45287.1 - 0.0016 18.8 0.0 0.0059 17.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Nfu_N PF08712.11 KIY45289.1 - 9.8e-30 102.5 0.0 2.1e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KIY45289.1 - 1e-25 89.6 0.2 1.7e-25 89.0 0.2 1.3 1 0 0 1 1 1 1 NifU-like domain Transp_cyt_pur PF02133.15 KIY45291.1 - 2.1e-05 23.5 1.1 2.5e-05 23.2 1.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PARP PF00644.20 KIY45292.1 - 3.7e-38 131.1 0.0 3.6e-37 127.9 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KIY45292.1 - 1e-17 64.5 0.0 1.5e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KIY45292.1 - 2.1e-13 50.1 0.1 3.8e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 WGR domain Y_phosphatase PF00102.27 KIY45293.1 - 2.6e-52 177.7 0.0 7.8e-52 176.2 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KIY45293.1 - 0.00029 21.3 0.0 0.00054 20.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KIY45293.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-MYND PF01753.18 KIY45294.1 - 5.3e-06 26.4 15.5 1.4e-05 25.0 15.5 1.7 1 0 0 1 1 1 1 MYND finger TetR_C_32 PF09209.11 KIY45294.1 - 0.13 12.3 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MFAP1 PF06991.11 KIY45295.1 - 6.6e-67 225.5 24.8 6.6e-67 225.5 24.8 2.2 4 0 0 4 4 4 1 Microfibril-associated/Pre-mRNA processing TMEM237 PF15383.6 KIY45295.1 - 4.4 6.3 4.3 8.8 5.3 4.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 zf-CCHC PF00098.23 KIY45295.1 - 8.9 6.6 7.2 0.54 10.4 1.3 2.1 2 1 0 2 2 2 0 Zinc knuckle TGT PF01702.18 KIY45296.1 - 8.3e-32 110.7 1.6 1.7e-19 70.2 0.7 3.5 2 2 1 3 3 3 3 Queuine tRNA-ribosyltransferase zf-MYND PF01753.18 KIY45297.1 - 1.1e-08 35.0 11.4 2.8e-08 33.7 11.4 1.7 1 0 0 1 1 1 1 MYND finger VATC PF18716.1 KIY45297.1 - 0.82 9.6 5.1 5.9 6.8 5.1 2.3 1 1 0 1 1 1 0 Vms1-associating treble clef domain F-box-like PF12937.7 KIY45298.1 - 2.2e-06 27.5 0.1 6.7e-06 25.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY45298.1 - 0.002 17.9 0.0 0.0074 16.1 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY45298.1 - 0.045 13.6 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 F-box HSP20 PF00011.21 KIY45299.1 - 6e-22 77.7 0.1 6.9e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY45299.1 - 1e-07 31.4 0.0 1.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DNA_topoisoIV PF00521.20 KIY45300.1 - 4.1e-118 395.0 0.0 9.1e-118 393.8 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KIY45300.1 - 8e-53 178.1 1.3 2.1e-52 176.8 1.3 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KIY45300.1 - 8.5e-29 100.2 1.2 1.9e-28 99.1 1.2 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KIY45300.1 - 7.5e-12 45.8 0.0 2e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KIY45300.1 - 3.9e-08 33.4 0.0 1.5e-07 31.5 0.0 2.1 1 0 0 1 1 1 1 Toprim domain DUF2461 PF09365.10 KIY45300.1 - 0.028 14.4 1.6 0.08 12.9 1.6 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) PhageMin_Tail PF10145.9 KIY45301.1 - 0.085 12.7 0.3 0.085 12.7 0.3 1.6 2 0 0 2 2 2 0 Phage-related minor tail protein Mesothelin PF06060.12 KIY45307.1 - 0.077 11.2 0.0 0.087 11.0 0.0 1.0 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) MFS_1 PF07690.16 KIY45310.1 - 1.7e-21 76.5 22.7 6.2e-20 71.4 24.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY45310.1 - 0.00049 19.5 4.1 0.00049 19.5 4.1 2.7 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Hydantoinase_B PF02538.14 KIY45311.1 - 3.9e-182 606.2 2.1 5.7e-182 605.7 2.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KIY45311.1 - 6.2e-100 334.2 0.2 6.2e-100 334.2 0.2 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIY45311.1 - 3.8e-56 189.6 0.0 2.6e-54 183.6 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MRG PF05712.13 KIY45312.1 - 5e-49 166.3 0.6 1.7e-48 164.6 0.6 1.7 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 KIY45312.1 - 2.5e-11 43.3 0.3 4.3e-11 42.5 0.3 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Retrotran_gag_2 PF14223.6 KIY45313.1 - 0.0046 16.6 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Vta1_C PF18097.1 KIY45313.1 - 0.088 12.5 0.4 0.18 11.5 0.1 1.7 2 0 0 2 2 2 0 Vta1 C-terminal domain Retrotran_gag_2 PF14223.6 KIY45314.1 - 4.4e-08 32.9 0.1 5.7e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIY45314.1 - 0.0031 17.3 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIY45314.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) HTH_3 PF01381.22 KIY45316.1 - 0.071 13.2 0.0 9 6.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix LEM PF03020.15 KIY45316.1 - 0.18 11.4 0.2 1.6 8.4 0.0 2.6 3 0 0 3 3 3 0 LEM domain PALP PF00291.25 KIY45317.1 - 1e-05 25.1 0.0 1.1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KDZ PF18758.1 KIY45319.1 - 5.5e-41 140.6 0.0 8.4e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase FTA4 PF13093.6 KIY45319.1 - 0.46 10.3 5.6 8.7 6.2 0.1 2.1 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 KDZ PF18758.1 KIY45320.1 - 5.6e-25 88.3 0.0 7.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY45320.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases DUF1912 PF08930.10 KIY45321.1 - 0.38 10.9 2.7 1.6 8.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) DUF349 PF03993.12 KIY45321.1 - 0.59 10.5 6.6 0.15 12.3 2.7 2.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Tet_JBP PF12851.7 KIY45322.1 - 0.034 13.5 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily LAL_C2 PF18603.1 KIY45322.1 - 0.049 13.8 0.2 0.11 12.6 0.2 1.6 1 1 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 HALZ PF02183.18 KIY45324.1 - 0.0025 18.0 1.4 1.6 9.0 0.2 2.9 3 0 0 3 3 3 2 Homeobox associated leucine zipper NRBF2 PF08961.10 KIY45324.1 - 0.035 13.7 1.8 1.4 8.5 0.3 2.3 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator HisKA PF00512.25 KIY45324.1 - 0.15 12.1 0.9 0.51 10.4 0.7 2.0 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain TMF_TATA_bd PF12325.8 KIY45324.1 - 0.17 12.1 2.1 34 4.7 0.3 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 KIY45324.1 - 0.24 12.0 4.4 4.4 8.0 0.4 3.6 4 0 0 4 4 4 0 SlyX DivIC PF04977.15 KIY45324.1 - 0.47 10.3 2.5 23 4.8 0.0 3.0 3 0 0 3 3 3 0 Septum formation initiator JIP_LZII PF16471.5 KIY45324.1 - 0.51 10.6 3.9 36 4.6 0.1 3.1 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II CENP-H PF05837.12 KIY45324.1 - 0.6 10.5 5.1 18 5.8 0.0 3.1 3 0 0 3 3 3 0 Centromere protein H (CENP-H) ZapB PF06005.12 KIY45324.1 - 1.4 9.4 6.3 0.75 10.3 0.2 2.5 2 1 0 2 2 2 0 Cell division protein ZapB DUF883 PF05957.13 KIY45324.1 - 6.4 7.4 6.6 33 5.2 0.1 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) HMG_box_2 PF09011.10 KIY45325.1 - 0.0041 17.7 0.0 0.0041 17.7 0.0 1.7 2 0 0 2 2 2 1 HMG-box domain MMPL PF03176.15 KIY45325.1 - 0.046 12.7 0.5 0.054 12.4 0.5 1.1 1 0 0 1 1 1 0 MMPL family HMG_box PF00505.19 KIY45325.1 - 0.057 13.8 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box HTH_32 PF13565.6 KIY45331.1 - 8e-05 23.2 0.0 0.00021 21.8 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KIY45331.1 - 0.0014 18.6 0.1 0.0031 17.5 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KIY45331.1 - 0.0028 17.4 1.3 0.0033 17.2 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KIY45331.1 - 0.017 15.3 0.1 0.041 14.1 0.0 1.7 1 1 0 1 1 1 0 Transposase DDE_3 PF13358.6 KIY45331.1 - 0.086 12.6 0.2 0.31 10.8 0.1 2.0 1 1 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.6 KIY45332.1 - 8e-15 54.9 0.0 9.6e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 KIY45332.1 - 0.014 14.3 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain rve PF00665.26 KIY45332.1 - 0.055 13.7 0.0 0.076 13.2 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain KDZ PF18758.1 KIY45334.1 - 4.6e-24 85.3 6.1 7e-18 65.0 1.2 2.1 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY45334.1 - 0.00018 21.6 0.7 0.00061 19.9 0.0 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CD34_antigen PF06365.12 KIY45336.1 - 0.1 12.2 1.1 1.2 8.7 0.8 2.1 1 1 1 2 2 2 0 CD34/Podocalyxin family GtrA PF04138.14 KIY45337.1 - 1.2 9.4 9.3 0.77 10.0 3.4 2.5 1 1 2 3 3 3 0 GtrA-like protein DUF2752 PF10825.8 KIY45337.1 - 2.5 8.2 8.4 7.5 6.7 0.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2752) BUD22 PF09073.10 KIY45338.1 - 0.017 14.5 14.9 0.025 14.0 14.9 1.1 1 0 0 1 1 1 0 BUD22 Peptidase_C50 PF03568.17 KIY45338.1 - 0.046 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C50 Palm_thioest PF02089.15 KIY45338.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Nop14 PF04147.12 KIY45338.1 - 1.4 7.0 12.0 2.1 6.5 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family Megourin PF17560.2 KIY45339.1 - 0.033 14.4 0.2 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 Aphid Megourins SprA-related PF12118.8 KIY45340.1 - 2.9 7.0 7.8 3.6 6.6 7.8 1.1 1 0 0 1 1 1 0 SprA-related family CBM_26 PF16824.5 KIY45341.1 - 0.011 15.9 0.0 1.2 9.3 0.0 2.1 1 1 1 2 2 2 0 C-terminal carbohydrate-binding module AHJR-like PF18743.1 KIY45341.1 - 0.13 11.8 0.4 2.4 7.7 0.2 2.0 1 1 1 2 2 2 0 REase_AHJR-like Rhodanese PF00581.20 KIY45342.1 - 4.1e-14 53.0 0.0 2.6e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain TUG-UBL1 PF11470.8 KIY45342.1 - 0.021 15.0 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 TUG ubiquitin-like domain V-ATPase_C PF03223.15 KIY45343.1 - 3.6e-128 428.1 3.5 4e-128 427.9 3.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C KH_1 PF00013.29 KIY45344.1 - 4.2e-39 132.2 0.8 1.7e-09 37.3 0.0 6.7 7 0 0 7 7 7 6 KH domain Helicase_C PF00271.31 KIY45345.1 - 3.5e-21 75.6 0.2 8e-21 74.5 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY45345.1 - 5.4e-19 68.8 0.0 1.4e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY45345.1 - 5.2e-18 65.4 0.0 2e-15 57.0 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KIY45345.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase G-patch PF01585.23 KIY45346.1 - 2.5e-12 46.5 0.0 5.7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KIY45346.1 - 6.4e-07 29.5 5.9 1.1e-06 28.7 5.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 KIY45346.1 - 1.4e-06 28.3 1.1 2.9e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 G-patch domain zf-met PF12874.7 KIY45346.1 - 1.6e-05 25.1 1.8 3.2e-05 24.1 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KIY45346.1 - 0.0016 18.7 0.7 0.0026 18.0 0.7 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 KIY45346.1 - 0.0041 17.3 0.7 0.0062 16.7 0.7 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger DUF5059 PF16502.5 KIY45346.1 - 0.043 12.6 0.5 0.052 12.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5059) zf-H2C2_2 PF13465.6 KIY45346.1 - 0.061 13.8 1.6 0.12 12.9 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger double domain DUF4820 PF16091.5 KIY45346.1 - 0.07 12.5 7.2 0.11 11.8 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) zf-DBF PF07535.12 KIY45346.1 - 0.22 11.7 2.7 0.38 10.9 2.7 1.4 1 0 0 1 1 1 0 DBF zinc finger Herpes_capsid PF06112.11 KIY45346.1 - 0.97 9.5 9.6 2 8.5 9.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PXA PF02194.15 KIY45348.1 - 5.7e-43 147.0 0.1 1.4e-42 145.7 0.1 1.7 1 0 0 1 1 1 1 PXA domain Aminotran_4 PF01063.19 KIY45350.1 - 4.5e-29 101.9 0.0 6.1e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Acyltransferase PF01553.21 KIY45351.1 - 1.2e-22 80.0 0.0 1.9e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KIY45351.1 - 4.9e-08 33.0 0.1 1e-05 25.5 0.1 2.4 2 0 0 2 2 2 2 Acyltransferase C-terminus zf-Tim10_DDP PF02953.15 KIY45352.1 - 9.3e-21 73.3 3.0 1e-20 73.1 3.0 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1104 PF06518.11 KIY45354.1 - 0.038 14.4 0.1 0.063 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) AlaDh_PNT_N PF05222.15 KIY45355.1 - 4.7e-29 101.4 0.0 7.1e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KIY45355.1 - 1.4e-05 24.5 0.0 3.3e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TPR_1 PF00515.28 KIY45356.1 - 0.0011 18.7 1.8 0.0034 17.1 0.1 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY45356.1 - 0.0033 17.3 0.0 0.0086 16.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY45356.1 - 0.0042 17.1 0.0 0.023 14.8 0.0 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY45356.1 - 0.023 15.2 0.4 0.097 13.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.25 KIY45357.1 - 1.1e-35 122.8 0.0 1.5e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY45357.1 - 3.7e-26 92.1 0.0 4.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY45357.1 - 3.2e-07 30.4 0.0 4.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIY45357.1 - 5.2e-06 26.5 0.0 1.3e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY45357.1 - 0.014 14.9 0.0 0.036 13.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY45357.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Peptidase_S26 PF10502.9 KIY45358.1 - 5.1e-07 29.5 0.0 0.00018 21.3 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KIY45358.1 - 3.4e-05 23.7 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like PAXNEB PF05625.11 KIY45359.1 - 6.8e-48 163.7 0.0 9.9e-47 159.8 0.0 2.4 1 1 0 1 1 1 1 PAXNEB protein RhoGEF PF00621.20 KIY45360.1 - 1.3e-43 149.3 0.0 2.8e-43 148.3 0.0 1.5 2 0 0 2 2 2 1 RhoGEF domain LRR_8 PF13855.6 KIY45360.1 - 9.2e-09 34.9 4.5 0.0017 18.1 0.2 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIY45360.1 - 8.9e-05 22.8 7.1 0.17 12.3 0.2 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) PH PF00169.29 KIY45360.1 - 0.073 13.6 0.0 0.29 11.7 0.0 1.9 2 0 0 2 2 2 0 PH domain LRR_1 PF00560.33 KIY45360.1 - 0.5 11.1 7.3 19 6.3 0.2 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat TMEM154 PF15102.6 KIY45361.1 - 1.3e-07 31.6 0.8 2.3e-07 30.8 0.8 1.5 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 KIY45361.1 - 4.4e-06 26.9 0.3 7.5e-06 26.1 0.3 1.5 1 0 0 1 1 1 1 Podoplanin BatD PF13584.6 KIY45361.1 - 0.00032 19.7 1.1 0.00038 19.4 0.1 1.5 2 0 0 2 2 2 1 Oxygen tolerance Glycophorin_A PF01102.18 KIY45361.1 - 0.00049 20.3 1.0 0.001 19.3 1.0 1.5 1 0 0 1 1 1 1 Glycophorin A Orf78 PF06024.12 KIY45361.1 - 0.00059 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) Stevor PF17410.2 KIY45361.1 - 0.0011 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF4690 PF15756.5 KIY45361.1 - 0.0023 18.5 0.9 0.0023 18.5 0.9 2.0 2 0 0 2 2 1 1 Small Novel Rich in Cartilage DUF1180 PF06679.12 KIY45361.1 - 0.0041 17.6 1.3 0.0089 16.5 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 KIY45361.1 - 0.0073 17.2 0.0 0.021 15.7 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 KIY45361.1 - 0.0074 16.9 0.3 0.65 10.6 0.0 2.4 1 1 1 2 2 2 1 Oxaloacetate decarboxylase, gamma chain RIFIN PF02009.16 KIY45361.1 - 0.0076 16.2 0.0 0.0096 15.9 0.0 1.1 1 0 0 1 1 1 1 Rifin RCR PF12273.8 KIY45361.1 - 0.011 16.4 0.1 0.033 14.8 0.1 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF5385 PF17359.2 KIY45361.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF4448 PF14610.6 KIY45361.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CcmH PF03918.14 KIY45361.1 - 0.025 13.9 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein UL45 PF05473.12 KIY45361.1 - 0.028 14.1 0.3 0.048 13.3 0.3 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Herpes_gE PF02480.16 KIY45361.1 - 0.032 13.0 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAP10 PF07213.11 KIY45361.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 DAP10 membrane protein DUF5305 PF17231.2 KIY45361.1 - 0.048 13.0 0.2 0.076 12.4 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Amnionless PF14828.6 KIY45361.1 - 0.054 12.3 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4711 PF15829.5 KIY45361.1 - 0.078 12.9 1.9 0.11 12.4 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) DUF2207 PF09972.9 KIY45361.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ECSCR PF15820.5 KIY45361.1 - 0.14 12.0 2.0 0.3 10.9 0.7 2.0 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator Peptidase_M56 PF05569.11 KIY45361.1 - 0.16 11.2 0.1 0.23 10.6 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF5534 PF17686.1 KIY45361.1 - 0.19 12.0 0.6 0.33 11.2 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5534) FixQ PF05545.11 KIY45361.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Gemini_mov PF01708.16 KIY45361.1 - 0.19 11.5 0.3 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Geminivirus putative movement protein MGC-24 PF05283.11 KIY45361.1 - 0.71 10.3 9.9 0.58 10.6 7.5 2.1 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4501 PF14946.6 KIY45361.1 - 3.1 7.8 9.6 0.15 12.1 1.2 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4501) YebO PF13974.6 KIY45361.1 - 7.1 6.8 4.9 2.2 8.4 0.5 2.1 2 0 0 2 2 2 0 YebO-like protein DUF4083 PF13314.6 KIY45361.1 - 8.5 6.4 6.2 1.7 8.6 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) LRR_4 PF12799.7 KIY45362.1 - 0.0029 18.0 0.1 12 6.4 0.0 4.5 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) Hydrolase_4 PF12146.8 KIY45363.1 - 1.1e-07 31.4 0.0 3.2e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY45363.1 - 0.0012 18.6 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold 6PGD PF00393.19 KIY45364.1 - 4.7e-124 413.5 0.0 6.8e-124 412.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KIY45364.1 - 1.8e-49 167.9 0.0 2.7e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIY45364.1 - 0.0036 17.8 0.0 0.007 16.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1825 PF08855.10 KIY45364.1 - 0.13 12.2 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) Oxysterol_BP PF01237.18 KIY45365.1 - 5.3e-108 361.2 0.0 1.5e-107 359.7 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KIY45365.1 - 1.7e-17 63.4 0.0 3.9e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIY45365.1 - 1.2e-05 25.7 0.0 3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 PH domain NPBW PF15180.6 KIY45365.1 - 0.16 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Neuropeptides B and W Alph_Pro_TM PF09608.10 KIY45366.1 - 0.15 11.8 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Dus PF01207.17 KIY45368.1 - 1.2e-49 169.1 0.0 3.9e-49 167.4 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KIY45368.1 - 1.2e-05 25.0 16.9 0.0018 18.0 5.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KIY45368.1 - 0.00015 21.6 8.4 0.09 12.7 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY45368.1 - 0.094 13.4 9.8 0.88 10.3 1.9 2.4 1 1 1 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 KIY45368.1 - 0.25 11.4 13.3 1.6 8.9 0.8 2.5 2 0 0 2 2 2 0 Zinc finger domain Glyco_hydro_3_C PF01915.22 KIY45369.1 - 4e-51 173.9 0.1 6.2e-51 173.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY45369.1 - 4.2e-32 111.8 0.0 1.7e-31 109.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY45369.1 - 4.3e-19 68.4 0.0 8e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.25 KIY45370.1 - 1e-74 251.3 0.0 1.3e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45370.1 - 1.2e-40 139.4 0.0 1.8e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KIY45370.1 - 4.1e-18 66.0 1.0 3.6e-10 40.3 0.0 3.5 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KIY45370.1 - 1.5e-09 37.8 0.1 3.6e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 KIY45370.1 - 3e-06 27.0 0.2 5.4e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KIY45370.1 - 4.6e-05 22.9 0.0 7.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY45370.1 - 7.8e-05 21.8 0.1 0.00012 21.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY45370.1 - 0.0002 20.8 0.5 0.00084 18.7 0.5 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY45370.1 - 0.01 15.7 0.3 0.07 13.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glycos_trans_3N PF02885.17 KIY45370.1 - 0.11 12.3 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain YukC PF10140.9 KIY45370.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Asn_synthase PF00733.21 KIY45371.1 - 1.1e-21 78.0 0.5 2.3e-11 44.0 0.0 2.6 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KIY45371.1 - 2.8e-06 27.3 0.0 1.4e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain tRNA_Me_trans PF03054.16 KIY45371.1 - 0.027 13.3 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase QueC PF06508.13 KIY45371.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KIY45371.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Glucosamine_iso PF01182.20 KIY45373.1 - 9.7e-72 241.5 0.0 1.1e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Lac_bphage_repr PF06543.12 KIY45373.1 - 0.14 12.2 1.3 0.22 11.5 0.3 1.8 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor Ras PF00071.22 KIY45374.1 - 3e-57 192.7 0.2 3.5e-57 192.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY45374.1 - 1.6e-32 112.2 0.0 2.8e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY45374.1 - 1.5e-13 50.6 0.0 1.9e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY45374.1 - 8.3e-08 32.3 0.0 1.7e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY45374.1 - 2e-07 30.6 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY45374.1 - 1.5e-06 27.9 0.1 3.7e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY45374.1 - 3.9e-05 23.6 0.2 0.003 17.5 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KIY45374.1 - 0.00026 20.9 0.2 0.01 15.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 KIY45374.1 - 0.00039 20.1 0.0 0.0013 18.3 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KIY45374.1 - 0.00078 18.8 0.3 0.03 13.6 0.0 2.2 2 1 0 2 2 2 1 Septin PduV-EutP PF10662.9 KIY45374.1 - 0.00099 18.9 0.1 0.16 11.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KIY45374.1 - 0.0043 16.5 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KIY45374.1 - 0.0085 16.4 0.0 0.022 15.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KIY45374.1 - 0.0089 16.4 0.1 0.013 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KIY45374.1 - 0.009 15.8 0.1 0.038 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY45374.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KIY45374.1 - 0.042 13.8 0.3 0.077 12.9 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KIY45374.1 - 0.044 13.7 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase Glyco_hydro_75 PF07335.11 KIY45374.1 - 0.059 13.6 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 AAA_5 PF07728.14 KIY45374.1 - 0.065 13.2 0.1 0.18 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KIY45374.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KIY45374.1 - 0.099 13.2 0.0 1.3 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIY45374.1 - 0.21 12.1 0.7 0.42 11.1 0.7 1.9 1 1 0 1 1 1 0 ABC transporter ATG16 PF08614.11 KIY45375.1 - 3.5e-51 174.3 23.9 3.5e-51 174.3 23.9 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KIY45375.1 - 0.0052 15.7 10.5 0.0052 15.7 10.5 2.5 1 1 1 2 2 2 1 Spc7 kinetochore protein GAS PF13851.6 KIY45375.1 - 0.0057 16.0 14.5 0.0057 16.0 14.5 1.9 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding MAD PF05557.13 KIY45375.1 - 0.031 12.6 21.5 0.026 12.9 20.2 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein YabA PF06156.13 KIY45375.1 - 0.042 14.5 14.9 0.14 12.8 5.9 3.3 1 1 2 3 3 3 0 Initiation control protein YabA RsbRD_N PF14361.6 KIY45375.1 - 0.072 13.8 0.2 0.072 13.8 0.2 2.6 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain zf-C4H2 PF10146.9 KIY45375.1 - 0.13 12.5 9.7 0.021 15.1 5.2 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein Fez1 PF06818.15 KIY45375.1 - 0.15 12.5 19.1 0.064 13.7 11.3 2.2 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 KIY45375.1 - 0.29 11.3 11.8 0.038 14.2 5.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PAP1 PF08601.10 KIY45375.1 - 0.38 10.4 7.7 0.77 9.4 7.7 1.7 1 1 1 2 2 2 0 Transcription factor PAP1 DUF4201 PF13870.6 KIY45375.1 - 0.46 10.2 19.1 0.46 10.2 15.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) USP8_interact PF08941.10 KIY45375.1 - 0.46 10.3 6.9 0.16 11.8 3.5 1.9 2 1 0 2 2 2 0 USP8 interacting FlaC_arch PF05377.11 KIY45375.1 - 2 8.9 11.2 28 5.2 0.5 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KIY45375.1 - 4 6.7 17.5 0.29 10.4 9.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4094 PF13334.6 KIY45375.1 - 4.2 7.9 9.2 2.5 8.6 2.5 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4094) DUF16 PF01519.16 KIY45375.1 - 4.7 7.8 10.2 0.61 10.6 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 XhlA PF10779.9 KIY45375.1 - 4.8 7.5 9.7 9.8 6.5 0.2 2.8 2 0 0 2 2 2 0 Haemolysin XhlA XLF PF09302.11 KIY45375.1 - 5.5 7.1 9.0 1.4e+02 2.5 9.0 2.8 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component FlxA PF14282.6 KIY45375.1 - 7.4 6.6 21.2 0.28 11.2 0.3 3.6 2 1 1 3 3 3 0 FlxA-like protein MPS2 PF17060.5 KIY45375.1 - 7.8 5.7 12.9 29 3.7 0.1 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 Tho2 PF11262.8 KIY45375.1 - 7.8 5.6 7.9 17 4.5 7.9 1.7 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 KASH_CCD PF14662.6 KIY45375.1 - 8.6 6.1 24.3 0.61 9.9 8.1 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH FAM76 PF16046.5 KIY45375.1 - 10 5.4 16.4 1.4e+02 1.6 16.4 2.4 1 1 0 1 1 1 0 FAM76 protein RRM_1 PF00076.22 KIY45376.1 - 2.6e-55 184.1 0.0 2.5e-19 68.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY45376.1 - 3.8e-09 36.2 0.0 4e-05 23.2 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY45376.1 - 2.5e-07 30.5 0.0 9.5e-05 22.2 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.10 KIY45376.1 - 0.00085 19.3 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM_2 PF14605.6 KIY45376.1 - 0.0065 16.4 0.1 2.1 8.4 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KIY45376.1 - 0.0076 16.4 0.0 0.19 11.9 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif PHM7_cyt PF14703.6 KIY45376.1 - 0.02 15.1 0.0 20 5.3 0.0 3.1 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Band_7 PF01145.25 KIY45377.1 - 4.1e-26 92.1 1.4 6.5e-26 91.4 0.9 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KIY45377.1 - 0.0055 15.8 3.1 0.0069 15.5 3.1 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Peptidase_S66 PF02016.15 KIY45377.1 - 0.011 15.9 0.3 0.026 14.6 0.3 1.6 1 1 0 1 1 1 0 LD-carboxypeptidase N-terminal domain Pro-kuma_activ PF09286.11 KIY45379.1 - 1.1e-32 113.2 0.0 2.5e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIY45379.1 - 3.1e-05 23.4 1.4 6.4e-05 22.4 1.4 1.4 1 0 0 1 1 1 1 Subtilase family Aconitase PF00330.20 KIY45380.1 - 1.1e-149 499.3 0.0 1.4e-149 499.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIY45380.1 - 4.2e-32 111.2 0.0 7.2e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MutS_V PF00488.21 KIY45381.1 - 2.1e-69 233.4 0.0 3.4e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIY45381.1 - 2.6e-34 119.1 0.5 7.4e-34 117.6 0.4 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KIY45381.1 - 6.6e-22 77.9 0.0 1.6e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KIY45381.1 - 1.5e-08 35.0 0.0 5.2e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 KIY45381.1 - 5.1e-05 23.0 0.1 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIY45381.1 - 0.054 14.0 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIY45381.1 - 0.096 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KIY45381.1 - 0.13 12.5 0.1 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KIY45382.1 - 5.1e-109 363.9 0.3 7.3e-109 363.4 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KIY45382.1 - 1.4e-06 28.3 0.0 4.1e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY45382.1 - 0.00082 19.0 0.0 0.037 13.6 0.0 2.6 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY45382.1 - 0.0032 17.4 3.3 0.0085 16.0 0.3 2.8 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KIY45382.1 - 0.0032 16.8 0.0 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIY45382.1 - 0.0054 16.8 3.2 2.6 8.1 0.0 3.1 2 1 1 3 3 3 2 Dynamin family Roc PF08477.13 KIY45382.1 - 0.019 15.2 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KIY45382.1 - 0.035 13.5 0.1 0.089 12.1 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KIY45382.1 - 0.047 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KIY45382.1 - 0.05 12.7 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.6 KIY45382.1 - 0.43 11.1 5.8 28 5.1 5.8 2.2 2 0 0 2 2 2 0 AAA domain AA_permease PF00324.21 KIY45383.1 - 9.3e-128 426.8 43.3 1.1e-127 426.5 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY45383.1 - 6.3e-33 114.2 47.2 1e-32 113.5 47.2 1.3 1 1 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 KIY45383.1 - 3.5 8.1 18.3 26 5.3 1.2 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) PDCD9 PF07147.12 KIY45384.1 - 0.015 14.5 0.1 0.016 14.4 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) LRR_4 PF12799.7 KIY45387.1 - 1.3e-07 31.8 9.0 0.0027 18.1 0.3 5.5 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY45387.1 - 0.00031 20.4 6.2 0.012 15.4 0.2 5.2 5 2 2 7 7 7 2 Leucine rich repeat Cortexin PF11057.8 KIY45389.1 - 0.0074 16.1 0.3 0.018 14.9 0.0 1.7 1 1 1 2 2 2 1 Cortexin of kidney DUF846 PF05832.12 KIY45390.1 - 4.3e-54 182.3 8.0 5.5e-54 182.0 8.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Myelin_PLP PF01275.19 KIY45390.1 - 0.063 13.1 1.3 0.17 11.8 1.3 1.6 1 1 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) DUF2207 PF09972.9 KIY45390.1 - 1.4 7.6 3.7 2.9 6.6 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) GST_N_3 PF13417.6 KIY45391.1 - 1.4e-07 31.8 0.0 2.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY45391.1 - 0.0074 16.6 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Asp PF00026.23 KIY45392.1 - 2.1e-73 247.5 8.0 2.6e-73 247.2 8.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY45392.1 - 3.4e-10 40.5 3.5 6.1e-08 33.1 3.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY45392.1 - 0.0017 18.9 0.9 0.25 12.0 0.2 3.4 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KIY45392.1 - 0.014 15.1 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal HhH-GPD PF00730.25 KIY45393.1 - 3.2e-08 34.0 0.0 5.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIY45393.1 - 0.015 15.2 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Trypan_glycop PF00913.19 KIY45393.1 - 0.037 13.3 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DSPc PF00782.20 KIY45394.1 - 1.6e-17 63.6 0.0 9.9e-11 41.6 0.0 3.0 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIY45394.1 - 0.027 14.8 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIY45394.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Tetraspanin PF00335.20 KIY45395.1 - 0.028 14.1 15.5 0.077 12.7 15.6 1.7 1 1 0 1 1 1 0 Tetraspanin family DUF4149 PF13664.6 KIY45395.1 - 0.18 12.1 3.3 11 6.5 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DUF4191 PF13829.6 KIY45395.1 - 0.28 10.5 0.7 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF3040 PF11239.8 KIY45395.1 - 2.3 8.6 4.8 0.73 10.1 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) Gram_pos_anchor PF00746.21 KIY45395.1 - 3.3 7.7 4.8 12 6.0 0.0 3.1 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Glyco_transf_25 PF01755.17 KIY45396.1 - 4.1e-11 43.1 0.0 2.7e-10 40.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) FAD_binding_6 PF00970.24 KIY45397.1 - 8.2e-33 112.7 0.0 1.5e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KIY45397.1 - 2.5e-30 105.3 0.0 3.7e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_9 PF08021.11 KIY45397.1 - 0.00076 19.7 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.12 KIY45397.1 - 0.0011 19.1 0.0 0.01 16.0 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain CAP PF00188.26 KIY45399.1 - 8.1e-20 71.9 0.8 2.4e-19 70.4 0.8 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family HMG_box PF00505.19 KIY45400.1 - 4.1e-08 33.5 0.0 7.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Pkinase PF00069.25 KIY45401.1 - 1.7e-68 230.9 0.0 2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45401.1 - 1.5e-28 99.8 0.0 1.9e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY45401.1 - 9.9e-07 28.3 0.2 0.00031 20.1 0.0 2.2 1 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KIY45401.1 - 0.00034 20.3 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KIY45401.1 - 0.14 11.1 0.1 0.28 10.1 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain AMP-binding PF00501.28 KIY45402.1 - 3.5e-68 230.1 0.1 4.1e-68 229.9 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY45402.1 - 4.5e-20 72.4 0.1 1.8e-19 70.5 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TTL PF03133.15 KIY45403.1 - 1.3e-47 162.4 0.0 1.6e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family MMM1 PF10296.9 KIY45404.1 - 4.1e-32 111.6 0.6 4.3e-16 58.9 0.0 3.0 1 1 2 3 3 3 3 Maintenance of mitochondrial morphology protein 1 RNA_pol_Rpb8 PF03870.15 KIY45405.1 - 2.8e-47 160.4 0.4 3.2e-47 160.2 0.4 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Sec7 PF01369.20 KIY45407.1 - 1e-29 103.5 0.6 1.8e-29 102.7 0.6 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KIY45407.1 - 7.8e-14 52.1 0.0 2e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIY45407.1 - 5.7e-10 39.7 0.0 1.2e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 PH domain Pescadillo_N PF06732.11 KIY45408.1 - 1.3e-122 408.6 0.0 1.3e-122 408.6 0.0 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KIY45408.1 - 2.7e-08 34.1 0.0 6.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KIY45408.1 - 0.00023 21.4 0.2 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KIY45408.1 - 0.00056 20.2 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DWNN PF08783.11 KIY45408.1 - 4.9 7.5 6.2 0.81 10.0 0.1 2.7 4 0 0 4 4 4 0 DWNN domain LSM PF01423.22 KIY45409.1 - 3e-06 26.8 0.1 5.8e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 KIY45409.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Hfq protein RdRP PF05183.12 KIY45410.1 - 2.6e-173 577.8 0.0 3.5e-173 577.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase GFO_IDH_MocA PF01408.22 KIY45411.1 - 1.6e-10 41.9 0.0 7.5e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIY45411.1 - 0.011 15.8 0.0 0.032 14.2 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Cyclin_N PF00134.23 KIY45413.1 - 7.8e-39 132.3 1.0 8e-38 129.1 0.3 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY45413.1 - 4e-12 46.3 0.3 9.5e-12 45.1 0.3 1.7 1 1 0 1 1 1 1 Cyclin, C-terminal domain DUF4364 PF14277.6 KIY45413.1 - 0.044 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) HalOD1 PF18545.1 KIY45414.1 - 0.19 12.0 0.9 9.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Halobacterial output domain 1 GET2 PF08690.10 KIY45414.1 - 2.4 7.8 9.9 0.11 12.1 1.3 2.7 3 0 0 3 3 3 0 GET complex subunit GET2 WD40 PF00400.32 KIY45415.1 - 4.1e-15 55.9 12.1 6.2e-06 26.8 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY45415.1 - 4.5e-11 42.9 1.8 0.0013 19.0 0.1 3.7 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY45415.1 - 0.0051 15.8 0.8 0.27 10.2 0.1 2.8 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5136 PF17199.4 KIY45416.1 - 0.06 13.1 2.7 0.076 12.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5136) ubiquitin PF00240.23 KIY45417.1 - 4.5e-137 446.0 18.7 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KIY45417.1 - 2.8e-63 209.7 20.7 3e-15 55.8 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIY45417.1 - 3.5e-23 81.8 9.2 0.00045 20.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KIY45417.1 - 4e-16 58.7 3.0 0.033 14.1 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KIY45417.1 - 1.5e-14 54.2 7.5 0.044 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY45417.1 - 1.6e-14 54.0 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KIY45417.1 - 5e-13 49.5 1.1 0.36 11.4 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KIY45417.1 - 6e-10 39.2 0.5 1.1 9.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KIY45417.1 - 4.3e-07 29.9 24.6 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KIY45417.1 - 5.1e-07 29.3 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KIY45417.1 - 3.9e-06 26.9 2.8 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 KIY45417.1 - 4.4e-06 27.4 0.1 30 5.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 KIY45417.1 - 5.6e-06 26.7 0.0 30 5.1 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KIY45417.1 - 1e-05 25.3 3.8 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 KIY45417.1 - 1.1e-05 25.4 0.1 29 4.9 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 KIY45417.1 - 5.6e-05 23.2 3.2 6.9 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KIY45417.1 - 0.00033 20.2 0.1 21 4.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KIY45417.1 - 0.00036 21.1 0.9 73 4.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.14 KIY45417.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KIY45417.1 - 0.007 16.5 0.0 91 3.3 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KIY45417.1 - 0.011 15.9 5.3 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KIY45417.1 - 0.041 13.7 9.2 43 4.1 0.1 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 KIY45417.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 KIY45417.1 - 0.44 11.1 9.2 46 4.6 1.3 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KIY45417.1 - 1.1 9.5 4.6 2.4e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KIY45417.1 - 1.2 9.0 8.5 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KIY45417.1 - 1.2 9.3 9.9 1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein CSN8_PSD8_EIF3K PF10075.9 KIY45418.1 - 4.5e-21 75.3 0.0 6.5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family WD40 PF00400.32 KIY45419.1 - 1.4e-54 180.8 15.5 2.1e-08 34.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY45419.1 - 3.3e-18 65.8 0.9 0.0026 18.0 0.0 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY45419.1 - 1.5e-11 44.5 0.2 2.4e-05 24.3 0.1 3.6 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIY45419.1 - 2.1e-08 33.3 3.4 0.00033 19.5 0.0 4.6 1 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIY45419.1 - 2.1e-07 30.2 1.7 0.046 12.7 0.0 4.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIY45419.1 - 0.00013 21.4 0.3 0.0047 16.3 0.0 2.9 2 1 0 3 3 3 1 WD40-like domain PD40 PF07676.12 KIY45419.1 - 0.0058 16.5 0.7 1.9 8.6 0.1 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat WAC_Acf1_DNA_bd PF10537.9 KIY45420.1 - 2.9e-34 117.6 0.5 6.6e-34 116.5 0.5 1.6 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KIY45420.1 - 2.8e-29 101.5 0.1 2.8e-29 101.5 0.1 3.0 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KIY45420.1 - 1.3e-13 51.0 1.0 2.9e-13 49.9 0.3 2.0 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 KIY45420.1 - 3.3e-10 39.2 0.0 7.7e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 RNF220 PF15926.5 KIY45420.1 - 0.02 14.5 0.8 0.02 14.5 0.8 2.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 DUF4407 PF14362.6 KIY45420.1 - 0.032 13.6 10.3 0.12 11.7 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Aa_trans PF01490.18 KIY45421.1 - 6.4e-56 189.8 15.8 7.9e-56 189.5 15.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ntox22 PF15527.6 KIY45421.1 - 0.0019 18.3 1.0 0.0044 17.1 1.0 1.6 1 0 0 1 1 1 1 Bacterial toxin 22 Fcf1 PF04900.12 KIY45422.1 - 4.1e-33 113.7 0.0 6e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Fcf1 DUF2012 PF09430.10 KIY45423.1 - 1e-21 77.3 0.0 1.5e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 KIY45423.1 - 0.0021 17.8 0.1 0.0062 16.3 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KIY45423.1 - 0.021 15.1 0.1 0.046 14.0 0.0 1.6 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KIY45423.1 - 0.048 13.7 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 CarboxypepD_reg-like domain DUF2457 PF10446.9 KIY45424.1 - 7.2 5.6 19.8 0.65 9.1 5.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) NIT PF08376.10 KIY45426.1 - 0.073 13.5 0.6 0.16 12.4 0.6 1.5 1 0 0 1 1 1 0 Nitrate and nitrite sensing DnaJ PF00226.31 KIY45427.1 - 3.7e-21 75.0 3.2 6.1e-21 74.3 3.2 1.4 1 0 0 1 1 1 1 DnaJ domain Rick_17kDa_Anti PF05433.15 KIY45427.1 - 2.5 8.0 14.4 7 6.6 0.0 3.4 3 0 0 3 3 3 0 Glycine zipper 2TM domain Sin_N PF04801.13 KIY45428.1 - 3.8e-28 98.9 0.0 5.2e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Myb_Cef PF11831.8 KIY45429.1 - 4.8e-56 190.0 4.0 4.8e-56 190.0 4.0 4.2 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KIY45429.1 - 3.3e-22 78.4 6.0 9.2e-11 41.8 1.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY45429.1 - 1.8e-19 69.7 6.9 1.2e-12 47.8 3.1 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF3580 PF12117.8 KIY45429.1 - 0.012 15.9 0.2 0.028 14.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Rap1_C PF11626.8 KIY45429.1 - 1.2 9.2 5.3 2.6 8.2 0.1 3.7 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain NMT1 PF09084.11 KIY45430.1 - 0.12 12.3 1.7 2.9 7.8 0.3 2.2 2 0 0 2 2 2 0 NMT1/THI5 like EVC2_like PF12297.8 KIY45430.1 - 0.18 10.5 0.4 2.7 6.6 0.1 2.0 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein BacteriocIIc_cy PF12173.8 KIY45430.1 - 0.25 11.6 4.4 0.45 10.8 0.4 2.9 2 1 1 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like DUF3533 PF12051.8 KIY45431.1 - 1.2e-70 238.4 22.5 4.4e-36 124.6 1.0 2.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3533) DUF3842 PF12953.7 KIY45431.1 - 0.11 12.9 1.4 0.47 10.8 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) DUF3235 PF11574.8 KIY45432.1 - 0.14 13.0 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Cullin PF00888.22 KIY45433.1 - 3.8e-127 425.5 1.9 5.2e-127 425.1 1.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIY45433.1 - 5.4e-22 77.6 2.7 1.6e-21 76.1 2.7 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain EcoEI_R_C PF08463.10 KIY45433.1 - 0.016 15.3 0.2 2.6 8.1 0.2 2.7 1 1 0 1 1 1 0 EcoEI R protein C-terminal DUF1803 PF08820.10 KIY45433.1 - 0.15 12.1 1.6 0.26 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) RRM_1 PF00076.22 KIY45434.1 - 1.8e-55 184.7 0.0 3.9e-15 55.4 0.0 6.5 5 1 1 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY45434.1 - 1.4e-08 34.7 0.0 0.037 14.2 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif PHM7_cyt PF14703.6 KIY45434.1 - 0.00034 20.9 1.7 16 5.6 0.0 5.9 4 3 1 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KIY45434.1 - 0.0013 18.5 0.0 2.6 7.8 0.0 3.3 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain ARID PF01388.21 KIY45435.1 - 3e-10 40.6 0.0 1.4e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KIY45435.1 - 0.00027 20.3 0.5 0.014 14.7 0.1 2.9 3 0 0 3 3 3 1 SWI/SNF-like complex subunit BAF250/Osa DUF1764 PF08576.10 KIY45436.1 - 1.3e-22 80.6 7.5 8.5e-21 74.7 7.5 2.1 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) FbpA PF05833.11 KIY45436.1 - 0.026 13.3 0.1 0.03 13.1 0.1 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1295 PF06966.12 KIY45437.1 - 1.3e-34 119.8 8.3 1.5e-33 116.3 3.9 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1295) ICMT PF04140.14 KIY45437.1 - 0.029 14.8 0.0 0.16 12.4 0.0 2.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Cyd_oper_YbgE PF09600.10 KIY45437.1 - 0.039 14.3 0.2 0.039 14.3 0.2 2.8 4 0 0 4 4 4 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Ribonuc_L-PSP PF01042.21 KIY45438.1 - 1.5e-42 144.5 0.1 1.6e-42 144.3 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ThiG PF05690.14 KIY45438.1 - 0.035 13.4 0.3 0.054 12.8 0.3 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Arrestin_C PF02752.22 KIY45439.1 - 0.0013 19.1 0.3 0.018 15.5 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain SNF2_N PF00176.23 KIY45440.1 - 9.1e-57 192.3 0.0 6.9e-49 166.4 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY45440.1 - 1.5e-14 54.3 0.0 6.9e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY45440.1 - 5.8e-07 29.7 0.5 1.4e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY45440.1 - 3.4e-05 23.7 0.0 9.2e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 KIY45440.1 - 0.00042 20.1 4.1 0.00042 20.1 4.1 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY45440.1 - 0.0011 19.3 1.7 0.0027 17.9 1.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIY45440.1 - 0.0017 18.6 4.2 0.0017 18.6 4.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY45440.1 - 0.0029 17.4 1.5 0.0029 17.4 1.5 3.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KIY45440.1 - 0.018 14.8 1.2 0.049 13.5 1.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KIY45440.1 - 0.04 14.0 0.5 0.04 14.0 0.5 3.0 3 1 0 3 3 2 0 RING-type zinc-finger DEAD_2 PF06733.15 KIY45440.1 - 1.5 8.4 6.9 0.29 10.7 0.1 2.9 3 1 0 3 3 3 0 DEAD_2 Ras PF00071.22 KIY45441.1 - 5.6e-55 185.4 0.0 9.8e-55 184.6 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KIY45441.1 - 5.9e-34 116.9 0.0 8.5e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY45441.1 - 2.5e-14 53.1 0.0 7.9e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY45441.1 - 3.4e-07 29.9 0.0 3.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY45441.1 - 2.1e-05 24.2 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY45441.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY45441.1 - 0.0026 18.1 0.4 0.0059 17.0 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain MRI PF15325.6 KIY45441.1 - 0.46 11.6 4.3 0.32 12.1 2.1 1.9 2 0 0 2 2 2 0 Modulator of retrovirus infection BRCT_2 PF16589.5 KIY45442.1 - 4.3e-14 52.7 0.0 1.4e-07 31.8 0.0 2.4 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KIY45442.1 - 4.9e-10 39.4 1.7 1.5e-09 37.9 1.7 1.8 1 1 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 KIY45442.1 - 0.79 10.3 3.9 3.7 8.2 3.9 2.0 1 1 0 1 1 1 0 Rap1, DNA-binding GYF PF02213.16 KIY45443.1 - 3.9e-16 58.4 0.0 8.3e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KIY45443.1 - 0.026 14.3 0.1 0.071 12.9 0.1 1.8 2 0 0 2 2 2 0 GYF domain 2 LRRFIP PF09738.9 KIY45443.1 - 0.093 12.2 1.8 0.17 11.3 1.8 1.3 1 0 0 1 1 1 0 LRRFIP family LIM PF00412.22 KIY45445.1 - 3.1e-13 49.7 21.9 9.1e-06 25.8 1.8 5.8 5 1 0 5 5 5 4 LIM domain DUF1720 PF08226.11 KIY45445.1 - 1.4 9.4 11.4 14 6.1 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1720) AAA_18 PF13238.6 KIY45446.1 - 4.4e-30 104.9 0.0 6e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIY45446.1 - 3.9e-05 24.1 0.0 0.0001 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY45446.1 - 4.5e-05 23.6 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIY45446.1 - 5.3e-05 23.7 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KIY45446.1 - 0.00026 21.3 0.0 0.00068 19.9 0.0 1.8 2 1 1 3 3 3 1 AAA domain ADK PF00406.22 KIY45446.1 - 0.0023 18.1 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_22 PF13401.6 KIY45446.1 - 0.0036 17.6 0.0 0.0093 16.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KIY45446.1 - 0.0061 16.5 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain KTI12 PF08433.10 KIY45446.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RuvB_N PF05496.12 KIY45446.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 KIY45446.1 - 0.016 15.0 0.3 2 8.3 0.0 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 KIY45446.1 - 0.016 15.1 1.2 0.34 10.8 0.2 2.1 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 KIY45446.1 - 0.017 15.6 0.0 0.025 15.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KIY45446.1 - 0.026 14.9 0.4 0.049 14.0 0.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KIY45446.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KIY45446.1 - 0.046 13.8 0.1 0.14 12.3 0.1 1.8 1 1 0 1 1 1 0 Shikimate kinase DUF2075 PF09848.9 KIY45446.1 - 0.059 12.6 0.1 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KIY45446.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KIY45446.1 - 0.087 11.8 1.0 0.15 11.0 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KIY45446.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIY45446.1 - 0.091 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 KIY45446.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KIY45446.1 - 0.15 11.7 0.2 0.28 10.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIY45446.1 - 0.2 10.9 0.1 0.77 9.1 0.1 1.9 2 1 1 3 3 3 0 KaiC Med9 PF07544.13 KIY45447.1 - 1.1e-05 25.4 0.8 1.5e-05 25.0 0.8 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF883 PF05957.13 KIY45447.1 - 0.0025 18.4 2.6 0.05 14.2 0.2 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) SIL1 PF16782.5 KIY45447.1 - 0.027 13.7 0.2 0.032 13.5 0.2 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 Syntaxin-5_N PF11416.8 KIY45447.1 - 0.036 13.3 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 0 Syntaxin-5 N-terminal, Sly1p-binding domain Taeniidae_ag PF05596.11 KIY45447.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Taeniidae antigen Fer4_12 PF13353.6 KIY45447.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain RNA_polI_A14 PF08203.11 KIY45447.1 - 0.3 11.8 2.7 4.1 8.2 0.5 2.1 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Cyclin_C_2 PF16899.5 KIY45448.1 - 9.1e-19 67.8 0.1 1.7e-16 60.5 0.0 2.6 2 1 1 3 3 3 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KIY45448.1 - 7e-09 35.5 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KIY45448.1 - 0.001 19.0 0.0 0.026 14.6 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 KIY45448.1 - 0.024 14.7 0.2 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain LexA_DNA_bind PF01726.16 KIY45448.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 LexA DNA binding domain FMN_dh PF01070.18 KIY45449.1 - 9.5e-96 320.8 0.0 1.1e-95 320.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIY45449.1 - 8e-21 74.0 0.0 1.6e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KIY45449.1 - 0.0002 20.5 0.5 0.0012 17.9 0.3 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KIY45449.1 - 0.00076 18.7 0.0 0.0022 17.2 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 KIY45449.1 - 0.0063 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KIY45449.1 - 0.048 13.0 0.3 7.5 5.8 0.0 2.2 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG MeMO_Hyd_G PF02964.16 KIY45449.1 - 0.18 11.8 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain EzrA PF06160.12 KIY45450.1 - 0.00017 19.9 0.8 0.00025 19.4 0.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.11 KIY45450.1 - 0.00035 19.6 2.4 0.0006 18.8 2.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 KIY45450.1 - 0.00096 19.2 0.9 0.0023 18.0 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) STAT_alpha PF01017.20 KIY45450.1 - 0.0018 18.2 1.8 0.0042 17.0 1.0 2.0 1 1 1 2 2 2 1 STAT protein, all-alpha domain Tup_N PF08581.10 KIY45450.1 - 0.0025 18.1 6.0 0.35 11.2 0.3 3.1 1 1 1 2 2 2 1 Tup N-terminal PRKG1_interact PF15898.5 KIY45450.1 - 0.0034 18.2 4.5 0.1 13.5 3.3 3.0 1 1 1 2 2 2 1 cGMP-dependent protein kinase interacting domain Filament PF00038.21 KIY45450.1 - 0.0053 16.4 1.8 0.01 15.4 1.8 1.4 1 0 0 1 1 1 1 Intermediate filament protein Baculo_PEP_C PF04513.12 KIY45450.1 - 0.0056 16.7 0.4 0.011 15.8 0.4 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 KIY45450.1 - 0.0059 16.8 1.8 0.15 12.3 1.5 2.5 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 KIY45450.1 - 0.01 16.3 3.1 0.81 10.2 1.7 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 KIY45450.1 - 0.027 13.9 3.3 0.045 13.2 3.3 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal LUC7 PF03194.15 KIY45450.1 - 0.043 13.5 0.1 0.095 12.4 0.1 1.5 1 0 0 1 1 1 0 LUC7 N_terminus DUF4349 PF14257.6 KIY45450.1 - 0.044 13.2 6.9 0.099 12.1 6.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) V_ATPase_I PF01496.19 KIY45450.1 - 0.067 11.1 0.1 0.093 10.6 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.7 KIY45450.1 - 0.069 13.3 3.7 0.2 11.8 3.7 1.8 1 0 0 1 1 1 0 Tropomyosin like CENP-F_leu_zip PF10473.9 KIY45450.1 - 0.087 12.8 7.8 0.42 10.6 6.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 KIY45450.1 - 0.1 11.9 6.8 0.17 11.2 5.0 1.8 1 1 1 2 2 2 0 Tropomyosin APG6_N PF17675.1 KIY45450.1 - 0.11 13.0 3.3 0.36 11.4 3.3 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region Prominin PF05478.11 KIY45450.1 - 0.16 9.9 0.9 0.23 9.4 0.9 1.1 1 0 0 1 1 1 0 Prominin Sec34 PF04136.15 KIY45450.1 - 0.19 11.6 0.9 0.35 10.8 0.9 1.4 1 0 0 1 1 1 0 Sec34-like family Actin_micro PF17003.5 KIY45450.1 - 0.19 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Putative actin-like family Atg14 PF10186.9 KIY45450.1 - 0.22 10.6 1.7 0.77 8.8 1.9 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CdvA PF18822.1 KIY45450.1 - 0.27 11.1 2.7 1.9 8.3 1.6 2.7 3 1 1 4 4 3 0 CdvA-like coiled-coil domain BLOC1_2 PF10046.9 KIY45450.1 - 0.31 11.4 3.8 2.6 8.4 3.0 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 KIY45450.1 - 0.31 11.3 3.3 0.31 11.4 1.3 1.9 2 0 0 2 2 1 0 Uncharacterized conserved protein Sec8_exocyst PF04048.14 KIY45450.1 - 0.34 10.8 1.5 0.63 9.9 1.5 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain CHASE3 PF05227.13 KIY45450.1 - 0.36 10.7 5.6 0.62 10.0 4.3 2.0 1 1 1 2 2 2 0 CHASE3 domain FlaC_arch PF05377.11 KIY45450.1 - 0.38 11.2 3.9 1.9 8.9 1.1 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cob_adeno_trans PF01923.18 KIY45450.1 - 0.38 10.9 2.7 3.7 7.7 0.6 2.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase MutS_III PF05192.18 KIY45450.1 - 0.65 10.2 5.8 3 8.0 3.3 2.2 1 1 1 2 2 2 0 MutS domain III Snapin_Pallidin PF14712.6 KIY45450.1 - 0.65 10.5 4.6 2.2 8.7 4.6 2.0 1 1 0 1 1 1 0 Snapin/Pallidin Med9 PF07544.13 KIY45450.1 - 0.7 10.0 3.8 0.77 9.9 0.7 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 KIY45450.1 - 0.81 9.0 5.3 1.4 8.2 4.4 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CLZ PF16526.5 KIY45450.1 - 1.9 8.9 9.4 4.3 7.8 0.2 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MscS_porin PF12795.7 KIY45450.1 - 1.9 8.0 11.5 0.027 14.0 3.0 2.3 3 0 0 3 3 1 0 Mechanosensitive ion channel porin domain DUF2730 PF10805.8 KIY45450.1 - 1.9 8.6 3.8 2.1 8.5 2.1 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF2730) Syntaxin-6_N PF09177.11 KIY45450.1 - 1.9 9.1 4.4 10 6.8 4.4 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Taxilin PF09728.9 KIY45450.1 - 2.6 7.1 7.3 0.11 11.6 1.2 1.8 2 0 0 2 2 2 0 Myosin-like coiled-coil protein CCDC-167 PF15188.6 KIY45450.1 - 4.3 7.8 6.5 8.8 6.8 1.8 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Pkinase PF00069.25 KIY45451.1 - 8.5e-65 218.7 0.0 1e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45451.1 - 1.7e-26 93.0 0.0 3.9e-26 91.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY45451.1 - 3.2e-05 23.4 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY45451.1 - 0.014 14.4 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KIY45451.1 - 0.019 14.4 0.2 0.03 13.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY45451.1 - 0.029 14.3 0.4 0.068 13.1 0.5 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY45451.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Spa1_C PF18218.1 KIY45451.1 - 0.15 12.5 0.0 0.67 10.4 0.0 2.0 2 0 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain DKCLD PF08068.12 KIY45452.1 - 3.8e-33 113.3 0.1 4.1e-32 110.0 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KIY45452.1 - 8.3e-24 84.7 1.1 1.9e-20 73.8 0.1 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KIY45452.1 - 2.6e-23 81.9 0.8 5.7e-23 80.8 0.8 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KIY45452.1 - 1.3e-21 76.3 0.4 3.1e-21 75.1 0.4 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KIY45452.1 - 0.001 19.3 0.0 0.004 17.4 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain RNA_polI_A34 PF08208.11 KIY45452.1 - 2.4 8.2 16.0 4 7.5 16.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 KIY45452.1 - 7.4 4.7 9.7 11 4.2 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L22e PF01776.17 KIY45453.1 - 1.8e-45 153.8 0.3 2.1e-45 153.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family SET PF00856.28 KIY45454.1 - 1.5e-09 38.4 1.7 1.6e-09 38.4 0.1 1.9 2 1 0 2 2 2 1 SET domain HA2 PF04408.23 KIY45455.1 - 4.4e-17 62.3 0.0 1.6e-16 60.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY45455.1 - 1.4e-14 54.4 0.0 3.8e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIY45455.1 - 4.6e-09 36.5 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KIY45455.1 - 6.1e-08 32.6 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY45455.1 - 2.3e-06 27.9 0.1 5.7e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIY45455.1 - 0.0072 15.4 0.0 0.042 12.9 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 KIY45455.1 - 0.013 16.0 0.0 0.049 14.1 0.0 2.0 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KIY45455.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KIY45455.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Lyase_1 PF00206.20 KIY45456.1 - 1.2e-120 402.6 0.0 1.6e-120 402.3 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KIY45456.1 - 2.3e-19 69.6 0.0 5.3e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus B3_4 PF03483.17 KIY45456.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 B3/4 domain G-alpha PF00503.20 KIY45456.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SNF2_N PF00176.23 KIY45457.1 - 1.5e-61 208.1 0.9 2.8e-61 207.2 0.9 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KIY45457.1 - 3.4e-42 144.0 19.0 3.4e-42 144.0 19.0 3.0 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 KIY45457.1 - 1.8e-15 57.2 0.0 6e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KIY45457.1 - 2.6e-05 23.6 0.0 0.00014 21.2 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF4035 PF13227.6 KIY45457.1 - 0.11 12.2 0.5 0.31 10.8 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Glyco_hydro_15 PF00723.21 KIY45458.1 - 1.8e-25 89.7 0.0 2.6e-13 49.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 PEX11 PF05648.14 KIY45459.1 - 1.2e-50 172.1 1.1 1.3e-50 171.9 1.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Cmc1 PF08583.10 KIY45460.1 - 1.6e-11 44.0 3.3 2e-11 43.7 3.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like LIAS_N PF16881.5 KIY45461.1 - 6.8e-23 81.2 0.0 1.8e-22 79.8 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KIY45461.1 - 2.1e-13 51.0 0.0 5e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Ribosomal_S28e PF01200.18 KIY45462.1 - 2.5e-31 107.4 1.0 2.8e-31 107.3 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Glyco_transf_8 PF01501.20 KIY45463.1 - 2.3e-16 60.2 0.0 4.2e-16 59.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KIY45463.1 - 0.0041 16.5 0.0 0.01 15.2 0.0 1.7 2 0 0 2 2 2 1 Mannosyltransferase putative Peripla_BP_2 PF01497.18 KIY45463.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Peptidase_M22 PF00814.25 KIY45464.1 - 2.7e-81 273.3 0.0 3.1e-81 273.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KIY45464.1 - 0.01 15.5 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus DivIC PF04977.15 KIY45465.1 - 0.00064 19.4 23.6 0.0023 17.7 2.5 3.8 3 0 0 3 3 3 2 Septum formation initiator Pox_A_type_inc PF04508.12 KIY45465.1 - 0.13 12.2 3.8 1.6 8.7 0.3 3.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Totivirus_coat PF05518.11 KIY45465.1 - 0.19 9.7 6.7 0.33 9.0 6.7 1.3 1 0 0 1 1 1 0 Totivirus coat protein DUF1192 PF06698.11 KIY45465.1 - 0.28 11.3 5.9 0.87 9.7 2.1 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1192) TraF_2 PF13729.6 KIY45465.1 - 0.33 10.3 1.6 0.68 9.2 0.3 1.9 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein SHE3 PF17078.5 KIY45465.1 - 0.34 10.6 18.7 0.098 12.4 9.3 2.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 GAS PF13851.6 KIY45465.1 - 0.61 9.4 28.8 0.05 12.9 17.6 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 KIY45465.1 - 0.95 10.1 14.3 0.099 13.2 5.7 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal BRE1 PF08647.11 KIY45465.1 - 1.2 9.2 24.4 0.082 13.0 14.8 3.5 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase FapA PF03961.13 KIY45465.1 - 2.2 6.8 6.5 3.5 6.1 6.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A ERM PF00769.19 KIY45465.1 - 2.9 7.6 45.7 0.044 13.6 27.2 2.7 2 1 0 3 3 2 0 Ezrin/radixin/moesin family FH2 PF02181.23 KIY45465.1 - 4.3 6.4 14.7 0.22 10.6 6.0 2.5 2 1 1 3 3 3 0 Formin Homology 2 Domain 2-oxoacid_dh PF00198.23 KIY45466.1 - 4.3e-79 265.3 0.0 5.4e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIY45466.1 - 7.1e-20 70.6 1.0 1.6e-19 69.5 0.5 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KIY45466.1 - 3.2e-13 49.8 0.2 3.2e-13 49.8 0.2 2.1 2 0 0 2 2 2 1 e3 binding domain DEC-1_N PF04625.13 KIY45466.1 - 0.0043 16.1 11.1 0.042 12.9 0.7 2.2 2 0 0 2 2 2 2 DEC-1 protein, N-terminal region EXOSC1 PF10447.9 KIY45467.1 - 2.3e-18 66.8 1.3 2.6e-13 50.5 0.3 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KIY45467.1 - 0.00085 19.1 0.1 0.0022 17.8 0.1 1.8 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region NUDE_C PF04880.13 KIY45468.1 - 6.3e-07 30.0 3.6 6.3e-07 30.0 3.6 3.0 1 1 2 3 3 3 1 NUDE protein, C-terminal conserved region PRKG1_interact PF15898.5 KIY45468.1 - 0.00074 20.4 22.3 0.21 12.5 5.1 3.2 1 1 2 3 3 3 2 cGMP-dependent protein kinase interacting domain DUF2353 PF09789.9 KIY45468.1 - 0.0011 18.4 11.2 0.0011 18.4 11.2 2.3 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) Macoilin PF09726.9 KIY45468.1 - 0.0041 15.8 15.8 0.005 15.5 15.8 1.1 1 0 0 1 1 1 1 Macoilin family FXMRP1_C_core PF12235.8 KIY45468.1 - 0.0066 17.1 2.5 0.0066 17.1 2.5 2.6 2 1 0 2 2 2 1 Fragile X-related 1 protein core C terminal DegS PF05384.11 KIY45468.1 - 0.0071 15.9 8.2 0.0071 15.9 8.2 2.4 1 1 1 2 2 2 1 Sensor protein DegS ZapB PF06005.12 KIY45468.1 - 0.008 16.6 4.5 0.008 16.6 4.5 3.4 2 2 1 3 3 3 1 Cell division protein ZapB GAS PF13851.6 KIY45468.1 - 0.014 14.8 25.5 0.19 11.1 7.3 2.9 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KIY45468.1 - 0.016 15.8 32.0 0.025 15.1 20.7 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region Tup_N PF08581.10 KIY45468.1 - 0.016 15.5 7.1 0.016 15.5 7.1 4.0 1 1 3 4 4 4 0 Tup N-terminal ADIP PF11559.8 KIY45468.1 - 0.018 15.1 25.5 0.063 13.4 6.5 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KIY45468.1 - 0.019 14.1 20.7 0.16 11.0 12.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 KIY45468.1 - 0.023 15.3 23.7 3.6 8.3 13.2 3.2 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 KIY45468.1 - 0.027 14.5 27.5 0.35 10.9 17.8 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 KIY45468.1 - 0.032 14.8 18.5 0.2 12.2 6.7 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Glyco_hydro_101 PF12905.7 KIY45468.1 - 0.06 12.8 2.4 0.071 12.5 2.4 1.1 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase DUF641 PF04859.12 KIY45468.1 - 0.072 13.4 17.9 3.2 8.1 2.3 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KIY45468.1 - 0.1 11.5 25.1 0.15 10.9 11.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 KIY45468.1 - 0.1 12.8 27.7 0.86 9.8 18.4 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Neuraminidase PF18413.1 KIY45468.1 - 0.11 12.1 1.3 0.16 11.6 1.3 1.3 1 0 0 1 1 1 0 Neuraminidase-like domain DUF3037 PF11236.8 KIY45468.1 - 0.18 12.3 4.6 0.85 10.1 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) DUF3584 PF12128.8 KIY45468.1 - 0.2 9.1 24.6 0.52 7.8 23.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) FapA PF03961.13 KIY45468.1 - 0.25 9.9 16.1 1.3 7.6 1.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A SPATA24 PF15175.6 KIY45468.1 - 0.27 11.1 20.5 0.045 13.6 9.3 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 SlyX PF04102.12 KIY45468.1 - 0.3 11.7 19.6 0.71 10.5 4.0 3.6 2 1 2 4 4 4 0 SlyX IFT57 PF10498.9 KIY45468.1 - 0.43 9.5 18.6 2.4 7.1 18.6 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 KASH_CCD PF14662.6 KIY45468.1 - 0.56 10.0 26.6 0.58 10.0 14.3 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 KIY45468.1 - 0.58 9.5 18.3 0.36 10.1 12.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4600 PF15372.6 KIY45468.1 - 0.66 10.4 16.2 0.2 12.1 10.7 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) SPATA1_C PF15743.5 KIY45468.1 - 0.82 9.7 22.7 2.1 8.4 21.8 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus Tropomyosin_1 PF12718.7 KIY45468.1 - 0.98 9.6 28.2 2.5 8.2 8.9 3.6 1 1 2 3 3 3 0 Tropomyosin like DUF1664 PF07889.12 KIY45468.1 - 1 9.4 12.6 1.6 8.7 7.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 KIY45468.1 - 1.1 10.0 14.0 15 6.4 3.2 3.1 1 1 2 3 3 3 0 Occludin homology domain YlqD PF11068.8 KIY45468.1 - 1.3 9.4 19.9 2.5 8.5 14.3 2.6 1 1 2 3 3 3 0 YlqD protein Leu_zip PF15294.6 KIY45468.1 - 1.4 8.4 21.2 5.5 6.4 12.7 2.3 1 1 2 3 3 3 0 Leucine zipper DHR10 PF18595.1 KIY45468.1 - 2.1 8.4 29.2 0.42 10.7 13.2 3.2 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF5398 PF17376.2 KIY45468.1 - 2.1 9.0 9.0 11 6.7 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5398) DUF5082 PF16888.5 KIY45468.1 - 2.2 8.6 16.0 3.2 8.0 0.3 3.1 1 1 0 3 3 3 0 Domain of unknown function (DUF5082) Lebercilin PF15619.6 KIY45468.1 - 2.3 7.8 28.9 0.83 9.3 15.4 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 KIY45468.1 - 2.4 8.4 26.9 6.2 7.0 19.7 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 KIY45468.1 - 2.8 7.8 22.5 7 6.5 0.3 3.8 2 1 2 4 4 4 0 Septum formation initiator SOAR PF16533.5 KIY45468.1 - 3.1 7.8 13.3 0.62 10.1 7.9 2.4 1 1 1 3 3 3 0 STIM1 Orai1-activating region Phage_GPO PF05929.11 KIY45468.1 - 3.7 7.1 19.5 3.7 7.1 4.5 2.4 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase BST2 PF16716.5 KIY45468.1 - 5.7 7.6 21.2 17 6.1 7.2 3.3 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF4140 PF13600.6 KIY45468.1 - 6 7.4 23.2 6.3 7.3 2.4 3.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.19 KIY45468.1 - 6.7 4.5 14.8 4.7 5.0 1.1 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 KIY45468.1 - 9.2 6.3 24.9 13 5.8 11.0 3.4 1 1 0 2 2 2 0 Prefoldin subunit Bap31_Bap29_C PF18035.1 KIY45468.1 - 9.7 6.3 21.3 0.46 10.5 0.2 4.3 4 1 0 4 4 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Es2 PF09751.9 KIY45469.1 - 3.8e-76 257.6 17.7 9.2e-75 253.0 17.7 2.2 1 1 0 1 1 1 1 Nuclear protein Es2 MIF PF01187.18 KIY45470.1 - 2.3e-21 76.2 0.0 2.6e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) BING4CT PF08149.11 KIY45470.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 BING4CT (NUC141) domain Gln-synt_C PF00120.24 KIY45471.1 - 3.3e-68 230.2 0.0 4.1e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain CFEM PF05730.11 KIY45473.1 - 1.1e-10 41.4 14.1 1.1e-10 41.4 14.1 2.5 2 0 0 2 2 2 1 CFEM domain Transketolase_C PF02780.20 KIY45473.1 - 0.22 11.4 0.9 0.62 10.0 0.2 1.9 1 1 1 2 2 2 0 Transketolase, C-terminal domain Remorin_C PF03763.13 KIY45474.1 - 0.076 12.9 2.4 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Remorin, C-terminal region Nefa_Nip30_N PF10187.9 KIY45476.1 - 2.1e-30 105.2 13.0 2.3e-30 105.0 13.0 1.0 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3629 PF12302.8 KIY45476.1 - 0.064 12.7 0.9 0.079 12.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) VIR_N PF15912.5 KIY45476.1 - 1.1 8.8 5.0 1.2 8.7 5.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Dna2 PF08696.11 KIY45477.1 - 1.3e-55 188.4 0.0 2.2e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KIY45477.1 - 5e-51 173.2 0.0 7.8e-51 172.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY45477.1 - 9.1e-15 55.1 0.0 1.9e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KIY45477.1 - 6.7e-09 36.0 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.6 KIY45477.1 - 9.5e-08 32.0 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY45477.1 - 3.8e-07 30.6 0.0 1.8e-06 28.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KIY45477.1 - 1.8e-06 28.2 0.0 8.9e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KIY45477.1 - 0.013 15.3 0.0 0.3 10.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KIY45477.1 - 0.016 15.6 0.0 0.097 13.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KIY45477.1 - 0.022 14.4 0.1 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 KIY45477.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 KIY45477.1 - 0.029 14.5 0.1 0.57 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KIY45477.1 - 0.036 14.5 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIY45477.1 - 0.054 13.8 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF1660 PF07874.11 KIY45477.1 - 0.064 13.8 0.3 9.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Prophage protein (DUF1660) CbiA PF01656.23 KIY45477.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KIY45477.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KIY45477.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KIY45477.1 - 0.12 11.4 0.0 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 KIY45477.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Tubulin_C PF03953.17 KIY45478.1 - 5.2e-13 49.3 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Hydrophobin PF01185.18 KIY45479.1 - 2.8e-20 72.7 9.4 4.6e-20 72.0 9.4 1.3 1 0 0 1 1 1 1 Fungal hydrophobin VKOR PF07884.14 KIY45479.1 - 0.053 13.7 5.0 0.063 13.5 5.0 1.3 1 0 0 1 1 1 0 Vitamin K epoxide reductase family TPPII_N PF12583.8 KIY45479.1 - 0.16 12.5 3.9 0.25 11.9 3.0 1.6 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Prp19 PF08606.11 KIY45481.1 - 9.7e-33 112.0 3.0 2.2e-32 110.8 3.0 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KIY45481.1 - 3.2e-07 30.9 2.2 0.14 13.1 0.0 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY45481.1 - 3.2e-07 30.5 0.0 0.00047 20.4 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 KIY45481.1 - 4.3e-06 26.8 0.0 1.4e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 U-box domain Frtz PF11768.8 KIY45481.1 - 0.0024 16.3 0.0 0.0034 15.8 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz zf-Nse PF11789.8 KIY45481.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LcrG PF07216.12 KIY45481.1 - 0.045 13.7 1.5 1.5 8.8 1.8 2.3 2 0 0 2 2 2 0 LcrG protein Rtf2 PF04641.12 KIY45481.1 - 0.19 11.1 0.5 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger OPT PF03169.15 KIY45482.1 - 3.9e-176 587.3 50.3 4.4e-176 587.1 50.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2418 PF10332.9 KIY45482.1 - 0.094 13.2 0.5 0.66 10.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) SLS PF14611.6 KIY45483.1 - 1.2e-08 35.0 0.0 3.2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator TauD PF02668.16 KIY45484.1 - 1.4e-52 179.1 1.0 1.8e-52 178.8 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SLX9 PF15341.6 KIY45485.1 - 6.7e-20 71.8 4.0 1.1e-19 71.1 4.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 HAP1_N PF04849.13 KIY45486.1 - 0.0068 15.6 25.0 0.58 9.3 0.0 3.3 3 0 0 3 3 3 3 HAP1 N-terminal conserved region ZapB PF06005.12 KIY45486.1 - 0.12 12.9 31.7 0.68 10.4 1.5 4.8 3 1 1 4 4 4 0 Cell division protein ZapB Aminopep PF10023.9 KIY45486.1 - 0.13 11.7 7.6 0.23 10.8 7.6 1.4 1 0 0 1 1 1 0 Putative aminopeptidase DUF4600 PF15372.6 KIY45486.1 - 0.23 11.9 11.9 0.66 10.4 11.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Macoilin PF09726.9 KIY45486.1 - 1.2 7.6 25.6 0.061 11.9 12.2 2.4 1 1 1 2 2 2 0 Macoilin family Cep57_CLD_2 PF14197.6 KIY45486.1 - 4.2 7.5 22.9 0.02 15.0 8.4 3.9 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF5320 PF17253.2 KIY45486.1 - 6.3 7.9 10.7 3.3 8.8 0.0 4.3 3 1 1 4 4 4 0 Family of unknown function (DUF5320) Rad51 PF08423.11 KIY45487.1 - 8.3e-14 51.5 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 AMP-binding PF00501.28 KIY45488.1 - 8.6e-21 74.0 0.0 4.7e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 KIY45488.1 - 0.02 13.8 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter VWA_3_C PF18571.1 KIY45488.1 - 0.072 13.0 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain MTBP_C PF14920.6 KIY45488.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding PPR_2 PF13041.6 KIY45489.1 - 1.7e-19 69.7 0.0 5.4e-09 36.1 0.0 6.6 6 1 1 7 7 7 3 PPR repeat family PPR_3 PF13812.6 KIY45489.1 - 2.8e-15 56.2 0.0 6.9e-08 32.5 0.0 5.8 6 1 1 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.20 KIY45489.1 - 1.6e-11 43.6 0.4 3.5e-06 26.9 0.0 5.2 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.7 KIY45489.1 - 2e-11 43.4 0.0 7.5e-09 35.1 0.0 4.4 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 KIY45489.1 - 3.3e-09 36.4 0.0 0.0007 19.0 0.0 3.3 3 0 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KIY45489.1 - 0.89 10.5 6.5 3.4 8.7 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Actin PF00022.19 KIY45490.1 - 1.1e-115 386.5 0.0 4.9e-115 384.4 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIY45490.1 - 0.21 10.4 0.0 1.7 7.4 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein MGC-24 PF05283.11 KIY45491.1 - 0.04 14.4 7.0 0.055 13.9 7.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4512 PF14975.6 KIY45491.1 - 0.13 13.0 3.5 0.21 12.4 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Mucin PF01456.17 KIY45491.1 - 0.43 10.6 17.3 0.64 10.0 17.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF515 PF04415.12 KIY45491.1 - 0.63 8.4 19.0 0.79 8.1 19.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.9 KIY45491.1 - 1.2 8.7 19.2 1.6 8.3 19.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Anti-TRAP PF15777.5 KIY45492.1 - 1.9 8.5 6.3 1.2 9.2 2.8 2.2 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_clus PF00172.18 KIY45492.1 - 3.5 7.8 8.1 1.1 9.5 3.3 2.6 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF2A PF08662.11 KIY45493.1 - 5.3e-38 130.9 0.2 6.1e-35 120.9 0.0 3.8 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KIY45493.1 - 2.8e-05 23.9 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KIY45493.1 - 0.00074 20.3 3.8 0.54 11.2 0.1 5.2 6 0 0 6 6 6 1 WD domain, G-beta repeat Hap4_Hap_bind PF10297.9 KIY45494.1 - 1.9e-07 31.0 4.8 6.2e-07 29.3 4.8 2.0 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Tuberculin PF12198.8 KIY45494.1 - 0.043 13.9 2.1 0.18 11.9 0.1 2.6 2 0 0 2 2 2 0 Theoretical tuberculin protein HALZ PF02183.18 KIY45494.1 - 0.063 13.5 1.1 0.12 12.6 1.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper TMCO5 PF14992.6 KIY45494.1 - 0.21 11.1 4.9 0.31 10.6 4.9 1.2 1 0 0 1 1 1 0 TMCO5 family bZIP_1 PF00170.21 KIY45494.1 - 1.1 9.4 26.4 0.026 14.6 16.2 2.5 2 1 0 2 2 2 0 bZIP transcription factor EamA PF00892.20 KIY45495.1 - 6e-10 39.4 32.2 5.7e-07 29.8 9.7 3.0 2 1 0 2 2 2 2 EamA-like transporter family DUF3955 PF13127.6 KIY45495.1 - 0.031 14.1 2.2 0.031 14.1 2.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3955) PUNUT PF16913.5 KIY45495.1 - 0.039 13.2 18.7 0.47 9.6 18.7 2.1 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport DUF1003 PF06210.11 KIY45495.1 - 5.8 7.1 5.6 4.3 7.5 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) Spc7 PF08317.11 KIY45496.1 - 2.2e-71 240.3 18.1 2.6e-71 240.1 18.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KIY45496.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Spc7_C2 Atg14 PF10186.9 KIY45496.1 - 0.13 11.3 7.0 0.2 10.7 7.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF836 PF05768.14 KIY45496.1 - 0.3 11.5 3.0 1.4 9.4 3.0 2.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) zf-C4H2 PF10146.9 KIY45496.1 - 0.41 10.9 6.1 0.79 10.0 6.1 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein GAS PF13851.6 KIY45496.1 - 0.7 9.2 25.3 0.86 8.9 11.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.13 KIY45496.1 - 1.1 9.4 18.7 0.26 11.4 10.7 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Wtap PF17098.5 KIY45496.1 - 1.4 8.8 18.3 0.23 11.4 9.2 3.1 2 1 1 3 3 3 0 WTAP/Mum2p family DUF1664 PF07889.12 KIY45496.1 - 3.1 7.9 6.3 8.8 6.4 2.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 KIY45496.1 - 9.6 5.0 24.0 22 3.7 23.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Arylsulfotran_2 PF14269.6 KIY45497.1 - 5.6e-30 104.7 0.0 8.6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY45497.1 - 1.9e-15 56.6 0.0 8.1e-14 51.3 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) AKAP7_NLS PF10469.9 KIY45498.1 - 4.9e-28 98.5 0.0 8.6e-28 97.6 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KIY45498.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily K_trans PF02705.16 KIY45499.1 - 8e-172 572.5 9.8 1.1e-171 572.0 9.8 1.2 1 0 0 1 1 1 1 K+ potassium transporter Asp PF00026.23 KIY45500.1 - 0.0003 20.3 6.7 0.017 14.6 6.7 3.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DAO PF01266.24 KIY45501.1 - 8.3e-07 28.9 0.0 9e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIY45501.1 - 8e-05 22.0 0.0 8.7e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KIY45501.1 - 0.0038 17.2 0.0 0.0047 16.9 0.0 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIY45501.1 - 0.0065 16.7 0.0 0.0083 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY45501.1 - 0.0096 15.0 0.0 0.011 14.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIY45501.1 - 0.059 12.4 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY45501.1 - 0.067 12.4 0.1 0.075 12.3 0.1 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KIY45501.1 - 0.1 11.4 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 MCRA family AlaDh_PNT_C PF01262.21 KIY45501.1 - 0.15 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DIE2_ALG10 PF04922.12 KIY45502.1 - 2.2e-121 405.8 8.0 2.7e-121 405.6 8.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Arm PF00514.23 KIY45504.1 - 1.3e-69 228.3 34.0 1.2e-12 47.4 0.2 11.8 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIY45504.1 - 2.5e-20 72.5 11.2 0.00053 20.4 0.2 8.5 7 2 1 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 KIY45504.1 - 1.1e-17 64.2 9.2 0.0013 19.1 0.0 7.5 2 2 5 7 7 7 7 HEAT repeats HEAT PF02985.22 KIY45504.1 - 1.6e-13 49.6 19.1 0.55 10.6 0.0 9.7 10 0 0 10 10 10 5 HEAT repeat Adaptin_N PF01602.20 KIY45504.1 - 1.1e-09 37.5 13.1 1.1e-06 27.6 1.5 3.1 1 1 2 3 3 3 3 Adaptin N terminal region KAP PF05804.12 KIY45504.1 - 4e-09 35.2 3.0 6.1e-09 34.6 3.0 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 KIY45504.1 - 9e-08 31.9 12.1 3.8e-05 23.3 4.3 2.8 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 KIY45504.1 - 9.4e-07 28.4 11.6 0.018 14.3 5.4 4.5 1 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KIY45504.1 - 6.9e-06 26.2 8.4 0.19 11.7 0.7 5.3 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KIY45504.1 - 0.0008 19.9 7.6 18 6.4 0.2 7.2 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 KIY45504.1 - 0.0029 18.2 0.4 3.5 8.3 0.1 3.6 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 KIY45504.1 - 0.02 14.9 10.7 0.62 10.0 0.1 4.3 2 1 2 5 5 5 0 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 KIY45504.1 - 0.12 12.5 1.5 1.1 9.3 0.1 3.3 2 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain YqfD PF06898.11 KIY45504.1 - 0.25 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD NopRA1 PF16201.5 KIY45504.1 - 4.8 6.7 6.6 33 4.0 0.0 4.1 4 1 0 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Aa_trans PF01490.18 KIY45508.1 - 2.4e-83 280.2 32.3 2.8e-83 279.9 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_23 PF13489.6 KIY45509.1 - 1.9e-16 60.3 0.0 2.2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY45509.1 - 1.8e-15 57.4 0.0 3.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY45509.1 - 2.9e-15 56.7 0.0 5.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY45509.1 - 1.3e-13 51.0 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY45509.1 - 6.2e-12 46.1 0.0 9.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY45509.1 - 6.6e-08 32.2 0.0 1.8e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIY45509.1 - 0.00052 19.6 0.0 0.00085 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIY45509.1 - 0.0019 17.7 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KIY45509.1 - 0.003 17.5 0.0 0.0066 16.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KIY45509.1 - 0.0037 16.4 0.0 0.0052 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KIY45509.1 - 0.0053 16.1 0.0 0.0063 15.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KIY45509.1 - 0.012 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Cons_hypoth95 PF03602.15 KIY45509.1 - 0.054 13.1 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 N6_N4_Mtase PF01555.18 KIY45509.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Romo1 PF10247.9 KIY45510.1 - 9e-19 67.6 13.4 1.5e-11 44.4 1.9 2.3 1 1 1 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 Pex2_Pex12 PF04757.14 KIY45511.1 - 2.1e-25 89.7 5.7 1.2e-23 84.0 5.7 2.1 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KIY45511.1 - 6.8e-11 41.9 4.5 9.5e-11 41.4 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY45511.1 - 9e-09 35.1 6.4 1.3e-08 34.5 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY45511.1 - 1.8e-08 34.1 6.7 2.8e-08 33.5 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY45511.1 - 2.4e-08 34.2 8.6 3.7e-08 33.6 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIY45511.1 - 3e-08 33.4 4.7 4.6e-08 32.8 4.7 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIY45511.1 - 2.8e-07 30.4 2.5 3.1e-07 30.3 1.3 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KIY45511.1 - 5.1e-06 26.7 5.3 1e-05 25.7 5.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KIY45511.1 - 5.5e-06 26.2 6.8 9e-06 25.6 6.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIY45511.1 - 0.00046 20.3 6.3 0.00082 19.5 6.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KIY45511.1 - 0.0054 16.7 1.1 0.0094 16.0 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KIY45511.1 - 0.024 14.8 4.0 0.042 14.0 4.0 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 TerY_C PF15616.6 KIY45511.1 - 0.037 14.1 1.9 0.061 13.4 1.9 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.6 KIY45511.1 - 0.096 12.5 5.3 0.17 11.7 5.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KIY45511.1 - 0.79 9.5 2.9 1.9 8.3 2.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 KIY45511.1 - 3.9 7.8 8.1 11 6.3 8.1 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain PolyA_pol PF01743.20 KIY45512.1 - 2.3e-19 70.1 0.0 4.4e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KIY45512.1 - 0.00011 21.9 0.0 0.0003 20.5 0.0 1.8 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HemN_C PF06969.16 KIY45512.1 - 0.055 13.5 0.1 3.3 7.8 0.0 3.1 3 0 0 3 3 3 0 HemN C-terminal domain HNH_2 PF13391.6 KIY45513.1 - 0.13 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease GTP_EFTU PF00009.27 KIY45516.1 - 1.2e-57 194.6 0.0 1.9e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIY45516.1 - 1.6e-16 60.1 0.0 3.9e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KIY45516.1 - 5.2e-09 36.1 0.0 9.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KIY45516.1 - 4.7e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIY45516.1 - 0.03 14.7 0.0 0.076 13.4 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 SRPRB PF09439.10 KIY45516.1 - 0.13 11.6 0.1 0.73 9.2 0.1 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_IV PF03764.18 KIY45516.1 - 0.16 11.8 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor G, domain IV Aminotran_1_2 PF00155.21 KIY45517.1 - 1.6e-35 122.9 0.0 2.7e-35 122.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KIY45517.1 - 0.015 14.0 0.0 0.029 13.1 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain S1-P1_nuclease PF02265.16 KIY45518.1 - 2.3e-09 37.4 0.0 2.5e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease p450 PF00067.22 KIY45519.1 - 8.8e-70 235.7 0.0 2e-69 234.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF4568 PF15132.6 KIY45519.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) HsbA PF12296.8 KIY45520.1 - 0.023 15.1 6.4 0.033 14.6 6.4 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A LXG PF04740.12 KIY45520.1 - 0.038 13.7 1.3 0.074 12.8 1.3 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily Exo70 PF03081.15 KIY45520.1 - 0.096 11.7 0.4 0.2 10.7 0.3 1.4 1 1 1 2 2 2 0 Exo70 exocyst complex subunit Spore_III_AB PF09548.10 KIY45520.1 - 0.12 12.5 0.0 6.3 6.9 0.0 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Spidroin_MaSp PF11260.8 KIY45520.1 - 0.72 10.2 13.6 1.3 9.4 4.0 3.1 1 1 2 3 3 3 0 Major ampullate spidroin 1 and 2 GTP_EFTU PF00009.27 KIY45521.1 - 3.8e-42 144.0 0.0 4.2e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EIIA-man PF03610.16 KIY45521.1 - 0.022 15.0 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component MMR_HSR1 PF01926.23 KIY45521.1 - 0.041 14.0 0.0 0.063 13.4 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase F-box-like PF12937.7 KIY45522.1 - 0.0015 18.4 1.2 0.0095 15.8 0.5 2.6 2 1 0 2 2 2 1 F-box-like LXG PF04740.12 KIY45523.1 - 0.00085 19.1 3.2 0.51 10.0 0.6 2.2 1 1 1 2 2 2 2 LXG domain of WXG superfamily HsbA PF12296.8 KIY45523.1 - 0.0027 18.1 6.9 0.0038 17.6 6.9 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A EF-G-binding_N PF07299.11 KIY45523.1 - 0.019 15.5 0.7 0.18 12.4 0.2 2.1 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF1542 PF07564.11 KIY45523.1 - 0.032 14.3 0.4 0.058 13.5 0.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Exo70 PF03081.15 KIY45523.1 - 0.099 11.7 0.4 0.27 10.3 0.4 1.6 1 1 1 2 2 2 0 Exo70 exocyst complex subunit Gemini_AC4_5_2 PF08464.10 KIY45523.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Arylsulfotran_2 PF14269.6 KIY45524.1 - 5.8e-10 39.0 0.8 5.5e-09 35.8 0.8 2.2 1 1 1 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY45524.1 - 1e-05 24.7 0.2 0.0079 15.1 0.4 2.2 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) DUF4774 PF15999.5 KIY45524.1 - 0.0091 15.8 0.2 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4774) Luteo_coat PF00894.18 KIY45524.1 - 0.075 12.9 0.2 0.88 9.5 0.0 2.4 3 0 0 3 3 3 0 Luteovirus coat protein HTH_23 PF13384.6 KIY45525.1 - 8.6e-10 38.1 0.1 4.8e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KIY45525.1 - 2e-08 34.1 0.0 3.4e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KIY45525.1 - 3.4e-07 30.3 0.0 6.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 KIY45525.1 - 1.6e-06 28.0 0.0 0.0041 17.1 0.0 3.2 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KIY45525.1 - 5e-05 23.8 0.0 0.00013 22.5 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_AraC PF00165.23 KIY45525.1 - 0.0078 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family AbiEi_4 PF13338.6 KIY45525.1 - 0.0095 16.1 0.0 0.14 12.3 0.0 2.6 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin HTH_17 PF12728.7 KIY45525.1 - 0.01 16.0 0.2 0.041 14.1 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Terminase_5 PF06056.12 KIY45525.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_38 PF13936.6 KIY45525.1 - 0.02 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KIY45525.1 - 0.047 13.9 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 Transposase CPSase_L_D3 PF02787.19 KIY45525.1 - 0.093 13.1 0.1 1.1 9.6 0.0 2.4 2 1 1 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain UPF0175 PF03683.13 KIY45525.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_Crp_2 PF13545.6 KIY45525.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4515 PF14988.6 KIY45527.1 - 0.02 14.7 0.4 0.031 14.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Stathmin PF00836.19 KIY45528.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Stathmin family Piwi PF02171.17 KIY45529.1 - 5e-15 55.5 0.0 2.3e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Piwi domain HsbA PF12296.8 KIY45530.1 - 0.0067 16.9 6.4 0.0098 16.3 6.4 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A LXG PF04740.12 KIY45530.1 - 0.16 11.7 2.9 1.3 8.7 2.5 1.9 1 1 1 2 2 2 0 LXG domain of WXG superfamily HsbA PF12296.8 KIY45532.1 - 0.00072 20.0 7.6 0.00093 19.6 7.6 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Exo70 PF03081.15 KIY45532.1 - 0.13 11.3 0.2 0.2 10.7 0.2 1.4 1 1 0 1 1 1 0 Exo70 exocyst complex subunit EF-G-binding_N PF07299.11 KIY45532.1 - 0.15 12.6 0.4 0.51 10.9 0.3 1.8 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Phage_holin_2_4 PF16082.5 KIY45532.1 - 0.85 9.4 3.4 2.6 7.8 0.6 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like F-box-like PF12937.7 KIY45533.1 - 1.4e-06 28.1 1.0 1.4e-06 28.1 1.0 2.5 2 1 0 2 2 2 1 F-box-like Ste5 PF11610.8 KIY45533.1 - 0.93 9.4 5.9 0.098 12.6 0.7 2.1 3 0 0 3 3 3 0 Scaffold protein Ste5, Fus3-binding region Pyridox_ox_2 PF12900.7 KIY45534.1 - 8e-15 55.1 0.0 2.2e-12 47.2 0.0 2.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HsbA PF12296.8 KIY45535.1 - 0.019 15.4 9.5 0.032 14.7 9.5 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A LXG PF04740.12 KIY45535.1 - 0.028 14.2 2.9 3.3 7.4 1.1 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily EF-G-binding_N PF07299.11 KIY45535.1 - 0.2 12.2 1.5 0.55 10.8 0.9 1.9 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF1542 PF07564.11 KIY45535.1 - 0.28 11.3 2.1 0.48 10.6 2.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Pho88 PF10032.9 KIY45536.1 - 3.1e-76 254.7 0.5 3.4e-76 254.5 0.5 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pyridox_ox_2 PF12900.7 KIY45537.1 - 2.5e-23 82.6 0.1 1.1e-21 77.3 0.1 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F-box-like PF12937.7 KIY45538.1 - 6.1e-07 29.2 1.0 3.5e-06 26.8 1.0 2.3 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY45538.1 - 0.072 13.1 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.33 KIY45538.1 - 2.6 8.0 5.7 2.2 8.3 1.4 2.9 2 1 0 2 2 2 0 F-box domain HsbA PF12296.8 KIY45539.1 - 0.041 14.3 9.4 0.07 13.6 9.4 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DUF948 PF06103.11 KIY45539.1 - 0.076 13.3 7.1 0.054 13.8 1.5 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Delta_lysin PF05372.11 KIY45539.1 - 0.6 9.4 0.1 0.6 9.4 0.1 2.6 2 0 0 2 2 2 0 Delta lysin family Pyridox_ox_2 PF12900.7 KIY45540.1 - 6.3e-40 136.4 0.0 8.5e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F-box-like PF12937.7 KIY45541.1 - 5.6e-06 26.1 0.5 3.3e-05 23.7 0.5 2.3 1 1 0 1 1 1 1 F-box-like ABC_tran_CTD PF16326.5 KIY45541.1 - 0.052 13.8 0.3 0.13 12.5 0.2 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Pyridox_ox_2 PF12900.7 KIY45542.1 - 6.3e-40 136.4 0.0 8.4e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Arylsulfotran_2 PF14269.6 KIY45545.1 - 7.4e-38 130.6 1.9 1.5e-37 129.6 1.9 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY45545.1 - 7.5e-13 48.1 3.1 1.6e-11 43.7 3.1 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans PF04082.18 KIY45546.1 - 1.1e-24 86.9 0.2 1.8e-24 86.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.12 KIY45546.1 - 0.03 14.2 0.1 0.077 12.9 0.1 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SKN1 PF03935.15 KIY45548.1 - 8.2e-36 123.4 0.6 9.4e-36 123.3 0.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) F-box-like PF12937.7 KIY45549.1 - 8.6e-05 22.4 0.1 0.00051 19.9 0.1 2.3 1 1 0 1 1 1 1 F-box-like SDA1 PF05285.12 KIY45549.1 - 0.18 11.2 19.4 0.24 10.8 19.4 1.1 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.8 KIY45549.1 - 0.36 9.7 12.8 0.51 9.2 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SAPS PF04499.15 KIY45549.1 - 1.7 7.3 4.5 2.4 6.8 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.14 KIY45549.1 - 9.5 6.0 11.5 19 5.0 11.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CoA_transf_3 PF02515.17 KIY45550.1 - 7.3e-122 407.0 0.0 8.4e-122 406.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DIOX_N PF14226.6 KIY45551.1 - 6.1e-21 75.4 0.0 1.5e-19 70.9 0.0 2.4 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY45551.1 - 3.1e-11 43.6 0.0 7.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aldo_ket_red PF00248.21 KIY45552.1 - 4.4e-48 164.0 0.0 5e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ferric_reduct PF01794.19 KIY45553.1 - 2.9e-21 75.9 6.2 7.8e-21 74.5 6.2 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIY45553.1 - 1.6e-10 41.3 0.0 3.1e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIY45553.1 - 7e-08 32.5 0.0 1.8e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KIY45553.1 - 0.0012 19.5 0.0 0.0026 18.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DSPc PF00782.20 KIY45554.1 - 3.1e-28 98.2 0.0 4e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIY45554.1 - 0.015 15.6 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain DUF3813 PF12758.7 KIY45554.1 - 0.022 15.1 0.0 0.57 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) DsrC PF04358.13 KIY45554.1 - 0.036 14.6 0.0 0.088 13.3 0.0 1.6 2 0 0 2 2 2 0 DsrC like protein Y_phosphatase3 PF13350.6 KIY45554.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family cobW PF02492.19 KIY45555.1 - 2.7e-45 154.1 0.0 4.7e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KIY45555.1 - 6.3e-07 29.2 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KIY45555.1 - 0.00011 21.8 0.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY45555.1 - 0.00017 21.6 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY45555.1 - 0.00027 20.9 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 KIY45555.1 - 0.0039 16.2 0.0 0.061 12.3 0.0 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KIY45555.1 - 0.0044 17.3 0.0 0.017 15.4 0.0 2.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KIY45555.1 - 0.0053 16.9 0.0 0.0093 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 KIY45555.1 - 0.039 13.4 0.1 7.5 6.0 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.27 KIY45555.1 - 0.098 13.2 0.0 0.3 11.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 KIY45555.1 - 0.1 13.2 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KIY45555.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MobB PF03205.14 KIY45555.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 KIY45555.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Hpt PF01627.23 KIY45556.1 - 8.2e-11 42.0 0.1 1e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 Hpt domain NuiA PF07924.11 KIY45556.1 - 0.0099 16.3 0.0 0.017 15.5 0.0 1.3 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein F-box-like PF12937.7 KIY45557.1 - 2.5e-07 30.5 0.2 1.5e-06 28.0 0.2 2.4 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY45557.1 - 0.034 14.6 0.1 13 6.4 0.0 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Transketolase_C PF02780.20 KIY45558.1 - 2.4e-07 30.7 0.0 6.1e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KIY45558.1 - 1.2e-05 25.0 0.1 2.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_N PF00456.21 KIY45558.1 - 3.7e-05 22.8 0.1 6.3e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 KIY45558.1 - 0.00014 20.9 0.1 0.00024 20.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KIY45558.1 - 0.00077 19.3 0.2 0.0036 17.1 0.2 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short PF00106.25 KIY45559.1 - 4.5e-43 147.0 0.1 8.4e-43 146.1 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY45559.1 - 2.4e-28 99.3 0.1 3.3e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY45559.1 - 2.5e-07 30.8 0.5 9.5e-07 28.9 0.5 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIY45559.1 - 6.4e-05 22.9 0.0 0.00011 22.2 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY45559.1 - 0.0011 18.5 0.1 0.0037 16.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KIY45559.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KIY45559.1 - 0.031 13.8 0.2 5.5 6.5 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family BTB PF00651.31 KIY45560.1 - 1.3e-09 38.3 0.0 3.5e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Na_Ca_ex PF01699.24 KIY45561.1 - 2.7e-18 66.3 41.5 2.4e-13 50.3 11.3 3.3 3 1 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 KIY45561.1 - 2.3e-12 47.4 5.2 2.3e-12 47.4 5.2 4.0 3 0 0 3 3 3 1 Inner membrane component domain MMS1_N PF10433.9 KIY45562.1 - 8.9e-40 136.7 0.0 1.9e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KIY45562.1 - 1.7e-27 96.6 0.2 1.9e-26 93.2 0.1 2.4 2 0 0 2 2 2 1 CPSF A subunit region zf-C2H2_11 PF16622.5 KIY45563.1 - 0.027 14.2 1.5 0.027 14.2 1.5 1.6 2 0 0 2 2 2 0 zinc-finger C2H2-type DIOX_N PF14226.6 KIY45564.1 - 1.5e-15 58.0 0.1 3.8e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY45564.1 - 4.4e-13 49.6 0.0 1.6e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 KIY45565.1 - 1.4e-15 57.5 0.0 2.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY45565.1 - 1e-10 41.9 0.0 2.6e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit adh_short PF00106.25 KIY45567.1 - 0.014 14.9 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DIOX_N PF14226.6 KIY45568.1 - 2.9e-16 60.3 0.2 8.7e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY45568.1 - 4.7e-12 46.3 0.0 9.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_1 PF00667.20 KIY45569.1 - 8.3e-55 185.8 0.0 7e-54 182.7 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KIY45569.1 - 1.5e-30 106.3 0.6 1.5e-30 106.3 0.6 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KIY45569.1 - 4.4e-20 72.3 0.0 1.2e-19 70.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain LPD5 PF18799.1 KIY45570.1 - 0.051 14.0 0.0 0.059 13.8 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 DPBB_1 PF03330.18 KIY45573.1 - 0.0061 16.8 0.1 0.012 15.9 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase FCH PF00611.23 KIY45574.1 - 1.5e-13 50.8 1.7 2.9e-13 49.9 0.2 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 KIY45574.1 - 3e-13 49.4 3.7 3e-13 49.4 3.7 1.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_9 PF14604.6 KIY45574.1 - 9.9e-10 38.1 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY45574.1 - 3.3e-05 23.4 0.0 6.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIY45574.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KIY45574.1 - 0.059 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain FYVE PF01363.21 KIY45574.1 - 0.094 12.9 1.1 0.29 11.3 1.1 1.8 1 0 0 1 1 1 0 FYVE zinc finger Remorin_C PF03763.13 KIY45574.1 - 0.27 11.1 4.5 6.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Remorin, C-terminal region zf-C2H2_4 PF13894.6 KIY45575.1 - 0.024 15.4 0.3 9.4 7.4 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY45575.1 - 0.14 12.6 1.4 11 6.8 0.0 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type CDC45 PF02724.14 KIY45575.1 - 9.1 4.4 6.2 13 3.9 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein IGR PF09597.10 KIY45576.1 - 2.8e-14 53.0 0.4 2.8e-14 53.0 0.4 1.6 2 0 0 2 2 2 1 IGR protein motif Mon1 PF03164.14 KIY45577.1 - 1.7e-90 304.1 0.0 4.5e-69 233.5 0.0 2.2 1 1 1 2 2 2 2 Trafficking protein Mon1 EBP PF05241.12 KIY45578.1 - 1.2e-57 194.2 10.8 1.5e-57 194.0 10.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein Sugar_tr PF00083.24 KIY45579.1 - 1.3e-84 284.7 14.2 1.5e-84 284.4 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY45579.1 - 6.5e-32 110.8 15.9 6.5e-32 110.8 15.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KIY45579.1 - 0.00037 18.9 0.7 0.0039 15.5 0.6 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family UPF0172 PF03665.13 KIY45580.1 - 1.6e-55 188.1 0.0 1.8e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 KIY45580.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Viral_Beta_CD PF04530.12 KIY45581.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral Beta C/D like family RIO1 PF01163.22 KIY45582.1 - 8.2e-71 237.5 0.1 1.6e-70 236.6 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KIY45582.1 - 0.014 14.2 0.1 0.037 12.8 0.1 1.6 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KIY45582.1 - 0.21 11.5 2.2 5 7.0 0.3 2.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family GPI-anchored PF10342.9 KIY45583.1 - 0.00016 22.3 0.0 0.00022 21.9 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amidohydro_1 PF01979.20 KIY45584.1 - 9e-46 156.8 0.0 1.2e-45 156.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIY45584.1 - 4.3e-09 36.4 0.1 5.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family NIR_SIR PF01077.22 KIY45585.1 - 3.7e-46 156.5 0.0 3.3e-42 143.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KIY45585.1 - 1.3e-26 92.2 0.1 1.2e-14 53.9 0.0 2.7 2 1 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KIY45585.1 - 1.5e-20 73.9 0.0 4.4e-20 72.4 0.0 1.9 1 0 0 1 1 1 1 Flavodoxin Septin PF00735.18 KIY45586.1 - 6e-29 101.2 0.0 7.3e-28 97.6 0.0 2.2 1 1 0 1 1 1 1 Septin Zn_clus PF00172.18 KIY45586.1 - 1.4e-14 54.0 18.7 1e-08 35.2 6.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 KIY45587.1 - 4.2e-53 177.3 3.8 1.1e-17 63.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIY45587.1 - 0.00028 20.1 0.1 0.036 13.2 0.0 2.8 2 2 0 2 2 2 2 Gammaproteobacterial serine protease GPI-anchored PF10342.9 KIY45588.1 - 0.0017 19.1 0.0 0.0019 18.9 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HEAT PF02985.22 KIY45589.1 - 0.0041 17.3 0.9 0.15 12.4 0.1 3.8 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KIY45589.1 - 2.4 8.8 5.9 5.6 7.6 0.9 3.8 2 1 1 3 3 3 0 HEAT-like repeat Macoilin PF09726.9 KIY45591.1 - 0.26 9.8 17.8 0.33 9.5 17.8 1.1 1 0 0 1 1 1 0 Macoilin family Na_H_Exchanger PF00999.21 KIY45592.1 - 4.9e-55 186.9 44.0 7.2e-55 186.3 44.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Eaf7 PF07904.13 KIY45594.1 - 8.8e-17 61.4 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Sugar_tr PF00083.24 KIY45595.1 - 4.3e-112 375.3 23.4 4.9e-112 375.1 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY45595.1 - 3.6e-17 62.3 50.8 9.2e-14 51.1 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gaa1 PF04114.14 KIY45595.1 - 0.049 12.7 4.7 0.076 12.0 0.7 2.3 2 1 0 2 2 2 0 Gaa1-like, GPI transamidase component BUD22 PF09073.10 KIY45596.1 - 2.1e-73 248.1 20.8 2.5e-73 247.9 20.8 1.1 1 0 0 1 1 1 1 BUD22 DUF4196 PF13846.6 KIY45596.1 - 0.017 15.3 4.5 0.017 15.3 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) DUF4573 PF15140.6 KIY45597.1 - 0.017 14.9 0.2 0.022 14.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) zf-HIT PF04438.16 KIY45597.1 - 0.17 11.8 8.0 0.5 10.3 8.0 1.8 1 1 0 1 1 1 0 HIT zinc finger Transposase_21 PF02992.14 KIY45598.1 - 1.3e-06 27.9 0.4 4.1e-06 26.2 0.1 1.8 1 1 1 2 2 2 1 Transposase family tnp2 Pro_CA PF00484.19 KIY45599.1 - 1.7e-14 54.4 0.0 2.9e-14 53.6 0.0 1.3 1 1 0 1 1 1 1 Carbonic anhydrase DUF2147 PF09917.9 KIY45599.1 - 0.077 13.7 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) DUF3435 PF11917.8 KIY45601.1 - 0.024 13.6 0.1 0.068 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) Phage_integrase PF00589.22 KIY45601.1 - 0.049 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Phage integrase family Ribosomal_L22 PF00237.19 KIY45602.1 - 1.2e-36 125.1 0.1 1.8e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RE_Eco29kI PF09517.10 KIY45602.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Eco29kI restriction endonuclease RasGEF PF00617.19 KIY45603.1 - 1e-18 68.2 0.2 1.8e-18 67.3 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY45603.1 - 8.1e-11 42.1 0.1 3.3e-10 40.2 0.1 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif UQ_con PF00179.26 KIY45604.1 - 2.7e-49 166.4 0.0 3.1e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY45604.1 - 0.00077 19.2 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B ATP-synt_S1 PF05827.12 KIY45605.1 - 0.097 12.5 0.3 9.5 6.0 0.0 2.5 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) RGS PF00615.19 KIY45605.1 - 0.12 12.6 0.6 0.22 11.8 0.6 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain DUF5131 PF07505.11 KIY45605.1 - 0.24 10.8 0.8 0.31 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5131) HECT PF00632.25 KIY45606.1 - 4.4e-94 315.4 0.0 5.9e-94 315.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KIY45606.1 - 1.5e-37 127.3 17.3 6.7e-13 48.5 3.7 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KIY45606.1 - 1.1e-16 60.9 0.1 2.3e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 C2 domain ATP-synt_ab PF00006.25 KIY45608.1 - 1.5e-67 227.4 0.0 2.1e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KIY45608.1 - 4.4e-13 49.5 0.5 8e-13 48.7 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 KIY45608.1 - 0.076 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TFCD_C PF12612.8 KIY45609.1 - 6.5e-35 120.7 0.0 1.2e-33 116.5 0.0 3.2 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KIY45609.1 - 1.1e-05 25.3 7.3 0.011 15.9 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KIY45609.1 - 0.00027 21.5 0.2 0.084 13.5 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KIY45609.1 - 0.0016 18.5 0.8 0.047 13.7 0.0 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIY45609.1 - 0.0017 18.8 8.2 0.14 12.7 0.3 5.1 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 KIY45609.1 - 0.0017 18.7 3.9 3.7 8.0 0.0 5.3 6 1 0 6 6 6 1 HEAT repeats RTP1_C1 PF10363.9 KIY45609.1 - 0.0096 16.1 0.1 0.097 12.9 0.0 2.7 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KIY45609.1 - 0.083 11.4 0.8 3.5 6.1 0.0 3.4 4 1 0 4 4 4 0 Adaptin N terminal region Tcp11 PF05794.13 KIY45611.1 - 2.3e-70 237.9 0.0 4.9e-70 236.8 0.0 1.5 1 1 0 1 1 1 1 T-complex protein 11 PP2C PF00481.21 KIY45612.1 - 7.8e-81 271.5 0.0 1.3e-80 270.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C CS PF04969.16 KIY45613.1 - 2.8e-11 44.3 0.0 1.2e-10 42.2 0.0 2.0 2 0 0 2 2 2 1 CS domain Bac_luciferase PF00296.20 KIY45613.1 - 0.014 14.8 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase Alg6_Alg8 PF03155.15 KIY45614.1 - 2.3e-132 442.4 17.6 3e-132 442.0 17.6 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Alliinase_C PF04864.13 KIY45615.1 - 0.052 12.4 0.1 0.077 11.9 0.1 1.2 1 0 0 1 1 1 0 Allinase FAM75 PF14650.6 KIY45615.1 - 0.054 13.1 0.5 0.077 12.5 0.5 1.1 1 0 0 1 1 1 0 FAM75 family SOR_SNZ PF01680.17 KIY45616.1 - 1.3e-110 368.0 6.3 1.9e-110 367.5 6.3 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KIY45616.1 - 5e-09 35.8 6.7 8.9e-08 31.7 0.2 2.4 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KIY45616.1 - 1.3e-05 24.5 0.3 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 KIY45616.1 - 0.00026 20.2 0.3 0.015 14.5 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 KIY45616.1 - 0.0039 16.4 0.1 0.085 12.0 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.15 KIY45616.1 - 0.0098 15.3 5.0 0.082 12.3 0.1 2.3 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KIY45616.1 - 0.016 14.7 0.2 0.18 11.2 0.0 2.4 2 1 0 2 2 2 0 Histidine biosynthesis protein TetR_C_27 PF17935.1 KIY45616.1 - 0.031 14.3 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RNA_pol_Rpc4 PF05132.14 KIY45616.1 - 0.11 12.9 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 4HBT PF03061.22 KIY45617.1 - 8.6e-12 45.3 0.4 1.3e-11 44.7 0.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Peptidase_M23 PF01551.22 KIY45617.1 - 0.00061 19.9 0.0 0.45 10.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M23 Kelch_2 PF07646.15 KIY45618.1 - 2.4e-17 62.1 4.3 0.00015 21.6 0.0 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KIY45618.1 - 8.5e-17 60.8 5.2 0.0005 20.3 0.0 5.0 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KIY45618.1 - 9.1e-17 60.8 0.0 3.3e-05 23.8 0.0 4.0 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KIY45618.1 - 3.2e-15 55.4 1.1 5.4e-05 22.7 0.4 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 KIY45618.1 - 4.5e-11 42.8 9.5 2.3e-08 34.1 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KIY45618.1 - 5.5e-08 32.6 0.6 0.29 11.2 0.2 4.1 4 0 0 4 4 4 3 Kelch motif BTB PF00651.31 KIY45618.1 - 0.011 16.0 0.0 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain zf-CRD PF17979.1 KIY45619.1 - 1.1e-10 41.8 0.0 1.1e-10 41.8 0.0 2.6 2 1 1 3 3 2 1 Cysteine rich domain with multizinc binding regions zf-RING_2 PF13639.6 KIY45619.1 - 7.9e-08 32.5 9.6 7.9e-08 32.5 9.6 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY45619.1 - 3.2e-07 30.1 9.3 3.2e-07 30.1 9.3 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY45619.1 - 1.2e-06 28.2 6.8 1.2e-06 28.2 6.8 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY45619.1 - 1.7e-06 27.8 8.1 1.7e-06 27.8 8.1 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY45619.1 - 0.00033 20.6 8.5 0.00033 20.6 8.5 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.6 KIY45619.1 - 0.0032 17.3 6.8 0.0032 17.3 6.8 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIY45619.1 - 0.0032 17.7 5.1 0.0032 17.7 5.1 2.6 3 0 0 3 3 3 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KIY45619.1 - 0.0053 16.6 9.9 0.0053 16.6 9.9 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIY45619.1 - 0.0068 16.4 7.1 0.0068 16.4 7.1 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 KIY45619.1 - 0.021 14.6 1.7 0.078 12.8 1.4 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KIY45619.1 - 0.41 10.3 15.3 2.6 7.8 7.1 3.7 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Zn_clus PF00172.18 KIY45620.1 - 4.9e-07 29.8 11.6 1e-06 28.7 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 KIY45621.1 - 2e-49 167.9 0.3 4.2e-49 166.9 0.1 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KIY45621.1 - 7.7e-09 36.1 0.1 0.0002 22.1 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4504 PF14953.6 KIY45622.1 - 0.00011 21.7 0.1 0.011 15.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) ILVD_EDD PF00920.21 KIY45627.1 - 6.8e-207 688.2 0.1 7.7e-207 688.0 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Putative_PNPOx PF01243.20 KIY45628.1 - 2.2e-19 69.4 0.1 3.6e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KIY45628.1 - 1.2e-17 63.7 2.9 2.4e-17 62.7 2.9 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region adh_short_C2 PF13561.6 KIY45630.1 - 1.7e-45 155.4 0.3 8.1e-44 149.9 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY45630.1 - 9.3e-37 126.4 0.2 7.8e-36 123.4 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIY45630.1 - 3.1e-05 23.9 0.0 6.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY45630.1 - 0.02 14.3 0.1 0.03 13.8 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIY45630.1 - 0.022 15.0 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sec1 PF00995.23 KIY45631.1 - 9.7e-118 394.9 0.0 1.2e-117 394.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.12 KIY45631.1 - 1.6e-79 266.8 0.1 2.4e-79 266.3 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KIY45631.1 - 1e-20 73.9 0.2 1e-20 73.9 0.2 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RTA1 PF04479.13 KIY45633.1 - 2.3e-51 174.3 5.0 3.3e-51 173.8 5.0 1.2 1 0 0 1 1 1 1 RTA1 like protein Nas2_N PF18265.1 KIY45634.1 - 9.3e-25 86.4 0.0 1.3e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KIY45634.1 - 2.3e-08 33.8 0.6 2e-06 27.5 0.1 2.2 2 0 0 2 2 2 2 PDZ domain GRASP55_65 PF04495.14 KIY45634.1 - 7.7e-07 29.5 0.0 1.2e-06 28.9 0.0 1.4 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KIY45634.1 - 1.8e-06 28.2 0.0 3.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KIY45634.1 - 0.01 16.2 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain RICTOR_N PF14664.6 KIY45635.1 - 8.7e-121 403.4 0.9 1.2e-120 403.0 0.3 1.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KIY45635.1 - 2.8e-39 133.1 0.1 1.2e-36 124.6 0.0 3.9 2 1 2 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KIY45635.1 - 2e-38 131.1 0.1 9.3e-36 122.5 0.0 3.4 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KIY45635.1 - 3.4e-30 104.1 0.0 9.4e-28 96.3 0.0 4.3 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KIY45635.1 - 2.7e-07 30.6 4.0 7e-07 29.3 4.0 1.7 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.22 KIY45635.1 - 0.019 15.2 0.1 23 5.6 0.1 4.4 3 0 0 3 3 3 0 HEAT repeat Hemerythrin PF01814.23 KIY45636.1 - 2.9e-06 28.0 1.6 4.7e-06 27.3 1.6 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Ufd2P_core PF10408.9 KIY45637.1 - 1.1e-208 694.9 0.1 1.3e-208 694.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KIY45637.1 - 7.9e-28 96.5 0.6 3.5e-27 94.4 0.5 2.2 2 0 0 2 2 2 1 U-box domain Ribosomal_L35p PF01632.19 KIY45638.1 - 1e-16 61.2 4.9 1.1e-16 61.0 4.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 Glyco_hydro_31 PF01055.26 KIY45638.1 - 0.013 14.7 0.0 0.015 14.5 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 CwfJ_C_2 PF04676.14 KIY45639.1 - 1.3e-38 131.8 0.5 5.7e-36 123.4 0.0 2.7 2 0 0 2 2 2 2 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KIY45639.1 - 1.1e-32 112.4 0.2 1.7e-32 111.8 0.2 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CM_2 PF01817.21 KIY45640.1 - 5.1e-08 33.1 0.0 0.0022 18.3 0.0 2.6 2 0 0 2 2 2 2 Chorismate mutase type II Septin PF00735.18 KIY45641.1 - 3e-48 164.5 0.0 1.4e-18 67.2 0.0 3.2 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 KIY45641.1 - 0.00011 22.3 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY45641.1 - 0.001 18.7 0.0 0.0028 17.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIY45641.1 - 0.0042 17.5 0.2 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KIY45641.1 - 0.0092 16.0 0.2 0.94 9.5 0.1 2.4 1 1 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 KIY45641.1 - 0.031 14.5 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY45641.1 - 0.11 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 KIY45641.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein OGFr_N PF04664.13 KIY45642.1 - 5.4e-61 205.8 0.1 7e-61 205.4 0.1 1.0 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region RasGEF PF00617.19 KIY45643.1 - 4.3e-30 105.2 0.1 1.5e-29 103.5 0.1 1.9 2 0 0 2 2 2 1 RasGEF domain DUF4238 PF14022.6 KIY45644.1 - 7.8e-23 81.3 0.0 1.7e-22 80.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) His_Phos_1 PF00300.22 KIY45645.1 - 1.7e-19 70.3 2.0 9.4e-18 64.6 2.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FAD_binding_4 PF01565.23 KIY45646.1 - 7.7e-25 87.3 6.9 1.2e-24 86.6 6.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY45646.1 - 1.9e-17 63.1 0.9 3.9e-17 62.1 0.9 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KIY45646.1 - 0.061 12.7 0.3 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ATP_bind_1 PF03029.17 KIY45648.1 - 4e-74 249.4 0.0 4.9e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KIY45648.1 - 0.16 12.1 0.1 0.31 11.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain F-box PF00646.33 KIY45649.1 - 2e-08 33.9 0.5 4.5e-08 32.8 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY45649.1 - 6.4e-06 26.0 0.6 1.4e-05 24.9 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY45649.1 - 0.00023 21.0 0.1 0.00053 19.9 0.1 1.6 1 0 0 1 1 1 1 F-box FAD_binding_4 PF01565.23 KIY45651.1 - 6.7e-26 90.7 6.9 1e-25 90.1 6.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY45651.1 - 2.1e-12 46.9 2.1 3.8e-12 46.1 2.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Hyr1 PF15789.5 KIY45651.1 - 0.018 14.6 3.9 0.044 13.3 3.9 1.7 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 RasGEF PF00617.19 KIY45653.1 - 1.6e-48 165.3 0.0 3.9e-48 164.0 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY45653.1 - 4.9e-19 68.5 0.0 1.5e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.17 KIY45653.1 - 3.8e-13 48.9 0.0 7.8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY45653.1 - 4.2e-13 48.7 0.1 8e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY45653.1 - 5.8e-13 48.5 0.1 1.2e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1217 PF06748.12 KIY45653.1 - 0.037 14.1 0.0 0.26 11.3 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) Peptidase_C97 PF05903.14 KIY45654.1 - 3.6e-40 137.2 0.0 5.8e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 KIY45654.1 - 5.4e-35 121.0 0.2 9.6e-35 120.2 0.2 1.3 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 KIY45654.1 - 5.2e-15 55.3 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIY45654.1 - 7.4e-06 26.4 0.0 1.9e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KIY45654.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AAA PF00004.29 KIY45655.1 - 1.6e-39 135.4 0.0 3.3e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIY45655.1 - 4e-21 74.7 0.0 8.1e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KIY45655.1 - 4.5e-11 42.4 0.2 1e-10 41.2 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIY45655.1 - 0.00011 22.7 0.3 0.037 14.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KIY45655.1 - 0.00043 20.3 0.1 0.0032 17.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY45655.1 - 0.00057 20.0 0.9 0.0047 17.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIY45655.1 - 0.0012 19.1 0.3 0.13 12.5 0.1 2.6 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIY45655.1 - 0.0013 18.5 0.0 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIY45655.1 - 0.0067 16.6 0.1 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KIY45655.1 - 0.0086 15.5 0.8 0.11 11.9 0.3 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KIY45655.1 - 0.009 15.4 0.2 0.038 13.4 0.1 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KIY45655.1 - 0.024 14.4 0.3 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIY45655.1 - 0.057 12.6 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KIY45655.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KIY45655.1 - 0.14 11.9 0.1 0.41 10.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain XhlA PF10779.9 KIY45655.1 - 1.6 9.0 5.7 45 4.4 3.9 2.7 2 0 0 2 2 2 0 Haemolysin XhlA SQHop_cyclase_N PF13249.6 KIY45656.1 - 1.5e-106 355.7 0.8 3.3e-100 335.0 0.0 3.7 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KIY45656.1 - 1.1e-102 343.4 5.9 1.2e-97 326.9 1.7 4.1 3 2 1 4 4 4 4 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KIY45656.1 - 1.4e-18 66.3 11.1 0.0034 17.1 0.2 6.5 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KIY45656.1 - 0.0036 16.7 0.0 37 3.5 0.0 4.0 4 0 0 4 4 4 0 Pectic acid lyase TED_complement PF07678.14 KIY45656.1 - 0.031 13.3 0.5 8.7 5.3 0.0 4.3 6 0 0 6 6 6 0 A-macroglobulin TED domain RL10P_insert PF17777.1 KIY45657.1 - 6.3e-21 74.2 0.0 1.3e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KIY45657.1 - 9.7e-18 64.2 0.0 1.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 HEAT_2 PF13646.6 KIY45658.1 - 8e-30 103.1 1.5 1.7e-12 47.5 0.1 3.4 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 KIY45658.1 - 7.8e-24 81.9 1.2 0.0054 17.3 0.0 7.0 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KIY45658.1 - 2.6e-06 27.2 3.3 0.16 12.3 0.0 5.4 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.23 KIY45658.1 - 0.0011 19.0 0.0 0.2 11.8 0.0 2.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIY45658.1 - 0.069 13.7 0.7 26 5.4 0.0 3.9 3 1 0 3 3 3 0 HEAT-like repeat HNH_2 PF13391.6 KIY45659.1 - 0.096 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease NCA2 PF08637.10 KIY45660.1 - 3e-45 154.6 0.0 1e-38 133.2 0.0 3.4 2 1 1 3 3 3 3 ATP synthase regulation protein NCA2 Pkinase_fungal PF17667.1 KIY45661.1 - 4.7e-20 71.7 0.0 4.7e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KIY45661.1 - 6.2e-05 23.0 0.1 6.2e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF5521 PF17659.1 KIY45661.1 - 0.0024 15.8 1.3 0.0037 15.2 1.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5521) Pkinase PF00069.25 KIY45661.1 - 0.091 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain Peptidase_S9 PF00326.21 KIY45662.1 - 5e-48 163.4 0.3 8.2e-48 162.7 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIY45662.1 - 5.1e-07 29.6 0.3 0.0032 17.2 0.1 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold AXE1 PF05448.12 KIY45662.1 - 0.053 12.2 0.1 0.76 8.4 0.1 2.1 1 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) JmjC PF02373.22 KIY45662.1 - 0.085 13.3 0.2 5.2 7.5 0.1 2.7 2 0 0 2 2 2 0 JmjC domain, hydroxylase EF_assoc_2 PF08356.12 KIY45663.1 - 1.4e-36 124.4 0.0 2.9e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KIY45663.1 - 6.6e-32 108.9 0.2 1.7e-31 107.7 0.2 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KIY45663.1 - 1e-30 106.5 0.0 8.2e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KIY45663.1 - 9.4e-16 58.1 0.0 4.4e-09 36.6 0.0 2.7 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 KIY45663.1 - 1.3e-10 40.3 0.3 0.00076 19.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KIY45663.1 - 8.5e-10 37.5 1.6 0.00081 18.8 0.4 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KIY45663.1 - 9.5e-09 35.6 2.2 0.00057 20.3 0.1 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KIY45663.1 - 2.6e-07 29.8 4.0 0.0091 15.5 0.9 2.6 2 0 0 2 2 2 2 EF hand Arf PF00025.21 KIY45663.1 - 4.7e-07 29.4 0.0 0.0052 16.3 0.0 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY45663.1 - 7.3e-07 29.3 0.0 0.00037 20.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KIY45663.1 - 6.4e-06 26.5 0.0 0.19 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KIY45663.1 - 0.00045 20.2 0.0 0.34 10.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIY45663.1 - 0.00048 20.6 0.1 0.28 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY45663.1 - 0.00052 20.0 0.0 0.14 12.1 0.0 3.5 4 0 0 4 4 4 1 RsgA GTPase AAA_18 PF13238.6 KIY45663.1 - 0.00053 20.5 0.2 0.037 14.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY45663.1 - 0.00065 19.3 0.0 0.051 13.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KIY45663.1 - 0.00068 19.8 0.0 2.9 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KIY45663.1 - 0.0013 18.5 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KIY45663.1 - 0.0014 19.1 0.0 0.49 10.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIY45663.1 - 0.0015 18.9 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 KIY45663.1 - 0.0018 18.8 0.0 0.24 11.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter EF-hand_10 PF14788.6 KIY45663.1 - 0.0022 17.8 0.5 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 EF hand Septin PF00735.18 KIY45663.1 - 0.0043 16.4 0.0 0.036 13.3 0.0 2.0 2 0 0 2 2 2 1 Septin NB-ARC PF00931.22 KIY45663.1 - 0.005 16.1 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 KIY45663.1 - 0.0054 16.3 0.0 0.49 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIY45663.1 - 0.0054 17.0 0.2 2.7 8.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KIY45663.1 - 0.01 15.6 0.1 0.069 12.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain EF-hand_8 PF13833.6 KIY45663.1 - 0.02 14.7 0.3 2.6 8.0 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair AAA_24 PF13479.6 KIY45663.1 - 0.022 14.5 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KIY45663.1 - 0.027 14.5 0.0 5.6 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain SPARC_Ca_bdg PF10591.9 KIY45663.1 - 0.036 14.4 1.5 3.8 7.9 0.0 3.0 3 1 1 4 4 3 0 Secreted protein acidic and rich in cysteine Ca binding region Dynamin_N PF00350.23 KIY45663.1 - 0.036 14.1 0.3 3.5 7.7 0.0 2.9 2 1 1 3 3 3 0 Dynamin family Rad17 PF03215.15 KIY45663.1 - 0.036 14.0 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain MCM PF00493.23 KIY45663.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 2 0 0 2 2 1 0 MCM P-loop domain ATPase_2 PF01637.18 KIY45663.1 - 0.12 12.3 0.0 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AIG1 PF04548.16 KIY45663.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 AIG1 family ATP-synt_ab PF00006.25 KIY45663.1 - 0.14 11.7 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 KIY45663.1 - 0.15 12.0 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 KIY45663.1 - 0.16 11.4 0.0 2.5 7.5 0.0 2.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 KIY45663.1 - 0.17 11.1 0.0 0.72 9.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 KIY45663.1 - 0.18 11.5 0.1 0.42 10.3 0.1 1.6 1 0 0 1 1 1 0 Guanylate kinase Ploopntkinase3 PF18751.1 KIY45663.1 - 0.19 11.6 0.0 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DAP3 PF10236.9 KIY45663.1 - 0.23 10.6 0.0 4.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 MFS_1 PF07690.16 KIY45664.1 - 3.7e-37 128.1 52.1 3.7e-37 128.1 52.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY45664.1 - 3.2e-16 59.2 14.5 3.2e-16 59.2 14.5 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KIY45664.1 - 4 5.6 16.9 21 3.3 14.8 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NCKAP5 PF15246.6 KIY45665.1 - 0.022 14.4 7.1 0.025 14.2 7.1 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Rsbr_N PF08678.10 KIY45665.1 - 0.028 14.5 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Rsbr N terminal Caudo_TAP PF02413.17 KIY45665.1 - 0.052 13.7 8.0 0.11 12.6 8.0 1.5 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Tn7_Tnp_TnsA_C PF08721.11 KIY45665.1 - 0.14 12.8 0.5 0.14 12.8 0.5 2.6 2 1 2 4 4 4 0 TnsA endonuclease C terminal DNA_topoisoIV PF00521.20 KIY45665.1 - 0.18 10.6 5.5 0.23 10.3 5.5 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Peptidase_S46 PF10459.9 KIY45665.1 - 0.62 8.6 7.5 0.69 8.5 7.5 1.0 1 0 0 1 1 1 0 Peptidase S46 CSN5_C PF18323.1 KIY45665.1 - 2.4 9.1 5.9 7.2 7.6 5.6 2.0 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Aminotran_3 PF00202.21 KIY45666.1 - 1.3e-72 244.7 0.0 1.6e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIY45666.1 - 0.0082 15.3 0.0 0.026 13.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II NRDD PF13597.6 KIY45666.1 - 0.092 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase VWA PF00092.28 KIY45667.1 - 3.2e-10 40.5 0.0 5.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIY45667.1 - 2.4e-06 28.1 0.0 5.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DASH_Hsk3 PF08227.11 KIY45668.1 - 0.0051 17.1 0.4 0.012 16.0 0.4 1.6 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like YL1 PF05764.13 KIY45668.1 - 0.018 15.2 0.7 0.035 14.2 0.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein AAA_13 PF13166.6 KIY45668.1 - 0.028 13.1 1.3 0.04 12.6 1.3 1.1 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.11 KIY45668.1 - 0.057 13.7 0.3 1.8 8.9 0.3 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.9 KIY45668.1 - 0.11 11.4 0.9 0.2 10.6 0.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 YabA PF06156.13 KIY45668.1 - 0.59 10.8 1.6 6.1 7.5 0.4 2.3 2 0 0 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 KIY45668.1 - 0.66 10.2 8.5 2.8 8.2 1.2 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DivIVA PF05103.13 KIY45668.1 - 0.69 10.0 4.6 12 6.0 0.1 2.3 2 0 0 2 2 2 0 DivIVA protein UPF0242 PF06785.11 KIY45668.1 - 0.83 9.7 3.7 13 5.9 3.7 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 KIY45668.1 - 0.91 9.3 5.4 0.21 11.4 0.5 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH KELK PF15796.5 KIY45668.1 - 2 8.9 5.7 5.3 7.6 1.4 2.4 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DivIC PF04977.15 KIY45668.1 - 10 6.0 6.7 14 5.5 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator Pkinase_fungal PF17667.1 KIY45669.1 - 9.8e-06 24.6 5.6 0.0001 21.2 0.0 2.9 2 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KIY45669.1 - 0.054 13.4 0.1 8.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family HNH_2 PF13391.6 KIY45670.1 - 2.6e-06 27.5 0.2 5.5e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease Chromadorea_ALT PF05535.12 KIY45670.1 - 0.13 12.5 0.1 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 Chromadorea ALT protein MRP-S33 PF08293.11 KIY45671.1 - 6.5e-28 96.8 0.6 8.3e-28 96.5 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 GFO_IDH_MocA PF01408.22 KIY45672.1 - 3.2e-20 73.1 0.3 5.4e-20 72.4 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIY45672.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NCA2 PF08637.10 KIY45674.1 - 3.8e-77 259.3 0.1 8.4e-77 258.2 0.0 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 HNH_2 PF13391.6 KIY45675.1 - 4.1e-07 30.0 0.2 1e-06 28.8 0.2 1.7 1 0 0 1 1 1 1 HNH endonuclease SR-25 PF10500.9 KIY45675.1 - 0.1 12.2 4.2 0.15 11.7 4.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Phosphodiest PF01663.22 KIY45676.1 - 5.3e-79 266.4 0.4 6.4e-79 266.1 0.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KIY45676.1 - 0.00068 19.1 0.1 0.089 12.2 0.0 2.2 2 0 0 2 2 2 2 Sulfatase TFIIA_gamma_N PF02268.16 KIY45678.1 - 6.7e-24 83.7 0.1 1e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KIY45678.1 - 2.7e-21 75.4 0.1 4.2e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Glyco_transf_15 PF01793.16 KIY45679.1 - 1e-118 396.3 8.3 1.2e-118 396.1 8.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase E1_dh PF00676.20 KIY45680.1 - 8.7e-09 34.7 0.0 9.3e-09 34.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Amidohydro_2 PF04909.14 KIY45681.1 - 2.1e-13 50.7 0.1 2.6e-13 50.4 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase PKHD_C PF18331.1 KIY45681.1 - 0.12 12.5 0.4 0.28 11.3 0.4 1.7 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain Tri3 PF07428.11 KIY45682.1 - 0.0001 21.3 0.2 0.00022 20.3 0.2 1.5 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 VWA_3_C PF18571.1 KIY45682.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain CPSF73-100_C PF11718.8 KIY45682.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term AMP-binding PF00501.28 KIY45683.1 - 5.9e-26 91.0 0.1 7e-26 90.8 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIY45684.1 - 7.6e-11 41.3 0.0 9.9e-11 41.0 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KIY45684.1 - 8.9e-11 41.0 0.0 1.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIY45685.1 - 1e-35 123.3 0.0 1.2e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KIY45686.1 - 6.1e-80 268.9 0.0 1.1e-71 241.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KIY45686.1 - 4.3e-68 230.1 0.0 6.4e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KIY45686.1 - 1.4e-12 47.7 0.1 3.7e-12 46.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIY45686.1 - 5.7e-08 33.6 0.0 1.7e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_2 PF00797.17 KIY45687.1 - 5e-23 82.1 0.0 7.9e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase p450 PF00067.22 KIY45688.1 - 4.2e-59 200.5 0.0 5.7e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2754 PF10953.8 KIY45689.1 - 0.14 12.4 0.8 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) FAM194 PF14977.6 KIY45689.1 - 0.2 10.9 0.2 0.2 10.9 0.2 1.1 1 0 0 1 1 1 0 FAM194 protein Sina PF03145.16 KIY45689.1 - 2.3 8.1 5.0 12 5.8 0.3 2.3 1 1 0 2 2 2 0 Seven in absentia protein family PHD PF00628.29 KIY45691.1 - 3e-10 39.8 8.5 4.9e-10 39.2 8.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIY45691.1 - 0.0016 18.0 4.1 0.0029 17.1 4.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 KIY45691.1 - 0.025 14.6 4.2 0.056 13.5 4.2 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger zf-HC5HC2H PF13771.6 KIY45691.1 - 0.027 14.7 2.4 0.049 13.9 2.4 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 KIY45691.1 - 0.077 12.9 8.4 0.033 14.1 5.8 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.6 KIY45691.1 - 0.082 13.1 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_9 PF13901.6 KIY45691.1 - 0.2 11.6 0.9 0.31 11.0 0.9 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 KIY45691.1 - 5.1 7.1 7.6 0.46 10.4 2.9 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Complex1_LYR PF05347.15 KIY45692.1 - 3e-12 46.4 0.1 4.7e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIY45692.1 - 1.1e-05 26.1 0.2 1.7e-05 25.5 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KIY45692.1 - 0.0069 17.0 0.2 0.011 16.3 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Pro_isomerase PF00160.21 KIY45693.1 - 9.2e-11 42.3 0.1 1.8e-10 41.4 0.1 1.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.22 KIY45694.1 - 6.2e-72 242.8 0.0 8e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMO PF02461.16 KIY45694.1 - 0.089 12.6 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase F-box-like PF12937.7 KIY45695.1 - 1.5e-06 28.0 0.6 5.6e-06 26.1 0.6 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY45695.1 - 0.087 12.7 7.0 1.3 9.0 0.1 3.7 3 0 0 3 3 3 0 F-box domain Chorismate_synt PF01264.21 KIY45696.1 - 3.5e-140 466.3 0.3 4.2e-140 466.1 0.3 1.0 1 0 0 1 1 1 1 Chorismate synthase ABC_tran PF00005.27 KIY45697.1 - 1.8e-28 99.8 0.0 5.2e-28 98.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY45697.1 - 9.8e-07 28.9 1.4 0.0029 17.5 0.2 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIY45697.1 - 9.3e-06 25.6 0.0 2.2e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KIY45697.1 - 1.9e-05 24.2 0.0 0.04 13.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY45697.1 - 0.00098 19.7 0.0 0.0018 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY45697.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.20 KIY45697.1 - 0.0044 16.2 0.0 0.011 15.0 0.0 1.5 2 0 0 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 KIY45697.1 - 0.019 15.4 0.0 0.06 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 KIY45697.1 - 0.033 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIY45697.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIY45697.1 - 0.078 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 KIY45697.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase zf-C2H2 PF00096.26 KIY45699.1 - 0.0039 17.6 0.0 0.0039 17.6 0.0 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY45699.1 - 0.0086 16.8 0.1 0.0086 16.8 0.1 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger Erf4 PF10256.9 KIY45700.1 - 6.6e-19 68.1 0.2 1.1e-18 67.5 0.2 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF918 PF06033.11 KIY45700.1 - 0.22 11.5 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Glyco_hydro_115 PF15979.5 KIY45701.1 - 2.8e-127 424.8 0.0 4.2e-127 424.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KIY45701.1 - 2.2e-45 154.5 0.0 4.6e-45 153.5 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain S_layer_C PF05124.12 KIY45701.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 S-layer like family, C-terminal region CLP_protease PF00574.23 KIY45702.1 - 3.2e-75 252.0 0.0 4.1e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 Clp protease Brr6_like_C_C PF10104.9 KIY45703.1 - 3.3e-37 127.2 0.1 4.2e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Phage_holin_4_2 PF04020.13 KIY45703.1 - 0.0023 18.6 0.5 0.0073 17.0 0.1 1.8 2 0 0 2 2 2 1 Mycobacterial 4 TMS phage holin, superfamily IV COX2_TM PF02790.15 KIY45703.1 - 0.014 15.5 0.4 0.041 14.0 0.1 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain 4F5 PF04419.14 KIY45704.1 - 0.17 12.8 27.7 8.2 7.4 27.7 2.2 1 1 0 1 1 1 0 4F5 protein family DUF4778 PF16008.5 KIY45704.1 - 0.23 11.5 5.2 0.24 11.4 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) TPR_1 PF00515.28 KIY45707.1 - 2.1e-57 188.7 19.8 8.8e-08 31.7 0.0 11.2 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KIY45707.1 - 7.5e-51 166.2 19.5 0.00012 21.9 0.0 10.8 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 KIY45707.1 - 2.3e-40 133.4 6.5 7.2e-05 22.7 0.0 10.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 KIY45707.1 - 3.1e-31 107.7 8.2 1.8e-06 28.5 0.0 7.1 4 1 4 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 KIY45707.1 - 6.2e-29 98.2 11.1 0.0021 18.7 0.0 9.1 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIY45707.1 - 3.4e-27 94.5 16.4 5.9e-05 23.3 0.6 8.2 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.6 KIY45707.1 - 6e-27 92.1 9.6 0.0015 18.8 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KIY45707.1 - 4.1e-24 84.0 23.2 3e-07 30.0 0.1 9.8 7 3 4 11 11 10 6 TPR repeat TPR_19 PF14559.6 KIY45707.1 - 9.5e-22 77.3 12.6 0.0011 19.4 0.3 7.8 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 KIY45707.1 - 4e-21 74.2 10.8 0.12 13.0 0.0 9.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.6 KIY45707.1 - 4.8e-20 70.0 13.9 0.41 10.8 0.1 9.6 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 KIY45707.1 - 9.4e-17 60.9 11.5 0.004 17.3 0.1 7.1 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_15 PF13429.6 KIY45707.1 - 5.3e-10 39.0 7.8 0.037 13.3 0.1 5.8 1 1 4 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY45707.1 - 2.9e-09 37.0 11.0 0.00032 20.9 1.1 4.8 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KIY45707.1 - 3.4e-08 33.2 7.1 0.015 14.8 0.2 4.2 2 2 0 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 KIY45707.1 - 3.5e-07 30.1 8.1 0.0026 17.5 0.1 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat-like domain RPN7 PF10602.9 KIY45707.1 - 3e-05 23.8 2.1 0.37 10.5 0.2 4.9 2 2 3 5 5 5 1 26S proteasome subunit RPN7 DUF2225 PF09986.9 KIY45707.1 - 0.00077 19.3 1.8 0.63 9.7 0.0 4.2 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 KIY45707.1 - 0.0008 19.2 14.3 1.4 8.9 0.0 6.9 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 KIY45707.1 - 0.022 15.1 1.1 1.1 9.6 0.1 3.8 2 2 2 4 4 4 0 Tetratricopeptide repeat DUF5344 PF17279.2 KIY45707.1 - 0.19 12.4 0.6 1.9 9.1 0.0 2.8 3 0 0 3 3 2 0 Family of unknown function (DUF5344) ChAPs PF09295.10 KIY45707.1 - 0.25 10.3 1.1 15 4.4 0.1 2.7 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.7 KIY45707.1 - 0.29 11.2 1.2 2.4 8.2 0.0 3.0 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 KIY45707.1 - 0.32 11.1 21.2 10 6.3 0.0 6.7 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KIY45707.1 - 1.6 8.8 19.4 0.57 10.2 0.8 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Bestrophin PF01062.21 KIY45708.1 - 4e-19 69.1 2.5 8.6e-10 38.5 0.5 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel YjbT PF17089.5 KIY45708.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family bZIP_1 PF00170.21 KIY45709.1 - 7.3e-11 42.0 15.4 1.2e-10 41.3 15.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KIY45709.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 3.9 2 1 3 5 5 1 1 Transcription factor PAP1 bZIP_2 PF07716.15 KIY45709.1 - 0.0041 17.2 20.4 0.043 13.9 20.2 2.2 1 1 0 1 1 1 1 Basic region leucine zipper CCDC144C PF14915.6 KIY45709.1 - 0.0044 16.2 8.4 0.0064 15.6 8.4 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region SHE3 PF17078.5 KIY45709.1 - 0.0079 15.9 7.6 0.014 15.1 7.6 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DivIC PF04977.15 KIY45709.1 - 0.046 13.5 5.9 0.089 12.6 5.9 1.5 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.5 KIY45709.1 - 0.12 12.3 4.7 0.25 11.2 4.7 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Glutaredoxin2_C PF04399.13 KIY45709.1 - 0.22 11.4 2.4 0.38 10.6 2.4 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain YqgF PF14639.6 KIY45709.1 - 0.32 10.8 1.6 0.61 9.9 1.6 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 ABC_tran_Xtn PF12848.7 KIY45709.1 - 0.32 11.0 8.0 0.54 10.3 8.0 1.3 1 0 0 1 1 1 0 ABC transporter GvpL_GvpF PF06386.11 KIY45709.1 - 0.35 10.8 4.6 0.54 10.1 4.6 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF V_ATPase_I PF01496.19 KIY45709.1 - 0.73 7.7 4.0 1 7.2 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TSC22 PF01166.18 KIY45709.1 - 0.83 10.0 5.2 7.5 6.9 1.1 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family XhlA PF10779.9 KIY45709.1 - 1.6 9.0 5.3 2.9 8.2 5.3 1.4 1 0 0 1 1 1 0 Haemolysin XhlA DUF5094 PF17015.5 KIY45709.1 - 1.9 8.6 6.8 3.4 7.7 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Menin PF05053.13 KIY45709.1 - 8.9 4.5 10.7 14 3.9 10.7 1.2 1 0 0 1 1 1 0 Menin Reprolysin_5 PF13688.6 KIY45710.1 - 2.7e-43 148.4 5.7 2.7e-43 148.4 5.7 2.0 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KIY45710.1 - 1.3e-42 145.9 3.6 2.3e-42 145.1 3.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KIY45710.1 - 2.5e-39 135.1 2.9 4.3e-39 134.3 2.9 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KIY45710.1 - 5.5e-17 62.3 23.2 5.5e-17 62.3 23.2 4.7 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KIY45710.1 - 3e-14 53.6 0.2 7.5e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KIY45710.1 - 1.2e-07 31.8 6.8 1.2e-07 31.8 6.8 2.4 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KIY45710.1 - 0.0068 16.9 9.1 0.0068 16.9 9.1 4.9 1 1 2 3 3 3 1 ADAM cysteine-rich domain CoA_binding_3 PF13727.6 KIY45710.1 - 0.026 14.5 1.6 0.046 13.7 1.6 1.3 1 0 0 1 1 1 0 CoA-binding domain AAA PF00004.29 KIY45711.1 - 8.1e-09 36.0 0.0 2.7e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIY45711.1 - 0.23 11.7 0.3 17 5.7 0.1 2.5 1 1 0 2 2 2 0 AAA domain Mid2 PF04478.12 KIY45712.1 - 0.0036 17.1 2.0 0.0047 16.8 0.7 1.9 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF599 PF04654.12 KIY45712.1 - 0.014 14.8 6.5 0.023 14.1 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 CE2_N PF17996.1 KIY45712.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal UPF0052 PF01933.18 KIY45714.1 - 2.9e-43 148.2 0.0 3.6e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 MFS_1 PF07690.16 KIY45715.1 - 2e-31 109.2 25.4 2.9e-31 108.7 25.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY45718.1 - 5.9e-62 210.0 20.6 7.5e-62 209.7 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY45718.1 - 1e-11 44.4 27.2 1e-11 44.4 27.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Aldedh PF00171.22 KIY45719.1 - 3.1e-13 49.0 6.5 1.2e-10 40.6 3.5 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family REV PF00424.18 KIY45720.1 - 0.055 13.5 0.4 1.6 8.8 0.0 3.0 4 0 0 4 4 4 0 REV protein (anti-repression trans-activator protein) Sigma70_ner PF04546.13 KIY45722.1 - 0.024 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SR-25 PF10500.9 KIY45722.1 - 2.3 7.8 11.3 3.8 7.0 11.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 KIY45722.1 - 4.1 6.6 6.7 5.6 6.2 6.7 1.1 1 0 0 1 1 1 0 BUD22 FLYWCH_u PF16662.5 KIY45723.1 - 0.06 13.4 0.0 7.6 6.7 0.0 2.4 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 LSPR PF06049.12 KIY45723.1 - 0.15 12.0 5.7 6.5 7.0 0.1 3.1 3 0 0 3 3 3 0 Coagulation Factor V LSPD Repeat Syndecan PF01034.20 KIY45724.1 - 0.0093 15.9 0.4 0.02 14.8 0.4 1.5 1 0 0 1 1 1 1 Syndecan domain DUF456 PF04306.13 KIY45724.1 - 0.0096 16.2 0.1 0.022 15.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Yip1 PF04893.17 KIY45724.1 - 0.01 15.5 0.3 0.019 14.7 0.3 1.3 1 0 0 1 1 1 0 Yip1 domain Insulin_TMD PF17870.1 KIY45724.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4246 PF14033.6 KIY45725.1 - 3.6e-132 441.7 0.0 4.3e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Cytomega_US3 PF05963.11 KIY45725.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Cytomegalovirus US3 protein SNF2_N PF00176.23 KIY45726.1 - 6e-72 242.3 0.6 1.7e-71 240.8 0.6 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KIY45726.1 - 6.6e-21 74.2 0.3 2.3e-20 72.4 0.3 2.0 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KIY45726.1 - 9.6e-21 74.2 0.2 3.6e-18 65.9 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 KIY45726.1 - 1.2e-16 60.8 12.1 1.2e-16 60.8 12.1 2.4 2 0 0 2 2 2 1 HSA QLQ PF08880.11 KIY45726.1 - 9.2e-11 41.3 2.1 1.3e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 QLQ SnAC PF14619.6 KIY45726.1 - 2.1e-10 41.0 0.0 2.1e-10 41.0 0.0 3.8 4 1 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 KIY45726.1 - 9.2e-10 38.8 0.0 3e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KIY45726.1 - 8.8e-06 25.5 0.0 2.9e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 KIY45726.1 - 6.7e-05 22.2 0.0 0.0003 20.1 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PriA_3primeBD PF17764.1 KIY45726.1 - 0.16 11.9 0.1 0.67 9.9 0.1 2.1 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) ADH_zinc_N PF00107.26 KIY45727.1 - 6.9e-11 42.2 0.1 1.2e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY45727.1 - 1.5e-05 24.9 0.2 8.8e-05 22.4 0.2 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIY45727.1 - 0.058 13.3 0.1 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Ndc1_Nup PF09531.10 KIY45728.1 - 5.7e-80 269.7 8.7 6.5e-80 269.5 8.7 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ku PF02735.16 KIY45729.1 - 4.8e-29 101.5 0.0 8.3e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KIY45729.1 - 9.9e-20 70.9 0.0 1.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KIY45729.1 - 4.3e-06 26.6 0.0 7.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Aminotran_3 PF00202.21 KIY45730.1 - 4.9e-110 368.0 0.0 6e-110 367.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIY45730.1 - 0.0015 17.8 0.0 0.0027 16.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II SRP68 PF16969.5 KIY45731.1 - 2.4e-73 248.0 2.8 2.4e-73 248.0 2.8 2.2 2 1 0 2 2 2 1 RNA-binding signal recognition particle 68 Cation_ATPase_N PF00690.26 KIY45731.1 - 0.016 14.9 0.8 9.6 6.0 0.0 3.3 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus ANAPC3 PF12895.7 KIY45731.1 - 0.36 11.1 7.9 0.087 13.1 0.7 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ArsA_ATPase PF02374.15 KIY45732.1 - 3.7e-104 348.2 0.4 4.3e-104 348.0 0.4 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KIY45732.1 - 5.4e-09 36.2 0.1 2e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KIY45732.1 - 2.3e-06 27.7 0.0 5.4e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 KIY45732.1 - 0.002 17.8 0.1 0.053 13.1 0.0 2.3 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KIY45732.1 - 0.027 14.0 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ F-box-like PF12937.7 KIY45733.1 - 6.8e-08 32.3 0.2 2.7e-07 30.4 0.2 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY45733.1 - 0.046 13.6 0.4 0.46 10.4 0.2 2.7 2 0 0 2 2 2 0 F-box domain MIP-T3_C PF17749.1 KIY45733.1 - 0.066 13.2 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region HCV_NS4b PF01001.19 KIY45733.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b F-box-like PF12937.7 KIY45734.1 - 3.1e-08 33.4 3.3 1.2e-07 31.5 0.3 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY45734.1 - 0.0036 17.1 0.9 0.028 14.3 0.9 2.5 1 1 0 1 1 1 1 F-box domain HSP20 PF00011.21 KIY45735.1 - 6.5e-22 77.6 0.1 8.4e-22 77.3 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY45735.1 - 3.4e-09 36.1 0.0 5.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HMA PF00403.26 KIY45735.1 - 0.13 12.7 0.1 1.6 9.2 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain Oxysterol_BP PF01237.18 KIY45736.1 - 2.2e-84 283.5 0.0 4.2e-74 249.6 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Stimulus_sens_1 PF13756.6 KIY45736.1 - 0.066 13.8 0.4 0.12 12.9 0.4 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain DEAD PF00270.29 KIY45737.1 - 3.9e-47 160.3 0.0 1.8e-46 158.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY45737.1 - 1.1e-31 109.4 0.0 5e-30 104.1 0.0 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIY45737.1 - 1.7e-05 24.2 0.3 0.027 13.7 0.0 2.2 1 1 1 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KIY45737.1 - 2.5e-05 24.4 0.0 5.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIY45737.1 - 0.00031 20.2 2.2 0.0062 15.9 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Glyco_hydro_85 PF03644.13 KIY45738.1 - 1.1e-87 294.3 0.0 1.5e-87 293.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 SPRY PF00622.28 KIY45739.1 - 5.6e-20 71.7 0.1 8.9e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KIY45739.1 - 2.8e-18 66.2 0.0 5.1e-18 65.4 0.0 1.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIY45739.1 - 1.6e-05 24.7 0.4 5.3e-05 23.0 0.2 2.0 2 0 0 2 2 2 1 LisH UMP1 PF05348.11 KIY45740.1 - 3.5e-35 120.8 0.0 4.4e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 NAD_binding_8 PF13450.6 KIY45741.1 - 9.5e-12 45.0 0.0 1.2e-10 41.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY45741.1 - 0.005 16.8 0.1 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KIY45741.1 - 0.0055 16.3 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIY45741.1 - 0.0099 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY45741.1 - 0.022 14.0 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY45741.1 - 0.027 13.6 0.1 0.044 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DDOST_48kD PF03345.14 KIY45741.1 - 0.28 10.0 1.1 0.42 9.4 1.1 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta HSP20 PF00011.21 KIY45742.1 - 6.3e-22 77.7 0.1 7.7e-22 77.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY45742.1 - 2.8e-09 36.4 0.0 4.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA UPF0113_N PF17833.1 KIY45743.1 - 2.4e-30 104.9 0.0 4.1e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KIY45743.1 - 1e-26 93.0 0.0 1.6e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain NRDE-2 PF08424.10 KIY45744.1 - 2e-59 201.3 0.1 2e-59 201.3 0.1 3.3 4 0 0 4 4 4 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 KIY45744.1 - 0.002 18.6 6.4 4.6 7.8 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY45744.1 - 0.0048 17.6 18.1 0.12 13.2 0.2 6.7 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY45744.1 - 0.011 16.1 0.2 0.091 13.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat UreD PF01774.17 KIY45746.1 - 2.6e-70 236.7 0.4 3e-70 236.4 0.4 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Mito_carr PF00153.27 KIY45747.1 - 7.8e-31 105.9 6.9 5.4e-15 55.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AAA_13 PF13166.6 KIY45748.1 - 4.9 5.7 90.7 0.12 11.0 19.9 4.1 1 1 3 4 4 4 0 AAA domain Spc7 PF08317.11 KIY45748.1 - 8.1 5.2 115.6 0.14 11.0 13.4 7.0 2 1 4 6 6 6 0 Spc7 kinetochore protein His_Phos_1 PF00300.22 KIY45749.1 - 5e-36 124.2 0.1 1.3e-35 122.9 0.1 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pep3_Vps18 PF05131.14 KIY45750.1 - 3.2e-50 169.8 0.0 5.9e-50 169.0 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KIY45750.1 - 7.1e-11 42.2 4.0 1.8e-05 24.7 0.0 3.4 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KIY45750.1 - 4.8e-07 30.2 0.0 1.6e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 KIY45750.1 - 0.00032 20.6 3.2 0.00036 20.4 1.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY45750.1 - 0.066 13.6 5.2 0.048 14.0 1.5 2.3 2 0 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 KIY45750.1 - 0.071 12.9 6.2 0.067 13.0 4.5 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KIY45750.1 - 0.24 11.4 1.5 0.72 9.9 1.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger APG6_N PF17675.1 KIY45750.1 - 0.35 11.4 2.5 4.1 7.9 0.1 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-rbx1 PF12678.7 KIY45750.1 - 0.43 10.9 4.5 0.22 11.8 0.6 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIY45750.1 - 1.1 9.2 7.2 0.14 12.0 1.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY45750.1 - 1.9 8.5 5.4 0.32 10.9 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIY45750.1 - 7.4 6.3 5.0 1.2 8.8 0.9 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF2076 PF09849.9 KIY45751.1 - 0.066 13.3 20.8 0.015 15.3 17.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TRAPPC-Trs85 PF12739.7 KIY45752.1 - 2.6e-29 102.4 0.0 2.5e-27 95.9 0.0 2.4 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 KIY45752.1 - 0.055 13.6 0.1 0.34 11.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat EB1 PF03271.17 KIY45752.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 EB1-like C-terminal motif Mpv17_PMP22 PF04117.12 KIY45753.1 - 5.3e-10 39.4 2.5 5.3e-10 39.4 2.5 1.5 1 1 0 1 1 1 1 Mpv17 / PMP22 family LCCL PF03815.19 KIY45754.1 - 2e-14 53.5 0.0 3.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Seipin PF06775.14 KIY45757.1 - 2.2e-23 83.4 0.0 4e-22 79.3 0.0 2.0 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Rav1p_C PF12234.8 KIY45758.1 - 8.8e-206 685.2 0.0 1.1e-205 684.8 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal GDI PF00996.18 KIY45759.1 - 3.7e-219 727.6 0.0 4.2e-219 727.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor PhnJ PF06007.11 KIY45759.1 - 0.075 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Aldedh PF00171.22 KIY45761.1 - 7.6e-129 430.2 1.4 8.7e-129 430.0 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIY45761.1 - 0.00072 18.7 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) LMWPc PF01451.21 KIY45762.1 - 1.8e-36 125.7 0.0 2e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ADH_N PF08240.12 KIY45763.1 - 1.9e-27 95.3 3.1 3.2e-27 94.6 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY45763.1 - 2.6e-21 75.9 0.0 4.7e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY45763.1 - 3.6e-06 26.6 0.7 7.8e-06 25.5 0.7 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIY45763.1 - 5.9e-06 27.4 0.0 1.3e-05 26.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIY45763.1 - 0.00019 20.8 0.6 0.00019 20.8 0.6 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain MTCP1 PF08991.10 KIY45764.1 - 8.8e-19 67.5 1.1 9.5e-19 67.4 1.1 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type zf-RNPHF PF08080.12 KIY45764.1 - 0.026 14.5 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 RNPHF zinc finger FlbT PF07378.11 KIY45764.1 - 0.1 12.7 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Flagellar protein FlbT SH3BGR PF04908.15 KIY45765.1 - 7.2e-05 22.9 0.0 0.00014 22.0 0.0 1.6 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KIY45765.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin UQ_con PF00179.26 KIY45766.1 - 1.2e-20 73.6 0.0 2.1e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pes-10 PF07149.11 KIY45766.1 - 8.7 5.3 6.3 14 4.6 6.3 1.2 1 0 0 1 1 1 0 Pes-10 SKN1 PF03935.15 KIY45767.1 - 3e-180 599.9 10.8 1.1e-178 594.7 10.8 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 KIY45768.1 - 1.3e-184 614.3 5.4 1.5e-184 614.1 5.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SNAPc_SNAP43 PF09808.9 KIY45769.1 - 3.6e-14 53.1 0.0 4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 LAM_C PF12544.8 KIY45769.1 - 0.11 12.7 0.0 3.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Ima1_N PF09779.9 KIY45770.1 - 1.7e-31 109.9 5.0 2.6e-31 109.3 5.0 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain MrpF_PhaF PF04066.13 KIY45770.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) zinc_ribbon_10 PF10058.9 KIY45770.1 - 0.65 9.8 5.1 30 4.4 3.4 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 KIY45770.1 - 1.4 9.0 6.3 2.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon Glyco_hydro_12 PF01670.16 KIY45771.1 - 2.9e-30 105.9 12.2 3.5e-30 105.6 12.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Fasciclin PF02469.22 KIY45772.1 - 2.8e-68 228.0 0.0 1.9e-17 63.7 0.0 5.9 5 1 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.27 KIY45774.1 - 8e-67 221.2 2.2 2.7e-22 78.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NAT PF04768.13 KIY45775.1 - 1.2e-32 112.9 0.1 1.7e-19 70.2 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase TruB_C PF09142.11 KIY45775.1 - 0.0082 15.9 0.7 0.03 14.1 0.7 2.0 1 0 0 1 1 1 1 tRNA Pseudouridine synthase II, C terminal RIIa PF02197.17 KIY45775.1 - 0.087 12.5 0.0 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit adh_short PF00106.25 KIY45776.1 - 9.3e-29 100.3 0.0 1e-23 83.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY45776.1 - 4.7e-16 59.0 0.0 1.7e-14 54.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY45776.1 - 1.4e-05 25.1 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY45776.1 - 0.0035 16.8 0.2 0.0059 16.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Endomucin PF07010.12 KIY45777.1 - 0.006 16.6 52.7 0.016 15.2 52.7 1.7 1 0 0 1 1 1 1 Endomucin Macoilin PF09726.9 KIY45777.1 - 2.3 6.7 23.5 3.8 6.0 23.5 1.4 1 0 0 1 1 1 0 Macoilin family DUF4366 PF14283.6 KIY45777.1 - 4.9 7.2 18.8 2.9e+03 -1.8 18.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Pilin_N PF07790.11 KIY45778.1 - 0.049 14.6 1.4 0.16 12.9 1.4 1.9 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Thiolase_N PF00108.23 KIY45779.1 - 5.9e-72 242.2 0.2 8.5e-72 241.6 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY45779.1 - 6.4e-40 135.6 1.9 2.1e-39 134.0 1.9 1.8 1 1 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIY45779.1 - 0.0012 18.5 0.0 0.0072 15.9 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIY45779.1 - 0.0026 17.6 0.5 0.85 9.5 0.0 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KIY45779.1 - 0.02 15.0 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal APC1_C PF18122.1 KIY45780.1 - 7.8e-33 113.8 0.7 1.4e-32 112.9 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 KIY45780.1 - 2.2e-08 34.7 1.0 3e-05 24.6 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KIY45780.1 - 4e-08 33.3 0.7 0.27 11.8 0.0 4.8 4 0 0 4 4 4 3 Proteasome/cyclosome repeat TatD_DNase PF01026.21 KIY45781.1 - 5.7e-53 179.9 0.0 7.5e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 KIY45781.1 - 0.04 13.7 0.0 8.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Amidohydrolase Sec10 PF07393.11 KIY45782.1 - 1.4e-122 410.5 0.0 1.8e-122 410.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KIY45782.1 - 0.13 12.2 3.2 0.16 11.9 0.4 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KIY45782.1 - 0.15 12.0 2.2 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 F-box domain Glyco_transf_21 PF13506.6 KIY45783.1 - 8.1e-25 87.3 0.4 1.1e-19 70.5 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KIY45783.1 - 3.1e-17 63.2 0.0 4.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIY45783.1 - 1.5e-07 31.4 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 SNF2_N PF00176.23 KIY45784.1 - 6e-67 225.8 0.0 1.2e-66 224.8 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY45784.1 - 6e-14 52.3 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KIY45784.1 - 0.00015 21.7 5.2 0.00035 20.5 5.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY45784.1 - 0.05 13.5 5.3 0.14 12.0 5.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KIY45784.1 - 0.076 13.0 0.0 4 7.4 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ThrE PF06738.12 KIY45785.1 - 1.7e-44 152.1 26.0 2.6e-44 151.4 11.7 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY45785.1 - 3.5e-07 30.4 7.7 3.5e-07 30.4 7.7 2.8 3 1 0 3 3 3 2 Threonine/Serine exporter, ThrE Zn_clus PF00172.18 KIY45786.1 - 1e-06 28.8 7.5 1.7e-06 28.0 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY45786.1 - 6.4e-06 25.4 0.1 1.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sec3_C PF09763.9 KIY45788.1 - 2.7e-155 518.6 0.5 3.6e-155 518.2 0.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KIY45788.1 - 2.5e-21 75.6 0.0 5.6e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 KIY45788.1 - 0.0048 15.7 5.6 0.049 12.4 0.9 2.4 2 1 0 2 2 2 2 Vps52 / Sac2 family DUF4715 PF15835.5 KIY45788.1 - 0.14 12.2 1.1 0.33 11.0 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) Fib_alpha PF08702.10 KIY45788.1 - 1 9.5 2.8 4 7.6 2.8 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Homeodomain PF00046.29 KIY45789.1 - 0.0066 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Homeodomain Zip PF02535.22 KIY45790.1 - 1.2e-53 182.5 15.2 2e-33 116.0 3.6 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter APH PF01636.23 KIY45791.1 - 6.2e-06 26.3 0.5 1.4e-05 25.2 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY45791.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family PPR PF01535.20 KIY45791.1 - 0.13 12.6 0.0 22 5.6 0.0 2.5 2 0 0 2 2 2 0 PPR repeat Transp_cyt_pur PF02133.15 KIY45792.1 - 2.4e-103 346.3 34.2 2.8e-103 346.1 34.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aldolase_II PF00596.21 KIY45793.1 - 5e-41 140.7 0.0 6.3e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ribonucleas_3_3 PF14622.6 KIY45794.1 - 8.8e-06 25.9 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KIY45794.1 - 3.1e-05 24.6 0.1 8.8e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif SNF2_N PF00176.23 KIY45795.1 - 2.8e-54 184.2 0.1 4.3e-54 183.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY45795.1 - 5.2e-14 52.5 0.0 8.1e-13 48.7 0.1 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KIY45795.1 - 5.5e-12 45.5 3.0 2.3e-07 30.3 0.6 2.4 1 1 1 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.6 KIY45795.1 - 4.5e-05 23.1 10.3 0.00035 20.2 1.2 2.9 1 1 2 3 3 3 2 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 KIY45795.1 - 0.00016 21.7 0.2 0.001 19.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 KIY45795.1 - 0.013 15.4 8.3 0.02 14.8 0.1 3.7 4 0 0 4 4 4 0 Chromo (CHRromatin Organisation MOdifier) domain MFS_1 PF07690.16 KIY45796.1 - 1.5e-35 122.8 30.8 7.7e-35 120.5 22.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY45796.1 - 3.5e-07 29.5 23.2 0.0016 17.4 0.0 3.6 3 1 0 3 3 3 2 Sugar (and other) transporter DUF2721 PF11026.8 KIY45796.1 - 0.057 13.3 0.1 0.057 13.3 0.1 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2721) MFS_1_like PF12832.7 KIY45796.1 - 4.7 6.0 16.0 0.035 13.0 2.4 3.1 2 1 0 2 2 2 0 MFS_1 like family Complex1_LYR PF05347.15 KIY45797.1 - 0.00028 20.8 2.1 0.00054 19.9 2.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Sec8_exocyst PF04048.14 KIY45798.1 - 9.1e-30 103.4 0.1 1.8e-29 102.5 0.1 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KIY45798.1 - 0.00013 21.3 0.1 0.00053 19.4 0.1 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KIY45798.1 - 0.024 13.2 0.2 1.5 7.3 0.2 2.2 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF2451 PF10474.9 KIY45798.1 - 0.041 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) LIDHydrolase PF10230.9 KIY45799.1 - 4.8e-49 167.3 0.0 5.7e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KIY45799.1 - 1.9e-05 24.0 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY45799.1 - 0.0011 19.6 2.4 0.0011 19.6 2.4 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY45799.1 - 0.037 13.7 0.1 0.082 12.5 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold GNAT_C PF18164.1 KIY45799.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 GNAT-like C-terminal domain PUF PF00806.19 KIY45800.1 - 4.1e-24 82.8 0.1 7.2e-06 25.4 0.0 5.8 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat DUF900 PF05990.12 KIY45800.1 - 0.12 11.8 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) MMR_HSR1 PF01926.23 KIY45801.1 - 2.1e-15 56.8 0.0 9.9e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY45801.1 - 2.4e-06 27.6 0.0 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIY45801.1 - 5.9e-06 25.9 0.0 4.1e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KIY45801.1 - 0.00043 19.7 0.1 0.00089 18.6 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIY45801.1 - 0.036 14.1 0.1 0.084 12.9 0.1 1.6 1 0 0 1 1 1 0 Dynamin family CBM_20 PF00686.19 KIY45802.1 - 3.6e-26 90.9 0.0 1.1e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 KIY45802.1 - 4.2e-13 49.6 0.0 6.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIY45802.1 - 1.2e-09 38.5 0.1 3e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Pkinase PF00069.25 KIY45803.1 - 7.5e-46 156.6 0.0 9.3e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45803.1 - 6.4e-30 104.3 0.0 7.8e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIY45803.1 - 2.7e-05 24.4 0.0 6.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 KIY45803.1 - 0.039 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGAP1 PF07819.13 KIY45804.1 - 9.3e-08 32.1 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KIY45804.1 - 9e-05 22.4 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KIY45804.1 - 0.00028 21.6 0.4 0.00028 21.6 0.4 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY45804.1 - 0.0023 17.7 0.1 0.0078 15.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 KIY45804.1 - 0.023 14.2 0.2 0.044 13.3 0.1 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF915 PF06028.11 KIY45804.1 - 0.028 13.7 0.0 0.19 11.0 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 KIY45804.1 - 0.07 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIY45804.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 KIY45804.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) p450 PF00067.22 KIY45805.1 - 1.4e-22 80.1 0.0 8e-22 77.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KIY45806.1 - 2.8e-15 56.1 1.9 1.2e-13 50.7 1.9 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain E3_UbLigase_R4 PF13764.6 KIY45806.1 - 0.089 10.9 0.2 0.12 10.5 0.2 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 RNA_pol_Rpb1_1 PF04997.12 KIY45807.1 - 2.2e-108 362.3 0.0 3e-108 361.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KIY45807.1 - 3.7e-105 351.1 0.0 5.3e-105 350.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIY45807.1 - 8e-74 247.4 0.0 1.3e-73 246.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KIY45807.1 - 1.2e-59 201.4 0.0 2.2e-59 200.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KIY45807.1 - 1.3e-50 171.4 0.0 5e-50 169.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KIY45807.1 - 1.9e-48 163.9 0.2 4e-48 162.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KIY45807.1 - 5.3e-35 119.6 0.0 1.1e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KIY45807.1 - 9e-05 22.6 117.8 0.019 15.3 10.1 9.6 3 2 9 13 13 13 10 RNA polymerase Rpb1 C-terminal repeat Herpes_BLLF1 PF05109.13 KIY45807.1 - 3 5.7 25.4 4.9 5.0 25.4 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) PS_Dcarbxylase PF02666.15 KIY45808.1 - 4.7e-71 238.5 0.0 3.5e-69 232.4 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 KIY45808.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit DUF4642 PF15484.6 KIY45809.1 - 0.45 10.7 11.0 2.7 8.2 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4642) RNA_pol_Rpb5_C PF01191.19 KIY45810.1 - 0.096 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Pkinase PF00069.25 KIY45811.1 - 3e-53 180.9 0.0 3.5e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45811.1 - 3.5e-20 72.4 0.0 4.8e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY45811.1 - 1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY45811.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY45811.1 - 0.076 12.9 0.1 5.5 6.8 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family TB2_DP1_HVA22 PF03134.19 KIY45812.1 - 6e-25 87.0 10.1 6e-25 87.0 10.1 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family FtsX PF02687.21 KIY45812.1 - 0.041 14.4 3.4 0.07 13.6 3.4 1.4 1 0 0 1 1 1 0 FtsX-like permease family Ost5 PF05251.12 KIY45813.1 - 3.2e-19 68.9 12.1 4e-19 68.6 12.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 RNA_pol_Rpb2_4 PF04566.13 KIY45815.1 - 0.18 12.1 0.0 0.21 11.9 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 zf-CCHC PF00098.23 KIY45816.1 - 4.2e-07 29.7 2.7 1.1e-06 28.5 2.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIY45816.1 - 0.0042 16.8 1.4 0.0095 15.6 1.4 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger tRNA-Thr_ED PF08915.11 KIY45816.1 - 0.022 14.8 0.1 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase zf-CCHC_3 PF13917.6 KIY45816.1 - 0.15 12.1 1.5 0.54 10.3 0.9 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIY45816.1 - 0.29 11.0 1.0 0.88 9.5 1.0 1.9 1 0 0 1 1 1 0 Zinc knuckle Shikimate_dh_N PF08501.11 KIY45820.1 - 0.028 14.7 0.0 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain HMG_box PF00505.19 KIY45820.1 - 0.093 13.2 2.0 0.27 11.7 0.9 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY45820.1 - 0.77 10.4 3.9 0.53 10.9 0.4 2.4 2 0 0 2 2 2 0 HMG-box domain Pet127 PF08634.10 KIY45821.1 - 0.036 13.5 0.1 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet127 gag-asp_proteas PF13975.6 KIY45824.1 - 0.00014 22.4 0.0 0.00043 20.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 KIY45824.1 - 0.001 18.9 3.0 0.0028 17.4 3.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY45824.1 - 0.0021 18.1 6.1 0.005 16.9 6.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Clr5 PF14420.6 KIY45824.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Clr5 domain Asp_protease_2 PF13650.6 KIY45824.1 - 0.033 14.8 0.0 0.076 13.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Retrotran_gag_2 PF14223.6 KIY45825.1 - 2.7e-12 46.5 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF5601 PF18151.1 KIY45825.1 - 0.041 14.2 0.1 0.24 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) SAP30_Sin3_bdg PF13867.6 KIY45825.1 - 0.13 12.6 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF5349 PF17298.2 KIY45825.1 - 1.3 8.7 4.8 2 8.1 4.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Iso_dh PF00180.20 KIY45827.1 - 1e-97 327.4 0.0 1.2e-97 327.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.25 KIY45828.1 - 1.4e-05 24.6 0.0 0.0016 17.8 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY45828.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase ResIII PF04851.15 KIY45830.1 - 5.7e-23 81.8 0.0 2.5e-22 79.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY45830.1 - 8.1e-17 61.6 0.0 2.1e-15 57.0 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY45830.1 - 8.1e-15 55.0 0.0 1.8e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KIY45830.1 - 4.8e-06 25.5 0.0 9.4e-06 24.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.9 KIY45830.1 - 1.5e-05 24.4 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 KIY45830.1 - 0.00014 21.1 0.0 0.00031 20.1 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KIY45830.1 - 0.0081 16.4 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KIY45830.1 - 0.028 14.0 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD_2 PF06733.15 KIY45830.1 - 0.25 11.0 0.7 0.4 10.3 0.0 1.6 2 0 0 2 2 2 0 DEAD_2 Leu_zip PF15294.6 KIY45831.1 - 0.0014 18.2 0.2 0.0019 17.8 0.2 1.1 1 0 0 1 1 1 1 Leucine zipper CHASE3 PF05227.13 KIY45831.1 - 0.018 14.9 3.9 0.17 11.8 1.0 2.3 1 1 1 2 2 2 0 CHASE3 domain DUF4164 PF13747.6 KIY45831.1 - 0.021 15.1 1.9 0.021 15.1 1.9 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) MAD PF05557.13 KIY45831.1 - 0.023 13.1 2.5 0.045 12.1 2.2 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Rhamno_transf PF11316.8 KIY45831.1 - 0.036 13.5 2.9 0.058 12.8 2.9 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase ATG16 PF08614.11 KIY45831.1 - 0.067 13.4 7.1 0.73 10.0 1.0 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KIY45831.1 - 0.1 12.3 6.1 0.74 9.4 6.1 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4140 PF13600.6 KIY45831.1 - 0.14 12.6 2.2 6 7.4 0.0 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 KIY45831.1 - 0.68 10.2 4.3 7 6.9 1.7 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 KIY45831.1 - 7.7 4.9 11.5 1.7 7.1 6.7 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family GAS2 PF02187.17 KIY45832.1 - 2.9e-12 46.5 0.0 9.2e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain PCMT PF01135.19 KIY45833.1 - 3.9e-63 213.0 0.0 4.7e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KIY45833.1 - 4.2e-08 33.1 0.0 8.9e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY45833.1 - 2e-05 25.2 0.0 3.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KIY45833.1 - 0.00021 21.3 0.0 0.00032 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY45833.1 - 0.00034 20.5 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY45833.1 - 0.00057 20.5 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY45833.1 - 0.0024 17.2 0.0 0.0035 16.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KIY45833.1 - 0.0077 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 KIY45833.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIY45833.1 - 0.028 14.0 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 KIY45833.1 - 0.037 13.8 0.0 0.061 13.1 0.0 1.5 1 1 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.7 KIY45833.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1799 PF08809.11 KIY45834.1 - 0.01 16.0 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 1 Phage related hypothetical protein (DUF1799) Lzipper-MIP1 PF14389.6 KIY45834.1 - 0.016 15.5 0.9 0.82 10.0 0.1 2.1 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1153 PF06627.11 KIY45834.1 - 0.12 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) Myb_DNA-binding PF00249.31 KIY45835.1 - 8.4e-42 141.1 8.5 1.9e-14 53.6 0.3 5.1 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY45835.1 - 1.7e-31 108.2 0.7 4.2e-09 36.5 0.0 5.1 3 2 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIY45835.1 - 3.7e-05 23.5 1.1 0.019 14.8 0.0 3.1 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 KIY45835.1 - 0.00087 19.3 0.0 0.5 10.4 0.0 3.2 1 1 2 3 3 3 1 SLIDE DUF3606 PF12244.8 KIY45835.1 - 0.0014 18.5 2.4 0.39 10.7 0.3 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3606) ERp29 PF07749.12 KIY45835.1 - 0.0063 17.4 1.0 1.6 9.7 0.0 3.1 3 0 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain SANT_DAMP1_like PF16282.5 KIY45835.1 - 0.02 15.1 5.9 8.2 6.7 0.1 3.4 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 TAF8_C PF10406.9 KIY45837.1 - 1.1e-12 48.3 2.7 2.6e-12 47.1 2.7 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KIY45837.1 - 0.0011 18.9 0.1 0.0019 18.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated TMEM208_SND2 PF05620.11 KIY45838.1 - 8.7e-51 172.0 0.0 9.9e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Flavokinase PF01687.17 KIY45841.1 - 1.5e-32 112.2 0.0 2e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_S11 PF00411.19 KIY45842.1 - 1.6e-12 47.8 0.0 2.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L5e PF17144.4 KIY45842.1 - 0.07 13.1 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 GNAT_C PF18164.1 KIY45843.1 - 0.19 11.4 0.1 0.26 11.0 0.1 1.2 1 0 0 1 1 1 0 GNAT-like C-terminal domain MHYT PF03707.16 KIY45844.1 - 7.1 6.9 11.8 4.6 7.5 7.2 2.7 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat UCR_UQCRX_QCR9 PF05365.12 KIY45845.1 - 3.1e-26 91.0 1.6 3.4e-26 90.9 1.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RRM_1 PF00076.22 KIY45846.1 - 2.2e-13 49.8 0.0 2.5e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY45846.1 - 5e-06 26.1 0.0 6.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY45846.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif DUF561 PF04481.12 KIY45846.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Diphthamide_syn PF01866.17 KIY45847.1 - 6.3e-98 327.9 0.0 3.5e-59 200.7 0.0 2.2 2 0 0 2 2 2 2 Putative diphthamide synthesis protein NPC1_N PF16414.5 KIY45848.1 - 3.7e-81 272.3 6.8 3.7e-81 272.3 6.8 1.8 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Patched PF02460.18 KIY45848.1 - 9.7e-66 222.4 0.8 1.1e-33 116.3 0.1 3.0 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 KIY45848.1 - 1.4e-44 151.6 18.1 1.2e-23 83.6 0.2 3.5 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KIY45848.1 - 0.00011 20.0 6.3 0.00018 19.3 6.3 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Folate_rec PF03024.14 KIY45848.1 - 0.0014 18.6 1.2 0.003 17.5 1.2 1.5 1 0 0 1 1 1 1 Folate receptor family GPR15L PF15854.5 KIY45848.1 - 0.071 13.4 0.3 0.24 11.7 0.3 1.9 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 SET PF00856.28 KIY45849.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 SET domain Aminotran_3 PF00202.21 KIY45850.1 - 4.9e-101 338.3 0.0 6.7e-101 337.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIY45850.1 - 0.00058 19.1 0.0 0.00097 18.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 KIY45851.1 - 1.4e-77 261.3 0.0 1.9e-77 260.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIY45851.1 - 1.6e-05 23.6 0.0 2.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIY45851.1 - 0.0004 19.5 0.0 0.00085 18.4 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Pertussis_S1 PF02917.14 KIY45851.1 - 0.0052 16.6 0.4 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 Pertussis toxin, subunit 1 Cyto_heme_lyase PF01265.17 KIY45851.1 - 0.23 11.0 0.8 0.44 10.1 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase FAD_binding_6 PF00970.24 KIY45852.1 - 2.6e-08 34.1 0.0 5.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIY45852.1 - 0.0022 18.2 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KIY45852.1 - 0.0044 17.6 0.0 0.0093 16.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain XRN_N PF03159.18 KIY45855.1 - 6.4e-28 97.8 0.0 7.8e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus IF-2B PF01008.17 KIY45856.1 - 2.2e-78 263.3 0.0 3.3e-78 262.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF3839 PF12943.7 KIY45856.1 - 0.073 12.5 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) DUF3402 PF11882.8 KIY45857.1 - 6.9e-105 351.8 2.5 6.9e-105 351.8 2.5 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KIY45857.1 - 2e-37 129.0 0.1 4.2e-35 121.3 0.0 2.4 1 1 1 2 2 2 2 N1221-like protein MT-A70 PF05063.14 KIY45858.1 - 1.7e-56 190.8 0.1 2.3e-56 190.4 0.1 1.2 1 0 0 1 1 1 1 MT-A70 ACBP PF00887.19 KIY45859.1 - 2.3e-17 63.0 0.0 3.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein GMC_oxred_N PF00732.19 KIY45860.1 - 7.4e-47 160.1 0.0 9.6e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY45860.1 - 6.3e-31 107.8 0.0 1.2e-30 106.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY45860.1 - 0.0028 17.9 0.1 0.0084 16.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIY45860.1 - 0.006 15.7 0.1 0.12 11.4 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Aldo_ket_red PF00248.21 KIY45861.1 - 2.1e-14 53.4 0.0 2.1e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Vfa1 PF08432.10 KIY45863.1 - 7.5e-38 130.7 5.5 8.4e-38 130.5 5.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SRP-alpha_N PF04086.13 KIY45863.1 - 0.019 14.9 6.1 0.022 14.7 6.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF5023 PF16426.5 KIY45863.1 - 0.026 14.2 0.3 0.036 13.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5023) DUF3987 PF13148.6 KIY45863.1 - 0.04 12.9 1.5 0.052 12.6 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Spt20 PF12090.8 KIY45863.1 - 0.063 12.9 4.3 0.077 12.6 4.3 1.2 1 0 0 1 1 1 0 Spt20 family Hydin_ADK PF17213.3 KIY45863.1 - 0.21 11.8 1.8 0.28 11.4 1.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RR_TM4-6 PF06459.12 KIY45863.1 - 0.22 11.3 4.2 0.25 11.1 4.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.14 KIY45863.1 - 0.23 11.2 1.6 0.33 10.7 1.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NARP1 PF12569.8 KIY45863.1 - 0.24 10.2 4.0 0.31 9.9 4.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FancD2 PF14631.6 KIY45863.1 - 0.48 7.8 2.2 0.52 7.6 2.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease MSA-2c PF12238.8 KIY45863.1 - 1.7 8.6 9.2 2.1 8.3 9.2 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Presenilin PF01080.17 KIY45863.1 - 7 5.3 5.3 8.6 5.0 5.3 1.1 1 0 0 1 1 1 0 Presenilin ADH_N PF08240.12 KIY45864.1 - 7e-24 83.8 1.8 1.4e-23 82.9 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY45864.1 - 3.4e-19 69.1 0.4 7.9e-19 67.9 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIY45864.1 - 0.013 14.8 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KIY45864.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 KIY45864.1 - 0.019 14.3 1.2 0.058 12.7 0.9 1.9 2 0 0 2 2 2 0 ThiF family MFS_1 PF07690.16 KIY45865.1 - 5e-27 94.7 49.1 2.1e-26 92.7 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY45865.1 - 1.1e-06 27.8 1.7 1.1e-06 27.8 1.7 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter Chromate_transp PF02417.15 KIY45865.1 - 0.029 14.5 18.1 0.046 13.9 12.6 3.3 2 1 0 2 2 2 0 Chromate transporter Peptidase_M43 PF05572.13 KIY45866.1 - 2.8e-15 56.6 0.1 6e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KIY45866.1 - 3.8e-05 23.9 0.2 6.4e-05 23.2 0.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KIY45866.1 - 0.00015 22.3 0.0 0.00033 21.1 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 KIY45866.1 - 0.0014 18.8 0.6 0.0026 17.9 0.6 1.5 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.6 KIY45866.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KIY45866.1 - 0.047 13.5 0.0 0.068 13.0 0.0 1.4 1 1 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 KIY45866.1 - 0.09 12.7 0.4 0.29 11.0 0.2 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KIY45866.1 - 0.16 10.9 2.2 0.18 10.8 1.1 1.5 2 0 0 2 2 2 0 Peptidase M66 Glu-tRNAGln PF02686.15 KIY45867.1 - 0.0011 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit MRP-S34 PF16053.5 KIY45868.1 - 2.3e-08 33.7 0.3 3e-08 33.4 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Methyltransf_16 PF10294.9 KIY45870.1 - 1.5e-45 155.1 0.0 1.9e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KIY45870.1 - 0.00066 19.2 0.0 0.00091 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIY45870.1 - 0.0064 16.1 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIY45870.1 - 0.047 14.4 0.0 0.083 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIY45870.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain BolA PF01722.18 KIY45871.1 - 8.3e-13 48.4 0.0 1.5e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein Stb3 PF10330.9 KIY45871.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative Sin3 binding protein COX15-CtaA PF02628.15 KIY45872.1 - 2.7e-109 365.2 9.5 3.3e-109 364.9 9.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Proteasome PF00227.26 KIY45873.1 - 3.3e-54 183.3 0.0 4e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY45873.1 - 6.6e-13 48.1 0.1 1.1e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Prok-RING_1 PF14446.6 KIY45874.1 - 0.0005 19.9 5.4 0.0012 18.7 0.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DZR PF12773.7 KIY45874.1 - 0.017 15.1 1.3 0.023 14.7 0.5 1.7 2 0 0 2 2 2 0 Double zinc ribbon CxC3 PF18804.1 KIY45874.1 - 0.041 13.7 0.4 0.067 13.0 0.4 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Peroxidase_2 PF01328.17 KIY45875.1 - 1.3e-38 133.5 0.0 1.7e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 MTP18 PF10558.9 KIY45878.1 - 2e-62 210.2 8.1 4.8e-61 205.7 8.1 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-HIT PF04438.16 KIY45879.1 - 5.2e-07 29.4 12.3 8.1e-07 28.8 12.3 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KIY45879.1 - 0.041 14.0 6.5 0.041 14.0 6.5 1.5 1 1 0 1 1 1 0 MYND finger TPR_1 PF00515.28 KIY45880.1 - 2e-09 36.8 2.9 0.016 15.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY45880.1 - 2.7e-08 33.3 2.5 0.073 13.2 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY45880.1 - 0.00067 19.7 0.3 0.57 10.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY45880.1 - 0.0011 18.9 1.7 0.0051 16.9 0.2 2.6 2 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 KIY45880.1 - 0.0015 19.0 0.2 0.11 13.0 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY45880.1 - 0.0081 16.9 0.5 1.2 10.2 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY45880.1 - 0.022 14.8 0.4 6.8 7.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CO_deh_flav_C PF03450.17 KIY45880.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Cyclin PF08613.11 KIY45881.1 - 6.3e-05 23.4 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin BTB PF00651.31 KIY45882.1 - 0.00036 20.7 0.0 0.00065 19.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Cactin_mid PF10312.9 KIY45883.1 - 1.9e-65 220.3 5.1 1.9e-65 220.3 5.1 2.4 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KIY45883.1 - 5.2e-60 200.9 7.2 9.3e-60 200.1 7.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1181 PF06680.11 KIY45883.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) HMG_box PF00505.19 KIY45884.1 - 0.00037 20.9 0.1 0.13 12.6 0.0 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY45884.1 - 0.013 16.1 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 HMG-box domain Ndr PF03096.14 KIY45884.1 - 0.1 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family AAA_2 PF07724.14 KIY45885.1 - 1.7e-33 116.2 0.0 2.5e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KIY45885.1 - 2.5e-10 40.9 0.0 4.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIY45885.1 - 3e-06 27.2 0.0 5.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Ran_BP1 PF00638.18 KIY45886.1 - 4.6e-50 169.0 0.6 7.1e-50 168.4 0.6 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KIY45886.1 - 4.3e-05 23.4 0.3 0.0003 20.7 0.3 2.0 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 KIY45886.1 - 0.0003 20.5 0.1 0.00036 20.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CK2S PF15011.6 KIY45886.1 - 0.025 14.5 0.1 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate EMP24_GP25L PF01105.24 KIY45887.1 - 1.2e-48 165.5 0.0 1.5e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SNF2_N PF00176.23 KIY45888.1 - 3.5e-49 167.4 0.0 8.2e-49 166.2 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY45888.1 - 9e-20 71.1 0.0 3.2e-18 66.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KIY45888.1 - 0.00061 19.1 0.0 0.003 16.8 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KIY45888.1 - 0.021 14.0 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PHD PF00628.29 KIY45888.1 - 0.067 13.1 21.0 0.053 13.4 11.2 3.0 2 1 1 3 3 3 0 PHD-finger Amidohydro_2 PF04909.14 KIY45889.1 - 2e-08 34.4 0.0 3.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KIY45889.1 - 0.00059 19.2 0.0 0.0016 17.8 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Kinesin PF00225.23 KIY45890.1 - 6.5e-110 367.2 0.0 1.4e-109 366.1 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY45890.1 - 1.6e-25 89.8 0.0 3.1e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding TruD PF01142.18 KIY45890.1 - 0.003 16.4 1.3 0.0058 15.5 1.3 1.4 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) ThiF PF00899.21 KIY45891.1 - 3.1e-105 350.9 0.0 7.4e-70 235.1 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KIY45891.1 - 2.4e-89 299.6 0.0 4.4e-89 298.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KIY45891.1 - 4.5e-35 119.7 0.0 1e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KIY45891.1 - 1.5e-28 99.3 0.1 6e-28 97.4 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KIY45891.1 - 5.8e-26 90.5 1.1 1.4e-25 89.3 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle IPK PF03770.16 KIY45892.1 - 1e-47 162.6 0.0 1.3e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase DAO PF01266.24 KIY45893.1 - 4.7e-38 131.7 0.0 5.5e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY45893.1 - 8.3e-05 22.0 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KIY45893.1 - 0.0027 17.2 0.1 0.05 13.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GIDA PF01134.22 KIY45893.1 - 0.0079 15.3 0.0 0.34 10.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIY45893.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain KR PF08659.10 KIY45893.1 - 0.032 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 KR domain DUF2156 PF09924.9 KIY45893.1 - 0.034 13.2 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2156) ThiF PF00899.21 KIY45893.1 - 0.053 12.9 0.2 0.097 12.0 0.2 1.3 1 0 0 1 1 1 0 ThiF family Ldh_1_N PF00056.23 KIY45893.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KIY45893.1 - 0.073 13.1 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding adh_short PF00106.25 KIY45893.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase dUTPase PF00692.19 KIY45894.1 - 1e-40 138.4 0.0 1.2e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 dUTPase Forkhead PF00250.18 KIY45895.1 - 1e-25 89.8 0.0 2e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KIY45895.1 - 1.4e-06 28.5 0.0 2.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Forkhead PF00250.18 KIY45896.1 - 4.9e-31 106.8 0.0 7.7e-31 106.2 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Rubella_Capsid PF05750.11 KIY45896.1 - 0.0046 16.6 6.2 0.0046 16.6 6.2 2.0 1 1 0 2 2 2 1 Rubella capsid protein CAP_N PF01213.19 KIY45896.1 - 0.014 14.9 2.2 0.014 14.9 2.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal CIAPIN1 PF05093.13 KIY45897.1 - 1.3e-32 112.3 3.8 2.3e-32 111.5 3.8 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KIY45897.1 - 5.2e-08 33.2 0.1 8e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus DUF4646 PF15496.6 KIY45898.1 - 1.4e-07 32.2 0.6 0.0011 19.6 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4646) Rrn6 PF10214.9 KIY45898.1 - 0.12 10.9 14.4 0.098 11.1 2.7 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 KIY45898.1 - 0.61 8.3 15.5 0.0095 14.3 5.7 2.0 2 0 0 2 2 2 0 CDC45-like protein Longin PF13774.6 KIY45899.1 - 1.6e-25 88.9 0.1 2.6e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KIY45899.1 - 2.7e-15 55.9 0.1 4.4e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Nab1 PF04902.12 KIY45899.1 - 0.08 13.3 0.3 0.15 12.4 0.3 1.4 1 0 0 1 1 1 0 Conserved region in Nab1 DUF962 PF06127.11 KIY45900.1 - 4.6e-21 74.7 6.9 3.1e-20 72.0 6.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Glyco_transf_18 PF15024.6 KIY45901.1 - 1.5e-08 33.8 0.0 2.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 adh_short_C2 PF13561.6 KIY45902.1 - 3.1e-65 220.0 1.6 3.8e-65 219.7 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY45902.1 - 2e-47 161.2 0.9 2.5e-47 160.9 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY45902.1 - 1.2e-06 28.5 1.4 1.7e-06 28.0 0.4 1.6 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KIY45902.1 - 0.0015 18.4 0.6 0.0084 16.0 0.7 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S7e PF01251.18 KIY45903.1 - 7.3e-84 280.1 2.2 8.4e-84 279.9 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e MRC1 PF09444.10 KIY45904.1 - 2.9e-20 73.3 19.5 2.9e-20 73.3 19.5 6.9 7 2 0 7 7 7 1 MRC1-like domain EAGR_box PF16713.5 KIY45906.1 - 0.18 11.5 1.8 9 6.1 0.8 2.2 2 0 0 2 2 2 0 Enriched in aromatic and glycine Residues box Ras PF00071.22 KIY45907.1 - 3.5e-44 150.3 0.0 2.5e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KIY45907.1 - 1.5e-30 105.9 0.0 2.2e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY45907.1 - 6.5e-12 45.2 0.0 1.5e-11 44.1 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY45907.1 - 4.6e-06 26.7 0.0 1.1e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY45907.1 - 0.00014 21.3 0.0 0.00092 18.6 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KIY45907.1 - 0.002 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KIY45907.1 - 0.0022 17.9 0.4 0.013 15.4 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KIY45907.1 - 0.0074 16.0 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KIY45907.1 - 0.011 16.0 0.1 0.045 14.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIY45907.1 - 0.012 16.0 0.0 0.035 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KIY45907.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain BUD22 PF09073.10 KIY45907.1 - 0.41 9.9 3.1 0.52 9.6 3.1 1.1 1 0 0 1 1 1 0 BUD22 PPR_2 PF13041.6 KIY45908.1 - 2.5e-08 34.0 0.2 0.26 11.5 0.0 5.1 5 1 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KIY45908.1 - 0.00022 21.3 0.0 0.26 11.4 0.0 3.7 3 1 0 4 4 4 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIY45908.1 - 0.00032 20.3 5.0 0.28 10.9 0.0 3.6 4 0 0 4 4 4 2 PPR repeat PPR PF01535.20 KIY45908.1 - 0.00033 20.7 0.2 4.1 7.9 0.0 4.6 4 0 0 4 4 4 1 PPR repeat AMMECR1 PF01871.17 KIY45909.1 - 1.6e-47 161.2 0.0 2.1e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Ribosomal_L3 PF00297.22 KIY45910.1 - 2.1e-183 609.4 8.1 2.6e-183 609.1 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Pex2_Pex12 PF04757.14 KIY45911.1 - 2.3e-47 161.5 4.1 2.7e-47 161.2 4.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KIY45911.1 - 5e-06 26.3 2.7 7.4e-06 25.7 2.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY45911.1 - 0.00012 21.9 5.6 0.00018 21.3 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY45911.1 - 0.00065 19.8 7.2 0.0011 19.1 7.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIY45911.1 - 0.0066 16.4 6.6 0.012 15.6 6.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY45911.1 - 0.02 15.2 3.5 0.032 14.6 3.5 1.3 1 0 0 1 1 1 0 Ring finger domain Bromodomain PF00439.25 KIY45911.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Bromodomain zf-C3HC4 PF00097.25 KIY45911.1 - 0.2 11.6 4.8 0.31 10.9 4.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-piccolo PF05715.13 KIY45911.1 - 0.22 11.7 2.9 0.35 11.0 2.9 1.3 1 0 0 1 1 1 0 Piccolo Zn-finger Prok-RING_4 PF14447.6 KIY45911.1 - 0.29 11.0 4.4 0.48 10.3 0.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 KIY45911.1 - 1.1 9.2 3.4 7 6.6 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.6 KIY45911.1 - 3.5 7.7 6.2 8.5 6.4 6.3 1.5 1 1 0 1 1 1 0 zinc-RING finger domain Haem_degrading PF03928.14 KIY45912.1 - 0.00025 21.1 0.0 0.00066 19.7 0.0 1.7 1 1 0 1 1 1 1 Haem-degrading SSB PF00436.25 KIY45913.1 - 4e-17 62.1 0.0 5.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GTP_EFTU PF00009.27 KIY45914.1 - 5e-44 150.2 0.0 1.1e-43 149.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KIY45914.1 - 1.5e-16 60.4 1.3 2.3e-15 56.6 1.7 2.3 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KIY45914.1 - 2e-11 44.2 0.0 1.4e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KIY45914.1 - 2.3e-07 30.9 0.0 4.7e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIY45914.1 - 1.3e-05 25.4 0.7 3.8e-05 24.0 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 KIY45914.1 - 0.022 15.0 0.0 7.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIY45914.1 - 0.035 14.0 0.3 1.1 9.1 0.1 2.5 2 1 0 2 2 2 0 RsgA GTPase Ras PF00071.22 KIY45914.1 - 0.039 13.6 0.0 0.92 9.1 0.0 2.3 2 0 0 2 2 2 0 Ras family SRPRB PF09439.10 KIY45914.1 - 0.087 12.2 0.0 4.2 6.7 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.21 KIY45914.1 - 0.089 12.2 0.5 3.4 7.1 0.0 2.7 2 1 1 3 3 3 0 ADP-ribosylation factor family AMPK1_CBM PF16561.5 KIY45915.1 - 2.5e-19 69.3 0.1 3e-19 69.0 0.1 1.0 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 KIY45915.1 - 0.0061 17.1 0.1 0.0077 16.8 0.1 1.2 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DAO PF01266.24 KIY45916.1 - 2.2e-52 178.8 0.0 2.5e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY45916.1 - 0.0023 18.1 0.1 0.0081 16.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Semialdhyde_dh PF01118.24 KIY45916.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Mqo PF06039.15 KIY45916.1 - 0.04 12.5 0.0 0.29 9.6 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GMC_oxred_N PF00732.19 KIY45916.1 - 0.056 12.8 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase NDUFA12 PF05071.16 KIY45917.1 - 7.2e-33 113.3 3.0 9.5e-33 112.9 3.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 2-oxogl_dehyd_N PF16078.5 KIY45917.1 - 0.058 13.0 2.0 1.8 8.2 0.7 2.7 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus WD40 PF00400.32 KIY45918.1 - 1.4e-44 149.2 23.7 1.7e-08 35.0 0.6 8.7 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KIY45918.1 - 4.8e-12 45.6 0.3 1.1e-11 44.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY45918.1 - 1.3e-10 40.8 0.3 3.5e-10 39.5 0.3 1.8 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KIY45918.1 - 7.3e-08 32.6 0.5 1.1 9.6 0.1 5.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY45918.1 - 3.9e-07 29.1 14.1 0.32 9.6 0.1 6.1 2 2 5 7 7 7 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KIY45918.1 - 0.0027 17.7 0.2 31 4.6 0.0 4.8 4 2 1 6 6 6 0 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 KIY45918.1 - 0.02 14.8 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 F-box PALB2_WD40 PF16756.5 KIY45918.1 - 0.098 11.6 0.7 53 2.6 0.0 4.1 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain LEAP-2 PF07359.11 KIY45918.1 - 0.14 12.0 7.4 0.17 11.8 4.1 2.5 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Glyco_hydro_88 PF07470.13 KIY45919.1 - 3.4e-16 59.3 6.2 4.6e-16 58.8 6.2 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 zf-C2HC5 PF06221.13 KIY45920.1 - 5.2e-15 55.2 6.1 7.5e-15 54.7 6.1 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type GTP_cyclohydroI PF01227.22 KIY45921.1 - 4.3e-76 254.3 0.4 4.7e-76 254.2 0.4 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KIY45921.1 - 8.9e-05 22.6 0.0 0.00055 20.0 0.0 2.0 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 KIY45921.1 - 0.023 14.6 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain THOC2_N PF16134.5 KIY45922.1 - 7.6e-125 418.0 0.0 4.4e-124 415.4 0.0 2.0 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KIY45922.1 - 1.2e-82 277.5 0.0 1.2e-82 277.5 0.0 1.7 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KIY45922.1 - 2.4e-30 104.4 0.0 5.3e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Uso1_p115_C PF04871.13 KIY45923.1 - 0.7 10.3 20.3 1.8 9.0 9.5 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Class_IIIsignal PF04021.12 KIY45923.1 - 2.4 8.2 4.4 3.9 7.6 4.4 1.3 1 0 0 1 1 1 0 Class III signal peptide RED_C PF07807.11 KIY45923.1 - 2.8 8.4 10.5 0.58 10.6 6.4 1.7 1 1 1 2 2 2 0 RED-like protein C-terminal region COesterase PF00135.28 KIY45924.1 - 2.7e-101 340.0 0.0 4.7e-101 339.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY45924.1 - 0.00069 19.5 0.1 0.0046 16.9 0.0 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold HNH_2 PF13391.6 KIY45925.1 - 3e-07 30.5 0.8 7.9e-07 29.1 0.8 1.7 1 1 0 1 1 1 1 HNH endonuclease Glyco_hydro_35 PF01301.19 KIY45926.1 - 5.5e-83 279.2 3.8 9.4e-83 278.4 3.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIY45926.1 - 2.5e-56 189.2 6.0 1.2e-33 116.0 0.2 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIY45926.1 - 4e-49 166.9 1.6 7.5e-49 166.0 1.6 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIY45926.1 - 7e-21 73.6 0.1 2.2e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KIY45926.1 - 0.00081 18.8 0.1 0.0023 17.3 0.0 1.8 1 1 1 2 2 2 1 Beta-galactosidase A_deamin PF02137.18 KIY45927.1 - 6.5e-56 190.2 0.0 7.4e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Con-6 PF10346.9 KIY45929.1 - 1.2e-06 28.4 0.5 1.7e-06 27.9 0.5 1.2 1 0 0 1 1 1 1 Conidiation protein 6 Glyco_transf_8C PF08437.10 KIY45929.1 - 0.0045 17.0 0.2 0.0064 16.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 C-terminal Mob1_phocein PF03637.17 KIY45930.1 - 2.1e-26 92.9 0.0 3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family A_deamin PF02137.18 KIY45931.1 - 2.7e-52 178.2 0.0 3.1e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain MRP-L20 PF12824.7 KIY45931.1 - 0.24 11.5 0.1 27 4.9 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Glyco_hydro_35 PF01301.19 KIY45932.1 - 4.7e-86 289.3 1.5 7.5e-86 288.6 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIY45932.1 - 3e-56 188.9 6.4 1.2e-33 116.0 0.2 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIY45932.1 - 4.9e-49 166.6 2.7 9.2e-49 165.7 2.7 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIY45932.1 - 6.5e-21 73.7 0.1 2.2e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KIY45932.1 - 3.6e-05 23.4 0.0 6.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KIY45932.1 - 0.00087 18.7 0.0 0.0022 17.4 0.0 1.7 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_16 PF00722.21 KIY45933.1 - 5e-15 55.4 0.8 2.1e-14 53.4 0.8 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Drf_DAD PF06345.11 KIY45933.1 - 0.095 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 DRF Autoregulatory Domain PetL PF05115.14 KIY45933.1 - 0.43 10.6 1.8 0.74 9.8 1.8 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) DSPc PF00782.20 KIY45934.1 - 8.1e-30 103.4 0.0 9.6e-30 103.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIY45934.1 - 1.7e-05 25.1 0.1 2.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KIY45934.1 - 0.0012 19.0 0.0 0.0015 18.7 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KIY45934.1 - 0.0066 16.0 0.1 0.009 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KIY45934.1 - 0.062 13.0 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF3477 PF11963.8 KIY45934.1 - 0.12 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) Glu_syn_central PF04898.14 KIY45934.1 - 0.18 11.3 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain Melibiase_2 PF16499.5 KIY45935.1 - 5.5e-14 52.0 0.2 1.8e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KIY45935.1 - 1.4e-11 44.3 0.4 3e-11 43.2 0.1 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Hexokinase_2 PF03727.16 KIY45936.1 - 3.5e-77 259.1 0.0 4.8e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KIY45936.1 - 1.6e-71 240.4 0.1 2.2e-71 239.9 0.1 1.2 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.12 KIY45936.1 - 0.13 12.4 0.0 0.42 10.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Gly-zipper_Omp PF13488.6 KIY45936.1 - 4.9 7.2 9.0 3 7.9 3.3 2.5 2 0 0 2 2 2 0 Glycine zipper Amidase PF01425.21 KIY45937.1 - 3.9e-67 227.2 0.0 7e-66 223.0 0.0 2.1 1 1 0 1 1 1 1 Amidase PH PF00169.29 KIY45938.1 - 3.6e-10 40.3 0.0 4e-09 36.9 0.0 2.4 2 1 0 2 2 2 1 PH domain PH_6 PF15406.6 KIY45938.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIA PF03153.13 KIY45939.1 - 0.061 13.3 4.2 0.074 13.0 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sod_Fe_C PF02777.18 KIY45940.1 - 2.7e-11 43.5 0.1 2.8e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIY45940.1 - 0.05 14.1 0.0 0.12 12.9 0.0 1.7 1 1 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DAD PF02109.16 KIY45941.1 - 8.2e-47 158.0 0.8 9.1e-47 157.9 0.8 1.0 1 0 0 1 1 1 1 DAD family DUF2838 PF10998.8 KIY45942.1 - 1.9e-43 147.2 11.2 2.1e-43 147.1 8.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF1640 PF07798.11 KIY45942.1 - 0.0079 16.3 0.5 0.14 12.2 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Mitofilin PF09731.9 KIY45942.1 - 0.091 11.6 1.0 0.16 10.8 1.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Apolipoprotein PF01442.18 KIY45942.1 - 0.14 12.1 0.6 0.64 9.9 0.3 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SnoaL PF07366.12 KIY45943.1 - 3e-08 33.5 0.0 5.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KIY45943.1 - 3.8e-07 30.7 0.8 8.1e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 SnoaL-like domain FAD_oxidored PF12831.7 KIY45944.1 - 0.0013 18.1 0.2 0.0038 16.6 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY45944.1 - 0.059 12.6 0.3 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acyl-CoA_dh_1 PF00441.24 KIY45946.1 - 3.8e-26 92.1 0.2 6e-26 91.5 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIY45946.1 - 3.4e-16 59.2 0.6 7.8e-16 58.1 0.6 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KIY45946.1 - 6.3e-16 58.3 0.0 1.9e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KIY45946.1 - 2.9e-13 50.5 0.0 4.3e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIY45946.1 - 0.00011 22.5 0.1 0.00025 21.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Nucleoside_tran PF01733.18 KIY45947.1 - 1.4e-36 126.5 15.4 2.4e-35 122.4 15.4 2.3 1 1 0 1 1 1 1 Nucleoside transporter Ank_2 PF12796.7 KIY45949.1 - 2.5e-16 60.0 0.1 1.8e-07 31.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY45949.1 - 5.5e-15 55.5 0.3 3.7e-09 36.9 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY45949.1 - 1.7e-13 50.3 0.5 5.4e-05 23.5 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIY45949.1 - 2.2e-10 39.9 0.4 0.0031 17.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KIY45949.1 - 3.2e-09 36.9 0.1 0.00069 19.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KIY45949.1 - 0.00023 21.0 0.1 0.0028 17.5 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain Sec34 PF04136.15 KIY45949.1 - 0.18 11.7 2.2 0.28 11.1 1.0 1.8 2 0 0 2 2 2 0 Sec34-like family SKA2 PF16740.5 KIY45949.1 - 0.22 11.3 1.6 0.29 11.0 0.5 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 HR1 PF02185.16 KIY45949.1 - 0.25 11.5 3.8 5.4 7.2 0.1 2.8 2 1 0 2 2 2 0 Hr1 repeat Ank_2 PF12796.7 KIY45950.1 - 1.5e-12 47.9 0.0 6.5e-08 33.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIY45950.1 - 1.3e-11 44.3 0.0 7.6e-05 23.0 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KIY45950.1 - 3.7e-07 30.6 0.0 4.8e-06 27.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY45950.1 - 1.8e-06 27.8 0.4 0.0035 17.7 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KIY45950.1 - 0.00048 20.4 0.0 0.0032 17.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) URO-D PF01208.17 KIY45952.1 - 1.9e-131 438.3 0.0 2.2e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) COMPASS-Shg1 PF05205.12 KIY45953.1 - 1.8e-10 41.5 0.4 3.3e-10 40.6 0.4 1.4 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 EnY2 PF10163.9 KIY45953.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 p450 PF00067.22 KIY45954.1 - 1.3e-52 179.1 0.0 1.7e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Orbi_NS3 PF01616.16 KIY45955.1 - 0.0053 16.5 1.7 0.0074 16.0 0.3 1.8 1 1 1 2 2 2 1 Orbivirus NS3 DUF2809 PF10990.8 KIY45955.1 - 0.29 11.8 7.9 0.11 13.1 1.4 3.2 2 2 1 4 4 4 0 Protein of unknown function (DUF2809) DSPn PF14671.6 KIY45956.1 - 2.6e-40 138.1 0.0 5.2e-39 133.9 0.0 2.4 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KIY45956.1 - 3.7e-14 52.7 0.0 7.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY45956.1 - 0.00042 19.9 0.0 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIY45956.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KIY45956.1 - 0.24 11.3 0.0 0.36 10.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_L12 PF00542.19 KIY45957.1 - 4.5e-23 81.4 8.0 5.4e-22 77.9 2.0 2.3 2 1 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KIY45957.1 - 8.3e-12 44.6 3.7 8.3e-12 44.6 3.7 3.3 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 KIY45957.1 - 0.025 15.1 9.0 0.025 15.1 9.0 2.5 2 1 1 3 3 3 0 60s Acidic ribosomal protein Not3 PF04065.15 KIY45958.1 - 3e-90 301.7 20.3 5.1e-90 301.0 20.3 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KIY45958.1 - 3.2e-45 153.4 9.2 1.1e-44 151.7 9.2 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Roughex PF06020.11 KIY45958.1 - 0.35 9.9 5.4 0.61 9.1 5.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Cep57_MT_bd PF06657.13 KIY45958.1 - 1 9.8 8.1 0.7 10.4 1.4 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin_2 PF14523.6 KIY45958.1 - 2 8.8 11.4 0.14 12.5 4.4 2.6 2 1 1 3 3 3 0 Syntaxin-like protein MnmE_helical PF12631.7 KIY45958.1 - 2.2 8.4 8.8 0.78 9.9 5.4 1.8 1 1 1 2 2 2 0 MnmE helical domain HIP1_clath_bdg PF16515.5 KIY45958.1 - 3.2 8.4 25.7 2.7 8.7 6.1 3.7 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 COG5 PF10392.9 KIY45958.1 - 5.5 7.2 9.0 28 4.9 0.0 3.5 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 KIY45958.1 - 5.9 6.1 12.7 14 4.9 12.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SH3_1 PF00018.28 KIY45959.1 - 8.3e-22 76.5 0.0 1.9e-11 43.4 0.0 3.0 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 KIY45959.1 - 7.6e-16 57.6 0.0 5.7e-09 35.5 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KIY45959.1 - 6e-13 48.4 0.0 1.4e-07 31.2 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 KIY45959.1 - 1.7e-05 24.8 0.0 3.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 KIY45959.1 - 0.0054 16.6 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 PB1 domain DUF4648 PF15505.6 KIY45959.1 - 0.061 14.2 0.0 9.5 7.2 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4648) Tmemb_cc2 PF10267.9 KIY45959.1 - 0.32 10.1 1.4 0.45 9.6 1.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein EF-hand_4 PF12763.7 KIY45960.1 - 3.7e-18 65.4 0.1 2e-12 47.0 0.0 2.9 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand GAS PF13851.6 KIY45960.1 - 4.5e-06 26.2 28.8 4.4e-05 22.9 7.1 3.1 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding YabA PF06156.13 KIY45960.1 - 0.00031 21.3 19.9 0.021 15.4 0.6 4.6 1 1 4 5 5 5 3 Initiation control protein YabA Spc7 PF08317.11 KIY45960.1 - 0.00071 18.5 26.0 0.02 13.8 11.2 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein ZapB PF06005.12 KIY45960.1 - 0.0091 16.4 2.2 0.0091 16.4 2.2 4.3 1 1 2 3 3 2 1 Cell division protein ZapB bZIP_1 PF00170.21 KIY45960.1 - 0.012 15.7 1.2 0.012 15.7 1.2 5.7 5 1 1 6 6 6 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 KIY45960.1 - 0.012 15.6 30.5 0.086 12.9 11.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KIY45960.1 - 0.016 14.9 0.9 0.016 14.9 0.9 5.1 2 2 4 6 6 6 0 Septum formation initiator TPR_MLP1_2 PF07926.12 KIY45960.1 - 0.044 13.9 32.8 0.17 12.0 4.9 3.8 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 KIY45960.1 - 0.086 12.7 29.9 0.19 11.5 23.0 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 KIY45960.1 - 0.12 12.6 37.5 0.18 12.0 9.4 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KIY45960.1 - 0.13 12.8 35.5 0.063 13.8 15.0 3.5 1 1 3 4 4 4 0 Apg6 coiled-coil region WD40_alt PF14077.6 KIY45960.1 - 0.19 11.6 1.4 12 5.9 0.1 2.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif Transformer PF06495.11 KIY45960.1 - 0.23 11.5 9.1 0.81 9.8 9.1 1.9 1 0 0 1 1 1 0 Fruit fly transformer protein Jnk-SapK_ap_N PF09744.9 KIY45960.1 - 2.9 8.1 35.5 15 5.8 19.1 3.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 KIY45960.1 - 3.3 7.9 31.3 18 5.6 12.8 4.0 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 KIY45960.1 - 3.8 8.5 30.5 10 7.1 13.9 4.1 2 2 0 3 3 3 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 KIY45960.1 - 4.7 7.7 31.3 0.51 10.8 5.3 4.0 1 1 2 3 3 2 0 Centromere protein H (CENP-H) UPF0449 PF15136.6 KIY45960.1 - 5.3 7.6 15.9 0.36 11.3 4.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 TSC22 PF01166.18 KIY45960.1 - 5.5 7.4 13.9 0.59 10.5 1.9 4.2 2 2 3 5 5 5 0 TSC-22/dip/bun family MAD PF05557.13 KIY45960.1 - 7.5 4.8 27.8 0.72 8.1 19.9 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Fib_alpha PF08702.10 KIY45960.1 - 7.7 6.7 15.6 9 6.5 3.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Acyltransferase PF01553.21 KIY45961.1 - 1.5e-11 44.1 0.0 7.4e-11 41.8 0.0 1.9 1 1 1 2 2 2 2 Acyltransferase CopK PF11525.8 KIY45961.1 - 0.082 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Copper resistance protein K Ank_2 PF12796.7 KIY45962.1 - 2.9e-41 139.9 0.5 7.1e-15 55.4 0.9 4.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY45962.1 - 1.3e-30 105.4 10.8 3.2e-12 46.7 0.1 5.2 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY45962.1 - 5.7e-28 93.9 9.0 3.9e-05 23.7 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KIY45962.1 - 5.8e-21 74.3 10.8 3.6e-05 24.0 0.1 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KIY45962.1 - 5e-19 67.8 13.4 0.00026 21.3 0.0 7.4 6 1 1 7 7 7 4 Ankyrin repeat SPX PF03105.19 KIY45962.1 - 2.1e-10 41.1 0.7 3.2e-10 40.5 0.7 1.1 1 0 0 1 1 1 1 SPX domain Mt_ATP-synt_D PF05873.12 KIY45963.1 - 1.4e-14 54.2 0.9 1.7e-14 54.0 0.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) RPW8 PF05659.11 KIY45963.1 - 0.042 13.5 0.4 0.09 12.5 0.3 1.7 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TCO89 PF10452.9 KIY45963.1 - 0.044 12.8 0.1 0.053 12.5 0.1 1.0 1 0 0 1 1 1 0 TORC1 subunit TCO89 DUF3445 PF11927.8 KIY45964.1 - 6.8e-63 212.3 0.0 7.9e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) WD40 PF00400.32 KIY45965.1 - 3.4e-18 65.7 20.1 2.3e-07 31.4 1.7 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY45965.1 - 1.7e-06 28.2 0.1 0.011 16.0 0.0 4.3 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY45965.1 - 5.6e-05 23.1 0.1 0.0005 20.0 0.1 2.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIY45965.1 - 0.0065 15.8 0.0 0.032 13.6 0.0 1.9 2 0 0 2 2 2 1 WD40-like domain PALB2_WD40 PF16756.5 KIY45965.1 - 0.018 14.0 4.0 0.03 13.2 0.4 2.3 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain IKI3 PF04762.12 KIY45965.1 - 0.031 12.3 0.0 0.63 8.0 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PQQ_3 PF13570.6 KIY45965.1 - 0.085 13.4 0.6 2 9.0 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain RRM_1 PF00076.22 KIY45966.1 - 6e-17 61.2 0.0 8e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY45966.1 - 0.0023 17.5 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF727 PF05303.12 KIY45966.1 - 0.24 11.5 0.2 0.52 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF727) Ribosomal_L18 PF17135.4 KIY45967.1 - 2.1e-88 294.6 1.9 2.4e-88 294.5 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KIY45967.1 - 0.0015 19.2 0.0 0.0015 19.2 0.0 2.2 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GN3L_Grn1 PF08701.11 KIY45968.1 - 2.4e-22 78.8 6.4 6.8e-22 77.4 6.4 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KIY45968.1 - 1.9e-08 34.4 0.8 7.4e-07 29.3 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY45968.1 - 5.5e-07 29.6 0.1 0.0077 16.1 0.1 2.7 3 0 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 KIY45968.1 - 0.00014 21.3 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KIY45968.1 - 0.00017 21.2 0.0 0.011 15.3 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIY45968.1 - 0.02 15.0 8.3 0.34 10.9 0.1 4.1 3 2 1 4 4 4 0 Dynamin family Septin PF00735.18 KIY45968.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin TRAP_alpha PF03896.16 KIY45968.1 - 0.22 10.7 2.4 0.41 9.8 2.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit YL1 PF05764.13 KIY45968.1 - 0.37 10.9 16.2 0.13 12.3 5.8 2.3 2 0 0 2 2 2 0 YL1 nuclear protein NOA36 PF06524.12 KIY45968.1 - 2.9 7.1 8.3 5.7 6.2 8.3 1.4 1 0 0 1 1 1 0 NOA36 protein Tti2 PF10521.9 KIY45969.1 - 3.7e-42 144.8 0.0 7.7e-42 143.8 0.0 1.4 1 1 0 1 1 1 1 Tti2 family EF-hand_1 PF00036.32 KIY45971.1 - 2.6e-28 95.4 11.0 2e-07 30.1 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIY45971.1 - 5.5e-24 84.4 5.2 5.7e-14 52.3 1.6 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY45971.1 - 2.2e-22 77.0 6.3 1.6e-05 24.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KIY45971.1 - 6.2e-18 63.4 12.8 2.8e-05 23.4 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIY45971.1 - 2.1e-12 46.7 13.3 0.00058 19.6 0.8 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KIY45971.1 - 3.5e-07 30.1 5.5 0.00017 21.5 0.5 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIY45971.1 - 4.9e-06 26.8 0.0 0.036 14.4 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KIY45971.1 - 0.0065 16.8 0.2 0.53 10.6 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 KIY45971.1 - 0.16 12.2 1.9 0.92 9.8 1.2 2.4 2 1 0 2 2 2 0 Dockerin type I domain MnmE_helical PF12631.7 KIY45972.1 - 2.1e-50 171.7 1.1 2.7e-50 171.4 1.1 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KIY45972.1 - 2.5e-35 121.3 0.0 5.5e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KIY45972.1 - 5.9e-19 68.2 0.0 1.2e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIY45972.1 - 4.9e-05 23.4 0.0 0.00051 20.1 0.0 2.0 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KIY45972.1 - 0.00011 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KIY45972.1 - 0.0058 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 KIY45972.1 - 0.0085 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY45972.1 - 0.043 14.3 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIY45972.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KIY45972.1 - 0.19 11.3 0.2 17 4.9 0.1 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4597 PF15366.6 KIY45973.1 - 0.078 12.7 0.4 0.2 11.4 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) 2-oxoacid_dh PF00198.23 KIY45974.1 - 1e-48 165.8 0.0 1.9e-48 165.0 0.0 1.4 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIY45974.1 - 2.8e-17 62.3 0.0 5.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KIY45974.1 - 7.2e-12 45.4 0.5 3e-11 43.5 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KIY45974.1 - 0.0041 16.9 0.1 0.0073 16.1 0.1 1.4 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_D23 PF16576.5 KIY45974.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Trypsin_2 PF13365.6 KIY45975.1 - 0.012 16.5 0.0 0.024 15.5 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain COE1_HLH PF16423.5 KIY45975.1 - 0.04 13.6 1.3 0.11 12.2 1.3 1.7 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain p450 PF00067.22 KIY45976.1 - 4e-51 174.2 0.0 4.6e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MBOAT PF03062.19 KIY45977.1 - 1.4e-43 149.6 5.8 5e-43 147.8 5.0 2.2 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MARVEL PF01284.23 KIY45978.1 - 7.1e-10 39.1 20.2 1.2e-09 38.4 20.2 1.4 1 0 0 1 1 1 1 Membrane-associating domain SUa-2TM PF18179.1 KIY45978.1 - 4.3 6.5 7.4 0.08 12.2 0.5 1.5 2 0 0 2 2 2 0 SMODS- and Ubiquitin system-associated 2TM effector domain MARVEL PF01284.23 KIY45979.1 - 6.9e-11 42.4 15.8 7.3e-11 42.3 15.1 1.3 1 1 0 1 1 1 1 Membrane-associating domain WD40 PF00400.32 KIY45980.1 - 6.7e-16 58.4 18.4 0.0038 18.0 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY45980.1 - 1.7e-07 31.5 0.9 0.054 13.8 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY45981.1 - 3.9e-26 91.8 0.0 6.4e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Fungal_trans PF04082.18 KIY45982.1 - 6.9e-07 28.6 0.3 1.6e-06 27.4 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY45983.1 - 1e-06 28.8 7.4 1.6e-06 28.2 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.28 KIY45985.1 - 2e-08 34.2 0.2 3.3e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGS PF00615.19 KIY45986.1 - 3.6e-41 140.1 0.5 1e-40 138.7 0.5 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KIY45986.1 - 1.1e-14 54.2 0.0 3.9e-07 30.0 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1488 PF07369.11 KIY45986.1 - 0.087 12.8 0.0 0.5 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) ERCC3_RAD25_C PF16203.5 KIY45987.1 - 0.0018 17.5 0.1 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Methyltransf_16 PF10294.9 KIY45988.1 - 0.0034 17.1 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Adap_comp_sub PF00928.21 KIY45989.1 - 3.2e-50 171.0 0.0 4.4e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIY45989.1 - 1.7e-05 24.8 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Bystin PF05291.11 KIY45990.1 - 1.8e-122 408.2 0.0 2.3e-122 407.9 0.0 1.1 1 0 0 1 1 1 1 Bystin Nop14 PF04147.12 KIY45990.1 - 0.0093 14.2 4.5 0.012 13.9 4.5 1.1 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.12 KIY45990.1 - 4.8 6.4 11.0 7 5.9 11.0 1.1 1 0 0 1 1 1 0 NOA36 protein GDP_Man_Dehyd PF16363.5 KIY45991.1 - 6.9e-58 196.6 0.0 8.5e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIY45991.1 - 2.9e-47 161.2 0.0 4.2e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY45991.1 - 2.1e-08 33.5 0.0 3.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY45991.1 - 2e-07 30.5 0.1 0.0015 17.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KIY45991.1 - 2.3e-06 27.0 0.5 0.005 16.0 0.1 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KIY45991.1 - 3.5e-05 23.0 0.0 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Abhydrolase_1 PF00561.20 KIY45992.1 - 2.1e-06 27.6 0.1 0.00013 21.8 0.1 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 KIY45992.1 - 0.00033 20.1 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.7 KIY45992.1 - 0.0008 20.1 0.0 0.0018 18.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIY45992.1 - 0.001 18.6 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIY45992.1 - 0.012 14.9 0.0 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2458 PF10454.9 KIY45993.1 - 1.7e-06 27.8 1.6 2.3e-06 27.4 1.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2458) NAP PF00956.18 KIY45993.1 - 0.0011 18.2 0.3 0.0011 18.2 0.3 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DGCR6 PF07324.11 KIY45993.1 - 0.0011 18.6 0.8 0.0021 17.7 0.8 1.4 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein OmpH PF03938.14 KIY45993.1 - 0.064 13.6 1.3 0.08 13.3 1.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SecD-TM1 PF13721.6 KIY45993.1 - 0.082 13.4 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 SecD export protein N-terminal TM region CENP-F_leu_zip PF10473.9 KIY45994.1 - 0.0029 17.6 15.4 0.012 15.6 15.2 2.2 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 KIY45994.1 - 0.0089 15.9 6.1 0.17 11.7 2.6 2.5 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 KIY45994.1 - 0.012 16.0 14.6 1.6 9.2 0.9 3.5 2 1 1 3 3 3 0 Cell division protein ZapB FMN_bind_2 PF04299.12 KIY45994.1 - 0.086 12.5 1.5 1.8 8.3 0.2 3.2 3 0 0 3 3 3 0 Putative FMN-binding domain FlgN PF05130.12 KIY45994.1 - 0.087 13.3 8.7 0.21 12.1 8.7 1.6 1 0 0 1 1 1 0 FlgN protein Ax_dynein_light PF10211.9 KIY45994.1 - 0.12 12.3 8.1 0.73 9.8 0.0 2.9 1 1 0 2 2 2 0 Axonemal dynein light chain Pox_A_type_inc PF04508.12 KIY45994.1 - 0.2 11.6 3.1 1.2 9.1 0.0 3.0 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat DUF724 PF05266.14 KIY45994.1 - 0.2 11.5 3.0 4.1 7.2 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 KIY45994.1 - 0.26 11.5 9.9 6.9 6.9 0.0 3.4 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 GAS PF13851.6 KIY45994.1 - 0.32 10.3 9.2 0.72 9.2 9.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding JIP_LZII PF16471.5 KIY45994.1 - 0.36 11.0 13.3 0.06 13.5 2.6 3.5 4 0 0 4 4 3 0 JNK-interacting protein leucine zipper II PRKG1_interact PF15898.5 KIY45994.1 - 0.43 11.5 10.1 1.3 10.0 3.8 3.2 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain YscO PF07321.12 KIY45994.1 - 0.56 10.2 15.7 0.013 15.5 5.1 2.5 1 1 1 2 2 2 0 Type III secretion protein YscO APG6_N PF17675.1 KIY45994.1 - 1 9.9 18.7 4.4 7.8 17.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 KIY45994.1 - 1.2 8.4 9.9 2.4 7.4 5.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) FapA PF03961.13 KIY45994.1 - 1.5 7.3 4.1 1.8 7.1 1.1 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 KIY45994.1 - 1.8 8.6 15.2 13 5.9 0.4 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KIY45994.1 - 2 8.7 13.3 3.2 8.1 1.3 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Nup54 PF13874.6 KIY45994.1 - 2.6 8.2 7.4 3.7 7.7 5.3 2.2 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1515 PF07439.11 KIY45994.1 - 3 7.9 6.4 0.45 10.6 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TMF_TATA_bd PF12325.8 KIY45994.1 - 4.7 7.5 12.8 5 7.4 4.3 3.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding KASH_CCD PF14662.6 KIY45994.1 - 7.9 6.3 13.9 13 5.5 10.7 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 KIY45994.1 - 9.9 6.5 8.1 57 4.0 0.1 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Aft1_HRA PF11786.8 KIY45995.1 - 4.7e-17 62.1 14.9 4.7e-17 62.1 14.9 3.1 3 1 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 KIY45995.1 - 5.9e-08 32.7 9.2 5.9e-08 32.7 9.2 1.8 2 0 0 2 2 2 1 bZIP transcription factor Aft1_OSA PF11785.8 KIY45995.1 - 1.1e-05 25.8 5.3 1.1e-05 25.8 5.3 4.0 4 1 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 KIY45995.1 - 5e-05 23.3 9.0 5e-05 23.3 9.0 2.3 2 0 0 2 2 2 1 Basic region leucine zipper LAP1C PF05609.12 KIY45995.1 - 0.64 9.0 8.4 0.98 8.4 8.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF5094 PF17015.5 KIY45995.1 - 1.2 9.3 9.5 2.5 8.2 9.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) Cyclin PF08613.11 KIY45996.1 - 8.8e-43 146.5 0.5 9.9e-43 146.3 0.5 1.0 1 0 0 1 1 1 1 Cyclin Aldo_ket_red PF00248.21 KIY45997.1 - 1.1e-38 133.2 0.0 1.6e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Guanylate_kin PF00625.21 KIY45998.1 - 2.6e-62 209.7 0.0 3.2e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KIY45998.1 - 1.5e-07 31.9 0.0 2.4e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KIY45998.1 - 0.00015 22.0 0.0 0.00058 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KIY45998.1 - 0.00027 21.0 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY45998.1 - 0.00033 21.2 0.0 0.00066 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY45998.1 - 0.00066 20.0 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIY45998.1 - 0.00093 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 KIY45998.1 - 0.0028 17.7 0.0 0.0064 16.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 KIY45998.1 - 0.0074 16.8 0.0 0.0077 16.8 0.0 1.5 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 KIY45998.1 - 0.0089 16.4 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.15 KIY45998.1 - 0.015 15.3 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KIY45998.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KIY45998.1 - 0.025 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KIY45998.1 - 0.042 13.8 0.0 0.06 13.3 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIY45998.1 - 0.045 14.2 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIY45998.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KIY45998.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 1 0 NTPase Septin PF00735.18 KIY45998.1 - 0.089 12.0 0.0 0.099 11.9 0.0 1.3 1 1 0 1 1 1 0 Septin AAA_28 PF13521.6 KIY45998.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIY45998.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KIY45998.1 - 0.13 11.4 0.0 0.34 10.1 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 KIY45998.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KIY45998.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase Roc PF08477.13 KIY45998.1 - 0.21 11.8 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PHD PF00628.29 KIY45999.1 - 1.5e-07 31.2 7.0 2.3e-07 30.6 7.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KIY45999.1 - 3e-05 24.2 2.0 3.7e-05 23.9 2.0 1.2 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KIY45999.1 - 0.0046 17.1 1.5 0.0055 16.9 1.5 1.2 1 0 0 1 1 1 1 PHD-zinc-finger like domain Ion_trans PF00520.31 KIY46000.1 - 3.2e-22 78.9 22.9 4.6e-22 78.5 22.9 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KIY46000.1 - 4.2e-12 45.9 5.8 4.2e-12 45.9 5.8 2.9 2 1 1 3 3 3 1 Ion channel Lig_chan PF00060.26 KIY46000.1 - 0.01 15.7 0.5 0.01 15.7 0.5 2.1 2 0 0 2 2 2 1 Ligand-gated ion channel CCDC24 PF15669.5 KIY46000.1 - 0.037 13.9 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF4407 PF14362.6 KIY46000.1 - 0.11 11.8 3.2 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ORC2 PF04084.14 KIY46001.1 - 3.3e-91 305.7 0.0 3.9e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 CMAS PF02353.20 KIY46002.1 - 2.8e-11 43.2 0.0 3.3e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RVT_1 PF00078.27 KIY46004.1 - 3.9e-08 33.1 0.2 7.7e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_int_trans PF05718.12 KIY46004.1 - 0.073 11.8 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor zf-RVT PF13966.6 KIY46005.1 - 1.3e-05 25.8 0.8 1.3e-05 25.8 0.8 2.3 2 2 0 2 2 2 1 zinc-binding in reverse transcriptase p450 PF00067.22 KIY46006.1 - 1.2e-64 218.8 0.0 3.5e-64 217.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 KIY46009.1 - 5.9e-08 32.9 0.0 1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2263 PF10021.9 KIY46010.1 - 2.2e-41 141.6 0.0 2.9e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) TMEM223 PF14640.6 KIY46011.1 - 0.0071 16.5 0.0 0.0099 16.1 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 Mito_carr PF00153.27 KIY46012.1 - 1.4e-53 178.8 4.6 4.3e-18 65.0 0.0 4.0 2 2 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIY46012.1 - 0.0073 15.5 1.4 0.012 14.8 0.2 2.0 2 1 1 3 3 3 1 Gammaproteobacterial serine protease PsbX PF06596.11 KIY46012.1 - 0.3 11.1 5.6 2.5 8.2 0.1 2.9 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) Hydrolase_4 PF12146.8 KIY46013.1 - 1.6e-53 181.5 0.0 1.9e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY46013.1 - 4e-13 50.5 0.0 5.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY46013.1 - 4e-12 46.3 0.2 6e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIY46013.1 - 0.0028 17.5 0.4 8 6.2 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF1749 PF08538.10 KIY46013.1 - 0.064 12.3 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Esterase PF00756.20 KIY46013.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.13 KIY46013.1 - 0.16 11.6 0.0 0.73 9.5 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KIY46013.1 - 0.2 11.1 0.7 0.56 9.7 0.0 2.0 2 1 1 3 3 3 0 Prolyl oligopeptidase family ABC_tran PF00005.27 KIY46015.1 - 8e-34 117.1 0.0 1.5e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KIY46015.1 - 7.3e-32 111.1 13.3 1.1e-31 110.5 13.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KIY46015.1 - 3.3e-05 23.4 0.4 0.0002 20.9 0.4 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIY46015.1 - 0.0079 16.5 0.2 0.047 14.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY46015.1 - 0.01 15.5 0.1 0.029 14.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY46015.1 - 0.012 16.0 0.2 0.047 14.1 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 KIY46015.1 - 0.026 14.2 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 KIY46015.1 - 0.033 14.0 0.1 0.11 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KIY46015.1 - 0.046 14.1 0.1 0.81 10.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FAST_2 PF08368.12 KIY46015.1 - 0.11 13.3 0.0 0.31 11.8 0.0 1.8 2 0 0 2 2 1 0 FAST kinase-like protein, subdomain 2 AAA_10 PF12846.7 KIY46015.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.12 KIY46015.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 KIY46015.1 - 0.17 11.7 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase SbcCD_C PF13558.6 KIY46015.1 - 1.2 9.4 3.6 5.3 7.3 0.3 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RRM_1 PF00076.22 KIY46016.1 - 2e-21 75.6 0.0 2.4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY46016.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.19 KIY46017.1 - 3.4e-12 46.6 0.6 3.4e-12 46.6 0.6 2.4 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY46017.1 - 3.2e-05 24.4 0.3 3.2e-05 24.4 0.3 2.2 1 1 1 2 2 2 1 HMG-box domain TENA_THI-4 PF03070.16 KIY46018.1 - 1.8e-08 34.5 0.3 2.7e-08 33.9 0.3 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Ribosomal_L16 PF00252.18 KIY46019.1 - 1.5e-37 128.6 0.2 1.8e-37 128.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF294_C PF10335.9 KIY46019.1 - 0.11 12.3 0.2 0.21 11.3 0.1 1.5 1 1 1 2 2 2 0 Putative nucleotidyltransferase substrate binding domain PRP3 PF08572.10 KIY46020.1 - 9.5e-67 225.0 0.0 1.8e-66 224.1 0.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KIY46020.1 - 2.4e-41 141.2 0.0 2.4e-41 141.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Q_salvage PF10343.9 KIY46021.1 - 8.8e-12 45.2 0.0 9.6e-08 31.9 0.0 2.4 2 1 0 2 2 2 2 Potential Queuosine, Q, salvage protein family Ald_Xan_dh_C2 PF02738.18 KIY46021.1 - 0.087 11.3 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase AA_kinase PF00696.28 KIY46021.1 - 0.091 12.3 0.1 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Amino acid kinase family NAD_kinase PF01513.21 KIY46022.1 - 6e-72 242.3 0.0 1.3e-71 241.2 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase NOA36 PF06524.12 KIY46022.1 - 0.54 9.5 2.4 0.75 9.1 2.4 1.2 1 0 0 1 1 1 0 NOA36 protein APH PF01636.23 KIY46023.1 - 5.4e-14 52.7 0.0 3e-13 50.2 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIY46023.1 - 5e-06 25.6 0.0 0.04 12.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.25 KIY46023.1 - 0.018 14.4 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain SMC_hinge PF06470.13 KIY46024.1 - 0.17 12.2 0.0 0.49 10.7 0.0 1.7 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain Pex14_N PF04695.13 KIY46024.1 - 0.64 10.7 6.8 23 5.6 0.0 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Retrotrans_gag PF03732.17 KIY46025.1 - 0.036 14.3 0.1 0.044 14.1 0.1 1.1 1 0 0 1 1 1 0 Retrotransposon gag protein Transp_cyt_pur PF02133.15 KIY46028.1 - 7.3e-115 384.2 36.9 8.4e-115 384.0 36.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DNA_pol_E_B PF04042.16 KIY46029.1 - 7e-29 100.7 0.1 9.9e-29 100.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KIY46029.1 - 6.2e-05 23.1 0.3 0.0049 16.9 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal AA_permease PF00324.21 KIY46030.1 - 3.2e-114 382.2 35.7 3.7e-114 381.9 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY46030.1 - 4.8e-34 117.9 37.7 5.9e-34 117.6 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease E1_dh PF00676.20 KIY46031.1 - 1.2e-112 375.7 0.0 1.4e-112 375.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KIY46031.1 - 0.00024 20.4 0.0 0.00037 19.8 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Tim17 PF02466.19 KIY46032.1 - 1.9e-31 108.7 9.6 2.3e-31 108.5 9.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MFS_1 PF07690.16 KIY46032.1 - 0.035 13.0 3.4 0.17 10.8 0.1 2.1 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF543 PF04418.12 KIY46032.1 - 0.056 13.4 0.5 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Arrestin_N PF00339.29 KIY46033.1 - 2.7e-09 37.2 0.0 5.2e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KIY46033.1 - 6.8e-09 36.3 0.0 2.6e-08 34.4 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KIY46033.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like SAP18 PF06487.12 KIY46034.1 - 9.1e-32 110.1 0.0 1.1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) PhoLip_ATPase_C PF16212.5 KIY46035.1 - 4.8e-53 180.5 22.0 4.8e-53 180.5 22.0 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIY46035.1 - 1.2e-15 56.9 7.1 2.9e-15 55.7 7.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIY46035.1 - 7.8e-15 55.7 0.1 5.1e-12 46.5 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIY46035.1 - 1e-12 47.9 0.0 1e-12 47.9 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KIY46035.1 - 9.9e-09 35.2 0.0 1.8e-07 31.1 0.0 2.6 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIY46035.1 - 0.0053 16.5 0.1 0.014 15.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF92 PF01940.16 KIY46036.1 - 2.5e-51 174.4 10.8 3.1e-51 174.1 10.8 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 RNase_P_Rpp14 PF01900.19 KIY46037.1 - 2.8e-28 98.2 0.0 3.6e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF535 PF04393.13 KIY46037.1 - 0.14 11.4 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF535) TrkH PF02386.16 KIY46038.1 - 1.3e-83 281.2 12.5 1.2e-56 192.2 0.2 3.1 2 1 1 3 3 3 3 Cation transport protein Ion_trans_2 PF07885.16 KIY46038.1 - 7.8 6.5 15.7 0.071 13.1 5.7 2.5 2 0 0 2 2 2 0 Ion channel MIF4G PF02854.19 KIY46040.1 - 2e-58 197.6 0.1 3.5e-58 196.7 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KIY46040.1 - 1.2e-08 35.0 0.3 3.1e-08 33.6 0.1 1.9 2 0 0 2 2 2 1 MA3 domain TFIIA PF03153.13 KIY46040.1 - 1.2 9.1 8.1 0.4 10.6 4.3 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SMC_N PF02463.19 KIY46041.1 - 4.7e-19 68.7 0.0 3e-18 66.1 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY46041.1 - 1.3e-15 58.4 0.9 1.3e-15 58.4 0.9 5.7 3 2 2 5 5 4 1 AAA domain AAA_15 PF13175.6 KIY46041.1 - 8.1e-10 38.9 25.1 4.8e-08 33.1 5.6 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KIY46041.1 - 0.0043 16.8 0.0 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF2205 PF10224.9 KIY46041.1 - 0.022 14.7 1.2 0.022 14.7 1.2 5.2 5 1 0 5 5 5 0 Short coiled-coil protein BLOC1_2 PF10046.9 KIY46041.1 - 0.18 12.1 38.1 1.5 9.1 0.4 7.1 6 0 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.13 KIY46041.1 - 0.47 11.2 47.1 0.031 15.0 3.3 6.0 5 0 0 5 5 5 0 Occludin homology domain AAA_27 PF13514.6 KIY46041.1 - 1.1 8.9 0.0 1.1 8.9 0.0 4.2 4 1 1 5 5 4 0 AAA domain HALZ PF02183.18 KIY46041.1 - 1.2 9.4 7.7 3.1 8.1 2.0 4.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper AAA PF00004.29 KIY46041.1 - 2.8 8.4 4.7 2.1 8.8 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) tRNA-synt_1e PF01406.19 KIY46041.1 - 4.7 6.5 9.7 0.081 12.3 1.6 2.2 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Sulfatase_C PF14707.6 KIY46041.1 - 8.2 7.2 6.0 6.1 7.6 0.4 3.5 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase PH PF00169.29 KIY46042.1 - 0.00024 21.6 0.0 0.00045 20.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Syntaxin_2 PF14523.6 KIY46042.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.1 2 0 0 2 2 2 0 Syntaxin-like protein Nnf1 PF03980.14 KIY46042.1 - 4.6 7.7 6.4 17 5.9 0.2 3.3 4 0 0 4 4 4 0 Nnf1 CBFD_NFYB_HMF PF00808.23 KIY46043.1 - 9.5e-20 70.7 1.2 1.2e-19 70.4 1.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY46043.1 - 6.3e-14 52.5 0.2 7e-14 52.3 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KIY46043.1 - 0.0072 16.6 0.1 0.016 15.5 0.1 1.5 1 1 1 2 2 2 1 CENP-S associating Centromere protein X TAFII28 PF04719.14 KIY46043.1 - 0.029 14.5 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TAF PF02969.17 KIY46043.1 - 0.036 14.2 0.5 0.057 13.6 0.3 1.4 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) ubiquitin PF00240.23 KIY46044.1 - 1.1e-06 28.3 0.2 5.7e-06 26.0 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KIY46044.1 - 1.5e-05 25.4 0.2 6.1e-05 23.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain RAWUL PF16207.5 KIY46044.1 - 0.0026 18.4 0.0 0.0031 18.1 0.0 1.1 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD PF11976.8 KIY46044.1 - 0.0044 16.8 0.2 0.033 14.0 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.18 KIY46044.1 - 0.0059 16.8 0.0 0.0074 16.4 0.0 1.1 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF4431 PF14485.6 KIY46044.1 - 0.026 14.3 0.0 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) UN_NPL4 PF11543.8 KIY46044.1 - 0.074 13.5 0.0 0.092 13.2 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 PEP_mutase PF13714.6 KIY46045.1 - 3.4e-45 154.4 3.8 1.4e-44 152.4 4.4 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KIY46045.1 - 7.1e-19 67.7 1.4 9.8e-19 67.2 1.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family RNase_PH PF01138.21 KIY46046.1 - 2.9e-28 99.0 0.0 4.3e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIY46046.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ctr PF04145.15 KIY46051.1 - 9.8e-34 117.1 3.7 1.8e-33 116.2 3.7 1.5 1 0 0 1 1 1 1 Ctr copper transporter family NDT80_PhoG PF05224.12 KIY46052.1 - 0.56 10.4 6.2 1.3 9.2 0.1 2.3 1 1 1 2 2 2 0 NDT80 / PhoG like DNA-binding family Borrelia_P83 PF05262.11 KIY46052.1 - 0.84 8.1 27.5 1.8 7.0 27.5 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein TFB6 PF17110.5 KIY46053.1 - 1.5e-05 24.8 0.0 2.5e-05 24.1 0.0 1.4 2 0 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH F-box-like PF12937.7 KIY46055.1 - 0.37 10.7 3.5 0.31 11.0 0.9 2.3 2 1 0 2 2 2 0 F-box-like F-box-like PF12937.7 KIY46058.1 - 0.49 10.3 3.5 0.35 10.8 0.8 2.2 2 1 0 2 2 2 0 F-box-like SUR7 PF06687.12 KIY46059.1 - 1.4e-17 64.0 12.9 1.7e-17 63.7 12.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family FSH1 PF03959.13 KIY46062.1 - 1.9e-48 164.9 0.0 2.2e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KIY46062.1 - 0.00073 19.3 0.1 0.083 12.5 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY46062.1 - 0.014 14.7 0.1 0.21 10.8 0.0 2.3 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KIY46062.1 - 0.06 13.1 0.1 4.5 7.0 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KIY46062.1 - 0.17 12.5 8.8 7.3 7.1 7.5 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2884 PF11101.8 KIY46062.1 - 0.27 10.7 0.0 0.41 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DnaJ PF00226.31 KIY46063.1 - 1.6e-11 44.1 0.0 3.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4203 PF13886.6 KIY46064.1 - 1.5e-09 37.9 24.2 1.6e-09 37.7 24.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Orn_Arg_deC_N PF02784.16 KIY46065.1 - 5e-63 212.8 0.0 4.9e-62 209.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KIY46065.1 - 6.8e-19 67.9 0.0 2.7e-18 66.0 0.0 2.0 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF3721 PF12518.8 KIY46065.1 - 0.11 12.4 0.2 0.29 11.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF1192 PF06698.11 KIY46066.1 - 0.065 13.3 5.4 0.13 12.4 2.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Spc7 PF08317.11 KIY46066.1 - 0.12 11.2 3.2 0.43 9.4 3.2 1.9 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KIY46066.1 - 0.15 12.1 7.0 0.18 11.9 2.8 2.8 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KIY46066.1 - 0.28 10.8 7.6 0.98 9.0 6.6 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 KIY46066.1 - 0.37 10.1 6.7 0.55 9.5 3.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TolA_bind_tri PF16331.5 KIY46066.1 - 2 8.5 5.3 23 5.2 0.0 3.0 3 0 0 3 3 3 0 TolA binding protein trimerisation LPP PF04728.13 KIY46066.1 - 2.5 8.5 5.7 17 5.9 0.6 4.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper JIP_LZII PF16471.5 KIY46066.1 - 3.5 7.9 5.6 2.7 8.2 0.5 3.0 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II C2 PF00168.30 KIY46067.1 - 6.9e-05 23.1 0.0 0.00018 21.7 0.0 1.8 1 1 0 1 1 1 1 C2 domain ER_lumen_recept PF00810.18 KIY46068.1 - 2e-55 187.7 8.5 2.9e-55 187.1 8.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KIY46068.1 - 0.00063 19.5 8.1 0.16 11.8 0.1 4.0 3 1 1 4 4 4 2 PQ loop repeat HEAT_EZ PF13513.6 KIY46069.1 - 3.7e-28 97.6 14.3 2.6e-14 53.3 0.0 11.4 11 2 1 12 12 12 2 HEAT-like repeat HEAT PF02985.22 KIY46069.1 - 2.4e-23 80.2 13.5 8.2e-05 22.5 0.0 10.3 10 0 0 10 10 9 5 HEAT repeat HEAT_2 PF13646.6 KIY46069.1 - 2.9e-18 66.0 0.2 9.6e-05 22.7 0.0 7.6 6 2 2 9 9 9 4 HEAT repeats Vac14_Fab1_bd PF12755.7 KIY46069.1 - 5.7e-08 33.2 0.0 0.13 12.8 0.0 5.0 4 1 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KIY46069.1 - 2.2e-07 31.1 0.2 2.7 8.0 0.0 5.2 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.8 KIY46069.1 - 6.4e-06 26.0 2.8 0.014 15.3 0.1 4.5 5 0 0 5 5 5 2 Domain of unknown function (DUF3437) Arm PF00514.23 KIY46069.1 - 3.4e-05 23.7 0.2 0.48 10.5 0.0 5.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 KIY46069.1 - 0.0013 19.0 0.1 1.5 9.2 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 KIY46069.1 - 0.0029 16.3 0.1 4.7 5.6 0.0 3.4 3 0 0 3 3 3 2 Adaptin N terminal region Tti2 PF10521.9 KIY46069.1 - 0.0083 15.7 0.1 3.6 7.1 0.0 3.5 2 1 1 3 3 3 1 Tti2 family CLASP_N PF12348.8 KIY46069.1 - 0.017 14.7 0.0 9.3 5.7 0.0 3.9 4 0 0 4 4 4 0 CLASP N terminal Xpo1 PF08389.12 KIY46069.1 - 0.085 12.9 0.2 20 5.3 0.0 3.5 4 0 0 4 4 4 0 Exportin 1-like protein RTP1_C1 PF10363.9 KIY46069.1 - 0.15 12.3 0.0 14 5.9 0.0 3.8 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 YEATS PF03366.16 KIY46071.1 - 4.7e-37 125.8 0.2 9e-37 124.9 0.2 1.5 1 0 0 1 1 1 1 YEATS family PEP_mutase PF13714.6 KIY46072.1 - 3.3e-43 147.8 4.3 4.3e-43 147.5 4.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KIY46072.1 - 3.6e-19 68.6 1.3 4.8e-19 68.3 1.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family RabGAP-TBC PF00566.18 KIY46073.1 - 1.6e-29 103.2 0.0 3.2e-29 102.1 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain MFS_1 PF07690.16 KIY46074.1 - 7.1e-11 41.6 10.4 8.6e-11 41.3 10.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY46074.1 - 0.00048 19.1 2.7 0.00057 18.9 2.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Ion_trans_2 PF07885.16 KIY46074.1 - 0.001 19.0 1.3 0.001 19.0 1.3 1.7 2 0 0 2 2 2 1 Ion channel OATP PF03137.20 KIY46074.1 - 0.018 13.3 2.1 0.76 8.0 0.1 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EXS PF03124.14 KIY46074.1 - 0.046 13.0 1.0 0.061 12.6 1.0 1.0 1 0 0 1 1 1 0 EXS family LapA_dom PF06305.11 KIY46074.1 - 0.94 9.3 0.1 0.94 9.3 0.1 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain FixQ PF05545.11 KIY46074.1 - 2.1 8.4 10.7 0.54 10.3 1.0 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PAP_PilO PF06864.12 KIY46075.1 - 0.084 11.7 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Plavaka PF18759.1 KIY46077.1 - 2.8e-116 388.3 0.0 3.9e-116 387.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIY46077.1 - 0.09 13.3 0.2 0.34 11.5 0.2 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type NOA36 PF06524.12 KIY46077.1 - 1.6 8.0 4.3 2.6 7.3 4.3 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KIY46077.1 - 8.8 4.4 8.9 13 3.8 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.22 KIY46078.1 - 2.8e-32 110.4 0.0 2e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3932 PF13068.6 KIY46078.1 - 0.0048 17.2 0.0 4.9 7.5 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3932) RRM_7 PF16367.5 KIY46078.1 - 0.021 15.0 0.0 5.6 7.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif DUF2811 PF10929.8 KIY46079.1 - 0.13 12.6 0.1 0.24 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Lectin_leg-like PF03388.13 KIY46080.1 - 8.1e-63 211.8 0.5 1.1e-62 211.5 0.5 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KIY46080.1 - 1.5e-06 27.9 0.0 0.0011 18.6 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain RRM_1 PF00076.22 KIY46082.1 - 2.6e-13 49.6 0.0 2.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Carn_acyltransf PF00755.20 KIY46083.1 - 2.3e-13 49.7 0.0 5.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase NmrA PF05368.13 KIY46084.1 - 1.4e-27 96.7 0.0 2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY46084.1 - 1.4e-10 41.3 0.0 2.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY46084.1 - 0.045 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KIY46084.1 - 0.054 12.9 0.1 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_hydro_71 PF03659.14 KIY46085.1 - 6.7e-90 301.6 0.0 2.6e-89 299.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_18 PF00704.28 KIY46086.1 - 6.8e-56 190.3 4.5 8.6e-56 189.9 4.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4849 PF16141.5 KIY46086.1 - 0.0096 15.2 0.2 0.047 12.9 0.0 2.1 2 1 1 3 3 3 1 Putative glycoside hydrolase Family 18, chitinase_18 GHL10 PF02638.15 KIY46086.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Lactonase PF10282.9 KIY46087.1 - 1.7e-48 165.7 0.0 1.9e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ACPS PF01648.20 KIY46088.1 - 0.003 17.7 0.0 0.0046 17.1 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily p450 PF00067.22 KIY46089.1 - 2.6e-52 178.1 0.0 5.7e-52 177.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 YLP PF02757.17 KIY46090.1 - 0.1 12.6 0.2 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 YLP motif Dsh_C PF12316.8 KIY46090.1 - 0.57 10.6 4.1 0.74 10.2 4.1 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SR-25 PF10500.9 KIY46090.1 - 0.77 9.3 19.0 0.061 12.9 13.8 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 KIY46090.1 - 1.3 8.2 3.0 1.1 8.3 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAD_binding_4 PF01565.23 KIY46091.1 - 8.6e-13 48.2 0.1 2.7e-06 27.2 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.12 KIY46091.1 - 7.2e-06 26.0 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 KIY46091.1 - 0.026 14.4 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.10 KIY46091.1 - 0.042 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding PAPA-1 PF04795.12 KIY46092.1 - 2e-22 79.7 7.0 2e-22 79.7 7.0 2.5 2 1 1 3 3 3 1 PAPA-1-like conserved region FCH PF00611.23 KIY46093.1 - 3.9e-13 49.5 0.3 2e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KIY46093.1 - 2.2e-10 40.0 0.0 4.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY46093.1 - 1.5e-08 34.4 0.1 2.9e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY46093.1 - 1.7e-05 24.4 0.0 3.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SOAR PF16533.5 KIY46093.1 - 0.0087 16.0 3.4 0.016 15.1 2.9 1.7 1 1 0 1 1 1 1 STIM1 Orai1-activating region Phi_1 PF04674.12 KIY46093.1 - 0.22 10.8 0.1 0.32 10.3 0.1 1.3 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region p450 PF00067.22 KIY46094.1 - 5.4e-81 272.7 0.0 2.1e-80 270.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 IKI3 PF04762.12 KIY46095.1 - 3.4e-230 766.7 0.0 7.2e-173 577.0 0.0 3.0 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 KIY46095.1 - 3.2e-05 24.1 0.3 22 5.4 0.0 5.8 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Efg1 PF10153.9 KIY46097.1 - 2e-29 102.3 4.7 2e-29 102.3 4.7 1.6 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DNA_alkylation PF08713.11 KIY46097.1 - 0.0012 18.6 0.4 0.0018 18.0 0.4 1.2 1 0 0 1 1 1 1 DNA alkylation repair enzyme DUF4140 PF13600.6 KIY46097.1 - 0.11 12.9 1.2 0.24 11.8 1.2 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MARVEL PF01284.23 KIY46098.1 - 2.6e-12 47.0 9.6 2.6e-12 47.0 9.6 1.4 1 1 0 1 1 1 1 Membrane-associating domain RRM_1 PF00076.22 KIY46099.1 - 7.8e-29 99.3 2.0 6.2e-09 35.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY46099.1 - 8.4e-05 22.6 0.1 0.23 11.5 0.1 2.5 2 0 0 2 2 2 2 RNA binding motif DUF4523 PF15023.6 KIY46099.1 - 0.0022 17.9 0.0 3.1 7.6 0.0 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 KIY46099.1 - 0.0085 15.9 0.0 2.8 7.9 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif Cadherin_tail PF15974.5 KIY46099.1 - 0.019 15.3 3.1 0.05 13.9 3.1 1.7 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region DUF1866 PF08952.11 KIY46099.1 - 0.068 13.0 0.0 5.4 6.9 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1866) RRM_7 PF16367.5 KIY46099.1 - 0.11 12.7 0.0 7.3 6.8 0.0 3.3 4 0 0 4 4 4 0 RNA recognition motif Glyco_hydro_28 PF00295.17 KIY46100.1 - 1.7e-49 168.6 12.1 2.3e-49 168.2 12.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIY46100.1 - 0.012 15.4 14.9 0.039 13.8 14.9 2.0 1 1 0 1 1 1 0 Right handed beta helix region O-FucT PF10250.9 KIY46101.1 - 1.5e-09 38.1 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase FAD_binding_3 PF01494.19 KIY46102.1 - 4.6e-20 72.2 0.1 6.4e-19 68.4 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY46102.1 - 0.00011 22.3 0.3 0.00025 21.2 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY46102.1 - 0.00021 21.0 1.9 0.0018 17.9 0.9 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY46102.1 - 0.0003 20.1 0.2 0.0081 15.4 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY46102.1 - 0.0035 16.1 0.3 0.025 13.3 0.6 1.9 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 KIY46102.1 - 0.0041 16.2 0.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 KIY46102.1 - 0.0042 17.1 1.0 0.67 9.9 0.3 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIY46102.1 - 0.0061 15.7 0.5 0.0098 15.0 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIY46102.1 - 0.079 12.2 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KIY46102.1 - 0.13 12.8 0.1 0.34 11.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY46102.1 - 0.22 10.3 0.7 5.5 5.7 0.1 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KIY46102.1 - 0.82 8.9 2.9 6.2 6.0 3.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BTB PF00651.31 KIY46103.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain RNA_pol_Rpc4 PF05132.14 KIY46105.1 - 5.1e-26 91.9 1.8 5.1e-26 91.9 1.8 2.6 2 1 0 2 2 2 1 RNA polymerase III RPC4 DUF1493 PF07377.12 KIY46105.1 - 0.1 13.0 0.7 0.2 12.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) E1-E2_ATPase PF00122.20 KIY46106.1 - 5.8e-48 162.8 0.1 5.8e-48 162.8 0.1 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIY46106.1 - 2.2e-35 122.0 3.5 2.2e-35 122.0 3.5 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIY46106.1 - 3.4e-17 63.5 3.3 9.5e-17 62.0 3.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY46106.1 - 3.4e-13 49.5 0.0 8.5e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIY46106.1 - 2.7e-09 36.6 0.0 5.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus RseC_MucC PF04246.12 KIY46106.1 - 0.0011 18.9 0.1 0.0011 18.9 0.1 2.6 3 1 1 4 4 4 1 Positive regulator of sigma(E), RseC/MucC Hydrolase_3 PF08282.12 KIY46106.1 - 0.0025 17.6 1.2 0.005 16.6 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY46106.1 - 0.045 14.2 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PGM1_C PF18105.1 KIY46106.1 - 0.13 11.8 0.3 0.49 10.0 0.3 2.0 1 0 0 1 1 1 0 PGM1 C-terminal domain DUF2127 PF09900.9 KIY46106.1 - 0.13 12.5 2.0 0.25 11.6 0.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) DUF4072 PF13284.6 KIY46107.1 - 1 9.9 4.9 0.47 10.9 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) DcpS_C PF11969.8 KIY46108.1 - 2.5e-26 92.4 0.0 4.8e-26 91.5 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KIY46108.1 - 1.2e-06 29.2 0.0 2.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal TEA PF01285.18 KIY46110.1 - 3.4e-17 62.3 0.1 3.9e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 TEA/ATTS domain EutK_C PF16365.5 KIY46111.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Aldo_ket_red PF00248.21 KIY46112.1 - 1.2e-44 152.7 0.3 6.7e-44 150.3 0.3 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family PB1 PF00564.24 KIY46113.1 - 3e-06 27.1 0.0 6.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Clenterotox PF03505.14 KIY46114.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Clostridium enterotoxin PRIMA1 PF16101.5 KIY46114.1 - 0.24 11.5 6.8 0.72 9.9 1.0 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 WD40 PF00400.32 KIY46115.1 - 1.1e-17 64.0 12.5 9.8e-05 23.1 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY46115.1 - 1.9e-14 53.7 1.6 5.5e-05 23.4 0.1 4.3 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY46115.1 - 0.0024 17.8 0.2 0.38 10.6 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIY46115.1 - 0.045 13.1 0.0 0.61 9.4 0.0 2.3 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal GFA PF04828.14 KIY46116.1 - 8.6e-06 26.0 2.0 8.6e-06 26.0 0.1 2.0 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Sugar_tr PF00083.24 KIY46119.1 - 1.2e-108 364.0 21.0 1.4e-108 363.7 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY46119.1 - 6.8e-30 104.2 35.1 1.4e-27 96.6 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY46119.1 - 0.00097 17.7 1.5 0.00097 17.7 1.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIY46120.1 - 5.1e-109 365.1 19.4 6e-109 364.9 19.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY46120.1 - 5.2e-30 104.6 43.3 1.2e-27 96.8 19.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KIY46120.1 - 0.012 14.0 7.1 0.03 12.7 4.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector WD40 PF00400.32 KIY46122.1 - 3.9e-15 56.0 10.5 0.0013 19.5 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY46122.1 - 2.8e-14 53.2 1.2 9.3e-06 25.9 0.1 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY46122.1 - 0.018 15.0 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Receptor_2B4 PF11465.8 KIY46123.1 - 0.13 12.5 0.5 7 6.9 0.1 2.5 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 EF-hand_1 PF00036.32 KIY46125.1 - 4.9e-20 69.5 0.2 1.6e-05 24.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KIY46125.1 - 1.8e-18 64.8 0.2 2.8e-05 23.7 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KIY46125.1 - 1.3e-16 59.2 0.3 0.00013 21.3 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KIY46125.1 - 9.4e-16 58.0 0.6 1e-09 38.7 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KIY46125.1 - 2.8e-15 55.9 0.1 6.2e-10 38.8 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KIY46125.1 - 0.16 12.0 0.3 0.71 9.9 0.2 1.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SET PF00856.28 KIY46126.1 - 7e-16 59.1 0.1 7.4e-15 55.7 0.1 2.3 1 1 0 1 1 1 1 SET domain Sel1 PF08238.12 KIY46126.1 - 0.23 12.2 0.3 0.51 11.1 0.3 1.6 1 0 0 1 1 1 0 Sel1 repeat Complex1_LYR PF05347.15 KIY46128.1 - 0.091 12.8 0.4 0.3 11.2 0.4 1.9 1 0 0 1 1 1 0 Complex 1 protein (LYR family) RTA1 PF04479.13 KIY46129.1 - 3.9e-57 193.2 2.5 1.1e-56 191.8 2.5 1.7 1 1 0 1 1 1 1 RTA1 like protein Uso1_p115_head PF04869.14 KIY46130.1 - 3.7e-44 151.1 0.0 2.2e-35 122.3 0.0 2.3 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KIY46130.1 - 6e-11 42.8 25.1 9.7e-11 42.1 25.1 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region IBN_N PF03810.19 KIY46130.1 - 0.0058 16.5 0.2 5.6 7.0 0.0 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain DUF1640 PF07798.11 KIY46130.1 - 0.0094 16.0 5.6 0.017 15.2 5.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) KASH_CCD PF14662.6 KIY46130.1 - 0.06 13.2 13.9 0.099 12.5 13.9 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CSRNP_N PF16019.5 KIY46130.1 - 0.37 10.7 1.8 0.6 10.0 1.8 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus RRP36 PF06102.12 KIY46130.1 - 1.2 9.1 11.4 2.2 8.2 11.4 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Mo25 PF08569.11 KIY46130.1 - 1.8 7.8 9.2 0.84 8.9 0.1 2.8 3 0 0 3 3 3 0 Mo25-like DUF5401 PF17380.2 KIY46130.1 - 7 4.6 15.4 10 4.1 15.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) CoaE PF01121.20 KIY46131.1 - 2e-61 206.8 0.0 2.5e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KIY46131.1 - 0.00075 20.1 0.2 0.009 16.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KIY46131.1 - 0.02 14.6 0.1 5.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KIY46131.1 - 0.021 15.1 0.0 0.08 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIY46131.1 - 0.095 12.9 0.0 0.22 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain BTD PF09270.10 KIY46131.1 - 0.096 12.9 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain Methyltransf_3 PF01596.17 KIY46132.1 - 9.9e-36 122.9 0.0 1.3e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIY46132.1 - 1.2e-15 58.4 0.0 2.1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY46132.1 - 1.8e-05 24.6 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY46132.1 - 0.00022 21.9 0.0 0.00046 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY46132.1 - 0.0012 18.7 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 KIY46132.1 - 0.0028 17.4 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 KIY46132.1 - 0.0079 16.8 0.0 0.02 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KIY46132.1 - 0.04 13.8 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KIY46132.1 - 0.13 11.5 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 KIY46133.1 - 3.5e-39 134.2 0.0 4.5e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIY46133.1 - 7.2e-18 65.6 0.0 1.4e-17 64.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY46133.1 - 4.9e-12 45.9 0.0 1.4e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY46133.1 - 1.1e-09 38.8 0.0 1.8e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY46133.1 - 1e-07 32.5 0.0 3.1e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KIY46133.1 - 4.5e-06 26.6 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KIY46133.1 - 0.00087 18.9 0.0 0.0016 18.0 0.0 1.4 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 KIY46133.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY46133.1 - 0.0017 17.7 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KIY46133.1 - 0.0072 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 KIY46133.1 - 0.013 15.1 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.12 KIY46133.1 - 0.02 15.7 0.0 0.04 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KIY46133.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 KIY46133.1 - 0.029 14.2 0.0 0.12 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain CmcI PF04989.12 KIY46133.1 - 0.031 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF4392 PF14336.6 KIY46133.1 - 0.086 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) UPF0146 PF03686.13 KIY46133.1 - 0.099 12.5 0.0 0.79 9.6 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0146) TRM PF02005.16 KIY46133.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase UPF0020 PF01170.18 KIY46133.1 - 0.12 12.1 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.17 KIY46134.1 - 4e-40 137.3 0.0 5.2e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIY46134.1 - 1.2e-17 64.9 0.0 7.4e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY46134.1 - 5e-08 32.9 0.0 9.8e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY46134.1 - 9.5e-07 29.4 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY46134.1 - 8.5e-06 26.3 0.0 2.7e-05 24.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KIY46134.1 - 1.4e-05 24.9 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KIY46134.1 - 0.00019 21.0 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KIY46134.1 - 0.00085 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 GCD14 PF08704.10 KIY46134.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CmcI PF04989.12 KIY46134.1 - 0.023 14.4 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase TRM PF02005.16 KIY46134.1 - 0.076 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Ubie_methyltran PF01209.18 KIY46134.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KIY46134.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3439 PF11921.8 KIY46135.1 - 0.21 11.5 1.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Peptidase_M28 PF04389.17 KIY46136.1 - 4.8e-32 111.3 0.0 7.9e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Glyco_hydr_30_2 PF14587.6 KIY46137.1 - 1.4e-08 34.7 0.1 1.6e-08 34.5 0.1 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_cc PF11790.8 KIY46138.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core ETX_MTX2 PF03318.13 KIY46140.1 - 1.5 8.6 16.1 0.096 12.4 9.0 2.1 1 1 2 3 3 3 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 NAD_binding_10 PF13460.6 KIY46141.1 - 1e-09 38.5 0.0 8.3e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KIY46141.1 - 7.1e-05 22.5 0.0 0.0001 22.0 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIY46141.1 - 0.0013 18.2 0.1 0.0053 16.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIY46141.1 - 0.0034 16.6 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KIY46141.1 - 0.029 14.3 0.1 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 KR domain adh_short PF00106.25 KIY46141.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 KIY46141.1 - 0.047 12.7 0.0 0.28 10.2 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIY46141.1 - 0.052 12.9 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1664 PF07889.12 KIY46142.1 - 0.0042 17.1 0.4 0.0088 16.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) KxDL PF10241.9 KIY46142.1 - 0.015 15.5 2.4 0.093 13.0 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein Fib_alpha PF08702.10 KIY46142.1 - 0.026 14.7 2.0 4.7 7.4 0.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 KIY46142.1 - 0.065 12.7 4.1 0.097 12.1 4.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cep57_CLD_2 PF14197.6 KIY46142.1 - 0.066 13.3 11.7 0.18 11.9 8.8 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 T2SSM PF04612.12 KIY46142.1 - 0.1 12.7 5.1 1.4 9.0 0.3 2.4 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Spc7 PF08317.11 KIY46142.1 - 0.12 11.3 6.6 0.21 10.5 6.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KIY46142.1 - 0.12 11.7 4.9 0.2 11.0 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Filament PF00038.21 KIY46142.1 - 0.15 11.6 8.1 0.054 13.1 5.4 1.5 2 0 0 2 2 2 0 Intermediate filament protein DUF4200 PF13863.6 KIY46142.1 - 0.26 11.7 7.3 0.59 10.5 7.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DHR10 PF18595.1 KIY46142.1 - 0.42 10.7 14.1 2.2 8.4 13.2 2.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Bcr-Abl_Oligo PF09036.10 KIY46142.1 - 0.49 10.4 3.0 5.2 7.1 0.2 2.7 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Spc29 PF17082.5 KIY46142.1 - 0.5 10.2 4.4 2.5 7.9 4.5 2.0 1 1 0 1 1 1 0 Spindle Pole Component 29 OmpH PF03938.14 KIY46142.1 - 0.55 10.6 7.8 0.43 10.9 6.1 1.6 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) Sec8_exocyst PF04048.14 KIY46142.1 - 0.55 10.1 2.7 8.9 6.2 0.3 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain V_ATPase_I PF01496.19 KIY46142.1 - 0.71 7.7 2.8 1.1 7.1 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Helo_like_N PF17111.5 KIY46142.1 - 1.2 8.5 5.4 1.8 7.9 0.3 2.4 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins GAS PF13851.6 KIY46142.1 - 1.6 8.1 8.4 2.8 7.2 7.0 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2203 PF09969.9 KIY46142.1 - 1.8 9.3 5.6 14 6.4 0.3 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DASH_Duo1 PF08651.10 KIY46142.1 - 1.8 8.4 5.9 15 5.4 0.1 3.4 4 1 0 4 4 2 0 DASH complex subunit Duo1 DUF724 PF05266.14 KIY46142.1 - 2.7 7.8 6.2 6 6.6 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc24 PF08286.11 KIY46142.1 - 2.8 8.2 8.3 3.8 7.8 1.0 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 KIY46142.1 - 2.9 7.7 9.0 7.3 6.4 2.1 2.6 1 1 1 2 2 2 0 Septum formation initiator HIP1_clath_bdg PF16515.5 KIY46142.1 - 2.9 8.5 13.6 0.24 12.0 2.1 2.8 2 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FUSC PF04632.12 KIY46142.1 - 7.6 4.9 7.4 1.9 6.9 4.3 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Arylsulfotran_2 PF14269.6 KIY46143.1 - 5.8e-37 127.7 0.0 6.8e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY46143.1 - 9.9e-10 37.9 0.0 7.9e-09 34.9 0.0 1.9 1 1 1 2 2 2 1 Arylsulfotransferase (ASST) CS PF04969.16 KIY46144.1 - 8.3e-20 71.6 0.2 1.3e-19 70.9 0.2 1.3 1 0 0 1 1 1 1 CS domain DUF4404 PF14357.6 KIY46144.1 - 0.28 11.8 3.9 2.9 8.6 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) p450 PF00067.22 KIY46145.1 - 2e-63 214.8 0.0 2.9e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3692 PF12469.8 KIY46145.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.0 3 0 0 3 3 3 0 CRISPR-associated protein Amino_oxidase PF01593.24 KIY46146.1 - 2.4e-66 224.9 0.0 3.1e-64 218.0 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY46146.1 - 3.5e-12 46.4 0.7 1.2e-11 44.7 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY46146.1 - 1.4e-05 24.5 0.1 0.0024 17.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY46146.1 - 0.00046 19.7 0.1 0.00084 18.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KIY46146.1 - 0.00086 19.0 3.3 0.0027 17.3 2.2 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY46146.1 - 0.001 18.2 0.3 0.0019 17.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIY46146.1 - 0.0034 16.2 0.0 0.0071 15.1 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KIY46146.1 - 0.0055 16.0 0.7 0.039 13.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY46146.1 - 0.0056 15.8 0.8 0.043 12.9 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIY46146.1 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KIY46146.1 - 0.013 14.8 0.0 0.029 13.6 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KIY46146.1 - 0.026 14.5 0.2 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIY46146.1 - 0.047 14.2 2.3 0.77 10.4 0.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY46146.1 - 0.12 11.5 0.2 4.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 KIY46147.1 - 8.3e-61 206.6 0.2 7.2e-59 200.3 0.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY46147.1 - 1.1e-11 44.7 1.6 2e-11 43.9 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY46147.1 - 5.3e-05 22.6 0.5 0.01 15.1 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY46147.1 - 8e-05 22.2 0.1 0.00027 20.4 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KIY46147.1 - 0.00036 20.2 0.2 0.0062 16.2 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY46147.1 - 0.00094 18.4 0.4 0.0015 17.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIY46147.1 - 0.013 14.3 0.2 0.028 13.1 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 KIY46147.1 - 0.027 13.7 0.2 0.043 13.1 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KIY46147.1 - 0.034 13.4 1.0 0.083 12.1 0.4 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIY46147.1 - 0.039 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KIY46147.1 - 0.16 11.1 0.8 0.3 10.1 0.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KIY46147.1 - 0.26 11.9 2.1 1.9 9.1 0.4 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DIOX_N PF14226.6 KIY46148.1 - 3.6e-14 53.5 0.0 7.4e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY46148.1 - 8.1e-14 51.9 0.0 1.4e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KIY46149.1 - 9.1e-40 136.6 30.2 9.1e-40 136.6 30.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY46149.1 - 0.00028 19.8 0.5 0.00028 19.8 0.5 2.3 2 0 0 2 2 2 1 MFS_1 like family GAS PF13851.6 KIY46150.1 - 0.0039 16.6 6.4 0.0057 16.0 6.4 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF5361 PF17318.2 KIY46150.1 - 0.016 15.4 0.2 0.058 13.6 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5361) ArdA PF07275.11 KIY46150.1 - 0.034 14.8 0.1 0.058 14.0 0.1 1.4 1 1 0 1 1 1 0 Antirestriction protein (ArdA) ZapB PF06005.12 KIY46150.1 - 0.038 14.4 8.5 0.58 10.6 0.2 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Trimer_CC PF08954.11 KIY46150.1 - 0.039 13.5 0.2 0.039 13.5 0.2 2.5 2 0 0 2 2 2 0 Trimerisation motif bZIP_2 PF07716.15 KIY46150.1 - 0.043 13.9 11.9 1.3 9.2 5.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper FUSC PF04632.12 KIY46150.1 - 0.074 11.6 5.4 0.087 11.4 5.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PNPase PF03726.14 KIY46150.1 - 0.65 10.5 6.3 12 6.5 6.3 2.2 1 1 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF724 PF05266.14 KIY46150.1 - 0.84 9.4 5.1 0.5 10.2 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EMP24_GP25L PF01105.24 KIY46150.1 - 1.3 8.9 3.9 23 4.9 1.3 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD CCDC-167 PF15188.6 KIY46150.1 - 3.3 8.1 8.3 9 6.7 6.1 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Aminotran_3 PF00202.21 KIY46152.1 - 3.3e-94 315.8 0.0 4.1e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase_fungal PF17667.1 KIY46153.1 - 2.3e-31 109.0 0.0 2.6e-21 75.9 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase DIOX_N PF14226.6 KIY46154.1 - 7.3e-27 94.5 0.0 1.1e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY46154.1 - 4.4e-17 62.4 0.0 9.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF917 PF06032.12 KIY46155.1 - 1.8e-50 171.7 0.0 2e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF917) DUF4955 PF16315.5 KIY46156.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) DUF1772 PF08592.11 KIY46156.1 - 0.35 11.2 10.7 0.21 11.9 0.8 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) Ank_2 PF12796.7 KIY46157.1 - 1.3e-17 64.2 0.4 6.9e-13 49.0 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY46157.1 - 4.2e-12 45.1 0.2 0.00015 21.9 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KIY46157.1 - 1.7e-11 44.4 2.4 2.6e-05 24.6 0.1 2.8 2 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY46157.1 - 1.3e-09 38.1 0.9 8.3e-05 22.8 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY46157.1 - 1.1e-08 35.2 2.3 0.0013 19.0 0.4 2.6 2 0 0 2 2 2 2 Ankyrin repeat RCDG1 PF15725.5 KIY46157.1 - 0.091 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein ETX_MTX2 PF03318.13 KIY46158.1 - 0.056 13.2 17.9 0.097 12.4 17.1 1.7 1 1 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Glyco_hydr_30_2 PF14587.6 KIY46159.1 - 7.7e-24 85.0 0.0 3.4e-21 76.3 0.0 2.1 1 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_cc PF11790.8 KIY46159.1 - 0.0022 17.6 0.1 0.0055 16.3 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core Methyltransf_3 PF01596.17 KIY46160.1 - 3e-38 131.1 0.0 3.9e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIY46160.1 - 8.8e-16 58.8 0.0 1.7e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY46160.1 - 2.9e-06 27.2 0.0 1.9e-05 24.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY46160.1 - 4.5e-05 24.1 0.0 0.00013 22.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY46160.1 - 0.00021 21.9 0.0 0.00057 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY46160.1 - 0.00034 20.4 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KIY46160.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KIY46160.1 - 0.024 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PNPase_C PF12111.8 KIY46160.1 - 0.044 13.2 0.1 0.082 12.4 0.1 1.4 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal CmcI PF04989.12 KIY46160.1 - 0.15 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase GCD14 PF08704.10 KIY46160.1 - 0.22 11.2 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit NAD_binding_10 PF13460.6 KIY46161.1 - 3.5e-09 36.8 0.0 4e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KIY46161.1 - 1.6e-05 24.6 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KIY46161.1 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIY46161.1 - 0.0011 18.5 0.1 0.0048 16.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIY46161.1 - 0.012 15.6 0.1 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 KR domain 3Beta_HSD PF01073.19 KIY46161.1 - 0.024 13.6 0.0 0.1 11.6 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KIY46161.1 - 0.038 13.4 0.2 0.068 12.6 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KIY46161.1 - 0.091 12.1 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase zf-MYND PF01753.18 KIY46162.1 - 7.3e-10 38.8 15.7 2.2e-09 37.3 15.7 1.9 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.6 KIY46162.1 - 9.9e-09 35.3 0.1 2.6e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) RVT_1 PF00078.27 KIY46165.1 - 1.5e-07 31.1 0.0 2.8e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRKCSH-like PF12999.7 KIY46166.1 - 0.92 9.3 5.9 0.79 9.5 5.0 1.3 1 1 0 1 1 1 0 Glucosidase II beta subunit-like zf-RVT PF13966.6 KIY46167.1 - 3.8e-10 40.3 0.6 6.2e-10 39.7 0.6 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF4025 PF13217.6 KIY46167.1 - 0.00011 21.9 1.3 0.00018 21.3 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4025) Nudix_N_2 PF14803.6 KIY46167.1 - 0.087 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Nudix N-terminal FERM_f0 PF16511.5 KIY46167.1 - 0.11 12.8 0.1 0.64 10.4 0.1 2.0 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM CCAP PF11105.8 KIY46167.1 - 0.12 12.4 0.8 5.2 7.0 0.4 2.4 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a RPA_interact_C PF14768.6 KIY46168.1 - 0.0012 19.4 0.2 0.0014 19.1 0.2 1.1 1 0 0 1 1 1 1 Replication protein A interacting C-terminal DUF3054 PF11255.8 KIY46169.1 - 0.017 15.7 5.3 0.024 15.2 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) AA_permease_2 PF13520.6 KIY46169.1 - 0.045 12.6 6.1 0.056 12.3 6.1 1.0 1 0 0 1 1 1 0 Amino acid permease MPC PF03650.13 KIY46170.1 - 3.5e-38 130.1 0.5 3.9e-38 130.0 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Tetraspanin PF00335.20 KIY46171.1 - 2.4e-05 24.2 12.5 2.4e-05 24.2 12.5 1.7 1 1 1 2 2 2 1 Tetraspanin family DUF2569 PF10754.9 KIY46171.1 - 0.00026 21.4 10.2 0.017 15.6 5.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2569) Kei1 PF08552.11 KIY46171.1 - 0.041 13.8 0.1 0.041 13.8 0.1 2.5 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 SID-1_RNA_chan PF13965.6 KIY46171.1 - 0.1 11.0 6.5 0.14 10.5 6.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2615 PF11027.8 KIY46171.1 - 0.33 11.1 1.3 0.42 10.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Jagunal PF07086.12 KIY46171.1 - 0.35 10.9 6.7 0.43 10.6 5.2 1.8 1 1 1 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF420 PF04238.12 KIY46171.1 - 0.82 10.0 8.5 1.5 9.1 8.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF420) DUF4199 PF13858.6 KIY46171.1 - 5.5 7.4 14.0 10 6.5 14.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) TssN PF17555.2 KIY46171.1 - 5.7 6.2 11.8 1.8 7.9 7.5 1.8 1 1 1 2 2 2 0 Type VI secretion system, TssN DUF3421 PF11901.8 KIY46172.1 - 2.2e-29 101.8 0.3 1.3e-24 86.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) LRR_4 PF12799.7 KIY46176.1 - 0.47 11.0 8.1 38 4.9 0.3 5.2 4 3 3 7 7 7 0 Leucine Rich repeats (2 copies) Methyltransf_22 PF13383.6 KIY46177.1 - 7.3e-23 81.4 0.1 1.2e-22 80.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KIY46177.1 - 7.9e-07 29.3 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Hexapep PF00132.24 KIY46178.1 - 1.6e-10 40.3 19.4 2e-07 30.5 1.8 4.6 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KIY46178.1 - 3.1e-07 30.0 8.4 0.0012 18.5 0.1 4.0 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KIY46178.1 - 0.0044 16.0 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase TMEM70 PF06979.12 KIY46179.1 - 0.00038 20.9 0.9 0.00046 20.6 0.9 1.2 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex DUF563 PF04577.14 KIY46180.1 - 6e-18 65.7 0.1 3.8e-17 63.1 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF563) Palm_thioest PF02089.15 KIY46181.1 - 4.7e-83 278.7 0.0 5.6e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KIY46181.1 - 0.00034 20.4 0.2 0.0077 15.9 0.0 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold DUF915 PF06028.11 KIY46181.1 - 0.028 13.8 0.0 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) ABC_membrane PF00664.23 KIY46182.1 - 6.9e-47 160.4 29.7 9.7e-25 87.7 8.6 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY46182.1 - 3.2e-44 150.8 0.0 8.3e-27 94.4 0.0 3.0 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY46182.1 - 8.6e-12 45.0 5.1 0.00044 19.7 0.4 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY46182.1 - 2e-07 31.6 0.1 0.012 16.0 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KIY46182.1 - 5.8e-07 29.3 0.3 0.035 13.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KIY46182.1 - 5.9e-06 26.9 2.4 0.00018 22.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KIY46182.1 - 1.5e-05 24.6 0.2 0.013 15.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY46182.1 - 5.9e-05 23.0 5.6 0.026 14.3 0.3 4.2 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KIY46182.1 - 0.00033 19.8 5.0 0.0047 16.0 0.0 3.1 2 1 1 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 KIY46182.1 - 0.0008 19.7 0.4 0.81 10.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY46182.1 - 0.001 18.6 0.0 0.91 9.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DEAD PF00270.29 KIY46182.1 - 0.0014 18.4 0.3 2.1 8.1 0.1 3.6 3 1 0 3 3 3 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 KIY46182.1 - 0.0017 18.4 0.3 0.74 9.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY46182.1 - 0.0021 18.0 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 KIY46182.1 - 0.004 17.3 1.7 0.075 13.1 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain Adeno_IVa2 PF02456.15 KIY46182.1 - 0.019 13.8 0.4 0.079 11.7 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.6 KIY46182.1 - 0.025 15.1 0.0 5.8 7.5 0.0 3.2 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY46182.1 - 0.028 13.8 0.2 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 KIY46182.1 - 0.029 13.9 1.6 0.38 10.3 0.3 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KIY46182.1 - 0.031 14.3 0.1 19 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KIY46182.1 - 0.032 14.0 0.5 16 5.2 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KIY46182.1 - 0.061 13.2 0.6 0.59 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 KIY46182.1 - 0.062 13.3 0.6 7.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 KIY46182.1 - 0.066 12.9 0.4 2.5 7.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KIY46182.1 - 0.086 13.3 0.5 3.1 8.2 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KIY46182.1 - 0.1 12.3 0.3 0.54 10.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 KIY46182.1 - 0.14 11.6 0.8 10 5.5 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein ResIII PF04851.15 KIY46182.1 - 0.15 12.1 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 KIY46182.1 - 0.17 11.6 0.1 23 4.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIY46182.1 - 0.2 11.6 0.7 5.4 6.9 0.2 2.6 2 0 0 2 2 2 0 NACHT domain Hamartin PF04388.12 KIY46182.1 - 2.7 6.5 4.0 4.2 5.9 4.0 1.1 1 0 0 1 1 1 0 Hamartin protein COX7C PF02935.16 KIY46183.1 - 2e-12 47.2 1.3 2.2e-12 47.0 1.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc HSP70 PF00012.20 KIY46184.1 - 2.8e-262 871.3 13.0 3.2e-262 871.1 13.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY46184.1 - 5e-15 55.2 3.1 6.4e-13 48.2 0.8 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KIY46184.1 - 0.00057 19.7 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KIY46184.1 - 0.0068 16.8 7.2 0.74 10.3 0.1 4.0 3 2 0 3 3 3 2 Cell division protein FtsA DUF4344 PF14247.6 KIY46184.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase DMRL_synthase PF00885.19 KIY46184.1 - 0.092 12.6 0.3 0.57 10.0 0.1 2.2 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Pantoate_transf PF02548.15 KIY46185.1 - 7e-106 353.4 0.5 8.2e-106 353.1 0.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KIY46185.1 - 1e-06 28.4 0.2 1.7e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APH PF01636.23 KIY46186.1 - 1.5e-35 123.2 0.0 2.1e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY46186.1 - 4.7e-06 26.3 0.0 1.2e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KIY46186.1 - 6.4e-05 22.4 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KIY46186.1 - 0.0025 16.8 0.0 0.0056 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Acetyltransf_10 PF13673.7 KIY46188.1 - 3.2e-08 33.6 0.0 4.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY46188.1 - 2.1e-07 30.8 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KIY46188.1 - 1.1e-06 28.8 0.1 1.8e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY46188.1 - 3.7e-06 27.3 0.1 6.7e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY46188.1 - 0.00014 21.9 0.0 0.00044 20.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIY46188.1 - 0.0041 17.8 0.0 0.0076 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIY46188.1 - 0.068 13.2 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KIY46188.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Abhydrolase_3 PF07859.13 KIY46189.1 - 5.7e-38 130.9 0.0 1.5e-32 113.2 0.0 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY46189.1 - 5e-08 32.2 0.0 9.4e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase CortBP2 PF09727.9 KIY46189.1 - 0.62 9.9 3.0 0.2 11.5 0.2 1.6 2 0 0 2 2 2 0 Cortactin-binding protein-2 Foie-gras_1 PF11817.8 KIY46190.1 - 5.4e-37 127.8 2.7 3.1e-34 118.7 1.6 3.1 2 1 0 2 2 2 1 Foie gras liver health family 1 TPR_12 PF13424.6 KIY46190.1 - 0.019 15.2 6.6 0.14 12.4 1.9 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY46190.1 - 0.031 14.2 0.1 1.2 9.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Gryzun-like PF12742.7 KIY46190.1 - 0.07 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TPR_7 PF13176.6 KIY46190.1 - 0.25 11.5 2.2 0.51 10.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY46190.1 - 0.35 11.4 1.0 1.5 9.4 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY46190.1 - 2.1 8.7 9.2 0.83 9.9 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TRI5 PF06330.11 KIY46191.1 - 2.4e-10 39.8 0.0 2.7e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Pkinase PF00069.25 KIY46192.1 - 4.1e-65 219.8 0.0 4.9e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46192.1 - 4.8e-32 111.3 0.0 6.5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY46192.1 - 0.073 12.0 0.2 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KIY46193.1 - 6.8e-56 189.5 0.0 1.7e-40 139.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46193.1 - 3.5e-24 85.5 0.0 1.4e-23 83.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY46193.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY46193.1 - 0.00019 20.5 0.1 0.00066 18.7 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KIY46193.1 - 0.0002 20.8 0.3 0.00033 20.1 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY46193.1 - 0.0002 21.4 0.3 0.00031 20.7 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY46193.1 - 0.00096 18.0 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KIY46193.1 - 0.013 15.2 0.0 0.061 13.0 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cyclase PF04199.13 KIY46194.1 - 7.3e-28 97.5 0.1 1e-27 97.1 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase NMD3 PF04981.13 KIY46195.1 - 3.8e-79 265.6 0.3 5e-79 265.2 0.3 1.1 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KIY46195.1 - 0.1 12.6 7.2 1.9 8.6 1.1 2.6 1 1 1 2 2 2 0 Double zinc ribbon NinF PF05810.12 KIY46195.1 - 0.16 11.9 0.5 0.57 10.1 0.2 2.1 3 0 0 3 3 3 0 NinF protein Rpr2 PF04032.16 KIY46195.1 - 0.43 10.9 4.0 11 6.4 0.2 3.0 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain MMR_HSR1_Xtn PF16897.5 KIY46196.1 - 1.5e-40 137.5 0.9 2.8e-40 136.6 0.9 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KIY46196.1 - 3.1e-19 69.2 0.1 6e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KIY46196.1 - 2.5e-17 62.6 0.0 4.6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KIY46196.1 - 1.2e-10 41.2 0.0 2.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KIY46196.1 - 0.025 14.0 0.2 0.087 12.2 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KIY46196.1 - 0.029 14.4 0.1 0.63 10.1 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.6 KIY46196.1 - 0.081 13.3 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 KIY46196.1 - 0.094 12.9 0.1 0.85 9.8 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_C2 PF00648.21 KIY46197.1 - 4.4e-62 209.8 0.3 2.2e-61 207.5 0.3 1.8 1 1 0 1 1 1 1 Calpain family cysteine protease Glyco_hydro_31 PF01055.26 KIY46198.1 - 7.2e-141 470.4 4.1 1.2e-140 469.6 4.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIY46198.1 - 2.3e-18 66.3 0.1 6.7e-18 64.8 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KIY46198.1 - 2.6e-07 30.8 0.0 8e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Gb3_synth PF04572.12 KIY46198.1 - 0.074 13.2 0.4 0.17 12.1 0.2 1.7 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region DUF572 PF04502.13 KIY46199.1 - 4.2e-67 227.1 0.9 4.5e-67 227.0 0.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DNA_ligase_A_N PF04675.14 KIY46200.1 - 0.087 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 DNA ligase N terminus NKAIN PF05640.14 KIY46201.1 - 0.0033 16.7 0.2 0.041 13.1 0.1 2.0 1 1 1 2 2 2 1 Na,K-Atpase Interacting protein DUF2997 PF11211.8 KIY46201.1 - 0.2 11.5 0.0 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) Robl_LC7 PF03259.17 KIY46203.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain CI-B14_5a PF07347.12 KIY46204.1 - 0.0016 18.3 0.1 0.0028 17.5 0.0 1.5 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Lactamase_B PF00753.27 KIY46205.1 - 7.5e-18 65.2 1.4 1.2e-17 64.6 1.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIY46205.1 - 7e-08 32.2 0.2 1e-07 31.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PI3_PI4_kinase PF00454.27 KIY46206.1 - 2.4e-37 129.1 0.0 4.2e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RRM_1 PF00076.22 KIY46207.1 - 6.5e-13 48.3 0.0 3.9e-05 23.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY46207.1 - 0.015 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Mito_carr PF00153.27 KIY46208.1 - 1.7e-63 210.6 1.8 7.7e-22 77.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KIY46209.1 - 2e-39 132.8 34.9 1.4e-06 28.9 0.1 8.8 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 KIY46209.1 - 1.5e-11 43.8 0.3 4e-11 42.5 0.2 1.8 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY46209.1 - 7.5e-11 41.8 0.3 7.5e-11 41.8 0.3 1.9 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KIY46209.1 - 0.00036 20.8 1.3 5.7 7.3 0.0 4.7 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KIY46209.1 - 0.0014 18.5 0.3 0.0078 16.1 0.0 2.5 2 0 0 2 2 2 1 F-box Nup160 PF11715.8 KIY46209.1 - 0.0069 15.1 11.8 2.7 6.5 0.0 4.9 2 2 1 4 4 4 2 Nucleoporin Nup120/160 Mnd1 PF03962.15 KIY46210.1 - 1.6e-24 86.0 0.2 2.9e-24 85.1 0.2 1.5 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KIY46210.1 - 2.5e-08 33.9 0.0 8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Fungal_trans PF04082.18 KIY46211.1 - 8.5e-08 31.5 0.1 1.6e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY46211.1 - 2.1e-07 30.9 12.2 3.5e-07 30.2 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PP2C PF00481.21 KIY46212.1 - 1.2e-62 211.9 0.6 3.4e-48 164.5 0.3 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KIY46212.1 - 0.00084 19.3 0.5 0.0022 17.9 0.2 1.9 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) IU_nuc_hydro PF01156.19 KIY46213.1 - 2.9e-40 138.7 0.0 3.8e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase W2 PF02020.18 KIY46214.1 - 3e-18 65.7 2.3 3.3e-17 62.4 0.1 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Stork_head PF10264.9 KIY46214.1 - 0.013 15.7 0.2 0.19 11.9 0.0 2.8 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain TetR PF13972.6 KIY46214.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial transcriptional repressor SLAC1 PF03595.17 KIY46215.1 - 4.9e-70 236.3 53.3 5.7e-70 236.1 53.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Lactamase_B_2 PF12706.7 KIY46216.1 - 1.2e-10 41.2 1.1 9.2e-05 22.0 0.1 3.4 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KIY46216.1 - 2.6e-09 36.6 0.0 6.1e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 KIY46216.1 - 0.036 14.1 0.1 0.097 12.7 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Mito_carr PF00153.27 KIY46218.1 - 2.9e-37 126.5 1.3 7.7e-13 48.2 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein 3HCDH_N PF02737.18 KIY46219.1 - 1.7e-47 161.6 0.4 1.2e-46 158.8 0.4 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KIY46219.1 - 5.4e-34 116.7 0.0 1.2e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF2680 PF10925.8 KIY46219.1 - 0.034 14.1 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) DAO PF01266.24 KIY46219.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 KIY46219.1 - 0.13 12.5 0.2 0.25 11.6 0.2 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain tRNA_anti-codon PF01336.25 KIY46220.1 - 0.0088 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Peptidase_S8 PF00082.22 KIY46221.1 - 1e-34 120.2 14.2 1.8e-34 119.4 14.0 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 KIY46221.1 - 1.7e-10 41.4 0.0 4.8e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sld7_C PF18596.1 KIY46222.1 - 1.2e-05 25.3 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Sld7 C-terminal domain DUF4597 PF15366.6 KIY46222.1 - 5.4 6.8 5.8 2 8.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Dimer_Tnp_hAT PF05699.14 KIY46223.1 - 0.0022 17.7 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region XRN1_D1 PF18332.1 KIY46224.1 - 3.1e-45 154.3 0.0 5.5e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KIY46224.1 - 1.3e-31 108.6 0.1 3.1e-31 107.4 0.1 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KIY46224.1 - 1.2e-22 79.8 0.1 2.3e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KIY46224.1 - 0.0011 19.1 1.2 0.0018 18.3 0.5 1.7 2 0 0 2 2 2 1 Exoribonuclease 1 Domain-3 Borrelia_REV PF03978.13 KIY46224.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Dymeclin PF09742.9 KIY46225.1 - 0.0037 15.8 0.2 0.0057 15.1 0.2 1.3 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein AAA_16 PF13191.6 KIY46225.1 - 0.02 15.3 0.5 0.12 12.8 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain ELFV_dehydrog PF00208.21 KIY46227.1 - 2.4e-48 165.0 0.0 2.9e-40 138.5 0.0 2.5 3 0 0 3 3 3 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KIY46227.1 - 1.8e-14 52.3 0.0 2.6e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Pyr_redox_2 PF07992.14 KIY46228.1 - 1.2e-48 165.9 0.1 1.4e-48 165.7 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY46228.1 - 2.2e-17 63.4 0.2 3e-14 53.3 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY46228.1 - 2.2e-17 63.3 0.2 4.1e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY46228.1 - 2.8e-06 26.7 0.1 1.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KIY46228.1 - 9.5e-06 24.9 1.8 0.0029 16.7 0.1 3.8 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIY46228.1 - 0.00011 22.3 0.3 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY46228.1 - 0.00014 21.1 3.0 0.0031 16.7 0.3 2.8 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 KIY46228.1 - 0.00016 21.3 1.1 0.41 10.2 0.3 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIY46228.1 - 0.00028 20.4 0.1 0.0058 16.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIY46228.1 - 0.00038 20.9 0.2 0.13 12.7 0.0 3.4 3 2 0 3 3 3 1 Putative NAD(P)-binding K_oxygenase PF13434.6 KIY46228.1 - 0.0027 16.9 0.2 0.32 10.1 0.0 3.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KIY46228.1 - 0.0036 17.4 0.6 6.8 6.8 0.0 3.6 3 1 1 4 4 4 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KIY46228.1 - 0.0045 16.3 0.2 0.075 12.3 0.0 2.4 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KIY46228.1 - 0.033 12.9 1.7 0.077 11.7 0.4 2.2 3 0 0 3 3 3 0 HI0933-like protein F420_oxidored PF03807.17 KIY46228.1 - 0.042 14.4 0.0 1.3 9.6 0.0 3.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 KIY46228.1 - 0.058 12.2 0.3 0.22 10.4 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 KIY46228.1 - 0.092 12.4 0.5 9 5.9 0.0 2.8 3 1 0 3 3 3 0 Ketopantoate reductase PanE/ApbA APH PF01636.23 KIY46229.1 - 2e-12 47.6 0.1 1.8e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY46229.1 - 2.5e-05 24.0 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KIY46229.1 - 0.0003 20.2 0.0 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 KIY46229.1 - 0.00071 19.2 0.0 0.0017 18.0 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 KIY46229.1 - 0.0021 17.4 0.0 0.0062 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KIY46229.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY46229.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain EcKinase PF02958.20 KIY46229.1 - 0.031 13.6 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase SIR2 PF02146.17 KIY46230.1 - 1.1e-32 113.3 0.0 2.8e-32 112.0 0.0 1.7 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KIY46230.1 - 0.098 12.4 0.0 8.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain S10_plectin PF03501.15 KIY46231.1 - 3.5e-44 148.8 0.1 4.4e-44 148.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 KIY46231.1 - 0.12 12.3 0.0 0.54 10.2 0.0 2.0 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Nipped-B_C PF12830.7 KIY46232.1 - 1.1e-48 165.7 0.8 2.9e-48 164.3 0.8 1.8 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KIY46232.1 - 3.6e-16 59.2 0.6 3.6e-16 59.2 0.6 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KIY46232.1 - 2.5e-05 24.7 4.7 0.25 11.9 0.6 5.4 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KIY46232.1 - 0.00011 22.5 0.9 0.00011 22.5 0.9 4.1 4 1 1 5 5 5 1 HEAT repeats Adaptin_N PF01602.20 KIY46232.1 - 0.00022 19.9 0.5 0.00089 17.9 0.0 2.1 2 0 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.22 KIY46232.1 - 0.00071 19.6 4.1 0.18 12.1 0.0 4.4 5 0 0 5 5 2 1 HEAT repeat SIL1 PF16782.5 KIY46232.1 - 0.014 14.6 0.1 0.099 11.8 0.0 2.2 3 0 0 3 3 3 0 Nucleotide exchange factor SIL1 PMC2NT PF08066.12 KIY46232.1 - 0.082 13.6 1.2 59 4.4 0.1 3.9 3 0 0 3 3 3 0 PMC2NT (NUC016) domain DUF5472 PF17566.2 KIY46232.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5472) Cnd1 PF12717.7 KIY46232.1 - 0.14 12.2 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Med3 PF11593.8 KIY46232.1 - 7.6 5.6 5.6 9.9 5.2 0.3 2.9 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal KDZ PF18758.1 KIY46235.1 - 5.9e-06 26.1 0.2 7.2e-06 25.8 0.2 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIY46236.1 - 1.2e-63 214.7 1.4 2e-63 214.0 1.4 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase NleF_casp_inhib PF16809.5 KIY46236.1 - 0.069 13.1 0.6 0.13 12.2 0.6 1.4 1 0 0 1 1 1 0 NleF caspase inhibitor SepF PF04472.12 KIY46238.1 - 0.044 14.1 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 Cell division protein SepF Cyt-b5 PF00173.28 KIY46239.1 - 0.013 15.6 0.3 0.065 13.4 0.1 2.2 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain YscO PF07321.12 KIY46239.1 - 0.03 14.3 0.6 0.03 14.3 0.6 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO NIF PF03031.18 KIY46240.1 - 4.2e-39 133.8 0.0 6.2e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Retrotran_gag_2 PF14223.6 KIY46241.1 - 1.1e-06 28.4 0.2 2.1e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2750 PF11042.8 KIY46245.1 - 0.014 15.5 0.1 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) Actin PF00022.19 KIY46247.1 - 6.6e-145 482.8 0.0 3.7e-144 480.3 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 KIY46247.1 - 0.17 10.4 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase US10 PF17617.2 KIY46250.1 - 0.057 13.5 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral unique short region 10 SDA1 PF05285.12 KIY46251.1 - 2.8 7.3 14.1 4.5 6.6 14.1 1.3 1 0 0 1 1 1 0 SDA1 PGA2 PF07543.12 KIY46252.1 - 2 8.4 5.6 6.9 6.6 4.3 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 p450 PF00067.22 KIY46253.1 - 1.4e-07 30.7 0.0 2.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 KIY46254.1 - 6.4e-30 102.9 4.0 1.2e-15 57.1 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KIY46255.1 - 8.7e-36 123.6 49.5 9.7e-35 120.1 49.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY46255.1 - 1.3e-08 33.8 12.0 1.9e-08 33.2 12.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.6 KIY46255.1 - 0.11 13.0 6.5 0.2 12.1 0.1 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) Pyr_redox_2 PF07992.14 KIY46256.1 - 2e-29 102.8 0.0 2.8e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY46256.1 - 8.9e-11 42.2 0.0 1.7e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KIY46256.1 - 0.00036 20.8 0.1 0.0017 18.6 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 KIY46256.1 - 0.014 15.0 0.1 7.3 6.1 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase tRNA_int_end_N2 PF12928.7 KIY46259.1 - 1.3e-21 76.5 0.0 2.4e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KIY46259.1 - 0.0015 18.2 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Shugoshin_C PF07557.11 KIY46260.1 - 6.1e-10 38.7 4.2 6.1e-10 38.7 4.2 3.4 2 0 0 2 2 2 1 Shugoshin C terminus Shugoshin_N PF07558.11 KIY46260.1 - 8.4e-09 35.2 4.5 1.7e-08 34.2 4.5 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region HAUS-augmin3 PF14932.6 KIY46260.1 - 0.18 11.3 3.0 0.079 12.5 0.4 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 KIY46260.1 - 2.2 9.0 5.6 1.2 9.8 3.3 1.7 2 0 0 2 2 2 0 Initiation control protein YabA DUF3496 PF12001.8 KIY46260.1 - 9.1 6.7 10.4 16 5.9 1.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3496) Inositol_P PF00459.25 KIY46261.1 - 5.3e-66 222.9 0.0 6.1e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Iso_dh PF00180.20 KIY46263.1 - 9.5e-34 117.1 0.0 4.6e-32 111.5 0.0 2.2 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_integrase PF00589.22 KIY46264.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family HSF_DNA-bind PF00447.17 KIY46267.1 - 1.1e-29 102.9 0.9 1.2e-29 102.7 0.9 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Acyltransferase PF01553.21 KIY46268.1 - 5.8e-13 48.6 0.0 4.1e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Glyco_hydro_88 PF07470.13 KIY46269.1 - 9.3e-15 54.5 0.2 1.3e-14 54.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF2066 PF09839.9 KIY46271.1 - 0.23 10.8 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) FGGY_C PF02782.16 KIY46272.1 - 4.9e-47 160.2 0.1 6.8e-47 159.8 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KIY46272.1 - 3.6e-20 72.6 0.1 4.6e-18 65.7 0.0 2.7 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KIY46272.1 - 0.00017 21.2 0.4 0.13 11.8 0.1 2.4 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.21 KIY46272.1 - 0.0016 18.4 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Hexokinase BTB PF00651.31 KIY46273.1 - 8.3e-06 26.0 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Se-cys_synth_N PF12390.8 KIY46273.1 - 0.025 14.8 0.6 1.3 9.4 0.1 2.5 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Aldedh PF00171.22 KIY46274.1 - 3.7e-33 114.7 0.0 4e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pirin PF02678.16 KIY46275.1 - 0.0037 17.2 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Pirin KDZ PF18758.1 KIY46277.1 - 7.3e-05 22.5 0.0 7.3e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase DUF4939 PF16297.5 KIY46283.1 - 0.048 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Retrotran_gag_2 PF14223.6 KIY46285.1 - 5.4e-11 42.3 0.5 1.4e-06 28.0 0.1 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type PSK_trans_fac PF07704.11 KIY46285.1 - 0.022 15.5 0.1 1.8 9.4 0.0 2.3 2 0 0 2 2 2 0 Rv0623-like transcription factor Dimer_Tnp_hAT PF05699.14 KIY46286.1 - 3e-06 26.9 0.3 0.00061 19.5 0.1 2.6 2 1 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIY46286.1 - 0.0059 16.9 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Exo_endo_phos PF03372.23 KIY46288.1 - 0.0044 16.6 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 KIY46289.1 - 2.8e-05 23.8 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PGM_PMM_III PF02880.16 KIY46289.1 - 0.037 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III zf-RVT PF13966.6 KIY46290.1 - 3.3e-09 37.3 0.3 3.3e-09 37.3 0.3 2.8 2 1 1 3 3 3 1 zinc-binding in reverse transcriptase HLH PF00010.26 KIY46291.1 - 1.4e-11 44.2 2.3 4.5e-11 42.5 0.5 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain LPD34 PF18852.1 KIY46291.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 TBCA PF02970.16 KIY46293.1 - 1.6e-20 73.2 2.7 1.9e-20 73.0 2.7 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Med11 PF10280.9 KIY46294.1 - 7.2e-06 26.5 0.1 1.1e-05 26.0 0.1 1.4 1 1 0 1 1 1 1 Mediator complex protein Sec1 PF00995.23 KIY46295.1 - 3.3e-115 386.5 0.0 3.7e-115 386.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family YABBY PF04690.13 KIY46296.1 - 1.2e-10 42.2 1.3 1.3e-10 42.1 1.3 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.10 KIY46296.1 - 0.0004 20.9 0.5 0.0004 20.9 0.5 1.4 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 KIY46296.1 - 0.00042 20.7 0.6 0.0006 20.2 0.6 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box Ccdc124 PF06244.12 KIY46296.1 - 0.0048 17.5 1.1 0.0055 17.3 1.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 VEK-30 PF12107.8 KIY46296.1 - 0.052 13.5 0.2 0.081 12.9 0.2 1.3 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway DUF3383 PF11863.8 KIY46298.1 - 0.023 13.8 0.2 0.031 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) SKN1 PF03935.15 KIY46300.1 - 2.6e-182 606.7 5.9 3.1e-182 606.5 5.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Chitin_synth_1 PF01644.17 KIY46301.1 - 1.5e-69 233.1 0.0 2.2e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIY46301.1 - 9e-28 96.0 0.0 2.8e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIY46301.1 - 1.6e-20 73.2 0.0 5.8e-19 68.1 0.0 2.3 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY46301.1 - 2.7e-05 24.2 10.1 0.00021 21.3 10.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIY46301.1 - 0.036 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pkinase PF00069.25 KIY46302.1 - 5.2e-27 94.9 0.0 6.4e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46302.1 - 4.4e-14 52.4 0.0 5.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY46302.1 - 2.2e-09 36.6 0.1 3e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY46302.1 - 0.0011 19.0 0.0 0.0067 16.4 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIY46302.1 - 0.019 13.9 0.1 0.028 13.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KIY46302.1 - 0.075 12.4 0.6 0.11 11.9 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homeodomain PF00046.29 KIY46303.1 - 1.5e-47 159.2 18.9 4.4e-16 58.5 2.1 3.5 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 KIY46303.1 - 1.2e-11 44.3 8.7 0.00047 20.0 0.1 4.3 4 0 0 4 4 4 3 Homeobox KN domain YdaS_antitoxin PF15943.5 KIY46303.1 - 1.5e-07 31.1 0.7 0.3 11.0 0.1 3.4 3 0 0 3 3 3 3 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KIY46303.1 - 1.7e-05 24.8 0.8 0.75 9.9 0.0 3.4 3 0 0 3 3 3 2 Helix-turn-helix Homez PF11569.8 KIY46303.1 - 0.00079 18.8 2.2 5.4 6.6 0.0 4.1 4 0 0 4 4 4 1 Homeodomain leucine-zipper encoding, Homez HTH_26 PF13443.6 KIY46303.1 - 0.0045 17.4 0.9 7.7 7.0 0.1 3.4 3 0 0 3 3 3 1 Cro/C1-type HTH DNA-binding domain Sigma70_r4_2 PF08281.12 KIY46303.1 - 0.005 16.5 0.2 6 6.6 0.0 3.4 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 KIY46303.1 - 0.0078 16.0 0.1 1.9 8.4 0.0 3.7 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain DUF4332 PF14229.6 KIY46303.1 - 0.0082 16.4 4.7 5 7.4 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4332) HTH_Tnp_ISL3 PF13542.6 KIY46303.1 - 0.016 14.6 0.1 44 3.6 0.0 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Terminase_5 PF06056.12 KIY46303.1 - 0.028 14.3 5.5 3.7 7.5 0.0 3.5 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) Phage_CI_repr PF07022.13 KIY46303.1 - 0.039 14.0 0.0 13 5.9 0.0 2.9 3 0 0 3 3 3 0 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 KIY46303.1 - 0.057 13.0 0.0 15 5.2 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KIY46303.1 - 0.11 12.5 0.0 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HOCHOB PF17943.1 KIY46303.1 - 0.12 13.1 0.0 3.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox DUF4207 PF13904.6 KIY46303.1 - 1.7 8.2 13.0 1.5 8.4 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) Choline_transpo PF04515.12 KIY46304.1 - 1.5e-46 159.1 5.7 1.5e-46 159.1 5.7 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Caveolin PF01146.17 KIY46304.1 - 2.1 8.3 6.0 8.8 6.3 6.0 2.0 1 0 0 1 1 1 0 Caveolin Adaptin_N PF01602.20 KIY46305.1 - 3.4e-113 379.0 0.0 4.3e-113 378.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KIY46305.1 - 9.6e-56 188.1 0.2 2.3e-55 186.9 0.2 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KIY46305.1 - 3.5e-35 120.6 0.0 9.9e-35 119.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KIY46305.1 - 6.3e-20 71.4 2.4 1.3e-09 38.3 0.0 6.2 2 2 4 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KIY46305.1 - 8.9e-08 32.3 4.7 0.12 12.4 0.0 4.5 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIY46305.1 - 0.0016 18.5 6.5 58 4.3 0.0 6.5 7 0 0 7 7 7 0 HEAT repeat DUF5010 PF16402.5 KIY46305.1 - 0.14 10.9 0.0 0.37 9.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT_PBS PF03130.16 KIY46305.1 - 0.15 12.8 1.8 32 5.6 0.0 5.3 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Fumble PF03630.14 KIY46306.1 - 2.9e-126 421.1 0.0 3.7e-126 420.8 0.0 1.1 1 0 0 1 1 1 1 Fumble Pkinase PF00069.25 KIY46307.1 - 4.2e-19 68.9 0.0 5.3e-10 39.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.25 KIY46308.1 - 8.1e-33 113.9 0.0 1.1e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46308.1 - 3.5e-10 39.6 0.0 6e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KIY46308.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KIY46308.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KIY46309.1 - 1.7e-29 103.0 0.0 6.3e-17 61.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46309.1 - 2.7e-07 30.2 0.0 4e-06 26.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY46309.1 - 0.013 14.8 0.0 3.6 6.8 0.0 2.5 2 1 1 3 3 3 0 Kinase-like Pkinase_fungal PF17667.1 KIY46309.1 - 0.015 14.1 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KIY46309.1 - 0.16 11.9 0.5 2.5 8.0 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family ICL PF00463.21 KIY46310.1 - 6.6e-188 625.5 0.1 7.5e-188 625.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KIY46310.1 - 1.3e-09 37.8 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PapA_C PF16911.5 KIY46310.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus cNMP_binding PF00027.29 KIY46312.1 - 5.2e-29 100.2 0.0 1e-15 57.5 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KIY46312.1 - 2.4e-15 57.2 4.7 9e-12 45.6 2.8 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase NCBP3 PF10309.9 KIY46315.1 - 2.9e-06 27.0 0.0 4.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KIY46315.1 - 0.00033 20.6 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain SIKE PF05769.11 KIY46316.1 - 6.9e-11 42.4 15.9 2.9e-07 30.6 11.1 3.0 2 1 1 3 3 3 2 SIKE family SlyX PF04102.12 KIY46316.1 - 0.68 10.6 13.9 5.9 7.6 1.5 4.6 4 1 1 5 5 5 0 SlyX NYD-SP28_assoc PF14775.6 KIY46316.1 - 0.93 9.6 10.0 0.29 11.3 1.8 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain YabA PF06156.13 KIY46316.1 - 1.6 9.4 13.5 3.5 8.3 3.7 3.3 2 2 1 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 KIY46316.1 - 8.6 6.9 15.2 0.23 11.9 2.0 3.4 4 0 0 4 4 4 0 Cell division protein ZapB Barwin PF00967.17 KIY46317.1 - 0.00026 20.8 0.2 0.00042 20.1 0.2 1.3 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 KIY46317.1 - 0.00029 21.0 0.9 0.00047 20.4 0.9 1.5 1 1 0 1 1 1 1 Lytic transglycolase Methyltransf_23 PF13489.6 KIY46318.1 - 3.8e-11 43.1 0.0 6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY46318.1 - 2.2e-09 37.3 0.0 4.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY46318.1 - 5.2e-09 36.7 0.0 1.6e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY46318.1 - 2.4e-07 31.4 0.0 5.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY46318.1 - 2.3e-06 28.2 0.0 5.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIY46318.1 - 1.2e-05 24.9 0.0 8.4e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KIY46318.1 - 0.00066 19.8 0.0 0.0017 18.5 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase PrmA PF06325.13 KIY46318.1 - 0.00087 18.8 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIY46318.1 - 0.0044 16.6 0.0 0.014 14.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KIY46318.1 - 0.0051 16.1 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KIY46318.1 - 0.038 13.3 0.0 0.13 11.6 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family polyprenyl_synt PF00348.17 KIY46319.1 - 3e-22 78.9 0.0 1.3e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase DUF4843 PF16132.5 KIY46321.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4843) zf-C2H2 PF00096.26 KIY46322.1 - 0.00095 19.5 14.3 0.11 12.9 1.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type RRM_1 PF00076.22 KIY46323.1 - 9.5e-15 54.2 0.1 3.7e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIY46323.1 - 0.023 14.7 0.1 4.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KIY46323.1 - 0.12 12.0 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 KIY46324.1 - 1.6e-59 200.1 0.0 1.8e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY46324.1 - 3.6e-36 124.0 0.0 5.1e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY46324.1 - 4.2e-13 49.1 0.0 4.9e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIY46324.1 - 7.6e-06 25.9 0.4 0.043 13.7 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIY46324.1 - 9.4e-06 25.7 0.0 1.5e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY46324.1 - 2e-05 24.2 0.0 4.8e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIY46324.1 - 3.9e-05 23.1 0.0 4.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KIY46324.1 - 0.01 16.2 0.1 0.022 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF89 PF01937.19 KIY46324.1 - 0.061 12.3 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 TniB PF05621.11 KIY46324.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 KIY46324.1 - 0.13 11.7 0.1 0.38 10.2 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DoxA PF07680.11 KIY46324.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 TQO small subunit DoxA HET PF06985.11 KIY46325.1 - 0.011 16.1 0.3 0.022 15.1 0.3 1.7 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DOCK-C2 PF14429.6 KIY46325.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins RasGEF PF00617.19 KIY46326.1 - 7.2e-45 153.3 0.0 1.3e-44 152.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY46326.1 - 6.3e-17 61.7 0.2 1.2e-16 60.8 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KIY46326.1 - 3.5e-13 48.9 0.2 6.9e-13 48.0 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIY46326.1 - 5.5e-08 32.4 0.0 5.7e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KIY46326.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ist1 PF03398.14 KIY46327.1 - 1.1e-57 194.5 2.5 1.2e-57 194.4 2.5 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DPBB_1 PF03330.18 KIY46328.1 - 3.3e-05 24.1 0.1 7.5e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase PRK PF00485.18 KIY46329.1 - 0.033 13.9 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KIY46329.1 - 0.19 11.9 0.2 1.2 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMM1 PF10296.9 KIY46331.1 - 6.5e-07 28.7 0.0 2.3e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 KIY46331.1 - 0.1 13.1 0.0 0.48 11.0 0.0 2.1 1 1 0 1 1 1 0 PH domain ATG16 PF08614.11 KIY46333.1 - 0.002 18.4 41.2 0.012 15.8 2.6 3.9 1 1 2 4 4 4 2 Autophagy protein 16 (ATG16) TACC_C PF05010.14 KIY46333.1 - 0.003 17.4 18.1 0.0077 16.0 14.4 3.1 2 1 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal OmpH PF03938.14 KIY46333.1 - 0.012 15.9 20.7 0.065 13.6 4.9 3.2 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Lebercilin PF15619.6 KIY46333.1 - 0.019 14.6 26.2 0.88 9.2 0.3 3.9 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Uso1_p115_C PF04871.13 KIY46333.1 - 0.026 14.9 31.3 0.027 14.8 8.7 3.5 2 2 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 KIY46333.1 - 0.031 13.1 29.7 0.91 8.3 14.2 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein FBPase PF00316.20 KIY46333.1 - 0.057 12.9 1.0 0.11 11.9 1.0 1.5 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain DUF3256 PF11644.8 KIY46333.1 - 0.067 12.7 0.5 0.13 11.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Spc29 PF17082.5 KIY46333.1 - 0.077 12.8 11.2 1 9.2 1.8 3.0 1 1 1 2 2 2 0 Spindle Pole Component 29 GldM_N PF12081.8 KIY46333.1 - 0.13 12.4 8.7 0.22 11.6 4.6 2.9 2 1 1 3 3 3 0 GldM N-terminal domain KASH_CCD PF14662.6 KIY46333.1 - 0.18 11.6 24.0 0.27 11.1 6.8 3.5 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH VPS38 PF17649.1 KIY46333.1 - 0.21 10.4 9.5 0.018 13.9 2.3 2.4 2 1 1 3 3 3 0 Vacuolar protein sorting 38 CCDC144C PF14915.6 KIY46333.1 - 0.22 10.6 27.4 0.036 13.2 12.9 2.8 1 1 1 3 3 3 0 CCDC144C protein coiled-coil region Golgin_A5 PF09787.9 KIY46333.1 - 0.24 10.9 27.8 1.4 8.3 0.6 2.8 1 1 0 2 2 2 0 Golgin subfamily A member 5 Bacillus_HBL PF05791.11 KIY46333.1 - 0.25 11.2 11.8 0.15 11.9 0.9 3.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 KIY46333.1 - 0.3 11.1 30.1 0.54 10.3 0.8 4.0 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 KIY46333.1 - 0.35 10.7 18.3 3.2 7.5 3.2 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 KIY46333.1 - 0.36 9.4 16.4 1.1 7.9 5.7 2.2 1 1 1 2 2 2 0 AAA domain Fez1 PF06818.15 KIY46333.1 - 0.46 10.9 28.9 0.075 13.5 15.1 3.0 1 1 1 2 2 2 0 Fez1 HIP1_clath_bdg PF16515.5 KIY46333.1 - 0.62 10.7 32.0 0.37 11.4 2.6 4.5 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KIY46333.1 - 1.2 9.2 12.7 7.4 6.6 0.4 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) ZapB PF06005.12 KIY46333.1 - 1.3 9.5 30.4 15 6.1 6.5 5.4 3 1 1 4 4 2 0 Cell division protein ZapB Lectin_N PF03954.14 KIY46333.1 - 1.9 8.2 17.3 1.6 8.5 1.3 3.7 3 1 1 4 4 4 0 Hepatic lectin, N-terminal domain FliD_N PF02465.18 KIY46333.1 - 2.2 9.0 13.3 1.8 9.3 6.2 3.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.10 KIY46333.1 - 3.1 8.0 15.1 15 5.7 0.1 3.4 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KIY46333.1 - 3.2 7.8 26.6 1 9.4 10.5 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 KIY46333.1 - 3.3 7.6 18.2 1.1 9.2 3.4 3.6 2 1 2 4 4 4 0 Axonemal dynein light chain FapA PF03961.13 KIY46333.1 - 4.5 5.8 14.8 0.83 8.2 1.8 2.9 1 1 1 3 3 3 0 Flagellar Assembly Protein A DUF4472 PF14739.6 KIY46333.1 - 4.5 8.0 23.2 0.99 10.2 0.1 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4472) YabA PF06156.13 KIY46333.1 - 4.7 7.9 19.2 17 6.1 4.3 4.2 2 1 3 5 5 5 0 Initiation control protein YabA Alpha-2-MRAP_C PF06401.11 KIY46333.1 - 4.8 7.1 13.5 4.8 7.1 10.1 2.6 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF4140 PF13600.6 KIY46333.1 - 4.9 7.7 23.8 10 6.6 0.6 4.6 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 KIY46333.1 - 4.9 6.1 29.0 5.1 6.1 4.2 3.1 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 KIY46333.1 - 5 7.4 29.4 9.4 6.5 1.2 5.2 2 1 3 5 5 5 0 Spc24 subunit of Ndc80 DUF4795 PF16043.5 KIY46333.1 - 5.4 6.6 20.0 5.2 6.6 15.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) THOC7 PF05615.13 KIY46333.1 - 5.5 7.3 29.1 2.7 8.3 9.4 3.6 2 1 1 3 3 3 0 Tho complex subunit 7 DUF4407 PF14362.6 KIY46333.1 - 5.9 6.2 24.8 3.8 6.8 8.9 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KIY46333.1 - 7.6 7.0 16.8 21 5.6 0.6 5.6 6 0 0 6 6 5 0 Flagella accessory protein C (FlaC) zf-CpG_bind_C PF12269.8 KIY46333.1 - 8.3 6.1 10.3 4.8 6.9 0.8 3.0 2 1 2 4 4 4 0 CpG binding protein zinc finger C terminal domain DUF3450 PF11932.8 KIY46333.1 - 9.2 5.5 25.7 0.45 9.8 7.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Cep57_CLD_2 PF14197.6 KIY46333.1 - 9.5 6.4 33.7 1.3 9.2 6.8 5.3 3 2 2 5 5 5 0 Centrosome localisation domain of PPC89 WD40 PF00400.32 KIY46334.1 - 2.9e-41 138.7 20.8 3e-07 31.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY46334.1 - 4e-16 59.1 0.0 0.0044 17.3 0.1 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY46334.1 - 0.00098 19.0 0.0 1.5 8.7 0.0 2.7 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIY46334.1 - 0.0012 18.2 0.0 0.33 10.2 0.0 3.3 2 1 1 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 KIY46334.1 - 0.12 10.9 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain MRP-L28 PF09812.9 KIY46335.1 - 2.1e-08 34.5 6.9 1.7e-07 31.5 3.3 2.5 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L28 Golgin_A5 PF09787.9 KIY46335.1 - 0.0064 16.0 2.2 0.0085 15.6 2.2 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 ARA70 PF12489.8 KIY46335.1 - 0.045 13.9 0.9 0.067 13.4 0.9 1.2 1 0 0 1 1 1 0 Nuclear coactivator PCI PF01399.27 KIY46336.1 - 1.3e-18 67.4 0.7 5.8e-18 65.3 0.3 2.3 1 1 1 2 2 2 1 PCI domain DUF5517 PF17639.2 KIY46336.1 - 0.0024 18.2 4.1 0.079 13.3 0.1 3.2 3 0 0 3 3 3 2 Family of unknown function (DUF5517) dsrm PF00035.26 KIY46337.1 - 2.1e-07 31.5 0.0 2.7e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 KIY46338.1 - 1e-10 42.2 0.0 1.3e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribosomal_L1 PF00687.21 KIY46339.1 - 8.5e-16 58.3 0.0 1.1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family CODH_A_N PF18537.1 KIY46339.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Rsm22 PF09243.10 KIY46340.1 - 4.3e-41 141.0 0.0 4e-37 128.0 0.0 3.2 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 UCH PF00443.29 KIY46341.1 - 1.3e-28 100.2 0.0 1.8e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIY46341.1 - 2.5e-11 43.7 0.1 4.9e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KIY46341.1 - 0.0048 16.5 0.1 0.13 11.8 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase dsrm PF00035.26 KIY46343.1 - 0.00078 20.1 0.0 0.0012 19.5 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif PIP5K PF01504.18 KIY46344.1 - 1.9e-40 138.8 11.7 2.4e-34 118.8 0.3 2.6 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KIY46344.1 - 1.8e-26 92.9 0.0 2.7e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KIY46344.1 - 3.8e-16 59.0 14.1 3.8e-16 59.0 14.1 2.1 3 0 0 3 3 3 1 FYVE zinc finger Ribosomal_S27e PF01667.17 KIY46344.1 - 0.44 10.3 2.2 1.1 9.0 2.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 IBR PF01485.21 KIY46344.1 - 0.91 9.8 12.6 0.12 12.6 7.6 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 KIY46344.1 - 2 8.7 11.8 0.26 11.5 6.1 2.4 3 0 0 3 3 3 0 FYVE-type zinc finger LTV PF04180.14 KIY46345.1 - 8.6e-99 331.8 9.8 1.6e-94 317.8 4.8 2.2 1 1 1 2 2 2 2 Low temperature viability protein AcetylCoA_hydro PF02550.15 KIY46347.1 - 2.2e-45 155.1 0.0 3.6e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KIY46347.1 - 1.7e-40 138.5 0.0 2.6e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.12 KIY46347.1 - 0.054 12.4 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Peptidase_C48 PF02902.19 KIY46349.1 - 1.6e-07 31.4 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain gag_pre-integrs PF13976.6 KIY46350.1 - 1.5e-05 24.8 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Astro_capsid_p PF12226.8 KIY46351.1 - 3.3 6.8 13.1 6.1 5.9 13.1 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein MMR_HSR1_Xtn PF16897.5 KIY46352.1 - 3.8e-23 81.5 0.4 8.1e-23 80.5 0.3 1.6 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KIY46352.1 - 4.8e-05 23.3 0.0 8.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain Zn_clus PF00172.18 KIY46353.1 - 0.51 10.5 6.3 0.45 10.7 1.3 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KIY46355.1 - 6.4e-34 117.2 0.3 1.9e-16 60.3 0.5 2.1 1 1 1 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KIY46355.1 - 0.00089 19.3 0.0 0.0021 18.1 0.0 1.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIY46355.1 - 0.0027 17.5 0.0 0.0036 17.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY46355.1 - 0.036 14.4 0.1 0.12 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KIY46355.1 - 0.056 12.8 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 KIY46355.1 - 0.069 13.5 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-RING_11 PF17123.5 KIY46355.1 - 0.15 11.8 0.8 0.3 10.9 0.8 1.5 1 0 0 1 1 1 0 RING-like zinc finger Melibiase_2 PF16499.5 KIY46355.1 - 0.21 10.7 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Alpha galactosidase A Pkinase PF00069.25 KIY46356.1 - 2.6e-24 86.0 0.1 2.8e-24 85.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46356.1 - 9.6e-12 44.7 0.0 1e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY46356.1 - 3.5e-07 29.3 0.0 3.8e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY46356.1 - 2.7e-06 26.9 0.0 2.8e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY46356.1 - 0.00014 21.8 0.4 0.00019 21.5 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY46356.1 - 0.0038 16.2 0.3 0.0045 16.0 0.3 1.0 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KIY46356.1 - 0.0099 15.5 0.3 0.013 15.1 0.3 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KIY46356.1 - 0.01 15.2 0.3 0.012 15.0 0.3 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY46356.1 - 0.087 12.4 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KIY46356.1 - 0.11 11.6 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF765 PF05570.11 KIY46358.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) gag_pre-integrs PF13976.6 KIY46359.1 - 1.7e-05 24.6 0.1 2.2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain FeoA PF04023.14 KIY46359.1 - 0.095 13.0 0.1 0.31 11.3 0.1 1.8 2 0 0 2 2 2 0 FeoA domain CAP PF00188.26 KIY46361.1 - 0.073 13.9 0.7 1.4 9.7 0.0 2.1 2 0 0 2 2 2 0 Cysteine-rich secretory protein family zf-C3HC4_4 PF15227.6 KIY46364.1 - 6.6e-10 39.0 11.4 1.4e-09 37.9 11.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIY46364.1 - 7.1e-09 35.5 9.3 1.6e-08 34.4 9.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY46364.1 - 1.3e-08 35.0 11.8 3.5e-08 33.6 11.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY46364.1 - 2.3e-08 33.7 11.8 4.8e-08 32.7 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY46364.1 - 3.2e-07 30.1 12.5 8.2e-07 28.8 12.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY46364.1 - 1.5e-06 27.9 8.4 2.9e-06 27.0 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY46364.1 - 0.0014 18.5 10.7 0.0037 17.2 10.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KIY46364.1 - 0.0037 17.1 4.8 0.0095 15.8 4.8 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIY46364.1 - 0.011 16.0 7.5 0.011 16.0 7.5 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIY46364.1 - 0.024 14.7 2.7 0.058 13.4 2.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KIY46364.1 - 0.027 14.3 9.3 0.061 13.2 9.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KIY46364.1 - 0.049 13.5 5.0 0.12 12.2 5.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit MAM33 PF02330.16 KIY46364.1 - 0.06 13.3 0.2 0.099 12.6 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein zf-RING_10 PF16685.5 KIY46364.1 - 0.085 13.0 6.0 0.16 12.1 6.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KIY46364.1 - 0.15 11.9 4.2 0.43 10.4 4.2 1.9 1 0 0 1 1 1 0 RING-like zinc finger CENP-B_dimeris PF09026.10 KIY46364.1 - 0.53 10.7 7.8 0.46 10.9 5.3 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-RING_4 PF14570.6 KIY46364.1 - 7.9 6.4 8.1 19 5.1 8.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2704 PF10866.8 KIY46366.1 - 0.019 14.8 0.3 0.03 14.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) SporV_AA PF12164.8 KIY46366.1 - 1.2 9.6 4.5 17 5.9 0.1 3.0 3 0 0 3 3 3 0 Stage V sporulation protein AA OB_aCoA_assoc PF01796.17 KIY46370.1 - 0.052 13.6 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated Tetraspanin PF00335.20 KIY46370.1 - 0.071 12.8 11.2 0.12 12.1 11.4 1.4 1 1 0 1 1 1 0 Tetraspanin family O-antigen_lig PF13425.6 KIY46370.1 - 0.082 11.7 4.1 0.041 12.7 0.7 1.8 1 1 1 2 2 2 0 O-antigen ligase like membrane protein Vma12 PF11712.8 KIY46370.1 - 0.25 11.4 2.2 0.36 10.9 1.2 1.8 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PSI_PsaJ PF01701.18 KIY46370.1 - 1 9.9 7.7 0.56 10.8 3.1 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ DJ-1_PfpI PF01965.24 KIY46372.1 - 1.4e-36 125.8 0.0 1.7e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIY46372.1 - 0.0084 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 KIY46372.1 - 0.027 14.1 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Spt5-NGN PF03439.13 KIY46373.1 - 7.9e-21 73.8 0.0 1.8e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KIY46373.1 - 3.7e-19 68.0 19.1 8.4e-06 25.6 0.2 6.9 6 0 0 6 6 6 4 KOW motif CTD PF12815.7 KIY46373.1 - 4.6e-14 52.7 50.5 7e-10 39.3 17.4 3.1 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 KIY46373.1 - 4.5e-10 40.4 11.9 4.5e-10 40.4 11.9 3.0 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal TFIIF_alpha PF05793.12 KIY46373.1 - 0.0046 15.6 13.9 0.0071 15.0 13.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) S1_2 PF13509.6 KIY46373.1 - 0.027 14.5 0.5 3.4 7.8 0.1 3.6 3 0 0 3 3 3 0 S1 domain Drc1-Sld2 PF11719.8 KIY46373.1 - 1.1 8.8 14.5 1.9 7.9 14.5 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 KIY46373.1 - 2.2 6.4 14.6 2.8 6.0 14.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 KIY46373.1 - 4.7 6.3 18.1 7.6 5.6 18.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glyco_hydro_127 PF07944.12 KIY46374.1 - 9.7e-19 67.2 0.0 4.4e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Exo_endo_phos PF03372.23 KIY46375.1 - 5.8e-09 35.8 0.0 5.9e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 KIY46375.1 - 2.9e-05 24.0 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain APH PF01636.23 KIY46376.1 - 4.2e-17 62.9 0.4 1.9e-16 60.7 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KIY46376.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 KIY46376.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) CHCH PF06747.13 KIY46377.1 - 5.3e-06 26.4 2.7 9.2e-06 25.7 2.7 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KIY46377.1 - 0.023 15.0 3.5 0.046 14.0 3.5 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KIY46377.1 - 0.032 14.2 1.1 0.13 12.3 1.2 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KIY46377.1 - 0.1 12.6 2.6 0.16 12.0 2.6 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MFS_1 PF07690.16 KIY46378.1 - 7.1e-15 54.8 24.8 8.1e-15 54.6 24.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_3 PF13302.7 KIY46379.1 - 8.6e-16 58.9 0.0 1.7e-15 57.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY46379.1 - 8.1e-11 42.2 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY46379.1 - 3.9e-07 30.4 0.0 5.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY46379.1 - 6.2e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIY46379.1 - 0.00035 20.5 0.0 0.00045 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIY46379.1 - 0.0023 17.6 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PI31_Prot_N PF11566.8 KIY46379.1 - 0.2 11.4 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal WD40 PF00400.32 KIY46380.1 - 5.4e-22 77.7 4.0 8.4e-05 23.3 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY46380.1 - 4.2e-11 43.0 0.0 2.2e-05 24.7 0.0 4.8 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY46380.1 - 0.00052 20.0 0.0 0.069 13.0 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIY46380.1 - 0.2 10.6 0.2 3.4 6.6 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MYT1 PF08474.11 KIY46380.1 - 0.33 10.9 3.6 5 7.0 0.0 2.3 2 0 0 2 2 2 0 Myelin transcription factor 1 Ribosomal_L27e PF01777.18 KIY46381.1 - 5.1e-36 122.9 3.9 6.8e-36 122.5 3.9 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KIY46381.1 - 0.0034 17.3 0.2 0.009 15.9 0.2 1.7 1 0 0 1 1 1 1 KOW motif Nro1 PF12753.7 KIY46382.1 - 0.0022 17.1 0.2 0.16 10.9 0.0 2.4 3 0 0 3 3 3 2 Nuclear pore complex subunit Nro1 TPR_12 PF13424.6 KIY46382.1 - 0.14 12.4 2.5 0.81 10.0 0.4 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat NCD1 PF04904.13 KIY46382.1 - 0.2 11.7 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) TPR_7 PF13176.6 KIY46382.1 - 0.99 9.6 3.0 5.3 7.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BAG PF02179.16 KIY46383.1 - 5.2e-06 26.8 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 BAG domain Cytochrom_D1 PF02239.16 KIY46383.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF4692 PF15763.5 KIY46384.1 - 0.17 12.3 0.3 0.54 10.7 0.0 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) SET PF00856.28 KIY46385.1 - 1.4e-06 28.8 0.0 3.2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 SET domain GATA PF00320.27 KIY46386.1 - 8e-25 86.2 22.1 4.8e-13 48.5 5.7 2.1 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KIY46386.1 - 0.0059 16.1 5.0 0.83 9.2 1.5 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Vps36-NZF-N PF16988.5 KIY46386.1 - 0.1 12.0 8.5 0.38 10.2 0.3 3.0 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain eIF-5_eIF-2B PF01873.17 KIY46386.1 - 0.5 10.2 9.0 4.4 7.2 0.4 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.10 KIY46386.1 - 0.66 10.1 10.2 3.5 7.8 0.3 2.9 2 1 1 3 3 3 0 Zinc ribbon domain NMD3 PF04981.13 KIY46386.1 - 1.1 8.7 7.3 2.7 7.4 0.2 2.1 1 1 1 2 2 2 0 NMD3 family DZR PF12773.7 KIY46386.1 - 1.1 9.3 14.0 3.8e+02 1.2 14.0 3.0 1 1 0 1 1 1 0 Double zinc ribbon CTU2 PF10288.9 KIY46386.1 - 6.6 7.0 8.4 0.5 10.6 3.6 1.6 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Nup54 PF13874.6 KIY46387.1 - 6e-34 117.1 2.3 1.1e-33 116.2 2.3 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KIY46387.1 - 1.2e-20 74.1 92.8 4.1e-11 43.6 34.7 4.1 2 1 1 3 3 3 2 Nucleoporin FG repeat region SUIM_assoc PF16619.5 KIY46387.1 - 1.1 9.3 12.6 0.56 10.3 2.4 3.6 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Fungal_trans PF04082.18 KIY46388.1 - 2.5e-14 52.9 0.1 3.7e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY46388.1 - 6.5e-07 29.4 8.6 1.4e-06 28.3 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.12 KIY46388.1 - 0.026 14.5 0.1 0.098 12.7 0.1 1.9 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 OrfB_Zn_ribbon PF07282.11 KIY46388.1 - 0.87 9.6 3.3 1.9 8.5 3.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain p450 PF00067.22 KIY46390.1 - 2e-68 231.2 0.2 5.5e-67 226.5 0.1 2.3 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 KIY46391.1 - 1.2e-52 179.3 0.0 2.2e-52 178.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KIY46392.1 - 4e-12 46.2 0.0 7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY46392.1 - 4.9e-08 33.1 0.0 7.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY46392.1 - 0.0068 15.9 0.0 0.016 14.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIY46392.1 - 0.027 13.6 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KIY46392.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase BTB PF00651.31 KIY46393.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-RVT PF13966.6 KIY46394.1 - 6.6e-06 26.8 0.1 9.7e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Imm27 PF15590.6 KIY46395.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 27 BTB PF00651.31 KIY46397.1 - 0.0063 16.7 0.1 0.007 16.6 0.1 1.1 1 0 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.18 KIY46399.1 - 0.0067 16.5 6.1 0.011 15.8 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY46399.1 - 0.11 11.4 0.0 0.28 10.2 0.0 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain Paralemmin PF03285.15 KIY46399.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Paralemmin Pheromone PF08015.11 KIY46401.1 - 0.00013 23.0 4.7 0.14 13.3 1.7 2.7 2 1 0 2 2 2 2 Fungal mating-type pheromone Mfa1 PF17445.2 KIY46401.1 - 1.1 9.3 5.9 2.5 8.2 0.5 2.2 2 0 0 2 2 2 0 Mating factor A1 Peptidase_A4 PF01828.17 KIY46402.1 - 3.7e-80 268.3 18.8 4.5e-80 268.0 18.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF585 PF04522.12 KIY46402.1 - 0.0012 18.5 0.7 0.0016 18.1 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF585) dbPDZ_assoc PF16610.5 KIY46402.1 - 0.18 12.1 5.0 2.1 8.6 1.0 2.5 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 GMC_oxred_N PF00732.19 KIY46404.1 - 2.8e-56 191.1 0.0 3.6e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY46404.1 - 5.1e-34 117.9 0.0 9.2e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_oxidored PF12831.7 KIY46405.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Bowman-Birk_leg PF00228.20 KIY46405.1 - 0.031 14.7 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family TFIIS_C PF01096.18 KIY46406.1 - 2.4e-14 52.9 4.2 2.4e-14 52.9 4.2 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIY46406.1 - 0.00013 21.8 3.8 0.23 11.4 0.3 2.9 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DUF523 PF04463.12 KIY46406.1 - 0.00096 19.2 0.1 0.0011 19.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) zf-ribbon_3 PF13248.6 KIY46406.1 - 0.0022 17.4 6.7 0.61 9.6 0.1 3.1 3 0 0 3 3 3 2 zinc-ribbon domain zf-RING_7 PF02591.15 KIY46406.1 - 0.0025 18.0 1.0 2 8.7 0.0 3.3 3 0 0 3 3 3 1 C4-type zinc ribbon domain CpXC PF14353.6 KIY46406.1 - 0.007 16.4 3.8 0.07 13.2 2.2 2.4 2 1 0 2 2 2 1 CpXC protein Zn_Tnp_IS1595 PF12760.7 KIY46406.1 - 0.0087 16.0 4.1 0.11 12.5 2.1 2.4 2 1 0 2 2 2 1 Transposase zinc-ribbon domain DUF3268 PF11672.8 KIY46406.1 - 0.034 14.5 2.2 0.077 13.3 1.6 1.9 2 0 0 2 2 2 0 zinc-finger-containing domain Baculo_LEF5_C PF11792.8 KIY46406.1 - 0.043 13.5 0.7 0.043 13.5 0.7 1.9 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DUF2752 PF10825.8 KIY46406.1 - 0.067 13.3 1.1 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zinc_ribbon_10 PF10058.9 KIY46406.1 - 0.078 12.7 2.2 8.4 6.2 0.0 3.1 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Nudix_N_2 PF14803.6 KIY46406.1 - 0.12 12.3 4.8 6.8 6.7 0.0 3.0 2 1 0 2 2 2 0 Nudix N-terminal Methyltransf_13 PF08421.11 KIY46406.1 - 0.13 12.5 4.7 1 9.7 0.1 2.7 3 0 0 3 3 3 0 Putative zinc binding domain Terminase_GpA PF05876.12 KIY46406.1 - 0.14 10.6 3.9 0.039 12.5 1.4 1.3 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Zn-ribbon_8 PF09723.10 KIY46406.1 - 0.15 12.2 5.9 3.8 7.7 0.0 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KIY46406.1 - 0.16 11.7 7.9 1.9 8.3 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF35_N PF12172.8 KIY46406.1 - 0.17 11.8 6.1 0.86 9.5 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TF_Zn_Ribbon PF08271.12 KIY46406.1 - 0.22 11.1 7.2 5.8 6.5 3.4 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 KIY46406.1 - 0.26 11.3 9.4 34 4.6 9.4 2.6 1 1 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.16 KIY46406.1 - 0.3 11.1 4.1 12 6.0 0.9 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain UPF0547 PF10571.9 KIY46406.1 - 0.36 11.0 0.4 0.36 11.0 0.4 2.7 3 0 0 3 3 2 0 Uncharacterised protein family UPF0547 zf-C4_Topoisom PF01396.19 KIY46406.1 - 0.54 10.1 10.8 2.6 7.9 5.1 3.1 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf_UBZ PF18439.1 KIY46406.1 - 0.73 9.5 5.0 14 5.3 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 KIY46406.1 - 1.5 8.9 5.2 1.5 8.9 3.2 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Auto_anti-p27 PF06677.12 KIY46406.1 - 1.8 8.8 6.7 41 4.4 3.3 3.1 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ACC PF17848.1 KIY46406.1 - 2.4 8.3 10.5 4.2 7.5 1.0 3.2 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DNA_RNApol_7kD PF03604.13 KIY46406.1 - 3.1 7.6 8.3 16 5.2 0.2 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_3 PF13878.6 KIY46406.1 - 3.1 7.7 8.0 12 5.8 0.0 3.3 3 1 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO Rubredoxin_2 PF18073.1 KIY46406.1 - 5.2 6.9 8.7 3 7.7 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-TFIIB PF13453.6 KIY46406.1 - 7 6.1 7.7 8.6 5.8 0.3 3.1 2 2 1 3 3 3 0 Transcription factor zinc-finger Ogr_Delta PF04606.12 KIY46406.1 - 8.5 6.4 10.1 0.79 9.8 3.5 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Pkinase PF00069.25 KIY46408.1 - 2.3e-32 112.4 0.0 2.6e-30 105.7 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46408.1 - 9.7e-14 51.3 0.0 7.9e-06 25.3 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KIY46410.1 - 8.1e-20 71.8 0.0 1.1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY46410.1 - 2.5e-05 24.0 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KIY46410.1 - 0.06 12.7 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY46410.1 - 0.081 12.5 0.0 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 RIO1 family SesA PF17107.5 KIY46411.1 - 0.007 16.5 0.0 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-C4pol PF14260.6 KIY46411.1 - 0.13 12.7 0.1 0.35 11.4 0.1 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta GATA PF00320.27 KIY46412.1 - 2.7e-17 62.1 3.9 3.5e-17 61.7 3.9 1.2 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 KIY46412.1 - 0.0028 17.1 2.0 0.0031 17.0 1.1 1.5 2 0 0 2 2 2 1 TFIIB zinc-binding ArfGap PF01412.18 KIY46412.1 - 0.024 14.7 0.3 0.027 14.5 0.3 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DUF4092 PF13322.6 KIY46413.1 - 0.15 11.9 0.1 6.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4092) YorP PF09629.10 KIY46414.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 YorP protein Zn_clus PF00172.18 KIY46415.1 - 0.0057 16.8 4.2 0.0094 16.1 4.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lyase_catalyt PF09093.11 KIY46421.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Lyase, catalytic Collagen PF01391.18 KIY46422.1 - 0.041 13.7 7.2 0.059 13.1 7.2 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Plavaka PF18759.1 KIY46423.1 - 1.7e-19 70.2 0.1 5.6e-16 58.7 0.1 2.1 1 1 1 2 2 2 2 Plavaka transposase SR-25 PF10500.9 KIY46425.1 - 0.086 12.4 7.3 0.15 11.6 7.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3350 PF11830.8 KIY46425.1 - 0.098 13.0 1.3 0.22 11.9 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) Sugar_tr PF00083.24 KIY46426.1 - 1.2e-09 37.6 0.5 1.3e-09 37.5 0.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PIG-S PF10510.9 KIY46428.1 - 8.5e-07 28.2 0.0 8.7e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Amidohydro_1 PF01979.20 KIY46429.1 - 5.5e-08 32.5 0.0 8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Cytochrom_C PF00034.21 KIY46432.1 - 3.3e-11 44.2 0.0 5.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KIY46432.1 - 4.7e-08 33.2 2.6 4e-07 30.3 2.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KIY46432.1 - 0.0013 18.4 0.9 0.0057 16.4 0.9 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 KIY46432.1 - 0.056 14.1 0.0 0.06 14.0 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.9 KIY46432.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 HAUS6_N PF14661.6 KIY46433.1 - 3.8e-05 23.4 0.1 0.00026 20.7 0.1 1.9 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Epimerase PF01370.21 KIY46433.1 - 0.081 12.4 0.0 0.095 12.1 0.0 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SPT2 PF08243.11 KIY46434.1 - 2.3 8.8 10.5 3.1 8.4 10.5 1.1 1 0 0 1 1 1 0 SPT2 chromatin protein Plavaka PF18759.1 KIY46435.1 - 1.5e-104 349.8 0.0 2.8e-104 348.8 0.0 1.5 1 1 0 1 1 1 1 Plavaka transposase DUF1861 PF08950.10 KIY46435.1 - 0.084 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1861) zf-C2H2 PF00096.26 KIY46436.1 - 0.066 13.7 0.1 0.19 12.2 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Protoglobin PF11563.8 KIY46437.1 - 8.3e-08 32.3 0.0 1e-07 32.0 0.0 1.0 1 0 0 1 1 1 1 Protoglobin ELFV_dehydrog PF00208.21 KIY46438.1 - 2.4e-15 56.9 0.0 3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KIY46438.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain HAMP PF00672.25 KIY46438.1 - 0.13 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 HAMP domain Phage_integrase PF00589.22 KIY46440.1 - 0.0078 16.0 0.0 0.018 14.8 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family LSM14 PF12701.7 KIY46441.1 - 9.3e-22 76.9 0.0 1.7e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KIY46441.1 - 0.00033 21.5 5.3 0.00053 20.8 2.9 2.3 1 1 1 2 2 2 1 FDF domain SM-ATX PF14438.6 KIY46441.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.11 KIY46441.1 - 0.15 10.8 0.9 0.23 10.2 0.9 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Tyrosinase PF00264.20 KIY46442.1 - 4.1e-32 112.3 0.5 6.7e-32 111.6 0.5 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KIY46442.1 - 8e-09 36.2 0.0 1.7e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain RNA_polI_A34 PF08208.11 KIY46443.1 - 2.1e-26 93.3 2.0 2.1e-26 93.3 2.0 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF4614 PF15391.6 KIY46443.1 - 2.4 8.1 7.3 11 6.0 2.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) ASL_C PF08328.11 KIY46444.1 - 0.0017 18.5 0.2 0.0026 17.9 0.2 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal ApoLp-III PF07464.11 KIY46444.1 - 0.0086 16.2 2.1 0.88 9.7 0.6 2.4 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KIY46444.1 - 0.018 15.0 17.7 0.018 15.0 17.7 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 KIY46444.1 - 0.05 13.8 0.2 0.076 13.2 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding RPW8 PF05659.11 KIY46444.1 - 0.12 12.1 0.2 0.22 11.2 0.1 1.5 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CENP-F_leu_zip PF10473.9 KIY46444.1 - 0.14 12.1 0.2 0.23 11.5 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CHDCT2 PF08074.11 KIY46444.1 - 0.6 10.3 6.9 23 5.1 4.3 2.7 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Fib_alpha PF08702.10 KIY46444.1 - 0.72 10.0 3.6 1.4 9.1 3.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Muted PF14942.6 KIY46444.1 - 0.97 9.8 4.0 18 5.6 1.0 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DNA_PPF PF02916.15 KIY46444.1 - 0.98 9.8 10.8 0.7 10.3 7.0 2.1 1 1 1 2 2 2 0 DNA polymerase processivity factor DUF2178 PF09946.9 KIY46444.1 - 1.1 9.5 5.4 3.5 7.9 5.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2178) Methyltransf_2 PF00891.18 KIY46447.1 - 6.9e-20 71.2 0.0 8.8e-18 64.4 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_31 PF13847.6 KIY46447.1 - 0.008 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY46447.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY46447.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KIY46447.1 - 0.057 12.9 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 KIY46447.1 - 0.079 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIY46447.1 - 0.093 13.4 0.0 0.25 12.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 KIY46448.1 - 3.6e-42 144.0 0.1 4.8e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY46448.1 - 4.6e-34 118.0 0.1 6.6e-34 117.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY46448.1 - 6.4e-12 45.7 0.0 4.4e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY46448.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY46448.1 - 0.043 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KIY46448.1 - 0.15 12.0 0.1 1.3 8.9 0.0 2.3 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BBE PF08031.12 KIY46449.1 - 2.8e-11 43.4 0.7 6.7e-11 42.1 0.7 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KIY46449.1 - 5.7e-07 29.4 0.1 1e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Apolipoprotein PF01442.18 KIY46450.1 - 0.2 11.5 8.7 0.27 11.1 7.7 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ERp29 PF07749.12 KIY46450.1 - 1.5 9.8 6.9 0.43 11.5 1.2 2.8 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DIRP PF06584.13 KIY46450.1 - 3.8 7.7 6.8 42 4.4 2.3 3.0 2 1 0 2 2 2 0 DIRP Med3 PF11593.8 KIY46450.1 - 5.6 6.0 13.4 0.17 11.0 6.8 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal KDZ PF18758.1 KIY46451.1 - 7e-89 297.2 0.5 1e-88 296.7 0.5 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY46451.1 - 0.00017 21.7 0.0 0.00046 20.3 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Hist_deacetyl PF00850.19 KIY46452.1 - 4.3e-61 207.1 0.0 5.4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Tyr-DNA_phospho PF06087.12 KIY46453.1 - 1.3e-48 166.0 0.0 4.3e-45 154.4 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KIY46453.1 - 0.00012 21.7 2.4 0.00048 19.8 1.7 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif PLDc_2 PF13091.6 KIY46453.1 - 0.032 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 PLD-like domain DUF3808 PF10300.9 KIY46455.1 - 2.1e-79 267.5 0.0 3e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_14 PF13428.6 KIY46455.1 - 0.56 11.2 3.3 57 4.9 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3198 PF11433.8 KIY46457.1 - 0.072 13.0 0.2 0.072 13.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Lipase_3 PF01764.25 KIY46458.1 - 3.2e-19 69.2 0.0 4.5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY46458.1 - 0.055 14.1 1.2 0.1 13.2 1.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Fun_ATP-synt_8 PF05933.13 KIY46459.1 - 1.9 8.7 7.8 0.2 11.9 0.6 2.8 2 1 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) adh_short_C2 PF13561.6 KIY46460.1 - 1.1e-52 178.9 0.9 1.6e-52 178.4 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY46460.1 - 7.1e-50 169.2 2.2 8.9e-50 168.9 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY46460.1 - 7.7e-09 35.7 0.7 1.1e-08 35.2 0.7 1.3 1 0 0 1 1 1 1 KR domain Ank_2 PF12796.7 KIY46462.1 - 5.7e-17 62.1 0.0 9.9e-10 38.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY46462.1 - 1.2e-13 51.0 0.1 3.2e-07 30.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY46462.1 - 5.1e-11 42.5 0.2 0.014 15.8 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KIY46462.1 - 3.2e-10 39.3 0.0 0.016 15.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KIY46462.1 - 7.3e-10 39.2 0.0 0.00043 20.8 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF2773 PF10971.8 KIY46462.1 - 0.053 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Ank_2 PF12796.7 KIY46463.1 - 1.2e-12 48.2 0.1 5.3e-09 36.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY46463.1 - 7.7e-08 32.5 0.6 0.0064 16.8 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY46463.1 - 3.4e-07 30.4 3.7 0.0064 16.9 0.3 4.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KIY46463.1 - 1.4e-06 28.7 0.1 0.052 14.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY46463.1 - 0.00042 20.5 0.1 1 10.2 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat DUF4635 PF15466.6 KIY46463.1 - 0.0012 18.3 0.3 0.0026 17.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4635) UPF0449 PF15136.6 KIY46463.1 - 0.15 12.6 0.4 0.42 11.1 0.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Fungal_lectin PF07938.12 KIY46464.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal fucose-specific lectin HH_signal PF01085.18 KIY46464.1 - 0.12 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Fungal_trans PF04082.18 KIY46466.1 - 1.7e-19 69.9 0.4 2.9e-19 69.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 KIY46467.1 - 1.6e-14 55.1 0.9 3.1e-14 54.1 0.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY46467.1 - 4.2e-14 52.8 0.2 6.1e-14 52.3 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY46467.1 - 0.0021 17.4 0.0 0.0081 15.5 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIY46467.1 - 0.098 11.5 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme SHOCT PF09851.9 KIY46467.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Short C-terminal domain Chlorophyllase PF07224.11 KIY46467.1 - 0.19 10.7 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF89 PF01937.19 KIY46469.1 - 8.6e-108 360.4 0.0 9.8e-108 360.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 PCI PF01399.27 KIY46470.1 - 4.4e-14 52.9 0.0 9.7e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain F-box-like PF12937.7 KIY46471.1 - 1.1e-07 31.6 0.0 4.2e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY46471.1 - 0.0067 16.3 0.5 0.15 11.9 0.6 3.2 2 1 0 2 2 2 1 F-box domain zf-C3HC4_3 PF13920.6 KIY46472.1 - 9.8e-10 38.1 12.2 1.2e-09 37.9 1.2 2.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY46472.1 - 0.00025 20.9 0.3 0.00025 20.9 0.3 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY46472.1 - 0.00095 19.0 4.2 0.00095 19.0 4.2 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIY46472.1 - 0.0073 16.6 1.6 0.0073 16.6 1.6 2.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KIY46472.1 - 0.039 13.9 2.3 0.45 10.5 0.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain HicA_toxin PF07927.12 KIY46473.1 - 1.6e-07 31.3 0.1 4.2e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, TRP PF06011.12 KIY46476.1 - 2.1e-27 95.9 18.4 1.5e-26 93.1 18.4 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel MgtE PF01769.16 KIY46477.1 - 0.69 10.3 9.6 0.12 12.8 5.9 1.6 1 1 1 2 2 2 0 Divalent cation transporter Tad PF13400.6 KIY46477.1 - 4.8 7.6 9.1 0.77 10.1 0.2 2.6 2 1 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Oxidored_FMN PF00724.20 KIY46478.1 - 1e-12 48.1 0.0 1.1e-11 44.6 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family HNH_2 PF13391.6 KIY46479.1 - 0.0093 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease tRNA-synt_His PF13393.6 KIY46479.1 - 0.029 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase HNH_2 PF13391.6 KIY46481.1 - 0.0036 17.4 0.0 0.0088 16.2 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease 14-3-3 PF00244.20 KIY46485.1 - 5.6e-35 120.8 0.1 6.5e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 KIY46485.1 - 0.068 13.7 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Presenilin PF01080.17 KIY46486.1 - 0.1 11.3 0.6 0.12 11.1 0.6 1.0 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 KIY46486.1 - 6.8 6.0 17.9 8.8 5.6 17.9 1.1 1 0 0 1 1 1 0 SDA1 Halo_GVPC PF05465.13 KIY46489.1 - 0.047 14.0 2.9 38 4.7 0.0 4.7 6 0 0 6 6 6 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF3000 PF11452.8 KIY46489.1 - 0.11 12.1 0.4 20 4.6 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3000) RhoGEF PF00621.20 KIY46490.1 - 1.5e-40 139.4 0.7 2.6e-40 138.6 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KIY46490.1 - 1.2e-21 76.3 1.4 1e-09 38.1 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KIY46490.1 - 5.9e-18 64.2 4.0 4e-09 35.9 0.1 2.9 3 0 0 3 3 3 2 SH3 domain EF-hand_4 PF12763.7 KIY46490.1 - 3.5e-14 52.6 0.0 7.6e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand PH_13 PF16652.5 KIY46490.1 - 3.7e-13 49.6 1.0 5.5e-11 42.5 1.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 KIY46490.1 - 6.7e-11 41.7 0.6 0.00022 20.8 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain WH2 PF02205.20 KIY46490.1 - 2.3e-07 30.4 0.4 5e-07 29.4 0.4 1.5 1 0 0 1 1 1 1 WH2 motif PH PF00169.29 KIY46490.1 - 0.0024 18.4 0.0 0.0057 17.2 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 KIY46490.1 - 0.05 13.2 0.1 0.46 10.1 0.0 2.5 2 0 0 2 2 2 0 EF hand Rx_N PF18052.1 KIY46490.1 - 8.4 6.7 8.9 19 5.6 7.8 2.2 1 1 0 1 1 1 0 Rx N-terminal domain Sulfate_transp PF00916.20 KIY46492.1 - 5.8e-108 361.0 12.5 7.3e-108 360.7 12.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KIY46492.1 - 1.6e-08 34.2 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KIY46492.1 - 0.0006 20.1 0.1 0.0019 18.5 0.1 1.8 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KIY46492.1 - 0.0041 17.5 19.3 0.022 15.2 5.9 3.1 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily Metallophos PF00149.28 KIY46493.1 - 8.4e-38 130.9 0.2 1.3e-37 130.3 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY46493.1 - 0.00035 20.9 0.3 0.00069 20.0 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KIY46493.1 - 0.026 14.7 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 KIY46493.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Phage_T7_Capsid PF05396.11 KIY46494.1 - 0.0019 18.6 0.2 0.0037 17.6 0.2 1.4 1 0 0 1 1 1 1 Phage T7 capsid assembly protein THOC7 PF05615.13 KIY46494.1 - 0.018 15.3 0.2 0.027 14.8 0.2 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 HAUS6_N PF14661.6 KIY46494.1 - 0.036 13.7 0.2 0.052 13.1 0.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IFT57 PF10498.9 KIY46494.1 - 0.14 11.1 0.9 0.21 10.5 0.6 1.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Bap31_Bap29_C PF18035.1 KIY46494.1 - 0.17 11.9 0.2 6.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain LMP PF04778.12 KIY46494.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 LMP repeated region Tmpp129 PF10272.9 KIY46495.1 - 0.025 13.9 4.0 0.038 13.3 4.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor GerPB PF10803.8 KIY46495.1 - 0.2 11.7 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Spore germination GerPB TFB6 PF17110.5 KIY46496.1 - 4e-10 39.7 0.0 1.7e-09 37.6 0.0 1.8 1 1 1 2 2 2 1 Subunit 11 of the general transcription factor TFIIH Pacifastin_I PF05375.13 KIY46498.1 - 0.041 13.6 0.5 0.066 12.9 0.5 1.3 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) Pkinase PF00069.25 KIY46499.1 - 5.8e-12 45.5 0.0 1.7e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46499.1 - 8.1e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CE2_N PF17996.1 KIY46500.1 - 0.0043 17.0 0.1 0.071 13.1 0.1 2.0 1 1 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Ribosomal_L30_N PF08079.12 KIY46501.1 - 1.9e-28 98.5 15.7 1.9e-28 98.5 15.7 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KIY46501.1 - 1.1e-18 66.8 1.2 1.1e-18 66.8 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 KIY46501.1 - 0.083 12.7 0.9 0.85 9.4 0.1 2.2 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter Sugar_tr PF00083.24 KIY46502.1 - 3e-125 418.6 23.3 3.5e-125 418.4 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY46502.1 - 1.6e-16 60.2 49.2 3.9e-10 39.2 26.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Ceramidase PF05875.12 KIY46502.1 - 0.0091 15.5 0.7 0.0091 15.5 0.7 1.7 2 0 0 2 2 2 1 Ceramidase Pox_A14 PF05767.12 KIY46502.1 - 2.3 8.4 4.7 9.6 6.4 0.1 3.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Pkinase PF00069.25 KIY46503.1 - 7.1e-16 58.4 0.0 2.3e-14 53.4 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46503.1 - 2.9e-07 30.0 0.1 8.7e-07 28.5 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY46503.1 - 0.0053 15.6 0.0 0.0072 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Sulfate_transp PF00916.20 KIY46506.1 - 4.8e-15 55.2 0.9 5e-15 55.1 0.9 1.0 1 0 0 1 1 1 1 Sulfate permease family tRNA_bind PF01588.20 KIY46507.1 - 4.4e-28 97.2 0.0 8.2e-28 96.4 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KIY46507.1 - 2.5e-05 24.4 0.0 9.3e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY46507.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY46507.1 - 0.02 15.1 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KIY46507.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LYRIC PF15686.5 KIY46507.1 - 1.1 8.8 11.8 1.5 8.3 11.8 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Complex1_LYR PF05347.15 KIY46508.1 - 3.6e-09 36.5 0.3 4.9e-09 36.1 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIY46508.1 - 0.1 13.4 0.2 0.11 13.3 0.2 1.3 1 1 0 1 1 1 0 Complex1_LYR-like MRP-L47 PF06984.13 KIY46509.1 - 6.3e-22 77.5 0.1 6.3e-22 77.5 0.1 2.3 2 1 1 3 3 3 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 KIY46509.1 - 0.0012 18.8 0.1 0.0012 18.8 0.1 2.8 2 1 1 3 3 3 1 Ribosomal L29 protein 4PPT_N PF17837.1 KIY46509.1 - 0.23 11.6 5.6 1.6 8.9 4.9 2.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain DUF4518 PF15008.6 KIY46509.1 - 0.37 9.9 4.7 0.51 9.5 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) APG6_N PF17675.1 KIY46509.1 - 1.4 9.5 13.6 2.2 8.8 13.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 KIY46509.1 - 3.4 5.5 9.3 4.1 5.2 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SKA1 PF07160.12 KIY46509.1 - 4.7 7.0 17.8 4.1 7.2 5.8 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 PcfK PF14058.6 KIY46509.1 - 9.8 6.5 16.0 0.41 10.9 10.2 1.6 2 0 0 2 2 2 0 PcfK-like protein LSM PF01423.22 KIY46510.1 - 2.1e-18 65.8 0.4 2.4e-18 65.6 0.4 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY46510.1 - 2.7e-05 24.2 0.1 3.3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DER1 PF04511.15 KIY46511.1 - 1.8e-48 165.0 2.4 2.1e-48 164.8 2.4 1.0 1 0 0 1 1 1 1 Der1-like family DPBB_1 PF03330.18 KIY46512.1 - 5.3e-06 26.6 0.2 1.5e-05 25.2 0.2 1.9 1 1 0 1 1 1 1 Lytic transglycolase Zn_Tnp_IS1 PF03811.13 KIY46512.1 - 0.33 10.7 0.3 0.33 10.7 0.3 1.9 2 0 0 2 2 2 0 InsA N-terminal domain Ogr_Delta PF04606.12 KIY46512.1 - 0.42 10.6 4.6 3.7 7.6 0.1 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger F_bP_aldolase PF01116.20 KIY46513.1 - 2.8e-93 312.5 0.0 3.1e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Lipase_GDSL_2 PF13472.6 KIY46513.1 - 0.042 14.2 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AhpC-TSA PF00578.21 KIY46515.1 - 6.3e-21 74.6 0.0 9e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY46515.1 - 3.1e-11 43.2 0.0 4.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin zf-Tim10_DDP PF02953.15 KIY46516.1 - 1.5e-16 59.7 10.2 2e-16 59.4 10.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF5312 PF17239.2 KIY46516.1 - 0.016 13.6 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5312) DAHP_synth_1 PF00793.20 KIY46517.1 - 1e-96 323.0 0.0 1.3e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Peptidase_M75 PF09375.10 KIY46517.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Imelysin BTB PF00651.31 KIY46518.1 - 4.1e-05 23.8 0.0 8.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CBFD_NFYB_HMF PF00808.23 KIY46519.1 - 2e-07 31.2 0.0 3.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KIY46519.1 - 0.0082 16.2 0.1 0.017 15.2 0.1 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold adh_short_C2 PF13561.6 KIY46521.1 - 3.6e-54 183.8 0.3 4.1e-54 183.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY46521.1 - 3.4e-46 157.2 0.2 4.4e-46 156.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY46521.1 - 4.4e-15 56.1 0.7 6e-15 55.6 0.7 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY46521.1 - 0.0034 16.8 0.0 0.0099 15.3 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIY46521.1 - 0.026 14.0 0.1 0.053 13.0 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIY46521.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sedlin_N PF04628.13 KIY46523.1 - 8e-31 106.9 0.0 1.9e-30 105.7 0.0 1.5 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KIY46523.1 - 5.8e-08 32.8 0.0 7.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Pkinase PF00069.25 KIY46524.1 - 7.9e-56 189.3 0.0 9.2e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46524.1 - 5.5e-30 104.5 0.1 7.5e-30 104.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY46524.1 - 0.00027 20.4 0.1 0.0011 18.3 0.1 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KIY46524.1 - 0.00047 19.8 0.2 0.0043 16.7 0.1 2.2 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KIY46524.1 - 0.0035 16.7 0.1 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY46524.1 - 0.0048 16.9 0.0 1.2 9.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KIY46524.1 - 0.015 14.9 0.1 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KIY46524.1 - 0.05 12.4 0.1 0.08 11.7 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_M3 PF01432.20 KIY46525.1 - 2.7e-131 439.0 0.0 3.5e-131 438.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KIY46525.1 - 0.086 12.5 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Enterotoxin_b PF01376.18 KIY46525.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain DUF1751 PF08551.10 KIY46526.1 - 0.018 15.6 3.3 0.018 15.6 3.3 2.5 3 1 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Ni_hydr_CYTB PF01292.20 KIY46526.1 - 0.043 13.4 9.6 1.6 8.3 1.2 3.5 2 2 1 3 3 3 0 Prokaryotic cytochrome b561 ORC6 PF05460.13 KIY46528.1 - 9.3 5.4 7.2 12 5.0 7.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) POP1 PF06978.11 KIY46529.1 - 2.7e-47 161.4 13.4 2.1e-25 89.9 1.7 2.5 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KIY46529.1 - 6.3e-30 103.4 0.2 6.3e-30 103.4 0.2 2.5 3 0 0 3 3 3 1 POPLD (NUC188) domain GCV_T PF01571.21 KIY46529.1 - 5.2e-06 26.0 0.0 0.053 12.9 0.0 2.6 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KIY46529.1 - 0.0074 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pkinase PF00069.25 KIY46530.1 - 9.3e-12 44.9 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46530.1 - 2e-05 24.0 0.0 0.00012 21.4 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY46530.1 - 0.085 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPP_enzyme_N PF02776.18 KIY46531.1 - 2.4e-29 102.2 0.0 1.7e-28 99.4 0.0 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIY46531.1 - 1.9e-15 56.8 0.0 4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KIY46531.1 - 9.3e-10 38.5 0.0 2.8e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FA_desaturase PF00487.24 KIY46532.1 - 9.9e-20 71.4 27.7 9.9e-20 71.4 27.7 2.0 1 1 1 2 2 2 1 Fatty acid desaturase DUF4191 PF13829.6 KIY46533.1 - 2.8 7.2 7.9 13 5.0 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF423 PF04241.15 KIY46533.1 - 4.1 7.7 5.3 14 6.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF423) Pet127 PF08634.10 KIY46534.1 - 4.9e-100 334.5 0.0 6.7e-100 334.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 RRF PF01765.19 KIY46535.1 - 0.014 15.3 1.0 0.018 15.0 1.0 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Spc29 PF17082.5 KIY46535.1 - 0.062 13.1 0.1 0.068 13.0 0.1 1.0 1 0 0 1 1 1 0 Spindle Pole Component 29 MFS_1 PF07690.16 KIY46538.1 - 5.7e-33 114.3 25.0 8.1e-33 113.8 25.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3817 PF12823.7 KIY46538.1 - 0.17 12.7 4.2 1.9 9.4 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) DUF1514 PF07438.11 KIY46538.1 - 1.1 9.1 3.1 1.4 8.9 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) PHD PF00628.29 KIY46539.1 - 9.3e-07 28.6 3.8 9.3e-07 28.6 3.8 4.2 4 1 0 4 4 4 1 PHD-finger Pex26 PF07163.12 KIY46539.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Pex26 protein RdRP PF05183.12 KIY46540.1 - 1.2e-122 410.6 0.0 7.4e-98 328.7 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase Usp PF00582.26 KIY46541.1 - 3.3e-19 69.8 1.4 9.4e-19 68.3 0.0 2.3 2 0 0 2 2 2 1 Universal stress protein family Acetyltransf_CG PF14542.6 KIY46541.1 - 0.068 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribosomal_S19e PF01090.19 KIY46542.1 - 6.5e-58 194.3 0.1 7.5e-58 194.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e NAD_binding_6 PF08030.12 KIY46543.1 - 8.1e-16 58.5 0.0 8.8e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KIY46543.1 - 3e-14 53.2 7.4 3e-14 53.2 7.4 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIY46543.1 - 5.1e-14 52.3 0.0 1.5e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain adh_short PF00106.25 KIY46544.1 - 4.9e-26 91.4 0.0 7e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY46544.1 - 3.9e-19 69.2 0.0 5e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KIY46544.1 - 1.1e-07 31.9 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY46544.1 - 0.00032 20.2 0.0 0.00068 19.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIY46544.1 - 0.042 13.4 0.2 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 NmrA-like family Nbl1_Borealin_N PF10444.9 KIY46545.1 - 1.1e-09 37.8 1.0 2.3e-09 36.7 1.0 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Pkinase PF00069.25 KIY46546.1 - 4.2e-29 101.7 0.0 5.2e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46546.1 - 1e-19 70.9 0.0 1.3e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY46546.1 - 0.00011 21.6 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY46546.1 - 0.00092 18.1 0.0 0.0011 17.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY46546.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KIY46546.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KIY46546.1 - 0.18 11.4 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 RIO1 family MgsA_C PF12002.8 KIY46547.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.0 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal F-box-like PF12937.7 KIY46548.1 - 2.7e-10 40.0 0.2 3.7e-09 36.3 0.2 2.4 1 1 0 1 1 1 1 F-box-like Fer4_20 PF14691.6 KIY46548.1 - 0.085 12.6 0.0 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster F-box PF00646.33 KIY46548.1 - 0.2 11.6 1.5 12 6.0 0.4 2.5 2 0 0 2 2 2 0 F-box domain 3Beta_HSD PF01073.19 KIY46549.1 - 9.9e-66 221.6 0.0 2.2e-59 200.8 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIY46549.1 - 5.1e-34 117.8 0.0 7.6e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY46549.1 - 6.3e-18 65.3 0.0 2.6e-14 53.4 0.0 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIY46549.1 - 4.9e-13 48.8 0.0 6.9e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIY46549.1 - 2e-12 47.4 0.1 3.5e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIY46549.1 - 3.6e-09 36.2 0.0 3.9e-06 26.2 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KIY46549.1 - 2.2e-06 27.0 0.9 8.9e-06 25.0 0.9 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KIY46549.1 - 0.011 16.0 0.2 0.021 15.1 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 KIY46549.1 - 0.1 12.5 0.5 1.2 9.1 0.5 2.3 1 1 0 1 1 1 0 KR domain AF-4 PF05110.13 KIY46550.1 - 0.28 9.2 12.6 0.36 8.9 12.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Plavaka PF18759.1 KIY46552.1 - 2.8e-10 39.9 0.2 2.9e-09 36.6 0.0 2.3 2 1 0 2 2 2 1 Plavaka transposase gag-asp_proteas PF13975.6 KIY46557.1 - 0.00011 22.7 0.0 0.00031 21.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Host_attach PF10116.9 KIY46557.1 - 0.015 15.9 0.7 0.027 15.1 0.7 1.5 1 0 0 1 1 1 0 Protein required for attachment to host cells p450 PF00067.22 KIY46558.1 - 1.6e-72 244.7 0.0 3.5e-72 243.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SEN1_N PF12726.7 KIY46559.1 - 2.4e-113 379.9 6.2 3.6e-113 379.3 6.2 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_12 PF13087.6 KIY46559.1 - 1.1e-60 204.6 0.0 2.3e-60 203.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY46559.1 - 2.4e-59 201.3 0.7 2.4e-59 201.3 0.7 2.5 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KIY46559.1 - 4.6e-11 42.8 0.1 6e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIY46559.1 - 7.6e-08 32.8 0.0 2.4e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIY46559.1 - 1.6e-05 24.8 0.0 1.6 8.4 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KIY46559.1 - 0.00018 22.1 0.5 0.00055 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KIY46559.1 - 0.0012 18.9 0.4 0.015 15.3 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit GAS PF13851.6 KIY46559.1 - 0.012 14.9 3.8 0.03 13.7 3.8 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_22 PF13401.6 KIY46559.1 - 0.027 14.7 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KIY46559.1 - 0.041 13.6 0.0 0.4 10.4 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.29 KIY46559.1 - 0.043 14.2 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY46559.1 - 0.055 13.8 2.2 0.13 12.6 0.4 2.7 2 1 0 2 2 1 0 AAA ATPase domain DUF2075 PF09848.9 KIY46559.1 - 0.064 12.5 0.5 2.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) PhnH PF05845.12 KIY46559.1 - 0.072 12.8 0.2 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial phosphonate metabolism protein (PhnH) UvrD-helicase PF00580.21 KIY46559.1 - 0.28 10.7 1.5 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Glyco_transf_28 PF03033.20 KIY46560.1 - 3e-18 66.2 0.0 7.4e-18 64.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KIY46560.1 - 0.00029 19.7 0.2 0.00061 18.7 0.2 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIY46560.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain ATXN-1_C PF12547.8 KIY46560.1 - 0.17 12.2 0.6 3.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator Mem_trans PF03547.18 KIY46561.1 - 1.2e-15 56.9 3.6 5.4e-15 54.7 2.8 2.0 1 1 0 1 1 1 1 Membrane transport protein TMEM173 PF15009.6 KIY46561.1 - 0.1 11.8 1.3 0.13 11.4 0.1 1.8 2 1 1 3 3 3 0 Transmembrane protein 173 Fungal_trans PF04082.18 KIY46562.1 - 2.3e-26 92.4 0.0 3.9e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.22 KIY46565.1 - 1.2e-112 377.4 0.0 1.6e-112 377.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.24 KIY46566.1 - 7.2e-108 361.3 27.4 8.4e-108 361.1 27.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY46566.1 - 1.3e-22 80.2 31.1 1.4e-22 80.1 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S19 PF00203.21 KIY46569.1 - 7.3e-26 89.9 0.0 9.1e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Exostosin PF03016.15 KIY46570.1 - 0.067 12.4 0.1 0.075 12.2 0.1 1.1 1 0 0 1 1 1 0 Exostosin family Pkinase PF00069.25 KIY46572.1 - 2.2e-62 210.8 0.0 5.7e-62 209.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46572.1 - 2.3e-35 122.2 0.0 3.6e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KIY46572.1 - 7.4e-21 74.0 21.3 3.8e-13 49.3 4.9 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KIY46572.1 - 1.2e-20 73.1 27.9 3.1e-12 46.2 10.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KIY46572.1 - 7.8e-10 39.3 4.0 8e-10 39.3 0.8 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KIY46572.1 - 1e-05 25.8 0.1 1.9e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 KIY46572.1 - 0.041 12.8 0.1 0.079 11.9 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain C1_2 PF03107.16 KIY46572.1 - 0.057 13.7 22.4 0.37 11.1 8.0 2.4 2 0 0 2 2 2 0 C1 domain Kinase-like PF14531.6 KIY46572.1 - 0.078 12.3 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Kinase-like PP2C PF00481.21 KIY46573.1 - 2e-17 63.7 0.0 8.7e-16 58.3 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIY46573.1 - 5.7e-05 22.8 0.0 0.00012 21.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KIY46573.1 - 0.00014 21.8 0.1 0.013 15.4 0.0 3.2 4 0 0 4 4 4 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KIY46574.1 - 2.6e-12 46.9 0.0 1.4e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIY46574.1 - 1.5e-06 28.0 0.1 1.2e-05 25.1 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KIY46574.1 - 0.00056 19.9 0.1 0.019 14.9 0.0 2.9 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) FAA_hydrolase PF01557.18 KIY46574.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family DASH_Dad1 PF08649.10 KIY46578.1 - 4.1e-23 81.3 0.4 4.9e-23 81.1 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KIY46578.1 - 0.019 14.9 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 Scm3 PF10384.9 KIY46579.1 - 2.5e-10 39.9 0.0 7e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 PRA-PH PF01503.17 KIY46579.1 - 0.08 13.4 1.2 4.7 7.7 0.1 2.7 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DIOX_N PF14226.6 KIY46580.1 - 1.1e-24 87.4 0.0 1.8e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY46580.1 - 1.4e-13 51.2 0.0 3.1e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HMG_box PF00505.19 KIY46581.1 - 0.27 11.7 2.6 0.76 10.2 0.1 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box DUF2534 PF10749.9 KIY46582.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) F-box-like PF12937.7 KIY46584.1 - 9.8e-08 31.8 4.6 1.5e-07 31.2 0.2 3.0 3 0 0 3 3 3 1 F-box-like GRAM PF02893.20 KIY46584.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 GRAM domain Cep57_MT_bd PF06657.13 KIY46586.1 - 2.6e-25 88.7 0.1 2.6e-25 88.7 0.1 3.8 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Chorion_3 PF05387.11 KIY46586.1 - 0.013 15.1 0.3 0.013 15.1 0.3 1.8 2 0 0 2 2 2 0 Chorion family 3 Synaptonemal_3 PF15191.6 KIY46586.1 - 0.065 13.0 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Phage_GPO PF05929.11 KIY46586.1 - 8.4 5.9 7.9 31 4.1 0.0 2.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Endosulfine PF04667.17 KIY46587.1 - 2.2e-24 85.4 0.7 3.8e-24 84.6 0.2 1.6 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Transp_cyt_pur PF02133.15 KIY46588.1 - 2.8e-91 306.5 27.8 3.6e-91 306.1 27.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin F-box-like PF12937.7 KIY46590.1 - 3.1e-08 33.4 0.3 1.3e-07 31.4 0.3 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY46590.1 - 0.011 16.1 0.0 23 5.6 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) RasGEF PF00617.19 KIY46592.1 - 6.3e-60 202.4 0.3 1.2e-59 201.5 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY46592.1 - 6.3e-19 68.2 0.9 1.5e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif RIBIOP_C PF04950.12 KIY46594.1 - 1.1e-87 294.2 0.0 1.1e-87 294.2 0.0 2.2 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KIY46594.1 - 3.5e-30 103.9 0.0 1.1e-29 102.3 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KIY46594.1 - 7.3e-06 26.5 0.0 2.9e-05 24.5 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY46594.1 - 2.8e-05 24.4 0.0 6.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KIY46594.1 - 5.5e-05 22.8 0.0 0.015 14.9 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KIY46594.1 - 7.8e-05 22.9 1.1 0.00023 21.3 0.0 2.4 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 KIY46594.1 - 0.00019 21.9 2.3 0.0015 19.1 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KIY46594.1 - 0.0011 19.4 0.0 0.0029 18.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KIY46594.1 - 0.0011 19.0 0.1 0.0046 17.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KIY46594.1 - 0.0033 17.4 0.0 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIY46594.1 - 0.0038 16.5 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIY46594.1 - 0.0064 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase PduV-EutP PF10662.9 KIY46594.1 - 0.011 15.5 0.1 0.054 13.2 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KIY46594.1 - 0.012 16.2 8.5 3.6 8.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIY46594.1 - 0.012 16.2 0.0 0.012 16.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIY46594.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KIY46594.1 - 0.025 14.2 0.1 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KIY46594.1 - 0.03 14.0 0.0 0.098 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIY46594.1 - 0.031 14.6 0.1 0.066 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIY46594.1 - 0.031 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KIY46594.1 - 0.051 13.8 0.0 0.051 13.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KIY46594.1 - 0.051 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Roc PF08477.13 KIY46594.1 - 0.054 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIY46594.1 - 0.057 13.3 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_17 PF13207.6 KIY46594.1 - 0.067 13.6 0.1 0.067 13.6 0.1 3.1 3 0 0 3 3 1 0 AAA domain AAA_25 PF13481.6 KIY46594.1 - 0.078 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIY46594.1 - 0.082 12.7 11.4 0.4 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain HsbA PF12296.8 KIY46595.1 - 0.0015 18.9 7.3 0.0024 18.3 7.3 1.4 1 1 0 1 1 1 1 Hydrophobic surface binding protein A LXG PF04740.12 KIY46595.1 - 0.024 14.4 1.6 0.17 11.6 1.5 2.0 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF948 PF06103.11 KIY46595.1 - 0.064 13.5 5.2 0.072 13.4 0.6 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Exo70 PF03081.15 KIY46595.1 - 0.18 10.9 0.5 0.28 10.2 0.5 1.4 1 1 0 1 1 1 0 Exo70 exocyst complex subunit DUF4603 PF15376.6 KIY46595.1 - 0.2 9.0 0.1 0.22 8.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Phage_holin_2_4 PF16082.5 KIY46595.1 - 0.95 9.2 4.0 9.8 6.0 0.6 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like F-box-like PF12937.7 KIY46596.1 - 0.00011 22.0 1.0 0.00044 20.1 1.0 2.1 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY46596.1 - 0.0015 18.4 0.4 0.0033 17.4 0.4 1.6 1 0 0 1 1 1 1 F-box-like domain cNMP_binding PF00027.29 KIY46598.1 - 2.7e-31 107.5 0.1 5.5e-14 52.0 0.1 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain RIIa PF02197.17 KIY46598.1 - 1.4e-08 34.3 0.1 4.7e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DbpA PF03880.15 KIY46598.1 - 0.17 11.9 0.3 0.31 11.0 0.3 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain RBM1CTR PF08081.11 KIY46598.1 - 3.1 7.9 7.0 24 5.1 0.3 2.6 2 0 0 2 2 2 0 RBM1CTR (NUC064) family PI31_Prot_N PF11566.8 KIY46599.1 - 5.5e-41 140.1 0.1 6.6e-41 139.8 0.1 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KIY46599.1 - 3.4e-13 50.6 14.4 3.4e-13 50.6 14.4 3.1 3 0 0 3 3 3 1 PI31 proteasome regulator LNS2 PF08235.13 KIY46600.1 - 3.7e-99 330.8 0.0 5.2e-99 330.3 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KIY46600.1 - 6.8e-36 122.3 0.0 1.3e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KIY46600.1 - 0.028 14.0 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) ubiquitin PF00240.23 KIY46601.1 - 0.00077 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KIY46601.1 - 0.033 14.7 0.0 0.068 13.7 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain FG-GAP_2 PF14312.6 KIY46601.1 - 0.04 14.2 0.3 0.082 13.2 0.3 1.4 1 0 0 1 1 1 0 FG-GAP repeat Complex1_LYR PF05347.15 KIY46602.1 - 3.2e-08 33.5 0.6 5.1e-08 32.8 0.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRN3 PF05327.11 KIY46603.1 - 2.6e-193 643.6 0.4 3.8e-193 643.1 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Cnd2 PF05786.14 KIY46603.1 - 0.22 10.2 2.3 0.38 9.3 2.3 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 IU_nuc_hydro PF01156.19 KIY46604.1 - 1.4e-85 287.6 0.0 1.6e-85 287.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Peptidase_S28 PF05577.12 KIY46605.1 - 2.8e-53 181.3 0.1 3.5e-53 180.9 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIY46605.1 - 0.0031 17.0 0.0 0.0072 15.8 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Acetyltransf_1 PF00583.25 KIY46606.1 - 1.4e-07 31.7 0.0 2.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY46606.1 - 1.6e-05 25.2 0.0 2.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIY46606.1 - 0.0027 18.4 0.0 0.0033 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY46606.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.32 KIY46607.1 - 2.1e-09 37.8 9.8 0.033 15.0 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY46607.1 - 1.9e-06 28.1 0.0 0.33 11.3 0.0 4.6 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY46607.1 - 1.7e-05 24.8 0.0 0.059 13.2 0.0 2.5 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIY46607.1 - 0.0028 17.5 0.0 0.46 10.5 0.0 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KIY46607.1 - 0.037 13.1 0.0 3.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region Alg6_Alg8 PF03155.15 KIY46608.1 - 8.1e-170 565.9 30.9 9.4e-170 565.7 30.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family VMA21 PF09446.10 KIY46609.1 - 6.2e-12 45.4 8.0 9.2e-12 44.9 8.0 1.3 1 0 0 1 1 1 1 VMA21-like domain KCH PF16944.5 KIY46610.1 - 6.8e-88 294.7 11.1 8.2e-88 294.4 11.1 1.1 1 0 0 1 1 1 1 Fungal potassium channel MMR_HSR1_Xtn PF16897.5 KIY46611.1 - 4.6e-38 129.5 1.1 3e-37 126.9 0.7 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KIY46611.1 - 1.1e-24 86.2 0.0 1.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KIY46611.1 - 1e-18 67.5 0.0 2.3e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY46611.1 - 1.8e-08 34.1 0.2 5.5e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KIY46611.1 - 0.036 13.1 0.8 0.1 11.6 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MFS_1 PF07690.16 KIY46612.1 - 7e-27 94.3 58.5 2.6e-20 72.7 22.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY46612.1 - 6.6e-05 22.0 5.6 6.6e-05 22.0 5.6 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2834 PF11196.8 KIY46612.1 - 0.0036 17.6 1.7 3.3 8.1 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) Sec63 PF02889.16 KIY46613.1 - 3.6e-76 255.7 0.0 5.7e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KIY46613.1 - 1.7e-21 76.8 1.7 2.1e-15 56.9 0.5 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY46613.1 - 8e-06 26.2 0.0 0.00044 20.6 0.0 3.6 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY46613.1 - 9.8e-06 25.7 0.0 0.001 19.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIY46613.1 - 0.048 13.4 0.3 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIY46613.1 - 0.051 13.8 0.1 9.6 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain GST_N_3 PF13417.6 KIY46614.1 - 3.2e-18 65.9 0.1 5.4e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY46614.1 - 9.2e-17 61.2 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY46614.1 - 1.7e-11 44.2 0.0 3.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY46614.1 - 2.6e-08 34.0 0.0 4.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY46614.1 - 0.00012 22.2 0.0 0.00077 19.6 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY46614.1 - 0.00015 21.7 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Herpes_UL82_83 PF05784.11 KIY46614.1 - 0.026 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus EMC3_TMCO1 PF01956.16 KIY46616.1 - 2.9e-47 160.6 7.7 1.2e-46 158.5 7.7 1.8 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EF-hand_7 PF13499.6 KIY46617.1 - 2.1e-25 88.9 10.5 1.1e-17 64.2 1.4 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KIY46617.1 - 1.2e-23 80.8 14.4 9.6e-08 31.1 0.0 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KIY46617.1 - 6.7e-21 72.4 9.8 5.8e-06 25.8 0.3 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KIY46617.1 - 5.3e-14 51.8 9.8 8.4e-06 25.5 1.2 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KIY46617.1 - 2e-09 36.5 15.6 0.0038 16.7 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 KIY46617.1 - 2.5e-06 27.4 8.7 0.04 13.9 0.1 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIY46617.1 - 0.0003 21.1 4.2 0.14 12.5 0.6 3.5 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KIY46617.1 - 0.00084 19.6 3.4 0.54 10.6 0.4 3.5 2 1 1 3 3 3 2 EF-hand domain Pan3_PK PF18101.1 KIY46617.1 - 0.088 12.8 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Pan3 Pseudokinase domain S10_plectin PF03501.15 KIY46617.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain Caleosin PF05042.13 KIY46617.1 - 0.17 11.8 5.2 8.6 6.3 0.0 3.3 2 1 1 4 4 4 0 Caleosin related protein HAT PF02184.16 KIY46618.1 - 6.2 6.9 5.0 16 5.6 0.3 2.7 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat DUF1932 PF09130.11 KIY46619.1 - 0.13 12.2 0.8 0.24 11.4 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) WD40 PF00400.32 KIY46620.1 - 0.00016 22.4 0.0 0.096 13.6 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY46620.1 - 0.0072 16.6 0.0 1.2 9.5 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 KIY46620.1 - 0.013 14.6 0.1 0.097 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) DASH_Dad4 PF08650.10 KIY46621.1 - 9.9e-25 86.3 2.6 1.1e-24 86.1 2.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 ATE_C PF04377.15 KIY46622.1 - 6.8e-46 156.2 0.2 1e-45 155.6 0.2 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KIY46622.1 - 2.1e-22 79.3 6.6 4.4e-22 78.3 6.6 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Peptidase_M18 PF02127.15 KIY46623.1 - 2.3e-155 517.7 0.0 2.6e-155 517.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KIY46623.1 - 7e-07 28.6 0.0 0.00025 20.2 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase SurA_N_3 PF13624.6 KIY46623.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain GFA PF04828.14 KIY46624.1 - 2e-19 69.7 0.8 3e-19 69.1 0.8 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme GFA PF04828.14 KIY46625.1 - 2.2e-22 79.2 0.8 3e-22 78.8 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FemAB_like PF04339.12 KIY46625.1 - 0.057 12.5 0.0 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition zf-B_box PF00643.24 KIY46625.1 - 0.21 11.8 3.5 0.76 10.0 0.1 2.4 2 0 0 2 2 2 0 B-box zinc finger V-SNARE PF05008.15 KIY46626.1 - 6.8e-19 68.0 5.4 6.8e-19 68.0 5.4 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KIY46626.1 - 2.7e-13 50.0 6.9 2.7e-13 50.0 6.9 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KIY46626.1 - 0.0032 17.3 0.7 0.0032 17.3 0.7 1.9 2 1 0 2 2 2 1 Sec20 SNARE PF05739.19 KIY46626.1 - 0.006 16.6 1.2 0.006 16.6 1.2 2.0 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.21 KIY46626.1 - 0.011 15.6 0.2 0.028 14.2 0.2 1.9 1 0 0 1 1 1 0 Synaptobrevin Ferlin_C PF16165.5 KIY46626.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF1640 PF07798.11 KIY46626.1 - 0.062 13.3 11.5 0.47 10.5 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) SF1-HH PF16275.5 KIY46626.1 - 0.093 13.1 3.3 0.12 12.7 0.4 2.5 1 1 0 2 2 2 0 Splicing factor 1 helix-hairpin domain Prominin PF05478.11 KIY46626.1 - 0.094 10.7 3.8 0.15 10.0 3.8 1.3 1 1 0 1 1 1 0 Prominin RIFIN PF02009.16 KIY46626.1 - 0.12 12.3 5.5 0.032 14.1 2.2 1.6 1 1 0 2 2 2 0 Rifin DUF1366 PF07104.11 KIY46626.1 - 0.12 12.0 1.4 0.35 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) DUF3619 PF12279.8 KIY46626.1 - 0.14 12.4 5.4 0.18 12.1 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3619) Laminin_II PF06009.12 KIY46626.1 - 0.15 12.1 4.5 0.7 9.9 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II Orf78 PF06024.12 KIY46626.1 - 0.18 12.1 2.0 0.81 10.0 0.3 2.2 2 0 0 2 2 2 0 Orf78 (ac78) TBCA PF02970.16 KIY46626.1 - 0.69 10.3 12.0 1.8 9.0 0.3 2.9 2 1 0 2 2 2 0 Tubulin binding cofactor A MPS2 PF17060.5 KIY46626.1 - 1.3 8.2 8.3 4.8 6.3 8.3 1.9 1 1 0 1 1 1 0 Monopolar spindle protein 2 Exonuc_VII_L PF02601.15 KIY46626.1 - 1.4 8.4 11.9 9.7 5.6 11.9 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Spore_III_AB PF09548.10 KIY46626.1 - 7.9 6.6 9.3 3.2 7.9 0.9 2.6 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Sugar_tr PF00083.24 KIY46627.1 - 1.5e-110 370.2 26.0 1.8e-110 369.9 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY46627.1 - 1.4e-19 70.3 40.4 6.7e-16 58.2 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY46627.1 - 0.0001 20.9 1.8 0.0001 20.9 1.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Herpes_LMP1 PF05297.11 KIY46627.1 - 1.1 8.4 4.8 2.1 7.4 4.8 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) OATP PF03137.20 KIY46627.1 - 2 6.6 12.4 0.2 9.9 1.5 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S24 PF00717.23 KIY46628.1 - 3e-08 33.5 0.0 9.9e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KIY46628.1 - 0.0013 18.5 0.0 0.47 10.3 0.0 2.9 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 WD40 PF00400.32 KIY46629.1 - 2.4e-55 183.2 20.0 5.8e-07 30.1 0.2 12.1 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY46629.1 - 2.8e-23 82.0 5.8 9.2e-06 25.9 0.0 9.3 5 3 4 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KIY46629.1 - 9.5e-22 77.3 0.8 1.8e-21 76.5 0.8 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 KIY46629.1 - 1.4e-07 30.5 3.6 0.34 9.5 0.1 5.2 4 2 1 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIY46629.1 - 1.5e-05 24.2 6.3 7.3 5.4 0.0 6.4 5 2 3 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIY46629.1 - 7.9e-05 22.1 0.0 1.1 8.5 0.0 4.2 4 1 1 5 5 5 2 WD40-like domain Nucleoporin_N PF08801.11 KIY46629.1 - 0.00025 19.9 2.5 1.1 7.9 0.0 5.1 3 2 2 6 6 6 1 Nup133 N terminal like RAB3GAP2_N PF14655.6 KIY46629.1 - 0.006 15.9 1.3 1.5 8.0 0.0 3.5 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ELYS-bb PF16687.5 KIY46629.1 - 0.023 13.3 0.0 4.5 5.8 0.0 3.3 3 1 1 4 4 4 0 beta-propeller of ELYS nucleoporin eIF2A PF08662.11 KIY46629.1 - 0.072 13.0 0.1 9.2 6.1 0.0 3.7 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KIY46629.1 - 6.3 5.6 6.9 35 3.2 0.0 4.1 4 2 2 6 6 6 0 Partner and localizer of BRCA2 WD40 domain DPBB_1 PF03330.18 KIY46631.1 - 1.3e-06 28.6 0.0 2.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Fungal_trans PF04082.18 KIY46632.1 - 1.3e-16 60.5 0.0 2.9e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY46632.1 - 6e-05 23.1 13.3 0.00011 22.3 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KIY46633.1 - 8.1e-08 32.0 1.4 2.1e-07 30.7 1.4 1.8 1 0 0 1 1 1 1 F-box-like Glyco_trans_4_4 PF13579.6 KIY46633.1 - 0.037 14.5 1.2 0.11 13.0 1.2 1.8 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Syntaxin-18_N PF10496.9 KIY46634.1 - 8.2e-13 48.4 3.4 1.7e-12 47.4 0.1 2.7 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KIY46634.1 - 0.0025 17.8 4.3 0.003 17.5 0.0 2.9 3 0 0 3 3 3 1 SNARE domain SNARE_assoc PF09335.11 KIY46635.1 - 8.4e-14 52.1 4.6 8.4e-14 52.1 4.6 2.7 3 1 0 3 3 3 1 SNARE associated Golgi protein DUF2681 PF10883.8 KIY46635.1 - 0.96 9.9 3.1 17 5.9 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF2207 PF09972.9 KIY46635.1 - 2.8 6.6 6.4 0.99 8.1 2.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.20 KIY46635.1 - 5.6 6.4 7.7 10 5.6 4.8 2.3 2 1 0 2 2 2 0 E1-E2 ATPase Cys_Met_Meta_PP PF01053.20 KIY46637.1 - 7.3e-62 209.1 0.0 1.3e-61 208.2 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ssu72 PF04722.13 KIY46638.1 - 3.8e-75 251.7 0.0 4.3e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Proteasome PF00227.26 KIY46639.1 - 6.5e-61 205.1 0.0 9.4e-61 204.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY46639.1 - 2.6e-08 33.4 0.2 7.5e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_clus PF00172.18 KIY46640.1 - 7.3e-06 26.0 10.8 1.4e-05 25.1 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KIY46641.1 - 3.4e-166 553.3 0.5 3.9e-166 553.2 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5063 PF16702.5 KIY46641.1 - 0.067 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) DUF2415 PF10313.9 KIY46642.1 - 2.2e-07 30.7 0.2 6.7e-07 29.1 0.2 1.9 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KIY46642.1 - 7.5e-05 23.4 4.5 1.6 9.7 0.1 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.12 KIY46642.1 - 0.0031 17.4 3.5 2 8.5 0.2 3.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIY46642.1 - 0.0039 17.5 0.0 0.67 10.3 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIY46642.1 - 0.065 12.6 0.1 0.36 10.1 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIY46642.1 - 0.24 10.3 0.1 0.66 8.9 0.1 1.7 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sulfatase PF00884.23 KIY46643.1 - 6.3e-51 173.6 0.3 1e-50 172.9 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Ribonuclease_3 PF00636.26 KIY46644.1 - 8.9e-49 164.5 0.0 4.1e-23 82.0 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIY46644.1 - 8.3e-26 90.7 0.0 9.4e-08 32.3 0.0 4.4 4 0 0 4 4 4 4 Ribonuclease-III-like PAZ PF02170.22 KIY46644.1 - 1.8e-07 31.0 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Dicer_dimer PF03368.14 KIY46644.1 - 1e-06 28.8 0.0 3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KIY46644.1 - 0.0029 18.0 0.0 0.0062 16.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNR_Alpha PF17975.1 KIY46644.1 - 0.02 15.4 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain dsrm PF00035.26 KIY46645.1 - 5.5e-09 36.6 0.0 1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif SopA_C PF13979.6 KIY46645.1 - 0.028 14.2 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 SopA-like catalytic domain DUF2264 PF10022.9 KIY46646.1 - 3.5e-141 470.4 0.1 4.2e-141 470.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) NMO PF03060.15 KIY46647.1 - 3.1e-50 171.4 0.3 4.5e-50 170.9 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIY46647.1 - 1.1e-06 27.9 0.3 5.2e-06 25.7 0.3 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIY46647.1 - 0.0089 15.1 3.9 0.014 14.5 3.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AA_kinase PF00696.28 KIY46647.1 - 0.036 13.6 0.0 0.097 12.2 0.0 1.7 1 1 0 1 1 1 0 Amino acid kinase family COX7C PF02935.16 KIY46649.1 - 1.8e-14 53.7 1.2 2.3e-14 53.4 1.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Btz PF09405.10 KIY46650.1 - 1.9e-09 37.9 0.3 1.9e-09 37.9 0.3 2.2 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.25 KIY46651.1 - 2.1e-46 158.5 0.0 2.6e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46651.1 - 3.2e-29 102.0 0.0 4e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY46651.1 - 2.1e-08 33.8 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY46651.1 - 5.2e-05 23.3 0.1 0.00067 19.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY46651.1 - 0.0025 16.8 0.0 0.0032 16.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY46651.1 - 0.0051 16.2 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family dsrm PF00035.26 KIY46652.1 - 1.7e-05 25.5 0.0 2.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 KIY46653.1 - 3.7e-08 34.0 0.0 4.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF4031 PF13223.6 KIY46653.1 - 0.081 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) BTB PF00651.31 KIY46654.1 - 3.1e-08 33.8 0.0 1.3e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain CAP_GLY PF01302.25 KIY46654.1 - 0.00034 20.6 8.4 0.038 14.0 5.8 3.8 3 1 0 3 3 3 1 CAP-Gly domain ESCRT-II PF05871.12 KIY46655.1 - 1.9e-34 118.9 1.2 2.6e-34 118.5 1.2 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Amidase PF01425.21 KIY46656.1 - 1.7e-56 192.1 0.0 1.3e-51 176.0 0.0 2.1 2 0 0 2 2 2 2 Amidase gag-asp_proteas PF13975.6 KIY46660.1 - 0.0012 19.4 0.0 0.0037 17.8 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIY46660.1 - 0.13 12.1 0.1 0.18 11.6 0.1 1.4 1 1 0 1 1 1 0 Aspartyl protease YfdX PF10938.8 KIY46661.1 - 0.089 12.7 0.5 0.12 12.3 0.5 1.2 1 0 0 1 1 1 0 YfdX protein Chitin_synth_2 PF03142.15 KIY46663.1 - 7.6e-21 74.3 0.0 9.1e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Heme_oxygenase PF01126.20 KIY46664.1 - 3.2e-20 72.8 0.0 1.4e-19 70.7 0.0 2.0 1 1 0 1 1 1 1 Heme oxygenase GlgX_C PF18390.1 KIY46666.1 - 0.04 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain Flavoprotein PF02441.19 KIY46667.1 - 7.2e-52 175.3 0.0 8.3e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Abhydrolase_6 PF12697.7 KIY46668.1 - 1.6e-11 45.3 6.0 1.6e-11 45.3 6.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY46668.1 - 1.8e-11 44.2 0.0 3.9e-08 33.3 0.0 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold CMD PF02627.20 KIY46668.1 - 2.5e-09 37.1 0.2 5.9e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Hydrolase_4 PF12146.8 KIY46668.1 - 6.7e-07 28.8 0.0 4.9e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIY46668.1 - 0.015 14.0 0.0 0.036 12.8 0.0 1.5 1 1 0 1 1 1 0 Ndr family Forkhead PF00250.18 KIY46669.1 - 1.3e-15 57.4 0.0 2.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain NmrA PF05368.13 KIY46670.1 - 1.7e-26 93.2 0.0 2.4e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY46670.1 - 2.9e-11 43.6 0.0 4.1e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY46670.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mob1_phocein PF03637.17 KIY46671.1 - 1.4e-65 220.4 1.7 1.7e-65 220.2 1.7 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF5127 PF17168.4 KIY46672.1 - 4.2e-79 265.5 7.2 4.2e-79 265.5 7.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIY46672.1 - 1.9e-77 258.8 0.1 9.3e-77 256.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIY46672.1 - 1.6e-49 168.5 1.3 1.6e-49 168.5 1.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIY46672.1 - 1.1e-09 37.7 0.7 4.1e-09 35.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Pollen_allerg_1 PF01357.21 KIY46672.1 - 0.28 11.3 1.5 5 7.2 0.1 3.2 3 0 0 3 3 3 0 Pollen allergen zf-CCHH PF10283.9 KIY46673.1 - 0.035 14.1 4.5 0.083 12.9 4.5 1.7 1 0 0 1 1 1 0 PBZ domain CDC37_N PF03234.14 KIY46674.1 - 1.1e-37 129.8 0.6 1.1e-37 129.8 0.6 2.4 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KIY46674.1 - 7.9e-25 87.1 0.0 2.8e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KIY46674.1 - 2.1e-15 56.7 2.5 2.8e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain RAI1 PF08652.11 KIY46675.1 - 1.2e-20 73.5 0.0 2.8e-20 72.3 0.0 1.6 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease adh_short PF00106.25 KIY46676.1 - 6.3e-32 110.6 0.0 8.9e-28 97.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY46676.1 - 4.6e-19 68.9 0.0 1.4e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY46676.1 - 3.7e-10 40.0 0.1 6.8e-10 39.2 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY46676.1 - 2.2e-06 27.3 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIY46676.1 - 0.0005 19.3 0.0 0.00077 18.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KIY46676.1 - 0.0018 18.5 0.1 0.0031 17.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KIY46676.1 - 0.0043 16.5 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIY46676.1 - 0.032 14.1 0.2 0.048 13.5 0.2 1.2 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_7 PF13241.6 KIY46676.1 - 0.094 13.2 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_4 PF07993.12 KIY46676.1 - 0.17 11.0 0.1 0.28 10.3 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein F-box-like PF12937.7 KIY46677.1 - 0.064 13.2 0.1 0.24 11.3 0.1 2.1 1 0 0 1 1 1 0 F-box-like DUF3605 PF12239.8 KIY46678.1 - 4.4e-28 98.5 0.0 1.1e-18 68.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) WD40 PF00400.32 KIY46680.1 - 0.016 16.0 5.3 0.15 13.0 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat CSN8_PSD8_EIF3K PF10075.9 KIY46681.1 - 0.11 12.5 0.2 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family MBOAT_2 PF13813.6 KIY46682.1 - 5.7e-11 42.5 2.1 5.7e-11 42.5 2.1 2.4 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Mit_KHE1 PF10173.9 KIY46682.1 - 0.54 10.3 1.4 0.96 9.5 1.4 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related SnoaL_2 PF12680.7 KIY46683.1 - 0.0072 17.0 0.0 0.0085 16.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.25 KIY46686.1 - 8.2e-45 153.2 0.0 1e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46686.1 - 1.4e-25 90.1 0.0 3.7e-25 88.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY46686.1 - 1.9e-09 37.2 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY46686.1 - 5.9e-05 23.1 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY46686.1 - 0.0014 17.5 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIY46686.1 - 0.054 13.1 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KIY46686.1 - 0.096 12.3 0.0 0.27 10.8 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY46686.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-H2C2_2 PF13465.6 KIY46689.1 - 0.00027 21.2 1.5 0.00092 19.5 1.5 1.9 1 0 0 1 1 1 1 Zinc-finger double domain DUF629 PF04780.12 KIY46689.1 - 0.86 8.1 4.0 1.7 7.1 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF629) OrfB_Zn_ribbon PF07282.11 KIY46690.1 - 1.4 8.9 3.5 0.64 10.0 0.4 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Rhodanese PF00581.20 KIY46691.1 - 7.9e-10 39.2 0.0 9.6e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF3767 PF12597.8 KIY46692.1 - 2.1e-15 56.4 0.3 2.4e-15 56.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Porin_3 PF01459.22 KIY46693.1 - 2e-72 243.9 5.6 2.2e-72 243.8 5.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF809 PF05663.11 KIY46693.1 - 0.032 14.4 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF809) NADH-u_ox-rdase PF10785.9 KIY46694.1 - 1.2e-26 93.2 0.1 1.7e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KIY46694.1 - 1.4e-12 47.4 0.0 2.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit F-box-like PF12937.7 KIY46695.1 - 4.8e-09 36.0 2.2 4.8e-09 36.0 2.2 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY46695.1 - 0.088 13.3 1.0 42 4.7 0.1 4.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) BTB PF00651.31 KIY46696.1 - 1.4e-06 28.5 0.0 2.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TPR_MLP1_2 PF07926.12 KIY46697.1 - 2.4e-26 92.3 24.3 2.4e-26 92.3 24.3 15.5 7 3 6 14 14 14 5 TPR/MLP1/MLP2-like protein MbeD_MobD PF04899.12 KIY46697.1 - 0.018 15.2 0.3 0.018 15.2 0.3 10.8 10 2 1 11 11 11 0 MbeD/MobD like APG6_N PF17675.1 KIY46697.1 - 0.022 15.3 0.8 0.022 15.3 0.8 17.6 3 3 13 16 16 16 0 Apg6 coiled-coil region MinE PF03776.14 KIY46697.1 - 0.023 14.7 0.1 0.22 11.5 0.1 2.9 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DUF382 PF04037.13 KIY46697.1 - 0.94 9.6 4.1 1.4 9.1 0.3 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF382) Peptidase_U57 PF05582.12 KIY46698.1 - 0.087 12.1 0.1 0.16 11.2 0.1 1.4 1 1 0 1 1 1 0 YabG peptidase U57 LAP1C PF05609.12 KIY46698.1 - 0.11 11.5 0.6 0.16 11.1 0.1 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Ysc84 PF04366.12 KIY46699.1 - 1.2e-45 154.4 0.0 1.8e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Sec7 PF01369.20 KIY46699.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Sec7 domain DUF1072 PF06380.11 KIY46700.1 - 2.6 8.0 6.0 0.27 11.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Phosducin PF02114.16 KIY46701.1 - 7.9e-14 51.2 0.0 5.4e-07 28.8 0.0 3.1 2 1 1 3 3 3 3 Phosducin GDI PF00996.18 KIY46702.1 - 5.4e-42 143.8 0.0 8.9e-42 143.1 0.0 1.3 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KIY46702.1 - 0.049 13.9 0.9 0.1 12.8 0.4 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KIY46702.1 - 0.063 13.1 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KIY46702.1 - 0.2 11.2 0.2 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2235 PF09994.9 KIY46703.1 - 2.7e-90 302.7 0.1 3.4e-90 302.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Kinesin PF00225.23 KIY46704.1 - 2.2e-91 306.3 0.0 2.6e-54 184.4 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KIY46704.1 - 9.9e-21 74.2 0.0 2e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_23 PF13476.6 KIY46704.1 - 4.1 7.9 11.5 4.3 7.8 2.7 2.6 3 0 0 3 3 3 0 AAA domain Lzipper-MIP1 PF14389.6 KIY46704.1 - 6.5 7.1 9.5 14 6.1 0.0 3.4 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Ras PF00071.22 KIY46706.1 - 2.2e-55 186.7 0.0 2.6e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY46706.1 - 8.6e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY46706.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIY46706.1 - 0.0032 16.9 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY46706.1 - 0.22 10.8 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Abhydrolase_1 PF00561.20 KIY46707.1 - 2.7e-19 69.8 0.0 6.8e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY46707.1 - 4.9e-16 60.0 0.0 5.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY46707.1 - 7.8e-14 51.5 0.1 4.4e-13 49.1 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KIY46707.1 - 0.0083 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KIY46707.1 - 0.009 15.9 0.1 0.21 11.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KIY46707.1 - 0.012 15.2 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 KIY46707.1 - 0.026 14.5 0.0 0.81 9.6 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KIY46707.1 - 0.032 13.7 0.1 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KIY46707.1 - 0.095 12.8 0.0 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain Dynamin_N PF00350.23 KIY46708.1 - 9e-19 68.1 0.0 2.1e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KIY46708.1 - 2.5e-13 50.1 0.0 1.9e-12 47.3 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY46708.1 - 2.1e-08 33.9 0.2 2e-07 30.8 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY46708.1 - 0.00014 21.8 0.7 0.098 12.6 0.2 2.6 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 KIY46708.1 - 0.0017 18.0 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KIY46708.1 - 0.016 15.4 0.8 1.4 9.2 0.0 3.0 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KIY46708.1 - 0.033 14.2 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 KIY46708.1 - 0.038 13.4 0.2 12 5.3 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_29 PF13555.6 KIY46708.1 - 0.039 13.7 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 KIY46708.1 - 0.08 12.0 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF2258 PF10015.9 KIY46708.1 - 0.094 12.9 0.0 0.37 11.0 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) AAA_18 PF13238.6 KIY46708.1 - 0.13 12.9 0.0 5.4 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KIY46708.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Septin MBOAT_2 PF13813.6 KIY46709.1 - 7.5e-14 51.8 2.8 7.5e-14 51.8 2.8 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family SAM_2 PF07647.17 KIY46710.1 - 3.2e-09 36.8 0.2 2.2e-08 34.1 0.0 2.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIY46710.1 - 0.00036 20.9 0.0 0.00085 19.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 KIY46710.1 - 0.074 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) IGR PF09597.10 KIY46710.1 - 0.081 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 IGR protein motif Smg4_UPF3 PF03467.15 KIY46711.1 - 2.5e-32 112.3 0.3 2.8e-32 112.1 0.3 1.0 1 0 0 1 1 1 1 Smg-4/UPF3 family Gag_p24 PF00607.20 KIY46711.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Cpn60_TCP1 PF00118.24 KIY46712.1 - 0.063 11.9 0.0 0.08 11.6 0.0 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Phage_integrase PF00589.22 KIY46713.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family MFS_1 PF07690.16 KIY46714.1 - 3.1e-20 72.4 35.2 3.8e-17 62.3 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-MYND PF01753.18 KIY46715.1 - 9.5e-11 41.6 3.4 4.8e-10 39.4 3.4 2.4 1 1 0 1 1 1 1 MYND finger FYRN PF05964.14 KIY46716.1 - 7.6e-19 67.3 0.3 1.3e-18 66.6 0.3 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 KIY46716.1 - 1.2e-15 57.4 0.0 2.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 F/Y rich C-terminus Transglut_core PF01841.19 KIY46717.1 - 1.6e-13 51.1 0.0 2.7e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily CN_hydrolase PF00795.22 KIY46718.1 - 1.2e-17 64.1 0.0 5.3e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DEAD PF00270.29 KIY46719.1 - 8e-17 61.6 0.0 2.4e-16 60.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY46719.1 - 8.1e-15 55.1 0.0 4.6e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIY46719.1 - 8.1e-07 29.7 1.0 8.1e-07 29.7 1.0 2.2 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 KIY46719.1 - 0.085 12.9 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Asp PF00026.23 KIY46720.1 - 2.3e-12 47.0 0.8 1.3e-09 37.9 0.8 2.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KIY46720.1 - 1.5e-08 35.1 0.0 0.092 13.3 0.0 3.3 3 0 0 3 3 3 3 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY46720.1 - 2.7e-06 27.9 0.2 0.1 13.3 0.1 3.1 2 1 0 2 2 2 2 Aspartyl protease RVP PF00077.20 KIY46720.1 - 0.00022 21.5 0.1 0.0046 17.2 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Q_salvage PF10343.9 KIY46721.1 - 3.2e-89 299.2 0.0 4.4e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Asp PF00026.23 KIY46723.1 - 2e-17 63.6 7.5 3.7e-14 52.9 7.5 3.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KIY46723.1 - 6.8e-05 23.4 0.2 0.0071 16.9 0.0 2.8 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY46723.1 - 0.00011 22.8 0.9 0.00047 20.7 0.5 2.3 2 0 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 KIY46723.1 - 0.032 14.5 2.0 1.1 9.5 0.2 2.3 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal YjeF_N PF03853.15 KIY46724.1 - 3.3e-40 137.8 0.0 4.1e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.25 KIY46724.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme zf-RING_2 PF13639.6 KIY46725.1 - 2.7e-11 43.6 2.8 6e-11 42.5 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KIY46725.1 - 1e-10 41.2 2.1 1e-10 41.2 2.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KIY46725.1 - 1.1e-06 28.4 0.9 1.9e-06 27.7 0.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain PA PF02225.22 KIY46725.1 - 4.6e-06 26.6 0.0 9.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 KIY46725.1 - 5.6e-06 26.1 2.5 1.1e-05 25.2 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY46725.1 - 9.2e-05 22.2 1.5 0.00018 21.3 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY46725.1 - 0.00012 22.3 5.9 0.00047 20.4 5.2 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIY46725.1 - 0.00013 21.9 2.2 0.0041 17.1 0.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY46725.1 - 0.00045 20.0 1.7 0.0011 18.7 1.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY46725.1 - 0.0048 16.7 1.9 0.0048 16.7 1.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KIY46725.1 - 0.0078 16.2 1.0 0.024 14.7 1.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIY46725.1 - 0.25 11.0 1.9 0.49 10.1 1.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PIF1 PF05970.14 KIY46726.1 - 0.00041 19.6 0.3 0.00092 18.5 0.1 1.5 2 0 0 2 2 2 1 PIF1-like helicase SH3_13 PF18335.1 KIY46726.1 - 0.017 14.9 0.3 0.027 14.3 0.3 1.3 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain VEG PF06257.11 KIY46726.1 - 0.069 13.2 0.2 1.2 9.2 0.1 2.4 2 1 0 2 2 2 0 Biofilm formation stimulator VEG PhnA PF03831.14 KIY46726.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 PhnA domain DUF3465 PF11948.8 KIY46726.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) YadA_anchor PF03895.15 KIY46726.1 - 0.21 11.7 0.6 0.34 11.0 0.6 1.3 1 0 0 1 1 1 0 YadA-like membrane anchor domain UEV PF05743.13 KIY46727.1 - 3.4e-33 114.1 0.0 5.6e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KIY46727.1 - 2.1e-27 94.9 0.2 3.7e-27 94.1 0.2 1.4 1 0 0 1 1 1 1 Vps23 core domain zf-C3H1 PF10650.9 KIY46728.1 - 0.0012 18.5 0.7 0.0021 17.7 0.7 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Epimerase PF01370.21 KIY46729.1 - 0.012 15.1 0.2 0.024 14.1 0.0 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KIY46729.1 - 0.029 14.8 0.0 0.098 13.1 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KIY46729.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 KIY46729.1 - 0.14 11.3 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein SNF5 PF04855.12 KIY46732.1 - 8.3e-72 241.8 0.5 1.1e-70 238.2 0.5 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 WD40 PF00400.32 KIY46733.1 - 2.9e-11 43.7 0.8 0.00066 20.4 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat DNA_pol_B_thumb PF14791.6 KIY46735.1 - 3.5e-14 52.7 0.1 8.9e-14 51.4 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KIY46735.1 - 2.7e-10 40.5 0.0 1.1e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KIY46735.1 - 2.7e-10 40.4 0.4 2.3e-09 37.5 0.4 2.3 1 1 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KIY46735.1 - 0.095 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain K_trans PF02705.16 KIY46736.1 - 5.6e-176 586.2 10.1 7.5e-176 585.8 10.1 1.1 1 0 0 1 1 1 1 K+ potassium transporter Gelsolin PF00626.22 KIY46737.1 - 3.5e-32 110.1 0.0 1.8e-16 59.8 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat CH PF00307.31 KIY46738.1 - 5.4e-46 155.3 0.0 1.1e-25 90.0 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KIY46738.1 - 8.7e-18 64.2 0.0 1.4e-16 60.4 0.0 2.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KIY46738.1 - 2.9e-12 46.3 0.1 7.2e-09 35.4 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain Spc7 PF08317.11 KIY46738.1 - 0.0071 15.3 6.0 0.0071 15.3 6.0 1.8 1 1 1 2 2 2 1 Spc7 kinetochore protein EF-hand_14 PF17959.1 KIY46738.1 - 0.026 14.9 1.3 0.59 10.5 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain SF-assemblin PF06705.11 KIY46738.1 - 0.026 13.9 3.6 0.061 12.7 3.6 1.6 1 0 0 1 1 1 0 SF-assemblin/beta giardin HMMR_N PF15905.5 KIY46738.1 - 0.058 12.9 5.2 0.2 11.1 5.1 1.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3153 PF11353.8 KIY46738.1 - 0.16 11.5 2.4 0.3 10.6 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Fib_alpha PF08702.10 KIY46738.1 - 0.42 10.8 4.3 0.19 11.9 0.4 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2205 PF10224.9 KIY46738.1 - 0.44 10.6 2.0 7.9 6.6 0.2 2.5 2 0 0 2 2 2 0 Short coiled-coil protein Baculo_PEP_C PF04513.12 KIY46738.1 - 0.45 10.5 4.7 0.54 10.3 0.7 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KIY46738.1 - 0.47 11.1 2.7 0.99 10.1 0.3 2.8 3 0 0 3 3 2 0 SlyX Exonuc_VII_L PF02601.15 KIY46738.1 - 1.4 8.4 4.5 1.9 8.0 4.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 KIY46738.1 - 8.8 5.7 10.7 2.7 7.4 7.2 1.9 2 1 0 2 2 2 0 Golgin subfamily A member 5 Cofilin_ADF PF00241.20 KIY46739.1 - 1.4e-43 147.5 0.9 1.6e-43 147.3 0.9 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH_14 PF17787.1 KIY46739.1 - 0.031 14.1 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 PH domain Adaptin_binding PF10199.9 KIY46740.1 - 0.00072 20.1 16.7 0.0015 19.1 13.6 2.7 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Mob1_phocein PF03637.17 KIY46741.1 - 9.3e-63 211.2 0.6 1.1e-62 211.0 0.6 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF2990 PF11693.8 KIY46741.1 - 0.12 12.6 0.1 0.69 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) POB3_N PF17292.2 KIY46742.1 - 1.1e-31 109.2 0.0 1.7e-27 95.7 0.0 2.5 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KIY46742.1 - 7.3e-27 93.1 0.0 1.8e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KIY46742.1 - 5.5e-24 84.4 0.2 3.5e-20 72.2 0.1 2.4 2 0 0 2 2 2 2 Histone chaperone Rttp106-like SRF-TF PF00319.18 KIY46743.1 - 4.1e-22 77.4 0.1 5.3e-22 77.0 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Asp PF00026.23 KIY46744.1 - 8.6e-43 146.9 15.9 1.7e-42 146.0 15.9 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY46744.1 - 9.5e-07 29.2 6.5 5.4e-05 23.5 0.5 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY46744.1 - 0.0023 18.5 6.6 0.044 14.4 2.2 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KIY46744.1 - 0.16 12.6 3.3 0.43 11.2 0.2 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease K_trans PF02705.16 KIY46745.1 - 6.4e-172 572.8 11.5 7.6e-172 572.5 11.5 1.0 1 0 0 1 1 1 1 K+ potassium transporter Methyltransf_11 PF08241.12 KIY46746.1 - 9.6e-08 32.6 0.0 1.1e-07 32.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY46746.1 - 2.5e-07 31.3 0.0 3.1e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY46746.1 - 0.00043 19.7 0.0 0.0005 19.5 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KIY46746.1 - 0.11 11.1 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase BTB PF00651.31 KIY46747.1 - 0.0067 16.7 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3452 PF11934.8 KIY46747.1 - 0.03 13.9 0.0 8.7 5.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) HMG_box_2 PF09011.10 KIY46748.1 - 0.15 12.7 0.7 5.1 7.8 0.0 2.2 2 0 0 2 2 2 0 HMG-box domain Ribonuc_red_lgC PF02867.15 KIY46749.1 - 5.7e-177 589.4 0.0 7.4e-177 589.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KIY46749.1 - 3.8e-25 87.7 0.1 9.2e-25 86.5 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KIY46749.1 - 1.1e-17 64.3 0.0 2.9e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain MGTL PF17059.5 KIY46750.1 - 0.57 10.1 7.6 1.4 8.8 7.6 1.7 1 0 0 1 1 1 0 MgtA leader peptide zf-C2H2 PF00096.26 KIY46751.1 - 1.5e-12 47.2 8.5 5.4e-06 26.6 1.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY46751.1 - 3.4e-09 36.7 13.9 2.1e-07 31.0 2.5 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY46751.1 - 8.5e-07 29.3 7.2 0.003 18.3 1.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIY46751.1 - 0.00031 21.3 0.4 0.071 13.7 0.0 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KIY46751.1 - 0.0083 16.3 0.8 1.3 9.1 0.1 2.0 1 1 1 2 2 2 2 Aberrant zinc-finger Ogr_Delta PF04606.12 KIY46751.1 - 0.023 14.7 0.0 1.4 9.0 0.0 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger RPAP2_Rtr1 PF04181.13 KIY46751.1 - 0.08 13.3 0.6 2 8.8 0.6 2.1 1 1 0 1 1 1 0 Rtr1/RPAP2 family F-box-like PF12937.7 KIY46753.1 - 4.6e-11 42.4 2.1 6.3e-10 38.8 0.1 2.6 2 1 0 2 2 2 1 F-box-like 8TM_micro PF17028.5 KIY46753.1 - 0.035 13.8 0.1 0.056 13.1 0.1 1.3 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain F-box PF00646.33 KIY46753.1 - 0.46 10.4 3.3 7.8 6.5 0.8 2.8 2 0 0 2 2 2 0 F-box domain Aldo_ket_red PF00248.21 KIY46754.1 - 8.4e-41 140.1 0.0 2e-32 112.6 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family Asp PF00026.23 KIY46755.1 - 1.6e-40 139.5 10.7 5.5e-40 137.7 10.7 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY46755.1 - 3.2e-06 27.5 4.4 3.4e-05 24.2 0.2 3.4 3 1 1 4 4 4 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY46755.1 - 0.0026 18.4 3.0 0.23 12.1 0.2 2.8 2 1 0 2 2 2 2 Aspartyl protease DUF1674 PF07896.12 KIY46758.1 - 5.6e-17 61.9 4.3 7.3e-17 61.6 4.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Sybindin PF04099.12 KIY46759.1 - 3e-18 66.1 0.0 6.4e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 Sybindin-like family zf-CCCH PF00642.24 KIY46760.1 - 3.3e-14 52.3 16.3 4.6e-07 29.6 3.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY46760.1 - 0.0024 18.5 0.6 1.6 9.4 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KIY46760.1 - 0.0065 16.5 3.3 0.0065 16.5 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 KIY46760.1 - 0.0087 15.9 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 KIY46760.1 - 0.013 15.7 4.4 0.33 11.2 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Alg14 PF08660.11 KIY46761.1 - 9.4e-56 188.5 0.0 1.1e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TPR_1 PF00515.28 KIY46762.1 - 6.4e-24 82.7 9.3 3.2e-05 23.6 0.1 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIY46762.1 - 3.1e-20 70.6 12.5 0.0003 20.7 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC8 PF04049.13 KIY46762.1 - 5e-17 62.3 0.2 5e-17 62.3 0.2 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KIY46762.1 - 3.8e-16 57.9 8.1 0.0001 22.2 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY46762.1 - 3.2e-11 43.7 7.4 0.0021 18.7 0.0 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY46762.1 - 1.8e-08 34.5 14.2 0.005 17.6 0.0 7.3 5 2 3 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY46762.1 - 2.2e-08 33.5 9.7 0.07 13.2 0.1 6.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 KIY46762.1 - 2.9e-08 33.3 1.5 0.0017 17.6 0.3 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY46762.1 - 4.8e-08 32.8 1.6 0.37 11.3 0.2 5.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY46762.1 - 4.9e-08 32.5 5.1 2.8e-05 23.7 0.8 3.9 3 1 1 4 4 4 2 TPR repeat TPR_19 PF14559.6 KIY46762.1 - 9.7e-07 29.2 3.9 0.43 11.1 0.0 6.0 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY46762.1 - 9.8e-06 25.6 8.3 0.057 13.6 0.3 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY46762.1 - 3.7e-05 23.9 20.5 0.021 15.1 0.7 5.9 5 1 1 6 6 5 2 Tetratricopeptide repeat FAT PF02259.23 KIY46762.1 - 0.0039 16.5 2.3 1 8.5 0.1 2.7 1 1 1 2 2 2 2 FAT domain ChAPs PF09295.10 KIY46762.1 - 0.01 14.9 0.2 0.24 10.3 0.0 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Sel1 PF08238.12 KIY46762.1 - 0.27 12.0 5.0 0.43 11.3 0.1 3.4 3 0 0 3 3 3 0 Sel1 repeat Docking PF08990.11 KIY46762.1 - 3.9 7.2 8.0 1.4 8.6 2.1 3.2 4 0 0 4 4 4 0 Erythronolide synthase docking TPR_6 PF13174.6 KIY46762.1 - 7.9 7.3 13.6 27 5.7 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF2398 PF09661.10 KIY46763.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) Mito_carr PF00153.27 KIY46764.1 - 4.8e-15 55.3 0.0 1.7e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein ECSCR PF15820.5 KIY46764.1 - 0.17 11.7 0.5 5.1 7.0 0.0 2.6 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator OSTbeta PF15048.6 KIY46764.1 - 0.37 10.9 1.5 0.41 10.8 0.1 1.7 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF3094 PF11293.8 KIY46764.1 - 5.9 6.7 6.0 6.4 6.6 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3094) SNF2_N PF00176.23 KIY46765.1 - 2e-43 148.5 0.1 6.5e-37 127.1 0.0 2.5 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY46765.1 - 9.9e-20 70.9 0.1 2.8e-19 69.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY46765.1 - 1.3e-08 35.0 0.0 4.8e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIY46765.1 - 9.4e-06 25.0 0.3 2.4e-05 23.7 0.3 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 KIY46765.1 - 0.0028 17.9 0.1 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF244 PF03112.14 KIY46765.1 - 0.09 12.6 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Las1 PF04031.13 KIY46766.1 - 1.1e-43 149.0 0.2 2.4e-43 147.9 0.1 1.6 2 0 0 2 2 2 1 Las1-like Voltage_CLC PF00654.20 KIY46768.1 - 3.1e-88 296.4 20.1 3.1e-88 296.4 20.1 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel DUF3128 PF11326.8 KIY46770.1 - 2.8e-24 85.3 1.3 3.8e-24 84.9 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Abhydrolase_3 PF07859.13 KIY46771.1 - 1.7e-30 106.5 0.0 2.3e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY46771.1 - 1.4e-08 34.0 0.0 2.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase P66_CC PF16563.5 KIY46771.1 - 0.1 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Glyco_hydro_71 PF03659.14 KIY46772.1 - 1.1e-106 356.8 12.6 1.1e-106 356.8 12.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 WSC PF01822.19 KIY46772.1 - 3.2e-25 88.1 35.9 1.9e-15 56.8 14.4 3.4 4 0 0 4 4 4 2 WSC domain CFIA_Pcf11 PF11526.8 KIY46772.1 - 6 7.4 8.1 1.5 9.3 0.6 2.7 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 zf-Paramyx-P PF13008.7 KIY46772.1 - 8.1 6.0 11.0 9.4 5.8 0.5 3.6 2 1 1 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein CX9C PF16860.5 KIY46773.1 - 0.0035 17.3 0.3 0.0065 16.4 0.3 1.5 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 KIY46773.1 - 0.019 15.2 0.8 0.065 13.5 0.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KIY46773.1 - 0.056 13.8 0.7 0.079 13.3 0.7 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 KIY46773.1 - 0.06 13.5 1.0 0.11 12.7 1.0 1.5 1 1 0 1 1 1 0 CHCH domain Asp PF00026.23 KIY46776.1 - 9.6e-65 219.1 6.8 1.2e-64 218.8 6.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY46776.1 - 7.8e-09 36.0 5.8 1.4e-05 25.4 0.3 3.0 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY46776.1 - 0.24 12.1 5.9 0.56 10.9 2.1 2.9 2 1 0 2 2 2 0 Aspartyl protease Sin3a_C PF16879.5 KIY46777.1 - 2.8e-71 240.6 0.6 1.2e-70 238.4 0.0 2.5 2 1 0 2 2 2 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KIY46777.1 - 9.4e-38 128.2 0.2 3.5e-37 126.4 0.2 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KIY46777.1 - 8.4e-29 99.5 2.5 6.3e-17 61.4 0.0 4.5 4 0 0 4 4 4 3 Paired amphipathic helix repeat QWRF PF04484.12 KIY46777.1 - 5.8 6.6 11.3 0.4 10.4 5.2 2.0 2 0 0 2 2 2 0 QWRF family DUF5340 PF17275.2 KIY46777.1 - 7.1 6.8 7.1 25 5.1 0.3 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5340) Pkinase PF00069.25 KIY46778.1 - 1.4e-73 247.5 0.0 1.7e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46778.1 - 9.3e-40 136.5 0.0 1.1e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY46778.1 - 3e-09 36.6 0.0 3.6e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FHA PF00498.26 KIY46778.1 - 2.4e-08 34.2 0.0 4.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 KIY46778.1 - 4.6e-07 29.4 0.1 7.3e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY46778.1 - 2.1e-05 23.6 0.0 2.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIY46778.1 - 0.0023 17.5 0.8 0.0074 15.9 0.8 1.7 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KIY46778.1 - 0.0076 16.2 0.0 0.14 12.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY46778.1 - 0.014 14.2 0.0 0.036 12.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase RBFA PF02033.18 KIY46779.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosome-binding factor A API5 PF05918.11 KIY46780.1 - 7.3e-22 77.9 2.3 7.3e-22 77.9 2.3 1.8 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 KIY46780.1 - 9.1e-06 26.0 3.8 0.0004 20.7 0.4 4.3 4 2 1 5 5 5 1 HEAT repeats Tn7_Tnp_TnsA_C PF08721.11 KIY46780.1 - 0.15 12.8 0.4 2.3 8.9 0.1 2.8 2 0 0 2 2 2 0 TnsA endonuclease C terminal Cnd1 PF12717.7 KIY46780.1 - 0.78 9.8 4.0 1.1 9.3 0.8 2.3 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Cytochrom_B561 PF03188.16 KIY46781.1 - 4.5e-14 52.8 6.0 7.3e-14 52.1 6.0 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 KIY46781.1 - 1.5e-13 50.8 0.4 8.2e-13 48.4 0.4 2.1 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KIY46781.1 - 5.5e-05 23.4 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 KIY46781.1 - 0.0024 18.0 0.6 0.4 10.8 0.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF4079) PMP22_Claudin PF00822.20 KIY46781.1 - 0.056 13.3 0.1 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family FUSC_2 PF13515.6 KIY46782.1 - 9.7e-21 74.2 7.5 9.7e-21 74.2 7.5 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KIY46782.1 - 1.7e-08 33.7 4.0 1.7e-08 33.7 4.0 1.7 2 0 0 2 2 2 1 Aluminium activated malate transporter ArAE_2 PF10334.9 KIY46782.1 - 4.2e-08 33.3 0.2 1.2e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 KIY46782.1 - 4.6e-08 32.1 6.7 4.6e-08 32.1 6.7 3.3 2 2 1 3 3 3 1 Fusaric acid resistance protein family FUSC-like PF12805.7 KIY46782.1 - 0.0013 17.9 4.0 0.0022 17.1 0.4 2.4 2 0 0 2 2 2 1 FUSC-like inner membrane protein yccS ArAE_1 PF06081.11 KIY46782.1 - 0.0092 16.1 0.4 0.0092 16.1 0.4 2.7 3 0 0 3 3 3 1 Aromatic acid exporter family member 1 Zn_clus PF00172.18 KIY46783.1 - 7.2e-05 22.8 5.9 7.2e-05 22.8 5.9 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPC22 PF04573.12 KIY46784.1 - 1.1e-49 168.3 0.1 1.2e-49 168.1 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit S-methyl_trans PF02574.16 KIY46785.1 - 4.6e-48 164.4 0.0 7e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase PHD PF00628.29 KIY46786.1 - 2.5e-09 36.9 5.7 3.9e-09 36.2 5.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIY46786.1 - 0.00034 20.1 2.3 0.00059 19.3 2.3 1.3 1 0 0 1 1 1 1 PHD-finger LSM PF01423.22 KIY46787.1 - 3.9e-14 52.1 0.2 5.1e-14 51.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KIY46787.1 - 0.015 15.4 0.1 0.02 15.0 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 KIY46787.1 - 0.033 14.3 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain GLTSCR1 PF15249.6 KIY46788.1 - 5.7e-27 94.1 0.3 8.7e-27 93.5 0.3 1.3 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein DUF3510 PF12022.8 KIY46789.1 - 1.2e-29 103.2 0.0 3.6e-29 101.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KIY46789.1 - 3.5e-26 91.9 1.6 8.4e-26 90.6 1.6 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 PEPcase PF00311.17 KIY46789.1 - 0.0027 15.9 0.5 0.26 9.3 0.0 2.1 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase DFF-C PF09033.10 KIY46789.1 - 0.0037 17.2 0.5 0.015 15.2 0.5 2.0 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain Vps51 PF08700.11 KIY46789.1 - 0.073 13.1 0.4 0.23 11.6 0.4 1.9 1 1 0 1 1 1 0 Vps51/Vps67 Arm PF00514.23 KIY46790.1 - 7.4e-10 38.5 13.3 7.1e-06 25.9 0.0 7.2 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 KIY46790.1 - 1.2e-05 25.2 4.5 0.0098 15.8 0.0 3.5 3 1 1 4 4 4 2 Domain of unknown function (DUF3361) HEAT_2 PF13646.6 KIY46790.1 - 7e-05 23.1 9.0 0.58 10.6 0.0 6.4 4 2 3 7 7 7 1 HEAT repeats Cnd1 PF12717.7 KIY46790.1 - 0.0011 19.1 2.2 1.5 8.9 0.0 3.6 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIY46790.1 - 0.0017 18.8 2.6 9.6 6.8 0.0 5.8 5 0 0 5 5 5 1 HEAT-like repeat Atx10homo_assoc PF09759.9 KIY46790.1 - 0.0022 18.0 1.2 15 5.7 0.0 5.5 6 0 0 6 6 6 1 Spinocerebellar ataxia type 10 protein domain Phage_holin_3_1 PF05106.12 KIY46790.1 - 0.0032 17.9 0.0 0.033 14.6 0.0 2.7 2 0 0 2 2 2 1 Phage holin family (Lysis protein S) Adaptin_N PF01602.20 KIY46790.1 - 0.024 13.2 4.9 1.3 7.5 0.2 3.4 3 1 1 4 4 4 0 Adaptin N terminal region Adenylate_cycl PF01295.18 KIY46790.1 - 0.14 10.8 0.2 0.22 10.1 0.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I HEAT PF02985.22 KIY46790.1 - 5.2 7.6 20.5 62 4.2 0.0 8.3 10 0 0 10 10 10 0 HEAT repeat Zn_clus PF00172.18 KIY46791.1 - 2.6e-07 30.7 15.0 4.3e-07 30.0 15.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY46791.1 - 1.1e-05 24.6 0.1 1.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain VCX_VCY PF15231.6 KIY46791.1 - 0.017 15.8 0.9 0.038 14.7 0.9 1.6 1 0 0 1 1 1 0 Variable charge X/Y family SPA PF08616.10 KIY46793.1 - 2.3e-34 117.8 0.0 4.3e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KIY46793.1 - 1.9e-15 57.5 2.0 3.4e-12 47.0 0.2 3.1 3 0 0 3 3 3 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KIY46793.1 - 0.00021 20.1 0.0 0.54 8.9 0.0 3.4 3 0 0 3 3 3 2 Transport protein Avl9 SPX PF03105.19 KIY46793.1 - 0.0022 18.0 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 SPX domain DUF2347 PF09804.9 KIY46793.1 - 0.013 15.1 0.0 0.33 10.5 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) ATF7IP_BD PF16788.5 KIY46793.1 - 0.13 12.3 3.2 0.23 11.5 3.2 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain HsbA PF12296.8 KIY46794.1 - 0.15 12.5 9.4 0.06 13.8 6.5 1.7 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Sugar_tr PF00083.24 KIY46795.1 - 4.2e-128 428.0 24.8 6.9e-128 427.3 24.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY46795.1 - 6e-18 64.9 42.8 1.7e-17 63.4 35.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY46795.1 - 1.2e-06 27.7 7.4 0.00036 19.5 7.4 3.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KIY46796.1 - 1.6e-13 50.3 27.6 1.6e-13 50.3 27.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KIY46796.1 - 1.6e-11 44.2 3.2 5.4e-11 42.4 1.8 2.1 1 1 0 2 2 2 1 Nodulin-like FAD_binding_3 PF01494.19 KIY46797.1 - 9.2e-72 242.2 0.0 1.3e-71 241.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY46797.1 - 2e-06 27.2 0.4 0.00025 20.4 0.0 3.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY46797.1 - 7.4e-06 26.1 0.1 2.1e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY46797.1 - 0.00011 22.6 0.1 0.0016 19.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY46797.1 - 0.00029 20.0 0.6 0.00082 18.6 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIY46797.1 - 0.00037 19.3 0.1 0.00066 18.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KIY46797.1 - 0.00076 18.4 0.4 0.0023 16.9 0.1 1.8 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 KIY46797.1 - 0.0016 18.1 1.3 0.0043 16.7 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIY46797.1 - 0.003 16.9 0.0 0.0061 15.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIY46797.1 - 0.0033 16.7 0.1 0.0058 15.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY46797.1 - 0.019 14.0 2.3 0.02 13.9 0.3 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 KIY46797.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 KIY46797.1 - 0.045 13.3 0.1 0.095 12.3 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AhpC-TSA PF00578.21 KIY46797.1 - 0.052 13.5 0.0 1.7 8.5 0.0 2.3 1 1 1 2 2 2 0 AhpC/TSA family NAD_binding_9 PF13454.6 KIY46797.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KIY46797.1 - 0.14 12.4 0.1 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 KIY46800.1 - 1.1e-68 232.0 0.0 2.1e-68 231.2 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIY46800.1 - 5.6e-05 23.3 0.0 0.00016 21.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY46800.1 - 0.00011 21.6 0.0 0.004 16.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY46800.1 - 0.001 19.6 0.0 0.0027 18.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY46800.1 - 0.0013 17.5 0.1 0.0055 15.5 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KIY46800.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 KIY46800.1 - 0.0033 17.1 1.2 0.0067 16.0 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY46800.1 - 0.0051 16.0 0.1 0.0089 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY46800.1 - 0.0077 15.5 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY46800.1 - 0.012 14.8 1.0 0.022 14.0 0.0 1.9 3 0 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.12 KIY46800.1 - 0.08 12.0 0.4 0.37 9.8 0.2 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Glyco_hydro_3_C PF01915.22 KIY46801.1 - 3.5e-47 161.0 0.0 7.2e-47 160.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY46801.1 - 1.5e-22 80.4 0.0 1e-21 77.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY46801.1 - 2.2e-19 69.3 0.0 3.9e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain SE PF08491.10 KIY46802.1 - 1.4e-73 247.3 0.0 2.8e-73 246.4 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KIY46802.1 - 2.1e-09 37.4 0.9 1.2e-07 31.7 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIY46802.1 - 8.1e-09 35.2 0.0 1.2e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIY46802.1 - 0.00014 21.2 0.0 0.0004 19.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KIY46802.1 - 0.002 18.3 0.0 0.0072 16.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY46802.1 - 0.0048 16.9 0.1 0.0085 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIY46802.1 - 0.0092 15.1 0.2 0.36 9.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KIY46802.1 - 0.016 14.1 0.1 0.19 10.6 0.1 2.2 1 1 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 KIY46802.1 - 0.04 14.2 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 KIY46802.1 - 0.049 12.7 0.0 0.47 9.4 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY46802.1 - 0.05 12.8 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KIY46802.1 - 0.075 12.4 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 GMC oxidoreductase GIDA PF01134.22 KIY46802.1 - 0.1 11.7 0.0 4.3 6.3 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.18 KIY46803.1 - 1.3e-19 70.3 0.4 1.9e-19 69.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KIY46804.1 - 8.4e-109 364.4 23.6 9.9e-109 364.2 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY46804.1 - 5.4e-27 94.6 22.2 5.4e-27 94.6 22.2 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Holin_2-3 PF13272.6 KIY46804.1 - 0.033 14.5 0.4 2 8.8 0.1 2.7 2 0 0 2 2 2 0 Putative 2/3 transmembrane domain holin Alpha-amylase PF00128.24 KIY46805.1 - 1.4e-17 64.3 0.0 1.6e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIY46805.1 - 7e-07 29.6 0.1 1.7e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_70 PF02324.16 KIY46805.1 - 0.07 11.3 0.0 0.12 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Pyrophosphatase PF00719.19 KIY46806.1 - 6.1e-61 204.9 0.4 7.7e-61 204.6 0.4 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dimer_Tnp_hAT PF05699.14 KIY46808.1 - 6.5e-07 29.1 0.1 8.1e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Methyltransf_23 PF13489.6 KIY46812.1 - 1e-10 41.7 0.0 2.9e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY46812.1 - 5.8e-08 33.3 0.0 1.9e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY46812.1 - 7.3e-08 33.1 0.0 2.7e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY46812.1 - 4.2e-05 24.1 0.0 0.00047 20.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY46812.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY46812.1 - 0.0019 17.8 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain SnoaL_4 PF13577.6 KIY46814.1 - 1.5e-11 44.5 0.1 2.9e-11 43.6 0.1 1.5 2 0 0 2 2 2 1 SnoaL-like domain RRM_1 PF00076.22 KIY46816.1 - 5.8e-13 48.5 0.0 7.3e-12 44.9 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KIY46817.1 - 8.6e-18 63.9 0.0 1.3e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY46817.1 - 2e-05 24.6 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIY46817.1 - 3.7e-05 23.6 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KIY46817.1 - 0.0022 17.6 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY46817.1 - 0.0045 16.8 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KIY46817.1 - 0.027 14.6 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif GCV_T PF01571.21 KIY46819.1 - 2.5e-81 272.9 0.0 2.9e-81 272.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KIY46819.1 - 1.7e-22 79.1 0.0 3.7e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SPRY PF00622.28 KIY46820.1 - 0.0027 17.8 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Epimerase PF01370.21 KIY46821.1 - 4e-16 59.2 0.0 6.4e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY46821.1 - 2e-12 46.7 0.0 3.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIY46821.1 - 5.5e-10 39.4 0.6 9.3e-10 38.7 0.6 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIY46821.1 - 2.2e-07 30.6 0.3 9.2e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIY46821.1 - 2.1e-06 27.1 0.0 3e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KIY46821.1 - 2.9e-06 27.0 0.2 4.4e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIY46821.1 - 0.0033 16.9 1.2 0.017 14.6 1.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY46821.1 - 0.018 15.0 0.3 0.16 11.8 0.3 2.1 1 1 0 1 1 1 0 KR domain FAD_binding_3 PF01494.19 KIY46823.1 - 0.00027 20.3 0.0 0.00027 20.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain IL5 PF02025.15 KIY46824.1 - 0.013 15.8 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Interleukin 5 DUF2207 PF09972.9 KIY46824.1 - 0.02 13.7 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1198 PF06711.11 KIY46824.1 - 0.024 14.7 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) DUF5576 PF17739.1 KIY46826.1 - 0.058 13.5 1.0 0.12 12.5 0.6 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5576) HrpB2 PF09487.10 KIY46826.1 - 0.072 13.5 0.4 0.11 12.9 0.4 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) FUSC PF04632.12 KIY46826.1 - 0.47 8.9 2.3 0.54 8.7 2.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Treacle PF03546.14 KIY46826.1 - 4.2 6.1 10.0 11 4.7 10.0 1.6 1 1 0 1 1 1 0 Treacher Collins syndrome protein Treacle Methyltransf_15 PF09445.10 KIY46827.1 - 9.6e-40 135.8 0.0 2.2e-28 98.9 0.0 2.1 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KIY46827.1 - 1.1e-07 32.5 0.0 2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KIY46827.1 - 4.4e-07 29.8 0.1 2.4e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_31 PF13847.6 KIY46827.1 - 8.6e-07 28.9 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KIY46827.1 - 3.2e-06 26.9 0.0 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KIY46827.1 - 2.3e-05 25.0 0.0 4.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KIY46827.1 - 0.00079 19.2 0.0 0.0049 16.6 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 KIY46827.1 - 0.00098 18.6 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 KIY46827.1 - 0.0017 17.4 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.7 KIY46827.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY46827.1 - 0.006 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Peripla_BP_2 PF01497.18 KIY46827.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Ubie_methyltran PF01209.18 KIY46827.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TRM PF02005.16 KIY46827.1 - 0.072 12.2 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_12 PF08242.12 KIY46827.1 - 0.08 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KIY46827.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1899 PF08953.11 KIY46828.1 - 3.8e-27 93.9 0.1 6.7e-27 93.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KIY46828.1 - 3.5e-18 65.2 0.4 9.4e-18 63.8 0.4 1.8 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KIY46828.1 - 3.2e-15 56.3 4.6 0.00017 22.3 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY46828.1 - 6.6e-06 26.3 0.0 0.1 12.9 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HALZ PF02183.18 KIY46828.1 - 0.0013 18.9 0.1 0.0021 18.2 0.1 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper Nup160 PF11715.8 KIY46828.1 - 0.018 13.7 0.0 1.1 7.9 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 TMF_DNA_bd PF12329.8 KIY46828.1 - 0.058 13.4 0.4 0.091 12.8 0.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 KIY46828.1 - 0.066 13.4 0.9 0.1 12.8 0.9 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 LPP PF04728.13 KIY46828.1 - 0.073 13.5 1.1 0.16 12.4 1.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper bZIP_1 PF00170.21 KIY46828.1 - 0.086 13.0 0.4 0.086 13.0 0.4 1.7 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 KIY46828.1 - 0.091 12.5 2.0 0.16 11.8 2.0 1.3 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 KIY46828.1 - 0.11 13.0 1.3 0.18 12.3 1.3 1.2 1 0 0 1 1 1 0 Cell division protein ZapB Fungal_TACC PF12709.7 KIY46828.1 - 0.23 11.9 0.1 0.43 11.0 0.1 1.3 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins SARG PF15385.6 KIY46828.1 - 0.58 9.3 5.1 0.8 8.9 5.1 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein RCC1 PF00415.18 KIY46829.1 - 4.2e-41 139.4 9.8 3.1e-11 43.7 0.0 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY46829.1 - 1.1e-17 63.3 19.9 1.1e-07 31.4 0.4 4.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KIY46829.1 - 1e-12 47.7 9.9 2.9e-12 46.3 9.9 1.8 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 KIY46829.1 - 1.1 9.6 13.1 1.7 9.0 10.4 2.4 2 0 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 KIY46829.1 - 1.2 9.2 14.8 0.028 14.3 7.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_9 PF13901.6 KIY46829.1 - 2.6 8.0 5.4 4.3 7.3 5.4 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-HC5HC2H_2 PF13832.6 KIY46829.1 - 3.6 7.8 6.1 0.48 10.6 1.2 2.0 3 0 0 3 3 3 0 PHD-zinc-finger like domain Ribosomal_60s PF00428.19 KIY46829.1 - 5.7 7.6 6.3 13 6.5 6.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nup35_RRM PF05172.13 KIY46830.1 - 7.1e-06 25.9 0.0 9.7e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KIY46830.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FAD_binding_3 PF01494.19 KIY46831.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain SQS_PSY PF00494.19 KIY46832.1 - 2.4e-35 122.3 0.0 4.1e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DHHC PF01529.20 KIY46832.1 - 0.065 13.3 0.1 0.99 9.5 0.0 2.6 3 0 0 3 3 3 0 DHHC palmitoyltransferase PspB PF06667.12 KIY46832.1 - 0.16 12.1 1.1 0.48 10.5 1.1 1.8 1 0 0 1 1 1 0 Phage shock protein B Aminotran_5 PF00266.19 KIY46833.1 - 2.2e-39 135.5 0.0 6e-39 134.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Arylsulfotran_2 PF14269.6 KIY46834.1 - 7.7e-40 137.1 0.0 1e-39 136.7 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY46834.1 - 2.1e-12 46.7 0.0 4.7e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) F-box-like PF12937.7 KIY46837.1 - 6.6e-09 35.5 0.8 1.7e-08 34.2 0.8 1.7 1 0 0 1 1 1 1 F-box-like CIMR PF00878.18 KIY46838.1 - 0.082 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat ABC_tran PF00005.27 KIY46839.1 - 8.2e-46 155.9 0.0 1.3e-21 77.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KIY46839.1 - 1.3e-19 70.0 4.7 1.3e-19 70.0 4.7 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KIY46839.1 - 2.2e-15 57.2 5.7 0.00011 22.2 0.1 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY46839.1 - 3e-09 37.5 0.1 0.0007 20.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIY46839.1 - 2.6e-08 33.5 0.1 0.0031 17.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KIY46839.1 - 3.5e-08 33.2 6.5 0.084 12.3 0.3 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KIY46839.1 - 9.2e-07 28.9 0.1 0.059 13.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 KIY46839.1 - 1.6e-06 28.8 9.0 0.012 16.2 0.0 4.0 5 0 0 5 5 3 2 AAA domain Dynamin_N PF00350.23 KIY46839.1 - 5.6e-05 23.3 2.8 0.11 12.5 0.0 4.1 2 2 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 KIY46839.1 - 7.3e-05 22.7 0.1 0.1 12.5 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 KIY46839.1 - 0.00013 22.0 0.3 0.42 10.7 0.0 3.6 4 0 0 4 4 3 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY46839.1 - 0.00015 22.3 0.0 0.42 11.2 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KIY46839.1 - 0.00027 21.2 0.0 0.48 10.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY46839.1 - 0.00082 19.6 0.0 0.85 9.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KIY46839.1 - 0.0012 18.3 0.0 0.58 9.5 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 KIY46839.1 - 0.0012 19.2 0.0 2.5 8.5 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KIY46839.1 - 0.0013 18.5 0.1 2.3 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 KIY46839.1 - 0.0014 18.6 0.1 0.54 10.2 0.0 3.2 3 0 0 3 3 3 1 NTPase AAA_30 PF13604.6 KIY46839.1 - 0.0015 18.3 0.3 0.69 9.6 0.0 3.5 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 KIY46839.1 - 0.0018 18.4 5.9 0.34 11.0 0.0 3.9 5 1 0 5 5 3 2 Helicase HerA, central domain AAA_28 PF13521.6 KIY46839.1 - 0.0023 18.2 0.0 0.3 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KIY46839.1 - 0.0028 17.7 0.1 5.7 7.0 0.0 4.4 4 2 3 7 7 5 0 AAA domain NB-ARC PF00931.22 KIY46839.1 - 0.0032 16.7 0.0 0.63 9.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 KIY46839.1 - 0.0049 16.5 0.2 17 4.9 0.0 3.6 4 0 0 4 4 3 0 AAA domain G-alpha PF00503.20 KIY46839.1 - 0.007 15.6 0.1 1.1 8.4 0.0 2.7 2 1 0 2 2 2 1 G-protein alpha subunit AAA_27 PF13514.6 KIY46839.1 - 0.0092 15.6 1.9 0.76 9.3 0.0 3.3 5 0 0 5 5 4 1 AAA domain Roc PF08477.13 KIY46839.1 - 0.011 15.9 0.1 5.7 7.2 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 KIY46839.1 - 0.012 14.3 0.8 2.9 6.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 KIY46839.1 - 0.017 15.5 0.0 18 5.7 0.0 3.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 KIY46839.1 - 0.019 14.7 0.4 5.3 6.7 0.0 3.4 4 1 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family MukB PF04310.12 KIY46839.1 - 0.026 14.3 0.2 2 8.1 0.0 3.3 3 1 0 3 3 3 0 MukB N-terminal AAA_15 PF13175.6 KIY46839.1 - 0.028 14.1 19.1 0.86 9.2 0.1 5.3 2 2 2 4 4 4 0 AAA ATPase domain ATP-synt_ab PF00006.25 KIY46839.1 - 0.031 13.9 0.0 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 KIY46839.1 - 0.032 13.5 0.2 1.7 7.9 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin TsaE PF02367.17 KIY46839.1 - 0.033 14.2 0.1 13 5.8 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KIY46839.1 - 0.035 13.9 0.2 6.4 6.5 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 KIY46839.1 - 0.036 14.5 0.0 13 6.2 0.0 3.8 4 0 0 4 4 2 0 AAA domain Arf PF00025.21 KIY46839.1 - 0.047 13.2 0.7 0.58 9.6 0.0 2.9 4 0 0 4 4 3 0 ADP-ribosylation factor family DUF5424 PF17462.2 KIY46839.1 - 0.06 13.3 0.6 0.15 12.0 0.4 1.8 2 0 0 2 2 1 0 Family of unknown function (DUF5424) AAA_5 PF07728.14 KIY46839.1 - 0.077 13.0 0.1 9.4 6.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 KIY46839.1 - 0.088 12.2 1.1 6.1 6.2 0.0 3.0 3 0 0 3 3 3 0 Poxvirus A32 protein DUF3584 PF12128.8 KIY46839.1 - 0.1 10.1 1.9 0.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Viral_helicase1 PF01443.18 KIY46839.1 - 0.11 12.2 0.0 18 5.0 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase LAGLIDADG_WhiA PF14527.6 KIY46839.1 - 0.23 11.6 1.1 2.3 8.3 0.1 2.5 1 1 1 2 2 2 0 WhiA LAGLIDADG-like domain ABC_tran_CTD PF16326.5 KIY46839.1 - 0.64 10.3 8.4 0.097 12.9 1.4 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Thymidylate_kin PF02223.17 KIY46839.1 - 0.65 9.7 7.0 9.6 5.8 0.0 4.1 5 0 0 5 5 5 0 Thymidylate kinase Pkinase PF00069.25 KIY46840.1 - 2.2e-15 56.8 0.0 2.7e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY46840.1 - 3.5e-06 26.5 0.0 4.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_31 PF13847.6 KIY46841.1 - 3.8e-24 85.2 0.0 5.2e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY46841.1 - 3.1e-18 66.2 0.3 7.3e-18 65.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY46841.1 - 1.1e-16 61.3 0.1 3.3e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY46841.1 - 1.7e-15 57.0 0.0 3.7e-15 55.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIY46841.1 - 7.7e-12 45.4 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY46841.1 - 2e-07 31.6 0.0 3.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY46841.1 - 5.9e-07 29.5 0.0 1.4e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KIY46841.1 - 3.3e-06 26.7 0.0 5.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 KIY46841.1 - 1.1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 KIY46841.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KIY46841.1 - 0.0024 17.9 0.4 0.0032 17.5 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 KIY46841.1 - 0.006 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.26 KIY46841.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FtsJ PF01728.19 KIY46841.1 - 0.035 14.2 0.0 0.071 13.2 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 KIY46841.1 - 0.045 13.6 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase bZIP_1 PF00170.21 KIY46842.1 - 0.33 11.1 5.7 0.55 10.4 5.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor adh_short_C2 PF13561.6 KIY46843.1 - 7.7e-53 179.4 1.5 1.1e-52 179.0 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY46843.1 - 4.3e-50 169.9 2.9 5.4e-50 169.6 2.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY46843.1 - 6.5e-09 35.9 0.8 8.6e-09 35.6 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY46843.1 - 0.0068 15.9 1.8 0.029 13.8 1.8 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 KIY46843.1 - 0.02 14.8 0.9 0.4 10.6 0.1 2.3 2 1 0 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KIY46843.1 - 0.11 12.4 1.3 0.11 12.3 0.4 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.7 KIY46844.1 - 0.00073 20.2 0.0 0.0015 19.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.20 KIY46845.1 - 1.6e-24 86.2 0.0 2.6e-24 85.6 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIY46845.1 - 0.00014 22.1 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIY46845.1 - 0.052 13.1 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF1924 PF09086.11 KIY46847.1 - 0.0028 18.0 0.3 0.0063 16.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1924) ATP-synt_Eps PF04627.13 KIY46849.1 - 2.3e-19 69.1 0.7 2.9e-19 68.8 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PikAIV_N PF18605.1 KIY46849.1 - 0.11 12.1 1.5 0.17 11.5 1.5 1.3 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Arrestin_C PF02752.22 KIY46850.1 - 8.6e-09 36.0 0.0 2.5e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIY46850.1 - 3.1e-05 24.1 0.0 7.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KIY46850.1 - 9.8e-05 22.1 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 Arrestin_N terminal like Glyco_hydro_88 PF07470.13 KIY46851.1 - 1e-84 284.6 0.1 1.2e-84 284.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Abhydrolase_6 PF12697.7 KIY46852.1 - 1.4e-07 32.4 5.2 2.5e-06 28.3 3.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY46852.1 - 0.0034 17.1 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HSF_DNA-bind PF00447.17 KIY46854.1 - 1.9e-29 102.1 0.4 3.2e-29 101.4 0.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding AAA_11 PF13086.6 KIY46854.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain DUF382 PF04037.13 KIY46855.1 - 8.3e-59 197.3 0.2 8.3e-59 197.3 0.2 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 KIY46855.1 - 1.6e-17 63.1 4.6 3.5e-17 62.0 4.6 1.6 1 0 0 1 1 1 1 PSP ATG16 PF08614.11 KIY46857.1 - 3.1e-06 27.6 14.9 0.0031 17.8 1.1 2.5 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Spc29 PF17082.5 KIY46857.1 - 1.4e-05 25.0 9.5 0.0091 15.9 1.5 2.3 2 0 0 2 2 2 2 Spindle Pole Component 29 KELK PF15796.5 KIY46857.1 - 3.7e-05 24.1 17.4 0.0016 18.8 7.8 3.5 3 0 0 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase SHE3 PF17078.5 KIY46857.1 - 0.00042 20.1 17.8 0.00064 19.5 4.9 2.3 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 DASH_Dad2 PF08654.10 KIY46857.1 - 0.0033 17.8 4.8 0.041 14.3 0.3 2.4 2 0 0 2 2 2 1 DASH complex subunit Dad2 EzrA PF06160.12 KIY46857.1 - 0.012 13.9 17.1 0.13 10.4 5.0 2.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF641 PF04859.12 KIY46857.1 - 0.013 15.8 9.7 0.096 13.0 0.1 3.0 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) MSA-2c PF12238.8 KIY46857.1 - 0.015 15.4 4.0 0.17 11.8 0.6 2.6 2 0 0 2 2 2 0 Merozoite surface antigen 2c GAS PF13851.6 KIY46857.1 - 0.022 14.1 20.1 0.14 11.5 7.8 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 KIY46857.1 - 0.026 13.8 7.8 0.26 10.5 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 KIY46857.1 - 0.028 15.0 8.9 0.95 10.1 0.7 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KIY46857.1 - 0.054 13.5 4.7 1.1 9.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 KIY46857.1 - 0.074 12.9 12.6 0.28 11.0 3.1 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 ADIP PF11559.8 KIY46857.1 - 0.14 12.2 14.6 1.6 8.8 1.0 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 KIY46857.1 - 0.19 11.5 13.3 1.2 8.9 2.9 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Fmp27_WPPW PF10359.9 KIY46857.1 - 0.36 9.6 17.6 0.53 9.1 4.6 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Tropomyosin_1 PF12718.7 KIY46857.1 - 0.63 10.2 20.1 0.039 14.1 4.6 2.5 2 0 0 2 2 2 0 Tropomyosin like Cob_adeno_trans PF01923.18 KIY46857.1 - 0.75 9.9 3.6 10 6.3 0.5 2.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase TMF_TATA_bd PF12325.8 KIY46857.1 - 0.79 10.0 18.2 0.99 9.6 5.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 KIY46857.1 - 0.84 10.0 13.4 3.5 8.0 3.2 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 KIY46857.1 - 0.94 9.5 15.4 7.3 6.7 2.9 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4250 PF14056.6 KIY46857.1 - 1.2 9.1 10.9 13 5.8 0.0 3.9 4 0 0 4 4 3 0 Domain of unknown function (DUF4250) Fez1 PF06818.15 KIY46857.1 - 1.3 9.4 20.1 2.6 8.4 6.6 2.2 2 0 0 2 2 2 0 Fez1 Exonuc_VII_L PF02601.15 KIY46857.1 - 1.4 8.5 13.0 1.7 8.2 1.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit YabA PF06156.13 KIY46857.1 - 1.4 9.6 13.2 4.4 8.0 3.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Holin_BhlA PF10960.8 KIY46857.1 - 1.4 8.9 6.5 4.1 7.4 0.7 2.7 2 1 0 2 2 2 0 BhlA holin family ERM PF00769.19 KIY46857.1 - 1.5 8.5 21.9 0.83 9.4 6.1 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Ax_dynein_light PF10211.9 KIY46857.1 - 1.6 8.7 17.8 2.1 8.2 3.8 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4611 PF15387.6 KIY46857.1 - 1.7 8.9 9.5 2.6 8.3 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Fib_alpha PF08702.10 KIY46857.1 - 1.8 8.7 8.4 1.6 9.0 1.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Lebercilin PF15619.6 KIY46857.1 - 1.8 8.1 21.9 2 8.0 7.7 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Taxilin PF09728.9 KIY46857.1 - 1.9 7.6 21.1 0.088 12.0 6.1 2.2 2 0 0 2 2 2 0 Myosin-like coiled-coil protein APG6_N PF17675.1 KIY46857.1 - 2.3 8.7 31.6 3.7 8.1 14.6 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF1117 PF06547.12 KIY46857.1 - 2.4 8.8 8.5 2 9.0 0.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1117) UPF0242 PF06785.11 KIY46857.1 - 2.4 8.2 18.3 5.4 7.1 5.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 KIY46857.1 - 2.5 7.5 17.6 4.3 6.7 4.0 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 Vps5 PF09325.10 KIY46857.1 - 3.6 7.1 16.6 1.1 8.8 3.8 2.2 2 0 0 2 2 2 0 Vps5 C terminal like DUF4407 PF14362.6 KIY46857.1 - 3.7 6.8 10.5 3.6 6.9 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 KIY46857.1 - 3.9 7.5 7.4 2.9 7.9 1.2 2.3 2 0 0 2 2 2 0 Laminin Domain II CENP-H PF05837.12 KIY46857.1 - 4.1 7.9 14.6 12 6.4 4.5 2.8 3 0 0 3 3 2 0 Centromere protein H (CENP-H) Spc7 PF08317.11 KIY46857.1 - 4.6 6.0 21.6 4.7 6.0 4.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.14 KIY46857.1 - 4.9 7.5 15.1 5 7.5 2.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Nsp1_C PF05064.13 KIY46857.1 - 5.2 6.9 7.9 2.8 7.8 0.7 3.2 2 1 1 3 3 3 0 Nsp1-like C-terminal region KLRAQ PF10205.9 KIY46857.1 - 5.3 7.4 13.9 2.3 8.5 3.2 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4140 PF13600.6 KIY46857.1 - 6.7 7.2 8.2 20 5.7 0.2 2.9 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF745 PF05335.13 KIY46857.1 - 8.5 6.1 9.3 1.7 8.3 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DASH_Dam1 PF08653.10 KIY46858.1 - 1.7e-19 69.3 0.5 2.1e-19 69.0 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dam1 PAP_assoc PF03828.19 KIY46859.1 - 3.6e-16 59.1 0.0 6.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIY46859.1 - 6e-08 32.9 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain FAD_binding_3 PF01494.19 KIY46860.1 - 3.8e-15 56.0 0.1 3e-14 53.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY46860.1 - 7.3e-05 22.9 0.9 0.00017 21.7 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY46860.1 - 0.00057 19.9 0.7 0.045 13.8 0.2 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KIY46860.1 - 0.00082 19.0 3.0 0.0018 18.0 3.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 KIY46860.1 - 0.0055 15.8 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 KIY46860.1 - 0.022 13.7 3.0 0.022 13.7 0.5 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 KIY46860.1 - 0.043 13.0 1.6 0.13 11.5 1.4 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KIY46860.1 - 0.089 12.0 1.4 0.13 11.5 0.5 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY46860.1 - 0.19 12.3 1.1 0.43 11.2 1.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY46860.1 - 0.33 9.6 2.9 0.52 8.9 2.9 1.3 1 0 0 1 1 1 0 HI0933-like protein BTB PF00651.31 KIY46861.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Fst_toxin PF13955.6 KIY46863.1 - 0.24 11.4 2.8 0.53 10.3 2.8 1.5 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system IMUP PF15761.5 KIY46863.1 - 2.1 9.1 16.1 5 7.9 6.0 3.1 3 0 0 3 3 3 0 Immortalisation up-regulated protein EphA2_TM PF14575.6 KIY46867.1 - 0.004 18.0 0.1 0.0055 17.6 0.1 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 KIY46867.1 - 0.0094 14.7 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E ECSCR PF15820.5 KIY46867.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator MFS_1 PF07690.16 KIY46867.1 - 0.018 14.0 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF4381 PF14316.6 KIY46867.1 - 0.019 15.2 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Peptidase_M56 PF05569.11 KIY46867.1 - 0.035 13.3 0.0 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 TMEM154 PF15102.6 KIY46867.1 - 0.036 14.0 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family TMEM156 PF15106.6 KIY46867.1 - 0.046 13.1 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 TMEM156 protein family RCR PF12273.8 KIY46867.1 - 0.075 13.7 0.2 0.1 13.3 0.2 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MFS_2 PF13347.6 KIY46867.1 - 0.076 11.6 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF4834 PF16118.5 KIY46867.1 - 0.11 13.5 0.0 0.15 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2615 PF11027.8 KIY46867.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF4051 PF13260.6 KIY46867.1 - 0.12 12.2 3.2 0.19 11.5 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) LYRIC PF15686.5 KIY46867.1 - 0.15 11.5 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF5385 PF17359.2 KIY46867.1 - 0.16 11.5 0.2 0.23 11.0 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Vpu PF00558.19 KIY46867.1 - 0.19 11.5 1.3 0.29 10.9 1.3 1.2 1 0 0 1 1 1 0 Vpu protein FeoB_associated PF12669.7 KIY46867.1 - 0.2 12.1 2.4 0.31 11.5 2.4 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SARAF PF06682.12 KIY46867.1 - 0.22 11.1 0.0 0.26 10.9 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis BatD PF13584.6 KIY46867.1 - 0.22 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF3290 PF11694.8 KIY46867.1 - 0.22 11.5 0.8 0.32 11.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Stevor PF17410.2 KIY46867.1 - 0.26 10.8 0.1 0.31 10.5 0.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3810 PF12725.7 KIY46867.1 - 0.3 10.4 0.0 0.37 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) tRNA_Me_trans PF03054.16 KIY46868.1 - 1.3e-112 376.1 0.0 1.5e-112 376.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KIY46868.1 - 0.0023 17.1 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 2 NAD synthase IL2 PF00715.17 KIY46869.1 - 7.7e-05 22.7 0.5 0.16 11.9 0.0 2.2 1 1 1 2 2 2 2 Interleukin 2 TolA_bind_tri PF16331.5 KIY46869.1 - 0.00037 20.5 1.0 0.0072 16.4 1.0 2.4 2 0 0 2 2 2 1 TolA binding protein trimerisation Spc7 PF08317.11 KIY46869.1 - 0.0069 15.3 5.5 0.0069 15.3 5.5 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein GIT_CC PF16559.5 KIY46869.1 - 0.0076 16.1 0.2 5.9 6.8 0.1 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HAP1_N PF04849.13 KIY46869.1 - 0.01 15.1 2.1 0.026 13.8 1.6 2.0 2 1 0 2 2 1 0 HAP1 N-terminal conserved region Atg14 PF10186.9 KIY46869.1 - 0.017 14.3 3.6 0.16 11.0 2.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 KIY46869.1 - 0.026 15.0 0.7 0.32 11.5 0.0 2.5 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 KIY46869.1 - 0.032 14.5 3.6 0.032 14.5 3.6 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) KASH_CCD PF14662.6 KIY46869.1 - 0.058 13.2 7.8 0.45 10.3 7.8 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 KIY46869.1 - 0.061 13.4 6.7 0.038 14.0 1.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.21 KIY46869.1 - 0.086 12.4 9.4 0.99 8.9 9.4 1.9 1 1 0 1 1 1 0 Intermediate filament protein DUF4482 PF14818.6 KIY46869.1 - 0.12 13.2 3.5 1 10.2 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) ZapB PF06005.12 KIY46869.1 - 0.13 12.7 5.3 0.35 11.3 1.9 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Hydrolase PF00702.26 KIY46869.1 - 0.15 12.3 0.3 4.4 7.5 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ATG16 PF08614.11 KIY46869.1 - 0.15 12.2 8.3 0.11 12.7 5.2 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 KIY46869.1 - 0.17 12.0 3.8 0.3 11.2 1.5 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 EspB PF05802.11 KIY46869.1 - 0.21 11.5 4.3 0.35 10.8 4.3 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein TMF_DNA_bd PF12329.8 KIY46869.1 - 0.23 11.5 11.1 0.59 10.2 4.7 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HHH_8 PF14716.6 KIY46869.1 - 0.24 11.8 2.3 1.5 9.3 0.4 2.8 1 1 2 3 3 3 0 Helix-hairpin-helix domain Cluap1 PF10234.9 KIY46869.1 - 0.26 10.7 6.3 0.38 10.1 6.3 1.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF948 PF06103.11 KIY46869.1 - 0.27 11.5 0.8 2.4 8.5 0.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 KIY46869.1 - 0.45 9.9 8.9 0.072 12.6 4.8 1.6 1 1 0 2 2 2 0 Golgin subfamily A member 5 DUF4795 PF16043.5 KIY46869.1 - 0.54 9.8 5.2 0.26 10.9 1.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PEARLI-4 PF05278.12 KIY46869.1 - 0.63 9.6 8.0 0.05 13.2 3.1 1.6 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF724 PF05266.14 KIY46869.1 - 0.79 9.5 9.0 2.7 7.8 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) MerR-DNA-bind PF09278.11 KIY46869.1 - 1 9.9 7.6 5.4 7.6 3.3 3.2 2 1 1 3 3 3 0 MerR, DNA binding APG6_N PF17675.1 KIY46869.1 - 1.1 9.8 6.4 1.3 9.6 4.6 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region PHM7_cyt PF14703.6 KIY46869.1 - 1.8 8.8 7.0 13 6.0 1.9 2.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter LURAP PF14854.6 KIY46869.1 - 2.1 8.3 4.7 48 3.9 0.4 3.6 2 1 2 4 4 4 0 Leucine rich adaptor protein DivIC PF04977.15 KIY46869.1 - 2.6 7.9 10.0 2.5 7.9 4.1 3.0 2 1 1 3 3 3 0 Septum formation initiator CLZ PF16526.5 KIY46869.1 - 2.7 8.4 7.9 1.8 9.0 3.7 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 KIY46869.1 - 2.9 8.4 6.1 6.9 7.2 1.2 2.6 3 0 0 3 3 2 0 Snapin/Pallidin DUF4618 PF15397.6 KIY46869.1 - 3.3 7.0 7.7 1.9 7.9 4.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF5082 PF16888.5 KIY46869.1 - 3.4 8.0 6.3 4.2 7.7 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Syntaxin PF00804.25 KIY46869.1 - 4.7 6.8 9.4 5.6 6.6 3.3 2.6 1 1 1 2 2 2 0 Syntaxin Rx_N PF18052.1 KIY46869.1 - 6.6 7.1 7.8 30 5.0 0.1 3.3 2 2 0 2 2 2 0 Rx N-terminal domain DUF16 PF01519.16 KIY46869.1 - 7 7.2 5.9 99 3.5 5.9 2.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.9 KIY46869.1 - 7.8 6.8 8.7 0.32 11.2 2.1 2.1 3 0 0 3 3 1 0 Haemolysin XhlA GAS PF13851.6 KIY46869.1 - 8 5.8 12.4 0.77 9.1 4.1 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4355 PF14265.6 KIY46869.1 - 9.8 6.4 10.9 0.49 10.7 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) WD40 PF00400.32 KIY46870.1 - 2.3e-23 82.0 2.1 7.9e-07 29.7 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY46870.1 - 1.9e-05 24.9 0.2 0.055 13.8 0.1 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY46870.1 - 0.016 13.9 0.0 0.12 10.9 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY46870.1 - 0.028 13.8 0.0 0.11 11.8 0.0 1.9 1 1 1 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 KIY46870.1 - 0.14 10.7 0.1 0.26 9.8 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40 PF00400.32 KIY46871.1 - 0.67 10.9 10.6 4.6 8.3 0.0 5.0 5 1 0 5 5 5 0 WD domain, G-beta repeat p450 PF00067.22 KIY46872.1 - 1.8e-56 191.8 0.0 2.4e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.13 KIY46873.1 - 5.4e-09 35.0 17.0 7.9e-09 34.5 17.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KIY46873.1 - 0.00044 19.3 45.4 0.007 15.3 43.8 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TMEM65 PF10507.9 KIY46873.1 - 0.17 11.8 5.2 1 9.3 0.4 3.1 2 1 1 3 3 3 0 Transmembrane protein 65 Mntp PF02659.15 KIY46873.1 - 0.46 10.2 14.2 0.18 11.6 6.9 3.2 2 1 0 2 2 2 0 Putative manganese efflux pump CENP-C_C PF11699.8 KIY46874.1 - 9.9e-22 77.0 0.0 1.5e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KIY46874.1 - 2e-06 27.4 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KIY46874.1 - 0.018 14.7 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Cupin DTHCT PF08070.11 KIY46875.1 - 0.51 11.1 5.9 1 10.1 4.3 2.4 2 1 0 2 2 2 0 DTHCT (NUC029) region DUF4611 PF15387.6 KIY46875.1 - 9.2 6.6 18.6 2.9 8.2 2.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4611) FAD_binding_3 PF01494.19 KIY46876.1 - 8.3e-13 48.3 1.6 1.7e-11 44.0 1.6 2.2 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KIY46876.1 - 8.1e-09 34.8 0.1 1.9e-05 23.7 0.0 3.0 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KIY46876.1 - 3.4e-05 23.9 0.1 0.036 14.0 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIY46876.1 - 0.0011 19.2 0.1 0.0033 17.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIY46876.1 - 0.0011 18.3 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KIY46876.1 - 0.012 14.9 0.2 0.17 11.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY46876.1 - 0.03 13.0 0.0 0.18 10.5 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIY46876.1 - 0.038 13.2 1.2 1.5 8.0 0.7 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CoaE PF01121.20 KIY46877.1 - 4.4e-33 114.4 0.0 7.1e-29 100.7 0.0 2.1 1 1 1 2 2 2 2 Dephospho-CoA kinase p450 PF00067.22 KIY46879.1 - 1.2e-56 192.4 0.0 1.8e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NDUFV3 PF15880.5 KIY46879.1 - 0.14 12.2 0.0 0.44 10.6 0.1 1.8 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial zf-C3HC4_3 PF13920.6 KIY46880.1 - 1.4e-05 24.9 8.0 1.4e-05 24.9 8.0 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.6 KIY46880.1 - 0.05 13.4 0.7 0.83 9.5 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY46880.1 - 0.1 13.1 17.8 12 6.5 1.9 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type HMG_box_2 PF09011.10 KIY46882.1 - 0.013 16.1 0.0 0.021 15.4 0.0 1.3 1 0 0 1 1 1 0 HMG-box domain CCDC144C PF14915.6 KIY46883.1 - 0.058 12.5 0.1 0.083 12.0 0.1 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region KASH_CCD PF14662.6 KIY46883.1 - 0.25 11.1 1.4 3.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 KIY46883.1 - 0.54 10.1 3.2 2.5 7.9 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator LPD38 PF18857.1 KIY46884.1 - 0.065 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 KDZ PF18758.1 KIY46885.1 - 1.5e-20 73.8 0.4 2.3e-20 73.2 0.0 1.5 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY46885.1 - 0.0045 17.1 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY46885.1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY46885.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY46886.1 - 2.2e-39 135.4 0.1 3.4e-39 134.8 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Flavi_NS4A PF01350.17 KIY46886.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A RHH_1 PF01402.21 KIY46887.1 - 0.5 10.4 4.6 3.8 7.6 2.1 3.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family CENP-F_leu_zip PF10473.9 KIY46887.1 - 7.4 6.6 7.9 4.6 7.3 0.1 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SPX PF03105.19 KIY46888.1 - 1.3 8.8 17.4 2 8.2 17.4 1.5 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KIY46888.1 - 6.1 5.9 25.2 9.3 5.3 25.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Cu-oxidase PF00394.22 KIY46889.1 - 8.6e-36 123.4 0.0 2.2e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY46889.1 - 5.7e-33 113.5 2.4 9e-33 112.8 1.5 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY46889.1 - 9.7e-29 99.8 3.1 2e-24 85.9 0.2 3.3 3 0 0 3 3 3 2 Multicopper oxidase Sulfatase PF00884.23 KIY46890.1 - 0.0087 15.5 0.0 0.0088 15.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Dicty_REP PF05086.12 KIY46890.1 - 0.084 10.9 0.1 0.096 10.6 0.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Transposase_21 PF02992.14 KIY46892.1 - 6.4e-06 25.6 0.1 8.1e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Transposase family tnp2 MA3 PF02847.17 KIY46893.1 - 0.0047 16.9 0.1 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 MA3 domain TFIIF_alpha PF05793.12 KIY46893.1 - 0.083 11.5 1.7 0.11 11.0 1.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IMUP PF15761.5 KIY46893.1 - 0.13 13.0 5.5 0.24 12.1 4.5 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein AF-4 PF05110.13 KIY46893.1 - 0.34 9.0 4.4 0.42 8.7 4.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FSA_C PF10479.9 KIY46895.1 - 0.36 8.9 0.6 0.44 8.6 0.6 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus BURP PF03181.15 KIY46897.1 - 0.13 11.8 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 BURP domain WLM PF08325.10 KIY46900.1 - 2.6e-39 135.3 0.9 2.6e-39 135.3 0.9 1.7 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 KIY46900.1 - 1.1e-08 34.6 0.0 2.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 KIY46900.1 - 0.0076 16.2 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain SprT-like PF10263.9 KIY46900.1 - 0.46 10.4 5.7 1.8 8.4 5.7 2.1 1 1 0 1 1 1 0 SprT-like family Rsa3 PF14615.6 KIY46901.1 - 9.8e-14 50.7 0.1 1.1e-12 47.3 0.1 2.1 1 1 0 1 1 1 1 Ribosome-assembly protein 3 RT_RNaseH_2 PF17919.1 KIY46904.1 - 5.4e-28 97.0 0.0 8.5e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIY46904.1 - 1e-26 93.2 0.0 1.7e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Arylsulfotran_2 PF14269.6 KIY46906.1 - 4e-38 131.5 0.1 5.1e-38 131.1 0.1 1.0 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY46906.1 - 6.2e-17 61.6 1.1 3.7e-15 55.7 1.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Yip1 PF04893.17 KIY46907.1 - 3.2e-14 53.0 15.9 4.4e-14 52.6 15.9 1.2 1 0 0 1 1 1 1 Yip1 domain IlvN PF07991.12 KIY46908.1 - 2e-46 157.6 0.0 3.4e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KIY46908.1 - 5.3e-39 133.8 0.0 8.6e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ApbA_C PF08546.11 KIY46911.1 - 1.2e-18 67.5 0.0 1.1e-15 57.9 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KIY46911.1 - 1e-13 51.2 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KIY46911.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Nif11 PF07862.11 KIY46911.1 - 0.14 12.5 0.1 3.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Nif11 domain HCO3_cotransp PF00955.21 KIY46913.1 - 3.6e-73 247.1 5.3 2.5e-38 132.2 0.1 2.7 1 1 1 2 2 2 2 HCO3- transporter family gag_pre-integrs PF13976.6 KIY46916.1 - 2.9e-05 23.8 0.1 3.8e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Roughex PF06020.11 KIY46919.1 - 1.6 7.8 6.9 1 8.4 2.1 2.3 2 0 0 2 2 2 0 Drosophila roughex protein Plasmodium_Vir PF05795.11 KIY46919.1 - 6.4 6.1 5.1 0.89 8.9 0.7 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SKG6 PF08693.10 KIY46920.1 - 0.28 10.6 3.4 0.29 10.6 0.1 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Phos_pyr_kin PF08543.12 KIY46921.1 - 2.2e-86 289.2 0.2 5.9e-63 212.5 0.0 2.2 1 1 1 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KIY46921.1 - 9e-41 140.0 0.3 1.4e-40 139.4 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KIY46921.1 - 4.3e-07 29.5 0.0 0.00079 18.8 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase tRNA-synt_1b PF00579.25 KIY46922.1 - 4e-66 223.3 0.0 7.5e-66 222.4 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HNH_2 PF13391.6 KIY46924.1 - 0.0019 18.3 0.1 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease DUF5523 PF17661.1 KIY46924.1 - 0.059 13.1 4.9 0.025 14.3 2.5 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Nop14 PF04147.12 KIY46924.1 - 1.9 6.6 11.2 2.4 6.3 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KIY46924.1 - 4 5.6 9.6 5.4 5.2 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Arylsulfotran_2 PF14269.6 KIY46928.1 - 6.8e-41 140.6 0.1 9.4e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY46928.1 - 8.3e-15 54.6 0.3 1.2e-13 50.8 0.3 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) p450 PF00067.22 KIY46929.1 - 0.0038 16.0 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY46932.1 - 1.2e-60 205.6 0.0 1.6e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIY46933.1 - 1.4 9.9 3.7 1.5e+02 3.5 2.0 4.6 3 1 0 3 3 3 0 WD domain, G-beta repeat FAD_binding_3 PF01494.19 KIY46934.1 - 2.2e-13 50.2 1.3 3.6e-12 46.2 1.3 2.2 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KIY46934.1 - 1.8e-06 27.1 0.0 0.0013 17.7 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KIY46934.1 - 2.9e-05 24.1 0.1 0.036 14.0 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIY46934.1 - 0.0011 19.1 0.1 0.0033 17.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIY46934.1 - 0.0025 17.2 0.0 0.0056 16.0 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KIY46934.1 - 0.016 14.5 0.2 0.17 11.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY46934.1 - 0.032 12.9 0.1 0.18 10.5 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIY46934.1 - 0.04 13.2 1.3 1.5 8.0 0.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CENP-C_C PF11699.8 KIY46935.1 - 3.4e-16 59.2 0.0 4.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KIY46935.1 - 0.003 17.3 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain PBP1_TM PF14812.6 KIY46935.1 - 0.099 13.0 1.5 0.16 12.3 0.2 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 KIY46936.1 - 6.8e-10 38.4 53.1 2.1e-08 33.5 51.5 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY46936.1 - 3e-07 29.3 23.3 4.6e-07 28.6 23.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UxuA PF03786.13 KIY46936.1 - 0.22 10.3 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) TMEM65 PF10507.9 KIY46936.1 - 0.33 10.9 6.4 0.51 10.3 0.7 3.2 2 1 1 3 3 3 0 Transmembrane protein 65 MFS_1 PF07690.16 KIY46937.1 - 1.8e-22 79.8 28.0 1.8e-22 79.8 28.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY46937.1 - 3.7e-16 59.0 19.2 4.4e-15 55.5 19.1 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter 7TM-7TMR_HD PF07698.11 KIY46937.1 - 0.015 15.1 1.2 0.015 15.1 1.2 3.0 3 1 0 3 3 3 0 7TM receptor with intracellular HD hydrolase FAA_hydrolase PF01557.18 KIY46938.1 - 1.3e-58 198.2 0.0 1.6e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 KIY46938.1 - 0.0046 16.8 3.2 0.018 14.8 0.3 2.3 1 1 1 2 2 2 1 KH domain CelD_N PF02927.14 KIY46938.1 - 0.012 16.5 0.0 0.027 15.3 0.0 1.6 1 0 0 1 1 1 0 Cellulase N-terminal ig-like domain RRM_1 PF00076.22 KIY46939.1 - 7.3e-08 32.1 0.0 0.00044 20.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_term_smal PF05944.12 KIY46939.1 - 0.04 13.9 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Phage small terminase subunit IBR PF01485.21 KIY46940.1 - 1.6e-16 60.3 17.5 2.3e-11 43.8 2.4 3.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KIY46940.1 - 0.00056 19.9 6.7 0.00056 19.9 6.7 4.4 3 1 0 3 3 3 1 RING-type zinc-finger zf_CopZ PF18423.1 KIY46940.1 - 0.00069 19.5 1.1 0.00069 19.5 1.1 4.8 5 1 0 5 5 5 1 Zinc binding domain zf-C2H2_2 PF12756.7 KIY46940.1 - 4 7.8 13.0 22 5.5 11.4 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) p450 PF00067.22 KIY46941.1 - 6.9e-56 189.9 0.0 7.8e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COX4 PF02936.14 KIY46942.1 - 4.9e-40 136.7 0.1 5.8e-40 136.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Gly-rich_Ago1 PF12764.7 KIY46942.1 - 0.038 14.8 3.3 0.081 13.7 3.3 1.5 1 0 0 1 1 1 0 Glycine-rich region of argonaut DUF3106 PF11304.8 KIY46942.1 - 0.039 14.4 2.6 0.051 14.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) MitMem_reg PF13012.6 KIY46943.1 - 2.7e-34 117.9 1.1 4.4e-34 117.3 1.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KIY46943.1 - 2.7e-29 101.5 0.0 5e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease T6SS_VipA PF05591.12 KIY46943.1 - 0.052 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 HIT PF01230.23 KIY46944.1 - 4.6e-18 65.8 0.0 1.5e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIY46944.1 - 0.0005 20.5 0.0 0.0029 18.1 0.0 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SAPS PF04499.15 KIY46945.1 - 5.6e-119 398.1 0.0 9.4e-119 397.4 0.0 1.4 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein ANAPC5 PF12862.7 KIY46945.1 - 0.17 12.0 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 FAD_binding_3 PF01494.19 KIY46947.1 - 1e-12 48.0 0.3 2.8e-07 30.1 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KIY46947.1 - 0.00028 21.0 0.6 0.00056 20.1 0.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY46947.1 - 0.0055 16.0 0.6 0.02 14.1 0.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIY46947.1 - 0.0064 15.6 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 KIY46947.1 - 0.0073 15.9 1.0 0.015 14.9 1.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY46947.1 - 0.036 14.1 0.4 1.4 8.9 0.6 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KIY46947.1 - 0.04 12.8 0.8 0.23 10.3 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 KIY46947.1 - 0.11 13.1 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY46947.1 - 0.17 10.5 1.0 0.29 9.8 1.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Adap_comp_sub PF00928.21 KIY46948.1 - 9.2e-83 277.6 0.1 1.2e-82 277.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIY46948.1 - 1.4e-06 28.3 3.4 2.4e-06 27.5 3.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF11 PF01345.18 KIY46948.1 - 0.035 14.4 4.5 0.095 13.0 4.5 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF11 muHD PF10291.9 KIY46948.1 - 0.076 12.4 0.3 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Nuc_sug_transp PF04142.15 KIY46949.1 - 5.7e-95 318.1 7.4 3.6e-94 315.4 7.4 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 KIY46949.1 - 0.00032 20.0 1.0 0.00032 20.0 1.0 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 KIY46949.1 - 0.00033 20.8 7.6 0.00033 20.8 7.6 3.0 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.11 KIY46949.1 - 0.00063 19.0 8.9 0.0098 15.1 8.9 2.2 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 KIY46949.1 - 0.014 14.8 2.7 0.014 14.8 2.7 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family Sulf_transp PF04143.14 KIY46949.1 - 0.18 11.4 10.0 0.18 11.4 4.8 2.6 1 1 1 2 2 2 0 Sulphur transport Mit_ribos_Mrp51 PF11709.8 KIY46950.1 - 3.2e-09 36.9 0.2 1.6e-08 34.6 0.2 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Acyl-CoA_ox_N PF14749.6 KIY46950.1 - 0.15 12.6 1.4 5.9 7.5 0.4 2.4 2 1 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal MMM1 PF10296.9 KIY46951.1 - 7.2e-09 35.1 0.0 2.9e-05 23.3 0.0 2.9 3 0 0 3 3 3 2 Maintenance of mitochondrial morphology protein 1 KIF1B PF12423.8 KIY46951.1 - 0.11 12.9 0.7 0.2 12.1 0.7 1.4 1 0 0 1 1 1 0 Kinesin protein 1B Radical_SAM_C PF16199.5 KIY46952.1 - 3.6e-30 103.8 0.0 7.1e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KIY46952.1 - 5.5e-16 59.4 0.0 1.5e-15 58.0 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KIY46952.1 - 3.2e-09 37.0 0.0 7.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY46952.1 - 2.3e-06 27.6 0.0 5.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY46952.1 - 0.0021 18.4 0.0 0.0096 16.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY46952.1 - 0.079 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Gemini_mov PF01708.16 KIY46953.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Cyclin_N PF00134.23 KIY46954.1 - 9.5e-05 22.2 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY46954.1 - 0.0035 17.7 0.1 0.0075 16.6 0.1 1.4 1 1 1 2 2 2 1 Cyclin GDA1_CD39 PF01150.17 KIY46957.1 - 6.2e-104 348.0 0.0 7.6e-103 344.4 0.0 1.9 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KIY46957.1 - 0.068 12.6 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family TPP_enzyme_N PF02776.18 KIY46958.1 - 5.9e-54 182.3 0.0 1.6e-53 180.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIY46958.1 - 4.5e-46 156.4 0.7 4.5e-45 153.2 0.1 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIY46958.1 - 1.7e-41 141.2 0.4 3.7e-41 140.1 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fungal_trans PF04082.18 KIY46961.1 - 2e-16 59.8 0.4 4.4e-16 58.7 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY46961.1 - 6.1e-06 26.3 8.1 1.5e-05 25.0 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Egg_lysin PF01303.17 KIY46961.1 - 0.099 12.9 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) CUE PF02845.16 KIY46962.1 - 0.0084 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain MR_MLE_C PF13378.6 KIY46962.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Enolase C-terminal domain-like HOIP-UBA PF16678.5 KIY46962.1 - 0.053 13.5 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 HOIP UBA domain pair IML1 PF12257.8 KIY46963.1 - 5.7e-107 357.1 0.0 8.3e-107 356.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KIY46963.1 - 2.2e-15 56.5 0.2 4.8e-15 55.4 0.2 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf-C4H2 PF10146.9 KIY46964.1 - 1.4e-08 35.3 1.6 1.8e-08 34.9 1.6 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein DUF3450 PF11932.8 KIY46964.1 - 0.0038 16.6 2.4 0.0051 16.1 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4047 PF13256.6 KIY46964.1 - 0.011 15.9 0.2 0.016 15.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Asp_Glu_race PF01177.22 KIY46964.1 - 0.023 14.5 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Atg14 PF10186.9 KIY46964.1 - 0.028 13.5 6.9 0.037 13.1 6.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Menin PF05053.13 KIY46964.1 - 0.037 12.4 0.7 0.045 12.1 0.4 1.3 1 1 0 1 1 1 0 Menin T3SSipB PF16535.5 KIY46964.1 - 0.04 14.4 3.1 0.054 14.0 3.1 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB AAA_31 PF13614.6 KIY46964.1 - 0.052 13.5 0.2 0.065 13.1 0.2 1.2 1 0 0 1 1 1 0 AAA domain COG2 PF06148.11 KIY46964.1 - 0.29 11.2 2.6 0.4 10.8 1.9 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 KIY46964.1 - 1.2 9.4 11.1 0.069 13.4 6.2 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Ant_C PF05586.11 KIY46965.1 - 0.12 12.9 0.2 0.51 11.0 0.2 1.9 1 1 0 1 1 1 0 Anthrax receptor C-terminus region Cyclin_N PF00134.23 KIY46966.1 - 1e-09 38.2 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY46966.1 - 1.2e-06 29.0 0.1 1.8e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin SelP_N PF04592.14 KIY46966.1 - 1.4 8.2 9.1 2.1 7.7 9.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3429 PF11911.8 KIY46967.1 - 8.6e-40 136.4 17.9 1.2e-39 135.9 17.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Na_H_Exchanger PF00999.21 KIY46967.1 - 0.0084 14.9 3.1 0.027 13.3 2.7 1.8 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family Terpene_synth_C PF03936.16 KIY46968.1 - 2.5e-08 33.6 0.0 3.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KIY46968.1 - 3.8e-06 26.0 0.1 2.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) Melibiase_2_C PF17450.2 KIY46970.1 - 0.2 11.9 0.0 0.33 11.2 0.0 1.5 1 1 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain Pro_isomerase PF00160.21 KIY46971.1 - 1.2e-52 178.4 0.0 1.3e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bac_export_2 PF01312.19 KIY46972.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.4 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Exo_endo_phos PF03372.23 KIY46973.1 - 2.9e-05 23.7 0.2 0.00016 21.3 0.2 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.17 KIY46973.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Jacalin-like lectin domain GalP_UDP_tr_C PF02744.17 KIY46973.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Terpene_synth_C PF03936.16 KIY46974.1 - 3.2e-08 33.2 0.0 4.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KIY46974.1 - 2e-06 26.9 0.0 2.1e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) NUDIX PF00293.28 KIY46975.1 - 3.3e-05 24.0 0.0 5.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain HMG_box_2 PF09011.10 KIY46977.1 - 0.0052 17.3 0.2 0.012 16.2 0.0 1.6 2 0 0 2 2 2 1 HMG-box domain KDZ PF18758.1 KIY46978.1 - 8.5e-39 133.5 0.1 1.3e-38 132.9 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CFTR_R PF14396.6 KIY46978.1 - 0.065 12.8 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain KDZ PF18758.1 KIY46979.1 - 4.1e-18 65.8 0.3 9.8e-18 64.6 0.0 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY46979.1 - 0.0037 17.4 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY46979.1 - 0.029 14.5 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases DUF3106 PF11304.8 KIY46979.1 - 0.17 12.4 4.3 2.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) LPD38 PF18857.1 KIY46982.1 - 0.068 13.3 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Large polyvalent protein associated domain 38 HMG_box_2 PF09011.10 KIY46984.1 - 8e-06 26.4 0.7 4.5e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 HMG-box domain DUF1178 PF06676.11 KIY46984.1 - 0.039 14.3 0.1 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) DUF1266 PF06889.11 KIY46984.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Gluconate_2-dh3 PF13618.6 KIY46984.1 - 0.059 13.6 0.5 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Hepar_II_III PF07940.13 KIY46984.1 - 0.066 12.8 0.2 0.085 12.5 0.2 1.1 1 0 0 1 1 1 0 Heparinase II/III-like protein PSII_Pbs27 PF13326.6 KIY46984.1 - 1.1 9.6 4.9 0.76 10.1 0.9 2.2 2 1 0 3 3 3 0 Photosystem II Pbs27 Meth_synt_2 PF01717.18 KIY46985.1 - 9e-16 58.0 0.0 4.1e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIY46985.1 - 0.02 14.4 0.0 0.89 9.0 0.0 2.2 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Kdo PF06293.14 KIY46988.1 - 0.018 14.4 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Helicase_C PF00271.31 KIY46990.1 - 1e-10 41.9 0.0 1.3e-09 38.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY46990.1 - 1e-09 38.4 0.0 5.1e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY46990.1 - 4.4e-06 26.8 0.0 8.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIY46990.1 - 0.017 15.4 0.0 0.054 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain FTA2 PF13095.6 KIY46991.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Dimer_Tnp_hAT PF05699.14 KIY46992.1 - 3.6e-16 58.7 0.0 6.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIY46992.1 - 0.14 12.6 0.2 1.1 9.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4413) zf-CCHC_4 PF14392.6 KIY46994.1 - 0.0011 18.7 0.5 0.0019 17.9 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY46994.1 - 0.052 13.6 3.7 0.12 12.5 3.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 KIY46994.1 - 0.19 11.6 4.2 0.43 10.5 4.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Glyco_transf_15 PF01793.16 KIY46996.1 - 4.1e-13 49.3 0.0 4.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ABC_tran PF00005.27 KIY46997.1 - 2.7e-36 125.1 0.0 7.1e-18 65.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KIY46997.1 - 4.5e-22 77.9 5.4 4.5e-22 77.9 5.4 2.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KIY46997.1 - 2.2e-11 44.1 5.1 0.0019 18.1 0.0 4.0 5 0 0 5 5 3 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIY46997.1 - 9.7e-08 32.1 0.4 0.0056 16.8 0.3 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIY46997.1 - 3.2e-07 30.0 0.0 0.0095 15.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIY46997.1 - 2.1e-06 27.8 0.0 0.048 13.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KIY46997.1 - 4.7e-06 26.2 0.1 0.83 9.0 0.0 4.3 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIY46997.1 - 1.5e-05 24.9 8.5 0.039 13.6 0.1 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 KIY46997.1 - 1.9e-05 25.2 0.4 0.73 10.4 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_28 PF13521.6 KIY46997.1 - 3.6e-05 24.1 0.5 0.094 13.0 0.1 3.1 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KIY46997.1 - 5.5e-05 23.5 0.3 0.65 10.3 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 KIY46997.1 - 6.6e-05 23.3 0.9 0.47 10.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KIY46997.1 - 0.00011 22.1 0.1 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 KIY46997.1 - 0.00019 22.0 12.8 0.017 15.7 0.0 4.4 5 0 0 5 5 4 2 AAA domain MeaB PF03308.16 KIY46997.1 - 0.00029 19.9 1.3 0.077 12.0 0.0 2.6 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KIY46997.1 - 0.00067 19.4 0.1 2.6 7.7 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.6 KIY46997.1 - 0.00069 19.8 0.2 0.94 9.6 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KIY46997.1 - 0.006 17.0 0.2 22 5.5 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIY46997.1 - 0.007 16.3 0.1 2.2 8.2 0.1 2.7 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KIY46997.1 - 0.0092 16.4 0.1 6.5 7.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KIY46997.1 - 0.011 15.4 0.3 3 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KIY46997.1 - 0.012 14.9 0.7 4.8 6.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 KIY46997.1 - 0.012 15.9 0.0 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KIY46997.1 - 0.016 15.3 0.6 1 9.4 0.1 3.1 2 1 1 3 3 3 0 Dynamin family DUF87 PF01935.17 KIY46997.1 - 0.017 15.2 7.5 0.024 14.7 0.1 3.4 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_14 PF13173.6 KIY46997.1 - 0.022 14.8 0.8 13 5.9 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_7 PF12775.7 KIY46997.1 - 0.023 14.2 0.0 7.5 6.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KIY46997.1 - 0.053 12.7 0.0 1.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF3584 PF12128.8 KIY46997.1 - 0.058 10.9 0.0 0.058 10.9 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) cobW PF02492.19 KIY46997.1 - 0.065 12.8 0.2 14 5.3 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KIY46997.1 - 0.074 12.6 0.2 13 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KIY46997.1 - 0.09 12.8 0.5 5.2 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KIY46997.1 - 0.11 12.2 0.1 17 5.1 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KIY46997.1 - 0.11 12.0 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B dNK PF01712.19 KIY46997.1 - 0.28 11.0 2.2 16 5.3 0.0 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase NT-C2 PF10358.9 KIY46998.1 - 3.5e-15 56.0 0.0 1.1e-11 44.7 0.0 2.1 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins DUF1996 PF09362.10 KIY46999.1 - 4.9e-71 239.4 1.1 6.9e-71 239.0 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) COG6 PF06419.11 KIY47000.1 - 2.6e-134 448.8 0.0 3.8e-134 448.3 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 PAM2 PF07145.15 KIY47001.1 - 0.075 12.8 9.8 7.2 6.5 0.8 4.2 2 1 1 3 3 3 0 Ataxin-2 C-terminal region ATG16 PF08614.11 KIY47001.1 - 0.71 10.1 64.4 0.61 10.3 25.3 4.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Tup_N PF08581.10 KIY47001.1 - 1.8 8.9 27.1 0.33 11.3 4.8 5.5 4 2 0 5 5 5 0 Tup N-terminal Tropomyosin PF00261.20 KIY47001.1 - 4.5 6.6 51.7 0.0085 15.5 23.1 2.8 2 1 1 3 3 3 0 Tropomyosin NAD_binding_8 PF13450.6 KIY47003.1 - 1.2e-12 47.8 0.0 4.3e-12 46.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY47003.1 - 0.005 16.8 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KIY47003.1 - 0.0081 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY47003.1 - 0.02 14.0 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KIY47003.1 - 0.028 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KIY47003.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DDOST_48kD PF03345.14 KIY47003.1 - 0.43 9.4 1.0 0.68 8.7 1.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta DUF4211 PF13926.6 KIY47004.1 - 1.6e-05 25.0 0.5 8.5e-05 22.6 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) DOT1 PF08123.13 KIY47005.1 - 1.7e-62 210.6 0.0 2.2e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 KIY47005.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIY47005.1 - 0.043 14.5 0.0 0.08 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIY47005.1 - 0.096 12.5 0.0 0.53 10.1 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain ADH_zinc_N PF00107.26 KIY47005.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CMAS PF02353.20 KIY47005.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DPBB_1 PF03330.18 KIY47006.1 - 8.2e-06 26.0 0.1 2.7e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Lytic transglycolase DPBB_1 PF03330.18 KIY47007.1 - 8.2e-08 32.4 0.2 3.5e-07 30.4 0.2 2.2 1 1 0 1 1 1 1 Lytic transglycolase Ipi1_N PF12333.8 KIY47008.1 - 4.6e-21 75.3 0.0 3.6e-20 72.5 0.0 2.5 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation SRA1 PF07304.11 KIY47008.1 - 0.0033 17.2 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Amidohydro_3 PF07969.11 KIY47011.1 - 3.3e-76 257.6 0.1 4e-76 257.4 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIY47011.1 - 1.2e-09 38.0 0.0 2.5e-07 30.4 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family GTP_EFTU PF00009.27 KIY47012.1 - 7.8e-56 188.7 0.2 1.2e-55 188.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIY47012.1 - 2.6e-26 92.1 0.0 5e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIY47012.1 - 2.5e-16 59.8 3.5 5.7e-16 58.7 3.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY47012.1 - 2.6e-05 24.3 0.1 5.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY47012.1 - 0.003 17.5 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase PduV-EutP PF10662.9 KIY47012.1 - 0.018 14.8 0.4 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KIY47012.1 - 0.025 14.2 0.3 0.052 13.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pex14_N PF04695.13 KIY47013.1 - 9.6e-19 68.6 2.7 9.6e-19 68.6 2.7 3.9 2 2 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IFT57 PF10498.9 KIY47013.1 - 0.00035 19.7 1.9 0.00062 18.8 1.9 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 KIY47013.1 - 0.0013 18.8 2.1 0.0023 18.0 2.1 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 KIY47013.1 - 0.002 18.1 6.9 0.0036 17.3 6.9 1.3 1 0 0 1 1 1 1 Laminin Domain II TMPIT PF07851.13 KIY47013.1 - 0.0087 15.3 1.2 0.014 14.7 1.2 1.2 1 0 0 1 1 1 1 TMPIT-like protein LXG PF04740.12 KIY47013.1 - 0.015 15.0 6.5 0.024 14.3 6.5 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Fez1 PF06818.15 KIY47013.1 - 0.03 14.8 4.2 0.04 14.4 4.2 1.1 1 0 0 1 1 1 0 Fez1 Med9 PF07544.13 KIY47013.1 - 0.037 14.1 7.9 0.071 13.2 4.0 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FapA PF03961.13 KIY47013.1 - 0.045 12.4 0.9 0.061 11.9 0.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A BshC PF10079.9 KIY47013.1 - 0.046 12.5 3.6 0.066 12.0 3.6 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC GBP_C PF02841.14 KIY47013.1 - 0.054 12.9 6.3 0.074 12.5 6.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain LMBR1 PF04791.16 KIY47013.1 - 0.059 12.3 0.2 0.077 11.9 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Prominin PF05478.11 KIY47013.1 - 0.071 11.1 1.3 0.089 10.7 1.3 1.0 1 0 0 1 1 1 0 Prominin Apolipoprotein PF01442.18 KIY47013.1 - 0.12 12.3 13.3 0.37 10.6 12.9 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 KIY47013.1 - 0.17 12.4 8.3 5.2 7.6 7.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_holin_7_1 PF16081.5 KIY47013.1 - 0.22 11.7 3.3 0.24 11.6 1.5 2.0 2 0 0 2 2 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Uso1_p115_C PF04871.13 KIY47013.1 - 0.26 11.7 8.3 0.43 10.9 8.3 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 PF09787.9 KIY47013.1 - 0.27 10.7 9.3 0.41 10.1 9.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4192 PF13830.6 KIY47013.1 - 0.32 11.0 4.8 0.49 10.4 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DLP_helical PF18709.1 KIY47013.1 - 0.33 10.1 5.9 0.49 9.5 5.9 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain Tektin PF03148.14 KIY47013.1 - 0.33 9.7 9.3 0.5 9.1 9.3 1.2 1 0 0 1 1 1 0 Tektin family Spc7 PF08317.11 KIY47013.1 - 0.39 9.6 11.2 0.57 9.0 11.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 KIY47013.1 - 0.41 9.1 3.8 0.59 8.6 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 KIY47013.1 - 0.44 10.7 3.3 0.73 10.0 3.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 KIY47013.1 - 0.46 9.8 9.4 0.89 8.8 9.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TSNAXIP1_N PF15739.5 KIY47013.1 - 0.49 10.8 5.3 0.64 10.4 4.0 1.8 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF4407 PF14362.6 KIY47013.1 - 0.49 9.7 6.8 0.77 9.0 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KIY47013.1 - 0.49 10.9 10.7 0.89 10.1 10.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3584 PF12128.8 KIY47013.1 - 0.68 7.4 9.5 0.9 7.0 9.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 KIY47013.1 - 0.74 10.1 5.5 2.8 8.3 1.8 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 KIY47013.1 - 0.83 9.7 12.1 0.13 12.3 6.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ISG65-75 PF11727.8 KIY47013.1 - 0.99 8.6 7.5 2.7 7.1 7.2 1.6 1 1 1 2 2 2 0 Invariant surface glycoprotein Cortex-I_coil PF09304.10 KIY47013.1 - 1 9.6 6.5 0.19 11.9 1.2 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF1664 PF07889.12 KIY47013.1 - 1.2 9.2 10.7 0.24 11.5 6.3 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KIY47013.1 - 1.3 9.1 6.9 2 8.5 6.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 KIY47013.1 - 1.4 9.5 10.6 2.5 8.8 10.6 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1319 PF07028.11 KIY47013.1 - 1.5 9.1 4.7 3.6 7.9 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) TBCC_N PF16752.5 KIY47013.1 - 2.1 8.8 8.5 9.4 6.7 5.0 2.3 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain YabA PF06156.13 KIY47013.1 - 2.1 9.1 5.9 4.4 8.0 5.7 1.6 1 1 0 1 1 1 0 Initiation control protein YabA COG2 PF06148.11 KIY47013.1 - 2.2 8.4 9.6 5.3 7.1 1.3 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.21 KIY47013.1 - 2.4 8.7 9.1 1.5 9.4 4.6 2.1 1 1 1 2 2 2 0 Spectrin repeat RmuC PF02646.16 KIY47013.1 - 2.8 7.0 9.0 0.78 8.8 3.4 2.0 1 1 1 2 2 2 0 RmuC family THOC7 PF05615.13 KIY47013.1 - 3.1 8.1 9.9 5.8 7.2 9.7 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 OmpH PF03938.14 KIY47013.1 - 3.1 8.1 13.2 8.2 6.8 13.2 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) BST2 PF16716.5 KIY47013.1 - 4.5 7.9 8.1 1.7 9.3 4.1 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 TolA_bind_tri PF16331.5 KIY47013.1 - 5.3 7.2 11.7 18 5.5 0.1 3.2 1 1 2 3 3 3 0 TolA binding protein trimerisation eIF3_N PF09440.10 KIY47013.1 - 7.5 7.0 8.1 18 5.8 5.4 2.5 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain GRIP PF01465.20 KIY47015.1 - 1.3e-16 60.2 0.2 4.2e-16 58.6 0.2 2.0 1 0 0 1 1 1 1 GRIP domain zf-C4H2 PF10146.9 KIY47015.1 - 0.00015 22.2 6.8 0.00015 22.2 6.8 3.9 2 1 2 4 4 4 1 Zinc finger-containing protein BRE1 PF08647.11 KIY47015.1 - 0.0042 17.1 5.9 0.0042 17.1 5.9 5.7 2 2 3 5 5 5 1 BRE1 E3 ubiquitin ligase DUF2968 PF11180.8 KIY47015.1 - 0.012 15.2 10.0 0.012 15.2 10.0 5.6 1 1 3 5 5 5 0 Protein of unknown function (DUF2968) DUF3287 PF11690.8 KIY47015.1 - 0.96 9.2 10.7 7.6 6.3 4.6 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3287) TPR_4 PF07721.14 KIY47015.1 - 1 10.2 4.6 1.4 9.8 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Uteroglobin PF01099.17 KIY47015.1 - 3.7 8.0 5.9 8.6 6.8 0.4 3.0 2 0 0 2 2 2 0 Uteroglobin family DUF812 PF05667.11 KIY47015.1 - 6.5 5.5 69.8 1.2 7.9 15.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF812) GCV_H PF01597.19 KIY47017.1 - 5.7e-37 126.3 0.5 1.7e-25 89.2 0.2 2.1 2 0 0 2 2 2 2 Glycine cleavage H-protein RnfC_N PF13375.6 KIY47017.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KIY47017.1 - 0.051 13.4 0.2 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Biotin-requiring enzyme ESSS PF10183.9 KIY47018.1 - 9.2e-13 48.3 0.0 1.1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Acetyltransf_1 PF00583.25 KIY47019.1 - 3.4e-16 59.5 0.1 4.4e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY47019.1 - 3.8e-10 39.8 0.0 5.1e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY47019.1 - 6e-10 39.4 0.1 8.7e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY47019.1 - 3.4e-06 26.9 0.0 6.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KIY47019.1 - 0.00019 21.6 0.0 0.00022 21.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIY47019.1 - 0.0075 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_16 PF05301.11 KIY47019.1 - 0.035 13.9 0.0 0.085 12.6 0.0 1.7 1 1 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Acetyltransf_9 PF13527.7 KIY47019.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain XPA_C PF05181.12 KIY47020.1 - 0.00074 19.4 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 2 XPA protein C-terminus RIO1 PF01163.22 KIY47022.1 - 9.6e-49 165.5 0.0 1.4e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KIY47022.1 - 2.2e-33 114.3 0.1 3.9e-33 113.5 0.1 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KIY47022.1 - 3.1e-10 40.4 0.1 0.0012 18.9 0.1 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KIY47022.1 - 7.7e-07 28.7 0.0 2.8e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SMN PF06003.12 KIY47023.1 - 1.7e-08 34.0 3.0 2.3e-08 33.6 3.0 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KIY47023.1 - 3.5e-06 27.1 0.0 7.6e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Tudor domain Relaxase PF03432.14 KIY47023.1 - 0.0014 18.3 1.8 0.0014 18.3 1.8 1.5 2 0 0 2 2 2 1 Relaxase/Mobilisation nuclease domain Tudor_3 PF18115.1 KIY47023.1 - 0.0016 18.3 0.4 0.0033 17.2 0.0 1.8 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Med3 PF11593.8 KIY47023.1 - 0.03 13.5 2.3 0.033 13.4 2.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1325 PF07039.11 KIY47023.1 - 0.035 14.2 2.8 0.089 12.9 0.0 2.7 2 1 0 2 2 2 0 SGF29 tudor-like domain DUF4537 PF15057.6 KIY47023.1 - 0.048 13.7 0.1 0.098 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) PWWP PF00855.17 KIY47023.1 - 0.063 13.7 2.7 0.39 11.1 2.7 2.4 1 1 0 1 1 1 0 PWWP domain IBB PF01749.20 KIY47023.1 - 0.5 10.8 11.4 0.14 12.6 8.0 1.8 2 0 0 2 2 2 0 Importin beta binding domain Presenilin PF01080.17 KIY47023.1 - 1.8 7.3 3.2 2.1 7.0 3.2 1.2 1 0 0 1 1 1 0 Presenilin RRP36 PF06102.12 KIY47023.1 - 2.6 8.0 19.8 0.42 10.6 10.1 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DNA_pol_delta_4 PF04081.13 KIY47023.1 - 5.1 7.5 11.8 1.1 9.6 6.2 2.0 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 CBS PF00571.28 KIY47026.1 - 2.4e-24 85.5 4.0 1.2e-10 41.7 0.1 5.1 4 1 0 4 4 4 4 CBS domain Methyltransf_23 PF13489.6 KIY47028.1 - 4.5e-09 36.4 0.0 5.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY47028.1 - 0.00033 21.2 0.0 0.0011 19.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY47028.1 - 0.0015 19.2 0.0 0.005 17.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY47028.1 - 0.0032 18.2 0.1 0.013 16.2 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY47028.1 - 0.017 14.9 0.0 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PX PF00787.24 KIY47029.1 - 1.5e-17 63.6 0.0 2.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 PX domain MazG-like PF12643.7 KIY47029.1 - 0.13 12.5 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 MazG-like family SNARE PF05739.19 KIY47029.1 - 0.19 11.7 0.8 0.26 11.3 0.1 1.6 2 0 0 2 2 2 0 SNARE domain Tropomyosin PF00261.20 KIY47029.1 - 0.24 10.7 2.1 0.15 11.4 0.4 1.5 2 0 0 2 2 2 0 Tropomyosin Mito_carr PF00153.27 KIY47030.1 - 2.7e-55 184.3 0.2 1.7e-17 63.1 0.1 3.6 2 2 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIY47030.1 - 0.13 11.4 2.0 0.55 9.3 0.0 2.5 3 0 0 3 3 3 0 Gammaproteobacterial serine protease IF4E PF01652.18 KIY47031.1 - 1.9e-47 161.0 0.0 1.6e-46 158.0 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Pil1 PF13805.6 KIY47032.1 - 2.6e-46 158.3 3.5 2.6e-46 158.3 3.5 1.6 2 0 0 2 2 2 1 Eisosome component PIL1 FMO-like PF00743.19 KIY47033.1 - 2.2e-05 23.1 0.0 3.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY47033.1 - 0.2 10.8 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L17 PF01196.19 KIY47034.1 - 7.8e-34 116.5 0.2 2.3e-33 115.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 SGL PF08450.12 KIY47035.1 - 2.1e-65 220.7 0.0 3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIY47035.1 - 0.0052 16.9 0.0 0.032 14.3 0.0 2.1 2 0 0 2 2 2 1 Strictosidine synthase Ribosomal_L13 PF00572.18 KIY47036.1 - 1.6e-12 47.8 0.3 1.2e-10 41.7 0.0 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 KH_1 PF00013.29 KIY47037.1 - 5.5e-41 138.2 9.9 7.9e-16 57.6 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KIY47037.1 - 2e-09 37.2 4.9 0.019 14.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KIY47037.1 - 9e-09 35.1 0.3 0.1 12.5 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KIY47037.1 - 2.5e-05 24.3 3.7 0.1 12.7 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.19 KIY47037.1 - 0.04 13.6 0.4 4.3 7.0 0.1 2.6 2 1 0 2 2 2 0 dUTPase NUFIP1 PF10453.9 KIY47038.1 - 7.2e-16 57.8 0.5 1.2e-15 57.0 0.5 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) FoP_duplication PF13865.6 KIY47038.1 - 0.36 11.4 9.0 0.86 10.2 9.0 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF1857 PF08982.11 KIY47039.1 - 7.5e-43 145.9 0.3 7e-42 142.7 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1857) MFS_1 PF07690.16 KIY47040.1 - 4.8e-23 81.7 23.8 4.8e-23 81.7 23.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3923 PF13061.6 KIY47040.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3923) 2TM PF13239.6 KIY47040.1 - 7.9 6.9 9.2 9.6 6.6 0.0 3.9 4 1 0 4 4 4 0 2TM domain 2-Hacid_dh_C PF02826.19 KIY47041.1 - 7.6e-54 181.8 0.0 9.9e-54 181.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY47041.1 - 9.4e-12 44.7 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 KIY47041.1 - 0.086 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain DAO PF01266.24 KIY47042.1 - 3.5e-29 102.5 0.1 4.6e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY47042.1 - 3.1e-07 29.9 0.1 1.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY47042.1 - 6.9e-06 26.2 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIY47042.1 - 1e-05 24.9 0.1 2.1e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KIY47042.1 - 3e-05 23.3 1.1 7.4e-05 22.0 1.1 1.6 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIY47042.1 - 6.5e-05 22.2 0.2 0.017 14.2 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KIY47042.1 - 0.0018 17.4 0.3 0.0088 15.1 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIY47042.1 - 0.0051 16.8 0.1 0.065 13.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KIY47042.1 - 0.014 14.3 0.4 0.62 8.8 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KIY47042.1 - 0.015 14.0 0.1 0.084 11.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KIY47042.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GMC_oxred_N PF00732.19 KIY47042.1 - 0.039 13.3 0.4 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox PF00070.27 KIY47042.1 - 0.07 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY47042.1 - 0.076 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 KIY47042.1 - 0.11 11.3 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 KIY47042.1 - 0.15 11.3 0.0 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY47042.1 - 0.17 11.0 0.0 0.39 9.8 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amdase PF17645.1 KIY47043.1 - 0.0027 17.4 0.1 0.2 11.3 0.0 2.3 2 1 0 2 2 2 2 Arylmalonate decarboxylase Elong_Iki1 PF10483.9 KIY47044.1 - 7.3e-11 42.1 0.1 2.1e-09 37.3 0.1 2.3 1 1 0 1 1 1 1 Elongator subunit Iki1 Aminotran_1_2 PF00155.21 KIY47045.1 - 1.5e-87 294.1 0.0 1.7e-87 294.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.20 KIY47046.1 - 1.2e-77 261.1 0.0 2e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY47046.1 - 5.8e-09 35.8 0.3 1.1e-08 34.9 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIY47046.1 - 0.044 13.3 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Comm PF15957.5 KIY47047.1 - 0.0041 17.4 0.0 0.0061 16.9 0.0 1.3 1 0 0 1 1 1 1 Commissureless Amnionless PF14828.6 KIY47047.1 - 0.037 12.9 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless SPRY PF00622.28 KIY47048.1 - 2.5e-19 69.5 0.0 4.1e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Collagen_bind_2 PF12904.7 KIY47048.1 - 0.2 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Ac81 PF05820.11 KIY47048.1 - 2.8 7.5 3.8 4.3 6.9 3.8 1.2 1 0 0 1 1 1 0 Baculoviridae AC81 Peptidase_M16_C PF05193.21 KIY47049.1 - 4.1e-14 53.0 0.0 1.4e-08 35.0 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KIY47049.1 - 9.5e-09 35.4 0.0 1.2e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KIY47049.1 - 0.0057 15.8 0.9 0.037 13.1 0.8 2.0 1 1 0 1 1 1 1 Peptidase M16C associated Exo_endo_phos PF03372.23 KIY47050.1 - 1.9e-09 37.4 0.0 4.1e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.20 KIY47051.1 - 3.5e-16 60.0 0.0 6e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Fungal_trans PF04082.18 KIY47052.1 - 1e-09 37.9 0.0 1.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY47052.1 - 1.9e-06 27.9 11.4 4.6e-06 26.6 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0047 PF01894.17 KIY47053.1 - 5.2e-29 100.7 0.0 6.4e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CCCH PF00642.24 KIY47054.1 - 8.1e-18 63.9 25.1 2e-05 24.4 0.6 4.6 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY47054.1 - 3.2e-11 42.9 32.4 9.9e-07 28.6 2.1 4.9 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KIY47054.1 - 7.2e-08 33.1 20.8 0.00031 21.4 0.2 4.6 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 KIY47054.1 - 2.4e-05 24.0 0.4 2.4e-05 24.0 0.4 5.3 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCHC PF00098.23 KIY47054.1 - 0.00012 22.0 5.3 0.00047 20.1 5.3 2.1 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.6 KIY47054.1 - 0.00024 21.5 29.5 0.0082 16.6 0.3 5.2 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCHC_3 PF13917.6 KIY47054.1 - 0.012 15.6 0.2 0.031 14.2 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCCH_3 PF15663.5 KIY47054.1 - 4.8 7.4 16.8 2.5 8.3 0.5 3.7 1 1 3 4 4 4 0 Zinc-finger containing family PDT PF00800.18 KIY47055.1 - 3.4e-43 147.6 0.1 5.1e-41 140.5 0.1 2.1 1 1 0 1 1 1 1 Prephenate dehydratase DUF423 PF04241.15 KIY47056.1 - 7e-14 51.8 0.0 7.9e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ras PF00071.22 KIY47057.1 - 1e-53 181.3 0.0 1.2e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY47057.1 - 3.8e-22 78.7 0.0 5.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY47057.1 - 4.4e-06 26.3 0.0 6.9e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family B277 PF17623.2 KIY47058.1 - 0.69 8.9 1.7 1.5 7.9 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function Fungal_trans PF04082.18 KIY47059.1 - 9.7e-12 44.5 0.3 1.6e-11 43.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1179 PF06678.11 KIY47059.1 - 0.02 14.9 0.8 0.067 13.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Spb1_C PF07780.12 KIY47060.1 - 1.7e-81 272.9 23.0 1.7e-81 272.9 23.0 2.8 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 KIY47060.1 - 1.4e-53 181.6 0.2 3.9e-53 180.2 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KIY47060.1 - 1.6e-45 154.9 8.7 1.6e-45 154.9 8.7 5.1 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) Lar_N PF09861.9 KIY47060.1 - 0.021 14.0 0.3 0.021 14.0 0.3 2.0 2 0 0 2 2 2 0 Lactate racemase N-terminal domain Myb_DNA-bind_6 PF13921.6 KIY47061.1 - 2.8e-24 85.1 0.0 6.2e-13 48.8 0.0 2.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIY47061.1 - 1.3e-23 82.9 1.0 8.7e-13 48.2 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KIY47061.1 - 0.00026 21.1 0.3 0.58 10.4 0.0 2.1 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KIY47061.1 - 0.0012 18.9 0.4 0.45 10.6 0.0 2.1 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 KIY47061.1 - 0.0035 17.3 0.1 0.17 11.9 0.0 2.1 1 1 0 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 KIY47061.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Myb DNA-binding like Bac_small_YrzI PF09501.10 KIY47061.1 - 0.097 12.8 0.2 0.22 11.7 0.1 1.6 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Intron_maturas2 PF01348.21 KIY47061.1 - 0.14 12.1 0.0 5.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Type II intron maturase WD40 PF00400.32 KIY47062.1 - 4.9e-30 103.1 14.4 6.8e-09 36.2 0.5 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY47062.1 - 1.7e-09 37.8 0.1 0.074 13.4 0.0 4.7 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIY47062.1 - 0.00022 19.9 0.0 0.42 9.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.6 KIY47062.1 - 0.015 14.9 0.0 0.086 12.4 0.0 2.1 2 1 0 2 2 2 0 PQQ-like domain InaF-motif PF15018.6 KIY47063.1 - 0.21 11.5 1.3 0.31 10.9 1.3 1.2 1 0 0 1 1 1 0 TRP-interacting helix MCM PF00493.23 KIY47064.1 - 4.8e-97 323.5 0.1 6.9e-97 322.9 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY47064.1 - 3.1e-34 117.6 0.0 5.4e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY47064.1 - 1.9e-22 79.5 2.6 3.6e-22 78.6 2.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIY47064.1 - 6e-15 55.7 0.1 1.7e-14 54.3 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIY47064.1 - 1.3e-07 31.3 0.1 2e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIY47064.1 - 0.0019 18.0 0.0 0.0076 16.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIY47064.1 - 0.0092 16.0 0.3 0.055 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KIY47064.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TGFb_propeptide PF00688.18 KIY47064.1 - 0.049 13.4 0.4 0.083 12.6 0.4 1.3 1 0 0 1 1 1 0 TGF-beta propeptide FAM176 PF14851.6 KIY47064.1 - 0.48 10.1 2.5 0.97 9.1 2.5 1.5 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KIY47064.1 - 0.51 9.6 4.2 0.86 8.9 4.2 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KIY47064.1 - 1.4 9.4 12.8 3.9 7.9 12.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KIY47064.1 - 2.7 8.5 14.5 7.8 7.0 14.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AIM3 PF17096.5 KIY47064.1 - 2.8 8.9 5.3 8.7 7.4 4.6 2.1 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Nbl1_Borealin_N PF10444.9 KIY47065.1 - 2.6e-14 52.6 2.4 5e-14 51.7 2.4 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Abhydrolase_1 PF00561.20 KIY47066.1 - 3.4e-21 76.0 0.0 2.5e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY47066.1 - 6.5e-17 62.9 0.0 9.3e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIY47066.1 - 2.5e-09 37.2 0.1 1.6e-07 31.3 0.1 2.2 1 1 1 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 KIY47066.1 - 6.8e-09 35.3 0.0 1.4e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIY47066.1 - 1.5e-08 35.0 0.0 2.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 KIY47066.1 - 0.00014 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase PF07224.11 KIY47066.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KIY47066.1 - 0.0036 16.3 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 KIY47066.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.18 KIY47066.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Palm_thioest PF02089.15 KIY47066.1 - 0.027 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 KIY47066.1 - 0.029 14.2 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 KIY47066.1 - 0.16 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.20 KIY47066.1 - 0.16 11.6 0.8 0.28 10.8 0.8 1.5 1 1 0 1 1 1 0 Putative esterase RINT1_TIP1 PF04437.13 KIY47067.1 - 1.3e-92 311.3 0.0 2.2e-92 310.5 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family CRAL_TRIO PF00650.20 KIY47068.1 - 3.4e-26 91.9 0.0 6e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY47068.1 - 0.00024 21.2 0.0 0.00049 20.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PRP1_N PF06424.12 KIY47069.1 - 6.8e-50 169.3 3.3 6.8e-50 169.3 3.3 2.5 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KIY47069.1 - 1.1e-27 94.4 30.3 0.0091 16.7 0.0 14.1 4 3 10 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.6 KIY47069.1 - 2.2e-16 60.1 12.1 0.0082 16.6 0.4 7.9 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIY47069.1 - 2.5e-14 53.7 13.3 5.6e-06 26.9 0.0 6.9 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY47069.1 - 1.7e-08 33.9 9.3 0.0069 16.4 0.6 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY47069.1 - 1.6e-07 31.5 6.7 1 10.2 0.0 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY47069.1 - 1.4e-06 27.9 0.3 0.18 11.5 0.0 4.2 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 KIY47069.1 - 2.1e-06 27.3 0.2 0.028 14.2 1.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY47069.1 - 4.2e-06 27.0 2.8 1.4 9.3 0.2 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY47069.1 - 0.00014 21.8 5.6 0.023 14.9 1.5 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 KIY47069.1 - 0.00024 20.9 8.8 0.018 14.7 2.9 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KIY47069.1 - 0.00031 20.8 11.5 0.73 10.0 0.0 5.8 4 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY47069.1 - 0.00033 20.8 1.1 9.8 6.8 0.0 6.7 8 1 0 8 8 7 1 Tetratricopeptide repeat NARP1 PF12569.8 KIY47069.1 - 0.0022 17.0 1.8 2.8 6.8 0.0 4.0 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 FAT PF02259.23 KIY47069.1 - 0.008 15.4 2.7 0.28 10.3 0.1 3.8 3 1 0 3 3 3 1 FAT domain UPF0184 PF03670.13 KIY47069.1 - 0.015 15.6 1.5 0.055 13.9 1.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Suf PF05843.14 KIY47069.1 - 0.043 13.8 0.2 27 4.6 0.0 4.1 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) NT5C PF06941.12 KIY47070.1 - 4.6e-11 42.9 0.1 3.8e-10 39.9 0.1 2.2 1 1 1 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 KIY47070.1 - 8.3e-05 22.7 0.0 0.00029 21.0 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY47070.1 - 0.0021 18.4 0.0 0.018 15.3 0.0 2.2 1 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIY47070.1 - 0.18 12.0 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Cupin_8 PF13621.6 KIY47072.1 - 1.7e-07 31.3 0.4 2.2e-07 30.9 0.4 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KIY47072.1 - 0.0067 16.1 0.1 0.04 13.6 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Transposase_21 PF02992.14 KIY47073.1 - 0.0056 15.9 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Myc_N PF01056.18 KIY47075.1 - 0.034 14.0 0.1 0.043 13.7 0.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TonB_C PF03544.14 KIY47075.1 - 0.12 12.8 0.0 0.44 11.0 0.0 1.9 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal DDE_1 PF03184.19 KIY47076.1 - 3.4e-17 62.7 0.0 6.2e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIY47076.1 - 6.3e-05 22.8 0.1 0.0009 19.0 0.1 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease BIR PF00653.21 KIY47077.1 - 0.014 16.1 0.2 0.037 14.7 0.2 1.8 1 1 0 1 1 1 0 Inhibitor of Apoptosis domain KDZ PF18758.1 KIY47079.1 - 4.7e-40 137.6 0.0 7.2e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF3701 PF12482.8 KIY47079.1 - 0.16 12.0 0.0 0.81 9.8 0.0 2.0 2 0 0 2 2 2 0 Phage integrase protein FTA4 PF13093.6 KIY47079.1 - 0.5 10.2 6.9 4.5 7.1 0.1 2.2 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 KDZ PF18758.1 KIY47080.1 - 1.9e-25 89.8 0.0 2.9e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY47080.1 - 0.019 15.1 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Myb_DNA-binding PF00249.31 KIY47083.1 - 1.7e-19 69.7 0.9 6.2e-10 39.1 0.1 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY47083.1 - 2.5e-16 59.6 0.1 3.3e-07 30.4 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 KIY47083.1 - 1.2e-05 25.3 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 KIY47083.1 - 0.17 12.1 0.6 4.2 7.6 0.0 2.6 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 ABC2_membrane PF01061.24 KIY47084.1 - 2.6e-67 226.3 54.4 4.6e-37 127.5 19.8 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KIY47084.1 - 6.7e-30 104.4 0.0 2.5e-14 54.0 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KIY47084.1 - 1.5e-27 95.3 17.0 3.9e-26 90.8 0.3 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY47084.1 - 2.2e-15 57.0 0.0 5.6e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIY47084.1 - 3.4e-07 30.8 1.2 0.00038 20.9 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIY47084.1 - 8.6e-07 29.3 0.1 0.0091 16.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIY47084.1 - 4e-06 26.8 0.1 0.00021 21.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase dNK PF01712.19 KIY47084.1 - 9.7e-05 22.3 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase NACHT PF05729.12 KIY47084.1 - 0.00074 19.5 0.1 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 KIY47084.1 - 0.00074 19.2 0.3 0.18 11.4 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 KIY47084.1 - 0.0013 17.9 43.3 0.016 14.3 16.5 3.6 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.6 KIY47084.1 - 0.0013 18.3 0.1 0.033 13.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KIY47084.1 - 0.0024 17.9 0.2 0.53 10.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY47084.1 - 0.0041 17.6 0.5 0.29 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY47084.1 - 0.0045 16.7 0.4 0.23 11.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 KIY47084.1 - 0.0046 17.4 0.3 5 7.6 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIY47084.1 - 0.0056 16.4 0.2 0.6 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIY47084.1 - 0.013 14.9 0.0 0.54 9.7 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 KIY47084.1 - 0.017 14.9 0.4 5.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KIY47084.1 - 0.02 14.9 0.4 0.61 10.1 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 KIY47084.1 - 0.02 14.7 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KIY47084.1 - 0.031 14.4 2.5 0.37 10.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.12 KIY47084.1 - 0.044 13.5 0.1 8.3 6.1 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KIY47084.1 - 0.046 13.0 0.1 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 KIY47084.1 - 0.062 13.6 1.0 2 8.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KIY47084.1 - 0.1 13.0 0.4 7.7 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIY47084.1 - 0.16 12.4 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KIY47084.1 - 0.19 11.0 0.2 7 5.8 0.0 2.2 2 0 0 2 2 2 0 Septin ADH_N PF08240.12 KIY47085.1 - 2.5e-28 98.1 1.6 5.2e-28 97.1 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY47085.1 - 1.4e-26 93.0 0.3 2.3e-26 92.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TOBE_2 PF08402.10 KIY47085.1 - 0.048 13.8 0.1 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 TOBE domain ADH_zinc_N_2 PF13602.6 KIY47085.1 - 0.11 13.5 0.0 0.19 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HET PF06985.11 KIY47086.1 - 2.9e-14 53.7 0.2 9.8e-13 48.7 0.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RVT_1 PF00078.27 KIY47089.1 - 7.4e-05 22.4 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIY47090.1 - 0.084 13.6 0.3 0.25 12.1 0.3 1.9 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase PCI PF01399.27 KIY47092.1 - 5.9e-09 36.4 0.0 2e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain Peptidase_M13_N PF05649.13 KIY47093.1 - 5.8e-95 319.2 0.0 7.7e-95 318.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KIY47093.1 - 2.7e-61 206.8 0.0 5.1e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 DUF2716 PF10898.8 KIY47095.1 - 0.0095 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2716) STE3 PF02076.15 KIY47096.1 - 5e-101 337.7 19.8 5.7e-101 337.6 19.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor Rv2175c_C PF18367.1 KIY47097.1 - 0.05 13.7 0.1 0.095 12.8 0.1 1.4 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Dynamin_N PF00350.23 KIY47098.1 - 1.1e-26 93.9 0.0 3.5e-26 92.3 0.0 1.9 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KIY47098.1 - 2.3e-26 92.7 0.0 3.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 KIY47098.1 - 3.3e-12 46.4 0.2 8.3e-12 45.1 0.2 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY47098.1 - 1.3e-05 25.2 0.1 0.00026 21.0 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF4123 PF13503.6 KIY47098.1 - 0.044 14.2 0.2 1.2 9.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) AAA_29 PF13555.6 KIY47098.1 - 0.14 11.9 0.1 0.43 10.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KIY47098.1 - 0.27 11.5 1.8 0.54 10.5 0.3 2.2 2 0 0 2 2 2 0 AAA domain Acetyltransf_3 PF13302.7 KIY47099.1 - 3.1e-15 57.0 0.0 3.8e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY47099.1 - 7.4e-10 39.1 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY47099.1 - 0.0013 19.1 0.0 0.002 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KIY47099.1 - 0.0019 17.8 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.10 KIY47099.1 - 0.042 13.8 0.0 0.44 10.6 0.0 2.1 1 1 0 1 1 1 0 FR47-like protein dCMP_cyt_deam_1 PF00383.23 KIY47100.1 - 1.2e-22 79.6 0.0 1.6e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIY47100.1 - 7.1e-18 64.7 0.0 9.1e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC2 PF18772.1 KIY47100.1 - 0.00014 21.9 0.2 0.0064 16.6 0.2 2.0 1 1 0 1 1 1 1 APOBEC2 Bd3614-deam PF14439.6 KIY47100.1 - 0.00022 21.3 2.6 0.16 12.0 1.0 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase NAD1 PF18778.1 KIY47100.1 - 0.00034 20.8 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 SNAD4 PF18750.1 KIY47100.1 - 0.00041 20.4 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 KIY47100.1 - 0.0019 18.1 0.1 0.007 16.3 0.1 1.8 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD2 PF18782.1 KIY47100.1 - 0.0052 16.9 0.0 0.025 14.7 0.0 1.9 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 KIY47100.1 - 0.036 14.2 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 APOBEC3 XOO_2897-deam PF14440.6 KIY47100.1 - 0.14 12.2 0.2 0.26 11.4 0.0 1.5 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase IBR PF01485.21 KIY47101.1 - 3.8e-11 43.0 32.7 5.5e-08 32.9 9.9 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 KIY47101.1 - 4.3e-07 30.0 5.3 4.3e-07 30.0 5.3 3.8 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIY47101.1 - 1.1e-06 28.4 2.6 1.1e-06 28.4 2.6 4.8 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY47101.1 - 0.00028 20.6 4.3 0.00028 20.6 4.3 4.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY47101.1 - 0.00085 19.3 6.8 0.00085 19.3 6.8 4.0 5 0 0 5 5 5 1 RING-type zinc-finger Pkinase_fungal PF17667.1 KIY47102.1 - 2.4e-21 76.0 0.0 1.2e-14 54.0 0.0 3.1 3 1 0 3 3 3 2 Fungal protein kinase Retrotran_gag_2 PF14223.6 KIY47104.1 - 0.0026 17.4 0.6 0.1 12.3 0.0 2.3 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type RNA_pol_Rpb2_7 PF04560.20 KIY47104.1 - 0.1 13.0 1.5 1 9.8 0.2 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 POT1PC PF16686.5 KIY47106.1 - 0.099 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein DNA_pol_phi PF04931.13 KIY47108.1 - 2.7 6.0 7.2 3.4 5.7 7.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KIY47108.1 - 5.5 5.1 8.8 7 4.7 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family HSP70 PF00012.20 KIY47111.1 - 1e-158 529.3 8.0 5.9e-147 490.4 4.9 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KIY47111.1 - 4.6e-13 48.7 0.9 7.2e-13 48.0 0.9 1.2 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 KIY47111.1 - 0.0057 15.9 1.6 0.3 10.3 0.2 2.3 1 1 1 2 2 2 2 StbA protein Drf_FH3 PF06367.16 KIY47111.1 - 0.02 14.5 0.5 0.033 13.8 0.5 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain DDR PF08841.10 KIY47111.1 - 0.02 13.9 0.4 0.92 8.4 0.2 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KIY47111.1 - 0.022 14.0 0.2 0.09 12.0 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF934 PF06073.12 KIY47111.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF934) RGS12_us2 PF16611.5 KIY47111.1 - 0.15 12.5 0.9 0.32 11.4 0.2 1.8 2 0 0 2 2 2 0 Unstructured region between RBD and GoLoco Retrotran_gag_2 PF14223.6 KIY47113.1 - 7e-11 41.9 0.2 4.2e-07 29.7 0.0 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIY47113.1 - 0.0038 17.0 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIY47113.1 - 0.041 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) HhH-GPD PF00730.25 KIY47115.1 - 5.9e-08 33.1 0.0 7.3e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DDE_Tnp_4 PF13359.6 KIY47116.1 - 1.6e-07 31.1 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4452 PF14618.6 KIY47116.1 - 0.091 12.6 1.7 0.18 11.6 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Hist_deacetyl PF00850.19 KIY47117.1 - 1.1e-45 156.5 0.1 1.5e-45 156.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain APH PF01636.23 KIY47118.1 - 2.5e-06 27.6 0.0 3.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY47118.1 - 0.068 12.5 0.0 5.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.20 KIY47118.1 - 0.076 12.6 0.1 0.21 11.2 0.1 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase HMG_box PF00505.19 KIY47119.1 - 1.2e-09 38.4 2.0 3.1e-07 30.7 1.2 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY47119.1 - 8.5e-07 29.5 6.1 1.8e-05 25.2 3.7 2.5 2 0 0 2 2 2 1 HMG-box domain RR_TM4-6 PF06459.12 KIY47119.1 - 2.7 7.7 5.7 4.7 6.9 5.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GPI-anchored PF10342.9 KIY47122.1 - 0.0019 18.9 0.6 0.0019 18.9 0.6 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1427 PF07235.11 KIY47122.1 - 0.16 12.0 2.1 7.2 6.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) Herpes_capsid PF06112.11 KIY47122.1 - 0.6 10.2 10.6 0.89 9.6 10.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AF-4 PF05110.13 KIY47122.1 - 2.6 6.0 5.3 2.7 5.9 5.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 KIY47122.1 - 3.1 6.0 3.4 3.2 5.9 3.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Alpha-amylase PF00128.24 KIY47124.1 - 6e-18 65.5 0.0 3.5e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain CBM_20 PF00686.19 KIY47124.1 - 4.1e-12 45.9 0.0 1.1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase_C PF02806.18 KIY47124.1 - 1.1e-09 38.6 0.3 4.4e-09 36.7 0.1 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Pkinase PF00069.25 KIY47125.1 - 3e-23 82.6 0.0 3.2e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47125.1 - 1.6e-11 44.0 0.0 1.6e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY47125.1 - 1.7e-06 27.6 0.0 1.8e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY47125.1 - 1.7e-06 27.1 0.0 1.9e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY47125.1 - 7.9e-05 22.7 0.2 0.00011 22.3 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY47125.1 - 0.0098 14.9 0.3 0.013 14.5 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KIY47125.1 - 0.024 14.2 0.3 0.03 13.9 0.3 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIY47125.1 - 0.025 13.9 0.4 0.03 13.7 0.4 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_A4 PF01828.17 KIY47126.1 - 9e-32 110.2 8.0 1.6e-22 80.0 0.9 2.1 1 1 1 2 2 2 2 Peptidase A4 family Pkinase PF00069.25 KIY47127.1 - 5.7e-40 137.3 0.0 1.4e-19 70.5 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47127.1 - 1.8e-16 60.2 0.4 5.8e-05 22.5 0.2 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase DUF3185 PF11381.8 KIY47130.1 - 0.099 12.7 0.2 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Alpha-amylase PF00128.24 KIY47132.1 - 4.4e-18 65.9 0.0 2.6e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain CBM_20 PF00686.19 KIY47132.1 - 1.1e-11 44.5 0.0 2.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase_C PF02806.18 KIY47132.1 - 7.8e-09 35.9 0.2 2.4e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CP_ATPgrasp_1 PF04174.13 KIY47133.1 - 0.14 11.2 0.0 0.29 10.1 0.0 1.4 2 0 0 2 2 2 0 A circularly permuted ATPgrasp KDZ PF18758.1 KIY47135.1 - 1.4e-34 119.7 0.1 1.8e-34 119.3 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIY47136.1 - 1.3e-27 96.9 0.1 1.9e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase HupE_UreJ PF04955.12 KIY47136.1 - 0.22 11.0 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 HupE / UreJ protein Peptidase_A4 PF01828.17 KIY47138.1 - 1.2e-75 253.5 14.7 1.5e-75 253.3 14.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family DBR1 PF05011.13 KIY47139.1 - 4.5e-41 140.5 0.0 1.6e-40 138.7 0.0 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KIY47139.1 - 6.9e-07 30.0 0.1 9.7e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY47139.1 - 0.036 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KIY47139.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Acyltransferase PF01553.21 KIY47140.1 - 1.9e-27 95.5 0.0 2.7e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase PHO4 PF01384.20 KIY47141.1 - 0.084 11.9 3.1 0.1 11.6 3.1 1.1 1 0 0 1 1 1 0 Phosphate transporter family DUF2244 PF10003.9 KIY47141.1 - 1.5 8.5 7.4 1.1 9.0 2.2 2.3 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) STE3 PF02076.15 KIY47142.1 - 6.2e-06 25.6 2.1 1.1e-05 24.8 0.5 1.8 1 1 1 2 2 2 1 Pheromone A receptor Sterol-sensing PF12349.8 KIY47145.1 - 0.96 9.3 3.9 46 3.8 0.0 2.2 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation Plavaka PF18759.1 KIY47149.1 - 1.8e-95 319.9 0.1 2.5e-95 319.4 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase DAGK_cat PF00781.24 KIY47149.1 - 0.045 13.4 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Ribonuc_red_lgC PF02867.15 KIY47150.1 - 2.7e-151 504.7 0.0 2.3e-114 382.8 0.0 2.0 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain IL32 PF15225.6 KIY47152.1 - 0.057 13.8 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Interleukin 32 DUF3446 PF11928.8 KIY47152.1 - 3.8 7.9 20.9 6.3 7.2 15.8 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Barttin PF15462.6 KIY47153.1 - 0.95 9.2 6.1 1.8 8.3 6.1 1.4 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Agenet PF05641.12 KIY47156.1 - 0.15 12.6 0.1 0.36 11.3 0.1 1.6 1 0 0 1 1 1 0 Agenet domain PHO4 PF01384.20 KIY47158.1 - 2 7.4 8.8 1.5 7.8 0.7 2.0 1 1 1 2 2 2 0 Phosphate transporter family F-box-like PF12937.7 KIY47159.1 - 2.7e-06 27.2 4.8 0.00014 21.6 0.0 3.2 2 1 1 3 3 3 2 F-box-like F-box_5 PF18511.1 KIY47159.1 - 0.08 12.5 0.8 0.29 10.8 0.3 2.1 2 0 0 2 2 2 0 F-box PP2C PF00481.21 KIY47160.1 - 2.3e-11 43.8 0.0 2.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PIF1 PF05970.14 KIY47162.1 - 4.6e-06 26.0 0.2 0.0035 16.6 0.0 2.4 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KIY47162.1 - 8e-05 22.4 0.1 0.00039 20.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain SH3_13 PF18335.1 KIY47162.1 - 0.18 11.6 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Cu PF17563.2 KIY47163.1 - 0.12 12.6 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Cupiennin Isochorismatase PF00857.20 KIY47165.1 - 1.4e-18 67.7 0.0 1.1e-17 64.8 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family Ntox27 PF15531.6 KIY47165.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 27 DUF5419 PF17441.2 KIY47167.1 - 0.011 15.8 0.2 0.026 14.6 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5419) DDE_3 PF13358.6 KIY47167.1 - 0.15 11.8 0.0 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 DDE superfamily endonuclease Phage_integrase PF00589.22 KIY47168.1 - 0.0067 16.2 0.0 0.0086 15.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family FAM219A PF15260.6 KIY47169.1 - 0.034 14.5 0.2 0.99 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein family FAM219A Plavaka PF18759.1 KIY47170.1 - 7.9e-31 107.5 0.3 1.1e-30 107.0 0.3 1.1 1 0 0 1 1 1 1 Plavaka transposase PTP_N PF12453.8 KIY47172.1 - 0.016 14.9 0.2 0.028 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Hydrophobin PF01185.18 KIY47173.1 - 5.6e-19 68.5 2.5 7.1e-19 68.2 2.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin F-box-like PF12937.7 KIY47174.1 - 0.00028 20.7 0.6 0.002 18.0 0.6 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY47174.1 - 0.83 9.6 9.3 1.2 9.1 2.0 4.1 4 0 0 4 4 4 0 F-box domain Sugar_tr PF00083.24 KIY47175.1 - 4.8e-88 296.0 20.0 6.1e-88 295.7 20.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY47175.1 - 1.1e-09 37.7 40.0 6.1e-08 32.0 19.8 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4133 PF13571.6 KIY47175.1 - 0.13 12.6 0.2 0.13 12.6 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4133) TIP120 PF08623.10 KIY47176.1 - 2.2e-56 190.2 1.4 5.5e-56 188.9 0.2 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KIY47176.1 - 7.3e-10 39.1 16.7 0.048 14.1 0.3 8.8 8 1 1 9 9 9 3 HEAT repeats HEAT PF02985.22 KIY47176.1 - 7.7e-10 38.2 27.1 0.92 9.9 0.1 11.1 11 0 0 11 11 10 3 HEAT repeat Tti2 PF10521.9 KIY47176.1 - 2.1e-08 34.1 8.4 0.00017 21.2 0.0 4.8 4 1 1 5 5 4 1 Tti2 family HEAT_EZ PF13513.6 KIY47176.1 - 8.1e-08 32.6 24.0 0.00014 22.3 0.4 9.5 8 3 2 11 11 10 2 HEAT-like repeat Adaptin_N PF01602.20 KIY47176.1 - 3.5e-05 22.6 5.8 1.1 7.7 0.1 5.9 5 2 1 7 7 7 2 Adaptin N terminal region CLASP_N PF12348.8 KIY47176.1 - 4.4e-05 23.2 2.0 0.2 11.2 0.2 4.7 5 0 0 5 5 5 1 CLASP N terminal DUF3385 PF11865.8 KIY47176.1 - 0.0001 22.3 0.4 0.23 11.4 0.0 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KIY47176.1 - 0.00011 22.2 8.5 0.11 12.5 0.1 6.3 7 2 1 8 8 8 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KIY47176.1 - 0.002 17.3 18.3 0.02 14.0 0.3 5.7 6 0 0 6 6 6 2 RNAPII transcription regulator C-terminal DUF4042 PF13251.6 KIY47176.1 - 0.0028 17.4 1.3 33 4.1 0.1 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) RTP1_C1 PF10363.9 KIY47176.1 - 0.031 14.5 3.0 0.33 11.1 0.1 3.7 5 0 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF2779 PF11074.8 KIY47176.1 - 0.073 13.5 0.1 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) UME PF08064.13 KIY47176.1 - 0.092 12.7 0.5 6.6 6.7 0.0 4.0 4 1 0 4 4 4 0 UME (NUC010) domain API5 PF05918.11 KIY47176.1 - 0.15 10.9 0.7 3.4 6.4 0.1 2.7 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) GARP PF16731.5 KIY47176.1 - 0.24 11.1 2.7 0.8 9.4 0.4 2.5 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Sigma70_ner PF04546.13 KIY47176.1 - 0.26 11.2 4.3 0.19 11.6 1.9 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region ParcG PF10274.9 KIY47176.1 - 0.26 11.4 0.0 0.26 11.4 0.0 4.4 6 0 0 6 6 5 0 Parkin co-regulated protein RRN3 PF05327.11 KIY47176.1 - 0.38 9.2 3.3 0.36 9.3 1.4 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 KIY47176.1 - 1.3 8.7 3.3 2.9 7.6 1.9 2.1 2 0 0 2 2 2 0 FAM176 family TRAP_alpha PF03896.16 KIY47176.1 - 1.4 8.1 4.7 5.2 6.2 2.6 2.6 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid_p PF12226.8 KIY47176.1 - 9.6 5.3 9.5 17 4.4 9.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ABC2_membrane PF01061.24 KIY47177.1 - 2e-76 256.1 57.9 1.1e-40 139.4 18.8 3.1 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KIY47177.1 - 6.3e-34 115.8 11.1 8.4e-29 99.3 0.1 2.9 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KIY47177.1 - 1e-25 90.8 0.0 7.1e-15 55.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KIY47177.1 - 4e-13 49.8 0.1 1e-12 48.5 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIY47177.1 - 1.1e-06 29.1 0.1 0.0036 17.7 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY47177.1 - 5.5e-06 26.4 0.1 4.9e-05 23.3 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIY47177.1 - 0.00019 21.7 0.1 0.1 12.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KIY47177.1 - 0.0064 16.1 0.4 0.025 14.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIY47177.1 - 0.0067 16.3 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KIY47177.1 - 0.0068 16.3 0.0 0.12 12.3 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.6 KIY47177.1 - 0.0098 16.4 0.0 0.72 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIY47177.1 - 0.026 14.0 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KIY47177.1 - 0.035 14.3 0.2 2.7 8.2 0.1 2.9 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 KIY47177.1 - 0.042 13.9 0.0 0.84 9.7 0.1 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase dNK PF01712.19 KIY47177.1 - 0.053 13.4 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.17 KIY47177.1 - 0.055 13.5 0.1 0.48 10.4 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KIY47177.1 - 0.07 12.7 0.4 1.7 8.2 0.2 2.5 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KIY47177.1 - 0.072 12.8 0.0 0.7 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIY47177.1 - 0.073 12.8 0.3 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 KIY47177.1 - 0.084 13.3 0.0 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3464 PF11947.8 KIY47177.1 - 0.098 12.4 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AAA_23 PF13476.6 KIY47177.1 - 0.18 12.3 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 KIY47177.1 - 0.2 10.9 10.7 0.039 13.2 6.4 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC_ATPase PF09818.9 KIY47177.1 - 0.22 10.3 0.1 0.38 9.5 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class ABC2_membrane_3 PF12698.7 KIY47177.1 - 6.1 5.8 53.4 2.1 7.4 25.7 4.1 2 2 1 3 3 3 0 ABC-2 family transporter protein UDPGT PF00201.18 KIY47179.1 - 2.7e-09 36.3 0.1 2.9e-09 36.3 0.1 1.2 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase K_oxygenase PF13434.6 KIY47180.1 - 1.4e-12 47.4 0.0 5.8e-10 38.8 0.0 2.8 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIY47180.1 - 1.3e-11 44.7 1.2 0.012 15.3 1.0 4.2 3 1 0 4 4 4 4 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY47180.1 - 2.2e-11 43.6 0.0 1.4e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIY47180.1 - 4.5e-11 41.9 0.0 5.9e-10 38.2 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KIY47180.1 - 7.8e-09 35.6 0.2 2.3e-05 24.5 0.1 3.3 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY47180.1 - 1.4e-08 34.4 0.1 0.0097 15.2 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY47180.1 - 7.1e-08 32.6 0.6 0.055 13.4 0.6 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIY47180.1 - 1e-05 24.9 0.7 0.1 11.7 0.2 3.4 4 0 0 4 4 4 2 FAD binding domain Pyr_redox PF00070.27 KIY47180.1 - 1.4e-05 25.5 0.1 0.02 15.4 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY47180.1 - 2.7e-05 23.6 1.4 0.057 12.7 0.0 2.7 3 0 0 3 3 3 2 Thi4 family HI0933_like PF03486.14 KIY47180.1 - 0.00012 20.9 1.2 0.38 9.4 0.4 3.7 4 0 0 4 4 4 1 HI0933-like protein Shikimate_DH PF01488.20 KIY47180.1 - 0.00014 21.9 0.1 0.066 13.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KIY47180.1 - 0.0011 18.3 0.5 0.0043 16.3 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KIY47180.1 - 0.0072 15.7 0.1 7.7 5.7 0.0 3.6 3 1 1 4 4 4 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIY47180.1 - 0.012 14.7 0.5 1.6 7.7 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein ApbA PF02558.16 KIY47180.1 - 0.028 14.1 0.4 0.084 12.5 0.4 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Mqo PF06039.15 KIY47180.1 - 0.03 12.9 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_7 PF13241.6 KIY47180.1 - 0.047 14.1 0.0 5.6 7.5 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 KIY47180.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 KIY47180.1 - 0.25 11.6 0.4 14 6.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 KIY47180.1 - 0.25 10.4 0.2 12 4.8 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KIY47180.1 - 0.25 11.2 0.2 13 5.6 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase PF05221.17 KIY47181.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase DUF3944 PF13099.6 KIY47181.1 - 0.15 11.9 0.0 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) BTB PF00651.31 KIY47182.1 - 1.2e-09 38.3 0.0 1.5e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Homeobox_KN PF05920.11 KIY47183.1 - 2.1e-16 59.6 0.0 3.7e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KIY47183.1 - 0.0097 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain BTB PF00651.31 KIY47184.1 - 5.7e-08 33.0 0.0 8.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Abhydrolase_6 PF12697.7 KIY47185.1 - 1.6e-09 38.7 0.2 2.1e-09 38.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Filaggrin PF03516.13 KIY47186.1 - 2.4 8.9 5.1 40 5.0 1.1 2.8 2 0 0 2 2 2 0 Filaggrin Complex1_51K PF01512.17 KIY47187.1 - 5.2e-48 162.8 0.0 7.9e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KIY47187.1 - 8e-31 106.0 1.3 1.5e-30 105.0 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KIY47187.1 - 1.9e-07 30.8 0.0 4.6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 SLBB domain K_oxygenase PF13434.6 KIY47188.1 - 8.8e-12 44.8 0.0 3.6e-09 36.2 0.0 2.8 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIY47188.1 - 2.5e-10 40.1 0.0 6.9e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY47188.1 - 1.8e-09 37.6 4.2 0.014 15.0 1.1 4.2 3 1 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIY47188.1 - 8.9e-09 35.0 0.0 0.006 15.9 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIY47188.1 - 5.9e-08 31.6 0.0 1.4e-06 27.1 0.0 2.5 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KIY47188.1 - 6e-08 32.8 2.6 0.017 15.1 0.4 4.1 2 2 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIY47188.1 - 7.9e-08 32.4 0.2 2.2e-05 24.6 0.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY47188.1 - 2.2e-05 23.8 2.3 0.076 12.1 0.2 3.2 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 KIY47188.1 - 2.4e-05 23.7 0.7 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KIY47188.1 - 3.3e-05 24.3 1.1 0.04 14.5 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIY47188.1 - 0.00012 21.6 0.4 1.8 7.7 0.0 3.9 3 1 1 4 4 4 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 KIY47188.1 - 0.00016 21.7 0.0 0.042 13.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KIY47188.1 - 0.00019 20.3 2.4 0.73 8.5 0.4 3.6 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.19 KIY47188.1 - 0.00085 18.7 0.7 0.0056 16.0 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KIY47188.1 - 0.018 14.1 0.7 0.63 9.0 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Mqo PF06039.15 KIY47188.1 - 0.026 13.1 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) ApbA PF02558.16 KIY47188.1 - 0.027 14.1 0.3 0.059 13.0 0.3 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KIY47188.1 - 0.048 14.1 0.0 4.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 KIY47188.1 - 0.096 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus RVT_1 PF00078.27 KIY47190.1 - 5.7e-06 26.0 0.0 1.4e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SnoaL_2 PF12680.7 KIY47190.1 - 0.024 15.3 0.0 0.1 13.2 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like domain FAM176 PF14851.6 KIY47192.1 - 0.022 14.4 5.8 0.062 13.0 5.2 1.9 2 0 0 2 2 2 0 FAM176 family PAT1 PF09770.9 KIY47192.1 - 0.21 9.8 2.7 0.25 9.6 2.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 KIY47192.1 - 0.34 10.9 0.9 0.45 10.5 0.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Bombinin PF05298.11 KIY47192.1 - 0.51 10.0 3.1 0.78 9.4 3.1 1.2 1 0 0 1 1 1 0 Bombinin AAA PF00004.29 KIY47195.1 - 5.4e-39 133.6 0.0 8.4e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY47195.1 - 1.3e-10 40.9 0.0 2.5e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KIY47195.1 - 4.3e-07 29.8 0.0 8.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIY47195.1 - 8.2e-07 29.6 0.1 2.4e-05 24.8 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KIY47195.1 - 1.4e-05 25.2 0.0 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIY47195.1 - 2.8e-05 24.1 0.2 0.00061 19.8 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY47195.1 - 0.00015 21.9 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KIY47195.1 - 0.00025 21.6 0.0 0.00046 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIY47195.1 - 0.00033 20.1 0.2 0.0014 18.0 0.2 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KIY47195.1 - 0.00049 20.3 0.0 0.0008 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KIY47195.1 - 0.0005 19.5 0.0 1.7 8.0 0.0 3.1 2 1 1 3 3 3 1 Bacterial TniB protein AAA_22 PF13401.6 KIY47195.1 - 0.00054 20.3 0.1 0.0056 17.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 KIY47195.1 - 0.00097 19.1 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 KIY47195.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KIY47195.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Hydin_ADK PF17213.3 KIY47195.1 - 0.0016 18.8 0.1 0.12 12.6 0.1 2.2 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain TIP49 PF06068.13 KIY47195.1 - 0.0021 17.3 0.1 0.0033 16.7 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 KIY47195.1 - 0.0022 17.8 0.0 0.0039 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KIY47195.1 - 0.0042 17.0 0.2 0.018 15.0 0.1 2.1 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 KIY47195.1 - 0.0052 16.3 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KIY47195.1 - 0.0073 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 KIY47195.1 - 0.0088 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIY47195.1 - 0.0098 15.2 0.1 0.019 14.2 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 KIY47195.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 KIY47195.1 - 0.015 14.9 0.5 0.097 12.2 0.2 2.3 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.21 KIY47195.1 - 0.016 14.9 0.0 1.7 8.3 0.0 2.6 2 1 0 2 2 2 0 Guanylate kinase AAA_17 PF13207.6 KIY47195.1 - 0.022 15.2 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIY47195.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KIY47195.1 - 0.025 14.4 0.0 0.17 11.7 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein Viral_helicase1 PF01443.18 KIY47195.1 - 0.036 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KIY47195.1 - 0.041 13.0 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KIY47195.1 - 0.043 12.9 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KIY47195.1 - 0.046 14.2 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KIY47195.1 - 0.051 13.5 0.0 0.16 11.8 0.0 1.7 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KIY47195.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KIY47195.1 - 0.16 11.3 0.0 1.3 8.3 0.0 2.0 1 1 1 2 2 2 0 KaiC GTP_EFTU PF00009.27 KIY47196.1 - 4.2e-66 222.2 0.1 7e-66 221.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIY47196.1 - 2.2e-34 117.8 0.0 1.5e-33 115.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KIY47196.1 - 1.5e-22 79.4 0.0 3.4e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KIY47196.1 - 8.6e-13 48.2 0.0 2.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KIY47196.1 - 2.1e-12 47.3 0.0 6.2e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY47196.1 - 0.0012 19.0 0.1 0.003 17.6 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Phosphoesterase PF04185.14 KIY47198.1 - 1.2e-29 103.7 1.8 2.5e-28 99.3 1.8 2.0 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 KIY47198.1 - 0.0043 16.5 0.1 0.007 15.8 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Dicty_REP PF05086.12 KIY47198.1 - 0.17 9.8 0.3 0.24 9.3 0.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein p450 PF00067.22 KIY47199.1 - 5.5e-59 200.1 0.0 7e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CoaE PF01121.20 KIY47201.1 - 2.2e-64 216.4 0.0 2.7e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KIY47201.1 - 0.00078 20.0 0.2 0.01 16.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KIY47201.1 - 0.0019 18.0 0.2 1 9.1 0.1 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KIY47201.1 - 0.028 14.6 0.0 0.089 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIY47201.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain p450 PF00067.22 KIY47202.1 - 1.1e-60 205.7 0.0 5e-60 203.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KIY47204.1 - 7.1e-14 51.8 0.1 9.2e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KIY47204.1 - 5.6e-06 25.5 0.1 0.0039 16.1 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KIY47204.1 - 6.3e-05 23.0 0.1 0.036 14.0 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIY47204.1 - 0.0012 19.0 0.1 0.0032 17.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIY47204.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KIY47204.1 - 0.015 14.5 0.2 0.16 11.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY47204.1 - 0.03 13.6 0.8 1.2 8.3 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY47204.1 - 0.031 13.0 0.1 0.18 10.5 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Pkinase PF00069.25 KIY47206.1 - 1.4e-06 27.9 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47206.1 - 6.5e-05 22.3 0.0 9.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY47206.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KIY47206.1 - 0.11 11.8 0.2 0.15 11.3 0.2 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Abhydrolase_1 PF00561.20 KIY47207.1 - 2.5e-16 60.1 0.0 1.3e-09 38.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY47207.1 - 8e-12 46.2 2.0 1.1e-11 45.8 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY47207.1 - 7.8e-11 41.7 0.0 0.00033 20.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIY47207.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 KIY47207.1 - 0.03 13.0 0.0 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 Ndr family Retrotrans_gag PF03732.17 KIY47208.1 - 6.5e-06 26.3 0.9 1.1e-05 25.6 0.5 1.7 1 1 1 2 2 2 1 Retrotransposon gag protein PSP1 PF04468.12 KIY47209.1 - 2.1e-32 111.2 1.0 3.1e-32 110.7 1.0 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region adh_short PF00106.25 KIY47210.1 - 8.7e-24 84.1 0.8 1.1e-22 80.5 0.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY47210.1 - 4.5e-12 46.0 2.2 5.8e-08 32.6 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY47210.1 - 0.00011 22.2 0.3 0.00011 22.2 0.3 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY47210.1 - 0.0045 16.5 0.1 1.9 7.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 KIY47211.1 - 0.0016 18.3 3.1 0.002 18.0 1.8 1.9 2 0 0 2 2 2 1 F-box-like HAD_2 PF13419.6 KIY47212.1 - 1.8e-14 54.3 0.0 2.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY47212.1 - 4.6e-07 30.3 0.0 0.00022 21.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY47212.1 - 0.00048 20.1 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ntox35 PF15534.6 KIY47212.1 - 0.2 12.1 0.0 0.35 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 35 SusD-like PF12741.7 KIY47214.1 - 0.08 11.8 0.3 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein TypeIII_RM_meth PF12564.8 KIY47215.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit BTB PF00651.31 KIY47220.1 - 0.0012 19.1 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Fasciclin PF02469.22 KIY47221.1 - 0.019 15.2 0.1 0.024 14.9 0.1 1.2 1 1 0 1 1 1 0 Fasciclin domain SnoaL_2 PF12680.7 KIY47224.1 - 2e-05 25.2 0.1 2.6e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 KIY47224.1 - 0.0038 17.3 0.0 0.01 16.0 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIY47224.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) EIIA-man PF03610.16 KIY47224.1 - 0.069 13.4 0.0 0.091 13.0 0.0 1.1 1 0 0 1 1 1 0 PTS system fructose IIA component BNR_4 PF15892.5 KIY47225.1 - 2.6e-60 204.1 2.1 1.1e-59 202.0 2.1 1.9 1 1 0 1 1 1 1 BNR repeat-containing family member F-box-like PF12937.7 KIY47226.1 - 0.00023 21.0 0.1 0.0006 19.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY47226.1 - 0.019 14.9 2.2 0.19 11.6 2.2 2.7 1 1 0 1 1 1 0 F-box domain Melittin PF01372.17 KIY47226.1 - 0.16 12.0 0.3 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Melittin Tim29 PF10171.9 KIY47227.1 - 0.058 12.9 0.2 0.092 12.2 0.2 1.3 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 NAD_binding_8 PF13450.6 KIY47228.1 - 3.5e-10 40.0 0.0 5.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY47228.1 - 7.5e-06 25.4 0.0 8.9e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY47228.1 - 1.4e-05 24.5 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KIY47228.1 - 1.7e-05 24.3 0.0 2.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KIY47228.1 - 2.7e-05 23.5 0.0 3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY47228.1 - 5.1e-05 22.7 0.0 6.2e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY47228.1 - 0.00021 20.1 0.0 0.00026 19.8 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KIY47228.1 - 0.0028 16.9 0.0 0.0031 16.8 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIY47228.1 - 0.0029 17.3 0.0 0.0035 17.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIY47228.1 - 0.0064 15.9 0.0 0.0075 15.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KIY47228.1 - 0.0087 16.3 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.27 KIY47228.1 - 0.018 15.6 0.0 0.021 15.4 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY47228.1 - 0.039 13.0 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIY47228.1 - 0.086 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.16 KIY47228.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KIY47228.1 - 0.17 11.3 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTD PF01993.18 KIY47228.1 - 0.2 11.0 0.0 0.21 10.9 0.0 1.0 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Shikimate_DH PF01488.20 KIY47228.1 - 0.26 11.4 0.0 0.33 11.0 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-RVT PF13966.6 KIY47229.1 - 7.3e-09 36.2 2.8 2.1e-08 34.7 0.3 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Rrp44_CSD1 PF17216.3 KIY47230.1 - 1.7 8.3 3.4 1.5 8.5 2.4 1.4 1 1 0 1 1 1 0 Rrp44-like cold shock domain SPG48 PF14764.6 KIY47233.1 - 0.068 13.6 0.1 0.098 13.1 0.1 1.4 1 1 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking Oxidored_q3 PF00499.20 KIY47234.1 - 1.9e-31 108.7 27.0 2.5e-31 108.4 27.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 A_deamin PF02137.18 KIY47235.1 - 1.9e-25 90.1 0.0 2.2e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain zf-CCHC_2 PF13696.6 KIY47236.1 - 0.001 18.8 3.0 0.0018 18.0 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY47236.1 - 0.0019 18.2 6.1 0.0032 17.5 6.1 1.4 1 0 0 1 1 1 1 Zinc knuckle SF3a60_bindingd PF12108.8 KIY47236.1 - 0.084 12.8 0.6 0.15 12.0 0.6 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain AAA PF00004.29 KIY47237.1 - 5.9e-60 201.5 0.0 8.6e-42 142.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY47237.1 - 2.2e-13 50.9 0.8 8.7e-08 32.7 0.6 3.4 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KIY47237.1 - 1.4e-11 44.4 0.0 4.7e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY47237.1 - 2.2e-11 43.9 0.1 7e-07 29.3 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY47237.1 - 2.4e-09 37.6 0.1 3.5e-05 24.1 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY47237.1 - 1.4e-08 35.0 0.0 0.0001 22.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KIY47237.1 - 6.2e-08 32.3 0.3 1.6e-07 31.0 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KIY47237.1 - 1.1e-07 31.8 0.0 0.00019 21.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 KIY47237.1 - 1.5e-07 30.9 0.0 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain TsaE PF02367.17 KIY47237.1 - 3.4e-06 27.1 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KIY47237.1 - 3.8e-05 23.2 0.3 0.078 12.3 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KIY47237.1 - 4.3e-05 23.5 0.0 0.0098 15.8 0.0 3.0 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 KIY47237.1 - 4.3e-05 23.8 0.0 0.024 15.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 KIY47237.1 - 7.6e-05 22.1 0.0 0.012 14.9 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin AAA_28 PF13521.6 KIY47237.1 - 0.00011 22.5 0.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY47237.1 - 0.00015 21.4 0.6 0.18 11.4 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KIY47237.1 - 0.00018 21.4 0.0 0.0047 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KIY47237.1 - 0.00019 21.6 0.0 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 KIY47237.1 - 0.0011 18.8 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIY47237.1 - 0.0012 19.4 0.0 0.013 16.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain DAP3 PF10236.9 KIY47237.1 - 0.0016 17.7 0.0 0.007 15.6 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 KIY47237.1 - 0.0017 17.9 0.0 0.47 9.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KIY47237.1 - 0.0021 17.8 0.0 0.017 14.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 KIY47237.1 - 0.0021 17.3 0.0 0.26 10.4 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KIY47237.1 - 0.0022 17.1 0.0 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Rad17 PF03215.15 KIY47237.1 - 0.0025 17.8 0.0 0.49 10.3 0.0 2.8 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 KIY47237.1 - 0.0031 17.3 0.0 0.051 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIY47237.1 - 0.005 16.8 0.0 22 4.9 0.0 3.2 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KIY47237.1 - 0.0053 16.1 0.0 2.8 7.2 0.0 2.4 2 0 0 2 2 2 1 KaiC Viral_helicase1 PF01443.18 KIY47237.1 - 0.0062 16.3 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KIY47237.1 - 0.009 15.5 0.1 0.67 9.4 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 KIY47237.1 - 0.013 15.6 0.0 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KIY47237.1 - 0.014 15.1 0.0 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 KIY47237.1 - 0.015 15.8 0.0 0.8 10.2 0.0 3.0 2 1 1 3 3 3 0 ABC transporter Bac_DnaA PF00308.18 KIY47237.1 - 0.027 14.3 0.0 0.21 11.4 0.0 2.2 3 0 0 3 3 3 0 Bacterial dnaA protein NTPase_1 PF03266.15 KIY47237.1 - 0.029 14.3 0.0 0.28 11.1 0.0 2.3 2 1 0 2 2 2 0 NTPase AAA_19 PF13245.6 KIY47237.1 - 0.031 14.6 0.1 0.46 10.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain AFG1_ATPase PF03969.16 KIY47237.1 - 0.073 12.0 0.0 0.76 8.6 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase NB-ARC PF00931.22 KIY47237.1 - 0.086 12.0 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_6 PF12774.7 KIY47237.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DUF2075 PF09848.9 KIY47237.1 - 0.21 10.8 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pkinase PF00069.25 KIY47238.1 - 1.3e-20 73.9 0.1 1.4e-20 73.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47238.1 - 4.2e-11 42.6 0.0 4.4e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY47238.1 - 3.9e-06 26.4 0.0 4.1e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY47238.1 - 2e-05 23.6 0.1 2.1e-05 23.5 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY47238.1 - 0.00062 19.8 0.3 0.00081 19.4 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY47238.1 - 0.02 13.8 0.2 0.025 13.5 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KIY47238.1 - 0.18 11.4 0.6 0.23 11.0 0.6 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIY47238.1 - 0.23 10.8 0.3 0.27 10.6 0.3 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ERp29 PF07749.12 KIY47240.1 - 0.0083 17.0 1.7 0.012 16.5 1.3 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain DUF2315 PF10231.9 KIY47240.1 - 0.038 14.1 4.3 0.057 13.5 4.3 1.3 1 0 0 1 1 1 0 Apoptogenic protein 1 DegT_DnrJ_EryC1 PF01041.17 KIY47240.1 - 0.081 12.2 1.0 0.1 11.9 1.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IL33 PF15095.6 KIY47240.1 - 0.93 8.9 6.0 1.5 8.2 6.0 1.3 1 0 0 1 1 1 0 Interleukin 33 DUF4355 PF14265.6 KIY47240.1 - 2.1 8.6 10.3 2.3 8.5 9.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) Orthopox_A5L PF06193.11 KIY47241.1 - 0.0067 15.9 0.5 0.0093 15.4 0.5 1.2 1 0 0 1 1 1 1 Orthopoxvirus A5L protein-like TolA_bind_tri PF16331.5 KIY47241.1 - 0.13 12.4 4.5 0.21 11.7 4.5 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF4924 PF16271.5 KIY47241.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) GIT_CC PF16559.5 KIY47241.1 - 0.57 10.1 6.7 0.93 9.4 6.7 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Peptidase_C48 PF02902.19 KIY47242.1 - 1e-10 41.8 0.4 1.6e-10 41.2 0.4 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ribosomal_L31e PF01198.19 KIY47244.1 - 3.8e-37 126.4 1.1 5.4e-37 125.9 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e GCS2 PF04107.13 KIY47245.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Helicase_C PF00271.31 KIY47250.1 - 0.0092 16.3 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase_fungal PF17667.1 KIY47251.1 - 3.4e-10 39.3 0.0 3.9e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase OrsD PF12013.8 KIY47252.1 - 0.0067 16.9 3.5 0.021 15.3 3.3 1.9 1 1 1 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 KIY47253.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1319 PF07028.11 KIY47253.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) TEA PF01285.18 KIY47254.1 - 2.8e-09 36.9 0.0 6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Phasin_2 PF09361.10 KIY47255.1 - 0.029 14.6 4.4 0.029 14.6 4.4 1.8 2 0 0 2 2 2 0 Phasin protein SKG6 PF08693.10 KIY47258.1 - 0.0068 15.8 0.6 0.0068 15.8 0.6 2.5 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Syndecan PF01034.20 KIY47258.1 - 0.26 11.2 0.1 0.44 10.5 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Amnionless PF14828.6 KIY47258.1 - 0.32 9.8 7.4 0.54 9.0 0.0 2.0 1 1 1 2 2 2 0 Amnionless TrbL PF04610.14 KIY47258.1 - 8.1 6.1 7.5 0.66 9.7 1.7 1.9 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein E1-E2_ATPase PF00122.20 KIY47259.1 - 0.03 13.9 1.2 0.99 8.9 0.0 2.1 1 1 1 2 2 2 0 E1-E2 ATPase Syndecan PF01034.20 KIY47259.1 - 0.14 12.0 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain SOG2 PF10428.9 KIY47259.1 - 0.3 10.3 17.1 0.36 10.0 17.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4023 PF13215.6 KIY47260.1 - 8.2 6.5 9.5 2.3 8.3 3.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) KDZ PF18758.1 KIY47261.1 - 2.8e-22 79.4 4.4 3.1e-22 79.3 4.4 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase NEL PF14496.6 KIY47262.1 - 0.072 12.5 0.8 0.34 10.3 0.2 1.9 1 1 1 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting Exo_endo_phos PF03372.23 KIY47263.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CHD5 PF04420.14 KIY47265.1 - 3.7e-51 173.1 0.4 4.4e-51 172.9 0.4 1.1 1 0 0 1 1 1 1 CHD5-like protein ABC_membrane_3 PF13748.6 KIY47265.1 - 0.089 12.0 0.6 0.12 11.6 0.6 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF1514 PF07438.11 KIY47265.1 - 2.7 7.9 5.2 39 4.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1514) Malate_synthase PF01274.22 KIY47266.1 - 2.4e-198 659.7 0.0 2.9e-198 659.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase FKBP_C PF00254.28 KIY47267.1 - 2.4e-26 91.9 0.0 3.2e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MRP-L27 PF09809.9 KIY47267.1 - 0.18 11.7 0.0 4.7 7.1 0.0 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L27 Polysacc_deac_1 PF01522.21 KIY47268.1 - 5.2e-32 110.3 0.0 2.8e-31 108.0 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KIY47268.1 - 0.022 14.0 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DASH_Dad2 PF08654.10 KIY47268.1 - 0.18 12.2 0.1 0.35 11.3 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 adh_short PF00106.25 KIY47269.1 - 3.4e-12 46.2 0.1 3.3e-11 43.0 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY47269.1 - 7.5e-10 38.8 0.0 1.5e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY47269.1 - 0.0019 18.1 0.2 0.0094 15.9 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY47269.1 - 0.023 14.1 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PALP PF00291.25 KIY47269.1 - 0.05 13.0 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme UDPG_MGDP_dh_N PF03721.14 KIY47269.1 - 0.12 11.9 0.0 14 5.2 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DFP PF04127.15 KIY47269.1 - 0.23 11.3 0.1 0.37 10.6 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pkinase PF00069.25 KIY47270.1 - 8.8e-63 212.1 0.2 1e-61 208.6 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47270.1 - 5e-40 137.4 0.0 1.8e-24 86.4 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY47270.1 - 3.5e-05 23.3 0.4 8.2e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Hypoth_Ymh PF09509.10 KIY47270.1 - 0.0065 16.4 3.2 0.017 15.0 3.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (Hypoth_ymh) APH PF01636.23 KIY47270.1 - 0.014 15.3 0.2 0.014 15.3 0.2 3.3 2 2 1 3 3 3 0 Phosphotransferase enzyme family Dot_icm_IcmQ PF09475.10 KIY47270.1 - 0.073 12.6 9.7 0.035 13.6 6.7 1.9 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) DUF3573 PF12097.8 KIY47270.1 - 1.1 8.0 3.9 1.7 7.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) M_domain PF12938.7 KIY47270.1 - 3.7 7.3 16.9 6.3 6.5 16.9 1.3 1 0 0 1 1 1 0 M domain of GW182 Muskelin_N PF06588.11 KIY47271.1 - 1.1e-57 195.1 0.1 4.1e-56 190.1 0.0 2.3 2 0 0 2 2 2 1 Muskelin N-terminus Kelch_4 PF13418.6 KIY47271.1 - 3e-28 97.6 1.0 4.9e-08 32.9 0.0 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KIY47271.1 - 1.2e-26 92.4 8.4 6.4e-08 32.7 0.0 7.6 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KIY47271.1 - 7.5e-22 76.9 0.4 2.1e-05 24.4 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KIY47271.1 - 2.8e-14 52.8 0.0 0.0074 16.5 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KIY47271.1 - 1.5e-12 46.9 0.2 0.00015 21.3 0.0 5.8 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KIY47271.1 - 1.6e-05 24.7 2.1 0.034 14.1 0.0 5.2 5 1 0 5 5 5 1 Kelch motif F5_F8_type_C PF00754.25 KIY47271.1 - 0.00061 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 KIY47271.1 - 0.0099 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 XRCC1 N terminal domain MDD_C PF18376.1 KIY47272.1 - 2.7e-72 242.5 0.1 3.5e-72 242.1 0.1 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KIY47272.1 - 1.5e-05 25.1 5.7 3.1e-05 24.1 5.7 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain ketoacyl-synt PF00109.26 KIY47273.1 - 4.4e-66 223.0 0.6 3.5e-65 220.1 0.6 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIY47273.1 - 1.4e-49 169.3 0.0 2.8e-48 165.1 0.0 2.7 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KIY47273.1 - 9.5e-37 125.6 0.8 1.8e-36 124.7 0.8 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KIY47273.1 - 3.9e-21 75.9 0.4 5.1e-18 65.7 0.2 2.6 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 KIY47273.1 - 6.1e-17 62.5 0.0 6.2e-16 59.2 0.0 2.5 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 KIY47273.1 - 3.1e-14 52.9 0.1 7.5e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KIY47273.1 - 1.4e-08 35.0 0.1 4.7e-08 33.3 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KIY47273.1 - 9.2e-07 29.7 1.0 9.2e-07 29.7 1.0 3.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KIY47273.1 - 1e-05 25.9 0.0 2.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KIY47273.1 - 1.8e-05 24.2 0.2 3.8e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.8 KIY47273.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S8 PF00082.22 KIY47274.1 - 6.4e-50 170.1 5.6 1.1e-49 169.4 5.6 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KIY47274.1 - 1.9e-08 35.0 0.2 4.2e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KIY47274.1 - 4.3e-05 23.5 1.0 0.0001 22.2 0.1 2.1 2 0 0 2 2 2 1 PA domain RPT PF13446.6 KIY47274.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Prefoldin_2 PF01920.20 KIY47275.1 - 9.3e-23 80.2 4.1 1.2e-22 79.9 4.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KIY47275.1 - 0.0013 18.6 6.6 0.16 11.9 0.4 2.1 1 1 1 2 2 2 2 Prefoldin subunit DUF948 PF06103.11 KIY47275.1 - 0.0039 17.4 0.5 1.4 9.2 0.1 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) APP_E2 PF12925.7 KIY47275.1 - 0.0092 15.7 0.7 0.013 15.2 0.7 1.3 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein ABC_tran_CTD PF16326.5 KIY47275.1 - 0.0099 16.1 2.9 0.92 9.8 0.2 2.3 2 0 0 2 2 2 2 ABC transporter C-terminal domain ZapB PF06005.12 KIY47275.1 - 0.017 15.6 0.8 0.017 15.6 0.8 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 KIY47275.1 - 0.023 14.1 1.1 0.027 13.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KIY47275.1 - 0.023 15.1 1.5 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KIY47275.1 - 0.036 14.4 4.4 1.2 9.4 0.7 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 KIY47275.1 - 0.086 12.8 1.9 3.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II NYD-SP28 PF14772.6 KIY47275.1 - 0.12 12.5 9.8 0.39 10.8 4.0 2.1 2 0 0 2 2 2 0 Sperm tail PCRF PF03462.18 KIY47275.1 - 0.14 12.0 4.7 0.23 11.3 4.7 1.4 1 1 0 1 1 1 0 PCRF domain Spc24 PF08286.11 KIY47275.1 - 0.17 12.1 6.2 0.56 10.5 0.4 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 THOC7 PF05615.13 KIY47275.1 - 0.28 11.5 5.6 0.87 9.9 5.5 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 DASH_Dad2 PF08654.10 KIY47275.1 - 0.3 11.5 3.0 4.8 7.7 0.8 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 bZIP_1 PF00170.21 KIY47275.1 - 1.8 8.8 5.5 14 5.9 0.6 2.3 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 KIY47275.1 - 3 7.7 8.5 6.3 6.7 1.0 2.4 1 1 1 2 2 2 0 Septum formation initiator Pyridoxal_deC PF00282.19 KIY47276.1 - 6.7e-20 71.1 0.0 1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIY47276.1 - 5.3e-11 42.1 0.0 5.5e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIY47276.1 - 2.8e-05 23.6 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIY47276.1 - 0.019 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Spt46 PF17734.1 KIY47278.1 - 3.3 7.4 5.8 42 3.8 0.1 3.5 1 1 2 3 3 3 0 Spermatogenesis-associated protein 46 ADH_zinc_N_2 PF13602.6 KIY47279.1 - 0.015 16.4 0.0 0.015 16.4 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ABC2_membrane PF01061.24 KIY47285.1 - 4.4e-73 245.2 50.5 1.3e-41 142.3 18.0 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KIY47285.1 - 7.5e-33 113.9 0.0 6.8e-15 55.8 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KIY47285.1 - 4.6e-32 109.8 17.5 8.6e-29 99.3 0.1 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY47285.1 - 3e-16 59.8 0.0 8.7e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIY47285.1 - 6.7e-07 29.8 0.4 0.0013 19.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY47285.1 - 2.3e-06 27.6 0.1 9.2e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIY47285.1 - 2.3e-05 24.7 0.5 0.05 13.9 0.1 2.8 2 1 0 2 2 2 2 AAA domain dNK PF01712.19 KIY47285.1 - 0.00044 20.2 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_25 PF13481.6 KIY47285.1 - 0.00081 19.0 0.3 0.027 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY47285.1 - 0.00083 19.3 0.3 0.23 11.3 0.1 2.5 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 KIY47285.1 - 0.0012 18.9 0.4 0.16 12.0 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC2_membrane_3 PF12698.7 KIY47285.1 - 0.0015 17.8 41.9 0.018 14.2 15.3 3.7 2 1 0 3 3 3 2 ABC-2 family transporter protein cobW PF02492.19 KIY47285.1 - 0.0018 17.9 1.1 0.13 11.9 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KIY47285.1 - 0.0018 18.1 0.0 0.43 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIY47285.1 - 0.0019 18.2 0.4 0.7 10.0 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KIY47285.1 - 0.002 17.8 0.7 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 KIY47285.1 - 0.0043 17.5 0.9 4.6 7.7 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIY47285.1 - 0.0044 16.7 0.3 0.23 11.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KIY47285.1 - 0.011 16.3 0.9 1 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KIY47285.1 - 0.012 15.3 0.3 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KIY47285.1 - 0.016 15.0 0.8 0.83 9.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KIY47285.1 - 0.019 14.4 0.0 0.41 10.0 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KIY47285.1 - 0.029 14.5 0.5 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KIY47285.1 - 0.052 14.0 0.6 8.4 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KIY47285.1 - 0.13 11.0 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KIY47285.1 - 0.14 11.5 0.5 5.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 KIY47285.1 - 0.16 12.5 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KIY47285.1 - 0.17 12.1 0.1 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KIY47285.1 - 0.2 11.6 0.1 15 5.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 KIY47285.1 - 0.22 11.7 4.3 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KIY47285.1 - 0.23 10.7 0.3 5.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Septin ABC2_membrane PF01061.24 KIY47286.1 - 0.00011 21.8 0.1 0.00011 21.8 0.1 1.4 2 0 0 2 2 2 1 ABC-2 type transporter HET PF06985.11 KIY47287.1 - 1.7e-16 60.9 0.3 3.1e-16 60.1 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NDUF_B8 PF05821.11 KIY47288.1 - 0.0037 17.1 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) CLZ PF16526.5 KIY47289.1 - 0.16 12.4 3.5 3.5 8.1 0.1 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TolA_bind_tri PF16331.5 KIY47289.1 - 0.84 9.8 7.1 3.3 7.9 4.3 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation PHC2_SAM_assoc PF16616.5 KIY47289.1 - 4.8 8.0 9.2 12 6.8 7.0 2.1 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Phosphorylase PF00343.20 KIY47291.1 - 6.6e-298 989.9 0.0 7.6e-298 989.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase NmrA PF05368.13 KIY47292.1 - 8.8e-33 113.8 0.0 1.2e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY47292.1 - 3.1e-12 46.8 0.0 4.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY47292.1 - 8e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY47292.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KIY47292.1 - 0.14 11.6 0.0 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KIY47292.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein gag-asp_proteas PF13975.6 KIY47295.1 - 7.2e-09 36.1 0.0 1.3e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY47295.1 - 4.1e-06 27.4 0.0 7.7e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 KIY47295.1 - 0.00072 19.3 0.0 0.00088 19.1 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Nop10p PF04135.12 KIY47296.1 - 0.025 14.6 1.8 0.057 13.5 1.8 1.6 1 1 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family RVT_1 PF00078.27 KIY47301.1 - 2.1e-06 27.4 0.0 5.7e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIY47302.1 - 8.8e-05 23.1 0.2 8.8e-05 23.1 0.2 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase AMP-binding PF00501.28 KIY47303.1 - 1.3e-78 264.5 0.0 1e-77 261.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY47303.1 - 8.4e-11 42.7 0.0 2.8e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 KIY47304.1 - 2.9e-16 59.5 15.7 0.0014 19.4 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIY47304.1 - 0.099 11.6 0.0 6.9 5.5 0.1 2.7 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arrestin_C PF02752.22 KIY47305.1 - 1e-10 42.2 0.0 2.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain ELFV_dehydrog PF00208.21 KIY47306.1 - 8.3e-78 261.5 0.4 1e-77 261.2 0.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KIY47306.1 - 1.6e-50 170.3 0.0 3.4e-50 169.3 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUSP PF06337.12 KIY47309.1 - 0.046 14.4 0.0 0.069 13.8 0.0 1.4 1 0 0 1 1 1 0 DUSP domain zf-MYND PF01753.18 KIY47310.1 - 0.0017 18.4 3.0 0.003 17.6 3.0 1.4 1 0 0 1 1 1 1 MYND finger Polysacc_synt_4 PF04669.13 KIY47312.1 - 2.2e-17 63.2 1.1 2.8e-15 56.4 1.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis Rhodanese PF00581.20 KIY47313.1 - 4.5e-11 43.2 0.0 5.9e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Trehalose_recp PF06151.13 KIY47314.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Trehalose receptor Med17 PF10156.9 KIY47314.1 - 0.39 9.4 0.5 0.5 9.0 0.5 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex FOG_N PF15888.5 KIY47315.1 - 0.086 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Folded gastrulation N-terminus Sec5 PF15469.6 KIY47316.1 - 7.5e-55 185.7 0.2 3.7e-54 183.4 0.1 2.3 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 KIY47316.1 - 0.031 14.3 0.0 0.1 12.7 0.0 2.0 1 0 0 1 1 1 0 Vps51/Vps67 DNA_primase_lrg PF04104.14 KIY47316.1 - 0.05 13.0 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit CK2S PF15011.6 KIY47316.1 - 0.079 12.8 1.1 0.47 10.3 0.1 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate Pre-PUA PF17832.1 KIY47317.1 - 1.6e-15 57.5 0.7 8.9e-15 55.2 0.1 2.5 3 0 0 3 3 3 1 Pre-PUA-like domain SUI1 PF01253.22 KIY47317.1 - 7.1e-15 55.3 1.5 1.5e-14 54.3 0.3 2.1 2 0 0 2 2 2 1 Translation initiation factor SUI1 PUA PF01472.20 KIY47317.1 - 7.2e-10 38.7 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 PUA domain Tma16 PF11176.8 KIY47317.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Translation machinery-associated protein 16 RepB-RCR_reg PF10723.9 KIY47317.1 - 0.061 13.3 0.1 0.63 10.0 0.0 2.5 2 0 0 2 2 2 0 Replication regulatory protein RepB Img2 PF05046.14 KIY47317.1 - 0.29 11.5 0.9 0.88 9.9 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) GTP-bdg_M PF16360.5 KIY47318.1 - 0.051 14.2 0.2 0.051 14.2 0.2 2.5 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region His_Phos_2 PF00328.22 KIY47319.1 - 8.2e-18 64.9 0.0 6.2e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DGF-1_C PF11040.8 KIY47319.1 - 0.14 12.2 0.3 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DCP1 PF06058.13 KIY47320.1 - 1.1e-18 67.3 0.0 2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 KIY47320.1 - 0.00061 19.0 0.0 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus P5CR_dimer PF14748.6 KIY47321.1 - 5.7e-40 135.7 0.8 1.2e-39 134.8 0.8 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KIY47321.1 - 7.2e-12 45.7 0.0 1.6e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 KIY47321.1 - 0.14 11.1 0.0 0.42 9.6 0.0 1.7 2 0 0 2 2 2 0 Prephenate dehydrogenase PIGA PF08288.12 KIY47322.1 - 2.1e-37 127.6 0.7 5.9e-37 126.1 0.7 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 KIY47322.1 - 1.4e-26 93.1 0.0 2.3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIY47322.1 - 1.5e-21 77.2 0.1 2.6e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIY47322.1 - 5e-19 68.9 5.8 6.4e-18 65.3 4.8 2.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIY47322.1 - 4.1e-07 30.6 0.1 9.9e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIY47322.1 - 0.00011 22.5 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIY47322.1 - 0.002 18.2 0.3 0.12 12.4 0.2 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like AAA_12 PF13087.6 KIY47323.1 - 5.1e-41 140.5 0.1 2.3e-39 135.1 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KIY47323.1 - 3e-25 89.5 0.0 4.1e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIY47323.1 - 3.8e-12 46.3 0.0 3e-11 43.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIY47323.1 - 1.8e-09 38.0 0.0 1.1e-08 35.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain zf-C2H2_jaz PF12171.8 KIY47323.1 - 1.3e-07 31.8 2.1 4.9e-06 26.7 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY47323.1 - 9.7e-06 25.8 5.4 0.00018 21.8 0.2 3.4 4 0 0 4 4 3 1 Zinc-finger of C2H2 type UvrD-helicase PF00580.21 KIY47323.1 - 8e-05 22.3 0.0 0.039 13.5 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KIY47323.1 - 0.0006 19.6 0.2 0.13 12.0 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KIY47323.1 - 0.0027 17.2 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein T2SSE PF00437.20 KIY47323.1 - 0.0032 16.6 0.0 0.0074 15.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KIY47323.1 - 0.0042 17.5 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIY47323.1 - 0.0078 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 KIY47323.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY47323.1 - 0.021 15.1 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIY47323.1 - 0.066 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_4 PF13894.6 KIY47323.1 - 0.1 13.5 0.7 1.4 9.9 0.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIY47323.1 - 0.11 12.9 0.8 0.59 10.5 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DEAD PF00270.29 KIY47323.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 KIY47323.1 - 0.15 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FhuF_C PF11575.8 KIY47323.1 - 0.17 11.8 0.6 0.37 10.7 0.6 1.6 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain DUF2075 PF09848.9 KIY47323.1 - 0.2 10.9 0.0 0.43 9.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) OrsD PF12013.8 KIY47323.1 - 0.31 11.5 3.1 13 6.3 0.2 2.6 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D AAA_12 PF13087.6 KIY47324.1 - 7.7e-39 133.4 0.1 1.3e-38 132.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY47324.1 - 9.3e-27 94.4 0.1 3.7e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIY47324.1 - 3.2e-13 49.8 0.0 2e-12 47.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIY47324.1 - 3.3e-10 40.5 0.0 1.6e-09 38.2 0.0 2.2 3 0 0 3 3 1 1 AAA domain zf-C2H2_jaz PF12171.8 KIY47324.1 - 2.3e-06 27.7 7.8 0.0021 18.3 0.2 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding UvrD-helicase PF00580.21 KIY47324.1 - 3.3e-05 23.6 0.0 0.0043 16.6 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KIY47324.1 - 7.2e-05 22.3 0.0 0.26 10.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.18 KIY47324.1 - 0.00027 20.7 0.5 0.038 13.7 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase zf-met PF12874.7 KIY47324.1 - 0.0003 21.1 7.6 0.012 15.9 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type AAA_16 PF13191.6 KIY47324.1 - 0.0023 18.3 0.0 0.0095 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KIY47324.1 - 0.009 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein zf-C2H2_2 PF12756.7 KIY47324.1 - 0.012 15.9 3.1 1.6 9.1 0.5 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_22 PF13401.6 KIY47324.1 - 0.02 15.2 0.0 0.051 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.6 KIY47324.1 - 0.02 15.7 0.6 16 6.6 0.1 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger ResIII PF04851.15 KIY47324.1 - 0.033 14.2 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-DBF PF07535.12 KIY47324.1 - 0.061 13.4 8.0 0.35 11.0 1.0 2.9 3 0 0 3 3 3 0 DBF zinc finger DEAD PF00270.29 KIY47324.1 - 0.063 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KIY47324.1 - 0.072 12.6 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KIY47324.1 - 0.13 12.7 0.0 0.48 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KIY47324.1 - 0.55 10.1 2.1 11 5.9 0.7 2.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ATP-synt_J PF04911.12 KIY47325.1 - 2.5e-20 71.8 3.3 4.2e-20 71.0 3.3 1.4 1 1 0 1 1 1 1 ATP synthase j chain AAA_12 PF13087.6 KIY47326.1 - 4.6e-37 127.6 0.0 7.5e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY47326.1 - 4.8e-21 75.7 0.0 5e-11 42.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIY47326.1 - 9.3e-11 41.8 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY47326.1 - 8e-08 32.7 0.0 2.6e-07 31.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain UvrD-helicase PF00580.21 KIY47326.1 - 1.4e-05 24.8 0.0 6e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KIY47326.1 - 0.0044 16.5 0.0 0.024 14.1 0.0 2.0 1 1 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.18 KIY47326.1 - 0.011 15.6 0.0 10 5.8 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KIY47326.1 - 0.017 15.5 0.1 0.07 13.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 KIY47326.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 KIY47326.1 - 0.035 14.5 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KIY47326.1 - 0.052 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIY47326.1 - 0.052 13.1 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIY47326.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIY47326.1 - 0.14 12.4 0.1 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KIY47327.1 - 9.2e-129 429.6 0.0 1.1e-128 429.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY47327.1 - 1.1e-05 24.9 0.1 0.00012 21.6 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA PF00004.29 KIY47329.1 - 4.1e-43 147.0 0.0 7.7e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY47329.1 - 6.3e-11 41.9 0.0 1.6e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIY47329.1 - 6.2e-08 32.9 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KIY47329.1 - 7.9e-08 32.1 0.3 1.8e-07 31.0 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KIY47329.1 - 2.6e-06 27.5 0.0 8.4e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY47329.1 - 7.1e-06 26.5 0.1 7.9e-05 23.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY47329.1 - 2.7e-05 24.5 1.7 0.0051 17.1 0.2 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KIY47329.1 - 6.3e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIY47329.1 - 0.00071 20.1 0.1 0.021 15.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 KIY47329.1 - 0.00096 18.5 0.0 0.0022 17.3 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KIY47329.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY47329.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KIY47329.1 - 0.0025 17.3 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 KIY47329.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KIY47329.1 - 0.0072 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KIY47329.1 - 0.0088 16.3 0.4 0.021 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KIY47329.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KIY47329.1 - 0.017 14.8 0.1 0.096 12.4 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 KIY47329.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 KIY47329.1 - 0.022 14.5 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2072 PF09845.9 KIY47329.1 - 0.022 15.0 0.2 0.046 14.0 0.2 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF815 PF05673.13 KIY47329.1 - 0.024 13.8 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KIY47329.1 - 0.029 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KIY47329.1 - 0.041 14.3 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KIY47329.1 - 0.041 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIY47329.1 - 0.051 12.8 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 KIY47329.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KIY47329.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIY47329.1 - 0.081 13.3 0.1 0.41 11.0 0.0 2.1 3 0 0 3 3 2 0 AAA domain DUF5406 PF17400.2 KIY47329.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5406) AAA_11 PF13086.6 KIY47329.1 - 0.15 11.8 0.2 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Insulin_TMD PF17870.1 KIY47330.1 - 0.013 15.6 1.3 0.029 14.4 1.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF2700 PF10912.8 KIY47330.1 - 0.15 12.1 1.9 0.32 11.0 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) Metallophos PF00149.28 KIY47331.1 - 1.8e-36 126.5 0.1 2.9e-36 125.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ssl1 PF04056.14 KIY47336.1 - 7.6e-73 244.4 0.0 9.8e-73 244.1 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KIY47336.1 - 1.2e-14 54.3 9.2 1.2e-14 54.3 9.2 3.3 4 0 0 4 4 4 1 TFIIH C1-like domain VWA_2 PF13519.6 KIY47336.1 - 1.4e-13 51.4 0.0 2.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KIY47336.1 - 0.063 12.8 5.9 1.8 7.9 6.0 2.3 2 1 0 2 2 2 0 Transcription factor Tfb4 VWA PF00092.28 KIY47336.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain DZR PF12773.7 KIY47336.1 - 5.3 7.2 24.3 6.7 6.8 4.4 3.3 2 1 0 2 2 2 0 Double zinc ribbon Phage_holin_1 PF04531.13 KIY47337.1 - 0.041 14.4 3.2 3.4 8.3 0.7 2.9 3 0 0 3 3 3 0 Bacteriophage holin PRELI PF04707.14 KIY47339.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 PRELI-like family p47_phox_C PF08944.11 KIY47339.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Aldo_ket_red PF00248.21 KIY47340.1 - 0.0006 19.1 0.0 0.00072 18.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.25 KIY47342.1 - 1.2e-06 28.7 0.0 2.5e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KIY47342.1 - 9.5e-05 22.5 0.0 0.0056 16.7 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY47342.1 - 0.0063 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY47342.1 - 0.0071 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.21 KIY47344.1 - 1.2e-05 24.6 0.0 1.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_tran PF00005.27 KIY47344.1 - 3.4e-05 24.4 0.0 7.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter CDC27 PF09507.10 KIY47347.1 - 0.022 14.2 10.0 0.029 13.8 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zn_clus PF00172.18 KIY47351.1 - 0.33 11.1 15.6 0.15 12.2 4.8 2.5 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UL11 PF11094.8 KIY47351.1 - 6 6.8 7.5 0.33 10.9 1.3 2.1 2 0 0 2 2 2 0 Membrane-associated tegument protein gag-asp_proteas PF13975.6 KIY47352.1 - 2.3e-05 24.8 0.0 5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY47352.1 - 0.0012 19.5 0.0 0.0027 18.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Ntox37 PF15535.6 KIY47356.1 - 0.009 16.4 6.9 0.021 15.2 6.9 1.6 1 0 0 1 1 1 1 Bacterial toxin 37 eIF3g PF12353.8 KIY47356.1 - 0.041 14.3 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G ArfGap PF01412.18 KIY47356.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf gag-asp_proteas PF13975.6 KIY47357.1 - 0.14 12.7 0.0 0.89 10.2 0.0 2.3 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF4730 PF15873.5 KIY47358.1 - 0.083 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4730) Nif11 PF07862.11 KIY47359.1 - 0.026 14.8 0.1 0.043 14.1 0.1 1.3 1 0 0 1 1 1 0 Nif11 domain Integrase_H2C2 PF17921.1 KIY47359.1 - 0.17 12.0 0.2 0.31 11.2 0.1 1.5 2 0 0 2 2 2 0 Integrase zinc binding domain RRM_1 PF00076.22 KIY47361.1 - 2e-14 53.2 0.0 3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KIY47361.1 - 7.3e-06 26.4 0.8 7.3e-06 26.4 0.8 2.6 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KIY47361.1 - 0.0053 16.6 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RNA_pol_3_Rpc31 PF11705.8 KIY47362.1 - 4e-26 92.7 8.4 5.5e-26 92.2 8.4 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Amidase PF01425.21 KIY47363.1 - 6.6e-124 414.3 0.4 8.1e-124 414.0 0.4 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.26 KIY47364.1 - 8.3e-30 103.4 0.9 1.7e-29 102.4 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY47364.1 - 2.7e-29 101.2 1.9 4.5e-29 100.5 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY47364.1 - 0.00018 22.6 0.2 0.00028 21.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KIY47364.1 - 0.043 13.3 0.3 0.27 10.6 0.4 2.3 3 1 0 3 3 3 0 short chain dehydrogenase TOBE_2 PF08402.10 KIY47364.1 - 0.13 12.4 1.1 0.53 10.5 0.0 2.5 3 0 0 3 3 3 0 TOBE domain SIT PF15330.6 KIY47365.1 - 0.12 12.9 1.1 0.21 12.1 0.3 1.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Ribosomal_L7Ae PF01248.26 KIY47366.1 - 4.5e-26 90.4 3.1 5.7e-26 90.1 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4911 PF16256.5 KIY47366.1 - 0.086 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) DEAD PF00270.29 KIY47368.1 - 1.2e-37 129.4 0.0 2.4e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY47368.1 - 9e-25 87.2 0.0 2.4e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY47368.1 - 0.00084 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY47368.1 - 0.0036 17.6 0.5 0.052 13.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain WD40 PF00400.32 KIY47369.1 - 4e-39 131.9 26.1 8.2e-08 32.8 0.0 11.9 14 0 0 14 14 14 7 WD domain, G-beta repeat Utp12 PF04003.12 KIY47369.1 - 3.9e-27 94.7 0.0 6.4e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KIY47369.1 - 3.8e-25 88.0 0.0 0.00022 21.5 0.0 8.8 3 2 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY47369.1 - 1.8e-11 43.6 2.5 0.034 13.1 0.0 6.8 4 3 4 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIY47369.1 - 1.8e-06 27.7 0.2 8.3 6.5 0.0 6.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIY47369.1 - 0.007 14.9 0.9 14 4.1 0.0 4.0 4 0 0 4 4 4 2 Cytochrome D1 heme domain WD40_like PF17005.5 KIY47369.1 - 0.024 14.0 0.0 6.6 6.0 0.0 3.2 2 1 1 3 3 3 0 WD40-like domain DEAD PF00270.29 KIY47370.1 - 2.5e-43 147.9 0.0 4.2e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY47370.1 - 8.3e-28 97.0 1.0 7.1e-27 94.0 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KIY47370.1 - 0.0049 16.3 0.0 0.0049 16.3 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Hydin_ADK PF17213.3 KIY47370.1 - 0.19 12.0 2.0 0.33 11.2 2.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain TFIIA PF03153.13 KIY47370.1 - 0.53 10.2 14.0 0.8 9.6 14.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KIY47370.1 - 3.1 7.3 19.9 5.4 6.6 19.9 1.3 1 0 0 1 1 1 0 Spt20 family DUF2076 PF09849.9 KIY47371.1 - 1.6e-05 25.1 4.7 2.2e-05 24.7 4.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KIY47371.1 - 0.14 12.3 1.3 0.35 11.0 1.3 1.7 1 1 0 1 1 1 0 CHCH domain Terpene_synth_C PF03936.16 KIY47372.1 - 4.9e-06 26.1 0.0 8.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain GvpD PF07088.11 KIY47372.1 - 0.022 13.4 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein SPOB_ab PF14682.6 KIY47372.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Gly_transf_sug PF04488.15 KIY47374.1 - 6.7e-08 33.1 0.0 1.3e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIY47374.1 - 0.00011 21.6 0.8 0.00022 20.7 0.8 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein MFS_1 PF07690.16 KIY47375.1 - 1e-18 67.4 36.0 5e-17 61.9 12.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Vps16_C PF04840.12 KIY47376.1 - 3.2e-88 295.9 0.2 4.1e-88 295.5 0.2 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 KIY47376.1 - 9.9e-84 281.5 0.0 1.3e-83 281.1 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region RIB43A PF05914.12 KIY47376.1 - 0.042 12.6 1.8 0.064 12.0 1.8 1.2 1 0 0 1 1 1 0 RIB43A MMR_HSR1 PF01926.23 KIY47377.1 - 4.4e-11 42.9 0.0 1.4e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY47377.1 - 8.5e-05 23.0 0.0 0.00022 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY47377.1 - 0.0079 16.1 0.1 0.025 14.5 0.0 1.9 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KIY47377.1 - 0.0097 15.5 0.3 0.018 14.5 0.3 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B MCM PF00493.23 KIY47377.1 - 0.016 14.3 0.2 0.056 12.5 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain IIGP PF05049.13 KIY47377.1 - 0.087 11.9 0.1 0.29 10.1 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Arf PF00025.21 KIY47377.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 KIY47377.1 - 0.13 11.6 0.8 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 KIY47377.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_18 PF13238.6 KIY47377.1 - 0.18 12.4 0.5 0.36 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIY47377.1 - 0.46 10.5 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Vps39_2 PF10367.9 KIY47377.1 - 1.8 9.0 4.3 26 5.3 3.3 2.6 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_3 PF13920.6 KIY47378.1 - 1.4e-13 50.4 6.6 1.4e-13 50.4 6.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY47378.1 - 3.2e-09 36.5 6.5 3.2e-09 36.5 6.5 2.6 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 KIY47378.1 - 7.1e-08 32.5 7.7 7.1e-08 32.5 7.7 2.7 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.6 KIY47378.1 - 4.5e-07 30.1 6.2 4.5e-07 30.1 6.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KIY47378.1 - 5.1e-05 23.1 7.7 5.1e-05 23.1 7.7 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY47378.1 - 0.00097 18.9 7.2 0.00097 18.9 7.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KIY47378.1 - 0.0017 18.0 3.1 0.0017 18.0 3.1 2.7 2 0 0 2 2 2 1 P-11 zinc finger FYVE_2 PF02318.16 KIY47378.1 - 0.0049 17.1 3.1 0.0049 17.1 3.1 3.6 3 1 1 4 4 4 1 FYVE-type zinc finger zf-RING_5 PF14634.6 KIY47378.1 - 0.018 15.0 4.9 0.018 15.0 4.9 2.7 2 0 0 2 2 2 0 zinc-RING finger domain SAP30_Sin3_bdg PF13867.6 KIY47378.1 - 0.076 13.4 0.1 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-RING_4 PF14570.6 KIY47378.1 - 2.1 8.2 18.8 0.45 10.3 4.9 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain O-FucT PF10250.9 KIY47379.1 - 3.4e-09 36.9 0.0 8.8e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TPT PF03151.16 KIY47380.1 - 3.2e-10 39.8 20.9 4e-10 39.5 20.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIY47380.1 - 0.0003 21.0 33.9 0.016 15.4 10.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF5381 PF17353.2 KIY47380.1 - 0.089 12.5 2.4 0.25 11.1 1.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5381) DUF4335 PF14233.6 KIY47381.1 - 0.052 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) RmlD_sub_bind PF04321.17 KIY47382.1 - 3.7e-51 173.9 0.0 4.7e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIY47382.1 - 5e-17 62.2 0.0 6.2e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY47382.1 - 1.3e-05 24.8 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIY47382.1 - 0.00035 19.8 0.0 0.0068 15.6 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIY47382.1 - 0.058 12.9 0.1 4.5 6.7 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Arrestin_C PF02752.22 KIY47383.1 - 0.0016 18.9 0.2 0.014 15.8 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain RSN1_7TM PF02714.15 KIY47384.1 - 1.3e-77 260.8 28.0 1.3e-77 260.8 28.0 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIY47384.1 - 1.9e-38 131.7 3.3 8.2e-38 129.6 3.3 2.2 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIY47384.1 - 8.8e-28 97.7 0.1 1.3e-20 74.3 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KIY47384.1 - 9e-13 48.2 0.3 3.2e-12 46.5 0.3 2.0 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter GRAB PF10375.9 KIY47386.1 - 6.4e-07 29.0 1.1 1.4e-06 27.9 1.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.20 KIY47386.1 - 0.013 15.4 0.0 0.048 13.6 0.0 2.0 1 0 0 1 1 1 0 GRIP domain BLOC1_2 PF10046.9 KIY47386.1 - 0.015 15.6 4.8 0.015 15.6 4.8 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PKHD_C PF18331.1 KIY47386.1 - 0.017 15.1 0.6 0.49 10.5 0.0 3.0 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain DUF2935 PF11155.8 KIY47386.1 - 0.066 13.6 5.2 0.6 10.5 2.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) FliD_N PF02465.18 KIY47386.1 - 0.36 11.5 12.0 3.5 8.4 1.9 3.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fez1 PF06818.15 KIY47386.1 - 1 9.8 47.9 4.9 7.6 31.1 3.1 1 1 1 2 2 2 0 Fez1 GldM_N PF12081.8 KIY47386.1 - 1.6 8.8 12.6 5.7 7.0 4.0 2.4 1 1 1 2 2 2 0 GldM N-terminal domain DUF1759 PF03564.15 KIY47386.1 - 1.6 8.6 10.1 0.089 12.7 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) Tn7_Tnp_TnsA_C PF08721.11 KIY47386.1 - 1.9 9.2 8.0 0.38 11.4 1.5 3.0 2 1 1 3 3 3 0 TnsA endonuclease C terminal LPP PF04728.13 KIY47386.1 - 4.6 7.7 10.8 0.15 12.4 2.2 2.9 2 2 0 2 2 2 0 Lipoprotein leucine-zipper FIN1 PF17300.2 KIY47388.1 - 0.027 14.0 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Herpes_TAF50 PF03326.13 KIY47389.1 - 0.0017 17.2 1.9 0.002 16.9 1.9 1.1 1 0 0 1 1 1 1 Herpesvirus transcription activation factor (transactivator) Pkinase PF00069.25 KIY47390.1 - 2.9e-64 217.0 0.0 5.1e-64 216.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47390.1 - 4.5e-32 111.4 0.0 8.1e-32 110.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY47390.1 - 0.0024 17.8 0.0 0.013 15.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY47390.1 - 0.067 12.5 0.0 7.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KIY47390.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain MitoNEET_N PF10660.9 KIY47391.1 - 0.042 13.9 0.0 0.29 11.2 0.0 2.5 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus 6PF2K PF01591.18 KIY47392.1 - 2.5e-62 210.1 0.0 3.9e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KIY47392.1 - 1.2e-23 83.8 0.0 4.7e-23 81.9 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KIY47392.1 - 0.00012 22.3 0.1 0.00055 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KIY47392.1 - 0.0039 16.7 0.0 0.0064 16.0 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Toprim_3 PF13362.6 KIY47392.1 - 0.098 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Toprim domain PB1 PF00564.24 KIY47393.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 PB1 domain Ribosomal_S5_C PF03719.15 KIY47394.1 - 9.4e-20 69.9 0.0 2.5e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KIY47394.1 - 8.8e-14 51.2 1.3 2.1e-13 50.0 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF4661 PF15576.6 KIY47395.1 - 1 9.2 5.5 0.9 9.4 2.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) Pkinase PF00069.25 KIY47396.1 - 6.2e-49 166.7 0.0 7.5e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47396.1 - 1.1e-26 93.7 0.0 1.2e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY47396.1 - 5.3e-05 22.7 0.0 0.00019 20.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 KIY47396.1 - 0.00022 20.3 0.9 0.00026 20.1 0.1 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.23 KIY47396.1 - 0.0016 18.4 0.7 0.0068 16.3 0.7 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY47396.1 - 0.02 14.3 0.3 0.029 13.7 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5127 PF17168.4 KIY47397.1 - 7.4e-75 251.6 3.9 1.3e-74 250.8 3.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIY47397.1 - 7.2e-64 214.6 2.9 1.8e-63 213.4 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIY47397.1 - 3.2e-59 200.1 3.5 8.1e-59 198.8 3.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIY47397.1 - 6.8e-08 32.0 0.1 2.3e-07 30.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) HalX PF08663.10 KIY47397.1 - 0.23 11.8 0.0 0.43 10.9 0.0 1.3 1 0 0 1 1 1 0 HalX domain Syntaxin-6_N PF09177.11 KIY47398.1 - 3.7e-27 94.8 5.5 5.2e-26 91.1 0.5 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KIY47398.1 - 1.1e-09 38.1 0.7 2.6e-09 36.9 0.7 1.7 1 0 0 1 1 1 1 SNARE domain XhlA PF10779.9 KIY47398.1 - 0.00032 20.8 1.5 0.22 11.7 0.6 3.1 2 1 1 3 3 3 2 Haemolysin XhlA Use1 PF09753.9 KIY47398.1 - 0.00039 20.2 1.2 0.00061 19.6 1.1 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 JAKMIP_CC3 PF16034.5 KIY47398.1 - 0.00054 20.0 0.3 0.0016 18.4 0.3 1.7 1 1 0 1 1 1 1 JAKMIP CC3 domain PspA_IM30 PF04012.12 KIY47398.1 - 0.0027 17.3 2.7 0.027 14.1 0.8 2.4 2 0 0 2 2 2 1 PspA/IM30 family FliJ PF02050.16 KIY47398.1 - 0.0028 17.8 4.2 0.54 10.5 3.2 2.8 2 1 0 2 2 2 1 Flagellar FliJ protein DUF1640 PF07798.11 KIY47398.1 - 0.0029 17.7 1.6 1.4 9.0 0.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1640) DUF3040 PF11239.8 KIY47398.1 - 0.0051 17.1 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Spc7 PF08317.11 KIY47398.1 - 0.0084 15.0 7.4 0.03 13.2 0.3 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein Prominin PF05478.11 KIY47398.1 - 0.01 13.9 1.2 0.012 13.6 0.2 1.6 2 0 0 2 2 2 1 Prominin FlaC_arch PF05377.11 KIY47398.1 - 0.016 15.6 1.8 5.6 7.4 0.0 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 KIY47398.1 - 0.033 14.0 0.8 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF5446 PF17522.2 KIY47398.1 - 0.059 13.5 5.1 0.22 11.7 0.1 3.1 2 1 0 3 3 3 0 Family of unknown function (DUF5446) Prefoldin_2 PF01920.20 KIY47398.1 - 0.082 12.9 2.3 9 6.3 0.5 2.6 2 0 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.6 KIY47398.1 - 0.097 13.1 0.6 0.097 13.1 0.6 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) RmuC PF02646.16 KIY47398.1 - 0.15 11.2 2.6 1.6 7.8 0.7 2.2 2 0 0 2 2 2 0 RmuC family Seryl_tRNA_N PF02403.22 KIY47398.1 - 0.32 11.2 2.9 6.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KIY47398.1 - 0.37 10.8 6.2 4 7.5 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 KIY47398.1 - 0.65 8.6 2.5 0.45 9.1 0.3 1.7 2 0 0 2 2 2 0 AAA domain Lebercilin PF15619.6 KIY47398.1 - 0.85 9.2 5.7 2.6 7.7 0.2 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease APG17 PF04108.12 KIY47398.1 - 1.2 8.2 8.5 0.81 8.7 1.4 2.4 2 1 0 2 2 2 0 Autophagy protein Apg17 DUF4200 PF13863.6 KIY47398.1 - 1.3 9.5 8.8 1.4 9.3 1.6 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) DUF724 PF05266.14 KIY47398.1 - 2.4 8.0 5.4 3.3 7.5 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF641 PF04859.12 KIY47398.1 - 2.9 8.3 6.5 6 7.2 0.1 2.6 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) zf-C4H2 PF10146.9 KIY47398.1 - 5.1 7.3 6.8 13 6.1 1.5 2.1 1 1 0 2 2 2 0 Zinc finger-containing protein TPR_MLP1_2 PF07926.12 KIY47398.1 - 7.8 6.6 10.3 6.9 6.7 0.3 3.0 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein SWIRM PF04433.17 KIY47399.1 - 2.3e-32 111.2 0.0 7.7e-32 109.5 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KIY47399.1 - 7.5e-21 73.9 11.4 1.4e-20 73.0 11.4 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KIY47399.1 - 2.1e-10 40.6 0.1 4.4e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY47399.1 - 1e-08 35.3 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KIY47399.1 - 1.1e-06 28.3 3.9 1.9e-06 27.6 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Chordopox_RPO7 PF05864.12 KIY47399.1 - 0.67 10.3 3.3 1.5 9.1 0.7 2.4 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) His_Phos_1 PF00300.22 KIY47400.1 - 1.2e-35 123.0 0.1 2.1e-35 122.2 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FMO-like PF00743.19 KIY47401.1 - 2.3e-39 135.2 0.0 1.8e-28 99.3 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY47401.1 - 7.5e-15 55.0 0.0 9.8e-14 51.3 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY47401.1 - 7.2e-10 39.1 0.1 6.2e-08 32.8 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIY47401.1 - 1.5e-09 37.5 0.0 6.7e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY47401.1 - 2.4e-07 30.2 0.0 9e-06 25.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIY47401.1 - 1.7e-05 24.5 0.0 0.13 11.8 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY47401.1 - 5.8e-05 23.2 0.0 0.00017 21.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIY47401.1 - 0.00047 19.6 0.2 0.26 10.5 0.0 2.9 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 KIY47401.1 - 0.0013 18.0 0.2 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KIY47401.1 - 0.31 9.7 0.3 0.68 8.6 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Chromo PF00385.24 KIY47402.1 - 2.5e-09 36.9 0.0 4.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KIY47402.1 - 2.1e-07 30.7 2.8 2.1e-07 30.7 2.8 2.0 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 KIY47402.1 - 0.027 14.3 1.3 0.058 13.3 0.2 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FMO-like PF00743.19 KIY47403.1 - 3.6e-30 104.9 0.0 2.6e-19 69.1 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY47403.1 - 7.9e-15 54.9 0.0 2.6e-13 49.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY47403.1 - 4e-06 26.3 0.0 3.5e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY47403.1 - 0.00042 19.6 0.0 0.0018 17.5 0.0 1.8 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KIY47403.1 - 0.078 12.2 0.1 0.73 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KIY47403.1 - 0.15 12.6 0.0 0.48 11.0 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY47403.1 - 0.2 10.3 0.0 3.5 6.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Sec20 PF03908.13 KIY47404.1 - 1.3e-15 57.1 1.8 2.5e-15 56.2 0.2 2.1 2 1 0 2 2 2 1 Sec20 Use1 PF09753.9 KIY47404.1 - 0.016 15.0 1.2 0.023 14.4 1.2 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Apq12 PF12716.7 KIY47404.1 - 0.37 10.8 2.8 0.74 9.8 2.8 1.5 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis F-box PF00646.33 KIY47405.1 - 0.0076 16.1 0.1 0.028 14.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY47405.1 - 0.53 10.2 2.7 0.73 9.8 0.0 2.6 3 0 0 3 3 3 0 F-box-like Ribophorin_II PF05817.14 KIY47406.1 - 5.2e-26 91.4 0.0 6.4e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyco_hydro_47 PF01532.20 KIY47407.1 - 4.7e-128 428.0 4.5 5.3e-128 427.8 4.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 p450 PF00067.22 KIY47408.1 - 3.1e-32 111.9 0.0 4.9e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.11 KIY47408.1 - 0.023 14.9 0.0 3.4 7.9 0.0 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Neugrin PF06413.11 KIY47409.1 - 3.3e-10 40.4 0.4 4.7e-10 39.9 0.4 1.2 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 KIY47409.1 - 3.8e-05 23.9 1.3 4.9e-05 23.6 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Acetyltransf_1 PF00583.25 KIY47410.1 - 3.9e-16 59.3 0.0 5.1e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY47410.1 - 3.2e-07 30.7 0.0 5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY47410.1 - 4.9e-06 26.5 0.0 6.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY47410.1 - 0.0095 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KIY47410.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KIY47410.1 - 0.14 12.9 0.0 0.17 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAC PF01849.18 KIY47411.1 - 2.8e-24 84.8 0.1 4.9e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 NAC domain Cofilin_ADF PF00241.20 KIY47412.1 - 6.2e-22 77.7 0.0 7e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HlyIII PF03006.20 KIY47413.1 - 5.1e-61 206.2 22.8 5.1e-61 206.2 22.8 1.5 2 0 0 2 2 2 1 Haemolysin-III related Tmemb_18A PF09771.9 KIY47413.1 - 0.24 11.8 1.4 0.56 10.6 0.1 2.2 2 1 0 2 2 2 0 Transmembrane protein 188 PMP22_Claudin PF00822.20 KIY47413.1 - 4.8 7.0 13.0 0.032 14.1 2.0 2.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF4604 PF15377.6 KIY47414.1 - 3.7e-23 82.8 5.2 8.8e-23 81.6 5.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Coatomer_WDAD PF04053.14 KIY47415.1 - 4.3e-136 454.5 0.0 8e-136 453.6 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KIY47415.1 - 2.6e-109 365.7 0.0 3.6e-109 365.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KIY47415.1 - 2.5e-43 145.2 12.7 4.5e-07 30.5 0.3 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY47415.1 - 1e-10 41.8 0.1 0.022 15.0 0.0 6.2 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY47415.1 - 0.027 13.1 2.7 1 7.9 0.2 3.2 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 KIY47415.1 - 0.099 12.5 0.7 1.3 8.8 0.2 2.7 2 1 1 3 3 3 0 Region in Clathrin and VPS PspA_IM30 PF04012.12 KIY47415.1 - 0.19 11.3 1.3 0.37 10.3 1.3 1.4 1 0 0 1 1 1 0 PspA/IM30 family TPR_14 PF13428.6 KIY47415.1 - 3 8.9 6.3 1e+02 4.1 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY47415.1 - 7.3 7.0 6.7 16 5.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat XPG_I PF00867.18 KIY47416.1 - 2.1e-15 56.8 0.0 4.3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIY47416.1 - 0.0001 22.7 0.0 0.0002 21.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc_N PF02739.16 KIY47416.1 - 0.003 17.5 0.2 2.1 8.2 0.1 2.3 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KIY47416.1 - 0.015 15.9 0.0 0.084 13.5 0.0 2.1 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold His_Phos_1 PF00300.22 KIY47419.1 - 2.3e-10 40.5 0.1 1.3e-09 38.1 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CLTH PF10607.9 KIY47421.1 - 1.1e-32 112.9 0.1 2.6e-32 111.7 0.1 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain PX PF00787.24 KIY47422.1 - 1.5e-19 70.1 0.0 2.6e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 KIY47422.1 - 2.5e-14 53.3 0.6 6.1e-14 52.1 0.5 1.6 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 KIY47422.1 - 1.2e-07 31.2 0.0 2.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY47422.1 - 1e-05 25.3 0.3 2.1e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain DarT PF14487.6 KIY47424.1 - 0.066 13.0 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 ssDNA thymidine ADP-ribosyltransferase, DarT Aldo_ket_red PF00248.21 KIY47425.1 - 5.2e-43 147.3 0.0 2.6e-41 141.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Tautomerase_2 PF14552.6 KIY47425.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Tautomerase enzyme DUF3124 PF11322.8 KIY47425.1 - 0.055 13.7 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) PIG-S PF10510.9 KIY47426.1 - 1.1e-104 351.2 3.0 3.7e-94 316.4 0.4 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein WW PF00397.26 KIY47429.1 - 0.027 14.5 0.1 0.08 13.1 0.1 1.9 1 0 0 1 1 1 0 WW domain PCI PF01399.27 KIY47430.1 - 3.9e-21 75.5 0.0 1.3e-20 73.9 0.0 1.9 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 KIY47430.1 - 6.6e-21 74.5 1.3 2e-20 72.9 1.3 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal Sigma70_r1_2 PF00140.20 KIY47430.1 - 0.54 10.3 3.0 2.4 8.2 3.0 2.1 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 NDUFA12 PF05071.16 KIY47431.1 - 2e-08 34.9 0.4 3.7e-08 34.1 0.4 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Myb_DNA-bind_6 PF13921.6 KIY47432.1 - 4.5e-05 23.6 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIY47432.1 - 8.3e-05 22.7 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rotamase_3 PF13616.6 KIY47433.1 - 1.3e-20 74.1 0.1 2.1e-20 73.4 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KIY47433.1 - 2.8e-16 60.2 0.0 3.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KIY47433.1 - 6.8e-05 23.7 0.0 8.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain PITH PF06201.13 KIY47435.1 - 1.3e-25 90.4 0.0 1.6e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain CBS PF00571.28 KIY47436.1 - 1.8e-14 53.9 0.3 0.029 14.8 0.0 5.4 5 0 0 5 5 5 5 CBS domain Methyltransf_2 PF00891.18 KIY47437.1 - 5.9e-12 45.3 0.0 8.8e-11 41.5 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KIY47437.1 - 0.036 13.6 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Bac_small_YrzI PF09501.10 KIY47438.1 - 0.084 13.0 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Retrotran_gag_2 PF14223.6 KIY47440.1 - 1.8e-09 37.3 0.1 2.2e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type KDZ PF18758.1 KIY47443.1 - 1.1e-19 70.9 0.5 1.6e-19 70.4 0.2 1.4 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIY47446.1 - 9.3e-90 300.1 0.3 1.1e-89 299.9 0.3 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Pkinase PF00069.25 KIY47449.1 - 2.3e-07 30.4 0.0 2.7e-05 23.7 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47449.1 - 0.016 14.5 0.1 0.15 11.3 0.0 2.2 2 1 0 2 2 2 0 Protein tyrosine kinase DUF3371 PF11851.8 KIY47449.1 - 0.12 13.4 0.0 0.23 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) TMP-TENI PF02581.17 KIY47450.1 - 2.6e-26 92.1 0.7 7.1e-23 80.9 0.1 2.0 1 1 1 2 2 2 2 Thiamine monophosphate synthase Clr5 PF14420.6 KIY47453.1 - 0.0068 16.6 0.1 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 Clr5 domain gag-asp_proteas PF13975.6 KIY47454.1 - 2.4e-05 24.8 0.0 5.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 KIY47454.1 - 0.0082 16.2 6.8 0.017 15.1 6.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIY47454.1 - 0.015 15.1 3.7 0.034 14.0 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 KIY47454.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 KIY47454.1 - 0.1 13.2 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease FTR1 PF03239.14 KIY47457.1 - 1.3e-59 201.9 7.9 1.6e-59 201.6 7.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF2456 PF10445.9 KIY47457.1 - 6.1 7.0 7.3 1.9 8.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) Cu-oxidase_2 PF07731.14 KIY47458.1 - 5.7e-36 123.3 2.1 9.5e-35 119.3 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KIY47458.1 - 7.2e-31 107.5 0.5 3.7e-26 92.1 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY47458.1 - 9.5e-29 99.8 4.0 3.9e-28 97.9 0.1 3.1 4 0 0 4 4 4 1 Multicopper oxidase RRM_1 PF00076.22 KIY47459.1 - 3.8e-32 109.9 0.0 2.5e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3932 PF13068.6 KIY47459.1 - 0.0075 16.5 0.0 5.5 7.3 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3932) RRM_7 PF16367.5 KIY47459.1 - 0.026 14.6 0.0 6.4 7.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif MFS_1 PF07690.16 KIY47460.1 - 2.6e-30 105.6 36.3 2.6e-30 105.6 36.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_transf_90 PF05686.12 KIY47462.1 - 1.4e-13 50.6 2.2 5.7e-07 28.8 0.0 3.4 4 0 0 4 4 4 3 Glycosyl transferase family 90 Aldo_ket_red PF00248.21 KIY47463.1 - 6.2e-60 202.9 0.0 7.9e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_tran PF00005.27 KIY47464.1 - 1.2e-48 165.1 0.0 1.2e-24 87.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KIY47464.1 - 6.8e-41 140.0 37.3 7.2e-25 87.6 16.9 2.8 2 1 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 KIY47464.1 - 1.9e-14 54.2 1.3 0.0028 17.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY47464.1 - 1.9e-08 34.9 0.2 0.004 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY47464.1 - 5.4e-08 32.9 0.1 0.01 15.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KIY47464.1 - 6.6e-07 29.0 0.3 0.0078 15.7 0.1 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY47464.1 - 7.7e-07 29.8 0.1 0.055 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY47464.1 - 1e-06 28.3 2.0 0.013 15.2 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY47464.1 - 1.4e-06 28.6 0.3 0.026 14.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 KIY47464.1 - 2.4e-05 24.3 0.1 0.28 11.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 KIY47464.1 - 3.4e-05 24.1 1.5 0.034 14.4 0.9 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KIY47464.1 - 9.2e-05 22.3 0.0 3.6 7.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KIY47464.1 - 0.0001 22.9 0.1 0.75 10.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KIY47464.1 - 0.00026 21.4 0.1 0.63 10.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 KIY47464.1 - 0.00036 20.3 0.2 1.1 8.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 KIY47464.1 - 0.00041 19.7 0.0 0.19 11.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 KIY47464.1 - 0.00046 19.8 0.3 0.32 10.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain PDR_assoc PF08370.11 KIY47464.1 - 0.0011 18.6 1.7 0.0039 16.9 1.7 1.9 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA PF00004.29 KIY47464.1 - 0.0014 19.0 0.0 4.2 7.8 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIY47464.1 - 0.0018 18.4 0.2 4.4 7.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain NTPase_1 PF03266.15 KIY47464.1 - 0.0025 17.7 0.1 2.6 7.9 0.0 3.5 4 0 0 4 4 4 1 NTPase AAA_5 PF07728.14 KIY47464.1 - 0.0032 17.5 0.2 2.2 8.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KIY47464.1 - 0.0037 17.0 0.1 3.9 7.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIY47464.1 - 0.0058 16.6 0.1 0.098 12.6 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea cobW PF02492.19 KIY47464.1 - 0.01 15.4 1.7 2.1 7.9 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KIY47464.1 - 0.011 16.1 0.0 1.6 9.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 KIY47464.1 - 0.011 15.4 0.5 0.44 10.2 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 KIY47464.1 - 0.011 16.1 0.4 0.89 10.0 0.3 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIY47464.1 - 0.016 15.0 0.0 3.6 7.3 0.1 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KIY47464.1 - 0.016 15.3 1.6 4 7.6 0.7 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 KIY47464.1 - 0.021 14.6 0.0 6 6.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family T2SSE PF00437.20 KIY47464.1 - 0.027 13.5 0.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein dNK PF01712.19 KIY47464.1 - 0.034 14.0 0.0 3.8 7.3 0.0 2.7 3 0 0 3 3 3 0 Deoxynucleoside kinase Rad17 PF03215.15 KIY47464.1 - 0.063 13.2 0.0 14 5.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 KIY47464.1 - 0.13 12.4 3.5 13 5.8 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain MobB PF03205.14 KIY47464.1 - 0.17 11.7 0.3 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.12 KIY47464.1 - 0.23 10.9 2.2 0.49 9.8 0.3 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_13 PF13166.6 KIY47464.1 - 0.33 9.6 0.3 1.6 7.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KIY47465.1 - 0.036 14.5 0.0 0.15 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain MR_MLE_C PF13378.6 KIY47466.1 - 1.6e-55 188.1 0.2 2.2e-55 187.6 0.2 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIY47466.1 - 7e-23 81.1 0.0 2.1e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Histone PF00125.24 KIY47467.1 - 2.3e-22 79.8 2.6 2.8e-22 79.5 2.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIY47467.1 - 2.5e-05 24.4 0.1 6.7e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIY47467.1 - 0.00035 21.0 0.0 0.00063 20.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KIY47467.1 - 0.032 14.3 0.3 0.039 14.0 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KIY47467.1 - 0.076 12.7 0.2 0.2 11.3 0.1 1.7 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KIY47468.1 - 6.2e-18 64.2 2.3 1.2e-17 63.3 2.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KIY47468.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIY47468.1 - 1.5e-06 28.4 0.0 2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BTB PF00651.31 KIY47469.1 - 0.001 19.3 0.1 0.0038 17.4 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain YidD PF01809.18 KIY47469.1 - 0.012 15.5 0.4 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor Prok-E2_B PF14461.6 KIY47469.1 - 0.19 11.4 1.5 0.21 11.3 0.1 1.9 3 0 0 3 3 3 0 Prokaryotic E2 family B 2-Hacid_dh_C PF02826.19 KIY47470.1 - 3e-20 72.3 0.0 4.1e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain JAB PF01398.21 KIY47471.1 - 1.1e-16 60.9 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KIY47471.1 - 2.2e-06 27.4 0.1 4.2e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-MYND PF01753.18 KIY47472.1 - 2.8e-06 27.3 8.6 2.8e-06 27.3 8.6 2.1 3 0 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 KIY47472.1 - 0.016 15.5 7.6 0.032 14.5 7.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Peroxin-3 PF04882.12 KIY47473.1 - 1.2e-113 380.6 0.1 1.4e-113 380.4 0.1 1.0 1 0 0 1 1 1 1 Peroxin-3 PRP38 PF03371.15 KIY47474.1 - 9.7e-59 198.1 0.3 1.1e-58 197.9 0.3 1.0 1 0 0 1 1 1 1 PRP38 family HEAT_2 PF13646.6 KIY47474.1 - 0.033 14.6 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats PWI PF01480.17 KIY47475.1 - 9.6e-29 99.5 0.0 1.4e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 PWI domain EMP24_GP25L PF01105.24 KIY47476.1 - 3.6e-40 137.9 0.0 4e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 KIY47476.1 - 0.013 15.0 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Trimerisation motif TRPM_tetra PF16519.5 KIY47476.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM TolA_bind_tri PF16331.5 KIY47476.1 - 0.19 11.8 0.6 0.34 11.0 0.6 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Brix PF04427.18 KIY47477.1 - 1.9e-31 109.7 0.4 2.7e-31 109.2 0.4 1.2 1 0 0 1 1 1 1 Brix domain DIOX_N PF14226.6 KIY47478.1 - 1.6e-26 93.4 0.0 2.4e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY47478.1 - 2.3e-17 63.3 0.0 4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Homoserine_dh PF00742.19 KIY47479.1 - 1.6e-49 168.2 0.0 2.4e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KIY47479.1 - 4.2e-18 66.1 0.0 7.2e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ubiquitin PF00240.23 KIY47480.1 - 1.4e-11 43.9 0.0 2.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 KIY47480.1 - 2.2e-06 28.0 1.0 5.1e-06 26.9 1.0 1.6 1 0 0 1 1 1 1 Blt1 N-terminal domain Rad60-SLD PF11976.8 KIY47480.1 - 0.0032 17.2 0.0 0.0066 16.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HipN PF18253.1 KIY47480.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain CHCH PF06747.13 KIY47481.1 - 0.022 14.9 3.2 1.3 9.3 1.0 2.3 1 1 1 2 2 2 0 CHCH domain COX6B PF02297.17 KIY47481.1 - 1 9.7 6.4 11 6.3 4.3 2.2 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Syja_N PF02383.18 KIY47483.1 - 1e-69 235.3 0.0 1.5e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KIY47483.1 - 3.1e-10 40.0 0.1 6.6e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sec2p PF06428.11 KIY47484.1 - 5.1e-16 58.4 12.1 1.3e-15 57.1 8.9 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Filament PF00038.21 KIY47484.1 - 0.00022 20.9 2.6 0.00022 20.9 2.6 2.1 1 1 1 2 2 2 1 Intermediate filament protein YabA PF06156.13 KIY47484.1 - 0.0013 19.3 5.4 0.011 16.3 0.3 2.3 2 0 0 2 2 2 1 Initiation control protein YabA COG5 PF10392.9 KIY47484.1 - 0.02 15.1 3.5 1.9 8.7 0.1 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.19 KIY47484.1 - 0.24 9.3 2.0 0.32 8.9 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CC2-LZ PF16516.5 KIY47484.1 - 0.31 11.4 10.9 0.29 11.5 3.1 3.0 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FlxA PF14282.6 KIY47484.1 - 0.9 9.6 9.5 9.9 6.2 0.1 2.6 2 1 0 2 2 2 0 FlxA-like protein TMF_TATA_bd PF12325.8 KIY47484.1 - 0.92 9.8 12.6 2.8 8.2 3.4 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 KIY47484.1 - 0.98 8.7 11.4 3.4 7.0 11.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KIY47484.1 - 2.4 8.6 9.7 3.5 8.0 9.7 1.2 1 0 0 1 1 1 0 Fez1 DUF1682 PF07946.14 KIY47484.1 - 6 6.0 8.9 0.049 12.8 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Mitoc_mL59 PF18126.1 KIY47485.1 - 6.8e-38 129.9 0.2 1e-37 129.3 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Methyltransf_33 PF10017.9 KIY47486.1 - 5.2e-76 255.7 0.0 8e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KIY47486.1 - 5.1e-19 68.9 4.0 1.7e-09 37.7 1.2 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KIY47486.1 - 1.3e-06 29.0 2.4 2.5e-06 28.0 2.4 1.5 1 0 0 1 1 1 1 DinB superfamily RRM_1 PF00076.22 KIY47487.1 - 1.3e-11 44.2 0.0 2.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KIY47487.1 - 3.9e-06 27.3 0.1 6.5e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF1191 PF06697.12 KIY47487.1 - 0.097 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) UQ_con PF00179.26 KIY47488.1 - 1.8e-53 180.0 0.0 2e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY47488.1 - 0.0054 17.0 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KIY47488.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KIY47488.1 - 0.036 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain HMG_box PF00505.19 KIY47490.1 - 1.7e-10 41.2 0.5 1.7e-10 41.2 0.5 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 KIY47490.1 - 0.0054 16.1 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 KIY47490.1 - 0.065 13.8 0.2 0.13 12.9 0.2 1.5 1 0 0 1 1 1 0 HMG-box domain F-box-like PF12937.7 KIY47492.1 - 0.053 13.4 0.9 4.3 7.3 0.2 2.8 2 0 0 2 2 2 0 F-box-like NDUF_B7 PF05676.13 KIY47493.1 - 3.4e-28 97.2 5.2 4e-28 96.9 5.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ATG11 PF10377.9 KIY47494.1 - 1.1e-29 103.1 1.3 2.1e-29 102.2 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein 11 Sugar_tr PF00083.24 KIY47495.1 - 4.7e-77 259.8 21.9 5.3e-77 259.6 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY47495.1 - 4.3e-16 58.8 25.9 8.4e-16 57.8 23.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ASCH PF04266.14 KIY47496.1 - 0.038 14.6 0.0 0.098 13.2 0.0 1.7 2 0 0 2 2 2 0 ASCH domain DFP PF04127.15 KIY47499.1 - 2.5e-20 73.1 0.0 4.7e-12 46.1 0.0 2.1 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein F-box-like PF12937.7 KIY47500.1 - 0.0037 17.1 0.0 0.015 15.1 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY47500.1 - 0.0065 16.3 0.0 0.0065 16.3 0.0 3.3 4 0 0 4 4 4 1 F-box domain Fasciclin PF02469.22 KIY47501.1 - 1.2e-20 74.0 0.8 1.6e-12 47.7 0.0 2.8 2 1 0 2 2 2 2 Fasciclin domain DUF4458 PF14660.6 KIY47501.1 - 0.0048 17.1 1.2 0.098 12.9 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4458) Spike_rec_bind PF09408.10 KIY47501.1 - 0.02 14.6 0.4 0.02 14.6 0.4 1.7 2 0 0 2 2 2 0 Spike receptor binding domain GST_N_2 PF13409.6 KIY47502.1 - 1.1e-21 76.9 0.0 2.3e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY47502.1 - 9.1e-15 54.4 0.1 2.9e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY47502.1 - 1.1e-08 35.2 0.1 1.9e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY47502.1 - 9.5e-05 22.7 0.0 0.0019 18.5 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY47502.1 - 0.00047 20.3 0.1 0.00083 19.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 KIY47502.1 - 0.14 12.8 0.2 2.6 8.7 0.0 2.3 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 RRM_1 PF00076.22 KIY47503.1 - 1.4e-34 117.7 0.0 4e-19 68.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KIY47503.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KIY47503.1 - 0.21 11.6 0.2 1.1 9.3 0.0 2.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif TPR_8 PF13181.6 KIY47504.1 - 5.7e-10 38.6 2.6 0.48 10.8 0.1 6.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY47504.1 - 8.3e-08 31.8 15.6 0.00037 20.4 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY47504.1 - 1.4e-07 31.0 2.8 2.1 8.3 0.1 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY47504.1 - 1.3e-06 28.4 0.9 0.085 13.3 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY47504.1 - 1.7e-06 28.4 0.2 0.18 12.4 0.0 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY47504.1 - 1.2e-05 24.9 0.0 1.5 8.6 0.0 3.9 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 KIY47504.1 - 0.00018 21.7 3.6 0.48 10.7 0.1 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIY47504.1 - 0.0012 18.1 1.7 0.71 9.0 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY47504.1 - 0.0014 19.2 4.6 57 4.7 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY47504.1 - 0.016 16.0 6.8 4.4 8.4 0.1 6.4 5 2 2 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIY47504.1 - 0.041 14.0 1.0 1.9 8.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY47504.1 - 0.2 12.3 8.6 2.6 8.8 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY47504.1 - 2.1 8.6 6.9 41 4.5 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY47506.1 - 7e-08 32.1 3.1 0.35 11.2 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY47506.1 - 1.3e-07 31.2 13.9 0.00026 20.8 0.0 6.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY47506.1 - 4.6e-07 29.8 0.1 0.062 13.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY47506.1 - 6.8e-07 29.7 0.2 0.12 12.9 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY47506.1 - 2.7e-06 27.0 5.7 1.7 8.6 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY47506.1 - 4.5e-06 26.3 0.0 1 9.1 0.0 3.9 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 KIY47506.1 - 0.00012 22.3 0.3 0.65 10.3 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIY47506.1 - 0.00033 20.0 1.0 0.5 9.5 0.0 3.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY47506.1 - 0.00097 19.6 1.6 41 5.1 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY47506.1 - 0.0014 19.3 4.4 3.1 8.8 0.1 6.1 5 2 2 7 7 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY47506.1 - 0.0094 16.6 6.1 1.9 9.2 0.0 5.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY47506.1 - 0.015 15.4 0.3 1.3 9.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY47506.1 - 0.027 14.5 1.3 30 4.9 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat F-box-like PF12937.7 KIY47507.1 - 0.00025 20.9 5.4 0.00055 19.8 5.4 1.7 1 1 0 1 1 1 1 F-box-like PI3K_P85_iSH2 PF16454.5 KIY47507.1 - 0.0046 16.6 0.6 0.0057 16.3 0.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Syntaxin_2 PF14523.6 KIY47507.1 - 0.089 13.2 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 Syntaxin-like protein PgaD PF13994.6 KIY47508.1 - 0.04 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein TMEM51 PF15345.6 KIY47508.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 DUF4431 PF14485.6 KIY47509.1 - 0.35 10.7 7.9 40 4.1 0.1 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4431) WD40 PF00400.32 KIY47510.1 - 8.4e-21 73.9 28.3 1.4e-05 25.7 0.6 10.7 10 1 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY47510.1 - 2.9e-12 46.7 4.7 0.031 14.6 0.0 6.7 5 3 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIY47510.1 - 0.0021 17.9 0.1 0.69 9.9 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat CPSF_A PF03178.15 KIY47510.1 - 0.01 15.1 0.2 0.67 9.2 0.0 2.9 3 0 0 3 3 3 0 CPSF A subunit region Ge1_WD40 PF16529.5 KIY47510.1 - 0.016 14.1 1.7 1.4 7.8 0.0 4.1 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5114 PF17141.4 KIY47510.1 - 0.11 13.1 0.2 4.6 7.8 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF5114) RCC1_2 PF13540.6 KIY47510.1 - 0.67 9.8 3.1 16 5.4 0.5 3.5 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat 2-oxoacid_dh PF00198.23 KIY47512.1 - 4.1e-09 36.2 0.0 4.6e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) RVT_3 PF13456.6 KIY47513.1 - 0.053 13.3 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like 2-oxoacid_dh PF00198.23 KIY47515.1 - 4.6e-82 275.0 0.2 5.9e-82 274.6 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIY47515.1 - 1.7e-17 63.0 1.4 3.5e-17 62.0 1.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KIY47515.1 - 0.00035 21.2 0.2 0.27 11.9 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 KIY47515.1 - 0.00068 19.5 0.4 0.0015 18.4 0.4 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 KIY47515.1 - 0.018 14.9 0.1 0.05 13.4 0.1 1.7 1 1 1 2 2 2 0 Biotin-lipoyl like CDC27 PF09507.10 KIY47515.1 - 0.31 10.4 8.4 0.45 9.8 8.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PRCC PF10253.9 KIY47515.1 - 0.63 10.8 7.5 1.1 10.0 7.5 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Metallophos PF00149.28 KIY47516.1 - 3.2e-40 138.8 0.1 4.2e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY47516.1 - 4.8e-22 78.1 0.2 1.1e-21 77.0 0.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PH PF00169.29 KIY47517.1 - 9e-06 26.2 0.0 1e-05 26.0 0.0 1.0 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KIY47517.1 - 5.7e-05 23.5 0.0 6.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain DSPc PF00782.20 KIY47518.1 - 1.5e-24 86.3 0.0 2.4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY47518.1 - 0.0075 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIY47518.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain IF3_C PF00707.22 KIY47519.1 - 0.002 18.0 0.0 0.0045 16.9 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KIY47519.1 - 0.0039 16.9 1.6 0.011 15.4 0.2 2.0 1 1 1 2 2 2 1 Mitochondrial translation initiation factor Isochorismatase PF00857.20 KIY47520.1 - 1.2e-28 100.4 0.1 2.7e-28 99.3 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family PEP_mutase PF13714.6 KIY47520.1 - 0.021 14.3 0.2 0.032 13.7 0.2 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase AnmK PF03702.14 KIY47521.1 - 0.0083 15.3 0.0 0.013 14.7 0.0 1.2 1 1 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Sec62 PF03839.16 KIY47522.1 - 1e-52 178.8 1.3 2.1e-52 177.8 1.3 1.5 1 1 0 1 1 1 1 Translocation protein Sec62 DUF3413 PF11893.8 KIY47522.1 - 0.6 9.2 6.5 0.89 8.7 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) HECT_2 PF09814.9 KIY47523.1 - 8.4e-47 159.8 0.0 1.2e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF630 PF04783.12 KIY47523.1 - 0.98 9.6 4.4 7.4 6.8 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF630) Glyco_hydro_3_C PF01915.22 KIY47524.1 - 8.9e-53 179.3 0.1 1.6e-52 178.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY47524.1 - 1.7e-33 116.4 0.0 9.5e-33 113.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY47524.1 - 7.7e-21 74.0 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Git3 PF11710.8 KIY47526.1 - 6.2e-06 26.1 4.8 6.2e-06 26.1 4.8 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 SfLAP PF11139.8 KIY47526.1 - 0.0057 16.1 0.8 0.17 11.3 0.1 2.3 2 0 0 2 2 2 2 Sap, sulfolipid-1-addressing protein Dicty_CAR PF05462.11 KIY47526.1 - 0.021 14.0 9.3 0.054 12.6 9.3 1.7 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor EXS PF03124.14 KIY47527.1 - 1.4e-70 238.3 25.9 1.3e-69 235.1 25.9 2.0 1 1 0 1 1 1 1 EXS family SPX PF03105.19 KIY47527.1 - 5.9e-21 75.8 0.2 8.2e-21 75.3 0.2 1.1 1 0 0 1 1 1 1 SPX domain Glyco_transf_8C PF08437.10 KIY47527.1 - 6.8 6.9 5.7 1.2 9.3 0.4 2.5 3 0 0 3 3 3 0 Glycosyl transferase family 8 C-terminal Yip1 PF04893.17 KIY47527.1 - 9.1 6.0 13.1 2.1 8.0 9.0 2.0 1 1 1 2 2 2 0 Yip1 domain NTF2 PF02136.20 KIY47528.1 - 1.2e-29 103.4 0.1 1.7e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KIY47528.1 - 6.9e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIY47528.1 - 0.17 11.9 0.0 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Het-C PF07217.11 KIY47529.1 - 3.2e-213 709.3 0.0 4.5e-213 708.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C eIF3_p135 PF12807.7 KIY47529.1 - 0.016 15.3 0.1 0.11 12.6 0.2 2.0 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 TPT PF03151.16 KIY47530.1 - 8.3e-24 84.4 22.3 1.1e-23 84.1 22.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIY47530.1 - 0.0077 16.4 10.6 0.0077 16.4 10.6 2.3 2 0 0 2 2 2 1 EamA-like transporter family TPR_12 PF13424.6 KIY47531.1 - 0.0012 19.1 9.5 6 7.2 0.0 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY47531.1 - 0.0044 17.1 4.2 2.6 8.5 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 KIY47531.1 - 0.014 15.5 0.8 5.6 7.1 0.4 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KIY47531.1 - 0.077 13.1 0.4 3.6 7.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY47531.1 - 0.17 11.7 10.1 12 5.9 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY47531.1 - 0.4 10.9 13.9 17 5.9 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 KIY47532.1 - 2.5e-64 217.2 0.0 2.9e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47532.1 - 2.4e-27 95.9 0.0 3.4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY47532.1 - 7.3e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY47532.1 - 0.00028 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY47532.1 - 0.00076 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY47532.1 - 0.0029 17.6 0.4 1.2 8.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY47532.1 - 0.046 12.6 0.2 0.1 11.5 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain HAD_2 PF13419.6 KIY47533.1 - 1.9e-05 24.8 0.0 0.036 14.2 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY47533.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LSM PF01423.22 KIY47534.1 - 4e-15 55.2 0.1 4.9e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Phage_Arf PF17585.2 KIY47534.1 - 0.0098 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Accessory recombination function protein tRNA-synt_2 PF00152.20 KIY47536.1 - 7.7e-70 235.4 0.0 9.4e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY47536.1 - 2.8e-07 30.4 0.0 5.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WD40 PF00400.32 KIY47537.1 - 4.5e-14 52.6 8.6 7.5e-05 23.4 0.1 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY47537.1 - 3e-06 27.5 0.6 0.76 10.1 0.0 3.9 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain DAHP_synth_2 PF01474.16 KIY47538.1 - 1.3e-61 208.4 0.1 1.4e-30 106.2 0.0 4.0 1 1 3 4 4 4 4 Class-II DAHP synthetase family DEAD PF00270.29 KIY47539.1 - 2.9e-14 53.2 0.0 6.6e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY47539.1 - 8.3e-06 26.1 0.0 2.6e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY47539.1 - 1.7e-05 24.9 0.0 3.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KIY47539.1 - 0.0045 16.3 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain TIP39 PF14980.6 KIY47543.1 - 1.8 8.5 4.6 37 4.3 2.3 2.5 2 0 0 2 2 2 0 TIP39 peptide DUF2345 PF10106.9 KIY47546.1 - 0.022 14.6 5.1 0.2 11.5 5.1 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) IrmA PF18673.1 KIY47546.1 - 0.089 12.9 1.9 43 4.3 0.2 3.9 1 1 1 2 2 2 0 interleukin receptor mimic protein A Ntox14 PF15522.6 KIY47546.1 - 8.6 5.7 6.2 22 4.4 0.4 3.0 1 1 1 2 2 2 0 Novel toxin 14 KDZ PF18758.1 KIY47547.1 - 1.6e-40 139.1 0.2 2.5e-40 138.5 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIY47548.1 - 2e-20 73.3 0.0 3.2e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF4763 PF15960.5 KIY47551.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF1178 PF06676.11 KIY47552.1 - 1.2 9.5 4.5 0.24 11.8 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf-CCHC PF00098.23 KIY47554.1 - 0.0018 18.2 6.1 0.0039 17.2 6.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIY47554.1 - 0.0023 17.7 3.0 0.0023 17.7 3.0 1.8 2 0 0 2 2 2 1 Zinc knuckle Clr5 PF14420.6 KIY47554.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Clr5 domain Paramyx_P_V_C PF03210.13 KIY47554.1 - 0.14 12.0 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal SF3a60_bindingd PF12108.8 KIY47554.1 - 0.17 11.8 1.2 0.31 11.0 1.2 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Clr5 PF14420.6 KIY47555.1 - 0.0046 17.1 0.1 0.012 15.8 0.1 1.7 1 1 0 1 1 1 1 Clr5 domain CD52 PF15116.6 KIY47557.1 - 0.11 12.6 1.1 0.15 12.1 1.1 1.2 1 0 0 1 1 1 0 CAMPATH-1 antigen UDPGT PF00201.18 KIY47558.1 - 1.6e-13 50.3 0.0 2.3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIY47558.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Cellulase PF00150.18 KIY47560.1 - 1e-14 54.7 0.0 1.2e-08 34.8 0.0 3.2 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KIY47560.1 - 6.7e-07 29.8 0.0 1.3e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain F-box-like PF12937.7 KIY47561.1 - 0.071 13.0 0.8 0.19 11.6 0.8 1.7 1 0 0 1 1 1 0 F-box-like Arylsulfotran_2 PF14269.6 KIY47562.1 - 1.2e-39 136.5 0.4 1.8e-39 135.9 0.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY47562.1 - 4.7e-15 55.4 0.0 1.4e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) BAF250_C PF12031.8 KIY47562.1 - 0.24 10.7 0.0 0.47 9.7 0.0 1.4 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Zip PF02535.22 KIY47565.1 - 3.6e-45 154.7 2.5 2e-22 79.9 3.3 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter p450 PF00067.22 KIY47566.1 - 4.2e-66 223.6 0.0 5.2e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med26 PF08711.11 KIY47567.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain adh_short_C2 PF13561.6 KIY47568.1 - 1.3e-17 64.2 0.2 1.8e-17 63.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY47568.1 - 1.3e-12 47.6 0.1 1.8e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY47568.1 - 0.001 19.0 0.1 0.0014 18.6 0.1 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KIY47568.1 - 0.0026 18.3 0.2 0.0054 17.3 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.8 KIY47568.1 - 0.01 15.6 1.2 0.033 14.0 1.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sacchrp_dh_NADP PF03435.18 KIY47568.1 - 0.02 15.1 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PWWP PF00855.17 KIY47569.1 - 1.3e-19 70.4 0.0 1.4e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 PWWP domain GWT1 PF06423.12 KIY47570.1 - 0.091 12.9 0.1 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 GWT1 adh_short PF00106.25 KIY47571.1 - 5.2e-15 55.4 0.8 6.7e-14 51.8 0.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY47571.1 - 3e-11 43.3 2.1 2.5e-09 37.1 2.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY47571.1 - 0.00077 19.4 0.2 0.0013 18.7 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KIY47571.1 - 0.003 18.1 0.2 0.0049 17.4 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.8 KIY47571.1 - 0.0066 16.2 1.4 0.018 14.8 0.8 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sacchrp_dh_NADP PF03435.18 KIY47571.1 - 0.015 15.6 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_24 PF13578.6 KIY47571.1 - 0.062 14.3 0.0 0.088 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Retrotran_gag_2 PF14223.6 KIY47572.1 - 0.019 14.6 0.1 0.023 14.4 0.1 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DDE_Tnp_4 PF13359.6 KIY47575.1 - 5.9e-18 65.0 0.0 8.8e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ABC_membrane PF00664.23 KIY47576.1 - 9.8e-52 176.3 28.8 7.1e-27 94.7 7.9 3.7 4 0 0 4 4 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY47576.1 - 1.6e-44 151.8 0.0 8e-27 94.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KIY47576.1 - 1.5e-11 44.2 6.8 0.0005 19.6 0.4 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY47576.1 - 2e-07 31.6 0.1 0.013 15.9 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KIY47576.1 - 2.3e-06 27.4 0.3 0.074 12.6 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KIY47576.1 - 1.1e-05 25.4 5.2 0.0072 16.2 0.4 4.2 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY47576.1 - 4.5e-05 23.1 0.3 0.062 13.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIY47576.1 - 6.9e-05 23.4 4.4 0.00056 20.5 0.1 2.8 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 KIY47576.1 - 0.00061 19.9 0.2 0.8 9.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 KIY47576.1 - 0.00076 19.6 0.7 0.072 13.2 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KIY47576.1 - 0.0017 18.3 0.2 0.63 9.9 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIY47576.1 - 0.002 18.4 0.6 1.2 9.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KIY47576.1 - 0.0022 17.1 3.9 0.11 11.5 0.0 3.0 2 1 1 3 3 3 1 Type II/IV secretion system protein AAA_7 PF12775.7 KIY47576.1 - 0.0029 17.1 0.1 2 7.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DEAD PF00270.29 KIY47576.1 - 0.0088 15.8 0.2 3.2 7.5 0.1 3.1 3 1 0 3 3 2 1 DEAD/DEAH box helicase AAA_5 PF07728.14 KIY47576.1 - 0.013 15.5 0.1 7.1 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 KIY47576.1 - 0.016 14.5 0.6 1.8 7.8 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 KIY47576.1 - 0.031 13.1 0.6 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein Dynamin_N PF00350.23 KIY47576.1 - 0.031 14.3 0.6 3.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 KIY47576.1 - 0.069 12.9 0.0 3.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 KIY47576.1 - 0.073 13.5 0.3 2.7 8.4 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIY47576.1 - 0.11 12.3 0.0 19 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIY47576.1 - 0.13 12.5 0.1 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PhoH PF02562.16 KIY47576.1 - 0.14 11.6 0.1 8.1 5.8 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Pox_A32 PF04665.12 KIY47576.1 - 0.15 11.4 1.6 13 5.2 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.17 KIY47576.1 - 0.16 11.7 1.3 18 5.0 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 KIY47576.1 - 0.17 11.6 0.1 0.61 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 KIY47576.1 - 0.21 11.4 0.7 1.3 8.9 0.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea cobW PF02492.19 KIY47576.1 - 0.74 9.4 2.8 2.5 7.7 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CBM_21 PF03370.13 KIY47578.1 - 1.4e-19 70.3 0.0 3.5e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) Methyltransf_12 PF08242.12 KIY47578.1 - 0.1 13.4 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CBM53 PF16760.5 KIY47578.1 - 0.18 12.4 0.0 0.76 10.4 0.0 2.1 1 1 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) MFS_1 PF07690.16 KIY47579.1 - 1e-16 60.8 49.5 1.7e-14 53.5 24.1 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY47579.1 - 0.00067 18.2 2.1 0.00067 18.2 2.1 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) S1FA PF04689.13 KIY47579.1 - 0.083 13.0 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 DNA binding protein S1FA DUF2976 PF11190.8 KIY47579.1 - 1.2 9.0 6.2 5.6 6.8 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) gag_pre-integrs PF13976.6 KIY47580.1 - 0.0024 17.7 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Clr5 PF14420.6 KIY47581.1 - 0.03 14.6 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain gag-asp_proteas PF13975.6 KIY47582.1 - 4.5e-05 23.9 0.0 0.00027 21.4 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY47582.1 - 0.0052 17.4 0.0 0.012 16.2 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease 3Beta_HSD PF01073.19 KIY47587.1 - 2.2e-52 177.8 0.0 4.9e-52 176.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIY47587.1 - 3.7e-32 111.7 0.0 4.6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KIY47587.1 - 1.1e-16 60.8 0.0 1.7e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KIY47587.1 - 8.7e-14 51.3 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KIY47587.1 - 1.8e-13 50.6 0.0 5.2e-12 45.8 0.0 2.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIY47587.1 - 2.2e-13 50.5 0.0 3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIY47587.1 - 1e-05 24.8 2.0 0.0004 19.6 0.1 2.6 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIY47587.1 - 0.0013 18.3 0.1 0.0051 16.4 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 KIY47587.1 - 0.0024 17.8 0.1 0.0055 16.6 0.1 1.7 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIY47587.1 - 0.0074 16.5 0.2 0.024 14.9 0.2 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KIY47587.1 - 0.034 13.6 0.2 0.09 12.2 0.2 1.9 1 1 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 KIY47587.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.7 1 1 0 1 1 1 0 TrkA-N domain Mur_ligase PF01225.25 KIY47587.1 - 0.21 11.9 0.4 6.6 7.1 0.6 2.5 1 1 1 2 2 2 0 Mur ligase family, catalytic domain Ldh_1_N PF00056.23 KIY47588.1 - 1.5e-46 158.0 0.1 2e-46 157.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KIY47588.1 - 2.5e-45 154.4 0.0 4.5e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KIY47588.1 - 2.6e-05 23.4 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIY47588.1 - 0.0079 16.6 0.1 0.027 14.9 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 KIY47588.1 - 0.097 12.2 0.1 2.3 7.7 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase AAA PF00004.29 KIY47589.1 - 2e-19 70.4 0.0 3.7e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY47589.1 - 0.0013 19.1 0.0 0.15 12.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KIY47589.1 - 0.008 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KIY47589.1 - 0.016 15.3 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIY47589.1 - 0.034 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIY47589.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 KIY47589.1 - 0.08 13.3 0.0 0.35 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KIY47589.1 - 0.1 12.6 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIY47589.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DSS1_SEM1 PF05160.13 KIY47589.1 - 6.6 6.9 7.6 1 9.4 3.8 1.6 2 0 0 2 2 2 0 DSS1/SEM1 family HMG_box_2 PF09011.10 KIY47590.1 - 2.9e-18 66.2 1.7 3.6e-18 65.9 1.7 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KIY47590.1 - 1.4e-17 63.9 1.4 1.7e-17 63.6 1.4 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box CHDNT PF08073.12 KIY47590.1 - 0.02 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain AAA_11 PF13086.6 KIY47591.1 - 1.5e-62 211.7 0.0 2.2e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KIY47591.1 - 2.2e-57 193.9 0.0 3.3e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIY47591.1 - 4.3e-10 39.7 0.0 0.014 15.1 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIY47591.1 - 1.6e-09 37.8 0.0 6.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIY47591.1 - 2.7e-08 34.3 0.0 4.8e-07 30.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain ResIII PF04851.15 KIY47591.1 - 0.00016 21.8 0.0 0.0033 17.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY47591.1 - 0.00043 20.6 0.0 0.011 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KIY47591.1 - 0.00077 19.2 0.1 0.012 15.4 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KIY47591.1 - 0.0008 18.8 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KIY47591.1 - 0.0038 16.7 0.0 1.3 8.4 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein AAA PF00004.29 KIY47591.1 - 0.011 16.2 0.2 0.059 13.8 0.1 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIY47591.1 - 0.012 15.3 0.0 1.6 8.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KIY47591.1 - 0.014 14.9 0.0 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KIY47591.1 - 0.058 12.9 0.0 0.19 11.2 0.0 1.9 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KIY47591.1 - 0.072 13.5 0.1 0.18 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KIY47591.1 - 0.099 12.8 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KIY47591.1 - 0.18 11.6 0.0 1.2 8.8 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase STE2 PF02116.15 KIY47592.1 - 4.5e-05 22.9 23.2 0.00013 21.4 23.0 1.7 1 1 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Phage_holin_8 PF16931.5 KIY47592.1 - 0.13 12.2 2.8 6.2 6.8 0.2 2.6 2 0 0 2 2 2 0 Putative phage holin S36_mt PF10937.8 KIY47593.1 - 5.6e-11 44.0 0.4 2.3e-08 35.6 0.4 2.1 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial Succ_CoA_lig PF13607.6 KIY47593.1 - 0.076 12.8 0.2 0.13 12.1 0.1 1.4 1 1 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain DUF5470 PF17564.2 KIY47593.1 - 1.3 9.3 3.2 8.8 6.6 0.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5470) ATG13 PF10033.9 KIY47595.1 - 7.6e-33 114.2 0.1 9.2e-33 113.9 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 13 MIF4G_like PF09088.11 KIY47596.1 - 7.7e-55 185.6 0.0 3.4e-54 183.5 0.0 2.0 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 KIY47596.1 - 3.8e-54 183.9 0.0 5.5e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 MIF4G like Glyco_hydro_16 PF00722.21 KIY47597.1 - 0.0019 17.7 0.1 0.0064 16.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Col_cuticle_N PF01484.17 KIY47597.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Muted PF14942.6 KIY47598.1 - 0.066 13.6 0.9 0.12 12.8 0.9 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Actin PF00022.19 KIY47599.1 - 4.4e-147 489.9 0.0 2.7e-146 487.4 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 KIY47599.1 - 0.13 10.8 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Med31 PF05669.12 KIY47601.1 - 0.019 15.0 4.7 0.054 13.5 4.7 1.9 1 1 0 1 1 1 0 SOH1 ABC_membrane PF00664.23 KIY47602.1 - 0.0063 16.2 0.0 0.0063 16.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Plavaka PF18759.1 KIY47605.1 - 1.3e-77 261.3 6.3 7.7e-62 209.4 0.1 3.2 1 1 1 2 2 2 2 Plavaka transposase Cdc6_C PF09079.11 KIY47606.1 - 1 9.4 11.3 22 5.1 1.4 3.4 1 1 2 3 3 3 0 CDC6, C terminal winged helix domain V-ATPase_H_N PF03224.14 KIY47607.1 - 0.087 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H Phasin_2 PF09361.10 KIY47607.1 - 0.11 12.8 4.6 0.29 11.4 4.6 1.7 1 0 0 1 1 1 0 Phasin protein NODP PF07684.12 KIY47611.1 - 0.14 12.3 0.9 0.36 11.0 0.9 1.7 1 0 0 1 1 1 0 NOTCH protein rve PF00665.26 KIY47613.1 - 0.17 12.0 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain TPR_17 PF13431.6 KIY47615.1 - 0.021 15.2 0.1 0.77 10.3 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY47615.1 - 0.024 14.8 0.3 5 7.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY47615.1 - 0.067 13.1 1.4 1.6 8.7 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY47615.1 - 0.12 12.5 0.9 5.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Integrase_H2C2 PF17921.1 KIY47616.1 - 2.8e-07 30.5 1.7 3.3e-07 30.3 0.5 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain SusD-like PF12741.7 KIY47616.1 - 0.099 11.5 0.2 0.15 10.9 0.2 1.2 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein Myb_DNA-bind_2 PF08914.11 KIY47618.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 Rap1 Myb domain DUF3269 PF11673.8 KIY47619.1 - 0.012 16.0 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) Sec23_BS PF08033.12 KIY47620.1 - 1.5e-07 32.1 0.0 2.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KIY47620.1 - 0.026 14.3 0.3 0.057 13.2 0.3 1.6 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Lactamase_B_2 PF12706.7 KIY47621.1 - 1.6e-08 34.3 0.1 2.4e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 KIY47621.1 - 3.8e-05 22.8 4.0 0.0001 21.4 4.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily FNIP_C PF14638.6 KIY47622.1 - 0.071 12.7 0.1 0.091 12.4 0.1 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Adap_comp_sub PF00928.21 KIY47623.1 - 2.2e-15 56.7 0.1 2.6e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF4413 PF14372.6 KIY47626.1 - 0.0084 16.5 0.5 0.015 15.6 0.3 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4413) BP28CT PF08146.12 KIY47627.1 - 3.3e-18 66.0 0.1 8e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 BP28CT (NUC211) domain Ribonucleas_3_3 PF14622.6 KIY47628.1 - 1.2e-18 67.5 0.0 3.2e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIY47628.1 - 0.018 15.6 0.0 0.03 14.9 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III domain IBR PF01485.21 KIY47629.1 - 1.2e-15 57.5 32.9 1.4e-10 41.2 5.3 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KIY47629.1 - 5.1e-07 29.6 5.0 5.1e-07 29.6 5.0 3.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY47629.1 - 1.4e-06 28.0 4.7 1.4e-06 28.0 4.7 4.2 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY47629.1 - 1.6e-05 24.9 6.4 1.6e-05 24.9 6.4 4.0 3 2 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIY47629.1 - 0.00017 21.3 4.7 0.00017 21.3 4.7 3.8 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY47629.1 - 0.00022 21.0 3.4 0.00022 21.0 3.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY47629.1 - 0.00034 20.9 5.1 0.00034 20.9 5.1 3.7 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KIY47629.1 - 0.0047 16.9 4.9 0.0047 16.9 4.9 3.7 3 1 0 3 3 3 1 zinc-RING finger domain Vps35 PF03635.17 KIY47630.1 - 0 1023.5 0.0 0 1023.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 40S_SA_C PF16122.5 KIY47630.1 - 0.11 13.9 10.8 0.33 12.3 10.1 2.1 2 0 0 2 2 2 0 40S ribosomal protein SA C-terminus TAF4 PF05236.14 KIY47630.1 - 0.19 11.4 2.9 0.23 11.2 1.7 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family PHD PF00628.29 KIY47631.1 - 0.12 12.3 2.7 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 PHD-finger Suc_Fer-like PF06999.12 KIY47632.1 - 7.2e-11 42.3 0.0 3.3e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Sucrase/ferredoxin-like RNA_pol_I_A49 PF06870.12 KIY47633.1 - 2.3e-103 346.0 0.1 2.7e-103 345.8 0.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SRI PF08236.11 KIY47634.1 - 4.9e-18 65.1 13.9 4.9e-18 65.1 13.9 2.8 2 1 1 3 3 3 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KIY47634.1 - 1.8e-16 61.0 0.2 1.8e-16 61.0 0.2 3.8 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KIY47634.1 - 3.9e-13 49.2 8.1 3.9e-13 49.2 8.1 1.8 2 0 0 2 2 2 1 AWS domain Rrf2 PF02082.20 KIY47634.1 - 0.66 10.4 2.8 0.64 10.4 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator AAA_12 PF13087.6 KIY47635.1 - 1e-55 188.5 0.0 1.6e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY47635.1 - 1.1e-25 91.0 1.4 1.8e-20 73.8 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 KIY47635.1 - 7.9e-12 45.7 0.1 6.4e-11 42.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY47635.1 - 1.6e-09 37.7 0.0 3.1e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KIY47635.1 - 7.3e-07 29.0 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KIY47635.1 - 0.0027 17.5 0.0 2.6 7.7 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KIY47635.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3761 PF12587.8 KIY47636.1 - 2.3 8.7 7.7 0.44 11.0 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3761) CRAL_TRIO PF00650.20 KIY47637.1 - 6.1e-21 74.8 0.0 8.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY47637.1 - 1e-07 32.0 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CUE PF02845.16 KIY47638.1 - 0.00048 19.8 0.0 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 CUE domain APH PF01636.23 KIY47639.1 - 9.3e-18 65.0 0.0 1.3e-17 64.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY47639.1 - 2.5e-05 24.0 0.0 3.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIY47639.1 - 0.088 12.4 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KIY47639.1 - 0.13 11.6 0.0 0.83 9.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIY47639.1 - 0.15 11.4 0.0 0.44 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Arylsulfotran_2 PF14269.6 KIY47640.1 - 7.4e-59 199.6 3.1 1e-58 199.1 3.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY47640.1 - 1.8e-13 50.2 1.3 2.5e-12 46.4 1.3 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 KIY47640.1 - 0.0019 18.1 0.9 12 6.1 0.0 4.1 3 0 0 3 3 3 2 PQQ enzyme repeat DUF3472 PF11958.8 KIY47640.1 - 0.0065 17.0 1.5 0.013 16.0 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) RHS PF03527.14 KIY47640.1 - 0.23 11.3 4.2 27 4.6 0.0 4.5 5 0 0 5 5 5 0 RHS protein EphA2_TM PF14575.6 KIY47641.1 - 0.017 16.0 0.0 0.035 15.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2561 PF10812.8 KIY47641.1 - 0.039 14.0 0.1 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Ni_hydr_CYTB PF01292.20 KIY47641.1 - 0.044 13.4 0.2 0.065 12.8 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF998 PF06197.13 KIY47641.1 - 0.06 12.9 1.3 0.084 12.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF2632 PF10943.8 KIY47641.1 - 0.12 12.0 3.1 0.16 11.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) GP41 PF00517.17 KIY47641.1 - 0.17 11.8 2.0 0.24 11.3 2.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein RCR PF12273.8 KIY47641.1 - 0.19 12.4 16.4 1.6 9.4 16.4 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF5408 PF17402.2 KIY47641.1 - 0.25 11.3 0.8 0.5 10.3 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5408) Synaptobrevin PF00957.21 KIY47641.1 - 1 9.2 3.3 1.6 8.6 3.3 1.3 1 0 0 1 1 1 0 Synaptobrevin Hamartin PF04388.12 KIY47641.1 - 2.2 6.8 7.9 2.8 6.5 7.9 1.1 1 0 0 1 1 1 0 Hamartin protein RCR PF12273.8 KIY47642.1 - 0.00076 20.1 31.0 0.001 19.7 11.9 2.4 2 0 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red DUF350 PF03994.14 KIY47642.1 - 0.091 12.9 1.5 0.17 12.1 1.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) Bromo_TP PF07524.13 KIY47643.1 - 3.5e-07 30.1 0.0 6.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.6 KIY47643.1 - 0.017 15.5 8.0 0.017 15.5 8.0 2.2 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DAHP_synth_1 PF00793.20 KIY47644.1 - 4.1e-88 294.8 0.0 6.1e-88 294.3 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family zinc_ribbon_16 PF17034.5 KIY47644.1 - 0.092 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family SICA_beta PF12878.7 KIY47644.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 SICA extracellular beta domain GAT PF03127.14 KIY47645.1 - 1.9e-05 24.9 0.6 0.0051 17.1 0.6 2.3 1 1 1 2 2 2 2 GAT domain DUF3327 PF11806.8 KIY47645.1 - 0.077 13.7 0.0 0.091 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) F-box-like PF12937.7 KIY47646.1 - 5e-05 23.1 0.1 9.6e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY47646.1 - 0.00078 19.3 0.0 0.0031 17.4 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KIY47646.1 - 0.0019 18.1 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 F-box Myb_DNA-bind_3 PF12776.7 KIY47647.1 - 3.9e-06 27.7 0.5 2e-05 25.5 0.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain NinF PF05810.12 KIY47647.1 - 0.015 15.2 1.4 0.034 14.0 1.4 1.6 1 0 0 1 1 1 0 NinF protein Myb_DNA-bind_4 PF13837.6 KIY47647.1 - 0.063 13.7 0.0 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 KIY47648.1 - 0.00023 20.9 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5308 PF17233.2 KIY47650.1 - 0.046 13.9 0.0 0.049 13.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SapB_2 PF03489.17 KIY47650.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Saposin-like type B, region 2 IMPDH PF00478.25 KIY47653.1 - 4e-128 427.2 0.0 2.5e-126 421.4 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KIY47653.1 - 2.4e-11 43.9 0.1 2.4e-06 27.9 0.0 2.9 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 KIY47653.1 - 3.7e-10 39.4 0.9 6.1e-10 38.6 0.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KIY47653.1 - 9.6e-08 31.8 7.8 6.1e-07 29.1 5.4 2.4 2 1 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KIY47653.1 - 1.5e-05 24.6 3.7 0.00013 21.5 0.8 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KIY47653.1 - 0.00012 21.5 1.2 0.00021 20.7 0.8 1.6 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KIY47653.1 - 0.00093 18.4 1.7 0.024 13.8 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF561) Dus PF01207.17 KIY47653.1 - 0.1 11.6 1.9 0.68 9.0 0.2 2.2 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 KIY47653.1 - 0.25 10.8 1.5 3.4 7.1 0.2 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator 2-Hacid_dh_C PF02826.19 KIY47654.1 - 4.5e-33 114.1 0.0 4.4e-32 110.9 0.1 2.3 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY47654.1 - 5e-21 74.8 0.0 6.3e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY47654.1 - 0.0041 17.3 0.0 0.0074 16.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIY47654.1 - 0.04 14.5 0.0 0.086 13.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF588 PF04535.12 KIY47654.1 - 0.04 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) eIF-5a PF01287.20 KIY47655.1 - 4.4e-31 106.8 0.5 6.5e-31 106.3 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KIY47655.1 - 0.041 13.9 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain LIM PF00412.22 KIY47656.1 - 1.4e-22 79.7 24.4 2.6e-11 43.5 7.4 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 KIY47656.1 - 0.044 13.4 21.6 0.47 10.1 0.6 5.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KIY47656.1 - 0.051 13.7 18.0 0.33 11.1 2.2 4.1 4 0 0 4 4 4 0 Zinc ribbon domain DUF5604 PF18300.1 KIY47656.1 - 0.14 12.2 0.0 17 5.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5604) Cytochrome_C7 PF14522.6 KIY47656.1 - 5.4 7.1 23.2 40 4.3 17.6 3.1 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c AA_permease PF00324.21 KIY47657.1 - 5.9e-123 411.0 38.7 8.3e-123 410.5 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY47657.1 - 2.9e-34 118.6 42.9 3.7e-34 118.3 42.9 1.1 1 0 0 1 1 1 1 Amino acid permease Amidohydro_2 PF04909.14 KIY47660.1 - 1e-15 58.3 0.3 2.9e-15 56.8 0.1 1.7 2 0 0 2 2 2 1 Amidohydrolase Alanine_zipper PF11839.8 KIY47662.1 - 2.3e-05 24.7 10.1 2.3e-05 24.7 10.1 1.9 2 0 0 2 2 2 1 Alanine-zipper, major outer membrane lipoprotein T3SSipB PF16535.5 KIY47662.1 - 0.0088 16.5 2.7 0.0088 16.5 2.7 2.1 2 0 0 2 2 2 1 Type III cell invasion protein SipB XhlA PF10779.9 KIY47662.1 - 0.096 12.9 4.2 0.71 10.1 3.1 2.4 1 1 2 3 3 3 0 Haemolysin XhlA Tropomyosin PF00261.20 KIY47662.1 - 0.14 11.5 9.1 0.28 10.5 9.1 1.5 1 1 0 1 1 1 0 Tropomyosin Tri3 PF07428.11 KIY47663.1 - 0.00026 20.1 0.1 0.00054 19.0 0.1 1.5 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 RCC1 PF00415.18 KIY47664.1 - 8.5e-60 199.2 16.6 8.9e-11 42.3 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY47664.1 - 7.5e-39 130.8 40.4 2e-08 33.8 0.5 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat DSPc PF00782.20 KIY47665.1 - 7.9e-11 41.9 0.0 8.2e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY47665.1 - 0.015 14.8 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KIY47665.1 - 0.066 13.2 0.0 0.077 13.0 0.0 1.0 1 0 0 1 1 1 0 Tyrosine phosphatase family PAP_assoc PF03828.19 KIY47666.1 - 6e-16 58.4 0.2 1.3e-15 57.4 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIY47666.1 - 5.7e-05 23.3 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIY47666.1 - 0.011 15.9 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase ATP11 PF06644.11 KIY47667.1 - 2.2e-75 253.9 0.2 2.5e-75 253.8 0.2 1.0 1 0 0 1 1 1 1 ATP11 protein CTP_transf_like PF01467.26 KIY47668.1 - 1.6e-25 89.9 0.0 2.4e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF3363 PF11843.8 KIY47668.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) EphA2_TM PF14575.6 KIY47669.1 - 0.0016 19.3 0.0 0.0024 18.7 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Vpu PF00558.19 KIY47669.1 - 0.093 12.5 0.4 0.18 11.6 0.4 1.4 1 0 0 1 1 1 0 Vpu protein PPDFL PF15060.6 KIY47670.1 - 0.036 14.6 1.1 0.065 13.8 1.1 1.3 1 0 0 1 1 1 0 Differentiation and proliferation regulator DUF2975 PF11188.8 KIY47670.1 - 0.39 10.6 6.1 0.2 11.5 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF515 PF04415.12 KIY47670.1 - 0.5 8.7 3.1 0.78 8.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF4834 PF16118.5 KIY47670.1 - 0.64 11.0 2.8 5.3 8.1 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 KIY47671.1 - 6.6e-59 199.4 0.0 1.1e-26 93.8 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KIY47671.1 - 5.4e-43 147.4 0.0 5.2e-41 140.9 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KIY47671.1 - 5.6e-29 101.2 0.0 1.5e-10 40.8 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KIY47671.1 - 8.1e-14 51.9 0.2 3.3e-13 49.9 0.1 2.2 2 0 0 2 2 2 1 RWD domain Afi1 PF07792.12 KIY47671.1 - 0.033 14.7 2.3 0.048 14.2 0.1 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pkinase_fungal PF17667.1 KIY47671.1 - 0.35 9.6 0.0 0.35 9.6 0.0 1.9 3 0 0 3 3 3 0 Fungal protein kinase tRNA-synt_1 PF00133.22 KIY47672.1 - 1.6e-151 505.6 0.0 2.1e-151 505.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIY47672.1 - 6.7e-22 78.1 0.2 1.4e-21 77.1 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIY47672.1 - 1.4e-17 63.6 0.1 3.4e-10 39.2 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KIY47672.1 - 0.029 13.7 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain RecR PF02132.15 KIY47672.1 - 0.084 12.5 0.3 0.19 11.4 0.3 1.5 1 0 0 1 1 1 0 RecR protein DUF945 PF06097.11 KIY47672.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) zf-FPG_IleRS PF06827.14 KIY47672.1 - 1.2 9.1 7.8 4.5 7.2 7.8 2.0 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Aldedh PF00171.22 KIY47673.1 - 6.2e-115 384.3 0.0 7.3e-115 384.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4770 PF15994.5 KIY47675.1 - 3.7 7.7 17.9 1.2 9.4 4.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4770) RNA_pol_Rpb2_6 PF00562.28 KIY47676.1 - 1e-121 406.7 0.0 1.4e-121 406.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIY47676.1 - 1e-55 188.4 0.1 3.6e-55 186.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KIY47676.1 - 5.7e-33 113.2 0.1 1.6e-32 111.7 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KIY47676.1 - 2.3e-31 108.9 0.0 7.4e-31 107.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KIY47676.1 - 2.2e-26 91.9 2.7 3.9e-26 91.1 1.6 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KIY47676.1 - 2e-20 72.7 0.0 5.4e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KIY47676.1 - 1.9e-10 41.2 1.5 1.9e-10 41.2 1.5 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 5 FAD_binding_3 PF01494.19 KIY47677.1 - 8.7e-60 202.8 0.0 1.1e-59 202.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY47677.1 - 0.006 15.9 0.1 0.33 10.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY47677.1 - 0.03 13.9 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY47677.1 - 0.037 14.3 0.6 0.14 12.4 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY47677.1 - 0.13 11.4 0.0 0.5 9.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-CCCH_2 PF14608.6 KIY47678.1 - 0.39 11.3 3.9 0.92 10.1 3.9 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger SMC_N PF02463.19 KIY47680.1 - 5.4e-70 235.3 0.0 8.3e-70 234.6 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIY47680.1 - 3.2e-17 62.9 0.0 2e-16 60.3 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIY47680.1 - 1e-13 51.8 8.5 8.5e-07 29.1 0.4 3.3 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIY47680.1 - 3.4e-13 50.0 34.7 4.4e-11 43.1 4.5 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KIY47680.1 - 4.6e-10 40.3 29.9 4.6e-10 40.3 29.9 5.4 3 2 0 3 3 2 1 AAA domain Spc7 PF08317.11 KIY47680.1 - 0.0018 17.2 7.7 0.0018 17.2 7.7 6.9 3 2 4 7 7 7 2 Spc7 kinetochore protein AAA_29 PF13555.6 KIY47680.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIY47680.1 - 0.017 15.2 0.8 0.22 11.6 0.8 3.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KIY47680.1 - 0.24 10.7 0.0 0.24 10.7 0.0 3.9 5 0 0 5 5 5 0 FtsK/SpoIIIE family TcdB_N PF12918.7 KIY47680.1 - 0.72 10.2 4.3 13 6.1 0.0 4.3 4 0 0 4 4 4 0 TcdB toxin N-terminal helical domain ABC_tran PF00005.27 KIY47680.1 - 1.4 9.5 0.0 1.4 9.5 0.0 5.7 3 2 0 3 3 3 0 ABC transporter TRAF_BIRC3_bd PF16673.5 KIY47680.1 - 2 8.3 8.6 2.6 7.9 1.0 4.6 3 2 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF87 PF01935.17 KIY47680.1 - 2.6 8.1 0.0 2.6 8.1 0.0 5.6 4 1 1 6 6 6 0 Helicase HerA, central domain Oxysterol_BP PF01237.18 KIY47681.1 - 2.2e-123 411.8 0.0 3.2e-123 411.3 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 KIY47681.1 - 1.1e-10 41.5 0.0 7.8e-07 29.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY47681.1 - 1.8e-09 38.0 0.1 4.1e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH PF00169.29 KIY47681.1 - 3.4e-08 33.9 0.0 8.6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Ank PF00023.30 KIY47681.1 - 1.5e-07 31.5 0.4 0.0029 18.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIY47681.1 - 1.8e-07 30.9 0.3 0.063 13.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KIY47681.1 - 4.1e-06 27.2 0.1 0.0015 19.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) PH_11 PF15413.6 KIY47681.1 - 1e-05 25.9 0.3 2.2e-05 24.8 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KIY47681.1 - 0.00018 21.7 2.3 0.00043 20.5 0.5 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain KfrA_N PF11740.8 KIY47681.1 - 0.43 11.3 0.0 0.43 11.3 0.0 2.7 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term MFS_1 PF07690.16 KIY47682.1 - 2.7e-16 59.5 34.5 3.8e-16 59.0 34.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0016 PF01169.19 KIY47683.1 - 1.1e-40 137.8 15.3 2.1e-20 72.8 3.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 FAM70 PF14967.6 KIY47683.1 - 0.005 16.4 1.4 0.35 10.3 0.1 2.1 2 0 0 2 2 2 2 FAM70 protein Mntp PF02659.15 KIY47683.1 - 0.013 15.2 0.2 0.013 15.2 0.2 2.3 2 0 0 2 2 2 0 Putative manganese efflux pump DUF3995 PF13160.6 KIY47683.1 - 0.12 12.8 9.5 0.31 11.4 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) LysE PF01810.18 KIY47683.1 - 0.29 10.6 12.4 0.82 9.1 3.8 2.5 2 0 0 2 2 2 0 LysE type translocator TerC PF03741.16 KIY47683.1 - 2 8.1 9.9 0.11 12.2 3.1 2.1 2 1 0 2 2 2 0 Integral membrane protein TerC family TauE PF01925.19 KIY47683.1 - 7.6 6.1 17.4 2.5e+02 1.1 17.4 2.1 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE CFEM PF05730.11 KIY47684.1 - 0.00062 19.8 10.0 0.0014 18.7 10.0 1.6 1 0 0 1 1 1 1 CFEM domain DUF3740 PF12548.8 KIY47684.1 - 0.5 10.8 5.0 0.31 11.5 0.6 2.0 2 0 0 2 2 2 0 Sulfatase protein EST1 PF10374.9 KIY47684.1 - 0.56 10.9 6.9 0.48 11.1 0.6 2.1 2 0 0 2 2 2 0 Telomerase activating protein Est1 SPX PF03105.19 KIY47684.1 - 1.2 8.9 11.7 1.6 8.6 11.7 1.1 1 0 0 1 1 1 0 SPX domain DNA_ligase_A_M PF01068.21 KIY47685.1 - 8.8e-50 169.2 0.0 3.5e-49 167.2 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIY47685.1 - 1.3e-38 133.0 0.1 5.6e-38 131.0 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 KIY47685.1 - 3.4e-21 75.5 0.1 5.1e-09 36.4 0.0 3.5 3 1 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KIY47685.1 - 3.8e-13 49.9 0.0 2.6e-12 47.2 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KIY47685.1 - 1.4e-12 48.2 0.0 2.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KIY47685.1 - 0.001 19.4 0.1 3 8.3 0.0 3.7 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain DUF4073 PF13285.6 KIY47685.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4073) RTT107_BRCT_5 PF16770.5 KIY47685.1 - 0.013 15.4 0.1 6.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KIY47685.1 - 0.047 14.0 0.0 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain MREG PF15812.5 KIY47685.1 - 0.059 13.7 0.1 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Melanoregulin Amidase PF01425.21 KIY47686.1 - 5.7e-84 282.7 0.0 6.8e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Amidase ABC_tran PF00005.27 KIY47688.1 - 1.4e-44 151.9 0.0 6.1e-25 88.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY47688.1 - 1.1e-18 67.9 11.9 6.2e-10 39.2 1.4 3.6 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_22 PF13401.6 KIY47688.1 - 3.7e-06 27.3 4.2 0.0069 16.7 0.0 3.8 4 1 0 4 4 4 2 AAA domain SMC_N PF02463.19 KIY47688.1 - 3.9e-06 26.5 0.6 0.0078 15.7 0.6 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY47688.1 - 0.0007 19.5 0.7 0.078 12.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIY47688.1 - 0.0013 18.7 1.1 0.43 10.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KIY47688.1 - 0.0047 16.5 0.7 3.1 7.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KIY47688.1 - 0.009 16.1 0.2 0.009 16.1 0.2 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 KIY47688.1 - 0.035 14.3 0.2 2.8 8.2 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KIY47688.1 - 0.035 14.5 0.5 1.5 9.2 0.1 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KIY47688.1 - 0.058 13.5 0.3 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY47688.1 - 0.064 12.6 1.9 0.7 9.2 0.3 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KIY47688.1 - 0.069 12.9 4.0 0.22 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KIY47688.1 - 0.08 13.0 0.1 22 5.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KIY47688.1 - 0.14 11.8 0.6 10 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIY47688.1 - 0.18 10.8 1.5 6 5.8 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 KIY47688.1 - 0.2 11.2 5.3 0.074 12.6 1.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KIY47688.1 - 0.22 11.3 2.2 8.4 6.2 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 KIY47688.1 - 0.33 11.4 1.5 12 6.4 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIY47688.1 - 0.71 10.3 3.6 22 5.5 0.7 2.3 2 0 0 2 2 2 0 AAA domain DIOX_N PF14226.6 KIY47689.1 - 2.2e-26 92.9 0.0 3.6e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY47689.1 - 5.8e-16 58.8 0.0 9.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 KIY47690.1 - 1.7e-80 271.0 31.0 1.9e-80 270.8 31.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Dabb PF07876.12 KIY47691.1 - 4.2e-15 56.2 0.6 4.5e-15 56.0 0.6 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1330 PF07045.11 KIY47691.1 - 0.066 13.6 0.1 0.091 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Glyco_hydro_3 PF00933.21 KIY47692.1 - 4.7e-77 259.5 0.0 5.4e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Peptidase_S10 PF00450.22 KIY47693.1 - 4.9e-73 246.9 0.1 1.1e-72 245.7 0.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase APH PF01636.23 KIY47694.1 - 6.7e-12 45.8 0.0 3.3e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family APOBEC1 PF18769.1 KIY47694.1 - 0.1 12.8 0.1 0.28 11.5 0.1 1.7 1 0 0 1 1 1 0 APOBEC1 PhoLip_ATPase_C PF16212.5 KIY47695.1 - 2.3e-74 250.3 34.4 2.3e-74 250.3 34.4 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 KIY47695.1 - 2.4e-12 46.8 0.0 5.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIY47695.1 - 2.8e-12 47.4 0.0 2e-06 28.2 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 KIY47695.1 - 3.3e-12 45.9 0.3 8.3e-12 44.6 0.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KIY47695.1 - 9e-06 25.3 3.4 1.9e-05 24.3 0.0 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIY47695.1 - 0.0075 16.0 0.1 0.049 13.4 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 KIY47696.1 - 9.4e-07 28.6 0.0 3.2e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY47696.1 - 0.00022 21.2 0.7 0.0017 18.3 0.0 2.5 3 1 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIY47696.1 - 0.0012 18.9 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3584 PF12128.8 KIY47696.1 - 0.027 12.0 4.1 0.034 11.7 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) XFP PF03894.15 KIY47696.1 - 0.029 14.1 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase GRP PF07172.11 KIY47697.1 - 0.0069 17.0 3.8 0.0069 17.0 3.8 3.1 2 1 0 2 2 2 1 Glycine rich protein family OppC_N PF12911.7 KIY47697.1 - 0.016 15.1 0.3 0.04 13.9 0.3 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Amnionless PF14828.6 KIY47697.1 - 0.094 11.5 3.6 0.037 12.9 1.0 1.5 1 1 1 2 2 2 0 Amnionless SAD_SRA PF02182.17 KIY47698.1 - 1e-39 135.8 0.3 1.2e-39 135.5 0.3 1.1 1 0 0 1 1 1 1 SAD/SRA domain DUF3583 PF12126.8 KIY47698.1 - 0.032 13.7 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Kunitz_BPTI PF00014.23 KIY47698.1 - 0.13 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain GMP_synt_C PF00958.22 KIY47699.1 - 1.6e-45 153.1 0.1 3e-45 152.2 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KIY47699.1 - 1.3e-36 126.2 0.0 2.2e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIY47699.1 - 2.8e-10 40.3 0.0 5.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 KIY47699.1 - 3.8e-10 39.3 0.1 7.7e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.14 KIY47699.1 - 0.00069 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 KIY47699.1 - 0.00072 18.5 0.1 0.0011 17.9 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Arginosuc_synth PF00764.19 KIY47699.1 - 0.0073 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KIY47699.1 - 0.06 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 KIY47699.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family MetJ PF01340.20 KIY47699.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Met Apo-repressor, MetJ CAP PF00188.26 KIY47700.1 - 0.0062 17.4 0.3 0.0092 16.8 0.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family UbiA PF01040.18 KIY47701.1 - 1.7e-58 197.9 18.5 2.5e-58 197.3 18.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family F-box-like PF12937.7 KIY47702.1 - 0.011 15.6 0.6 0.011 15.6 0.6 2.2 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KIY47702.1 - 0.063 13.2 0.2 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 F-box domain PROL5-SMR PF15621.6 KIY47703.1 - 0.23 12.0 4.4 0.36 11.4 2.9 2.1 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF3449 PF11931.8 KIY47704.1 - 2.7e-08 33.8 0.0 4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) HTH_21 PF13276.6 KIY47705.1 - 1.5e-05 25.0 0.9 0.0032 17.6 0.0 2.9 3 0 0 3 3 3 2 HTH-like domain Alpha_kinase PF02816.18 KIY47707.1 - 1.4e-28 100.2 0.1 2.8e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 Alpha-kinase family Zn-ribbon_8 PF09723.10 KIY47707.1 - 0.2 11.8 4.4 1.1 9.4 0.3 2.8 2 0 0 2 2 2 0 Zinc ribbon domain DUF1064 PF06356.11 KIY47707.1 - 0.2 12.0 0.1 0.42 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) DZR PF12773.7 KIY47707.1 - 0.42 10.7 3.8 17 5.6 1.7 2.9 1 1 1 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.16 KIY47707.1 - 7.8 6.7 5.7 30 4.9 0.5 3.3 2 1 1 3 3 3 0 FYVE-type zinc finger DNA_pol_B PF00136.21 KIY47708.1 - 3.3e-13 49.2 0.0 2.8e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase family B ATP-synt_ab PF00006.25 KIY47709.1 - 7.3e-55 185.9 0.0 1.1e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KIY47709.1 - 7.9e-22 77.6 1.2 7.9e-22 77.6 1.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NACHT PF05729.12 KIY47709.1 - 0.0025 17.8 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIY47709.1 - 0.0071 15.6 0.1 0.037 13.2 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.22 KIY47709.1 - 0.075 13.4 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 KIY47709.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 KIY47709.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY47709.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KIY47709.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Mac_assoc PF16628.5 KIY47711.1 - 0.085 13.1 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Unstructured region on maltose acetyltransferase stn_TNFRSF12A PF12191.8 KIY47712.1 - 1.1 9.4 4.3 0.48 10.6 0.3 2.4 2 1 1 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MARVEL PF01284.23 KIY47713.1 - 0.0074 16.3 9.1 0.012 15.6 9.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain MIG-14_Wnt-bd PF06664.12 KIY47713.1 - 0.085 12.1 6.9 0.039 13.2 2.8 2.0 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Homeobox_KN PF05920.11 KIY47714.1 - 5.6e-21 74.2 0.1 7.4e-21 73.8 0.1 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KIY47714.1 - 8e-07 28.8 0.0 8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KIY47714.1 - 0.013 14.9 0.1 0.016 14.6 0.1 1.3 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MGDG_synth PF06925.11 KIY47714.1 - 0.016 15.3 0.0 0.019 15.1 0.0 1.0 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase HTH_29 PF13551.6 KIY47714.1 - 0.046 13.8 0.0 0.063 13.3 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn helix Ras_bdg_2 PF14847.6 KIY47715.1 - 1.7e-09 37.9 0.0 1.7e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Sacchrp_dh_C PF16653.5 KIY47717.1 - 3.9e-75 253.4 0.0 5.5e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 KIY47717.1 - 4.8e-17 62.5 0.0 9.4e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 KIY47717.1 - 3e-16 59.8 0.1 6.1e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KIY47717.1 - 0.0072 15.6 0.0 0.73 9.1 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DNA_pol_phi PF04931.13 KIY47718.1 - 6.6 4.7 6.1 9.8 4.1 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pyr_redox_2 PF07992.14 KIY47719.1 - 2.5e-67 227.2 5.7 3.2e-67 226.8 5.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIY47719.1 - 1.5e-42 144.3 2.5 4.1e-42 142.9 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIY47719.1 - 2.2e-20 73.0 6.1 1.7e-17 63.7 0.7 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY47719.1 - 3.8e-12 46.3 0.1 3.8e-12 46.3 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KIY47719.1 - 5e-12 45.6 1.3 5e-12 45.6 1.3 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIY47719.1 - 3.3e-09 36.4 5.0 1.2e-05 24.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY47719.1 - 7.5e-09 35.7 4.4 5.6e-05 23.3 0.3 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KIY47719.1 - 6.4e-07 28.9 4.5 0.01 15.2 0.2 3.2 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KIY47719.1 - 9.6e-07 28.2 2.3 9.6e-07 28.2 2.3 3.2 3 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KIY47719.1 - 2.6e-06 26.4 15.0 0.00019 20.3 1.5 4.0 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 KIY47719.1 - 6.9e-06 25.4 0.5 0.12 11.5 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KIY47719.1 - 0.00042 19.6 0.2 0.00042 19.6 0.2 2.5 2 0 0 2 2 2 1 Thi4 family THF_DHG_CYH_C PF02882.19 KIY47719.1 - 0.00086 18.7 0.3 0.014 14.7 0.1 2.6 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_3 PF01494.19 KIY47719.1 - 0.00093 18.5 10.2 0.015 14.5 0.7 3.1 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.24 KIY47719.1 - 0.0033 17.0 15.7 0.71 9.4 0.3 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KIY47719.1 - 1.4 8.7 9.1 0.064 13.1 0.8 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KIY47719.1 - 3.9 6.4 7.0 1.6 7.7 0.5 3.0 3 1 0 3 3 3 0 Lycopene cyclase protein Asp PF00026.23 KIY47720.1 - 5.5e-33 114.7 1.2 3.7e-32 112.0 1.2 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY47720.1 - 0.0014 18.9 4.1 0.075 13.3 0.4 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY47720.1 - 0.0079 16.8 1.2 0.63 10.7 0.3 2.8 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIY47720.1 - 0.14 12.7 0.1 0.86 10.2 0.1 2.3 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease zf-RING_2 PF13639.6 KIY47721.1 - 2.1e-12 47.2 5.0 4e-12 46.3 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY47721.1 - 9e-10 38.2 4.0 1.6e-09 37.4 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY47721.1 - 8.7e-09 35.0 1.3 1.8e-08 34.0 1.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KIY47721.1 - 6.4e-08 32.8 5.5 1.3e-07 31.7 5.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KIY47721.1 - 1.2e-07 31.5 3.6 2.2e-07 30.6 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY47721.1 - 4.7e-07 29.7 3.5 8.5e-07 28.8 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIY47721.1 - 3.9e-05 23.6 1.4 7.6e-05 22.7 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KIY47721.1 - 4.8e-05 23.1 3.1 8.9e-05 22.3 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY47721.1 - 0.00066 19.6 1.7 0.0016 18.5 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIY47721.1 - 0.015 14.9 2.6 0.031 13.9 2.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KIY47721.1 - 0.016 15.0 5.4 0.031 14.1 5.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KIY47721.1 - 0.026 14.4 2.8 0.058 13.3 2.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 KIY47721.1 - 0.056 13.3 3.1 0.082 12.8 2.3 1.7 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KIY47721.1 - 0.16 12.3 3.2 0.41 11.0 3.2 1.7 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KIY47721.1 - 0.24 11.6 4.8 0.54 10.4 4.8 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KIY47721.1 - 0.98 9.4 4.8 2.9 7.9 4.8 1.8 1 0 0 1 1 1 0 PHD-finger UBX PF00789.20 KIY47723.1 - 9.2e-13 48.2 0.7 2.1e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 KIY47723.1 - 0.00084 19.2 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 KIY47723.1 - 0.008 16.5 1.8 0.02 15.2 0.5 2.1 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) Borrelia_P83 PF05262.11 KIY47723.1 - 0.063 11.8 16.9 0.07 11.6 16.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-C2H2 PF00096.26 KIY47723.1 - 0.064 13.7 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.6 KIY47723.1 - 0.087 12.8 0.2 0.27 11.2 0.2 1.9 1 0 0 1 1 1 0 zinc-ribbon domain zf-LSD1 PF06943.12 KIY47723.1 - 0.21 11.5 0.5 0.48 10.3 0.5 1.6 1 0 0 1 1 1 0 LSD1 zinc finger YABBY PF04690.13 KIY47723.1 - 6.2 7.4 8.4 39 4.8 8.3 2.0 1 1 0 1 1 1 0 YABBY protein Effector_1 PF04518.12 KIY47723.1 - 10 5.1 9.8 0.29 10.2 2.5 1.8 1 1 1 2 2 2 0 Effector from type III secretion system GPI-anchored PF10342.9 KIY47724.1 - 1.6e-05 25.6 0.7 3.4e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Chol_subst-bind PF09129.11 KIY47725.1 - 0.027 13.5 0.1 0.052 12.5 0.1 1.4 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding F-box-like PF12937.7 KIY47726.1 - 1.8e-06 27.7 0.0 6.3e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 F-box-like Mito_carr PF00153.27 KIY47727.1 - 4e-54 180.5 0.9 4.5e-17 61.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pex19 PF04614.12 KIY47728.1 - 7e-51 173.3 1.3 9.9e-51 172.9 1.3 1.1 1 0 0 1 1 1 1 Pex19 protein family TMEM171 PF15471.6 KIY47728.1 - 1 8.2 4.1 1.6 7.7 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 MFS_1 PF07690.16 KIY47729.1 - 7.7e-37 127.0 19.8 7.7e-37 127.0 19.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY47729.1 - 0.029 13.3 3.8 0.067 12.0 0.1 2.6 2 2 1 3 3 3 0 MFS_1 like family BT1 PF03092.16 KIY47729.1 - 0.035 12.4 1.0 0.043 12.0 0.1 1.6 2 0 0 2 2 2 0 BT1 family SnoaL_4 PF13577.6 KIY47730.1 - 9.1e-10 38.7 0.1 1.2e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 KIY47731.1 - 1.4e-39 136.0 30.1 1.4e-39 136.0 30.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY47731.1 - 4.7e-16 58.7 8.5 4.7e-16 58.7 8.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TAL_FSA PF00923.19 KIY47732.1 - 6.7e-87 291.5 0.0 7.8e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pkinase PF00069.25 KIY47733.1 - 1.1e-25 90.5 0.0 1.7e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47733.1 - 3.7e-09 36.2 0.0 5.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY47733.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY47733.1 - 0.016 15.1 0.9 0.032 14.1 0.3 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family AhpC-TSA PF00578.21 KIY47736.1 - 2e-25 89.1 0.0 2.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY47736.1 - 1.3e-14 54.1 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin LRR_6 PF13516.6 KIY47737.1 - 1e-15 56.4 13.6 0.018 15.1 0.0 8.8 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 KIY47737.1 - 1.2e-05 25.5 16.7 0.091 13.2 2.0 5.6 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) GAT PF03127.14 KIY47737.1 - 0.00024 21.3 0.1 0.00085 19.6 0.1 1.9 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.33 KIY47737.1 - 0.00036 20.7 9.9 17 6.4 0.1 7.1 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 KIY47737.1 - 0.08 12.7 27.5 0.31 10.9 3.4 6.9 5 1 2 7 7 7 0 Leucine rich repeat GST_N_2 PF13409.6 KIY47738.1 - 1.2e-05 25.5 0.1 2.2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY47738.1 - 1.9e-05 25.0 0.1 5.1e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY47738.1 - 0.0035 17.5 0.1 0.026 14.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY47738.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L28 PF00830.19 KIY47738.1 - 1.9 8.8 3.6 1.1 9.5 0.2 2.0 2 0 0 2 2 2 0 Ribosomal L28 family TRAM_LAG1_CLN8 PF03798.16 KIY47739.1 - 0.067 12.9 19.3 0.16 11.7 19.2 1.8 1 1 0 1 1 1 0 TLC domain DUF3337 PF11816.8 KIY47740.1 - 4.7e-43 147.0 0.1 8.3e-43 146.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KIY47740.1 - 8.5e-25 86.5 11.6 1.3e-07 32.2 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY47740.1 - 0.00019 21.7 0.0 0.34 11.3 0.0 3.3 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY47740.1 - 0.012 14.3 2.6 2.3 6.7 0.0 3.2 1 1 1 3 3 3 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KIY47740.1 - 0.092 11.7 0.6 9.6 5.0 0.1 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RNase_P_p30 PF01876.16 KIY47741.1 - 4.6e-37 127.6 0.0 5.6e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 NUDIX PF00293.28 KIY47742.1 - 6.8e-07 29.4 2.4 7.9e-07 29.2 2.0 1.5 1 1 0 1 1 1 1 NUDIX domain FHA PF00498.26 KIY47743.1 - 2.4e-14 53.4 0.0 4.8e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KIY47743.1 - 1.2e-11 44.1 8.4 1.9e-11 43.5 8.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KIY47743.1 - 2.6e-08 34.1 10.2 3.9e-08 33.5 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY47743.1 - 6.2e-05 22.8 9.8 9.5e-05 22.2 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY47743.1 - 8.2e-05 22.4 10.9 0.00013 21.8 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY47743.1 - 0.00039 20.4 1.8 0.00064 19.7 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY47743.1 - 0.00053 20.2 6.9 0.001 19.3 6.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KIY47743.1 - 0.00067 19.6 8.7 0.0011 18.8 8.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY47743.1 - 0.0076 16.3 9.0 0.013 15.5 9.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.29 KIY47743.1 - 0.021 14.7 5.0 0.035 14.0 5.0 1.3 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 KIY47743.1 - 0.032 14.1 6.8 0.053 13.4 6.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) APOBEC4 PF18775.1 KIY47743.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 APOBEC4 Zn_ribbon_17 PF17120.5 KIY47743.1 - 0.59 9.8 5.5 0.97 9.1 5.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SOG2 PF10428.9 KIY47743.1 - 1.2 8.3 5.7 1.5 7.9 5.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Prok-RING_4 PF14447.6 KIY47743.1 - 1.2 9.0 8.2 2.1 8.2 8.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Beach PF02138.18 KIY47744.1 - 5.7e-109 363.8 0.0 9.3e-109 363.1 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 KIY47744.1 - 5.6e-08 33.1 0.0 2e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 KIY47744.1 - 1.2e-07 31.7 0.1 3e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 KIY47744.1 - 0.0005 19.4 1.5 0.0027 17.0 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) WD40 PF00400.32 KIY47744.1 - 0.0053 17.6 0.1 1.7 9.7 0.0 3.4 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.32 KIY47745.1 - 5.6e-08 33.3 0.8 0.071 14.0 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat F-box PF00646.33 KIY47745.1 - 0.00027 20.7 0.1 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY47745.1 - 0.00057 19.7 0.9 0.016 15.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like Elongin_A PF06881.11 KIY47745.1 - 0.0012 19.4 0.3 0.0044 17.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ANAPC4_WD40 PF12894.7 KIY47745.1 - 0.0019 18.4 0.0 1.2 9.4 0.0 3.6 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain ORC5_C PF14630.6 KIY47747.1 - 1.3e-52 179.1 0.0 1.6e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus YycC PF14174.6 KIY47747.1 - 0.13 12.1 0.0 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 YycC-like protein E1-E2_ATPase PF00122.20 KIY47748.1 - 2.1e-23 82.8 0.1 4.6e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KIY47748.1 - 6.4e-14 52.7 0.0 4.6e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIY47748.1 - 0.00015 21.3 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KIY47748.1 - 0.00022 21.3 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIY47748.1 - 0.013 15.3 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glucos_trans_II PF14264.6 KIY47748.1 - 0.36 10.1 9.5 0.19 11.1 0.2 2.9 3 0 0 3 3 3 0 Glucosyl transferase GtrII Glyco_hydro_18 PF00704.28 KIY47749.1 - 6.1e-65 220.0 9.8 6.1e-65 220.0 9.8 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KIY47749.1 - 0.26 12.0 7.1 0.25 12.0 3.4 2.8 2 0 0 2 2 2 0 Carbohydrate binding domain FSA_C PF10479.9 KIY47749.1 - 1.7 6.7 7.0 2.4 6.2 7.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus BRCT_2 PF16589.5 KIY47750.1 - 0.0029 18.0 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Ras PF00071.22 KIY47751.1 - 6.8e-34 116.8 0.3 8e-34 116.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY47751.1 - 1.2e-25 90.0 0.4 2.8e-25 88.9 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY47751.1 - 7.2e-08 32.1 0.1 9.3e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY47751.1 - 6.4e-07 29.0 0.2 8.1e-07 28.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KIY47751.1 - 0.012 14.5 0.2 1.9 7.2 0.0 2.1 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) TniB PF05621.11 KIY47751.1 - 0.021 14.3 0.0 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 KIY47751.1 - 0.023 13.9 1.9 0.12 11.5 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KIY47751.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase rRNA_proc-arch PF13234.6 KIY47752.1 - 1.4e-87 294.1 0.0 2e-87 293.5 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KIY47752.1 - 1.9e-52 177.2 0.3 4.2e-52 176.1 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KIY47752.1 - 6.2e-18 65.2 0.1 5e-17 62.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY47752.1 - 9.4e-07 29.2 0.0 3.7e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY47752.1 - 0.00039 20.5 0.0 0.00095 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KIY47752.1 - 0.0089 15.1 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KIY47752.1 - 0.035 14.4 0.0 0.5 10.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.9 KIY47752.1 - 0.34 10.9 2.3 3.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Com_YlbF PF06133.11 KIY47752.1 - 0.44 11.2 4.4 3.2 8.4 0.2 2.6 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA vATP-synt_E PF01991.18 KIY47753.1 - 3.3e-56 189.9 5.7 3.8e-56 189.7 5.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF883 PF05957.13 KIY47753.1 - 0.32 11.6 3.4 0.46 11.1 1.6 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Sugar_tr PF00083.24 KIY47756.1 - 1.1e-09 37.6 0.0 1.3e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TMEMspv1-c74-12 PF11044.8 KIY47756.1 - 0.15 12.1 0.8 0.26 11.3 0.8 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein F-box-like PF12937.7 KIY47757.1 - 9e-05 22.3 1.7 0.00035 20.4 1.7 2.1 1 0 0 1 1 1 1 F-box-like HTH_31 PF13560.6 KIY47759.1 - 0.015 15.7 0.0 0.026 14.8 0.0 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain RVT_3 PF13456.6 KIY47759.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like PrgI PF12666.7 KIY47759.1 - 0.09 13.5 0.4 0.14 12.9 0.4 1.4 1 0 0 1 1 1 0 PrgI family protein p450 PF00067.22 KIY47760.1 - 1.6e-54 185.4 0.0 2.3e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KIY47762.1 - 8.1e-17 61.5 0.0 8.6e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47762.1 - 0.02 14.2 0.0 0.02 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 KIY47762.1 - 0.1 11.9 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY47762.1 - 0.12 12.2 0.3 0.15 12.0 0.3 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family HET PF06985.11 KIY47764.1 - 4.7e-13 49.7 2.1 5.7e-11 43.0 0.1 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KIY47765.1 - 3.4e-18 66.0 0.0 3.6e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47765.1 - 0.0013 18.1 0.0 0.0014 18.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY47765.1 - 0.02 14.8 0.2 0.025 14.5 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY47765.1 - 0.033 13.8 0.2 0.041 13.5 0.2 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIY47765.1 - 0.089 12.1 0.2 0.1 11.9 0.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tri3 PF07428.11 KIY47769.1 - 6.7e-14 51.6 0.1 3.3e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 15-O-acetyltransferase Tri3 ketoacyl-synt PF00109.26 KIY47770.1 - 5.8e-48 163.7 0.0 1.1e-47 162.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIY47770.1 - 1.8e-37 129.6 0.0 3.3e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KIY47770.1 - 1.4e-32 113.0 0.0 1.1e-28 100.4 0.0 2.4 2 0 0 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.22 KIY47770.1 - 6.4e-31 106.8 0.0 1.3e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KIY47770.1 - 8.7e-24 84.1 0.0 2.4e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein PS-DH PF14765.6 KIY47770.1 - 1.1e-20 74.1 0.0 2.1e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KIY47770.1 - 7.1e-13 49.0 0.0 3e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KIY47770.1 - 1.3e-11 44.4 0.0 3.3e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY47770.1 - 2.1e-07 31.2 0.2 5.7e-07 29.8 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KIY47770.1 - 0.00027 20.4 0.1 0.00059 19.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KIY47770.1 - 0.00067 19.5 0.3 0.0024 17.7 0.3 1.9 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GDP_Man_Dehyd PF16363.5 KIY47770.1 - 0.12 11.8 0.0 3.6 6.9 0.0 2.8 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase HMG_box_2 PF09011.10 KIY47771.1 - 0.017 15.7 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain DUF1178 PF06676.11 KIY47771.1 - 0.063 13.7 0.1 0.095 13.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) LPD38 PF18857.1 KIY47773.1 - 0.022 14.9 0.1 0.063 13.4 0.0 1.7 2 0 0 2 2 2 0 Large polyvalent protein associated domain 38 KDZ PF18758.1 KIY47774.1 - 6.5e-23 81.5 0.0 2.1e-22 79.9 0.0 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY47774.1 - 0.0019 18.3 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY47774.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY47774.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases MAS20 PF02064.15 KIY47775.1 - 0.033 14.3 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor HHH_8 PF14716.6 KIY47775.1 - 0.033 14.5 0.1 0.11 12.9 0.1 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain SIMPL PF04402.14 KIY47775.1 - 0.082 13.4 0.2 0.16 12.4 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF541) Rhabdo_glycop PF00974.18 KIY47775.1 - 0.13 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Abhydrolase_3 PF07859.13 KIY47778.1 - 2.7e-12 47.0 0.0 3.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY47778.1 - 1.2e-09 37.6 0.0 1.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIY47778.1 - 0.14 11.0 0.1 2.9 6.6 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Sugar_tr PF00083.24 KIY47779.1 - 1.2e-100 337.5 19.7 1.4e-100 337.3 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY47779.1 - 5.7e-17 61.7 19.5 5.7e-17 61.7 19.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIY47779.1 - 0.0013 17.1 1.6 0.004 15.5 1.6 1.8 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 KIY47779.1 - 0.047 12.7 12.4 0.013 14.5 2.8 2.6 3 0 0 3 3 3 0 PUCC protein Kdo PF06293.14 KIY47779.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KIY47780.1 - 1.3e-05 25.0 2.0 5e-05 23.1 2.0 2.1 1 0 0 1 1 1 1 F-box-like ABC2_membrane PF01061.24 KIY47781.1 - 2.4e-45 154.5 57.3 1.4e-27 96.5 24.2 3.9 3 1 1 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.27 KIY47781.1 - 3.4e-33 115.1 0.0 1.5e-16 61.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIY47781.1 - 7.9e-25 86.6 12.9 7.6e-21 73.8 0.2 4.0 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY47781.1 - 3.7e-11 43.5 0.0 1.1e-10 42.0 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KIY47781.1 - 4.3e-08 33.2 0.0 7e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KIY47781.1 - 6.1e-07 30.0 0.0 0.00072 20.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KIY47781.1 - 8.6e-07 29.6 0.0 0.0016 19.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KIY47781.1 - 5e-05 23.6 0.0 0.059 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY47781.1 - 0.00016 21.8 0.0 0.078 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY47781.1 - 0.0002 21.1 0.3 0.19 11.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KIY47781.1 - 0.00039 19.7 14.2 0.00039 19.7 14.2 2.6 3 0 0 3 3 2 1 ABC-2 family transporter protein MMR_HSR1 PF01926.23 KIY47781.1 - 0.00039 20.5 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 KIY47781.1 - 0.00064 19.4 1.7 0.032 13.8 0.3 3.0 2 1 1 3 3 3 1 AAA domain cobW PF02492.19 KIY47781.1 - 0.0014 18.2 0.6 0.058 13.0 0.6 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KIY47781.1 - 0.0019 18.5 1.2 2.4 8.4 0.1 3.5 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 KIY47781.1 - 0.0045 17.0 0.3 0.38 10.8 0.4 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KIY47781.1 - 0.0094 16.4 0.0 2.7 8.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KIY47781.1 - 0.011 15.0 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 KIY47781.1 - 0.021 14.8 0.1 0.34 10.8 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KIY47781.1 - 0.021 15.2 0.1 6.9 7.1 0.1 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KIY47781.1 - 0.095 11.7 0.1 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KIY47781.1 - 0.11 13.0 0.4 0.26 11.7 0.1 1.8 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 KIY47781.1 - 0.12 12.8 0.4 5.5 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIY47781.1 - 0.12 12.1 3.8 0.91 9.2 0.3 2.6 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KIY47781.1 - 0.15 11.8 0.7 4.3 7.1 0.1 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 KIY47781.1 - 0.16 11.6 0.1 8.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain dNK PF01712.19 KIY47781.1 - 0.17 11.7 0.0 0.54 10.1 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase Rad51 PF08423.11 KIY47781.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Rad51 Septin PF00735.18 KIY47781.1 - 0.28 10.4 0.0 3.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 KIY47781.1 - 0.35 10.6 0.8 3.4 7.3 0.1 2.4 3 0 0 3 3 3 0 AAA domain p450 PF00067.22 KIY47782.1 - 5e-59 200.3 0.0 6.2e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KIY47784.1 - 5.3e-21 75.2 0.0 5.7e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47784.1 - 2e-12 47.0 0.0 3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY47784.1 - 0.0053 15.6 0.0 0.007 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY47784.1 - 0.029 14.3 0.2 0.071 13.0 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIY47784.1 - 0.19 10.6 0.4 0.27 10.2 0.4 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2034 PF10356.9 KIY47785.1 - 1e-06 28.3 0.8 0.0012 18.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Response_reg PF00072.24 KIY47787.1 - 1.5e-13 50.9 0.3 9.3e-11 41.9 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KIY47787.1 - 7.8e-09 35.4 0.1 2.9e-08 33.6 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PEMT PF04191.13 KIY47788.1 - 6.3e-05 23.3 0.1 0.00014 22.2 0.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KIY47788.1 - 0.0036 17.7 0.6 0.0075 16.7 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KIY47788.1 - 0.016 14.0 1.8 0.11 11.2 1.8 2.0 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KIY47789.1 - 7.1e-05 23.2 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KIY47789.1 - 0.00088 19.7 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KIY47789.1 - 0.0077 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KIY47789.1 - 0.0091 14.8 0.6 0.04 12.7 0.6 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NAD_binding_4 PF07993.12 KIY47791.1 - 7.1e-24 84.4 0.0 1.2e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIY47791.1 - 7.7e-22 77.5 0.0 3.1e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KIY47791.1 - 3.7e-09 36.4 0.0 6.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY47791.1 - 2.1e-06 28.0 0.0 4.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 KIY47791.1 - 0.23 10.5 0.0 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KIY47793.1 - 1.8e-42 145.0 0.8 2.2e-42 144.8 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY47793.1 - 5.2e-32 111.3 0.6 6.4e-32 111.0 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY47793.1 - 2.6e-07 30.7 1.2 4e-07 30.1 1.2 1.2 1 0 0 1 1 1 1 KR domain DUF3012 PF11216.8 KIY47793.1 - 0.13 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Zn_clus PF00172.18 KIY47794.1 - 4.7e-07 29.8 5.4 8.8e-07 29.0 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY47795.1 - 8.4e-06 25.8 14.5 1.3e-05 25.2 14.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CdvA PF18822.1 KIY47795.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain MARVEL PF01284.23 KIY47797.1 - 0.024 14.7 11.6 0.037 14.0 11.6 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF1230 PF06799.11 KIY47797.1 - 4 7.6 6.3 9.3 6.4 6.3 1.7 1 1 0 1 1 1 0 Conserved in the green lineage and diatoms 27 Thaumatin PF00314.17 KIY47798.1 - 2.1e-62 210.6 11.2 2.5e-62 210.3 11.2 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIY47798.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Beta-1,3-glucanase Nodulin_late PF07127.11 KIY47798.1 - 1.7 9.0 0.0 1.7 9.0 0.0 2.9 4 0 0 4 4 4 0 Late nodulin protein Sel1 PF08238.12 KIY47800.1 - 1.3e-20 73.3 10.4 1.9e-06 28.3 0.6 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 KIY47800.1 - 0.15 12.8 0.7 84 4.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY47800.1 - 0.76 10.0 6.2 1.2 9.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 KIY47801.1 - 7.4e-07 29.0 0.8 2.1e-06 27.5 0.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY47801.1 - 0.013 15.3 0.8 2.1 8.3 0.2 2.8 2 0 0 2 2 2 0 F-box domain DUF4127 PF13552.6 KIY47801.1 - 0.25 9.9 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) AhpC-TSA PF00578.21 KIY47802.1 - 5.1e-34 116.9 0.0 8.4e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY47802.1 - 4e-15 55.8 0.0 5.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KIY47802.1 - 1.3e-11 44.1 0.0 2.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KIY47802.1 - 0.076 12.9 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 SCO1/SenC Peptidase_S10 PF00450.22 KIY47803.1 - 1.6e-102 344.1 0.0 1.9e-102 343.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase F-box-like PF12937.7 KIY47805.1 - 1.8e-05 24.5 0.0 5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY47805.1 - 3.1e-05 23.7 0.0 0.00011 22.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain Cu-oxidase PF00394.22 KIY47806.1 - 2.8e-45 154.3 1.3 9.1e-41 139.6 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY47806.1 - 2.9e-36 124.2 2.8 9.6e-34 116.1 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY47806.1 - 1.2e-35 122.1 2.8 3.8e-33 114.0 0.1 2.8 2 0 0 2 2 2 2 Multicopper oxidase Abhydrolase_3 PF07859.13 KIY47808.1 - 4.8e-18 65.8 0.0 7.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY47808.1 - 2.1e-15 56.5 0.0 4.3e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase MFS_1 PF07690.16 KIY47810.1 - 1.2e-19 70.4 23.2 1.2e-19 70.4 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu-oxidase PF00394.22 KIY47812.1 - 9.5e-44 149.3 1.8 3.9e-41 140.8 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY47812.1 - 1e-36 125.7 3.7 1.7e-33 115.2 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY47812.1 - 5.1e-36 123.3 2.6 7.3e-33 113.1 0.2 2.8 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KIY47813.1 - 9.7e-46 155.8 0.8 8.1e-41 139.8 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY47813.1 - 3.1e-37 127.4 2.2 3.7e-34 117.4 0.0 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY47813.1 - 1.2e-34 118.9 0.7 9.2e-33 112.8 0.1 2.7 2 0 0 2 2 2 1 Multicopper oxidase SIR2 PF02146.17 KIY47814.1 - 3.1e-34 118.4 0.0 1.6e-33 116.1 0.0 2.1 1 1 0 1 1 1 1 Sir2 family WD40 PF00400.32 KIY47815.1 - 2.2e-22 78.9 13.4 3.6e-05 24.4 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY47815.1 - 3.3e-08 33.7 3.6 0.051 13.9 0.0 4.8 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY47815.1 - 1e-05 24.7 0.0 1.9 7.3 0.0 3.6 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PLDc PF00614.22 KIY47816.1 - 9.3e-18 63.6 3.1 1.3e-09 37.8 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KIY47816.1 - 1.9e-16 60.1 0.1 1e-06 28.7 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain VWA_2 PF13519.6 KIY47817.1 - 1e-23 84.0 0.2 1e-23 84.0 0.2 2.3 4 0 0 4 4 4 1 von Willebrand factor type A domain UIM PF02809.20 KIY47817.1 - 3.3e-11 42.3 20.5 0.00028 20.6 0.4 3.9 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 KIY47817.1 - 5e-09 36.3 0.2 8.9e-09 35.4 0.2 1.4 1 0 0 1 1 1 1 Ssl1-like FMN_red PF03358.15 KIY47817.1 - 0.028 14.2 0.0 0.081 12.7 0.0 1.8 2 0 0 2 2 2 0 NADPH-dependent FMN reductase PDH PF02153.17 KIY47817.1 - 0.035 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase ANF_receptor PF01094.28 KIY47817.1 - 0.046 12.8 0.1 1.8 7.6 0.1 2.2 1 1 1 2 2 2 0 Receptor family ligand binding region Glyco_tran_WecB PF03808.13 KIY47817.1 - 0.12 12.3 0.2 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Tri3 PF07428.11 KIY47818.1 - 0.038 12.9 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 DUF2236 PF09995.9 KIY47820.1 - 0.0012 19.1 1.4 0.0044 17.3 1.2 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF4219 PF13961.6 KIY47821.1 - 0.012 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) DNA_processg_A PF02481.15 KIY47821.1 - 0.053 12.8 0.6 0.069 12.4 0.6 1.1 1 0 0 1 1 1 0 DNA recombination-mediator protein A APH PF01636.23 KIY47822.1 - 6.8e-12 45.8 0.0 2.9e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIY47822.1 - 2.6e-08 33.2 0.0 0.0011 17.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.25 KIY47824.1 - 1.9e-06 27.4 0.0 0.00022 20.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47824.1 - 0.00092 18.6 0.0 0.45 9.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase BRCA-2_helical PF09169.10 KIY47828.1 - 2.3e-05 24.1 0.0 5.9e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 BRCA2, helical Aldo_ket_red PF00248.21 KIY47830.1 - 1.6e-15 57.1 0.0 1.6e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SIMPL PF04402.14 KIY47831.1 - 0.033 14.6 0.2 0.034 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) KDZ PF18758.1 KIY47832.1 - 1.8e-62 210.9 0.3 2.3e-62 210.5 0.3 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase HupE_UreJ PF04955.12 KIY47832.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 HupE / UreJ protein bMG1 PF17970.1 KIY47832.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG1 domain Ammonium_transp PF00909.21 KIY47833.1 - 2.8e-13 49.3 4.7 3.1e-13 49.2 4.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PA26 PF04636.13 KIY47836.1 - 2.9 6.7 6.9 4.3 6.2 6.9 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Sec23_trunk PF04811.15 KIY47838.1 - 3.5e-47 161.0 0.0 5.2e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KIY47838.1 - 4e-17 62.7 0.1 7.9e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KIY47838.1 - 3.4e-14 52.6 6.5 9.6e-14 51.2 6.5 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 KIY47838.1 - 3.8e-14 52.3 0.0 6.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KIY47838.1 - 0.00016 21.5 0.0 0.0005 19.9 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat MRNIP PF15749.5 KIY47838.1 - 0.54 11.0 3.5 1.3 9.8 3.5 1.5 1 0 0 1 1 1 0 MRN-interacting protein Glyco_hydro_43 PF04616.14 KIY47839.1 - 2.6e-38 132.0 0.5 3.2e-38 131.7 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KIY47839.1 - 0.0076 15.8 0.0 0.52 9.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain SNF2_N PF00176.23 KIY47840.1 - 4.5e-46 157.2 0.0 1.2e-45 155.8 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KIY47840.1 - 4.7e-06 26.4 12.1 9.4e-06 25.4 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY47840.1 - 6.8e-06 25.9 11.9 1.3e-05 25.0 11.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY47840.1 - 8.2e-06 25.6 7.3 1.4e-05 24.8 7.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIY47840.1 - 0.00016 22.0 15.2 0.00031 21.0 15.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIY47840.1 - 0.0016 18.3 14.6 0.003 17.5 14.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIY47840.1 - 0.0044 16.8 16.5 0.0083 15.9 16.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KIY47840.1 - 0.019 15.3 1.9 0.023 15.0 0.2 2.1 2 0 0 2 2 2 0 Helicase conserved C-terminal domain zf-rbx1 PF12678.7 KIY47840.1 - 0.024 14.9 9.7 0.054 13.8 9.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 KIY47840.1 - 0.22 11.4 2.9 0.81 9.6 0.0 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.6 KIY47840.1 - 0.89 9.6 9.9 2 8.5 9.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIY47840.1 - 2.3 7.9 9.3 6 6.6 9.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KIY47840.1 - 6.5 6.9 9.0 27 4.9 9.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KIY47840.1 - 8.4 6.6 10.5 17 5.7 10.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3189 PF11385.8 KIY47841.1 - 0.039 13.8 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) Aminotran_1_2 PF00155.21 KIY47842.1 - 2.5e-26 92.7 0.0 1.5e-25 90.2 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II HCNGP PF07818.13 KIY47843.1 - 3e-31 107.9 0.0 4.5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein T-box PF00907.22 KIY47843.1 - 0.017 15.4 0.1 0.022 15.0 0.1 1.1 1 0 0 1 1 1 0 T-box PutA_N PF18083.1 KIY47843.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Proline utilization A N-terminal domain DnaJ PF00226.31 KIY47844.1 - 4.2e-21 74.8 0.2 1.4e-20 73.2 0.2 2.0 2 0 0 2 2 2 1 DnaJ domain Exonuc_VII_L PF02601.15 KIY47844.1 - 0.43 10.1 6.2 0.61 9.6 6.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KIY47844.1 - 3.5 6.9 9.0 5.9 6.2 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MR_MLE_C PF13378.6 KIY47845.1 - 5.4e-46 156.9 0.1 4.1e-45 154.0 0.1 2.0 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIY47845.1 - 1.2e-06 28.8 0.0 3.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_C25_C PF03785.14 KIY47845.1 - 0.048 13.5 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain OTT_1508_deam PF14441.6 KIY47846.1 - 0.052 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase Phage_integrase PF00589.22 KIY47847.1 - 0.00011 22.0 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family OTT_1508_deam PF14441.6 KIY47849.1 - 0.053 13.5 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase RNA_pol_L_2 PF13656.6 KIY47851.1 - 6.5e-28 96.3 0.0 8.1e-28 96.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KIY47851.1 - 6.9e-08 31.8 0.0 9.3e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_S11 PF00411.19 KIY47853.1 - 1.5e-46 157.3 1.7 1.9e-46 157.0 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 KIY47853.1 - 0.057 12.7 0.1 0.075 12.3 0.1 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme CBM_25 PF03423.13 KIY47853.1 - 0.088 13.1 0.1 0.17 12.1 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) TPR_2 PF07719.17 KIY47854.1 - 1.7e-18 65.1 11.7 0.0094 16.0 0.0 11.5 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY47854.1 - 5.7e-12 45.4 9.1 3.1 8.9 0.2 10.1 6 3 4 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY47854.1 - 1e-11 44.9 22.6 4.3e-05 23.7 0.0 9.2 8 2 3 11 11 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY47854.1 - 1.9e-11 44.3 19.4 0.0065 16.9 0.5 8.4 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY47854.1 - 6.5e-11 41.6 10.9 1 9.3 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY47854.1 - 2.6e-09 37.6 5.4 0.34 11.6 0.0 6.0 8 0 0 8 8 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY47854.1 - 3.4e-09 36.3 8.9 0.0004 20.0 0.0 6.4 7 0 0 7 7 7 2 TPR repeat TPR_8 PF13181.6 KIY47854.1 - 3.8e-09 36.0 21.3 0.11 12.8 0.0 10.7 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY47854.1 - 4.3e-08 32.6 8.8 2.6 8.3 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY47854.1 - 6.8e-08 32.4 6.6 0.011 16.1 0.1 5.5 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY47854.1 - 2.6e-06 27.5 7.7 0.71 10.1 0.0 6.4 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KIY47854.1 - 2.9e-05 24.4 8.0 28 5.6 0.2 8.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIY47854.1 - 5.7e-05 23.6 1.2 0.09 13.2 0.1 3.7 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_9 PF13371.6 KIY47854.1 - 9.1e-05 22.5 4.6 0.054 13.7 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KIY47854.1 - 0.00097 19.4 5.1 0.13 12.6 0.5 4.3 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KIY47854.1 - 0.22 10.9 11.5 0.16 11.3 0.1 4.8 5 1 0 5 5 5 0 MalT-like TPR region ANAPC5 PF12862.7 KIY47854.1 - 0.26 11.4 7.9 25 5.0 0.1 5.0 6 0 0 6 6 5 0 Anaphase-promoting complex subunit 5 SNAP PF14938.6 KIY47854.1 - 0.68 9.3 11.4 0.59 9.5 1.5 4.2 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KIY47854.1 - 2.7 8.0 20.7 15 5.6 0.0 7.8 10 0 0 10 10 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KIY47854.1 - 3.7 7.5 9.0 69 3.4 0.4 4.9 4 1 1 5 5 5 0 Mad3/BUB1 homology region 1 CHASE3 PF05227.13 KIY47854.1 - 5.3 7.0 11.3 3.1 7.7 0.0 3.8 4 0 0 4 4 4 0 CHASE3 domain MAM33 PF02330.16 KIY47856.1 - 1.4e-64 217.9 5.5 1.7e-64 217.7 5.5 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein adh_short PF00106.25 KIY47857.1 - 1.6e-26 93.0 0.0 9e-22 77.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY47857.1 - 5.9e-16 58.7 0.0 5.1e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY47857.1 - 4.9e-07 29.8 0.0 8.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NitrOD5 PF11537.8 KIY47857.1 - 0.0007 19.7 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Nitrosopumilus output domain 5 Sacchrp_dh_NADP PF03435.18 KIY47857.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIY47857.1 - 0.046 13.2 0.1 0.11 11.9 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Oxidored_FMN PF00724.20 KIY47859.1 - 3.9e-29 102.0 0.0 5e-24 85.2 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family BCDHK_Adom3 PF10436.9 KIY47860.1 - 2.6e-65 219.2 0.0 3.3e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIY47860.1 - 2.2e-13 50.7 0.0 8.4e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIY47860.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3719 PF12516.8 KIY47860.1 - 0.0094 15.6 0.5 0.031 14.0 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3719) Amidohydro_2 PF04909.14 KIY47861.1 - 5.5e-20 72.3 0.1 8.2e-20 71.8 0.1 1.3 1 1 0 1 1 1 1 Amidohydrolase Pkinase PF00069.25 KIY47862.1 - 2.6e-41 141.7 0.0 2.4e-28 99.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47862.1 - 6e-25 88.0 0.0 8.3e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY47862.1 - 0.00062 18.7 0.0 0.00087 18.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY47862.1 - 0.027 14.4 0.3 0.063 13.2 0.3 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Herpes_ORF11 PF04797.13 KIY47862.1 - 0.029 13.2 0.1 0.042 12.6 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein MutS_V PF00488.21 KIY47863.1 - 3.4e-59 200.1 0.2 6e-59 199.2 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIY47863.1 - 1.1e-35 123.7 0.1 3.5e-35 122.0 0.1 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KIY47863.1 - 9.9e-33 112.8 0.1 2.6e-32 111.4 0.1 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KIY47863.1 - 1e-14 55.0 0.1 4.4e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 MutS domain II Mad3_BUB1_I PF08311.12 KIY47864.1 - 6.9e-36 123.0 0.2 8.6e-36 122.6 0.2 1.1 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 SET PF00856.28 KIY47865.1 - 3.9e-14 53.4 0.0 2e-13 51.1 0.0 2.1 1 1 0 1 1 1 1 SET domain Sel1 PF08238.12 KIY47865.1 - 0.79 10.5 3.2 0.66 10.8 0.9 2.0 2 0 0 2 2 2 0 Sel1 repeat DUF667 PF05018.13 KIY47867.1 - 2.3e-23 82.9 0.0 1.4e-14 54.3 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF667) TPR_2 PF07719.17 KIY47868.1 - 4.2e-05 23.3 2.2 0.43 10.8 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY47868.1 - 6.3e-05 23.2 0.6 0.00022 21.5 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY47868.1 - 0.013 15.3 0.4 9.5 6.2 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 KIY47868.1 - 0.016 15.3 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain P53_TAD PF08563.11 KIY47868.1 - 0.042 13.3 0.1 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 P53 transactivation motif DUF3915 PF13054.6 KIY47868.1 - 0.62 10.1 4.5 0.5 10.4 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) RRM_1 PF00076.22 KIY47869.1 - 1.2e-20 73.1 0.0 7.4e-13 48.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY47869.1 - 0.00013 21.5 0.0 0.065 12.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY47869.1 - 0.017 15.0 0.0 3.4 7.6 0.0 2.6 3 0 0 3 3 3 0 Occluded RNA-recognition motif AdoHcyase PF05221.17 KIY47869.1 - 0.04 13.1 0.3 0.23 10.6 0.1 2.0 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase Limkain-b1 PF11608.8 KIY47869.1 - 0.068 13.3 0.6 20 5.3 0.0 3.0 3 1 0 3 3 3 0 Limkain b1 Amino_oxidase PF01593.24 KIY47870.1 - 2e-55 188.9 0.1 3e-55 188.3 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY47870.1 - 3.9e-09 36.6 0.0 1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SIS PF01380.22 KIY47871.1 - 2.9e-62 208.3 0.2 4.2e-31 107.5 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KIY47871.1 - 5.5e-16 59.0 0.0 1.3e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIY47871.1 - 4.5e-12 45.9 0.0 1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KIY47871.1 - 0.0013 17.7 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Aldo_ket_red PF00248.21 KIY47872.1 - 4.6e-34 117.9 0.0 6.6e-30 104.3 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family G_glu_transpept PF01019.21 KIY47873.1 - 6.2e-97 325.5 2.7 3.6e-81 273.5 0.0 3.2 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase Robl_LC7 PF03259.17 KIY47873.1 - 0.007 16.1 1.4 0.056 13.2 0.0 2.7 3 1 0 3 3 3 1 Roadblock/LC7 domain Rad51 PF08423.11 KIY47875.1 - 0.091 12.0 0.0 3.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Rad51 RNA_pol_A_CTD PF03118.15 KIY47875.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Abhydrolase_1 PF00561.20 KIY47876.1 - 5e-16 59.1 0.0 2.5e-15 56.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY47876.1 - 2.5e-12 46.6 0.0 8.8e-12 44.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY47876.1 - 1.5e-11 45.3 0.0 1.9e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KIY47876.1 - 3.3e-05 23.6 0.0 5.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 KIY47876.1 - 9.2e-05 22.1 0.0 0.00054 19.6 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KIY47876.1 - 0.0076 16.1 0.3 0.33 10.8 0.4 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KIY47876.1 - 0.0084 16.2 0.1 0.019 15.1 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Ndr PF03096.14 KIY47876.1 - 0.019 13.6 0.0 0.047 12.4 0.0 1.5 2 0 0 2 2 2 0 Ndr family Abhydrolase_2 PF02230.16 KIY47876.1 - 0.12 12.1 0.1 2.7 7.7 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KIY47876.1 - 0.17 11.8 0.0 8.1 6.3 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PIG-P PF08510.12 KIY47877.1 - 5.9e-32 110.1 4.6 7e-32 109.9 4.6 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KIY47877.1 - 0.38 11.1 11.9 1.1 9.6 11.9 1.8 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PDEase_I PF00233.19 KIY47878.1 - 2e-51 175.0 0.1 3.2e-51 174.3 0.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase LVIVD PF08309.11 KIY47878.1 - 5.3 6.4 4.7 6.3 6.2 0.1 2.6 3 0 0 3 3 3 0 LVIVD repeat adh_short PF00106.25 KIY47879.1 - 2e-26 92.7 1.5 4.2e-21 75.3 1.1 2.6 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY47879.1 - 4e-14 52.8 0.7 6.9e-13 48.7 0.5 2.6 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY47879.1 - 4e-09 36.6 0.3 6.5e-09 35.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY47879.1 - 6.1e-07 29.2 0.1 9.2e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY47879.1 - 0.0015 18.0 0.1 0.004 16.6 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase LacAB_rpiB PF02502.18 KIY47879.1 - 0.026 14.5 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Ribose/Galactose Isomerase Ribosomal_L14e PF01929.17 KIY47880.1 - 4e-26 91.3 2.0 5.8e-26 90.8 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KIY47880.1 - 9.1e-06 25.4 1.1 0.00012 21.8 0.1 2.7 2 1 1 3 3 3 2 KOW motif Peptidase_C13 PF01650.18 KIY47881.1 - 1.2e-42 146.2 0.1 1.6e-42 145.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 KIY47881.1 - 0.088 13.1 0.2 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 Mid domain of argonaute EthD PF07110.11 KIY47882.1 - 5.6e-06 27.4 0.3 0.059 14.5 0.2 2.4 2 0 0 2 2 2 2 EthD domain WD40 PF00400.32 KIY47883.1 - 4.6e-59 195.0 17.9 1.9e-09 38.0 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY47883.1 - 1.8e-23 82.6 0.2 6.6e-05 23.1 0.0 6.7 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY47883.1 - 1.7e-11 44.0 0.1 0.015 14.6 0.0 5.7 4 2 2 6 6 6 3 WD40-like domain Ge1_WD40 PF16529.5 KIY47883.1 - 2e-10 40.1 1.6 0.74 8.7 0.0 6.5 2 2 5 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIY47883.1 - 2.2e-06 27.7 0.0 0.059 13.2 0.0 3.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIY47883.1 - 2.7e-05 23.9 2.5 30 4.7 0.0 6.3 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIY47883.1 - 3.8e-05 22.5 0.7 0.062 11.9 0.0 3.3 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIY47883.1 - 0.00012 21.5 0.4 4.3 6.6 0.0 4.0 3 2 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KIY47883.1 - 0.00049 18.7 0.8 0.01 14.4 0.1 3.0 2 1 2 4 4 4 1 Cytochrome D1 heme domain nos_propeller PF18764.1 KIY47883.1 - 0.015 15.2 0.0 3.9 7.5 0.0 3.6 2 1 1 3 3 3 0 Nitrous oxide reductase propeller repeat Reg_prop PF07494.11 KIY47883.1 - 0.028 14.6 0.1 27 5.4 0.0 4.9 5 0 0 5 5 4 0 Two component regulator propeller Peptidase_S9_N PF02897.15 KIY47883.1 - 0.079 11.7 0.1 12 4.5 0.0 3.1 2 1 2 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain RAB3GAP2_N PF14655.6 KIY47883.1 - 0.12 11.6 0.1 10 5.3 0.0 3.2 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Secretin_N_2 PF07655.13 KIY47883.1 - 0.16 12.6 4.3 3.8 8.1 3.3 2.7 2 1 0 2 2 2 0 Secretin N-terminal domain Proteasome_A_N PF10584.9 KIY47883.1 - 0.18 11.5 5.9 18 5.1 0.0 4.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature TraL PF07178.11 KIY47884.1 - 0.18 12.3 0.3 0.18 12.3 0.3 2.3 2 1 1 3 3 3 0 TraL protein PAS_9 PF13426.7 KIY47885.1 - 1.4e-23 83.1 0.0 6.9e-16 58.4 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KIY47885.1 - 3.3e-14 52.9 0.0 3e-11 43.4 0.0 3.8 3 1 0 3 3 3 1 PAS fold PAS PF00989.25 KIY47885.1 - 1.6e-08 34.5 0.0 7.6e-05 22.7 0.0 3.1 3 2 0 3 3 3 2 PAS fold PAS_4 PF08448.10 KIY47885.1 - 5.4e-08 33.1 0.0 0.00081 19.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KIY47885.1 - 0.00028 21.0 0.0 0.00069 19.7 0.0 1.6 1 1 0 1 1 1 1 PAS domain Pkinase PF00069.25 KIY47886.1 - 2.7e-47 161.3 0.0 3.9e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY47886.1 - 2.1e-28 99.3 0.0 2.4e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY47886.1 - 7.5e-05 22.2 0.0 9.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY47886.1 - 0.002 17.5 0.1 0.0029 17.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KIY47886.1 - 0.088 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 KIY47886.1 - 0.14 10.9 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APG6_N PF17675.1 KIY47887.1 - 0.0004 20.9 3.1 0.0004 20.9 3.1 6.6 4 2 3 7 7 7 1 Apg6 coiled-coil region Fez1 PF06818.15 KIY47887.1 - 0.0064 17.0 9.2 0.0064 17.0 9.2 5.6 2 2 4 6 6 5 2 Fez1 Mrr_N PF14338.6 KIY47887.1 - 0.018 15.2 5.1 0.36 11.0 0.4 3.5 2 0 0 2 2 2 0 Mrr N-terminal domain Ribosomal_L3 PF00297.22 KIY47887.1 - 0.02 13.9 0.3 0.053 12.5 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L3 betaPIX_CC PF16523.5 KIY47887.1 - 0.036 13.9 0.2 0.036 13.9 0.2 2.9 3 0 0 3 3 3 0 betaPIX coiled coil AAA_13 PF13166.6 KIY47887.1 - 0.099 11.3 42.3 0.2 10.2 9.0 3.1 1 1 2 3 3 3 0 AAA domain LPP PF04728.13 KIY47887.1 - 0.13 12.6 0.2 0.13 12.6 0.2 7.2 5 3 2 7 7 7 0 Lipoprotein leucine-zipper Filament PF00038.21 KIY47887.1 - 0.22 11.0 52.3 0.44 10.1 29.8 4.0 1 1 2 3 3 3 0 Intermediate filament protein FlaC_arch PF05377.11 KIY47887.1 - 0.87 10.0 17.0 27 5.2 0.1 6.4 7 0 0 7 7 6 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KIY47887.1 - 0.95 8.3 59.4 0.059 12.3 16.5 4.9 1 1 4 5 5 5 0 Spc7 kinetochore protein SHE3 PF17078.5 KIY47887.1 - 1.2 8.9 27.0 0.44 10.2 3.5 4.6 1 1 3 5 5 5 0 SWI5-dependent HO expression protein 3 MAD PF05557.13 KIY47887.1 - 2.4 6.4 50.1 0.061 11.7 23.1 3.6 1 1 2 3 3 3 0 Mitotic checkpoint protein Atg14 PF10186.9 KIY47887.1 - 2.8 7.0 52.8 0.51 9.4 9.1 4.5 1 1 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KIY47887.1 - 4.7 7.0 41.5 0.02 14.7 1.8 5.0 1 1 2 4 4 4 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KIY47887.1 - 7.1 6.8 87.6 0.12 12.6 11.2 6.5 3 1 4 7 7 7 0 Autophagy protein 16 (ATG16) Rad52_Rad22 PF04098.15 KIY47888.1 - 1.9e-56 190.2 0.0 2.4e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PIG-L PF02585.17 KIY47889.1 - 6.2e-23 81.9 0.2 8.2e-23 81.5 0.2 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_hydro_53 PF07745.13 KIY47890.1 - 3.7e-83 279.3 0.0 4.2e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Myotub-related PF06602.14 KIY47890.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain Cellulase PF00150.18 KIY47890.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) PBP PF01161.20 KIY47891.1 - 2.5e-17 63.4 0.0 3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Histone_H2A_C PF16211.5 KIY47892.1 - 2.2e-18 65.7 1.3 4.2e-18 64.8 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KIY47892.1 - 4.2e-18 66.0 0.0 5.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIY47892.1 - 1.3e-06 28.6 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Glyco_transf_20 PF00982.21 KIY47893.1 - 1.4e-144 482.3 0.0 2e-144 481.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KIY47893.1 - 1.2e-68 230.7 0.0 3.8e-68 229.1 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 KIY47893.1 - 0.023 14.4 0.3 0.046 13.4 0.3 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain TSP_NTD PF17804.1 KIY47893.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Phage_TAC_1 PF06222.11 KIY47893.1 - 0.12 12.1 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone Zn_clus PF00172.18 KIY47894.1 - 0.018 15.2 14.9 0.026 14.6 14.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sterol_MT_C PF08498.10 KIY47895.1 - 1.6e-29 102.0 0.6 2.5e-29 101.4 0.6 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 KIY47895.1 - 6.5e-18 65.0 0.0 9.8e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY47895.1 - 9.4e-17 61.5 0.0 1.6e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY47895.1 - 4.7e-16 59.3 0.0 8.1e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIY47895.1 - 7.4e-12 45.1 0.0 9.8e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KIY47895.1 - 9.4e-10 39.1 0.0 2.3e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY47895.1 - 2.1e-09 37.4 0.0 3.2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY47895.1 - 3.7e-07 29.7 0.0 6.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KIY47895.1 - 1.8e-05 24.4 0.1 2.8e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KIY47895.1 - 2.6e-05 24.1 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 KIY47895.1 - 0.00012 21.3 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.14 KIY47895.1 - 0.0019 17.8 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KIY47895.1 - 0.0021 17.7 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 KIY47895.1 - 0.0084 17.1 0.0 0.031 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIY47895.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain UPF0020 PF01170.18 KIY47895.1 - 0.043 13.5 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 KIY47895.1 - 0.081 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MFS_1 PF07690.16 KIY47896.1 - 4.8e-38 131.0 43.7 6.3e-37 127.3 43.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY47896.1 - 8.1e-13 47.7 19.2 1.3e-12 47.0 19.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIY47896.1 - 4.4e-07 29.1 12.3 4.4e-07 29.1 12.3 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter PhoLip_ATPase_C PF16212.5 KIY47896.1 - 0.23 11.2 3.4 10 5.8 0.1 2.4 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal Aldedh PF00171.22 KIY47898.1 - 1.6e-83 280.8 0.0 1.7e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LRR_6 PF13516.6 KIY47899.1 - 1.4e-07 31.0 3.3 0.42 10.8 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich repeat F-box-like PF12937.7 KIY47899.1 - 0.066 13.1 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 F-box-like Trypsin_2 PF13365.6 KIY47900.1 - 0.019 15.8 0.0 3.5 8.5 0.0 2.5 2 1 0 2 2 2 0 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 KIY47900.1 - 0.027 13.6 1.0 0.38 9.9 0.1 2.1 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DUF397 PF04149.12 KIY47900.1 - 0.17 12.0 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF397) DUF4246 PF14033.6 KIY47901.1 - 8.8e-125 417.3 0.0 1.1e-124 417.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) HLH PF00010.26 KIY47902.1 - 5e-09 36.0 0.4 2.7e-08 33.7 0.0 2.5 4 0 0 4 4 4 1 Helix-loop-helix DNA-binding domain PKcGMP_CC PF16808.5 KIY47902.1 - 0.039 13.8 3.5 0.08 12.8 3.5 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MFS_1 PF07690.16 KIY47903.1 - 2.7e-14 52.9 38.9 2.7e-12 46.3 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PEN-2 PF10251.9 KIY47903.1 - 0.12 12.8 1.0 2.2 8.8 0.3 2.8 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF4239 PF14023.6 KIY47903.1 - 0.78 9.4 2.4 1.4 8.6 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) RRM_1 PF00076.22 KIY47904.1 - 3.7e-10 39.5 0.1 6.9e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KIY47904.1 - 0.014 15.9 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SKA1 PF07160.12 KIY47905.1 - 3.8e-05 23.7 0.8 6.5e-05 22.9 0.8 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 ADIP PF11559.8 KIY47905.1 - 0.00068 19.7 0.6 0.0014 18.7 0.6 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KIY47905.1 - 0.00097 18.3 2.7 0.0016 17.6 2.7 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KIY47905.1 - 0.0021 18.3 2.1 0.0021 18.3 2.1 1.6 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KIY47905.1 - 0.0058 15.6 0.3 0.0098 14.8 0.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein SlyX PF04102.12 KIY47905.1 - 0.011 16.4 0.5 0.53 10.9 0.3 3.1 3 0 0 3 3 3 0 SlyX Fez1 PF06818.15 KIY47905.1 - 0.015 15.7 1.2 0.031 14.7 1.2 1.6 1 0 0 1 1 1 0 Fez1 Filament PF00038.21 KIY47905.1 - 0.016 14.8 0.3 0.026 14.1 0.3 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF2630 PF10944.8 KIY47905.1 - 0.017 15.6 0.5 0.11 13.0 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) APG6_N PF17675.1 KIY47905.1 - 0.024 15.1 1.5 0.042 14.4 1.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region TSNAXIP1_N PF15739.5 KIY47905.1 - 0.041 14.3 0.6 0.12 12.7 0.6 1.8 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus BMFP PF04380.13 KIY47905.1 - 0.046 14.2 0.6 0.63 10.6 0.1 2.5 2 0 0 2 2 2 0 Membrane fusogenic activity CENP-F_leu_zip PF10473.9 KIY47905.1 - 0.052 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4763 PF15960.5 KIY47905.1 - 0.061 12.6 0.5 0.12 11.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Cep57_CLD PF14073.6 KIY47905.1 - 0.062 13.3 2.1 0.11 12.5 2.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Ax_dynein_light PF10211.9 KIY47905.1 - 0.097 12.6 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain Mod_r PF07200.13 KIY47905.1 - 0.1 12.7 0.7 0.22 11.6 0.7 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein JIP_LZII PF16471.5 KIY47905.1 - 0.11 12.7 0.9 0.27 11.5 0.2 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CENP-Q PF13094.6 KIY47905.1 - 0.26 11.5 5.6 1.3 9.2 4.9 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Phytase-like PF13449.6 KIY47906.1 - 9.4e-27 94.7 0.0 1.6e-26 93.9 0.0 1.5 1 1 0 1 1 1 1 Esterase-like activity of phytase Mg_trans_NIPA PF05653.14 KIY47907.1 - 1.2e-80 270.8 32.0 1.5e-80 270.4 32.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KIY47907.1 - 9.5e-07 29.1 8.0 9.5e-07 29.1 8.0 3.5 2 2 1 3 3 3 2 EamA-like transporter family Vif PF00559.17 KIY47908.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Retroviral Vif (Viral infectivity) protein Ribosomal_L27A PF00828.19 KIY47910.1 - 3e-22 79.7 0.0 4.4e-22 79.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sec23_trunk PF04811.15 KIY47912.1 - 2.6e-68 230.2 0.0 6.1e-68 229.0 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KIY47912.1 - 1.6e-21 76.0 0.0 5e-21 74.4 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KIY47912.1 - 2.6e-17 63.3 0.1 7.1e-17 61.9 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KIY47912.1 - 1.6e-15 56.8 6.4 3.2e-15 55.9 6.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KIY47912.1 - 3e-08 33.4 0.0 5.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 KIY47912.1 - 2.3e-05 24.4 0.9 5.2e-05 23.2 0.9 1.7 1 0 0 1 1 1 1 WW domain Vps36-NZF-N PF16988.5 KIY47912.1 - 0.013 14.9 0.3 0.025 13.9 0.3 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RSRP PF17069.5 KIY47913.1 - 0.21 11.1 15.1 0.31 10.6 15.1 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Melibiase_2 PF16499.5 KIY47914.1 - 2.3e-56 191.1 3.0 3.1e-56 190.6 3.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIY47914.1 - 3.2e-14 52.7 0.6 1.1e-13 51.0 0.7 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIY47914.1 - 0.063 12.2 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Melibiase ATP-synt_10 PF05176.14 KIY47915.1 - 2.8e-49 167.7 0.0 3.6e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein ELYS PF13934.6 KIY47916.1 - 6e-37 127.8 1.2 7.3e-37 127.5 1.2 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly KDZ PF18758.1 KIY47919.1 - 2.3e-24 86.3 0.0 2.5e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Methyltransf_2 PF00891.18 KIY47920.1 - 8.3e-12 44.8 0.0 3e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KIY47920.1 - 0.003 17.1 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KIY47920.1 - 0.049 14.4 0.0 0.082 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KIY47922.1 - 5.1e-14 52.1 0.0 1.4e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KIY47922.1 - 0.0048 16.5 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KIY47922.1 - 0.063 14.0 0.0 0.091 13.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain CBS PF00571.28 KIY47923.1 - 1.9e-15 57.0 0.1 0.023 15.1 0.0 4.5 4 0 0 4 4 4 4 CBS domain PITH PF06201.13 KIY47924.1 - 1.3e-25 90.4 0.0 1.6e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain ABC_tran PF00005.27 KIY47925.1 - 1.2e-35 123.0 0.2 3.6e-18 66.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIY47925.1 - 3e-11 43.7 1.4 0.11 12.3 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY47925.1 - 3.3e-11 43.0 4.7 0.0023 17.4 0.1 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY47925.1 - 2.7e-07 31.1 0.0 0.036 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY47925.1 - 1.2e-05 25.2 0.2 0.041 13.8 0.1 2.8 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 KIY47925.1 - 1.8e-05 24.7 0.3 0.0056 16.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KIY47925.1 - 5.4e-05 23.6 0.0 0.21 12.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIY47925.1 - 0.00016 21.4 0.1 0.52 10.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY47925.1 - 0.00029 21.1 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KIY47925.1 - 0.00041 20.2 1.1 0.74 9.5 0.5 2.7 3 1 0 3 3 2 2 AAA ATPase domain SbcCD_C PF13558.6 KIY47925.1 - 0.0005 20.3 0.1 1.7 9.0 0.0 3.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KIY47925.1 - 0.00088 18.5 0.0 0.31 10.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.6 KIY47925.1 - 0.0013 19.0 0.2 0.44 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KIY47925.1 - 0.0018 17.9 1.8 0.26 10.9 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KIY47925.1 - 0.0037 17.3 0.9 0.15 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KIY47925.1 - 0.0042 17.0 0.0 0.57 10.1 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KIY47925.1 - 0.0042 17.2 0.6 0.75 10.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KIY47925.1 - 0.0066 16.2 0.4 1 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIY47925.1 - 0.0077 16.6 0.0 3.8 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 KIY47925.1 - 0.0088 16.0 0.1 0.23 11.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KIY47925.1 - 0.011 15.3 1.5 0.053 13.0 0.2 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 KIY47925.1 - 0.011 14.4 2.4 0.025 13.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KIY47925.1 - 0.012 15.4 0.2 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIY47925.1 - 0.013 16.0 7.7 0.053 14.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KIY47925.1 - 0.014 15.6 0.4 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KIY47925.1 - 0.03 14.4 0.6 8.1 6.6 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY47925.1 - 0.034 14.7 0.1 6.1 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIY47925.1 - 0.041 13.3 0.3 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 KIY47925.1 - 0.054 12.8 0.2 0.88 8.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DLIC PF05783.11 KIY47925.1 - 0.077 11.8 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TniB PF05621.11 KIY47925.1 - 0.088 12.2 0.1 1.4 8.3 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein Thymidylate_kin PF02223.17 KIY47925.1 - 0.12 12.0 0.1 19 4.9 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase PduV-EutP PF10662.9 KIY47925.1 - 0.2 11.4 1.9 0.41 10.4 0.0 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KIY47925.1 - 0.31 10.9 1.4 19 5.1 0.1 3.2 3 0 0 3 3 3 0 NTPase AAA_14 PF13173.6 KIY47925.1 - 0.35 10.9 2.1 12 5.9 0.1 3.2 2 2 1 3 3 3 0 AAA domain Nucleos_tra2_C PF07662.13 KIY47926.1 - 1.1e-68 231.1 2.8 1.1e-68 231.1 2.8 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KIY47926.1 - 9.3e-22 77.4 5.8 9.3e-22 77.4 5.8 3.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KIY47926.1 - 0.13 12.5 23.3 0.063 13.6 7.9 3.5 3 1 0 3 3 3 0 Nucleoside recognition F-box-like PF12937.7 KIY47928.1 - 9e-11 41.5 7.1 1.1e-10 41.2 2.3 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY47928.1 - 3.9 7.5 7.5 8.5 6.4 0.2 3.0 3 0 0 3 3 3 0 F-box domain Phosphodiest PF01663.22 KIY47930.1 - 2.2e-18 67.0 1.4 1.4e-17 64.4 0.1 2.5 2 1 1 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF997 PF06196.12 KIY47932.1 - 0.038 14.0 0.9 0.038 14.0 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF997) PEP-utilisers_N PF05524.13 KIY47935.1 - 0.028 14.6 0.9 0.061 13.5 0.9 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Spc7 PF08317.11 KIY47935.1 - 0.13 11.1 0.5 0.2 10.5 0.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 KIY47935.1 - 0.26 11.0 3.0 0.25 11.1 1.8 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PI3K_1B_p101 PF10486.9 KIY47938.1 - 0.5 8.1 3.7 0.67 7.7 3.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sporozoite_P67 PF05642.11 KIY47939.1 - 0.052 11.6 6.9 0.064 11.3 6.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tet_JBP PF12851.7 KIY47943.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily p450 PF00067.22 KIY47946.1 - 6.8e-24 84.4 0.1 2.3e-23 82.7 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 Pep1_7 PF17232.2 KIY47947.1 - 8.9 6.9 10.9 1.9 9.0 1.3 3.3 4 0 0 4 4 4 0 Elicitor peptide 1-7 Plavaka PF18759.1 KIY47948.1 - 3.9e-34 118.4 0.1 5.4e-34 117.9 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Alpha-amylase PF00128.24 KIY47954.1 - 1.2e-19 71.1 0.0 2.8e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIY47954.1 - 6.6e-11 42.5 0.2 2e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain HHH_8 PF14716.6 KIY47956.1 - 0.041 14.2 0.1 0.15 12.5 0.1 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain SIMPL PF04402.14 KIY47956.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) KDZ PF18758.1 KIY47957.1 - 2.2e-22 79.8 0.0 3.3e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY47957.1 - 0.03 14.5 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY47957.1 - 0.039 14.1 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY47957.1 - 0.093 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases 2OG-FeII_Oxy_3 PF13640.6 KIY47958.1 - 0.008 17.0 0.0 0.015 16.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2827 PF10933.8 KIY47959.1 - 0.0047 15.7 0.1 0.0072 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2827) DUF4201 PF13870.6 KIY47959.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Retrotran_gag_2 PF14223.6 KIY47962.1 - 3.4e-14 52.7 0.0 4.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIY47962.1 - 0.022 14.6 0.1 0.037 13.8 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Methyltransf_3 PF01596.17 KIY47963.1 - 2.2e-17 63.0 0.0 2.5e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIY47963.1 - 0.00073 20.5 0.0 0.0013 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY47963.1 - 0.0015 18.3 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PNPase_C PF12111.8 KIY47963.1 - 0.16 11.4 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal NeA_P2 PF12312.8 KIY47964.1 - 8.2 5.8 8.1 1.1 8.7 1.2 2.1 1 1 1 2 2 2 0 Nepovirus subgroup A polyprotein PT PF04886.12 KIY47965.1 - 3e-07 29.9 36.4 0.0041 16.6 3.8 4.4 3 2 0 3 3 3 2 PT repeat Imm51 PF15595.6 KIY47965.1 - 0.031 14.2 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 51 Plavaka PF18759.1 KIY47966.1 - 8.3e-110 367.0 0.0 1.1e-109 366.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase baeRF_family6 PF18848.1 KIY47966.1 - 0.13 12.7 0.1 1.1 9.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 6 YopD PF05844.12 KIY47969.1 - 0.034 13.1 0.9 0.054 12.5 0.1 1.8 2 0 0 2 2 2 0 YopD protein SseB_C PF14581.6 KIY47969.1 - 0.15 12.1 0.0 0.53 10.4 0.0 1.9 1 1 1 2 2 2 0 SseB protein C-terminal domain TFIIA_gamma_N PF02268.16 KIY47974.1 - 5.8e-05 23.0 0.0 0.63 10.1 0.0 2.7 2 0 0 2 2 2 2 Transcription initiation factor IIA, gamma subunit, helical domain Elf-1_N PF12310.8 KIY47974.1 - 0.077 13.5 0.1 14 6.3 0.0 2.8 3 0 0 3 3 3 0 Transcription factor protein N terminal Retrotrans_gag PF03732.17 KIY47975.1 - 0.0022 18.2 0.2 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein NYD-SP28_assoc PF14775.6 KIY47975.1 - 0.15 12.2 1.1 0.44 10.7 0.1 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain CxC1 PF18802.1 KIY47979.1 - 0.00054 20.1 0.4 0.00077 19.6 0.2 1.4 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIY47979.1 - 0.035 14.3 0.1 0.043 14.0 0.1 1.2 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY47979.1 - 0.13 12.1 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY47980.1 - 2.4e-39 135.2 0.0 3.2e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Ribosomal_L23eN PF03939.13 KIY47980.1 - 5.5 7.3 5.9 13 6.1 0.3 2.4 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain P33MONOX PF15302.6 KIY47981.1 - 0.03 14.1 0.2 0.031 14.0 0.2 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase Spt46 PF17734.1 KIY47981.1 - 0.043 13.6 0.4 0.051 13.4 0.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 SnoaL_2 PF12680.7 KIY47982.1 - 0.078 13.6 0.2 0.11 13.2 0.2 1.3 1 0 0 1 1 1 0 SnoaL-like domain Tri3 PF07428.11 KIY47984.1 - 0.021 13.8 0.0 0.61 8.9 0.0 2.1 1 1 0 1 1 1 0 15-O-acetyltransferase Tri3 ComX PF05952.12 KIY47984.1 - 0.13 12.2 0.5 0.43 10.6 0.1 2.0 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Gp-FAR-1 PF05823.12 KIY47986.1 - 0.0064 16.9 0.3 0.63 10.4 0.3 2.0 1 1 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4254 PF14063.6 KIY47986.1 - 0.026 14.4 0.1 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) HMG_box_2 PF09011.10 KIY47986.1 - 0.026 15.1 0.0 0.05 14.2 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain Phage_integrase PF00589.22 KIY47988.1 - 0.00088 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF3684 PF12449.8 KIY47988.1 - 0.025 12.4 0.0 0.034 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) gag-asp_proteas PF13975.6 KIY47989.1 - 2.8e-06 27.8 0.0 4.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIY47989.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 KIY47989.1 - 0.012 16.3 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF5500 PF17604.2 KIY47991.1 - 0.57 10.3 3.3 37 4.5 0.0 4.2 3 2 1 4 4 4 0 Family of unknown function (DUF5500) Amidase PF01425.21 KIY47995.1 - 0.00086 18.4 0.5 0.00091 18.3 0.5 1.1 1 0 0 1 1 1 1 Amidase AAA-ATPase_like PF09820.9 KIY47997.1 - 3.6e-17 62.7 0.0 5.1e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Predicted AAA-ATPase Glyco_transf_7C PF02709.14 KIY47997.1 - 0.037 13.7 0.3 0.57 9.9 0.1 2.6 2 1 0 2 2 2 0 N-terminal domain of galactosyltransferase DNA_pol_phi PF04931.13 KIY47997.1 - 4.6 5.2 6.7 6.9 4.6 6.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi DNA_pol_phi PF04931.13 KIY47998.1 - 0.43 8.6 6.8 0.54 8.3 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KIY47998.1 - 4.4 7.0 10.2 5.8 6.6 10.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Phage_int_SAM_1 PF02899.17 KIY48000.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Aldo_ket_red PF00248.21 KIY48002.1 - 2.2e-10 40.2 0.0 2.2e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family KNOX2 PF03791.13 KIY48002.1 - 0.026 14.0 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 KNOX2 domain zf-CDGSH PF09360.10 KIY48002.1 - 0.12 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Iron-binding zinc finger CDGSH type gag_pre-integrs PF13976.6 KIY48003.1 - 8.9e-10 38.3 0.1 1.2e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain HTH_Tnp_Tc5 PF03221.16 KIY48004.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Metallopep PF12044.8 KIY48005.1 - 1.4e-21 76.6 0.2 1.1e-07 30.8 0.0 3.4 1 1 2 3 3 3 3 Putative peptidase family Rft-1 PF04506.13 KIY48007.1 - 3e-47 161.5 9.5 2.3e-45 155.3 6.0 2.0 1 1 1 2 2 2 2 Rft protein Zmiz1_N PF18028.1 KIY48008.1 - 0.11 12.8 0.1 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain WD40 PF00400.32 KIY48009.1 - 3.1e-18 65.8 4.8 4e-06 27.5 0.5 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY48009.1 - 7.4e-05 23.0 0.3 0.0009 19.5 0.1 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIY48009.1 - 0.00061 19.6 3.1 0.0012 18.6 3.1 1.5 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIY48009.1 - 0.016 13.8 1.5 0.02 13.5 0.6 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 IKI3 PF04762.12 KIY48009.1 - 0.12 10.4 0.4 1.8 6.5 0.3 1.9 1 1 1 2 2 2 0 IKI3 family Coatomer_WDAD PF04053.14 KIY48009.1 - 0.26 10.3 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region DNApol_Exo PF18136.1 KIY48010.1 - 0.083 12.0 0.1 0.099 11.8 0.1 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Phage_int_SAM_3 PF14659.6 KIY48013.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Exo_endo_phos PF03372.23 KIY48016.1 - 0.0034 17.0 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SRX PF09201.10 KIY48017.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit DAO PF01266.24 KIY48018.1 - 1.7e-27 96.9 0.2 3.3e-26 92.7 0.2 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY48018.1 - 0.031 14.5 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY48018.1 - 0.039 13.9 0.0 0.09 12.8 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KIY48018.1 - 0.22 11.8 0.0 0.38 11.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Protoglobin PF11563.8 KIY48019.1 - 1.1e-33 116.4 0.0 1.2e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Protoglobin A_deaminase PF00962.22 KIY48020.1 - 3e-05 23.5 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3-RhoG_link PF16609.5 KIY48022.1 - 0.011 15.5 1.4 0.014 15.1 1.0 1.3 1 1 0 1 1 1 0 SH3-RhoGEF linking unstructured region DUF4599 PF15371.6 KIY48022.1 - 3.5 8.2 6.0 14 6.3 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4599) Retrotran_gag_2 PF14223.6 KIY48024.1 - 1.3e-17 63.7 0.0 2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type S36_mt PF10937.8 KIY48025.1 - 0.037 15.6 0.9 0.053 15.1 0.9 1.2 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial BTB PF00651.31 KIY48026.1 - 3.4e-05 24.0 0.0 4.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2489 PF10675.9 KIY48027.1 - 0.0041 17.0 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2489) PRELI PF04707.14 KIY48028.1 - 1.7e-39 135.2 0.0 2e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Lipoprotein_6 PF01441.19 KIY48029.1 - 0.053 13.5 0.1 0.08 12.9 0.1 1.2 1 0 0 1 1 1 0 Lipoprotein Clathrin_lg_ch PF01086.17 KIY48030.1 - 6.9e-45 153.9 1.7 8.5e-45 153.6 1.7 1.1 1 0 0 1 1 1 1 Clathrin light chain FKBP_N PF01346.18 KIY48030.1 - 4.8 8.2 8.0 8.2 7.5 5.4 2.4 2 1 1 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase PGP_phosphatase PF09419.10 KIY48031.1 - 1.9e-42 144.8 0.0 2.3e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KIY48031.1 - 0.025 14.6 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like F-box-like PF12937.7 KIY48032.1 - 3.2e-08 33.3 0.3 7.8e-08 32.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY48032.1 - 7.5e-08 32.1 0.6 1.6e-07 31.0 0.6 1.6 1 0 0 1 1 1 1 F-box domain DUF3294 PF07957.11 KIY48033.1 - 0.049 13.4 3.8 0.4 10.4 3.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3294) NES_C_h PF18208.1 KIY48033.1 - 0.15 12.3 3.2 0.33 11.2 3.2 1.6 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain AA_permease PF00324.21 KIY48034.1 - 1.1e-113 380.4 33.6 1.3e-113 380.2 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY48034.1 - 1.4e-34 119.7 35.5 1.7e-34 119.4 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease zf-rbx1 PF12678.7 KIY48035.1 - 1e-13 51.4 5.7 1.8e-13 50.6 5.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIY48035.1 - 6.4e-11 42.4 6.8 1.5e-10 41.2 6.8 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY48035.1 - 2.5e-07 30.6 3.2 6.1e-07 29.4 3.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY48035.1 - 3e-07 30.2 4.0 5.6e-07 29.3 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY48035.1 - 5.6e-07 29.5 0.7 1.1e-06 28.5 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KIY48035.1 - 3.1e-06 26.9 4.0 3.1e-06 26.9 4.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY48035.1 - 5.4e-05 23.0 4.6 0.001 18.8 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY48035.1 - 7.8e-05 22.6 3.1 0.00017 21.4 3.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY48035.1 - 0.00016 21.4 3.7 0.00042 20.1 3.7 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIY48035.1 - 0.00073 19.1 1.5 0.0016 18.0 1.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KIY48035.1 - 0.0024 17.6 1.7 0.0024 17.6 1.7 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KIY48035.1 - 0.0062 16.7 1.4 0.015 15.5 1.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING POX PF07526.11 KIY48035.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Associated with HOX FANCL_C PF11793.8 KIY48035.1 - 0.046 13.9 1.0 0.098 12.8 1.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KIY48035.1 - 0.23 11.8 3.7 0.44 10.9 3.7 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KIY48035.1 - 0.65 9.8 2.5 0.63 9.9 0.8 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YqeY PF09424.10 KIY48036.1 - 2.8e-24 85.8 4.5 3.1e-24 85.7 4.5 1.0 1 0 0 1 1 1 1 Yqey-like protein YtzH PF14165.6 KIY48036.1 - 0.018 15.4 0.2 8.5 6.8 0.1 2.8 2 1 1 3 3 3 0 YtzH-like protein SpoVIF PF14069.6 KIY48036.1 - 0.077 12.8 0.8 0.24 11.2 0.8 1.8 1 0 0 1 1 1 0 Stage VI sporulation protein F YusW PF14039.6 KIY48036.1 - 0.099 13.2 0.6 0.36 11.4 0.1 2.2 2 1 1 3 3 3 0 YusW-like protein CTV_P23 PF04808.12 KIY48036.1 - 0.14 11.7 1.5 0.47 10.0 0.3 1.8 1 1 1 2 2 2 0 Citrus tristeza virus (CTV) P23 protein DUF3983 PF13137.6 KIY48036.1 - 0.61 9.9 4.4 0.24 11.3 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) Amidohydro_3 PF07969.11 KIY48037.1 - 7.5e-82 276.3 0.5 9.6e-82 275.9 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIY48037.1 - 2.9e-13 49.9 0.0 1.6e-12 47.4 0.0 2.1 2 1 0 2 2 2 1 Amidohydrolase family SNF2_N PF00176.23 KIY48038.1 - 3.4e-54 183.9 0.0 7e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY48038.1 - 1.5e-12 47.9 0.0 5.9e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY48038.1 - 3.4e-10 40.2 0.0 9.8e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY48038.1 - 9.9e-06 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2439 PF10382.9 KIY48038.1 - 0.00013 22.2 0.5 0.21 11.9 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2439) SWI2_SNF2 PF18766.1 KIY48038.1 - 0.0082 15.8 1.3 0.018 14.8 0.0 2.2 2 1 0 2 2 2 1 SWI2/SNF2 ATPase Voltage_CLC PF00654.20 KIY48041.1 - 3.5e-86 289.7 37.2 3.5e-86 289.7 37.2 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KIY48041.1 - 1.2e-10 41.6 2.5 5.2e-06 26.8 0.1 2.7 2 0 0 2 2 2 2 CBS domain F-box-like PF12937.7 KIY48041.1 - 0.2 11.6 0.9 0.5 10.3 0.1 2.1 2 0 0 2 2 2 0 F-box-like Abhydrolase_6 PF12697.7 KIY48043.1 - 2.1e-16 61.2 0.5 3e-16 60.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY48043.1 - 1.2e-14 54.6 0.3 4e-14 52.9 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY48043.1 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIY48043.1 - 0.0078 14.9 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Atg14 PF10186.9 KIY48044.1 - 1.4e-46 159.1 0.0 1.9e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Dynactin_p22 PF07426.11 KIY48044.1 - 0.12 12.2 1.0 0.18 11.6 1.0 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 zf-B_box PF00643.24 KIY48044.1 - 0.84 9.8 3.9 1.3 9.2 3.9 1.3 1 0 0 1 1 1 0 B-box zinc finger PIG-U PF06728.13 KIY48045.1 - 1.2e-100 337.2 25.6 1.4e-100 337.0 25.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U zf-C2H2 PF00096.26 KIY48046.1 - 6.4e-08 32.6 13.0 0.0036 17.7 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY48046.1 - 0.00021 21.9 11.7 0.36 11.8 0.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY48046.1 - 0.0011 19.3 12.0 0.029 14.8 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIY48046.1 - 0.11 12.2 15.6 0.065 13.0 2.8 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain LETM1 PF07766.13 KIY48047.1 - 4.7e-15 55.7 0.4 7.2e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 LETM1-like protein O-FucT PF10250.9 KIY48048.1 - 8.3e-19 68.5 0.0 1.2e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 KIY48048.1 - 0.048 12.9 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 11 DUF4083 PF13314.6 KIY48049.1 - 0.052 13.5 0.3 0.098 12.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) COX14 PF14880.6 KIY48049.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Gti1_Pac2 PF09729.9 KIY48050.1 - 1.8e-23 83.5 0.0 4.9e-21 75.6 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family pP_pnuc_1 PF18165.1 KIY48051.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease Aldo_ket_red PF00248.21 KIY48052.1 - 1.7e-70 237.5 0.0 2.2e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family G-alpha PF00503.20 KIY48053.1 - 2.3e-120 402.0 0.1 2.7e-120 401.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY48053.1 - 1.8e-16 60.1 1.3 1.1e-11 44.6 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY48053.1 - 4.2e-05 23.0 1.2 0.0023 17.3 0.0 2.5 2 1 0 3 3 3 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KIY48053.1 - 0.0037 17.5 0.4 3.1 8.0 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 KIY48053.1 - 0.038 13.8 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger AAA_29 PF13555.6 KIY48053.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIY48053.1 - 0.058 13.5 0.0 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY48053.1 - 0.086 12.4 0.0 6.1 6.3 0.0 2.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KIY48053.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family N2227 PF07942.12 KIY48057.1 - 3.2e-97 325.0 0.0 4.4e-97 324.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KIY48057.1 - 0.00083 20.1 0.2 0.0035 18.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY48057.1 - 0.001 18.9 0.0 0.0067 16.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY48057.1 - 0.022 15.4 0.0 0.82 10.4 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_3 PF00933.21 KIY48058.1 - 2.3e-49 168.5 0.0 3.1e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KIY48058.1 - 1.1e-44 152.9 0.0 1.9e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIY48058.1 - 3.8e-22 78.2 1.1 7.9e-22 77.2 1.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Bac_rhamnosid6H PF17389.2 KIY48060.1 - 3.7e-11 42.9 1.4 3.3e-10 39.8 1.4 2.0 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 KIY48060.1 - 0.002 17.1 0.1 0.0043 16.0 0.1 1.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid_C PF17390.2 KIY48060.1 - 0.0088 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KIY48060.1 - 0.021 13.7 0.3 0.03 13.1 0.3 1.1 1 0 0 1 1 1 0 Trehalase Sugar_tr PF00083.24 KIY48062.1 - 1.8e-102 343.6 17.0 2.2e-102 343.3 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY48062.1 - 1.3e-16 60.5 23.1 1.3e-16 60.5 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIY48062.1 - 0.0052 15.1 0.8 0.014 13.7 0.8 1.7 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 KIY48062.1 - 0.67 8.9 9.2 0.11 11.4 3.1 2.2 2 0 0 2 2 2 0 PUCC protein SnoaL_2 PF12680.7 KIY48063.1 - 0.0001 22.9 0.0 0.00013 22.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain WI12 PF07107.11 KIY48063.1 - 0.0083 16.2 0.0 0.02 15.0 0.0 1.7 1 1 1 2 2 2 1 Wound-induced protein WI12 UDPGT PF00201.18 KIY48064.1 - 9e-10 37.9 0.1 9e-10 37.9 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIY48064.1 - 0.2 11.6 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Oxidored_FMN PF00724.20 KIY48065.1 - 7.5e-75 252.3 0.0 9e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KIY48065.1 - 0.14 11.6 0.0 0.87 9.0 0.0 2.2 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF4405 PF14358.6 KIY48066.1 - 0.55 10.8 4.2 1.4 9.5 0.2 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) Sulfate_transp PF00916.20 KIY48067.1 - 7.8e-09 34.8 1.0 1.2e-08 34.1 1.0 1.2 1 0 0 1 1 1 1 Sulfate permease family Exonuc_VII_L PF02601.15 KIY48068.1 - 6.7 6.2 7.7 12 5.3 7.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KIY48068.1 - 7 5.4 5.2 13 4.6 5.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1289 PF06945.13 KIY48070.1 - 0.012 15.4 1.3 0.027 14.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) NDC10_II PF16787.5 KIY48071.1 - 0.19 10.7 0.1 0.36 9.8 0.1 1.4 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 TPK_catalytic PF04263.16 KIY48072.1 - 1.3e-29 102.7 0.0 1.8e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KIY48072.1 - 2.1e-05 24.1 0.1 3.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NHL PF01436.21 KIY48072.1 - 0.0063 16.5 1.5 0.012 15.7 0.8 1.9 2 0 0 2 2 2 1 NHL repeat ANAPC4_WD40 PF12894.7 KIY48073.1 - 2.4e-15 56.6 0.3 1.3e-06 28.6 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY48073.1 - 5.1e-15 55.6 36.5 1.4e-05 25.7 0.6 9.9 10 1 0 10 10 10 3 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 KIY48073.1 - 0.0026 17.1 0.0 0.011 15.0 0.0 2.0 1 1 1 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 KIY48073.1 - 0.0036 17.2 0.1 1.2 9.2 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIY48073.1 - 0.015 14.2 1.8 1.4 7.8 0.1 3.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 KIY48073.1 - 0.049 13.0 0.0 0.32 10.3 0.0 2.2 1 1 2 3 3 3 0 CPSF A subunit region DUF5114 PF17141.4 KIY48073.1 - 0.14 12.7 0.6 1.5 9.4 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF5114) ADH_zinc_N PF00107.26 KIY48074.1 - 1e-23 83.7 0.2 2.3e-23 82.6 0.2 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY48074.1 - 4.5e-11 43.9 0.0 8.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY48074.1 - 5.3e-05 23.0 0.0 0.00026 20.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain CENP-X PF09415.10 KIY48075.1 - 0.26 11.6 0.2 0.26 11.6 0.2 2.2 2 0 0 2 2 2 0 CENP-S associating Centromere protein X RNA_pol_A_bac PF01000.26 KIY48076.1 - 3.8e-22 78.8 0.0 7.7e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KIY48076.1 - 2.6e-17 62.0 0.0 3.6e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_Phos_2 PF00328.22 KIY48077.1 - 0.43 9.9 1.1 83 2.3 0.2 3.5 3 1 1 4 4 4 0 Histidine phosphatase superfamily (branch 2) Cdd1 PF11731.8 KIY48080.1 - 0.04 14.2 0.1 0.075 13.3 0.1 1.4 1 0 0 1 1 1 0 Pathogenicity locus EPOP PF15223.6 KIY48080.1 - 0.22 10.8 0.1 0.31 10.4 0.1 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein CHS5_N PF16892.5 KIY48081.1 - 8.5e-24 83.3 0.1 1.3e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus fn3_2 PF16893.5 KIY48081.1 - 1.1e-15 57.5 0.1 1.7e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 KIY48081.1 - 0.0052 17.0 0.0 0.0064 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3_2 PF16893.5 KIY48082.1 - 3.3e-10 40.0 0.1 9.4e-10 38.5 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain BRCT PF00533.26 KIY48082.1 - 1.4e-08 35.0 0.0 2.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIY48082.1 - 2.4e-07 30.6 0.0 1.3e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KIY48082.1 - 0.002 18.5 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain STAS PF01740.21 KIY48084.1 - 3.6e-06 26.6 0.0 6.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 KIY48084.1 - 7.3e-06 25.0 0.3 9.9e-06 24.5 0.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 KIY48084.1 - 0.022 15.1 1.1 0.046 14.1 0.0 2.0 2 0 0 2 2 2 0 STAS domain FA_desaturase PF00487.24 KIY48087.1 - 5e-28 98.6 23.6 7.5e-28 98.0 23.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIY48087.1 - 0.01 16.1 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) GPI-anchored PF10342.9 KIY48089.1 - 6.5e-10 39.6 1.3 6.5e-10 39.6 1.3 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tmemb_cc2 PF10267.9 KIY48089.1 - 1.8 7.6 5.3 1.9 7.5 5.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein HsbA PF12296.8 KIY48090.1 - 0.00048 20.5 6.8 0.00066 20.1 6.8 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A LXG PF04740.12 KIY48090.1 - 0.005 16.6 2.1 0.34 10.6 0.7 2.1 1 1 1 2 2 2 2 LXG domain of WXG superfamily VP4_helical PF17478.2 KIY48090.1 - 0.032 13.7 4.3 0.04 13.4 4.3 1.2 1 0 0 1 1 1 0 Rotavirus VP4 helical domain Gemini_AC4_5_2 PF08464.10 KIY48090.1 - 0.14 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region FA_desaturase PF00487.24 KIY48091.1 - 5.6e-24 85.3 30.2 1.8e-23 83.7 30.2 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIY48091.1 - 0.0037 17.5 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) PMT_4TMC PF16192.5 KIY48092.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MBOAT_2 PF13813.6 KIY48092.1 - 0.028 14.7 0.2 0.078 13.3 0.2 1.7 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Thaumatin PF00314.17 KIY48097.1 - 7.1e-72 241.5 12.5 8.1e-72 241.3 12.5 1.0 1 0 0 1 1 1 1 Thaumatin family PPC PF04151.15 KIY48097.1 - 0.018 16.1 1.6 0.032 15.3 0.4 2.1 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Ada3 PF10198.9 KIY48098.1 - 3.6e-23 82.2 10.2 3.6e-23 82.2 10.2 2.3 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 HAUS-augmin3 PF14932.6 KIY48098.1 - 0.17 11.5 8.1 2 7.9 2.4 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 SCIMP PF15050.6 KIY48098.1 - 3 8.3 6.3 1.2 9.6 1.8 2.4 2 0 0 2 2 2 0 SCIMP protein FAD_binding_4 PF01565.23 KIY48099.1 - 1.6e-17 63.6 0.1 2.7e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY48099.1 - 5.4e-11 42.4 0.7 1.3e-10 41.2 0.7 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KIY48100.1 - 3.6e-42 144.0 0.1 4.8e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY48100.1 - 4.6e-34 118.0 0.1 6.6e-34 117.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY48100.1 - 6.4e-12 45.7 0.0 4.4e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY48100.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY48100.1 - 0.043 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KIY48100.1 - 0.15 12.0 0.1 1.3 8.9 0.0 2.3 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_2 PF00891.18 KIY48101.1 - 6.9e-20 71.2 0.0 8.8e-18 64.4 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_31 PF13847.6 KIY48101.1 - 0.008 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY48101.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY48101.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KIY48101.1 - 0.057 12.9 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 KIY48101.1 - 0.079 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIY48101.1 - 0.093 13.4 0.0 0.25 12.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Retrotran_gag_2 PF14223.6 KIY48102.1 - 4.7e-08 32.8 0.0 7.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DDE_1 PF03184.19 KIY48103.1 - 7.7e-08 32.2 0.0 9.3e-06 25.4 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease LisH_TPL PF17814.1 KIY48103.1 - 0.024 14.3 0.1 0.042 13.5 0.1 1.3 1 0 0 1 1 1 0 LisH-like dimerisation domain L_lactis_ph-MCP PF06673.11 KIY48108.1 - 0.052 12.5 0.2 0.084 11.9 0.1 1.3 1 1 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein BRF1 PF07741.13 KIY48108.1 - 0.71 10.3 4.7 1.5 9.3 4.7 1.6 1 1 0 1 1 1 0 Brf1-like TBP-binding domain MBD_C PF14048.6 KIY48111.1 - 0.13 13.0 0.0 0.14 12.9 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Med31 PF05669.12 KIY48113.1 - 8.9e-05 22.4 8.0 0.00019 21.3 8.0 1.6 1 1 0 1 1 1 1 SOH1 Cdc6_C PF09079.11 KIY48113.1 - 0.35 10.9 3.1 5.2 7.1 0.2 2.9 1 1 2 3 3 3 0 CDC6, C terminal winged helix domain Plavaka PF18759.1 KIY48117.1 - 6.4e-101 337.8 4.9 8.9e-101 337.3 4.9 1.2 1 0 0 1 1 1 1 Plavaka transposase Zn_clus PF00172.18 KIY48118.1 - 0.13 12.4 3.5 1.5 9.0 0.5 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_C PF00034.21 KIY48119.1 - 3.3e-11 44.2 0.0 5.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KIY48119.1 - 4.7e-08 33.2 2.6 4e-07 30.3 2.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KIY48119.1 - 0.00048 19.9 0.9 0.0019 17.9 0.9 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 KIY48119.1 - 0.056 14.1 0.0 0.058 14.0 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.9 KIY48119.1 - 0.09 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 HAUS6_N PF14661.6 KIY48120.1 - 3.8e-05 23.4 0.1 0.00026 20.7 0.1 1.9 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Epimerase PF01370.21 KIY48120.1 - 0.081 12.4 0.0 0.095 12.1 0.0 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 KIY48122.1 - 1.4e-08 34.5 4.0 2e-08 34.0 1.8 2.5 2 0 0 2 2 2 1 F-box-like FCD PF07729.12 KIY48123.1 - 0.48 10.9 4.7 0.55 10.7 2.0 2.0 2 0 0 2 2 2 0 FCD domain UQ_con PF00179.26 KIY48124.1 - 7e-18 64.6 0.0 1.1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Herpes_UL56 PF04534.12 KIY48124.1 - 0.065 12.7 0.3 0.12 11.8 0.3 1.5 1 1 0 1 1 1 0 Herpesvirus UL56 protein SHNi-TPR PF10516.9 KIY48125.1 - 6.1e-17 60.8 2.3 8.5e-15 53.9 0.2 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.6 KIY48125.1 - 6.1e-11 42.5 9.8 1e-05 25.7 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY48125.1 - 4.2e-08 32.7 4.8 0.0046 16.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY48125.1 - 1.5e-07 31.0 6.6 0.018 15.1 2.8 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY48125.1 - 0.0003 20.4 6.0 0.083 12.6 1.1 3.0 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 KIY48125.1 - 0.0024 17.9 4.1 1.6 9.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIY48125.1 - 0.0074 16.1 2.1 7.9 6.5 0.4 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY48125.1 - 0.0098 15.9 0.8 6.6 7.0 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY48125.1 - 0.075 13.5 8.9 3.4 8.2 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY48125.1 - 0.13 12.9 12.9 2.8 8.7 4.7 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KIY48125.1 - 0.49 10.1 4.8 2.1 8.0 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain NOA36 PF06524.12 KIY48125.1 - 1 8.6 5.4 1.6 8.0 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein MIT PF04212.18 KIY48125.1 - 2.7 8.1 12.4 0.28 11.3 3.0 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain LSM PF01423.22 KIY48126.1 - 1.2e-16 60.1 0.0 1.9e-16 59.5 0.0 1.3 1 1 0 1 1 1 1 LSM domain LAL_C2 PF18603.1 KIY48126.1 - 0.0019 18.3 0.0 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 CreD PF06123.12 KIY48127.1 - 0.042 12.6 2.1 0.043 12.6 2.1 1.0 1 0 0 1 1 1 0 Inner membrane protein CreD DUF2721 PF11026.8 KIY48127.1 - 0.083 12.8 4.8 0.1 12.5 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF3377 PF11857.8 KIY48128.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) EII-Sor PF03609.14 KIY48128.1 - 0.83 9.0 10.5 1.4 8.3 10.5 1.3 1 0 0 1 1 1 0 PTS system sorbose-specific iic component TctB PF07331.11 KIY48128.1 - 5.5 7.3 9.8 11 6.3 9.8 1.5 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family PGK PF00162.19 KIY48129.1 - 1.4e-146 488.3 0.0 1.6e-146 488.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase YjbH PF06082.11 KIY48130.1 - 0.39 9.5 8.0 0.5 9.1 8.0 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH MAT1 PF06391.13 KIY48130.1 - 3 7.6 11.1 3.9 7.2 11.1 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 MSA-2c PF12238.8 KIY48130.1 - 9.6 6.1 6.8 28 4.6 0.0 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c Bcr-Abl_Oligo PF09036.10 KIY48131.1 - 0.12 12.4 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain GGDEF_2 PF17853.1 KIY48132.1 - 0.098 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 GGDEF-like domain BRAP2 PF07576.12 KIY48133.1 - 2.3e-29 101.5 0.0 4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KIY48133.1 - 2.7e-19 69.2 3.2 7.7e-19 67.8 3.2 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KIY48133.1 - 1.1e-08 35.2 9.6 1.1e-08 35.2 9.6 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY48133.1 - 2.2e-06 27.4 9.6 6e-06 26.0 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY48133.1 - 6.3e-06 25.8 4.2 1.9e-05 24.3 4.2 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KIY48133.1 - 9.8e-06 25.8 6.2 2.9e-05 24.3 6.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIY48133.1 - 2.6e-05 24.2 5.6 9.6e-05 22.3 5.5 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY48133.1 - 6.5e-05 22.7 7.8 6.5e-05 22.7 7.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY48133.1 - 0.00056 19.7 6.5 0.00056 19.7 6.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KIY48133.1 - 0.00082 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.6 KIY48133.1 - 0.0011 18.8 6.9 0.0011 18.8 6.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIY48133.1 - 0.0012 18.9 2.7 0.0024 17.9 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KIY48133.1 - 0.0028 17.4 6.2 0.0084 15.9 6.2 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Syntaxin-6_N PF09177.11 KIY48133.1 - 0.032 14.8 13.8 0.47 11.0 3.6 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4763 PF15960.5 KIY48133.1 - 0.034 13.5 13.2 0.052 12.8 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) AAA_23 PF13476.6 KIY48133.1 - 0.049 14.1 8.8 0.08 13.4 8.8 1.3 1 0 0 1 1 1 0 AAA domain zf-UBP_var PF17807.1 KIY48133.1 - 0.084 12.6 0.4 0.2 11.5 0.4 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger Exonuc_VII_L PF02601.15 KIY48133.1 - 0.24 11.0 6.6 0.37 10.3 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2968 PF11180.8 KIY48133.1 - 0.28 10.8 22.8 0.46 10.1 13.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) DUF1664 PF07889.12 KIY48133.1 - 0.33 11.0 11.1 2 8.5 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 KIY48133.1 - 1.2 9.1 21.1 2.1 8.4 21.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RasGAP_C PF03836.15 KIY48133.1 - 1.5 9.0 16.4 0.054 13.6 5.1 2.2 1 1 1 2 2 2 0 RasGAP C-terminus TerY_C PF15616.6 KIY48133.1 - 4.9 7.3 11.3 1.5 9.0 3.3 2.5 2 0 0 2 2 2 0 TerY-C metal binding domain Prok-RING_4 PF14447.6 KIY48133.1 - 9.4 6.2 21.8 1.1 9.1 11.2 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 EMP24_GP25L PF01105.24 KIY48134.1 - 8.2e-50 169.3 0.1 9.3e-50 169.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD YscO PF07321.12 KIY48134.1 - 0.01 15.8 0.5 0.015 15.3 0.5 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO IL1 PF00340.19 KIY48134.1 - 0.024 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Interleukin-1 / 18 INCA1 PF15142.6 KIY48134.1 - 0.051 13.6 0.2 0.082 12.9 0.2 1.3 1 0 0 1 1 1 0 INCA1 MCU PF04678.13 KIY48134.1 - 0.058 13.5 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Tropomyosin_1 PF12718.7 KIY48135.1 - 1.7e-45 154.7 34.5 1.9e-45 154.5 34.5 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KIY48135.1 - 4.6e-08 32.7 33.8 8.1e-05 22.1 5.2 3.0 1 1 2 3 3 3 3 Tropomyosin Uso1_p115_C PF04871.13 KIY48135.1 - 7.9e-05 23.0 16.6 7.9e-05 23.0 16.6 2.2 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4200 PF13863.6 KIY48135.1 - 0.002 18.5 31.0 0.041 14.3 15.5 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Fez1 PF06818.15 KIY48135.1 - 0.0074 16.8 25.5 0.22 12.0 14.2 2.2 1 1 1 2 2 2 2 Fez1 GAS PF13851.6 KIY48135.1 - 0.0098 15.3 31.3 0.033 13.6 11.4 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KIY48135.1 - 0.01 15.9 7.8 0.01 15.9 7.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KELK PF15796.5 KIY48135.1 - 0.02 15.3 6.6 0.02 15.3 6.6 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Cep57_CLD_2 PF14197.6 KIY48135.1 - 0.036 14.2 29.0 1 9.5 5.6 3.3 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Atg14 PF10186.9 KIY48135.1 - 0.039 13.0 24.8 0.39 9.7 6.7 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 KIY48135.1 - 0.042 14.1 34.8 0.017 15.3 21.5 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HHV-5_US34A PF17087.5 KIY48135.1 - 0.049 13.8 3.7 0.049 13.8 3.7 2.8 2 1 1 3 3 3 0 Herpesvirus US34A protein family ERM PF00769.19 KIY48135.1 - 0.077 12.8 36.8 0.12 12.2 34.2 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Transketolase_N PF00456.21 KIY48135.1 - 0.087 11.8 6.8 0.11 11.5 6.8 1.0 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain EzrA PF06160.12 KIY48135.1 - 0.09 10.9 24.7 0.028 12.6 11.9 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF724 PF05266.14 KIY48135.1 - 0.13 12.1 25.8 0.54 10.1 7.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 KIY48135.1 - 0.15 9.5 31.9 0.12 9.8 15.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) BRE1 PF08647.11 KIY48135.1 - 0.23 11.6 29.3 0.043 13.9 11.8 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase APG17 PF04108.12 KIY48135.1 - 0.27 10.3 19.6 0.054 12.6 2.2 3.0 1 1 2 3 3 3 0 Autophagy protein Apg17 HGD-D PF06050.13 KIY48135.1 - 0.28 10.9 4.8 0.23 11.2 3.6 1.4 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component TPR_MLP1_2 PF07926.12 KIY48135.1 - 0.4 10.8 36.2 0.5 10.4 9.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 KIY48135.1 - 0.41 8.7 27.9 0.48 8.5 27.9 1.1 1 0 0 1 1 1 0 HOOK protein DUF3450 PF11932.8 KIY48135.1 - 0.53 9.5 29.3 1.7 7.9 16.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 KIY48135.1 - 0.61 8.9 25.6 0.97 8.2 25.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FPP PF05911.11 KIY48135.1 - 0.63 8.2 26.0 0.77 7.9 26.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 KIY48135.1 - 0.68 9.2 25.1 1.1 8.5 25.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KIY48135.1 - 0.74 9.8 32.1 0.048 13.7 9.3 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 KIY48135.1 - 0.76 9.9 31.0 0.23 11.5 16.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF5082 PF16888.5 KIY48135.1 - 0.8 10.0 17.3 7.2 6.9 0.5 3.6 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) AAA_13 PF13166.6 KIY48135.1 - 0.88 8.1 20.6 1.3 7.6 20.6 1.2 1 0 0 1 1 1 0 AAA domain CdvA PF18822.1 KIY48135.1 - 1 9.2 25.4 1 9.2 16.8 2.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain ADIP PF11559.8 KIY48135.1 - 1.1 9.4 30.4 2.2 8.4 7.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KIY48135.1 - 1.2 9.7 40.7 2.4 8.7 26.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Csm1_N PF18504.1 KIY48135.1 - 1.5 9.3 30.0 0.29 11.5 9.1 3.8 1 1 2 3 3 3 0 Csm1 N-terminal domain Sec2p PF06428.11 KIY48135.1 - 1.9 8.5 28.0 5.9 6.9 9.1 4.0 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF3552 PF12072.8 KIY48135.1 - 2.1 7.7 32.1 8.8 5.7 19.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 KIY48135.1 - 2.1 7.2 32.5 1.3 7.8 15.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FliJ PF02050.16 KIY48135.1 - 2.6 8.3 31.1 5.7 7.2 15.8 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein Tup_N PF08581.10 KIY48135.1 - 2.6 8.4 26.2 0.12 12.7 4.4 3.0 1 1 2 3 3 3 0 Tup N-terminal Alanine_zipper PF11839.8 KIY48135.1 - 3.6 8.0 15.0 1.2 9.5 0.4 3.4 3 1 0 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein DHR10 PF18595.1 KIY48135.1 - 3.7 7.6 38.5 1.4 9.0 16.1 3.1 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF4061 PF13270.6 KIY48135.1 - 4.1 7.8 19.1 6 7.3 5.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4061) Syntaxin_2 PF14523.6 KIY48135.1 - 4.5 7.7 16.6 0.51 10.7 10.7 2.1 1 1 1 2 2 2 0 Syntaxin-like protein FemAB PF02388.16 KIY48135.1 - 5.7 5.7 23.0 1.4 7.8 8.8 2.0 1 1 1 2 2 2 0 FemAB family DUF641 PF04859.12 KIY48135.1 - 5.7 7.3 21.6 1.6 9.1 3.9 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) LMBR1 PF04791.16 KIY48135.1 - 5.9 5.7 14.2 7.9 5.3 14.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Laminin_II PF06009.12 KIY48135.1 - 6.2 6.8 17.0 0.29 11.2 1.2 2.5 1 1 1 2 2 2 0 Laminin Domain II FAM76 PF16046.5 KIY48135.1 - 6.3 6.1 20.5 0.6 9.4 10.6 2.1 1 1 1 2 2 2 0 FAM76 protein ALS2CR11 PF15729.5 KIY48135.1 - 6.4 5.8 12.2 8.7 5.4 12.2 1.3 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Prominin PF05478.11 KIY48135.1 - 6.4 4.6 11.1 7.7 4.3 11.1 1.1 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 KIY48135.1 - 6.8 6.2 21.8 42 3.6 21.8 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Phage_lysozyme2 PF18013.1 KIY48135.1 - 7.8 6.5 9.9 25 4.9 9.9 1.8 1 1 0 1 1 1 0 Phage tail lysozyme TMF_TATA_bd PF12325.8 KIY48135.1 - 8 6.7 28.4 28 5.0 15.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 KIY48135.1 - 9.3 6.6 34.6 32 4.8 20.2 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DHHC PF01529.20 KIY48136.1 - 2.1e-18 66.7 9.9 7.5e-18 64.9 6.6 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Mit_KHE1 PF10173.9 KIY48136.1 - 0.15 12.1 0.2 0.24 11.5 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TPPK_C PF12555.8 KIY48136.1 - 0.16 12.1 0.3 0.16 12.1 0.3 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal MFS_1 PF07690.16 KIY48136.1 - 0.37 9.7 9.0 0.41 9.5 0.0 2.7 2 1 0 2 2 2 0 Major Facilitator Superfamily PQ-loop PF04193.14 KIY48137.1 - 1.1e-26 92.4 13.4 9.7e-14 50.9 1.4 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 KIY48137.1 - 4.5e-05 23.4 9.9 0.02 14.9 1.0 2.6 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange HGWP PF03578.15 KIY48137.1 - 0.0016 17.9 0.3 0.0039 16.7 0.3 1.6 1 0 0 1 1 1 1 HGWP repeat ER_lumen_recept PF00810.18 KIY48137.1 - 0.0029 18.4 3.2 0.016 16.0 1.6 2.2 1 1 1 2 2 2 1 ER lumen protein retaining receptor DBI_PRT PF02277.17 KIY48137.1 - 0.0049 16.1 0.0 0.0065 15.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyltransferase Pro_isomerase PF00160.21 KIY48138.1 - 5.9e-39 133.9 1.8 1.4e-38 132.7 0.0 2.4 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 KIY48138.1 - 0.068 13.6 0.1 0.068 13.6 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) Methyltransf_11 PF08241.12 KIY48139.1 - 7.2e-10 39.4 0.0 1.4e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY48139.1 - 8.7e-09 36.0 0.0 1.5e-08 35.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY48139.1 - 9.2e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIY48139.1 - 0.12 12.0 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Arylsulfotran_2 PF14269.6 KIY48140.1 - 5.7e-61 206.5 4.5 9.1e-61 205.8 4.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY48140.1 - 1.8e-13 50.2 0.7 2.5e-12 46.4 0.6 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) SelR PF01641.18 KIY48142.1 - 1.3e-51 173.7 0.0 1.5e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 KIY48142.1 - 0.025 14.8 0.0 3.1 8.1 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I zinc_ribbon_10 PF10058.9 KIY48142.1 - 0.027 14.2 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Mss51 PF13824.6 KIY48142.1 - 0.11 12.6 1.6 0.42 10.7 0.3 2.5 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Gly-zipper_Omp PF13488.6 KIY48143.1 - 0.0083 16.1 0.4 1.2 9.1 0.1 2.3 2 0 0 2 2 2 2 Glycine zipper ADK PF00406.22 KIY48144.1 - 4.8e-44 150.1 0.6 6.7e-43 146.4 0.6 2.0 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIY48144.1 - 1.2e-31 109.9 0.1 2.1e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY48144.1 - 1.2e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY48144.1 - 1.3e-06 28.9 0.0 2.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KIY48144.1 - 5.4e-05 22.9 0.3 0.00041 20.1 0.3 2.0 1 1 0 1 1 1 1 Thymidylate kinase Ploopntkinase3 PF18751.1 KIY48144.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KIY48144.1 - 0.19 11.0 1.4 2.5 7.4 0.2 2.6 2 1 1 3 3 3 0 Zeta toxin RTP1_C1 PF10363.9 KIY48145.1 - 5e-37 126.5 0.4 4.8e-34 116.9 0.0 3.6 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KIY48145.1 - 0.00059 19.5 0.1 0.002 17.8 0.1 2.0 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Tti2 PF10521.9 KIY48145.1 - 0.023 14.3 0.3 4.4 6.8 0.0 2.9 2 0 0 2 2 2 0 Tti2 family Urb2 PF10441.9 KIY48145.1 - 0.04 13.8 5.0 0.073 13.0 1.2 3.2 3 1 0 3 3 3 0 Urb2/Npa2 family HEAT_2 PF13646.6 KIY48145.1 - 0.043 14.2 2.9 2 8.9 0.1 3.8 4 0 0 4 4 4 0 HEAT repeats MMS19_N PF14500.6 KIY48145.1 - 0.066 12.8 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Use1 PF09753.9 KIY48145.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 Plavaka PF18759.1 KIY48146.1 - 3.3e-15 56.1 0.1 3.3e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase UCR_UQCRX_QCR9 PF05365.12 KIY48146.1 - 0.03 14.3 1.6 0.12 12.3 0.3 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Plavaka PF18759.1 KIY48147.1 - 6.8e-42 143.8 0.0 7.3e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Co_AT_N PF12557.8 KIY48147.1 - 0.012 15.5 0.4 0.019 14.9 0.4 1.3 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Plavaka PF18759.1 KIY48148.1 - 1.2e-28 100.3 0.0 1.3e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase DUF3960 PF13142.6 KIY48149.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) DUF3288 PF11691.8 KIY48152.1 - 0.043 13.8 0.4 0.46 10.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) N2227 PF07942.12 KIY48152.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 N2227-like protein SLAM PF06214.11 KIY48155.1 - 0.0086 16.1 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Signaling lymphocytic activation molecule (SLAM) protein Wtap PF17098.5 KIY48155.1 - 0.058 13.3 0.1 0.091 12.7 0.1 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family DUF3990 PF13151.6 KIY48157.1 - 8e-05 22.4 0.0 9.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) BaffR-Tall_bind PF09256.10 KIY48157.1 - 0.42 10.4 0.2 0.42 10.4 0.2 1.8 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding DDE_3 PF13358.6 KIY48159.1 - 0.029 14.1 0.2 0.57 9.9 0.0 2.3 2 1 0 2 2 2 0 DDE superfamily endonuclease Cation_ATPase_C PF00689.21 KIY48162.1 - 1.6e-16 60.6 10.1 3.7e-13 49.6 0.5 3.3 3 1 1 4 4 4 2 Cation transporting ATPase, C-terminus Mak10 PF04112.13 KIY48168.1 - 9.9e-40 135.8 0.0 2e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Tmemb_40 PF10160.9 KIY48168.1 - 0.085 12.3 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein HhH-GPD PF00730.25 KIY48169.1 - 2.7e-18 66.4 0.0 5e-18 65.5 0.0 1.4 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIY48169.1 - 0.0042 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Pkinase PF00069.25 KIY48170.1 - 1.5e-49 168.7 0.0 2.6e-49 168.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48170.1 - 3.5e-25 88.8 0.0 7.6e-25 87.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY48170.1 - 0.0043 15.9 0.1 0.0062 15.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIY48170.1 - 0.016 14.9 0.4 0.35 10.5 0.4 2.1 1 1 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KIY48170.1 - 0.019 14.0 0.1 0.027 13.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_hydro38C2 PF17677.1 KIY48170.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain APH PF01636.23 KIY48170.1 - 0.072 13.0 0.1 0.39 10.6 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY48170.1 - 0.14 11.5 0.2 0.28 10.5 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Extensin_2 PF04554.13 KIY48171.1 - 0.22 11.6 31.1 0.25 11.4 14.4 3.1 4 0 0 4 4 4 0 Extensin-like region Adaptin_N PF01602.20 KIY48173.1 - 4.7e-86 289.4 7.6 8.3e-86 288.6 7.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KIY48173.1 - 4e-60 201.4 0.0 1.2e-59 199.9 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KIY48173.1 - 2.5e-54 183.0 0.1 7.1e-54 181.5 0.1 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT PF02985.22 KIY48173.1 - 6.8e-08 32.1 1.2 0.19 12.1 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KIY48173.1 - 8.5e-08 32.5 0.5 0.08 13.3 0.0 4.7 3 1 0 4 4 4 2 HEAT repeats Coatomer_g_Cpla PF16381.5 KIY48173.1 - 7.8e-05 22.8 0.0 0.0019 18.3 0.0 3.0 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform Cnd1 PF12717.7 KIY48173.1 - 0.0017 18.4 11.6 0.0044 17.1 0.0 4.4 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Gemini_V2 PF01524.17 KIY48173.1 - 0.037 14.2 0.0 0.83 9.9 0.0 2.7 2 0 0 2 2 2 0 Geminivirus V2 protein RTP1_C1 PF10363.9 KIY48173.1 - 0.082 13.1 2.1 0.89 9.8 0.0 3.3 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 KIY48173.1 - 0.16 12.4 5.3 1.3 9.4 0.0 4.3 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ParcG PF10274.9 KIY48173.1 - 0.3 11.2 5.3 0.83 9.8 0.0 3.4 4 0 0 4 4 4 0 Parkin co-regulated protein HSP20 PF00011.21 KIY48174.1 - 9e-06 25.8 0.0 1.1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY48174.1 - 0.098 12.2 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 HSP20-like domain found in ArsA DEAD PF00270.29 KIY48175.1 - 3.4e-44 150.7 0.0 5.9e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY48175.1 - 5e-25 88.0 0.0 7.3e-24 84.3 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIY48175.1 - 6.2e-20 71.2 0.4 1.5e-19 70.0 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIY48175.1 - 0.0029 17.6 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KIY48175.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.5 1 1 0 1 1 1 0 SecA DEAD-like domain SWI2_SNF2 PF18766.1 KIY48175.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Methyltransf_23 PF13489.6 KIY48176.1 - 4.8e-07 29.7 0.0 6.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY48176.1 - 0.00018 22.2 0.0 0.001 19.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY48176.1 - 0.0002 22.0 0.0 0.00056 20.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY48176.1 - 0.00053 20.6 0.0 0.0015 19.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY48176.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KIY48176.1 - 0.051 13.2 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein S (NodS) Pox_MCEL PF03291.16 KIY48176.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_2 PF00891.18 KIY48176.1 - 0.14 11.4 0.0 0.77 9.0 0.0 1.9 1 1 1 2 2 2 0 O-methyltransferase domain CRM1_repeat PF18777.1 KIY48176.1 - 0.22 11.0 0.3 0.45 10.1 0.3 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat F-box-like PF12937.7 KIY48177.1 - 6.8e-09 35.5 0.4 1.4e-08 34.4 0.4 1.6 1 0 0 1 1 1 1 F-box-like Lipase_3 PF01764.25 KIY48178.1 - 6.2e-07 29.4 0.0 1.7e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY48178.1 - 0.022 15.4 0.2 0.043 14.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 KIY48178.1 - 0.067 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Glyco_hydro_31 PF01055.26 KIY48179.1 - 1.4e-148 495.8 8.5 1.8e-148 495.4 8.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIY48179.1 - 7.9e-36 122.8 0.1 1.6e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIY48179.1 - 1.7e-14 53.9 0.3 7.6e-14 51.8 0.3 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like DUF1788 PF08747.11 KIY48179.1 - 0.14 12.1 0.0 0.56 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) Sulfate_transp PF00916.20 KIY48180.1 - 0.0014 17.5 0.2 0.002 17.0 0.2 1.1 1 0 0 1 1 1 1 Sulfate permease family adh_short PF00106.25 KIY48181.1 - 2.3e-19 69.6 0.0 1.4e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY48181.1 - 4.1e-09 36.3 0.0 8.5e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY48181.1 - 0.0004 20.3 0.0 0.00087 19.2 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY48181.1 - 0.014 14.9 0.2 0.033 13.7 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1080 PF06439.11 KIY48181.1 - 0.063 13.4 0.0 0.47 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) Sacchrp_dh_NADP PF03435.18 KIY48181.1 - 0.09 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cdd1 PF11731.8 KIY48181.1 - 0.69 10.2 2.3 22 5.4 0.0 2.7 3 0 0 3 3 3 0 Pathogenicity locus Pkinase_fungal PF17667.1 KIY48182.1 - 5.2e-14 51.8 0.0 3.8e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIY48182.1 - 0.00059 19.3 0.0 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48182.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Megourin PF17560.2 KIY48182.1 - 0.03 14.5 0.3 0.076 13.3 0.3 1.6 1 0 0 1 1 1 0 Aphid Megourins CAP_GLY PF01302.25 KIY48183.1 - 4.9e-24 84.1 2.2 6.9e-24 83.7 2.2 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KIY48183.1 - 1.5e-21 76.6 0.0 2.4e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KIY48183.1 - 0.012 15.4 0.1 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family SHS2_Rpb7-N PF03876.17 KIY48185.1 - 5e-10 39.6 0.0 7.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 adh_short PF00106.25 KIY48186.1 - 3.3e-21 75.7 0.0 6.2e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY48186.1 - 2.4e-11 43.6 0.0 5.3e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY48186.1 - 6.9e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY48186.1 - 0.042 13.3 0.2 0.066 12.7 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIY48186.1 - 0.075 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KIY48187.1 - 1.5e-16 60.5 0.0 2.9e-15 56.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY48187.1 - 2.6e-11 43.5 0.0 5.1e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY48187.1 - 0.029 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 KR domain WSC PF01822.19 KIY48189.1 - 3.5e-15 55.9 12.1 4.9e-15 55.5 12.1 1.2 1 0 0 1 1 1 1 WSC domain GH3 PF03321.13 KIY48190.1 - 0.14 11.0 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter PP2C PF00481.21 KIY48191.1 - 1.5e-27 96.8 0.0 3.7e-26 92.3 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C F-box-like PF12937.7 KIY48192.1 - 4.8e-07 29.6 0.4 1.4e-06 28.0 0.2 2.0 2 0 0 2 2 2 1 F-box-like Furin-like_2 PF15913.5 KIY48194.1 - 9.1e-08 32.2 12.6 9.1e-08 32.2 12.6 7.4 1 1 5 7 7 7 3 Furin-like repeat, cysteine-rich VSP PF03302.13 KIY48194.1 - 2.4e-07 30.0 168.7 0.00035 19.6 27.7 7.0 1 1 6 7 7 7 5 Giardia variant-specific surface protein GF_recep_IV PF14843.6 KIY48194.1 - 1.4e-05 24.9 61.6 0.00039 20.2 35.0 6.3 1 1 6 7 7 7 5 Growth factor receptor domain IV Furin-like PF00757.20 KIY48194.1 - 0.0034 17.3 31.3 0.0034 17.3 31.3 5.9 1 1 4 5 5 5 1 Furin-like cysteine rich region EGF_2 PF07974.13 KIY48194.1 - 0.0055 17.0 10.8 0.0055 17.0 10.8 11.8 11 4 1 13 13 13 1 EGF-like domain DUF4381 PF14316.6 KIY48194.1 - 0.017 15.3 2.3 0.03 14.5 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Saf_2TM PF18303.1 KIY48194.1 - 0.058 13.0 0.1 0.097 12.3 0.1 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain F-box-like PF12937.7 KIY48195.1 - 1.3e-08 34.6 0.8 3.5e-08 33.2 0.8 1.8 1 0 0 1 1 1 1 F-box-like RTA1 PF04479.13 KIY48196.1 - 0.009 15.6 0.6 0.011 15.4 0.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Mem_trans PF03547.18 KIY48196.1 - 0.033 12.6 0.5 0.072 11.5 0.1 1.6 1 1 1 2 2 2 0 Membrane transport protein Ank_4 PF13637.6 KIY48197.1 - 4.7e-12 46.2 0.2 5.4e-08 33.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY48197.1 - 7.1e-07 29.4 0.2 2.1e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY48197.1 - 6.5e-05 23.5 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIY48197.1 - 0.0009 19.6 0.0 0.0023 18.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KIY48197.1 - 0.032 14.8 0.0 0.52 11.1 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeat MFS_1 PF07690.16 KIY48200.1 - 1.7e-40 139.0 30.1 1.7e-40 139.0 30.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY48200.1 - 2e-07 30.3 12.7 2e-07 30.3 12.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KIY48200.1 - 0.0046 15.3 1.1 0.0046 15.3 1.1 2.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF4213 PF13938.6 KIY48200.1 - 0.19 12.0 7.6 0.69 10.2 0.6 3.6 3 1 0 3 3 3 0 Putative heavy-metal chelation CPP1-like PF11833.8 KIY48200.1 - 3.3 7.3 15.7 2.2 7.9 0.7 2.9 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Calcipressin PF04847.12 KIY48201.1 - 2.5e-34 118.6 0.0 3.1e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Calcipressin HNH_2 PF13391.6 KIY48203.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease DUF4515 PF14988.6 KIY48203.1 - 0.04 13.8 0.4 0.063 13.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) CDC37_M PF08565.11 KIY48205.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain IFT20 PF14931.6 KIY48207.1 - 0.099 12.8 0.8 0.18 12.0 0.8 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Calcipressin PF04847.12 KIY48208.1 - 7.8e-07 29.0 1.0 1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Calcipressin Transposon_TraM PF12508.8 KIY48208.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Conjugative transposon, TraM adh_short PF00106.25 KIY48210.1 - 2.3e-29 102.3 0.0 1.4e-25 89.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY48210.1 - 1.6e-19 70.4 0.0 9.8e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY48210.1 - 9.9e-10 38.6 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY48210.1 - 8.6e-05 22.1 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY48210.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Methyltransf_PK PF05891.12 KIY48210.1 - 0.002 17.7 0.5 0.099 12.1 0.5 2.1 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Polysacc_synt_2 PF02719.15 KIY48210.1 - 0.0035 16.5 0.2 0.0095 15.1 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 KIY48210.1 - 0.0058 17.0 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KIY48210.1 - 0.016 15.4 0.1 0.027 14.8 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIY48210.1 - 0.024 14.7 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ccdc124 PF06244.12 KIY48212.1 - 4.7e-28 98.3 15.4 1.3e-27 96.9 15.4 1.8 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 p450 PF00067.22 KIY48213.1 - 9.2e-39 133.5 0.0 1.1e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DinI PF06183.13 KIY48213.1 - 0.13 12.6 0.1 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 DinI-like family p450 PF00067.22 KIY48214.1 - 1e-45 156.4 0.0 1.3e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2781 PF10914.8 KIY48215.1 - 1.5e-28 100.1 12.1 1.7e-28 99.9 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ABC_tran PF00005.27 KIY48216.1 - 1.4e-43 148.7 0.0 1.4e-21 77.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KIY48216.1 - 4.7e-41 140.5 35.7 1.4e-23 83.4 13.6 2.6 2 0 0 2 2 2 2 ABC-2 type transporter AAA_29 PF13555.6 KIY48216.1 - 8.7e-09 35.0 2.4 0.0014 18.3 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KIY48216.1 - 4.3e-08 32.8 0.2 0.0029 17.1 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIY48216.1 - 5.7e-08 32.8 0.9 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KIY48216.1 - 3.1e-07 31.1 4.0 0.0042 17.6 0.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIY48216.1 - 7.4e-07 29.7 3.3 0.0074 16.7 0.1 2.8 2 1 1 3 3 2 2 AAA ATPase domain PDR_assoc PF08370.11 KIY48216.1 - 1.4e-06 27.9 0.2 4.8e-06 26.2 0.2 2.0 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_21 PF13304.6 KIY48216.1 - 5.5e-06 26.4 1.1 1.2 8.9 0.2 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KIY48216.1 - 1.1e-05 25.7 0.0 0.28 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIY48216.1 - 1.1e-05 25.1 0.1 0.021 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIY48216.1 - 0.00014 22.4 0.2 0.079 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY48216.1 - 0.00024 20.9 1.1 0.69 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KIY48216.1 - 0.00055 19.1 0.9 0.079 12.0 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 KIY48216.1 - 0.00062 20.1 0.3 0.89 10.0 0.0 2.4 2 0 0 2 2 2 2 RNA helicase cobW PF02492.19 KIY48216.1 - 0.00078 19.1 1.1 0.085 12.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KIY48216.1 - 0.0026 17.7 0.6 0.12 12.2 0.3 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 KIY48216.1 - 0.0043 17.4 0.7 1.2 9.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIY48216.1 - 0.0071 16.6 2.5 0.21 11.8 0.6 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY48216.1 - 0.0075 16.4 1.5 2.6 8.2 0.3 2.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KIY48216.1 - 0.0079 15.9 1.3 9 5.9 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.17 KIY48216.1 - 0.0085 15.9 1.6 0.33 10.7 0.3 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 KIY48216.1 - 0.011 15.1 1.7 0.37 10.1 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KIY48216.1 - 0.016 14.9 0.7 2.7 7.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIY48216.1 - 0.02 14.9 4.5 1.5 8.9 0.4 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 KIY48216.1 - 0.024 14.4 1.5 0.6 9.8 0.2 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 KIY48216.1 - 0.025 14.1 1.7 0.098 12.1 0.2 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 KIY48216.1 - 0.043 13.1 0.4 9 5.5 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KIY48216.1 - 0.047 13.6 0.1 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CPSase_sm_chain PF00988.22 KIY48216.1 - 0.05 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain AAA_7 PF12775.7 KIY48216.1 - 0.065 12.8 0.7 4.9 6.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 KIY48216.1 - 0.079 12.9 0.1 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Thymidylate_kin PF02223.17 KIY48216.1 - 0.083 12.6 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Dynamin_N PF00350.23 KIY48216.1 - 0.1 12.6 1.8 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.14 KIY48216.1 - 0.11 12.5 0.3 23 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 KIY48216.1 - 0.12 12.1 0.9 0.89 9.2 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 KIY48216.1 - 0.12 12.8 0.5 5.7 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIY48216.1 - 0.17 11.8 0.7 9.2 6.1 0.2 2.9 3 0 0 3 3 3 0 NTPase IIGP PF05049.13 KIY48216.1 - 0.43 9.6 1.6 2.6 7.0 0.2 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) APS_kinase PF01583.20 KIY48216.1 - 0.52 10.2 1.6 18 5.2 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase MeaB PF03308.16 KIY48216.1 - 3.8 6.4 4.2 1.8 7.4 0.1 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KIY48216.1 - 6.4 6.8 6.5 4.9 7.2 1.7 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Defb50 PF17546.2 KIY48217.1 - 0.2 11.6 0.5 0.39 10.7 0.5 1.4 1 0 0 1 1 1 0 Beta defensin 50 C2 PF00168.30 KIY48218.1 - 8e-12 45.4 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain Cnn_1N PF07989.11 KIY48219.1 - 1.7e-22 79.3 7.7 1.7e-22 79.3 7.7 12.4 6 2 4 11 11 11 2 Centrosomin N-terminal motif 1 ZapB PF06005.12 KIY48219.1 - 0.0019 18.6 5.4 0.0019 18.6 5.4 13.0 2 2 7 9 9 9 1 Cell division protein ZapB Spc7 PF08317.11 KIY48219.1 - 0.002 17.1 18.3 0.002 17.1 18.3 7.4 2 2 6 8 8 8 3 Spc7 kinetochore protein DUF4200 PF13863.6 KIY48219.1 - 0.0022 18.4 14.5 0.0022 18.4 14.5 9.7 4 3 7 11 11 11 1 Domain of unknown function (DUF4200) GAS PF13851.6 KIY48219.1 - 0.0035 16.7 15.8 0.0035 16.7 15.8 8.1 2 2 5 8 8 8 3 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KIY48219.1 - 0.0074 16.8 19.2 0.0074 16.8 19.2 7.6 1 1 4 5 5 5 1 Fez1 HIP1_clath_bdg PF16515.5 KIY48219.1 - 0.0099 16.5 1.6 0.0099 16.5 1.6 11.0 4 2 6 10 10 10 3 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5344 PF17279.2 KIY48219.1 - 0.012 16.1 0.8 0.012 16.1 0.8 6.8 8 2 1 9 9 9 0 Family of unknown function (DUF5344) Pribosyltran_N PF13793.6 KIY48220.1 - 1e-49 167.3 0.3 3.8e-49 165.5 0.1 2.1 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KIY48220.1 - 2.4e-35 122.2 0.8 2.7e-33 115.6 0.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KIY48220.1 - 1.4e-17 63.6 1.5 1.8e-15 56.8 0.3 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 KIY48220.1 - 0.0017 17.8 0.1 0.0028 17.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AA_kinase PF00696.28 KIY48221.1 - 5.9e-38 130.8 1.0 7.8e-38 130.4 1.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KIY48221.1 - 1.3e-11 44.3 0.2 3e-11 43.1 0.1 1.7 2 0 0 2 2 2 1 PUA domain CENP-Q PF13094.6 KIY48222.1 - 0.07 13.3 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TGS PF02824.21 KIY48223.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 TGS domain DOPA_dioxygen PF08883.11 KIY48228.1 - 1.4e-30 105.7 0.0 1.8e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family ADH_N PF08240.12 KIY48230.1 - 3.6e-24 84.7 1.4 5.8e-24 84.1 1.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY48230.1 - 7.6e-24 84.1 0.3 1.6e-23 83.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY48230.1 - 4.9e-10 40.6 0.0 9.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KIY48230.1 - 0.059 12.8 0.1 0.096 12.1 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.25 KIY48231.1 - 1.6e-20 73.4 0.5 1.1e-18 67.5 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY48231.1 - 4e-10 39.6 0.3 1.5e-09 37.8 0.3 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY48231.1 - 1.4e-07 31.6 0.1 2.3e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Adeno_PIX PF03955.14 KIY48231.1 - 0.14 12.4 0.5 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Polysacc_synt_2 PF02719.15 KIY48231.1 - 0.19 10.8 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ABC_tran PF00005.27 KIY48232.1 - 3.8e-45 153.8 0.0 4e-21 76.0 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIY48232.1 - 1.3e-17 64.6 1.6 1.5e-06 28.3 0.2 4.5 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY48232.1 - 1.5e-13 50.7 0.2 0.00058 19.4 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIY48232.1 - 9.5e-08 31.7 0.2 0.015 15.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY48232.1 - 1e-05 26.0 1.2 0.034 14.5 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain DUF87 PF01935.17 KIY48232.1 - 1.1e-05 25.7 0.1 0.0048 17.0 0.0 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain Chromo PF00385.24 KIY48232.1 - 1.4e-05 24.9 0.2 3.3e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RsgA_GTPase PF03193.16 KIY48232.1 - 3e-05 24.0 0.0 0.089 12.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIY48232.1 - 4.7e-05 23.4 0.0 0.27 11.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KIY48232.1 - 5.2e-05 23.5 0.0 0.26 11.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KIY48232.1 - 8.6e-05 22.9 0.2 0.47 10.9 0.0 3.0 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 KIY48232.1 - 0.00015 22.3 0.0 0.46 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KIY48232.1 - 0.00022 21.6 0.0 3.5 8.1 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIY48232.1 - 0.00031 20.7 0.1 0.77 9.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 KIY48232.1 - 0.00033 21.2 10.8 0.0063 17.0 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KIY48232.1 - 0.00036 20.8 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIY48232.1 - 0.00064 19.9 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KIY48232.1 - 0.00083 18.4 0.4 0.29 10.1 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KIY48232.1 - 0.00093 18.8 0.3 0.85 9.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region HEAT_2 PF13646.6 KIY48232.1 - 0.0014 19.0 14.7 0.0027 18.1 0.3 3.9 2 1 0 2 2 2 1 HEAT repeats AAA_15 PF13175.6 KIY48232.1 - 0.0027 17.5 4.2 0.28 10.9 0.0 2.8 3 1 0 3 3 2 2 AAA ATPase domain 4HB PF17947.1 KIY48232.1 - 0.0048 16.9 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_24 PF13479.6 KIY48232.1 - 0.0065 16.2 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KIY48232.1 - 0.0094 15.1 0.2 2.8 7.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 KIY48232.1 - 0.02 14.6 1.5 4.9 6.8 0.2 3.2 3 0 0 3 3 2 0 AAA domain AAA_13 PF13166.6 KIY48232.1 - 0.022 13.5 0.0 2 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIY48232.1 - 0.026 14.5 0.1 9.1 6.1 0.0 3.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Roc PF08477.13 KIY48232.1 - 0.027 14.7 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 KIY48232.1 - 0.038 14.2 0.1 2.9 8.2 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit HBS1_N PF08938.10 KIY48232.1 - 0.04 14.2 1.9 9.3 6.6 0.3 4.0 4 0 0 4 4 3 0 HBS1 N-terminus NB-ARC PF00931.22 KIY48232.1 - 0.041 13.1 0.0 5.9 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 KIY48232.1 - 0.044 13.8 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KIY48232.1 - 0.069 13.2 0.1 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 KIY48232.1 - 0.09 12.7 0.1 11 5.8 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_27 PF13514.6 KIY48232.1 - 0.1 12.2 0.1 11 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KIY48232.1 - 0.1 12.4 1.3 13 5.5 0.0 2.9 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MMS19_C PF12460.8 KIY48232.1 - 0.17 11.0 2.3 0.28 10.2 0.1 2.0 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal cobW PF02492.19 KIY48232.1 - 0.34 10.5 2.2 15 5.1 0.1 3.3 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KIY48232.1 - 1.2 9.1 4.7 19 5.3 0.1 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) F-box-like PF12937.7 KIY48233.1 - 2e-08 34.0 0.2 2e-08 34.0 0.2 2.4 2 0 0 2 2 2 1 F-box-like CENP-T_C PF15511.6 KIY48234.1 - 3.7e-07 30.2 0.0 4.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIY48234.1 - 8.2e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIY48234.1 - 0.00016 22.0 0.0 0.00021 21.6 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY48234.1 - 0.0012 19.1 0.1 0.0024 18.1 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY48234.1 - 0.0025 18.2 0.1 0.0028 18.0 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIY48234.1 - 0.07 13.2 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.20 KIY48235.1 - 5.7e-25 87.3 0.0 7e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIY48235.1 - 2e-07 31.4 0.0 9.5e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIY48235.1 - 1e-05 25.8 0.0 0.0093 16.3 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KIY48235.1 - 4.4e-05 23.2 0.0 5.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KIY48235.1 - 0.00056 19.4 0.0 0.00066 19.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KIY48235.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KIY48235.1 - 0.0031 17.7 0.1 0.0058 16.8 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KIY48235.1 - 0.008 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 KIY48235.1 - 0.052 13.3 0.2 0.35 10.6 0.0 1.9 1 1 1 2 2 2 0 Redoxin DIM1 PF02966.16 KIY48235.1 - 0.084 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF2847 PF11009.8 KIY48235.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Glycos_transf_1 PF00534.20 KIY48236.1 - 5.3e-23 81.4 0.0 3.2e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIY48236.1 - 2e-16 60.5 0.5 3.9e-16 59.5 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KIY48236.1 - 1.8e-08 34.9 0.0 1.2e-05 25.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIY48236.1 - 9e-08 32.7 3.1 1e-07 32.6 0.2 2.4 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain DUF2607 PF10795.9 KIY48236.1 - 0.043 14.0 0.5 0.11 12.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) Per1 PF04080.13 KIY48237.1 - 3.1e-98 328.6 15.9 3.6e-98 328.4 15.9 1.0 1 0 0 1 1 1 1 Per1-like family Ceramidase PF05875.12 KIY48237.1 - 0.0025 17.3 10.6 0.038 13.4 10.6 2.0 1 1 0 1 1 1 1 Ceramidase Hist_deacetyl PF00850.19 KIY48238.1 - 1.7e-84 284.0 0.1 2.1e-84 283.6 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain F-box-like PF12937.7 KIY48240.1 - 8.4e-05 22.4 3.0 0.00021 21.1 1.8 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY48240.1 - 0.17 12.3 0.2 6.4 7.4 0.0 3.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 KIY48241.1 - 1.2e-24 86.9 0.0 2.5e-23 82.5 0.0 2.3 1 1 0 1 1 1 1 Fungal protein kinase F-box-like PF12937.7 KIY48241.1 - 0.0021 17.9 0.1 0.0096 15.8 0.1 2.2 1 0 0 1 1 1 1 F-box-like COX17 PF05051.13 KIY48242.1 - 5.1e-23 81.2 4.2 5.8e-23 81.0 4.2 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) ABC2_membrane PF01061.24 KIY48243.1 - 9.4e-39 133.0 14.5 9.4e-39 133.0 14.5 2.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KIY48243.1 - 3.7e-25 89.0 0.0 6.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KIY48243.1 - 0.0037 16.4 25.9 0.0037 16.4 25.9 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KIY48243.1 - 0.0057 16.6 0.2 0.014 15.3 0.2 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KIY48243.1 - 0.0061 16.4 0.2 1 9.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY48243.1 - 0.013 15.8 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KIY48243.1 - 0.035 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KIY48243.1 - 0.04 13.7 0.1 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KIY48243.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY48243.1 - 0.088 13.0 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIY48243.1 - 0.096 13.1 0.1 0.23 11.9 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIY48243.1 - 0.14 12.0 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIY48243.1 - 0.18 12.3 0.1 0.31 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIY48243.1 - 0.35 11.1 1.1 0.63 10.3 1.1 1.4 1 0 0 1 1 1 0 AAA domain DUF1270 PF06900.11 KIY48243.1 - 0.41 11.1 0.0 0.41 11.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) Egh16-like PF11327.8 KIY48244.1 - 1.3e-14 55.0 2.9 1.8e-13 51.3 0.4 2.2 1 1 1 2 2 2 2 Egh16-like virulence factor WD40 PF00400.32 KIY48247.1 - 0.00016 22.4 3.8 0.0053 17.6 0.1 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY48247.1 - 0.0002 21.6 0.0 0.00033 20.9 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIY48247.1 - 0.004 16.9 0.4 0.0085 15.9 0.4 1.5 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Phage_integrase PF00589.22 KIY48249.1 - 0.00029 20.7 0.0 0.00047 20.0 0.0 1.5 1 1 0 1 1 1 1 Phage integrase family zf-FPG_IleRS PF06827.14 KIY48249.1 - 0.086 12.7 2.1 2 8.4 0.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF2093 PF09866.9 KIY48249.1 - 0.43 10.1 2.8 0.2 11.2 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) F-box-like PF12937.7 KIY48250.1 - 0.00022 21.0 0.0 0.00098 19.0 0.0 2.2 1 1 0 1 1 1 1 F-box-like Glyoxalase_3 PF13468.6 KIY48253.1 - 9.3e-28 97.5 0.0 5.1e-27 95.1 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KIY48253.1 - 0.0042 17.3 0.0 0.86 9.9 0.0 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CDC45 PF02724.14 KIY48254.1 - 0.084 11.2 5.3 0.021 13.2 2.6 1.4 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 KIY48254.1 - 0.22 9.7 13.6 0.29 9.3 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KIY48254.1 - 0.42 10.0 15.3 0.57 9.5 15.3 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 KIY48254.1 - 0.52 9.0 2.9 0.62 8.8 2.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 KIY48254.1 - 4.5 5.7 7.3 6.5 5.2 7.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP20 PF00011.21 KIY48255.1 - 0.00078 19.6 0.0 0.0017 18.5 0.0 1.5 1 1 1 2 2 2 1 Hsp20/alpha crystallin family CBFD_NFYB_HMF PF00808.23 KIY48256.1 - 6.7e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY48256.1 - 1.7 9.0 0.0 1.7 9.0 0.0 2.4 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 V_ATPase_I PF01496.19 KIY48257.1 - 0 1056.6 0.0 0 1056.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.12 KIY48257.1 - 0.023 15.3 1.2 0.13 12.9 0.3 2.6 3 0 0 3 3 3 0 SlyX Clusterin PF01093.17 KIY48257.1 - 0.061 12.4 0.1 0.099 11.7 0.1 1.2 1 0 0 1 1 1 0 Clusterin Fungal_trans PF04082.18 KIY48258.1 - 1e-11 44.4 0.0 1.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY48258.1 - 2.3e-08 34.0 13.3 3.8e-08 33.3 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADK PF00406.22 KIY48259.1 - 2.9e-61 206.0 0.0 3.6e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIY48259.1 - 3.6e-23 82.5 0.1 9e-23 81.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KIY48259.1 - 3.5e-16 58.9 0.0 8e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KIY48259.1 - 0.00015 22.3 0.0 0.00033 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY48259.1 - 0.00025 21.2 0.0 0.00047 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Lactamase_B_2 PF12706.7 KIY48261.1 - 1e-34 119.8 0.0 2.1e-34 118.8 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIY48261.1 - 2.3e-08 34.1 0.0 8.7e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY48261.1 - 0.13 12.3 3.5 0.33 10.9 2.3 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF1077 PF06417.12 KIY48262.1 - 8.3e-47 158.0 0.1 1e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) RRM_1 PF00076.22 KIY48263.1 - 2.7e-15 55.9 0.0 0.00024 20.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY48263.1 - 0.00012 22.1 0.0 0.8 9.8 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KIY48263.1 - 0.032 14.3 0.1 40 4.4 0.0 3.3 3 0 0 3 3 3 0 Limkain b1 VCBS PF13517.6 KIY48264.1 - 3.1e-25 88.5 16.0 4.3e-08 33.6 0.0 5.6 3 3 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KIY48264.1 - 1.2e-08 34.9 9.4 0.036 14.2 0.0 6.6 7 0 0 7 7 7 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 KIY48264.1 - 2.7e-05 23.6 5.0 12 5.2 0.0 5.9 5 1 2 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region Itfg2 PF15907.5 KIY48264.1 - 0.04 13.0 0.4 0.5 9.3 0.0 2.6 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 PAC3 PF10178.9 KIY48265.1 - 0.013 15.6 0.4 0.039 14.1 0.4 1.8 1 1 0 1 1 1 0 Proteasome assembly chaperone 3 PRR20 PF15708.5 KIY48265.1 - 0.094 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Proline-rich protein family 20 PI-PLC-X PF00388.19 KIY48267.1 - 8.6e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain F-box-like PF12937.7 KIY48268.1 - 7.8e-10 38.5 0.4 3.2e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like SIMPL PF04402.14 KIY48269.1 - 0.043 14.3 0.0 0.058 13.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF541) HHH_8 PF14716.6 KIY48269.1 - 0.084 13.3 1.5 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain VSG_B PF13206.6 KIY48269.1 - 0.11 11.7 0.4 0.13 11.5 0.4 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain KDZ PF18758.1 KIY48270.1 - 4.6e-61 206.3 0.1 7.5e-61 205.6 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_M14 PF00246.24 KIY48270.1 - 0.16 11.7 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase MRC1 PF09444.10 KIY48271.1 - 0.0034 17.9 9.4 0.0047 17.4 9.4 1.1 1 0 0 1 1 1 1 MRC1-like domain DivIC PF04977.15 KIY48274.1 - 1.3 8.8 6.0 5.5 6.8 0.8 2.6 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 KIY48274.1 - 2.2 8.4 4.6 2.8 8.1 0.3 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DUF1178 PF06676.11 KIY48275.1 - 0.0028 18.1 0.5 0.0074 16.7 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) DUF4640 PF15480.6 KIY48276.1 - 0.053 13.3 0.7 0.1 12.4 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) DUF3644 PF12358.8 KIY48276.1 - 1.3 9.5 6.0 1.2 9.6 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3644) Peptidase_M50B PF13398.6 KIY48278.1 - 9.1e-52 175.6 26.1 4.9e-51 173.2 26.1 1.8 1 1 0 1 1 1 1 Peptidase M50B-like CDP-OH_P_transf PF01066.21 KIY48278.1 - 0.016 16.0 1.7 0.016 16.0 1.7 3.2 3 1 0 3 3 3 0 CDP-alcohol phosphatidyltransferase Wzy_C PF04932.15 KIY48278.1 - 2.4 7.8 18.1 2 8.1 5.6 3.0 3 0 0 3 3 3 0 O-Antigen ligase Ras PF00071.22 KIY48279.1 - 5.2e-52 175.7 0.0 6.4e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY48279.1 - 1e-34 119.3 0.1 1.3e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY48279.1 - 2.6e-12 46.5 0.0 3.2e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY48279.1 - 7.1e-07 29.3 0.1 9.6e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY48279.1 - 0.0005 20.0 0.1 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KIY48279.1 - 0.0012 18.4 0.1 0.0054 16.3 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIY48279.1 - 0.0026 18.0 0.0 0.022 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KIY48279.1 - 0.0068 15.9 0.0 0.01 15.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY48279.1 - 0.017 14.5 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KIY48279.1 - 0.017 15.5 0.0 0.023 15.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KIY48279.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.7 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KIY48279.1 - 0.029 14.9 0.1 0.043 14.3 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KIY48279.1 - 0.047 13.4 0.0 0.084 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KIY48279.1 - 0.069 12.6 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 KIY48279.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain YvfG PF09628.10 KIY48279.1 - 0.078 13.3 0.1 0.24 11.8 0.1 1.8 2 0 0 2 2 2 0 YvfG protein AAA_7 PF12775.7 KIY48279.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 KIY48279.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_21 PF13304.6 KIY48279.1 - 0.13 12.1 0.6 0.21 11.4 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KIY48279.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RTA1 PF04479.13 KIY48280.1 - 5.4e-48 163.4 11.7 9.9e-48 162.5 11.7 1.4 1 0 0 1 1 1 1 RTA1 like protein UPF0139 PF03669.13 KIY48280.1 - 0.56 10.1 2.5 1.1 9.1 0.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0139) PepSY_TM_like_2 PF16357.5 KIY48280.1 - 1.1 9.2 5.8 0.11 12.5 0.8 1.9 2 0 0 2 2 2 0 Putative PepSY_TM-like BLACT_WH PF17778.1 KIY48281.1 - 9.5e-16 57.5 0.1 1.8e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KIY48281.1 - 1.2e-13 51.6 8.2 3.7e-13 49.9 5.3 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIY48281.1 - 7.1e-05 22.4 0.2 0.00011 21.8 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIY48281.1 - 0.016 15.1 0.1 0.042 13.7 0.1 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain MA3 PF02847.17 KIY48282.1 - 2.3e-26 92.0 0.2 5.2e-26 90.9 0.2 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KIY48282.1 - 6.7e-13 48.8 4.2 8.6e-13 48.4 0.2 2.3 2 0 0 2 2 2 1 MIF4G domain RPN2_C PF18004.1 KIY48282.1 - 0.71 9.8 6.5 1 9.2 0.4 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF445 PF04286.12 KIY48282.1 - 2.1 8.0 7.1 1.3 8.8 3.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF445) Senescence PF06911.12 KIY48283.1 - 6.5e-38 130.9 0.1 9.6e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 Senescence-associated protein ATP-synt_F PF01990.17 KIY48283.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit WD40 PF00400.32 KIY48285.1 - 0.014 16.3 10.3 1.8 9.6 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Ras PF00071.22 KIY48286.1 - 2.1e-53 180.3 0.0 2.3e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY48286.1 - 2.5e-19 69.6 0.0 3.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY48286.1 - 3e-07 30.1 0.0 4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 KIY48286.1 - 0.035 14.4 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial GTP_EFTU PF00009.27 KIY48286.1 - 0.049 13.2 0.1 0.35 10.4 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 KIY48288.1 - 2e-35 120.5 0.0 3.7e-19 68.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY48288.1 - 0.029 14.0 0.0 7.6 6.2 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KIY48288.1 - 0.034 13.8 0.2 1.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_7 PF16367.5 KIY48288.1 - 0.063 13.4 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif Lactamase_B_2 PF12706.7 KIY48289.1 - 2.7e-32 111.9 0.0 5e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIY48289.1 - 9e-10 38.7 0.0 3.1e-07 30.4 0.0 3.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY48289.1 - 0.014 15.4 1.8 0.12 12.4 0.6 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Ras PF00071.22 KIY48290.1 - 5e-56 188.8 0.8 5.2e-52 175.7 0.1 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 KIY48290.1 - 4.8e-30 104.2 0.4 4.3e-26 91.5 0.1 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY48290.1 - 8.2e-09 35.1 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY48290.1 - 0.0014 18.7 0.2 0.078 13.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY48290.1 - 0.0097 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY48290.1 - 0.028 14.3 0.1 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF1128 PF06569.11 KIY48290.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) F-box PF00646.33 KIY48291.1 - 0.067 13.1 0.1 0.22 11.4 0.1 1.9 1 0 0 1 1 1 0 F-box domain Pkinase PF00069.25 KIY48292.1 - 5.8e-26 91.4 0.0 7.3e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48292.1 - 2e-11 43.7 0.0 3.3e-11 43.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY48292.1 - 2.4e-05 23.8 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF1933 PF09147.10 KIY48292.1 - 0.21 11.2 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) PIG-X PF08320.12 KIY48293.1 - 1.7e-28 100.0 0.2 1.9e-28 99.8 0.2 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 M20_dimer PF07687.14 KIY48295.1 - 4.8e-08 32.9 0.1 1.7e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KIY48295.1 - 5e-07 29.6 0.3 7.4e-07 29.1 0.3 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1905 PF08922.11 KIY48295.1 - 0.18 11.9 0.0 0.49 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) DUF484 PF04340.12 KIY48296.1 - 0.022 14.5 1.3 0.022 14.5 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF484 Fez1 PF06818.15 KIY48296.1 - 0.051 14.0 11.6 0.09 13.2 11.5 1.3 1 1 0 1 1 1 0 Fez1 CAS_C PF12026.8 KIY48296.1 - 0.33 11.0 3.7 1.1 9.3 0.2 2.1 1 1 1 2 2 2 0 Crk-Associated Substrate C-terminal domain HALZ PF02183.18 KIY48296.1 - 3 8.1 7.8 4.2 7.7 1.0 2.9 2 2 1 3 3 3 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 KIY48296.1 - 6.8 6.7 20.3 14 5.7 0.4 3.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 KIY48296.1 - 7.4 6.6 12.4 2.1 8.4 7.9 2.4 1 1 2 3 3 3 0 FlxA-like protein DUF3320 PF11784.8 KIY48297.1 - 0.7 9.9 3.1 0.64 10.0 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3320) DDOST_48kD PF03345.14 KIY48298.1 - 2.8e-122 408.6 0.0 3.2e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta CBM_21 PF03370.13 KIY48299.1 - 1.8e-24 86.1 0.0 2.1e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIY48299.1 - 1.2e-09 38.6 0.0 1.8e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) FAD_binding_3 PF01494.19 KIY48300.1 - 1.2e-73 248.4 0.0 1.6e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KIY48300.1 - 1.6e-27 96.6 0.0 2.7e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KIY48300.1 - 5.2e-05 22.1 0.0 7.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KIY48300.1 - 0.0014 17.9 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KIY48300.1 - 0.0024 16.5 0.0 0.0037 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KIY48300.1 - 0.0029 17.8 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIY48300.1 - 0.0034 16.5 0.0 0.02 14.0 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KIY48300.1 - 0.022 14.3 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KIY48300.1 - 0.042 14.4 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY48300.1 - 0.043 12.9 0.0 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KIY48302.1 - 9.3e-61 205.6 0.4 1.3e-60 205.1 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIY48302.1 - 6.9e-32 110.0 0.4 1.7e-31 108.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIY48302.1 - 1.7e-21 76.6 2.3 7.5e-17 61.7 0.2 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY48302.1 - 1e-12 48.0 2.0 1.9e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY48302.1 - 2.4e-06 27.2 0.4 4.4e-06 26.3 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY48302.1 - 3.1e-06 26.1 1.0 0.027 13.2 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KIY48302.1 - 7.3e-06 26.1 0.2 1.7e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIY48302.1 - 1.4e-05 24.4 0.0 4.5e-05 22.8 0.0 1.8 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KIY48302.1 - 0.0007 18.8 0.5 0.0013 17.9 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIY48302.1 - 0.0037 16.4 1.2 1.9 7.4 0.2 2.4 2 1 1 3 3 3 2 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KIY48302.1 - 0.0066 15.8 0.3 6.8 6.0 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KIY48302.1 - 0.052 14.1 1.3 9.3 6.9 0.1 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KIY48302.1 - 0.063 13.2 0.2 0.063 13.2 0.2 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KIY48302.1 - 0.082 12.0 0.1 0.082 12.0 0.1 2.3 2 1 1 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KIY48302.1 - 0.18 11.8 0.5 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KIY48302.1 - 7.6 6.0 9.2 0.68 9.4 1.0 2.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase Abhydrolase_1 PF00561.20 KIY48303.1 - 3.9e-19 69.3 0.3 9e-19 68.1 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY48303.1 - 5.9e-11 43.4 2.7 8.3e-11 42.9 2.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY48303.1 - 7.8e-06 25.3 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIY48303.1 - 0.089 11.5 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family EHN PF06441.12 KIY48303.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus eRF1_2 PF03464.15 KIY48305.1 - 1.6e-46 157.9 0.1 2.8e-46 157.1 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KIY48305.1 - 5.9e-38 129.8 0.3 1.2e-37 128.8 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KIY48305.1 - 5.1e-19 68.5 0.0 9.5e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KIY48305.1 - 6.4e-10 39.4 0.3 1.2e-09 38.5 0.1 1.6 2 0 0 2 2 2 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KIY48305.1 - 1.6e-09 38.2 0.0 3.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Rpp20 PF12328.8 KIY48306.1 - 1.3e-05 25.1 0.0 0.00024 21.1 0.0 2.0 1 1 1 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KIY48306.1 - 0.023 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Alba DUF748 PF05359.11 KIY48306.1 - 0.1 12.7 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) Biotin_lipoyl PF00364.22 KIY48307.1 - 1.9e-17 62.8 0.4 3.9e-17 61.8 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KIY48307.1 - 7e-07 29.5 0.0 1.8e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Lipase_GDSL_2 PF13472.6 KIY48307.1 - 0.16 12.4 0.1 0.33 11.3 0.1 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Sterol-sensing PF12349.8 KIY48308.1 - 3.1e-28 98.6 6.4 3.1e-28 98.6 6.4 2.3 1 1 1 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KIY48308.1 - 1.7e-12 46.3 0.0 2.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 KIY48308.1 - 0.56 11.2 2.7 2.6e+02 2.7 0.1 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF4064 PF13273.6 KIY48308.1 - 2.8 8.3 5.8 4.9 7.5 4.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) YwcE PF17368.2 KIY48308.1 - 7.4 7.3 9.0 17 6.1 0.0 3.4 3 0 0 3 3 3 0 Spore morphogenesis and germination YwcE Hat1_N PF10394.9 KIY48309.1 - 2e-51 174.4 0.6 4.3e-51 173.3 0.1 1.8 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KIY48309.1 - 0.00012 22.3 0.0 0.00045 20.5 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KIY48309.1 - 0.0011 19.6 0.0 0.0065 17.2 0.0 2.2 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KIY48309.1 - 0.0034 17.1 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_10 PF13673.7 KIY48309.1 - 0.037 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain COMM_domain PF07258.14 KIY48309.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 COMM domain Ribonuclease_3 PF00636.26 KIY48310.1 - 7.3e-40 135.8 0.0 1.4e-20 73.9 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIY48310.1 - 7.8e-28 97.2 0.0 6.4e-14 52.2 0.0 3.8 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KIY48310.1 - 5.2e-15 55.4 0.0 1.3e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KIY48310.1 - 2e-13 50.7 0.0 4.8e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY48310.1 - 5.2e-13 49.3 0.0 9.2e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY48310.1 - 6.9e-12 45.5 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KIY48310.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Phosducin PF02114.16 KIY48312.1 - 0.0051 15.8 0.0 0.0096 14.9 0.0 1.4 1 1 0 1 1 1 1 Phosducin adh_short PF00106.25 KIY48313.1 - 7.2e-17 61.5 0.0 8.5e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY48313.1 - 1.7e-06 27.8 0.0 5.2e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY48313.1 - 0.00081 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 KR domain E1_dh PF00676.20 KIY48314.1 - 8e-12 44.7 0.8 3.7e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Dehydrogenase E1 component Lipase_3 PF01764.25 KIY48314.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) FAD_oxidored PF12831.7 KIY48315.1 - 0.011 15.1 0.0 3 7.1 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase UPF0227 PF05728.12 KIY48315.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pyr_redox_2 PF07992.14 KIY48315.1 - 0.24 10.6 0.0 4.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase dsDNA_bind PF01984.20 KIY48317.1 - 2.6e-26 92.1 7.0 2.7e-26 92.0 7.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TetR_C_11 PF16859.5 KIY48317.1 - 0.019 15.2 3.3 0.029 14.7 3.3 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PCI PF01399.27 KIY48317.1 - 0.022 15.3 0.1 0.031 14.8 0.1 1.2 1 0 0 1 1 1 0 PCI domain NIF3 PF01784.18 KIY48318.1 - 5.5e-65 219.4 0.0 6.4e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) HET PF06985.11 KIY48319.1 - 9.7e-16 58.4 3.4 3.8e-14 53.3 0.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) YL1 PF05764.13 KIY48321.1 - 7.4 6.6 18.5 1.1 9.3 2.2 2.9 3 0 0 3 3 3 0 YL1 nuclear protein Sas10_Utp3 PF04000.15 KIY48323.1 - 3.4e-10 40.4 0.0 7.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MRG PF05712.13 KIY48324.1 - 1.7e-53 180.9 0.4 2.4e-53 180.4 0.4 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KIY48324.1 - 2.8e-11 43.1 0.6 5.4e-11 42.2 0.6 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Glyco_transf_15 PF01793.16 KIY48325.1 - 6.3e-121 403.6 9.0 8.9e-121 403.1 9.0 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Rad1 PF02144.16 KIY48327.1 - 4.4e-59 199.8 0.0 1.7e-58 197.9 0.0 1.7 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Mito_carr PF00153.27 KIY48328.1 - 4.5e-19 68.2 0.1 1.8e-05 24.6 0.0 5.0 3 1 1 4 4 4 4 Mitochondrial carrier protein TBP PF00352.21 KIY48329.1 - 5.2e-67 221.8 0.3 1.4e-32 111.5 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KIY48329.1 - 2.9e-05 24.1 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KIY48329.1 - 0.12 12.2 0.1 0.42 10.5 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) zf-C2H2_jaz PF12171.8 KIY48331.1 - 4e-06 27.0 4.3 0.0003 21.0 1.3 5.1 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-C3HC4_3 PF13920.6 KIY48331.1 - 9.5e-06 25.4 13.7 9.5e-06 25.4 13.7 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 KIY48331.1 - 0.00047 20.4 0.8 0.015 15.7 0.1 5.1 6 0 0 6 6 5 2 Zinc-finger of C2H2 type Prok-RING_4 PF14447.6 KIY48331.1 - 0.00091 19.0 14.5 0.00091 19.0 14.5 3.0 2 2 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIY48331.1 - 0.0011 18.9 16.6 0.0011 18.9 16.6 3.6 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIY48331.1 - 0.0047 16.7 16.8 0.0047 16.7 16.8 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY48331.1 - 0.0087 16.4 15.5 0.0087 16.4 15.5 3.3 2 1 1 3 3 3 1 Ring finger domain zf-RING_6 PF14835.6 KIY48331.1 - 0.015 15.2 5.1 0.015 15.2 5.1 2.3 2 1 0 2 2 1 0 zf-RING of BARD1-type protein zf-DBF PF07535.12 KIY48331.1 - 0.19 11.9 7.7 0.32 11.1 0.1 3.0 3 0 0 3 3 3 0 DBF zinc finger Rad50_zn_hook PF04423.14 KIY48331.1 - 0.2 11.5 6.9 10 6.0 1.3 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 KIY48331.1 - 3.3 8.3 0.0 3.3 8.3 0.0 6.3 5 1 1 6 6 6 0 Zinc finger, C2H2 type NTF2 PF02136.20 KIY48332.1 - 2.2e-31 108.9 0.1 2.5e-31 108.8 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Lysine_decarbox PF03641.14 KIY48334.1 - 8.6e-33 113.2 0.0 1.3e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KIY48334.1 - 1.2e-06 28.2 2.5 1.9e-06 27.6 2.5 1.3 1 0 0 1 1 1 1 SLOG cluster4 family zinc_ribbon_10 PF10058.9 KIY48335.1 - 4.5e-18 64.7 0.2 7.7e-18 64.0 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Cut12 PF11500.8 KIY48335.1 - 0.032 14.2 0.3 0.052 13.5 0.3 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein tRNA_anti-like PF12869.7 KIY48335.1 - 0.037 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like PhnA_Zn_Ribbon PF08274.12 KIY48335.1 - 0.05 13.6 2.2 0.14 12.1 2.2 1.6 1 1 1 2 2 2 0 PhnA Zinc-Ribbon Dynamin_M PF01031.20 KIY48336.1 - 3.5e-102 341.5 0.0 6.1e-102 340.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIY48336.1 - 1.3e-54 184.8 0.0 2.1e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIY48336.1 - 1.2e-25 89.4 4.6 1.2e-25 89.4 4.6 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY48336.1 - 0.00028 20.9 0.0 0.0012 18.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY48336.1 - 0.047 14.1 0.0 0.99 9.8 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain tRNA-synt_1b PF00579.25 KIY48337.1 - 7.3e-19 68.2 0.0 3e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) RNase_P_pop3 PF08228.11 KIY48338.1 - 4.6e-14 52.8 0.2 1.3e-09 38.3 0.0 2.5 2 1 0 2 2 2 2 RNase P subunit Pop3 MUG113 PF13455.6 KIY48339.1 - 1.9e-16 60.5 0.0 6.1e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIY48339.1 - 3.6e-11 43.5 0.1 4.4e-10 40.0 0.0 2.3 2 1 0 2 2 2 1 T5orf172 domain Sas10_Utp3 PF04000.15 KIY48340.1 - 2.1e-08 34.7 0.1 4.6e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Titin_Ig-rpts PF06582.12 KIY48340.1 - 0.026 14.5 0.2 0.058 13.3 0.2 1.6 1 0 0 1 1 1 0 Titin repeat DUF1644 PF07800.12 KIY48340.1 - 0.13 12.4 0.3 0.22 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) CDH-cyt PF16010.5 KIY48341.1 - 2.4e-54 183.8 0.3 2.4e-54 183.8 0.3 3.2 3 1 0 3 3 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KIY48341.1 - 1.8e-25 89.9 0.0 1.6e-24 86.8 0.0 2.5 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY48341.1 - 2e-22 80.2 0.5 5.8e-22 78.8 0.5 1.8 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIY48341.1 - 4.3e-09 36.0 0.0 4.3e-09 36.0 0.0 2.1 2 1 0 2 2 1 1 FAD binding domain DAO PF01266.24 KIY48341.1 - 4.1e-07 29.9 0.1 3.1e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY48341.1 - 1e-05 24.5 0.3 4.6e-05 22.3 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KIY48341.1 - 1.6e-05 24.3 0.1 3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIY48341.1 - 1.8e-05 24.3 0.2 0.00045 19.7 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY48341.1 - 6.5e-05 22.3 0.0 0.00043 19.6 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY48341.1 - 0.00011 21.6 0.0 0.00029 20.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY48341.1 - 0.00038 20.6 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIY48341.1 - 0.00043 19.4 0.1 0.00043 19.4 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KIY48341.1 - 0.0078 15.5 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KIY48341.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIY48341.1 - 0.063 13.8 0.9 0.23 12.0 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KIY48341.1 - 1.6 9.0 4.2 0.54 10.5 0.2 2.3 3 0 0 3 3 3 0 TrkA-N domain Aspzincin_M35 PF14521.6 KIY48342.1 - 1.6e-13 51.4 0.2 2.6e-13 50.7 0.2 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KIY48342.1 - 3.9e-10 39.1 9.4 6.1e-10 38.5 9.4 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 KIY48342.1 - 8.8e-09 35.3 0.6 1.9e-08 34.2 0.6 1.6 1 1 0 1 1 1 1 Putative peptidase family A2M PF00207.22 KIY48342.1 - 0.086 12.7 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Alpha-2-macroglobulin family dCMP_cyt_deam_1 PF00383.23 KIY48343.1 - 1.8e-24 85.5 0.9 2.5e-24 85.1 0.9 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIY48343.1 - 2.1e-11 43.7 0.1 3.1e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC4_like PF18774.1 KIY48343.1 - 0.035 14.0 0.3 0.08 12.9 0.3 1.6 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase AAA_18 PF13238.6 KIY48343.1 - 0.053 14.1 0.2 11 6.6 0.0 3.2 2 2 1 3 3 3 0 AAA domain SNAD4 PF18750.1 KIY48343.1 - 0.061 13.4 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KIY48343.1 - 0.45 10.6 4.3 2.3 8.3 4.3 2.2 1 1 0 1 1 1 0 Bd3614-like deaminase MMS19_N PF14500.6 KIY48344.1 - 0.018 14.6 3.8 0.051 13.2 0.0 3.2 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 KIY48344.1 - 0.02 15.1 0.1 0.63 10.5 0.0 3.5 2 0 0 2 2 2 0 HEAT repeat NTP_transf_4 PF13562.6 KIY48344.1 - 0.064 13.5 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Chorismate_bind PF00425.18 KIY48345.1 - 1.3e-68 231.4 0.0 1.7e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KIY48345.1 - 4e-32 111.5 0.0 6.3e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KIY48345.1 - 1.2e-12 48.2 0.0 5.2e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KIY48345.1 - 2.5e-06 27.4 0.3 1.5e-05 24.8 0.3 2.0 1 1 0 1 1 1 1 Peptidase C26 HRXXH PF13933.6 KIY48346.1 - 3.6e-13 49.7 0.9 6.7e-13 48.8 0.1 1.7 2 0 0 2 2 2 1 Putative peptidase family Peptidase_M35 PF02102.15 KIY48346.1 - 6.5e-10 38.4 12.1 1.1e-09 37.6 12.1 1.4 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KIY48346.1 - 3.3e-09 37.5 0.0 8e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase A2M PF00207.22 KIY48346.1 - 0.041 13.7 0.1 0.43 10.5 0.0 2.4 3 0 0 3 3 3 0 Alpha-2-macroglobulin family Aminotran_1_2 PF00155.21 KIY48348.1 - 8.3e-37 127.2 0.0 1e-36 126.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIY48348.1 - 0.062 11.8 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KIY48348.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pkinase PF00069.25 KIY48349.1 - 4.6e-64 216.3 0.0 5.4e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48349.1 - 8.3e-32 110.5 0.0 1.8e-31 109.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY48349.1 - 0.00061 19.2 0.2 0.0011 18.3 0.2 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KIY48349.1 - 0.0088 15.7 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KIY48349.1 - 0.016 14.2 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIY48349.1 - 0.082 11.7 0.1 0.13 11.0 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase Ribosomal_L37 PF08561.10 KIY48350.1 - 1.1e-16 61.4 4.8 2e-14 54.1 0.2 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 zf-RING_4 PF14570.6 KIY48351.1 - 7e-17 61.0 6.8 1.1e-16 60.3 6.8 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KIY48351.1 - 0.0037 17.1 6.2 0.0067 16.3 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KIY48351.1 - 0.0068 16.2 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 KIY48351.1 - 0.025 14.4 5.2 0.055 13.3 5.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 KIY48351.1 - 0.1 12.7 2.3 0.21 11.7 2.3 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 KIY48351.1 - 0.49 10.3 3.1 0.96 9.4 3.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) UDG PF03167.19 KIY48352.1 - 5.9e-19 68.6 0.0 8e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily YIF1 PF03878.15 KIY48353.1 - 1.4e-63 214.7 0.1 1.7e-63 214.4 0.1 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KIY48353.1 - 0.03 14.0 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain ArAE_2_N PF10337.9 KIY48354.1 - 2e-45 155.7 6.4 3.4e-45 155.0 2.9 2.3 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KIY48354.1 - 1.1e-26 94.2 0.0 3.7e-26 92.4 0.0 2.0 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KIY48354.1 - 2.2e-07 31.0 16.4 2.2e-07 31.0 16.4 3.4 3 1 0 3 3 3 1 Fusaric acid resistance protein-like SH3-WW_linker PF16618.5 KIY48354.1 - 0.025 15.0 3.8 0.046 14.2 3.8 1.3 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 RTA1 PF04479.13 KIY48355.1 - 1.4e-07 31.3 12.9 1.4e-07 31.3 12.9 2.3 1 1 1 2 2 2 1 RTA1 like protein Trs65 PF12735.7 KIY48360.1 - 0.046 13.1 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Peptidase_S48 PF03574.15 KIY48360.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S48 Methyltransf_16 PF10294.9 KIY48361.1 - 2.6e-12 46.8 0.0 3.3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIY48361.1 - 0.0019 18.0 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY48361.1 - 0.0056 17.4 0.0 0.011 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF1295 PF06966.12 KIY48362.1 - 3.6e-20 72.5 0.1 4.6e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KIY48362.1 - 3.5e-09 37.0 0.0 9.5e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 KIY48362.1 - 2.7e-08 33.6 0.8 3.9e-08 33.0 0.8 1.3 1 0 0 1 1 1 1 NnrU protein ICMT PF04140.14 KIY48362.1 - 1.5e-06 28.5 0.0 3.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KIY48362.1 - 3.7e-06 27.0 0.0 7.3e-06 26.0 0.0 1.6 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 KIY48362.1 - 2.4e-05 23.3 0.1 8e-05 21.6 0.1 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Microtub_bd PF16796.5 KIY48363.1 - 0.014 15.4 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Microtubule binding Kinesin PF00225.23 KIY48363.1 - 0.028 13.4 0.0 0.033 13.1 0.0 1.0 1 0 0 1 1 1 0 Kinesin motor domain ATP-synt_A PF00119.20 KIY48365.1 - 7.1e-10 39.2 11.0 7.7e-10 39.1 11.0 1.0 1 0 0 1 1 1 1 ATP synthase A chain F-box-like PF12937.7 KIY48370.1 - 3.4e-08 33.3 0.4 7.4e-08 32.2 0.4 1.6 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 KIY48372.1 - 1.3e-73 247.6 0.2 1.3e-73 247.6 0.2 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48372.1 - 2.5e-52 177.7 1.5 3.5e-52 177.3 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KIY48372.1 - 2.7e-22 78.9 0.0 6.6e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KIY48372.1 - 2.1e-06 27.3 0.0 3.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY48372.1 - 6.2e-06 25.2 1.4 1.4e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KIY48372.1 - 7.1e-05 21.9 1.5 0.00012 21.2 1.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY48372.1 - 0.0004 20.4 2.7 0.022 14.7 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family PH PF00169.29 KIY48372.1 - 0.002 18.6 0.1 0.0059 17.1 0.1 1.8 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.11 KIY48372.1 - 0.027 13.5 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KIY48372.1 - 0.04 13.3 0.3 0.16 11.3 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S13 PF00416.22 KIY48372.1 - 0.056 13.8 0.5 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Dimer_Tnp_hAT PF05699.14 KIY48373.1 - 2.2e-18 65.8 0.4 2.6e-18 65.6 0.4 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIY48374.1 - 2.3e-05 24.7 0.1 3.1e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Methyltransf_10 PF05971.12 KIY48374.1 - 0.048 13.0 0.1 0.056 12.8 0.1 1.1 1 0 0 1 1 1 0 RNA methyltransferase RasGEF PF00617.19 KIY48374.1 - 0.069 13.3 0.1 0.075 13.2 0.1 1.1 1 0 0 1 1 1 0 RasGEF domain DDE_Tnp_4 PF13359.6 KIY48375.1 - 3.4e-18 65.8 0.0 4.6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4515 PF14988.6 KIY48376.1 - 0.0049 16.7 2.0 0.0082 16.0 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) Cnn_1N PF07989.11 KIY48376.1 - 0.017 15.2 1.3 0.043 14.0 1.3 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 KIY48376.1 - 0.022 14.1 2.6 0.041 13.2 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DMPK_coil PF08826.10 KIY48376.1 - 0.045 13.9 5.1 0.088 12.9 5.1 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF5595 PF18077.1 KIY48376.1 - 0.071 13.2 0.9 0.15 12.2 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DUF4763 PF15960.5 KIY48376.1 - 0.073 12.4 4.4 0.14 11.5 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Rx_N PF18052.1 KIY48376.1 - 0.17 12.2 1.7 0.44 10.8 1.7 1.7 1 0 0 1 1 1 0 Rx N-terminal domain Spc24 PF08286.11 KIY48376.1 - 0.2 11.9 1.1 0.27 11.5 0.1 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KIY48376.1 - 0.35 11.0 4.3 1 9.5 4.3 1.8 1 0 0 1 1 1 0 Basic region leucine zipper APG6_N PF17675.1 KIY48376.1 - 0.48 11.0 7.1 0.13 12.8 2.4 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region LapA_dom PF06305.11 KIY48376.1 - 1.7 8.5 8.2 2.6 7.9 1.8 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ribosomal_S27 PF01599.19 KIY48377.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.9 3 0 0 3 3 3 0 Ribosomal protein S27a ADH_N PF08240.12 KIY48378.1 - 0.00061 19.6 0.0 0.00076 19.3 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tetraspanin PF00335.20 KIY48379.1 - 2.3e-05 24.2 2.8 7.3e-05 22.6 3.4 1.6 1 1 1 2 2 2 1 Tetraspanin family DUF2070 PF09843.9 KIY48379.1 - 0.28 9.4 1.3 0.31 9.3 1.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4064 PF13273.6 KIY48379.1 - 2 8.8 5.2 4 7.8 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Dymeclin PF09742.9 KIY48380.1 - 0.004 15.6 0.3 0.0061 15.0 0.3 1.3 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein AAA_16 PF13191.6 KIY48380.1 - 0.032 14.6 0.3 0.22 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA-ATPase_like PF09820.9 KIY48381.1 - 1.5e-12 47.5 0.0 2.9e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Predicted AAA-ATPase AAA_16 PF13191.6 KIY48381.1 - 0.059 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Seryl_tRNA_N PF02403.22 KIY48385.1 - 0.069 13.4 0.6 0.14 12.4 0.1 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.32 KIY48388.1 - 6.4e-06 26.8 1.0 0.0033 18.2 0.0 3.1 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY48388.1 - 0.0021 18.3 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIY48388.1 - 0.0071 16.1 0.8 0.011 15.5 0.8 1.4 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Peptidase_M74 PF03411.13 KIY48388.1 - 0.12 11.9 0.2 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase PGI PF00342.19 KIY48390.1 - 4.1e-229 761.1 0.0 4.6e-229 761.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Rox3 PF08633.10 KIY48391.1 - 0.0032 17.8 10.4 0.13 12.5 0.6 2.7 3 0 0 3 3 3 2 Rox3 mediator complex subunit Fez1 PF06818.15 KIY48392.1 - 0.0048 17.4 0.0 0.0072 16.8 0.0 1.2 1 0 0 1 1 1 1 Fez1 DUF4298 PF14131.6 KIY48392.1 - 0.023 14.7 0.0 0.95 9.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) CpxA_peri PF16527.5 KIY48392.1 - 0.092 13.1 0.0 0.2 12.1 0.0 1.5 1 1 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain FliJ PF02050.16 KIY48392.1 - 0.14 12.4 0.0 0.35 11.1 0.1 1.5 2 0 0 2 2 2 0 Flagellar FliJ protein DUF3552 PF12072.8 KIY48393.1 - 0.00075 19.0 10.1 0.00075 19.0 10.1 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3552) Apidaecin PF00807.17 KIY48393.1 - 0.041 14.0 6.7 0.18 11.9 6.7 2.2 1 0 0 1 1 1 0 Apidaecin CBP_BcsR PF10945.8 KIY48393.1 - 1.7 8.2 5.6 2.1 7.9 0.1 2.9 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR DUF1184 PF06683.11 KIY48394.1 - 0.66 9.4 4.4 0.43 10.1 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1184) Glyco_trans_1_2 PF13524.6 KIY48394.1 - 5.5 7.5 7.3 0.58 10.6 0.2 2.9 3 0 0 3 3 3 0 Glycosyl transferases group 1 Citrate_bind PF16114.5 KIY48395.1 - 5.9e-88 293.0 0.4 1.2e-87 292.0 0.2 1.7 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KIY48395.1 - 6e-19 68.3 0.2 8.4e-16 58.0 0.1 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KIY48395.1 - 8.5e-18 64.6 0.0 5.3e-17 62.0 0.0 2.3 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.19 KIY48395.1 - 8.1e-14 52.1 0.0 2.3e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KIY48395.1 - 4.2e-08 33.0 0.0 8.4e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KIY48395.1 - 0.00014 21.6 0.0 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DLH PF01738.18 KIY48396.1 - 1.1e-21 77.4 0.0 1.3e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2002 PF09400.10 KIY48396.1 - 0.1 12.6 0.0 2.5 8.2 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2002) Endothelin PF00322.17 KIY48397.1 - 0.71 9.5 3.5 0.46 10.1 1.0 2.0 2 0 0 2 2 2 0 Endothelin family BTB PF00651.31 KIY48398.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain CBM_20 PF00686.19 KIY48400.1 - 1.9e-10 40.5 0.0 2.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain SH3_1 PF00018.28 KIY48401.1 - 1.6e-16 59.6 3.2 2.1e-07 30.4 0.2 2.1 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KIY48401.1 - 2e-14 53.2 4.9 1.7e-06 27.8 0.4 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KIY48401.1 - 7.5e-05 22.3 0.3 0.42 10.3 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain TrkA_C PF02080.21 KIY48401.1 - 0.039 13.8 0.1 12 5.9 0.0 2.2 2 0 0 2 2 2 0 TrkA-C domain Zds_C PF08632.10 KIY48401.1 - 0.049 13.4 0.1 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Peptidase_A4 PF01828.17 KIY48401.1 - 0.049 13.1 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase A4 family DUF4443 PF14544.6 KIY48401.1 - 0.076 13.2 0.0 11 6.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4443) F-box-like PF12937.7 KIY48402.1 - 0.074 13.0 1.3 1 9.3 0.1 3.0 2 1 0 2 2 2 0 F-box-like Na_trans_assoc PF06512.13 KIY48402.1 - 0.17 12.1 1.6 5.8 7.1 0.5 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated FA_desaturase PF00487.24 KIY48405.1 - 7.1e-15 55.5 26.5 1.3e-14 54.7 26.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIY48405.1 - 3.2e-12 46.4 0.0 6.7e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RdRP PF05183.12 KIY48407.1 - 6.7e-110 368.4 0.0 9.6e-110 367.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase ADH_N PF08240.12 KIY48408.1 - 5.1e-29 100.3 1.5 1.1e-28 99.3 1.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY48408.1 - 2e-27 95.7 0.4 3.3e-27 95.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY48408.1 - 0.0085 17.1 0.0 0.013 16.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TOBE_2 PF08402.10 KIY48408.1 - 0.071 13.3 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 TOBE domain 2-Hacid_dh_C PF02826.19 KIY48409.1 - 3.1e-42 144.0 0.3 8.8e-41 139.2 0.3 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KIY48409.1 - 0.00098 19.1 0.1 8.8 6.3 0.1 3.3 3 0 0 3 3 3 2 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIY48409.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KIY48409.1 - 0.0027 17.8 0.0 0.57 10.2 0.1 2.3 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 KIY48409.1 - 0.0057 17.2 0.1 0.031 14.9 0.2 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KIY48409.1 - 0.0075 15.9 0.1 0.013 15.1 0.1 1.5 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 KIY48409.1 - 0.04 13.6 0.3 0.066 12.9 0.3 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_2 PF03446.15 KIY48409.1 - 0.046 13.9 0.0 0.098 12.8 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 KIY48409.1 - 0.12 11.7 0.1 0.38 10.1 0.3 1.7 2 0 0 2 2 2 0 ThiF family PCI PF01399.27 KIY48410.1 - 1e-07 32.4 0.0 2.2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain 2-Hacid_dh_C PF02826.19 KIY48411.1 - 1.1e-42 145.4 0.1 1.1e-30 106.3 0.0 2.0 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KIY48411.1 - 7.2e-05 23.3 0.7 0.017 15.7 0.1 3.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KIY48411.1 - 0.0035 17.4 0.1 1.3 9.1 0.1 2.3 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY48411.1 - 0.019 14.3 0.0 0.056 12.7 0.0 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KIY48411.1 - 0.02 14.3 0.1 0.16 11.3 0.2 2.0 2 0 0 2 2 2 0 ThiF family NAD_binding_2 PF03446.15 KIY48411.1 - 0.033 14.4 0.0 0.067 13.4 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIY48411.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 KIY48411.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_2 PF00891.18 KIY48412.1 - 4e-13 49.2 0.0 1.6e-11 43.9 0.0 2.0 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_12 PF08242.12 KIY48412.1 - 0.0024 18.6 0.0 0.0037 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY48412.1 - 0.0031 17.4 0.0 0.0049 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY48412.1 - 0.0031 17.1 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain AdoMet_MTase PF07757.13 KIY48414.1 - 1.6e-33 115.4 0.0 2.6e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KIY48414.1 - 0.016 15.2 0.1 0.04 13.9 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIY48414.1 - 0.18 11.6 0.2 0.35 10.7 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain Adeno_E3_CR2 PF02439.15 KIY48416.1 - 0.0016 18.1 0.6 0.0037 17.0 0.6 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.12 KIY48416.1 - 0.021 14.6 0.5 0.041 13.7 0.5 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 KIY48416.1 - 0.023 14.1 1.7 0.066 12.6 1.7 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 KIY48416.1 - 0.041 12.7 0.1 0.08 11.8 0.0 1.5 2 0 0 2 2 2 0 Amnionless EphA2_TM PF14575.6 KIY48416.1 - 0.064 14.1 0.0 0.23 12.4 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KIY48416.1 - 0.09 12.7 0.1 0.09 12.7 0.1 2.1 3 0 0 3 3 3 0 TMEM154 protein family Syndecan PF01034.20 KIY48416.1 - 0.32 10.9 1.5 0.83 9.6 1.3 1.7 2 0 0 2 2 2 0 Syndecan domain RhlB PF12300.8 KIY48416.1 - 0.46 10.6 8.4 1 9.5 8.4 1.5 1 1 0 1 1 1 0 ATP-dependent RNA helicase RhlB Glycophorin_A PF01102.18 KIY48416.1 - 1.2 9.4 6.0 0.18 12.0 0.6 2.5 2 2 0 2 2 2 0 Glycophorin A G-alpha PF00503.20 KIY48417.1 - 5.6e-92 308.6 0.1 7e-92 308.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY48417.1 - 7.1e-05 22.3 0.1 0.00024 20.6 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KIY48417.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein F-box PF00646.33 KIY48418.1 - 0.00018 21.3 0.0 0.0009 19.1 0.0 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KIY48418.1 - 0.018 15.4 0.0 2.1 8.9 0.1 3.5 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) PRANC PF09372.10 KIY48418.1 - 0.051 13.9 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 0 PRANC domain LRR_1 PF00560.33 KIY48418.1 - 2.9 8.8 6.4 59 4.8 0.0 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat CH PF00307.31 KIY48420.1 - 1.3e-73 244.1 0.0 1.7e-18 66.8 0.0 4.7 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KIY48420.1 - 0.0013 18.5 0.0 8.6 6.3 0.0 4.3 5 0 0 5 5 5 2 CAMSAP CH domain Mito_carr PF00153.27 KIY48423.1 - 1.8e-57 191.2 1.4 1.3e-21 76.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LapA_dom PF06305.11 KIY48423.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_16 PF00722.21 KIY48424.1 - 0.0075 15.8 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CH PF00307.31 KIY48427.1 - 3.2e-28 98.1 0.0 9.9e-13 48.2 0.0 3.6 3 1 0 3 3 3 3 Calponin homology (CH) domain EF-hand_13 PF17958.1 KIY48427.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Glycos_transf_2 PF00535.26 KIY48428.1 - 0.19 11.5 0.2 0.54 10.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Bestrophin PF01062.21 KIY48429.1 - 1.9e-31 109.6 2.7 1.8e-15 57.1 0.0 2.8 3 0 0 3 3 3 2 Bestrophin, RFP-TM, chloride channel CBS PF00571.28 KIY48430.1 - 1.3e-10 41.5 0.0 0.00032 21.1 0.0 2.7 2 1 1 3 3 3 2 CBS domain Sulfotransfer_3 PF13469.6 KIY48431.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family RPN1_RPN2_N PF17781.1 KIY48432.1 - 2.6e-115 385.1 0.0 4e-115 384.5 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KIY48432.1 - 2.6e-30 104.2 0.1 5.1e-30 103.3 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KIY48432.1 - 1.8e-23 81.7 22.4 8.9e-06 25.9 0.1 9.0 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KIY48432.1 - 1.8e-05 25.0 2.7 0.72 10.3 0.0 4.8 5 1 0 5 5 5 2 HEAT repeats DUF1039 PF06287.11 KIY48432.1 - 0.015 15.7 0.2 0.66 10.4 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1039) Ribosomal_S6e PF01092.19 KIY48433.1 - 4.5e-58 194.7 1.5 2e-57 192.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S6e Biotin_carb_C PF02785.19 KIY48433.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.6 2 0 0 2 2 2 0 Biotin carboxylase C-terminal domain Cyclin_N PF00134.23 KIY48434.1 - 7e-44 148.6 1.6 1.3e-43 147.8 1.6 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY48434.1 - 1.2e-23 83.5 0.0 2.8e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain adh_short PF00106.25 KIY48435.1 - 1.9e-30 105.8 0.0 1.9e-26 92.7 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY48435.1 - 5.5e-18 65.4 0.0 2.3e-16 60.1 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY48435.1 - 8.9e-10 38.8 0.1 1.5e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY48435.1 - 2.2e-05 24.0 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIY48435.1 - 0.0014 18.9 0.2 0.0023 18.2 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KIY48435.1 - 0.0044 16.5 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KIY48435.1 - 0.015 15.4 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_PK PF05891.12 KIY48435.1 - 0.016 14.8 0.5 0.19 11.2 0.5 2.1 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Polysacc_synt_2 PF02719.15 KIY48435.1 - 0.031 13.4 0.2 0.062 12.4 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TIR-like PF10137.9 KIY48435.1 - 0.037 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Amnionless PF14828.6 KIY48438.1 - 0.016 14.0 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 KIY48438.1 - 0.018 14.9 0.5 0.034 14.1 0.5 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KIY48438.1 - 0.42 10.1 4.7 1 8.8 4.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain COesterase PF00135.28 KIY48439.1 - 3.1e-77 260.6 0.0 9.3e-46 156.7 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY48439.1 - 1e-05 25.5 0.0 0.00028 20.8 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold PALP PF00291.25 KIY48439.1 - 0.007 15.8 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2034 PF10356.9 KIY48440.1 - 1.8e-17 63.3 0.2 1.2e-12 47.6 0.8 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KIY48440.1 - 8.3e-05 22.6 0.0 0.00023 21.2 0.0 1.7 2 0 0 2 2 2 1 Restriction endonuclease Ribosomal_S18 PF01084.20 KIY48441.1 - 2.1e-14 53.5 1.4 3.9e-14 52.6 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Glyco_hydro_79C PF16862.5 KIY48442.1 - 1.4e-19 70.8 0.3 4.9e-19 69.1 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain adh_short PF00106.25 KIY48443.1 - 9.4e-22 77.4 0.0 4.5e-15 55.6 0.1 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KIY48443.1 - 1e-08 35.0 0.1 2.6e-07 30.4 0.1 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY48443.1 - 7.6e-07 29.2 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KIY48443.1 - 0.054 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIY48443.1 - 0.08 12.8 1.0 0.27 11.1 0.2 2.0 2 0 0 2 2 2 0 NAD(P)H-binding Epimerase PF01370.21 KIY48443.1 - 0.12 11.8 0.0 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DDE_Tnp_Tn3 PF01526.17 KIY48443.1 - 0.15 10.8 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain RRF PF01765.19 KIY48444.1 - 9e-25 87.5 0.2 1.3e-24 87.0 0.2 1.2 1 0 0 1 1 1 1 Ribosome recycling factor VPR PF00522.18 KIY48444.1 - 0.14 12.2 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 VPR/VPX protein MFS_1 PF07690.16 KIY48446.1 - 4e-45 154.3 47.0 1.8e-44 152.1 47.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY48446.1 - 8.9e-16 57.8 10.0 8.9e-16 57.8 10.0 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KIY48446.1 - 2e-09 36.4 11.1 2e-09 36.4 11.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KIY48446.1 - 9.7e-07 28.0 2.8 0.00019 20.4 5.0 2.7 1 1 1 2 2 2 1 MFS_1 like family MukB PF04310.12 KIY48446.1 - 2.8 7.7 5.0 4.4 7.1 0.3 2.5 3 0 0 3 3 3 0 MukB N-terminal F-box-like PF12937.7 KIY48448.1 - 1.5e-07 31.2 0.5 5.9e-07 29.3 0.5 2.2 1 1 0 1 1 1 1 F-box-like CPSF73-100_C PF11718.8 KIY48449.1 - 1.4e-51 175.2 0.0 2.1e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KIY48449.1 - 7e-28 97.1 0.0 2.5e-27 95.4 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KIY48449.1 - 9.5e-19 67.6 0.0 2.3e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY48449.1 - 1e-14 55.0 1.2 1.7e-13 51.0 1.1 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KIY48449.1 - 1.4e-13 50.5 0.1 2.9e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KIY48449.1 - 9.8e-08 31.7 1.6 6.1e-07 29.2 0.3 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIY48449.1 - 1.1e-06 28.6 2.1 3.1e-06 27.2 0.1 2.7 3 1 0 3 3 3 1 Beta-lactamase superfamily domain baeRF_family2 PF18844.1 KIY48449.1 - 0.086 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 2OG-FeII_Oxy PF03171.20 KIY48450.1 - 5.9e-23 81.3 0.0 9.4e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KIY48450.1 - 2.3e-15 57.4 0.1 8.1e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal COesterase PF00135.28 KIY48451.1 - 2e-103 347.0 0.0 3.1e-103 346.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY48451.1 - 4.4e-06 26.7 0.1 0.00033 20.6 0.1 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY48452.1 - 6.2e-98 328.9 1.4 2.4e-97 327.0 1.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY48452.1 - 1.2e-05 25.2 0.6 0.0003 20.7 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIY48452.1 - 0.086 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1275 PF06912.11 KIY48453.1 - 7.3e-31 107.6 17.1 8.7e-31 107.3 17.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Ammonium_transp PF00909.21 KIY48454.1 - 1.1e-114 383.2 28.9 1.3e-114 383.0 28.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Peptidase_C14 PF00656.22 KIY48455.1 - 5.9e-34 118.1 0.0 7.3e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KIY48455.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 KIY48456.1 - 2.4e-13 50.6 0.0 5.7e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 Caspase domain AgrB PF04647.15 KIY48457.1 - 0.073 12.4 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Accessory gene regulator B Zip PF02535.22 KIY48457.1 - 2.3 7.4 11.2 4 6.6 11.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ECH_1 PF00378.20 KIY48459.1 - 1.5e-53 181.7 0.0 1.7e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY48459.1 - 2e-30 106.4 0.1 3.6e-27 95.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Melibiase_2 PF16499.5 KIY48460.1 - 2.7e-47 161.3 7.8 1e-37 129.9 4.5 3.0 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KIY48460.1 - 2.6e-15 56.2 0.2 1.3e-14 54.0 0.1 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIY48460.1 - 0.0051 15.8 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Melibiase Fungal_trans PF04082.18 KIY48461.1 - 1.9e-22 79.6 0.0 3.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY48461.1 - 4.6e-10 39.5 10.6 8.7e-10 38.6 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.28 KIY48462.1 - 3.7e-19 68.6 0.0 5.7e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MOR2-PAG1_N PF14222.6 KIY48463.1 - 9.6e-143 477.0 0.0 2.3e-142 475.8 0.0 1.7 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KIY48463.1 - 2.4e-82 276.6 4.4 2.1e-81 273.5 2.1 3.2 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KIY48463.1 - 5.2e-12 44.3 0.5 5.6e-11 40.9 0.0 2.3 2 0 0 2 2 2 1 Cell morphogenesis central region Mlh1_C PF16413.5 KIY48464.1 - 1e-86 290.7 0.2 2e-86 289.7 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KIY48464.1 - 4.4e-26 90.9 0.0 9.5e-26 89.8 0.0 1.6 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KIY48464.1 - 3.8e-13 49.5 0.0 1.5e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIY48464.1 - 5.7e-08 33.3 0.0 1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tri3 PF07428.11 KIY48465.1 - 0.11 11.3 0.0 13 4.5 0.0 2.3 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 ABC2_membrane PF01061.24 KIY48466.1 - 4.1e-70 235.5 47.4 1.4e-37 129.1 16.6 2.6 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.12 KIY48466.1 - 3.4e-35 119.8 1.9 1.5e-28 98.5 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KIY48466.1 - 7.7e-26 91.2 0.0 2.6e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KIY48466.1 - 1.6e-12 47.8 0.1 3.9e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIY48466.1 - 1.3e-07 32.1 0.1 0.00048 20.6 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY48466.1 - 2e-07 31.1 0.2 2.4e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIY48466.1 - 8.5e-06 26.1 0.0 0.016 15.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KIY48466.1 - 4.4e-05 23.5 0.0 0.079 13.0 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIY48466.1 - 0.00076 19.2 0.5 0.023 14.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KIY48466.1 - 0.0017 18.0 0.1 0.043 13.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY48466.1 - 0.0021 18.2 0.0 0.76 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY48466.1 - 0.0025 17.8 0.2 0.22 11.4 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 KIY48466.1 - 0.0028 17.9 0.2 0.17 12.1 0.2 2.4 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 KIY48466.1 - 0.0043 16.9 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase TsaE PF02367.17 KIY48466.1 - 0.0074 16.3 0.3 0.2 11.6 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 KIY48466.1 - 0.0089 15.9 0.1 2 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KIY48466.1 - 0.012 15.2 0.9 0.27 10.8 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KIY48466.1 - 0.012 16.1 0.1 0.026 15.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIY48466.1 - 0.016 14.6 0.0 0.96 8.8 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KIY48466.1 - 0.018 15.5 0.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIY48466.1 - 0.024 14.4 0.8 0.55 9.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIY48466.1 - 0.073 13.5 0.3 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KIY48466.1 - 0.078 13.4 0.0 15 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIY48466.1 - 0.098 12.4 0.2 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIY48466.1 - 0.15 12.3 0.1 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KIY48466.1 - 0.18 11.3 0.1 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 KIY48466.1 - 0.19 11.0 0.0 1.9 7.7 0.0 2.1 2 0 0 2 2 2 0 Septin ABC_ATPase PF09818.9 KIY48466.1 - 0.25 10.1 0.1 0.43 9.3 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MBOAT_2 PF13813.6 KIY48467.1 - 1.8e-22 79.4 2.2 4.4e-22 78.2 2.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family TLD PF07534.16 KIY48468.1 - 8e-28 97.4 0.0 9.2e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 TLD PfkB PF00294.24 KIY48469.1 - 8.7e-05 22.0 0.0 0.07 12.4 0.0 3.0 3 0 0 3 3 3 3 pfkB family carbohydrate kinase OmpH PF03938.14 KIY48471.1 - 0.18 12.1 6.9 0.25 11.7 6.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GvpL_GvpF PF06386.11 KIY48471.1 - 0.19 11.6 3.1 0.22 11.4 3.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF1451 PF07295.11 KIY48471.1 - 0.32 11.0 5.0 0.66 10.0 4.8 1.5 1 1 0 1 1 1 0 Zinc-ribbon containing domain WEMBL PF05701.11 KIY48473.1 - 0.012 14.3 1.9 0.015 14.1 1.9 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DHR10 PF18595.1 KIY48473.1 - 0.022 14.8 1.1 0.038 14.0 1.1 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Ntox1 PF15500.6 KIY48474.1 - 1.5 9.2 5.6 48 4.4 0.0 3.8 3 0 0 3 3 3 0 Putative RNase-like toxin, toxin_1 TPR_MLP1_2 PF07926.12 KIY48474.1 - 2.6 8.1 17.2 0.55 10.3 8.5 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HRI1 PF16815.5 KIY48475.1 - 8.4e-30 104.2 0.1 1e-29 103.9 0.1 1.1 1 0 0 1 1 1 1 Protein HRI1 Acetyltransf_10 PF13673.7 KIY48476.1 - 8.7e-11 41.9 0.0 1.3e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY48476.1 - 1.5e-07 31.6 0.0 2.1e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY48476.1 - 3.5e-07 30.5 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY48476.1 - 0.0045 16.9 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIY48476.1 - 0.057 13.5 0.1 0.092 12.8 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LapA_dom PF06305.11 KIY48477.1 - 0.8 9.6 4.2 0.5 10.2 0.5 2.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain zf-RING_5 PF14634.6 KIY48478.1 - 2.4e-05 24.2 5.8 3.9e-05 23.5 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY48478.1 - 0.0011 18.7 5.4 0.0019 18.0 5.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KIY48478.1 - 0.002 17.9 7.4 0.0035 17.2 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KIY48478.1 - 0.0058 16.4 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KIY48478.1 - 0.071 13.5 6.9 0.13 12.7 6.9 1.4 1 0 0 1 1 1 0 Ring finger domain Siva PF05458.12 KIY48478.1 - 0.1 12.3 2.3 0.21 11.3 2.3 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_UBOX PF13445.6 KIY48478.1 - 0.47 10.5 3.8 0.55 10.3 2.6 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY48478.1 - 1.2 9.0 7.2 2.5 8.0 7.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY48478.1 - 7.5 6.8 6.4 16 5.7 6.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ctr PF04145.15 KIY48479.1 - 2.6e-06 28.1 0.2 3.9e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DAO PF01266.24 KIY48480.1 - 2.6e-06 27.3 0.1 2.7e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY48480.1 - 0.0055 16.9 0.4 0.011 15.9 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY48480.1 - 0.02 14.0 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KIY48480.1 - 0.03 13.5 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY48480.1 - 0.04 13.1 0.2 0.064 12.5 0.2 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KIY48480.1 - 0.084 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KIY48480.1 - 0.092 12.4 0.8 0.14 11.8 0.8 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KIY48480.1 - 0.11 12.0 0.6 0.18 11.4 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KIY48481.1 - 3.3e-32 112.5 2.1 6.1e-32 111.6 2.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY48481.1 - 0.011 15.9 0.4 0.035 14.4 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY48481.1 - 0.039 13.0 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NADH_dh_m_C1 PF15088.6 KIY48481.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Pyr_redox_2 PF07992.14 KIY48481.1 - 0.046 12.9 0.5 0.14 11.4 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY48481.1 - 0.1 11.8 0.2 0.21 10.8 0.2 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KIY48481.1 - 0.11 12.5 0.1 2 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 KIY48481.1 - 0.16 11.6 0.4 0.29 10.8 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KIY48481.1 - 0.29 10.4 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KIY48481.1 - 0.31 10.6 0.6 0.55 9.8 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KIY48481.1 - 0.79 8.4 1.9 3.6 6.2 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Transp_cyt_pur PF02133.15 KIY48482.1 - 1.2e-99 334.1 44.9 1.4e-99 333.8 44.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin S1-P1_nuclease PF02265.16 KIY48484.1 - 2.9e-45 155.1 0.0 2.9e-41 142.0 0.0 2.5 2 1 0 2 2 2 2 S1/P1 Nuclease WD40 PF00400.32 KIY48485.1 - 1.3e-50 168.3 26.8 4.8e-11 43.0 1.4 7.6 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY48485.1 - 3.2e-20 72.2 2.4 0.002 18.4 0.0 6.7 3 3 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY48485.1 - 8.4e-08 31.5 0.3 0.86 8.5 0.0 4.5 2 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIY48485.1 - 0.00054 19.9 0.1 1.8 8.4 0.0 3.0 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KIY48485.1 - 0.0017 17.5 0.2 0.23 10.5 0.0 2.9 2 1 1 3 3 3 2 Coatomer WD associated region PD40 PF07676.12 KIY48485.1 - 0.015 15.2 10.6 0.42 10.6 0.3 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KIY48485.1 - 0.019 13.7 3.7 0.94 8.2 0.0 2.8 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.12 KIY48485.1 - 0.051 11.6 4.6 2.6 5.9 0.2 3.0 2 1 0 2 2 2 0 IKI3 family CRT10 PF08728.10 KIY48485.1 - 0.23 9.6 0.0 0.32 9.1 0.0 1.2 1 0 0 1 1 1 0 CRT10 Alpha-amylase PF00128.24 KIY48486.1 - 2.1e-18 67.0 2.6 4.1e-17 62.8 2.6 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIY48486.1 - 2.5e-12 47.1 0.0 5.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain ALC PF17527.2 KIY48487.1 - 0.16 11.6 1.2 0.28 10.8 1.2 1.3 1 0 0 1 1 1 0 Phage ALC protein SAA PF00277.18 KIY48487.1 - 3.3 8.2 9.8 0.67 10.5 5.9 1.9 2 0 0 2 2 2 0 Serum amyloid A protein Complex1_49kDa PF00346.19 KIY48488.1 - 9e-121 402.1 0.0 1.2e-120 401.7 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KIY48488.1 - 0.0048 15.9 0.0 0.0082 15.1 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Alpha-amylase PF00128.24 KIY48489.1 - 7.8e-17 61.8 3.0 6e-15 55.6 3.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIY48489.1 - 3.2e-12 46.7 0.0 8.7e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Aminotran_1_2 PF00155.21 KIY48490.1 - 3.4e-55 187.7 0.0 4.1e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIY48490.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase UNC-50 PF05216.13 KIY48492.1 - 1.2e-83 280.1 15.4 1.3e-83 279.9 15.4 1.0 1 0 0 1 1 1 1 UNC-50 family WW PF00397.26 KIY48493.1 - 3.9e-09 36.4 2.7 1.1e-08 35.0 2.7 1.8 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 KIY48493.1 - 0.083 13.2 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain CorA PF01544.18 KIY48494.1 - 1.1e-09 38.0 2.2 2.1e-09 37.1 2.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1465 PF07323.12 KIY48494.1 - 0.0088 15.9 6.1 0.04 13.8 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1465) Retrotran_gag_2 PF14223.6 KIY48494.1 - 0.081 12.6 2.0 0.21 11.2 2.0 1.5 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4532 PF15046.6 KIY48494.1 - 0.18 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) DUF16 PF01519.16 KIY48494.1 - 0.38 11.3 3.2 1.5 9.3 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 ProRS-C_1 PF09180.11 KIY48495.1 - 5.6e-26 90.6 0.3 1.1e-25 89.6 0.3 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KIY48495.1 - 9.5e-19 67.4 0.0 2.1e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIY48495.1 - 1.2e-18 67.7 0.0 2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 KIY48495.1 - 5.1e-09 36.2 0.0 9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain zf-ribbon_3 PF13248.6 KIY48495.1 - 0.11 11.9 0.3 0.22 11.0 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Oxysterol_BP PF01237.18 KIY48496.1 - 1.6e-44 152.2 0.0 1e-41 143.0 0.0 2.8 1 1 0 1 1 1 1 Oxysterol-binding protein DUF5589 PF17672.1 KIY48496.1 - 0.039 13.9 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5589) DUF1411 PF07199.11 KIY48496.1 - 0.039 13.6 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) HTH_29 PF13551.6 KIY48498.1 - 6.8e-09 35.6 0.0 8.6e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KIY48498.1 - 2e-07 30.6 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KIY48498.1 - 6.3e-07 29.4 0.0 9.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.18 KIY48498.1 - 1.7e-05 24.7 0.0 1.8e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 KIY48498.1 - 0.00038 21.0 0.0 0.0021 18.6 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 KIY48498.1 - 0.0055 16.7 0.0 0.0071 16.4 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_1 PF01527.20 KIY48498.1 - 0.0078 16.5 0.0 0.009 16.3 0.0 1.1 1 0 0 1 1 1 1 Transposase Terminase_5 PF06056.12 KIY48498.1 - 0.017 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) MerR_1 PF13411.6 KIY48498.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 1 0 1 1 1 0 MerR HTH family regulatory protein DDE_3 PF13358.6 KIY48499.1 - 2e-06 27.7 0.0 2.1e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease MRP-L28 PF09812.9 KIY48500.1 - 0.11 12.6 0.7 0.16 12.1 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 RE_AspBHI_N PF18062.1 KIY48501.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal Glyco_hydro_61 PF03443.14 KIY48502.1 - 1.6e-26 93.5 0.0 1.9e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-RVT PF13966.6 KIY48503.1 - 8e-07 29.7 0.3 8e-07 29.7 0.3 1.9 2 2 0 2 2 2 1 zinc-binding in reverse transcriptase DUF2199 PF09965.9 KIY48503.1 - 0.02 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) DPPIV_N PF00930.21 KIY48503.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Noc2 PF03715.13 KIY48506.1 - 1.8e-116 388.6 0.5 3.3e-116 387.7 0.5 1.4 1 0 0 1 1 1 1 Noc2p family U3snoRNP10 PF12397.8 KIY48506.1 - 0.12 12.8 1.8 0.44 10.9 0.7 2.3 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 BUD22 PF09073.10 KIY48506.1 - 3.3 6.9 19.1 5.2 6.3 19.1 1.3 1 0 0 1 1 1 0 BUD22 DUF1664 PF07889.12 KIY48507.1 - 0.00052 20.0 7.4 0.00052 20.0 7.4 6.0 3 2 3 6 6 6 1 Protein of unknown function (DUF1664) KxDL PF10241.9 KIY48507.1 - 0.0072 16.6 1.6 0.0072 16.6 1.6 5.7 4 2 2 6 6 6 1 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 KIY48507.1 - 0.026 14.6 100.1 0.12 12.4 20.9 6.0 1 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MMTV_SAg PF01054.17 KIY48507.1 - 0.27 10.8 9.0 0.63 9.6 0.7 3.0 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen APG6_N PF17675.1 KIY48507.1 - 0.31 11.6 110.8 0.058 13.9 14.7 6.6 2 2 4 6 6 6 0 Apg6 coiled-coil region Gp_dh_C PF02800.20 KIY48508.1 - 2.4e-66 222.2 0.0 3.2e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KIY48508.1 - 4.8e-38 129.6 0.0 1.1e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KIY48508.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KIY48508.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M48 PF01435.18 KIY48509.1 - 8.7e-14 51.7 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 COesterase PF00135.28 KIY48510.1 - 2.1e-89 300.8 0.0 3.2e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY48510.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY48510.1 - 0.0098 15.4 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AA_permease_2 PF13520.6 KIY48512.1 - 1.3e-56 192.3 47.1 1.5e-56 192.0 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY48512.1 - 2.6e-17 62.6 40.7 4.7e-17 61.7 40.7 1.3 1 1 0 1 1 1 1 Amino acid permease COesterase PF00135.28 KIY48513.1 - 1.4e-86 291.4 0.0 2e-86 290.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIY48513.1 - 0.0089 15.5 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIY48513.1 - 0.013 15.4 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Pan3_PK PF18101.1 KIY48514.1 - 5e-64 214.4 0.0 8.3e-64 213.7 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KIY48514.1 - 9.7e-05 21.9 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48514.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Abhydro_lipase PF04083.16 KIY48514.1 - 1.3 8.7 3.7 0.68 9.6 0.1 2.3 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region Amidohydro_3 PF07969.11 KIY48515.1 - 2.8e-79 267.8 0.1 3.5e-79 267.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIY48515.1 - 1.1e-10 41.3 0.0 5e-07 29.4 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family LSM PF01423.22 KIY48516.1 - 7.4e-20 70.4 0.0 9.2e-20 70.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain HEAT_EZ PF13513.6 KIY48517.1 - 6e-16 58.6 7.4 4.4e-09 36.7 0.0 8.2 9 0 0 9 9 8 2 HEAT-like repeat HEAT PF02985.22 KIY48517.1 - 2.5e-13 49.0 7.3 0.0035 17.5 0.0 9.7 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 KIY48517.1 - 4.7e-09 36.5 11.3 0.067 13.6 0.1 7.2 5 2 2 8 8 8 2 HEAT repeats IBN_N PF03810.19 KIY48517.1 - 7.2e-09 35.4 0.1 1.4e-07 31.3 0.0 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 KIY48517.1 - 5.7e-07 29.4 7.9 0.004 17.1 0.1 5.8 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KIY48517.1 - 1.3e-06 27.8 0.9 0.00089 18.5 0.0 3.3 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KIY48517.1 - 1.6e-06 28.1 0.5 1.2 9.0 0.2 5.3 4 1 2 6 6 6 2 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KIY48517.1 - 0.00024 20.7 0.3 2.1 7.8 0.1 3.6 2 1 1 3 3 3 2 CLASP N terminal RIX1 PF08167.12 KIY48517.1 - 0.0026 17.5 3.1 3.4 7.4 0.0 4.7 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 KIY48517.1 - 0.0032 16.1 0.3 8.5 4.8 0.0 4.1 4 1 0 4 4 4 1 Adaptin N terminal region DRIM PF07539.12 KIY48517.1 - 0.004 15.5 0.2 0.022 13.1 0.1 2.4 2 1 0 2 2 2 1 Down-regulated in metastasis TIP120 PF08623.10 KIY48517.1 - 0.034 13.9 1.1 0.57 9.9 0.0 3.0 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) IFRD PF05004.13 KIY48517.1 - 0.038 13.1 0.4 3.7 6.6 0.0 3.6 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) HSP70 PF00012.20 KIY48518.1 - 1.5e-84 284.4 0.4 3.9e-84 283.0 0.4 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY48518.1 - 4.9e-05 22.3 0.9 6.9e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein DUF1539 PF07560.11 KIY48518.1 - 0.12 12.4 0.2 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Blt1 PF12754.7 KIY48518.1 - 6.8 7.0 7.6 0.37 11.1 1.6 1.9 2 0 0 2 2 2 0 Blt1 N-terminal domain COesterase PF00135.28 KIY48520.1 - 1.2e-78 265.3 0.0 1.6e-78 264.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY48520.1 - 0.0029 17.5 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY48520.1 - 0.0047 16.4 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family CNTF PF01110.17 KIY48522.1 - 0.052 12.9 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor DUF4686 PF15742.5 KIY48523.1 - 0.04 13.0 0.2 0.059 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) APH PF01636.23 KIY48524.1 - 1.5e-14 54.5 0.5 5.3e-14 52.7 0.5 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY48524.1 - 0.00067 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KIY48524.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 KIY48524.1 - 0.028 13.8 0.1 0.058 12.8 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_GDSL_2 PF13472.6 KIY48525.1 - 2e-08 34.9 0.1 3e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY48525.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HMG_box PF00505.19 KIY48526.1 - 3.8e-24 84.9 1.9 6.6e-24 84.1 1.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY48526.1 - 2.3e-17 63.3 5.4 2.3e-17 63.3 5.4 1.7 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 KIY48526.1 - 0.00044 20.1 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 KIY48526.1 - 0.029 14.9 0.4 0.029 14.9 0.4 1.8 1 1 1 2 2 2 0 YABBY protein CE2_N PF17996.1 KIY48527.1 - 2.5e-08 33.9 1.0 0.00066 19.6 0.1 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal DUF4690 PF15756.5 KIY48527.1 - 0.028 15.0 1.6 0.068 13.8 0.1 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage RicinB_lectin_2 PF14200.6 KIY48527.1 - 0.076 13.8 7.0 0.45 11.3 0.1 3.5 3 1 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Syndecan PF01034.20 KIY48527.1 - 0.32 10.9 1.2 0.84 9.6 1.2 1.6 1 0 0 1 1 1 0 Syndecan domain ALO PF04030.14 KIY48528.1 - 1.9e-72 244.2 0.4 2.4e-72 243.9 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIY48528.1 - 4.1e-26 91.4 0.0 7.6e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain UQ_con PF00179.26 KIY48529.1 - 1.9e-46 157.2 0.0 2.2e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY48529.1 - 0.059 13.1 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B Membr_traf_MHD PF10540.9 KIY48530.1 - 5.6e-25 88.3 0.1 1.7e-11 44.5 0.0 3.1 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KIY48530.1 - 2.3e-12 47.1 0.0 5.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain Het-C PF07217.11 KIY48530.1 - 2.2 6.7 5.5 1.3 7.5 2.5 2.1 3 0 0 3 3 3 0 Heterokaryon incompatibility protein Het-C Cullin_binding PF03556.15 KIY48533.1 - 1.2e-33 116.1 0.2 1.7e-33 115.6 0.2 1.2 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KIY48533.1 - 2.4e-06 27.3 0.0 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UQ_con PF00179.26 KIY48534.1 - 1.7e-34 118.4 0.0 2e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY48534.1 - 0.00082 19.1 0.0 0.0013 18.4 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B Peptidase_S41 PF03572.18 KIY48535.1 - 2.2e-05 24.1 0.0 7.4e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 tRNA-synt_1 PF00133.22 KIY48536.1 - 1.5e-30 106.1 0.0 8.2e-20 70.6 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIY48536.1 - 3e-16 59.7 0.3 1.3e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIY48536.1 - 4e-14 52.2 0.0 1.6e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KIY48536.1 - 8.5e-06 25.3 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Kelch_1 PF01344.25 KIY48537.1 - 8.4e-38 127.7 13.7 1.2e-07 31.1 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KIY48537.1 - 8.5e-37 124.6 7.4 2.4e-10 40.2 0.5 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KIY48537.1 - 6.8e-36 122.0 20.4 5e-07 29.6 0.1 6.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KIY48537.1 - 3.7e-33 112.7 15.2 1.5e-07 31.5 0.1 6.2 4 2 2 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KIY48537.1 - 6.3e-32 109.2 14.3 6e-07 29.6 0.2 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KIY48537.1 - 5.8e-31 105.3 9.7 8.3e-06 25.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Epimerase PF01370.21 KIY48538.1 - 1.5e-13 50.8 0.7 1.9e-13 50.4 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY48538.1 - 3.1e-12 46.8 0.1 5e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY48538.1 - 3.5e-09 36.1 0.0 5.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY48538.1 - 2.6e-05 23.5 0.3 0.0012 18.1 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KIY48538.1 - 7.8e-05 22.3 0.6 0.00014 21.5 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KIY48538.1 - 0.00039 19.9 0.0 0.00065 19.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIY48538.1 - 0.15 11.2 0.1 0.26 10.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Got1 PF04178.12 KIY48540.1 - 1e-27 96.8 11.5 1.4e-27 96.3 11.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Herpes_LMP1 PF05297.11 KIY48540.1 - 3 6.9 5.9 4.1 6.5 5.9 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Oxysterol_BP PF01237.18 KIY48541.1 - 2e-60 204.6 0.1 5.6e-58 196.6 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein zf-MYND PF01753.18 KIY48542.1 - 5.1e-09 36.1 11.1 5.1e-09 36.1 11.1 2.5 3 0 0 3 3 3 1 MYND finger Exotox-A_bind PF09101.10 KIY48542.1 - 0.2 11.0 0.0 5.9 6.2 0.0 2.8 2 1 1 3 3 3 0 Exotoxin A binding Histone PF00125.24 KIY48543.1 - 2.2e-19 70.1 0.0 2.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIY48543.1 - 4.8e-12 45.4 0.2 1e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIY48543.1 - 0.017 15.4 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 KIY48544.1 - 8e-64 215.5 0.0 9.1e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48544.1 - 9.8e-38 129.9 0.0 1.2e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY48544.1 - 1.9e-07 30.7 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY48544.1 - 6.3e-06 25.4 0.5 8.1e-06 25.0 0.5 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIY48544.1 - 0.00015 21.4 0.1 0.00022 20.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY48544.1 - 0.0034 17.3 1.0 0.013 15.4 0.5 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KIY48544.1 - 0.016 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KIY48544.1 - 0.044 12.6 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Phage_T7_Capsid PF05396.11 KIY48544.1 - 0.086 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein KA1 PF02149.19 KIY48545.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Glyco_hydro_88 PF07470.13 KIY48546.1 - 2.2e-32 112.5 0.0 2.7e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 p450 PF00067.22 KIY48547.1 - 3.3e-35 121.7 0.0 7e-35 120.7 0.0 1.5 1 1 1 2 2 2 1 Cytochrome P450 Peptidase_C14 PF00656.22 KIY48548.1 - 7.2e-08 32.7 0.0 8.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Caspase domain TrkH PF02386.16 KIY48549.1 - 2.7e-83 280.1 12.4 2.2e-82 277.1 2.4 2.1 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.16 KIY48549.1 - 3.1 7.8 9.2 21 5.2 9.2 2.5 1 0 0 1 1 1 0 Ion channel Mito_carr PF00153.27 KIY48550.1 - 2.2e-63 210.2 3.2 5.8e-22 77.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Lyase_1 PF00206.20 KIY48552.1 - 2.8e-21 76.2 0.0 4e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KIY48552.1 - 6.1e-18 65.1 0.0 2.9e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF3336 PF11815.8 KIY48553.1 - 3.1 7.5 5.4 5 6.8 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) DASH_Spc19 PF08287.11 KIY48553.1 - 9.5 6.1 18.6 3.8 7.4 15.9 1.7 2 0 0 2 2 2 0 Spc19 PseudoU_synth_1 PF01416.20 KIY48554.1 - 2.8e-22 79.2 0.0 1e-21 77.4 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridine synthase Histidinol_dh PF00815.20 KIY48554.1 - 0.25 10.3 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase EGF_Tenascin PF18720.1 KIY48555.1 - 0.042 13.9 0.5 0.13 12.4 0.5 1.8 1 0 0 1 1 1 0 Tenascin EGF domain SAP130_C PF16014.5 KIY48555.1 - 3.2 6.8 12.7 4.5 6.3 12.7 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DUF5585 PF17823.1 KIY48555.1 - 3.5 6.5 32.9 5.2 5.9 32.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Peptidase_C14 PF00656.22 KIY48556.1 - 4.6e-23 82.5 0.0 7.5e-23 81.8 0.0 1.2 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KIY48556.1 - 0.0026 17.7 0.6 0.011 15.7 0.4 2.1 2 1 0 2 2 2 1 Raptor N-terminal CASPase like domain Peptidase_C65 PF10275.9 KIY48557.1 - 9.8e-68 228.2 0.0 1.1e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KIY48557.1 - 0.00046 20.7 0.0 0.7 10.4 0.0 2.6 3 0 0 3 3 3 2 OTU-like cysteine protease Peptidase_C101 PF16218.5 KIY48557.1 - 0.055 12.7 0.0 8.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase family C101 PPR_3 PF13812.6 KIY48559.1 - 0.0042 17.1 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 KIY48559.1 - 0.0077 16.4 2.0 8.5 6.7 0.7 3.6 2 1 0 2 2 2 2 PPR repeat family RNA_pol PF00940.19 KIY48560.1 - 2.6e-177 589.8 0.0 3.3e-177 589.5 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KIY48560.1 - 3.8e-88 296.1 0.0 7.4e-88 295.1 0.0 1.5 1 1 0 1 1 1 1 DNA-directed RNA polymerase N-terminal APG6_N PF17675.1 KIY48560.1 - 0.14 12.6 1.0 0.46 11.0 0.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region F-box-like PF12937.7 KIY48561.1 - 9.4e-08 31.8 0.6 9.4e-08 31.8 0.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY48561.1 - 2e-07 30.7 0.6 6.2e-07 29.1 0.6 1.8 1 0 0 1 1 1 1 F-box domain ATP_sub_h PF10775.9 KIY48562.1 - 1.7e-24 85.6 1.5 1.1e-23 83.0 0.8 2.0 2 0 0 2 2 2 1 ATP synthase complex subunit h DUF1179 PF06678.11 KIY48562.1 - 0.054 13.5 0.4 0.077 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) IATP PF04568.12 KIY48563.1 - 1.6e-05 25.3 1.8 1.8e-05 25.1 1.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP p450 PF00067.22 KIY48564.1 - 5.5e-06 25.4 0.0 6.8e-06 25.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_12 PF13087.6 KIY48565.1 - 1.4e-24 86.8 0.0 3.1e-11 43.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 KIY48565.1 - 1.7e-12 47.7 0.0 2.8e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY48565.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 KIY48566.1 - 1.1e-62 212.3 0.0 1.4e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SKN1 PF03935.15 KIY48568.1 - 4.6e-185 615.8 8.3 5.7e-185 615.5 8.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Tcf25 PF04910.14 KIY48569.1 - 1.4e-85 287.5 0.5 2.1e-85 286.9 0.5 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF3952 PF13130.6 KIY48569.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) NAM-associated PF14303.6 KIY48569.1 - 1.8 9.2 7.2 3.8 8.2 7.2 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DHHC PF01529.20 KIY48570.1 - 1.4e-37 128.8 8.0 1.4e-37 128.8 8.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF5009 PF16401.5 KIY48570.1 - 0.04 13.4 1.9 0.069 12.6 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) Spt4 PF06093.13 KIY48570.1 - 0.72 10.0 4.0 1.5 9.0 4.0 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Rab5-bind PF09311.11 KIY48571.1 - 0.057 12.8 0.3 7.9 5.8 0.1 2.2 2 0 0 2 2 2 0 Rabaptin-like protein AAA PF00004.29 KIY48572.1 - 2.4e-76 254.5 0.0 9.4e-42 142.6 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY48572.1 - 6.9e-12 45.0 0.1 1.7e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIY48572.1 - 2.7e-09 37.6 1.0 9.8e-08 32.6 0.5 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY48572.1 - 6.8e-09 36.1 0.1 0.0002 21.7 0.1 3.5 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KIY48572.1 - 1.4e-08 35.0 0.0 0.0041 17.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KIY48572.1 - 4.6e-08 33.2 0.1 2e-06 27.8 0.0 3.4 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIY48572.1 - 1e-06 28.6 0.1 0.00014 21.7 0.0 3.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIY48572.1 - 6.9e-05 23.0 0.0 0.00019 21.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY48572.1 - 0.00016 21.5 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 KIY48572.1 - 0.00028 20.8 0.1 0.015 15.2 0.0 3.3 4 0 0 4 4 4 1 NACHT domain TIP49 PF06068.13 KIY48572.1 - 0.00095 18.5 0.0 0.003 16.8 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 KIY48572.1 - 0.0024 17.5 2.3 1.3 8.6 0.0 3.6 3 1 1 4 4 3 1 AAA domain DAP3 PF10236.9 KIY48572.1 - 0.0056 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_11 PF13086.6 KIY48572.1 - 0.0057 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIY48572.1 - 0.008 15.5 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 KIY48572.1 - 0.0096 16.2 0.1 0.029 14.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KIY48572.1 - 0.0097 15.6 0.0 0.027 14.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 KIY48572.1 - 0.011 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KIY48572.1 - 0.011 16.3 0.0 0.023 15.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIY48572.1 - 0.011 14.8 0.0 0.045 12.9 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIY48572.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KIY48572.1 - 0.02 14.8 0.0 7.8 6.3 0.0 3.0 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KIY48572.1 - 0.02 14.9 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KIY48572.1 - 0.022 14.6 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Mg_chelatase PF01078.21 KIY48572.1 - 0.048 13.0 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KIY48572.1 - 0.074 12.8 0.0 0.73 9.5 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 KIY48572.1 - 0.11 11.6 0.0 0.93 8.6 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_3 PF07726.11 KIY48572.1 - 0.12 12.2 0.0 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIY48572.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIY48572.1 - 0.16 12.3 0.1 0.74 10.1 0.0 2.1 3 0 0 3 3 1 0 AAA domain Viral_helicase1 PF01443.18 KIY48572.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KIY48572.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 NTPase RNase_P_Rpp14 PF01900.19 KIY48573.1 - 0.00096 19.4 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family BfiI_DBD PF18243.1 KIY48573.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain Kinetochor_Ybp2 PF08568.10 KIY48575.1 - 5.6e-18 64.8 0.2 8e-18 64.3 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin p450 PF00067.22 KIY48576.1 - 2e-58 198.3 0.0 1.3e-57 195.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Gram_pos_anchor PF00746.21 KIY48576.1 - 8.6 6.4 8.5 0.18 11.7 1.6 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif AAA PF00004.29 KIY48579.1 - 7.1e-85 282.1 0.0 1.6e-41 141.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY48579.1 - 2.6e-23 81.6 1.3 3.4e-11 42.8 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KIY48579.1 - 7.7e-13 48.5 0.0 0.00013 21.7 0.0 3.5 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIY48579.1 - 3.5e-12 47.0 5.3 3.6e-07 30.7 0.3 4.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 KIY48579.1 - 2.3e-11 43.8 0.1 2.3e-06 27.6 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY48579.1 - 2.5e-10 40.8 0.5 7.9e-05 22.9 0.0 4.3 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KIY48579.1 - 4e-10 40.1 0.0 0.00098 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KIY48579.1 - 2e-08 34.5 0.0 0.00027 21.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KIY48579.1 - 4.5e-08 32.7 0.0 0.0027 17.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 KIY48579.1 - 7.5e-08 32.3 0.0 0.00045 20.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 KIY48579.1 - 1.3e-05 25.2 0.0 0.027 14.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIY48579.1 - 2.6e-05 24.2 0.2 0.019 14.9 0.0 4.3 5 0 0 5 5 5 1 NACHT domain AAA_14 PF13173.6 KIY48579.1 - 0.00011 22.3 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KIY48579.1 - 0.00011 22.5 0.0 0.043 14.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KIY48579.1 - 0.00012 21.8 2.8 0.43 10.1 0.2 3.9 2 2 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KIY48579.1 - 0.00013 21.4 0.2 0.15 11.5 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KIY48579.1 - 0.00015 22.1 0.0 0.039 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KIY48579.1 - 0.00029 20.2 0.0 0.023 14.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 KIY48579.1 - 0.00036 20.4 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KIY48579.1 - 0.0015 18.4 0.0 0.39 10.5 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_18 PF13238.6 KIY48579.1 - 0.0017 18.9 0.0 0.03 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIY48579.1 - 0.002 17.9 0.0 0.42 10.3 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KIY48579.1 - 0.0025 17.3 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DAP3 PF10236.9 KIY48579.1 - 0.0031 16.7 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_3 PF07726.11 KIY48579.1 - 0.0033 17.3 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIY48579.1 - 0.0063 16.3 0.0 0.034 13.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 KIY48579.1 - 0.0084 16.0 0.0 27 4.6 0.0 3.5 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KIY48579.1 - 0.0087 16.0 0.0 0.65 9.9 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain Sigma54_activat PF00158.26 KIY48579.1 - 0.0091 15.7 0.0 1.2 8.8 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KIY48579.1 - 0.014 14.5 0.0 0.057 12.5 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KIY48579.1 - 0.021 14.6 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIY48579.1 - 0.024 13.8 0.0 0.92 8.6 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) PhoH PF02562.16 KIY48579.1 - 0.029 13.8 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 KIY48579.1 - 0.043 14.3 0.0 2.4 8.7 0.0 3.0 2 1 0 3 3 3 0 ABC transporter AAA_19 PF13245.6 KIY48579.1 - 0.058 13.7 0.1 0.85 10.0 0.0 2.7 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 KIY48579.1 - 0.068 13.1 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 NTPase ATPase PF06745.13 KIY48579.1 - 0.072 12.4 0.0 5.3 6.3 0.0 2.4 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 KIY48579.1 - 0.087 12.9 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 KIY48579.1 - 0.11 11.7 0.0 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AFG1_ATPase PF03969.16 KIY48579.1 - 0.19 10.6 0.0 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase DUF3724 PF12521.8 KIY48583.1 - 0.016 15.1 0.5 0.033 14.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) CsbD PF05532.12 KIY48583.1 - 0.024 14.5 0.5 0.024 14.5 0.5 1.5 2 0 0 2 2 2 0 CsbD-like SNase PF00565.17 KIY48584.1 - 1.2e-17 64.3 0.0 1.9e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue NuA4 PF09340.10 KIY48586.1 - 7.8e-25 86.6 2.2 1.5e-24 85.7 0.1 2.1 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF4165 PF13752.6 KIY48586.1 - 0.062 13.3 0.6 0.1 12.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) DUF677 PF05055.12 KIY48587.1 - 0.2 10.5 1.3 0.44 9.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF677) HEM4 PF02602.15 KIY48589.1 - 8.6e-25 87.4 0.0 1.1e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Alpha-amylase_N PF02903.14 KIY48590.1 - 0.19 11.9 0.0 5.7 7.1 0.0 2.6 2 1 0 2 2 2 0 Alpha amylase, N-terminal ig-like domain Aminotran_3 PF00202.21 KIY48591.1 - 3.9e-111 371.6 0.0 4.5e-111 371.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIY48591.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II P16-Arc PF04699.14 KIY48592.1 - 6.9e-52 175.9 0.0 7.7e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KIY48592.1 - 0.0035 17.6 0.0 0.0061 16.9 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF2711 PF10924.8 KIY48592.1 - 0.057 13.0 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) HSP20 PF00011.21 KIY48593.1 - 2.6e-16 59.6 0.1 8.6e-10 38.7 0.0 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY48593.1 - 3.7e-09 36.0 0.0 1.1e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 KIY48593.1 - 0.0017 18.4 0.1 1.1 9.4 0.1 2.2 2 0 0 2 2 2 2 FKBP26_C-terminal HCBP_related PF06594.11 KIY48593.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain Asp_Glu_race PF01177.22 KIY48594.1 - 6.7e-06 26.1 0.1 2.7e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase NPV_P10 PF05531.12 KIY48596.1 - 0.00031 21.1 0.5 0.00063 20.2 0.5 1.5 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KIY48596.1 - 0.011 15.7 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KIY48596.1 - 0.022 15.1 0.4 1.4 9.3 0.2 2.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KIY48596.1 - 0.024 14.7 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 KIY48596.1 - 0.053 14.0 0.7 0.062 13.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 LPP PF04728.13 KIY48596.1 - 0.054 13.9 0.6 0.96 9.9 0.2 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper MtrB PF05440.12 KIY48596.1 - 0.072 13.5 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B PEMT PF04191.13 KIY48597.1 - 2e-54 182.5 6.9 1.8e-30 105.4 0.3 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 KIY48597.1 - 0.025 14.4 0.2 0.069 12.9 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KIY48597.1 - 0.044 14.3 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 SKICH domain YvbH_ext PF11724.8 KIY48597.1 - 0.17 12.3 0.3 0.57 10.5 0.3 1.9 1 0 0 1 1 1 0 YvbH-like oligomerisation region Pkinase PF00069.25 KIY48598.1 - 1.7e-22 80.1 0.0 1.8e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48598.1 - 3e-11 43.1 0.0 3.1e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY48598.1 - 1.8e-06 27.5 0.0 2e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY48598.1 - 2.4e-05 23.3 0.0 2.6e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY48598.1 - 0.0023 17.9 0.1 0.003 17.5 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY48598.1 - 0.012 14.6 0.3 0.014 14.4 0.3 1.0 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KIY48598.1 - 0.086 12.4 0.4 0.11 12.0 0.4 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIY48598.1 - 0.13 11.6 0.2 0.14 11.5 0.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0016 PF01169.19 KIY48599.1 - 2.5e-43 146.3 19.4 5.1e-23 81.2 8.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 OFeT_1 PF16955.5 KIY48599.1 - 0.0067 16.1 1.8 0.0085 15.8 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron uptake permease, iron-lead transporter DUF4131 PF13567.6 KIY48599.1 - 0.36 10.5 2.0 4.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3995 PF13160.6 KIY48599.1 - 0.52 10.7 13.5 1.9 8.9 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) TerC PF03741.16 KIY48599.1 - 1.5 8.5 11.6 0.1 12.3 3.1 2.5 2 1 0 2 2 2 0 Integral membrane protein TerC family AAA_22 PF13401.6 KIY48600.1 - 0.0083 16.4 0.0 0.77 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KIY48600.1 - 0.0098 15.3 0.1 3.7 6.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Zot PF05707.12 KIY48600.1 - 0.013 15.1 0.1 0.052 13.2 0.0 1.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_16 PF13191.6 KIY48600.1 - 0.025 15.0 0.0 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KIY48600.1 - 0.04 13.2 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 KIY48600.1 - 0.12 12.8 0.1 1.4 9.3 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KIY48600.1 - 0.12 12.1 0.1 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Abhydrolase_6 PF12697.7 KIY48601.1 - 2.6e-25 90.3 0.1 4.4e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY48601.1 - 7.8e-08 31.9 0.1 1.3e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY48601.1 - 1e-06 28.6 0.0 0.0043 16.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 KIY48601.1 - 1.4e-05 25.3 0.0 3e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KIY48601.1 - 0.09 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 KIY48601.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Methyltransf_32 PF13679.6 KIY48601.1 - 0.24 11.4 0.0 0.38 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PseudoU_synth_2 PF00849.22 KIY48602.1 - 3.1e-22 79.4 0.0 5.1e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase SUR7 PF06687.12 KIY48603.1 - 1.1e-17 64.4 9.7 1.6e-17 63.9 9.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KIY48603.1 - 0.0024 17.7 0.2 0.0038 17.0 0.2 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4293 PF14126.6 KIY48603.1 - 0.0043 17.3 0.5 0.011 16.0 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4293) Claudin_2 PF13903.6 KIY48603.1 - 0.0093 15.7 4.7 0.025 14.3 4.7 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KIY48603.1 - 0.02 14.7 8.3 0.2 11.5 8.3 2.2 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF503 PF04456.12 KIY48603.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF503) DUF4381 PF14316.6 KIY48603.1 - 0.13 12.5 0.7 0.29 11.4 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) DUF4481 PF14800.6 KIY48603.1 - 0.18 11.2 1.3 13 5.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) Phage_holin_3_6 PF07332.11 KIY48603.1 - 1.8 8.6 11.9 1.1 9.4 7.7 2.5 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Myb_DNA-binding PF00249.31 KIY48604.1 - 0.00068 19.8 0.3 0.0012 19.0 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Gpr1_Fun34_YaaH PF01184.19 KIY48605.1 - 7.8e-33 113.8 18.1 9.4e-33 113.6 18.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SWIB PF02201.18 KIY48606.1 - 3.5e-22 78.1 0.2 7.9e-22 76.9 0.0 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain DHR10 PF18595.1 KIY48607.1 - 9.1e-30 103.1 23.1 9.1e-30 103.1 23.1 4.4 3 2 1 4 4 4 1 Designed helical repeat protein 10 domain Nuf2 PF03800.14 KIY48607.1 - 1.2e-27 96.7 0.0 3.9e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family KASH_CCD PF14662.6 KIY48607.1 - 2.3e-05 24.3 5.5 2.3e-05 24.3 5.5 3.0 1 1 1 2 2 1 1 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KIY48607.1 - 0.00033 21.2 2.9 0.00033 21.2 2.9 4.1 3 1 1 4 4 4 1 Apg6 coiled-coil region HAP1_N PF04849.13 KIY48607.1 - 0.00052 19.3 3.6 0.00052 19.3 3.6 3.0 1 1 0 2 2 1 1 HAP1 N-terminal conserved region DUF4686 PF15742.5 KIY48607.1 - 0.00064 19.0 0.9 0.00064 19.0 0.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4686) DUF2968 PF11180.8 KIY48607.1 - 0.0036 17.0 3.2 0.0036 17.0 3.2 4.4 1 1 2 4 4 3 2 Protein of unknown function (DUF2968) Mod_r PF07200.13 KIY48607.1 - 0.0097 16.0 2.5 0.0097 16.0 2.5 3.4 1 1 1 3 3 3 1 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 KIY48607.1 - 0.012 15.0 39.3 0.21 10.9 3.2 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 KIY48607.1 - 0.014 16.0 0.9 0.014 16.0 0.9 6.8 3 2 3 6 6 5 0 SlyX DUF5101 PF17031.5 KIY48607.1 - 0.022 14.9 11.5 0.19 11.8 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5101) ZapB PF06005.12 KIY48607.1 - 0.024 15.1 4.4 0.024 15.1 4.4 5.4 2 2 1 3 3 2 0 Cell division protein ZapB YabA PF06156.13 KIY48607.1 - 0.037 14.7 26.0 0.29 11.8 1.9 4.6 1 1 2 3 3 3 0 Initiation control protein YabA DUF3584 PF12128.8 KIY48607.1 - 0.053 11.0 40.0 0.078 10.5 40.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KIY48607.1 - 0.15 12.1 20.5 1.4 9.0 0.6 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KIY48607.1 - 0.16 12.0 8.7 1.9 8.5 0.5 3.3 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CSN7a_helixI PF18392.1 KIY48607.1 - 0.3 11.0 2.3 1.5 8.8 0.3 3.2 1 1 1 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain NPV_P10 PF05531.12 KIY48607.1 - 1.2 9.7 12.3 12 6.4 0.6 4.5 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.12 KIY48607.1 - 1.9 8.9 38.3 0.073 13.5 1.1 4.3 1 1 3 4 4 4 0 Centromere protein H (CENP-H) Spc7 PF08317.11 KIY48607.1 - 3 6.6 39.5 0.075 11.9 5.1 2.8 1 1 0 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KIY48607.1 - 6.9 6.7 40.2 0.055 13.6 4.2 4.1 2 2 1 3 3 2 0 Afadin- and alpha -actinin-Binding Prefoldin PF02996.17 KIY48607.1 - 7.7 6.5 23.3 16 5.4 0.5 4.8 2 2 0 3 3 3 0 Prefoldin subunit Transformer PF06495.11 KIY48608.1 - 0.054 13.6 3.1 0.11 12.6 3.1 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Ras PF00071.22 KIY48609.1 - 3.3e-43 147.1 0.2 3.9e-43 146.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY48609.1 - 8.9e-17 61.4 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY48609.1 - 2.3e-09 37.0 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY48609.1 - 5.4e-06 26.5 0.0 7.2e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY48609.1 - 3.1e-05 23.6 0.5 0.00012 21.7 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KIY48609.1 - 0.00087 18.8 0.1 0.0013 18.2 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KIY48609.1 - 0.0044 16.6 0.0 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 KIY48609.1 - 0.0049 16.9 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIY48609.1 - 0.011 15.7 0.1 4.3 7.2 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase pXO2-34 PF17362.2 KIY48609.1 - 0.076 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function BAR PF03114.18 KIY48610.1 - 3.8e-36 124.9 8.7 4.7e-36 124.6 8.7 1.0 1 0 0 1 1 1 1 BAR domain DUF1640 PF07798.11 KIY48610.1 - 0.005 16.9 3.3 0.005 16.9 3.3 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1640) DUF932 PF06067.11 KIY48610.1 - 0.065 13.0 2.8 0.11 12.2 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF932) FapA PF03961.13 KIY48610.1 - 0.75 8.3 4.7 0.15 10.6 1.4 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4212 PF13937.6 KIY48611.1 - 0.39 11.1 7.8 0.49 10.8 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4212) O-FucT PF10250.9 KIY48612.1 - 1.9e-09 37.7 0.0 3e-08 33.7 0.0 2.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_hydro_30 PF02055.16 KIY48613.1 - 7.1e-19 68.0 0.9 1.3e-17 63.9 0.5 2.1 1 1 1 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KIY48613.1 - 1.9e-08 33.9 0.0 3.7e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KIY48613.1 - 0.00086 19.0 0.0 0.024 14.3 0.0 2.1 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Kelch_2 PF07646.15 KIY48613.1 - 0.084 12.9 1.7 0.87 9.7 0.3 2.8 2 0 0 2 2 2 0 Kelch motif Rtt106 PF08512.12 KIY48615.1 - 5.5e-21 74.8 0.0 9.6e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KIY48615.1 - 0.002 18.1 0.1 0.0035 17.3 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Stealth_CR2 PF11380.8 KIY48615.1 - 0.0023 18.1 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 YL1 PF05764.13 KIY48615.1 - 2.9 7.9 7.4 0.63 10.1 3.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Adaptin_N PF01602.20 KIY48616.1 - 2.4e-141 471.9 5.8 2.8e-141 471.6 5.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIY48616.1 - 7.6e-62 208.1 4.0 5.3e-61 205.4 0.5 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY48616.1 - 1.6e-17 63.6 3.1 1.9e-06 28.2 0.0 6.2 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 KIY48616.1 - 1.2e-10 40.7 8.9 0.00014 21.8 0.1 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KIY48616.1 - 1.3e-05 25.6 1.5 2 9.0 0.1 5.6 4 1 1 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 KIY48616.1 - 0.0012 19.0 0.9 0.79 9.9 0.0 3.9 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KIY48616.1 - 0.0012 18.4 0.1 0.39 10.3 0.0 3.1 2 1 0 2 2 2 1 CLASP N terminal Cnd3 PF12719.7 KIY48616.1 - 0.0035 16.6 0.5 0.15 11.2 0.1 2.5 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KIY48616.1 - 0.035 14.1 5.6 35 4.6 0.0 5.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 KIY48616.1 - 0.16 11.9 0.9 1.4 8.8 0.1 2.7 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ICMT PF04140.14 KIY48619.1 - 0.0071 16.7 0.2 3.1 8.3 0.0 2.3 2 0 0 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Plavaka PF18759.1 KIY48621.1 - 3.2e-20 72.6 0.9 3.6e-20 72.5 0.9 1.0 1 0 0 1 1 1 1 Plavaka transposase Pet20 PF08692.10 KIY48621.1 - 0.029 15.1 0.1 0.036 14.8 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Sin3a_C PF16879.5 KIY48624.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein F-box-like PF12937.7 KIY48625.1 - 0.00026 20.8 0.5 0.00071 19.4 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY48625.1 - 0.012 15.5 0.5 0.012 15.5 0.5 2.1 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 KIY48625.1 - 0.012 15.4 0.2 0.026 14.4 0.2 1.5 1 0 0 1 1 1 0 F-box Pkinase PF00069.25 KIY48628.1 - 3.2e-15 56.2 0.1 9.4e-14 51.4 0.1 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48628.1 - 1.7e-07 30.8 0.1 2.9e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L6 PF00347.23 KIY48629.1 - 3.7e-18 66.0 0.0 3.4e-10 40.5 0.0 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 Sld5 PF05916.11 KIY48630.1 - 0.0042 17.5 0.0 0.0064 16.9 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein Peptidase_M24_C PF16188.5 KIY48630.1 - 0.029 14.4 0.1 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 SLD5_C PF16922.5 KIY48630.1 - 0.06 13.5 0.4 0.13 12.5 0.4 1.5 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus SET PF00856.28 KIY48631.1 - 4.6e-11 43.4 0.0 7.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KIY48631.1 - 8.8e-05 22.5 18.4 0.00021 21.3 18.4 1.7 1 0 0 1 1 1 1 MYND finger SQS_PSY PF00494.19 KIY48633.1 - 9.6e-54 182.6 0.2 1.2e-53 182.3 0.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase ATP-synt_C PF00137.21 KIY48634.1 - 6.2e-31 106.5 31.6 1.7e-19 69.9 12.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C zf-CCHC_3 PF13917.6 KIY48635.1 - 3.7e-19 68.4 0.7 5.2e-19 67.9 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY48635.1 - 0.088 12.9 0.8 0.14 12.3 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle vATP-synt_AC39 PF01992.16 KIY48636.1 - 1.2e-113 380.0 0.9 1.4e-113 379.9 0.9 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 KIY48636.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain Epimerase PF01370.21 KIY48637.1 - 2.5e-18 66.4 0.0 4.8e-18 65.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY48637.1 - 5.3e-13 48.6 0.0 7.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIY48637.1 - 1.3e-12 48.0 0.1 2.1e-12 47.3 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIY48637.1 - 1.4e-08 34.2 0.0 1.8e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIY48637.1 - 7.8e-07 28.8 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIY48637.1 - 0.0001 22.0 0.6 0.00019 21.1 0.6 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KIY48637.1 - 0.0012 18.0 0.1 0.0032 16.7 0.0 1.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIY48637.1 - 0.028 13.9 0.1 0.061 12.8 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Tam41_Mmp37 PF09139.11 KIY48638.1 - 3.5e-113 378.3 0.0 4.2e-113 378.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Translin PF01997.16 KIY48639.1 - 4.5e-50 170.5 0.0 5.2e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF1664 PF07889.12 KIY48639.1 - 0.076 13.1 0.6 0.32 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF397 PF04149.12 KIY48640.1 - 0.056 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF397) Asp_protease_2 PF13650.6 KIY48641.1 - 0.0026 18.4 0.0 0.007 17.0 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease Peptidase_A2B PF12384.8 KIY48641.1 - 0.003 17.1 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP_2 PF08284.11 KIY48641.1 - 0.022 14.5 0.1 0.072 12.9 0.1 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIY48641.1 - 0.056 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4413 PF14372.6 KIY48642.1 - 0.00019 21.7 0.1 0.00029 21.2 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 KIY48643.1 - 9.4e-12 44.6 0.1 1.2e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TFIIS_C PF01096.18 KIY48644.1 - 1.1e-16 60.4 11.2 1.5e-16 59.9 2.4 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIY48644.1 - 1.7e-09 37.4 6.1 2.3e-07 30.6 0.6 2.8 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit IBR PF01485.21 KIY48644.1 - 2e-05 24.7 5.4 0.013 15.8 0.2 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-RING_7 PF02591.15 KIY48644.1 - 0.00033 20.8 7.5 2.7 8.2 0.5 4.0 4 0 0 4 4 4 2 C4-type zinc ribbon domain DZR PF12773.7 KIY48644.1 - 0.00044 20.2 10.2 0.009 16.0 0.2 2.7 2 1 0 2 2 2 1 Double zinc ribbon zinc_ribbon_4 PF13717.6 KIY48644.1 - 0.0021 17.9 8.3 0.12 12.3 0.4 3.5 3 1 0 3 3 3 1 zinc-ribbon domain Baculo_LEF5_C PF11792.8 KIY48644.1 - 0.0034 17.0 4.5 0.024 14.3 0.8 2.5 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain DUF523 PF04463.12 KIY48644.1 - 0.004 17.2 0.2 0.005 16.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) CpXC PF14353.6 KIY48644.1 - 0.0057 16.7 9.3 6.8 6.8 7.1 3.4 2 1 0 2 2 2 0 CpXC protein zf-NADH-PPase PF09297.11 KIY48644.1 - 0.0069 16.0 10.8 0.022 14.4 0.1 3.3 3 0 0 3 3 3 2 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 KIY48644.1 - 0.0076 15.6 12.2 0.29 10.6 0.1 4.1 4 0 0 4 4 4 2 zinc-ribbon domain zf_UBZ PF18439.1 KIY48644.1 - 0.015 14.9 9.6 4.8 6.9 0.2 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_10 PF10058.9 KIY48644.1 - 0.026 14.2 4.1 8.8 6.2 0.0 3.8 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 KIY48644.1 - 0.035 13.5 2.9 3.3 7.2 0.0 2.6 2 1 0 2 2 2 0 Mu-like prophage protein Com Ribosomal_S27e PF01667.17 KIY48644.1 - 0.036 13.8 6.6 0.24 11.1 0.3 2.7 3 0 0 3 3 2 0 Ribosomal protein S27 zf-C4_Topoisom PF01396.19 KIY48644.1 - 0.073 12.9 12.5 0.53 10.1 2.4 4.0 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Terminase_GpA PF05876.12 KIY48644.1 - 0.075 11.6 6.3 0.17 10.4 1.2 2.3 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) DUF3268 PF11672.8 KIY48644.1 - 0.08 13.3 0.4 0.08 13.3 0.4 2.4 2 1 1 3 3 3 0 zinc-finger-containing domain zinc_ribbon_2 PF13240.6 KIY48644.1 - 0.11 12.2 12.1 1.1 9.1 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 KIY48644.1 - 0.12 12.4 5.8 2.1 8.4 0.5 3.7 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger PHD PF00628.29 KIY48644.1 - 0.12 12.3 11.9 0.9 9.5 2.7 2.8 2 1 1 3 3 3 0 PHD-finger DNA_RNApol_7kD PF03604.13 KIY48644.1 - 0.19 11.4 8.3 7.3 6.4 0.1 3.6 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Nudix_N_2 PF14803.6 KIY48644.1 - 0.19 11.7 12.1 2.4 8.1 3.1 3.4 2 2 0 2 2 2 0 Nudix N-terminal HydF_tetramer PF18133.1 KIY48644.1 - 0.22 11.3 1.4 0.22 11.3 0.7 1.4 1 1 0 1 1 1 0 Hydrogen maturase F tetramerization domain Zn_Tnp_IS1595 PF12760.7 KIY48644.1 - 0.27 11.2 11.5 0.13 12.2 2.4 2.9 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.13 KIY48644.1 - 0.37 10.9 10.1 0.13 12.3 1.8 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KIY48644.1 - 0.37 10.9 13.4 4.2 7.6 0.1 4.1 3 1 2 5 5 5 0 Zinc ribbon domain DUF35_N PF12172.8 KIY48644.1 - 0.54 10.2 9.1 2.1 8.3 0.2 3.4 4 0 0 4 4 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2387 PF09526.10 KIY48644.1 - 0.65 10.2 7.2 8.9 6.6 2.1 2.6 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Methyltransf_13 PF08421.11 KIY48644.1 - 1.1 9.5 11.3 0.71 10.2 0.3 3.5 4 0 0 4 4 4 0 Putative zinc binding domain HscB_4_cys PF18256.1 KIY48644.1 - 1.4 8.8 0.1 1.4 8.8 0.1 3.0 4 0 0 4 4 3 0 Co-chaperone HscB tetracysteine metal binding motif UPF0547 PF10571.9 KIY48644.1 - 1.5 9.0 14.5 1.6 8.9 0.5 3.6 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 PhnA_Zn_Ribbon PF08274.12 KIY48644.1 - 2.3 8.2 17.6 12 5.9 0.2 4.0 3 1 1 4 4 4 0 PhnA Zinc-Ribbon zinc_ribbon_5 PF13719.6 KIY48644.1 - 2.4 8.0 12.1 2.4 8.0 1.8 3.6 3 1 0 3 3 3 0 zinc-ribbon domain zf-IS66 PF13005.7 KIY48644.1 - 2.7 8.5 11.8 10 6.6 0.1 3.8 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 OrfB_Zn_ribbon PF07282.11 KIY48644.1 - 3 7.8 9.0 3 7.8 0.4 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Ogr_Delta PF04606.12 KIY48644.1 - 3.3 7.8 9.1 0.47 10.5 0.9 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-ACC PF17848.1 KIY48644.1 - 4.1 7.6 16.1 4.2 7.5 1.0 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_13 PF09855.9 KIY48644.1 - 5.2 7.3 11.1 15 5.9 0.7 3.1 2 2 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) XAF1_C PF18608.1 KIY48644.1 - 5.5 6.6 11.6 4.2 7.0 0.6 3.8 4 0 0 4 4 4 0 XIAP-associated factor 1 C-terminal domain Pkinase PF00069.25 KIY48646.1 - 8.7e-61 205.6 0.0 3.4e-60 203.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48646.1 - 1.6e-29 103.0 0.1 7.8e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY48646.1 - 0.0003 20.2 0.4 0.016 14.6 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KIY48646.1 - 0.00051 20.0 0.1 0.07 13.0 0.0 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY48646.1 - 0.00077 18.9 0.2 0.014 14.8 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY48646.1 - 0.0032 16.5 0.1 0.0048 15.9 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIY48646.1 - 0.042 13.5 0.2 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family MFS_1 PF07690.16 KIY48649.1 - 1.7e-12 47.0 28.7 1.7e-12 47.0 28.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY48649.1 - 1.7e-11 44.1 6.9 1.7e-11 44.1 6.9 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 APH PF01636.23 KIY48652.1 - 4.3e-16 59.6 0.0 7.5e-16 58.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY48652.1 - 0.00036 20.2 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIY48652.1 - 0.0091 15.6 0.0 0.023 14.3 0.0 1.6 2 0 0 2 2 2 1 RIO1 family DUF4560 PF15118.6 KIY48653.1 - 0.04 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4560) RVT_1 PF00078.27 KIY48654.1 - 3.7e-06 26.6 0.1 6.7e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 KIY48655.1 - 1.2e-05 24.9 0.0 3.8e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fez1 PF06818.15 KIY48655.1 - 1.1 9.7 9.1 0.054 13.9 1.6 2.4 2 0 0 2 2 2 0 Fez1 DUF3552 PF12072.8 KIY48655.1 - 1.3 8.4 13.1 0.013 15.0 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Retrotran_gag_2 PF14223.6 KIY48656.1 - 2.5e-11 43.4 0.2 3.5e-07 30.0 0.0 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIY48656.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) F_actin_bind PF08919.10 KIY48656.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 F-actin binding Retrotran_gag_3 PF14244.6 KIY48656.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.6 KIY48660.1 - 3.6e-07 30.6 0.0 8.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY48660.1 - 0.00012 22.6 0.0 0.00032 21.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIY48660.1 - 0.025 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Aldo_ket_red PF00248.21 KIY48662.1 - 7.8e-71 238.7 0.2 1e-70 238.3 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIY48663.1 - 1e-72 244.9 0.1 1.3e-72 244.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FYRC PF05965.14 KIY48663.1 - 0.0056 16.8 0.1 0.14 12.4 0.0 2.6 3 0 0 3 3 3 1 F/Y rich C-terminus PP2C PF00481.21 KIY48665.1 - 1.9e-71 240.7 0.0 2.3e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C FAM176 PF14851.6 KIY48666.1 - 0.0013 18.4 4.4 2.5 7.8 5.4 2.3 2 0 0 2 2 2 2 FAM176 family CDC45 PF02724.14 KIY48666.1 - 0.0015 16.9 0.2 0.0018 16.7 0.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 KIY48666.1 - 0.12 10.5 5.6 0.16 10.2 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KIY48666.1 - 3.7 6.8 11.5 5.9 6.1 11.5 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KIY48666.1 - 4.4 5.3 12.4 6.2 4.8 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi GATase_5 PF13507.6 KIY48667.1 - 2.5e-100 334.9 0.0 3.9e-100 334.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KIY48667.1 - 2.4e-38 131.7 0.1 1.2e-26 93.7 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KIY48667.1 - 1.6e-33 115.1 0.0 3e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KIY48667.1 - 4.9e-19 68.6 0.0 1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KIY48667.1 - 0.24 12.0 2.2 4 8.2 0.0 2.7 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain TMEM154 PF15102.6 KIY48668.1 - 0.011 15.6 1.3 0.011 15.6 1.3 1.6 1 1 0 1 1 1 0 TMEM154 protein family DUF1179 PF06678.11 KIY48668.1 - 0.18 11.8 0.8 0.3 11.1 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) Claudin_2 PF13903.6 KIY48668.1 - 0.82 9.4 3.1 7.5 6.3 2.1 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.6 KIY48668.1 - 0.91 10.5 3.1 2 9.3 3.1 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Zn_clus PF00172.18 KIY48670.1 - 4e-09 36.5 10.7 9.1e-09 35.3 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.20 KIY48671.1 - 5.7e-95 318.5 0.0 6.5e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family BTB PF00651.31 KIY48672.1 - 0.00018 21.7 0.0 0.00035 20.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HMG_box PF00505.19 KIY48673.1 - 2.2e-08 34.4 0.1 4.8e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY48673.1 - 6.6e-06 26.6 0.4 1.3e-05 25.7 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain Sec2p PF06428.11 KIY48674.1 - 8.9e-09 35.2 12.4 8.9e-09 35.2 12.4 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p zf-C4H2 PF10146.9 KIY48674.1 - 0.0015 18.9 6.7 0.036 14.4 2.7 2.2 1 1 1 2 2 2 2 Zinc finger-containing protein NAP PF00956.18 KIY48674.1 - 0.26 10.4 2.3 0.39 9.9 2.3 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Cpn60_TCP1 PF00118.24 KIY48676.1 - 1.2e-129 433.2 9.8 1.4e-129 432.9 9.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ABC_membrane PF00664.23 KIY48677.1 - 1.9e-46 158.9 35.8 3e-28 99.2 7.3 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 KIY48677.1 - 5.6e-40 137.0 0.9 1.3e-26 93.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY48677.1 - 1.6e-12 47.4 0.9 0.00019 20.9 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY48677.1 - 2.5e-06 28.0 0.2 0.067 13.6 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 KIY48677.1 - 4.9e-06 26.3 0.1 0.1 12.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KIY48677.1 - 2e-05 24.3 0.3 0.053 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KIY48677.1 - 0.00013 21.2 0.2 0.017 14.2 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_23 PF13476.6 KIY48677.1 - 0.00021 21.9 0.0 0.00021 21.9 0.0 2.9 4 0 0 4 4 2 1 AAA domain MMR_HSR1 PF01926.23 KIY48677.1 - 0.0003 20.9 0.1 0.7 10.0 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KIY48677.1 - 0.00045 20.1 1.1 0.061 13.1 0.0 3.4 3 1 1 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KIY48677.1 - 0.0006 20.0 0.1 0.057 13.5 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KIY48677.1 - 0.0025 17.7 0.0 0.64 9.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 KIY48677.1 - 0.0029 17.2 0.3 1.4 8.4 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KIY48677.1 - 0.0035 16.7 0.0 0.45 9.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.29 KIY48677.1 - 0.0037 17.1 0.2 3.7 7.3 0.1 3.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Adeno_IVa2 PF02456.15 KIY48677.1 - 0.0042 15.9 0.0 0.03 13.1 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_22 PF13401.6 KIY48677.1 - 0.018 15.3 0.4 8.6 6.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIY48677.1 - 0.029 14.3 0.2 15 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KIY48677.1 - 0.039 13.9 0.2 0.44 10.4 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIY48677.1 - 0.046 14.2 0.0 2.2 8.7 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KIY48677.1 - 0.075 12.8 0.0 0.65 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIY48677.1 - 0.1 13.1 0.0 11 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KIY48677.1 - 0.11 12.5 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KIY48677.1 - 0.12 12.1 0.4 17 5.0 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KIY48677.1 - 0.17 11.1 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 KIY48677.1 - 0.17 11.3 0.2 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.23 KIY48677.1 - 0.19 11.8 0.6 27 4.8 0.0 2.7 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KIY48677.1 - 0.22 11.7 0.8 47 4.2 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KIY48677.1 - 0.27 10.8 2.7 0.82 9.2 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AA_permease PF00324.21 KIY48678.1 - 3.3e-117 392.0 26.6 3.8e-117 391.8 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY48678.1 - 8e-34 117.2 27.9 1e-33 116.9 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease SpoVAB PF13782.6 KIY48678.1 - 1.1 9.6 7.5 0.67 10.3 1.0 2.6 2 0 0 2 2 2 0 Stage V sporulation protein AB Spore_permease PF03845.13 KIY48678.1 - 1.3 7.8 15.8 0.11 11.3 7.9 2.6 3 0 0 3 3 3 0 Spore germination protein CMAS PF02353.20 KIY48679.1 - 4.2e-10 39.4 0.0 4.9e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TMCCDC2 PF15844.5 KIY48680.1 - 0.096 12.6 1.5 0.18 11.8 1.5 1.3 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 DDE_Tnp_4 PF13359.6 KIY48681.1 - 7.2e-22 77.7 0.0 1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 KIY48682.1 - 1.6e-12 47.4 0.0 4e-05 23.2 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIY48683.1 - 1.5e-08 35.2 2.2 1.5e-08 35.2 2.2 2.3 2 2 1 3 3 3 1 zinc-binding in reverse transcriptase DUF4486 PF14858.6 KIY48683.1 - 0.08 11.4 0.5 0.12 10.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) MMR1 PF08505.10 KIY48683.1 - 0.13 12.5 0.4 0.19 12.0 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein HDV_ag PF01517.18 KIY48688.1 - 0.29 10.9 2.0 0.21 11.3 0.3 1.6 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen LAL_C2 PF18603.1 KIY48692.1 - 0.081 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 KDZ PF18758.1 KIY48693.1 - 6.5e-62 209.1 0.0 1.2e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY48693.1 - 0.028 14.6 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases TTL PF03133.15 KIY48693.1 - 0.082 12.0 1.3 0.16 11.0 1.3 1.4 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family DUF3701 PF12482.8 KIY48693.1 - 0.12 12.5 0.2 6.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Phage integrase protein Clathrin PF00637.20 KIY48693.1 - 0.24 11.3 4.8 0.073 12.9 0.3 2.2 2 1 0 2 2 2 0 Region in Clathrin and VPS FTA4 PF13093.6 KIY48693.1 - 1.1 9.1 16.6 6.5 6.6 0.1 3.7 2 1 1 3 3 3 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ERp29 PF07749.12 KIY48693.1 - 9 7.3 8.4 1.5 9.8 1.7 2.8 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Pkinase PF00069.25 KIY48695.1 - 5.1e-23 81.8 0.0 3e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48695.1 - 1.5e-06 27.7 0.2 0.19 11.0 0.2 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase LRRCT PF01463.24 KIY48702.1 - 0.8 10.4 6.9 38 5.2 0.1 3.8 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain G10 PF01125.17 KIY48702.1 - 3.7 7.3 7.2 4 7.2 0.5 2.3 2 0 0 2 2 2 0 G10 protein zf-CCHC_3 PF13917.6 KIY48704.1 - 0.043 13.8 2.9 0.11 12.5 2.9 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KIY48704.1 - 6.1 6.6 13.6 1.1 9.1 9.6 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger gag-asp_proteas PF13975.6 KIY48705.1 - 7.1e-05 23.3 0.0 0.00022 21.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY48705.1 - 0.076 13.7 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 KIY48705.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Glyco_hydro_88 PF07470.13 KIY48708.1 - 1.9e-14 53.5 0.9 1.9e-14 53.5 0.9 1.4 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Rad60-SLD_2 PF13881.6 KIY48709.1 - 6.8e-14 51.9 0.0 8.2e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIY48709.1 - 2.8e-05 23.8 0.0 0.00034 20.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KIY48709.1 - 0.071 13.7 0.0 0.085 13.4 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Pec_lyase_C PF00544.19 KIY48711.1 - 5e-07 29.5 3.8 7.3e-05 22.5 0.5 2.3 1 1 1 2 2 2 2 Pectate lyase FHA PF00498.26 KIY48713.1 - 3.5e-10 40.1 0.0 5.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIY48713.1 - 0.00033 20.9 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain IPPT PF01715.17 KIY48715.1 - 1.6e-59 201.5 0.1 3e-59 200.6 0.1 1.4 1 1 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 KIY48715.1 - 0.0008 19.6 0.1 0.01 16.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIY48715.1 - 0.033 14.7 0.1 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIY48715.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KIY48715.1 - 0.13 12.6 0.0 0.46 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 KIY48716.1 - 5.7e-14 53.1 0.0 9.7e-14 52.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FMN_red PF03358.15 KIY48717.1 - 5.8e-10 39.1 0.0 1.3e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIY48717.1 - 8.3e-05 22.4 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KIY48717.1 - 0.0033 17.7 0.0 0.0091 16.2 0.0 1.9 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KIY48717.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Fungal_trans PF04082.18 KIY48718.1 - 6.2e-24 84.5 0.3 1.6e-23 83.1 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_18 PF00704.28 KIY48719.1 - 7.5e-44 150.7 0.0 1e-43 150.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_1 PF00232.18 KIY48719.1 - 0.18 10.1 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 KDZ PF18758.1 KIY48721.1 - 5.5e-41 140.6 0.0 8.4e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase FTA4 PF13093.6 KIY48721.1 - 0.46 10.3 5.6 8.7 6.2 0.1 2.1 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 KDZ PF18758.1 KIY48722.1 - 5.6e-25 88.3 0.0 7.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY48722.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Mito_fiss_reg PF05308.11 KIY48723.1 - 0.073 13.1 3.3 0.09 12.9 3.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KIY48723.1 - 1 8.8 10.4 1.2 8.5 10.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SapB_2 PF03489.17 KIY48728.1 - 0.069 13.3 1.0 9.2 6.5 0.0 2.6 3 0 0 3 3 3 0 Saposin-like type B, region 2 Cep57_CLD PF14073.6 KIY48729.1 - 0.027 14.5 3.3 0.036 14.1 3.3 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 cwf18 PF08315.12 KIY48730.1 - 0.98 10.1 6.7 1.6 9.4 6.7 1.3 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor TetR_C_19 PF17924.1 KIY48732.1 - 0.0081 16.7 0.1 2.9 8.5 0.0 2.5 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain Plavaka PF18759.1 KIY48733.1 - 1.9e-23 83.2 1.9 2.7e-23 82.7 1.9 1.1 1 0 0 1 1 1 1 Plavaka transposase Kdo PF06293.14 KIY48739.1 - 1.3e-10 41.0 0.0 2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIY48739.1 - 3.7e-06 26.5 0.0 4.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIY48739.1 - 5.1e-06 26.6 0.1 1.8e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KIY48739.1 - 7.7e-05 22.2 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KIY48739.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KIY48739.1 - 0.052 12.3 0.1 0.062 12.1 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KIY48739.1 - 0.097 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase PRKCSH-like PF12999.7 KIY48740.1 - 6.2e-48 162.9 1.1 1.5e-47 161.7 1.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KIY48740.1 - 2.3e-29 102.0 0.1 4e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KIY48740.1 - 8.3e-11 42.7 0.9 8.3e-11 42.7 0.9 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein OmpH PF03938.14 KIY48740.1 - 0.18 12.1 8.6 6 7.2 3.7 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 KIY48740.1 - 5.7 5.3 7.3 8.5 4.8 7.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ERG2_Sigma1R PF04622.12 KIY48741.1 - 4.9e-87 290.7 0.0 1.1e-86 289.5 0.0 1.5 1 1 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Ribosomal_S25 PF03297.15 KIY48742.1 - 1.2e-36 125.0 2.2 1.2e-36 124.9 2.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 KIY48742.1 - 0.0018 17.8 0.1 0.0029 17.1 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIY48742.1 - 0.034 14.1 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 MarR family PaaX PF07848.12 KIY48742.1 - 0.043 14.0 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein F-box-like PF12937.7 KIY48743.1 - 1.9e-05 24.4 0.7 1.9e-05 24.4 0.7 2.2 2 0 0 2 2 2 1 F-box-like DUF1724 PF08350.10 KIY48744.1 - 0.17 12.0 0.0 17 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1724) Retrotrans_gag PF03732.17 KIY48745.1 - 0.00033 20.9 0.2 0.00069 19.8 0.1 1.7 1 1 1 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 KIY48746.1 - 5.4e-07 30.1 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KIY48746.1 - 4.3e-06 26.5 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIY48746.1 - 5.9e-06 26.8 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIY48746.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 KIY48746.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF3960 PF13142.6 KIY48748.1 - 0.041 14.0 0.0 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3960) PAPA-1 PF04795.12 KIY48748.1 - 0.067 14.0 0.4 2.8 8.8 0.1 2.3 1 1 1 2 2 2 0 PAPA-1-like conserved region Plavaka PF18759.1 KIY48749.1 - 7.6e-60 202.8 0.3 8.4e-60 202.7 0.3 1.0 1 0 0 1 1 1 1 Plavaka transposase Co_AT_N PF12557.8 KIY48749.1 - 0.025 14.5 1.0 0.052 13.5 1.0 1.5 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Plavaka PF18759.1 KIY48750.1 - 1.3e-19 70.6 0.2 1.7e-19 70.2 0.2 1.1 1 0 0 1 1 1 1 Plavaka transposase ketoacyl-synt PF00109.26 KIY48751.1 - 8e-18 64.9 0.2 9.4e-18 64.7 0.2 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KIY48751.1 - 0.027 13.9 1.3 0.06 12.7 0.2 1.9 2 1 0 2 2 2 0 Thiolase, N-terminal domain Fas_alpha_ACP PF18325.1 KIY48752.1 - 1.2e-71 240.3 0.0 1.8e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KIY48752.1 - 3.8e-10 39.7 0.2 7.2e-10 38.8 0.2 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 KIY48753.1 - 1.5e-58 198.8 0.0 1.8e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain Peptidase_Prp PF04327.12 KIY48753.1 - 0.11 12.8 0.3 0.25 11.6 0.3 1.6 1 0 0 1 1 1 0 Cysteine protease Prp Lipase_3 PF01764.25 KIY48753.1 - 0.16 11.9 0.3 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Tet_JBP PF12851.7 KIY48754.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily PUF PF00806.19 KIY48757.1 - 6.7e-11 41.3 0.0 0.25 11.1 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat B12D PF06522.11 KIY48758.1 - 5.8e-15 54.9 0.2 7.2e-15 54.6 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit B12D PF06522.11 KIY48759.1 - 1.3e-08 34.4 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit malic PF00390.19 KIY48760.1 - 5e-33 114.4 0.0 1.1e-32 113.3 0.0 1.5 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 KIY48760.1 - 3.8e-27 95.2 0.1 1.1e-23 83.8 0.1 3.5 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain dsrm PF00035.26 KIY48761.1 - 1.9e-06 28.5 0.0 2.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Stathmin PF00836.19 KIY48762.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Stathmin family DDE_3 PF13358.6 KIY48763.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF1593 PF07632.11 KIY48763.1 - 0.058 12.8 0.0 0.083 12.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1593) Metallopep PF12044.8 KIY48765.1 - 2e-29 102.5 0.0 2.2e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Pox_P4B PF03292.14 KIY48765.1 - 0.27 9.5 0.0 0.32 9.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Metallopep PF12044.8 KIY48766.1 - 7.4e-22 77.5 0.0 9.6e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family DDE_1 PF03184.19 KIY48767.1 - 2.4e-18 66.4 0.0 3.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_18 PF13238.6 KIY48767.1 - 0.16 12.5 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 KIY48768.1 - 3.1e-09 36.6 2.0 1e-08 34.9 2.0 2.0 1 0 0 1 1 1 1 F-box-like NAC PF01849.18 KIY48768.1 - 0.23 11.4 0.0 0.43 10.6 0.0 1.3 1 0 0 1 1 1 0 NAC domain HAD_2 PF13419.6 KIY48769.1 - 9e-15 55.2 0.0 1.3e-13 51.4 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY48769.1 - 3.4e-10 40.5 0.0 0.00026 21.4 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY48769.1 - 6.1e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIY48769.1 - 0.04 14.3 0.3 0.085 13.3 0.2 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIY48769.1 - 0.044 13.9 0.0 1.1 9.4 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NAD_Gly3P_dh_N PF01210.23 KIY48770.1 - 2e-41 141.6 0.0 3.1e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KIY48770.1 - 3.1e-39 134.5 0.0 4.3e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KIY48770.1 - 5.7e-06 26.8 0.0 1.5e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KIY48770.1 - 0.011 15.6 0.6 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 Rossmann-like domain Cu_bind_CorA PF18252.1 KIY48770.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Copper(I)-binding protein CorA NapD PF03927.13 KIY48770.1 - 0.19 11.8 0.1 0.53 10.4 0.1 1.7 1 0 0 1 1 1 0 NapD protein Sel1 PF08238.12 KIY48771.1 - 2.9e-15 56.4 6.7 0.0026 18.4 0.0 7.7 8 0 0 8 8 8 3 Sel1 repeat TPR_7 PF13176.6 KIY48771.1 - 0.036 14.1 0.1 0.13 12.4 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY48771.1 - 0.045 14.0 0.1 2.6 8.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY48771.1 - 0.046 13.5 0.1 0.46 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY48771.1 - 0.051 13.7 3.4 0.063 13.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY48771.1 - 0.27 12.0 1.4 4 8.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY48771.1 - 2.2 9.3 4.9 1.7 9.7 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Amidohydro_3 PF07969.11 KIY48772.1 - 4.2e-15 56.2 2.5 1.5e-09 37.8 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIY48772.1 - 1e-14 54.6 0.0 1.1e-11 44.7 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family DDE_1 PF03184.19 KIY48774.1 - 2.2e-40 138.2 0.0 3.5e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KIY48774.1 - 3.5e-06 27.0 0.1 9.7e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Methyltransf_16 PF10294.9 KIY48775.1 - 2.6e-12 46.8 0.0 3.3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIY48775.1 - 0.0019 18.0 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY48775.1 - 0.0056 17.4 0.0 0.011 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF1295 PF06966.12 KIY48776.1 - 3.6e-20 72.5 0.1 4.6e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KIY48776.1 - 3.5e-09 37.0 0.0 9.5e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 KIY48776.1 - 2.7e-08 33.6 0.8 3.9e-08 33.0 0.8 1.3 1 0 0 1 1 1 1 NnrU protein ICMT PF04140.14 KIY48776.1 - 1.5e-06 28.5 0.0 3.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KIY48776.1 - 3.7e-06 27.0 0.0 7.3e-06 26.0 0.0 1.6 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 KIY48776.1 - 2.4e-05 23.3 0.1 8e-05 21.6 0.1 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Kinesin PF00225.23 KIY48777.1 - 4.2e-90 302.0 0.0 5.5e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY48777.1 - 1.3e-18 67.3 0.0 2.6e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Torus PF16131.5 KIY48778.1 - 6.4e-10 39.7 4.5 0.00057 20.6 0.3 2.8 2 1 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 KIY48778.1 - 9e-09 34.9 9.1 5e-05 23.0 1.4 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KIY48778.1 - 3.3e-05 23.7 7.0 0.0007 19.4 1.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY48778.1 - 0.00037 20.5 2.5 0.00037 20.5 2.5 2.7 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 KIY48778.1 - 0.001 19.2 0.6 0.0019 18.4 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger containing family DUF4266 PF14086.6 KIY48778.1 - 0.055 14.4 1.6 0.15 13.0 1.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) DUF3464 PF11947.8 KIY48778.1 - 0.3 10.8 1.3 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 GST_N_3 PF13417.6 KIY48779.1 - 5.3e-18 65.2 0.0 9.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY48779.1 - 2.1e-16 60.0 0.0 4.3e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY48779.1 - 6.2e-15 55.3 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KIY48779.1 - 0.00012 22.2 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 KIY48779.1 - 0.0026 17.7 0.1 0.0049 16.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Transp_cyt_pur PF02133.15 KIY48780.1 - 4.3e-35 121.3 32.3 7e-34 117.3 32.3 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bunya_G2 PF03563.13 KIY48780.1 - 0.049 12.9 1.3 0.084 12.1 1.3 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Abhydrolase_3 PF07859.13 KIY48781.1 - 2.6e-60 203.9 0.0 3.1e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY48781.1 - 9.6e-11 41.2 1.8 1.4e-09 37.3 1.0 2.6 1 1 1 2 2 2 1 Carboxylesterase family Say1_Mug180 PF10340.9 KIY48781.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.5 1 1 0 1 1 1 0 Steryl acetyl hydrolase HgmA PF04209.13 KIY48782.1 - 6.5e-158 525.9 0.1 7.6e-158 525.7 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Usp PF00582.26 KIY48783.1 - 1.3e-12 48.4 0.1 5.2e-12 46.5 0.1 1.9 1 1 0 1 1 1 1 Universal stress protein family Spt20 PF12090.8 KIY48784.1 - 0.0078 15.9 5.5 0.0082 15.8 5.5 1.1 1 0 0 1 1 1 1 Spt20 family DUF247 PF03140.15 KIY48784.1 - 0.015 14.5 0.0 0.016 14.4 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function DUF4647 PF15504.6 KIY48784.1 - 0.023 13.8 2.5 0.025 13.7 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) S36_mt PF10937.8 KIY48784.1 - 0.1 14.2 3.1 0.14 13.8 3.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial SUIM_assoc PF16619.5 KIY48784.1 - 0.22 11.6 9.8 0.65 10.1 9.8 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Lipase_3 PF01764.25 KIY48785.1 - 6.7e-24 84.4 0.0 1.1e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY48785.1 - 4.4e-05 24.2 2.2 6.7e-05 23.6 1.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY48785.1 - 0.0002 20.7 0.2 0.00039 19.8 0.1 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KIY48785.1 - 0.0041 16.9 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KIY48785.1 - 0.014 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PE-PPE PF08237.11 KIY48785.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Pro_CA PF00484.19 KIY48785.1 - 0.033 14.5 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 Carbonic anhydrase Abhydrolase_1 PF00561.20 KIY48785.1 - 0.092 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KIY48785.1 - 0.1 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KIY48785.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.25 KIY48786.1 - 1.2e-66 224.8 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48786.1 - 1.1e-31 110.1 0.0 3.7e-31 108.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY48786.1 - 0.00066 19.1 0.2 0.0011 18.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY48786.1 - 0.0032 16.5 0.1 0.0045 16.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY48786.1 - 0.004 16.5 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Phage_sheath_1C PF17482.2 KIY48786.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 Phage tail sheath C-terminal domain APH PF01636.23 KIY48786.1 - 0.031 14.2 1.2 0.18 11.7 0.7 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family APH PF01636.23 KIY48787.1 - 4e-18 66.2 0.0 1.3e-17 64.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIY48787.1 - 0.00041 19.3 0.0 0.21 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.14 KIY48787.1 - 0.071 12.4 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KIY48787.1 - 0.089 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Ecdysteroid kinase DUF5302 PF17227.2 KIY48788.1 - 1.9 9.5 0.0 1.9 9.5 0.0 2.9 4 0 0 4 4 4 0 Family of unknown function (DUF5302) DUF485 PF04341.12 KIY48789.1 - 0.4 10.7 0.1 0.4 10.7 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function, DUF485 p450 PF00067.22 KIY48790.1 - 1e-62 212.4 0.0 3.5e-62 210.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 XPG_N PF00752.17 KIY48791.1 - 2.9e-25 88.7 0.0 1e-24 86.9 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KIY48791.1 - 1.6e-21 76.5 0.0 2.9e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KIY48791.1 - 2e-08 34.0 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KIY48791.1 - 4.6e-06 27.1 0.0 9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.28 KIY48791.1 - 0.005 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat HHH_5 PF14520.6 KIY48791.1 - 0.0061 17.1 0.0 0.021 15.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain TPR_2 PF07719.17 KIY48791.1 - 0.0091 16.0 0.3 0.023 14.8 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY48791.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HHH_2 PF12826.7 KIY48791.1 - 0.052 13.7 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif TPR_12 PF13424.6 KIY48791.1 - 0.059 13.7 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY48791.1 - 0.1 13.3 1.1 0.28 11.9 1.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DSPc PF00782.20 KIY48793.1 - 1.4e-25 89.6 0.0 2e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY48793.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIY48793.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 KIY48793.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PPR_2 PF13041.6 KIY48794.1 - 4.7e-05 23.5 0.0 0.27 11.5 0.0 3.6 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 KIY48794.1 - 0.12 12.5 0.0 2.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain RabGAP-TBC PF00566.18 KIY48795.1 - 1.4e-20 73.8 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ANAPC4_WD40 PF12894.7 KIY48796.1 - 0.0061 16.8 0.0 1.6 9.0 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY48796.1 - 0.015 16.1 7.2 32 5.6 0.0 5.5 5 1 0 5 5 5 0 WD domain, G-beta repeat TraK PF06586.11 KIY48796.1 - 0.031 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 TraK protein Mcp5_PH PF12814.7 KIY48797.1 - 2.1e-45 153.7 0.0 3.7e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KIY48797.1 - 2e-05 25.0 0.0 3.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PH domain Filament PF00038.21 KIY48797.1 - 0.001 18.7 14.7 0.001 18.7 14.7 2.9 3 0 0 3 3 3 1 Intermediate filament protein KASH_CCD PF14662.6 KIY48797.1 - 0.002 18.0 12.7 0.002 18.0 12.7 3.0 3 0 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 KIY48797.1 - 0.28 10.4 23.1 0.21 10.8 0.4 3.9 3 1 1 4 4 4 0 HAP1 N-terminal conserved region Rx_N PF18052.1 KIY48797.1 - 0.45 10.8 6.9 2.4 8.5 6.9 2.3 1 1 0 1 1 1 0 Rx N-terminal domain Golgin_A5 PF09787.9 KIY48797.1 - 4 6.8 28.3 0.094 12.2 15.6 3.1 3 0 0 3 3 3 0 Golgin subfamily A member 5 ADH_zinc_N PF00107.26 KIY48798.1 - 1.5e-28 99.3 1.0 2.5e-28 98.7 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY48798.1 - 7.7e-17 62.6 0.0 1.8e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY48798.1 - 4.1e-10 39.5 0.0 1.2e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KIY48798.1 - 0.00041 20.6 0.0 0.00088 19.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KIY48798.1 - 0.015 14.6 0.9 0.022 14.1 0.9 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.6 KIY48798.1 - 0.044 13.8 0.1 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 SIS domain Aminotran_1_2 PF00155.21 KIY48798.1 - 0.098 11.8 0.2 2.2 7.4 0.1 2.3 2 1 0 2 2 2 0 Aminotransferase class I and II rRNA_methylase PF06962.12 KIY48798.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative rRNA methylase FAD_binding_3 PF01494.19 KIY48801.1 - 5.6e-20 71.9 0.1 1.7e-19 70.3 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY48801.1 - 7.2e-09 35.3 0.2 0.0034 16.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY48801.1 - 3e-07 29.9 0.3 1e-05 24.9 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 KIY48801.1 - 3.7e-07 30.1 0.5 0.0055 16.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIY48801.1 - 1.3e-05 24.8 0.1 4.2e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY48801.1 - 0.00038 19.3 0.2 0.13 11.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KIY48801.1 - 0.00047 20.3 0.1 0.0012 19.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY48801.1 - 0.00079 18.8 0.0 0.065 12.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY48801.1 - 0.0019 18.7 0.0 0.21 12.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY48801.1 - 0.0047 15.8 0.1 0.76 8.6 0.0 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KIY48801.1 - 0.0071 15.4 1.9 0.17 10.9 0.1 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein PTS_EIIB PF00367.20 KIY48801.1 - 0.018 14.5 0.5 0.035 13.6 0.0 1.6 2 0 0 2 2 2 0 phosphotransferase system, EIIB GIDA PF01134.22 KIY48801.1 - 0.04 13.0 0.3 0.73 8.8 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 KIY48802.1 - 6.2e-07 28.7 13.6 8.3e-07 28.2 13.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily IBR PF01485.21 KIY48804.1 - 1.5e-09 37.9 44.9 7e-06 26.2 9.6 3.9 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KIY48804.1 - 0.011 15.6 0.7 0.011 15.6 0.7 4.7 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY48804.1 - 0.014 15.4 1.3 0.014 15.4 1.3 4.4 3 1 0 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.6 KIY48804.1 - 0.054 13.8 2.3 0.054 13.8 2.3 4.4 2 1 2 4 4 4 0 Ring finger domain Alpha-amylase PF00128.24 KIY48805.1 - 8.2e-51 173.5 1.7 1.2e-50 173.0 1.7 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIY48805.1 - 3.2e-09 36.9 0.2 6.9e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) GHL10 PF02638.15 KIY48805.1 - 0.0019 17.4 0.2 0.0031 16.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 SKG6 PF08693.10 KIY48806.1 - 0.0021 17.4 0.1 0.0067 15.8 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gly-zipper_Omp PF13488.6 KIY48806.1 - 0.045 13.8 6.0 0.11 12.5 6.0 1.7 1 0 0 1 1 1 0 Glycine zipper DUF2207 PF09972.9 KIY48806.1 - 0.048 12.4 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) IBR PF01485.21 KIY48807.1 - 9.3e-13 48.2 46.1 3.1e-07 30.5 4.4 4.4 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KIY48807.1 - 0.00065 19.6 3.0 0.00065 19.6 3.0 4.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY48807.1 - 0.028 14.8 5.0 0.028 14.8 5.0 5.4 5 1 0 5 5 5 0 Ring finger domain RRXRR PF14239.6 KIY48808.1 - 0.038 13.8 2.1 0.066 13.1 2.1 1.4 1 0 0 1 1 1 0 RRXRR protein WAC_Acf1_DNA_bd PF10537.9 KIY48808.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.4 1 1 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal OPT PF03169.15 KIY48809.1 - 1.7e-165 552.1 53.8 2e-165 551.9 53.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MAD PF05557.13 KIY48810.1 - 0.00024 19.6 5.0 0.00033 19.2 5.0 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Exonuc_VII_L PF02601.15 KIY48810.1 - 0.059 12.9 6.8 0.1 12.2 6.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UVR PF02151.19 KIY48810.1 - 0.15 11.9 4.2 0.096 12.5 1.0 2.3 2 0 0 2 2 2 0 UvrB/uvrC motif zf-RING_UBOX PF13445.6 KIY48810.1 - 0.28 11.3 2.0 0.81 9.8 2.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger FAD_binding_3 PF01494.19 KIY48814.1 - 2.2e-20 73.2 0.1 6.4e-20 71.7 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY48814.1 - 1e-07 31.5 0.4 0.0036 16.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY48814.1 - 1.2e-05 25.1 2.7 0.028 14.0 0.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY48814.1 - 2.6e-05 23.5 0.5 5.8e-05 22.3 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIY48814.1 - 0.00015 21.3 1.4 0.00024 20.6 0.7 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY48814.1 - 0.00046 20.4 0.6 0.0012 19.0 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY48814.1 - 0.001 19.6 0.1 0.043 14.4 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY48814.1 - 0.0013 18.0 0.0 0.024 13.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY48814.1 - 0.0014 17.4 0.7 0.18 10.5 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.14 KIY48814.1 - 0.0018 17.2 0.8 0.45 9.3 0.1 2.7 3 0 0 3 3 3 2 Tryptophan halogenase PTS_EIIB PF00367.20 KIY48814.1 - 0.036 13.6 0.0 0.036 13.6 0.0 1.8 3 0 0 3 3 3 0 phosphotransferase system, EIIB Lycopene_cycl PF05834.12 KIY48814.1 - 0.17 10.9 3.8 0.28 10.2 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 KIY48814.1 - 0.21 10.6 0.9 1.2 8.2 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A APH PF01636.23 KIY48815.1 - 2.2e-07 31.0 0.1 3.2e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY48815.1 - 0.00018 21.0 0.2 0.037 13.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY48815.1 - 0.09 12.0 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.14 KIY48815.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase LXG PF04740.12 KIY48816.1 - 0.052 13.2 2.9 0.39 10.4 2.5 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily HsbA PF12296.8 KIY48816.1 - 0.086 13.3 10.4 0.038 14.4 8.1 1.7 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Gemini_AC4_5_2 PF08464.10 KIY48816.1 - 0.14 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Cauli_DNA-bind PF03310.13 KIY48816.1 - 0.16 12.0 0.8 0.3 11.2 0.4 1.6 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein EF-G-binding_N PF07299.11 KIY48816.1 - 0.17 12.4 0.9 0.52 10.9 0.6 1.8 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal F-box-like PF12937.7 KIY48824.1 - 3.4e-07 30.1 2.5 7.4e-07 29.0 0.2 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY48824.1 - 0.081 13.4 0.0 24 5.5 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Cid2 PF09774.9 KIY48826.1 - 5.1e-26 92.0 7.7 8.6e-26 91.3 7.7 1.3 1 0 0 1 1 1 1 Caffeine-induced death protein 2 GPP34 PF05719.11 KIY48826.1 - 0.063 13.3 0.7 0.11 12.5 0.7 1.5 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) CM_2 PF01817.21 KIY48826.1 - 0.12 12.7 1.8 0.19 12.1 0.1 2.1 2 1 0 2 2 2 0 Chorismate mutase type II Med2 PF11214.8 KIY48827.1 - 0.2 11.8 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 2 Retrotran_gag_2 PF14223.6 KIY48829.1 - 4e-07 29.8 0.1 5.2e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIY48829.1 - 0.035 13.9 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Rnk_N PF14760.6 KIY48830.1 - 0.088 13.3 0.1 0.088 13.3 0.1 2.0 3 0 0 3 3 3 0 Rnk N-terminus DUF5512 PF17631.2 KIY48831.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5512) V-ATPase_G PF03179.15 KIY48831.1 - 0.097 13.2 0.1 0.16 12.6 0.1 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Transposase_21 PF02992.14 KIY48833.1 - 0.00043 19.6 0.1 0.0023 17.2 0.0 2.1 3 0 0 3 3 3 1 Transposase family tnp2 Transposase_21 PF02992.14 KIY48834.1 - 0.02 14.2 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Transposase family tnp2 Dynamin_M PF01031.20 KIY48836.1 - 1.1e-27 97.0 0.3 2.8e-18 66.1 0.0 2.8 2 1 1 3 3 3 2 Dynamin central region Dynamin_N PF00350.23 KIY48836.1 - 6.7e-26 91.3 0.0 1.4e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIY48836.1 - 3.3e-13 49.6 0.1 9.7e-13 48.1 0.1 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY48836.1 - 6.2e-05 23.1 0.0 0.0042 17.1 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY48836.1 - 0.003 18.0 0.8 0.39 11.1 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 KIY48836.1 - 0.018 15.5 0.2 0.15 12.6 0.0 2.5 3 0 0 3 3 3 0 ABC transporter DUF1542 PF07564.11 KIY48836.1 - 0.027 14.6 0.9 5.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) AAA_29 PF13555.6 KIY48836.1 - 0.04 13.7 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 KIY48836.1 - 0.068 12.7 0.1 6.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B OGFr_N PF04664.13 KIY48836.1 - 0.069 12.7 1.4 0.87 9.1 1.4 2.2 1 1 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region AAA_21 PF13304.6 KIY48836.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SGL PF08450.12 KIY48838.1 - 1.7e-27 96.6 0.1 2.9e-27 95.8 0.1 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KIY48838.1 - 0.00045 20.4 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.16 KIY48838.1 - 0.0007 19.7 0.0 0.0026 17.9 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Kelch_3 PF13415.6 KIY48838.1 - 0.079 13.3 0.4 5.1 7.5 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain GST_N_3 PF13417.6 KIY48839.1 - 2.4e-18 66.3 0.1 4e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY48839.1 - 4e-14 52.7 0.0 6.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY48839.1 - 5.1e-05 23.5 0.1 7.8e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KIY48839.1 - 0.018 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin CDC27 PF09507.10 KIY48840.1 - 4.5 6.6 24.4 0.32 10.3 16.0 2.2 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 adh_short_C2 PF13561.6 KIY48842.1 - 1.2e-54 185.4 1.6 1.4e-54 185.2 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY48842.1 - 9.4e-48 162.3 0.8 1.2e-47 161.9 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY48842.1 - 1.5e-14 54.3 0.5 2e-14 53.9 0.5 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY48842.1 - 0.013 14.9 0.0 0.28 10.5 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KIY48842.1 - 0.022 14.1 0.2 0.046 13.0 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.6 KIY48843.1 - 4.1e-27 95.2 0.0 4.7e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY48843.1 - 9.9e-27 93.7 0.0 1.1e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY48843.1 - 0.0073 16.2 0.0 0.0092 15.9 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY48843.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.6 KIY48844.1 - 3.4e-55 187.1 1.4 3.9e-55 186.9 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY48844.1 - 4.4e-49 166.6 0.5 5.8e-49 166.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY48844.1 - 3.8e-15 56.3 0.5 5.3e-15 55.8 0.5 1.1 1 0 0 1 1 1 1 KR domain PRR22 PF15776.5 KIY48844.1 - 0.022 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Proline-rich protein family 22 DUF1776 PF08643.10 KIY48844.1 - 0.055 12.8 0.0 0.25 10.7 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KIY48844.1 - 0.061 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.6 KIY48845.1 - 1.2e-56 191.9 1.0 1.4e-56 191.7 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY48845.1 - 5.3e-50 169.6 0.3 6.7e-50 169.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY48845.1 - 1.4e-15 57.7 0.2 2e-15 57.1 0.2 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIY48845.1 - 0.036 13.4 0.2 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KIY48845.1 - 0.039 13.3 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIY48845.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1992 PF09350.10 KIY48846.1 - 5.4e-18 64.9 0.7 1.2e-17 63.8 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) SGL PF08450.12 KIY48847.1 - 7.5e-30 104.3 0.0 1.2e-29 103.6 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIY48847.1 - 7.3e-05 22.8 0.0 0.00027 21.0 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KIY48847.1 - 0.00067 19.8 0.2 0.0026 17.9 0.0 2.1 2 0 0 2 2 2 1 Arylesterase Pro_isomerase PF00160.21 KIY48848.1 - 5.3e-37 127.5 0.0 8.4e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KIY48848.1 - 8.9e-16 57.5 0.0 1.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_anti-like PF12869.7 KIY48851.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like Uma2 PF05685.12 KIY48851.1 - 0.046 13.2 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative restriction endonuclease Plavaka PF18759.1 KIY48855.1 - 1.1e-112 376.5 0.2 2.4e-111 372.1 0.2 1.9 2 0 0 2 2 2 2 Plavaka transposase DLH PF01738.18 KIY48856.1 - 1.8e-20 73.4 0.0 2.1e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family F-box-like PF12937.7 KIY48857.1 - 9.8e-06 25.4 0.0 2.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY48857.1 - 0.00091 19.0 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain HYLS1_C PF15311.6 KIY48857.1 - 0.12 13.1 0.0 0.26 12.1 0.0 1.5 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus UQ_con PF00179.26 KIY48858.1 - 1.3e-16 60.5 0.0 1.6e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIY48858.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KIY48858.1 - 0.082 13.2 0.0 0.094 13.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain Thiolase_N PF00108.23 KIY48859.1 - 2e-80 269.9 4.6 4.7e-80 268.7 3.5 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY48859.1 - 3.6e-42 142.9 0.1 7.1e-42 141.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIY48859.1 - 0.00049 19.8 1.8 0.0037 16.9 0.8 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Alpha-amylase PF00128.24 KIY48860.1 - 4.1e-20 72.6 0.0 3.2e-19 69.7 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIY48860.1 - 1.7e-09 38.0 0.0 5.2e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain HTH_30 PF13556.6 KIY48862.1 - 0.018 14.9 0.5 0.08 12.8 0.2 2.3 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain p450 PF00067.22 KIY48863.1 - 5.9e-65 219.8 0.0 1.2e-64 218.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KIY48864.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY48864.1 - 7.5e-08 32.5 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY48864.1 - 0.00024 20.6 0.0 0.0024 17.4 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIY48864.1 - 0.0056 15.8 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIY48864.1 - 0.0056 16.1 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KIY48864.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 KIY48866.1 - 2.8e-73 247.2 0.0 5.9e-73 246.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY48867.1 - 3.4e-25 88.7 0.0 4.3e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rer1 PF03248.13 KIY48867.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Rer1 family COesterase PF00135.28 KIY48869.1 - 1.3e-102 344.4 0.0 2.1e-102 343.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY48869.1 - 0.00076 19.4 0.0 0.0047 16.8 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold F-box-like PF12937.7 KIY48870.1 - 0.0035 17.2 0.7 0.012 15.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like Fic_N PF13784.6 KIY48873.1 - 0.052 13.6 0.6 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 Fic/DOC family N-terminal Aldo_ket_red PF00248.21 KIY48875.1 - 5.3e-45 153.9 0.0 1.2e-43 149.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_15 PF00723.21 KIY48876.1 - 5.1e-83 279.3 1.3 6.3e-83 279.0 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KIY48876.1 - 8.5e-29 99.3 0.1 1.7e-28 98.4 0.1 1.5 1 0 0 1 1 1 1 Starch binding domain Glyco_hydro_10 PF00331.20 KIY48877.1 - 1e-98 330.4 0.0 1.2e-98 330.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Corona_NS8 PF12093.8 KIY48877.1 - 0.087 13.4 0.0 1.5 9.4 0.0 2.2 1 1 1 2 2 2 0 Coronavirus NS8 protein zf_C2H2_13 PF18508.1 KIY48878.1 - 0.12 12.0 2.1 0.61 9.7 0.3 2.3 2 0 0 2 2 2 0 Zinc finger domain CDRN PF05174.12 KIY48878.1 - 8.8 6.1 7.0 18 5.1 0.7 2.5 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus Pheromone PF08015.11 KIY48880.1 - 2.9e-05 25.0 10.2 1.5 9.9 2.2 3.8 3 2 0 3 3 3 3 Fungal mating-type pheromone Kinesin PF00225.23 KIY48881.1 - 1.4e-100 336.5 0.0 1.9e-100 336.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY48881.1 - 2.3e-56 189.9 0.0 4.7e-56 188.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Ham1p_like PF01725.16 KIY48881.1 - 0.0025 17.7 0.0 0.0074 16.2 0.0 1.8 1 0 0 1 1 1 1 Ham1 family Spc29 PF17082.5 KIY48881.1 - 0.23 11.3 5.0 0.62 9.9 4.9 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 BRE1 PF08647.11 KIY48881.1 - 0.24 11.5 12.5 0.37 10.9 2.2 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Fzo_mitofusin PF04799.13 KIY48881.1 - 0.28 10.7 2.4 0.92 9.0 2.4 1.9 1 0 0 1 1 1 0 fzo-like conserved region FtsK_SpoIIIE PF01580.18 KIY48881.1 - 0.35 10.2 4.5 1.5 8.1 3.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family p450 PF00067.22 KIY48882.1 - 1.8e-16 60.0 1.8 1.4e-14 53.7 0.2 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KIY48883.1 - 2.8e-65 220.9 0.2 4.3e-63 213.7 0.0 2.4 1 1 0 2 2 2 2 Cytochrome P450 PurA PF04845.13 KIY48883.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein GATA PF00320.27 KIY48884.1 - 3e-07 29.9 7.5 5.3e-07 29.1 7.5 1.4 1 0 0 1 1 1 1 GATA zinc finger Arylsulfotran_2 PF14269.6 KIY48885.1 - 2.6e-45 155.1 0.1 4.9e-45 154.2 0.1 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY48885.1 - 5.5e-17 61.7 0.3 7.1e-16 58.1 0.3 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) ABC_tran PF00005.27 KIY48887.1 - 0.03 14.8 0.0 0.041 14.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter p450 PF00067.22 KIY48888.1 - 2.2e-64 217.9 0.0 2.7e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tcp11 PF05794.13 KIY48889.1 - 2.3e-05 23.7 0.0 3.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 11 p450 PF00067.22 KIY48899.1 - 1.1e-65 222.2 0.0 2.4e-65 221.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KIY48900.1 - 4.5e-07 29.1 0.4 4.5e-07 29.1 0.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily HTH_35 PF13693.6 KIY48901.1 - 0.058 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding LRR_5 PF13306.6 KIY48902.1 - 0.099 12.6 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Dynamin_M PF01031.20 KIY48903.1 - 1.6e-26 93.2 0.0 2.5e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIY48903.1 - 4e-14 53.0 0.0 1.4e-13 51.3 0.0 1.8 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KIY48903.1 - 3.9e-08 33.3 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY48903.1 - 0.00069 19.7 0.0 0.0031 17.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY48903.1 - 0.0031 17.9 0.2 0.93 9.9 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 KIY48903.1 - 0.093 13.0 2.4 3.3 7.9 0.4 3.1 3 0 0 3 3 3 0 AAA domain Pheromone PF08015.11 KIY48904.1 - 1.2e-05 26.2 7.7 2e-05 25.6 7.7 1.3 1 0 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.15 KIY48905.1 - 2.2e-104 348.8 23.1 2.5e-104 348.6 23.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor N-glycanase_N PF09112.10 KIY48905.1 - 0.049 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal Corona_NS4 PF03905.13 KIY48905.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 Coronavirus non-structural protein NS4 SH3BGR PF04908.15 KIY48907.1 - 1.3e-08 34.9 0.1 4.3e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KIY48907.1 - 0.083 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Isochorismatase PF00857.20 KIY48912.1 - 1.4e-18 67.7 0.0 1.1e-17 64.8 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family Ntox27 PF15531.6 KIY48912.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 27 RVT_1 PF00078.27 KIY48914.1 - 3.2e-07 30.1 0.0 3.6e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EMP24_GP25L PF01105.24 KIY48916.1 - 0.065 13.2 0.0 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Phage_integrase PF00589.22 KIY48920.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family OmpA_like PF16961.5 KIY48922.1 - 0.067 12.9 0.1 0.097 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family DUF2244 PF10003.9 KIY48922.1 - 3.3 7.4 8.4 2.2 8.0 2.4 2.4 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) DEAD PF00270.29 KIY48923.1 - 2.5e-08 33.9 0.0 5.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY48923.1 - 1.1e-06 29.0 0.1 7.2e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY48923.1 - 6.9e-05 22.9 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIY48923.1 - 0.0082 16.5 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF397 PF04149.12 KIY48928.1 - 0.0028 17.7 0.0 0.0084 16.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Zn_clus PF00172.18 KIY48928.1 - 3 8.1 5.7 3.4 7.9 0.9 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Retrotran_gag_2 PF14223.6 KIY48929.1 - 0.0073 16.0 0.1 0.009 15.7 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Choline_transpo PF04515.12 KIY48930.1 - 3.3e-06 26.6 0.0 3.9e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter SnoaL_2 PF12680.7 KIY48931.1 - 0.00011 22.8 0.0 0.00014 22.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIY48931.1 - 0.00028 21.2 0.0 0.00035 20.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.20 KIY48931.1 - 0.0063 17.1 0.0 0.0079 16.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL PF07366.12 KIY48931.1 - 0.083 12.7 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KIY48932.1 - 0.00015 22.3 0.0 0.0002 21.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIY48932.1 - 0.00076 19.9 0.0 0.001 19.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.20 KIY48932.1 - 0.0011 19.5 0.0 0.0013 19.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain 2OG-FeII_Oxy_3 PF13640.6 KIY48934.1 - 0.00079 20.3 0.0 0.0022 18.8 0.0 1.7 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_9 PF13527.7 KIY48935.1 - 6.7e-08 32.7 0.0 4.6e-05 23.5 0.0 2.1 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY48935.1 - 2.5e-07 31.0 0.0 0.00034 21.0 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY48935.1 - 3e-07 30.4 0.0 2.5e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY48935.1 - 4.7e-05 23.6 0.0 0.00013 22.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Thaumatin PF00314.17 KIY48936.1 - 5.6e-74 248.4 13.4 6.4e-74 248.2 13.4 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIY48936.1 - 0.0042 16.4 2.4 0.0048 16.2 0.1 2.0 2 1 0 2 2 2 1 Beta-1,3-glucanase PPC PF04151.15 KIY48936.1 - 0.36 12.0 5.7 0.56 11.3 3.6 2.5 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain DnaJ PF00226.31 KIY48937.1 - 1.5e-16 60.2 4.9 2.6e-14 53.1 1.6 3.4 2 1 0 2 2 2 2 DnaJ domain DUF4512 PF14975.6 KIY48937.1 - 2.8 8.8 4.3 85 4.0 3.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) 2OG-FeII_Oxy_3 PF13640.6 KIY48938.1 - 1.7e-10 41.7 0.0 3.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4149 PF13664.6 KIY48939.1 - 3.3e-11 43.4 0.7 7.2e-11 42.3 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) PPTA PF01239.22 KIY48940.1 - 2.8e-43 144.4 14.6 5.6e-11 41.8 0.8 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat LsmAD PF06741.13 KIY48941.1 - 4.1e-27 94.5 0.3 7.7e-27 93.6 0.3 1.5 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 KIY48941.1 - 4.7e-05 23.4 0.0 9.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KIY48941.1 - 0.04 14.0 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain ORC6 PF05460.13 KIY48942.1 - 7.4 5.7 9.2 9.6 5.4 9.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) 2OG-FeII_Oxy_3 PF13640.6 KIY48945.1 - 2.3e-09 38.0 0.0 3.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-CCHH PF10283.9 KIY48947.1 - 0.0041 17.1 3.4 0.0065 16.4 3.4 1.5 1 1 0 1 1 1 1 PBZ domain ICL PF00463.21 KIY48948.1 - 4.4e-35 121.2 0.0 4.8e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Phage_int_SAM_1 PF02899.17 KIY48950.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain MFS_1 PF07690.16 KIY48952.1 - 4e-14 52.3 24.6 1e-10 41.1 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ERCC3_RAD25_C PF16203.5 KIY48954.1 - 9.2e-108 359.1 0.0 1.2e-107 358.8 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C PF00271.31 KIY48954.1 - 6.7e-12 45.7 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain E1_dh PF00676.20 KIY48955.1 - 0.00027 20.0 0.0 0.00033 19.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component SRP_TPR_like PF17004.5 KIY48956.1 - 7e-14 51.9 0.1 1.1e-13 51.2 0.1 1.3 1 1 0 1 1 1 1 Putative TPR-like repeat TPR_19 PF14559.6 KIY48956.1 - 2.5e-08 34.3 0.2 0.0013 19.2 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat SRP72 PF08492.12 KIY48956.1 - 1.4e-06 28.7 0.2 1.4e-06 28.7 0.2 1.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 KIY48956.1 - 7.6e-06 26.1 0.8 0.018 15.3 0.1 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KIY48956.1 - 9.3e-06 25.4 1.4 0.086 13.0 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY48956.1 - 0.00014 22.4 0.0 0.53 11.3 0.0 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY48956.1 - 0.0031 17.3 0.4 2.6 8.0 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY48956.1 - 0.0045 17.5 0.3 9 7.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY48956.1 - 0.017 15.2 0.6 0.33 11.1 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY48956.1 - 0.059 13.4 0.0 7.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KIY48956.1 - 0.091 13.1 2.9 0.56 10.5 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_60s PF00428.19 KIY48958.1 - 6.3e-28 97.2 7.6 7.2e-28 97.0 7.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RibD_C PF01872.17 KIY48958.1 - 0.031 14.1 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain F-box-like PF12937.7 KIY48959.1 - 2.1e-05 24.3 0.0 9.8e-05 22.2 0.0 2.2 2 1 0 2 2 2 1 F-box-like DUF3300 PF11737.8 KIY48962.1 - 0.011 15.4 0.8 0.012 15.2 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) DDE_3 PF13358.6 KIY48962.1 - 0.015 15.1 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease Med26 PF08711.11 KIY48964.1 - 0.00023 21.1 0.5 0.00041 20.3 0.5 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Glyco_hydro_18 PF00704.28 KIY48965.1 - 1.3e-30 107.2 0.0 1.6e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Tannase PF07519.11 KIY48966.1 - 2.3e-139 465.3 4.1 2.7e-139 465.1 4.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase SH3_9 PF14604.6 KIY48967.1 - 1.6e-05 24.7 0.0 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KIY48967.1 - 0.008 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY48967.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 SH3 domain IgaA PF07095.11 KIY48968.1 - 0.087 10.8 0.2 0.12 10.4 0.2 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA FMN_red PF03358.15 KIY48969.1 - 2.9e-09 36.9 0.0 3.8e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIY48969.1 - 1.5e-05 24.8 0.0 2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KIY48969.1 - 0.033 14.4 0.0 0.22 11.7 0.0 2.2 1 1 0 1 1 1 0 Flavodoxin Flavodoxin_5 PF12724.7 KIY48969.1 - 0.049 13.9 0.0 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain Ribosomal_L18A PF01775.17 KIY48970.1 - 4.2e-53 178.6 0.1 5e-53 178.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A YccF PF03733.13 KIY48971.1 - 2.4e-10 40.9 6.0 4.9e-10 40.0 6.0 1.5 1 0 0 1 1 1 1 Inner membrane component domain Csm1_N PF18504.1 KIY48971.1 - 0.45 10.9 2.2 1.3 9.4 2.2 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain Cauli_VI PF01693.16 KIY48973.1 - 1.9e-05 24.9 0.1 5.6e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 Caulimovirus viroplasmin Ribosomal_S13 PF00416.22 KIY48974.1 - 5.6e-55 185.2 3.2 6.7e-55 184.9 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KIY48974.1 - 0.005 15.7 0.0 0.016 14.0 0.0 1.6 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KIY48974.1 - 0.065 13.5 0.1 0.19 12.0 0.1 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif Period_C PF12114.8 KIY48974.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF1043 PF06295.12 KIY48976.1 - 0.55 10.2 4.2 0.17 11.9 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) CdvA PF18822.1 KIY48976.1 - 6.5 6.6 9.8 2.1 8.2 1.0 2.7 3 0 0 3 3 3 0 CdvA-like coiled-coil domain T_cell_tran_alt PF15128.6 KIY48977.1 - 0.015 15.0 0.1 3.2 7.6 0.0 2.3 1 1 1 2 2 2 0 T-cell leukemia translocation-altered Bac_rhamnosid6H PF17389.2 KIY48978.1 - 3e-15 56.3 0.1 4.6e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KIY48978.1 - 3.3e-06 26.8 0.0 8.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 KIY48978.1 - 5.3e-05 22.5 1.5 8.3e-05 21.9 1.5 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Trehalase PF01204.18 KIY48978.1 - 0.0016 17.4 0.4 0.0023 16.8 0.4 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 KIY48978.1 - 0.013 14.4 0.5 0.033 13.1 0.6 1.6 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase HycA_repressor PF11046.8 KIY48982.1 - 5.5e-08 33.1 3.3 4.6 7.4 0.0 5.8 1 1 5 6 6 6 5 Transcriptional repressor of hyc and hyp operons DUF3322 PF11795.8 KIY48982.1 - 0.00075 19.6 8.0 26 4.8 0.1 5.4 1 1 5 6 6 6 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF5342 PF17277.2 KIY48982.1 - 0.0012 19.1 2.6 52 4.3 0.0 5.3 1 1 5 6 6 6 0 Family of unknown function (DUF5342) LppX_LprAFG PF07161.13 KIY48982.1 - 0.063 13.1 12.6 41 4.0 0.0 5.7 6 0 0 6 6 6 0 LppX_LprAFG lipoprotein DUF4291 PF14124.6 KIY48982.1 - 2.2 8.1 10.1 17 5.2 0.6 4.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4291) Cementoin PF10511.9 KIY48982.1 - 4.9 7.6 23.5 1.3e+02 3.1 0.2 7.2 7 0 0 7 7 7 0 Trappin protein transglutaminase binding domain DUF3435 PF11917.8 KIY48983.1 - 0.01 14.8 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Phage_integrase PF00589.22 KIY48983.1 - 0.019 14.8 0.0 0.023 14.5 0.0 1.3 1 1 0 1 1 1 0 Phage integrase family FMN_bind PF04205.14 KIY48984.1 - 0.026 15.1 0.2 3.2 8.4 0.1 2.3 2 0 0 2 2 2 0 FMN-binding domain zf-CCHC_4 PF14392.6 KIY48987.1 - 0.0011 18.6 0.5 0.0019 17.9 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY48987.1 - 0.065 13.3 3.7 0.12 12.5 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 KIY48987.1 - 0.21 11.5 4.2 0.43 10.5 4.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 KIY48989.1 - 2.1e-05 24.7 1.4 2.5e-05 24.5 0.5 1.6 2 1 0 2 2 2 1 Retrotransposon gag protein PIF1 PF05970.14 KIY48992.1 - 0.00042 19.6 0.8 0.001 18.3 0.8 1.7 1 1 0 1 1 1 1 PIF1-like helicase PhnA PF03831.14 KIY48992.1 - 0.051 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 PhnA domain KDZ PF18758.1 KIY48995.1 - 1.7e-37 129.2 0.7 5.6e-28 98.1 0.4 2.5 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase Casc1_N PF15927.5 KIY48995.1 - 0.43 10.2 7.6 0.027 14.2 1.2 2.3 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Pkinase PF00069.25 KIY49000.1 - 0.028 13.8 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Fic PF02661.18 KIY49001.1 - 5.1e-11 43.3 0.1 7.4e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Fic/DOC family DUF4381 PF14316.6 KIY49002.1 - 0.15 12.3 0.1 0.42 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) GPP34 PF05719.11 KIY49004.1 - 0.39 10.7 4.8 1 9.4 4.8 2.0 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Cyclin PF08613.11 KIY49005.1 - 0.0027 18.1 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin Transposase_21 PF02992.14 KIY49006.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 Transposase_21 PF02992.14 KIY49007.1 - 0.0072 15.6 0.1 0.04 13.2 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 DUF1804 PF08822.11 KIY49010.1 - 0.078 13.0 0.6 0.11 12.5 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1804) Fic PF02661.18 KIY49011.1 - 0.035 15.0 0.1 0.052 14.5 0.1 1.3 1 0 0 1 1 1 0 Fic/DOC family Retrotran_gag_2 PF14223.6 KIY49012.1 - 5.2e-13 48.8 0.4 1e-08 34.9 0.1 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIY49012.1 - 0.008 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KIY49012.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TFIIF_alpha PF05793.12 KIY49013.1 - 0.004 15.8 4.2 0.0088 14.7 4.2 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Phage_tail_APC PF16778.5 KIY49013.1 - 0.027 14.3 0.1 0.067 13.1 0.1 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone protein zf-CCHC PF00098.23 KIY49013.1 - 0.057 13.5 2.9 0.12 12.5 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle F-box-like PF12937.7 KIY49016.1 - 0.00023 21.0 0.1 0.0006 19.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY49016.1 - 0.019 14.9 2.2 0.19 11.6 2.2 2.7 1 1 0 1 1 1 0 F-box domain Melittin PF01372.17 KIY49016.1 - 0.16 12.0 0.3 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Melittin BNR_4 PF15892.5 KIY49017.1 - 1.2e-15 57.6 0.0 2.5e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-containing family member Fe-S_biosyn PF01521.20 KIY49019.1 - 9.6e-17 61.2 0.0 1.1e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Glyco_hydro_31 PF01055.26 KIY49020.1 - 0.062 12.5 0.0 0.069 12.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 ACPS PF01648.20 KIY49025.1 - 1.1e-12 48.0 0.0 1.2e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Oxidored_FMN PF00724.20 KIY49027.1 - 1.7e-68 231.4 0.0 2.2e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ACPS PF01648.20 KIY49028.1 - 1.9e-15 57.0 0.0 2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Cyclin_N PF00134.23 KIY49029.1 - 1e-09 38.2 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY49029.1 - 1.2e-06 29.0 0.1 1.8e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin SelP_N PF04592.14 KIY49029.1 - 1.4 8.2 9.1 2.1 7.7 9.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2855 PF11017.8 KIY49030.1 - 4.7e-35 121.9 0.5 4.3e-34 118.8 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2855) DUF2855 PF11017.8 KIY49031.1 - 4.7e-50 171.2 0.0 5.4e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) PEX-2N PF09263.10 KIY49031.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal Rhomboid_SP PF12595.8 KIY49032.1 - 0.049 13.0 1.3 0.12 11.8 1.3 1.6 1 0 0 1 1 1 0 Rhomboid serine protease DUF5500 PF17604.2 KIY49032.1 - 0.34 11.0 1.4 46 4.2 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5500) Phage_integrase PF00589.22 KIY49033.1 - 0.0032 17.3 0.1 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 Phage integrase family DUF3435 PF11917.8 KIY49033.1 - 0.019 13.9 0.1 0.058 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) Retrotrans_gag PF03732.17 KIY49034.1 - 0.00028 21.1 0.1 0.00039 20.6 0.1 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein NLBH PF05211.12 KIY49036.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) DLH PF01738.18 KIY49037.1 - 0.00037 20.1 0.0 0.00046 19.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Aminopep PF10023.9 KIY49037.1 - 0.015 14.6 0.1 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative aminopeptidase Aldo_ket_red PF00248.21 KIY49038.1 - 1.2e-24 87.1 0.0 4.6e-24 85.1 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Pyr_redox_2 PF07992.14 KIY49041.1 - 6.3e-40 137.2 0.2 7.9e-40 136.9 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY49041.1 - 1.4e-12 47.9 0.0 1.7e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY49041.1 - 1.9e-05 24.7 0.0 0.026 14.5 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KIY49041.1 - 0.014 14.5 0.1 8.5 5.4 0.0 3.1 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KIY49041.1 - 0.035 13.2 0.0 1.5 7.8 0.0 2.8 1 1 1 3 3 3 0 Glucose inhibited division protein A SH3_5 PF08460.10 KIY49041.1 - 0.075 13.1 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain Eno-Rase_NADH_b PF12242.8 KIY49041.1 - 0.099 12.4 0.4 6.2 6.7 0.0 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Trp_halogenase PF04820.14 KIY49041.1 - 0.11 11.3 0.2 2.3 7.0 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KIY49046.1 - 0.0089 15.3 0.0 0.063 12.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY49046.1 - 0.12 11.7 0.0 14 4.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Peptidase_M16 PF00675.20 KIY49048.1 - 3.2e-36 124.5 0.1 8.9e-36 123.1 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIY49048.1 - 1.2e-32 113.4 0.0 1.8e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain PepSY_TM PF03929.16 KIY49049.1 - 0.0052 16.5 0.2 0.01 15.5 0.2 1.5 1 0 0 1 1 1 1 PepSY-associated TM region SKG6 PF08693.10 KIY49049.1 - 6.5 6.3 9.5 0.11 11.9 1.2 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ANAPC4 PF12896.7 KIY49050.1 - 2 7.8 5.0 3.8 6.9 0.0 3.7 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 4 GIDA_assoc PF13932.6 KIY49051.1 - 0.096 12.9 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 GidA associated domain NPP PF08384.10 KIY49051.1 - 0.13 12.3 1.0 0.67 10.1 0.1 2.1 2 0 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region zf-MYND PF01753.18 KIY49052.1 - 1.3e-08 34.8 6.8 2.2e-08 34.1 6.8 1.3 1 0 0 1 1 1 1 MYND finger NAD_binding_10 PF13460.6 KIY49053.1 - 5.8e-11 42.6 0.0 3.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 KIY49053.1 - 0.00027 20.4 0.1 0.0005 19.6 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY49053.1 - 0.00061 19.4 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ApbA PF02558.16 KIY49053.1 - 0.03 13.9 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DSPc PF00782.20 KIY49054.1 - 1.2e-21 76.9 0.0 1.9e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIY49054.1 - 0.0024 18.2 0.0 0.012 15.9 0.0 2.1 1 1 0 1 1 1 1 Rit1 DUSP-like domain Thaumatin PF00314.17 KIY49056.1 - 4.6e-07 29.7 5.1 4.1e-05 23.3 5.1 2.2 1 1 0 1 1 1 1 Thaumatin family MFS_1 PF07690.16 KIY49057.1 - 2.8e-23 82.4 68.5 5.8e-18 64.9 37.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM43 PF07787.12 KIY49057.1 - 1.1 8.6 5.8 3.3 7.0 5.8 1.9 1 1 0 1 1 1 0 Transmembrane protein 43 DUF2070 PF09843.9 KIY49057.1 - 8.2 4.6 16.1 2.3 6.4 8.4 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) PMT PF02366.18 KIY49058.1 - 1.4e-82 276.9 19.0 1.4e-82 276.9 19.0 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIY49058.1 - 9.3e-56 188.6 12.6 9.3e-56 188.6 12.6 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIY49058.1 - 3.4e-27 95.5 0.1 5.5e-27 94.8 0.1 1.2 1 0 0 1 1 1 1 MIR domain DUF4969 PF16339.5 KIY49058.1 - 0.079 13.3 0.2 0.41 11.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) RTC PF01137.21 KIY49059.1 - 2.4e-79 265.7 0.0 2.7e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KIY49059.1 - 5.7e-22 78.2 0.1 9.3e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CEP76-C2 PF15627.6 KIY49059.1 - 0.1 12.1 0.0 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain Arylsulfotran_2 PF14269.6 KIY49060.1 - 1.4e-34 119.9 0.1 1.7e-34 119.6 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY49060.1 - 3.5e-13 49.2 0.1 3.9e-11 42.5 0.1 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DIOX_N PF14226.6 KIY49061.1 - 8.1e-14 52.4 0.0 1.7e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY49061.1 - 2.8e-10 40.6 0.0 5.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fibrillarin PF01269.17 KIY49062.1 - 2.5e-103 344.1 0.0 3e-103 343.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KIY49062.1 - 9.3e-05 22.2 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KIY49062.1 - 0.00023 21.0 0.1 0.00035 20.4 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KIY49062.1 - 0.023 14.4 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DREV PF05219.12 KIY49062.1 - 0.029 13.5 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.19 KIY49062.1 - 0.035 14.2 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.14 KIY49062.1 - 0.22 10.9 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DEAD PF00270.29 KIY49064.1 - 2.7e-45 154.3 1.0 2.7e-45 154.3 1.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY49064.1 - 4.6e-32 110.7 0.6 2.3e-30 105.2 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY49064.1 - 5e-07 29.9 0.0 8.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIY49064.1 - 2.5e-05 24.6 2.7 0.00025 21.4 0.1 2.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIY49064.1 - 0.0024 17.6 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 KIY49064.1 - 0.015 14.6 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 KIY49064.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.21 KIY49064.1 - 0.075 12.5 0.2 0.096 12.2 0.2 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KIY49064.1 - 0.085 13.1 0.7 0.64 10.3 0.4 2.6 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 KIY49064.1 - 0.088 12.8 0.1 0.4 10.7 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Ras PF00071.22 KIY49065.1 - 1.5e-51 174.2 0.0 1.7e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY49065.1 - 5.5e-30 104.1 0.0 8.3e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY49065.1 - 1.1e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY49065.1 - 6.1e-05 22.6 0.0 0.00075 19.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY49065.1 - 7.8e-05 22.7 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase UreE_N PF02814.15 KIY49065.1 - 0.091 12.4 0.4 1.4 8.6 0.3 2.3 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain DSPc PF00782.20 KIY49067.1 - 5.7e-26 90.9 0.0 7.4e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY49067.1 - 0.00087 18.9 0.0 0.001 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIY49067.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Arginase PF00491.21 KIY49068.1 - 1.1e-81 274.4 0.2 1.4e-81 274.1 0.2 1.1 1 0 0 1 1 1 1 Arginase family UCH PF00443.29 KIY49069.1 - 2.4e-38 132.1 0.0 3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EF_TS PF00889.19 KIY49070.1 - 2.3e-15 56.8 0.0 4.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor TS Ceramidase PF05875.12 KIY49071.1 - 2.7e-76 256.5 1.9 3.3e-76 256.2 1.9 1.0 1 0 0 1 1 1 1 Ceramidase HlyIII PF03006.20 KIY49071.1 - 0.14 11.8 5.8 0.26 11.0 5.5 1.5 1 1 0 1 1 1 0 Haemolysin-III related Ribosomal_S8e PF01201.22 KIY49072.1 - 1.3e-55 187.4 0.7 1.8e-55 186.9 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e UDPGP PF01704.18 KIY49073.1 - 1e-195 650.2 1.0 1.2e-195 650.0 1.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NADH_B2 PF14813.6 KIY49075.1 - 4e-05 23.3 0.0 4.4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 F-box-like PF12937.7 KIY49077.1 - 0.00037 20.3 2.6 0.00098 19.0 1.7 2.3 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY49077.1 - 0.014 15.8 3.4 41 4.8 0.0 5.3 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY49077.1 - 0.036 14.0 0.3 12 5.9 0.1 3.1 2 0 0 2 2 2 0 F-box domain Metallophos PF00149.28 KIY49078.1 - 3.6e-13 50.5 0.1 5.9e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY49078.1 - 0.0015 18.8 0.0 0.0025 18.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CPSase_sm_chain PF00988.22 KIY49079.1 - 4.8e-46 155.8 0.0 7.7e-46 155.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KIY49079.1 - 2.1e-37 128.8 0.0 3e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIY49079.1 - 8.3e-08 32.2 0.1 2.2e-06 27.6 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KIY49079.1 - 0.033 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family BSD PF03909.17 KIY49080.1 - 1.7e-10 40.8 0.1 4.4e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 BSD domain KfrA_N PF11740.8 KIY49080.1 - 0.021 15.5 0.1 0.33 11.7 0.0 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term EF-G-binding_N PF07299.11 KIY49080.1 - 0.026 15.0 0.0 0.072 13.6 0.0 1.7 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal PTRF_SDPR PF15237.6 KIY49080.1 - 0.096 12.3 0.1 0.096 12.3 0.1 2.3 2 0 0 2 2 2 0 PTRF/SDPR family DUF4852 PF16144.5 KIY49080.1 - 0.12 12.5 0.1 0.63 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) TACC_C PF05010.14 KIY49080.1 - 0.25 11.1 2.0 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Pkinase PF00069.25 KIY49081.1 - 2.9e-72 243.2 0.0 3.5e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49081.1 - 1.9e-31 109.3 0.0 2.4e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY49081.1 - 2.6e-07 29.8 0.0 5.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY49081.1 - 2.3e-05 23.8 0.0 4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY49081.1 - 0.02 14.3 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIY49082.1 - 2.5e-41 141.8 0.0 3.7e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49082.1 - 3.5e-26 92.0 0.0 5.4e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY49082.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KIY49082.1 - 0.034 14.1 0.3 0.066 13.1 0.3 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Homeodomain PF00046.29 KIY49083.1 - 1.3e-15 57.0 0.1 1.4e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Homeodomain Metallophos PF00149.28 KIY49084.1 - 2.7e-06 28.0 0.0 4.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase_fungal PF17667.1 KIY49085.1 - 4.6e-22 78.4 0.0 1.6e-16 60.1 0.0 2.4 2 1 0 2 2 2 2 Fungal protein kinase Scs3p PF10261.9 KIY49086.1 - 5.2e-42 144.1 6.0 4.2e-35 121.4 0.5 2.2 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM 2-Hacid_dh_C PF02826.19 KIY49087.1 - 6.6e-47 159.2 0.0 9.3e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY49087.1 - 3.8e-17 62.2 0.0 5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY49087.1 - 7.2e-05 23.0 0.0 0.0002 21.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KIY49087.1 - 0.036 14.5 0.4 11 6.5 0.0 3.0 4 0 0 4 4 4 0 Putative NAD(P)-binding DUF3884 PF13024.6 KIY49087.1 - 0.042 13.4 0.0 8.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) Shikimate_DH PF01488.20 KIY49087.1 - 0.1 12.6 0.0 0.42 10.7 0.0 1.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase EXS PF03124.14 KIY49088.1 - 2.6e-100 336.0 11.5 2.9e-100 335.8 11.5 1.0 1 0 0 1 1 1 1 EXS family Anticodon_1 PF08264.13 KIY49088.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA zf-C2H2_jaz PF12171.8 KIY49089.1 - 8.8e-08 32.2 0.1 1.7e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY49089.1 - 5.3e-06 26.6 0.4 9.3e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KIY49089.1 - 0.00011 22.3 1.0 0.00017 21.6 0.1 1.8 2 0 0 2 2 2 1 DBF zinc finger SNRNP27 PF08648.12 KIY49089.1 - 0.00022 21.2 1.2 0.00022 21.2 1.2 2.0 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins UNC-79 PF14776.6 KIY49089.1 - 0.012 14.4 0.4 0.017 13.9 0.4 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 zf-C2H2 PF00096.26 KIY49089.1 - 0.015 15.7 0.8 0.025 15.0 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY49089.1 - 0.039 14.8 0.1 0.077 13.9 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KIY49089.1 - 0.089 12.4 0.0 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain B12D PF06522.11 KIY49089.1 - 9.7 6.1 7.3 2.1 8.2 3.7 1.8 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit tRNA-synt_1 PF00133.22 KIY49090.1 - 1.4e-222 740.3 0.0 2.1e-222 739.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIY49090.1 - 4.8e-26 91.6 0.3 9.4e-26 90.6 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIY49090.1 - 9.1e-14 51.0 0.6 4.1e-05 22.5 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Fungal_trans PF04082.18 KIY49091.1 - 1.8e-14 53.4 0.3 3.9e-14 52.3 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY49091.1 - 8.5e-05 22.6 15.0 0.00017 21.7 15.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 KIY49091.1 - 0.19 11.6 0.1 0.41 10.6 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DIOX_N PF14226.6 KIY49092.1 - 1e-26 94.0 0.0 1.4e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY49092.1 - 3.9e-20 72.2 0.0 7.5e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PQQ PF01011.21 KIY49094.1 - 0.0018 18.1 0.9 0.086 12.8 0.1 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 KIY49094.1 - 0.081 13.4 3.5 0.88 10.1 2.3 3.1 2 1 1 3 3 3 0 PQQ-like domain Nup160 PF11715.8 KIY49094.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIY49094.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain BAG PF02179.16 KIY49095.1 - 3.3e-19 69.1 0.2 4.6e-19 68.6 0.2 1.2 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KIY49095.1 - 4.9e-06 26.2 0.0 1.1e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Pkinase PF00069.25 KIY49096.1 - 9.5e-56 189.1 0.0 1.1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49096.1 - 1.2e-36 126.3 0.0 1.6e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY49096.1 - 1.5e-06 27.7 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY49096.1 - 0.0085 16.0 0.9 0.31 10.9 0.0 2.9 2 2 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY49096.1 - 0.05 12.5 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIY49096.1 - 0.057 12.2 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase zf-C3HC4_2 PF13923.6 KIY49097.1 - 3.9e-08 33.0 3.5 3.9e-08 33.0 3.5 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 KIY49097.1 - 1.2e-05 25.4 0.4 0.046 13.7 0.1 2.3 2 0 0 2 2 2 2 Seven in absentia protein family zf-C3HC4 PF00097.25 KIY49097.1 - 1.9e-05 24.4 2.8 5.4e-05 23.0 2.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY49097.1 - 3.1e-05 24.2 3.3 3.1e-05 24.2 3.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY49097.1 - 3.4e-05 23.8 3.9 0.00011 22.2 3.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 KIY49097.1 - 6.8e-05 23.2 10.0 0.22 12.0 0.0 2.8 2 1 0 2 2 2 2 TRAF-like zinc-finger zf-RING_5 PF14634.6 KIY49097.1 - 0.00012 22.0 2.4 0.00012 22.0 2.4 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KIY49097.1 - 0.00014 22.0 1.3 0.00014 22.0 1.3 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KIY49097.1 - 0.00014 21.6 1.7 0.00014 21.6 1.7 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 KIY49097.1 - 0.00078 19.3 1.3 0.00078 19.3 1.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ZapB PF06005.12 KIY49097.1 - 0.0013 19.1 0.4 0.19 12.2 0.0 2.4 2 0 0 2 2 2 1 Cell division protein ZapB zf-RING_6 PF14835.6 KIY49097.1 - 0.0087 15.9 0.2 0.019 14.8 0.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein BDV_P24 PF06595.11 KIY49097.1 - 0.011 15.6 0.2 0.052 13.4 0.2 2.0 2 1 0 2 2 2 0 Borna disease virus P24 protein Prok-RING_4 PF14447.6 KIY49097.1 - 0.013 15.3 2.0 0.013 15.3 2.0 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 KIY49097.1 - 0.02 14.8 1.0 0.055 13.4 1.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY49097.1 - 0.022 14.9 1.6 0.062 13.5 1.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Csm1_N PF18504.1 KIY49097.1 - 0.034 14.5 0.7 0.47 10.8 0.1 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain zf-P11 PF03854.14 KIY49097.1 - 0.069 12.8 0.5 0.15 11.7 0.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger Rootletin PF15035.6 KIY49097.1 - 0.095 12.7 0.2 40 4.1 0.0 2.9 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.21 KIY49097.1 - 0.12 12.5 1.0 15 5.8 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor zf-TRAF PF02176.18 KIY49097.1 - 0.12 13.1 7.6 1.3 9.8 1.0 3.2 3 0 0 3 3 3 0 TRAF-type zinc finger HAP1_N PF04849.13 KIY49097.1 - 0.17 11.1 3.5 1.2 8.3 0.4 2.1 2 0 0 2 2 2 0 HAP1 N-terminal conserved region GIT_CC PF16559.5 KIY49097.1 - 0.19 11.6 0.2 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor JIP_LZII PF16471.5 KIY49097.1 - 0.42 10.8 2.7 13 6.0 0.2 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II zf-U11-48K PF05253.12 KIY49097.1 - 8.2 6.5 11.7 1.7 8.6 2.0 3.2 4 0 0 4 4 3 0 U11-48K-like CHHC zinc finger rhaM PF05336.13 KIY49098.1 - 8e-35 119.2 0.1 9e-35 119.0 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase ALAD PF00490.21 KIY49099.1 - 8.1e-122 406.3 0.0 1e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DSS1_SEM1 PF05160.13 KIY49100.1 - 2.1e-22 78.9 8.1 2.1e-22 78.9 8.1 1.4 1 1 0 1 1 1 1 DSS1/SEM1 family Aldo_ket_red PF00248.21 KIY49102.1 - 4e-45 154.3 0.0 4.5e-36 124.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DPBB_1 PF03330.18 KIY49104.1 - 1.2e-05 25.5 0.0 2.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase Bromodomain PF00439.25 KIY49106.1 - 1.6e-23 82.5 0.3 2.8e-23 81.8 0.3 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KIY49106.1 - 3.1e-07 30.6 0.0 5.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY49106.1 - 1.4e-06 28.2 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY49106.1 - 0.00059 20.2 0.1 0.0011 19.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EnY2 PF10163.9 KIY49106.1 - 0.033 14.6 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Transcription factor e(y)2 BSD PF03909.17 KIY49107.1 - 1.3e-20 73.1 0.1 5.2e-14 52.0 0.0 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KIY49107.1 - 5.1e-16 58.8 0.1 5e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Type_III_YscX PF09474.10 KIY49107.1 - 0.0061 16.9 1.6 0.017 15.4 1.6 1.7 1 0 0 1 1 1 1 Type III secretion system YscX (type_III_YscX) ImpA_N PF06812.12 KIY49107.1 - 0.037 14.2 0.4 0.14 12.2 0.4 2.0 1 1 0 1 1 1 0 ImpA, N-terminal, type VI secretion system GvpG PF05120.12 KIY49107.1 - 0.04 13.9 0.3 0.13 12.3 0.3 1.8 1 0 0 1 1 1 0 Gas vesicle protein G DUF4460 PF14687.6 KIY49107.1 - 0.11 12.5 0.5 0.53 10.4 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) LAG1-DNAbind PF09271.11 KIY49108.1 - 4.5e-44 150.7 0.0 6.8e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KIY49108.1 - 5.6e-18 65.6 0.0 6.9e-17 62.1 0.0 2.5 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain TIG PF01833.24 KIY49108.1 - 0.00046 20.2 0.0 0.0015 18.5 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain Phage_integrase PF00589.22 KIY49109.1 - 0.0049 16.7 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family DEAD PF00270.29 KIY49111.1 - 2.5e-38 131.6 0.0 3.9e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KIY49111.1 - 2.8e-19 69.1 0.6 5.9e-19 68.1 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KIY49111.1 - 3e-17 63.0 0.0 1.7e-16 60.5 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY49111.1 - 0.0071 16.4 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pro_isomerase PF00160.21 KIY49112.1 - 2.7e-43 148.0 0.2 3.4e-43 147.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CASP_C PF08172.12 KIY49113.1 - 2.6e-74 249.8 0.2 2.6e-74 249.8 0.2 3.9 2 1 1 4 4 4 1 CASP C terminal ADIP PF11559.8 KIY49113.1 - 0.013 15.6 12.0 0.013 15.6 12.0 5.2 4 1 0 5 5 5 0 Afadin- and alpha -actinin-Binding CtIP_N PF10482.9 KIY49113.1 - 0.024 14.7 2.1 0.024 14.7 2.1 6.0 4 2 2 6 6 6 0 Tumour-suppressor protein CtIP N-terminal domain DUF2935 PF11155.8 KIY49113.1 - 0.027 14.8 7.3 1.4 9.3 0.0 3.9 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DUF3138 PF11336.8 KIY49113.1 - 3.4 6.2 4.1 1.1 7.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) V-SNARE PF05008.15 KIY49114.1 - 6.7e-15 55.2 1.3 1.6e-14 54.0 0.2 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KIY49114.1 - 2.1e-13 50.3 3.0 2.1e-13 50.3 3.0 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus RIFIN PF02009.16 KIY49114.1 - 0.22 11.4 1.9 0.3 10.9 1.1 1.5 1 1 0 1 1 1 0 Rifin ZapB PF06005.12 KIY49116.1 - 0.0055 17.1 1.2 0.0055 17.1 1.2 2.0 2 0 0 2 2 2 1 Cell division protein ZapB HMMR_C PF15908.5 KIY49116.1 - 0.0056 17.0 2.9 0.0094 16.2 2.9 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal HALZ PF02183.18 KIY49116.1 - 0.012 15.8 1.2 0.026 14.7 1.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 KIY49116.1 - 0.03 14.1 2.0 0.083 12.7 1.8 1.8 1 1 0 1 1 1 0 Septum formation initiator FAM104 PF15434.6 KIY49116.1 - 0.031 14.8 3.6 0.031 14.8 3.6 1.7 2 0 0 2 2 2 0 Family 104 DUF4097 PF13349.6 KIY49116.1 - 0.038 13.3 0.2 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative adhesin APG6_N PF17675.1 KIY49116.1 - 0.066 13.7 3.1 0.11 13.0 3.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KIY49116.1 - 0.36 11.7 6.6 1 10.3 6.6 1.8 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Cnn_1N PF07989.11 KIY49116.1 - 0.88 9.8 5.6 3.6 7.8 1.0 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Plavaka PF18759.1 KIY49117.1 - 8.3e-110 367.0 0.0 1.1e-109 366.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase baeRF_family6 PF18848.1 KIY49117.1 - 0.13 12.7 0.1 1.1 9.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 6 PT PF04886.12 KIY49118.1 - 5.7e-09 35.4 19.6 1.3e-05 24.6 2.2 4.0 2 1 1 3 3 3 3 PT repeat NQR2_RnfD_RnfE PF03116.15 KIY49119.1 - 0.00042 19.8 0.3 0.00065 19.2 0.3 1.2 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family fn3_2 PF16893.5 KIY49122.1 - 3.4e-38 129.7 0.2 3.4e-38 129.7 0.2 1.8 3 0 0 3 3 3 1 Fibronectin type III domain CHS5_N PF16892.5 KIY49122.1 - 1.1e-26 92.5 0.1 1.9e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KIY49122.1 - 1.6e-09 38.0 0.0 2.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIY49122.1 - 1.2e-08 34.7 0.0 9.5e-08 31.9 0.0 2.2 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.21 KIY49122.1 - 5.4e-06 26.7 0.2 1.4e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 KIY49122.1 - 0.00032 20.9 0.0 0.00052 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 KIY49122.1 - 0.0046 17.3 0.0 0.008 16.6 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain E1_dh PF00676.20 KIY49124.1 - 3.2e-27 95.2 0.6 9.1e-27 93.8 0.6 1.6 1 1 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_72 PF03198.14 KIY49125.1 - 9.7e-91 304.3 1.2 1.6e-90 303.6 1.2 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KIY49125.1 - 5.7e-16 59.0 1.9 5.7e-16 59.0 1.9 2.1 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.18 KIY49125.1 - 0.0032 17.0 0.0 0.01 15.3 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Catalase PF00199.19 KIY49126.1 - 3.8e-150 500.3 0.1 4.9e-150 499.9 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIY49126.1 - 2.5e-12 46.8 0.0 8.6e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Methyltransf_2 PF00891.18 KIY49128.1 - 2.2e-21 76.1 0.0 5.3e-18 65.1 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_23 PF13489.6 KIY49128.1 - 0.00034 20.5 0.0 0.00067 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY49128.1 - 0.001 19.7 0.0 0.0037 17.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY49128.1 - 0.084 13.6 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain P19Arf_N PF07392.12 KIY49128.1 - 0.15 12.5 0.5 0.38 11.3 0.0 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Methyltransf_4 PF02390.17 KIY49128.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Abhydrolase_3 PF07859.13 KIY49133.1 - 1.7e-23 83.6 0.0 2.1e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY49133.1 - 4.7e-12 45.5 0.0 7.3e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KIY49133.1 - 0.0042 17.7 0.2 0.0052 17.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KIY49133.1 - 0.0063 16.3 0.1 0.056 13.2 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Clathrin PF00637.20 KIY49134.1 - 8.1e-23 80.9 0.5 2.3e-22 79.4 0.2 2.0 3 0 0 3 3 3 1 Region in Clathrin and VPS DUF688 PF05097.12 KIY49134.1 - 0.026 13.7 0.7 0.039 13.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) CENP-B_dimeris PF09026.10 KIY49134.1 - 0.029 14.8 2.6 0.081 13.3 2.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Vps39_2 PF10367.9 KIY49134.1 - 0.038 14.4 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KIY49134.1 - 0.15 12.3 1.8 0.99 9.7 0.1 3.0 3 1 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 zf-RING_UBOX PF13445.6 KIY49134.1 - 0.24 11.5 1.2 0.6 10.2 1.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KIY49134.1 - 1.6 9.1 4.6 0.33 11.3 0.3 2.0 2 0 0 2 2 2 0 Ring finger domain MRI PF15325.6 KIY49134.1 - 2.3 9.3 6.0 6 8.0 6.0 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection TMEM135_C_rich PF15982.5 KIY49135.1 - 2e-06 28.4 1.4 0.017 15.7 0.1 3.3 2 1 1 3 3 3 2 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 KIY49135.1 - 0.21 11.9 3.5 1.5 9.2 0.1 2.9 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family HemY_N PF07219.13 KIY49136.1 - 0.016 15.4 2.0 0.07 13.3 2.0 2.0 1 1 0 1 1 1 0 HemY protein N-terminus Trp_oprn_chp PF09534.10 KIY49136.1 - 0.1 12.4 0.4 4.3 7.1 0.0 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) His_Phos_2 PF00328.22 KIY49137.1 - 0.00015 21.3 3.0 0.34 10.2 0.3 3.7 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Minor_capsid_3 PF12691.7 KIY49137.1 - 0.11 12.8 0.1 3.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Minor capsid protein from bacteriophage Peptidase_M24 PF00557.24 KIY49138.1 - 3e-47 161.0 0.0 3.8e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4949 PF16307.5 KIY49138.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) F-box PF00646.33 KIY49140.1 - 0.00012 21.9 0.3 0.00012 21.9 0.3 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY49140.1 - 0.0006 19.6 3.0 0.0093 15.8 0.2 2.8 2 0 0 2 2 2 1 F-box-like HOASN PF14515.6 KIY49140.1 - 0.022 15.1 0.2 0.069 13.5 0.2 1.8 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices hnRNP_Q_AcD PF18360.1 KIY49140.1 - 0.064 13.2 0.1 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Spc7 PF08317.11 KIY49140.1 - 0.46 9.3 1.6 0.71 8.7 1.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2828 PF11443.8 KIY49141.1 - 6.6e-188 625.7 0.0 4.9e-186 619.6 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) FtsJ PF01728.19 KIY49142.1 - 9.6e-10 38.8 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase RGS12_us1 PF16613.5 KIY49143.1 - 0.079 13.3 0.3 0.13 12.5 0.3 1.4 1 0 0 1 1 1 0 Unstructured region of RGS12 SR-25 PF10500.9 KIY49144.1 - 2.9 7.4 7.4 4.4 6.9 7.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LPG_synthase_TM PF03706.13 KIY49145.1 - 0.78 9.2 8.8 0.82 9.1 8.8 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region MAGI_u1 PF16663.5 KIY49146.1 - 0.17 12.0 0.2 0.17 12.0 0.2 1.9 2 0 0 2 2 2 0 Unstructured region on MAGI Abhydrolase_1 PF00561.20 KIY49147.1 - 4.2e-19 69.2 0.1 9.1e-16 58.3 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY49147.1 - 1e-17 65.5 3.4 1e-17 65.5 3.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY49147.1 - 5.9e-17 61.7 0.7 2.1e-16 59.9 0.7 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KIY49147.1 - 2.5e-05 24.1 0.1 0.21 11.4 0.1 2.9 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KIY49147.1 - 3e-05 24.1 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KIY49147.1 - 3.5e-05 23.4 0.0 0.056 12.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KIY49147.1 - 0.0016 18.1 0.2 0.024 14.2 0.1 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Esterase_phd PF10503.9 KIY49147.1 - 0.0021 17.6 1.7 0.072 12.6 0.7 2.4 1 1 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 KIY49147.1 - 0.0036 17.2 0.2 0.0058 16.5 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KIY49147.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ndr PF03096.14 KIY49147.1 - 0.091 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Esterase PF00756.20 KIY49147.1 - 0.13 11.9 0.6 0.3 10.7 0.6 1.6 1 1 0 1 1 1 0 Putative esterase TAF4 PF05236.14 KIY49148.1 - 1.1e-32 113.9 5.4 1.7e-32 113.3 5.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF3807 PF12720.7 KIY49148.1 - 0.41 10.9 8.3 1.1 9.5 8.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Menin PF05053.13 KIY49148.1 - 1.9 6.8 11.4 2.9 6.2 11.4 1.2 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 KIY49148.1 - 9.7 3.2 12.0 15 2.5 12.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NmrA PF05368.13 KIY49153.1 - 6.5e-16 58.6 0.0 8.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY49153.1 - 2.1e-07 31.0 0.0 3.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY49153.1 - 4.7e-05 23.0 0.0 6.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY49153.1 - 0.061 12.3 0.0 0.076 12.0 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_3 PF00933.21 KIY49155.1 - 2e-21 76.7 0.0 2.7e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain NmrA PF05368.13 KIY49157.1 - 3.4e-27 95.5 0.0 5.4e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY49157.1 - 6.6e-08 32.6 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY49157.1 - 0.0018 17.8 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Tristanin_u2 PF16638.5 KIY49158.1 - 5 8.0 8.8 11 6.8 8.8 1.8 1 1 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers DUF563 PF04577.14 KIY49159.1 - 7.4e-21 75.2 0.3 4.9e-20 72.6 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF563) 7TM_GPCR_Srd PF10317.9 KIY49160.1 - 0.058 12.6 4.6 0.11 11.7 0.0 3.1 3 1 1 4 4 4 0 Serpentine type 7TM GPCR chemoreceptor Srd CNOT11 PF10155.9 KIY49163.1 - 1.7e-16 60.5 0.0 2.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Pkinase_fungal PF17667.1 KIY49164.1 - 0.005 15.7 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase tRNA_m1G_MT PF01746.21 KIY49165.1 - 9e-27 94.0 0.0 1.5e-21 77.0 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Mito_carr PF00153.27 KIY49166.1 - 9.3e-47 156.9 4.0 8.4e-16 57.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KIY49166.1 - 0.044 13.9 0.3 1.1 9.4 0.2 2.4 2 0 0 2 2 2 0 PrcB C-terminal UQ_con PF00179.26 KIY49167.1 - 1.9e-14 53.5 0.0 3.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.21 KIY49167.1 - 1.7e-05 25.0 1.9 3.6e-05 23.9 1.9 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain UBA PF00627.31 KIY49167.1 - 0.0016 18.3 0.3 0.0047 16.8 0.3 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Arb2 PF09757.9 KIY49167.1 - 0.11 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Arb2 domain IL11 PF07400.11 KIY49167.1 - 0.5 10.0 2.5 3.7 7.2 0.0 2.9 2 1 0 2 2 2 0 Interleukin 11 DUF1843 PF08898.10 KIY49167.1 - 3.4 8.2 5.6 2.8 8.5 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) EI24 PF07264.11 KIY49168.1 - 9.1e-10 39.1 3.7 1.7e-09 38.2 3.7 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FF PF01846.19 KIY49169.1 - 9.2e-36 121.8 16.5 2.3e-10 40.5 0.0 6.0 6 0 0 6 6 6 5 FF domain WW PF00397.26 KIY49169.1 - 3.6e-11 43.0 2.0 7.1e-08 32.4 0.1 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KIY49169.1 - 6.2e-06 26.8 9.1 0.054 14.2 0.0 4.9 3 2 2 5 5 5 2 p190-A and -B Rho GAPs FF domain Exonuc_VII_L PF02601.15 KIY49169.1 - 9.3 5.7 22.6 10 5.6 3.4 2.9 2 1 0 2 2 2 0 Exonuclease VII, large subunit RasGAP_C PF03836.15 KIY49170.1 - 1.6e-42 144.9 4.0 1.6e-42 144.9 4.0 2.3 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 KIY49170.1 - 1.4e-37 129.5 0.1 3.1e-37 128.3 0.1 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 KIY49170.1 - 8.2e-18 62.5 48.0 0.004 16.8 2.2 12.2 12 0 0 12 12 12 8 IQ calmodulin-binding motif CH PF00307.31 KIY49170.1 - 5.2e-14 52.4 0.0 1.4e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain Med4 PF10018.9 KIY49170.1 - 3.1 7.4 10.2 4.3 7.0 2.0 3.1 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1664 PF07889.12 KIY49170.1 - 9.8 6.2 7.1 42 4.2 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) His_Phos_2 PF00328.22 KIY49171.1 - 3.2e-81 273.6 0.0 4e-81 273.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KIY49171.1 - 1.4e-36 124.5 0.0 4.1e-36 123.0 0.0 1.9 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KIY49171.1 - 8.6e-07 28.7 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain UQ_con PF00179.26 KIY49172.1 - 1e-15 57.6 0.0 1.4e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 KIY49172.1 - 0.1 11.4 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) PTPA PF03095.15 KIY49173.1 - 1.2e-99 333.6 0.0 1.3e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Pkinase PF00069.25 KIY49174.1 - 1.1e-14 54.5 0.0 2.9e-14 53.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIY49174.1 - 1.7e-08 33.7 0.0 2.2e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KIY49174.1 - 4e-06 26.3 0.0 7.7e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY49174.1 - 0.00085 19.3 0.2 0.0015 18.5 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY49174.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY49174.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ABC_membrane PF00664.23 KIY49175.1 - 1.4e-42 146.3 1.3 2e-42 145.8 1.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIY49175.1 - 1e-32 113.5 0.0 2.7e-32 112.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY49175.1 - 0.00025 20.6 2.0 0.0046 16.4 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 KIY49175.1 - 0.045 13.5 0.0 0.17 11.6 0.0 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 KIY49175.1 - 0.062 12.6 0.1 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 KIY49175.1 - 0.067 13.6 0.2 0.39 11.1 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain MHYT PF03707.16 KIY49175.1 - 0.084 13.0 1.9 0.86 9.8 0.3 2.7 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat VanY PF02557.17 KIY49175.1 - 0.099 12.4 0.2 9.4 6.0 0.0 2.3 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase His_biosynth PF00977.21 KIY49176.1 - 2.1e-33 115.7 0.0 2.8e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KIY49176.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family CNP1 PF08750.11 KIY49176.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 CNP1-like family Ribosomal_L29 PF00831.23 KIY49177.1 - 1.4e-19 69.8 1.8 1.4e-19 69.8 1.8 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein SieB PF14163.6 KIY49177.1 - 0.013 15.0 1.9 0.023 14.2 1.9 1.6 1 1 0 1 1 1 0 Super-infection exclusion protein B Annexin PF00191.20 KIY49177.1 - 0.037 14.1 0.8 0.068 13.2 0.1 1.8 2 0 0 2 2 2 0 Annexin FlgN PF05130.12 KIY49178.1 - 0.27 11.8 0.0 0.27 11.8 0.0 2.9 3 0 0 3 3 3 0 FlgN protein Shugoshin_N PF07558.11 KIY49178.1 - 0.92 9.4 6.6 0.21 11.5 0.8 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF4337 PF14235.6 KIY49178.1 - 8.5 6.5 6.5 19 5.4 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MFS_1 PF07690.16 KIY49179.1 - 6.7e-33 114.1 28.6 6.7e-33 114.1 28.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Caveolin PF01146.17 KIY49179.1 - 0.0096 15.9 1.8 0.025 14.5 0.2 2.4 2 0 0 2 2 2 1 Caveolin HSP90 PF00183.18 KIY49180.1 - 1.6e-125 420.0 0.7 2e-125 419.6 0.7 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 KIY49180.1 - 1.2e-08 34.9 0.0 2.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIY49180.1 - 6.7e-06 26.6 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5347 PF17282.2 KIY49180.1 - 0.023 15.0 0.2 0.063 13.6 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5347) AAA_28 PF13521.6 KIY49180.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4637 PF15470.6 KIY49181.1 - 0.23 11.2 3.7 0.57 9.9 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Kelch_4 PF13418.6 KIY49182.1 - 7.3e-15 54.7 8.6 0.0091 16.0 0.2 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KIY49182.1 - 1.5e-10 40.8 6.7 0.042 13.8 0.0 5.0 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KIY49182.1 - 3e-09 36.8 7.0 0.14 12.5 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KIY49182.1 - 1.1e-06 28.8 27.0 0.00072 19.8 0.1 6.5 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KIY49182.1 - 0.00017 21.1 5.7 3.1 7.5 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KIY49182.1 - 0.0051 16.8 4.7 4.8 7.3 0.0 5.1 5 0 0 5 5 5 1 Kelch motif DUF2434 PF10361.9 KIY49182.1 - 0.0091 15.0 1.4 0.089 11.8 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2434) Phage_Gp23 PF10669.9 KIY49182.1 - 0.23 11.8 0.0 0.6 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Cid2 PF09774.9 KIY49183.1 - 5.1e-26 92.0 7.7 8.6e-26 91.3 7.7 1.3 1 0 0 1 1 1 1 Caffeine-induced death protein 2 GPP34 PF05719.11 KIY49183.1 - 0.063 13.3 0.7 0.11 12.5 0.7 1.5 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) CM_2 PF01817.21 KIY49183.1 - 0.12 12.7 1.8 0.19 12.1 0.1 2.1 2 1 0 2 2 2 0 Chorismate mutase type II GILT PF03227.16 KIY49185.1 - 4e-17 62.4 0.3 6.6e-17 61.7 0.3 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF953 PF06110.11 KIY49185.1 - 0.041 13.5 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) TGBp3 PF02495.17 KIY49185.1 - 0.078 12.7 0.4 0.078 12.7 0.4 1.9 2 0 0 2 2 2 0 Triple gene block 3 Yos1 PF08571.10 KIY49186.1 - 1e-32 112.2 0.1 1.3e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 Yos1-like Ribosomal_L22 PF00237.19 KIY49187.1 - 6.8e-22 77.7 1.0 9.3e-22 77.2 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e SpoU_sub_bind PF08032.12 KIY49187.1 - 0.091 13.0 0.2 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding UCR_14kD PF02271.16 KIY49187.1 - 0.11 12.5 0.9 0.77 9.8 0.1 2.2 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit WD40 PF00400.32 KIY49188.1 - 0.014 16.2 0.3 0.014 16.2 0.3 2.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Ribophorin_I PF04597.14 KIY49189.1 - 3.7e-128 428.5 2.7 4.1e-128 428.3 2.7 1.0 1 0 0 1 1 1 1 Ribophorin I CE2_N PF17996.1 KIY49192.1 - 0.013 15.5 0.0 0.047 13.7 0.0 1.9 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Adeno_E3_CR2 PF02439.15 KIY49192.1 - 0.023 14.4 0.2 0.055 13.2 0.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MGC-24 PF05283.11 KIY49193.1 - 0.016 15.6 1.1 0.016 15.6 1.1 3.1 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gly-zipper_Omp PF13488.6 KIY49193.1 - 0.13 12.3 1.6 0.15 12.1 0.2 1.7 2 0 0 2 2 2 0 Glycine zipper Orf78 PF06024.12 KIY49193.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Abhydrolase_6 PF12697.7 KIY49194.1 - 1.8e-06 28.7 0.2 3.1e-06 28.0 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY49194.1 - 9.8e-05 21.7 0.1 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIY49194.1 - 0.0014 18.8 0.2 0.0051 17.0 0.1 2.0 2 1 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KIY49194.1 - 0.0032 17.2 0.0 0.011 15.5 0.0 1.7 1 1 1 2 2 2 1 PGAP1-like protein DUF900 PF05990.12 KIY49194.1 - 0.011 15.3 0.0 0.079 12.5 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 KIY49194.1 - 0.011 15.2 0.5 0.085 12.4 0.5 2.1 1 1 0 1 1 1 0 Putative serine esterase (DUF676) UPF0227 PF05728.12 KIY49194.1 - 0.013 15.5 0.2 0.029 14.3 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Cob_adeno_trans PF01923.18 KIY49194.1 - 0.022 14.9 0.0 4 7.6 0.0 3.1 3 0 0 3 3 3 0 Cobalamin adenosyltransferase DUF2974 PF11187.8 KIY49194.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FAM199X PF15814.5 KIY49194.1 - 0.073 12.1 2.0 0.18 10.8 1.2 1.8 2 0 0 2 2 2 0 Protein family FAM199X SR-25 PF10500.9 KIY49194.1 - 0.084 12.5 9.0 0.024 14.3 3.2 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3987 PF13148.6 KIY49194.1 - 0.096 11.7 5.4 0.16 10.9 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Abhydrolase_1 PF00561.20 KIY49194.1 - 0.19 11.3 1.0 0.43 10.2 0.3 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold XPA_C PF05181.12 KIY49195.1 - 2.5e-24 85.0 1.2 5.4e-24 83.9 1.2 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KIY49195.1 - 0.023 14.7 5.7 0.023 14.7 5.7 2.4 2 0 0 2 2 2 0 XPA protein N-terminal TniQ PF06527.11 KIY49195.1 - 0.26 12.0 2.7 4.7 7.9 0.4 2.4 2 1 0 2 2 2 0 TniQ PPR_2 PF13041.6 KIY49196.1 - 6.1e-23 80.8 2.5 8.9e-13 48.2 0.0 6.2 7 0 0 7 7 7 3 PPR repeat family PPR PF01535.20 KIY49196.1 - 4.3e-09 36.0 3.4 0.028 14.6 0.1 6.3 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.7 KIY49196.1 - 1.6e-05 24.5 0.0 0.53 10.0 0.2 4.3 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KIY49196.1 - 2.9e-05 24.1 0.0 0.32 11.1 0.0 4.0 5 0 0 5 5 5 2 Pentatricopeptide repeat domain TPR_19 PF14559.6 KIY49196.1 - 0.035 14.6 0.2 6.1 7.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1804 PF08822.11 KIY49196.1 - 0.069 13.1 0.8 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1804) Nnf1 PF03980.14 KIY49196.1 - 0.76 10.2 3.2 4.5 7.7 0.1 3.0 3 0 0 3 3 3 0 Nnf1 Asp PF00026.23 KIY49197.1 - 3.6e-30 105.5 0.4 1.4e-28 100.2 0.4 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY49197.1 - 0.025 14.8 0.1 0.025 14.8 0.1 2.8 3 1 0 4 4 4 0 Xylanase inhibitor N-terminal stn_TNFRSF12A PF12191.8 KIY49197.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Fe-ADH PF00465.19 KIY49198.1 - 3.3e-87 292.7 0.0 4.8e-87 292.1 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIY49198.1 - 1.1e-10 41.6 0.0 6.6e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Stealth_CR1 PF17101.5 KIY49199.1 - 1.1 9.0 4.2 3.4 7.5 4.2 1.9 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 TFIIF_alpha PF05793.12 KIY49200.1 - 1e-05 24.4 50.7 0.042 12.4 0.0 3.7 2 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Polysacc_deac_1 PF01522.21 KIY49201.1 - 2.6e-26 91.9 0.0 5e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.25 KIY49204.1 - 1.1e-69 234.7 0.0 1.7e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49204.1 - 4.6e-47 160.5 0.0 7.1e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY49204.1 - 0.00033 19.5 0.0 0.00074 18.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY49204.1 - 0.00077 18.9 0.0 0.0023 17.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY49204.1 - 0.019 14.9 0.0 5.9 6.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family HLH PF00010.26 KIY49205.1 - 3.5e-12 46.1 0.7 3.8e-12 46.0 0.7 1.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA PF00004.29 KIY49206.1 - 0.00012 22.5 0.0 0.00012 22.5 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KIY49206.1 - 0.016 15.2 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KIY49206.1 - 0.016 15.1 0.0 0.017 15.1 0.0 1.0 1 0 0 1 1 1 0 Rad17 P-loop domain TIP49 PF06068.13 KIY49206.1 - 0.021 14.0 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 KIY49206.1 - 0.025 14.9 0.0 0.025 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KIY49206.1 - 0.03 14.0 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KIY49206.1 - 0.051 13.6 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KIY49206.1 - 0.06 12.4 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KIY49206.1 - 0.082 12.4 0.0 0.097 12.2 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 KIY49206.1 - 0.2 11.4 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Exo_endo_phos PF03372.23 KIY49207.1 - 1.3e-15 57.5 0.0 4.4e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KIY49207.1 - 7e-06 26.0 2.7 0.00025 21.1 0.0 2.6 2 0 0 2 2 2 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 KIY49207.1 - 0.0023 17.7 0.0 0.4 10.5 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase acVLRF1 PF18859.1 KIY49207.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor RNHCP PF12647.7 KIY49207.1 - 0.14 12.2 0.0 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 RNHCP domain DUF1730 PF08331.10 KIY49207.1 - 0.14 12.1 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) RFX_DNA_binding PF02257.15 KIY49208.1 - 1.3e-27 96.2 0.1 2.7e-27 95.2 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Cu-oxidase_2 PF07731.14 KIY49208.1 - 0.047 13.4 0.3 0.091 12.5 0.3 1.4 1 0 0 1 1 1 0 Multicopper oxidase WD40 PF00400.32 KIY49209.1 - 0.00045 21.0 10.8 1.1 10.2 0.8 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY49209.1 - 0.0013 19.0 0.2 0.045 14.0 0.0 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIY49209.1 - 0.07 11.6 0.0 0.15 10.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF4407 PF14362.6 KIY49210.1 - 7.6e-05 22.2 16.2 7.6e-05 22.2 16.2 3.7 1 1 3 4 4 4 1 Domain of unknown function (DUF4407) DUF3417 PF11897.8 KIY49210.1 - 0.035 14.6 0.9 0.035 14.6 0.9 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3417) DUF5624 PF18538.1 KIY49210.1 - 1.1 9.3 4.2 1.5 8.9 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5624) HsbA PF12296.8 KIY49210.1 - 1.2 9.6 9.6 6 7.3 2.7 3.6 3 1 1 4 4 4 0 Hydrophobic surface binding protein A APG6_N PF17675.1 KIY49210.1 - 4 8.0 36.2 0.37 11.3 14.3 3.9 2 1 2 4 4 4 0 Apg6 coiled-coil region Prominin PF05478.11 KIY49210.1 - 4.1 5.2 6.8 8.9 4.1 6.8 1.6 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 KIY49210.1 - 4.3 7.4 5.7 15 5.6 0.6 3.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 KIY49211.1 - 1.4e-19 70.3 42.6 1.6e-19 70.1 36.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PCI PF01399.27 KIY49212.1 - 7.5e-12 45.7 0.0 2.5e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 PCI domain PUB PF09409.10 KIY49215.1 - 2e-13 50.0 0.0 2.9e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 PUB domain PEN-2 PF10251.9 KIY49216.1 - 0.11 12.9 0.9 4 7.9 0.1 2.2 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Baculo_11_kDa PF06143.11 KIY49216.1 - 0.56 9.8 3.7 1 9.0 3.7 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family UL45 PF05473.12 KIY49216.1 - 3.4 7.3 5.2 15 5.1 0.4 2.1 1 1 1 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF3336 PF11815.8 KIY49217.1 - 1.3e-44 151.3 0.4 1.9e-44 150.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KIY49217.1 - 2.7e-13 50.6 0.3 1.4e-12 48.2 0.3 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF3759 PF12585.8 KIY49218.1 - 1.6e-37 127.4 9.3 1.8e-37 127.2 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) ORC4_C PF14629.6 KIY49219.1 - 1.1e-21 77.2 0.0 1.9e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KIY49219.1 - 7.4e-16 59.0 0.2 2.6e-15 57.2 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KIY49219.1 - 0.00032 21.1 0.0 0.05 14.0 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIY49219.1 - 0.00087 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KIY49219.1 - 0.0056 16.4 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KIY49219.1 - 0.0066 16.5 0.0 0.023 14.7 0.0 1.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KIY49219.1 - 0.0076 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIY49219.1 - 0.02 14.8 0.0 0.068 13.1 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KIY49219.1 - 0.044 13.0 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 KIY49219.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KIY49219.1 - 0.08 12.9 0.0 7.3 6.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RNA12 PF10443.9 KIY49219.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein AAA_22 PF13401.6 KIY49219.1 - 0.094 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIY49219.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KIY49219.1 - 0.17 11.6 0.0 0.84 9.4 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KIY49219.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Med20 PF08612.11 KIY49221.1 - 7.6e-09 35.3 0.0 5.1e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex GGACT PF06094.12 KIY49222.1 - 2.8e-12 47.3 0.0 4.2e-12 46.7 0.0 1.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF2197 PF09963.9 KIY49222.1 - 0.03 14.6 0.0 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Pkinase PF00069.25 KIY49223.1 - 2.4e-64 217.3 0.3 3.4e-43 147.9 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49223.1 - 1e-29 103.6 0.2 2.9e-21 75.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY49223.1 - 3.7e-07 29.4 0.1 5.1e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY49223.1 - 0.00027 20.4 0.6 0.001 18.5 0.0 2.1 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY49223.1 - 0.00063 19.2 0.2 0.0048 16.3 0.1 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KIY49223.1 - 0.0023 17.9 3.6 0.038 13.9 0.5 2.8 1 1 2 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY49223.1 - 0.024 14.3 0.5 0.06 12.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KIY49223.1 - 0.039 12.7 0.5 0.058 12.2 0.5 1.4 1 1 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KIY49223.1 - 0.054 12.5 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 KIY49223.1 - 0.059 12.4 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 KIY49223.1 - 0.26 12.0 3.5 0.41 11.4 2.4 2.0 2 0 0 2 2 2 0 Protein kinase C terminal domain BCDHK_Adom3 PF10436.9 KIY49224.1 - 5e-40 137.0 0.3 4e-38 130.8 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIY49224.1 - 4.9e-06 27.0 0.0 0.00013 22.4 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIY49224.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FmiP_Thoc5 PF09766.9 KIY49226.1 - 1.1e-29 103.9 11.7 1.4e-29 103.6 11.7 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 LON_substr_bdg PF02190.16 KIY49227.1 - 1e-18 68.0 0.0 1.5e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KIY49227.1 - 2.5e-18 65.6 25.1 1.5e-12 47.1 14.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY49227.1 - 7.4e-14 51.5 23.0 5.5e-09 35.9 8.3 3.3 2 1 1 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 KIY49227.1 - 3e-13 49.5 21.2 1.5e-07 31.2 11.2 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIY49227.1 - 1.2e-12 47.8 21.4 1.1e-06 28.7 10.4 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIY49227.1 - 2.1e-12 46.7 23.2 6.8e-07 29.1 13.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY49227.1 - 3.9e-12 45.8 19.3 2.5e-08 33.6 8.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY49227.1 - 9.8e-11 41.8 26.2 2.7e-08 34.0 12.4 2.7 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 KIY49227.1 - 4.7e-08 32.8 23.2 1e-06 28.4 9.0 2.9 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KIY49227.1 - 5.9e-06 26.3 5.8 5.9e-06 26.3 5.8 2.5 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 KIY49227.1 - 0.0013 18.9 1.1 0.048 13.8 0.0 2.4 2 0 0 2 2 2 1 U-box domain zf-rbx1 PF12678.7 KIY49227.1 - 0.0032 17.7 6.9 0.0032 17.7 6.9 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KIY49227.1 - 0.0043 16.9 1.6 0.0043 16.9 1.6 2.5 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-P11 PF03854.14 KIY49227.1 - 0.0079 15.8 7.6 0.0079 15.8 7.6 2.8 3 0 0 3 3 3 1 P-11 zinc finger zf-RING_4 PF14570.6 KIY49227.1 - 0.08 12.7 15.8 0.081 12.7 6.8 3.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 KIY49227.1 - 0.13 12.8 3.8 2.3 8.8 0.2 3.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 KIY49227.1 - 0.47 10.3 5.3 4.4 7.2 0.7 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 KIY49227.1 - 1.2 8.9 14.5 6 6.7 0.6 3.1 2 1 0 2 2 2 0 RING-like zinc finger zinc_ribbon_16 PF17034.5 KIY49227.1 - 1.4 9.1 10.4 0.3 11.3 2.1 2.7 2 1 0 2 2 2 0 Zinc-ribbon like family DUF1272 PF06906.11 KIY49227.1 - 1.9 8.6 9.1 0.8 9.8 5.7 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) zf-WRNIP1_ubi PF18279.1 KIY49227.1 - 4.6 8.1 8.0 1.3 9.8 0.1 3.8 4 0 0 4 4 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF1682 PF07946.14 KIY49228.1 - 1.5e-91 307.0 0.9 1.7e-91 306.8 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Cgr1 PF03879.14 KIY49228.1 - 0.94 9.9 19.8 1.5 9.2 19.8 1.2 1 0 0 1 1 1 0 Cgr1 family G6PD_C PF02781.16 KIY49230.1 - 5.1e-104 347.5 0.0 6.7e-104 347.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KIY49230.1 - 6.4e-52 176.7 0.1 1.1e-51 176.0 0.1 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3818 PF12825.7 KIY49231.1 - 8.6e-133 442.5 0.5 1.3e-132 441.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KIY49231.1 - 1.5e-34 118.7 0.5 4.6e-34 117.2 0.5 1.9 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KIY49231.1 - 1e-09 38.4 0.0 2.9e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 PX domain TPR_7 PF13176.6 KIY49231.1 - 0.077 13.1 0.1 0.36 11.0 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Lin-8 PF03353.15 KIY49231.1 - 0.14 11.7 3.8 0.32 10.5 3.8 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4637 PF15470.6 KIY49231.1 - 0.41 10.4 4.0 1.1 9.0 4.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BUD22 PF09073.10 KIY49231.1 - 0.65 9.3 8.6 1.6 8.0 8.6 1.7 1 0 0 1 1 1 0 BUD22 Imm2 PF14426.6 KIY49231.1 - 2.7 8.1 5.3 7.8 6.6 1.7 3.4 4 0 0 4 4 4 0 Immunity protein Imm2 UQ_con PF00179.26 KIY49232.1 - 6.3e-39 132.8 0.1 7.6e-39 132.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY49232.1 - 0.055 13.8 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain HSBP1 PF06825.12 KIY49233.1 - 1.7e-19 69.4 4.4 2.3e-19 69.0 4.4 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 KIY49233.1 - 0.012 15.7 0.2 0.016 15.3 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FdhE PF04216.12 KIY49233.1 - 0.025 14.5 0.0 0.028 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation NPV_P10 PF05531.12 KIY49233.1 - 0.043 14.3 1.1 0.088 13.3 1.1 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EspB PF05802.11 KIY49233.1 - 0.047 13.7 0.1 0.056 13.4 0.1 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Ribosomal_L7Ae PF01248.26 KIY49235.1 - 3.2e-26 90.9 1.0 4.2e-26 90.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.32 KIY49236.1 - 9.9e-16 57.9 11.3 8e-08 32.8 0.3 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY49236.1 - 0.0062 16.8 0.0 0.043 14.1 0.0 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KIY49237.1 - 2.2e-76 256.7 0.0 2.6e-76 256.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49237.1 - 6.9e-39 133.7 0.0 9.1e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY49237.1 - 4.4e-07 29.5 0.1 3.8e-06 26.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KIY49237.1 - 1.5e-06 27.4 0.1 2.9e-05 23.2 0.1 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KIY49237.1 - 0.0046 16.4 0.2 0.011 15.1 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM72 PF16054.5 KIY49237.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 72 Pkinase_fungal PF17667.1 KIY49237.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 KIY49238.1 - 0.0019 18.1 0.4 0.0049 16.7 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY49238.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 F-box Flavi_M PF01004.19 KIY49239.1 - 0.18 11.6 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M DUF1361 PF07099.11 KIY49241.1 - 0.27 11.2 0.0 0.27 11.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1361) MARVEL PF01284.23 KIY49241.1 - 0.29 11.2 18.7 3.7 7.6 19.7 2.0 1 1 1 2 2 2 0 Membrane-associating domain Jiraiya PF15038.6 KIY49241.1 - 0.44 10.0 12.1 0.16 11.4 4.5 2.6 1 1 1 2 2 2 0 Jiraiya AMP-binding PF00501.28 KIY49242.1 - 1.2e-31 109.8 0.0 1.7e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIY49242.1 - 3.2e-05 23.7 2.8 7.7e-05 22.5 2.8 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KIY49242.1 - 0.011 16.7 0.0 0.021 15.8 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Metallophos PF00149.28 KIY49244.1 - 9.2e-07 29.6 0.4 1.9e-06 28.6 0.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Med17 PF10156.9 KIY49245.1 - 2.3e-32 112.3 0.0 2.8e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex RRM_1 PF00076.22 KIY49246.1 - 3.2e-14 52.5 0.1 6.5e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp PF00026.23 KIY49248.1 - 3.4e-110 368.4 0.7 4e-110 368.1 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY49248.1 - 1.2e-15 58.2 1.2 2.1e-13 50.9 1.4 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY49248.1 - 4.2e-05 24.1 0.0 0.11 13.1 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KIY49248.1 - 0.00032 20.5 0.0 0.0033 17.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KIY49248.1 - 0.00083 19.9 0.0 1.6 9.3 0.0 2.6 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease DUF3925 PF13063.6 KIY49248.1 - 0.1 12.8 0.3 0.77 10.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3925) Thioredoxin PF00085.20 KIY49249.1 - 3.2e-56 187.7 0.0 1.2e-29 102.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KIY49249.1 - 5.5e-39 134.0 0.0 1.3e-30 106.7 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIY49249.1 - 4.3e-06 26.8 0.2 0.014 15.5 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KIY49249.1 - 1.4e-05 25.0 1.2 0.099 12.6 0.0 3.2 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.17 KIY49249.1 - 3e-05 23.2 0.5 0.00013 21.2 0.1 2.0 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.6 KIY49249.1 - 8.6e-05 22.8 0.4 0.54 10.6 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KIY49249.1 - 0.00017 22.0 0.5 0.42 11.1 0.2 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Redoxin PF08534.10 KIY49249.1 - 0.12 12.1 0.9 16 5.2 0.0 2.9 3 0 0 3 3 3 0 Redoxin Glutaredoxin PF00462.24 KIY49249.1 - 0.23 11.7 1.1 11 6.4 0.0 2.8 2 1 0 2 2 2 0 Glutaredoxin GCP_N_terminal PF17681.1 KIY49250.1 - 2.1e-97 326.5 0.0 4.6e-97 325.4 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIY49250.1 - 1.4e-90 304.0 0.4 3.2e-90 302.7 0.4 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal FAT PF02259.23 KIY49251.1 - 4.5e-66 223.4 0.8 1.1e-65 222.2 0.8 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KIY49251.1 - 6.4e-22 78.6 0.0 3.5e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase CTNNBL PF08216.11 KIY49252.1 - 7.5e-35 119.2 0.0 2.2e-34 117.7 0.0 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear LemA PF04011.12 KIY49252.1 - 0.042 13.7 0.2 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 LemA family Exo70 PF03081.15 KIY49252.1 - 0.057 12.5 0.1 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Arm PF00514.23 KIY49252.1 - 0.23 11.6 0.5 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KIY49252.1 - 4.1 7.1 6.6 0.68 9.5 0.4 2.7 3 0 0 3 3 3 0 Atypical Arm repeat UTP15_C PF09384.10 KIY49253.1 - 2.9e-50 169.8 0.1 4.3e-50 169.2 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KIY49253.1 - 7.7e-23 80.4 5.6 5e-05 24.0 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY49253.1 - 9e-09 35.5 0.0 0.00027 21.2 0.0 4.5 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIY49253.1 - 0.0078 14.8 0.1 0.77 8.2 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_3 PF13570.6 KIY49253.1 - 0.041 14.4 1.5 0.47 11.0 0.1 2.9 3 0 0 3 3 3 0 PQQ-like domain PQQ PF01011.21 KIY49253.1 - 0.14 12.2 0.1 0.58 10.2 0.1 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat TCTP PF00838.17 KIY49254.1 - 3.7e-75 251.8 1.5 4.2e-75 251.7 1.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein WH2 PF02205.20 KIY49255.1 - 9.4e-07 28.5 1.2 2.7e-06 27.0 0.6 2.1 2 0 0 2 2 2 1 WH2 motif Ribosomal_L5e PF17144.4 KIY49257.1 - 4e-81 270.8 0.1 6.4e-81 270.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KIY49257.1 - 2.2e-33 115.0 1.3 2.2e-33 115.0 1.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Snf7 PF03357.21 KIY49259.1 - 9.1e-29 100.2 17.3 9.1e-29 100.2 17.3 1.4 1 1 0 1 1 1 1 Snf7 LUC7 PF03194.15 KIY49259.1 - 0.011 15.5 4.7 0.011 15.5 4.7 1.7 1 1 1 2 2 2 0 LUC7 N_terminus E2F_CC-MB PF16421.5 KIY49259.1 - 0.084 13.2 2.5 0.4 11.1 0.7 2.6 2 1 1 3 3 3 0 E2F transcription factor CC-MB domain Acyl-CoA_dh_C PF12806.7 KIY49259.1 - 0.12 12.5 4.8 5.4 7.2 4.8 2.6 1 1 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Atg14 PF10186.9 KIY49259.1 - 2.8 6.9 6.3 4.8 6.2 6.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med22 PF06179.12 KIY49259.1 - 3.8 7.8 9.1 0.76 10.0 3.0 2.5 3 0 0 3 3 3 0 Surfeit locus protein 5 subunit 22 of Mediator complex RNB PF00773.19 KIY49261.1 - 1.3e-99 333.7 0.6 2.8e-99 332.5 0.0 1.9 2 0 0 2 2 2 1 RNB domain Dis3l2_C_term PF17877.1 KIY49261.1 - 3e-25 88.4 0.2 9.5e-25 86.8 0.2 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KIY49261.1 - 8e-25 86.7 0.0 2.4e-24 85.2 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KIY49261.1 - 5.1e-05 23.4 0.1 0.038 14.2 0.0 3.1 3 0 0 3 3 3 2 Cold shock domain Rrp44_S1 PF17215.3 KIY49261.1 - 0.00095 19.1 1.3 0.0021 18.0 0.0 2.3 2 1 1 3 3 3 1 S1 domain Rrp44_CSD1 PF17216.3 KIY49261.1 - 0.0098 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain DUF4847 PF16139.5 KIY49261.1 - 0.12 12.3 0.2 0.34 10.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4847) Iso_dh PF00180.20 KIY49262.1 - 7.5e-100 334.5 0.0 9.2e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.18 KIY49263.1 - 3.9e-18 65.4 0.0 5.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMG_box PF00505.19 KIY49264.1 - 1.1e-07 32.1 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DUF936 PF06075.12 KIY49264.1 - 0.014 14.4 8.0 0.019 13.9 8.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FAM60A PF15396.6 KIY49264.1 - 1.2 9.1 7.9 1.9 8.4 7.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Hydin_ADK PF17213.3 KIY49264.1 - 2 8.6 6.1 3.4 7.9 6.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RR_TM4-6 PF06459.12 KIY49264.1 - 6.8 6.4 8.1 11 5.8 8.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NTS_2 PF15448.6 KIY49264.1 - 9 6.8 6.8 0.41 11.1 0.6 2.0 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein GFA PF04828.14 KIY49265.1 - 5.5e-09 36.2 0.5 1.3e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 KIY49265.1 - 0.099 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glyco_transf_22 PF03901.17 KIY49266.1 - 2.2e-81 274.2 15.3 5.1e-81 273.0 15.3 1.5 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3493 PF11998.8 KIY49266.1 - 0.2 11.9 3.4 0.38 10.9 0.7 2.5 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Ribosomal_L36e PF01158.18 KIY49267.1 - 8.7e-39 131.7 3.3 9.6e-39 131.5 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.7 KIY49267.1 - 0.049 13.2 0.1 0.062 12.8 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF2207 PF09972.9 KIY49267.1 - 0.078 11.7 0.1 0.081 11.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CK_II_beta PF01214.18 KIY49268.1 - 2e-74 249.3 0.0 2.5e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit YL1 PF05764.13 KIY49268.1 - 0.0039 17.4 3.0 0.0052 16.9 3.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 KIY49268.1 - 0.088 12.2 4.1 0.12 11.8 4.1 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KIY49268.1 - 0.77 9.0 6.8 1 8.6 6.8 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 KIY49268.1 - 0.99 8.9 5.0 1.4 8.4 5.0 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KIY49268.1 - 1.2 7.3 6.1 1.4 7.0 6.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KIY49268.1 - 1.4 7.1 3.7 2 6.6 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Prothymosin PF03247.14 KIY49268.1 - 1.5 9.3 15.5 2.6 8.5 15.5 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family CobT PF06213.12 KIY49268.1 - 3.5 6.9 9.5 5 6.4 9.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT adh_short PF00106.25 KIY49269.1 - 1.9e-25 89.5 0.0 2.5e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY49269.1 - 8.4e-12 45.1 0.0 1.2e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY49269.1 - 4.6e-07 29.9 0.0 7.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY49269.1 - 0.00079 18.9 0.0 0.0016 17.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KIY49269.1 - 0.064 13.8 0.0 0.19 12.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 KIY49269.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 KIY49269.1 - 0.15 12.0 0.4 0.29 11.0 0.4 1.6 1 1 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIY49269.1 - 0.16 11.0 0.0 0.62 9.1 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain CRCB PF02537.15 KIY49270.1 - 3.7e-33 113.7 18.2 9.1e-20 70.8 8.3 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Yae1_N PF09811.9 KIY49272.1 - 2.6e-11 43.0 6.8 3.4e-11 42.6 6.8 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal VID27 PF08553.10 KIY49273.1 - 5.3e-160 532.3 0.0 7.9e-160 531.7 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KIY49273.1 - 1e-56 191.5 0.2 1e-56 191.5 0.2 3.3 2 1 1 3 3 3 2 VID27 N-terminal region VID27_PH PF17747.1 KIY49273.1 - 9.8e-24 83.7 4.8 2.5e-23 82.4 4.8 1.7 1 0 0 1 1 1 1 VID27 PH-like domain KNOX2 PF03791.13 KIY49273.1 - 0.093 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 KNOX2 domain Drc1-Sld2 PF11719.8 KIY49273.1 - 0.44 10.0 5.3 0.75 9.3 5.3 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein RTA1 PF04479.13 KIY49274.1 - 6.6e-55 185.9 10.0 6.6e-55 185.9 10.0 1.4 2 0 0 2 2 2 1 RTA1 like protein LytTR PF04397.15 KIY49274.1 - 0.064 13.5 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 LytTr DNA-binding domain DUF2254 PF10011.9 KIY49274.1 - 2.5 6.8 8.2 11 4.8 0.5 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2254) DUF4131 PF13567.6 KIY49274.1 - 4.7 6.8 17.6 0.27 10.9 3.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Iso_dh PF00180.20 KIY49276.1 - 8.1e-78 262.0 0.0 9.2e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF262 PF03235.14 KIY49278.1 - 5.8e-14 52.8 0.1 1.3e-13 51.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF262 NLRC4_HD2 PF17776.1 KIY49278.1 - 0.11 13.1 0.0 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 NLRC4 helical domain HD2 DUF4303 PF14136.6 KIY49278.1 - 0.12 12.2 0.2 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) YoaP PF14268.6 KIY49278.1 - 0.15 11.6 0.1 0.37 10.4 0.1 1.5 1 0 0 1 1 1 0 YoaP-like Dcc1 PF09724.9 KIY49279.1 - 4.2e-75 253.1 0.0 4.9e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Gln-synt_C PF00120.24 KIY49280.1 - 3.6e-16 59.1 0.0 2.7e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KIY49280.1 - 4.2e-12 45.6 0.0 7.5e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Clat_adaptor_s PF01217.20 KIY49281.1 - 6.7e-57 191.4 2.2 8e-57 191.2 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BTB_2 PF02214.22 KIY49282.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain Transket_pyr PF02779.24 KIY49283.1 - 1e-45 155.6 0.0 1.8e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIY49283.1 - 7.1e-40 135.7 0.0 1.6e-39 134.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KIY49283.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Histidinol_dh PF00815.20 KIY49284.1 - 8.9e-156 519.0 3.7 1.5e-155 518.2 3.7 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KIY49284.1 - 3.9e-24 84.3 0.0 1e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KIY49284.1 - 1.1e-11 45.1 0.3 2.8e-11 43.7 0.2 1.8 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Phage_TTP_13 PF16463.5 KIY49284.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein family TspO_MBR PF03073.15 KIY49285.1 - 9.1e-41 139.1 10.5 1.1e-40 138.9 10.5 1.0 1 0 0 1 1 1 1 TspO/MBR family TRAM_LAG1_CLN8 PF03798.16 KIY49286.1 - 1.1e-34 119.9 31.2 1.1e-34 119.9 31.2 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KIY49286.1 - 0.0038 16.9 2.2 0.012 15.3 2.2 1.9 1 0 0 1 1 1 1 TRAM1-like protein ArgoN PF16486.5 KIY49288.1 - 7.7e-14 52.5 0.0 8.8e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 N-terminal domain of argonaute HD_3 PF13023.6 KIY49289.1 - 0.21 11.5 0.7 0.42 10.5 0.3 1.7 2 0 0 2 2 2 0 HD domain Mito_carr PF00153.27 KIY49290.1 - 4.3e-62 206.1 5.8 6.2e-22 77.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KIY49290.1 - 0.00021 20.6 0.2 0.031 13.8 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KIY49290.1 - 0.00036 20.2 0.5 0.022 14.6 0.1 3.2 3 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KIY49290.1 - 0.00042 20.7 0.3 0.0012 19.3 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KIY49290.1 - 0.024 14.1 1.2 0.62 9.7 0.0 3.3 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 KIY49290.1 - 0.061 13.2 0.0 11 6.0 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair SNARE_assoc PF09335.11 KIY49291.1 - 9.4e-17 61.6 2.6 9.4e-17 61.6 2.6 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein Amidohydro_2 PF04909.14 KIY49292.1 - 2.9e-27 96.2 1.9 3.8e-27 95.8 1.9 1.1 1 0 0 1 1 1 1 Amidohydrolase Imm45 PF15572.6 KIY49292.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.7 1 1 0 1 1 1 0 Immunity protein 45 Histone PF00125.24 KIY49293.1 - 1.2e-41 142.2 0.3 1.5e-41 141.9 0.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIY49293.1 - 0.0017 18.4 0.1 0.0027 17.8 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KIY49293.1 - 0.0029 17.9 0.1 0.0045 17.3 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY49293.1 - 0.005 17.1 0.2 0.01 16.1 0.2 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 60KD_IMP PF02096.20 KIY49294.1 - 0.00022 21.2 0.2 0.00026 20.9 0.2 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_L6e PF01159.19 KIY49295.1 - 7.9e-36 123.0 0.0 1.2e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KIY49295.1 - 5e-05 23.5 1.3 5.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain Hydrolase PF00702.26 KIY49296.1 - 2.7e-11 44.1 0.0 9.1e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIY49296.1 - 1.5e-09 38.2 0.0 2.9e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY49296.1 - 0.00061 19.8 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like AAA PF00004.29 KIY49297.1 - 4e-14 53.2 0.1 1.3e-13 51.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 KIY49297.1 - 1e-10 41.5 0.0 2.6e-10 40.2 0.0 1.8 1 1 0 1 1 1 1 BAH domain AAA_16 PF13191.6 KIY49297.1 - 4.5e-09 36.9 0.0 1.9e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY49297.1 - 4.5e-06 27.0 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 KIY49297.1 - 1.3e-05 25.2 0.1 3.3e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 KIY49297.1 - 0.0017 18.7 0.1 0.0082 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KIY49297.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KIY49297.1 - 0.097 12.4 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KIY49297.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 KIY49297.1 - 0.27 11.0 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain LAP1C PF05609.12 KIY49297.1 - 2 7.4 10.5 3.5 6.6 10.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 KIY49297.1 - 4.4 5.3 8.5 6.9 4.7 8.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EB PF01683.18 KIY49298.1 - 8.2e-05 22.8 21.4 0.009 16.3 7.4 3.7 3 1 1 4 4 4 3 EB module PAF PF15715.5 KIY49298.1 - 0.29 11.7 1.1 0.29 11.7 0.0 1.6 2 0 0 2 2 2 0 PCNA-associated factor histone like domain Ran-binding PF05508.11 KIY49299.1 - 0.016 14.2 0.3 0.018 14.1 0.3 1.0 1 0 0 1 1 1 0 RanGTP-binding protein Pro-kuma_activ PF09286.11 KIY49300.1 - 1.3e-40 138.9 0.0 9.4e-40 136.2 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIY49300.1 - 1.4e-05 24.5 1.7 2.3e-05 23.8 1.7 1.2 1 0 0 1 1 1 1 Subtilase family DUF4346 PF14251.6 KIY49300.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) Atg29_N PF18388.1 KIY49301.1 - 2.5e-13 49.6 1.2 4.2e-13 48.9 1.2 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain DUF2985 PF11204.8 KIY49302.1 - 1.9e-16 59.9 1.8 2.1e-16 59.8 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Tmpp129 PF10272.9 KIY49302.1 - 0.043 13.1 0.0 0.083 12.2 0.0 1.4 2 0 0 2 2 2 0 Putative transmembrane protein precursor DUF3169 PF11368.8 KIY49302.1 - 0.063 12.8 0.9 0.73 9.3 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) SPC12 PF06645.13 KIY49302.1 - 0.63 10.2 4.5 2.4 8.3 0.1 3.3 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Apt1 PF10351.9 KIY49303.1 - 2e-83 280.9 1.3 3.2e-83 280.2 1.3 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KIY49303.1 - 3.9e-43 148.0 0.0 8.4e-43 146.9 0.0 1.5 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KIY49303.1 - 1.3e-37 129.3 0.0 2.8e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KIY49303.1 - 9e-29 100.4 0.0 2.7e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KIY49303.1 - 1.4e-21 77.1 0.0 4e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Lip_prot_lig_C PF10437.9 KIY49303.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus ADH_N PF08240.12 KIY49304.1 - 1e-21 76.9 0.3 2e-21 75.9 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY49304.1 - 2.5e-20 72.8 0.5 4.2e-20 72.1 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY49304.1 - 7.5e-06 27.0 0.0 1.5e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY49304.1 - 1.3e-05 24.8 0.2 0.00071 19.1 0.2 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Methyltransf_25 PF13649.6 KIY49304.1 - 0.00052 20.7 0.0 0.00095 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KIY49304.1 - 0.003 17.1 0.1 0.0052 16.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_12 PF08242.12 KIY49304.1 - 0.0071 17.1 0.0 0.013 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY49304.1 - 0.0089 15.8 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY49304.1 - 0.032 14.9 0.0 0.06 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIY49304.1 - 0.1 12.1 0.1 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain EIAV_GP90 PF00971.18 KIY49304.1 - 0.2 10.3 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 Pkinase PF00069.25 KIY49305.1 - 2.4e-54 184.5 0.0 2.9e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49305.1 - 8.4e-34 117.0 0.0 1e-33 116.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY49305.1 - 4.6e-05 22.9 0.0 0.00041 19.8 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KIY49305.1 - 5e-05 23.3 0.0 0.0027 17.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY49305.1 - 0.0032 16.9 0.1 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KIY49305.1 - 0.0051 16.4 0.1 0.0095 15.5 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase PPK2 PF03976.14 KIY49305.1 - 0.0053 16.3 0.0 0.0071 15.9 0.0 1.1 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) Pox_ser-thr_kin PF05445.11 KIY49305.1 - 0.042 12.8 0.2 0.058 12.4 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 KIY49305.1 - 0.055 13.0 0.2 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Spuma_A9PTase PF03539.14 KIY49305.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Meth_synt_2 PF01717.18 KIY49306.1 - 8.3e-149 495.2 0.0 8.4e-146 485.3 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIY49306.1 - 4.2e-112 374.7 0.0 4.1e-106 355.0 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain DNA_pol_E_B PF04042.16 KIY49307.1 - 3.9e-44 150.5 0.2 5.3e-44 150.1 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KIY49307.1 - 0.018 15.2 0.0 0.079 13.1 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain SNase PF00565.17 KIY49308.1 - 3.5e-58 194.7 0.0 8.2e-20 71.3 0.0 6.2 6 0 0 6 6 6 6 Staphylococcal nuclease homologue TUDOR PF00567.24 KIY49308.1 - 1.7e-20 73.3 0.0 4.2e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KIY49308.1 - 0.0089 16.5 0.2 0.24 11.9 0.0 3.1 3 0 0 3 3 3 1 Agenet domain IBR PF01485.21 KIY49309.1 - 9e-15 54.6 30.4 6.5e-08 32.7 6.5 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KIY49309.1 - 1.3e-07 31.5 4.9 1.3e-07 31.5 4.9 3.3 3 2 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY49309.1 - 1.3e-07 31.6 4.0 1.3e-07 31.6 4.0 4.1 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIY49309.1 - 1.3e-05 24.9 5.0 1.3e-05 24.9 5.0 4.2 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY49309.1 - 1.5e-05 24.7 2.0 1.5e-05 24.7 2.0 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY49309.1 - 4.4e-05 23.7 2.9 4.4e-05 23.7 2.9 4.1 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY49309.1 - 0.00058 19.7 3.1 0.00058 19.7 3.1 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KIY49309.1 - 0.091 12.6 0.0 0.66 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.29 KIY49309.1 - 0.11 12.3 0.5 4 7.3 0.0 3.5 4 0 0 4 4 4 0 KH domain zf-ribbon_3 PF13248.6 KIY49309.1 - 6.2 6.4 10.9 1 8.8 0.1 4.0 3 0 0 3 3 3 0 zinc-ribbon domain Ribosomal_L6 PF00347.23 KIY49310.1 - 6.9e-27 93.9 1.9 1.4e-15 57.7 0.6 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 RACo_C_ter PF14574.6 KIY49310.1 - 0.062 12.3 0.2 0.18 10.8 0.1 1.7 1 1 0 2 2 2 0 C-terminal domain of RACo the ASKHA domain Fungal_trans PF04082.18 KIY49311.1 - 6.7e-10 38.4 0.7 1.9e-09 36.9 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1221 PF06760.11 KIY49311.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) OMPdecase PF00215.24 KIY49312.1 - 1e-71 241.1 0.0 1.2e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TruD PF01142.18 KIY49313.1 - 6.1e-78 262.5 0.0 5.6e-76 256.0 0.0 2.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF5320 PF17253.2 KIY49313.1 - 0.00041 21.4 3.0 0.2 12.8 0.0 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF5320) FoP_duplication PF13865.6 KIY49313.1 - 0.52 10.9 23.2 0.11 13.0 9.3 3.1 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.16 KIY49314.1 - 4.2e-35 121.3 31.1 1e-33 116.7 24.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KIY49314.1 - 0.00019 20.5 0.2 0.00037 19.5 0.2 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 KIY49314.1 - 0.0017 16.8 1.7 0.0028 16.2 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly_transf_sug PF04488.15 KIY49315.1 - 1.4e-20 73.7 0.1 3.1e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KIY49315.1 - 0.077 12.3 0.4 0.17 11.2 0.4 1.5 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 KIY49315.1 - 0.14 11.5 0.4 0.2 11.0 0.4 1.5 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein PIN_4 PF13638.6 KIY49316.1 - 6.6e-21 75.0 0.1 1.4e-20 73.9 0.1 1.5 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KIY49316.1 - 0.02 15.4 0.0 0.052 14.0 0.0 1.7 2 0 0 2 2 2 0 PIN domain PIN_8 PF18476.1 KIY49316.1 - 0.04 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 PIN like domain DUF4411 PF14367.6 KIY49316.1 - 0.069 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Zn-C2H2_12 PF18112.1 KIY49317.1 - 2.7e-06 27.7 3.4 0.025 15.0 0.7 2.5 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 KIY49317.1 - 0.00023 21.4 0.5 0.003 17.8 0.1 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding BIR PF00653.21 KIY49317.1 - 0.013 16.1 2.7 0.07 13.8 0.6 2.3 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2_6 PF13912.6 KIY49317.1 - 0.17 11.9 5.3 0.9 9.6 1.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Ntox1 PF15500.6 KIY49317.1 - 0.23 11.8 1.9 0.59 10.5 1.4 1.8 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 CFIA_Pcf11 PF11526.8 KIY49317.1 - 0.24 11.9 7.1 0.76 10.3 0.1 2.6 2 1 1 3 3 3 0 Subunit of cleavage factor IA Pcf11 zf-H2C2_2 PF13465.6 KIY49317.1 - 0.84 10.2 5.6 2.6 8.6 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY49317.1 - 2.4 9.2 12.9 3.6 8.7 0.4 3.5 4 1 0 4 4 4 0 C2H2-type zinc finger zf_UBZ PF18439.1 KIY49317.1 - 7.9 6.2 9.0 9.2 6.0 0.2 3.0 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger CTD_bind PF04818.13 KIY49318.1 - 2e-05 25.3 0.0 3.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Herpeto_peptide PF14409.6 KIY49318.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon ICMT PF04140.14 KIY49320.1 - 3e-26 91.7 0.9 3e-26 91.7 0.9 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY49320.1 - 5e-12 46.1 1.7 5e-12 46.1 1.7 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KIY49320.1 - 0.00042 19.9 1.3 0.00042 19.9 1.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) GTP_EFTU PF00009.27 KIY49321.1 - 4.1e-51 173.3 0.0 6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIY49321.1 - 3.2e-14 52.7 0.0 9.6e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.6 KIY49321.1 - 5.7e-14 52.0 0.0 1.5e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KIY49321.1 - 1.5e-07 31.7 0.0 3.4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY49321.1 - 0.00018 21.6 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIY49321.1 - 0.036 13.5 0.0 0.097 12.1 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RF3_C PF16658.5 KIY49321.1 - 0.042 13.7 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Acetyltransf_1 PF00583.25 KIY49323.1 - 6.7e-11 42.4 0.1 1.2e-10 41.6 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY49323.1 - 2.3e-09 37.3 0.0 9.6e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY49323.1 - 3.5e-08 33.8 0.1 6.8e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY49323.1 - 0.00019 21.3 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KIY49323.1 - 0.0026 17.5 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIY49323.1 - 0.0049 17.0 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KIY49323.1 - 0.005 17.5 0.3 0.043 14.5 0.3 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIY49323.1 - 0.016 15.3 0.0 0.07 13.3 0.0 1.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF2189 PF09955.9 KIY49325.1 - 0.047 13.9 0.1 0.047 13.9 0.1 3.3 3 1 0 3 3 3 0 Predicted integral membrane protein (DUF2189) MFS_2 PF13347.6 KIY49325.1 - 0.18 10.3 15.5 0.014 14.0 4.7 2.9 2 1 0 2 2 2 0 MFS/sugar transport protein Ribonuc_L-PSP PF01042.21 KIY49326.1 - 5.7e-17 61.9 0.0 3.7e-07 30.2 0.0 3.1 3 1 0 3 3 3 2 Endoribonuclease L-PSP Diphthami_syn_2 PF01902.17 KIY49326.1 - 4.9e-06 26.2 0.0 3.5e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Diphthamide synthase tRNA_synthFbeta PF17759.1 KIY49327.1 - 3.2e-49 167.3 0.0 5e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KIY49327.1 - 1.2e-32 111.9 0.0 1.7e-31 108.2 0.0 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KIY49327.1 - 1.1e-26 93.6 0.0 1.9e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KIY49327.1 - 7.7e-16 58.2 0.0 4.3e-13 49.3 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetase B5 domain SRP-alpha_N PF04086.13 KIY49329.1 - 0.042 13.8 3.2 0.046 13.7 3.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2370 PF10176.9 KIY49330.1 - 2.9e-74 249.5 0.0 4.9e-74 248.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF4064 PF13273.6 KIY49330.1 - 0.13 12.5 0.5 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Wtap PF17098.5 KIY49331.1 - 2.5e-14 53.5 7.0 1.2e-11 44.7 7.0 2.2 1 1 0 1 1 1 1 WTAP/Mum2p family DUF5614 PF18474.1 KIY49331.1 - 0.049 12.9 0.5 0.079 12.3 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5614) TMF_DNA_bd PF12329.8 KIY49331.1 - 0.085 12.9 4.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 KIY49331.1 - 0.091 12.6 3.7 3.7 7.5 0.0 2.9 2 2 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Hemerythrin PF01814.23 KIY49331.1 - 0.12 13.0 0.2 0.83 10.3 0.4 2.0 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain WD40_alt PF14077.6 KIY49331.1 - 2.5 8.0 4.6 38 4.3 0.4 3.3 3 0 0 3 3 3 0 Alternative WD40 repeat motif SKA1 PF07160.12 KIY49331.1 - 3.2 7.5 6.6 1.8 8.4 3.5 2.1 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Herpes_DNAp_acc PF04929.12 KIY49331.1 - 6.4 5.6 5.8 9.2 5.1 5.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Zn_ribbon_SprT PF17283.2 KIY49332.1 - 0.0071 16.2 1.1 2.3 8.2 0.0 2.3 2 0 0 2 2 2 2 SprT-like zinc ribbon domain Ank_4 PF13637.6 KIY49333.1 - 2.5e-24 85.3 7.5 1.5e-12 47.8 0.2 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY49333.1 - 6.2e-24 84.4 0.1 1.6e-15 57.5 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY49333.1 - 4.7e-18 65.0 0.2 1.9e-09 37.6 0.2 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY49333.1 - 7.7e-16 56.6 0.1 0.00015 21.9 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KIY49333.1 - 2.8e-14 52.8 0.1 2.4e-05 24.5 0.0 4.8 5 1 0 5 5 5 2 Ankyrin repeat Glyco_hydro_18 PF00704.28 KIY49336.1 - 4e-56 191.0 0.1 4.6e-56 190.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4965 PF16335.5 KIY49337.1 - 1.4e-74 249.5 1.1 2.5e-74 248.7 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KIY49337.1 - 2.2e-73 246.8 8.2 4.3e-73 245.9 8.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KIY49337.1 - 2.6e-68 229.7 4.1 2.6e-68 229.7 4.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIY49337.1 - 4.8e-06 26.0 0.1 1.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) FAD_binding_7 PF03441.14 KIY49338.1 - 6.5e-74 247.8 0.2 1.2e-73 247.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KIY49338.1 - 6.4e-37 127.1 0.0 1.7e-36 125.7 0.0 1.7 1 0 0 1 1 1 1 DNA photolyase eRF1_1 PF03463.15 KIY49339.1 - 1.3e-45 154.6 0.2 1.9e-45 154.0 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KIY49339.1 - 1.4e-22 80.3 0.0 3.1e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KIY49339.1 - 2.9e-15 56.8 0.0 4.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Phosducin PF02114.16 KIY49340.1 - 0.00018 20.5 0.1 0.00021 20.3 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KIY49340.1 - 0.017 15.1 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin PBP5_C PF07943.13 KIY49340.1 - 0.13 12.5 0.0 0.57 10.5 0.0 1.8 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain ThrE PF06738.12 KIY49341.1 - 4.6e-43 147.3 20.5 6.1e-43 146.9 5.8 2.4 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY49341.1 - 1.4e-05 25.3 7.5 1.4e-05 25.3 7.5 3.0 3 1 0 3 3 3 2 Threonine/Serine exporter, ThrE tRNA-synt_2d PF01409.20 KIY49342.1 - 6.8e-88 294.3 0.0 9.3e-88 293.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KIY49342.1 - 9e-17 61.1 1.3 3.1e-16 59.4 0.1 2.5 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KIY49342.1 - 2.9e-11 43.2 0.0 2.3e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KIY49342.1 - 0.0006 19.0 0.8 0.0074 15.4 0.0 2.5 2 1 1 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KIY49342.1 - 0.0024 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 KIY49342.1 - 0.022 14.8 0.2 0.022 14.8 0.2 1.9 2 0 0 2 2 2 0 PheRS DNA binding domain 2 RelB_N PF18506.1 KIY49342.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain Pex2_Pex12 PF04757.14 KIY49343.1 - 1.2e-34 119.9 6.5 1.6e-34 119.4 6.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 KIY49343.1 - 0.00051 20.0 1.6 0.001 19.0 0.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIY49343.1 - 0.0074 16.4 0.8 0.02 15.0 0.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIY49343.1 - 0.01 15.8 2.2 0.034 14.2 2.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KIY49343.1 - 0.013 15.8 2.6 0.061 13.7 0.7 2.4 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 KIY49343.1 - 0.02 14.8 2.3 0.045 13.6 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY49343.1 - 0.02 14.8 2.1 0.064 13.1 2.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY49343.1 - 0.021 14.7 0.4 0.021 14.7 0.4 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-4CXXC_R1 PF10497.9 KIY49343.1 - 0.031 14.5 0.4 0.065 13.5 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_3 PF13920.6 KIY49343.1 - 0.046 13.6 6.1 0.12 12.2 2.6 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_C6 PF00851.18 KIY49343.1 - 0.26 10.1 0.3 1.5 7.7 0.0 1.9 2 0 0 2 2 2 0 Helper component proteinase IBN_N PF03810.19 KIY49344.1 - 1.2e-10 41.1 0.5 1.4e-08 34.5 0.3 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KIY49344.1 - 0.054 13.6 0.0 0.28 11.2 0.0 2.4 1 0 0 1 1 1 0 Exportin 1-like protein Vps51 PF08700.11 KIY49344.1 - 0.1 12.7 1.6 1.2 9.3 0.1 3.2 3 0 0 3 3 3 0 Vps51/Vps67 FANCI_S1-cap PF14674.6 KIY49344.1 - 0.28 11.3 1.3 2 8.6 0.0 3.0 3 0 0 3 3 3 0 FANCI solenoid 1 cap Slx4 PF09494.10 KIY49345.1 - 0.0006 19.7 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease Mur_ligase_M PF08245.12 KIY49346.1 - 5.9e-07 29.7 0.0 0.0014 18.7 0.0 3.1 2 1 1 3 3 3 2 Mur ligase middle domain BRCT PF00533.26 KIY49347.1 - 6.8e-12 45.6 0.1 2.1e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KIY49347.1 - 2.9e-10 40.4 0.0 5.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KIY49347.1 - 3e-05 24.2 0.0 6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 KIY49347.1 - 0.0062 16.5 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 KIY49347.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain AA_permease PF00324.21 KIY49348.1 - 8.1e-112 374.2 42.2 9.8e-112 374.0 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY49348.1 - 6.4e-31 107.6 42.3 7.8e-31 107.3 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.12 KIY49348.1 - 0.052 13.8 0.2 2 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) MAP17 PF15807.5 KIY49348.1 - 0.53 10.5 1.2 1.1 9.5 1.2 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 OPT PF03169.15 KIY49349.1 - 2.2e-142 475.8 42.6 2.5e-142 475.6 42.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein COX7C PF02935.16 KIY49349.1 - 0.22 11.8 6.6 5.6 7.3 0.6 3.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Caveolin PF01146.17 KIY49349.1 - 9.8 6.1 10.3 14 5.7 1.4 2.8 3 0 0 3 3 3 0 Caveolin JAB PF01398.21 KIY49351.1 - 1.2e-32 112.3 0.2 2.3e-32 111.4 0.2 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KIY49351.1 - 3.1e-13 50.1 1.3 6.5e-13 49.1 1.3 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KIY49351.1 - 2.1e-07 30.7 0.0 3.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KIY49351.1 - 0.011 15.8 1.4 0.021 14.9 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) DUF5624 PF18538.1 KIY49351.1 - 0.053 13.6 0.2 0.097 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) UCH PF00443.29 KIY49352.1 - 1.9e-05 24.3 0.0 2.5e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CUE PF02845.16 KIY49352.1 - 0.00073 19.2 0.0 0.0032 17.1 0.0 2.2 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 KIY49352.1 - 0.019 14.8 0.2 0.15 11.9 0.0 2.5 3 0 0 3 3 3 0 UBA-like domain UIM PF02809.20 KIY49352.1 - 0.032 14.2 10.4 0.17 11.9 0.6 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif RPN13_C PF16550.5 KIY49353.1 - 0.014 15.5 0.6 0.042 14.0 0.6 1.7 1 0 0 1 1 1 0 UCH-binding domain Vps52 PF04129.12 KIY49354.1 - 1.3e-58 199.1 1.2 1.5e-42 146.0 0.6 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 KIY49354.1 - 3.4e-06 25.8 0.7 1.5e-05 23.6 0.9 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec3 MscS_porin PF12795.7 KIY49354.1 - 0.1 12.1 0.7 0.26 10.8 0.7 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Pkinase PF00069.25 KIY49356.1 - 6e-61 206.1 0.0 4e-41 141.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49356.1 - 1.2e-29 103.4 0.0 3.8e-23 82.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KIY49356.1 - 1.1e-11 44.9 0.0 2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KIY49356.1 - 5.7e-08 32.4 0.7 0.0015 17.9 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KIY49356.1 - 0.0013 18.8 0.0 0.0036 17.3 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY49356.1 - 0.007 15.4 0.0 0.029 13.3 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 KIY49356.1 - 0.016 14.8 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KIY49356.1 - 0.016 14.8 0.1 6.7 6.3 0.0 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY49356.1 - 0.041 13.2 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lactamase_B_2 PF12706.7 KIY49358.1 - 9.3e-09 35.1 0.1 0.0063 16.1 0.0 3.7 2 1 1 3 3 3 3 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KIY49358.1 - 3.4e-08 33.0 0.0 7.4e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 KIY49358.1 - 1.9e-06 28.0 0.0 4.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 KIY49358.1 - 0.064 12.4 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II PsaL PF02605.15 KIY49358.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI THOC7 PF05615.13 KIY49359.1 - 2.6e-28 99.0 4.6 2.9e-28 98.8 4.6 1.0 1 0 0 1 1 1 1 Tho complex subunit 7 Golgin_A5 PF09787.9 KIY49359.1 - 0.0021 17.6 1.2 0.0027 17.2 1.2 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 TolA_bind_tri PF16331.5 KIY49359.1 - 0.0085 16.1 1.6 0.016 15.2 1.6 1.5 1 1 0 1 1 1 1 TolA binding protein trimerisation CENP-Q PF13094.6 KIY49359.1 - 0.012 15.8 1.1 0.014 15.6 1.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HALZ PF02183.18 KIY49359.1 - 0.061 13.6 0.0 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Retrotran_gag_2 PF14223.6 KIY49360.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4191 PF13829.6 KIY49361.1 - 0.04 13.2 0.1 0.052 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Acetyltransf_1 PF00583.25 KIY49362.1 - 5.6e-13 49.2 0.0 6.5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY49362.1 - 1.9e-09 37.6 0.1 2.1e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY49362.1 - 4.7e-07 30.1 0.0 6.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY49362.1 - 9.6e-06 25.5 0.1 1.5e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIY49362.1 - 2.2e-05 24.6 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KIY49362.1 - 0.00044 19.8 0.3 0.00044 19.8 0.3 1.5 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 KIY49362.1 - 0.071 13.8 0.0 0.18 12.5 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.7 KIY49363.1 - 1.6e-05 25.6 7.3 6.7e-05 23.6 7.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KIY49363.1 - 0.00025 20.6 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KIY49363.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KIY49363.1 - 0.027 14.0 0.0 0.96 8.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 KIY49363.1 - 0.033 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KIY49363.1 - 0.035 13.8 0.2 0.077 12.7 0.2 1.6 1 1 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 KIY49363.1 - 0.098 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 KIY49363.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 KIY49363.1 - 0.22 10.6 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PAF-AH_p_II PF03403.13 KIY49364.1 - 9.2e-38 129.7 0.0 5.9e-33 113.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KIY49364.1 - 3.9e-05 22.7 0.0 0.0046 15.9 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KIY49364.1 - 4.7e-05 22.8 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KIY49364.1 - 0.016 14.2 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase Thioesterase PF00975.20 KIY49364.1 - 0.092 12.8 0.7 13 5.8 0.2 2.5 2 1 0 2 2 2 0 Thioesterase domain Glyco_hydro_79C PF16862.5 KIY49365.1 - 2e-09 38.2 0.1 9e-09 36.2 0.1 2.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain tRNA-synt_1c PF00749.21 KIY49366.1 - 3.6e-109 364.5 0.0 4.7e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KIY49366.1 - 1.2e-30 106.6 0.0 2.1e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KIY49366.1 - 1e-27 97.1 0.0 9.6e-27 94.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KIY49366.1 - 5.5e-08 33.6 1.5 6.8e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 ATP-synt_F PF01990.17 KIY49367.1 - 5.4e-33 113.2 0.1 6.3e-33 113.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 KIY49367.1 - 0.054 13.3 0.1 0.064 13.1 0.1 1.1 1 0 0 1 1 1 0 PIN like domain zf-MYND PF01753.18 KIY49368.1 - 3.7e-09 36.5 11.6 7.7e-09 35.5 11.6 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY49368.1 - 0.0035 17.6 8.5 0.0036 17.6 3.9 2.4 1 1 1 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding DUF2052 PF09747.9 KIY49370.1 - 4.4e-08 33.5 9.9 9.5e-08 32.4 9.9 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Myb_DNA-binding PF00249.31 KIY49371.1 - 1.3e-25 89.3 8.8 9e-12 45.0 0.1 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY49371.1 - 3e-15 56.2 9.7 1.8e-07 31.3 0.0 3.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIY49371.1 - 5.5e-06 26.7 5.5 0.00023 21.5 1.2 3.1 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain MbeD_MobD PF04899.12 KIY49371.1 - 0.019 15.0 3.4 4.1 7.6 0.2 2.8 3 0 0 3 3 3 0 MbeD/MobD like MADF_DNA_bdg PF10545.9 KIY49371.1 - 0.025 14.9 2.3 0.25 11.7 0.7 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Atg29_N PF18388.1 KIY49371.1 - 4.3 7.2 6.2 37 4.2 0.1 3.5 3 1 0 3 3 3 0 Atg29 N-terminal domain ABC2_membrane PF01061.24 KIY49372.1 - 2.9e-84 281.7 49.2 5.3e-48 163.2 19.0 3.3 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KIY49372.1 - 6.6e-39 131.7 11.6 1.7e-35 120.8 0.4 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 KIY49372.1 - 3.4e-35 121.5 0.0 1e-16 61.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KIY49372.1 - 1.4e-17 64.1 0.0 3.1e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KIY49372.1 - 2.5e-06 27.5 0.0 0.0026 17.7 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_25 PF13481.6 KIY49372.1 - 5.3e-06 26.1 0.2 2.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY49372.1 - 3.4e-05 24.0 0.1 0.0083 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIY49372.1 - 4.3e-05 23.5 0.0 0.071 12.9 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY49372.1 - 6.3e-05 23.4 0.1 0.014 15.8 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KIY49372.1 - 0.00024 21.6 0.0 0.004 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIY49372.1 - 0.00049 19.6 0.0 0.21 11.0 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KIY49372.1 - 0.00095 18.9 0.4 0.1 12.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY49372.1 - 0.001 18.7 1.1 0.051 13.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY49372.1 - 0.011 16.0 0.2 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIY49372.1 - 0.017 15.1 0.1 3 7.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KIY49372.1 - 0.018 14.6 0.9 0.11 12.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KIY49372.1 - 0.062 13.7 0.0 3 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIY49372.1 - 0.13 12.4 0.1 30 4.7 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase SCA7 PF08313.12 KIY49373.1 - 5.3e-24 83.9 0.0 5.5e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain Tachystatin_A PF11406.8 KIY49373.1 - 0.016 15.3 0.3 0.019 15.0 0.3 1.3 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A DUF533 PF04391.12 KIY49374.1 - 0.007 16.0 1.3 0.37 10.3 0.5 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF533) Trp_oprn_chp PF09534.10 KIY49374.1 - 0.079 12.8 1.7 0.13 12.1 1.7 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) GT87 PF09594.10 KIY49374.1 - 3.7 7.2 9.4 25 4.5 9.1 2.0 1 1 0 1 1 1 0 Glycosyltransferase family 87 DUF5310 PF17237.2 KIY49375.1 - 3.7e-19 68.3 4.2 3.7e-19 68.3 4.2 1.4 2 0 0 2 2 2 1 Family of unknown function (DUF5310) LRR_4 PF12799.7 KIY49376.1 - 4.2e-08 33.4 2.7 0.84 10.2 0.0 5.8 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIY49376.1 - 1.7e-07 30.8 13.0 0.035 14.2 0.0 7.4 7 1 1 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 KIY49376.1 - 0.0022 18.3 6.0 5.3 8.0 0.0 5.2 4 1 0 4 4 4 2 Leucine Rich Repeat RhoGEF PF00621.20 KIY49377.1 - 6.1e-33 114.6 0.0 1.4e-32 113.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain CENP-F_leu_zip PF10473.9 KIY49377.1 - 0.058 13.4 13.7 0.39 10.7 6.7 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SYF2 PF08231.12 KIY49377.1 - 0.64 10.4 5.7 19 5.6 4.4 2.8 1 1 1 2 2 2 0 SYF2 splicing factor PI3K_P85_iSH2 PF16454.5 KIY49377.1 - 0.7 9.5 8.7 2.2 7.9 8.7 1.8 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HIP1_clath_bdg PF16515.5 KIY49377.1 - 1.3 9.7 15.9 0.34 11.6 8.4 2.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Myb_DNA-bind_3 PF12776.7 KIY49377.1 - 2.3 9.3 4.6 7.5 7.6 0.6 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain TerB_C PF15615.6 KIY49377.1 - 3.3 8.0 10.9 1 9.6 7.3 2.1 2 0 0 2 2 2 0 TerB-C domain GAS PF13851.6 KIY49377.1 - 3.4 6.9 16.3 57 3.0 16.3 2.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 KIY49377.1 - 4.5 7.5 7.3 4.4 7.5 0.2 2.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 IFT57 PF10498.9 KIY49377.1 - 6 5.7 12.3 0.84 8.5 4.7 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 KIY49377.1 - 6.6 6.2 8.0 22 4.5 8.0 1.9 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 KIY49377.1 - 8.9 6.6 8.8 9.9 6.5 1.1 3.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KIY49377.1 - 9.3 6.3 9.1 2.2 8.3 2.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) F-box-like PF12937.7 KIY49378.1 - 2.6e-09 36.8 4.4 1.2e-08 34.7 4.4 2.3 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY49378.1 - 1.7e-08 34.6 14.0 0.26 11.7 0.0 6.9 4 3 2 6 6 6 4 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY49378.1 - 2.8 7.9 11.7 0.14 12.1 4.1 2.6 2 0 0 2 2 2 0 F-box domain SANT_DAMP1_like PF16282.5 KIY49379.1 - 1.5e-30 105.2 2.0 2.6e-30 104.4 2.0 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 APG6_N PF17675.1 KIY49379.1 - 0.0039 17.7 1.9 0.012 16.2 1.4 1.9 2 0 0 2 2 2 1 Apg6 coiled-coil region Myb_DNA-binding PF00249.31 KIY49379.1 - 0.012 15.8 0.0 0.045 13.9 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY49379.1 - 0.036 14.3 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain XRCC4 PF06632.12 KIY49379.1 - 2.6 6.8 7.1 0.21 10.4 2.3 1.5 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 GST_N PF02798.20 KIY49380.1 - 1.2e-11 44.8 0.1 2.1e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY49380.1 - 5.7e-11 42.6 0.1 9.2e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY49380.1 - 5.8e-10 39.4 0.1 1.2e-09 38.5 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY49380.1 - 0.044 13.8 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY49380.1 - 0.11 13.2 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF202 PF02656.15 KIY49381.1 - 1.7e-15 57.2 1.8 1.7e-15 57.2 1.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) zf-U1 PF06220.12 KIY49382.1 - 3.8e-19 68.2 5.8 5.1e-19 67.7 5.8 1.2 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 KIY49382.1 - 0.029 14.3 1.6 0.029 14.3 1.6 1.7 2 0 0 2 2 2 0 CLIP1 zinc knuckle zf-C2H2_jaz PF12171.8 KIY49382.1 - 6.6 7.1 8.3 1.1e+02 3.3 8.3 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding LSM PF01423.22 KIY49383.1 - 1.9e-18 65.9 0.0 2.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KIY49383.1 - 0.17 12.0 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DUF4050 PF13259.6 KIY49384.1 - 0.018 15.3 0.4 2.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) AAA PF00004.29 KIY49385.1 - 2.8e-20 73.1 0.0 4.7e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIY49385.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KIY49385.1 - 0.037 14.4 0.2 3.9 7.8 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain ATPase_2 PF01637.18 KIY49385.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KIY49385.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIY49385.1 - 0.23 10.8 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Lactamase_B_6 PF16661.5 KIY49386.1 - 4.3e-51 173.1 0.0 7.1e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KIY49386.1 - 9.8e-26 90.9 0.0 9.8e-26 90.9 0.0 3.4 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KIY49386.1 - 5.2e-19 68.6 0.0 2.8e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KIY49386.1 - 0.00039 20.3 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KIY49386.1 - 0.024 14.2 0.0 0.61 9.6 0.0 2.3 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY49386.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Atrophin-1 PF03154.15 KIY49386.1 - 0.39 9.0 2.5 0.77 8.0 2.5 1.4 1 0 0 1 1 1 0 Atrophin-1 family PAH PF02671.21 KIY49387.1 - 1e-15 57.6 0.3 1.4e-15 57.1 0.3 1.2 1 0 0 1 1 1 1 Paired amphipathic helix repeat COX5A PF02284.16 KIY49387.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Abhydrolase_3 PF07859.13 KIY49388.1 - 8.9e-26 91.0 1.8 3.6e-18 66.2 1.9 3.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY49388.1 - 3.8e-09 35.9 0.3 6.1e-07 28.6 0.3 2.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIY49388.1 - 0.091 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Tubulin PF00091.25 KIY49389.1 - 1.7e-65 220.9 0.0 2.3e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY49389.1 - 2.2e-48 163.6 0.0 3.6e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KIY49389.1 - 0.0003 20.5 0.0 0.00055 19.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KIY49390.1 - 3.6e-67 226.4 0.0 5.5e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY49390.1 - 1.2e-46 157.9 0.0 1.9e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KIY49390.1 - 0.0022 17.7 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain HAD_2 PF13419.6 KIY49391.1 - 7e-18 65.3 0.0 1.6e-17 64.1 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY49391.1 - 2.1e-10 41.3 0.0 1.6e-05 25.3 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY49391.1 - 2e-05 24.6 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KIY49391.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY49391.1 - 0.17 12.3 0.2 0.23 11.8 0.2 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sec15 PF04091.12 KIY49392.1 - 3.8e-96 322.2 0.4 6.8e-96 321.4 0.4 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 KIY49392.1 - 1.7e-07 31.4 0.6 1.2e-06 28.8 0.6 2.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 KIY49392.1 - 3e-05 23.9 0.4 0.00032 20.6 0.2 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps51 PF08700.11 KIY49392.1 - 4.5e-05 23.5 1.2 0.00035 20.6 0.1 2.9 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KIY49392.1 - 0.003 17.6 2.6 0.0071 16.4 1.0 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 KIY49392.1 - 0.0056 14.7 0.0 1.8 6.4 0.0 2.4 2 0 0 2 2 2 2 Prominin CHASE9 PF17153.4 KIY49392.1 - 0.04 14.1 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular RAC_head PF16717.5 KIY49392.1 - 0.13 13.2 1.9 2 9.4 0.0 3.7 4 1 1 5 5 5 0 Ribosome-associated complex head domain Arf PF00025.21 KIY49393.1 - 1.2e-78 262.6 0.1 1.4e-78 262.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIY49393.1 - 1.5e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIY49393.1 - 3e-14 52.8 0.0 3.7e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KIY49393.1 - 6.4e-13 48.6 1.2 3.9e-09 36.1 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KIY49393.1 - 1.1e-12 47.8 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIY49393.1 - 1.4e-10 40.9 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY49393.1 - 2.4e-06 27.6 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KIY49393.1 - 0.0071 15.7 0.7 0.02 14.2 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase DSPc PF00782.20 KIY49394.1 - 1.5e-27 96.0 0.0 1.8e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY49394.1 - 0.0023 17.5 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIY49394.1 - 0.047 14.0 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain SIP1 PF04938.12 KIY49396.1 - 1.1e-26 94.0 0.0 1.4e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) NOP19 PF10863.8 KIY49397.1 - 0.043 13.7 1.2 0.16 11.8 0.1 2.4 2 0 0 2 2 2 0 Nucleolar protein 19 G-patch_2 PF12656.7 KIY49397.1 - 0.054 13.6 0.0 0.054 13.6 0.0 2.5 3 0 0 3 3 3 0 G-patch domain FXR_C1 PF16096.5 KIY49397.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DUF1168 PF06658.12 KIY49397.1 - 6.2 6.6 14.7 11 5.9 5.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) GPI-anchored PF10342.9 KIY49398.1 - 7.2e-08 33.1 0.1 7.2e-08 33.1 0.1 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CD225 PF04505.12 KIY49398.1 - 0.037 14.2 7.1 1.2 9.3 3.5 2.5 2 1 0 2 2 2 0 Interferon-induced transmembrane protein Sporozoite_P67 PF05642.11 KIY49398.1 - 0.074 11.1 9.3 0.08 11.0 9.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BES1_N PF05687.13 KIY49398.1 - 0.21 12.0 6.4 0.29 11.5 6.4 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Macoilin PF09726.9 KIY49398.1 - 2.4 6.6 5.7 2.9 6.3 5.7 1.0 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 KIY49398.1 - 3.7 5.7 12.7 3.7 5.7 12.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 KIY49398.1 - 4.8 5.2 12.8 5.2 5.0 12.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF515 PF04415.12 KIY49398.1 - 5.7 5.2 13.6 7 4.9 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FAM199X PF15814.5 KIY49398.1 - 9.4 5.2 16.7 14 4.6 16.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X ECH_1 PF00378.20 KIY49399.1 - 1.1e-52 178.8 0.0 1.3e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY49399.1 - 4.8e-30 105.2 0.0 1.1e-28 100.7 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KIY49399.1 - 0.12 12.3 0.0 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 Peptidase_M28 PF04389.17 KIY49400.1 - 1.4e-25 90.2 0.0 1.9e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY49400.1 - 0.00036 20.3 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HTH_43 PF09904.9 KIY49400.1 - 0.024 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix TCL1_MTCP1 PF01840.17 KIY49400.1 - 0.043 13.5 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 TCL1/MTCP1 family Amidohydro_2 PF04909.14 KIY49402.1 - 4.4e-25 89.1 0.0 2.7e-24 86.5 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase QRPTase_C PF01729.19 KIY49403.1 - 4.7e-49 166.4 0.1 5.7e-49 166.1 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KIY49403.1 - 1.5e-19 69.8 0.0 7.1e-19 67.7 0.0 2.2 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Sec10 PF07393.11 KIY49405.1 - 7.1e-226 752.0 0.0 9.9e-226 751.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 I_LWEQ PF01608.17 KIY49405.1 - 0.039 14.2 0.3 8 6.7 0.0 2.7 2 0 0 2 2 2 0 I/LWEQ domain GNAT_like PF18407.1 KIY49405.1 - 1.4 9.4 3.8 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain SKN1 PF03935.15 KIY49406.1 - 1e-172 575.1 8.5 1.3e-172 574.7 8.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) RNA_pol_I_TF PF04090.12 KIY49407.1 - 1.8e-09 37.4 0.3 0.00015 21.3 0.0 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_19 PF14559.6 KIY49407.1 - 0.028 14.9 1.8 0.83 10.2 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY49407.1 - 0.19 12.6 2.2 1.1e+02 4.1 0.2 4.0 3 2 2 5 5 5 0 Tetratricopeptide repeat RIX1 PF08167.12 KIY49408.1 - 8.8e-31 107.1 8.2 1.2e-30 106.7 8.2 1.1 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Telomere_reg-2 PF10193.9 KIY49408.1 - 0.011 16.2 0.1 0.027 14.9 0.1 1.7 1 0 0 1 1 1 0 Telomere length regulation protein DUF5632 PF18646.1 KIY49408.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5632) DUF5102 PF17104.5 KIY49409.1 - 4.5e-59 200.9 0.1 5.4e-59 200.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Filament PF00038.21 KIY49409.1 - 0.015 14.9 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein Snf7 PF03357.21 KIY49410.1 - 2e-47 161.0 15.5 2.4e-47 160.8 15.5 1.0 1 0 0 1 1 1 1 Snf7 DUF1319 PF07028.11 KIY49410.1 - 0.013 15.7 3.6 0.06 13.6 0.2 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1319) DUF5082 PF16888.5 KIY49410.1 - 0.032 14.5 10.3 1.7 8.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Ca_bind_SSO6904 PF18249.1 KIY49410.1 - 0.034 14.5 0.3 0.068 13.5 0.3 1.5 1 1 0 1 1 1 0 Calcium binding protein SSO6904 Prefoldin_2 PF01920.20 KIY49410.1 - 0.073 13.0 18.9 0.83 9.6 0.1 3.3 2 1 1 3 3 3 0 Prefoldin subunit Prefoldin PF02996.17 KIY49410.1 - 0.079 12.9 10.1 5.8 6.9 0.1 3.4 3 0 0 3 3 3 0 Prefoldin subunit DUF3573 PF12097.8 KIY49410.1 - 0.16 10.8 1.1 0.2 10.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Uso1_p115_C PF04871.13 KIY49410.1 - 0.54 10.6 17.0 8.7 6.7 12.2 2.6 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BST2 PF16716.5 KIY49410.1 - 0.7 10.5 12.8 17 6.0 9.0 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DHR10 PF18595.1 KIY49410.1 - 1.9 8.6 17.6 0.66 10.0 2.6 3.3 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 KIY49410.1 - 4 7.9 12.2 5.9 7.4 0.0 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Rx_N PF18052.1 KIY49410.1 - 4.9 7.5 8.2 9.4 6.6 5.2 2.7 1 1 1 2 2 2 0 Rx N-terminal domain kleA_kleC PF17383.2 KIY49410.1 - 5.7 7.3 7.9 16 5.9 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A GPS2_interact PF15784.5 KIY49410.1 - 5.9 7.4 8.6 0.65 10.5 1.7 2.3 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Abhydrolase_1 PF00561.20 KIY49411.1 - 5.5e-40 137.6 0.0 1.2e-39 136.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KIY49411.1 - 0.0029 17.3 0.1 0.0048 16.6 0.1 1.3 1 0 0 1 1 1 1 Putative esterase AP_endonuc_2 PF01261.24 KIY49412.1 - 3.8e-26 91.9 0.0 7.3e-26 90.9 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Erv26 PF04148.13 KIY49413.1 - 1e-51 175.7 7.0 1.1e-51 175.6 7.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Snf7 PF03357.21 KIY49414.1 - 1e-12 48.0 15.4 1.3e-12 47.7 15.4 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KIY49414.1 - 0.0024 17.8 5.4 0.0035 17.3 5.4 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Yuri_gagarin PF15934.5 KIY49414.1 - 0.0031 17.4 0.8 0.0055 16.6 0.1 1.6 1 1 0 1 1 1 1 Yuri gagarin DUF2857 PF11198.8 KIY49414.1 - 0.074 12.8 0.5 0.074 12.8 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) ANAPC2 PF08672.11 KIY49414.1 - 0.31 11.6 2.7 6.7 7.3 2.7 2.5 1 1 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 CDPS PF16715.5 KIY49414.1 - 1.6 8.3 4.9 1.8 8.1 2.4 1.9 1 1 1 2 2 2 0 Cyclodipeptide synthase T2SSM PF04612.12 KIY49414.1 - 2.7 8.0 9.0 0.2 11.7 0.4 2.4 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein M DEAD PF00270.29 KIY49416.1 - 1.2e-43 149.0 0.2 2e-43 148.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY49416.1 - 4.4e-31 107.5 0.1 1.8e-30 105.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY49416.1 - 0.00021 21.3 0.0 0.00046 20.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIY49416.1 - 0.00047 20.5 0.1 0.0084 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY49416.1 - 0.0098 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KIY49416.1 - 0.067 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF1871 PF08958.10 KIY49416.1 - 0.077 13.3 0.1 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) AAA_22 PF13401.6 KIY49416.1 - 0.09 13.1 0.3 0.33 11.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KIY49416.1 - 0.091 12.1 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3449 PF11931.8 KIY49417.1 - 3e-76 255.3 1.0 1.8e-74 249.5 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KIY49417.1 - 1.8e-23 82.8 2.6 2.8e-23 82.2 1.4 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 KIY49417.1 - 4.6e-07 30.0 7.6 1.4e-06 28.5 2.0 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY49417.1 - 1.7e-06 28.2 1.2 1.7e-06 28.2 1.2 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.8 KIY49417.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.7 KIY49417.1 - 0.00033 20.9 2.0 0.016 15.6 0.2 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 KIY49417.1 - 0.0084 16.2 2.4 1 9.5 0.0 3.0 2 0 0 2 2 2 1 DBF zinc finger HNOB PF07700.15 KIY49417.1 - 0.013 15.5 0.0 0.05 13.6 0.0 2.0 2 0 0 2 2 2 0 Haem-NO-binding Jnk-SapK_ap_N PF09744.9 KIY49417.1 - 0.029 14.6 0.9 0.029 14.6 0.9 2.6 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF1178 PF06676.11 KIY49417.1 - 0.09 13.2 0.7 0.23 11.9 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Laps PF10169.9 KIY49417.1 - 0.47 11.0 3.7 0.36 11.4 0.2 2.5 3 0 0 3 3 3 0 Learning-associated protein zf-C2H2_4 PF13894.6 KIY49417.1 - 0.55 11.2 3.8 31 5.8 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Sod_Fe_N PF00081.22 KIY49417.1 - 0.9 10.1 3.6 1 9.9 0.0 2.8 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain RRM_1 PF00076.22 KIY49419.1 - 1.3e-18 66.6 2.0 1.5e-18 66.4 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY49419.1 - 2.8e-08 33.4 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY49419.1 - 0.064 13.3 0.4 0.12 12.4 0.4 1.5 1 1 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 KIY49419.1 - 0.066 13.1 0.2 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif HAS-barrel PF09378.10 KIY49419.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 HAS barrel domain MpPF26 PF07666.11 KIY49420.1 - 6 7.0 11.5 4.4 7.4 6.0 2.2 2 0 0 2 2 2 0 M penetrans paralogue family 26 RNA_pol_Rpb1_5 PF04998.17 KIY49422.1 - 6e-86 288.2 0.0 1.3e-85 287.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIY49422.1 - 7.1e-54 182.5 0.0 1.8e-53 181.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KIY49422.1 - 2.7e-36 124.9 0.0 9.6e-36 123.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KIY49422.1 - 2.4e-29 102.7 2.4 1.9e-23 83.3 0.0 3.3 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KIY49422.1 - 2.2e-22 79.0 0.0 6e-22 77.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Aldedh PF00171.22 KIY49423.1 - 4e-141 470.7 0.0 4.9e-141 470.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIY49423.1 - 0.025 13.6 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) AMPKBI PF04739.15 KIY49425.1 - 1.9e-25 88.9 4.1 5.8e-24 84.2 3.1 3.3 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KIY49425.1 - 9e-20 70.7 0.0 1.5e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase ADH_zinc_N PF00107.26 KIY49426.1 - 1.7e-20 73.3 0.1 2.7e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY49426.1 - 3.9e-14 52.5 0.7 1.4e-13 50.6 0.0 2.3 3 0 0 3 3 3 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY49426.1 - 3.1e-08 34.7 0.0 5.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KIY49427.1 - 9e-06 25.7 0.0 9.9e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY49427.1 - 0.036 13.6 0.1 0.04 13.5 0.1 1.1 1 0 0 1 1 1 0 NmrA-like family PglD_N PF17836.1 KIY49427.1 - 0.054 14.2 0.0 0.062 13.9 0.0 1.1 1 0 0 1 1 1 0 PglD N-terminal domain Aldo_ket_red PF00248.21 KIY49428.1 - 1.5e-72 244.3 0.1 1.9e-72 243.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 KIY49429.1 - 1e-05 25.3 0.0 3.4e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 F-box-like 4HBT PF03061.22 KIY49430.1 - 9.6e-11 41.9 0.0 4.5e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KIY49430.1 - 9.7e-07 28.3 0.3 0.00014 21.2 0.3 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 KIY49430.1 - 9.8e-07 29.3 0.0 1.3e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily BTB PF00651.31 KIY49431.1 - 1.3e-07 31.9 0.0 4.7e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain SOG2 PF10428.9 KIY49431.1 - 0.0099 15.1 3.4 0.013 14.8 3.4 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein DUF3342 PF11822.8 KIY49431.1 - 0.11 12.7 0.1 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) DIOX_N PF14226.6 KIY49432.1 - 3.8e-28 98.6 0.1 5.7e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY49432.1 - 9.4e-15 54.9 0.0 1.8e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RIFIN PF02009.16 KIY49433.1 - 0.00096 19.1 0.4 0.0013 18.7 0.4 1.2 1 0 0 1 1 1 1 Rifin Insulin_TMD PF17870.1 KIY49433.1 - 0.027 14.5 0.1 0.084 13.0 0.0 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Amnionless PF14828.6 KIY49433.1 - 0.071 11.9 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Amnionless SPX PF03105.19 KIY49433.1 - 0.5 10.2 9.7 0.68 9.8 9.7 1.3 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 KIY49433.1 - 2.3 6.7 10.3 3.7 6.0 10.3 1.3 1 0 0 1 1 1 0 Macoilin family TrbL PF04610.14 KIY49433.1 - 2.7 7.7 7.4 1.2 8.8 1.8 2.7 2 1 1 3 3 3 0 TrbL/VirB6 plasmid conjugal transfer protein RCC1 PF00415.18 KIY49434.1 - 1.5e-60 201.7 10.2 4.7e-11 43.1 0.2 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY49434.1 - 1.9e-43 145.4 30.3 1.6e-08 34.1 0.9 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KIY49434.1 - 0.0096 16.4 2.0 27 5.2 0.0 4.5 5 0 0 5 5 5 1 SUKH-3 immunity protein Tachylectin PF14517.6 KIY49434.1 - 0.011 15.4 0.1 0.06 12.9 0.0 2.1 2 0 0 2 2 2 0 Tachylectin Hira PF07569.11 KIY49434.1 - 0.028 14.1 0.0 7.7 6.2 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split SPASM PF13186.6 KIY49434.1 - 0.16 12.5 0.0 12 6.5 0.0 2.6 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Proteasome PF00227.26 KIY49435.1 - 7.1e-39 133.3 0.0 8.8e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Caroten_synth PF04240.12 KIY49435.1 - 0.21 11.4 0.5 0.34 10.7 0.5 1.3 1 0 0 1 1 1 0 Carotenoid biosynthesis protein Pex14_N PF04695.13 KIY49436.1 - 1.2e-07 32.5 0.1 1.2e-07 32.5 0.1 3.2 2 1 2 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_17 PF00332.18 KIY49437.1 - 2.6e-07 30.5 2.7 2.5e-05 24.1 2.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Vps5 PF09325.10 KIY49439.1 - 1.8e-13 50.6 1.9 2.8e-13 50.0 1.9 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KIY49439.1 - 1.5e-09 37.9 0.0 2.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 PX domain Baculo_F PF12259.8 KIY49439.1 - 0.022 13.3 0.3 0.031 12.8 0.3 1.1 1 0 0 1 1 1 0 Baculovirus F protein Apt1 PF10351.9 KIY49440.1 - 1 8.2 9.5 1.5 7.5 9.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KIY49440.1 - 2.5 6.5 12.0 4.5 5.7 12.0 1.3 1 0 0 1 1 1 0 Macoilin family HLH PF00010.26 KIY49441.1 - 1e-11 44.6 0.5 2.1e-11 43.6 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PTP_tm PF18861.1 KIY49442.1 - 0.071 13.1 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J GTP_cyclohydro2 PF00925.20 KIY49443.1 - 6e-60 201.5 0.0 1.1e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF5472 PF17566.2 KIY49444.1 - 0.042 13.8 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5472) TFR_dimer PF04253.15 KIY49445.1 - 6.7e-19 68.2 0.0 3.5e-18 65.9 0.0 2.2 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KIY49445.1 - 6.9e-17 61.8 0.0 8e-16 58.3 0.0 2.4 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KIY49445.1 - 3e-11 43.2 0.0 6.8e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 KIY49445.1 - 0.094 12.2 0.1 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Nicastrin Far-17a_AIG1 PF04750.14 KIY49446.1 - 6.5e-37 126.8 2.6 7.9e-37 126.5 2.6 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Brix PF04427.18 KIY49447.1 - 5.7e-39 134.2 0.0 8.3e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Far-17a_AIG1 PF04750.14 KIY49448.1 - 9.1e-16 57.8 3.7 9.6e-09 34.8 0.0 3.3 1 1 2 3 3 3 3 FAR-17a/AIG1-like protein Iso_dh PF00180.20 KIY49449.1 - 1.6e-121 405.7 0.0 2e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4411 PF14367.6 KIY49449.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) NOB1_Zn_bind PF08772.11 KIY49450.1 - 3e-30 104.2 0.4 4.9e-30 103.5 0.4 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KIY49450.1 - 2.3e-28 98.5 0.0 4.5e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease zf-C2HC5 PF06221.13 KIY49450.1 - 0.064 13.3 1.5 0.13 12.3 1.5 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 KIY49450.1 - 0.08 12.4 2.2 0.49 9.9 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KIY49450.1 - 0.13 12.0 2.8 0.46 10.2 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 KIY49450.1 - 0.21 11.5 1.9 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 Nudix N-terminal P21-Arc PF04062.14 KIY49451.1 - 2.6e-73 245.8 0.0 3e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit MRVI1 PF05781.12 KIY49452.1 - 0.33 9.6 0.9 0.58 8.8 0.9 1.3 1 0 0 1 1 1 0 MRVI1 protein Haspin_kinase PF12330.8 KIY49453.1 - 4.3e-55 187.2 0.0 6.2e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Sld5 PF05916.11 KIY49454.1 - 2.2e-23 82.8 0.9 3.2e-23 82.2 0.9 1.2 1 0 0 1 1 1 1 GINS complex protein UCH PF00443.29 KIY49456.1 - 5.7e-49 166.9 0.0 6.5e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY49456.1 - 6.5e-19 68.7 0.0 7.7e-18 65.2 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KIY49456.1 - 0.022 14.2 0.1 7.2 6.0 0.2 3.0 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-C2H2 PF00096.26 KIY49457.1 - 9.3e-11 41.6 31.3 0.00023 21.4 0.9 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY49457.1 - 2e-06 28.1 28.6 0.0063 17.3 0.8 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY49457.1 - 3.4e-06 27.2 29.9 0.00059 20.2 3.5 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-MYST PF17772.1 KIY49457.1 - 0.031 13.9 2.1 0.6 9.8 0.1 2.7 1 1 1 2 2 2 0 MYST family zinc finger domain DUF4764 PF15961.5 KIY49457.1 - 0.086 11.5 5.7 0.12 11.0 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-C2H2_6 PF13912.6 KIY49457.1 - 0.15 12.1 6.3 0.71 9.9 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIY49457.1 - 0.22 12.2 0.2 0.22 12.2 0.2 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain Sprouty PF05210.13 KIY49457.1 - 0.49 10.8 5.5 1 9.8 5.5 1.5 1 0 0 1 1 1 0 Sprouty protein (Spry) zf-C2HE PF16278.5 KIY49457.1 - 1.2 9.7 15.1 0.17 12.4 0.5 3.3 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KIY49457.1 - 3.7 7.5 9.9 0.83 9.6 0.3 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type F-box PF00646.33 KIY49458.1 - 7.7e-08 32.0 1.5 7.7e-08 32.0 1.5 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY49458.1 - 4e-05 23.4 0.7 0.00012 21.9 0.7 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY49458.1 - 0.0071 16.2 0.1 0.0071 16.2 0.1 2.0 2 0 0 2 2 2 1 F-box RPA43_OB PF17875.1 KIY49459.1 - 0.057 14.1 0.5 0.089 13.4 0.5 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I SDA1 PF05285.12 KIY49459.1 - 0.11 11.8 8.9 0.14 11.6 8.9 1.1 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 KIY49459.1 - 0.3 8.8 6.8 0.38 8.5 6.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sigma70_ner PF04546.13 KIY49459.1 - 0.53 10.1 8.9 0.86 9.5 8.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 KIY49459.1 - 1 8.6 9.7 1.3 8.3 9.7 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KIY49459.1 - 1.1 7.3 13.1 1.3 7.1 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KIY49459.1 - 3 7.1 15.5 4.5 6.5 15.5 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 KIY49459.1 - 5.5 6.7 13.5 11 5.8 11.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.14 KIY49459.1 - 6.2 6.6 8.3 9.9 5.9 8.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 KIY49459.1 - 8.8 5.4 6.5 13 4.9 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIE_alpha PF02002.17 KIY49460.1 - 6.5e-19 67.7 0.7 1.6e-18 66.5 0.7 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KIY49460.1 - 1.7e-07 31.4 1.5 4.1e-07 30.2 0.3 2.3 1 1 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KIY49460.1 - 0.047 13.2 0.7 0.1 12.1 0.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Nairovirus_M PF07948.11 KIY49460.1 - 0.058 11.6 0.3 0.084 11.1 0.3 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like HTH_Crp_2 PF13545.6 KIY49460.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Hydrophobin PF01185.18 KIY49461.1 - 3.1e-21 75.8 7.0 4e-21 75.4 7.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin FF PF01846.19 KIY49463.1 - 2.5e-29 101.2 2.6 4.9e-09 36.2 0.0 5.8 5 1 0 5 5 5 4 FF domain WW PF00397.26 KIY49463.1 - 1.1e-11 44.6 14.0 3.3e-06 27.1 2.9 2.7 2 0 0 2 2 2 2 WW domain STN1_2 PF09170.10 KIY49463.1 - 0.0097 16.1 1.5 0.027 14.7 0.1 2.2 2 1 0 3 3 3 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 GFO_IDH_MocA PF01408.22 KIY49464.1 - 1.5e-18 67.7 0.0 2.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIY49464.1 - 1.4e-05 25.0 0.0 4.7e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Carboxyl_trans PF01039.22 KIY49465.1 - 4.2e-118 395.1 0.1 2.9e-102 342.8 0.3 2.0 1 1 1 2 2 2 2 Carboxyl transferase domain MdcE PF06833.11 KIY49465.1 - 0.038 13.5 0.7 0.093 12.2 0.1 1.9 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 KIY49465.1 - 0.075 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ArfGap PF01412.18 KIY49466.1 - 2.4e-34 117.9 0.1 4.8e-34 116.9 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ApoA-II PF04711.13 KIY49466.1 - 0.081 13.1 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) HATPase_c_3 PF13589.6 KIY49467.1 - 9.8e-08 31.9 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KIY49467.1 - 7e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KIY49467.1 - 8.8e-06 26.2 0.0 1.7e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KIY49467.1 - 2.7e-05 24.0 0.0 0.00026 20.8 0.0 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain MFS_1 PF07690.16 KIY49468.1 - 3.1e-11 42.8 42.4 5.8e-08 32.0 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SBDS PF01172.18 KIY49469.1 - 6.8e-14 51.7 0.0 9e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Hydrophobin PF01185.18 KIY49470.1 - 5.6e-24 84.6 9.9 7.1e-24 84.2 9.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin RNF220 PF15926.5 KIY49471.1 - 4.3e-17 62.6 4.2 1.1e-16 61.3 1.4 2.5 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KIY49471.1 - 1.1e-08 34.8 14.6 1.1e-08 34.8 14.6 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY49471.1 - 2.3e-05 24.1 19.6 0.0002 21.1 12.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY49471.1 - 2.4e-05 24.2 19.5 7.2e-05 22.7 12.9 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY49471.1 - 0.00026 20.8 14.2 0.00026 20.8 14.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY49471.1 - 0.0003 21.0 24.8 0.0018 18.5 16.6 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY49471.1 - 0.00041 20.3 8.2 0.00041 20.3 8.2 4.1 4 1 1 5 5 4 1 RING-type zinc-finger zf-Di19 PF05605.12 KIY49471.1 - 0.002 18.4 6.1 2.5 8.4 0.5 3.7 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding HTH_15 PF12324.8 KIY49471.1 - 0.036 14.0 0.1 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Prok-RING_4 PF14447.6 KIY49471.1 - 0.28 11.1 18.7 0.23 11.3 11.3 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIY49471.1 - 4.2 7.6 20.7 1.8 8.8 12.0 3.9 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING Hydrophobin PF01185.18 KIY49473.1 - 5e-15 55.9 11.4 5.8e-15 55.7 11.4 1.0 1 0 0 1 1 1 1 Fungal hydrophobin CLIP_SPH_mas PF18398.1 KIY49473.1 - 0.096 13.1 7.4 1.2 9.7 0.6 2.3 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade AFG1_ATPase PF03969.16 KIY49474.1 - 3e-89 299.4 0.0 9.1e-86 288.0 0.0 2.4 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KIY49474.1 - 0.00033 21.1 0.0 0.27 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIY49474.1 - 0.0038 17.5 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIY49474.1 - 0.055 13.9 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KIY49474.1 - 0.086 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein UreF PF01730.16 KIY49475.1 - 9.2e-26 91.0 0.2 1.3e-25 90.5 0.2 1.2 1 0 0 1 1 1 1 UreF JAB PF01398.21 KIY49476.1 - 1.6e-23 82.9 0.1 2.4e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KIY49476.1 - 2.3e-17 63.4 0.3 3.8e-17 62.7 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Tom7 PF08038.12 KIY49477.1 - 5e-21 74.1 0.4 5.7e-21 73.9 0.4 1.0 1 0 0 1 1 1 1 TOM7 family Cnd3 PF12719.7 KIY49478.1 - 3.4e-26 92.1 0.4 1.2e-25 90.3 0.4 2.1 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KIY49478.1 - 0.00044 20.3 11.1 2.3 8.7 0.0 6.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KIY49478.1 - 0.00057 20.2 2.1 0.0086 16.4 0.7 3.3 2 1 2 4 4 4 2 HEAT repeats Peptidase_M28 PF04389.17 KIY49479.1 - 4.6e-27 95.0 0.0 6.9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY49479.1 - 7.5e-07 29.1 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KIY49479.1 - 0.00032 20.2 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Nicastrin DUF3834 PF12916.7 KIY49479.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) FH2 PF02181.23 KIY49480.1 - 1.7e-79 267.6 0.0 1.7e-79 267.6 0.0 2.5 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KIY49480.1 - 1.1e-26 93.6 1.0 8.4e-26 90.7 0.0 2.8 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KIY49480.1 - 7.5e-17 61.6 0.4 7.5e-17 61.6 0.4 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain DUF1722 PF08349.11 KIY49480.1 - 0.14 12.4 0.1 0.48 10.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF4407 PF14362.6 KIY49480.1 - 0.42 9.9 12.0 0.033 13.5 2.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 KIY49480.1 - 2.1 8.5 19.1 1.9 8.6 1.5 4.3 4 1 0 4 4 4 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 KIY49480.1 - 3 8.1 19.6 7.5 6.8 4.4 4.7 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.18 KIY49480.1 - 3.7 7.9 7.8 15 6.0 0.3 4.0 4 0 0 4 4 4 0 TSC-22/dip/bun family Phlebovirus_NSM PF07246.11 KIY49480.1 - 9 5.6 16.3 8.5 5.7 4.0 3.7 3 1 0 4 4 4 0 Phlebovirus nonstructural protein NS-M HALZ PF02183.18 KIY49480.1 - 9.6 6.5 6.3 7.3 6.9 0.4 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Vac14_Fig4_bd PF11916.8 KIY49481.1 - 5.3e-78 260.8 6.5 9.1e-78 260.0 6.5 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KIY49481.1 - 3e-38 130.3 0.0 1.1e-34 118.9 0.0 3.6 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KIY49481.1 - 4.1e-09 35.9 1.0 0.11 12.8 0.0 5.7 6 0 0 6 6 5 2 HEAT repeat Cnd1 PF12717.7 KIY49481.1 - 2.5e-06 27.6 0.2 0.17 11.9 0.0 3.9 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY49481.1 - 6.4e-05 23.3 0.1 7.5 7.0 0.0 4.5 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KIY49481.1 - 6.6e-05 23.3 0.0 59 4.3 0.0 5.7 4 1 1 5 5 5 0 HEAT-like repeat CLASP_N PF12348.8 KIY49481.1 - 0.00078 19.1 0.0 9.7 5.7 0.1 4.2 3 2 1 4 4 4 2 CLASP N terminal RasGEF_N_2 PF14663.6 KIY49481.1 - 0.0028 18.0 0.7 4 7.9 0.1 4.5 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain ParcG PF10274.9 KIY49481.1 - 0.037 14.2 0.4 4.6 7.3 0.0 3.1 3 0 0 3 3 3 0 Parkin co-regulated protein EF-hand_3 PF09069.11 KIY49481.1 - 0.074 13.5 0.0 0.36 11.3 0.0 2.2 1 0 0 1 1 1 0 EF-hand YmgB PF10798.8 KIY49481.1 - 0.18 11.7 1.9 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR Y_phosphatase3 PF13350.6 KIY49482.1 - 2.3e-63 214.2 0.0 2.7e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KIY49482.1 - 0.0055 16.3 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIY49482.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MCM PF00493.23 KIY49483.1 - 2.4e-104 347.3 0.2 3.7e-104 346.7 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY49483.1 - 1e-37 128.8 0.1 2.2e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KIY49483.1 - 3.3e-26 91.6 3.4 6.4e-26 90.7 3.4 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KIY49483.1 - 8.7e-25 87.0 0.7 2e-24 85.8 0.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIY49483.1 - 6.3e-22 78.1 0.2 1.7e-21 76.7 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIY49483.1 - 1e-07 31.5 0.0 1.1e-06 28.2 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIY49483.1 - 0.0018 18.2 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIY49483.1 - 0.0042 16.8 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KIY49483.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CAP PF00188.26 KIY49484.1 - 4.7e-19 69.5 2.7 6.4e-19 69.0 2.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Acetyltransf_10 PF13673.7 KIY49485.1 - 8.9e-16 58.0 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY49485.1 - 2.1e-08 34.4 0.0 3.2e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY49485.1 - 3.1e-08 33.9 0.0 3.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KIY49485.1 - 0.00031 21.4 0.3 0.01 16.5 0.2 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 KIY49485.1 - 0.0087 15.6 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 Autoinducer synthase FR47 PF08445.10 KIY49485.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein DUF1583 PF07622.11 KIY49485.1 - 0.048 12.4 0.2 0.06 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) MOZ_SAS PF01853.18 KIY49485.1 - 0.049 13.3 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family HMG_box PF00505.19 KIY49486.1 - 3.8e-13 49.6 19.8 7.4e-07 29.5 4.7 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY49486.1 - 1.9e-11 44.4 16.6 1.7e-06 28.5 0.6 3.1 3 1 1 4 4 4 2 HMG-box domain Amidohydro_2 PF04909.14 KIY49486.1 - 0.052 13.3 0.1 0.098 12.4 0.1 1.4 1 0 0 1 1 1 0 Amidohydrolase DUF1651 PF07864.11 KIY49486.1 - 0.098 13.0 1.6 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) GRIM-19 PF06212.12 KIY49487.1 - 5.6e-26 91.0 0.3 6.4e-26 90.9 0.3 1.0 1 0 0 1 1 1 1 GRIM-19 protein ATG16 PF08614.11 KIY49488.1 - 0.53 10.5 6.4 1.4 9.1 6.4 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 KIY49488.1 - 1.3 9.5 4.0 2.9 8.4 4.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Fer4 PF00037.27 KIY49490.1 - 2.1e-13 49.4 18.2 1.5e-07 31.0 5.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KIY49490.1 - 6e-13 49.2 8.7 9.6e-13 48.5 8.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIY49490.1 - 7.2e-12 46.1 8.2 4.4e-06 27.5 1.0 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KIY49490.1 - 7.8e-10 38.7 33.5 7.6e-06 26.0 13.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIY49490.1 - 5.2e-09 36.1 21.4 3.8e-06 26.9 11.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIY49490.1 - 5.3e-09 36.1 9.3 1.2e-08 34.9 9.3 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KIY49490.1 - 1.2e-08 35.3 4.4 0.00015 22.1 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KIY49490.1 - 6.3e-07 29.1 11.0 0.0031 17.5 1.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KIY49490.1 - 1.5e-06 28.0 17.9 0.00022 21.2 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KIY49490.1 - 2e-06 27.9 10.5 0.00014 22.0 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KIY49490.1 - 9.7e-05 22.8 12.0 0.025 15.1 2.0 2.2 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KIY49490.1 - 0.00084 19.8 11.3 0.15 12.6 0.6 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 KIY49490.1 - 0.011 16.0 5.7 0.26 11.6 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KIY49490.1 - 0.033 14.4 9.6 2.7 8.2 9.3 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KIY49490.1 - 0.058 14.3 16.3 0.19 12.7 4.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KIY49490.1 - 0.073 13.9 11.1 0.96 10.3 1.3 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KIY49490.1 - 0.69 10.1 7.1 1.6 8.9 0.8 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 KIY49490.1 - 7.3 6.7 9.7 1.2 9.1 3.2 2.2 1 1 1 2 2 2 0 Epidermal patterning factor proteins PPR_2 PF13041.6 KIY49491.1 - 7.4e-35 118.9 1.8 2e-08 34.3 0.0 10.1 9 3 3 12 12 12 6 PPR repeat family PPR_3 PF13812.6 KIY49491.1 - 3.1e-34 116.8 1.2 1.2e-11 44.5 0.1 7.0 4 2 1 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIY49491.1 - 1.8e-22 78.7 3.3 0.00074 19.2 0.0 7.8 9 0 0 9 9 9 5 PPR repeat PPR PF01535.20 KIY49491.1 - 4.6e-22 76.7 7.3 0.1 12.9 0.0 13.4 15 0 0 15 15 15 5 PPR repeat PPR_long PF17177.4 KIY49491.1 - 2.1e-09 37.1 0.1 0.0012 18.2 0.1 3.6 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KIY49491.1 - 0.00044 20.9 1.3 14 6.8 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIY49491.1 - 0.014 15.9 0.8 46 5.1 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Velvet PF11754.8 KIY49492.1 - 5.2e-71 239.5 4.9 1.9e-68 231.1 3.3 2.7 2 1 0 2 2 2 2 Velvet factor Prefoldin_2 PF01920.20 KIY49493.1 - 3.9e-21 75.0 0.6 5.1e-21 74.6 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KIY49493.1 - 0.0023 17.8 1.2 0.27 11.2 0.0 2.1 1 1 0 2 2 2 1 Prefoldin subunit LXG PF04740.12 KIY49493.1 - 0.0072 16.1 1.6 0.096 12.4 0.2 2.0 2 0 0 2 2 2 1 LXG domain of WXG superfamily Phage_Mu_Gam PF07352.12 KIY49493.1 - 0.018 15.0 0.1 0.026 14.4 0.1 1.3 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein PI3K_P85_iSH2 PF16454.5 KIY49493.1 - 0.029 14.0 1.2 1.2 8.7 0.2 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DASH_Dad3 PF08656.10 KIY49493.1 - 0.04 14.0 0.8 0.076 13.1 0.8 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad3 APG6_N PF17675.1 KIY49493.1 - 0.045 14.3 0.7 9.5 6.8 0.7 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region AAA_32 PF13654.6 KIY49493.1 - 0.053 12.3 0.6 0.075 11.8 0.6 1.3 1 1 0 1 1 1 0 AAA domain Cep57_MT_bd PF06657.13 KIY49493.1 - 0.055 13.9 1.1 5.4 7.5 0.0 2.3 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SlyX PF04102.12 KIY49493.1 - 0.055 14.1 3.0 1.8 9.2 0.9 2.6 2 1 0 2 2 2 0 SlyX GrpE PF01025.19 KIY49493.1 - 0.058 13.1 0.9 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 GrpE Tropomyosin_1 PF12718.7 KIY49493.1 - 0.067 13.3 2.1 0.32 11.1 0.4 2.0 2 0 0 2 2 2 0 Tropomyosin like OmpH PF03938.14 KIY49493.1 - 0.085 13.2 3.0 6.5 7.1 3.1 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 KIY49493.1 - 0.13 12.6 1.2 3.6 8.0 0.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.9 KIY49493.1 - 0.15 12.3 1.5 0.89 9.8 0.1 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Spc24 PF08286.11 KIY49493.1 - 0.16 12.2 2.6 0.33 11.2 0.4 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 adh_short PF00106.25 KIY49495.1 - 5.7e-39 133.6 0.1 7.6e-39 133.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY49495.1 - 2.3e-28 99.4 0.1 2.8e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY49495.1 - 7.4e-07 29.2 0.1 1.1e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 KR domain ACT_7 PF13840.6 KIY49497.1 - 7.2e-12 44.9 0.1 1.1e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 ACT domain TPR_19 PF14559.6 KIY49499.1 - 7.7e-11 42.3 2.8 2.3e-05 24.8 0.1 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY49499.1 - 5.9e-05 23.6 0.9 0.012 16.3 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY49499.1 - 0.00049 20.0 0.0 1.2 9.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY49499.1 - 0.00077 20.1 6.0 5.1 8.2 0.0 4.7 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY49499.1 - 0.0049 16.8 0.4 0.48 10.6 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY49499.1 - 0.0054 16.8 0.0 5.9 7.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY49499.1 - 0.013 15.7 1.0 45 4.4 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY49499.1 - 0.014 15.6 0.1 1.1 9.5 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KIY49499.1 - 0.02 14.6 3.2 1.8 8.2 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KIY49499.1 - 0.045 14.4 1.7 33 5.5 0.7 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 KIY49499.1 - 0.072 13.3 0.5 0.67 10.2 0.3 2.4 1 1 1 2 2 2 0 HemY protein N-terminus HrpB1_HrpK PF09613.10 KIY49499.1 - 0.075 12.7 6.0 2.7 7.7 0.3 4.0 3 1 2 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 KIY49499.1 - 0.12 11.7 0.1 0.57 9.6 0.1 1.8 1 1 1 2 2 2 0 Coatomer epsilon subunit TPR_10 PF13374.6 KIY49499.1 - 0.63 10.0 2.8 1.9 8.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1043 PF06295.12 KIY49500.1 - 0.00011 22.2 0.5 0.00014 21.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Nup88 PF10168.9 KIY49501.1 - 6.5e-27 93.7 0.5 6.9e-11 40.7 0.0 3.1 3 0 0 3 3 3 3 Nuclear pore component JAKMIP_CC3 PF16034.5 KIY49501.1 - 0.33 10.9 6.7 0.62 10.0 6.7 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain Seryl_tRNA_N PF02403.22 KIY49501.1 - 4.9 7.4 7.6 1.9 8.7 2.3 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HNH_2 PF13391.6 KIY49502.1 - 5.8e-06 26.4 0.2 1.2e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease Abhydrolase_6 PF12697.7 KIY49503.1 - 9.7e-07 29.6 4.3 1.3e-06 29.2 4.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY49503.1 - 0.0023 17.2 0.0 0.0084 15.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 ACP_syn_III_C PF08541.10 KIY49503.1 - 0.0029 17.7 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2048 PF09752.9 KIY49503.1 - 0.18 10.8 0.0 0.44 9.6 0.0 1.6 2 0 0 2 2 2 0 Abhydrolase domain containing 18 CDT1_C PF16679.5 KIY49504.1 - 2.1e-13 50.5 0.0 4.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Rho_GDI PF02115.17 KIY49507.1 - 1.3e-44 152.3 0.0 1.6e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor CopC PF04234.12 KIY49507.1 - 0.11 13.5 0.3 0.24 12.5 0.3 1.8 1 1 0 1 1 1 0 CopC domain Proteasome PF00227.26 KIY49508.1 - 1.7e-49 167.9 0.1 2.1e-49 167.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY49508.1 - 2.2e-12 46.4 0.2 3.6e-12 45.7 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CSN8_PSD8_EIF3K PF10075.9 KIY49509.1 - 8.9e-30 103.6 0.0 1.3e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KIY49509.1 - 2.1e-05 24.1 0.0 2.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Proteasome PF00227.26 KIY49510.1 - 6e-45 153.1 0.1 6.9e-45 152.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Pkinase_fungal PF17667.1 KIY49511.1 - 2.3e-21 76.1 0.0 4.8e-19 68.4 0.0 3.1 3 1 1 4 4 4 2 Fungal protein kinase MFS_1 PF07690.16 KIY49512.1 - 5.2e-35 121.0 12.3 5.2e-35 121.0 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY49512.1 - 8.8e-05 22.0 3.3 0.00023 20.6 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Ytp1 PF10355.9 KIY49513.1 - 1.6e-107 358.9 5.8 2.4e-107 358.3 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KIY49513.1 - 7e-17 61.1 1.4 7e-17 61.1 1.4 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Frag1 PF10277.9 KIY49513.1 - 0.0046 16.5 0.5 0.0046 16.5 0.5 3.0 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family DUF1129 PF06570.11 KIY49513.1 - 0.28 10.7 4.2 0.37 10.2 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) FtsX PF02687.21 KIY49513.1 - 4.3 7.9 12.1 3.6 8.1 0.0 4.4 4 1 0 4 4 4 0 FtsX-like permease family UbiA PF01040.18 KIY49514.1 - 3.1e-52 177.4 18.5 4.1e-52 177.0 18.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Ost4 PF10215.9 KIY49514.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Oligosaccaryltransferase Glyco_hydro_18 PF00704.28 KIY49515.1 - 7.8e-61 206.5 3.2 9.5e-61 206.2 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 KIY49516.1 - 1.2e-36 126.4 27.5 1.6e-36 126.0 27.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TMPIT PF07851.13 KIY49516.1 - 1.4 8.1 6.4 0.51 9.5 0.2 2.3 2 0 0 2 2 2 0 TMPIT-like protein Pkinase_fungal PF17667.1 KIY49517.1 - 9.4e-24 83.9 0.0 5.2e-18 65.0 0.0 3.4 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 KIY49517.1 - 4.5e-05 23.5 1.4 0.0015 18.5 0.1 3.0 4 0 0 4 4 4 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY49517.1 - 0.074 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Mg_trans_NIPA PF05653.14 KIY49518.1 - 8.3e-58 195.8 8.7 2.7e-54 184.3 6.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KIY49518.1 - 0.00011 22.4 3.6 0.00011 22.4 3.6 3.4 3 1 0 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 KIY49518.1 - 0.016 14.5 2.6 0.041 13.1 0.2 2.5 3 0 0 3 3 3 0 Purine nucleobase transmembrane transport Ni_hydr_CYTB PF01292.20 KIY49518.1 - 0.29 10.7 4.3 0.15 11.7 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4282 PF14110.6 KIY49518.1 - 3.9 8.3 9.8 3.6 8.4 1.5 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4282) TFIID-31kDa PF02291.15 KIY49520.1 - 3.5e-37 127.2 0.0 4.9e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KIY49520.1 - 8.2e-05 22.9 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIY49520.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KIY49520.1 - 0.00092 19.2 0.0 0.0027 17.7 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated TMEM171 PF15471.6 KIY49520.1 - 9.7 5.1 6.5 13 4.7 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 NifU_N PF01592.16 KIY49521.1 - 1.9e-53 180.0 0.1 6.2e-53 178.4 0.0 1.7 1 1 1 2 2 2 1 NifU-like N terminal domain Ribosomal_S14 PF00253.21 KIY49522.1 - 1.1e-22 79.6 0.8 1.8e-22 78.8 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.8 KIY49523.1 - 2.1e-14 53.5 0.2 1.2e-13 51.1 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KIY49523.1 - 2.4e-09 37.2 11.0 2.5e-08 33.9 6.4 3.1 2 1 0 2 2 2 1 bZIP transcription factor DUF5101 PF17031.5 KIY49523.1 - 0.0046 17.0 0.1 0.0086 16.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5101) bZIP_2 PF07716.15 KIY49523.1 - 0.022 14.8 5.2 0.022 14.8 5.2 2.6 2 1 1 3 3 3 0 Basic region leucine zipper vATP-synt_E PF01991.18 KIY49523.1 - 0.032 13.6 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF5094 PF17015.5 KIY49523.1 - 0.043 13.9 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DNA_RNApol_7kD PF03604.13 KIY49524.1 - 1.3e-17 63.1 6.2 1.8e-17 62.7 6.2 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 KIY49524.1 - 0.0016 18.4 0.9 0.002 18.1 0.9 1.1 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 KIY49524.1 - 0.004 17.2 0.6 0.0043 17.1 0.6 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MCM_OB PF17207.3 KIY49524.1 - 0.004 17.0 0.7 0.004 17.0 0.7 1.0 1 0 0 1 1 1 1 MCM OB domain TF_Zn_Ribbon PF08271.12 KIY49524.1 - 0.0051 16.3 3.4 0.044 13.3 0.2 2.1 1 1 0 2 2 2 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KIY49524.1 - 0.0063 16.6 3.1 0.014 15.5 3.1 1.6 1 1 0 1 1 1 1 Zinc ribbon domain DUF3268 PF11672.8 KIY49524.1 - 0.013 15.9 1.7 0.11 12.8 1.7 1.9 1 1 0 1 1 1 0 zinc-finger-containing domain Rubredoxin_2 PF18073.1 KIY49524.1 - 0.027 14.2 3.3 2.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_10 PF10058.9 KIY49524.1 - 0.029 14.1 2.3 0.17 11.7 0.1 2.1 1 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TFIIS_C PF01096.18 KIY49524.1 - 0.03 14.2 2.1 3 7.8 0.2 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) A2L_zn_ribbon PF08792.10 KIY49524.1 - 0.043 13.5 1.4 0.31 10.8 0.2 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain GFA PF04828.14 KIY49524.1 - 0.048 14.0 1.7 5.3 7.5 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF1451 PF07295.11 KIY49524.1 - 0.057 13.5 1.9 0.067 13.2 1.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF2318 PF10080.9 KIY49524.1 - 0.057 13.5 1.4 0.12 12.5 1.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF35_N PF12172.8 KIY49524.1 - 0.065 13.1 2.9 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_ribbon_SprT PF17283.2 KIY49524.1 - 0.074 13.0 4.4 0.16 11.9 4.4 1.6 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Zn_ribbon_recom PF13408.6 KIY49524.1 - 0.094 13.2 3.7 0.57 10.7 1.5 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 KIY49524.1 - 0.11 12.2 2.3 4.9 6.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 KIY49524.1 - 0.11 12.3 3.2 1.9 8.3 3.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.6 KIY49524.1 - 0.11 12.4 5.6 1.4 8.9 0.2 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain zinc_ribbon_13 PF09855.9 KIY49524.1 - 0.12 12.6 2.1 0.71 10.1 0.1 2.1 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF951 PF06107.11 KIY49524.1 - 0.25 11.3 3.6 0.81 9.7 3.6 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-Sec23_Sec24 PF04810.15 KIY49524.1 - 0.36 10.9 3.0 12 6.1 1.5 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger FANCM-MHF_bd PF16783.5 KIY49525.1 - 0.37 10.9 1.2 0.69 10.0 1.2 1.4 1 0 0 1 1 1 0 FANCM to MHF binding domain RRM_1 PF00076.22 KIY49526.1 - 8.2e-27 92.8 0.0 8.8e-13 47.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.6 KIY49526.1 - 5.2e-22 77.4 1.0 1e-21 76.5 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KIY49526.1 - 2e-06 27.6 0.3 2.6e-05 24.0 0.3 2.5 2 0 0 2 2 2 1 G-patch domain Acetyltransf_10 PF13673.7 KIY49526.1 - 0.05 13.5 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Toprim_2 PF13155.6 KIY49526.1 - 0.34 11.4 1.2 3.7 8.0 0.0 3.0 3 0 0 3 3 3 0 Toprim-like Glyco_hydro_cc PF11790.8 KIY49527.1 - 1.8e-59 201.2 2.7 2e-59 201.1 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PPR_3 PF13812.6 KIY49528.1 - 0.0043 17.1 0.1 2.9 8.0 0.0 2.7 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KIY49528.1 - 0.027 14.7 0.0 1.6 9.0 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family LSM PF01423.22 KIY49531.1 - 1.4e-19 69.6 0.0 1.5e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY49531.1 - 0.033 14.3 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 KIY49531.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Nop PF01798.18 KIY49532.1 - 1.1e-67 227.9 0.0 1.8e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KIY49532.1 - 1.1e-38 132.8 6.1 2e-38 132.0 6.1 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain COA2 PF17051.5 KIY49533.1 - 1.3e-06 28.4 0.0 1.4e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 MFS_1 PF07690.16 KIY49534.1 - 1.1e-34 120.0 44.6 1.1e-34 120.0 44.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY49534.1 - 4e-08 32.5 8.9 4e-08 32.5 8.9 3.2 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 KIY49534.1 - 2.2e-06 26.4 16.7 2.2e-06 26.4 16.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NPDC1 PF06809.11 KIY49535.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) MBOAT_2 PF13813.6 KIY49537.1 - 4.9e-24 84.4 0.7 1.3e-23 83.1 0.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Pkinase PF00069.25 KIY49538.1 - 1.2e-70 237.9 0.0 1.5e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49538.1 - 7.4e-29 100.8 0.1 8.7e-21 74.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY49538.1 - 2e-10 40.5 0.3 0.029 13.7 0.0 3.0 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KIY49538.1 - 0.0002 20.3 0.0 0.00034 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY49538.1 - 0.012 15.6 0.0 0.37 10.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY49538.1 - 0.053 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Inhibitor_Mig-6 PF11555.8 KIY49538.1 - 0.074 13.2 0.0 0.5 10.5 0.0 2.3 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 SNARE_assoc PF09335.11 KIY49542.1 - 4.2e-15 56.3 8.7 4.2e-15 56.3 8.7 2.0 2 1 1 3 3 3 1 SNARE associated Golgi protein CoA_binding_3 PF13727.6 KIY49542.1 - 0.45 10.5 7.4 0.74 9.8 1.1 2.9 3 0 0 3 3 3 0 CoA-binding domain DUF1949 PF09186.11 KIY49543.1 - 0.036 14.0 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) EMC3_TMCO1 PF01956.16 KIY49543.1 - 0.14 11.9 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2076 PF09849.9 KIY49543.1 - 0.18 11.8 3.6 0.2 11.7 3.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PEX11 PF05648.14 KIY49544.1 - 4e-12 46.1 1.2 4.4e-10 39.4 1.2 2.8 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Tctex-1 PF03645.13 KIY49545.1 - 6.1e-12 45.7 0.0 7.2e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M28 PF04389.17 KIY49546.1 - 6.5e-26 91.3 0.0 8.7e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY49546.1 - 7.1e-09 35.7 0.1 2.8e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L11 PF00298.19 KIY49547.1 - 1.4e-30 105.6 0.2 2e-30 105.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KIY49547.1 - 2.7e-27 94.4 0.8 3.8e-27 93.9 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain C2 PF00168.30 KIY49552.1 - 2.3e-15 56.7 0.0 7.3e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain ALS2CR11 PF15729.5 KIY49552.1 - 0.028 13.6 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 HnRNP_M PF11532.8 KIY49552.1 - 0.11 12.7 0.9 0.11 12.7 0.9 1.8 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein M Glyco_hydro_125 PF06824.11 KIY49553.1 - 1.7e-142 475.2 0.2 2.1e-142 474.9 0.2 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Aconitase PF00330.20 KIY49555.1 - 3.2e-163 544.0 0.0 3.9e-163 543.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIY49555.1 - 6.3e-40 136.5 0.0 1e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L29e PF01779.17 KIY49556.1 - 5.2e-20 71.5 8.2 8.6e-20 70.8 8.2 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Tau95 PF09734.9 KIY49557.1 - 2e-40 138.8 1.6 3.8e-40 137.9 1.0 1.8 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KIY49557.1 - 4e-29 101.4 0.0 1.9e-28 99.2 0.0 2.1 2 0 0 2 2 2 1 Tau95 Triple barrel domain COR PF16095.5 KIY49557.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain DUF4418 PF14387.6 KIY49558.1 - 0.044 14.0 0.2 0.057 13.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) Pkr1 PF08636.10 KIY49559.1 - 5.7e-15 55.2 3.3 7.7e-15 54.8 3.3 1.2 1 0 0 1 1 1 1 ER protein Pkr1 DUF1656 PF07869.12 KIY49559.1 - 3.8 7.6 11.2 0.15 12.1 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1656) Sld5 PF05916.11 KIY49560.1 - 0.00064 20.2 0.0 0.00092 19.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein AAA PF00004.29 KIY49562.1 - 1.1e-31 110.0 0.0 1.9e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY49562.1 - 1.2e-08 35.6 0.3 8.6e-08 32.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY49562.1 - 2.3e-08 34.4 0.3 8e-07 29.4 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KIY49562.1 - 1.5e-06 28.7 0.0 2.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KIY49562.1 - 4.1e-05 23.8 0.0 8.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KIY49562.1 - 8.7e-05 22.6 0.0 0.00039 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KIY49562.1 - 9.8e-05 22.2 0.0 0.0002 21.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY49562.1 - 0.00041 20.5 0.0 0.00078 19.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIY49562.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KIY49562.1 - 0.0015 18.5 0.8 0.019 15.0 0.0 2.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIY49562.1 - 0.0017 18.3 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIY49562.1 - 0.0018 18.2 0.2 0.005 16.8 0.2 1.8 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIY49562.1 - 0.002 18.1 0.1 1.6 8.6 0.1 2.2 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KIY49562.1 - 0.0021 17.9 0.1 0.0049 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIY49562.1 - 0.0022 17.8 0.0 0.0092 15.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KIY49562.1 - 0.0026 16.9 0.1 0.065 12.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 KIY49562.1 - 0.0027 17.5 0.0 0.0062 16.3 0.0 1.6 2 0 0 2 2 1 1 Cytidylate kinase AAA_28 PF13521.6 KIY49562.1 - 0.0029 17.8 0.0 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KIY49562.1 - 0.0031 16.8 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KIY49562.1 - 0.0035 17.7 0.0 0.0088 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KIY49562.1 - 0.0043 16.8 0.0 0.015 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY49562.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KIY49562.1 - 0.012 15.2 3.2 0.26 10.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain KAP_NTPase PF07693.14 KIY49562.1 - 0.014 14.7 0.0 2.6 7.2 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 KIY49562.1 - 0.017 14.6 0.0 0.053 13.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 KIY49562.1 - 0.034 14.6 0.0 0.17 12.3 0.0 2.0 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIY49562.1 - 0.036 13.4 0.0 0.087 12.2 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KIY49562.1 - 0.049 13.6 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_13 PF13166.6 KIY49562.1 - 0.06 12.0 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIY49562.1 - 0.062 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KIY49562.1 - 0.068 13.5 1.5 0.19 12.0 0.0 2.3 2 1 1 3 3 2 0 AAA domain CPT PF07931.12 KIY49562.1 - 0.078 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.11 KIY49562.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KIY49562.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 KIY49562.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KIY49562.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pkinase PF00069.25 KIY49564.1 - 1.7e-66 224.3 0.3 6.7e-66 222.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49564.1 - 1.2e-30 106.7 0.2 2.4e-30 105.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY49564.1 - 0.002 17.0 2.5 0.014 14.2 2.5 1.9 1 1 0 1 1 1 1 Fungal protein kinase Neur_chan_memb PF02932.16 KIY49564.1 - 0.061 13.4 3.1 0.089 12.8 3.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kinase-like PF14531.6 KIY49564.1 - 0.09 12.1 10.0 2.7 7.2 0.1 3.7 4 0 0 4 4 4 0 Kinase-like TMEM51 PF15345.6 KIY49564.1 - 0.15 11.8 5.9 0.23 11.3 5.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 TFIIA PF03153.13 KIY49564.1 - 0.56 10.1 21.1 0.35 10.8 19.3 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SPATA3 PF15662.5 KIY49564.1 - 1.9 9.1 6.9 3.1 8.4 6.9 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Spt20 PF12090.8 KIY49564.1 - 4 7.0 19.8 6.1 6.4 19.8 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 KIY49564.1 - 4.4 6.0 7.1 6.2 5.5 7.1 1.1 1 0 0 1 1 1 0 Presenilin EFTUD2 PF16004.5 KIY49564.1 - 7.7 7.1 11.8 20 5.8 11.8 1.7 1 1 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF4834 PF16118.5 KIY49564.1 - 7.7 7.5 6.2 18 6.4 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Mito_carr PF00153.27 KIY49565.1 - 8.7e-50 166.6 3.4 2.8e-20 72.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sedlin_N PF04628.13 KIY49567.1 - 3.4e-35 121.0 0.0 1.3e-34 119.1 0.0 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KIY49567.1 - 1.7e-07 31.2 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Cytochrom_B561 PF03188.16 KIY49568.1 - 0.0072 16.5 2.6 0.0072 16.5 2.6 2.2 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 BOP1NT PF08145.12 KIY49569.1 - 2.8e-102 342.1 5.4 4.5e-102 341.4 5.4 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KIY49569.1 - 2.1e-19 69.5 6.7 0.00055 20.7 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY49569.1 - 5.1e-05 23.5 0.2 1.3 9.4 0.1 4.8 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 KIY49569.1 - 0.011 15.2 12.6 0.015 14.7 12.6 1.2 1 0 0 1 1 1 0 SDA1 RAB3GAP2_N PF14655.6 KIY49569.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Actin PF00022.19 KIY49570.1 - 2e-112 375.8 0.0 2.3e-112 375.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIY49570.1 - 0.00029 19.8 0.0 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein APH PF01636.23 KIY49572.1 - 2.3e-12 47.3 0.0 1.3e-11 45.0 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY49572.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2423 PF10338.9 KIY49573.1 - 1.1e-15 57.5 7.1 1.1e-15 57.5 7.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.9 KIY49573.1 - 0.0047 17.5 2.6 0.0047 17.5 2.6 1.9 2 1 0 2 2 2 1 Learning-associated protein LSM PF01423.22 KIY49574.1 - 2e-21 75.4 0.0 2.2e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY49574.1 - 0.0032 17.6 0.0 0.004 17.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.23 KIY49575.1 - 1.2e-19 70.3 0.5 2e-19 69.6 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY49575.1 - 0.0025 18.2 0.3 0.0057 17.0 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PfkB PF00294.24 KIY49576.1 - 7.4e-15 55.0 0.0 9.8e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KIY49576.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Acyl-CoA_dh_1 PF00441.24 KIY49577.1 - 5.6e-30 104.5 0.7 8.8e-30 103.9 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIY49577.1 - 1.1e-12 48.7 0.0 3.4e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIY49577.1 - 2.5e-10 40.4 0.0 5.7e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIY49577.1 - 4.8e-09 36.6 0.7 9.1e-09 35.7 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RRM_1 PF00076.22 KIY49578.1 - 2.6e-16 59.2 0.0 6.5e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L19 PF01245.20 KIY49578.1 - 3.9e-12 46.1 0.0 7.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Fungal_trans PF04082.18 KIY49579.1 - 4.9e-34 117.6 0.0 1.1e-33 116.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY49579.1 - 8.4e-10 38.6 11.4 1.4e-09 37.9 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACPS PF01648.20 KIY49581.1 - 9.9e-14 51.4 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RNA_pol_Rpc34 PF05158.12 KIY49582.1 - 9.8e-73 245.4 3.1 6.8e-64 216.4 0.5 2.1 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit E3_UFM1_ligase PF09743.9 KIY49582.1 - 0.11 12.2 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 BUD22 PF09073.10 KIY49582.1 - 5.1 6.3 35.3 0.084 12.2 26.4 1.9 2 0 0 2 2 2 0 BUD22 IMD PF08397.11 KIY49583.1 - 3.4e-07 29.9 2.2 3.4e-07 29.9 2.2 1.6 2 0 0 2 2 2 1 IRSp53/MIM homology domain ARD PF03079.14 KIY49583.1 - 0.0018 18.5 1.1 0.0035 17.5 1.1 1.4 1 0 0 1 1 1 1 ARD/ARD' family Arfaptin PF06456.13 KIY49583.1 - 0.011 15.3 1.1 0.055 13.0 0.0 2.0 1 1 0 2 2 2 0 Arfaptin-like domain BAR_3 PF16746.5 KIY49583.1 - 0.022 14.5 3.9 0.037 13.7 3.9 1.3 1 0 0 1 1 1 0 BAR domain of APPL family End3 PF12761.7 KIY49583.1 - 0.056 13.6 2.5 0.1 12.8 2.5 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 OmpH PF03938.14 KIY49583.1 - 0.066 13.6 3.8 0.072 13.4 1.9 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Phage_int_SAM_2 PF12834.7 KIY49583.1 - 0.077 13.7 0.4 0.15 12.7 0.4 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal BLOC1_2 PF10046.9 KIY49583.1 - 0.36 11.1 3.4 0.42 10.9 0.8 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 tRNA-synt_2 PF00152.20 KIY49584.1 - 4.4e-85 285.5 0.0 8.6e-85 284.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY49584.1 - 7.3e-08 32.3 0.1 1.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MRP-S26 PF14943.6 KIY49585.1 - 0.028 14.3 0.2 0.053 13.4 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Pkinase PF00069.25 KIY49586.1 - 2.8e-64 217.0 0.0 3.8e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49586.1 - 1.4e-28 99.9 0.0 1.9e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIY49586.1 - 9.4e-11 42.3 5.3 9.4e-11 42.3 5.3 2.8 2 1 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KIY49586.1 - 8.2e-09 35.7 0.1 0.00022 21.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 KIY49586.1 - 4.9e-07 29.0 0.0 8.2e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY49586.1 - 1.4e-06 27.8 0.0 6e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIY49586.1 - 0.0022 17.7 0.2 0.32 10.6 0.1 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY49586.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KIY49586.1 - 0.037 13.6 0.0 0.097 12.2 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 KIY49586.1 - 0.049 13.6 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tim17 PF02466.19 KIY49587.1 - 0.084 13.3 4.7 0.28 11.6 4.0 2.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Alpha_L_fucos PF01120.17 KIY49588.1 - 5e-81 272.9 3.7 6.4e-81 272.5 3.7 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Suc_Fer-like PF06999.12 KIY49589.1 - 5.3e-50 170.0 0.0 6.6e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Arf PF00025.21 KIY49591.1 - 1.1e-62 210.5 0.0 2.4e-62 209.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIY49591.1 - 3.4e-10 40.2 0.0 4.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KIY49591.1 - 1.2e-09 37.8 0.1 9.6e-08 31.6 0.0 2.4 2 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIY49591.1 - 3.1e-09 36.5 0.0 4.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY49591.1 - 2.3e-08 33.7 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KIY49591.1 - 2.8e-07 30.3 0.0 3.6e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Ras family DUF2373 PF10180.9 KIY49592.1 - 7.6e-22 76.9 0.7 1.2e-21 76.3 0.7 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) RR_TM4-6 PF06459.12 KIY49592.1 - 0.97 9.2 5.5 1.7 8.4 5.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3527 PF12043.8 KIY49592.1 - 2.8 7.4 6.1 0.42 10.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) MadL PF03817.13 KIY49593.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Malonate transporter MadL subunit CLASP_N PF12348.8 KIY49594.1 - 3.4e-71 239.4 5.5 2.1e-65 220.5 0.5 4.1 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 KIY49594.1 - 1.2e-08 34.5 2.0 3.3 8.2 0.0 5.8 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 KIY49594.1 - 2.4e-06 27.9 1.0 0.42 11.2 0.0 4.5 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 KIY49594.1 - 0.00029 20.9 0.1 0.041 13.9 0.0 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY49594.1 - 0.016 15.6 10.8 0.32 11.4 0.0 4.9 5 0 0 5 5 5 0 HEAT repeats Rhomboid PF01694.22 KIY49595.1 - 1.9e-30 105.8 6.4 2.5e-30 105.5 6.4 1.1 1 0 0 1 1 1 1 Rhomboid family DUF5305 PF17231.2 KIY49595.1 - 0.23 10.8 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) WD40 PF00400.32 KIY49596.1 - 5.2e-21 74.6 16.8 4.4e-06 27.3 1.4 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY49596.1 - 3.1e-10 40.2 0.1 2.1e-07 31.1 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY49596.1 - 0.042 12.5 0.0 0.27 9.8 0.0 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIY49596.1 - 0.047 12.4 0.1 0.44 9.2 0.0 2.4 1 1 2 3 3 3 0 Nup133 N terminal like DUF535 PF04393.13 KIY49599.1 - 0.025 13.9 0.1 0.025 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Pkinase PF00069.25 KIY49600.1 - 1.6e-05 24.4 0.0 1.8e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIY49600.1 - 0.00062 19.2 0.1 0.00067 19.1 0.1 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KIY49600.1 - 0.019 14.6 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 KIY49600.1 - 0.15 12.0 0.1 0.18 11.7 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAP2_3 PF14378.6 KIY49601.1 - 7e-22 78.0 20.6 7e-22 78.0 20.6 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KIY49601.1 - 5.6e-08 32.6 6.0 5.6e-08 32.6 6.0 2.3 3 1 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 KIY49601.1 - 8 7.1 15.0 0.2 12.2 7.1 2.4 2 1 2 4 4 4 0 PAP2 superfamily C-terminal Sulfate_transp PF00916.20 KIY49603.1 - 1.9e-57 194.7 21.4 3.5e-57 193.9 19.4 1.9 1 1 1 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 KIY49603.1 - 6.7e-15 54.9 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KIY49603.1 - 5.9e-11 42.0 0.0 1.4e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 STAS domain Peptidase_M19 PF01244.21 KIY49603.1 - 0.03 13.5 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) PilW PF16074.5 KIY49603.1 - 0.051 13.6 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Type IV Pilus-assembly protein W PhrC_PhrF PF11131.8 KIY49603.1 - 0.15 11.7 0.5 0.57 9.8 0.5 2.0 1 0 0 1 1 1 0 Rap-phr extracellular signalling MFS_MOT1 PF16983.5 KIY49603.1 - 2.2 8.7 27.4 0.12 12.8 2.8 4.7 4 1 1 5 5 5 0 Molybdate transporter of MFS superfamily Acetyltransf_3 PF13302.7 KIY49605.1 - 6.6e-11 43.0 0.0 8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY49605.1 - 2.5e-05 24.5 0.0 3.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ATG22 PF11700.8 KIY49606.1 - 5e-151 503.6 14.0 5.6e-151 503.4 14.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KIY49606.1 - 1.1e-09 37.7 45.4 3e-06 26.4 3.3 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily TssN PF17555.2 KIY49606.1 - 0.6 9.4 4.7 0.21 11.0 0.6 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN Rad60-SLD PF11976.8 KIY49607.1 - 1e-13 50.9 0.1 1.3e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIY49607.1 - 1.4e-07 31.1 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Gemini_coat PF00844.18 KIY49607.1 - 0.026 14.0 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family EOS1 PF12326.8 KIY49608.1 - 5.2e-27 94.9 11.6 2.2e-23 83.0 11.6 2.6 1 1 0 1 1 1 1 N-glycosylation protein OCD_Mu_crystall PF02423.15 KIY49609.1 - 3.9e-29 101.6 0.0 5.2e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KIY49609.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Peptidase_M36 PF02128.15 KIY49610.1 - 5.5e-159 529.3 1.9 7.1e-159 528.9 1.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KIY49610.1 - 1.1e-14 53.9 0.4 1.9e-14 53.2 0.4 1.4 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KIY49610.1 - 0.044 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M50B PF13398.6 KIY49610.1 - 0.19 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like AhpC-TSA PF00578.21 KIY49611.1 - 2.5e-29 101.7 0.0 3.5e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY49611.1 - 2.3e-12 46.9 0.0 2.9e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KIY49611.1 - 7.4e-10 38.5 0.1 1.4e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Helicase_C_2 PF13307.6 KIY49612.1 - 9.7e-53 178.8 0.0 2.5e-52 177.5 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KIY49612.1 - 1.8e-42 145.0 0.0 3.7e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.6 KIY49612.1 - 0.00036 20.8 0.4 1.5 9.1 0.1 2.8 2 0 0 2 2 2 2 AAA domain DEAD PF00270.29 KIY49612.1 - 0.00067 19.5 0.0 0.053 13.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY49612.1 - 0.0015 18.6 0.0 0.63 10.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIY49612.1 - 0.022 14.5 0.5 0.36 10.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KIY49612.1 - 0.054 12.7 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KIY49612.1 - 0.12 11.8 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Sugar_tr PF00083.24 KIY49613.1 - 8.1e-84 282.1 22.5 9.7e-84 281.8 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY49613.1 - 4e-13 49.0 25.3 4e-13 49.0 25.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Aminotran_3 PF00202.21 KIY49614.1 - 4.2e-104 348.4 0.0 5.2e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIY49614.1 - 0.0022 17.3 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase_fungal PF17667.1 KIY49615.1 - 5.2e-12 45.3 0.0 5.6e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase p450 PF00067.22 KIY49616.1 - 1.7e-73 247.9 0.0 3.8e-73 246.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Apt1 PF10351.9 KIY49618.1 - 2.3 7.0 6.1 2.7 6.7 6.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 KIY49618.1 - 5.3 5.2 7.5 7 4.8 7.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cys_Met_Meta_PP PF01053.20 KIY49619.1 - 6.8e-146 485.7 0.0 9.1e-146 485.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIY49619.1 - 2.4e-11 43.6 0.1 4.4e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIY49619.1 - 5.1e-10 39.0 0.2 8.1e-10 38.4 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KIY49619.1 - 2e-09 36.9 0.8 3.3e-09 36.2 0.8 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 KIY49619.1 - 0.0034 16.0 0.0 0.0052 15.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KIY49619.1 - 0.0036 16.6 0.0 0.0095 15.2 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KIY49619.1 - 0.036 12.9 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein SepSecS PF05889.13 KIY49619.1 - 0.039 12.7 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF3970 PF13113.6 KIY49619.1 - 0.14 12.4 0.0 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) DUF3040 PF11239.8 KIY49620.1 - 3.7 7.9 7.3 45 4.4 8.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) SnoaL PF07366.12 KIY49621.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase YqfD PF06898.11 KIY49621.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Glyco_hydro_61 PF03443.14 KIY49623.1 - 4.2e-41 141.2 0.1 5.4e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KIY49623.1 - 0.076 13.3 0.7 0.66 10.3 0.0 2.8 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Pkinase PF00069.25 KIY49625.1 - 8.3e-24 84.4 0.1 9e-24 84.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49625.1 - 2.5e-11 43.4 0.0 2.7e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY49625.1 - 4e-06 26.4 0.0 4.2e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY49625.1 - 3.3e-05 22.8 0.0 3.5e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY49625.1 - 0.00019 21.4 0.4 0.00025 21.0 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY49625.1 - 0.094 11.6 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KIY49625.1 - 0.097 12.2 1.4 0.13 11.8 1.4 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIY49625.1 - 0.18 11.1 0.9 0.21 10.9 0.9 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acid_PPase PF12689.7 KIY49628.1 - 6.8e-59 198.5 0.0 7.7e-59 198.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Glyco_transf_15 PF01793.16 KIY49629.1 - 1.6e-120 402.3 11.5 1.9e-120 402.0 11.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 KIY49629.1 - 0.15 12.3 0.5 0.3 11.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) YqbF PF14553.6 KIY49629.1 - 1.2 9.0 3.7 3 7.8 0.2 2.6 2 0 0 2 2 2 0 YqbF, hypothetical protein domain adh_short PF00106.25 KIY49630.1 - 2.8e-26 92.2 0.3 4.3e-26 91.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY49630.1 - 7.4e-23 81.3 1.0 4.1e-22 78.9 1.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Tubulin PF00091.25 KIY49630.1 - 0.027 14.6 1.1 0.054 13.7 1.1 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain 3HCDH_N PF02737.18 KIY49630.1 - 0.086 12.7 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2378 PF09536.10 KIY49630.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) GIDA PF01134.22 KIY49630.1 - 1.6 7.7 3.5 1.9 7.5 3.5 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A 2OG-FeII_Oxy_2 PF13532.6 KIY49631.1 - 4.9e-27 95.4 0.0 6.3e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FlaE PF07559.14 KIY49631.1 - 0.017 15.7 0.0 0.027 15.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar basal body protein FlaE Nup84_Nup100 PF04121.13 KIY49632.1 - 3e-150 501.7 0.0 3.5e-150 501.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 TPR_14 PF13428.6 KIY49632.1 - 0.0037 18.0 2.8 0.07 14.0 0.4 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_2 PF13041.6 KIY49632.1 - 0.05 13.8 0.0 21 5.4 0.0 3.6 3 0 0 3 3 3 0 PPR repeat family RHH_4 PF13467.6 KIY49632.1 - 0.12 12.2 0.3 3.2 7.7 0.0 2.9 2 0 0 2 2 2 0 Ribbon-helix-helix domain Arb1 PF09692.10 KIY49635.1 - 0.00086 18.6 0.0 0.0054 16.0 0.0 2.0 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Rad60-SLD PF11976.8 KIY49637.1 - 1.2e-22 79.5 0.1 1.3e-22 79.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIY49637.1 - 9.8e-12 44.5 0.0 1e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Bromodomain PF00439.25 KIY49641.1 - 8.9e-22 77.0 0.0 1.8e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain zf-C3HC4_2 PF13923.6 KIY49642.1 - 7.6e-11 41.7 9.4 1.3e-10 41.0 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY49642.1 - 1.9e-10 40.9 10.6 3.2e-10 40.2 10.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY49642.1 - 8e-09 35.2 9.7 1.3e-08 34.5 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY49642.1 - 1.6e-08 34.3 5.5 2.5e-08 33.6 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY49642.1 - 1.4e-06 28.5 11.0 6.8e-06 26.3 11.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIY49642.1 - 4.8e-06 26.5 6.5 1.3e-05 25.1 6.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIY49642.1 - 0.00027 20.8 9.2 0.00045 20.1 9.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY49642.1 - 0.00039 20.2 7.2 0.00073 19.3 7.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KIY49642.1 - 0.0017 18.1 9.1 0.0041 16.8 9.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KIY49642.1 - 0.002 18.1 2.1 0.0042 17.1 2.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 KIY49642.1 - 0.11 12.2 5.6 0.23 11.1 5.6 1.6 1 0 0 1 1 1 0 P-11 zinc finger DUF1272 PF06906.11 KIY49642.1 - 0.13 12.4 4.4 0.24 11.5 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Siva PF05458.12 KIY49642.1 - 0.17 11.6 5.3 0.27 10.9 5.3 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-C3HC4_4 PF15227.6 KIY49642.1 - 1.5 9.0 16.2 0.06 13.5 9.7 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KIY49642.1 - 2.6 7.9 10.2 1.2 9.0 6.6 2.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Homeodomain PF00046.29 KIY49644.1 - 1.9e-14 53.3 1.3 3.5e-14 52.4 1.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIY49644.1 - 0.04 13.8 0.1 0.04 13.8 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain Pro_isomerase PF00160.21 KIY49645.1 - 7.9e-47 159.5 0.1 9.9e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DCB PF16213.5 KIY49646.1 - 1.7e-53 180.9 0.6 8.5e-53 178.6 0.6 2.3 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KIY49646.1 - 2.6e-52 176.9 3.8 4.7e-51 172.8 0.0 3.7 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KIY49646.1 - 5e-41 140.7 1.3 2.2e-25 89.0 1.0 3.4 2 2 0 2 2 2 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 KIY49646.1 - 9.6e-07 28.6 0.4 0.00021 21.1 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) HEAT PF02985.22 KIY49646.1 - 0.16 12.3 2.6 17 6.0 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Dehydrin PF00257.19 KIY49647.1 - 0.91 10.1 7.7 1.3 9.5 7.7 1.3 1 0 0 1 1 1 0 Dehydrin aGPT-Pplase1 PF18723.1 KIY49648.1 - 2.8e-80 269.8 0.0 3.8e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 KIY49648.1 - 3.6e-10 39.6 0.4 6.9e-10 38.7 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Yos9_DD PF17880.1 KIY49648.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Yos9 dimerzation domain PARP PF00644.20 KIY49649.1 - 2.9e-12 46.6 0.0 6.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KIY49649.1 - 2.3e-06 27.3 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY49649.1 - 0.0013 19.0 0.0 0.079 13.3 0.0 2.8 2 0 0 2 2 2 1 RWD domain HA2 PF04408.23 KIY49650.1 - 2.5e-23 82.4 0.0 5.5e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY49650.1 - 4e-19 68.8 0.0 9.3e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY49650.1 - 6.2e-11 42.6 0.0 2.1e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY49650.1 - 0.00013 21.7 0.0 0.00093 19.0 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY49650.1 - 0.012 15.8 0.0 0.057 13.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIY49650.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 KIY49650.1 - 0.038 14.2 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIY49650.1 - 0.057 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIY49650.1 - 0.19 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein p450 PF00067.22 KIY49651.1 - 5.5e-67 226.5 0.0 4.1e-66 223.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Arylsulfotran_2 PF14269.6 KIY49652.1 - 3.5e-41 141.5 0.2 4.8e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY49652.1 - 1.5e-13 50.4 0.2 7.8e-11 41.5 0.2 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) TatD_DNase PF01026.21 KIY49653.1 - 1.1e-45 156.1 0.0 1.3e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase MutL_C PF08676.11 KIY49654.1 - 4.9e-21 75.0 1.2 7.7e-16 58.2 0.0 3.4 4 0 0 4 4 4 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 KIY49654.1 - 2.1e-11 43.8 0.1 4.9e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIY49654.1 - 1.3e-05 25.6 0.0 3.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CbiA PF01656.23 KIY49654.1 - 0.075 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain BPL_LplA_LipB PF03099.19 KIY49655.1 - 1.4e-06 28.3 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family G-alpha PF00503.20 KIY49656.1 - 6.6e-78 262.3 0.0 8.2e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY49656.1 - 5.7e-07 29.2 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family ThrE PF06738.12 KIY49657.1 - 7.3e-47 159.8 32.6 1.3e-41 142.5 15.9 3.2 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY49657.1 - 9e-09 35.6 7.8 9e-09 35.6 7.8 2.6 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE DIM1 PF02966.16 KIY49658.1 - 5e-68 227.0 0.1 5.6e-68 226.8 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KIY49658.1 - 8.7e-05 22.5 0.1 0.00011 22.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIY49658.1 - 0.026 14.8 0.3 0.037 14.4 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF3192 PF11399.8 KIY49658.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) FGGY_C PF02782.16 KIY49659.1 - 0.022 14.5 0.0 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain GPI-anchored PF10342.9 KIY49660.1 - 0.0013 19.4 1.6 0.0024 18.6 0.3 2.0 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KIY49660.1 - 0.0017 18.1 0.1 0.0031 17.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) VSP PF03302.13 KIY49660.1 - 0.16 10.8 0.3 0.24 10.2 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 KIY49660.1 - 0.31 10.5 8.2 0.033 13.6 1.4 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain BCIP PF13862.6 KIY49662.1 - 3.1e-69 232.9 0.1 3.8e-69 232.6 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PHP PF02811.19 KIY49664.1 - 1.5e-11 44.9 0.0 1.9e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 PHP domain Pkinase PF00069.25 KIY49665.1 - 6.4e-27 94.6 0.0 7.8e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49665.1 - 4.6e-15 55.6 0.0 5.6e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY49665.1 - 6.7e-12 44.9 0.1 8.5e-12 44.5 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY49665.1 - 1.8e-05 24.8 0.1 0.00046 20.2 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family ABC1 PF03109.16 KIY49665.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 KIY49665.1 - 0.02 14.2 0.2 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY49665.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MMS1_N PF10433.9 KIY49666.1 - 3e-155 517.6 0.0 4.5e-155 517.0 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KIY49666.1 - 5.6e-90 301.9 0.0 4.2e-89 299.0 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region DUF5031 PF16434.5 KIY49666.1 - 0.056 12.6 0.0 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5031) ANAPC4_WD40 PF12894.7 KIY49666.1 - 0.067 13.5 0.0 3 8.2 0.0 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RhoGAP PF00620.27 KIY49667.1 - 7.3e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Cep57_CLD_2 PF14197.6 KIY49667.1 - 0.24 11.5 7.4 0.82 9.8 0.2 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 HMG_box_2 PF09011.10 KIY49668.1 - 0.0019 18.7 0.1 0.0019 18.7 0.1 2.5 3 0 0 3 3 3 1 HMG-box domain Spidroin_N PF16763.5 KIY49668.1 - 0.0048 16.9 0.1 0.014 15.4 0.1 1.7 2 0 0 2 2 2 1 Major ampullate spidroin 1, spider silk protein 1, N-term DUF2299 PF10061.9 KIY49668.1 - 0.2 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) PEP-utilisers_N PF05524.13 KIY49669.1 - 0.094 12.9 0.6 0.22 11.7 0.6 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Sterol-sensing PF12349.8 KIY49670.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation DUF1192 PF06698.11 KIY49670.1 - 0.039 14.0 0.1 7.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1178 PF06676.11 KIY49670.1 - 0.053 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DivIC PF04977.15 KIY49670.1 - 0.059 13.1 3.5 3.1 7.6 0.2 2.9 1 1 1 2 2 2 0 Septum formation initiator GIT_CC PF16559.5 KIY49670.1 - 0.07 13.0 5.5 1.7 8.6 0.1 2.8 3 0 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.18 KIY49670.1 - 0.17 12.2 4.5 0.34 11.2 0.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper TSC22 PF01166.18 KIY49670.1 - 0.45 10.9 3.8 1.4 9.3 1.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KIY49670.1 - 0.63 10.2 5.7 8 6.6 0.1 3.1 3 0 0 3 3 3 0 bZIP transcription factor JIP_LZII PF16471.5 KIY49670.1 - 0.94 9.7 5.2 23 5.2 1.7 2.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II bZIP_2 PF07716.15 KIY49670.1 - 1.6 8.9 7.5 5.2 7.2 0.6 2.4 2 0 0 2 2 2 0 Basic region leucine zipper LPP PF04728.13 KIY49670.1 - 1.9 8.9 4.1 11 6.4 0.4 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 KIY49670.1 - 3.3 7.7 5.1 0.91 9.5 1.8 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 KIY49670.1 - 5.4 7.5 9.4 7.4e+02 0.7 9.4 3.2 1 1 0 1 1 1 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 KIY49670.1 - 7.1 6.8 6.0 51 4.1 0.3 2.8 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 LPD38 PF18857.1 KIY49671.1 - 0.045 13.9 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Large polyvalent protein associated domain 38 KDZ PF18758.1 KIY49672.1 - 8.6e-23 81.1 0.0 1.5e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY49672.1 - 0.0021 18.2 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY49672.1 - 0.0057 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY49672.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY49673.1 - 2.6e-37 128.6 0.0 3.9e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase HHH_8 PF14716.6 KIY49673.1 - 0.027 14.9 0.9 66 4.0 0.0 3.6 3 1 0 3 3 3 0 Helix-hairpin-helix domain OmpH PF03938.14 KIY49673.1 - 0.087 13.2 1.0 0.15 12.4 1.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BTB PF00651.31 KIY49675.1 - 6.8e-06 26.3 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 KIY49676.1 - 2.9e-23 81.7 13.7 0.00041 21.1 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.6 KIY49676.1 - 0.013 15.1 0.3 0.92 9.0 0.0 2.8 1 1 1 2 2 2 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KIY49676.1 - 0.074 13.4 0.1 3.6 8.0 0.1 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PCNA_N PF00705.18 KIY49678.1 - 2.4e-50 169.5 3.5 2.4e-50 169.5 3.5 2.0 3 0 0 3 3 3 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KIY49678.1 - 1.1e-40 138.8 0.0 3.5e-40 137.1 0.0 1.8 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 KIY49678.1 - 4.4e-08 32.5 1.5 2.3e-06 26.9 1.5 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 KIY49678.1 - 2.9e-05 23.6 0.0 6.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.12 KIY49678.1 - 0.0027 16.9 0.1 0.69 9.0 0.1 2.3 2 1 0 2 2 2 2 Hus1-like protein Cpn60_TCP1 PF00118.24 KIY49679.1 - 6.5e-86 288.9 6.8 1.1e-85 288.1 6.8 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Abhydrolase_6 PF12697.7 KIY49680.1 - 2.9e-14 54.2 0.2 3.9e-14 53.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY49680.1 - 0.07 12.4 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HAMP PF00672.25 KIY49681.1 - 8.5e-48 160.5 17.7 1.4e-08 35.0 0.1 8.7 7 1 0 7 7 7 7 HAMP domain HATPase_c PF02518.26 KIY49681.1 - 1.5e-30 106.0 0.2 5.3e-30 104.2 0.1 2.1 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIY49681.1 - 1.2e-21 76.9 2.4 2e-21 76.2 0.4 2.5 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 KIY49681.1 - 2.7e-17 62.6 1.1 1.2e-16 60.5 1.1 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 KIY49681.1 - 0.00035 19.8 1.0 0.0012 18.1 0.2 2.3 1 1 1 2 2 2 2 Autophagy protein Apg17 DUF1843 PF08898.10 KIY49681.1 - 0.0079 16.7 7.2 64 4.2 0.0 6.8 7 0 0 7 7 7 0 Domain of unknown function (DUF1843) DUF4795 PF16043.5 KIY49681.1 - 0.0091 15.6 6.7 0.2 11.3 0.1 3.7 3 2 0 3 3 3 1 Domain of unknown function (DUF4795) ALS2CR8 PF15299.6 KIY49681.1 - 0.051 13.5 0.4 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF3829 PF12889.7 KIY49681.1 - 0.079 12.4 6.4 6.4 6.2 0.1 4.1 3 2 2 6 6 6 0 Protein of unknown function (DUF3829) SpoIIID PF12116.8 KIY49681.1 - 0.14 12.3 0.8 39 4.4 0.0 4.2 4 0 0 4 4 4 0 Stage III sporulation protein D DUF5635 PF18685.1 KIY49681.1 - 0.41 10.6 1.9 14 5.7 0.0 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5635) WXG100 PF06013.12 KIY49681.1 - 0.83 9.9 17.1 0.19 12.0 0.2 6.2 6 3 2 8 8 8 0 Proteins of 100 residues with WXG ATG16 PF08614.11 KIY49681.1 - 2.4 8.3 6.0 0.95 9.6 0.1 3.3 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) AcylCoA_dehyd_C PF12186.8 KIY49681.1 - 6 7.0 12.0 62 3.8 0.1 6.3 7 1 1 8 8 8 0 Acyl-CoA dehydrogenase C terminal DUF2116 PF09889.9 KIY49682.1 - 0.0032 17.4 0.4 0.0064 16.5 0.4 1.5 1 1 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) CENP-B_dimeris PF09026.10 KIY49682.1 - 0.0033 17.8 0.1 0.0055 17.1 0.1 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DNA_binding_1 PF01035.20 KIY49683.1 - 5.6e-27 93.7 0.0 6.9e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF3808 PF10300.9 KIY49684.1 - 2.7e-67 227.6 0.0 6.2e-67 226.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KIY49684.1 - 9.7e-08 31.6 3.1 0.0075 16.3 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY49684.1 - 5e-05 22.9 1.0 0.048 13.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY49684.1 - 5e-05 23.8 0.1 0.91 10.5 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY49684.1 - 0.00014 22.4 0.4 0.012 16.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY49684.1 - 0.00026 21.0 0.1 1.4 9.3 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY49684.1 - 0.01 15.8 0.2 1.5 9.1 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY49684.1 - 0.01 16.1 7.0 1.9 8.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY49684.1 - 0.03 14.9 0.6 28 5.6 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIY49684.1 - 0.036 13.7 0.1 4.1 7.2 0.1 3.5 3 0 0 3 3 3 0 TPR repeat Spo7 PF03907.13 KIY49685.1 - 1.8e-19 70.1 0.5 2.2e-19 69.8 0.5 1.1 1 0 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 KIY49685.1 - 0.036 14.4 0.2 0.062 13.7 0.2 1.4 1 1 0 1 1 1 0 Transmembrane protein 188 MFS_2 PF13347.6 KIY49686.1 - 9.3e-12 44.2 16.7 9.3e-12 44.2 16.7 3.3 1 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 KIY49686.1 - 8.1e-06 25.0 42.7 8.1e-06 25.0 42.7 3.9 2 2 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 KIY49686.1 - 0.01 14.1 3.1 0.018 13.3 3.1 1.3 1 0 0 1 1 1 0 BT1 family MFS_5 PF05631.14 KIY49686.1 - 0.031 13.2 0.0 0.031 13.2 0.0 2.4 2 1 1 3 3 3 0 Sugar-tranasporters, 12 TM DUF1688 PF07958.11 KIY49687.1 - 1.5e-172 574.1 0.0 1.7e-172 573.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) LRR_4 PF12799.7 KIY49688.1 - 5.1e-10 39.4 5.6 0.005 17.2 0.1 5.9 3 3 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIY49688.1 - 1.3e-09 37.3 8.1 1.6 9.0 0.0 7.4 8 0 0 8 8 8 4 Leucine Rich repeat LRR_8 PF13855.6 KIY49688.1 - 8.3e-05 22.3 1.7 0.84 9.4 0.0 5.5 6 2 0 6 6 6 1 Leucine rich repeat LRR_1 PF00560.33 KIY49688.1 - 8.6e-05 22.6 0.5 84 4.3 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat Prenyltransf PF01255.19 KIY49689.1 - 1.5e-72 243.7 0.0 1.9e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Ribosomal_S17e PF00833.18 KIY49690.1 - 1.3e-58 196.2 0.0 1.7e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 IpaB_EvcA PF03278.13 KIY49690.1 - 0.2 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 IpaB/EvcA family Ribosomal_S8 PF00410.19 KIY49691.1 - 6.8e-25 87.5 0.1 1.1e-24 86.8 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 CTP_transf_1 PF01148.20 KIY49692.1 - 0.004 17.0 5.2 0.0068 16.2 5.2 1.4 1 1 0 1 1 1 1 Cytidylyltransferase family PIP5K PF01504.18 KIY49694.1 - 4.2e-47 160.7 0.1 2.1e-38 132.1 0.1 2.2 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase PNP_UDP_1 PF01048.20 KIY49695.1 - 1.8e-38 132.1 0.1 2.4e-38 131.7 0.1 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily CsbD PF05532.12 KIY49697.1 - 0.039 13.9 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 CsbD-like Pkinase PF00069.25 KIY49698.1 - 2.8e-75 253.1 0.0 3.5e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49698.1 - 1e-33 116.8 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY49698.1 - 2.6e-07 30.3 0.0 3.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY49698.1 - 9.2e-06 24.7 0.0 1.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY49698.1 - 0.0017 17.8 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY49698.1 - 0.0062 16.5 0.1 0.06 13.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Plus-3 PF03126.18 KIY49701.1 - 7e-23 81.2 0.0 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Plus-3 domain DUF775 PF05603.12 KIY49702.1 - 1.2e-48 165.3 0.0 6e-48 163.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Sof1 PF04158.14 KIY49703.1 - 2e-29 101.7 8.7 4e-29 100.7 6.6 2.3 2 0 0 2 2 2 1 Sof1-like domain WD40 PF00400.32 KIY49703.1 - 9.9e-26 89.5 10.1 7.5e-08 32.9 0.3 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY49703.1 - 3.1e-07 30.6 0.1 1.6 9.1 0.0 4.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY49703.1 - 0.0049 16.8 0.0 0.16 11.8 0.0 2.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ADH_zinc_N PF00107.26 KIY49705.1 - 1.8e-27 95.8 0.8 2.4e-26 92.2 1.5 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY49705.1 - 3.3e-16 60.6 0.0 5.9e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY49705.1 - 3.2e-12 46.3 0.1 1.4e-11 44.2 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KIY49705.1 - 0.00081 19.6 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain DUF2013 PF09431.10 KIY49707.1 - 4.8e-48 162.8 2.6 5e-48 162.8 1.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2013) Fungal_trans PF04082.18 KIY49708.1 - 1.5e-31 109.4 0.0 4.7e-31 107.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FA_hydroxylase PF04116.13 KIY49709.1 - 4.6e-24 85.2 20.7 4.6e-24 85.2 20.7 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily TFA2_Winged_2 PF18121.1 KIY49712.1 - 5.7e-22 77.2 0.0 1.4e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KIY49712.1 - 3.1e-17 62.6 0.8 3.4e-16 59.3 0.6 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF853 PF05872.12 KIY49712.1 - 0.0065 15.1 0.0 0.0086 14.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) Vps26 PF03643.15 KIY49713.1 - 9.5e-129 428.2 1.8 1.1e-128 428.0 1.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KIY49713.1 - 0.016 15.3 0.9 3.7 7.6 0.1 3.1 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Pectinesterase PF01095.19 KIY49714.1 - 1.2e-35 122.7 6.7 1.7e-35 122.2 6.7 1.1 1 0 0 1 1 1 1 Pectinesterase Thaumatin PF00314.17 KIY49716.1 - 1.9e-62 210.7 11.7 2.3e-62 210.4 11.7 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIY49716.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-1,3-glucanase Sod_Fe_C PF02777.18 KIY49717.1 - 3.3e-35 120.3 1.4 5.1e-35 119.7 1.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIY49717.1 - 4.5e-31 107.1 3.4 5.4e-31 106.9 1.8 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cytochrome_P460 PF16694.5 KIY49717.1 - 0.07 13.5 0.1 0.1 13.0 0.1 1.4 1 1 0 1 1 1 0 Cytochrome P460 Velvet PF11754.8 KIY49718.1 - 1.3e-37 130.1 0.0 5.6e-28 98.6 0.0 2.0 1 1 1 2 2 2 2 Velvet factor Glucan_synthase PF02364.15 KIY49719.1 - 0 1293.4 0.0 0 1292.9 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KIY49719.1 - 4e-42 143.6 0.1 1.1e-41 142.1 0.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NUDE_C PF04880.13 KIY49720.1 - 6.2 7.3 11.2 0.55 10.7 2.1 2.9 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region Yip1 PF04893.17 KIY49721.1 - 0.0087 15.8 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 1 Yip1 domain TMEM154 PF15102.6 KIY49721.1 - 0.025 14.5 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 KIY49721.1 - 0.027 14.8 0.8 1 9.7 0.1 2.2 2 0 0 2 2 2 0 Orf78 (ac78) RIFIN PF02009.16 KIY49721.1 - 0.035 14.0 0.2 0.035 14.0 0.2 1.6 2 0 0 2 2 2 0 Rifin PRIMA1 PF16101.5 KIY49721.1 - 0.054 13.5 0.1 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 COX2_TM PF02790.15 KIY49721.1 - 0.058 13.5 2.2 0.062 13.4 0.4 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Adeno_E3_CR2 PF02439.15 KIY49721.1 - 0.089 12.6 5.7 0.27 11.0 0.3 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Baculo_11_kDa PF06143.11 KIY49721.1 - 0.097 12.3 1.9 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family LRRC37AB_C PF14914.6 KIY49721.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.5 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF3377 PF11857.8 KIY49721.1 - 0.14 12.1 2.1 1.5 8.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Comm PF15957.5 KIY49721.1 - 0.65 10.4 3.5 9.5 6.6 0.5 2.4 2 0 0 2 2 2 0 Commissureless EphA2_TM PF14575.6 KIY49721.1 - 7.5 7.5 6.9 1.3 10.0 0.9 2.3 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HMGL-like PF00682.19 KIY49722.1 - 3.9e-48 164.3 0.0 4.9e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Glyco_hydro_28 PF00295.17 KIY49723.1 - 2.1e-33 115.8 1.4 3.2e-33 115.2 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NAD_binding_6 PF08030.12 KIY49724.1 - 3.2e-36 124.8 0.0 5e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIY49724.1 - 3e-25 88.4 0.0 5.9e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KIY49724.1 - 8.6e-14 51.7 6.4 8.6e-14 51.7 6.4 2.7 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KIY49724.1 - 0.038 14.3 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain E2_bind PF08825.10 KIY49724.1 - 0.2 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 E2 binding domain Fzo_mitofusin PF04799.13 KIY49725.1 - 0.64 9.6 3.5 1.2 8.7 3.5 1.3 1 0 0 1 1 1 0 fzo-like conserved region DAO PF01266.24 KIY49727.1 - 3.5e-60 204.4 4.2 4.2e-60 204.2 4.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY49727.1 - 1.6e-06 27.6 0.2 0.024 13.9 0.2 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY49727.1 - 8.1e-05 22.8 0.2 0.00023 21.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY49727.1 - 0.0002 20.6 5.2 0.0034 16.5 5.2 2.2 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KIY49727.1 - 0.00041 19.3 0.1 0.022 13.6 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GMC_oxred_N PF00732.19 KIY49727.1 - 0.0019 17.6 0.1 0.32 10.3 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_9 PF13454.6 KIY49727.1 - 0.0032 17.5 0.8 0.16 11.9 0.2 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIY49727.1 - 0.0056 17.2 0.1 0.018 15.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY49727.1 - 0.036 13.2 0.1 2.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 KIY49727.1 - 0.037 14.3 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 KIY49727.1 - 0.094 11.7 0.2 6.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KIY49727.1 - 0.16 11.2 1.2 2.1 7.5 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain Thi4 PF01946.17 KIY49727.1 - 0.18 11.1 1.6 0.31 10.2 0.4 1.9 2 0 0 2 2 2 0 Thi4 family BAH PF01426.18 KIY49728.1 - 0.027 14.3 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 BAH domain TB2_DP1_HVA22 PF03134.19 KIY49729.1 - 6.4e-27 93.3 4.8 1.1e-26 92.6 4.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DNA_pol_delta_4 PF04081.13 KIY49730.1 - 9e-30 103.7 0.1 1.6e-29 102.9 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Fungal_trans PF04082.18 KIY49731.1 - 7.3e-13 48.1 0.0 1.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY49731.1 - 0.17 12.1 11.1 0.46 10.6 11.1 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CLN3 PF02487.17 KIY49732.1 - 9.3e-125 416.8 4.2 1.3e-124 416.3 4.2 1.2 1 0 0 1 1 1 1 CLN3 protein DUF3488 PF11992.8 KIY49732.1 - 0.012 14.6 0.4 0.012 14.6 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) SAP PF02037.27 KIY49733.1 - 3e-05 23.7 0.1 9e-05 22.1 0.1 1.8 1 0 0 1 1 1 1 SAP domain DEAD PF00270.29 KIY49734.1 - 1.3e-46 158.6 0.0 2.4e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY49734.1 - 5.6e-23 81.4 0.0 1.6e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIY49734.1 - 8.1e-15 54.8 0.1 2.3e-14 53.4 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIY49734.1 - 0.00011 22.2 0.6 0.00033 20.7 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit NAPRTase_N PF17767.1 KIY49734.1 - 0.0038 17.6 0.2 0.035 14.5 0.0 2.2 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Cwf_Cwc_15 PF04889.12 KIY49734.1 - 2.2 8.0 27.7 0.17 11.6 15.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein VIT1 PF01988.19 KIY49736.1 - 4.5e-64 216.3 3.5 5.3e-64 216.0 3.5 1.1 1 0 0 1 1 1 1 VIT family MttA_Hcf106 PF02416.16 KIY49736.1 - 0.2 11.0 1.9 0.41 10.0 1.9 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family Pkinase PF00069.25 KIY49737.1 - 8.4e-25 87.6 0.0 4.1e-24 85.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49737.1 - 5.6e-13 48.8 0.0 9.2e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY49737.1 - 0.00029 20.8 0.1 0.0028 17.6 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY49737.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SYF2 PF08231.12 KIY49738.1 - 2.5e-54 184.0 13.4 4.1e-54 183.3 13.4 1.3 1 0 0 1 1 1 1 SYF2 splicing factor 5_nucleotid PF05761.14 KIY49738.1 - 6.3 5.6 10.4 56 2.5 10.4 1.9 1 1 0 1 1 1 0 5' nucleotidase family Pkinase PF00069.25 KIY49740.1 - 1.4e-30 106.6 0.0 1.5e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49740.1 - 1.5e-21 76.9 0.0 1.8e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY49740.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pyr_redox_2 PF07992.14 KIY49741.1 - 2.1e-42 145.4 0.0 2.5e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY49741.1 - 1.1e-09 38.7 0.0 2.7e-07 31.1 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY49741.1 - 0.018 14.3 0.1 7 5.8 0.0 2.8 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GPI-anchored PF10342.9 KIY49742.1 - 8.4e-10 39.3 1.3 8.4e-10 39.3 1.3 2.5 1 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4366 PF14283.6 KIY49742.1 - 0.02 14.9 0.7 0.031 14.3 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RIFIN PF02009.16 KIY49742.1 - 0.33 10.8 1.4 0.32 10.9 1.4 1.2 1 0 0 1 1 1 0 Rifin FSA_C PF10479.9 KIY49742.1 - 6.9 4.7 14.6 9.2 4.3 14.6 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus WH1 PF00568.23 KIY49743.1 - 4.5e-07 29.8 0.0 9.2e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 WH1 domain PBD PF00786.28 KIY49743.1 - 0.0042 17.4 0.0 0.007 16.7 0.0 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain MoCF_biosynth PF00994.24 KIY49744.1 - 4.8e-35 120.3 0.0 2.5e-34 118.0 0.0 2.1 3 0 0 3 3 3 1 Probable molybdopterin binding domain DUF2183 PF09949.9 KIY49745.1 - 1e-17 64.3 0.1 1.5e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) MCM PF00493.23 KIY49746.1 - 1.6e-97 325.0 0.0 2.5e-97 324.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY49746.1 - 2.7e-38 130.7 0.9 4.7e-38 129.9 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY49746.1 - 2.8e-26 91.8 0.7 2.8e-26 91.8 0.7 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KIY49746.1 - 1.3e-18 67.4 0.5 3.5e-18 66.1 0.2 1.9 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KIY49746.1 - 1.7e-08 34.6 0.0 4.9e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIY49746.1 - 7.6e-08 32.0 0.0 7.8e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIY49746.1 - 7.5e-05 22.6 0.0 0.0015 18.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIY49746.1 - 0.0022 17.7 0.0 1 9.1 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 KIY49746.1 - 0.0046 17.4 0.1 0.029 14.7 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIY49746.1 - 0.032 14.7 0.1 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ORC_WH_C PF18137.1 KIY49747.1 - 1e-41 142.3 0.7 1.7e-41 141.6 0.7 1.4 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KIY49747.1 - 2.4e-29 102.5 0.1 6.6e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus UPF0061 PF02696.14 KIY49748.1 - 1.5e-99 333.9 0.0 2.6e-99 333.1 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Pterin_bind PF00809.22 KIY49749.1 - 1.4e-57 195.2 0.0 2.6e-57 194.3 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KIY49749.1 - 4.6e-34 117.3 0.0 7.3e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 KIY49749.1 - 9.3e-16 58.4 0.0 1.9e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Dihydroneopterin aldolase GTP1_OBG PF01018.22 KIY49750.1 - 2.6e-41 140.8 1.1 3.1e-30 104.8 0.2 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KIY49750.1 - 1.7e-18 66.8 0.0 3.1e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIY49750.1 - 0.00038 20.0 0.1 0.45 10.0 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.18 KIY49750.1 - 0.00056 19.5 0.0 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 KIY49750.1 - 0.0015 18.2 0.2 1.7 8.2 0.1 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KIY49750.1 - 0.0048 17.0 0.0 0.018 15.1 0.0 2.0 2 1 0 2 2 2 1 Dynamin family MeaB PF03308.16 KIY49750.1 - 0.014 14.4 0.9 0.43 9.5 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KIY49750.1 - 0.026 14.0 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KIY49750.1 - 0.062 13.8 0.3 0.23 12.0 0.1 2.0 2 0 0 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 KIY49750.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Gtr1_RagA PF04670.12 KIY49750.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region p450 PF00067.22 KIY49751.1 - 3.6e-63 213.9 0.0 6e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PsbK PF02533.15 KIY49751.1 - 0.051 13.7 1.0 0.12 12.6 1.0 1.7 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component Peptidase_S24 PF00717.23 KIY49752.1 - 6.5e-07 29.2 0.0 9.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DDE_Tnp_4 PF13359.6 KIY49753.1 - 7.6e-22 77.7 0.0 1.1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIY49753.1 - 0.02 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Cyclin_N PF00134.23 KIY49755.1 - 9.5e-10 38.3 0.0 1.5e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY49755.1 - 7.1e-07 29.7 0.1 1.3e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin RTA1 PF04479.13 KIY49756.1 - 3e-56 190.3 4.5 3.7e-56 190.0 4.5 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF2189 PF09955.9 KIY49756.1 - 0.046 14.0 1.7 0.11 12.7 1.7 1.7 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) FlxA PF14282.6 KIY49757.1 - 0.0014 18.6 0.1 0.0018 18.2 0.1 1.1 1 0 0 1 1 1 1 FlxA-like protein DASH_Hsk3 PF08227.11 KIY49757.1 - 0.25 11.7 2.8 1.3 9.5 0.2 2.7 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like Matrilin_ccoil PF10393.9 KIY49757.1 - 0.33 10.8 2.1 1.2 9.1 0.3 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin MerR-DNA-bind PF09278.11 KIY49757.1 - 0.73 10.4 4.8 1.4 9.5 1.2 2.2 1 1 1 2 2 2 0 MerR, DNA binding RTA1 PF04479.13 KIY49758.1 - 1.6e-48 165.1 8.2 1.6e-48 165.1 8.2 2.0 1 1 1 2 2 2 2 RTA1 like protein DUF4605 PF15378.6 KIY49758.1 - 0.025 14.4 1.3 0.025 14.4 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) Zn_clus PF00172.18 KIY49759.1 - 2.5e-06 27.5 8.4 4.7e-06 26.6 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 KIY49759.1 - 0.0098 15.1 2.1 0.019 14.1 2.1 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Striatin PF08232.12 KIY49759.1 - 0.013 16.1 1.6 0.014 16.0 0.1 1.8 2 0 0 2 2 2 0 Striatin family BMFP PF04380.13 KIY49759.1 - 1.8 9.1 6.5 0.46 11.0 1.0 2.3 2 0 0 2 2 2 0 Membrane fusogenic activity Hemopexin PF00045.19 KIY49760.1 - 4.5e-13 48.9 3.8 0.00013 21.8 0.0 4.6 5 0 0 5 5 5 4 Hemopexin DDA1 PF10172.9 KIY49760.1 - 0.15 12.4 0.1 7.2 7.0 0.0 2.8 3 0 0 3 3 3 0 Det1 complexing ubiquitin ligase TPR_19 PF14559.6 KIY49762.1 - 1.8e-10 41.1 1.3 0.0034 17.9 0.3 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY49762.1 - 2.3e-09 37.3 1.2 0.046 14.5 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY49762.1 - 2.4e-08 33.5 0.0 0.0022 18.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY49762.1 - 4.5e-07 29.6 0.5 0.001 19.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY49762.1 - 9.9e-07 28.8 0.2 0.0047 17.1 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY49762.1 - 1.3e-06 28.9 0.3 1.6 9.4 0.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KIY49762.1 - 3.4e-06 27.3 0.1 0.1 13.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY49762.1 - 4.4e-06 26.3 0.1 0.0031 17.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY49762.1 - 0.00084 19.2 2.0 0.057 13.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIY49762.1 - 0.0037 17.6 3.7 1.8 9.2 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY49762.1 - 0.006 16.2 0.8 3.2 7.5 0.1 2.6 2 0 0 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.6 KIY49762.1 - 0.068 13.2 0.0 19 5.4 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DHHA2 PF02833.14 KIY49763.1 - 3.8e-29 101.7 0.3 1.4e-28 99.9 0.1 1.9 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 KIY49763.1 - 2.8e-11 43.5 0.5 1.1e-10 41.6 0.6 1.9 2 0 0 2 2 2 1 DHH family RTP PF02334.16 KIY49763.1 - 0.025 15.2 0.2 0.33 11.6 0.1 2.2 2 0 0 2 2 2 0 Replication terminator protein Phage-MuB_C PF09077.11 KIY49764.1 - 0.04 13.8 0.1 0.58 10.1 0.1 2.4 2 0 0 2 2 2 0 Mu B transposition protein, C terminal PCDO_beta_N PF12391.8 KIY49764.1 - 0.063 12.9 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Complex1_LYR PF05347.15 KIY49766.1 - 8.4e-13 48.2 0.5 1.1e-12 47.7 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) GvpO PF05800.11 KIY49766.1 - 0.0019 18.2 0.5 0.38 10.8 0.0 2.1 1 1 1 2 2 2 2 Gas vesicle synthesis protein GvpO HIG_1_N PF04588.13 KIY49767.1 - 2e-12 47.1 0.5 2.4e-12 46.9 0.5 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Urm1 PF09138.11 KIY49768.1 - 3e-36 123.6 0.1 3.5e-36 123.5 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KIY49768.1 - 0.0017 18.9 0.1 0.0025 18.4 0.1 1.3 1 1 0 1 1 1 1 ThiS family G-alpha PF00503.20 KIY49771.1 - 1.2e-103 347.0 0.0 1.4e-103 346.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY49771.1 - 2.7e-11 43.2 0.1 1.6e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIY49771.1 - 0.00022 21.4 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase bZIP_2 PF07716.15 KIY49772.1 - 6.9e-06 26.0 8.3 6.9e-06 26.0 8.3 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY49772.1 - 0.00016 21.7 7.7 0.00027 21.0 7.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor CDC37_N PF03234.14 KIY49772.1 - 0.0024 18.8 0.8 0.0041 18.0 0.8 1.4 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding bZIP_Maf PF03131.17 KIY49772.1 - 0.047 14.2 4.2 0.047 14.2 4.2 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor Tau95 PF09734.9 KIY49772.1 - 2.3 9.0 5.7 4 8.2 5.7 1.5 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain bZIP_1 PF00170.21 KIY49773.1 - 0.013 15.5 0.9 0.047 13.8 0.9 2.0 1 0 0 1 1 1 0 bZIP transcription factor CaKB PF03185.15 KIY49773.1 - 0.056 13.1 0.7 0.094 12.4 0.7 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Tropomyosin_1 PF12718.7 KIY49773.1 - 0.37 11.0 8.1 0.66 10.1 8.1 1.4 1 1 0 1 1 1 0 Tropomyosin like SlyX PF04102.12 KIY49773.1 - 0.94 10.1 6.0 0.88 10.2 1.9 3.0 1 1 2 3 3 3 0 SlyX Spc7 PF08317.11 KIY49773.1 - 2.3 7.0 8.1 3.6 6.4 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 KIY49773.1 - 3.9 7.3 5.1 2.3 8.1 2.5 2.0 2 0 0 2 2 2 0 Septum formation initiator Pyridoxal_deC PF00282.19 KIY49774.1 - 1.6e-62 211.4 0.0 2.1e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain adh_short PF00106.25 KIY49775.1 - 3.7e-44 150.5 1.0 4.5e-44 150.2 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY49775.1 - 1.2e-31 110.1 1.8 1.6e-31 109.6 1.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KIY49775.1 - 1e-06 28.4 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KIY49775.1 - 0.00028 20.9 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 KR domain PTH2 PF01981.16 KIY49775.1 - 0.093 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Fungal_trans PF04082.18 KIY49776.1 - 3e-08 33.0 0.2 5.8e-08 32.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain STAG PF08514.11 KIY49777.1 - 4.9e-28 97.3 0.5 1.8e-27 95.5 0.0 2.1 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.6 KIY49777.1 - 8.4e-07 29.3 0.2 7.4e-05 23.1 0.0 3.6 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 KIY49777.1 - 0.0004 20.4 0.0 1.3 9.5 0.0 4.3 3 0 0 3 3 3 2 HEAT repeat GTP-bdg_M PF16360.5 KIY49777.1 - 0.039 14.5 0.6 0.1 13.2 0.6 1.6 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region WD40 PF00400.32 KIY49778.1 - 7.3e-38 127.9 15.4 4.1e-07 30.6 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KIY49778.1 - 6.3e-07 29.2 0.4 1.8e-06 27.7 0.4 1.8 1 1 0 1 1 1 1 F-box-like Nup160 PF11715.8 KIY49778.1 - 0.00018 20.3 1.3 3.4 6.2 0.0 4.4 3 2 1 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY49778.1 - 0.00063 19.2 0.0 0.0098 15.3 0.0 2.2 2 1 0 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 KIY49778.1 - 0.0067 16.4 0.1 6 7.0 0.0 3.8 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KIY49778.1 - 0.068 11.9 0.7 11 4.6 0.1 3.0 3 1 0 3 3 3 0 Nup133 N terminal like Ribonuc_2-5A PF06479.12 KIY49779.1 - 4.5e-45 152.9 0.0 8.4e-45 152.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KIY49779.1 - 1.3e-37 129.6 0.0 9.8e-31 107.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49779.1 - 7.8e-19 68.0 0.0 1.5e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY49779.1 - 2.1e-05 23.5 0.0 8.2e-05 21.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 KIY49779.1 - 0.00078 19.3 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.6 KIY49779.1 - 0.0016 18.1 0.0 0.011 15.3 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain Kdo PF06293.14 KIY49779.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAGE_N PF12440.8 KIY49779.1 - 0.23 12.2 3.3 4.2 8.1 1.7 2.6 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Ion_trans_2 PF07885.16 KIY49780.1 - 3.8e-25 87.7 22.1 7.1e-18 64.3 6.7 3.6 3 1 0 3 3 3 2 Ion channel SPC25 PF06703.11 KIY49780.1 - 2.6 7.8 5.5 2.8 7.7 3.6 2.0 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Aldedh PF00171.22 KIY49782.1 - 1.1e-123 413.2 0.1 1.3e-123 412.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family tRNA-synt_2b PF00587.25 KIY49783.1 - 3.1e-38 131.5 0.1 6.5e-38 130.5 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIY49783.1 - 1.8e-21 76.4 9.0 1.8e-21 76.4 9.0 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain NuA4 PF09340.10 KIY49783.1 - 0.16 11.9 1.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 COG2 PF06148.11 KIY49783.1 - 0.27 11.3 2.4 0.46 10.6 1.0 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 KIY49783.1 - 0.3 10.3 3.1 0.55 9.4 3.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4820 PF16091.5 KIY49784.1 - 7.8 5.8 7.4 3.3 7.0 4.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) Gly_transf_sug PF04488.15 KIY49785.1 - 7.1e-06 26.6 0.0 2.4e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIY49785.1 - 0.027 13.8 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Kelch_6 PF13964.6 KIY49786.1 - 1.2e-12 47.7 8.2 3e-07 30.5 0.1 5.4 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KIY49786.1 - 2.1e-12 46.8 5.1 1.3e-05 25.1 0.1 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KIY49786.1 - 9.7e-09 35.3 4.3 0.00092 19.4 0.0 4.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KIY49786.1 - 1.4e-08 34.4 2.8 0.019 14.9 0.0 4.7 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KIY49786.1 - 2.1e-08 33.6 4.3 8.3e-05 22.1 0.0 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 KIY49786.1 - 6e-05 22.9 2.3 6.8 6.8 0.0 5.3 5 2 0 5 5 5 2 Kelch motif zf-C6H2 PF15801.5 KIY49786.1 - 0.0013 19.0 11.7 0.0028 17.9 11.7 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KIY49786.1 - 0.0049 16.9 9.1 0.012 15.7 9.1 1.6 1 0 0 1 1 1 1 MYND finger F-box PF00646.33 KIY49787.1 - 4.8e-05 23.1 0.1 0.00013 21.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY49787.1 - 0.00066 19.5 0.1 0.0017 18.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like SNF5 PF04855.12 KIY49789.1 - 5.7e-16 59.0 0.1 6e-16 59.0 0.1 1.0 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KIY49790.1 - 0.0003 20.3 3.1 0.0003 20.3 3.1 2.2 2 0 0 2 2 2 1 GATA zinc finger Nudix_N_2 PF14803.6 KIY49790.1 - 0.03 14.2 1.9 0.083 12.8 1.9 1.7 1 0 0 1 1 1 0 Nudix N-terminal Abhydrolase_6 PF12697.7 KIY49791.1 - 4.1e-08 34.1 3.1 5e-08 33.8 3.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY49791.1 - 0.026 13.8 0.0 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KIY49791.1 - 0.057 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 KIY49791.1 - 0.057 13.0 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PAPS_reduct PF01507.19 KIY49791.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family MTHFR PF02219.17 KIY49793.1 - 1e-101 340.1 0.0 1.4e-101 339.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Prenyltrans PF00432.21 KIY49794.1 - 2e-30 104.2 11.4 1.7e-06 27.6 0.5 6.0 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat HMG_box PF00505.19 KIY49795.1 - 0.0054 17.1 0.4 0.016 15.6 0.4 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HTH_Tnp_Tc3_2 PF01498.18 KIY49795.1 - 0.044 14.0 0.0 0.059 13.6 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE_1 PF03184.19 KIY49796.1 - 5e-22 78.4 0.0 9.2e-22 77.5 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIY49796.1 - 3.8e-05 23.5 0.0 0.0019 18.0 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Ndc1_Nup PF09531.10 KIY49797.1 - 5.6 5.5 4.9 6.5 5.3 4.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Plavaka PF18759.1 KIY49798.1 - 3.3e-29 102.1 0.0 5.3e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Abhydrolase_2 PF02230.16 KIY49799.1 - 6e-09 36.0 0.0 1.9e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KIY49799.1 - 0.005 17.5 0.9 0.0066 17.1 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box-like PF12937.7 KIY49800.1 - 2.8e-09 36.7 0.5 9.9e-09 35.0 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY49800.1 - 0.00013 21.7 0.1 0.0011 18.8 0.1 2.6 2 1 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KIY49800.1 - 0.19 12.2 0.4 9.5 6.8 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Sacchrp_dh_C PF16653.5 KIY49801.1 - 1.7e-83 280.8 0.0 3e-83 280.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 KIY49801.1 - 4.5e-66 221.8 0.0 9.1e-66 220.9 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 KIY49801.1 - 1.3e-25 90.2 1.3 6.6e-25 87.9 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 KIY49801.1 - 8e-24 83.3 0.9 1.5e-23 82.4 0.0 1.9 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Shikimate_DH PF01488.20 KIY49801.1 - 8.3e-07 29.1 0.0 1e-05 25.6 0.0 2.4 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 KIY49801.1 - 3.5e-05 24.4 0.0 0.00032 21.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY49801.1 - 0.0012 19.5 0.0 0.011 16.4 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain NAD_binding_10 PF13460.6 KIY49801.1 - 0.0017 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding YafO_toxin PF13957.6 KIY49802.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system PTPS_related PF10131.9 KIY49802.1 - 0.18 10.1 0.0 0.22 9.8 0.0 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DHC_N1 PF08385.12 KIY49803.1 - 2.4e-127 425.9 6.0 2.2e-126 422.8 1.6 2.3 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 GCIP PF13324.6 KIY49803.1 - 0.0042 16.7 1.5 0.011 15.3 0.1 2.3 3 0 0 3 3 3 1 Grap2 and cyclin-D-interacting BRX_N PF13713.6 KIY49804.1 - 0.1 12.4 1.0 0.23 11.3 0.7 1.8 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain MAGI_u5 PF16666.5 KIY49804.1 - 0.19 11.9 4.5 0.12 12.5 2.5 1.6 2 0 0 2 2 2 0 Unstructured region on MAGI WD40 PF00400.32 KIY49805.1 - 8.5e-09 35.9 10.0 0.031 15.2 0.2 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat Lactonase PF10282.9 KIY49805.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller NOA36 PF06524.12 KIY49805.1 - 0.093 12.0 6.5 0.16 11.3 6.5 1.3 1 0 0 1 1 1 0 NOA36 protein SET PF00856.28 KIY49806.1 - 2.8e-20 73.4 1.0 1.5e-19 71.0 0.1 2.3 2 1 0 2 2 2 1 SET domain N-SET PF11764.8 KIY49806.1 - 1e-09 38.7 7.6 1.9e-08 34.6 7.6 2.1 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N Barwin PF00967.17 KIY49807.1 - 0.011 15.5 0.1 0.013 15.3 0.1 1.1 1 0 0 1 1 1 0 Barwin family DPBB_1 PF03330.18 KIY49807.1 - 0.024 14.9 0.0 0.052 13.8 0.0 1.6 1 1 0 1 1 1 0 Lytic transglycolase TFIIB PF00382.19 KIY49808.1 - 2e-36 123.9 0.8 1.7e-18 66.4 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KIY49808.1 - 1.1e-19 70.6 14.0 7.9e-11 42.2 0.5 3.8 3 1 0 3 3 3 2 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KIY49808.1 - 1.6e-09 37.2 3.6 3.2e-09 36.2 3.6 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KIY49808.1 - 1.2e-05 25.1 0.3 0.0078 15.9 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-RRN7 PF11781.8 KIY49808.1 - 0.016 14.8 1.7 0.03 14.0 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 KIY49808.1 - 0.016 15.2 0.2 0.035 14.1 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 KIY49808.1 - 0.46 10.4 1.7 14 5.7 0.3 2.6 1 1 1 2 2 2 0 Nudix N-terminal CLTH PF10607.9 KIY49809.1 - 0.059 13.3 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain COX5A PF02284.16 KIY49810.1 - 1.5e-40 137.3 0.3 2.3e-40 136.8 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ApbA PF02558.16 KIY49811.1 - 1e-22 80.4 0.0 1.4e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KIY49811.1 - 3.2e-17 62.9 0.0 7.4e-15 55.3 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal MCR_C PF04609.12 KIY49811.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C ThiF PF00899.21 KIY49811.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_NADP PF03435.18 KIY49811.1 - 0.16 12.3 0.1 1.2 9.4 0.0 2.4 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain CRC_subunit PF08624.10 KIY49814.1 - 9.2e-40 136.2 0.0 1.4e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit ADK_lid PF05191.14 KIY49815.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid DUF3039 PF11238.8 KIY49815.1 - 0.073 12.8 0.4 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) TFIIS_C PF01096.18 KIY49818.1 - 8.4e-12 44.7 5.2 8.4e-12 44.7 5.2 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIY49818.1 - 2.4e-10 40.1 2.1 2.4e-10 40.1 2.1 3.8 3 1 1 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.6 KIY49818.1 - 0.00028 21.2 2.0 0.00028 21.2 2.0 2.0 2 1 0 2 2 2 1 Restriction alleviation protein Lar zf_UBZ PF18439.1 KIY49818.1 - 0.12 12.0 6.9 7.2 6.3 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Ribosomal_S27e PF01667.17 KIY49818.1 - 0.36 10.6 10.7 1.6 8.5 0.1 3.2 3 1 0 3 3 3 0 Ribosomal protein S27 zf-ribbon_3 PF13248.6 KIY49818.1 - 0.42 10.1 13.0 0.69 9.4 0.4 4.0 4 0 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.9 KIY49818.1 - 0.72 10.0 0.1 0.72 10.0 0.1 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-RRN7 PF11781.8 KIY49818.1 - 0.78 9.5 0.1 0.78 9.5 0.1 3.6 4 1 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 KIY49818.1 - 3.5 7.7 14.5 3 7.9 2.1 2.9 2 1 1 3 3 3 0 Double zinc ribbon Elf1 PF05129.13 KIY49818.1 - 4.8 7.3 12.0 1.4 9.1 4.4 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like HSP20 PF00011.21 KIY49819.1 - 0.00017 21.7 0.0 0.037 14.2 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family CSTF2_hinge PF14327.6 KIY49820.1 - 2.5e-27 95.1 3.0 2.5e-27 95.1 3.0 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KIY49820.1 - 1.4e-17 63.2 0.0 2.2e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KIY49820.1 - 6.8e-09 35.2 3.7 2.6e-08 33.3 3.7 2.1 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal DUF737 PF05300.11 KIY49820.1 - 0.67 10.3 4.9 1 9.7 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) TFIIA PF03153.13 KIY49820.1 - 1.8 8.5 7.6 2.2 8.2 7.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TBCC PF07986.12 KIY49822.1 - 2.2e-20 72.6 2.5 4e-20 71.7 2.5 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KIY49822.1 - 4.8e-10 39.9 0.6 1e-09 38.8 0.6 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Sugar_tr PF00083.24 KIY49823.1 - 5.4e-90 302.4 25.8 6.6e-90 302.1 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY49823.1 - 8.5e-27 94.0 69.4 8.1e-25 87.5 35.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_12 PF13424.6 KIY49825.1 - 5.8e-05 23.3 2.7 0.028 14.7 0.1 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIY49825.1 - 0.0025 17.6 1.5 0.58 10.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY49825.1 - 0.0063 16.5 0.1 3 8.2 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY49825.1 - 0.03 14.6 0.1 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KIY49825.1 - 0.035 14.9 8.5 10 7.3 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TMEM171 PF15471.6 KIY49825.1 - 0.041 12.9 0.3 0.1 11.6 0.3 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 Rap_GAP PF02145.15 KIY49826.1 - 8.6e-45 152.6 0.0 1.3e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KIY49826.1 - 5.9e-23 81.5 0.4 8.4e-23 81.0 0.4 1.2 1 0 0 1 1 1 1 Tuberin PHD_like PF12910.7 KIY49826.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system DUF4126 PF13548.6 KIY49827.1 - 0.03 14.0 0.2 0.093 12.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) Pkinase PF00069.25 KIY49828.1 - 1.5e-14 54.0 0.0 6.9e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KIY49828.1 - 5.9e-14 52.2 13.7 5.7e-07 30.1 0.3 6.9 7 0 0 7 7 7 2 WD domain, G-beta repeat HEAT PF02985.22 KIY49828.1 - 6e-12 44.7 14.1 0.044 14.1 0.1 6.1 5 0 0 5 5 5 5 HEAT repeat HEAT_2 PF13646.6 KIY49828.1 - 5.3e-06 26.7 0.5 0.44 11.0 0.0 3.9 2 2 2 4 4 4 3 HEAT repeats Pkinase_Tyr PF07714.17 KIY49828.1 - 9.5e-06 25.1 0.0 0.00017 20.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Cohesin_HEAT PF12765.7 KIY49828.1 - 0.038 14.3 1.6 2.1 8.8 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KIY49828.1 - 0.065 13.3 6.7 1.1 9.3 0.5 3.7 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 KIY49828.1 - 0.16 12.4 0.7 0.79 10.2 0.1 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain tRNA-synt_2b PF00587.25 KIY49829.1 - 6.2e-35 120.8 0.0 1.3e-34 119.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KIY49829.1 - 1.7e-19 69.7 0.1 3.5e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KIY49829.1 - 2e-14 53.4 0.0 1e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KIY49829.1 - 8.8e-12 44.9 0.0 1.6e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain ATPase_2 PF01637.18 KIY49830.1 - 3.6e-12 46.7 0.0 7e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KIY49830.1 - 5.6e-05 23.6 0.0 0.00011 22.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY49830.1 - 0.013 15.8 0.0 0.27 11.5 0.0 2.8 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 KIY49830.1 - 0.049 14.1 0.0 6.5 7.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UcrQ PF02939.16 KIY49831.1 - 5.1e-24 84.0 1.2 6.1e-24 83.8 1.2 1.1 1 0 0 1 1 1 1 UcrQ family FAD_binding_3 PF01494.19 KIY49832.1 - 1.8e-51 175.4 0.6 1.9e-26 93.1 0.1 3.2 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIY49832.1 - 1.1e-05 25.2 0.2 0.00094 18.9 0.2 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY49832.1 - 0.00013 21.3 0.2 0.083 12.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY49832.1 - 0.0005 20.6 0.9 0.43 11.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY49832.1 - 0.0011 19.2 0.1 0.0033 17.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Phe_hydrox_dim PF07976.12 KIY49832.1 - 0.0018 18.4 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KIY49832.1 - 0.027 13.2 0.5 0.96 8.1 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 KIY49832.1 - 0.063 12.9 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIY49832.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KIY49832.1 - 0.11 11.6 1.6 0.12 11.4 0.4 1.6 2 0 0 2 2 2 0 FAD binding domain DUF2269 PF10027.9 KIY49833.1 - 0.076 13.1 0.1 0.19 11.8 0.1 1.7 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF4743 PF15916.5 KIY49834.1 - 7.7e-10 38.8 0.0 2e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4743) NUDIX PF00293.28 KIY49834.1 - 0.0023 18.0 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ThiF PF00899.21 KIY49835.1 - 2.7e-41 141.5 0.0 4.5e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KIY49835.1 - 0.00056 20.2 1.8 0.007 16.6 1.0 2.6 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 KIY49835.1 - 0.0087 15.7 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KIY49835.1 - 0.0095 15.5 0.2 0.026 14.1 0.2 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KIY49835.1 - 0.041 13.5 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KIY49835.1 - 0.043 14.3 0.2 0.11 13.0 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KIY49835.1 - 0.056 12.7 0.4 0.096 11.9 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KIY49835.1 - 0.077 12.9 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY49835.1 - 0.11 11.8 0.2 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF543 PF04418.12 KIY49836.1 - 2.5e-18 65.8 0.2 2.8e-18 65.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-C2HC_2 PF13913.6 KIY49836.1 - 0.14 12.1 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type AIM5 PF17050.5 KIY49837.1 - 0.0044 17.8 0.0 0.009 16.8 0.0 1.5 1 1 1 2 2 2 1 Altered inheritance of mitochondria 5 BRO1 PF03097.18 KIY49838.1 - 8.5e-118 393.5 0.0 1.8e-117 392.5 0.0 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KIY49838.1 - 4.6e-57 193.6 3.9 7.5e-57 192.9 3.9 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV EST1_DNA_bind PF10373.9 KIY49840.1 - 6.3e-19 68.5 0.1 1.9e-18 67.0 0.2 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain SNF2_N PF00176.23 KIY49841.1 - 2.2e-69 233.9 0.2 3.6e-69 233.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY49841.1 - 3.8e-21 75.5 0.0 9.9e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIY49841.1 - 0.049 12.8 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RNHCP PF12647.7 KIY49841.1 - 0.068 13.2 0.3 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 RNHCP domain zf-C2HCIx2C PF10782.9 KIY49841.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger UDPG_MGDP_dh_N PF03721.14 KIY49842.1 - 4.4e-57 192.7 0.0 6.6e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KIY49842.1 - 2.5e-34 117.8 0.0 1.4e-33 115.5 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KIY49842.1 - 4.9e-30 103.6 0.0 9.2e-30 102.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Peptidase_M20 PF01546.28 KIY49843.1 - 2.9e-29 102.2 0.0 3.8e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY49843.1 - 5.6e-13 48.8 0.0 9.7e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY49843.1 - 0.00029 20.6 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 SUZ PF12752.7 KIY49844.1 - 3.3e-11 43.8 1.0 3.3e-11 43.8 1.0 2.3 2 0 0 2 2 2 1 SUZ domain COesterase PF00135.28 KIY49845.1 - 2.7e-91 307.0 0.1 3.5e-91 306.6 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY49845.1 - 1.6e-06 28.1 0.0 8e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold GDP_Man_Dehyd PF16363.5 KIY49846.1 - 9.6e-157 521.6 0.0 1.1e-156 521.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIY49846.1 - 4.8e-72 242.3 0.0 6.8e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY49846.1 - 0.00073 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY49846.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TPT PF03151.16 KIY49847.1 - 1.7e-13 50.6 21.0 2e-13 50.3 21.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIY49847.1 - 0.00016 21.8 40.0 0.00047 20.3 12.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family ADH_zinc_N PF00107.26 KIY49848.1 - 6.1e-11 42.4 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY49848.1 - 4.9e-08 32.8 0.0 9.5e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY49848.1 - 0.01 16.9 0.0 0.017 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BPL_N PF09825.9 KIY49849.1 - 2.8e-30 105.7 0.0 1.1e-20 74.1 0.0 2.8 2 1 1 3 3 3 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KIY49849.1 - 1.5e-21 76.7 0.0 2.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KIY49849.1 - 6e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DUF3887 PF13026.6 KIY49849.1 - 0.089 13.6 0.0 0.3 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) Proteasome PF00227.26 KIY49850.1 - 1.3e-13 50.8 1.1 4.9e-07 29.4 0.1 2.0 1 1 1 2 2 2 2 Proteasome subunit ArfGap PF01412.18 KIY49851.1 - 1.5e-40 137.9 0.4 2e-40 137.5 0.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PAPS_reduct PF01507.19 KIY49852.1 - 1.1e-31 110.2 0.0 1.5e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SPOB_ab PF14682.6 KIY49852.1 - 0.04 14.0 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Epimerase PF01370.21 KIY49853.1 - 2e-46 158.4 0.0 3e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY49853.1 - 9.1e-11 41.7 0.3 4.8e-10 39.3 0.3 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIY49853.1 - 0.047 12.8 0.0 0.2 10.7 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY49853.1 - 0.13 11.4 0.2 1.9 7.5 0.2 2.7 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1308 PF07000.11 KIY49854.1 - 0.00065 19.7 0.9 0.046 13.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1308) AAA_32 PF13654.6 KIY49854.1 - 0.051 12.3 0.1 0.073 11.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain DUF5572 PF17733.1 KIY49855.1 - 8.7e-18 63.9 0.6 8.9e-17 60.7 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5572) EST1_DNA_bind PF10373.9 KIY49856.1 - 1e-25 90.8 0.0 2.3e-25 89.7 0.0 1.6 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KIY49856.1 - 2.2e-18 67.2 0.0 1.8e-17 64.2 0.0 2.4 3 0 0 3 3 3 1 Telomerase activating protein Est1 TPR_2 PF07719.17 KIY49856.1 - 0.0061 16.6 0.6 0.085 13.0 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Pkinase_fungal PF17667.1 KIY49857.1 - 4e-28 98.3 0.0 2e-19 69.7 0.0 3.2 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 KIY49857.1 - 0.0011 18.9 1.1 0.13 12.2 0.6 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KIY49857.1 - 0.0043 16.4 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Mre11_DNA_bind PF04152.14 KIY49858.1 - 8.3e-50 169.4 0.2 8.3e-50 169.4 0.2 3.1 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KIY49858.1 - 2.3e-16 60.9 1.3 4.2e-16 60.0 1.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY49858.1 - 1e-06 29.0 1.2 2.6e-05 24.5 0.1 3.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_M3_N PF08439.10 KIY49858.1 - 0.098 12.9 0.6 0.26 11.6 0.6 1.7 1 0 0 1 1 1 0 Oligopeptidase F DIOX_N PF14226.6 KIY49859.1 - 2.8e-13 50.6 0.0 5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY49859.1 - 6e-13 49.1 0.0 1.6e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C3HC4_3 PF13920.6 KIY49860.1 - 5e-07 29.5 6.9 5e-07 29.5 6.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY49860.1 - 2.7e-06 27.3 6.8 3.8e-06 26.8 5.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY49860.1 - 4.4e-06 26.7 5.1 4.4e-06 26.7 5.1 2.7 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIY49860.1 - 1.6e-05 24.6 9.2 1.6e-05 24.6 9.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY49860.1 - 6.4e-05 22.8 7.4 6.4e-05 22.8 7.4 2.1 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIY49860.1 - 8.6e-05 22.3 4.7 8.6e-05 22.3 4.7 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY49860.1 - 0.0002 21.6 9.0 0.0002 21.6 9.0 2.2 2 1 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KIY49860.1 - 0.013 15.4 5.5 0.013 15.4 5.5 2.5 3 1 0 3 3 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KIY49860.1 - 0.033 14.0 0.2 0.033 14.0 0.2 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Tmpp129 PF10272.9 KIY49860.1 - 0.057 12.7 3.9 0.087 12.1 3.9 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor IBR PF01485.21 KIY49860.1 - 0.098 12.9 3.6 0.77 10.0 0.0 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_2 PF13240.6 KIY49860.1 - 0.22 11.3 4.4 3.9 7.3 1.0 3.0 2 1 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 KIY49860.1 - 3.3 7.9 5.7 24 5.1 0.3 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 MRG PF05712.13 KIY49862.1 - 1.7e-53 180.9 0.9 2.3e-53 180.4 0.9 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KIY49862.1 - 6e-11 42.1 0.8 1.2e-10 41.1 0.8 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Glyco_transf_15 PF01793.16 KIY49863.1 - 6.4e-120 400.3 9.0 1e-119 399.6 9.0 1.3 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Promethin PF16015.5 KIY49865.1 - 2.8e-09 36.8 20.7 3.8e-09 36.4 20.7 1.1 1 0 0 1 1 1 1 Promethin TPT PF03151.16 KIY49866.1 - 2.5e-38 132.1 19.8 3e-38 131.8 19.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KIY49866.1 - 4e-11 42.7 20.9 4.9e-11 42.4 20.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIY49866.1 - 4.2e-07 30.2 31.8 2.1e-05 24.7 10.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family GEN1_C PF18380.1 KIY49867.1 - 2e-29 102.6 0.2 4.5e-29 101.4 0.2 1.6 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KIY49867.1 - 6.7e-18 64.8 0.0 1.4e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIY49867.1 - 0.00014 22.3 0.0 0.00042 20.7 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain EF-hand_4 PF12763.7 KIY49867.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand zf-MYND PF01753.18 KIY49868.1 - 2.2e-06 27.6 11.7 3.6e-06 27.0 11.7 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY49868.1 - 0.22 11.9 4.6 0.36 11.2 4.6 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SNF2_N PF00176.23 KIY49869.1 - 6.5e-61 206.0 0.0 1e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY49869.1 - 4.3e-17 62.5 0.0 5.5e-16 58.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY49869.1 - 1.5e-07 31.6 0.0 2.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY49869.1 - 0.00026 20.8 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KIY49869.1 - 0.21 10.7 0.3 17 4.4 0.1 2.6 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Yip1 PF04893.17 KIY49871.1 - 0.032 14.0 27.3 0.22 11.3 26.8 2.0 1 1 1 2 2 2 0 Yip1 domain AA_permease_2 PF13520.6 KIY49872.1 - 1e-41 143.2 45.3 1.3e-41 142.9 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease GATA PF00320.27 KIY49874.1 - 4e-07 29.5 26.5 0.00018 21.0 8.3 2.6 2 0 0 2 2 2 2 GATA zinc finger CAP_N PF01213.19 KIY49877.1 - 0.27 10.7 5.4 0.28 10.6 5.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KIY49877.1 - 6 6.9 8.7 8.4 6.5 8.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 KDZ PF18758.1 KIY49878.1 - 1.2e-43 149.3 4.4 2.1e-43 148.5 4.4 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY49878.1 - 2e-27 95.5 0.3 6e-27 93.9 0.3 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY49878.1 - 0.00036 20.6 0.1 0.002 18.3 0.1 2.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Peptidase_G2 PF11962.8 KIY49878.1 - 0.14 11.5 0.0 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 Peptidase_G2, IMC autoproteolytic cleavage domain TEA PF01285.18 KIY49879.1 - 4.8e-05 23.3 0.0 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain DEAD PF00270.29 KIY49882.1 - 4.4e-13 49.4 0.0 7.1e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY49882.1 - 4.8e-09 36.6 0.0 2.1e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY49882.1 - 0.0023 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TetR_C_31 PF17940.1 KIY49883.1 - 0.11 12.8 0.1 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LOH1CR12 PF10158.9 KIY49885.1 - 0.06 13.4 0.7 0.18 11.8 0.2 1.8 2 0 0 2 2 2 0 Tumour suppressor protein Glyco_hydro_61 PF03443.14 KIY49886.1 - 2.9e-60 203.7 0.1 3.7e-60 203.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GMC_oxred_N PF00732.19 KIY49887.1 - 6.2e-23 81.6 0.0 1.5e-21 77.1 0.0 3.0 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY49887.1 - 1.1e-16 61.7 0.0 2.7e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIY49887.1 - 1.7e-08 34.0 0.7 0.00031 19.9 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KIY49887.1 - 5e-05 22.2 0.0 7.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KIY49887.1 - 0.00013 21.2 0.2 0.00051 19.2 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY49887.1 - 0.00045 19.5 0.2 0.0025 17.1 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY49887.1 - 0.00057 20.1 0.3 0.0015 18.7 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY49887.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIY49887.1 - 0.0014 18.3 0.0 0.0039 16.8 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KIY49887.1 - 0.0064 15.8 0.2 0.01 15.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KIY49887.1 - 0.013 16.0 1.8 0.13 12.9 0.3 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY49887.1 - 0.022 14.0 0.1 0.044 13.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KIY49887.1 - 0.025 13.9 1.7 0.18 11.1 0.9 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KIY49887.1 - 0.13 12.5 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 KIY49887.1 - 0.14 11.7 5.4 0.041 13.5 1.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Helitron_like_N PF14214.6 KIY49888.1 - 1.4e-20 74.3 0.0 1.8e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus ApoL PF05461.11 KIY49889.1 - 0.095 12.0 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein L SKN1 PF03935.15 KIY49890.1 - 6.9e-173 575.6 11.8 1.7e-171 571.1 11.8 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) RT_RNaseH PF17917.1 KIY49892.1 - 6.6e-07 29.6 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KIY49892.1 - 0.00083 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 KIY49894.1 - 9.4e-13 48.3 0.1 2.1e-12 47.2 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KIY49894.1 - 9.6e-07 28.5 0.1 2.2e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag_pre-integrs PF13976.6 KIY49895.1 - 5.5e-05 22.9 0.2 7.2e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Peptidase_C48 PF02902.19 KIY49896.1 - 2.3e-05 24.4 0.1 2.4e-05 24.3 0.1 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4254 PF14063.6 KIY49898.1 - 0.029 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Rab5-bind PF09311.11 KIY49899.1 - 0.036 13.5 0.3 7.3 5.9 0.0 2.1 2 0 0 2 2 2 0 Rabaptin-like protein JIP_LZII PF16471.5 KIY49899.1 - 0.063 13.4 4.0 7 6.9 0.1 3.1 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 KIY49899.1 - 0.099 12.9 9.3 0.75 10.1 0.9 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 KIY49899.1 - 0.37 10.6 5.5 4 7.3 0.0 2.6 3 0 0 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 KIY49899.1 - 0.7 10.0 5.7 9.2 6.4 0.5 3.3 3 0 0 3 3 3 0 Basic region leucine zipper NRBF2 PF08961.10 KIY49899.1 - 0.93 9.1 5.3 3.3 7.3 0.3 2.3 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator CHASE3 PF05227.13 KIY49899.1 - 1.2 9.1 5.2 8.8 6.2 0.3 2.5 2 0 0 2 2 2 0 CHASE3 domain Cnn_1N PF07989.11 KIY49899.1 - 1.2 9.3 4.2 4.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 KELK PF15796.5 KIY49899.1 - 1.9 9.0 7.8 1.6 9.3 0.8 2.9 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APG6_N PF17675.1 KIY49899.1 - 3.9 8.0 10.4 75 3.9 0.1 3.0 2 1 0 2 2 2 0 Apg6 coiled-coil region COX16 PF14138.6 KIY49900.1 - 8.9e-31 106.2 0.1 1.1e-30 106.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 VirB3 PF05101.13 KIY49900.1 - 0.027 14.7 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein CcmH PF03918.14 KIY49900.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF1682 PF07946.14 KIY49900.1 - 0.12 11.5 1.5 0.15 11.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GMC_oxred_N PF00732.19 KIY49901.1 - 4.9e-42 144.3 0.0 7.4e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY49901.1 - 4.6e-31 108.3 0.0 8.6e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Methyltransf_31 PF13847.6 KIY49902.1 - 1.5e-08 34.6 0.0 4.7e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY49902.1 - 1.1e-06 29.2 0.0 8.8e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 KIY49902.1 - 1.3e-05 25.7 0.0 3.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 PrmC N-terminal domain MTS PF05175.14 KIY49902.1 - 1.5e-05 24.6 1.1 0.00031 20.4 0.4 2.5 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KIY49902.1 - 0.0038 17.9 0.0 0.019 15.7 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY49902.1 - 0.0042 17.7 0.0 0.026 15.2 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 KIY49902.1 - 0.0043 16.5 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KIY49902.1 - 0.024 14.5 0.0 0.064 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_10 PF05971.12 KIY49902.1 - 0.028 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Adeno_shaft PF00608.17 KIY49902.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) PsbQ PF05757.11 KIY49903.1 - 0.082 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) F-box-like PF12937.7 KIY49904.1 - 9.8e-06 25.4 0.0 7.2e-05 22.6 0.0 2.5 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY49905.1 - 0.0026 17.6 0.0 0.0026 17.6 0.0 3.2 4 1 0 4 4 4 1 F-box-like Clathrin PF00637.20 KIY49906.1 - 4.7e-19 68.7 0.2 7.3e-14 51.9 0.4 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KIY49906.1 - 1e-11 44.9 0.5 2.3e-11 43.8 0.5 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KIY49906.1 - 3.4e-08 33.4 8.7 5.9e-08 32.6 8.7 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KIY49906.1 - 0.0091 15.8 8.1 0.016 15.1 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY49906.1 - 0.13 12.7 8.2 0.23 11.8 8.2 1.4 1 0 0 1 1 1 0 Ring finger domain TPR_2 PF07719.17 KIY49906.1 - 0.22 11.7 0.9 1.3 9.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 KIY49906.1 - 0.57 10.2 7.8 1 9.4 7.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TPR_16 PF13432.6 KIY49906.1 - 2.9 8.6 5.4 1.4 9.6 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 KIY49906.1 - 3.7 7.7 7.3 7.4 6.7 7.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Hist_deacetyl PF00850.19 KIY49909.1 - 2.5e-64 217.7 0.0 3.2e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HJURP_mid PF12346.8 KIY49910.1 - 0.03 14.8 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat Phage_int_SAM_3 PF14659.6 KIY49911.1 - 0.014 15.7 0.0 0.045 14.0 0.0 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF3884 PF13024.6 KIY49911.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) DUF4962 PF16332.5 KIY49912.1 - 0.0022 16.6 0.0 0.0037 15.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) DUF1752 PF08550.10 KIY49916.1 - 2.4e-08 33.6 9.0 2.4e-08 33.6 9.0 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) YL1 PF05764.13 KIY49916.1 - 0.025 14.7 5.6 0.055 13.6 5.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KIY49916.1 - 1.3 7.3 7.2 1.8 6.8 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KIY49917.1 - 5.3e-18 65.1 23.5 9.3e-15 54.4 21.1 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF998 PF06197.13 KIY49917.1 - 6.1 6.4 18.1 0.041 13.5 5.7 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF998) ZZ PF00569.17 KIY49918.1 - 1.2e-24 85.8 49.4 4.8e-08 32.7 4.6 5.2 5 0 0 5 5 5 5 Zinc finger, ZZ type C1_2 PF03107.16 KIY49918.1 - 4.3e-06 26.9 52.7 0.02 15.2 8.0 5.4 5 1 0 5 5 5 4 C1 domain zf-CCHC_4 PF14392.6 KIY49918.1 - 0.034 13.9 2.7 0.086 12.6 0.3 3.0 2 0 0 2 2 2 0 Zinc knuckle DUF35_N PF12172.8 KIY49918.1 - 0.66 9.9 14.6 0.37 10.7 0.5 3.9 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PB1 PF00564.24 KIY49919.1 - 3.1e-10 39.8 0.1 5.1e-10 39.1 0.1 1.5 1 1 0 1 1 1 1 PB1 domain LisH PF08513.11 KIY49920.1 - 2.9e-05 23.8 0.1 3.6e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 LisH Phos_pyr_kin PF08543.12 KIY49921.1 - 3.6e-10 39.7 0.0 6.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KIY49921.1 - 0.0024 17.3 0.2 0.0067 15.8 0.0 1.8 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Glyco_transf_24 PF18404.1 KIY49922.1 - 2.4e-144 479.7 1.2 3.4e-144 479.2 1.2 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KIY49922.1 - 9.6e-65 219.0 0.0 1.2e-63 215.4 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KIY49922.1 - 5.4e-49 166.7 0.0 1.5e-48 165.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KIY49922.1 - 1e-37 129.0 1.1 5.3e-37 126.8 0.4 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KIY49922.1 - 7.4e-34 116.1 0.0 1.6e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 KIY49922.1 - 7.2e-31 107.8 0.0 3.4e-30 105.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KIY49922.1 - 1.2e-05 25.0 0.1 2.3e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 CSN5_C PF18323.1 KIY49923.1 - 2.5e-26 92.4 2.8 4.5e-26 91.6 2.8 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain JAB PF01398.21 KIY49923.1 - 6.5e-26 90.6 0.0 1.1e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KIY49923.1 - 0.0077 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3236 PF11576.8 KIY49923.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) DEAD PF00270.29 KIY49924.1 - 7.7e-14 51.8 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KIY49924.1 - 5.3e-08 33.5 3.8 6.6e-08 33.2 0.1 3.0 3 0 0 3 3 3 1 RecQ zinc-binding Helicase_C PF00271.31 KIY49924.1 - 0.00089 19.6 0.1 0.53 10.7 0.1 2.6 1 1 1 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIY49924.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KIY49925.1 - 2.9e-11 43.2 4.1 2.9e-11 43.2 4.1 2.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY49925.1 - 1.3e-10 41.3 8.6 3.6e-10 39.8 8.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIY49925.1 - 8.6e-10 38.3 9.4 1.9e-09 37.3 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY49925.1 - 1.7e-09 37.4 7.9 1.7e-09 37.4 7.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY49925.1 - 2.3e-09 37.4 9.3 6.2e-09 36.1 9.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY49925.1 - 4.4e-09 36.0 9.6 2e-08 34.0 9.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY49925.1 - 9e-08 32.0 8.0 2e-07 30.9 8.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY49925.1 - 3.4e-05 23.6 8.6 7.6e-05 22.5 8.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIY49925.1 - 0.00012 21.8 5.8 0.00038 20.2 5.8 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KIY49925.1 - 0.0074 16.1 7.1 0.017 15.0 7.1 1.7 1 1 0 1 1 1 1 zf-RING of BARD1-type protein FYVE PF01363.21 KIY49925.1 - 0.027 14.6 4.4 0.027 14.6 1.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_11 PF17123.5 KIY49925.1 - 0.027 14.2 8.9 0.027 14.2 8.9 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-UDP PF14569.6 KIY49925.1 - 0.03 14.5 3.6 0.052 13.7 3.6 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc_ribbon_9 PF14369.6 KIY49925.1 - 0.034 14.4 3.4 0.073 13.3 3.4 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-ANAPC11 PF12861.7 KIY49925.1 - 0.12 12.4 2.7 0.25 11.4 2.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY49925.1 - 0.2 11.9 10.7 0.077 13.3 7.2 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain DZR PF12773.7 KIY49925.1 - 0.7 10.0 8.9 0.3 11.1 5.1 2.3 2 1 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.8 KIY49925.1 - 2.3 8.1 7.1 4.2 7.3 7.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ubiquitin PF00240.23 KIY49926.1 - 2.7e-34 116.8 0.4 3e-34 116.6 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIY49926.1 - 5.1e-15 55.1 0.3 5.7e-15 54.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIY49926.1 - 6.9e-06 26.4 0.1 3.1e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KIY49926.1 - 0.0019 18.1 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KIY49926.1 - 0.002 18.5 0.1 0.0022 18.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY49926.1 - 0.0031 17.6 0.1 0.0072 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KIY49926.1 - 0.018 15.1 0.2 2.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KIY49926.1 - 0.02 15.5 0.1 0.023 15.2 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_L5 PF00281.19 KIY49927.1 - 1.4e-21 76.5 0.1 3.4e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KIY49927.1 - 6.1e-21 74.4 0.0 9.8e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Rxt3 PF08642.10 KIY49928.1 - 1.4e-05 25.9 0.0 1.5e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 TLE_N PF03920.15 KIY49929.1 - 0.0087 16.1 0.2 0.023 14.8 0.2 1.7 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HALZ PF02183.18 KIY49929.1 - 0.012 15.8 0.6 0.042 14.1 0.6 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper UPF0242 PF06785.11 KIY49929.1 - 0.3 11.2 12.6 0.21 11.7 0.3 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 KIY49929.1 - 0.31 11.0 7.1 0.55 10.2 7.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 KIY49929.1 - 0.57 10.6 10.8 0.82 10.1 2.3 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FUSC PF04632.12 KIY49929.1 - 3 6.3 4.4 5.2 5.5 4.4 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family MAD PF05557.13 KIY49930.1 - 7.3e-47 160.1 58.6 1.4e-44 152.6 58.6 2.8 1 1 0 1 1 1 1 Mitotic checkpoint protein Atg14 PF10186.9 KIY49930.1 - 0.0015 17.7 7.4 0.0015 17.7 7.4 3.6 1 1 4 5 5 5 1 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 KIY49930.1 - 0.0044 16.4 64.6 0.66 9.3 2.2 5.6 3 2 2 5 5 5 4 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 KIY49930.1 - 0.2 9.2 54.5 0.019 12.5 12.6 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KIY49930.1 - 6.1 6.1 46.8 0.12 11.7 2.9 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) FapA PF03961.13 KIY49930.1 - 6.8 5.2 40.5 0.95 8.0 0.2 5.0 2 1 2 5 5 5 0 Flagellar Assembly Protein A Yae1_N PF09811.9 KIY49931.1 - 6.7e-11 41.7 2.4 1.3e-10 40.8 2.4 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RhoGEF PF00621.20 KIY49932.1 - 1.2e-66 224.4 5.3 1.9e-36 126.0 2.4 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 KIY49932.1 - 2.9e-57 194.4 0.0 4.4e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIY49932.1 - 8.6e-18 64.7 0.0 1.7e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KIY49932.1 - 5.6e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KIY49932.1 - 0.0018 18.1 0.0 0.008 16.0 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIY49932.1 - 0.0078 16.7 0.0 0.041 14.4 0.0 2.2 1 1 0 1 1 1 1 PH domain Fez1 PF06818.15 KIY49933.1 - 0.68 10.3 34.0 1.5e+03 -0.5 32.6 2.8 2 1 0 2 2 2 0 Fez1 Jnk-SapK_ap_N PF09744.9 KIY49933.1 - 1 9.5 35.2 1.6 8.9 6.4 3.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF4047 PF13256.6 KIY49933.1 - 2.8 8.1 7.8 0.74 10.0 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Lebercilin PF15619.6 KIY49933.1 - 4.3 6.9 34.1 2.2 7.9 28.7 2.7 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease IZUMO PF15005.6 KIY49933.1 - 6.9 7.2 12.0 12 6.4 1.1 2.8 1 1 1 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated UFD1 PF03152.14 KIY49934.1 - 7.4e-70 233.9 0.0 9.3e-70 233.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KIY49934.1 - 0.007 16.1 0.0 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 CNH PF00780.22 KIY49935.1 - 7.8e-60 202.8 0.0 3.5e-59 200.7 0.0 1.9 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 KIY49935.1 - 6e-53 179.8 0.1 8.2e-28 97.9 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain PH_5 PF15405.6 KIY49935.1 - 1.8e-20 73.4 0.0 4e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIY49935.1 - 5e-05 23.7 0.0 0.00014 22.3 0.0 1.8 1 0 0 1 1 1 1 PH domain DEP PF00610.21 KIY49935.1 - 0.0035 17.4 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KIY49935.1 - 0.0098 15.7 0.0 0.06 13.2 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Ribonuc_P_40 PF08584.11 KIY49938.1 - 7.4e-25 87.8 0.0 3.3e-24 85.7 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit DUF442 PF04273.13 KIY49938.1 - 0.051 13.7 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative phosphatase (DUF442) HMG_CoA_synt_C PF08540.10 KIY49939.1 - 1.5e-85 287.3 0.0 2.1e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KIY49939.1 - 4.3e-83 277.4 0.0 6e-83 277.0 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3641 PF12345.8 KIY49939.1 - 0.1 12.6 0.0 5 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) Amnionless PF14828.6 KIY49940.1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Glt_symporter PF03616.14 KIY49940.1 - 0.086 11.5 0.2 0.11 11.2 0.2 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter FAD-oxidase_C PF02913.19 KIY49941.1 - 8.8e-55 186.0 0.0 2.3e-54 184.7 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIY49941.1 - 2.4e-29 101.8 0.0 4.3e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HEAT_EZ PF13513.6 KIY49942.1 - 4.4e-06 27.1 22.0 0.011 16.2 0.5 8.1 8 0 0 8 8 8 3 HEAT-like repeat HEAT PF02985.22 KIY49942.1 - 6.2e-06 26.0 15.5 0.3 11.4 0.1 10.0 10 0 0 10 10 10 1 HEAT repeat Arm PF00514.23 KIY49942.1 - 0.002 18.1 1.2 0.026 14.5 0.1 3.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KIY49942.1 - 0.0021 18.4 22.1 1.9 8.9 0.1 8.4 7 1 1 8 8 8 2 HEAT repeats Adaptin_N PF01602.20 KIY49942.1 - 0.0094 14.6 3.3 0.054 12.1 0.0 3.5 4 0 0 4 4 4 1 Adaptin N terminal region RTP1_C1 PF10363.9 KIY49942.1 - 0.013 15.7 1.3 15 5.8 0.0 4.7 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Polysacc_deac_1 PF01522.21 KIY49943.1 - 5.7e-28 97.3 0.0 9.2e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KIY49943.1 - 0.00016 21.0 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 ATP-grasp_4 PF13535.6 KIY49943.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain PGM_PMM_I PF02878.16 KIY49945.1 - 2.8e-36 124.3 0.2 4.3e-36 123.6 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KIY49945.1 - 6.1e-26 90.9 0.0 1.2e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KIY49945.1 - 8.2e-16 58.5 0.0 3.9e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KIY49945.1 - 5.7e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2460 PF09343.10 KIY49945.1 - 0.00083 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 2217 (DUF2460) BCS1_N PF08740.11 KIY49946.1 - 1.6e-19 70.6 3.3 2e-18 67.1 3.3 2.1 1 1 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KIY49946.1 - 8.9e-14 52.0 0.0 1.3e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY49946.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 KIY49946.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KIY49946.1 - 0.058 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KIY49946.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIY49946.1 - 0.067 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PAP2 PF01569.21 KIY49947.1 - 7.8e-11 41.9 8.5 2.2e-10 40.5 7.7 2.0 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KIY49947.1 - 0.066 13.3 0.0 0.63 10.2 0.0 2.1 1 1 1 2 2 2 0 Divergent PAP2 family Polysacc_synt_C PF14667.6 KIY49947.1 - 4.8 7.2 8.8 10 6.2 8.8 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF4598 PF15370.6 KIY49948.1 - 5.1e-16 59.1 3.5 5.6e-16 59.0 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Dus PF01207.17 KIY49949.1 - 5.2e-75 252.4 0.0 6.6e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 KIY49949.1 - 8e-05 22.2 0.1 0.00024 20.6 0.1 1.6 1 1 1 2 2 2 1 Nitronate monooxygenase SOR_SNZ PF01680.17 KIY49949.1 - 0.00023 21.0 0.1 0.018 14.8 0.1 2.3 1 1 1 2 2 2 2 SOR/SNZ family FMN_dh PF01070.18 KIY49949.1 - 0.00024 20.2 0.0 0.00032 19.8 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KIY49949.1 - 0.068 12.4 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Pantoate_ligase PF02569.15 KIY49950.1 - 9.6e-92 307.0 0.0 1.1e-91 306.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase AP_endonuc_2 PF01261.24 KIY49950.1 - 0.013 15.0 0.0 0.32 10.4 0.0 2.2 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel VPS9 PF02204.18 KIY49951.1 - 4.8e-30 103.8 0.1 8.8e-30 103.0 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KIY49951.1 - 9.4e-18 64.3 0.3 3.1e-17 62.6 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KIY49951.1 - 9e-10 38.1 0.2 4.8e-09 35.7 0.1 2.3 3 0 0 3 3 3 1 CUE domain DMA PF03474.14 KIY49951.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif GPI-anchored PF10342.9 KIY49953.1 - 0.0011 19.6 0.6 0.0011 19.6 0.6 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ADH_N PF08240.12 KIY49955.1 - 1.9e-24 85.6 0.3 3.7e-24 84.7 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY49955.1 - 1.7e-15 57.2 0.0 2.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY49955.1 - 1.4e-05 24.7 0.0 2.9e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIY49955.1 - 0.05 14.6 0.0 0.095 13.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Mus7 PF09462.10 KIY49956.1 - 1.4 7.7 3.5 7.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Mus7/MMS22 family DDE_3 PF13358.6 KIY49957.1 - 0.036 13.8 0.0 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease Amidohydro_1 PF01979.20 KIY49958.1 - 1.9e-26 93.2 0.0 7.4e-26 91.3 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIY49958.1 - 4.8e-17 62.6 0.1 1.3e-07 31.5 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 KIY49958.1 - 0.0093 16.3 0.7 0.028 14.8 0.3 1.9 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain PMT PF02366.18 KIY49959.1 - 6.7e-84 281.3 18.3 6.7e-84 281.3 18.3 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIY49959.1 - 2.9e-60 203.3 5.3 2.9e-60 203.3 5.3 3.4 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIY49959.1 - 1.5e-17 64.1 0.1 1.5e-17 64.1 0.1 1.5 2 0 0 2 2 2 1 MIR domain PMT_2 PF13231.6 KIY49959.1 - 6.2e-08 33.0 13.8 1.7e-07 31.6 12.5 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1240 PF06836.12 KIY49959.1 - 0.26 11.9 2.9 67 4.1 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) PX PF00787.24 KIY49960.1 - 1.1e-13 51.1 0.0 2.5e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 PX domain AvrRpt-cleavage PF05627.11 KIY49960.1 - 0.55 9.6 1.8 1.1 8.7 1.8 1.5 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr Asp PF00026.23 KIY49961.1 - 1.6e-65 221.6 0.8 1.9e-65 221.4 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY49961.1 - 3.5e-08 33.9 0.7 1.1e-05 25.8 0.7 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIY49961.1 - 7.2e-05 22.6 0.1 0.0018 18.1 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal ubiquitin PF00240.23 KIY49962.1 - 3.4e-34 116.4 0.5 3.4e-34 116.4 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KIY49962.1 - 2.1e-26 91.8 1.5 2.1e-26 91.8 1.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KIY49962.1 - 3.8e-16 58.7 0.6 7.9e-16 57.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIY49962.1 - 2.8e-05 24.5 0.4 0.00014 22.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY49962.1 - 0.00031 20.8 0.6 0.00068 19.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KIY49962.1 - 0.0054 17.3 0.7 0.0077 16.8 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KIY49962.1 - 0.007 16.7 0.9 0.012 15.9 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KIY49962.1 - 0.0073 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 KIY49962.1 - 0.02 14.9 1.1 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 KIY49962.1 - 0.024 14.8 0.5 0.042 14.1 0.5 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF4925 PF16272.5 KIY49962.1 - 0.078 12.4 0.3 0.11 12.0 0.3 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4925) DUF971 PF06155.12 KIY49962.1 - 0.16 12.6 0.2 0.36 11.5 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF971) PgaD PF13994.6 KIY49963.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein Ank_2 PF12796.7 KIY49965.1 - 2.5e-12 47.2 1.6 3.3e-05 24.4 0.1 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY49965.1 - 8e-10 38.1 3.6 0.0019 18.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KIY49965.1 - 7.9e-09 35.9 1.3 2.4e-06 28.0 0.3 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY49965.1 - 6.1e-08 32.8 0.9 0.016 15.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KIY49965.1 - 2.2e-06 27.8 9.7 0.0005 20.4 0.3 3.9 3 1 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 KIY49965.1 - 0.00011 22.0 1.0 0.00087 19.1 0.1 2.5 2 1 0 2 2 2 1 KilA-N domain Lebercilin PF15619.6 KIY49965.1 - 0.06 13.0 1.2 0.15 11.7 1.2 1.6 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease OmpH PF03938.14 KIY49965.1 - 0.54 10.6 4.9 0.99 9.7 4.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MAD PF05557.13 KIY49965.1 - 1.4 7.2 5.1 0.25 9.7 1.4 1.5 2 0 0 2 2 2 0 Mitotic checkpoint protein Pkinase PF00069.25 KIY49967.1 - 2.7e-60 204.0 0.0 2.6e-59 200.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY49967.1 - 3e-23 82.4 0.3 1.8e-17 63.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY49967.1 - 7.8e-05 21.8 0.0 0.00013 21.0 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KIY49967.1 - 0.005 15.9 0.0 0.0091 15.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KIY49967.1 - 0.0056 16.0 0.3 0.025 14.0 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY49967.1 - 0.013 14.9 1.9 0.024 14.0 0.2 2.3 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 KIY49967.1 - 0.025 14.5 1.8 0.92 9.4 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY49967.1 - 0.033 13.0 0.1 0.049 12.4 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase Rep_fac_C PF08542.11 KIY49968.1 - 2.2e-19 69.6 0.0 6.2e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KIY49968.1 - 1.5e-16 61.1 0.0 2.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KIY49968.1 - 3.4e-14 53.0 0.0 4.5e-10 39.5 0.0 2.4 2 1 1 3 3 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KIY49968.1 - 2.4e-10 40.7 0.0 3.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KIY49968.1 - 9.3e-07 28.7 0.1 4e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KIY49968.1 - 2e-06 27.9 0.1 1e-05 25.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KIY49968.1 - 1.3e-05 25.0 0.0 6e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KIY49968.1 - 1.8e-05 24.0 0.0 4.7e-05 22.7 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KIY49968.1 - 5.9e-05 23.0 0.3 0.00033 20.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KIY49968.1 - 0.00014 22.3 0.0 0.00026 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KIY49968.1 - 0.0002 21.1 0.0 0.00081 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KIY49968.1 - 0.00023 21.4 0.2 0.00093 19.5 0.2 2.2 1 1 0 1 1 1 1 AAA C-terminal domain DEAD PF00270.29 KIY49968.1 - 0.00035 20.4 0.8 0.0025 17.6 1.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY49968.1 - 0.0005 20.4 0.7 0.012 15.9 0.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY49968.1 - 0.00053 20.4 1.4 0.015 15.6 0.3 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KIY49968.1 - 0.00071 19.6 0.5 0.0087 16.1 0.1 2.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIY49968.1 - 0.00094 19.0 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KIY49968.1 - 0.0021 18.1 0.1 0.011 15.8 0.1 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KIY49968.1 - 0.0024 17.4 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 KIY49968.1 - 0.0055 15.8 0.1 0.019 14.0 0.0 1.8 1 1 1 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KIY49968.1 - 0.0067 16.2 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KIY49968.1 - 0.018 15.6 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIY49968.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KIY49968.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 KIY49968.1 - 0.025 14.0 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 KIY49968.1 - 0.03 13.7 0.0 0.08 12.3 0.0 1.7 1 1 0 1 1 1 0 Bacterial TniB protein TPR_6 PF13174.6 KIY49968.1 - 0.033 14.8 3.0 0.25 12.0 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_25 PF13481.6 KIY49968.1 - 0.038 13.5 0.0 0.09 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIY49968.1 - 0.045 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea STD1 PF17235.2 KIY49968.1 - 0.053 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 STD1/MTH1 IstB_IS21 PF01695.17 KIY49968.1 - 0.075 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein SRP54 PF00448.22 KIY49968.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DNA_pol3_delta PF06144.13 KIY49968.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_33 PF13671.6 KIY49968.1 - 0.098 12.8 0.3 0.27 11.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIY49968.1 - 0.15 12.6 0.0 0.57 10.7 0.0 2.0 2 1 0 2 2 2 0 ABC transporter Methyltransf_23 PF13489.6 KIY49969.1 - 6.6e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY49969.1 - 2.8e-05 24.7 0.0 0.025 15.3 0.0 3.0 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 KIY49969.1 - 0.0062 17.2 0.0 0.14 12.8 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain F-box-like PF12937.7 KIY49970.1 - 0.097 12.6 2.3 0.49 10.3 0.5 2.7 2 0 0 2 2 2 0 F-box-like Cript PF10235.9 KIY49971.1 - 2.9e-27 95.0 5.1 2.9e-27 95.0 5.1 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KIY49971.1 - 5.6e-05 23.1 6.1 0.00028 20.9 3.6 2.2 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KIY49971.1 - 0.013 15.2 13.2 2.3 8.1 0.0 3.5 3 1 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KIY49971.1 - 0.042 13.3 6.5 1.4 8.4 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Gin PF10764.9 KIY49971.1 - 0.047 13.6 8.9 0.35 10.8 0.0 3.2 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin Baculo_RING PF05883.11 KIY49971.1 - 0.074 13.0 1.4 3.6 7.6 0.6 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zinc_ribbon_15 PF17032.5 KIY49971.1 - 0.12 13.1 12.8 0.38 11.5 10.2 2.4 2 1 0 2 2 2 0 zinc-ribbon family PolC_DP2 PF03833.13 KIY49971.1 - 0.25 9.2 4.8 0.24 9.2 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF4428 PF14471.6 KIY49971.1 - 0.47 10.4 0.2 0.47 10.4 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4428) DUF2039 PF10217.9 KIY49971.1 - 0.48 10.8 13.7 0.88 10.0 10.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 KIY49971.1 - 0.99 9.4 13.3 7.5 6.6 13.3 2.1 1 1 0 1 1 1 0 zinc-ribbons NOB1_Zn_bind PF08772.11 KIY49971.1 - 5.4 7.3 12.2 3.7 7.8 4.8 2.9 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-dskA_traR PF01258.17 KIY49971.1 - 5.7 7.0 13.0 1.5 8.8 0.1 3.9 3 2 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zf_UBZ PF18439.1 KIY49971.1 - 7.4 6.3 9.8 6.8 6.4 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 KIY49971.1 - 8.4 6.5 9.8 2 8.4 4.4 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SNF2_N PF00176.23 KIY49972.1 - 3.4e-14 52.3 0.4 4.9e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KIY49972.1 - 5.4e-12 45.7 0.0 1.4e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KIY49972.1 - 2.7e-07 30.9 0.0 7.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY49972.1 - 6.8e-05 22.9 0.3 0.0023 17.9 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-B_box PF00643.24 KIY49972.1 - 0.018 15.2 1.6 0.072 13.3 1.6 2.0 1 0 0 1 1 1 0 B-box zinc finger zf-RING_5 PF14634.6 KIY49972.1 - 1.5 8.8 24.5 1.6 8.7 11.8 3.5 4 0 0 4 4 4 0 zinc-RING finger domain PET117 PF15786.5 KIY49973.1 - 2.8e-23 81.9 1.4 3.2e-23 81.8 1.4 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Glyco_hydro_16 PF00722.21 KIY49974.1 - 9.9e-07 28.4 0.0 2.9e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 ELFV_dehydrog_N PF02812.18 KIY49974.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CTD_bind PF04818.13 KIY49975.1 - 4.1e-10 40.3 0.0 9.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PAP2 PF01569.21 KIY49976.1 - 3.8e-27 94.7 1.2 3.8e-27 94.7 1.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily DWNN PF08783.11 KIY49977.1 - 2.6e-27 94.9 0.1 4.8e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KIY49977.1 - 1.8e-09 37.2 4.5 3.6e-09 36.3 4.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY49977.1 - 7.1e-07 29.0 1.7 7.1e-07 29.0 1.7 1.7 2 0 0 2 2 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 KIY49977.1 - 0.00033 20.4 6.4 0.00033 20.4 6.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 KIY49977.1 - 0.00058 19.8 0.7 0.0013 18.6 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KIY49977.1 - 0.0028 17.5 11.7 0.0028 17.5 11.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf_C2H2_10 PF18414.1 KIY49977.1 - 0.0049 16.4 0.3 0.012 15.2 0.3 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger zf-RING_2 PF13639.6 KIY49977.1 - 0.0053 17.1 9.0 0.0053 17.1 9.0 1.8 2 0 0 2 2 1 1 Ring finger domain zf-CCHC_5 PF14787.6 KIY49977.1 - 0.0054 16.4 0.6 0.0054 16.4 0.6 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-C3HC4 PF00097.25 KIY49977.1 - 0.017 15.0 10.9 0.039 13.8 10.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.16 KIY49977.1 - 0.024 15.2 1.0 0.066 13.8 0.1 2.2 2 0 0 2 2 2 0 Trm112p-like protein PP_kinase_C PF13090.6 KIY49977.1 - 0.12 11.9 0.1 0.64 9.5 0.1 2.0 1 1 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 zf_UBZ PF18439.1 KIY49977.1 - 0.29 10.8 0.1 0.29 10.8 0.1 3.1 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger zf-Nse PF11789.8 KIY49977.1 - 0.53 10.2 5.5 1.2 9.0 5.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KIY49977.1 - 0.64 10.1 8.4 1.4 9.0 8.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 KIY49977.1 - 3.1 7.9 10.9 2.7 8.1 5.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon RVT_1 PF00078.27 KIY49980.1 - 1.8e-07 30.9 0.1 3.4e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DWNN PF08783.11 KIY49981.1 - 2.6e-27 94.9 0.1 4.8e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KIY49981.1 - 1.8e-09 37.2 4.5 3.6e-09 36.3 4.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY49981.1 - 7.1e-07 29.0 1.7 7.1e-07 29.0 1.7 1.7 2 0 0 2 2 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 KIY49981.1 - 0.00033 20.4 6.4 0.00033 20.4 6.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 KIY49981.1 - 0.00058 19.8 0.7 0.0013 18.6 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KIY49981.1 - 0.0028 17.5 11.7 0.0028 17.5 11.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf_C2H2_10 PF18414.1 KIY49981.1 - 0.0049 16.4 0.3 0.012 15.2 0.3 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger zf-RING_2 PF13639.6 KIY49981.1 - 0.0053 17.1 9.0 0.0053 17.1 9.0 1.8 2 0 0 2 2 1 1 Ring finger domain zf-CCHC_5 PF14787.6 KIY49981.1 - 0.0054 16.4 0.6 0.0054 16.4 0.6 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-C3HC4 PF00097.25 KIY49981.1 - 0.017 15.0 10.9 0.039 13.8 10.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.16 KIY49981.1 - 0.024 15.2 1.0 0.066 13.8 0.1 2.2 2 0 0 2 2 2 0 Trm112p-like protein PP_kinase_C PF13090.6 KIY49981.1 - 0.12 11.9 0.1 0.64 9.5 0.1 2.0 1 1 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 zf_UBZ PF18439.1 KIY49981.1 - 0.29 10.8 0.1 0.29 10.8 0.1 3.1 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger zf-Nse PF11789.8 KIY49981.1 - 0.53 10.2 5.5 1.2 9.0 5.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KIY49981.1 - 0.64 10.1 8.4 1.4 9.0 8.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 KIY49981.1 - 3.1 7.9 10.9 2.7 8.1 5.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon KAR9 PF08580.10 KIY49982.1 - 3.4e-17 62.3 53.6 7.7e-16 57.8 51.8 3.8 1 1 1 2 2 2 1 Yeast cortical protein KAR9 GAS2 PF02187.17 KIY49982.1 - 3.8e-05 23.7 0.2 9.2e-05 22.5 0.2 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain PAPA-1 PF04795.12 KIY49982.1 - 0.024 15.4 0.4 0.059 14.2 0.4 1.7 1 0 0 1 1 1 0 PAPA-1-like conserved region Syntaxin-6_N PF09177.11 KIY49982.1 - 2.3 8.8 7.2 2 9.0 0.2 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal LMBR1 PF04791.16 KIY49984.1 - 1e-05 24.7 1.9 1.2e-05 24.4 1.9 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Tropomyosin_1 PF12718.7 KIY49984.1 - 0.00032 20.9 1.5 0.00043 20.4 1.5 1.2 1 0 0 1 1 1 1 Tropomyosin like DUF4407 PF14362.6 KIY49984.1 - 0.0013 18.2 0.1 0.0017 17.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) APG17 PF04108.12 KIY49984.1 - 0.0035 16.5 1.2 0.0035 16.5 1.2 1.4 2 0 0 2 2 2 1 Autophagy protein Apg17 Laminin_II PF06009.12 KIY49984.1 - 0.0065 16.5 4.1 0.01 15.9 4.1 1.3 1 0 0 1 1 1 1 Laminin Domain II AAA_32 PF13654.6 KIY49984.1 - 0.015 14.1 0.4 0.019 13.8 0.4 1.1 1 0 0 1 1 1 0 AAA domain HisKA_3 PF07730.13 KIY49984.1 - 0.017 15.7 3.3 0.68 10.5 0.4 2.9 1 1 2 3 3 3 0 Histidine kinase EzrA PF06160.12 KIY49984.1 - 0.029 12.6 1.8 0.049 11.8 1.7 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA MscS_porin PF12795.7 KIY49984.1 - 0.036 13.6 4.8 0.055 13.0 4.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TMPIT PF07851.13 KIY49984.1 - 0.043 13.1 4.0 0.088 12.0 4.0 1.6 1 1 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 KIY49984.1 - 0.048 13.8 2.8 0.13 12.5 2.6 1.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KIY49984.1 - 0.049 13.7 2.5 0.086 12.9 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cortex-I_coil PF09304.10 KIY49984.1 - 0.05 13.8 2.0 0.095 12.9 0.5 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil Prominin PF05478.11 KIY49984.1 - 0.055 11.4 0.4 0.068 11.1 0.4 1.1 1 0 0 1 1 1 0 Prominin KELK PF15796.5 KIY49984.1 - 0.066 13.7 2.0 11 6.6 0.0 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase IFT57 PF10498.9 KIY49984.1 - 0.086 11.8 3.5 0.11 11.5 3.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RmuC PF02646.16 KIY49984.1 - 0.092 11.9 3.2 5.3 6.1 0.0 2.1 1 1 1 2 2 2 0 RmuC family DUF948 PF06103.11 KIY49984.1 - 0.098 12.9 1.5 7.1 7.0 1.5 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Med30 PF11315.8 KIY49984.1 - 0.099 12.8 1.2 0.34 11.1 1.0 1.8 1 1 0 1 1 1 0 Mediator complex subunit 30 Filament PF00038.21 KIY49984.1 - 0.1 12.2 4.8 0.11 12.0 2.2 1.8 1 1 1 2 2 2 0 Intermediate filament protein Rop-like PF05082.13 KIY49984.1 - 0.11 12.4 5.0 0.21 11.4 0.7 2.9 1 1 2 3 3 3 0 Rop-like KxDL PF10241.9 KIY49984.1 - 0.11 12.8 3.2 8.6 6.7 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein Complex1_51K PF01512.17 KIY49984.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.4 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Spc24 PF08286.11 KIY49984.1 - 0.13 12.5 4.2 2.9 8.2 2.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin PF00261.20 KIY49984.1 - 0.15 11.5 4.1 0.36 10.2 4.1 1.7 1 1 0 1 1 1 0 Tropomyosin Exonuc_VII_L PF02601.15 KIY49984.1 - 0.15 11.6 1.9 0.18 11.3 1.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit T7SS_ESX_EspC PF10824.8 KIY49984.1 - 0.15 12.5 1.3 0.72 10.4 0.3 2.1 1 1 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm LXG PF04740.12 KIY49984.1 - 0.19 11.4 3.6 0.2 11.3 1.4 1.9 1 1 0 1 1 1 0 LXG domain of WXG superfamily FAM76 PF16046.5 KIY49984.1 - 0.23 10.8 1.4 0.31 10.4 1.4 1.1 1 0 0 1 1 1 0 FAM76 protein DUF5339 PF17274.2 KIY49984.1 - 0.35 11.8 6.3 11 6.9 3.1 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5339) TMF_TATA_bd PF12325.8 KIY49984.1 - 0.37 11.0 4.7 2.7 8.2 1.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 KIY49984.1 - 0.42 10.9 5.2 1.2 9.5 5.2 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) H-kinase_dim PF02895.14 KIY49984.1 - 0.46 10.9 2.7 0.51 10.8 0.7 2.0 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain FlaC_arch PF05377.11 KIY49984.1 - 0.69 10.3 2.1 30 5.1 1.1 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HIP1_clath_bdg PF16515.5 KIY49984.1 - 0.75 10.4 6.5 0.96 10.1 0.2 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 KIY49984.1 - 1.5 9.0 5.0 4.1 7.7 1.1 2.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tweety PF04906.13 KIY49984.1 - 4.1 6.0 7.7 2 7.0 0.7 2.1 1 1 1 2 2 2 0 Tweety p450 PF00067.22 KIY49985.1 - 1.4e-52 179.0 0.0 2e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Clr2_transil PF16761.5 KIY49986.1 - 3.5e-21 75.8 0.4 9.3e-21 74.4 0.4 1.8 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KIY49986.1 - 1.3e-13 52.0 0.0 4e-13 50.4 0.0 1.9 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 zf-HIT PF04438.16 KIY49987.1 - 4.4e-07 29.6 14.7 6.4e-07 29.1 14.7 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KIY49987.1 - 0.055 13.6 9.5 0.09 12.9 9.5 1.3 1 0 0 1 1 1 0 MYND finger Tnp_zf-ribbon_2 PF13842.6 KIY49987.1 - 6.3 7.7 14.0 11 7.0 14.0 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon RED_N PF07808.13 KIY49988.1 - 3.5e-17 62.8 2.6 3.5e-17 62.8 2.6 2.6 3 0 0 3 3 3 1 RED-like protein N-terminal region Carb_kinase PF01256.17 KIY49989.1 - 9e-49 166.1 0.0 1.4e-48 165.5 0.0 1.3 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KIY49989.1 - 0.0043 16.5 0.0 0.0099 15.3 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase RNA_pol_Rpb6 PF01192.22 KIY49989.1 - 0.089 12.7 0.7 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb6 Aldo_ket_red PF00248.21 KIY49990.1 - 2.9e-28 98.9 0.4 4.4e-21 75.3 0.2 2.9 1 1 1 2 2 2 2 Aldo/keto reductase family UAA PF08449.11 KIY49992.1 - 9.3e-76 254.9 2.9 1.1e-75 254.7 2.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIY49992.1 - 0.00078 19.6 23.4 0.0051 17.0 7.1 3.3 3 1 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 KIY49992.1 - 0.0015 17.6 0.2 0.0024 16.9 0.2 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KIY49992.1 - 0.0017 17.6 0.1 0.0028 16.9 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 KIY49992.1 - 0.0034 16.7 4.4 0.0087 15.3 0.2 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 KIY49992.1 - 0.035 13.5 3.9 0.84 8.9 0.6 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF4079 PF13301.6 KIY49992.1 - 0.14 12.3 1.9 0.42 10.8 1.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Sdh_cyt PF01127.22 KIY49992.1 - 0.38 10.8 6.8 1.1 9.3 0.3 3.0 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF563 PF04577.14 KIY49993.1 - 6e-19 69.0 0.0 1.2e-18 68.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) RsgA_GTPase PF03193.16 KIY49993.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase zf-MYND PF01753.18 KIY49994.1 - 5.3e-08 32.8 10.7 1.1e-07 31.9 10.7 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY49994.1 - 0.003 17.8 9.2 0.0036 17.6 6.6 2.4 1 1 2 3 3 3 1 zf-MYND-like zinc finger, mRNA-binding NCD3G PF07562.14 KIY49994.1 - 0.45 10.5 3.6 1.3 9.0 0.3 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ecl1 PF12855.7 KIY49994.1 - 1.1 10.4 3.6 0.65 11.1 0.6 1.9 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Mpv17_PMP22 PF04117.12 KIY49995.1 - 1.7e-21 76.2 1.5 3.1e-21 75.3 1.5 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family SnoaL_4 PF13577.6 KIY49996.1 - 9.2e-10 38.7 0.1 1.2e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain Plavaka PF18759.1 KIY49997.1 - 2.8e-31 109.0 0.1 4.4e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase PTP_N PF12453.8 KIY49997.1 - 0.13 12.0 0.6 0.26 11.0 0.6 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal CdiI_2 PF18593.1 KIY49998.1 - 0.66 10.7 3.3 36 5.1 0.1 2.9 3 0 0 3 3 3 0 CdiI immunity protein MFS_1 PF07690.16 KIY49999.1 - 2e-35 122.3 24.5 2e-35 122.3 24.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY49999.1 - 0.0024 16.8 0.0 0.059 12.2 0.0 2.7 1 1 0 1 1 1 1 MFS_1 like family SRP14 PF02290.15 KIY50001.1 - 1.8e-17 63.5 0.9 3.3e-17 62.6 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle 14kD protein DUF1223 PF06764.11 KIY50001.1 - 0.28 11.2 2.7 0.44 10.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) 7TM_GPCR_Srv PF10323.9 KIY50002.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Peptidase_M17 PF00883.21 KIY50004.1 - 2.3e-120 401.6 0.2 3e-120 401.2 0.2 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KIY50004.1 - 3.5e-05 23.7 1.2 9e-05 22.3 1.2 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain bZIP_2 PF07716.15 KIY50005.1 - 4.8e-08 32.9 5.4 7.7e-08 32.3 5.4 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY50005.1 - 2.5e-07 30.7 3.7 3.7e-07 30.1 3.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor Metallophos_2 PF12850.7 KIY50009.1 - 5.4e-06 26.7 0.1 1.2e-05 25.6 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KIY50009.1 - 8.9e-06 26.3 0.8 1.6e-05 25.5 0.8 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CFEM PF05730.11 KIY50010.1 - 1.8e-08 34.3 14.4 2.6e-08 33.8 14.4 1.2 1 0 0 1 1 1 1 CFEM domain Fungal_trans PF04082.18 KIY50011.1 - 2.5e-24 85.7 0.6 2.5e-24 85.7 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY50011.1 - 0.00036 20.6 13.8 0.00062 19.8 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4094 PF13334.6 KIY50011.1 - 0.0065 16.9 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) Striatin PF08232.12 KIY50011.1 - 0.013 16.1 0.7 0.022 15.4 0.7 1.3 1 0 0 1 1 1 0 Striatin family PAP1 PF08601.10 KIY50011.1 - 0.016 15.0 6.4 0.03 14.1 6.4 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 DASH_Hsk3 PF08227.11 KIY50011.1 - 0.19 12.1 1.0 0.51 10.7 1.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like RGCC PF15151.6 KIY50011.1 - 0.21 11.8 5.9 3.2 8.0 4.4 2.4 2 0 0 2 2 2 0 Response gene to complement 32 protein family PRKG1_interact PF15898.5 KIY50011.1 - 0.22 12.4 0.7 0.5 11.3 0.7 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CASP_C PF08172.12 KIY50011.1 - 0.31 10.3 3.3 0.49 9.7 3.3 1.2 1 0 0 1 1 1 0 CASP C terminal RP-C_C PF11800.8 KIY50011.1 - 0.37 10.9 3.1 0.32 11.1 1.3 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region CCDC53 PF10152.9 KIY50011.1 - 0.63 10.5 3.1 1.2 9.5 3.1 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex tRNA-synt_His PF13393.6 KIY50012.1 - 2.2e-40 138.9 0.0 4.7e-36 124.6 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KIY50012.1 - 1.9e-10 40.7 0.1 4.3e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIY50012.1 - 2.1e-05 24.6 0.0 0.00011 22.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 KIY50012.1 - 0.028 14.0 0.0 0.077 12.5 0.0 1.6 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Pkinase PF00069.25 KIY50013.1 - 3.2e-28 98.8 0.0 1.4e-26 93.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50013.1 - 4.8e-08 32.6 0.1 0.00019 20.8 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 KIY50013.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KIY50013.1 - 1.3 7.7 2.7 1 8.1 0.9 1.6 1 1 1 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 KIY50014.1 - 3e-28 98.9 0.0 1.3e-27 96.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50014.1 - 1.3e-08 34.5 2.0 2.2e-06 27.2 0.0 2.7 3 1 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 KIY50014.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DAHP_synth_2 PF01474.16 KIY50015.1 - 2.8e-194 645.7 0.0 3.1e-194 645.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family RPN7 PF10602.9 KIY50016.1 - 4.5e-51 173.0 0.3 6.1e-51 172.6 0.3 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KIY50016.1 - 1.1e-11 45.1 0.1 3.4e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 KIY50016.1 - 0.0063 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_2 PF07719.17 KIY50016.1 - 0.043 13.9 1.3 8 6.9 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_DeoR PF08220.12 KIY50016.1 - 0.086 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Sigma70_r4 PF04545.16 KIY50016.1 - 0.094 12.3 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 RibD_C PF01872.17 KIY50018.1 - 3e-32 112.1 0.1 4.7e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Histone PF00125.24 KIY50019.1 - 1.2e-42 145.4 4.7 7.7e-40 136.3 2.0 2.0 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KIY50019.1 - 0.0043 17.7 2.1 0.0059 17.2 2.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KIY50019.1 - 0.041 14.0 1.2 0.042 14.0 0.1 1.6 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KIY50019.1 - 0.065 13.6 0.2 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 CENP-S protein RPN7 PF10602.9 KIY50020.1 - 4.7e-06 26.4 0.0 1.1e-05 25.2 0.0 1.5 1 1 1 2 2 2 1 26S proteasome subunit RPN7 Pneumo_M2 PF07380.11 KIY50021.1 - 0.097 12.9 0.1 0.1 12.9 0.1 1.0 1 0 0 1 1 1 0 Pneumovirus M2 protein DDE_1 PF03184.19 KIY50022.1 - 0.0007 19.3 0.0 0.00072 19.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KIY50023.1 - 1e-08 35.0 0.0 1.4e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2397 PF09660.10 KIY50024.1 - 0.0046 15.9 0.1 0.0051 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) PKcGMP_CC PF16808.5 KIY50024.1 - 0.0072 16.2 1.0 0.13 12.1 0.1 2.3 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 KIY50024.1 - 0.021 14.8 4.5 0.035 14.1 4.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 KIY50024.1 - 0.059 12.7 0.6 0.067 12.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Dam1 PF08653.10 KIY50024.1 - 0.24 11.2 0.6 1.8 8.4 0.2 2.3 1 1 1 2 2 2 0 DASH complex subunit Dam1 DUF2070 PF09843.9 KIY50025.1 - 1.1 7.5 7.7 1.3 7.2 7.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PIG-S PF10510.9 KIY50025.1 - 1.3 7.7 3.7 1.6 7.5 3.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein LapA_dom PF06305.11 KIY50025.1 - 8.6 6.3 13.1 0.1 12.4 4.5 2.2 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ribosomal_L1 PF00687.21 KIY50026.1 - 4.1e-47 160.6 1.6 4.9e-47 160.3 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pneumo_M2 PF07380.11 KIY50027.1 - 0.097 12.9 0.1 0.1 12.9 0.1 1.0 1 0 0 1 1 1 0 Pneumovirus M2 protein DDE_1 PF03184.19 KIY50028.1 - 0.0007 19.3 0.0 0.00072 19.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KIY50029.1 - 1e-08 35.0 0.0 1.4e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L1 PF00687.21 KIY50031.1 - 5.5e-09 36.0 1.2 3.5e-08 33.4 1.2 2.2 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family RRM_1 PF00076.22 KIY50033.1 - 7.3e-20 70.6 0.0 8.7e-20 70.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY50033.1 - 0.0032 17.1 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY50033.1 - 0.051 13.4 0.0 0.091 12.6 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Lin-8 PF03353.15 KIY50034.1 - 0.59 9.6 2.0 0.93 9.0 2.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GPI-anchored PF10342.9 KIY50035.1 - 1.3e-12 48.3 4.3 1.3e-12 48.3 4.3 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 KIY50037.1 - 5e-11 43.2 1.6 5e-11 43.2 1.6 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RAB3GAP2_C PF14656.6 KIY50037.1 - 0.13 10.5 0.1 0.17 10.1 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Pkinase PF00069.25 KIY50038.1 - 1.5e-27 96.6 0.0 3.4e-22 79.1 0.0 3.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50038.1 - 4.9e-10 39.1 2.4 7.5e-07 28.7 0.0 2.7 3 1 0 3 3 3 2 Protein tyrosine kinase AChE_tetra PF08674.10 KIY50038.1 - 0.5 10.1 2.5 3 7.6 0.1 2.4 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Pkinase PF00069.25 KIY50039.1 - 1.4e-31 109.8 0.0 4.7e-30 104.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50039.1 - 3.7e-10 39.5 0.3 1.1e-06 28.2 0.1 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KIY50040.1 - 5.3e-12 45.6 0.1 2e-09 37.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50040.1 - 1.9e-06 27.4 0.4 9.4e-06 25.1 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Plavaka PF18759.1 KIY50042.1 - 8.8e-93 311.1 0.0 4.2e-68 230.0 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase zf-C2H2 PF00096.26 KIY50042.1 - 0.093 13.2 0.2 0.33 11.5 0.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Nop14 PF04147.12 KIY50042.1 - 8.6 4.4 8.9 13 3.9 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 KIY50044.1 - 0.0002 20.8 0.0 0.00032 20.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Abhydrolase_1 PF00561.20 KIY50048.1 - 6.3e-15 55.5 0.0 1e-14 54.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY50048.1 - 4.2e-13 50.4 3.7 5.4e-13 50.1 3.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY50048.1 - 3.3e-09 36.4 0.0 0.00033 20.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIY50048.1 - 0.00069 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein adh_short PF00106.25 KIY50049.1 - 1.8e-23 83.0 0.4 2.8e-22 79.1 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY50049.1 - 1.6e-12 47.5 1.2 7.2e-08 32.3 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY50049.1 - 0.00013 21.9 0.5 0.00025 21.0 0.2 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY50049.1 - 0.0037 16.7 0.6 0.22 11.0 0.6 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Baculo_PEP_C PF04513.12 KIY50050.1 - 1e-07 32.1 5.1 2.3e-05 24.5 1.3 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KIY50050.1 - 4.6e-07 29.0 0.7 5.7e-07 28.7 0.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 KIY50050.1 - 4.9e-07 29.8 1.9 0.0018 18.3 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) DUF2730 PF10805.8 KIY50050.1 - 4.2e-06 26.8 2.1 0.002 18.2 0.2 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF2730) NPV_P10 PF05531.12 KIY50050.1 - 1.1e-05 25.7 7.3 0.0099 16.3 0.7 3.7 1 1 3 4 4 4 2 Nucleopolyhedrovirus P10 protein DUF1640 PF07798.11 KIY50050.1 - 1.1e-05 25.5 1.4 0.00013 22.1 1.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) LPP PF04728.13 KIY50050.1 - 1.1e-05 25.7 3.9 0.018 15.4 0.2 3.6 1 1 3 4 4 3 3 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 KIY50050.1 - 1.2e-05 25.2 6.3 0.072 13.2 0.3 3.8 1 1 2 3 3 3 2 TolA binding protein trimerisation ADIP PF11559.8 KIY50050.1 - 1.5e-05 25.1 4.6 2e-05 24.7 4.6 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 KIY50050.1 - 2.7e-05 24.4 1.7 0.38 11.0 0.5 2.9 1 1 2 3 3 3 3 Domain of unknown function (DUF5082) DUF812 PF05667.11 KIY50050.1 - 3.7e-05 22.8 0.9 4.3e-05 22.6 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4618 PF15397.6 KIY50050.1 - 3.8e-05 23.3 0.6 0.14 11.5 0.0 2.9 1 1 2 3 3 3 2 Domain of unknown function (DUF4618) SlyX PF04102.12 KIY50050.1 - 5.6e-05 23.7 5.4 0.014 16.0 0.1 3.1 1 1 2 3 3 3 1 SlyX DivIC PF04977.15 KIY50050.1 - 5.9e-05 22.8 3.4 0.081 12.7 0.2 3.0 1 1 2 3 3 3 2 Septum formation initiator DUF2353 PF09789.9 KIY50050.1 - 7.1e-05 22.3 4.4 0.019 14.3 0.1 2.1 1 1 1 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) Atg14 PF10186.9 KIY50050.1 - 0.00012 21.2 0.8 0.00017 20.8 0.8 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Bacillus_HBL PF05791.11 KIY50050.1 - 0.00019 21.3 3.8 0.00047 20.0 0.7 2.1 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) SKA2 PF16740.5 KIY50050.1 - 0.0002 21.1 2.3 0.056 13.2 0.4 2.2 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 PspA_IM30 PF04012.12 KIY50050.1 - 0.00029 20.5 1.3 0.0013 18.4 1.3 1.8 1 1 0 1 1 1 1 PspA/IM30 family TSC22 PF01166.18 KIY50050.1 - 0.00032 20.9 0.1 0.87 9.9 0.0 3.0 1 1 2 3 3 3 1 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 KIY50050.1 - 0.0004 20.4 0.2 0.0027 17.7 0.1 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 KIY50050.1 - 0.00041 20.9 1.8 0.0048 17.5 0.0 2.2 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 CALCOCO1 PF07888.11 KIY50050.1 - 0.00061 18.8 1.1 0.00074 18.5 1.1 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.8 KIY50050.1 - 0.00063 17.4 2.1 0.00076 17.2 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HMMR_C PF15908.5 KIY50050.1 - 0.00081 19.7 0.3 0.016 15.4 0.3 2.4 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal Lzipper-MIP1 PF14389.6 KIY50050.1 - 0.00082 19.6 0.1 0.91 9.9 0.0 3.1 2 1 1 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 COG5 PF10392.9 KIY50050.1 - 0.00084 19.5 0.6 0.037 14.2 0.0 2.0 1 1 1 2 2 2 1 Golgi transport complex subunit 5 TMF_TATA_bd PF12325.8 KIY50050.1 - 0.00085 19.5 2.6 0.048 13.9 0.4 2.4 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 KIY50050.1 - 0.0009 19.6 0.9 0.7 10.3 0.0 3.2 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) Apolipoprotein PF01442.18 KIY50050.1 - 0.00099 19.0 3.2 0.0028 17.5 3.0 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain GAS PF13851.6 KIY50050.1 - 0.0012 18.3 0.4 0.0028 17.1 0.4 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Prominin PF05478.11 KIY50050.1 - 0.0013 16.8 1.8 0.0014 16.7 1.8 1.0 1 0 0 1 1 1 1 Prominin IMD PF08397.11 KIY50050.1 - 0.0015 17.9 1.3 0.0035 16.8 1.3 1.5 1 1 0 1 1 1 1 IRSp53/MIM homology domain EzrA PF06160.12 KIY50050.1 - 0.0016 16.7 0.2 0.0025 16.1 0.2 1.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA HAP1_N PF04849.13 KIY50050.1 - 0.0017 17.6 0.6 0.0084 15.3 0.5 1.9 1 1 0 1 1 1 1 HAP1 N-terminal conserved region DUF4795 PF16043.5 KIY50050.1 - 0.0019 17.9 1.4 0.015 14.9 1.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) WEMBL PF05701.11 KIY50050.1 - 0.0021 16.8 0.5 0.0034 16.2 0.5 1.3 1 1 0 1 1 1 1 Weak chloroplast movement under blue light DUF4407 PF14362.6 KIY50050.1 - 0.0022 17.4 3.9 0.0031 16.9 3.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Syntaxin PF00804.25 KIY50050.1 - 0.0025 17.5 2.5 0.0057 16.3 1.9 1.8 1 1 1 2 2 2 1 Syntaxin ABC_tran_CTD PF16326.5 KIY50050.1 - 0.0025 18.0 0.4 1.2 9.5 0.0 2.9 1 1 3 4 4 4 1 ABC transporter C-terminal domain Filament PF00038.21 KIY50050.1 - 0.0025 17.4 1.4 0.0093 15.6 0.6 1.9 1 1 1 2 2 2 1 Intermediate filament protein KASH_CCD PF14662.6 KIY50050.1 - 0.0031 17.4 0.6 0.0054 16.6 0.6 1.4 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH FH2 PF02181.23 KIY50050.1 - 0.0032 16.6 0.4 0.015 14.4 0.3 1.8 1 1 0 1 1 1 1 Formin Homology 2 Domain GIT_CC PF16559.5 KIY50050.1 - 0.0032 17.3 2.0 2.3 8.1 0.0 3.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CLZ PF16526.5 KIY50050.1 - 0.0037 17.6 4.6 5.1 7.5 0.8 3.1 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 KIY50050.1 - 0.0038 17.4 4.0 0.58 10.3 0.0 2.7 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family DUF713 PF05218.14 KIY50050.1 - 0.0039 17.0 0.2 1.6 8.5 0.0 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF713) LXG PF04740.12 KIY50050.1 - 0.004 16.9 2.0 1.7 8.3 0.1 3.0 1 1 2 3 3 3 1 LXG domain of WXG superfamily ATG16 PF08614.11 KIY50050.1 - 0.0043 17.3 2.1 0.017 15.3 2.1 1.8 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF2383 PF09537.10 KIY50050.1 - 0.0045 17.3 1.0 0.11 12.9 0.1 2.4 1 1 2 3 3 3 1 Domain of unknown function (DUF2383) HsbA PF12296.8 KIY50050.1 - 0.0045 17.4 1.8 0.011 16.1 0.8 2.1 1 1 1 2 2 1 1 Hydrophobic surface binding protein A HMMR_N PF15905.5 KIY50050.1 - 0.0058 16.2 0.6 0.0069 15.9 0.6 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal MAP65_ASE1 PF03999.12 KIY50050.1 - 0.0063 15.3 0.1 0.0081 14.9 0.1 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) AAA_13 PF13166.6 KIY50050.1 - 0.0077 14.9 1.9 0.0098 14.6 1.9 1.2 1 0 0 1 1 1 1 AAA domain Rx_N PF18052.1 KIY50050.1 - 0.0083 16.4 0.8 5.6 7.3 0.2 2.9 1 1 1 2 2 2 0 Rx N-terminal domain Fez1 PF06818.15 KIY50050.1 - 0.0083 16.6 0.5 0.011 16.3 0.5 1.1 1 0 0 1 1 1 1 Fez1 Phage_Mu_Gam PF07352.12 KIY50050.1 - 0.0085 16.0 0.3 0.34 10.8 0.1 2.0 2 0 0 2 2 2 1 Bacteriophage Mu Gam like protein Latarcin PF10279.9 KIY50050.1 - 0.0088 16.4 3.9 2.4 8.6 3.9 2.6 1 1 0 1 1 1 0 Latarcin precursor COG2 PF06148.11 KIY50050.1 - 0.0098 16.0 1.9 0.17 12.0 1.9 2.4 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG7 PF10191.9 KIY50050.1 - 0.011 14.0 1.2 0.14 10.4 0.3 2.0 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) CREPT PF16566.5 KIY50050.1 - 0.013 15.6 0.7 0.44 10.7 0.0 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CCDC154 PF15450.6 KIY50050.1 - 0.015 13.8 3.7 0.09 11.3 2.3 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 154 DUF2746 PF10874.8 KIY50050.1 - 0.015 15.7 1.8 0.23 11.9 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) DUF4201 PF13870.6 KIY50050.1 - 0.016 14.9 0.6 0.097 12.4 0.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Rootletin PF15035.6 KIY50050.1 - 0.017 15.2 2.4 1.4 8.9 0.3 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Golgin_A5 PF09787.9 KIY50050.1 - 0.017 14.6 0.8 0.023 14.2 0.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 KIY50050.1 - 0.017 15.1 0.0 0.11 12.5 0.0 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding F_actin_bind PF08919.10 KIY50050.1 - 0.017 15.2 0.3 0.11 12.6 0.2 2.3 1 1 1 2 2 2 0 F-actin binding AIP3 PF03915.13 KIY50050.1 - 0.018 14.2 3.2 0.026 13.7 3.2 1.3 1 1 0 1 1 1 0 Actin interacting protein 3 Cluap1 PF10234.9 KIY50050.1 - 0.019 14.4 2.3 0.27 10.6 0.9 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 UPF0242 PF06785.11 KIY50050.1 - 0.023 14.8 0.1 0.032 14.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 KIY50050.1 - 0.024 13.9 0.2 0.029 13.6 0.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein CASP_C PF08172.12 KIY50050.1 - 0.026 13.9 1.9 3.3 7.0 0.2 2.3 1 1 0 2 2 2 0 CASP C terminal DUF724 PF05266.14 KIY50050.1 - 0.028 14.2 0.1 0.056 13.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) XhlA PF10779.9 KIY50050.1 - 0.033 14.4 4.0 5.5 7.3 0.3 3.0 1 1 2 3 3 3 0 Haemolysin XhlA DUF4763 PF15960.5 KIY50050.1 - 0.033 13.5 0.4 0.13 11.6 0.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) HrpB7 PF09486.10 KIY50050.1 - 0.034 14.6 4.3 0.34 11.3 4.1 2.1 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) PTRF_SDPR PF15237.6 KIY50050.1 - 0.036 13.7 1.2 0.078 12.6 0.6 1.7 1 1 1 2 2 2 0 PTRF/SDPR family Surfac_D-trimer PF09006.11 KIY50050.1 - 0.037 13.9 0.3 1 9.3 0.0 2.9 2 1 2 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation FUSC PF04632.12 KIY50050.1 - 0.037 12.6 1.3 0.042 12.4 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 KIY50050.1 - 0.051 14.0 0.3 1.4 9.4 0.3 2.5 1 1 0 1 1 1 0 Cell division protein ZapB Remorin_C PF03763.13 KIY50050.1 - 0.052 13.4 1.8 0.16 11.9 0.3 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region Lectin_N PF03954.14 KIY50050.1 - 0.053 13.3 0.8 0.47 10.2 0.2 2.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain YabA PF06156.13 KIY50050.1 - 0.053 14.2 1.7 0.78 10.4 0.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA IFT57 PF10498.9 KIY50050.1 - 0.053 12.5 1.4 0.11 11.5 1.4 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-H PF05837.12 KIY50050.1 - 0.054 13.9 2.3 0.22 12.0 2.3 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF2968 PF11180.8 KIY50050.1 - 0.054 13.1 0.1 0.054 13.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) FAA_hydrolase_N PF09298.11 KIY50050.1 - 0.054 13.7 0.5 0.1 12.8 0.5 1.8 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal kleA_kleC PF17383.2 KIY50050.1 - 0.062 13.6 1.1 2.2 8.7 0.1 2.6 1 1 2 3 3 3 0 Uncharacterized KorC regulated protein A End3 PF12761.7 KIY50050.1 - 0.071 13.3 2.4 3 8.0 0.0 2.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF883 PF05957.13 KIY50050.1 - 0.08 13.5 5.2 0.46 11.1 1.4 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) APG6_N PF17675.1 KIY50050.1 - 0.085 13.4 0.1 0.16 12.5 0.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Cytochrom_B562 PF07361.11 KIY50050.1 - 0.095 13.4 2.0 0.34 11.6 1.3 2.0 1 1 1 2 2 2 0 Cytochrome b562 FAM76 PF16046.5 KIY50050.1 - 0.11 11.9 0.9 0.37 10.1 0.9 1.8 1 1 0 1 1 1 0 FAM76 protein BLOC1_2 PF10046.9 KIY50050.1 - 0.11 12.8 2.6 0.55 10.6 0.2 2.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF148 PF02520.17 KIY50050.1 - 0.11 12.6 4.6 1.5 9.0 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 Phasin PF05597.11 KIY50050.1 - 0.15 12.1 2.7 12 5.9 0.5 2.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SseC PF04888.12 KIY50050.1 - 0.19 11.3 3.4 0.32 10.5 0.3 2.0 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family DUF3573 PF12097.8 KIY50050.1 - 0.23 10.3 2.8 3.5 6.4 2.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF948 PF06103.11 KIY50050.1 - 0.46 10.8 4.4 3.9 7.8 4.4 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PhrC_PhrF PF11131.8 KIY50051.1 - 0.045 13.3 1.4 4.8 6.8 0.7 2.4 2 0 0 2 2 2 0 Rap-phr extracellular signalling CTK3 PF12243.8 KIY50054.1 - 1.7e-34 118.5 0.0 3.1e-34 117.6 0.0 1.4 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KIY50054.1 - 4.2e-24 84.5 2.3 7.6e-24 83.7 2.3 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Chs7 PF12271.8 KIY50055.1 - 3.9e-113 377.6 25.6 4.5e-113 377.4 25.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF5127 PF17168.4 KIY50056.1 - 6.2e-70 235.5 4.0 9e-70 235.0 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIY50056.1 - 5.4e-50 169.4 0.6 1.3e-49 168.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIY50056.1 - 1.8e-15 57.8 0.4 1.8e-15 57.8 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIY50056.1 - 3.1e-05 23.4 0.1 9.7e-05 21.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Cyclin PF08613.11 KIY50058.1 - 3.9e-11 43.6 0.0 1e-10 42.2 0.0 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KIY50058.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain G-alpha PF00503.20 KIY50059.1 - 4.7e-96 322.0 0.2 5.9e-96 321.7 0.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY50059.1 - 3.7e-11 42.8 3.6 1.8e-07 30.8 0.7 2.7 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY50059.1 - 0.0013 18.1 5.1 0.019 14.3 0.4 2.6 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY50059.1 - 0.0084 15.7 0.1 4.2 6.9 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY50059.1 - 0.014 15.4 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 KIY50059.1 - 0.024 14.9 0.6 2 8.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KIY50059.1 - 0.09 11.9 0.1 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 KIY50059.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ChaC PF04752.12 KIY50060.1 - 1.5e-46 158.7 0.0 1.8e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein DUF5127 PF17168.4 KIY50061.1 - 2.4e-68 230.3 7.7 3.7e-68 229.7 7.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIY50061.1 - 1.7e-50 171.0 1.0 3.3e-50 170.1 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIY50061.1 - 1.4e-16 61.4 0.4 4.2e-16 59.8 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIY50061.1 - 0.00017 21.1 0.1 0.00051 19.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Pkinase PF00069.25 KIY50062.1 - 1.5e-05 24.5 0.1 2.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50062.1 - 4e-05 23.0 0.0 6.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY50062.1 - 0.0039 16.6 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PhoU_div PF01865.16 KIY50065.1 - 0.24 10.7 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 AAA PF00004.29 KIY50066.1 - 3.3e-39 134.3 0.0 2e-11 44.4 0.0 5.3 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KIY50066.1 - 4.9e-35 121.0 0.0 9.6e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY50066.1 - 1.8e-24 87.0 26.1 3.4e-22 79.5 0.0 6.9 6 1 0 6 6 5 2 AAA domain AAA_30 PF13604.6 KIY50066.1 - 1.4e-18 67.3 8.7 6e-05 22.8 0.0 6.0 6 0 0 6 6 5 5 AAA domain AAA_lid_6 PF17866.1 KIY50066.1 - 6.6e-17 61.5 6.1 5.6e-09 36.1 0.4 3.9 3 0 0 3 3 3 2 AAA lid domain AAA_19 PF13245.6 KIY50066.1 - 8.1e-17 61.9 0.0 3.5e-08 33.9 0.0 5.4 4 2 1 5 5 4 2 AAA domain AAA_5 PF07728.14 KIY50066.1 - 8.7e-14 51.7 1.2 0.0032 17.5 0.0 5.1 5 0 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY50066.1 - 2.7e-11 43.9 7.5 0.15 12.3 0.0 7.5 5 3 0 5 5 4 3 AAA domain Viral_helicase1 PF01443.18 KIY50066.1 - 3e-09 37.0 0.1 0.16 11.7 0.0 5.7 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KIY50066.1 - 3.1e-09 36.5 0.1 0.31 10.4 0.0 4.7 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KIY50066.1 - 2e-07 30.9 0.0 1.2 8.9 0.0 4.8 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KIY50066.1 - 4.8e-07 29.7 0.1 0.98 9.1 0.0 4.5 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KIY50066.1 - 5.6e-07 29.9 0.0 5.1 7.5 0.0 4.7 4 0 0 4 4 4 0 RNA helicase AAA_18 PF13238.6 KIY50066.1 - 1.7e-06 28.6 2.7 5.5 7.5 0.0 5.2 4 0 0 4 4 4 0 AAA domain ResIII PF04851.15 KIY50066.1 - 3.1e-06 27.3 3.8 0.0027 17.7 0.0 5.2 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KIY50066.1 - 3.3e-06 26.9 0.2 8 6.1 0.0 5.5 5 1 0 5 5 5 0 Sigma-54 interaction domain DUF2075 PF09848.9 KIY50066.1 - 1e-05 25.0 1.6 0.02 14.1 0.0 5.3 5 1 1 6 6 6 1 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 KIY50066.1 - 1.7e-05 24.9 0.0 3.1 7.9 0.0 4.5 4 0 0 4 4 4 1 Torsin AAA_33 PF13671.6 KIY50066.1 - 2e-05 24.8 8.5 0.77 9.9 0.0 5.6 5 0 0 5 5 4 1 AAA domain AAA_24 PF13479.6 KIY50066.1 - 8.6e-05 22.4 4.6 1.5 8.5 0.1 5.0 5 0 0 5 5 5 1 AAA domain AAA_7 PF12775.7 KIY50066.1 - 0.00051 19.6 1.3 7.7 6.0 0.0 4.3 4 0 0 4 4 4 0 P-loop containing dynein motor region PhoH PF02562.16 KIY50066.1 - 0.0016 18.0 3.8 1 8.8 0.0 4.9 5 0 0 5 5 5 1 PhoH-like protein ATPase PF06745.13 KIY50066.1 - 0.0046 16.3 1.1 0.74 9.1 0.0 3.9 4 0 0 4 4 4 1 KaiC SRP54 PF00448.22 KIY50066.1 - 0.0051 16.5 1.3 2.2 7.9 0.1 4.1 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KIY50066.1 - 0.0085 16.3 15.1 0.5 10.6 0.0 5.9 6 0 0 6 6 4 1 AAA domain DEAD PF00270.29 KIY50066.1 - 0.016 15.0 0.0 0.21 11.3 0.0 3.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 KIY50066.1 - 0.041 13.0 1.6 4 6.4 0.1 3.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_16 PF13191.6 KIY50066.1 - 0.064 13.6 27.1 1.6 9.1 0.0 6.6 8 0 0 8 8 4 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIY50066.1 - 0.11 12.3 0.4 8.1 6.3 0.0 3.5 4 0 0 4 4 3 0 RsgA GTPase PRK PF00485.18 KIY50066.1 - 0.12 12.1 0.6 20 4.9 0.0 4.0 3 1 1 4 4 4 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 KIY50066.1 - 0.15 11.6 5.2 7.4 6.1 0.1 4.7 4 1 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 KIY50066.1 - 0.16 11.9 1.2 31 4.4 0.0 3.7 4 0 0 4 4 4 0 NTPase CbiA PF01656.23 KIY50066.1 - 0.16 12.0 1.3 26 4.9 0.0 4.1 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 KIY50066.1 - 0.32 11.5 9.9 32 5.0 0.0 5.5 5 1 1 6 6 5 0 ABC transporter Helicase_RecD PF05127.14 KIY50066.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.2 3 0 0 3 3 2 0 Helicase Cob_adeno_trans PF01923.18 KIY50066.1 - 5.5 7.1 10.0 0.056 13.6 0.7 2.4 2 1 0 2 2 1 0 Cobalamin adenosyltransferase ERCC4 PF02732.15 KIY50070.1 - 1.8e-19 70.5 0.0 3.9e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain MOZ_SAS PF01853.18 KIY50071.1 - 1.7e-55 187.4 0.0 5.6e-54 182.5 0.0 2.2 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 KIY50071.1 - 1e-13 50.6 3.1 1.9e-07 30.6 0.3 2.9 3 0 0 3 3 3 2 MYST family zinc finger domain Tudor-knot PF11717.8 KIY50071.1 - 2e-08 34.0 0.1 4.6e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KIY50071.1 - 0.016 15.6 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-LYAR PF08790.11 KIY50071.1 - 0.041 13.8 0.3 0.11 12.4 0.3 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Ribosomal_L19e PF01280.20 KIY50072.1 - 2.3e-60 202.8 12.0 2.3e-60 202.8 12.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e PIEZO PF15917.5 KIY50072.1 - 6.6 6.1 9.9 2.8 7.4 7.8 1.5 1 1 0 1 1 1 0 Piezo Laminin_I PF06008.14 KIY50073.1 - 0.0068 16.1 1.7 0.0078 16.0 1.7 1.3 1 1 0 1 1 1 1 Laminin Domain I Filament PF00038.21 KIY50073.1 - 0.07 12.7 7.2 0.15 11.6 7.2 1.6 1 1 0 1 1 1 0 Intermediate filament protein Spc29 PF17082.5 KIY50073.1 - 0.079 12.8 4.1 0.14 11.9 4.0 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 Mu-like_Pro PF10123.9 KIY50073.1 - 0.12 12.0 2.0 0.14 11.7 2.0 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein DASH_Spc34 PF08657.10 KIY50073.1 - 0.16 11.8 4.9 0.21 11.4 1.4 2.1 1 1 2 3 3 3 0 DASH complex subunit Spc34 DUF4407 PF14362.6 KIY50073.1 - 0.3 10.4 3.3 0.74 9.1 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-U1 PF06220.12 KIY50073.1 - 0.31 10.9 1.9 0.58 10.0 1.9 1.4 1 0 0 1 1 1 0 U1 zinc finger KfrA_N PF11740.8 KIY50073.1 - 4.2 8.1 9.4 2.3 8.9 1.1 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term SlyX PF04102.12 KIY50073.1 - 7.6 7.2 7.9 4.5 8.0 0.9 3.3 2 1 1 3 3 3 0 SlyX MFS_1 PF07690.16 KIY50074.1 - 1.7e-28 99.6 21.6 1.7e-28 99.6 21.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY50074.1 - 0.00027 19.9 0.7 0.00027 19.9 0.7 1.8 2 1 0 2 2 2 1 MFS_1 like family Sec62 PF03839.16 KIY50074.1 - 0.66 9.4 4.9 1.2 8.6 4.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Hydantoinase_B PF02538.14 KIY50075.1 - 4.7e-179 596.1 0.6 6.4e-179 595.6 0.6 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KIY50075.1 - 1.7e-96 322.9 0.7 6.6e-96 321.0 0.3 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIY50075.1 - 2.2e-52 177.4 0.2 1.2e-50 171.7 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Ski2_N PF17911.1 KIY50075.1 - 0.00054 19.8 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region Actin PF00022.19 KIY50076.1 - 5.6e-147 489.6 0.0 2.7e-146 487.4 0.0 1.8 1 1 0 1 1 1 1 Actin Peptidase_M61 PF05299.12 KIY50077.1 - 0.15 12.5 0.4 0.22 11.9 0.4 1.2 1 0 0 1 1 1 0 M61 glycyl aminopeptidase Miga PF10265.9 KIY50077.1 - 0.28 10.1 0.0 0.32 9.9 0.0 1.0 1 0 0 1 1 1 0 Mitoguardin DAO PF01266.24 KIY50078.1 - 1.7e-27 96.9 0.2 3.3e-26 92.7 0.2 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY50078.1 - 0.031 14.5 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY50078.1 - 0.039 13.9 0.0 0.09 12.8 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KIY50078.1 - 0.22 11.8 0.0 0.38 11.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Protoglobin PF11563.8 KIY50079.1 - 1.1e-33 116.4 0.0 1.2e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Protoglobin adh_short PF00106.25 KIY50080.1 - 0.00017 21.1 0.1 0.00023 20.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY50080.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Rib PF08428.10 KIY50082.1 - 0.1 12.6 0.9 1.9 8.5 0.1 2.8 2 1 1 3 3 3 0 Rib/alpha-like repeat Cir_N PF10197.9 KIY50083.1 - 6.5e-06 26.2 0.3 6.5e-06 26.2 0.3 2.1 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Redoxin PF08534.10 KIY50085.1 - 1.5e-36 125.3 0.0 1.7e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIY50085.1 - 1.7e-11 44.1 0.0 1.9e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF3552 PF12072.8 KIY50087.1 - 0.0023 17.4 3.3 0.0049 16.3 3.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Fez1 PF06818.15 KIY50087.1 - 0.0049 17.3 0.8 0.011 16.2 0.8 1.6 1 0 0 1 1 1 1 Fez1 FAM76 PF16046.5 KIY50087.1 - 0.65 9.3 4.4 0.22 10.9 1.0 1.9 2 0 0 2 2 2 0 FAM76 protein Spc7 PF08317.11 KIY50087.1 - 2.1 7.2 6.1 3.5 6.4 6.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Ndc1_Nup PF09531.10 KIY50087.1 - 2.3 6.8 3.8 3.2 6.3 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SHD1 PF03983.12 KIY50088.1 - 1.3e-28 98.6 0.0 3.4e-28 97.3 0.0 1.8 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 KIY50088.1 - 1.6e-27 94.9 4.0 2.5e-11 43.0 0.1 3.6 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 KIY50088.1 - 2.2e-24 85.1 16.1 2.7e-10 39.9 0.2 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KIY50088.1 - 2.4e-14 52.8 0.1 6.6e-05 22.5 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 KIY50088.1 - 0.28 11.5 4.4 10 6.5 0.3 3.5 3 0 0 3 3 3 0 Bacterial SH3 domain U79_P34 PF03064.16 KIY50088.1 - 0.41 10.0 6.4 0.76 9.1 6.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.8 KIY50088.1 - 0.92 8.3 6.1 1.3 7.8 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glyco_hydro_92 PF07971.12 KIY50090.1 - 2.9e-14 52.8 0.0 4.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIY50090.1 - 6.4e-13 49.2 0.0 8.7e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain HTH_35 PF13693.6 KIY50091.1 - 0.046 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PPR_3 PF13812.6 KIY50091.1 - 0.16 12.1 0.0 0.5 10.5 0.0 1.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain HTH_21 PF13276.6 KIY50091.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain Exonuc_VII_L PF02601.15 KIY50092.1 - 0.49 9.9 5.3 0.12 11.9 1.9 1.6 1 1 1 2 2 2 0 Exonuclease VII, large subunit SlyX PF04102.12 KIY50092.1 - 4.4 8.0 10.9 4 8.1 2.1 3.4 2 1 1 3 3 3 0 SlyX Sugar_tr PF00083.24 KIY50093.1 - 0.00014 20.9 1.7 0.00014 20.9 1.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY50093.1 - 0.087 11.7 2.0 0.087 11.7 2.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DDE_1 PF03184.19 KIY50094.1 - 3.6e-12 46.3 0.0 7e-12 45.3 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.14 KIY50095.1 - 4.5e-10 39.2 0.0 8.7e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region p450 PF00067.22 KIY50096.1 - 1.9e-24 86.3 0.2 6.2e-24 84.6 0.2 1.6 1 1 0 1 1 1 1 Cytochrome P450 SYS1 PF09801.9 KIY50101.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network DUF4653 PF15546.6 KIY50101.1 - 0.63 9.6 6.6 0.076 12.6 2.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) Retrotran_gag_2 PF14223.6 KIY50102.1 - 3.9e-12 46.0 0.4 3.4e-09 36.5 0.1 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIY50102.1 - 0.0069 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DNA_processg_A PF02481.15 KIY50102.1 - 0.053 12.8 0.4 0.083 12.1 0.4 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A CRAM_rpt PF07016.11 KIY50102.1 - 5.7 6.9 5.7 2.8 7.8 2.1 2.2 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor zf-CCHC_2 PF13696.6 KIY50105.1 - 0.37 10.7 6.9 0.78 9.6 6.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Arnt_C PF18583.1 KIY50106.1 - 0.023 14.3 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Aminoarabinose transferase C-terminal domain RVT_thumb PF06817.14 KIY50106.1 - 0.1 12.4 0.5 0.65 9.9 0.1 2.3 1 1 1 2 2 2 0 Reverse transcriptase thumb domain Helicase_C PF00271.31 KIY50109.1 - 1.5e-08 35.0 0.1 4.5e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pkinase PF00069.25 KIY50110.1 - 3.8e-52 177.3 0.0 6.8e-52 176.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50110.1 - 7e-23 81.2 0.0 1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIY50110.1 - 0.0012 18.5 0.2 0.003 17.2 0.1 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KIY50110.1 - 0.002 18.1 0.1 0.002 18.1 0.1 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY50110.1 - 0.043 13.4 0.4 0.1 12.2 0.4 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase TFIIA PF03153.13 KIY50110.1 - 4.6 7.1 22.9 6.6 6.6 22.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ecm29 PF13001.7 KIY50113.1 - 0.014 14.1 0.2 0.017 13.8 0.2 1.1 1 0 0 1 1 1 0 Proteasome stabiliser YwqJ-deaminase PF14431.6 KIY50113.1 - 0.078 13.2 0.2 0.2 11.8 0.2 1.8 1 0 0 1 1 1 0 YwqJ-like deaminase Clr5 PF14420.6 KIY50115.1 - 0.076 13.3 0.2 0.27 11.5 0.2 1.9 1 0 0 1 1 1 0 Clr5 domain Retrotran_gag_2 PF14223.6 KIY50116.1 - 4.6e-12 45.8 0.0 1e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIY50116.1 - 0.019 14.8 0.0 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIY50116.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) LdpA_C PF12617.8 KIY50116.1 - 0.07 12.7 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal NDC10_II PF16787.5 KIY50121.1 - 0.024 13.7 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Phage_integrase PF00589.22 KIY50121.1 - 0.15 11.9 0.0 0.94 9.2 0.0 2.0 1 1 0 1 1 1 0 Phage integrase family UDPGP PF01704.18 KIY50123.1 - 1e-195 650.2 1.0 1.2e-195 650.0 1.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_S8e PF01201.22 KIY50124.1 - 1.3e-55 187.4 0.7 1.8e-55 186.9 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Sugar_tr PF00083.24 KIY50126.1 - 1e-96 324.6 15.8 1.2e-96 324.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY50126.1 - 9.9e-21 74.0 42.0 1.1e-14 54.2 11.1 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIY50126.1 - 0.00061 18.2 1.0 0.00061 18.2 1.0 2.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family F-box-like PF12937.7 KIY50127.1 - 0.0005 19.9 5.4 0.0083 16.0 3.3 3.2 2 1 0 2 2 2 1 F-box-like Ribosomal_S30 PF04758.14 KIY50128.1 - 1.4e-28 98.8 7.8 2.2e-28 98.2 7.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 LSM PF01423.22 KIY50128.1 - 5.4e-11 42.0 0.1 1.2e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY50128.1 - 0.12 12.5 0.3 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 Ataxin 2 SM domain WD40 PF00400.32 KIY50129.1 - 4.6e-25 87.4 9.7 1.2e-06 29.1 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY50129.1 - 3.2e-06 27.3 0.1 0.74 10.1 0.0 4.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY50129.1 - 0.00085 18.7 0.0 0.047 13.0 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain DUF5046 PF16465.5 KIY50129.1 - 0.00087 18.8 1.0 0.63 9.4 0.1 2.8 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) PQQ PF01011.21 KIY50129.1 - 0.0098 15.8 0.1 9.4 6.4 0.0 2.8 2 0 0 2 2 2 2 PQQ enzyme repeat F-box-like PF12937.7 KIY50130.1 - 8.1e-08 32.0 2.3 2.4e-07 30.5 2.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY50130.1 - 1.8e-05 24.5 0.4 4.9e-05 23.1 0.4 1.8 1 0 0 1 1 1 1 F-box domain Sugar_tr PF00083.24 KIY50131.1 - 4e-96 322.6 17.8 4.5e-96 322.4 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY50131.1 - 9.7e-26 90.5 57.9 6.1e-24 84.6 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIY50131.1 - 5.7e-05 21.6 1.0 5.7e-05 21.6 1.0 2.2 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF1129 PF06570.11 KIY50131.1 - 8.2 5.9 7.2 19 4.7 7.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Ribosomal_S7 PF00177.21 KIY50132.1 - 3.8e-36 124.0 1.8 4.6e-36 123.7 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ten1 PF12658.7 KIY50134.1 - 0.0025 17.8 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 2 Telomere capping, CST complex subunit Ten1_2 PF15490.6 KIY50134.1 - 0.0084 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit UDPGP PF01704.18 KIY50135.1 - 3.2e-197 655.2 1.2 3.6e-197 655.0 1.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Smoothelin PF12510.8 KIY50135.1 - 0.084 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein AA_permease_2 PF13520.6 KIY50136.1 - 1.7e-65 221.5 49.8 2e-65 221.3 49.8 1.0 1 0 0 1 1 1 1 Amino acid permease Macoilin PF09726.9 KIY50137.1 - 7.7e-06 24.8 6.4 9.1e-06 24.5 6.4 1.1 1 0 0 1 1 1 1 Macoilin family DUF737 PF05300.11 KIY50137.1 - 0.0048 17.3 4.6 0.0057 17.0 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) DUF4407 PF14362.6 KIY50137.1 - 0.12 11.7 5.4 0.17 11.2 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) 5_nucleotid PF05761.14 KIY50137.1 - 2.6 6.9 4.4 3.6 6.4 4.4 1.2 1 0 0 1 1 1 0 5' nucleotidase family Zea_mays_MuDR PF05928.11 KIY50139.1 - 0.44 10.1 2.6 0.54 9.9 2.6 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) SNF2_N PF00176.23 KIY50140.1 - 1.1e-55 188.8 0.0 1.6e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KIY50140.1 - 2.4e-18 65.8 0.0 5.9e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.18 KIY50140.1 - 8.1e-12 45.8 0.0 2.6e-11 44.2 0.0 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_2 PF13923.6 KIY50140.1 - 2.3e-08 33.7 7.3 6.4e-08 32.3 7.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KIY50140.1 - 5.8e-08 33.1 0.0 0.0015 18.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KIY50140.1 - 6.4e-08 32.3 5.9 1.5e-07 31.2 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KIY50140.1 - 8.3e-08 32.4 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KIY50140.1 - 1.1e-05 25.2 8.1 2.1e-05 24.3 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY50140.1 - 4.3e-05 23.8 7.1 0.0001 22.5 7.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIY50140.1 - 5.2e-05 23.1 6.6 0.0001 22.1 6.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY50140.1 - 9.1e-05 22.4 10.5 0.00023 21.1 10.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger SWI2_SNF2 PF18766.1 KIY50140.1 - 0.00019 21.2 0.2 0.0026 17.5 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase zf-C3HC4_4 PF15227.6 KIY50140.1 - 0.00031 20.8 8.5 0.00069 19.7 8.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIY50140.1 - 0.00047 20.0 4.9 0.001 18.9 4.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KIY50140.1 - 0.014 15.7 5.8 0.043 14.1 5.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain ERCC3_RAD25_C PF16203.5 KIY50140.1 - 0.095 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_6 PF14835.6 KIY50140.1 - 0.11 12.4 3.1 0.27 11.2 3.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Cue1_U7BR PF18499.1 KIY50140.1 - 0.12 12.5 0.0 22 5.2 0.0 2.7 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 YL1 PF05764.13 KIY50140.1 - 4.9 7.2 6.9 0.44 10.6 1.6 1.9 2 0 0 2 2 2 0 YL1 nuclear protein Nse4_C PF08743.10 KIY50141.1 - 9.5e-34 115.5 0.8 3.6e-33 113.7 0.1 2.1 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KIY50141.1 - 1.3e-20 73.3 0.8 2.9e-20 72.1 0.8 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE ARPC4 PF05856.12 KIY50142.1 - 1.9e-80 268.3 5.3 2.2e-80 268.1 5.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FKBP_C PF00254.28 KIY50143.1 - 1.4e-28 99.0 0.0 3.4e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KIY50143.1 - 3.9e-21 75.6 1.0 3.3e-20 72.6 0.0 2.2 2 0 0 2 2 2 1 Nucleoplasmin-like domain TAF4 PF05236.14 KIY50143.1 - 0.00026 20.8 3.8 0.0003 20.7 3.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family RNA_pol_Rpc4 PF05132.14 KIY50143.1 - 0.025 15.0 6.0 0.095 13.1 6.3 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ycf1 PF05758.12 KIY50143.1 - 0.63 7.8 2.9 0.86 7.4 2.9 1.2 1 0 0 1 1 1 0 Ycf1 Presenilin PF01080.17 KIY50143.1 - 1.7 7.4 4.5 2.2 6.9 4.5 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 KIY50143.1 - 2.9 6.6 5.5 3.3 6.4 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Coilin_N PF15862.5 KIY50143.1 - 3 7.6 13.0 6.5 6.6 13.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus EFTUD2 PF16004.5 KIY50143.1 - 9.6 6.8 17.8 25 5.5 0.1 3.1 2 1 1 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Zip PF02535.22 KIY50143.1 - 9.6 5.3 5.7 15 4.7 5.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.6 KIY50143.1 - 9.8 5.7 8.9 15 5.1 8.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RHD3 PF05879.12 KIY50144.1 - 1.3e-244 813.8 0.3 2.6e-244 812.8 0.3 1.4 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 KIY50144.1 - 1.6e-06 28.1 0.0 4.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIY50144.1 - 2.3e-05 24.5 0.0 4.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GBP PF02263.19 KIY50144.1 - 5e-05 22.7 0.1 9.2e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 KIY50144.1 - 0.00094 19.5 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 KIY50144.1 - 0.065 12.5 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 KIY50144.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B SET PF00856.28 KIY50145.1 - 2.1e-13 51.0 0.2 5.8e-12 46.3 0.2 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KIY50145.1 - 0.11 13.2 0.0 0.96 10.1 0.0 2.1 2 0 0 2 2 2 0 SAF domain UvdE PF03851.14 KIY50147.1 - 1.6e-86 290.0 0.0 1.9e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF4037 PF13228.6 KIY50147.1 - 0.17 12.7 0.0 0.45 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) adh_short_C2 PF13561.6 KIY50148.1 - 3.2e-54 183.9 0.4 3.9e-54 183.7 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY50148.1 - 2.3e-39 134.9 0.1 2.9e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY50148.1 - 1e-08 35.3 0.6 1.1e-07 32.0 0.6 2.1 1 1 0 1 1 1 1 KR domain Cpn60_TCP1 PF00118.24 KIY50149.1 - 9.8e-165 548.9 0.9 1.2e-164 548.6 0.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIIA PF03153.13 KIY50150.1 - 5e-43 148.7 17.3 1.4e-24 87.8 16.1 2.7 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Coatomer_WDAD PF04053.14 KIY50151.1 - 7.3e-151 503.2 0.0 1.7e-150 501.9 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KIY50151.1 - 4.3e-38 128.6 3.7 1.6e-07 31.9 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY50151.1 - 2.4e-08 34.2 0.0 0.015 15.6 0.0 6.2 5 3 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain MetallophosC PF16370.5 KIY50151.1 - 0.061 13.6 0.1 0.27 11.5 0.0 2.1 1 1 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase LigD_N PF13298.6 KIY50151.1 - 0.082 13.2 0.4 4.2 7.7 0.0 3.1 3 0 0 3 3 3 0 DNA polymerase Ligase (LigD) WD40_like PF17005.5 KIY50151.1 - 0.14 11.5 0.1 38 3.5 0.0 3.0 3 0 0 3 3 3 0 WD40-like domain Glyco_transf_90 PF05686.12 KIY50152.1 - 2.6e-18 66.1 0.1 6.3e-16 58.3 0.0 2.5 3 0 0 3 3 3 2 Glycosyl transferase family 90 bZIP_2 PF07716.15 KIY50153.1 - 3.1e-10 40.0 12.8 4.6e-10 39.4 12.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY50153.1 - 4.4e-05 23.5 8.0 8.6e-05 22.6 8.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KIY50153.1 - 0.029 14.9 4.2 0.053 14.0 4.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.18 KIY50153.1 - 0.062 13.6 1.1 0.11 12.8 1.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family zf-CCCH PF00642.24 KIY50154.1 - 2.1e-09 37.0 2.7 4.7e-09 35.9 2.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KIY50154.1 - 6.1e-08 32.4 5.2 1.1e-07 31.6 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY50154.1 - 8.5e-07 28.8 7.4 1.5e-06 28.1 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY50154.1 - 5.5e-06 26.3 8.7 1.1e-05 25.4 8.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY50154.1 - 6.8e-06 25.8 7.4 1.3e-05 24.9 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KIY50154.1 - 1.5e-05 24.8 4.4 2.9e-05 23.9 4.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KIY50154.1 - 4.4e-05 23.2 8.1 9e-05 22.3 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KIY50154.1 - 0.00016 21.7 2.8 0.00016 21.7 2.8 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KIY50154.1 - 0.00021 21.5 7.2 0.00041 20.6 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KIY50154.1 - 0.0016 18.2 2.9 0.003 17.3 2.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 KIY50154.1 - 0.0048 17.0 6.9 0.012 15.7 6.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIY50154.1 - 0.015 15.2 6.4 0.028 14.3 6.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-H2C2_2 PF13465.6 KIY50156.1 - 0.27 11.7 0.3 0.27 11.7 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KIY50156.1 - 1.6 9.4 7.7 0.37 11.3 2.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Metallophos PF00149.28 KIY50157.1 - 5.3e-36 125.0 0.1 6.9e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY50157.1 - 0.039 14.4 0.8 0.085 13.3 0.8 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain CRAL_TRIO PF00650.20 KIY50158.1 - 5e-11 42.6 0.0 9.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain OPT PF03169.15 KIY50159.1 - 1.1e-156 523.1 56.1 1.3e-151 506.3 49.1 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein DUF3093 PF11292.8 KIY50159.1 - 0.19 12.0 1.7 0.69 10.2 1.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3093) LIM PF00412.22 KIY50160.1 - 3.9e-28 97.5 21.1 1.9e-13 50.4 2.9 3.4 3 0 0 3 3 3 3 LIM domain zf-C3HC4_2 PF13923.6 KIY50160.1 - 1.6 8.7 8.1 18 5.2 0.0 3.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Radial_spoke PF04712.12 KIY50160.1 - 3.8 6.3 5.7 6 5.7 5.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DUF2321 PF10083.9 KIY50160.1 - 6.2 6.4 8.2 0.54 9.9 1.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) PI3K_p85B PF02192.16 KIY50161.1 - 0.069 12.9 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain Inhibitor_I9 PF05922.16 KIY50162.1 - 0.00084 20.0 0.0 0.0024 18.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 LysM PF01476.20 KIY50163.1 - 8.8e-08 32.1 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 LysM domain Asparaginase_2 PF01112.18 KIY50164.1 - 1.2e-79 267.5 0.2 9.1e-60 202.2 0.0 2.1 2 0 0 2 2 2 2 Asparaginase STE3 PF02076.15 KIY50165.1 - 5.8e-45 153.7 8.9 9e-45 153.1 8.9 1.3 1 0 0 1 1 1 1 Pheromone A receptor Gag_spuma PF03276.14 KIY50165.1 - 0.45 8.9 1.0 0.59 8.5 1.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein PTH2 PF01981.16 KIY50166.1 - 3.4e-13 49.9 0.3 5e-13 49.4 0.0 1.4 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 Pyr_redox_2 PF07992.14 KIY50167.1 - 5.1e-31 108.0 0.0 6.5e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY50167.1 - 7.4e-13 48.9 0.0 1.3e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY50167.1 - 0.00016 21.7 0.2 0.48 10.4 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIY50167.1 - 0.0027 17.0 0.3 0.012 14.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY50167.1 - 0.12 12.6 0.1 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KIY50167.1 - 0.14 12.7 0.4 1.9 9.0 0.0 2.7 3 1 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KIY50167.1 - 0.16 10.8 0.3 14 4.4 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase Abhydrolase_3 PF07859.13 KIY50167.1 - 0.18 11.6 0.0 1 9.2 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lycopene_cycl PF05834.12 KIY50167.1 - 0.19 10.7 0.4 8.4 5.3 0.0 3.0 2 2 2 4 4 4 0 Lycopene cyclase protein DAO PF01266.24 KIY50167.1 - 1.8 8.0 6.0 36 3.8 0.0 3.5 2 2 2 4 4 4 0 FAD dependent oxidoreductase Pex24p PF06398.11 KIY50168.1 - 1.1e-29 103.6 10.3 1.3e-27 96.8 10.3 2.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Mannosyl_trans2 PF04188.13 KIY50169.1 - 5.5e-46 157.8 26.3 7e-46 157.4 26.3 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Phasin PF05597.11 KIY50170.1 - 0.0031 17.5 0.7 0.0069 16.4 0.7 1.5 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) CENP-K PF11802.8 KIY50170.1 - 0.031 13.9 0.8 0.049 13.2 0.8 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF4201 PF13870.6 KIY50170.1 - 0.2 11.4 3.2 0.31 10.7 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) XhlA PF10779.9 KIY50170.1 - 0.59 10.4 3.7 0.29 11.4 0.7 2.0 2 0 0 2 2 2 0 Haemolysin XhlA ADIP PF11559.8 KIY50170.1 - 0.86 9.7 5.0 1.6 8.8 5.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3365 PF11845.8 KIY50170.1 - 1.6 9.1 4.7 1.3 9.3 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) FlxA PF14282.6 KIY50170.1 - 9.1 6.3 8.1 0.36 10.8 2.0 1.8 2 0 0 2 2 2 0 FlxA-like protein Gti1_Pac2 PF09729.9 KIY50171.1 - 1.3e-21 77.5 1.4 5.7e-18 65.6 0.2 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family DSPc PF00782.20 KIY50173.1 - 2.5e-06 27.3 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KIY50173.1 - 0.0002 21.1 0.1 0.00027 20.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KIY50173.1 - 0.0084 15.7 0.9 0.087 12.4 0.1 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIY50173.1 - 0.016 15.4 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KIY50173.1 - 0.21 11.5 1.3 0.29 11.1 1.3 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.13 KIY50173.1 - 0.22 11.6 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Chitin_synth_2 PF03142.15 KIY50174.1 - 2.1e-247 821.9 0.0 2.8e-247 821.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KIY50174.1 - 9.2e-13 48.6 0.1 1.8e-11 44.4 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIY50174.1 - 4.8e-11 42.9 10.1 2.6e-10 40.5 8.2 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KIY50174.1 - 6.9e-05 22.9 0.3 0.023 14.8 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain LRR_4 PF12799.7 KIY50175.1 - 0.061 13.8 2.6 47 4.6 0.0 4.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) SDA1 PF05285.12 KIY50176.1 - 3.6e-86 289.7 36.2 4.2e-45 154.7 10.3 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KIY50176.1 - 8.4e-22 77.3 0.0 3.1e-21 75.4 0.0 2.1 2 0 0 2 2 2 1 NUC130/3NT domain CBFB_NFYA PF02045.15 KIY50177.1 - 2.5e-29 101.6 6.4 2.9e-29 101.5 6.4 1.0 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B HeH PF12949.7 KIY50178.1 - 3.4e-05 23.5 0.2 6.4e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 HeH/LEM domain Armet PF10208.9 KIY50178.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding SAP PF02037.27 KIY50178.1 - 0.053 13.3 2.2 1.2 9.0 0.1 2.7 3 0 0 3 3 3 0 SAP domain DUF1279 PF06916.13 KIY50179.1 - 3.7e-18 65.9 0.1 5e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) RPEL PF02755.15 KIY50180.1 - 1.2e-16 59.7 3.3 2.7e-09 36.4 0.6 2.7 2 1 0 2 2 2 2 RPEL repeat SAM_decarbox PF01536.16 KIY50182.1 - 1.3e-118 396.1 0.0 1.5e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase PP2C PF00481.21 KIY50183.1 - 5.8e-14 52.3 0.0 9.7e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Zn_clus PF00172.18 KIY50184.1 - 3.3e-11 43.1 28.7 2.3e-05 24.4 8.0 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Dfp1_Him1_M PF08630.10 KIY50186.1 - 3.5e-35 121.0 0.0 8.5e-35 119.7 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KIY50186.1 - 1.2e-17 63.8 0.3 2.7e-17 62.6 0.3 1.7 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KIY50186.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KIY50186.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain zf-met PF12874.7 KIY50186.1 - 1.9 9.0 3.9 22 5.6 3.9 2.5 1 1 0 1 1 1 0 Zinc-finger of C2H2 type APG5 PF04106.12 KIY50187.1 - 7e-62 209.0 0.0 9.7e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF1115 PF06544.12 KIY50187.1 - 0.16 12.1 0.4 9.1 6.4 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1115) zf-C2H2_2 PF12756.7 KIY50188.1 - 4.7e-37 126.4 10.9 9.5e-31 106.1 0.8 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KIY50188.1 - 2.3e-08 34.1 19.5 2.4e-08 34.0 2.9 4.1 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY50188.1 - 3.2e-08 33.7 1.7 3.2e-08 33.7 1.7 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIY50188.1 - 0.0034 18.1 19.7 0.16 12.9 0.1 4.7 4 1 0 4 4 4 3 C2H2-type zinc finger Rtf2 PF04641.12 KIY50188.1 - 0.0047 16.3 1.2 0.0083 15.5 1.2 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-DBF PF07535.12 KIY50188.1 - 0.035 14.2 0.7 0.035 14.2 0.7 2.8 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2 PF00096.26 KIY50188.1 - 0.076 13.5 0.3 0.076 13.5 0.3 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Rax2 PF12768.7 KIY50189.1 - 1.1e-46 159.1 10.4 8.5e-45 152.8 4.4 5.1 5 2 1 6 6 6 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 KIY50189.1 - 2.6e-11 43.0 0.0 5.3e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY50189.1 - 1.2e-08 34.6 0.4 2.6e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF5122 PF17164.4 KIY50189.1 - 0.00084 19.6 24.7 7.2 7.0 0.0 9.9 8 1 1 9 9 9 1 Domain of unknown function (DUF5122) beta-propeller SH3_2 PF07653.17 KIY50189.1 - 0.0031 17.1 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rhomboid PF01694.22 KIY50189.1 - 0.0053 16.8 1.7 0.026 14.5 1.7 2.2 1 0 0 1 1 1 1 Rhomboid family Kelch_6 PF13964.6 KIY50189.1 - 0.13 12.6 16.2 2.4 8.6 0.1 7.1 7 0 0 7 7 7 0 Kelch motif AvrRpt-cleavage PF05627.11 KIY50189.1 - 0.14 11.5 0.2 0.31 10.4 0.2 1.6 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr Kelch_2 PF07646.15 KIY50189.1 - 0.71 9.9 10.5 4.5 7.4 0.0 5.5 7 0 0 7 7 7 0 Kelch motif AA_permease PF00324.21 KIY50190.1 - 3.5e-120 401.8 31.4 4.2e-120 401.6 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY50190.1 - 1.9e-35 122.5 34.4 2.2e-35 122.3 34.4 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 KIY50190.1 - 0.0023 16.8 10.2 0.028 13.3 7.6 2.5 2 0 0 2 2 2 2 Spore germination protein DUF5490 PF17593.2 KIY50190.1 - 0.055 13.5 0.1 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5490) SpoVAB PF13782.6 KIY50190.1 - 1.4 9.2 8.6 0.84 10.0 1.5 2.6 2 0 0 2 2 2 0 Stage V sporulation protein AB p450 PF00067.22 KIY50191.1 - 0.014 14.2 0.0 0.065 12.0 0.0 1.8 2 0 0 2 2 2 0 Cytochrome P450 DUF5445 PF17520.2 KIY50192.1 - 0.009 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5445) adh_short_C2 PF13561.6 KIY50192.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Bac_rhamnosid6H PF17389.2 KIY50193.1 - 1.9e-15 57.0 0.1 2.9e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KIY50193.1 - 7.5e-06 25.7 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 KIY50193.1 - 8e-05 22.0 1.7 0.00013 21.3 1.7 1.3 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Trehalase PF01204.18 KIY50193.1 - 0.0044 15.9 0.4 0.0064 15.4 0.4 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 KIY50193.1 - 0.012 14.6 0.5 0.03 13.3 0.5 1.6 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Ribosomal_S13 PF00416.22 KIY50194.1 - 2.6e-55 186.3 3.2 3e-55 186.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KIY50194.1 - 0.0024 16.7 0.0 0.013 14.3 0.0 1.7 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KIY50194.1 - 0.036 14.3 0.1 0.11 12.7 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif Period_C PF12114.8 KIY50194.1 - 0.09 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Glyco_transf_20 PF00982.21 KIY50195.1 - 7.6e-134 446.9 0.0 9.7e-134 446.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KIY50195.1 - 2.6e-19 69.3 0.0 4.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 KIY50195.1 - 0.017 14.8 0.1 0.35 10.5 0.1 2.3 2 0 0 2 2 2 0 Starch synthase catalytic domain Arf PF00025.21 KIY50196.1 - 7.5e-78 260.0 0.0 8.5e-78 259.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIY50196.1 - 2.4e-15 56.8 0.1 3.2e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIY50196.1 - 4e-13 49.3 0.0 4.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KIY50196.1 - 8.1e-12 45.0 1.6 1.6e-07 30.9 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIY50196.1 - 1.2e-11 44.4 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY50196.1 - 1.7e-09 37.4 0.0 2.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY50196.1 - 0.0001 22.3 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KIY50196.1 - 0.014 14.7 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MobB PF03205.14 KIY50196.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CUE PF02845.16 KIY50197.1 - 3.3e-09 36.3 0.0 5.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain Rhomboid PF01694.22 KIY50197.1 - 7.2e-05 22.8 8.6 0.00011 22.2 8.6 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KIY50197.1 - 0.0019 18.7 0.8 0.0033 18.0 0.8 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Ank_5 PF13857.6 KIY50197.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) LRR_4 PF12799.7 KIY50198.1 - 8.6e-11 41.9 11.6 3.4e-05 24.1 4.6 5.3 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY50198.1 - 9.5e-09 34.9 10.1 8.9e-08 31.8 5.9 3.2 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.6 KIY50198.1 - 0.00017 21.1 0.5 0.00065 19.2 0.5 1.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KIY50198.1 - 0.45 11.3 7.6 5.8 7.9 0.3 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat GalP_UDP_transf PF01087.22 KIY50199.1 - 1.6e-58 198.2 0.0 1.8e-57 194.8 0.1 2.4 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KIY50199.1 - 1.6e-46 158.1 0.0 9.7e-45 152.3 0.0 2.8 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KIY50199.1 - 0.015 16.0 0.0 0.06 14.1 0.0 2.0 1 1 0 1 1 1 0 HIT domain DUF4921 PF16268.5 KIY50199.1 - 0.037 12.9 0.1 3.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) HMMR_C PF15908.5 KIY50200.1 - 0.00032 21.0 2.2 0.00032 21.0 2.2 5.7 1 1 4 6 6 6 1 Hyaluronan mediated motility receptor C-terminal Seryl_tRNA_N PF02403.22 KIY50200.1 - 0.0011 19.2 3.0 0.0011 19.2 3.0 6.9 3 2 3 7 7 7 1 Seryl-tRNA synthetase N-terminal domain Yuri_gagarin PF15934.5 KIY50200.1 - 0.002 18.0 4.7 0.002 18.0 4.7 4.2 1 1 3 4 4 4 1 Yuri gagarin DUF1515 PF07439.11 KIY50200.1 - 0.021 14.8 2.1 0.021 14.8 2.1 4.3 3 2 2 5 5 5 0 Protein of unknown function (DUF1515) TIR_2 PF13676.6 KIY50200.1 - 0.047 14.3 3.8 2.7 8.6 0.6 3.1 2 1 1 3 3 3 0 TIR domain NAPRTase_N PF17767.1 KIY50200.1 - 0.19 12.1 1.2 0.67 10.4 0.2 2.4 2 1 1 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain HALZ PF02183.18 KIY50200.1 - 0.48 10.7 0.1 0.48 10.7 0.1 6.6 9 1 0 9 9 9 0 Homeobox associated leucine zipper HMMR_N PF15905.5 KIY50200.1 - 0.66 9.4 60.7 0.4 10.1 10.9 4.9 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 KIY50200.1 - 2.4 6.4 67.0 5.3 5.3 28.0 3.3 1 1 2 3 3 3 0 Mitotic checkpoint protein MFS_1 PF07690.16 KIY50201.1 - 4.3e-46 157.4 47.9 5.2e-33 114.4 16.5 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY50201.1 - 2.3e-05 23.5 8.2 2.3e-05 23.5 8.2 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KIY50201.1 - 0.00066 18.2 13.4 0.0015 17.0 8.0 2.5 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) CrgA PF06781.12 KIY50201.1 - 0.076 13.1 1.0 0.83 9.7 0.2 2.9 2 0 0 2 2 2 0 Cell division protein CrgA DUF3784 PF12650.7 KIY50201.1 - 0.25 11.6 0.2 0.25 11.6 0.2 4.3 4 1 2 6 6 6 0 Domain of unknown function (DUF3784) DUF1774 PF08611.10 KIY50201.1 - 0.61 10.4 4.8 5.3 7.4 0.0 3.5 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) DUF21 PF01595.20 KIY50201.1 - 2.5 7.8 7.3 0.55 9.9 0.8 2.7 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain OATP PF03137.20 KIY50201.1 - 4.7 5.4 21.1 0.12 10.6 0.7 4.1 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family UBA PF00627.31 KIY50202.1 - 1.9e-30 104.3 4.8 1.2e-15 57.0 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KIY50202.1 - 1.4e-20 72.8 0.2 2.3e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 KIY50202.1 - 3.4e-17 61.9 11.2 3.4e-17 61.9 11.2 1.9 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.8 KIY50202.1 - 1.6e-07 31.1 0.7 2.6e-07 30.4 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 KIY50202.1 - 0.0032 17.2 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 CUE domain Ubiquitin_5 PF18037.1 KIY50202.1 - 0.004 17.5 0.2 0.0077 16.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KIY50202.1 - 0.012 16.0 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain MSP1a PF11670.8 KIY50202.1 - 2.4 7.4 0.0 2.4 7.4 0.0 2.8 2 1 1 3 3 3 0 Major surface protein 1a (MSP1a) Pre-SET PF05033.16 KIY50204.1 - 1.6e-18 67.3 3.9 1.6e-18 67.3 3.9 2.2 2 1 0 2 2 2 1 Pre-SET motif SET PF00856.28 KIY50204.1 - 3e-17 63.5 0.0 1e-16 61.8 0.0 1.9 1 1 0 1 1 1 1 SET domain ParA PF10609.9 KIY50206.1 - 5.1e-80 268.5 0.1 6.2e-80 268.2 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIY50206.1 - 1.3e-14 54.4 0.0 6.2e-14 52.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KIY50206.1 - 9e-10 38.7 2.4 5.9e-08 32.8 0.5 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KIY50206.1 - 1.3e-05 24.6 0.2 2.2e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 KIY50206.1 - 0.00043 19.9 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KIY50206.1 - 0.0015 17.8 0.7 0.0015 17.8 0.7 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KIY50206.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 KIY50206.1 - 0.039 13.3 0.1 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 VirC1 protein CLP1_P PF16575.5 KIY50206.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MFS_1 PF07690.16 KIY50207.1 - 3e-35 121.8 31.5 2.6e-34 118.7 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CcmH PF03918.14 KIY50207.1 - 0.24 10.7 0.6 0.6 9.4 0.1 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF5392 PF17370.2 KIY50207.1 - 0.89 9.6 5.6 1.7 8.7 0.5 3.2 3 1 0 4 4 4 0 Family of unknown function (DUF5392) p450 PF00067.22 KIY50208.1 - 5.6e-71 239.7 0.0 7.1e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NYN_YacP PF05991.11 KIY50208.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 2 0 0 2 2 2 0 YacP-like NYN domain AOX PF01786.17 KIY50209.1 - 5e-93 310.6 0.0 6.2e-93 310.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Git3 PF11710.8 KIY50210.1 - 0.00011 22.1 10.0 0.00042 20.2 10.0 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KIY50210.1 - 0.012 15.0 10.2 0.018 14.4 10.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) AA_permease PF00324.21 KIY50211.1 - 6.1e-120 401.0 33.1 7.3e-120 400.8 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY50211.1 - 4e-35 121.5 36.0 4.8e-35 121.2 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 KIY50211.1 - 0.0053 15.6 11.2 0.081 11.7 8.8 2.6 2 0 0 2 2 2 2 Spore germination protein DUF5490 PF17593.2 KIY50211.1 - 0.075 13.1 0.1 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5490) SpoVAB PF13782.6 KIY50211.1 - 1.5 9.1 8.7 0.62 10.4 0.9 2.7 2 0 0 2 2 2 0 Stage V sporulation protein AB RF-1 PF00472.20 KIY50212.1 - 1.1e-21 77.0 1.6 1.6e-21 76.4 1.6 1.1 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 KIY50212.1 - 0.066 13.6 0.2 0.19 12.2 0.1 1.8 1 1 0 2 2 2 0 Mitochondrial ribosomal subunit protein CTP_transf_like PF01467.26 KIY50212.1 - 0.081 13.1 0.2 0.14 12.4 0.2 1.4 1 0 0 1 1 1 0 Cytidylyltransferase-like UQ_con PF00179.26 KIY50213.1 - 1.2e-41 141.6 0.0 1.4e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIY50213.1 - 0.006 16.4 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 UEV domain Complex1_LYR PF05347.15 KIY50213.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) p450 PF00067.22 KIY50214.1 - 2.2e-48 165.2 0.0 7.4e-47 160.1 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 ThiF PF00899.21 KIY50216.1 - 5.1e-14 52.2 0.0 1.2e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 ThiF family E1_4HB PF16191.5 KIY50216.1 - 0.02 15.1 0.3 6.3 7.1 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle OPT PF03169.15 KIY50217.1 - 4.9e-176 587.0 53.6 5.6e-176 586.8 53.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4227 PF14004.6 KIY50217.1 - 0.064 13.2 0.6 0.28 11.2 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) BofA PF07441.11 KIY50217.1 - 8.1 6.7 12.0 1.1 9.5 6.5 2.6 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA YL1_C PF08265.11 KIY50218.1 - 5.7e-16 58.0 0.4 5.7e-16 58.0 0.4 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Msap1 PF17077.5 KIY50218.1 - 0.075 12.2 0.5 0.09 11.9 0.5 1.1 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 LysM PF01476.20 KIY50219.1 - 1.6e-10 40.8 0.3 5.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 LysM domain Chitin_synth_1 PF01644.17 KIY50220.1 - 1.9e-67 226.3 0.1 3.2e-67 225.6 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIY50220.1 - 4.4e-27 93.8 0.2 8.5e-27 92.9 0.2 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIY50220.1 - 2e-13 49.8 0.4 2e-05 23.4 0.1 3.4 3 0 0 3 3 3 3 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY50220.1 - 0.0003 20.8 13.6 0.00033 20.6 0.3 3.2 1 1 1 2 2 2 1 Glycosyl transferase family group 2 BING4CT PF08149.11 KIY50221.1 - 5.1e-36 122.3 0.0 7e-35 118.7 0.0 2.8 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 KIY50221.1 - 7.4e-05 23.4 1.9 0.00039 21.2 0.0 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.6 KIY50221.1 - 0.028 14.0 0.0 0.08 12.5 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KIY50221.1 - 0.031 14.6 0.0 4.7 7.6 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1348 PF07080.11 KIY50222.1 - 2.2e-60 202.3 6.4 2.5e-60 202.1 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KIY50222.1 - 3.1e-05 24.6 0.1 4.1e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIY50222.1 - 0.00078 19.8 0.0 0.0017 18.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3648 PF12364.8 KIY50222.1 - 0.17 12.1 0.1 0.4 10.9 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3648) CPL PF08144.11 KIY50223.1 - 8.6e-36 123.4 0.1 3.5e-32 111.7 0.0 3.9 3 1 0 3 3 3 3 CPL (NUC119) domain CN_hydrolase PF00795.22 KIY50224.1 - 7.2e-52 176.3 0.0 8.1e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyoxal_oxid_N PF07250.11 KIY50225.1 - 1.2e-29 103.2 1.6 7.1e-14 51.6 0.1 5.0 3 1 2 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIY50225.1 - 2.2e-20 72.7 0.2 7.4e-20 71.1 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Podoplanin PF05808.11 KIY50225.1 - 0.019 15.1 3.8 0.038 14.1 3.8 1.4 1 0 0 1 1 1 0 Podoplanin DUF3681 PF12442.8 KIY50225.1 - 0.028 14.9 0.5 0.059 13.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) Kelch_4 PF13418.6 KIY50225.1 - 0.064 13.3 0.8 4 7.5 0.1 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Amnionless PF14828.6 KIY50225.1 - 0.088 11.6 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Amnionless TIP49 PF06068.13 KIY50226.1 - 1e-153 511.7 0.1 1.2e-153 511.5 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KIY50226.1 - 5.8e-18 64.8 0.0 1.3e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KIY50226.1 - 3.1e-08 34.1 0.1 0.00016 22.1 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIY50226.1 - 2.9e-07 30.4 0.0 1.5e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIY50226.1 - 0.00024 21.4 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIY50226.1 - 0.00051 20.5 0.0 0.0045 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIY50226.1 - 0.0045 17.0 0.1 2.5 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIY50226.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIY50226.1 - 0.037 14.3 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIY50226.1 - 0.078 13.3 0.3 0.52 10.6 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY50226.1 - 0.089 13.0 0.0 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ion_trans PF00520.31 KIY50227.1 - 5.7e-07 29.0 1.7 8.7e-07 28.4 1.7 1.2 1 0 0 1 1 1 1 Ion transport protein SPATA24 PF15175.6 KIY50227.1 - 0.0027 17.7 2.8 0.014 15.3 1.3 2.1 2 0 0 2 2 2 1 Spermatogenesis-associated protein 24 DUF4064 PF13273.6 KIY50227.1 - 0.0038 17.5 0.6 0.007 16.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Connexin PF00029.19 KIY50227.1 - 0.43 10.3 1.4 1.3 8.7 0.0 2.2 2 1 0 2 2 2 0 Connexin Rad17 PF03215.15 KIY50228.1 - 2.4e-26 92.8 0.0 4.3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KIY50228.1 - 0.00018 21.9 0.0 0.00049 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY50228.1 - 0.00074 19.8 0.0 0.0058 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY50228.1 - 0.00082 19.1 0.0 0.0027 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIY50228.1 - 0.0015 19.0 0.0 0.0055 17.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 KIY50228.1 - 0.0023 18.3 0.0 0.0053 17.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KIY50228.1 - 0.02 15.2 0.1 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIY50228.1 - 0.031 13.3 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_assoc_2 PF16193.5 KIY50228.1 - 0.037 14.4 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain ATPase_2 PF01637.18 KIY50228.1 - 0.073 13.0 0.0 0.84 9.5 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KIY50228.1 - 0.077 13.2 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF3741 PF12552.8 KIY50228.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) AAA_7 PF12775.7 KIY50228.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 KIY50228.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region ThiF PF00899.21 KIY50229.1 - 2.1e-71 240.1 0.0 3e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KIY50229.1 - 1.6e-14 54.4 0.4 1.8e-08 34.7 0.0 2.3 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 KIY50229.1 - 1.8e-06 28.4 0.0 3.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 KIY50229.1 - 0.0085 16.5 0.0 0.04 14.4 0.0 2.2 2 1 0 2 2 2 1 Putative NAD(P)-binding AAA_13 PF13166.6 KIY50229.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain HMG_box PF00505.19 KIY50232.1 - 7.5e-12 45.5 2.7 1.3e-11 44.7 2.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY50232.1 - 0.00048 20.7 2.8 0.00087 19.8 2.8 1.5 1 0 0 1 1 1 1 HMG-box domain DUF1804 PF08822.11 KIY50232.1 - 0.0033 17.4 0.5 0.0058 16.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) Whi5 PF08528.11 KIY50233.1 - 2e-05 24.1 0.1 3.8e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Whi5 like RNB PF00773.19 KIY50234.1 - 9e-99 330.9 0.1 1.2e-98 330.4 0.1 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KIY50234.1 - 3.1e-28 98.4 0.1 7e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KIY50234.1 - 9.4e-22 76.8 2.8 9.4e-22 76.8 2.8 1.9 2 0 0 2 2 2 1 S1 domain OB_Dis3 PF17849.1 KIY50234.1 - 8e-17 61.0 0.0 2.2e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KIY50234.1 - 1.9e-10 41.1 0.0 5.1e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 KIY50234.1 - 5.9e-09 36.0 2.4 2e-05 24.7 0.0 4.3 4 1 1 5 5 5 2 Cold shock domain OB_RNB PF08206.11 KIY50234.1 - 0.0078 15.9 1.0 0.2 11.3 0.0 3.0 3 0 0 3 3 3 1 Ribonuclease B OB domain VHS PF00790.19 KIY50235.1 - 5.1e-37 126.9 0.0 4.8e-36 123.7 0.0 2.3 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KIY50235.1 - 1.3e-19 70.3 0.7 5.5e-19 68.3 0.1 2.4 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 KIY50235.1 - 0.014 15.0 0.1 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 GGA N-GAT domain polyprenyl_synt PF00348.17 KIY50236.1 - 3e-61 206.7 0.0 7.4e-57 192.3 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KIY50236.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Peptidase_M20 PF01546.28 KIY50237.1 - 6.8e-28 97.8 0.0 1.6e-27 96.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY50237.1 - 1.1e-11 44.6 0.0 3e-11 43.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY50237.1 - 4.7e-05 23.2 0.0 0.00011 22.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 VPS9 PF02204.18 KIY50238.1 - 2.9e-17 62.8 0.0 5.4e-15 55.5 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain RPN6_N PF18055.1 KIY50239.1 - 6.9e-39 132.8 2.2 1.4e-38 131.8 0.1 2.4 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KIY50239.1 - 2.1e-16 60.3 0.2 7.4e-16 58.6 0.2 2.0 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 KIY50239.1 - 5.7e-09 35.6 0.7 1.5e-08 34.2 0.7 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain Wtap PF17098.5 KIY50239.1 - 0.039 13.9 0.4 0.082 12.8 0.1 1.7 2 0 0 2 2 2 0 WTAP/Mum2p family TPR_MalT PF17874.1 KIY50239.1 - 0.044 13.2 3.9 0.065 12.6 0.3 2.2 2 0 0 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 KIY50239.1 - 0.045 13.8 5.2 5.3 7.3 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY50239.1 - 0.2 11.6 0.5 4.5 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M15_2 PF05951.13 KIY50239.1 - 0.26 11.0 0.7 1.5 8.4 0.2 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF882) 3-HAO PF06052.12 KIY50240.1 - 1.3e-59 200.2 0.1 2e-57 193.1 0.1 2.0 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase p450 PF00067.22 KIY50241.1 - 7e-68 229.5 0.0 6.2e-67 226.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 zf-RING_2 PF13639.6 KIY50242.1 - 2.5e-05 24.5 0.5 3.3e-05 24.1 0.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KIY50242.1 - 0.00023 20.8 0.2 0.00034 20.3 0.2 1.2 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KIY50242.1 - 0.0077 16.2 1.0 0.011 15.7 1.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY50242.1 - 0.087 12.7 0.7 0.12 12.2 0.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UQ_con PF00179.26 KIY50243.1 - 4.2e-48 162.6 0.0 4.7e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY50243.1 - 0.00015 21.5 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KIY50243.1 - 0.019 14.9 0.1 0.037 13.9 0.1 1.5 1 1 0 1 1 1 0 UEV domain Hexapep PF00132.24 KIY50244.1 - 9.1e-10 37.9 12.9 0.00084 19.0 0.0 3.9 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KIY50244.1 - 0.42 10.4 12.7 0.54 10.1 0.3 3.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase TRAP_alpha PF03896.16 KIY50245.1 - 0.057 12.6 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM199X PF15814.5 KIY50245.1 - 0.068 12.2 0.8 0.094 11.8 0.8 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF1180 PF06679.12 KIY50245.1 - 1.8 9.0 4.5 0.51 10.7 0.9 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Hydrolase_4 PF12146.8 KIY50246.1 - 1.6e-08 34.1 0.1 8.9e-06 25.1 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 KIY50246.1 - 7.4e-05 22.8 0.1 0.0081 16.1 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KIY50246.1 - 9.3e-05 22.2 0.1 0.0018 18.0 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIY50246.1 - 0.0002 21.3 0.2 0.27 11.0 0.1 3.1 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KIY50246.1 - 0.0005 20.7 0.0 0.0012 19.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 KIY50246.1 - 0.023 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 KIY50246.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KIY50246.1 - 0.19 11.3 0.0 3.2 7.2 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Methyltransf_2 PF00891.18 KIY50250.1 - 9.3e-13 48.0 0.0 1e-10 41.3 0.0 2.6 2 1 1 3 3 3 1 O-methyltransferase domain MarR_2 PF12802.7 KIY50250.1 - 0.00093 19.0 0.1 0.0053 16.6 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 KIY50250.1 - 0.008 16.0 0.1 0.16 11.8 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_IclR PF09339.10 KIY50250.1 - 0.013 15.3 0.1 0.054 13.3 0.1 2.1 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_20 PF12840.7 KIY50250.1 - 0.028 14.5 0.1 0.091 12.8 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KIY50250.1 - 0.073 13.1 0.0 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Rrf2 PF02082.20 KIY50250.1 - 0.086 13.2 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator YscK PF06578.12 KIY50250.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) HTH_7 PF02796.15 KIY50250.1 - 0.2 11.8 0.0 0.73 10.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Skp1_POZ PF03931.15 KIY50251.1 - 0.00055 20.0 0.0 0.0015 18.7 0.0 1.7 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Metallophos PF00149.28 KIY50252.1 - 1.7e-30 107.1 0.0 2.8e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FMO-like PF00743.19 KIY50253.1 - 5.9e-26 91.0 0.0 6.6e-24 84.2 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY50253.1 - 2.8e-12 46.5 0.0 1.1e-08 34.8 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY50253.1 - 4e-10 39.4 0.0 2.2e-08 33.7 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY50253.1 - 1.4e-08 34.3 0.0 2.3e-06 27.0 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIY50253.1 - 2.4e-07 30.9 0.6 0.00044 20.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KIY50253.1 - 8.9e-06 25.5 4.9 0.0037 16.9 0.2 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY50253.1 - 1.7e-05 24.9 0.0 3.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIY50253.1 - 0.00049 19.5 0.4 2.7 7.2 0.0 3.3 3 1 0 3 3 3 2 Flavin containing amine oxidoreductase Glu_dehyd_C PF16912.5 KIY50253.1 - 0.003 17.1 0.0 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 KIY50253.1 - 0.0087 16.6 0.3 0.43 11.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY50253.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KIY50253.1 - 0.061 13.8 0.0 4 7.9 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KIY50253.1 - 0.074 13.1 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 KIY50254.1 - 1.7e-49 168.5 1.8 2.2e-49 168.2 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY50254.1 - 1.7e-36 125.5 0.8 2.2e-36 125.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY50254.1 - 3.6e-10 40.0 0.2 5.1e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIY50254.1 - 0.017 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KIY50255.1 - 2.1e-25 89.7 0.1 4.7e-25 88.6 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain TPP_enzyme_N PF02776.18 KIY50256.1 - 1.6e-29 102.7 0.0 2.7e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIY50256.1 - 5.3e-18 65.1 0.0 1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KIY50256.1 - 3.9e-09 36.5 0.0 8.5e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Trypsin_2 PF13365.6 KIY50257.1 - 0.027 15.3 0.1 1.8 9.4 0.0 2.6 2 1 0 2 2 2 0 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 KIY50257.1 - 0.067 12.4 0.5 0.29 10.3 0.1 2.1 3 0 0 3 3 3 0 Equine arteritis virus serine endopeptidase S32 SelP_N PF04592.14 KIY50258.1 - 6.3 6.1 26.4 0.91 8.9 9.1 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Cellulase PF00150.18 KIY50259.1 - 7.9e-12 45.2 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fis1_TPR_N PF14852.6 KIY50260.1 - 0.23 11.2 2.4 0.28 10.9 0.2 2.1 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat RSN1_7TM PF02714.15 KIY50261.1 - 3e-78 262.9 24.2 6.1e-78 261.9 24.2 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KIY50261.1 - 1.6e-35 122.9 0.0 2.5e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIY50261.1 - 6.6e-33 113.7 0.6 6.6e-33 113.7 0.6 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Cation_efflux PF01545.21 KIY50262.1 - 4.1e-14 52.8 7.7 5.1e-14 52.5 7.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIY50262.1 - 7.5e-10 38.8 0.2 1.3e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF3829 PF12889.7 KIY50262.1 - 0.078 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF1011 PF06237.12 KIY50262.1 - 0.16 12.3 1.0 0.33 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) zf-CCCH_2 PF14608.6 KIY50263.1 - 2.5e-13 50.0 36.7 3.6e-05 24.1 5.8 4.2 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KIY50263.1 - 9.1 6.5 21.2 0.86 9.8 0.6 5.1 4 1 1 5 5 5 0 Zinc finger domain iPGM_N PF06415.13 KIY50265.1 - 1.3e-75 253.6 0.0 2e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KIY50265.1 - 7.7e-71 238.3 0.2 9.3e-71 238.1 0.2 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KIY50265.1 - 6e-08 32.4 0.0 2.4e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KIY50265.1 - 9.7e-06 25.4 0.0 3e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 KIY50265.1 - 0.0038 16.2 0.2 0.024 13.6 0.1 2.1 2 0 0 2 2 2 1 Alkaline phosphatase PglZ PF08665.12 KIY50265.1 - 0.022 14.9 0.1 0.055 13.6 0.1 1.7 1 1 0 1 1 1 0 PglZ domain Cyclin_N PF00134.23 KIY50267.1 - 1.4e-11 44.3 0.0 1.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY50267.1 - 2e-07 31.5 0.0 3.5e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Cyclin Zeta_toxin PF06414.12 KIY50268.1 - 0.0022 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Torsin PF06309.11 KIY50268.1 - 0.0024 18.0 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Torsin NB-ARC PF00931.22 KIY50268.1 - 0.015 14.5 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KIY50268.1 - 0.031 14.4 0.0 0.12 12.5 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KIY50268.1 - 0.049 14.0 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 KIY50268.1 - 0.051 12.8 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain RNA12 PF10443.9 KIY50268.1 - 0.095 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein AAA_7 PF12775.7 KIY50268.1 - 0.22 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Rer1 PF03248.13 KIY50269.1 - 1e-67 227.2 0.3 1.2e-67 226.9 0.3 1.1 1 0 0 1 1 1 1 Rer1 family DUF4395 PF14340.6 KIY50269.1 - 0.038 14.3 0.2 6.4 7.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) UPF0029 PF01205.19 KIY50270.1 - 2.4e-27 95.3 0.0 3.5e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 HEPN_AbiU2 PF18734.1 KIY50270.1 - 0.093 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 AbiU2 DUF1917 PF08939.10 KIY50271.1 - 5.1e-19 69.2 0.0 6.7e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) SAP PF02037.27 KIY50271.1 - 0.02 14.7 0.0 0.051 13.3 0.0 1.8 1 0 0 1 1 1 0 SAP domain Fcf1 PF04900.12 KIY50272.1 - 8.6e-38 128.7 1.9 1.4e-37 128.0 1.9 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KIY50272.1 - 1e-11 45.1 0.3 1.3e-10 41.6 0.0 2.0 2 0 0 2 2 2 1 PIN like domain CPSase_L_D2 PF02786.17 KIY50273.1 - 9.2e-99 329.2 0.0 1.1e-75 253.7 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KIY50273.1 - 9.2e-39 132.6 0.2 1.9e-38 131.6 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KIY50273.1 - 2.8e-16 59.6 0.0 6.8e-07 29.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIY50273.1 - 5.1e-11 42.5 0.0 4.8e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KIY50273.1 - 1e-08 35.0 0.0 0.00051 19.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KIY50273.1 - 7.2e-06 25.6 0.1 0.014 14.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KIY50273.1 - 0.0047 17.0 0.0 0.037 14.1 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.22 KIY50273.1 - 0.086 13.0 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 MGS-like domain Peptidase_M17_N PF02789.17 KIY50273.1 - 0.14 12.0 0.1 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain F-box-like PF12937.7 KIY50274.1 - 0.00035 20.4 4.4 0.00035 20.4 4.4 3.4 4 1 0 4 4 4 1 F-box-like DUF4588 PF15251.6 KIY50275.1 - 6.7e-05 22.8 0.5 0.00014 21.7 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) NPH3 PF03000.14 KIY50275.1 - 0.07 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 NPH3 family DAO PF01266.24 KIY50276.1 - 9.8e-39 133.9 0.1 1.1e-38 133.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY50276.1 - 2.1e-06 27.2 0.1 0.0016 17.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY50276.1 - 1.2e-05 25.5 0.0 8.1e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY50276.1 - 3.1e-05 24.4 0.1 0.0018 18.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY50276.1 - 0.00092 18.4 0.1 0.023 13.8 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KIY50276.1 - 0.0019 17.5 0.1 0.0097 15.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KIY50276.1 - 0.0024 16.6 0.0 0.48 9.1 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Shikimate_DH PF01488.20 KIY50276.1 - 0.003 17.6 0.0 0.0074 16.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KIY50276.1 - 0.0078 15.3 0.1 1.9 7.4 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Amino_oxidase PF01593.24 KIY50276.1 - 0.0092 15.3 0.1 0.33 10.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KIY50276.1 - 0.023 14.0 0.0 0.06 12.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY50276.1 - 0.05 12.8 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KIY50276.1 - 0.054 13.8 0.3 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KIY50276.1 - 0.094 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 KIY50276.1 - 0.099 12.6 0.2 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 KIY50276.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus K_oxygenase PF13434.6 KIY50276.1 - 0.23 10.6 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lyase_aromatic PF00221.19 KIY50277.1 - 6.1e-132 440.6 0.1 9.1e-132 440.0 0.1 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase Ints3 PF10189.9 KIY50277.1 - 0.034 13.4 0.1 0.053 12.8 0.1 1.2 1 0 0 1 1 1 0 Integrator complex subunit 3 Rieske PF00355.26 KIY50278.1 - 4.3e-11 42.6 0.0 7.8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KIY50278.1 - 3.1e-10 40.4 0.2 6.8e-10 39.3 0.2 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Cytochrom_B_C PF00032.17 KIY50279.1 - 2.7 8.3 8.6 0.14 12.5 0.3 3.0 3 1 0 4 4 4 0 Cytochrome b(C-terminal)/b6/petD CDC45 PF02724.14 KIY50280.1 - 0.088 11.1 5.1 0.1 10.9 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein WRNPLPNID PF15017.6 KIY50280.1 - 0.37 11.7 0.3 0.37 11.7 0.3 2.9 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box SWIB PF02201.18 KIY50281.1 - 3e-29 100.7 0.1 6.5e-29 99.6 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KIY50281.1 - 6e-05 22.9 0.9 0.00018 21.4 0.2 2.2 3 0 0 3 3 3 1 DEK C terminal domain ATLF PF07737.11 KIY50281.1 - 0.032 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain DUF572 PF04502.13 KIY50281.1 - 0.12 11.9 11.5 0.16 11.6 11.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.9 KIY50281.1 - 0.13 10.8 7.9 0.14 10.7 7.9 1.0 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 KIY50281.1 - 0.46 8.6 7.4 0.52 8.4 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4604 PF15377.6 KIY50281.1 - 0.81 10.1 16.0 1.2 9.6 16.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Apt1 PF10351.9 KIY50281.1 - 0.94 8.3 9.2 1.1 8.1 9.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 KIY50281.1 - 6.1 5.4 5.5 6.5 5.3 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 KIY50281.1 - 7.2 3.6 7.2 8.6 3.3 7.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sel1 PF08238.12 KIY50282.1 - 1.2e-23 83.0 30.8 4.8e-05 23.9 0.1 10.7 10 1 0 10 10 10 5 Sel1 repeat TPR_16 PF13432.6 KIY50282.1 - 0.0001 22.9 14.0 0.002 18.7 0.1 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY50282.1 - 0.15 12.2 0.1 0.15 12.2 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY50282.1 - 0.2 12.0 2.2 1.4 9.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY50282.1 - 0.69 10.7 8.6 1.2e+02 3.6 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY50282.1 - 7.4 6.6 9.5 0.92 9.5 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_4 PF13637.6 KIY50284.1 - 1.7e-05 25.3 0.6 0.059 14.0 0.0 4.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) DUF4371 PF14291.6 KIY50285.1 - 0.051 13.2 0.3 0.07 12.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) Spore_III_AB PF09548.10 KIY50285.1 - 0.1 12.7 0.3 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Cnn_1N PF07989.11 KIY50285.1 - 0.29 11.3 3.4 0.31 11.2 0.5 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 2-Hacid_dh_C PF02826.19 KIY50286.1 - 6.3e-44 149.5 0.0 8.2e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY50286.1 - 1.5e-16 60.3 0.0 1.9e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY50286.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KIY50286.1 - 0.16 11.9 0.0 2.3 8.2 0.0 2.0 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_transf_49 PF13896.6 KIY50287.1 - 1.3e-66 225.3 5.0 1.2e-54 185.9 0.6 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan BcrAD_BadFG PF01869.20 KIY50288.1 - 1.6e-17 63.9 0.0 2.4e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 KIY50288.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain FtsA PF14450.6 KIY50288.1 - 0.16 12.4 0.0 0.18 12.3 0.0 1.6 1 1 0 1 1 1 0 Cell division protein FtsA Cornichon PF03311.14 KIY50289.1 - 5.5e-45 152.6 4.7 6.1e-45 152.5 4.7 1.0 1 0 0 1 1 1 1 Cornichon protein Imp-YgjV PF10688.9 KIY50289.1 - 0.24 11.2 2.9 0.26 11.1 0.6 1.9 1 1 0 2 2 2 0 Bacterial inner membrane protein RRM_1 PF00076.22 KIY50290.1 - 0.00022 21.0 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY50290.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif FAD-oxidase_C PF02913.19 KIY50290.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain XPG_I_2 PF12813.7 KIY50291.1 - 3.2e-06 26.8 0.0 7.1e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 XPG domain containing NAD_kinase PF01513.21 KIY50292.1 - 4.9e-61 206.5 0.0 7.2e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KIY50292.1 - 0.031 13.9 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain BRCT PF00533.26 KIY50294.1 - 3.5e-05 24.1 0.0 4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KIY50294.1 - 8.6e-05 22.4 0.0 9.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KIY50294.1 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KIY50294.1 - 0.0005 20.4 0.0 0.00057 20.2 0.0 1.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Glyco_transf_17 PF04724.13 KIY50295.1 - 5e-137 456.6 0.0 6.1e-137 456.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 PH PF00169.29 KIY50296.1 - 4.4e-07 30.4 0.0 8.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Trp_halogenase PF04820.14 KIY50298.1 - 7.5e-30 104.2 0.1 7.5e-15 54.7 0.0 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIY50298.1 - 2.4e-14 53.3 0.0 9.3e-13 48.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIY50298.1 - 6.2e-06 26.3 0.5 0.00017 21.7 0.4 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIY50298.1 - 0.00027 19.8 0.4 0.00042 19.1 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KIY50298.1 - 0.00029 20.3 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY50298.1 - 0.00035 19.8 0.6 0.00072 18.7 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY50298.1 - 0.00054 19.3 0.1 0.00082 18.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY50298.1 - 0.0016 17.6 1.7 0.0031 16.6 1.7 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KIY50298.1 - 0.0019 17.8 0.5 0.016 14.8 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIY50298.1 - 0.0087 15.4 0.3 0.017 14.4 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY50298.1 - 0.029 14.9 0.0 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY50298.1 - 0.03 13.5 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KIY50298.1 - 0.031 13.6 0.1 0.065 12.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KIY50298.1 - 0.13 12.7 0.2 0.74 10.3 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KIY50298.1 - 0.13 11.3 0.2 0.24 10.4 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein LCAT PF02450.15 KIY50299.1 - 6.6e-65 219.8 0.7 4.3e-33 115.1 0.0 2.3 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase IGPS PF00218.21 KIY50300.1 - 2.1e-87 292.5 0.0 3.3e-87 291.9 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KIY50300.1 - 1e-42 146.1 0.0 1.6e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KIY50300.1 - 4.4e-41 140.8 0.1 2.1e-18 66.8 0.0 3.2 2 1 1 3 3 3 3 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KIY50300.1 - 4.5e-07 29.9 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.21 KIY50300.1 - 0.0087 15.5 0.1 0.042 13.3 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein QRPTase_C PF01729.19 KIY50300.1 - 0.15 11.9 0.2 0.95 9.2 0.1 2.4 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain adh_short PF00106.25 KIY50301.1 - 4.5e-43 147.0 3.0 5.8e-43 146.6 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY50301.1 - 2.2e-30 105.9 0.3 2.9e-30 105.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY50301.1 - 1.8e-10 41.1 0.8 9.2e-10 38.7 0.8 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY50301.1 - 0.0013 18.2 0.4 0.0019 17.7 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIY50301.1 - 0.0018 18.5 2.6 0.032 14.5 0.2 2.4 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KIY50301.1 - 0.003 16.7 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY50301.1 - 0.005 16.0 0.9 0.0095 15.1 0.9 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.6 KIY50301.1 - 0.039 13.8 0.1 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_trans_4_2 PF13477.6 KIY50301.1 - 0.054 13.5 0.1 7.7 6.5 0.0 2.6 1 1 2 3 3 3 0 Glycosyl transferase 4-like HpaB_N PF11794.8 KIY50301.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1776 PF08643.10 KIY50301.1 - 0.1 12.0 0.2 0.4 10.0 0.1 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) DUF724 PF05266.14 KIY50301.1 - 0.15 11.9 0.1 0.33 10.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) 4HBT_2 PF13279.6 KIY50302.1 - 1.2e-07 32.2 0.0 1.8e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily PAC3 PF10178.9 KIY50302.1 - 0.027 14.6 0.0 0.072 13.2 0.0 1.7 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 PP2C PF00481.21 KIY50303.1 - 1.9e-27 96.5 0.0 5e-26 91.9 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C TFIIF_alpha PF05793.12 KIY50304.1 - 0.34 9.5 4.0 0.71 8.4 4.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sec7 PF01369.20 KIY50305.1 - 3.6e-31 108.3 0.0 4.8e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KIY50305.1 - 0.13 12.3 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 PH domain Fe-ADH PF00465.19 KIY50306.1 - 4e-64 216.7 0.0 5.1e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIY50306.1 - 1.4e-16 61.0 0.0 1.7e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cation_efflux PF01545.21 KIY50307.1 - 3.9e-39 134.5 1.7 5.8e-39 133.9 1.7 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIY50307.1 - 1.7e-11 44.1 1.2 3.1e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Zip PF02535.22 KIY50307.1 - 0.0075 15.5 0.7 0.015 14.6 0.7 1.6 1 0 0 1 1 1 1 ZIP Zinc transporter Hist_deacetyl PF00850.19 KIY50308.1 - 5e-86 289.0 0.2 7.2e-86 288.4 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KIY50308.1 - 2.9e-39 134.8 0.1 4.2e-39 134.2 0.1 1.2 1 0 0 1 1 1 1 Arb2 domain Retrotrans_gag PF03732.17 KIY50309.1 - 4.9e-05 23.5 0.4 8.8e-05 22.7 0.2 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein Rad10 PF03834.14 KIY50311.1 - 3.2e-47 159.3 0.0 5.2e-47 158.6 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KIY50311.1 - 5.3e-06 26.9 0.0 1.3e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KIY50311.1 - 0.0039 17.3 0.0 0.042 13.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 KIY50311.1 - 0.042 14.1 0.1 0.23 11.8 0.0 2.2 2 1 0 2 2 2 0 Helix-hairpin-helix motif PALP PF00291.25 KIY50312.1 - 9.9e-77 258.2 0.2 1.2e-76 257.9 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KIY50312.1 - 3.3e-43 145.4 0.1 7.1e-25 86.6 0.0 2.6 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase HEPN_Toprim_N PF18871.1 KIY50313.1 - 0.13 12.2 6.8 0.22 11.4 6.8 1.3 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Presenilin PF01080.17 KIY50313.1 - 3 6.5 7.6 3.4 6.3 7.6 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 KIY50314.1 - 4.4e-61 206.5 0.0 5.1e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50314.1 - 8e-18 64.7 0.0 1.2e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY50314.1 - 4.1e-10 40.0 0.1 3.7e-06 27.0 0.1 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY50314.1 - 0.0011 17.9 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KIY50314.1 - 0.046 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2470 PF10615.9 KIY50315.1 - 2.7e-18 66.4 0.0 4.8e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KIY50315.1 - 3.7e-13 49.6 1.3 6.2e-13 48.9 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Clat_adaptor_s PF01217.20 KIY50316.1 - 1e-15 57.9 0.0 4.5e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain NDUF_B12 PF08122.12 KIY50317.1 - 5.4e-16 58.4 0.3 5.6e-16 58.3 0.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Topoisom_I PF01028.20 KIY50318.1 - 3.1e-95 317.8 5.7 7.6e-95 316.6 5.7 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KIY50318.1 - 5.5e-95 316.9 0.1 5.5e-95 316.9 0.1 2.9 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KIY50318.1 - 7.2e-36 122.0 1.1 9.7e-35 118.3 0.3 2.8 2 0 0 2 2 2 1 C-terminal topoisomerase domain Ndc1_Nup PF09531.10 KIY50318.1 - 4.3 5.9 4.5 7.4 5.1 4.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC_membrane PF00664.23 KIY50319.1 - 2.4e-95 319.3 17.8 6.3e-49 167.1 9.8 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY50319.1 - 1.6e-68 229.4 0.1 4.1e-33 114.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY50319.1 - 5.6e-15 55.4 0.1 2.5e-05 23.8 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIY50319.1 - 2.2e-07 30.1 2.0 0.0057 15.5 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KIY50319.1 - 8.6e-07 28.6 1.3 0.0026 17.5 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY50319.1 - 9.9e-07 29.3 1.8 0.0044 17.4 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIY50319.1 - 3.9e-06 26.9 1.2 0.23 11.2 0.1 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIY50319.1 - 4e-06 26.8 0.2 0.061 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY50319.1 - 6.8e-06 26.1 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KIY50319.1 - 1.3e-05 25.5 2.0 0.18 12.1 0.1 4.4 3 2 0 3 3 2 2 AAA domain AAA_23 PF13476.6 KIY50319.1 - 5.8e-05 23.7 1.0 0.079 13.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain G-alpha PF00503.20 KIY50319.1 - 0.00021 20.6 0.0 0.33 10.0 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 KIY50319.1 - 0.00024 20.7 0.0 0.9 9.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIY50319.1 - 0.00033 20.0 0.0 0.24 10.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 KIY50319.1 - 0.0011 18.8 1.6 1.2 8.8 0.1 3.4 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KIY50319.1 - 0.0015 18.7 3.3 1.8 8.9 0.6 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KIY50319.1 - 0.0025 17.4 0.7 0.87 9.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 KIY50319.1 - 0.0044 17.5 3.4 6.6 7.2 0.6 4.2 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIY50319.1 - 0.0061 17.1 0.0 7.4 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIY50319.1 - 0.0098 15.9 0.4 4.5 7.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KIY50319.1 - 0.014 15.6 1.8 1.8 8.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 KIY50319.1 - 0.025 14.3 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KIY50319.1 - 0.032 13.4 0.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 KIY50319.1 - 0.034 14.3 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIY50319.1 - 0.035 14.2 0.1 13 5.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KIY50319.1 - 0.04 14.3 0.0 7.4 7.0 0.0 3.4 4 0 0 4 4 3 0 RNA helicase DUF815 PF05673.13 KIY50319.1 - 0.043 13.0 0.1 9.3 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KIY50319.1 - 0.065 13.2 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 KIY50319.1 - 0.092 12.8 1.1 21 5.1 0.3 3.0 3 0 0 3 3 2 0 Helicase HerA, central domain APS_kinase PF01583.20 KIY50319.1 - 0.12 12.3 0.1 2.1 8.2 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF3325 PF11804.8 KIY50319.1 - 0.22 11.7 2.6 1.1 9.5 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) AAA_24 PF13479.6 KIY50319.1 - 0.24 11.1 1.7 12 5.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY50319.1 - 0.43 9.9 1.6 19 4.5 0.5 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC2_membrane_3 PF12698.7 KIY50319.1 - 2.5 7.1 17.6 5.3 6.1 5.8 3.4 3 0 0 3 3 3 0 ABC-2 family transporter protein Mg_trans_NIPA PF05653.14 KIY50320.1 - 1.7e-13 50.4 8.0 1.4e-08 34.2 3.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KIY50320.1 - 2.5e-07 31.0 17.6 4.7e-06 26.8 1.2 3.0 3 0 0 3 3 3 2 EamA-like transporter family TssO PF17561.2 KIY50320.1 - 0.77 9.9 3.0 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 Type VI secretion system, TssO HlyIII PF03006.20 KIY50320.1 - 8.9 5.9 9.4 0.16 11.7 0.9 2.2 2 1 0 2 2 2 0 Haemolysin-III related DUF4303 PF14136.6 KIY50321.1 - 0.023 14.4 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Myb_DNA-binding PF00249.31 KIY50322.1 - 7.2e-07 29.3 0.3 1.2e-06 28.6 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY50322.1 - 0.0027 17.9 0.6 0.0032 17.7 0.0 1.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4218 PF13960.6 KIY50323.1 - 0.00078 19.0 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Tcp11 PF05794.13 KIY50324.1 - 2.2e-13 50.1 0.0 1.3e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 T-complex protein 11 DUF3772 PF12607.8 KIY50324.1 - 0.075 12.8 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) stn_TNFRSF12A PF12191.8 KIY50325.1 - 0.42 10.8 1.6 0.5 10.6 0.6 1.6 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Alpha-amylase_C PF02806.18 KIY50326.1 - 1.5e-25 89.5 0.0 5.8e-25 87.6 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KIY50326.1 - 4e-19 68.8 0.0 1.1e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KIY50326.1 - 7.8e-15 55.3 0.4 3.3e-10 40.1 0.1 2.5 2 1 1 3 3 3 2 Alpha amylase, catalytic domain MFS_1 PF07690.16 KIY50327.1 - 1.1e-27 96.9 28.7 1.4e-27 96.5 28.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY50327.1 - 7.2e-13 48.2 19.4 1.5e-12 47.1 19.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Caps_synth_CapC PF14102.6 KIY50328.1 - 0.0056 17.1 1.3 0.0056 17.1 1.3 2.4 2 0 0 2 2 2 1 Capsule biosynthesis CapC VMA21 PF09446.10 KIY50328.1 - 0.026 14.6 5.7 0.037 14.1 1.9 2.9 2 1 0 2 2 2 0 VMA21-like domain CHCH PF06747.13 KIY50329.1 - 1.7e-08 34.4 5.8 3.2e-08 33.5 5.8 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KIY50329.1 - 0.00027 21.3 1.6 0.00039 20.8 1.6 1.2 1 0 0 1 1 1 1 GCK domain CX9C PF16860.5 KIY50329.1 - 0.028 14.4 1.1 0.057 13.4 1.1 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MCM PF00493.23 KIY50330.1 - 1.6e-99 331.5 0.0 2.3e-99 331.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY50330.1 - 1.3e-36 125.2 0.0 2.4e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KIY50330.1 - 1.8e-30 106.3 23.8 1.8e-30 106.3 23.8 2.8 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KIY50330.1 - 9.3e-25 86.9 0.3 3e-24 85.2 0.3 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIY50330.1 - 2.4e-12 47.4 0.0 6.6e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIY50330.1 - 6.7e-08 32.2 0.0 2.1e-06 27.3 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIY50330.1 - 1.6e-06 28.1 0.0 3.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIY50330.1 - 0.0027 17.6 0.1 0.033 14.0 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIY50330.1 - 0.0049 16.6 0.1 0.035 13.8 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 KIY50330.1 - 0.12 13.1 0.1 0.35 11.5 0.1 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain TGT PF01702.18 KIY50331.1 - 3.1e-111 371.9 0.0 9.5e-110 367.0 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase tRNA-synt_1b PF00579.25 KIY50332.1 - 1.7e-73 247.5 0.0 2.2e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KIY50332.1 - 0.0017 18.2 0.3 0.21 11.4 0.3 2.5 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 KIY50332.1 - 0.039 13.7 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 S4 domain DNA_ligase_A_M PF01068.21 KIY50333.1 - 1.6e-27 96.5 0.6 3.3e-27 95.4 0.6 1.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIY50333.1 - 3.5e-12 47.0 0.0 8.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KIY50333.1 - 0.0013 19.1 0.1 0.0021 18.4 0.1 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KIY50333.1 - 0.018 14.9 0.3 0.059 13.2 0.1 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Ribosom_S12_S23 PF00164.25 KIY50334.1 - 6.5e-48 161.1 0.9 8.2e-48 160.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 GPI-anchored PF10342.9 KIY50335.1 - 4.1e-08 33.9 0.2 4.9e-08 33.6 0.2 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KIY50335.1 - 0.0013 18.5 0.1 0.0014 18.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF5460 PF17544.2 KIY50335.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5460) EMP70 PF02990.16 KIY50336.1 - 1.7e-187 624.2 0.3 1.7e-187 624.2 0.3 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 TMEM40 PF15817.5 KIY50336.1 - 1.1 9.0 3.7 3.9 7.2 3.7 1.9 1 0 0 1 1 1 0 Transmembrane protein 40 family Pyr_redox_2 PF07992.14 KIY50337.1 - 2.9e-26 92.4 0.0 6.5e-26 91.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY50337.1 - 1.2e-13 51.4 0.1 3.8e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KIY50337.1 - 4.3e-05 23.8 1.3 0.3 11.4 0.0 3.0 3 0 0 3 3 3 2 TrkA-N domain DAO PF01266.24 KIY50337.1 - 4.6e-05 23.2 0.0 0.045 13.3 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIY50337.1 - 0.0028 16.8 0.0 0.044 12.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIY50337.1 - 0.0032 17.5 1.0 6.8 6.7 0.0 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KIY50337.1 - 0.0062 15.7 0.0 0.12 11.5 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KIY50337.1 - 0.0066 15.7 0.0 0.045 13.0 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY50337.1 - 0.033 14.4 0.0 5.8 7.2 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 KIY50337.1 - 0.044 13.8 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 KIY50337.1 - 0.052 12.4 0.0 2.6 6.8 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase DEAD PF00270.29 KIY50338.1 - 3.6e-16 59.4 0.1 5.3e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY50338.1 - 2.4e-13 50.4 0.0 3.1e-11 43.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIY50338.1 - 6.4e-12 46.0 0.5 1.8e-11 44.5 0.5 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KIY50338.1 - 8.7e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RQC PF09382.10 KIY50338.1 - 0.0013 18.4 0.1 0.24 11.2 0.0 2.9 3 0 0 3 3 3 1 RQC domain DUF1996 PF09362.10 KIY50339.1 - 1.6e-75 254.1 2.6 2e-75 253.8 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Aminotran_1_2 PF00155.21 KIY50340.1 - 3.3e-42 145.0 0.0 3.7e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIY50340.1 - 7.5e-08 31.3 0.1 1.1e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIY50340.1 - 0.00045 19.3 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 KIY50340.1 - 0.0014 17.5 0.0 0.0038 16.1 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KIY50340.1 - 0.0018 17.6 0.9 0.0027 17.1 0.9 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KIY50340.1 - 0.0039 16.5 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase ICMT PF04140.14 KIY50341.1 - 2.6e-12 47.0 0.2 1.8e-11 44.3 0.2 2.2 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY50341.1 - 1.9e-09 37.8 0.5 4e-09 36.8 0.5 1.7 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIY50341.1 - 0.0006 18.7 0.0 0.00092 18.1 0.0 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PRIMA1 PF16101.5 KIY50341.1 - 0.29 11.2 1.2 0.54 10.3 1.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DEAD PF00270.29 KIY50342.1 - 4.3e-40 137.3 0.0 2.4e-39 134.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY50342.1 - 2.3e-24 85.9 0.2 1.6e-23 83.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KIY50342.1 - 7.5e-21 74.2 2.8 2.8e-20 72.3 2.8 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain TPR_15 PF13429.6 KIY50342.1 - 0.028 13.6 0.0 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MMPL PF03176.15 KIY50342.1 - 0.18 10.7 1.0 0.28 10.1 1.0 1.2 1 0 0 1 1 1 0 MMPL family CTP_transf_1 PF01148.20 KIY50343.1 - 2e-72 244.2 19.2 3.1e-72 243.6 19.2 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family COX7C PF02935.16 KIY50343.1 - 3.8 7.8 7.2 0.71 10.2 0.2 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc ATG27 PF09451.10 KIY50344.1 - 1.2e-62 212.2 0.0 1.3e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KIY50344.1 - 4.6e-05 22.6 0.0 7.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 KIY50344.1 - 0.12 12.4 0.0 5.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat Amidohydro_1 PF01979.20 KIY50345.1 - 1.2e-32 113.6 0.0 1.4e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIY50345.1 - 1.3e-09 38.1 0.0 1.9e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Yippee-Mis18 PF03226.14 KIY50346.1 - 1.6e-05 25.1 0.1 1.6e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 KIY50346.1 - 0.0036 17.1 0.2 0.0054 16.6 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease RIG-I_C-RD PF11648.8 KIY50346.1 - 0.08 13.2 0.1 0.11 12.7 0.1 1.3 1 1 0 1 1 1 0 C-terminal domain of RIG-I RabGAP-TBC PF00566.18 KIY50347.1 - 1.8e-52 178.1 0.0 4e-52 177.0 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cep57_CLD_2 PF14197.6 KIY50347.1 - 0.00051 20.1 9.6 0.00083 19.4 5.4 2.9 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 FPP PF05911.11 KIY50347.1 - 0.057 11.6 11.3 0.1 10.8 11.3 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 KIY50347.1 - 0.13 12.3 12.0 0.33 11.0 12.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Scaffolding_pro PF11418.8 KIY50347.1 - 0.28 11.7 3.7 11 6.6 1.7 2.7 2 0 0 2 2 2 0 Phi29 scaffolding protein TMEM247 PF15444.6 KIY50347.1 - 0.64 10.0 6.8 0.4 10.7 3.5 2.1 2 0 0 2 2 2 0 Transmembrane protein 247 YabA PF06156.13 KIY50347.1 - 1.8 9.2 8.9 9.5 6.9 8.3 2.4 2 1 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 KIY50347.1 - 4.2 7.9 14.7 0.75 10.3 10.5 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KIY50347.1 - 7.4 6.4 7.5 11 5.9 1.0 2.7 2 1 1 3 3 3 0 Septum formation initiator DASH_Duo1 PF08651.10 KIY50348.1 - 6.4e-20 70.7 0.1 1e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF2514 PF10721.9 KIY50348.1 - 0.87 9.6 17.3 0.22 11.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) LMBR1 PF04791.16 KIY50348.1 - 3.1 6.6 5.0 3.6 6.4 5.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Rrn6 PF10214.9 KIY50348.1 - 5.7 5.3 14.4 7.2 5.0 14.4 1.2 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Fe_hyd_lg_C PF02906.14 KIY50350.1 - 2e-58 197.9 0.0 5.2e-58 196.6 0.0 1.7 2 1 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain SNARE PF05739.19 KIY50352.1 - 1.8e-14 53.5 0.2 4e-14 52.3 0.2 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KIY50352.1 - 4.5e-06 26.5 0.7 3.2e-05 23.7 0.3 2.0 1 1 0 2 2 2 1 Syntaxin zf-RING_2 PF13639.6 KIY50353.1 - 9.5e-12 45.1 5.2 1.7e-11 44.2 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KIY50353.1 - 1.1e-07 31.4 1.5 1.1e-07 31.4 1.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIY50353.1 - 6e-07 29.2 4.8 1.1e-06 28.4 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY50353.1 - 3.8e-05 23.9 5.1 9.8e-05 22.6 5.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KIY50353.1 - 5.1e-05 23.1 2.7 9.1e-05 22.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY50353.1 - 5.5e-05 23.2 1.6 0.0001 22.3 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KIY50353.1 - 0.00016 21.4 2.9 0.00028 20.6 2.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KIY50353.1 - 0.00064 19.6 2.8 0.0013 18.7 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY50353.1 - 0.0048 16.7 7.2 0.097 12.6 7.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KIY50353.1 - 0.007 16.5 1.5 0.019 15.1 1.5 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KIY50353.1 - 0.0095 15.8 1.5 0.021 14.7 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KIY50353.1 - 0.052 13.7 2.8 0.11 12.7 2.8 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.6 KIY50353.1 - 0.059 13.4 4.4 0.21 11.7 1.0 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_1 PF14446.6 KIY50353.1 - 0.79 9.7 4.7 2.3 8.2 2.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ADH_zinc_N PF00107.26 KIY50354.1 - 6.4e-25 87.6 0.1 1.3e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY50354.1 - 1.2e-14 55.4 0.0 2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY50354.1 - 6.2e-07 29.3 0.0 2.8e-06 27.2 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Myb_DNA-binding PF00249.31 KIY50355.1 - 0.077 13.2 0.0 0.29 11.4 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain HECT PF00632.25 KIY50356.1 - 1.1e-91 307.6 0.0 2.7e-91 306.3 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 KIY50356.1 - 3.2e-90 302.8 0.0 3.2e-90 302.8 0.0 5.5 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KIY50356.1 - 4.2e-59 200.8 11.4 7.2e-39 134.2 1.7 4.6 3 1 1 4 4 4 2 Domain of Unknown Function (DUF908) UBM PF14377.6 KIY50356.1 - 2.2e-29 100.0 16.7 1.1e-10 40.6 0.7 4.0 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 KIY50356.1 - 4.1e-14 52.1 0.1 1.2e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_2 PF13639.6 KIY50357.1 - 1.6e-10 41.1 1.4 2.2e-08 34.3 0.3 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIY50357.1 - 2.4e-08 34.1 0.5 6.9e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIY50357.1 - 9.7e-08 31.7 3.8 6.4e-07 29.1 1.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY50357.1 - 2.3e-07 30.4 2.1 0.00013 21.6 0.0 2.9 3 0 0 3 3 3 2 RING-like zinc finger zf-C3HC4 PF00097.25 KIY50357.1 - 5e-07 29.5 1.5 5.1e-06 26.3 0.2 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY50357.1 - 9.3e-06 25.6 5.4 0.0015 18.5 0.0 3.5 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIY50357.1 - 1.4e-05 24.8 0.8 3.8e-05 23.5 0.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIY50357.1 - 9.2e-05 22.3 0.4 0.00032 20.6 0.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY50357.1 - 0.00099 18.9 1.7 0.0023 17.7 0.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY50357.1 - 0.001 19.1 2.3 0.0021 18.1 0.1 2.5 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KIY50357.1 - 0.081 12.7 0.6 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KIY50357.1 - 0.095 12.9 0.7 0.57 10.4 0.2 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 KIY50357.1 - 0.22 11.2 3.3 0.14 11.9 0.9 1.9 2 0 0 2 2 2 0 P-11 zinc finger FANCL_C PF11793.8 KIY50357.1 - 0.31 11.3 6.0 0.75 10.0 3.2 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain ASFV_J13L PF05568.11 KIY50357.1 - 0.46 10.2 0.0 0.46 10.2 0.0 2.8 4 0 0 4 4 3 0 African swine fever virus J13L protein Zn_ribbon_17 PF17120.5 KIY50357.1 - 1 9.1 3.2 0.46 10.1 0.5 1.8 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type ABC1 PF03109.16 KIY50358.1 - 2.4e-29 101.9 0.0 4e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KIY50358.1 - 0.00079 19.1 0.0 0.0054 16.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family PC4 PF02229.16 KIY50359.1 - 2.5e-22 78.2 0.3 3.3e-22 77.9 0.3 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) XisH PF08814.10 KIY50359.1 - 0.12 12.5 0.1 1 9.5 0.0 1.9 2 0 0 2 2 2 0 XisH protein Aa_trans PF01490.18 KIY50361.1 - 1.3e-69 235.0 20.8 1.5e-69 234.7 20.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GHMP_kinases_N PF00288.26 KIY50362.1 - 1.2e-14 54.2 1.3 3e-14 53.0 1.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIY50362.1 - 1.4e-05 25.3 0.0 4.7e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Ferrochelatase PF00762.19 KIY50363.1 - 1.6e-99 333.0 0.0 1.8e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase TraE PF05309.11 KIY50363.1 - 0.18 11.1 0.0 4.6 6.6 0.0 2.1 2 0 0 2 2 2 0 TraE protein Presenilin PF01080.17 KIY50365.1 - 1.2 7.8 13.4 0.31 9.8 10.3 1.6 1 1 1 2 2 2 0 Presenilin Glyco_hydro_16 PF00722.21 KIY50366.1 - 7.7e-05 22.2 0.0 0.00027 20.5 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DUF2976 PF11190.8 KIY50366.1 - 0.085 12.7 0.1 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Fur_reg_FbpB PF13040.6 KIY50367.1 - 0.55 9.8 2.3 1.2 8.7 0.3 2.2 2 0 0 2 2 2 0 Fur-regulated basic protein B Claudin_2 PF13903.6 KIY50368.1 - 0.00023 21.0 3.6 0.00032 20.5 3.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Virul_fac_BrkB PF03631.15 KIY50368.1 - 0.003 17.2 3.9 0.003 17.2 3.9 1.7 2 0 0 2 2 2 1 Virulence factor BrkB SUR7 PF06687.12 KIY50368.1 - 0.038 13.6 5.8 0.4 10.3 5.9 2.1 1 1 0 1 1 1 0 SUR7/PalI family DUF3328 PF11807.8 KIY50368.1 - 0.15 11.8 0.8 0.99 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) VirB8 PF04335.13 KIY50368.1 - 0.41 10.5 1.9 0.46 10.3 0.3 1.8 2 0 0 2 2 2 0 VirB8 protein Amastin PF07344.11 KIY50368.1 - 0.6 10.0 9.1 6.2 6.6 9.1 2.2 1 1 0 1 1 1 0 Amastin surface glycoprotein Glyco_hydro_18 PF00704.28 KIY50369.1 - 4.2e-75 253.4 0.0 5.1e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-AN1 PF01428.16 KIY50370.1 - 9.6e-19 67.3 34.4 9e-10 38.6 11.1 2.6 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KIY50370.1 - 0.0018 18.6 20.1 0.18 12.2 5.6 2.5 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Rox3 PF08633.10 KIY50370.1 - 0.13 12.5 1.1 0.18 12.1 1.1 1.2 1 0 0 1 1 1 0 Rox3 mediator complex subunit YCII PF03795.14 KIY50372.1 - 0.0017 18.7 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain BTB PF00651.31 KIY50374.1 - 9e-05 22.7 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Beta-lactamase PF00144.24 KIY50374.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase ECH_1 PF00378.20 KIY50376.1 - 2.7e-88 295.5 0.6 3e-88 295.4 0.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY50376.1 - 5e-36 124.9 1.0 7.9e-32 111.1 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KIY50376.1 - 0.0082 16.1 0.1 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family S49 DUF3813 PF12758.7 KIY50376.1 - 6.8 7.1 6.0 4.3 7.8 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) DUF4536 PF15055.6 KIY50377.1 - 1.3e-06 28.5 1.3 2e-06 27.9 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DoxX_2 PF13564.6 KIY50377.1 - 0.043 13.9 0.0 0.048 13.8 0.0 1.1 1 0 0 1 1 1 0 DoxX-like family MyTH4 PF00784.17 KIY50379.1 - 6.2e-29 100.7 0.1 1.9e-28 99.1 0.0 1.9 2 0 0 2 2 2 1 MyTH4 domain RhoGAP PF00620.27 KIY50379.1 - 4.9e-28 97.9 0.0 7.7e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 KIY50379.1 - 6.5e-10 38.9 6.4 0.00011 22.2 3.3 2.6 2 0 0 2 2 2 2 WW domain O-FucT PF10250.9 KIY50380.1 - 1.1e-10 41.7 0.2 6.1e-05 22.9 0.1 2.8 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase DUF3328 PF11807.8 KIY50380.1 - 0.054 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) SAM_2 PF07647.17 KIY50382.1 - 3.1e-05 24.0 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIY50382.1 - 0.00013 22.3 0.0 0.00017 22.0 0.0 1.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 KIY50382.1 - 0.0037 17.1 0.0 0.0044 16.8 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KIY50382.1 - 0.043 13.9 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 IGR protein motif RuvB_C PF05491.13 KIY50382.1 - 0.087 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain DUF1932 PF09130.11 KIY50383.1 - 2.6e-17 62.6 0.1 2.6e-17 62.6 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KIY50383.1 - 7.8e-05 22.9 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIY50383.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KIY50383.1 - 0.083 13.5 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ETF PF01012.21 KIY50385.1 - 1.7e-42 145.4 3.1 2.2e-42 145.0 3.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SKN1 PF03935.15 KIY50386.1 - 3.2e-169 563.5 0.9 3.8e-169 563.3 0.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GTP_EFTU PF00009.27 KIY50387.1 - 8.8e-16 58.0 0.0 2.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KIY50387.1 - 1.1e-08 35.4 1.6 1.1e-08 35.4 1.6 2.9 3 1 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KIY50387.1 - 0.00027 21.2 0.0 0.00056 20.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain RsgA_GTPase PF03193.16 KIY50387.1 - 0.1 12.5 0.3 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU_D4 PF14578.6 KIY50387.1 - 0.34 10.8 1.8 0.74 9.8 0.7 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Hydrolase_6 PF13344.6 KIY50389.1 - 2.7e-22 78.8 0.0 4.2e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY50389.1 - 2.1e-12 46.9 0.0 5.7e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like bZIP_2 PF07716.15 KIY50390.1 - 2.7e-11 43.4 17.1 3.1e-10 40.0 10.7 2.4 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KIY50390.1 - 1.8e-09 37.5 12.3 6.2e-09 35.8 8.3 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KIY50390.1 - 0.007 16.9 8.8 0.007 16.9 8.8 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF5398 PF17376.2 KIY50390.1 - 0.1 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5398) Fmp27_WPPW PF10359.9 KIY50390.1 - 0.13 11.1 0.3 0.17 10.7 0.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HAP1_N PF04849.13 KIY50390.1 - 0.14 11.3 4.9 0.11 11.7 3.5 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region TSC22 PF01166.18 KIY50390.1 - 0.14 12.4 0.8 2.2 8.7 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Spc7 PF08317.11 KIY50390.1 - 0.18 10.7 2.6 0.25 10.2 2.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FAM76 PF16046.5 KIY50390.1 - 0.18 11.1 0.5 0.27 10.5 0.5 1.1 1 0 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 KIY50390.1 - 0.3 10.9 3.5 0.46 10.3 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SOGA PF11365.8 KIY50390.1 - 1.4 10.1 5.6 0.6 11.3 2.2 2.0 2 0 0 2 2 2 0 Protein SOGA SKI PF01202.22 KIY50391.1 - 1.3e-09 38.4 0.0 3.3e-07 30.5 0.0 3.0 2 1 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 KIY50391.1 - 4e-07 30.3 0.0 1.6e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY50391.1 - 0.0011 19.5 0.1 0.0068 17.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIY50391.1 - 0.0013 19.1 0.3 0.044 14.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIY50391.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY50391.1 - 0.028 14.8 0.0 0.051 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Cytidylate_kin2 PF13189.6 KIY50391.1 - 0.028 14.6 0.2 0.084 13.0 0.0 1.7 2 1 0 2 2 2 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 KIY50391.1 - 0.065 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_25 PF13481.6 KIY50391.1 - 0.17 11.4 0.7 3.7 7.1 0.5 2.2 2 1 0 2 2 2 0 AAA domain dNK PF01712.19 KIY50391.1 - 0.17 11.7 0.0 4.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF596 PF04591.12 KIY50391.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF596 AAA_30 PF13604.6 KIY50391.1 - 0.21 11.3 0.5 0.4 10.4 0.5 1.4 1 0 0 1 1 1 0 AAA domain CHZ PF09649.10 KIY50393.1 - 3e-07 29.8 15.1 3.4e-06 26.4 15.1 2.8 1 1 0 1 1 1 1 Histone chaperone domain CHZ Pox_Ag35 PF03286.14 KIY50393.1 - 0.046 13.5 10.2 0.048 13.5 10.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 KIY50393.1 - 0.056 11.6 25.9 0.06 11.5 25.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KIY50393.1 - 0.084 12.0 19.6 0.09 11.9 19.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 KIY50393.1 - 0.1 12.6 10.6 0.16 12.0 10.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 KIY50393.1 - 0.16 11.3 13.5 0.17 11.3 13.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 KIY50393.1 - 0.21 9.9 11.5 0.2 9.9 11.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 KIY50393.1 - 0.23 9.5 9.6 0.22 9.6 9.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 KIY50393.1 - 0.31 9.2 17.1 0.29 9.3 17.1 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KIY50393.1 - 0.45 9.9 16.7 0.45 9.9 16.7 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 KIY50393.1 - 0.56 10.1 14.8 0.7 9.7 14.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RPN2_C PF18004.1 KIY50393.1 - 0.68 9.8 6.8 0.72 9.8 6.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 KIY50393.1 - 0.81 9.3 16.8 13 5.5 16.8 2.0 1 1 0 1 1 1 0 FAM176 family DUF2722 PF10846.8 KIY50393.1 - 0.86 8.5 8.3 0.85 8.5 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.10 KIY50393.1 - 0.87 8.9 18.8 0.91 8.8 18.8 1.0 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 KIY50393.1 - 0.97 9.2 8.1 1.3 8.8 8.1 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 KIY50393.1 - 1.1 8.4 9.6 1.2 8.3 9.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4637 PF15470.6 KIY50393.1 - 1.2 8.9 12.3 1.4 8.6 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NOA36 PF06524.12 KIY50393.1 - 1.4 8.2 21.1 1.7 7.9 21.1 1.1 1 0 0 1 1 1 0 NOA36 protein IFT57 PF10498.9 KIY50393.1 - 1.7 7.5 8.8 1.8 7.4 8.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RR_TM4-6 PF06459.12 KIY50393.1 - 2 8.2 7.7 2 8.1 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PI3K_1B_p101 PF10486.9 KIY50393.1 - 2.9 5.5 5.0 2.9 5.6 5.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TLP-20 PF06088.11 KIY50393.1 - 3.6 7.5 8.5 5.6 6.8 8.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4746 PF15928.5 KIY50393.1 - 3.8 6.9 11.9 4.5 6.6 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 KIY50393.1 - 5.6 5.6 6.0 5.6 5.6 6.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KIY50393.1 - 6.2 5.5 4.5 6.7 5.4 4.5 1.0 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 KIY50393.1 - 6.4 5.2 14.5 6.8 5.1 14.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.12 KIY50393.1 - 7 5.5 6.6 7.5 5.4 6.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Cwf_Cwc_15 PF04889.12 KIY50393.1 - 9.5 5.9 19.1 14 5.4 19.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ctr PF04145.15 KIY50394.1 - 3.7e-29 102.3 0.4 4.5e-29 102.0 0.4 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Proteasome PF00227.26 KIY50395.1 - 1.5e-53 181.2 0.2 2.7e-53 180.3 0.2 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY50395.1 - 1.7e-11 43.5 0.0 3.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TP6A_N PF04406.14 KIY50396.1 - 9.2e-23 80.0 0.1 1.7e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase MFS_1 PF07690.16 KIY50399.1 - 1e-34 120.0 62.5 1.3e-30 106.5 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY50399.1 - 3.1e-31 108.7 25.6 3.1e-23 82.4 9.6 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3435 PF11917.8 KIY50400.1 - 0.076 11.9 1.2 0.11 11.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) BTB PF00651.31 KIY50401.1 - 0.0022 18.2 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain GST_N PF02798.20 KIY50402.1 - 5.9e-06 26.5 0.3 6e-05 23.3 0.3 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY50402.1 - 0.00014 22.2 0.2 0.0013 19.1 0.2 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY50402.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY50402.1 - 0.038 14.2 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aminotran_1_2 PF00155.21 KIY50403.1 - 4.4e-24 85.3 0.0 5.6e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIY50403.1 - 2.3e-08 33.3 0.0 3.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Glyco_hydro_63 PF03200.16 KIY50404.1 - 1e-06 27.8 12.8 2.5e-05 23.3 0.9 4.6 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain Nup96 PF12110.8 KIY50405.1 - 7.2e-67 225.6 0.0 1.1e-66 225.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 SDA1 PF05285.12 KIY50405.1 - 7.5 5.9 20.2 14 5.0 20.2 1.4 1 0 0 1 1 1 0 SDA1 Cellulase PF00150.18 KIY50406.1 - 1.5e-13 50.8 0.5 3.7e-13 49.5 0.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CRF-BP PF05428.11 KIY50406.1 - 0.088 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Mito_carr PF00153.27 KIY50407.1 - 4.8e-35 119.4 3.8 7e-17 61.1 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KIY50407.1 - 0.13 12.5 0.0 7.2 6.9 0.0 2.6 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PXA PF02194.15 KIY50408.1 - 5.3e-46 156.9 0.0 2.1e-45 155.0 0.0 2.1 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KIY50408.1 - 2.8e-28 98.7 0.1 8.8e-28 97.1 0.1 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KIY50408.1 - 4.4e-16 58.9 0.0 3.7e-15 55.9 0.0 2.5 3 0 0 3 3 3 1 PX domain RGS PF00615.19 KIY50408.1 - 4.1e-10 40.0 0.0 1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Isy1 PF06246.12 KIY50408.1 - 0.34 10.4 0.0 0.34 10.4 0.0 1.9 3 0 0 3 3 3 0 Isy1-like splicing family ABC_tran_CTD PF16326.5 KIY50408.1 - 1.1 9.6 5.0 0.83 10.0 1.5 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Gcd10p PF04189.13 KIY50409.1 - 4.1e-66 223.1 0.0 6.3e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family FTO_NTD PF12933.7 KIY50409.1 - 0.015 14.6 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 FTO catalytic domain PP1c_bdg PF10488.9 KIY50409.1 - 0.15 11.5 0.8 14 5.0 0.0 2.1 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region DUF148 PF02520.17 KIY50410.1 - 0.04 14.0 0.3 0.077 13.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 Transcrip_act PF04949.13 KIY50410.1 - 0.33 10.8 3.4 0.66 9.9 3.4 1.4 1 0 0 1 1 1 0 Transcriptional activator Lum_binding PF00677.17 KIY50411.1 - 2.9e-45 152.2 0.3 1.2e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain UNC45-central PF11701.8 KIY50412.1 - 1.7e-28 99.5 0.0 3.7e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KIY50412.1 - 1 9.5 5.8 3 8.0 0.1 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Myosin_head PF00063.21 KIY50413.1 - 2.4e-238 792.8 0.0 2.9e-238 792.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KIY50413.1 - 4.7e-49 166.6 0.3 1.1e-48 165.4 0.0 1.8 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KIY50413.1 - 4.3e-10 39.0 0.7 8.9e-10 38.0 0.7 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY50413.1 - 5.7e-08 32.5 0.1 1.3e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY50413.1 - 1.3e-06 28.0 0.0 3.8e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KIY50413.1 - 0.0001 22.5 0.2 0.00028 21.1 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Hpr_kinase_C PF07475.12 KIY50413.1 - 0.056 13.0 1.1 7.9 6.0 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 KIY50413.1 - 0.071 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIY50413.1 - 0.073 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIY50413.1 - 0.11 12.6 0.1 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIY50413.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 KIY50413.1 - 0.16 11.7 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KIY50413.1 - 0.17 12.3 0.2 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase zf-RING_2 PF13639.6 KIY50416.1 - 3.5e-11 43.3 5.5 5.2e-11 42.7 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KIY50416.1 - 2.4e-10 40.5 4.1 4.1e-10 39.8 4.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIY50416.1 - 9.9e-08 31.7 7.4 3e-07 30.2 7.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY50416.1 - 2.9e-07 30.2 4.6 4.4e-07 29.7 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY50416.1 - 2.3e-06 27.5 5.5 4.4e-06 26.6 5.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KIY50416.1 - 2.9e-06 26.9 3.2 7.5e-06 25.6 3.2 1.7 1 1 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KIY50416.1 - 5.8e-06 26.2 2.2 8.5e-06 25.6 2.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIY50416.1 - 2.5e-05 24.3 0.5 4.6e-05 23.4 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KIY50416.1 - 0.00064 19.5 2.5 0.0011 18.7 2.5 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KIY50416.1 - 0.1 12.8 3.6 0.39 10.9 3.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KIY50416.1 - 0.14 11.8 2.0 0.31 10.7 2.0 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KIY50416.1 - 0.14 12.1 2.2 0.24 11.3 2.2 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 KIY50416.1 - 0.15 12.0 5.4 0.26 11.2 5.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Auto_anti-p27 PF06677.12 KIY50416.1 - 1.2 9.3 3.5 10 6.3 0.0 2.7 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Prok-RING_1 PF14446.6 KIY50416.1 - 2.2 8.3 6.5 1.9 8.4 4.1 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 ABC_membrane PF00664.23 KIY50417.1 - 7e-50 170.2 17.1 2.7e-33 115.8 5.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY50417.1 - 6.9e-26 91.4 0.0 5.1e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY50417.1 - 4.9e-11 42.5 0.1 0.00023 20.7 0.0 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY50417.1 - 0.0019 18.8 0.1 0.003 18.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY50417.1 - 0.0051 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 KIY50417.1 - 0.0051 15.9 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KIY50417.1 - 0.016 15.6 0.1 0.098 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KIY50417.1 - 0.069 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin ISK_Channel PF02060.15 KIY50417.1 - 0.084 12.6 1.1 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 Slow voltage-gated potassium channel RsgA_GTPase PF03193.16 KIY50417.1 - 0.091 12.7 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KIY50417.1 - 0.17 11.4 1.6 1.2 8.6 1.6 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIY50417.1 - 0.18 12.2 0.0 2.1 8.8 0.0 2.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 KIY50417.1 - 0.19 10.5 0.1 0.32 9.8 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_22 PF13401.6 KIY50417.1 - 0.19 12.0 0.1 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KIY50417.1 - 1.8 8.3 8.5 4.4 7.0 0.5 3.5 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF89 PF01937.19 KIY50418.1 - 3.2e-106 355.3 0.2 4e-106 354.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Spc7 PF08317.11 KIY50419.1 - 9.3e-05 21.5 11.0 9.3e-05 21.5 11.0 10.2 2 2 10 12 12 12 4 Spc7 kinetochore protein GAS PF13851.6 KIY50419.1 - 0.0002 20.8 9.3 0.0002 20.8 9.3 11.7 4 4 5 11 11 11 4 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 KIY50419.1 - 0.0023 18.2 0.9 0.0023 18.2 0.9 13.6 4 3 11 16 16 16 1 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KIY50419.1 - 0.0024 18.4 7.8 0.0024 18.4 7.8 14.1 1 1 12 14 14 14 3 Apg6 coiled-coil region UPA_2 PF17809.1 KIY50419.1 - 0.05 13.4 0.1 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 UPA domain DUF4988 PF16378.5 KIY50419.1 - 0.36 10.5 5.4 9.2 5.9 0.2 4.7 3 1 0 3 3 3 0 Domain of unknown function HSBP1 PF06825.12 KIY50419.1 - 1.1 9.2 20.7 2.3 8.2 0.2 6.4 5 1 1 6 6 6 0 Heat shock factor binding protein 1 Fez1 PF06818.15 KIY50419.1 - 3.1 8.2 181.9 0.81 10.1 17.1 10.0 2 2 8 10 10 10 0 Fez1 Lgl_C PF08596.10 KIY50420.1 - 1.5e-44 152.3 0.0 4.8e-44 150.6 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 KIY50420.1 - 7.7e-05 22.9 0.0 0.11 12.7 0.0 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY50420.1 - 0.017 16.0 2.4 0.14 13.0 0.1 3.7 5 0 0 5 5 5 0 WD domain, G-beta repeat p450 PF00067.22 KIY50421.1 - 1e-48 166.3 0.0 1.4e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.16 KIY50424.1 - 5.1e-48 164.2 0.0 6.4e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_47 PF01532.20 KIY50426.1 - 3.4e-151 504.2 0.0 3.9e-151 504.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Mito_carr PF00153.27 KIY50427.1 - 4.5e-60 199.6 0.4 3.5e-21 74.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KIY50427.1 - 1.7e-17 61.6 1.1 8.4e-07 28.1 0.0 6.1 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 KIY50427.1 - 2.7e-17 63.0 4.5 1.1e-05 25.7 0.0 4.3 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KIY50427.1 - 9.4e-15 53.2 3.3 2.7e-05 23.8 0.1 6.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 KIY50427.1 - 3e-10 39.8 1.2 0.023 14.5 0.1 4.7 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KIY50427.1 - 2e-08 33.3 2.9 0.00025 20.4 0.0 4.2 4 0 0 4 4 4 2 EF hand Met_10 PF02475.16 KIY50428.1 - 7.3e-68 228.2 0.0 9.6e-68 227.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 KIY50428.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 KIY50428.1 - 0.012 15.2 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.16 KIY50428.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.7 KIY50428.1 - 0.027 14.4 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TauD PF02668.16 KIY50429.1 - 9.9e-56 189.5 0.1 1.2e-55 189.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TatD_DNase PF01026.21 KIY50430.1 - 1.4e-24 86.9 0.3 1.8e-24 86.5 0.3 1.1 1 0 0 1 1 1 1 TatD related DNase V-SNARE_C PF12352.8 KIY50431.1 - 1.4e-16 60.5 2.0 4.4e-16 58.9 0.9 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Filament PF00038.21 KIY50431.1 - 0.0039 16.8 2.0 0.0039 16.8 2.0 1.5 1 1 0 1 1 1 1 Intermediate filament protein Med30 PF11315.8 KIY50431.1 - 0.0055 16.9 1.6 0.011 15.9 0.1 2.1 2 1 0 2 2 2 1 Mediator complex subunit 30 DNA_photolyase PF00875.18 KIY50431.1 - 0.024 14.6 0.2 0.034 14.2 0.2 1.3 1 0 0 1 1 1 0 DNA photolyase kleA_kleC PF17383.2 KIY50431.1 - 0.026 14.8 0.3 0.068 13.5 0.3 1.7 1 1 0 1 1 1 0 Uncharacterized KorC regulated protein A AbiH PF14253.6 KIY50431.1 - 0.097 12.5 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Baculo_PEP_C PF04513.12 KIY50431.1 - 0.16 12.0 7.2 2.6 8.1 1.7 2.5 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KIY50431.1 - 0.17 12.0 1.3 5.6 7.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BST2 PF16716.5 KIY50431.1 - 0.17 12.5 8.3 0.3 11.7 0.3 2.7 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 CCDC-167 PF15188.6 KIY50431.1 - 0.96 9.8 4.3 0.55 10.6 0.2 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Acyl-CoA_dh_1 PF00441.24 KIY50432.1 - 0.011 15.9 0.7 0.024 14.9 0.7 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain TetR_C_8 PF14278.6 KIY50432.1 - 0.15 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region MFS_1 PF07690.16 KIY50433.1 - 4.8e-23 81.7 69.3 5.3e-17 61.8 41.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF829 PF05705.14 KIY50435.1 - 4.9e-37 128.1 0.0 6.1e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) adh_short PF00106.25 KIY50436.1 - 9.5e-47 159.0 1.0 1.2e-46 158.7 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY50436.1 - 4.2e-31 108.3 0.5 5e-31 108.1 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY50436.1 - 5.4e-08 33.0 0.0 8.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY50436.1 - 1.9e-07 30.8 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIY50436.1 - 4.2e-07 29.7 0.0 1.1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY50436.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KIY50437.1 - 1.2e-26 93.4 0.1 2e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY50437.1 - 0.0011 19.0 10.9 0.0033 17.5 10.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIPSNAP PF07978.13 KIY50438.1 - 2e-29 101.8 6.6 1.1e-23 83.3 2.0 2.2 2 0 0 2 2 2 2 NIPSNAP Fructosamin_kin PF03881.14 KIY50439.1 - 2.1e-64 217.5 0.0 2.5e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KIY50439.1 - 2.9e-09 37.2 0.0 4.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Aminotran_4 PF01063.19 KIY50440.1 - 1.2e-30 107.1 0.0 1.5e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV WD40 PF00400.32 KIY50441.1 - 5.1e-58 191.7 25.4 1.6e-05 25.5 0.1 11.4 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 KIY50441.1 - 5.4e-48 162.5 0.0 8.6e-48 161.9 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KIY50441.1 - 1.5e-13 50.9 0.6 3.3 8.1 0.0 8.4 6 2 3 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY50441.1 - 2.7e-06 26.3 3.3 1.2 7.7 0.1 5.5 4 2 1 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY50441.1 - 0.00053 19.4 0.0 0.02 14.2 0.0 3.4 5 0 0 5 5 5 1 WD40-like domain Mcl1_mid PF12341.8 KIY50441.1 - 0.0085 15.5 0.1 2.6 7.3 0.0 2.7 2 0 0 2 2 2 2 Minichromosome loss protein, Mcl1, middle region Nucleoporin_N PF08801.11 KIY50441.1 - 0.01 14.6 4.9 12 4.6 1.3 5.2 1 1 4 5 5 5 0 Nup133 N terminal like VID27 PF08553.10 KIY50441.1 - 0.027 13.5 0.0 0.83 8.6 0.0 2.9 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 KIY50441.1 - 0.071 11.6 0.6 2.5 6.5 0.0 3.0 4 0 0 4 4 4 0 Cytochrome D1 heme domain Mod_r PF07200.13 KIY50442.1 - 0.18 11.9 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein MBOAT_2 PF13813.6 KIY50443.1 - 8.2e-08 32.4 4.2 8.2e-08 32.4 4.2 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family EHN PF06441.12 KIY50444.1 - 2.7e-32 111.3 0.4 1.3e-31 109.1 0.0 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIY50444.1 - 1.2e-14 54.6 0.0 1.7e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY50444.1 - 0.00013 22.7 1.2 0.00013 22.7 1.2 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family N_BRCA1_IG PF16158.5 KIY50445.1 - 2.1e-28 99.0 0.1 6.3e-28 97.5 0.1 1.9 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KIY50445.1 - 4.9e-18 64.7 50.4 1.4e-08 34.4 5.7 4.5 4 1 1 5 5 5 3 Zinc finger, ZZ type C1_2 PF03107.16 KIY50445.1 - 2.3e-06 27.8 49.4 0.0042 17.4 5.6 4.8 5 0 0 5 5 5 4 C1 domain NFACT-C PF11923.8 KIY50446.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NFACT protein C-terminal domain DUF4596 PF15363.6 KIY50446.1 - 1.5 9.1 6.3 3.2 8.1 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Cu_amine_oxid PF01179.20 KIY50447.1 - 2e-149 498.0 0.0 2.5e-149 497.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KIY50447.1 - 1.4e-11 44.7 0.0 3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KIY50447.1 - 1.1e-05 25.6 0.0 2.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain BTB_2 PF02214.22 KIY50449.1 - 9.5e-05 22.7 0.1 0.0026 18.1 0.0 2.7 2 1 1 3 3 3 1 BTB/POZ domain Chitin_synth_2 PF03142.15 KIY50450.1 - 8.3e-280 928.9 0.0 1.1e-279 928.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY50450.1 - 8.3e-11 42.2 0.4 2.3e-10 40.7 0.4 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIY50450.1 - 2.6e-08 34.0 0.2 6.5e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIY50450.1 - 0.00018 21.0 0.1 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KIY50450.1 - 0.0045 16.8 0.0 0.066 13.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Neprosin PF03080.15 KIY50450.1 - 0.0073 15.7 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Neprosin SNAP PF14938.6 KIY50453.1 - 8.9e-108 360.0 19.0 1e-107 359.8 19.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KIY50453.1 - 2.6e-05 24.4 14.0 0.00056 20.1 4.2 3.5 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY50453.1 - 0.00044 20.1 6.8 0.065 13.3 0.4 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY50453.1 - 0.009 15.7 5.3 0.16 11.7 0.5 3.6 3 0 0 3 3 3 1 TPR repeat Clathrin PF00637.20 KIY50453.1 - 0.011 15.7 2.2 0.021 14.7 1.0 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS Glyco_hydro_4C PF11975.8 KIY50453.1 - 0.02 15.0 0.9 0.033 14.3 0.3 1.6 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain PspA_IM30 PF04012.12 KIY50453.1 - 0.054 13.1 6.2 0.28 10.7 4.2 2.3 1 1 1 2 2 2 0 PspA/IM30 family NSF PF02071.20 KIY50453.1 - 0.06 14.1 10.9 3 9.0 0.0 5.5 5 0 0 5 5 4 0 Aromatic-di-Alanine (AdAR) repeat Spatacsin_C PF14649.6 KIY50453.1 - 0.12 11.4 5.5 0.2 10.7 0.8 2.5 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_8 PF13181.6 KIY50453.1 - 0.23 11.8 8.1 22 5.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY50453.1 - 0.95 9.7 16.0 0.94 9.8 1.1 5.1 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY50453.1 - 1.3 9.8 11.9 12 6.8 0.1 5.5 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY50453.1 - 2 9.2 8.5 2.5 8.8 0.4 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIY50453.1 - 8.2 6.5 9.5 2.2 8.3 0.1 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat PGM_PMM_I PF02878.16 KIY50454.1 - 5.6e-17 61.7 0.1 5.1e-07 29.5 0.0 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KIY50454.1 - 7.7e-12 45.2 0.3 2.3e-11 43.7 0.3 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KIY50454.1 - 0.0024 18.5 0.1 0.056 14.1 0.1 2.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KIY50454.1 - 0.03 14.5 0.3 0.072 13.3 0.3 1.7 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF4349 PF14257.6 KIY50454.1 - 0.17 11.3 0.0 2.9 7.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) GATase_4 PF13230.6 KIY50455.1 - 7.2e-20 71.0 0.1 3.8e-19 68.6 0.1 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KIY50455.1 - 3.2e-08 33.8 0.0 6.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain RsgI_N PF12791.7 KIY50455.1 - 0.14 12.1 0.4 0.25 11.3 0.4 1.4 1 0 0 1 1 1 0 Anti-sigma factor N-terminus DUF1241 PF06840.11 KIY50456.1 - 0.0041 16.8 0.2 0.0075 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Adaptin_N PF01602.20 KIY50457.1 - 4.8e-98 329.0 0.2 6.2e-98 328.6 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIY50457.1 - 1.1e-11 45.0 0.7 1.2e-07 31.9 0.0 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY50457.1 - 4.1e-07 30.3 1.8 0.017 15.5 0.0 4.8 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 KIY50457.1 - 1.4e-06 28.0 9.3 2 8.9 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KIY50457.1 - 1.1e-05 25.8 3.4 0.063 13.8 0.0 5.4 6 1 1 7 7 7 1 HEAT-like repeat RasGEF_N_2 PF14663.6 KIY50457.1 - 0.012 16.0 1.0 0.44 11.0 0.0 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Nipped-B_C PF12830.7 KIY50457.1 - 0.036 14.0 0.2 1.3 9.0 0.0 3.2 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus RTP1_C1 PF10363.9 KIY50457.1 - 0.041 14.1 1.0 3.1 8.0 0.0 3.3 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Rep_fac-A_C PF08646.10 KIY50457.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain FerA PF08165.11 KIY50457.1 - 0.088 12.8 0.5 7.7 6.5 0.2 2.9 2 0 0 2 2 2 0 FerA (NUC095) domain Sel1 PF08238.12 KIY50458.1 - 1.2e-45 152.9 20.8 1.9e-08 34.7 0.2 7.9 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 KIY50458.1 - 5 8.0 9.5 40 5.2 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Mito_carr PF00153.27 KIY50459.1 - 2.6e-66 219.6 4.7 1.9e-23 82.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PINIT PF14324.6 KIY50460.1 - 6.7e-40 136.8 1.2 1.1e-39 136.1 1.2 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KIY50460.1 - 9.2e-17 60.5 5.9 1.6e-16 59.7 5.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KIY50460.1 - 4.3e-09 36.0 1.9 1e-08 34.9 1.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KIY50460.1 - 0.014 15.2 0.0 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 SAP domain Rad50_zn_hook PF04423.14 KIY50460.1 - 0.086 12.7 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_2 PF13923.6 KIY50460.1 - 5.1 7.0 6.3 11 5.9 6.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kinase-like PF14531.6 KIY50461.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribo_biogen_C PF04034.13 KIY50462.1 - 2.9e-51 172.5 0.0 3.9e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KIY50462.1 - 1.6e-14 53.5 0.1 3.1e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Pex16 PF08610.10 KIY50463.1 - 6.7e-102 341.0 2.3 7.5e-102 340.8 2.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) IlvN PF07991.12 KIY50464.1 - 1.6e-48 164.4 0.0 2.4e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KIY50464.1 - 3.7e-24 85.7 0.2 5.5e-24 85.1 0.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KIY50464.1 - 2.7e-08 34.3 0.0 5.9e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIY50464.1 - 9.2e-05 22.7 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KIY50464.1 - 0.00029 20.3 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY50464.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KIY50464.1 - 0.02 14.9 0.1 1 9.3 0.0 2.7 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short_C2 PF13561.6 KIY50465.1 - 9.1e-57 192.3 0.2 1.1e-56 192.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY50465.1 - 1.3e-40 139.0 0.5 1.7e-40 138.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY50465.1 - 4.4e-10 39.8 0.1 6.7e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 KR domain RRM_1 PF00076.22 KIY50466.1 - 2.1e-43 146.0 0.2 6.3e-22 77.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KIY50466.1 - 2.2e-14 54.3 0.8 7.6e-13 49.4 0.8 2.5 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KIY50466.1 - 4.2e-06 26.7 0.1 0.0014 18.6 0.0 2.8 2 1 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 KIY50466.1 - 0.0006 19.8 0.1 4.6 7.3 0.1 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KIY50466.1 - 0.00062 19.6 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KIY50466.1 - 0.035 13.7 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cys_Met_Meta_PP PF01053.20 KIY50467.1 - 1.3e-27 96.3 0.0 2.1e-27 95.7 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Rnk_N PF14760.6 KIY50467.1 - 0.2 12.2 1.1 25 5.4 0.2 2.7 2 0 0 2 2 2 0 Rnk N-terminus Solute_trans_a PF03619.16 KIY50468.1 - 6.2e-94 314.4 12.0 7.2e-94 314.2 12.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha UCH PF00443.29 KIY50469.1 - 2.7e-39 135.2 0.0 6.3e-39 134.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KIY50469.1 - 2.6e-17 62.5 0.2 6.1e-16 58.1 0.2 2.9 3 0 0 3 3 3 1 A repeated domain in UCH-protein UCH_1 PF13423.6 KIY50469.1 - 6.2e-07 29.3 0.6 0.023 14.3 0.0 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 KIY50469.1 - 0.0023 17.8 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 PUB domain APG6_N PF17675.1 KIY50469.1 - 0.026 15.1 0.6 0.026 15.1 0.6 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KIY50469.1 - 0.82 9.5 6.7 0.35 10.7 1.5 2.4 2 0 0 2 2 2 0 Septum formation initiator PRCC PF10253.9 KIY50469.1 - 6.8 7.4 9.6 4.5 8.0 3.3 2.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting MAP65_ASE1 PF03999.12 KIY50469.1 - 7.6 5.1 6.8 5.8 5.5 0.1 2.5 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) AF-4 PF05110.13 KIY50469.1 - 9.4 4.2 17.0 0.16 10.0 9.8 1.5 2 0 0 2 2 2 0 AF-4 proto-oncoprotein ADH_zinc_N PF00107.26 KIY50470.1 - 1.8e-28 99.1 0.0 2.6e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY50470.1 - 1.6e-18 68.0 0.0 2.9e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY50470.1 - 0.00048 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KIY50470.1 - 0.023 14.9 0.1 0.054 13.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain ADH_N_2 PF16884.5 KIY50470.1 - 0.041 13.8 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase NAD_binding_10 PF13460.6 KIY50470.1 - 0.098 12.5 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DHHC PF01529.20 KIY50472.1 - 2e-26 92.7 8.3 2e-26 92.7 8.3 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase F-box-like PF12937.7 KIY50473.1 - 2.4e-06 27.3 0.4 6.5e-06 26.0 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY50473.1 - 5.9e-06 26.0 1.2 1.7e-05 24.6 1.2 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY50473.1 - 0.12 12.3 0.2 0.32 10.9 0.2 1.7 1 0 0 1 1 1 0 F-box ING PF12998.7 KIY50474.1 - 2.1e-11 44.3 0.0 3.1e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIY50474.1 - 0.00035 20.4 10.4 0.00035 20.4 10.4 1.8 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 KIY50474.1 - 0.0049 17.1 2.6 0.011 16.0 2.6 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KIY50474.1 - 0.076 12.6 3.0 0.14 11.8 3.0 1.5 1 0 0 1 1 1 0 PHD-finger QWRF PF04484.12 KIY50474.1 - 2.5 7.8 7.5 0.24 11.1 3.2 1.6 2 0 0 2 2 2 0 QWRF family RabGAP-TBC PF00566.18 KIY50475.1 - 8.5e-48 162.8 0.1 1.1e-47 162.5 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box PF00646.33 KIY50476.1 - 0.071 13.0 1.5 0.16 11.9 0.0 2.3 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIY50476.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like NAD_binding_1 PF00175.21 KIY50477.1 - 5.6e-25 88.1 0.0 8.3e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIY50477.1 - 2.9e-18 66.1 0.0 5.1e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIY50477.1 - 4.5e-07 30.1 0.0 8.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Pkinase PF00069.25 KIY50478.1 - 1.9e-66 224.1 0.0 2.4e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50478.1 - 4e-32 111.5 0.0 5.3e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY50478.1 - 1.1e-05 24.6 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY50478.1 - 0.00071 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY50478.1 - 0.0017 17.7 0.1 0.004 16.5 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY50478.1 - 0.0071 15.7 0.0 0.025 13.9 0.1 1.8 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KIY50478.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KIY50478.1 - 0.029 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Abhydrolase_3 PF07859.13 KIY50479.1 - 7.2e-29 101.2 0.0 2.6e-19 69.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY50479.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase UCH PF00443.29 KIY50480.1 - 1.5e-53 181.9 0.0 1.9e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY50480.1 - 2.6e-28 99.6 0.1 6.6e-20 71.9 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KIY50480.1 - 0.062 12.8 2.9 0.26 10.7 1.6 2.5 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Glyco_hydro_63 PF03200.16 KIY50480.1 - 0.12 11.1 0.1 3.6 6.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 C-terminal domain efThoc1 PF11957.8 KIY50481.1 - 1.4e-88 297.8 1.5 2.7e-84 283.6 0.4 2.2 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor GDP_Man_Dehyd PF16363.5 KIY50481.1 - 1.2e-36 126.8 0.0 2.7e-36 125.6 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIY50481.1 - 1.9e-30 106.1 0.0 3.5e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY50481.1 - 9.2e-06 24.9 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KIY50481.1 - 1.2e-05 24.4 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KIY50481.1 - 0.00047 19.4 0.0 0.00099 18.3 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KIY50481.1 - 0.0027 17.6 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain PBP_N PF17093.5 KIY50481.1 - 0.034 14.4 2.6 0.95 9.7 2.0 2.5 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Macoilin PF09726.9 KIY50481.1 - 4 5.9 6.6 7.3 5.0 6.6 1.3 1 0 0 1 1 1 0 Macoilin family IBN_N PF03810.19 KIY50482.1 - 0.00015 21.6 0.1 0.0057 16.5 0.0 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KIY50482.1 - 0.00038 20.5 0.6 0.0034 17.5 0.1 2.9 2 1 0 2 2 2 1 Exportin 1-like protein Adaptin_N PF01602.20 KIY50482.1 - 0.00074 18.2 0.1 0.0034 16.0 0.0 2.1 2 1 0 2 2 2 1 Adaptin N terminal region CAS_CSE1 PF03378.15 KIY50482.1 - 0.0063 15.0 0.0 0.031 12.8 0.0 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus HEAT_2 PF13646.6 KIY50482.1 - 0.0082 16.5 3.0 0.25 11.8 0.0 4.2 3 1 0 3 3 3 1 HEAT repeats Cse1 PF08506.10 KIY50482.1 - 0.01 14.7 0.0 0.029 13.2 0.0 1.7 1 1 0 1 1 1 0 Cse1 ParcG PF10274.9 KIY50482.1 - 0.081 13.0 0.2 14 5.7 0.0 3.4 4 0 0 4 4 4 0 Parkin co-regulated protein HEAT PF02985.22 KIY50482.1 - 0.18 12.2 3.3 4 8.0 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat ATP-synt_E PF05680.12 KIY50485.1 - 1e-17 64.2 0.1 1.1e-17 64.1 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain Dor1 PF04124.12 KIY50487.1 - 1.3e-44 152.2 0.2 1.7e-44 151.9 0.2 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 KIY50487.1 - 0.017 15.2 0.2 0.049 13.7 0.2 1.7 1 0 0 1 1 1 0 Vps51/Vps67 COG5 PF10392.9 KIY50487.1 - 0.037 14.2 2.3 0.12 12.5 1.0 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Sec5 PF15469.6 KIY50487.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec5 PPR PF01535.20 KIY50487.1 - 0.065 13.5 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 PPR repeat Baculo_PEP_C PF04513.12 KIY50487.1 - 5.7 7.0 6.4 2.3 8.2 1.0 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box-like PF12937.7 KIY50488.1 - 1.3e-05 25.0 0.5 1.3e-05 25.0 0.5 2.1 2 0 0 2 2 2 1 F-box-like CAF1C_H4-bd PF12265.8 KIY50489.1 - 6.9e-29 99.9 0.5 1.5e-28 98.8 0.5 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KIY50489.1 - 6e-20 71.2 10.1 1.9e-05 25.3 0.1 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY50489.1 - 6.8e-05 23.1 0.0 0.022 15.0 0.0 3.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIY50489.1 - 0.00056 18.4 0.0 0.0008 17.8 0.0 1.1 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz RAMP4 PF06624.12 KIY50490.1 - 1.4e-19 69.9 0.2 1.5e-19 69.8 0.2 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DotU PF09850.9 KIY50490.1 - 0.0057 16.4 0.0 0.0068 16.2 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU CrgA PF06781.12 KIY50490.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Cell division protein CrgA DUF2431 PF10354.9 KIY50491.1 - 4.6e-47 160.4 0.0 6e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Proteasome PF00227.26 KIY50492.1 - 4.3e-55 186.2 0.0 5.4e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY50492.1 - 5.9e-14 51.4 0.0 1.3e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fip1 PF05182.13 KIY50494.1 - 2.7e-20 71.6 0.8 4.4e-20 70.9 0.8 1.3 1 0 0 1 1 1 1 Fip1 motif Ribosomal_S15 PF00312.22 KIY50495.1 - 1.7e-21 76.2 0.8 3.4e-21 75.2 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 NGP1NT PF08153.12 KIY50496.1 - 2.4e-51 173.3 0.0 5e-51 172.2 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KIY50496.1 - 1.7e-18 66.8 0.1 2.2e-14 53.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY50496.1 - 9e-06 25.3 0.5 9.2e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIY50496.1 - 2.1e-05 24.5 0.0 5.3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KIY50496.1 - 0.00051 19.6 2.8 0.053 13.1 0.1 3.3 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KIY50496.1 - 0.0054 16.2 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KIY50496.1 - 0.009 16.1 0.8 2.5 8.1 0.1 3.7 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 KIY50496.1 - 0.016 15.4 0.1 5.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NOG1 PF06858.14 KIY50496.1 - 0.11 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Enolase_C PF00113.22 KIY50497.1 - 5.1e-145 482.3 0.0 7e-145 481.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KIY50497.1 - 5.8e-59 198.0 0.1 1e-58 197.2 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KIY50497.1 - 2.5e-08 33.8 0.0 4.3e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KIY50497.1 - 0.00087 18.5 0.3 0.0022 17.2 0.3 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Raptor_N PF14538.6 KIY50498.1 - 1e-61 207.2 0.0 1.9e-61 206.3 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 KIY50498.1 - 3.8e-05 23.6 0.2 0.0017 18.5 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat WD40 PF00400.32 KIY50498.1 - 5.3e-05 23.9 12.7 0.038 14.9 0.3 6.6 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KIY50498.1 - 0.0003 21.1 0.0 0.0015 18.8 0.0 2.2 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 KIY50498.1 - 0.0079 16.7 0.1 0.034 14.7 0.1 2.2 1 0 0 1 1 1 1 HEAT-like repeat Cnd1 PF12717.7 KIY50498.1 - 0.016 15.3 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 KIY50498.1 - 0.17 12.2 1.0 1.1e+02 3.3 0.1 3.6 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PfkB PF00294.24 KIY50499.1 - 2.5e-64 217.5 0.2 3e-64 217.2 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Cellulase PF00150.18 KIY50501.1 - 5.4e-10 39.2 0.0 1.1e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RCC1 PF00415.18 KIY50502.1 - 7.2e-27 93.8 15.8 3.7e-06 27.5 0.0 7.1 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY50502.1 - 7.1e-23 79.9 15.0 7.1e-06 25.7 0.3 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Swi5 PF07061.11 KIY50503.1 - 7.6e-21 74.0 1.5 9.5e-21 73.7 1.5 1.0 1 0 0 1 1 1 1 Swi5 Macoilin PF09726.9 KIY50503.1 - 0.0018 16.9 0.3 0.002 16.8 0.3 1.0 1 0 0 1 1 1 1 Macoilin family DUF3942 PF13078.6 KIY50503.1 - 0.071 13.4 0.2 0.077 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) Cep57_CLD_2 PF14197.6 KIY50503.1 - 0.22 11.6 3.4 2.5 8.2 0.7 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 HALZ PF02183.18 KIY50503.1 - 0.86 9.9 4.6 7.3 6.9 0.3 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper Dynactin PF12455.8 KIY50506.1 - 7.3e-90 301.1 1.4 7.3e-90 301.1 1.4 3.5 4 2 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KIY50506.1 - 2.1e-21 75.7 0.2 6.2e-21 74.2 0.1 1.8 2 0 0 2 2 2 1 CAP-Gly domain Mycoplasma_p37 PF06646.11 KIY50506.1 - 3 7.0 5.4 0.46 9.7 0.4 1.9 2 0 0 2 2 2 0 High affinity transport system protein p37 CorA PF01544.18 KIY50507.1 - 1.7e-32 112.9 1.1 2.1e-30 106.0 0.5 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Pyridox_oxase_2 PF12766.7 KIY50508.1 - 7.1e-23 81.1 0.1 1.1e-22 80.5 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KIY50508.1 - 0.00018 21.6 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Nop14 PF04147.12 KIY50509.1 - 0.13 10.5 14.4 0.13 10.5 14.4 1.0 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 KIY50509.1 - 0.14 11.9 5.1 0.19 11.4 5.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH BUD22 PF09073.10 KIY50509.1 - 0.61 9.4 16.4 0.66 9.2 16.4 1.0 1 0 0 1 1 1 0 BUD22 DUF1325 PF07039.11 KIY50509.1 - 0.77 9.8 6.7 1.3 9.1 6.7 1.4 1 1 0 1 1 1 0 SGF29 tudor-like domain SDA1 PF05285.12 KIY50509.1 - 0.8 9.1 15.7 0.84 9.0 15.7 1.0 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.6 KIY50509.1 - 0.93 9.7 20.9 2.6 8.3 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 KIY50509.1 - 1.6 6.9 12.2 1.7 6.8 12.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KIY50509.1 - 1.8 6.6 18.6 2.1 6.4 18.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Usp PF00582.26 KIY50509.1 - 2.2 8.8 5.8 2.8 8.4 5.8 1.3 1 0 0 1 1 1 0 Universal stress protein family CPSF100_C PF13299.6 KIY50509.1 - 4 7.6 8.2 4.5 7.4 7.7 1.3 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ANAPC15 PF15243.6 KIY50509.1 - 6.3 7.3 23.5 19 5.7 0.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Presenilin PF01080.17 KIY50509.1 - 6.6 5.4 5.3 7.1 5.3 5.3 1.0 1 0 0 1 1 1 0 Presenilin Na_trans_assoc PF06512.13 KIY50509.1 - 6.7 6.9 14.1 8.1 6.7 14.1 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Spt4 PF06093.13 KIY50510.1 - 3.4e-31 107.2 0.1 4.2e-31 106.9 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Peptidase_M24 PF00557.24 KIY50511.1 - 4.6e-57 193.1 0.0 5.8e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KIY50511.1 - 9.9e-31 106.0 0.0 1.7e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Pkinase PF00069.25 KIY50513.1 - 3.2e-64 216.8 0.0 3.8e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50513.1 - 8.4e-30 103.9 0.0 1.1e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY50513.1 - 1.6e-05 24.3 0.1 0.00013 21.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY50513.1 - 0.00017 21.6 0.7 0.41 10.5 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_C PF00433.24 KIY50513.1 - 0.00029 21.5 0.4 0.00059 20.5 0.4 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KIY50513.1 - 0.00031 20.5 0.0 0.083 12.5 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY50513.1 - 0.0022 17.4 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY50513.1 - 0.0026 16.6 0.0 0.0052 15.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Hs1pro-1_C PF07014.12 KIY50513.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Proteasome PF00227.26 KIY50514.1 - 4.2e-38 130.8 0.0 4.8e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 KIY50514.1 - 0.047 13.8 0.0 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Phage late-transcription coactivator OPT PF03169.15 KIY50516.1 - 2.9e-137 458.9 44.0 3.3e-137 458.7 44.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1440 PF07274.12 KIY50516.1 - 1.9 8.8 7.2 2.1 8.7 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1440) UPF0203 PF05254.12 KIY50518.1 - 2.4e-25 88.6 2.2 3.1e-25 88.2 2.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 KIY50518.1 - 0.0051 17.0 3.1 0.98 9.7 0.5 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 KIY50518.1 - 0.013 15.8 2.1 1.2 9.4 0.5 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KIY50518.1 - 0.027 14.8 0.7 1.7 9.1 0.2 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 KIY50518.1 - 0.51 10.5 6.6 0.25 11.6 2.6 2.1 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 KIY50518.1 - 0.62 10.1 5.0 1.9 8.6 1.0 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, FA_desaturase PF00487.24 KIY50521.1 - 5.1e-25 88.8 23.4 7.2e-25 88.3 23.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIY50521.1 - 9.3e-09 35.3 0.0 1.7e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pal1 PF08316.11 KIY50522.1 - 2.1e-16 60.9 0.1 5.7e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein His_biosynth PF00977.21 KIY50523.1 - 1.2e-44 152.5 0.2 3.2e-44 151.1 0.2 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KIY50523.1 - 1.5e-17 64.0 0.0 2.4e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KIY50523.1 - 4.6e-08 32.9 0.0 8.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KIY50523.1 - 0.00033 20.6 0.0 0.0082 16.0 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 KIY50523.1 - 0.17 11.6 0.2 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 2-Hacid_dh_C PF02826.19 KIY50524.1 - 1.5e-50 171.1 0.0 2.6e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY50524.1 - 1.1e-33 115.7 0.0 1.5e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY50524.1 - 0.0044 17.2 0.1 0.021 15.0 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_M15_4 PF13539.6 KIY50524.1 - 0.035 14.6 0.0 0.96 10.0 0.0 2.4 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase AdoHcyase_NAD PF00670.21 KIY50524.1 - 0.039 14.0 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2597 PF10772.9 KIY50524.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) EcKinase PF02958.20 KIY50524.1 - 0.07 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF5528 PF17666.1 KIY50524.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5528) DUF5615 PF18480.1 KIY50524.1 - 0.15 11.9 0.0 0.47 10.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Ribosomal_L4 PF00573.22 KIY50525.1 - 1.2e-58 198.0 0.0 1.3e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.19 KIY50526.1 - 1.9e-32 112.3 0.8 2.2e-32 112.1 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRCT_2 PF16589.5 KIY50527.1 - 2.8e-20 72.5 0.0 1.3e-14 54.4 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY50527.1 - 0.0039 17.5 0.1 0.026 14.9 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain TIP49 PF06068.13 KIY50528.1 - 4.3e-157 522.8 0.7 5.6e-157 522.4 0.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KIY50528.1 - 6e-21 74.4 0.2 3.4e-20 71.9 0.2 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KIY50528.1 - 1.8e-08 34.9 1.2 1.2e-05 25.7 0.1 2.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIY50528.1 - 3.8e-06 26.7 0.2 0.0074 16.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KIY50528.1 - 1.9e-05 24.1 0.4 3.9e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KIY50528.1 - 4.5e-05 23.9 0.3 0.00025 21.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KIY50528.1 - 0.00059 19.3 1.9 0.015 14.7 0.2 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIY50528.1 - 0.0028 17.7 0.9 2.3 8.2 0.1 3.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY50528.1 - 0.0035 17.6 0.1 0.32 11.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY50528.1 - 0.025 14.2 0.4 0.076 12.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIY50528.1 - 0.043 12.9 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 KIY50528.1 - 0.047 14.0 3.4 0.46 10.8 2.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIY50528.1 - 0.066 13.4 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIY50528.1 - 0.1 12.1 0.2 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Ribosomal_L2_C PF03947.18 KIY50529.1 - 2.9e-54 182.6 0.6 6.1e-54 181.6 0.6 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KIY50529.1 - 2.1e-24 85.3 1.1 4.6e-24 84.2 1.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Methyltransf_16 PF10294.9 KIY50531.1 - 3.6e-17 62.6 0.0 5.9e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KIY50531.1 - 3.7e-07 30.8 0.0 7.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY50531.1 - 1.2e-06 28.4 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY50531.1 - 4.2e-06 27.4 0.0 8.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY50531.1 - 4.4e-05 23.1 0.0 8.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 KIY50531.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.13 KIY50531.1 - 0.001 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KIY50531.1 - 0.0025 17.7 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KIY50531.1 - 0.004 16.9 0.0 0.0063 16.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 KIY50531.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KIY50531.1 - 0.038 14.6 0.0 0.082 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KIY50531.1 - 0.044 13.3 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Thioredoxin PF00085.20 KIY50532.1 - 9.1e-26 89.9 0.1 1.1e-25 89.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIY50532.1 - 1e-07 32.4 0.1 3.1e-07 30.8 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIY50532.1 - 2.5e-07 30.9 0.0 4.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KIY50532.1 - 3e-07 30.4 0.0 3.4e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY50532.1 - 1.6e-06 27.9 0.1 1.7e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KIY50532.1 - 1.4e-05 24.9 0.1 1.6e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KIY50532.1 - 0.00043 19.7 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KIY50532.1 - 0.0005 20.2 0.0 0.00071 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KIY50532.1 - 0.0028 17.8 0.1 0.0072 16.5 0.1 1.6 1 1 0 1 1 1 1 Glutaredoxin DUF2847 PF11009.8 KIY50532.1 - 0.065 13.1 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Nop10p PF04135.12 KIY50533.1 - 3.2e-22 78.3 0.2 3.7e-22 78.1 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CRAL_TRIO PF00650.20 KIY50534.1 - 1.4e-36 125.6 0.0 2e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY50534.1 - 1.4e-05 25.2 0.1 2.5e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TPMT PF05724.11 KIY50534.1 - 0.046 13.4 0.3 0.083 12.5 0.0 1.5 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Glyco_hydro_53 PF07745.13 KIY50534.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Rax2 PF12768.7 KIY50535.1 - 0.048 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Meth_synt_2 PF01717.18 KIY50536.1 - 4.6e-19 68.9 0.0 2.4e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIY50536.1 - 2.9e-06 27.0 0.0 0.00089 18.9 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Ribosomal_L13e PF01294.18 KIY50537.1 - 2.7e-74 248.9 6.2 3.8e-74 248.4 6.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e WD40 PF00400.32 KIY50538.1 - 6.5e-42 140.7 13.9 1.2e-07 32.2 0.5 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KIY50538.1 - 8.5e-31 106.9 0.0 2.4e-30 105.4 0.0 1.7 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KIY50538.1 - 4.9e-09 36.4 0.1 0.0065 16.7 0.0 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY50538.1 - 0.017 15.0 0.0 2.3 8.0 0.0 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIY50538.1 - 0.21 10.2 5.6 19 3.8 0.1 3.5 3 1 0 4 4 4 0 Nucleoporin Nup120/160 RecQ_Zn_bind PF16124.5 KIY50540.1 - 5.8e-08 33.3 1.1 6.9e-08 33.1 0.2 1.6 2 0 0 2 2 2 1 RecQ zinc-binding TNFR_c6 PF00020.18 KIY50540.1 - 0.025 15.0 0.8 0.047 14.1 0.1 1.8 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region CfAFP PF05264.11 KIY50541.1 - 0.057 13.4 3.3 0.083 12.9 3.3 1.3 1 1 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) RecQ_Zn_bind PF16124.5 KIY50542.1 - 7.2e-08 33.1 1.2 1.3e-07 32.3 0.2 1.9 2 0 0 2 2 2 1 RecQ zinc-binding TNFR_c6 PF00020.18 KIY50542.1 - 0.027 14.8 2.0 0.053 13.9 0.1 2.4 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region Pkinase PF00069.25 KIY50543.1 - 6e-64 215.9 0.0 6.9e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50543.1 - 3.6e-43 147.7 0.0 4.6e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY50543.1 - 3.1e-11 43.1 0.0 1.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KIY50543.1 - 0.011 14.6 0.0 0.023 13.5 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KIY50543.1 - 0.013 15.5 0.0 0.077 12.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIY50543.1 - 0.036 13.7 0.0 0.097 12.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 KIY50543.1 - 0.042 12.8 0.0 0.079 11.9 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KIY50543.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HORMA PF02301.18 KIY50544.1 - 9.3e-18 64.6 0.3 2.1e-17 63.5 0.3 1.5 1 1 0 1 1 1 1 HORMA domain CPL PF08144.11 KIY50544.1 - 0.08 13.3 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 CPL (NUC119) domain Bmt2 PF11968.8 KIY50545.1 - 2.4e-60 204.1 0.0 3e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KIY50545.1 - 0.012 15.5 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Nucleoporin_N PF08801.11 KIY50546.1 - 7.1e-64 216.2 0.0 1.2e-63 215.4 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KIY50546.1 - 5.6e-28 98.1 0.7 2.5e-27 95.9 0.7 1.8 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal RINGv PF12906.7 KIY50547.1 - 6.5e-14 51.8 3.4 9.8e-14 51.2 3.4 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KIY50547.1 - 0.033 14.5 3.3 0.058 13.7 3.3 1.4 1 0 0 1 1 1 0 Ring finger domain zf-CSL PF05207.13 KIY50547.1 - 0.18 11.6 3.2 9.1 6.1 0.4 2.4 1 1 1 2 2 2 0 CSL zinc finger Mito_carr PF00153.27 KIY50548.1 - 1.6e-45 153.0 1.0 6e-16 58.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cut8 PF08559.10 KIY50550.1 - 2.8e-12 46.8 0.6 1e-11 44.9 0.4 1.9 3 0 0 3 3 3 1 Cut8, nuclear proteasome tether protein ThiJ_like PF17124.5 KIY50550.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like Cas1_AcylT PF07779.12 KIY50551.1 - 9.5e-142 473.2 20.2 1.5e-141 472.6 20.2 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KIY50551.1 - 0.00031 20.6 0.0 0.00079 19.3 0.0 1.6 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MnhB PF04039.13 KIY50551.1 - 7.2 6.9 14.5 0.16 12.3 2.5 3.8 1 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter Rhomboid PF01694.22 KIY50552.1 - 4e-33 114.5 17.2 1.8e-32 112.4 14.7 2.3 2 1 0 2 2 2 1 Rhomboid family Cuticle_1 PF08140.11 KIY50552.1 - 0.1 12.6 0.4 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Crustacean cuticle protein repeat Pkinase PF00069.25 KIY50553.1 - 1e-55 188.9 0.0 1.2e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50553.1 - 3.4e-42 144.5 0.0 4.2e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY50553.1 - 5.1e-07 29.3 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY50553.1 - 0.00012 21.0 0.0 0.00016 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY50553.1 - 0.0013 18.2 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY50553.1 - 0.048 13.3 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIY50553.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY50553.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF866 PF05907.13 KIY50554.1 - 4.6e-45 153.3 0.9 2.1e-29 102.4 0.1 2.0 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF866) DUF4379 PF14311.6 KIY50554.1 - 0.2 12.1 4.2 1.9 8.9 0.3 3.0 4 0 0 4 4 4 0 Probable Zinc-ribbon domain DIL PF01843.19 KIY50555.1 - 4.6e-27 94.3 1.1 8.8e-27 93.4 0.2 2.0 2 0 0 2 2 2 1 DIL domain Ank_4 PF13637.6 KIY50555.1 - 7.1e-07 29.7 0.0 0.00039 20.9 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY50555.1 - 1.3e-06 28.9 0.0 3.6e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY50555.1 - 0.00011 22.3 0.8 0.0081 16.6 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KIY50555.1 - 0.0014 18.9 0.0 0.0077 16.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KIY50555.1 - 0.0015 18.9 0.6 0.85 10.2 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeat MRP-S28 PF10213.9 KIY50556.1 - 6e-28 97.8 0.0 7.2e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF2019 PF09450.10 KIY50556.1 - 0.07 13.1 0.1 3.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) Rrp15p PF07890.12 KIY50557.1 - 3.1e-25 89.0 10.3 1.4e-24 86.9 10.3 1.9 1 1 0 1 1 1 1 Rrp15p DUF3437 PF11919.8 KIY50557.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Chorismate_bind PF00425.18 KIY50557.1 - 0.06 12.9 0.5 0.08 12.5 0.5 1.2 1 0 0 1 1 1 0 chorismate binding enzyme Ndc1_Nup PF09531.10 KIY50557.1 - 0.52 9.0 3.7 0.58 8.8 3.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SIR4_SID PF16991.5 KIY50557.1 - 1.1 9.3 6.5 0.26 11.3 3.3 1.6 2 0 0 2 2 2 0 Sir4 SID domain RR_TM4-6 PF06459.12 KIY50557.1 - 1.4 8.7 9.2 1.9 8.2 9.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CN_hydrolase PF00795.22 KIY50558.1 - 7.8e-47 159.8 0.0 8.9e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Septin PF00735.18 KIY50560.1 - 9.8e-118 392.5 0.0 9.8e-118 392.5 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KIY50560.1 - 6.2e-08 32.7 0.5 2e-07 31.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KIY50560.1 - 0.00034 20.9 0.1 0.0042 17.4 0.0 2.7 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIY50560.1 - 0.00039 20.4 0.7 0.00039 20.4 0.7 3.1 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KIY50560.1 - 0.00075 19.1 4.5 0.0066 16.0 0.0 3.4 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KIY50560.1 - 0.0019 18.8 6.0 0.02 15.4 0.7 2.8 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KIY50560.1 - 0.0032 17.2 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY50560.1 - 0.0063 16.9 0.1 0.026 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 KIY50560.1 - 0.007 16.0 0.0 0.063 12.9 0.0 2.4 2 0 0 2 2 2 1 Ras family AIG1 PF04548.16 KIY50560.1 - 0.013 14.8 2.0 0.02 14.3 0.0 2.3 3 0 0 3 3 3 0 AIG1 family Dynamin_N PF00350.23 KIY50560.1 - 0.027 14.6 6.1 1 9.4 0.1 3.2 2 1 1 3 3 3 0 Dynamin family Roc PF08477.13 KIY50560.1 - 0.033 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KIY50560.1 - 0.14 12.7 11.0 18 5.7 11.0 2.3 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 KIY50560.1 - 0.16 11.5 2.5 0.3 10.6 2.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KIY50560.1 - 0.44 9.6 3.6 0.69 8.9 3.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KIY50560.1 - 0.88 9.6 8.7 1.7 8.7 8.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Strep_SA_rep PF06696.11 KIY50560.1 - 2.3 8.3 9.3 0.27 11.3 3.8 2.2 1 1 1 2 2 2 0 Streptococcal surface antigen repeat ATP_bind_1 PF03029.17 KIY50560.1 - 2.4 7.9 7.6 4.5 7.0 0.1 3.3 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Xpo1 PF08389.12 KIY50561.1 - 2.5e-21 76.3 0.3 1.1e-19 71.0 0.1 3.0 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KIY50561.1 - 2.3e-09 37.0 0.0 1.5e-08 34.4 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 KIY50561.1 - 0.02 15.4 0.0 0.21 12.1 0.0 2.9 3 1 1 4 4 4 0 HEAT-like repeat CoA_binding PF02629.19 KIY50562.1 - 1.2e-29 102.8 1.6 2e-29 102.1 0.2 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KIY50562.1 - 2.7e-24 85.8 0.3 4.8e-24 84.9 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KIY50562.1 - 1.7e-11 44.1 0.2 4.5e-11 42.7 0.1 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KIY50562.1 - 2.7e-05 24.6 0.1 9e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 KIY50562.1 - 0.065 14.1 0.0 0.17 12.8 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Phage_GPO PF05929.11 KIY50562.1 - 0.092 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ACBP PF00887.19 KIY50563.1 - 3.4e-16 59.2 0.0 5.9e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 KIY50563.1 - 3e-12 46.5 0.1 6.7e-12 45.4 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY50563.1 - 1.6e-11 44.7 0.0 2.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIY50563.1 - 2e-10 40.6 0.2 2.4e-08 34.0 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KIY50563.1 - 2.2e-10 40.9 0.1 6.3e-05 23.4 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY50563.1 - 6e-08 32.4 0.2 1.3e-05 25.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Tox-REase-5 PF15648.6 KIY50563.1 - 0.05 14.1 0.0 0.092 13.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 Ribosomal_S16 PF00886.19 KIY50564.1 - 7.9e-21 73.9 0.0 9.3e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Arm PF00514.23 KIY50565.1 - 1.1e-89 292.0 14.0 2.8e-13 49.4 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KIY50565.1 - 2.6e-23 82.3 3.2 6e-23 81.1 3.2 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KIY50565.1 - 7.9e-22 77.4 2.0 9e-09 35.7 0.1 5.3 4 1 1 5 5 5 4 HEAT-like repeat Arm_3 PF16186.5 KIY50565.1 - 1.3e-20 72.7 1.5 2.7e-20 71.7 1.5 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 KIY50565.1 - 6.3e-18 65.0 0.2 0.00021 21.6 0.0 5.4 1 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 KIY50565.1 - 1.5e-15 56.0 0.2 4.1e-05 23.5 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.20 KIY50565.1 - 2.2e-06 26.5 0.0 0.00021 20.0 0.0 2.7 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.6 KIY50565.1 - 0.00013 22.1 1.2 0.027 14.7 0.0 4.1 3 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 KIY50565.1 - 0.00018 21.6 0.1 5 7.3 0.0 4.6 3 3 1 4 4 4 1 V-ATPase subunit H Arm_2 PF04826.13 KIY50565.1 - 0.00061 19.3 0.0 4.7 6.6 0.0 3.9 2 1 1 4 4 4 1 Armadillo-like HEAT_PBS PF03130.16 KIY50565.1 - 0.0022 18.5 2.2 0.93 10.4 0.2 4.0 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 KIY50565.1 - 0.012 15.0 0.0 0.25 10.6 0.0 2.1 2 0 0 2 2 2 0 Mo25-like SEN1_N PF12726.7 KIY50565.1 - 0.029 12.6 0.2 14 3.7 0.0 3.5 4 1 0 4 4 4 0 SEN1 N terminal V-ATPase_H_N PF03224.14 KIY50565.1 - 0.1 11.9 0.0 8.1 5.6 0.0 2.9 1 1 1 3 3 3 0 V-ATPase subunit H Nipped-B_C PF12830.7 KIY50565.1 - 0.12 12.3 0.5 4.5 7.2 0.1 2.8 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus MMS19_N PF14500.6 KIY50565.1 - 0.2 11.2 0.0 7.2 6.1 0.0 2.6 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF3552 PF12072.8 KIY50565.1 - 2.7 7.4 7.0 4.4 6.7 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Abhydrolase_1 PF00561.20 KIY50566.1 - 1.9e-07 31.0 0.0 2.9e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY50566.1 - 2.6e-05 23.6 0.0 0.00016 21.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LSM PF01423.22 KIY50567.1 - 2.1e-21 75.4 0.1 2.3e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY50567.1 - 0.011 15.9 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain RPN2_C PF18004.1 KIY50568.1 - 2.2e-41 141.4 0.0 1.1e-39 136.0 0.0 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KIY50568.1 - 2.2e-23 81.4 35.6 3e-07 30.5 0.1 8.9 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KIY50568.1 - 3e-17 62.8 2.9 3e-14 53.2 0.2 4.7 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KIY50568.1 - 6.3e-05 22.9 0.7 1.2 9.6 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KIY50568.1 - 0.00016 22.1 3.0 0.62 10.6 0.3 5.1 2 1 2 4 4 4 2 HEAT-like repeat Arm PF00514.23 KIY50568.1 - 0.021 14.9 3.1 2.7 8.2 0.1 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KIY50568.1 - 0.067 11.7 0.0 0.32 9.5 0.0 1.9 2 0 0 2 2 2 0 Adaptin N terminal region COX6A PF02046.15 KIY50569.1 - 2e-26 92.7 0.3 2.4e-26 92.4 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa LAG1-DNAbind PF09271.11 KIY50570.1 - 7.3e-24 85.1 0.0 2e-21 77.2 0.0 2.3 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KIY50570.1 - 8.6e-23 81.3 0.0 1.9e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF3123 PF11321.8 KIY50570.1 - 0.84 10.3 3.4 0.94 10.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) PK PF00224.21 KIY50571.1 - 3.8e-163 542.3 0.2 5.1e-163 541.9 0.2 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KIY50571.1 - 3e-37 127.4 0.0 8e-37 126.1 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KIY50571.1 - 0.00015 21.0 0.6 0.00044 19.5 0.6 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KIY50571.1 - 0.0034 16.4 0.0 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Gly_transf_sug PF04488.15 KIY50572.1 - 3.8e-05 24.2 0.0 8.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIY50572.1 - 0.049 13.0 0.2 0.082 12.3 0.2 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Exo70 PF03081.15 KIY50573.1 - 0.015 14.3 3.1 0.3 10.1 3.1 2.1 1 1 0 1 1 1 0 Exo70 exocyst complex subunit DUF1521 PF07481.11 KIY50573.1 - 0.045 13.8 1.2 1.3 9.0 0.1 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1521) TM_helix PF05552.12 KIY50573.1 - 4.6 7.3 6.9 0.28 11.2 0.7 2.0 2 0 0 2 2 2 0 Conserved TM helix Ribul_P_3_epim PF00834.19 KIY50574.1 - 6e-55 185.7 0.0 7.4e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 KIY50574.1 - 0.087 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain PPR_2 PF13041.6 KIY50575.1 - 8e-42 141.2 2.2 9.8e-09 35.3 0.1 9.3 4 3 6 10 10 10 9 PPR repeat family PPR_3 PF13812.6 KIY50575.1 - 1.1e-29 102.3 0.0 1.5e-07 31.4 0.0 7.2 5 2 1 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.20 KIY50575.1 - 6.7e-20 69.9 9.6 0.025 14.8 0.0 10.8 12 0 0 12 12 12 4 PPR repeat PPR_1 PF12854.7 KIY50575.1 - 5.2e-16 58.0 7.5 0.17 11.6 0.0 9.5 10 0 0 10 10 10 5 PPR repeat PPR_long PF17177.4 KIY50575.1 - 6.9e-12 45.2 0.0 0.0025 17.2 0.0 3.8 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KIY50575.1 - 0.083 13.7 1.2 29 5.8 0.6 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Cas_Cas02710 PF09670.10 KIY50575.1 - 0.091 11.5 0.1 0.17 10.6 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) ATP13 PF12921.7 KIY50575.1 - 0.15 12.0 0.1 0.51 10.2 0.1 1.9 1 1 0 1 1 1 0 Mitochondrial ATPase expression Sugar_tr PF00083.24 KIY50577.1 - 3.6e-96 322.8 8.3 4.4e-96 322.5 8.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY50577.1 - 2.8e-22 79.1 40.7 2.4e-20 72.8 16.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 KIY50578.1 - 9e-18 64.7 0.0 1.7e-17 63.7 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY50578.1 - 0.00046 20.5 0.0 0.0016 18.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIY50578.1 - 0.0066 15.2 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KIY50578.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4203 PF13886.6 KIY50579.1 - 2.5e-52 177.5 28.0 2.5e-52 177.5 28.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Pro_isomerase PF00160.21 KIY50580.1 - 2.4e-46 157.9 0.0 3.7e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-Nse PF11789.8 KIY50580.1 - 0.001 18.8 0.2 0.0078 16.0 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KIY50580.1 - 0.007 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 U-box domain Snf7 PF03357.21 KIY50581.1 - 1.1e-23 83.8 1.8 1.3e-23 83.5 1.8 1.0 1 0 0 1 1 1 1 Snf7 PT-HINT PF07591.11 KIY50581.1 - 0.016 15.5 0.2 0.021 15.1 0.2 1.1 1 0 0 1 1 1 0 Pretoxin HINT domain DUF3916 PF13079.6 KIY50581.1 - 0.064 13.1 1.4 6.6 6.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3916) PP2C PF00481.21 KIY50582.1 - 6.6e-34 117.7 0.0 5e-33 114.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C G_glu_transpept PF01019.21 KIY50583.1 - 6.7e-142 473.8 0.0 7.7e-142 473.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Prefoldin_2 PF01920.20 KIY50584.1 - 1e-20 73.6 8.0 1.6e-20 73.0 8.0 1.3 1 1 0 1 1 1 1 Prefoldin subunit APG6_N PF17675.1 KIY50584.1 - 0.002 18.7 6.4 0.0095 16.5 0.7 2.0 1 1 1 2 2 2 1 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KIY50584.1 - 0.011 15.8 9.1 0.081 12.9 1.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_3 PF13758.6 KIY50584.1 - 0.011 15.8 2.6 0.012 15.7 2.0 1.4 1 1 0 1 1 1 0 Prefoldin subunit Tup_N PF08581.10 KIY50584.1 - 0.044 14.1 4.8 7.1 7.0 0.3 3.0 2 1 1 3 3 3 0 Tup N-terminal End3 PF12761.7 KIY50584.1 - 0.08 13.1 4.5 0.1 12.7 4.5 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 GAS PF13851.6 KIY50584.1 - 0.26 10.6 10.3 2.6 7.3 10.3 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4404 PF14357.6 KIY50584.1 - 0.33 11.6 5.5 0.99 10.1 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Prefoldin PF02996.17 KIY50584.1 - 0.37 10.7 8.7 0.047 13.6 2.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit YgaB PF14182.6 KIY50584.1 - 0.53 10.7 6.3 0.11 13.0 1.1 2.3 2 2 0 2 2 2 0 YgaB-like protein PHM7_cyt PF14703.6 KIY50584.1 - 0.61 10.3 4.6 0.92 9.7 4.6 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_S17 PF00366.20 KIY50585.1 - 2.1e-18 66.2 0.3 2.6e-18 65.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 ANAPC4_WD40 PF12894.7 KIY50586.1 - 8.1e-11 42.1 0.0 0.0091 16.3 0.0 5.4 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY50586.1 - 2.7e-06 28.0 4.7 0.044 14.7 0.1 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.11 KIY50586.1 - 0.0024 17.8 0.1 4.1 7.2 0.0 4.2 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KIY50586.1 - 0.019 13.0 0.0 0.41 8.6 0.0 2.5 3 0 0 3 3 3 0 IKI3 family Lactonase PF10282.9 KIY50586.1 - 0.091 12.0 0.0 7.3 5.7 0.0 2.5 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller MFS_1 PF07690.16 KIY50587.1 - 2.2e-36 125.5 22.9 2.8e-36 125.2 22.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY50587.1 - 1.4e-13 50.6 8.6 1.7e-13 50.3 8.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIY50587.1 - 2.9e-12 45.8 3.6 3.8e-12 45.4 3.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIY50587.1 - 9.1e-07 28.5 5.6 1.4e-06 27.9 5.6 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Peptidase_M41 PF01434.18 KIY50588.1 - 2.2e-65 220.1 0.0 3.6e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KIY50588.1 - 2.2e-42 144.6 0.0 4.6e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY50588.1 - 5.4e-16 58.1 0.2 1.5e-15 56.7 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KIY50588.1 - 0.0026 17.0 0.7 0.0052 16.0 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 KIY50588.1 - 0.0076 16.6 0.1 0.22 11.9 0.1 2.5 1 1 0 2 2 2 1 AAA ATPase domain FtsH_ext PF06480.15 KIY50588.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 FtsH Extracellular AAA_5 PF07728.14 KIY50588.1 - 0.026 14.5 0.1 0.12 12.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIY50588.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KIY50588.1 - 0.045 13.9 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KIY50588.1 - 0.052 13.3 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KIY50588.1 - 0.064 13.5 0.1 1.4 9.2 0.1 2.5 1 1 0 2 2 2 0 AAA domain Cgr1 PF03879.14 KIY50589.1 - 7.2e-30 103.5 21.3 8e-30 103.4 21.3 1.0 1 0 0 1 1 1 1 Cgr1 family CENP-B_dimeris PF09026.10 KIY50590.1 - 0.84 10.1 10.8 1.9 8.9 10.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PAT1 PF09770.9 KIY50590.1 - 1.6 6.9 5.2 0.26 9.5 1.0 1.6 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PBP1_TM PF14812.6 KIY50590.1 - 3.7 8.0 10.0 11 6.5 10.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec39 PF08314.11 KIY50591.1 - 5.6e-97 326.0 0.0 7.4e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 FANC_SAP PF18081.1 KIY50591.1 - 0.058 13.6 0.2 0.83 9.9 0.0 2.8 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Fungal_trans PF04082.18 KIY50592.1 - 8.1e-09 34.9 0.1 1.9e-08 33.7 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY50592.1 - 0.0001 22.4 9.9 0.00017 21.6 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KIY50593.1 - 1.9e-06 27.6 4.5 1.9e-05 24.4 0.3 3.1 1 1 1 2 2 2 2 F-box-like LSM PF01423.22 KIY50594.1 - 8.7e-19 67.0 0.1 1.3e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIY50594.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Hfq protein HABP4_PAI-RBP1 PF04774.15 KIY50595.1 - 1.1e-12 48.8 7.1 1.1e-12 48.8 7.1 2.3 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family ABC_tran PF00005.27 KIY50596.1 - 1e-50 171.8 0.0 3.1e-31 108.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY50596.1 - 2.2e-47 162.0 20.7 2.2e-27 96.4 3.7 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KIY50596.1 - 6e-08 32.4 0.0 0.00037 20.0 0.2 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KIY50596.1 - 5.7e-06 25.6 0.3 0.012 14.7 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 KIY50596.1 - 9.4e-06 25.3 0.1 0.04 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KIY50596.1 - 2e-05 24.6 4.7 0.66 9.7 0.1 4.5 4 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY50596.1 - 0.00017 21.3 0.3 0.38 10.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY50596.1 - 0.00059 20.3 0.7 1.4 9.2 0.4 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KIY50596.1 - 0.0018 18.8 0.4 0.4 11.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 KIY50596.1 - 0.0049 16.9 0.0 0.31 11.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 KIY50596.1 - 0.0065 16.8 1.2 20 5.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KIY50596.1 - 0.015 15.4 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 KIY50596.1 - 0.027 14.4 0.0 8.9 6.2 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KIY50596.1 - 0.027 14.6 0.2 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KIY50596.1 - 0.045 13.7 0.9 2.6 8.0 0.1 3.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KIY50596.1 - 0.18 12.0 0.2 15 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain E1_DerP2_DerF2 PF02221.15 KIY50597.1 - 7.4e-23 81.5 0.2 8.9e-23 81.2 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KIY50597.1 - 0.005 17.2 0.0 0.0096 16.3 0.0 1.5 1 1 0 1 1 1 1 ML-like domain PSI_PsaJ PF01701.18 KIY50598.1 - 0.085 13.4 3.1 0.22 12.1 3.1 1.7 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ SHP PF03579.13 KIY50598.1 - 0.13 12.2 2.5 0.37 10.8 1.3 2.0 1 1 1 2 2 2 0 Small hydrophobic protein DUF3043 PF11241.8 KIY50598.1 - 0.51 10.4 1.2 0.64 10.0 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) DUF5362 PF17319.2 KIY50598.1 - 3.1 7.7 7.9 14 5.6 7.6 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5362) Memo PF01875.17 KIY50602.1 - 9.2e-72 241.4 0.0 1.1e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein His_Phos_1 PF00300.22 KIY50603.1 - 1.7e-20 73.6 0.0 2.4e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SLR1-BP PF07333.12 KIY50604.1 - 0.92 10.0 4.1 18 5.9 0.5 2.4 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Vps36-NZF-N PF16988.5 KIY50605.1 - 0.014 14.8 0.7 0.38 10.2 0.1 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Med5 PF08689.10 KIY50606.1 - 2.7e-10 38.8 1.4 1.3e-09 36.6 0.1 2.4 2 1 0 2 2 2 1 Mediator complex subunit Med5 Cation_efflux PF01545.21 KIY50607.1 - 1e-46 159.2 12.4 3.8e-46 157.3 12.4 1.8 1 1 0 1 1 1 1 Cation efflux family JAB PF01398.21 KIY50608.1 - 1e-14 54.5 0.0 2.1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KIY50608.1 - 0.011 15.8 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) HAUS6_N PF14661.6 KIY50608.1 - 0.081 12.5 0.0 11 5.6 0.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Coprogen_oxidas PF01218.18 KIY50611.1 - 9.4e-108 359.4 0.0 1.2e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Helo_like_N PF17111.5 KIY50612.1 - 0.095 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Tim17 PF02466.19 KIY50613.1 - 2.2e-07 31.2 6.2 6.9e-07 29.6 6.2 1.8 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Oxidored_q6 PF01058.22 KIY50613.1 - 0.033 14.0 0.0 0.087 12.6 0.0 1.7 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF5518 PF17647.1 KIY50613.1 - 0.066 13.4 9.8 1.7 8.8 1.2 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5518) TraT PF05818.12 KIY50613.1 - 8.2 6.0 7.5 7.9 6.1 0.6 2.0 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Ctr PF04145.15 KIY50614.1 - 0.0015 19.2 8.2 0.013 16.2 2.9 2.3 1 1 1 2 2 2 2 Ctr copper transporter family BUD22 PF09073.10 KIY50617.1 - 0.53 9.6 10.9 0.51 9.6 10.9 1.1 1 0 0 1 1 1 0 BUD22 ABC2_membrane PF01061.24 KIY50620.1 - 4e-83 278.0 47.5 1.9e-45 154.9 18.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KIY50620.1 - 1.9e-36 123.9 4.2 2.5e-34 117.0 0.1 4.2 4 0 0 4 4 4 2 CDR ABC transporter ABC_tran PF00005.27 KIY50620.1 - 1.3e-33 116.4 0.0 1.4e-17 64.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KIY50620.1 - 9e-13 48.7 0.0 2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIY50620.1 - 1.8e-05 25.2 0.1 0.014 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KIY50620.1 - 2.3e-05 24.1 0.2 0.00026 20.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIY50620.1 - 0.00063 19.7 0.1 0.037 13.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KIY50620.1 - 0.00087 19.5 0.1 0.31 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KIY50620.1 - 0.0013 17.9 37.3 0.038 13.1 13.3 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 KIY50620.1 - 0.014 15.9 0.0 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIY50620.1 - 0.024 14.6 0.6 2.1 8.2 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KIY50620.1 - 0.032 13.9 0.1 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIY50620.1 - 0.043 13.6 0.7 1.6 8.5 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY50620.1 - 0.067 13.5 0.1 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIY50620.1 - 0.82 9.2 1.9 1 8.9 0.2 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cnd1 PF12717.7 KIY50621.1 - 0.031 14.3 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Gcn1_N PF12074.8 KIY50621.1 - 0.049 12.9 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Arm PF00514.23 KIY50621.1 - 0.13 12.4 4.1 0.96 9.6 0.0 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RRN3 PF05327.11 KIY50621.1 - 1.7 7.1 3.1 30 3.0 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Eaf7 PF07904.13 KIY50622.1 - 0.026 14.9 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 Sin3a_C PF16879.5 KIY50623.1 - 1.6e-74 251.2 0.1 4e-74 249.9 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KIY50623.1 - 3.3e-35 120.1 0.0 7.6e-35 118.9 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KIY50623.1 - 1.8e-30 104.8 6.5 7e-10 38.9 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Zn-C2H2_12 PF18112.1 KIY50623.1 - 0.018 15.5 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain OPT PF03169.15 KIY50624.1 - 1.2e-114 384.3 49.3 1.3e-114 384.1 49.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MOSP_N PF02707.16 KIY50624.1 - 0.028 14.2 0.0 0.89 9.3 0.0 2.3 2 0 0 2 2 2 0 Major Outer Sheath Protein N-terminal region Ank_5 PF13857.6 KIY50625.1 - 1.1e-12 47.9 2.2 1.4e-10 41.2 0.3 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY50625.1 - 8.9e-11 42.2 0.0 1.4e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY50625.1 - 1.2e-10 41.7 0.8 1.3e-05 25.7 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY50625.1 - 6.2e-09 35.4 0.3 5e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIY50625.1 - 9.6e-09 35.3 0.3 2.2e-06 27.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat WLM PF08325.10 KIY50626.1 - 4.8e-45 154.0 0.1 8.6e-45 153.2 0.0 1.4 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 KIY50626.1 - 3e-11 42.4 25.9 7.2e-08 31.6 2.0 4.0 3 1 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KIY50626.1 - 0.00054 19.9 16.1 0.022 14.8 10.3 2.4 1 1 1 2 2 2 2 Double zinc ribbon DUF45 PF01863.17 KIY50626.1 - 0.018 15.1 0.2 0.037 14.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 FYVE_2 PF02318.16 KIY50626.1 - 1.5 9.0 8.3 0.43 10.8 3.5 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger SNF2_N PF00176.23 KIY50627.1 - 1.4e-69 234.5 0.0 1.8e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY50627.1 - 7.9e-15 55.2 0.0 2.2e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 KIY50627.1 - 4.9e-09 36.0 0.0 1.6e-08 34.3 0.0 1.9 2 0 0 2 2 1 1 HIRAN domain ResIII PF04851.15 KIY50627.1 - 8.7e-07 29.1 0.0 2.4e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KIY50627.1 - 1.1e-06 28.3 13.1 1.5e-05 24.7 12.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KIY50627.1 - 1.2e-05 25.2 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 KIY50627.1 - 1.4e-05 25.0 9.1 2.5e-05 24.2 7.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY50627.1 - 2.3e-05 24.2 11.1 4.2e-05 23.3 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY50627.1 - 6.4e-05 23.2 10.2 0.00013 22.2 10.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY50627.1 - 0.00013 21.7 8.9 0.00022 21.0 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY50627.1 - 0.00025 21.1 10.7 0.0005 20.2 10.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KIY50627.1 - 0.013 15.3 5.3 0.032 14.0 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KIY50627.1 - 0.02 14.6 7.6 0.038 13.7 7.6 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.6 KIY50627.1 - 0.028 14.4 9.7 0.05 13.6 9.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 KIY50627.1 - 0.063 13.6 6.0 0.17 12.2 5.3 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIY50627.1 - 0.39 10.8 3.1 1.2 9.3 3.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KIY50627.1 - 0.49 10.3 3.6 1.2 9.1 3.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Di19 PF05605.12 KIY50627.1 - 4.9 7.5 6.8 1.3 9.4 0.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 KIY50627.1 - 9.2 6.2 9.6 45 4.0 9.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Cpn60_TCP1 PF00118.24 KIY50628.1 - 9.6e-156 519.2 0.5 1.1e-155 519.0 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3552 PF12072.8 KIY50629.1 - 0.013 14.9 9.3 0.013 14.9 9.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) TauD PF02668.16 KIY50630.1 - 3.5e-53 181.1 1.3 4.5e-53 180.8 1.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KIY50631.1 - 4.6e-23 81.7 16.8 4.6e-23 81.7 16.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD-oxidase_C PF02913.19 KIY50632.1 - 8.1e-51 173.1 0.0 1e-50 172.7 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIY50632.1 - 2.7e-34 117.9 0.1 4.5e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ESAG1 PF03238.13 KIY50632.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 ESAG protein MFS_1 PF07690.16 KIY50633.1 - 1e-20 74.0 16.4 1e-20 74.0 16.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.16 KIY50634.1 - 9.4e-58 196.1 1.7 1.2e-57 195.8 1.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Collagen PF01391.18 KIY50635.1 - 0.0022 17.7 3.8 0.0048 16.6 3.8 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF3552 PF12072.8 KIY50635.1 - 0.043 13.2 28.0 0.026 13.9 9.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Zn_clus PF00172.18 KIY50637.1 - 8.9e-08 32.1 5.5 1.2e-07 31.7 5.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1501 PF07394.12 KIY50637.1 - 0.18 10.8 0.1 0.21 10.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cytochrom_C PF00034.21 KIY50637.1 - 0.64 11.2 5.0 2.3 9.4 5.0 1.7 1 1 0 1 1 1 0 Cytochrome c HLH PF00010.26 KIY50638.1 - 9.2e-07 28.7 0.0 2e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain SRP-alpha_N PF04086.13 KIY50638.1 - 0.088 12.7 4.0 0.11 12.4 4.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SPX PF03105.19 KIY50638.1 - 0.34 10.8 10.8 0.41 10.5 10.8 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 KIY50638.1 - 2.2 6.9 8.6 2.5 6.7 8.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAD-oxidase_C PF02913.19 KIY50640.1 - 1.1e-48 166.1 0.0 1.3e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIY50640.1 - 2.3e-34 118.1 0.2 4.4e-34 117.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HTH_Tnp_Tc5 PF03221.16 KIY50641.1 - 7.7e-09 35.5 0.1 9.1e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF613 PF04764.12 KIY50642.1 - 0.017 15.3 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF613) MAT1 PF06391.13 KIY50643.1 - 0.0024 17.7 5.0 0.0024 17.7 5.0 2.4 2 1 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 DivIC PF04977.15 KIY50643.1 - 0.031 14.1 1.0 0.031 14.1 1.0 2.0 2 0 0 2 2 2 0 Septum formation initiator NIF PF03031.18 KIY50645.1 - 4.2e-23 81.8 0.0 3.2e-22 79.0 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KIY50645.1 - 4e-08 33.1 0.2 1.9e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KIY50645.1 - 0.00014 22.2 0.0 0.00042 20.6 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIY50645.1 - 0.0063 16.8 0.1 0.17 12.2 0.0 2.9 2 1 1 3 3 3 1 DNA ligase 3 BRCT domain Med21 PF11221.8 KIY50645.1 - 0.099 12.9 4.8 0.19 12.0 4.8 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex zf-MYND PF01753.18 KIY50646.1 - 4.9e-10 39.3 15.2 4.9e-10 39.3 15.2 1.8 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIY50646.1 - 0.57 10.5 14.7 1.2 9.5 14.7 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Tannase PF07519.11 KIY50647.1 - 1.4e-86 291.3 0.0 1.8e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KIY50647.1 - 0.13 11.5 0.0 14 4.9 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BSP PF04450.12 KIY50648.1 - 7.7e-57 192.4 0.0 8.6e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 KIY50648.1 - 0.0023 17.8 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Aspzincin_M35 PF14521.6 KIY50648.1 - 0.0082 16.7 0.0 0.012 16.2 0.0 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase WLM PF08325.10 KIY50648.1 - 0.015 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 WLM domain Peptidase_M48 PF01435.18 KIY50648.1 - 0.098 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 WD40 PF00400.32 KIY50649.1 - 5.3e-15 55.6 20.7 0.0051 17.6 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40 PF00400.32 KIY50650.1 - 4.7e-37 125.3 7.5 4.6e-07 30.4 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY50650.1 - 3.6e-15 56.0 0.1 0.0016 18.7 0.0 5.1 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY50650.1 - 2.7e-07 30.6 0.0 7.8e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIY50650.1 - 0.00033 20.1 0.0 0.27 10.5 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain LisH PF08513.11 KIY50650.1 - 0.0009 19.1 0.4 0.0019 18.1 0.0 1.8 2 0 0 2 2 1 1 LisH Ge1_WD40 PF16529.5 KIY50650.1 - 0.0016 17.5 0.1 0.58 9.1 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIY50650.1 - 0.0025 17.7 0.4 0.23 11.4 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIY50650.1 - 0.005 15.5 0.4 5 5.7 0.0 3.1 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIY50650.1 - 0.0062 15.1 0.0 2.1 6.8 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_3 PF15911.5 KIY50650.1 - 0.031 14.3 0.2 3.4 7.8 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat TALPID3 PF15324.6 KIY50650.1 - 2 6.0 15.6 2.6 5.6 15.6 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Cerato-platanin PF07249.12 KIY50651.1 - 1.3e-48 164.0 1.6 1.6e-48 163.8 1.6 1.0 1 0 0 1 1 1 1 Cerato-platanin DUF4148 PF13663.6 KIY50651.1 - 0.04 14.1 0.4 0.062 13.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Arginase PF00491.21 KIY50652.1 - 3.2e-89 299.1 0.1 4.2e-89 298.8 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KIY50652.1 - 0.078 13.2 0.2 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 UPF0489 domain SUR7 PF06687.12 KIY50653.1 - 2.7e-18 66.4 18.9 4.2e-18 65.8 18.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF996 PF06195.13 KIY50653.1 - 0.16 12.2 13.4 0.63 10.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Cerato-platanin PF07249.12 KIY50654.1 - 1.5e-49 167.1 4.6 1.7e-49 166.9 4.6 1.0 1 0 0 1 1 1 1 Cerato-platanin UCR_UQCRX_QCR9 PF05365.12 KIY50654.1 - 1.3 9.1 3.3 0.87 9.6 0.9 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Cerato-platanin PF07249.12 KIY50655.1 - 4.5e-43 146.1 1.6 5.3e-43 145.9 1.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Mem_trans PF03547.18 KIY50656.1 - 4.2e-24 84.7 2.2 9.5e-24 83.5 2.2 1.5 1 1 0 1 1 1 1 Membrane transport protein TauD PF02668.16 KIY50657.1 - 1.5e-51 175.7 1.9 2e-51 175.3 1.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cerato-platanin PF07249.12 KIY50658.1 - 8.7e-48 161.3 2.0 1e-47 161.1 2.0 1.0 1 0 0 1 1 1 1 Cerato-platanin eIF_4G1 PF12152.8 KIY50659.1 - 0.0077 16.4 0.0 3.9 7.7 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 4G1 Collagen PF01391.18 KIY50659.1 - 0.011 15.5 2.1 0.011 15.5 2.1 1.5 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Serglycin PF04360.12 KIY50659.1 - 0.044 13.7 0.3 8.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Serglycin Phage_tail_APC PF16778.5 KIY50659.1 - 0.14 12.1 0.4 21 5.1 0.1 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Cerato-platanin PF07249.12 KIY50660.1 - 5.5e-45 152.3 0.7 6.5e-45 152.1 0.7 1.1 1 0 0 1 1 1 1 Cerato-platanin GTP_EFTU PF00009.27 KIY50661.1 - 1.1e-66 224.2 0.1 1.7e-66 223.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIY50661.1 - 1.5e-34 118.3 0.0 9.4e-34 115.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KIY50661.1 - 3.3e-23 81.5 0.0 7.3e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIY50661.1 - 9.6e-14 51.5 0.0 2.7e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KIY50661.1 - 2.6e-13 49.9 0.0 6.7e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KIY50661.1 - 0.0014 18.7 0.2 0.0033 17.5 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KIY50661.1 - 0.16 11.7 0.4 0.54 10.0 0.2 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Abhydrolase_6 PF12697.7 KIY50662.1 - 1.5e-06 29.0 0.0 1.7e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY50662.1 - 0.0042 16.8 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY50662.1 - 0.006 15.9 0.0 0.0086 15.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KIY50662.1 - 0.062 12.3 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Importin_rep PF18773.1 KIY50663.1 - 2.2e-10 40.1 0.4 4.3e-10 39.1 0.4 1.5 1 0 0 1 1 1 1 Importin 13 repeat Xpo1 PF08389.12 KIY50663.1 - 0.00078 19.5 0.1 0.0078 16.3 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein Importin_rep_3 PF18806.1 KIY50663.1 - 0.016 15.3 0.1 0.044 13.8 0.1 1.9 1 0 0 1 1 1 0 Importin 13 repeat CRM1_C PF08767.11 KIY50663.1 - 0.09 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 CRM1 C terminal RhoGAP PF00620.27 KIY50664.1 - 2.1e-29 102.3 0.0 3.8e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KIY50664.1 - 6.6e-22 78.2 0.0 6e-21 75.0 0.0 2.2 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Het-C PF07217.11 KIY50666.1 - 5.1e-197 655.8 0.0 6.7e-197 655.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C 4HBT PF03061.22 KIY50667.1 - 1.2e-08 35.1 0.1 2.2e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily APH PF01636.23 KIY50668.1 - 3.6e-05 23.8 0.0 3.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY50668.1 - 0.00032 20.4 0.0 0.00032 20.3 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KIY50668.1 - 0.012 14.5 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KIY50668.1 - 0.07 12.4 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.16 KIY50669.1 - 1.7e-40 139.1 29.9 1.7e-40 139.1 29.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY50669.1 - 0.0013 17.6 1.1 0.0013 17.6 1.1 2.6 2 1 1 3 3 3 1 MFS_1 like family Zn_clus PF00172.18 KIY50671.1 - 3.2 8.0 14.5 8.4 6.6 2.4 2.2 1 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 KIY50672.1 - 5.8e-08 32.5 0.0 1.9e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sas10_Utp3 PF04000.15 KIY50673.1 - 1.2e-12 48.2 0.0 2.3e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RSN1_7TM PF02714.15 KIY50674.1 - 5.1e-13 49.0 19.6 7.5e-13 48.4 19.6 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KIY50674.1 - 0.018 15.2 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter Pkinase PF00069.25 KIY50675.1 - 5.2e-42 144.0 0.0 6.4e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50675.1 - 3.6e-33 115.0 0.0 4.1e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY50675.1 - 7e-05 21.9 0.0 9e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY50675.1 - 0.00023 21.2 0.0 0.11 12.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY50675.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Ribonuc_L-PSP PF01042.21 KIY50676.1 - 2.2e-34 118.0 0.0 2.5e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YcbB PF08664.10 KIY50676.1 - 0.17 11.9 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 YcbB domain Calpain_III PF01067.22 KIY50677.1 - 1.1e-14 54.9 0.2 4.9e-06 26.9 0.1 3.8 2 2 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.18 KIY50677.1 - 5e-08 32.9 1.7 8.4e-08 32.2 1.7 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Peptidase_C2 PF00648.21 KIY50677.1 - 4.8e-07 29.1 0.0 2.5e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease RicinB_lectin_2 PF14200.6 KIY50678.1 - 7.5e-05 23.4 0.0 0.0048 17.6 0.0 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Bot1p PF12298.8 KIY50679.1 - 3.7e-26 92.3 0.4 4.9e-26 91.9 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Methyltransf_16 PF10294.9 KIY50680.1 - 2.5e-17 63.2 0.0 3.8e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KIY50680.1 - 0.023 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CAP59_mtransfer PF11735.8 KIY50681.1 - 4.8e-37 127.9 0.0 9.5e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Orthoreo_P17 PF07272.11 KIY50681.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus P17 protein MFS_1 PF07690.16 KIY50682.1 - 5.9e-13 48.5 35.7 2e-12 46.7 21.8 2.7 2 2 0 2 2 2 2 Major Facilitator Superfamily SF3b10 PF07189.11 KIY50684.1 - 5.8e-35 119.2 0.0 7e-35 119.0 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) TFIID_30kDa PF03540.13 KIY50685.1 - 4.5e-26 90.5 0.1 6.4e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KIY50685.1 - 0.0027 17.7 0.0 0.089 12.8 0.0 2.2 2 0 0 2 2 2 1 Bromodomain associated Ribosomal_60s PF00428.19 KIY50685.1 - 0.11 13.1 0.0 0.74 10.4 0.0 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein LRR_4 PF12799.7 KIY50686.1 - 2.9e-05 24.3 1.8 0.75 10.3 0.1 5.4 4 2 3 7 7 7 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY50686.1 - 9.4e-05 22.2 0.0 0.00032 20.5 0.0 2.0 1 1 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KIY50686.1 - 0.0066 16.8 2.4 5.2 8.0 0.1 4.8 4 0 0 4 4 4 1 Leucine Rich Repeat F-box PF00646.33 KIY50686.1 - 0.012 15.4 0.2 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 F-box domain DUF1699 PF08004.11 KIY50686.1 - 0.2 11.4 0.0 0.87 9.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) HLH PF00010.26 KIY50687.1 - 2.2e-11 43.5 1.4 2.2e-11 43.5 1.4 2.5 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain DUF1192 PF06698.11 KIY50687.1 - 0.00043 20.3 0.5 0.00043 20.3 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Spc29 PF17082.5 KIY50687.1 - 0.0068 16.3 3.5 0.009 15.9 3.5 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 TolA_bind_tri PF16331.5 KIY50687.1 - 0.011 15.8 3.0 0.011 15.8 3.0 2.3 1 1 0 2 2 2 0 TolA binding protein trimerisation DASH_Dam1 PF08653.10 KIY50687.1 - 0.024 14.4 0.2 0.044 13.6 0.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 MAD PF05557.13 KIY50687.1 - 0.044 12.1 5.8 0.053 11.9 5.8 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Wtap PF17098.5 KIY50687.1 - 0.092 12.7 5.6 0.19 11.7 4.6 1.7 1 1 1 2 2 2 0 WTAP/Mum2p family DivIC PF04977.15 KIY50687.1 - 0.099 12.4 8.5 0.17 11.7 1.6 2.2 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KIY50687.1 - 0.11 13.0 5.5 0.17 12.4 5.5 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 KIY50687.1 - 0.13 11.0 2.6 0.15 10.9 2.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mt_ATP-synt_B PF05405.14 KIY50687.1 - 0.15 11.7 1.6 0.19 11.3 1.6 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CENP-F_leu_zip PF10473.9 KIY50687.1 - 0.15 12.1 6.4 0.18 11.9 6.4 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 KIY50687.1 - 0.21 11.5 2.6 0.49 10.3 2.6 1.7 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FTA4 PF13093.6 KIY50687.1 - 0.24 11.3 8.9 0.29 11.0 8.9 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Cauli_AT PF03233.13 KIY50687.1 - 0.43 10.5 2.9 0.59 10.0 1.8 1.6 1 1 1 2 2 2 0 Aphid transmission protein FapA PF03961.13 KIY50687.1 - 0.78 8.3 3.8 0.83 8.2 3.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A PspB PF06667.12 KIY50687.1 - 0.97 9.5 3.7 0.58 10.2 1.5 1.8 1 1 1 2 2 2 0 Phage shock protein B IFP_35_N PF07334.13 KIY50687.1 - 2.5 8.2 7.4 0.12 12.4 1.5 1.8 3 0 0 3 3 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus CCDC-167 PF15188.6 KIY50687.1 - 3.5 8.0 7.8 9.1 6.7 7.8 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4407 PF14362.6 KIY50687.1 - 3.8 6.8 6.3 12 5.1 6.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DEAD PF00270.29 KIY50688.1 - 9.7e-12 45.0 0.0 1.9e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY50688.1 - 7.3e-08 32.7 0.0 3.3e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY50688.1 - 3.5e-06 27.1 0.0 7.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KIY50688.1 - 0.0032 16.8 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain HMG_box_2 PF09011.10 KIY50690.1 - 0.0014 19.2 0.4 0.0044 17.6 0.4 1.9 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KIY50690.1 - 0.1 13.1 0.2 0.29 11.6 0.2 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box DUF3552 PF12072.8 KIY50690.1 - 0.55 9.6 5.9 0.1 12.0 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Sad1_UNC PF07738.13 KIY50691.1 - 6.4e-14 52.1 0.0 7.4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Tet_JBP PF12851.7 KIY50692.1 - 0.089 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF2315 PF10231.9 KIY50693.1 - 0.07 13.2 6.1 0.096 12.8 6.1 1.2 1 0 0 1 1 1 0 Apoptogenic protein 1 KDZ PF18758.1 KIY50694.1 - 1.7e-36 125.9 0.1 2.1e-36 125.6 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIY50695.1 - 4.4e-27 95.2 0.2 8.2e-27 94.3 0.2 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase FTA4 PF13093.6 KIY50695.1 - 3 7.7 10.4 2.3 8.0 1.3 2.8 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Tex_N PF09371.10 KIY50697.1 - 0.24 11.1 0.0 19 4.8 0.0 2.1 1 1 1 2 2 2 0 Tex-like protein N-terminal domain NOA36 PF06524.12 KIY50699.1 - 0.93 8.8 11.9 1.6 7.9 11.9 1.3 1 0 0 1 1 1 0 NOA36 protein gag-asp_proteas PF13975.6 KIY50701.1 - 0.00027 21.4 0.0 0.00074 20.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIY50701.1 - 0.087 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Cbl_N2 PF02761.14 KIY50701.1 - 0.16 12.7 0.0 0.39 11.5 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain Chromo PF00385.24 KIY50704.1 - 0.0057 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain 120_Rick_ant PF12574.8 KIY50705.1 - 0.33 10.1 3.3 3.3 6.8 0.1 2.6 3 0 0 3 3 3 0 120 KDa Rickettsia surface antigen Bac_small_YrzI PF09501.10 KIY50707.1 - 0.049 13.8 0.6 0.11 12.6 0.6 1.6 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) CxC2 PF18803.1 KIY50708.1 - 0.00048 20.3 0.0 0.002 18.3 0.0 1.9 1 1 1 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY50708.1 - 0.12 12.5 0.1 0.36 11.0 0.0 1.8 1 1 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY50709.1 - 3.9e-34 118.2 4.2 8.3e-34 117.1 4.2 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase NPR3 PF03666.13 KIY50709.1 - 0.0024 16.7 1.0 0.023 13.5 1.0 1.9 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 GPW_gp25 PF04965.14 KIY50709.1 - 0.027 14.2 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Gene 25-like lysozyme Antimicrobial12 PF08107.11 KIY50710.1 - 0.075 12.8 0.7 0.095 12.5 0.7 1.3 1 0 0 1 1 1 0 Pleurocidin family TRAF6_Z2 PF18048.1 KIY50716.1 - 0.16 12.1 0.1 0.16 12.1 0.1 1.8 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 PBP1_TM PF14812.6 KIY50718.1 - 0.25 11.8 10.0 0.54 10.7 10.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 KIY50718.1 - 0.28 11.2 1.4 0.45 10.5 1.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KIY50718.1 - 4.6 6.5 5.3 6.6 6.0 5.3 1.2 1 0 0 1 1 1 0 NOA36 protein SNF2_N PF00176.23 KIY50719.1 - 6.4e-42 143.5 0.0 5.8e-31 107.5 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY50719.1 - 3.5e-10 40.2 0.1 8.1e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIY50719.1 - 0.0079 15.4 0.1 0.018 14.2 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase M20_dimer PF07687.14 KIY50720.1 - 8e-08 32.2 0.0 3.2e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KIY50720.1 - 4.7e-06 26.4 0.1 8e-06 25.7 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF836 PF05768.14 KIY50721.1 - 1.1e-11 45.0 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KIY50721.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin AAA_5 PF07728.14 KIY50722.1 - 5.8e-11 42.5 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY50722.1 - 2.2e-07 31.2 0.0 5e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIY50722.1 - 7.2e-07 29.6 0.0 3.3e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIY50722.1 - 2.1e-06 28.2 0.0 5.6e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY50722.1 - 0.00035 21.0 0.0 0.41 11.0 0.1 3.3 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 KIY50722.1 - 0.0035 17.7 0.0 0.022 15.1 0.0 2.2 3 0 0 3 3 3 1 RNA helicase Mg_chelatase PF01078.21 KIY50722.1 - 0.0077 15.6 0.0 0.062 12.7 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KIY50722.1 - 0.028 14.1 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KIY50722.1 - 0.031 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIY50722.1 - 0.038 13.5 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIY50722.1 - 0.079 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KIY50722.1 - 0.18 11.5 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Peptidase_M20 PF01546.28 KIY50723.1 - 1.9e-34 119.2 0.0 3.1e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY50723.1 - 0.00071 19.5 0.0 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY50723.1 - 0.0022 17.7 0.1 0.0046 16.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Sugar_tr PF00083.24 KIY50724.1 - 2.9e-106 356.1 13.5 3.4e-106 355.8 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY50724.1 - 3.5e-26 91.9 49.9 6.4e-25 87.8 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY50724.1 - 0.00027 19.5 1.3 0.00027 19.5 1.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KIY50724.1 - 5.9 7.2 11.1 5.5 7.3 3.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) PhoLip_ATPase_C PF16212.5 KIY50725.1 - 1.1e-66 225.1 28.6 2.6e-66 223.9 28.6 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIY50725.1 - 3.7e-24 84.2 2.7 1.9e-23 82.0 1.7 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIY50725.1 - 1.3e-14 55.0 1.0 1.3e-06 28.8 0.1 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY50725.1 - 6.4e-10 39.0 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KIY50725.1 - 1e-06 28.4 0.0 1e-06 28.4 0.0 2.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIY50725.1 - 1.8e-05 24.6 0.4 0.0025 17.6 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Adeno_E1B_55K_N PF04623.12 KIY50725.1 - 0.12 13.1 0.0 0.37 11.5 0.0 1.9 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus Cation_ATPase_C PF00689.21 KIY50725.1 - 0.31 10.7 12.6 0.27 10.9 4.6 3.0 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus GPI-anchored PF10342.9 KIY50726.1 - 2.1e-07 31.6 1.1 2.5e-07 31.3 1.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family VRR_NUC PF08774.11 KIY50727.1 - 4.1e-19 68.6 0.0 1.1e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain CENP-B_dimeris PF09026.10 KIY50727.1 - 0.64 10.4 0.0 0.64 10.4 0.0 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Zn_clus PF00172.18 KIY50728.1 - 1.8e-08 34.4 12.3 1.8e-08 34.4 12.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KIY50729.1 - 1.4e-43 148.7 1.4 2.1e-43 148.1 0.8 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIY50729.1 - 1.7e-34 118.9 0.1 5.8e-34 117.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIY50729.1 - 1.6e-22 79.5 0.0 3.3e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIY50729.1 - 1.7e-16 60.7 0.7 2.4e-16 60.2 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Phage_GPL PF05926.11 KIY50729.1 - 0.046 13.7 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) Adhesin_Dr PF04619.12 KIY50729.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Dr-family adhesin Pam17 PF08566.10 KIY50730.1 - 4.1e-54 182.9 0.0 4.7e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Ins_P5_2-kin PF06090.12 KIY50731.1 - 1.2e-85 287.9 0.0 1.4e-85 287.7 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-CCHC PF00098.23 KIY50732.1 - 2.5e-05 24.1 0.3 4e-05 23.5 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIY50732.1 - 0.064 13.1 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle ApoL PF05461.11 KIY50734.1 - 0.25 10.6 0.0 0.4 10.0 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein L TPK_catalytic PF04263.16 KIY50735.1 - 2.1e-30 105.2 0.0 2.8e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KIY50735.1 - 4e-18 64.9 0.1 6.1e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain AA_permease PF00324.21 KIY50737.1 - 1.9e-106 356.6 40.6 1.6e-105 353.5 40.6 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY50737.1 - 2e-30 106.0 41.6 7.8e-30 104.0 41.6 1.7 1 1 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KIY50738.1 - 8.4e-108 361.1 22.2 9.8e-108 360.9 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY50738.1 - 3.4e-33 115.0 37.6 2.3e-28 99.2 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY50738.1 - 0.0015 17.1 2.2 0.0015 17.1 2.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PhoLip_ATPase_C PF16212.5 KIY50739.1 - 6e-70 235.8 25.9 6e-70 235.8 25.9 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIY50739.1 - 2.6e-22 78.3 2.2 1.1e-21 76.3 2.2 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIY50739.1 - 5.9e-12 46.3 1.9 9.2e-06 26.1 0.3 4.1 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY50739.1 - 2e-10 40.6 0.0 5.6e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KIY50739.1 - 0.0003 20.4 1.0 0.0016 18.0 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIY50739.1 - 0.0021 17.8 0.2 0.0051 16.6 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1673 PF07895.11 KIY50740.1 - 5.1 6.8 13.4 0.02 14.6 3.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) DASH_Dad3 PF08656.10 KIY50741.1 - 6.4e-19 67.8 0.2 7.3e-19 67.6 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Septin PF00735.18 KIY50742.1 - 1.2e-113 379.1 0.4 1.4e-113 378.9 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIY50742.1 - 4.6e-08 33.1 0.0 9e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIY50742.1 - 6.1e-06 25.7 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIY50742.1 - 6.9e-06 26.1 0.1 6e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KIY50742.1 - 7.5e-05 22.4 0.7 0.0014 18.2 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIY50742.1 - 0.00016 22.1 0.0 0.00058 20.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KIY50742.1 - 0.00028 21.0 0.3 0.81 9.7 0.1 2.4 1 1 1 2 2 2 2 Dynamin family T2SSE PF00437.20 KIY50742.1 - 0.0003 19.9 0.0 0.00068 18.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.22 KIY50742.1 - 0.00037 19.7 0.0 0.00076 18.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain RuvB_N PF05496.12 KIY50742.1 - 0.00075 19.3 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KIY50742.1 - 0.0018 18.8 0.0 0.0035 17.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 KIY50742.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 KIY50742.1 - 0.006 16.1 0.3 0.052 13.1 0.1 2.2 1 1 1 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 KIY50742.1 - 0.0091 16.0 0.1 0.088 12.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 KIY50742.1 - 0.012 15.0 0.1 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KIY50742.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 KIY50742.1 - 0.021 14.5 0.2 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 KIY50742.1 - 0.041 13.6 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KIY50742.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Adeno_IVa2 PF02456.15 KIY50742.1 - 0.066 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_24 PF13479.6 KIY50742.1 - 0.12 12.1 0.4 0.42 10.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIY50742.1 - 0.14 12.6 0.0 0.41 11.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.6 KIY50742.1 - 0.19 11.9 0.3 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 AAA domain Hist_deacetyl PF00850.19 KIY50743.1 - 2.6e-81 273.5 0.1 3.1e-81 273.2 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 KIY50743.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 NIL domain ABC_membrane PF00664.23 KIY50744.1 - 3.8e-103 344.9 25.4 7.8e-56 189.7 10.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY50744.1 - 2.1e-70 235.6 0.0 5.7e-34 117.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY50744.1 - 2.5e-13 50.0 1.8 3.9e-05 23.2 0.0 4.4 4 1 1 5 5 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIY50744.1 - 3.8e-09 35.8 1.6 0.0016 17.3 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KIY50744.1 - 1.6e-08 35.1 2.4 0.00014 22.3 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIY50744.1 - 6.6e-08 32.2 0.4 0.0015 18.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY50744.1 - 7.1e-08 32.8 0.4 0.029 14.6 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KIY50744.1 - 2.7e-05 24.1 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIY50744.1 - 4.2e-05 23.5 1.0 0.66 9.7 0.1 4.0 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KIY50744.1 - 6.7e-05 22.2 0.0 0.25 10.4 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 KIY50744.1 - 9.2e-05 22.4 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 KIY50744.1 - 0.00021 21.3 0.2 0.58 10.2 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIY50744.1 - 0.00045 19.9 2.7 0.33 10.5 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.6 KIY50744.1 - 0.00064 20.3 0.1 0.48 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY50744.1 - 0.00073 19.3 0.8 1.9 8.2 0.2 3.2 2 1 0 2 2 2 2 AAA domain APS_kinase PF01583.20 KIY50744.1 - 0.0014 18.6 0.1 0.48 10.3 0.1 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.29 KIY50744.1 - 0.0017 18.8 3.5 1.2 9.6 0.3 4.4 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KIY50744.1 - 0.0018 17.6 0.1 1.3 8.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 KIY50744.1 - 0.0019 18.7 0.0 3.6 8.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KIY50744.1 - 0.0024 17.6 0.0 0.96 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KIY50744.1 - 0.0032 17.7 4.3 1.9 8.8 0.7 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KIY50744.1 - 0.006 17.0 0.0 3.8 8.0 0.0 4.0 5 0 0 5 5 3 1 RNA helicase AAA_33 PF13671.6 KIY50744.1 - 0.0061 16.7 0.0 6.6 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KIY50744.1 - 0.0073 16.3 0.0 0.34 10.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 KIY50744.1 - 0.0084 15.6 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 KIY50744.1 - 0.009 15.2 0.0 3.5 6.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.17 KIY50744.1 - 0.012 15.7 1.9 2.1 8.4 0.1 3.2 4 0 0 4 4 3 0 Helicase HerA, central domain PRK PF00485.18 KIY50744.1 - 0.015 15.1 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KIY50744.1 - 0.024 13.8 0.2 0.91 8.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KIY50744.1 - 0.033 14.4 4.5 3.2 8.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 KIY50744.1 - 0.058 13.3 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KIY50744.1 - 0.067 13.3 0.0 22 5.2 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF2685 PF10886.8 KIY50744.1 - 0.07 13.3 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF2685) NACHT PF05729.12 KIY50744.1 - 0.089 12.7 0.3 9.4 6.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ABC_membrane PF00664.23 KIY50745.1 - 4e-104 348.1 24.8 1.2e-55 189.1 7.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY50745.1 - 2.4e-70 235.4 0.0 6.8e-34 117.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY50745.1 - 1.2e-13 51.0 0.4 4.3e-05 23.1 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIY50745.1 - 3.8e-09 35.9 1.6 0.0016 17.4 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KIY50745.1 - 1.4e-08 35.3 2.3 0.00011 22.6 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIY50745.1 - 4.4e-08 33.5 0.3 0.016 15.5 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY50745.1 - 5.5e-08 32.4 0.4 0.0015 18.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KIY50745.1 - 6.8e-05 22.7 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY50745.1 - 8.6e-05 22.5 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KIY50745.1 - 0.00011 22.1 1.7 0.65 9.8 0.1 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KIY50745.1 - 0.00015 21.1 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.14 KIY50745.1 - 0.00018 21.5 0.2 0.51 10.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIY50745.1 - 0.00066 19.5 0.8 2 8.1 0.2 3.3 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIY50745.1 - 0.00068 20.2 0.1 0.48 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIY50745.1 - 0.00078 19.9 2.3 0.91 10.0 0.1 4.3 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIY50745.1 - 0.0013 18.7 0.1 0.48 10.3 0.1 2.9 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 KIY50745.1 - 0.0018 17.6 0.1 1.3 8.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 KIY50745.1 - 0.0019 18.7 0.0 3.6 8.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIY50745.1 - 0.0022 17.6 4.4 0.35 10.4 0.1 3.3 4 0 0 4 4 4 2 AAA domain AAA_24 PF13479.6 KIY50745.1 - 0.0027 17.5 0.0 0.95 9.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIY50745.1 - 0.0033 17.7 0.6 3.1 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KIY50745.1 - 0.0039 17.4 4.4 1.9 8.8 0.7 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KIY50745.1 - 0.0068 16.6 0.0 6.5 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIY50745.1 - 0.0081 15.7 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 KIY50745.1 - 0.011 14.9 0.0 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 KIY50745.1 - 0.015 15.4 0.9 2.1 8.4 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KIY50745.1 - 0.019 15.3 0.0 3.4 8.1 0.0 3.2 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.22 KIY50745.1 - 0.023 13.9 0.1 0.87 8.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 KIY50745.1 - 0.024 14.4 0.0 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 KIY50745.1 - 0.033 14.2 0.0 1.5 8.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 KIY50745.1 - 0.085 12.8 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KIY50745.1 - 0.091 12.8 0.0 22 5.2 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 KIY50745.1 - 0.094 12.6 0.4 9.6 6.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KIY50745.1 - 0.095 12.3 0.1 18 4.9 0.0 3.3 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 KIY50745.1 - 0.097 12.0 0.2 6.6 6.0 0.1 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family DUF2685 PF10886.8 KIY50745.1 - 0.11 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) AAA_17 PF13207.6 KIY50745.1 - 0.19 12.2 0.2 38 4.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain Hist_deacetyl PF00850.19 KIY50746.1 - 1.6e-81 274.2 0.0 1.9e-81 273.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 KIY50746.1 - 0.0064 16.3 0.0 0.043 13.7 0.0 2.1 2 0 0 2 2 2 1 NIL domain Peptidase_M16_M PF16187.5 KIY50747.1 - 1.5e-87 293.4 0.4 6.9e-87 291.3 0.0 2.0 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KIY50747.1 - 1e-38 132.6 0.5 3e-38 131.1 0.2 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIY50747.1 - 1.1e-19 71.2 0.0 2.9e-09 37.2 0.0 3.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain WD40 PF00400.32 KIY50749.1 - 1.1e-13 51.4 17.4 0.0047 17.7 0.1 6.6 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY50749.1 - 5.5e-11 42.6 0.1 0.00014 22.1 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 KIY50749.1 - 0.0016 17.3 0.7 0.2 10.4 0.2 3.0 3 0 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 KIY50749.1 - 0.0041 17.0 0.0 0.48 10.3 0.0 3.4 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Rep_fac-A_C PF08646.10 KIY50750.1 - 5.1e-48 162.5 1.4 9.4e-47 158.4 0.4 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KIY50750.1 - 6.2e-31 106.2 0.0 1e-29 102.3 0.0 2.5 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KIY50750.1 - 1.6e-18 66.6 0.1 4.1e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KIY50750.1 - 2.5e-12 46.6 0.2 1e-10 41.4 0.1 2.9 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 KIY50750.1 - 0.00014 22.1 0.1 0.00062 20.0 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function DUF223 DUF4539 PF15072.6 KIY50750.1 - 0.002 18.1 0.0 0.0076 16.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) DUF5521 PF17659.1 KIY50750.1 - 0.002 16.1 0.2 0.29 8.9 0.1 2.9 2 1 0 2 2 2 1 Family of unknown function (DUF5521) CDC24_OB3 PF17244.2 KIY50750.1 - 0.038 13.7 0.4 7.6 6.2 0.1 2.8 2 1 1 3 3 3 0 Cell division control protein 24, OB domain 3 TPP1 PF10341.9 KIY50750.1 - 0.067 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD JAMP PF05571.12 KIY50750.1 - 0.11 12.1 0.3 0.17 11.4 0.3 1.2 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein RuvC_1 PF18516.1 KIY50750.1 - 0.11 11.6 1.1 0.22 10.7 1.1 1.4 1 0 0 1 1 1 0 RuvC nuclease domain DUF829 PF05705.14 KIY50751.1 - 6.2e-38 131.1 0.0 8e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Tim54 PF11711.8 KIY50752.1 - 7e-44 150.1 0.5 8.4e-34 117.0 0.0 3.1 1 1 2 3 3 3 3 Inner membrane protein import complex subunit Tim54 NUDIX PF00293.28 KIY50753.1 - 1.4e-10 41.3 0.0 7.6e-09 35.7 0.0 2.5 1 1 1 2 2 2 1 NUDIX domain NUDIX_4 PF14815.6 KIY50753.1 - 0.027 14.4 0.0 0.068 13.2 0.0 1.6 1 1 0 1 1 1 0 NUDIX domain IDO PF01231.18 KIY50754.1 - 8e-118 394.0 0.0 9.4e-118 393.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Ribosomal_L34 PF00468.17 KIY50754.1 - 0.059 13.3 0.9 0.11 12.4 0.9 1.4 1 0 0 1 1 1 0 Ribosomal protein L34 ECH_2 PF16113.5 KIY50755.1 - 2.8e-109 365.7 0.0 3.3e-109 365.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KIY50755.1 - 1.1e-20 74.0 0.0 1.8e-18 66.8 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase CAP_GLY PF01302.25 KIY50756.1 - 4e-19 68.4 1.0 6.6e-19 67.7 1.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KIY50756.1 - 1.2e-16 60.5 13.9 5e-06 26.8 0.2 5.8 3 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KIY50756.1 - 4.5e-13 49.1 0.2 8.2e-09 35.2 0.0 2.7 1 1 1 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 KIY50756.1 - 6.9e-10 38.5 18.2 4.8e-06 26.2 2.7 5.6 3 2 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.33 KIY50756.1 - 0.1 13.2 20.5 31 5.6 0.0 7.6 7 1 0 7 7 7 0 Leucine Rich Repeat RRM_1 PF00076.22 KIY50757.1 - 1.7e-29 101.4 0.0 8.1e-18 64.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIY50757.1 - 0.00021 21.3 0.0 0.00089 19.2 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIY50757.1 - 0.0013 18.7 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 KIY50757.1 - 0.002 18.2 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 KIY50757.1 - 0.022 14.3 0.0 6 6.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KIY50757.1 - 0.16 11.6 0.1 0.58 9.8 0.1 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Aminotran_5 PF00266.19 KIY50758.1 - 4.3e-92 308.9 0.0 5e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIY50758.1 - 3.7e-07 29.7 0.1 5.5e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KIY50758.1 - 0.048 12.2 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1681 PF07933.14 KIY50759.1 - 2.8e-53 179.6 0.0 3.3e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Rab_eff_C PF04698.12 KIY50759.1 - 0.08 11.2 0.0 0.095 11.0 0.0 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus FAT PF02259.23 KIY50760.1 - 2.4e-106 355.9 3.8 2.4e-106 355.9 3.8 3.0 2 1 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KIY50760.1 - 1e-64 218.7 0.1 2.6e-64 217.4 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KIY50760.1 - 8e-57 191.7 7.1 5e-54 182.6 0.9 4.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KIY50760.1 - 1.5e-39 134.4 0.5 1.5e-39 134.4 0.5 3.7 5 0 0 5 5 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 KIY50760.1 - 2.1e-15 56.9 16.2 0.0011 19.4 0.0 10.9 8 3 5 13 13 13 3 HEAT repeats FATC PF02260.20 KIY50760.1 - 1.8e-14 53.2 1.9 4.3e-14 52.0 1.9 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KIY50760.1 - 2.6e-09 36.5 20.6 0.07 13.4 0.1 12.2 12 0 0 12 12 12 2 HEAT repeat Cnd1 PF12717.7 KIY50760.1 - 2.9e-08 33.9 6.4 0.021 14.9 0.0 5.7 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KIY50760.1 - 8.5e-05 22.2 4.0 14 5.1 0.1 6.0 5 1 1 6 6 6 0 CLASP N terminal HEAT_EZ PF13513.6 KIY50760.1 - 0.00034 21.0 29.7 0.011 16.2 0.3 10.7 12 1 1 13 13 12 1 HEAT-like repeat Adaptin_N PF01602.20 KIY50760.1 - 0.0009 17.9 12.0 1.1 7.7 4.3 5.0 2 1 2 4 4 4 3 Adaptin N terminal region TPR_7 PF13176.6 KIY50760.1 - 0.029 14.4 0.9 0.51 10.5 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat KGG PF10685.9 KIY50760.1 - 0.23 11.8 2.3 18 5.8 0.8 2.9 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif UME PF08064.13 KIY50760.1 - 0.65 9.9 8.7 2.9 7.8 1.3 4.7 4 1 1 5 5 5 0 UME (NUC010) domain Cohesin_HEAT PF12765.7 KIY50760.1 - 1.3 9.4 3.0 4.1 7.8 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion CSN8_PSD8_EIF3K PF10075.9 KIY50761.1 - 0.00013 22.0 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 CSN8/PSMD8/EIF3K family DUF262 PF03235.14 KIY50762.1 - 2.5e-18 67.1 1.4 1.1e-17 64.9 0.2 2.5 1 1 0 2 2 2 1 Protein of unknown function DUF262 MMS22L_C PF14911.6 KIY50762.1 - 2.4e-05 23.6 0.3 4.7e-05 22.6 0.3 1.5 1 1 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal ImcF-related_N PF14331.6 KIY50762.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 ImcF-related N-terminal domain DUF913 PF06025.12 KIY50762.1 - 0.14 11.1 1.5 0.2 10.6 1.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) His_Phos_1 PF00300.22 KIY50763.1 - 2.7e-38 131.6 1.0 5.5e-38 130.6 1.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2368 PF10166.9 KIY50763.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Na_Ca_ex PF01699.24 KIY50764.1 - 4.4e-40 137.1 32.8 4e-23 82.1 12.1 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein ATP_bind_3 PF01171.20 KIY50765.1 - 2.8e-37 128.2 0.0 4.1e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family REV PF00424.18 KIY50765.1 - 0.025 14.6 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) DUF262 PF03235.14 KIY50766.1 - 3.7e-16 60.0 0.5 7.3e-16 59.0 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 Tyr_Deacylase PF02580.16 KIY50767.1 - 6.1e-54 182.5 0.0 7e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase SRP40_C PF05022.12 KIY50768.1 - 9.6e-23 80.8 0.5 9.6e-23 80.8 0.5 1.0 1 0 0 1 1 1 1 SRP40, C-terminal domain DMRL_synthase PF00885.19 KIY50769.1 - 3.2e-56 189.1 0.1 5.3e-56 188.4 0.1 1.3 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase PFU PF09070.11 KIY50770.1 - 3.1e-40 136.9 1.3 5.2e-40 136.2 1.3 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 KIY50770.1 - 5e-36 124.4 0.1 7.2e-36 123.8 0.1 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KIY50770.1 - 2.4e-33 113.6 7.8 1.7e-05 25.5 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 KIY50770.1 - 6.5e-05 22.9 0.0 0.13 12.3 0.0 3.0 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region Gtr1_RagA PF04670.12 KIY50771.1 - 1.8e-82 276.2 0.0 2.5e-82 275.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KIY50771.1 - 4.6e-06 26.3 0.0 7.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY50771.1 - 2.2e-05 24.6 0.0 5.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SKIP_SNW PF02731.15 KIY50772.1 - 5.3e-72 240.7 2.0 5.3e-72 240.7 2.0 2.5 3 0 0 3 3 3 1 SKIP/SNW domain WD40 PF00400.32 KIY50773.1 - 0.017 16.0 6.9 0.52 11.3 0.3 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat PRKG1_interact PF15898.5 KIY50773.1 - 0.037 14.9 0.9 0.085 13.8 0.9 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain WD40_like PF17005.5 KIY50773.1 - 0.16 11.3 0.5 0.53 9.5 0.4 1.7 2 0 0 2 2 2 0 WD40-like domain BBS2_N PF14781.6 KIY50773.1 - 0.2 11.6 0.3 12 5.9 0.0 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.32 KIY50774.1 - 5.4e-57 188.4 20.1 1.9e-09 37.9 0.0 8.3 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY50774.1 - 1.5e-21 76.4 1.0 3.9e-06 27.1 0.0 6.3 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY50774.1 - 4.8e-09 35.4 2.4 0.0021 16.8 0.0 5.5 3 2 3 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIY50774.1 - 0.00042 19.2 0.4 0.46 9.2 0.0 3.6 2 1 2 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 KIY50774.1 - 0.0022 16.6 0.2 0.33 9.4 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 KIY50774.1 - 0.038 13.3 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain bZIP_2 PF07716.15 KIY50774.1 - 0.13 12.3 0.6 0.25 11.4 0.6 1.3 1 0 0 1 1 1 0 Basic region leucine zipper F-box-like PF12937.7 KIY50776.1 - 1.6e-07 31.1 2.4 1.9e-07 30.9 0.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY50776.1 - 0.15 12.0 3.6 0.37 10.7 0.0 3.4 4 0 0 4 4 4 0 F-box domain RNA_pol_N PF01194.17 KIY50777.1 - 3.7e-31 107.2 0.4 5.5e-31 106.7 0.4 1.3 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit adh_short_C2 PF13561.6 KIY50778.1 - 1.9e-54 184.7 1.0 2.3e-54 184.5 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY50778.1 - 1.7e-41 141.8 0.8 2.5e-41 141.3 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY50778.1 - 1e-14 54.8 1.1 1.5e-14 54.3 1.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY50778.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIY50778.1 - 0.00034 19.9 0.1 0.00051 19.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_12 PF08242.12 KIY50778.1 - 0.016 15.9 0.0 0.029 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 KIY50778.1 - 0.057 12.8 0.1 0.096 12.1 0.1 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase PI3_PI4_kinase PF00454.27 KIY50779.1 - 1.5e-32 113.4 0.0 2.8e-30 105.9 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KIY50779.1 - 3.9e-23 81.8 0.0 1.1e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KIY50779.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) WD40 PF00400.32 KIY50781.1 - 6.1e-20 71.2 14.4 7e-06 26.7 0.8 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY50781.1 - 4.7e-05 23.6 0.3 0.0009 19.5 0.1 2.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIY50781.1 - 0.0003 20.6 3.9 0.00075 19.3 3.4 1.9 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIY50781.1 - 0.0083 14.8 0.7 0.015 14.0 0.2 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 IKI3 PF04762.12 KIY50781.1 - 0.037 12.0 0.1 0.38 8.7 0.0 1.9 1 1 1 2 2 2 0 IKI3 family Frtz PF11768.8 KIY50781.1 - 0.08 11.2 0.0 0.14 10.4 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 KIY50781.1 - 0.14 11.2 0.0 0.66 9.0 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region Sybindin PF04099.12 KIY50782.1 - 2.7e-39 134.3 0.0 3.3e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KIY50782.1 - 2.4e-07 30.9 0.0 3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region TATR PF03430.13 KIY50782.1 - 0.14 10.6 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Peptidase_M28 PF04389.17 KIY50783.1 - 1.8e-36 125.7 0.0 6.9e-36 123.8 0.0 2.0 2 1 0 2 2 2 1 Peptidase family M28 C2 PF00168.30 KIY50784.1 - 6.7e-86 283.3 1.5 1.8e-18 66.7 0.0 5.4 5 0 0 5 5 5 5 C2 domain MLVIN_C PF18697.1 KIY50784.1 - 0.0019 18.2 0.2 0.068 13.3 0.0 3.1 3 0 0 3 3 3 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Abhydrolase_1 PF00561.20 KIY50785.1 - 2.1e-10 40.7 0.0 3.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY50785.1 - 0.00012 21.4 0.0 0.00027 20.3 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Pkinase PF00069.25 KIY50787.1 - 2.5e-06 27.0 0.0 0.00034 20.1 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50787.1 - 0.14 11.4 0.0 0.71 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase EcKinase PF02958.20 KIY50787.1 - 0.23 10.7 0.1 0.35 10.1 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase YTH PF04146.15 KIY50788.1 - 2.4e-38 131.7 0.1 4.6e-38 130.8 0.1 1.4 1 1 0 1 1 1 1 YT521-B-like domain Prok-JAB PF14464.6 KIY50788.1 - 0.061 13.1 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain PapG_N PF03627.13 KIY50788.1 - 0.11 12.1 0.0 0.13 12.0 0.0 1.2 1 1 0 1 1 1 0 PapG carbohydrate binding domain Birna_VP3 PF01767.16 KIY50790.1 - 0.36 10.9 4.0 2.3 8.3 4.0 2.1 1 1 0 1 1 1 0 Birnavirus VP3 protein Pkinase PF00069.25 KIY50791.1 - 3e-06 26.8 0.0 0.00029 20.3 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50791.1 - 0.023 14.0 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase zf-C2H2_jaz PF12171.8 KIY50792.1 - 1e-05 25.6 2.2 0.053 13.8 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY50792.1 - 0.0015 18.8 2.2 0.16 12.4 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type HORMA PF02301.18 KIY50793.1 - 7.4e-63 212.0 0.0 1.2e-62 211.2 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KIY50793.1 - 9.7e-05 22.2 10.5 0.00019 21.3 10.5 1.5 1 0 0 1 1 1 1 PHD-finger CBM-like PF14683.6 KIY50794.1 - 8.5e-27 94.0 2.3 2.1e-26 92.8 0.7 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KIY50794.1 - 2e-24 85.2 0.8 6.3e-24 83.6 0.8 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KIY50794.1 - 0.0013 18.9 1.2 0.003 17.8 0.5 2.0 1 1 1 2 2 2 1 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.13 KIY50794.1 - 0.03 14.3 0.2 0.11 12.5 0.2 1.9 1 0 0 1 1 1 0 Y_Y_Y domain HMGL-like PF00682.19 KIY50795.1 - 5.8e-75 252.3 0.0 1e-74 251.4 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KIY50795.1 - 2.1e-43 147.4 0.3 2.1e-20 73.0 0.0 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain HA2 PF04408.23 KIY50796.1 - 1.4e-25 89.6 0.6 4.2e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY50796.1 - 3.3e-24 85.0 0.0 6.8e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY50796.1 - 2.1e-13 50.6 0.0 6.7e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KIY50796.1 - 5.8e-10 39.4 0.3 1.7e-09 37.9 0.3 1.8 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 KIY50796.1 - 0.0001 22.6 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KIY50796.1 - 0.0005 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KIY50796.1 - 0.00064 18.9 0.0 0.0017 17.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KIY50796.1 - 0.0026 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIY50796.1 - 0.003 18.1 0.7 1.7 9.1 0.0 3.4 2 2 1 3 3 3 1 ABC transporter DUF2075 PF09848.9 KIY50796.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KIY50796.1 - 0.031 14.6 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIY50796.1 - 0.13 11.6 0.0 0.38 10.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein EF-hand_4 PF12763.7 KIY50797.1 - 0.0063 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KIY50797.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 EF hand APG9 PF04109.16 KIY50798.1 - 2.1e-209 696.5 12.5 2.4e-209 696.3 12.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Thiamine_BP PF01910.17 KIY50799.1 - 6.8e-22 77.2 0.0 1.1e-21 76.6 0.0 1.4 1 1 0 1 1 1 1 Thiamine-binding protein ApbA_C PF08546.11 KIY50799.1 - 0.11 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF4681 PF15732.5 KIY50802.1 - 0.058 13.7 1.3 4 7.7 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4681) 23S_rRNA_IVP PF05635.11 KIY50802.1 - 0.2 12.0 0.6 0.37 11.1 0.6 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein DUF1776 PF08643.10 KIY50805.1 - 1.1e-13 51.2 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Arginase PF00491.21 KIY50805.1 - 0.05 13.1 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Arginase family CPDase PF07823.11 KIY50806.1 - 1.6e-17 63.9 0.7 1.7e-16 60.5 0.7 2.1 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KIY50806.1 - 5.3e-09 36.2 0.2 7.6e-09 35.6 0.2 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KIY50806.1 - 0.0045 17.1 0.3 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 LigT like Phosphoesterase MFS_1 PF07690.16 KIY50808.1 - 4.4e-08 32.5 16.4 4.4e-08 32.5 16.4 2.1 2 1 1 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY50808.1 - 0.017 14.9 2.8 0.036 13.8 0.4 2.5 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Peptidase_S8 PF00082.22 KIY50809.1 - 1.3e-36 126.5 3.0 1.8e-36 125.9 3.0 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KIY50809.1 - 2e-25 88.6 0.2 4e-25 87.7 0.2 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 KIY50809.1 - 0.0079 16.7 0.1 0.078 13.5 0.1 2.2 1 1 0 1 1 1 1 N-terminal of Subtilase family XhlA PF10779.9 KIY50809.1 - 0.2 11.9 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Haemolysin XhlA RdRP PF05183.12 KIY50810.1 - 2.4e-166 554.9 0.0 3e-166 554.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Glyco_hydro_71 PF03659.14 KIY50811.1 - 4.7e-109 364.6 12.2 5.3e-109 364.5 12.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 POT1PC PF16686.5 KIY50812.1 - 4.4e-21 75.4 3.8 5.2e-11 42.7 0.2 3.8 2 2 0 2 2 2 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KIY50812.1 - 1.4e-07 31.4 0.0 3.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Rep_fac-A_C PF08646.10 KIY50812.1 - 0.066 12.9 0.3 0.16 11.7 0.3 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain Methyltransf_PK PF05891.12 KIY50813.1 - 4.7e-47 160.3 0.0 2.1e-46 158.2 0.0 1.9 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KIY50813.1 - 2.8e-07 31.1 0.0 0.00011 22.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY50813.1 - 5.1e-06 27.0 0.0 4.2e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY50813.1 - 0.00021 22.0 0.0 0.00083 20.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY50813.1 - 0.0023 17.8 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KIY50813.1 - 0.062 12.4 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ADK PF00406.22 KIY50814.1 - 3.8e-43 147.2 0.0 4.9e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIY50814.1 - 4.4e-19 69.3 0.0 7.5e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KIY50814.1 - 5.7e-14 51.8 0.0 9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KIY50814.1 - 1.3e-05 25.8 0.0 2.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY50814.1 - 0.009 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 KIY50814.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Hydin_ADK PF17213.3 KIY50814.1 - 0.21 11.8 0.4 1.4 9.1 0.0 2.1 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Trm112p PF03966.16 KIY50815.1 - 6.3e-21 74.7 0.1 9.1e-21 74.2 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein zf-ribbon_3 PF13248.6 KIY50815.1 - 0.0065 15.8 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KIY50815.1 - 0.017 15.1 0.3 0.031 14.2 0.3 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.6 KIY50815.1 - 0.026 14.2 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RNase_PH PF01138.21 KIY50816.1 - 2.8e-19 69.9 0.0 4.5e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIY50816.1 - 1.4e-07 31.4 0.1 3e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Pkinase PF00069.25 KIY50817.1 - 1.1e-42 146.2 0.0 1.3e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50817.1 - 1.5e-18 67.1 0.0 2.6e-18 66.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY50817.1 - 0.0012 18.2 0.0 0.004 16.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KIY50817.1 - 0.0098 15.5 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KIY50817.1 - 0.069 12.1 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KIY50817.1 - 0.11 11.6 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KIY50817.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Transket_pyr PF02779.24 KIY50818.1 - 3.8e-39 134.2 0.0 6.1e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIY50818.1 - 2.8e-26 91.8 0.0 1.1e-25 89.9 0.0 2.0 2 1 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.32 KIY50819.1 - 3.1e-09 37.3 12.6 0.0034 18.2 0.1 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY50819.1 - 5.2e-05 23.5 0.0 0.23 11.8 0.0 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIY50819.1 - 0.0044 15.6 0.0 0.011 14.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 KIY50819.1 - 0.0085 16.0 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A YpsA PF06908.11 KIY50819.1 - 0.091 12.8 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 YspA SLOG family Med21 PF11221.8 KIY50820.1 - 1.8e-24 86.7 9.4 2.5e-24 86.2 9.4 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex BRE1 PF08647.11 KIY50820.1 - 0.013 15.5 0.8 0.013 15.5 0.8 2.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase CSN7a_helixI PF18392.1 KIY50820.1 - 0.016 15.1 0.2 0.048 13.6 0.2 1.9 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain LOH1CR12 PF10158.9 KIY50820.1 - 0.023 14.7 4.2 1.5 8.8 0.1 2.5 2 1 0 2 2 2 0 Tumour suppressor protein DUF3290 PF11694.8 KIY50820.1 - 0.026 14.5 0.1 0.039 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Metal_resist PF13801.6 KIY50820.1 - 0.032 14.4 1.9 0.032 14.4 1.9 1.8 2 0 0 2 2 2 0 Heavy-metal resistance DUF4806 PF16064.5 KIY50820.1 - 0.12 12.7 0.8 3.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) SseC PF04888.12 KIY50820.1 - 1.4 8.4 6.4 8.9 5.8 1.5 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family CENP-H PF05837.12 KIY50820.1 - 5.5 7.4 7.3 7.4 7.0 2.5 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ABC_tran_CTD PF16326.5 KIY50820.1 - 8.3 6.7 14.1 2.1 8.7 1.3 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain MCM PF00493.23 KIY50821.1 - 4.4e-105 349.7 0.0 7.5e-105 349.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY50821.1 - 4.9e-30 104.0 0.1 8.3e-30 103.2 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY50821.1 - 1.5e-19 70.2 1.1 3.2e-19 69.1 1.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIY50821.1 - 2.5e-08 34.5 0.1 2.9e-06 27.8 0.1 2.8 1 1 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 KIY50821.1 - 6.5e-08 32.7 0.0 5.9e-06 26.3 0.0 3.2 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIY50821.1 - 9.4e-08 31.7 0.1 9.8e-06 25.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 KIY50821.1 - 0.0002 22.0 0.8 0.00053 20.6 0.4 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KIY50821.1 - 0.018 14.9 0.0 0.053 13.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KIY50821.1 - 0.023 14.5 0.1 0.084 12.7 0.1 1.9 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 KIY50821.1 - 0.14 11.9 0.0 0.62 9.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_methylase PF00145.17 KIY50822.1 - 2.6e-50 171.7 0.0 4.8e-50 170.8 0.0 1.4 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 KIY50822.1 - 0.0023 18.0 0.0 0.0059 16.6 0.0 1.8 1 1 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 KIY50822.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 BAH domain SDA1 PF05285.12 KIY50823.1 - 0.23 10.8 21.4 0.28 10.6 21.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KIY50823.1 - 3.3 7.0 23.2 4 6.7 23.2 1.1 1 0 0 1 1 1 0 BUD22 Ras PF00071.22 KIY50824.1 - 4.9e-59 198.6 0.3 6.2e-59 198.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY50824.1 - 4e-37 127.1 0.1 7.6e-37 126.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY50824.1 - 3.3e-16 59.2 0.1 4.1e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIY50824.1 - 9e-07 28.5 0.1 1.6e-06 27.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY50824.1 - 6.1e-06 25.8 0.3 7.6e-06 25.4 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY50824.1 - 6.9e-06 25.7 0.3 0.00016 21.2 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY50824.1 - 1.8e-05 24.8 0.1 5.6e-05 23.2 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY50824.1 - 0.00025 21.0 0.0 0.069 13.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIY50824.1 - 0.0033 17.0 0.3 0.21 11.1 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KIY50824.1 - 0.019 14.7 1.2 0.17 11.6 1.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KIY50824.1 - 0.044 13.9 0.0 2.1 8.3 0.0 2.6 2 1 1 3 3 3 0 Dynamin family TniB PF05621.11 KIY50824.1 - 0.073 12.5 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 KIY50824.1 - 0.082 13.3 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TAP42 PF04177.12 KIY50826.1 - 1e-84 284.4 0.3 1.2e-84 284.2 0.3 1.0 1 0 0 1 1 1 1 TAP42-like family Apis_Csd PF11671.8 KIY50826.1 - 0.15 12.0 1.1 0.3 11.1 1.1 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Pap_E4 PF02711.14 KIY50826.1 - 2.8 9.0 5.6 4.5 8.3 0.6 2.5 2 0 0 2 2 2 0 E4 protein Glyco_hydro81C PF17652.1 KIY50828.1 - 1.8e-70 237.9 4.4 2.7e-70 237.4 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KIY50828.1 - 2e-29 102.8 1.1 4.7e-29 101.6 1.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Fascin PF06268.13 KIY50828.1 - 0.056 13.7 0.0 0.19 12.0 0.0 1.8 1 1 1 2 2 2 0 Fascin domain 3HCDH_RFF PF18321.1 KIY50828.1 - 0.11 12.9 0.1 0.4 11.2 0.1 1.9 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Pyr_redox_2 PF07992.14 KIY50830.1 - 1.4e-44 152.5 0.0 2.2e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY50830.1 - 5.5e-10 39.7 0.0 2e-07 31.4 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KIY50830.1 - 1.2e-07 30.7 1.0 0.0087 15.5 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KIY50830.1 - 8.6e-07 28.4 0.4 0.012 15.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KIY50830.1 - 6.6e-06 26.5 0.1 1.7e-05 25.2 0.2 1.8 1 1 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 KIY50830.1 - 0.0017 17.6 0.8 2 7.6 0.0 3.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ParE_toxin PF05016.15 KIY50830.1 - 0.088 13.4 0.3 0.91 10.2 0.1 2.8 4 0 0 4 4 4 0 ParE toxin of type II toxin-antitoxin system, parDE EF-hand_5 PF13202.6 KIY50830.1 - 0.14 11.7 1.3 0.53 9.9 0.3 2.3 2 0 0 2 2 2 0 EF hand ATP-synt_ab PF00006.25 KIY50831.1 - 6.4e-30 104.4 0.0 1.1e-29 103.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 KIY50831.1 - 0.15 12.0 0.9 0.86 9.5 0.9 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATP-synt_ab PF00006.25 KIY50832.1 - 1.6e-63 214.2 0.0 2.3e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KIY50832.1 - 0.0022 17.2 0.8 0.007 15.6 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 KIY50832.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KIY50832.1 - 0.017 15.0 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KIY50832.1 - 0.017 15.5 0.1 0.056 13.8 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 KIY50832.1 - 0.019 14.9 0.0 0.049 13.5 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIY50832.1 - 0.02 15.3 0.0 0.34 11.3 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KIY50832.1 - 0.041 13.2 0.2 0.075 12.4 0.2 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KIY50832.1 - 0.043 14.2 0.7 0.19 12.0 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIY50832.1 - 0.1 12.9 0.2 0.33 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIY50832.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KIY50832.1 - 0.12 12.9 0.4 0.35 11.4 0.2 1.8 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KIY50832.1 - 0.14 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region T3SS_ATPase_C PF18269.1 KIY50832.1 - 0.26 11.1 0.9 1.4 8.9 0.9 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Hydrophobin PF01185.18 KIY50833.1 - 6.8e-12 45.8 6.2 1e-11 45.3 6.2 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIY50834.1 - 8.3e-10 39.2 8.1 1.1e-09 38.8 8.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin zf-RING_5 PF14634.6 KIY50835.1 - 0.048 13.6 1.3 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-MIZ PF02891.20 KIY50835.1 - 0.11 12.2 0.2 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Zn_ribbon_SprT PF17283.2 KIY50835.1 - 0.15 12.0 0.9 0.71 9.8 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain CxC4 PF18717.1 KIY50835.1 - 0.17 11.7 0.1 19 5.1 0.0 2.2 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases DUF2418 PF10332.9 KIY50836.1 - 4e-28 97.8 0.1 6.8e-28 97.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) 4HBT PF03061.22 KIY50837.1 - 1.2e-08 35.1 0.0 2.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF3084 PF11283.8 KIY50837.1 - 0.015 15.3 0.6 0.073 13.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) Hydrophobin PF01185.18 KIY50838.1 - 5e-15 55.9 8.5 6.1e-15 55.6 8.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin AAA PF00004.29 KIY50839.1 - 2.2e-15 57.2 0.0 6.4e-15 55.7 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIY50839.1 - 2.1e-06 27.8 0.0 7.7e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KIY50839.1 - 2.4e-06 27.4 0.1 1.1e-05 25.2 0.0 2.1 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIY50839.1 - 3.4e-05 24.3 0.0 0.0049 17.3 0.0 2.9 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KIY50839.1 - 0.00023 21.2 0.0 0.00079 19.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KIY50839.1 - 0.00047 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY50839.1 - 0.0016 18.6 0.0 0.0043 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KIY50839.1 - 0.0018 18.5 0.0 0.0049 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_18 PF13238.6 KIY50839.1 - 0.0055 17.3 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIY50839.1 - 0.0056 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KIY50839.1 - 0.0056 16.9 0.1 0.081 13.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY50839.1 - 0.0078 15.8 0.3 0.1 12.1 0.0 2.6 2 1 1 3 3 3 1 AAA domain DevR PF01905.16 KIY50839.1 - 0.0091 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 CRISPR-associated negative auto-regulator DevR/Csa2 AAA_28 PF13521.6 KIY50839.1 - 0.0091 16.3 0.0 0.071 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KIY50839.1 - 0.011 15.6 0.0 0.031 14.2 0.0 1.7 1 1 1 2 2 2 0 NTPase NACHT PF05729.12 KIY50839.1 - 0.014 15.4 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 0 NACHT domain OrsD PF12013.8 KIY50839.1 - 0.03 14.7 0.0 0.08 13.4 0.0 1.7 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D AAA_17 PF13207.6 KIY50839.1 - 0.061 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIY50839.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 KIY50839.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NB-ARC PF00931.22 KIY50839.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 KIY50839.1 - 0.19 10.9 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Prenyltrans PF00432.21 KIY50840.1 - 2.7e-56 186.9 5.4 8.9e-12 44.5 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KIY50840.1 - 0.0018 17.4 0.0 0.0048 16.0 0.0 1.6 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain DUF4472 PF14739.6 KIY50841.1 - 0.024 15.4 1.4 0.024 15.4 1.4 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) DUF3365 PF11845.8 KIY50841.1 - 0.038 14.3 0.3 0.089 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) DUF948 PF06103.11 KIY50841.1 - 0.78 10.0 5.5 0.83 10.0 0.4 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CAMSAP_CC1 PF17095.5 KIY50841.1 - 1 9.2 7.9 11 6.0 1.8 2.8 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin DUF724 PF05266.14 KIY50841.1 - 1.3 8.8 17.0 0.047 13.5 1.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 KIY50841.1 - 2.1 8.5 21.7 0.029 14.6 2.3 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Gon7 PF08738.10 KIY50841.1 - 2.3 8.3 11.2 6.1 7.0 0.5 3.4 2 1 0 3 3 3 0 Gon7 family YabA PF06156.13 KIY50841.1 - 2.7 8.7 11.9 1.4 9.6 0.8 3.1 3 0 0 3 3 3 0 Initiation control protein YabA FlaC_arch PF05377.11 KIY50841.1 - 3.5 8.1 9.1 1.8 9.0 0.2 4.2 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 KIY50841.1 - 6.7 6.9 28.8 2e+02 2.1 0.9 3.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HalX PF08663.10 KIY50842.1 - 0.057 13.7 0.9 0.65 10.4 0.1 2.4 2 0 0 2 2 2 0 HalX domain SRA1 PF07304.11 KIY50842.1 - 0.063 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DUF3552 PF12072.8 KIY50843.1 - 0.00085 18.8 4.9 0.025 14.0 1.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) DUF2721 PF11026.8 KIY50843.1 - 0.0075 16.2 0.3 0.0075 16.2 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) Lzipper-MIP1 PF14389.6 KIY50843.1 - 0.12 12.7 1.1 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1090 PF06476.12 KIY50843.1 - 3.3 7.8 5.7 17 5.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) MFS_1 PF07690.16 KIY50844.1 - 6.4e-27 94.4 30.1 2.5e-26 92.5 30.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM135_C_rich PF15982.5 KIY50844.1 - 0.0066 17.1 1.6 0.014 16.0 0.4 2.2 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 CLP1_P PF16575.5 KIY50845.1 - 2.9e-35 121.8 0.0 2.1e-34 119.0 0.0 2.3 2 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KIY50845.1 - 3.8e-30 103.9 0.0 6.2e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KIY50845.1 - 4.8e-27 94.7 0.0 8.7e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 gag_pre-integrs PF13976.6 KIY50845.1 - 0.0016 18.2 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain ATP_bind_1 PF03029.17 KIY50845.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA PF00004.29 KIY50845.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIY50845.1 - 0.18 12.3 0.0 0.54 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KIY50845.1 - 0.19 11.1 0.0 0.52 9.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein KH_9 PF17904.1 KIY50847.1 - 0.05 14.0 0.2 11 6.5 0.0 2.6 2 0 0 2 2 2 0 FMRP KH0 domain MscS_porin PF12795.7 KIY50847.1 - 0.051 13.1 11.3 0.09 12.3 11.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF496 PF04363.12 KIY50847.1 - 0.11 12.5 0.5 0.2 11.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF496) Rootletin PF15035.6 KIY50847.1 - 1.1 9.3 12.8 45 4.0 12.3 2.7 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Tropomyosin_1 PF12718.7 KIY50847.1 - 1.4 9.0 5.5 0.66 10.1 0.5 2.2 1 1 1 2 2 2 0 Tropomyosin like PRKG1_interact PF15898.5 KIY50847.1 - 3.4 8.6 8.8 5.8 7.9 6.2 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain HIP1_clath_bdg PF16515.5 KIY50847.1 - 5.3 7.7 13.4 3.2 8.4 4.5 3.6 2 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GCIP PF13324.6 KIY50848.1 - 3.4e-39 135.0 0.4 4.2e-39 134.7 0.4 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Peptidase_M41 PF01434.18 KIY50849.1 - 4.2e-51 173.5 2.1 1.9e-50 171.4 2.1 1.9 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KIY50849.1 - 3.3e-44 150.5 0.0 1e-43 148.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY50849.1 - 1.8e-10 40.4 0.0 4.2e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KIY50849.1 - 1.8e-05 24.1 0.0 0.00016 21.0 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 KIY50849.1 - 3.1e-05 24.4 0.9 0.001 19.5 0.9 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIY50849.1 - 4.7e-05 23.4 0.1 0.00026 21.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIY50849.1 - 0.00013 21.8 0.0 0.00037 20.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIY50849.1 - 0.00075 19.8 0.5 0.098 12.9 0.0 3.0 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KIY50849.1 - 0.0056 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY50849.1 - 0.0071 16.9 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KIY50849.1 - 0.0082 15.7 0.7 0.36 10.4 0.2 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KIY50849.1 - 0.0097 15.3 0.4 0.021 14.2 0.4 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KIY50849.1 - 0.016 14.6 0.1 1 8.6 0.0 2.3 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 KIY50849.1 - 0.016 15.0 0.0 0.044 13.5 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 KIY50849.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 KIY50849.1 - 0.022 15.0 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIY50849.1 - 0.029 14.3 0.1 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KIY50849.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KIY50849.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KIY50849.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain TPR_12 PF13424.6 KIY50850.1 - 1.2e-06 28.7 0.6 0.59 10.5 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY50850.1 - 0.0037 17.3 8.0 0.18 12.0 0.1 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY50850.1 - 0.0055 16.8 1.9 7.6 7.0 0.1 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY50850.1 - 0.0087 16.6 4.5 12 6.5 0.1 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY50850.1 - 0.0098 16.6 10.8 16 6.7 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIY50850.1 - 0.011 15.6 0.3 11 6.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIY50850.1 - 0.049 13.3 1.4 4.2 7.1 0.0 3.9 5 0 0 5 5 5 0 TPR repeat TPR_4 PF07721.14 KIY50850.1 - 0.086 13.5 0.0 0.9 10.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY50850.1 - 0.15 11.9 4.7 1.7 8.6 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY50850.1 - 0.26 12.0 5.9 11 6.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C14 PF00656.22 KIY50851.1 - 3.5e-47 161.4 0.0 4.2e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Caspase domain F-box-like PF12937.7 KIY50852.1 - 8.3e-05 22.4 0.6 8.3e-05 22.4 0.6 1.9 2 0 0 2 2 2 1 F-box-like tRNA-synt_2d PF01409.20 KIY50853.1 - 4.8e-43 147.4 0.0 5.3e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KIY50853.1 - 0.00073 19.9 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain FBPase PF00316.20 KIY50854.1 - 5.2e-73 244.6 0.4 6.6e-73 244.2 0.4 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KIY50854.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 Inositol monophosphatase family Pmp3 PF01679.17 KIY50856.1 - 3.7e-17 62.3 3.0 5e-17 61.8 3.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.8 KIY50856.1 - 0.078 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal zf-C2H2 PF00096.26 KIY50857.1 - 1.4e-12 47.4 13.6 7.1e-07 29.3 3.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY50857.1 - 6.8e-10 38.9 16.2 2.2e-08 34.2 3.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY50857.1 - 6.3e-09 35.9 10.3 0.00028 21.5 1.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY50857.1 - 1e-06 28.9 0.4 0.0038 17.5 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KIY50857.1 - 4.4e-06 27.2 2.1 0.016 15.8 0.1 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KIY50857.1 - 0.0028 17.9 0.8 0.0052 17.1 0.8 1.4 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KIY50857.1 - 0.0032 17.4 9.2 0.022 14.8 0.2 2.6 2 1 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KIY50857.1 - 0.0045 17.3 3.8 0.036 14.5 0.1 2.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KIY50857.1 - 0.0075 16.0 9.5 0.65 9.8 5.2 2.7 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-CGNR PF11706.8 KIY50857.1 - 0.09 12.6 4.1 2 8.3 0.7 2.3 2 0 0 2 2 2 0 CGNR zinc finger zf-C2H2_aberr PF17017.5 KIY50857.1 - 0.33 11.1 2.0 12 6.0 0.1 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger Toxin_8 PF07365.12 KIY50857.1 - 1.5 9.1 5.6 2.3 8.5 1.2 2.2 2 0 0 2 2 2 0 Alpha conotoxin precursor PNGaseA PF12222.8 KIY50858.1 - 3.3e-132 441.4 6.6 4.6e-132 440.9 6.6 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A FTHFS PF01268.19 KIY50859.1 - 1.5e-255 848.7 0.5 2.6e-255 847.9 0.0 1.6 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KIY50859.1 - 6.9e-64 214.0 0.8 6.9e-64 214.0 0.8 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KIY50859.1 - 5.7e-36 123.3 0.1 1.3e-35 122.1 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Helicase_C_4 PF13871.6 KIY50859.1 - 0.0098 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue OCD_Mu_crystall PF02423.15 KIY50859.1 - 0.032 13.2 0.3 0.072 12.0 0.3 1.5 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GrpE PF01025.19 KIY50860.1 - 3.4e-42 143.9 0.0 6.5e-42 143.0 0.0 1.5 1 1 0 1 1 1 1 GrpE Phosphorylase PF00343.20 KIY50861.1 - 1.4e-298 992.2 0.0 1.6e-298 992.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase ox_reductase_C PF08635.10 KIY50862.1 - 6e-69 230.2 0.1 8.9e-69 229.6 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 KIY50862.1 - 3.9e-24 85.8 0.0 7.8e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIY50862.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Heme_oxygenase PF01126.20 KIY50863.1 - 0.0014 18.4 0.3 0.0018 18.1 0.3 1.2 1 0 0 1 1 1 1 Heme oxygenase Sipho_Gp157 PF05565.11 KIY50863.1 - 0.0038 17.3 3.2 0.005 16.9 3.2 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 SKA2 PF16740.5 KIY50863.1 - 0.016 15.0 4.6 0.028 14.2 4.6 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Rx_N PF18052.1 KIY50863.1 - 0.027 14.7 3.8 0.042 14.1 3.8 1.3 1 0 0 1 1 1 0 Rx N-terminal domain YabA PF06156.13 KIY50863.1 - 0.11 13.1 2.2 0.17 12.5 2.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA SecD-TM1 PF13721.6 KIY50863.1 - 0.79 10.2 4.0 1.2 9.7 1.3 2.0 1 1 1 2 2 2 0 SecD export protein N-terminal TM region UPF0242 PF06785.11 KIY50863.1 - 2.9 8.0 8.3 1.3 9.1 6.6 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EMC3_TMCO1 PF01956.16 KIY50863.1 - 6 6.6 4.8 8 6.2 4.8 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PIG-Y PF15159.6 KIY50864.1 - 1.2e-17 64.5 11.2 1.4e-17 64.3 11.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PSI_PsaF PF02507.15 KIY50864.1 - 0.038 13.8 1.0 0.049 13.5 1.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Tetraspanin PF00335.20 KIY50864.1 - 0.13 12.0 3.2 0.15 11.8 3.2 1.0 1 0 0 1 1 1 0 Tetraspanin family Glyco_hydro_92 PF07971.12 KIY50865.1 - 1.6e-94 317.4 0.1 6.1e-94 315.5 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIY50865.1 - 1.5e-47 162.5 0.0 3.5e-47 161.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Sfi1 PF08457.10 KIY50867.1 - 1.4e-22 80.0 115.2 1.4e-15 56.9 66.5 5.1 1 1 4 5 5 5 5 Sfi1 spindle body protein zf-C2HE PF16278.5 KIY50868.1 - 2.2e-15 56.8 0.0 4.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KIY50868.1 - 3e-11 43.8 0.0 5.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIY50868.1 - 5.3e-07 30.3 0.0 1.5e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 HIT domain zf-C2H2_2 PF12756.7 KIY50868.1 - 0.0086 16.4 0.7 0.056 13.8 0.0 2.2 1 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Dynein_light PF01221.18 KIY50868.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Dynein light chain type 1 PAP2 PF01569.21 KIY50869.1 - 4e-15 55.8 7.1 5.8e-15 55.2 7.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KIY50869.1 - 0.017 15.2 0.9 0.33 11.1 0.2 2.2 1 1 1 2 2 2 0 Divergent PAP2 family DUF4131 PF13567.6 KIY50869.1 - 0.12 12.1 1.6 0.36 10.5 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Phage_holin_3_1 PF05106.12 KIY50869.1 - 0.14 12.6 0.8 0.44 11.0 0.2 1.9 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) RabGAP-TBC PF00566.18 KIY50870.1 - 8.1e-40 136.8 6.9 5.6e-38 130.8 1.5 2.3 1 1 1 2 2 2 2 Rab-GTPase-TBC domain SET PF00856.28 KIY50871.1 - 8.5e-10 39.3 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KIY50871.1 - 0.18 12.5 0.0 0.32 11.7 0.0 1.3 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding adh_short PF00106.25 KIY50872.1 - 2.7e-46 157.5 0.3 5.5e-46 156.5 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY50872.1 - 3.2e-28 98.9 0.3 5.7e-28 98.1 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY50872.1 - 9.4e-07 28.9 0.1 1.2e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY50872.1 - 8.2e-05 22.2 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIY50872.1 - 0.0095 15.3 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KIY50872.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KIY50872.1 - 0.036 13.3 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Eno-Rase_NADH_b PF12242.8 KIY50872.1 - 0.068 12.9 1.0 0.15 11.9 1.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ssDNA-exonuc_C PF10141.9 KIY50874.1 - 0.2 11.3 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain Acyltransferase PF01553.21 KIY50875.1 - 6.1e-13 48.6 0.0 7.4e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Peptidase_M24 PF00557.24 KIY50876.1 - 6.8e-52 176.2 0.0 8.8e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KIY50876.1 - 9.8e-15 54.6 9.7 1.6e-14 53.9 9.7 1.3 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding CEBP_ZZ PF16366.5 KIY50876.1 - 0.012 15.8 1.8 0.028 14.6 1.8 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Pectate_lyase_3 PF12708.7 KIY50878.1 - 3.1e-96 321.3 15.4 4.1e-85 285.0 9.0 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIY50878.1 - 1.8e-06 27.5 0.6 0.0091 15.7 0.1 3.0 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 KIY50878.1 - 0.00025 20.9 2.1 0.00025 20.9 2.1 2.5 2 1 1 3 3 3 1 Right handed beta helix region IF-2B PF01008.17 KIY50879.1 - 1.8e-60 204.6 0.0 2.5e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family PNTB PF02233.16 KIY50879.1 - 0.0036 16.3 0.2 0.0047 15.9 0.2 1.1 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit Cyclin_N PF00134.23 KIY50880.1 - 1.5e-11 44.1 0.7 2.3e-11 43.5 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY50880.1 - 3.8e-05 23.8 0.8 0.031 14.4 0.1 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.19 KIY50880.1 - 0.004 17.2 0.2 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KIY50880.1 - 0.05 14.0 0.3 0.49 10.8 0.0 2.5 3 1 0 3 3 3 0 Cyclin C-terminal domain RWD PF05773.22 KIY50883.1 - 5.7e-19 68.5 0.2 1.8e-18 66.9 0.1 1.9 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KIY50883.1 - 1.5e-05 25.4 15.9 0.00029 21.3 15.6 2.7 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Ribosomal_S21 PF01165.20 KIY50884.1 - 1.5e-10 40.6 1.1 2.6e-10 39.9 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Abhydrolase_1 PF00561.20 KIY50885.1 - 8e-07 29.0 0.1 0.00011 22.0 0.1 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY50885.1 - 0.00051 19.4 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 ARGLU PF15346.6 KIY50886.1 - 0.0045 16.9 18.5 0.0045 16.9 18.5 3.4 3 2 0 3 3 3 1 Arginine and glutamate-rich 1 Amnionless PF14828.6 KIY50888.1 - 0.15 10.9 6.0 0.19 10.6 5.2 1.5 1 1 0 1 1 1 0 Amnionless PPP4R2 PF09184.11 KIY50888.1 - 1.5 8.3 10.7 2.5 7.6 10.7 1.4 1 0 0 1 1 1 0 PPP4R2 Utp14 PF04615.13 KIY50888.1 - 1.8 7.0 8.5 2.4 6.6 8.5 1.1 1 0 0 1 1 1 0 Utp14 protein RIFIN PF02009.16 KIY50888.1 - 2.7 7.8 11.3 5.9 6.7 11.3 1.5 1 0 0 1 1 1 0 Rifin Vmethyltransf_C PF08456.10 KIY50888.1 - 8.1 6.0 7.6 12 5.4 7.6 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal CLASP_N PF12348.8 KIY50890.1 - 1.9e-17 63.6 0.0 7.8e-07 28.9 0.0 4.8 5 0 0 5 5 5 4 CLASP N terminal Cnd1 PF12717.7 KIY50890.1 - 6.3e-11 42.6 0.3 0.093 12.8 0.0 7.5 6 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIY50890.1 - 1.9e-09 36.9 22.9 0.12 12.7 0.0 11.6 13 0 0 13 13 12 2 HEAT repeat HEAT_2 PF13646.6 KIY50890.1 - 6.1e-06 26.5 24.6 0.49 10.8 0.0 9.7 9 2 1 11 11 11 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KIY50890.1 - 0.0014 19.2 0.0 3.4 8.3 0.0 5.2 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Nipped-B_C PF12830.7 KIY50890.1 - 0.0021 18.1 0.0 3.2 7.7 0.0 3.1 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 KIY50890.1 - 0.0094 14.6 2.6 0.12 10.9 0.0 3.6 4 0 0 4 4 4 1 Adaptin N terminal region DCB PF16213.5 KIY50890.1 - 0.025 14.3 0.2 2.4 7.8 0.0 3.0 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 TAN PF11640.8 KIY50890.1 - 0.038 14.1 3.7 8.2 6.5 0.0 5.5 6 1 0 6 6 6 0 Telomere-length maintenance and DNA damage repair V-ATPase_H_C PF11698.8 KIY50890.1 - 0.047 13.8 0.1 11 6.1 0.0 4.4 5 0 0 5 5 5 0 V-ATPase subunit H Arm PF00514.23 KIY50890.1 - 0.071 13.2 3.5 21 5.3 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cas_Csn2 PF09711.10 KIY50890.1 - 0.13 11.9 0.2 14 5.3 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csn2) HEAT_EZ PF13513.6 KIY50890.1 - 0.24 11.9 19.2 0.32 11.6 0.1 6.9 9 0 0 9 9 7 0 HEAT-like repeat ANAPC5 PF12862.7 KIY50891.1 - 0.00078 19.5 3.0 0.011 15.8 0.2 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 NOC3p PF07540.11 KIY50892.1 - 9.4e-31 106.1 0.0 3.1e-30 104.5 0.0 2.0 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KIY50892.1 - 3e-19 69.7 0.1 3e-18 66.4 0.0 2.5 2 1 1 3 3 3 1 CBF/Mak21 family DUF3246 PF11596.8 KIY50892.1 - 0.022 14.2 0.1 0.022 14.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) BCL_N PF04714.13 KIY50892.1 - 0.49 10.5 3.4 2.6 8.2 0.1 2.8 2 0 0 2 2 2 0 BCL7, N-terminal conserver region DUF4337 PF14235.6 KIY50892.1 - 3.7 7.6 10.4 0.43 10.7 5.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) TEA PF01285.18 KIY50893.1 - 0.00048 20.1 0.1 0.00093 19.2 0.1 1.4 1 0 0 1 1 1 1 TEA/ATTS domain Dicty_REP PF05086.12 KIY50893.1 - 0.097 10.6 1.2 0.14 10.2 1.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MSC PF09402.10 KIY50896.1 - 1.9e-82 277.5 0.1 2.6e-82 277.0 0.1 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KIY50896.1 - 0.0007 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Mis12 PF05859.12 KIY50897.1 - 8.4e-34 116.5 0.0 1.2e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Mis12 protein Herpes_UL56 PF04534.12 KIY50897.1 - 0.0023 17.5 0.2 0.0033 16.9 0.2 1.2 1 0 0 1 1 1 1 Herpesvirus UL56 protein Lzipper-MIP1 PF14389.6 KIY50897.1 - 0.056 13.7 0.7 0.11 12.9 0.7 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 SMC_ScpB PF04079.16 KIY50897.1 - 0.094 12.3 1.0 0.27 10.8 1.0 1.6 1 1 0 1 1 1 0 Segregation and condensation complex subunit ScpB Pyr_redox_2 PF07992.14 KIY50900.1 - 1.3e-10 41.0 0.1 2e-07 30.5 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY50900.1 - 0.0017 18.3 0.2 0.95 9.4 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KIY50900.1 - 0.0056 16.3 0.9 1.1 8.7 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Malic_M PF03949.15 KIY50900.1 - 0.15 11.3 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain OTU PF02338.19 KIY50901.1 - 6.4e-22 78.4 0.0 5.1e-21 75.5 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KIY50901.1 - 1.2e-06 28.2 0.0 0.004 16.6 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain DUF1878 PF08963.10 KIY50901.1 - 0.021 15.3 0.0 0.038 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) Adaptin_N PF01602.20 KIY50902.1 - 2.9e-123 412.2 3.2 3.7e-123 411.9 3.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIY50902.1 - 1.2e-55 188.0 1.6 2.9e-52 177.0 0.1 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY50902.1 - 8.6e-15 54.9 4.4 1.2e-05 25.5 0.2 5.2 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.22 KIY50902.1 - 2e-09 36.9 3.2 0.028 14.6 0.1 5.9 6 0 0 6 6 6 3 HEAT repeat CLASP_N PF12348.8 KIY50902.1 - 0.00028 20.5 0.1 0.0053 16.3 0.1 2.6 2 1 0 2 2 2 1 CLASP N terminal Arm PF00514.23 KIY50902.1 - 0.0057 16.7 0.7 0.7 10.0 0.0 3.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIY50902.1 - 0.068 13.7 4.0 38 4.9 0.1 5.9 8 0 0 8 8 8 0 HEAT-like repeat DUF5578 PF17741.1 KIY50902.1 - 0.24 10.8 2.1 17 4.7 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5578) DUF4477 PF14780.6 KIY50903.1 - 8.1e-11 41.9 0.1 1.1e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Peptidase_M49 PF03571.15 KIY50904.1 - 6.6e-218 724.6 0.0 3.5e-209 695.7 0.0 2.0 2 0 0 2 2 2 2 Peptidase family M49 Pirin PF02678.16 KIY50905.1 - 2.4e-27 95.0 0.3 5.6e-27 93.8 0.3 1.7 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KIY50905.1 - 3.6e-25 88.3 0.0 9.4e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain M20_dimer PF07687.14 KIY50906.1 - 0.14 12.1 0.1 2.8 7.9 0.1 2.3 1 1 0 1 1 1 0 Peptidase dimerisation domain Glucan_synthase PF02364.15 KIY50907.1 - 0 1320.8 0.0 0 1320.4 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KIY50907.1 - 2.9e-42 144.1 0.1 1e-41 142.3 0.1 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RAI16-like PF10257.9 KIY50908.1 - 3.4e-68 230.2 1.0 3.8e-68 230.0 0.1 1.5 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein TerB_C PF15615.6 KIY50908.1 - 0.8 10.0 5.3 13 6.0 0.3 3.2 3 0 0 3 3 3 0 TerB-C domain DnaJ PF00226.31 KIY50909.1 - 6.2e-22 77.5 0.5 6.2e-22 77.5 0.5 2.5 3 0 0 3 3 3 1 DnaJ domain Ribosomal_S21e PF01249.18 KIY50910.1 - 3.2e-40 136.1 0.1 3.5e-40 136.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Fungal_trans PF04082.18 KIY50912.1 - 3.2e-13 49.3 1.3 6e-13 48.4 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY50912.1 - 4.5e-05 23.5 11.6 7.5e-05 22.8 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1005 PF06219.12 KIY50912.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) Trimer_CC PF08954.11 KIY50912.1 - 0.24 11.0 3.7 4.9 6.8 0.6 2.8 3 0 0 3 3 3 0 Trimerisation motif RabGAP-TBC PF00566.18 KIY50913.1 - 8.4e-27 94.2 0.0 4.6e-25 88.5 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain FAD_binding_2 PF00890.24 KIY50914.1 - 5.2e-126 421.1 2.7 6.3e-126 420.8 2.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIY50914.1 - 1.6e-43 147.7 0.2 2.4e-43 147.2 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KIY50914.1 - 1.7e-05 24.2 0.4 0.0009 18.6 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY50914.1 - 3.8e-05 22.9 1.5 0.01 14.9 2.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KIY50914.1 - 4e-05 23.0 0.1 0.03 13.6 0.0 2.7 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.19 KIY50914.1 - 0.003 16.9 0.2 0.0057 15.9 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIY50914.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KIY50914.1 - 0.052 13.1 2.0 0.15 11.6 2.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY50914.1 - 0.07 11.8 2.3 0.74 8.5 1.0 2.9 4 0 0 4 4 4 0 HI0933-like protein G-patch PF01585.23 KIY50915.1 - 1.4e-07 31.3 1.0 4.3e-07 29.7 1.0 1.9 1 0 0 1 1 1 1 G-patch domain Pkinase PF00069.25 KIY50916.1 - 1.9e-42 145.4 0.0 2.4e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY50916.1 - 5.9e-25 88.0 0.0 7.8e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY50916.1 - 0.0053 16.7 0.4 0.022 14.7 0.1 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIY50916.1 - 0.01 15.5 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KIY50916.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KIY50916.1 - 0.16 11.2 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DEAD PF00270.29 KIY50917.1 - 2.8e-47 160.8 0.0 5.9e-46 156.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY50917.1 - 1.3e-28 99.6 0.0 5.7e-28 97.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY50917.1 - 0.00036 20.6 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 KIY50917.1 - 0.041 13.6 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) HEM4 PF02602.15 KIY50917.1 - 0.1 11.9 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD TraA PF05513.11 KIY50917.1 - 0.12 12.7 0.2 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 TraA MARVEL PF01284.23 KIY50918.1 - 0.019 15.0 13.0 0.095 12.7 11.3 2.2 1 1 1 2 2 2 0 Membrane-associating domain LETM1 PF07766.13 KIY50919.1 - 3.9e-101 337.9 0.2 3.9e-101 337.9 0.2 2.0 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 KIY50919.1 - 0.0013 19.1 0.5 0.024 15.1 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 KIY50919.1 - 0.0044 16.8 0.2 0.027 14.3 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KIY50919.1 - 0.009 15.5 1.0 0.21 11.2 0.0 3.4 3 0 0 3 3 3 1 EF hand SAP PF02037.27 KIY50919.1 - 0.071 12.9 0.2 0.84 9.5 0.0 3.0 3 1 0 3 3 3 0 SAP domain DUF5106 PF17127.4 KIY50919.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) 2OG-FeII_Oxy_2 PF13532.6 KIY50920.1 - 9.8e-35 120.5 0.0 6.3e-33 114.6 0.0 2.1 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily USP7_ICP0_bdg PF12436.8 KIY50921.1 - 3.3e-86 288.5 0.2 5.3e-84 281.3 0.0 3.1 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KIY50921.1 - 8e-67 224.9 1.4 4.3e-63 212.7 0.1 3.0 2 1 1 3 3 3 3 Ubiquitin-specific protease C-terminal UCH PF00443.29 KIY50921.1 - 1.2e-48 165.8 0.0 1.8e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY50921.1 - 2.6e-21 76.5 0.0 7.2e-21 75.1 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KIY50921.1 - 4.6e-07 30.0 0.0 2.3e-06 27.7 0.0 2.2 1 0 0 1 1 1 1 MATH domain ubiquitin PF00240.23 KIY50921.1 - 0.1 12.4 2.8 2.2 8.1 0.0 4.0 5 0 0 5 5 5 0 Ubiquitin family HTH_36 PF13730.6 KIY50921.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sec66 PF09802.9 KIY50922.1 - 3.8e-52 176.5 0.0 4.3e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 PepSY_TM PF03929.16 KIY50922.1 - 0.053 13.2 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region RhoGEF PF00621.20 KIY50923.1 - 1.6e-19 70.9 0.1 6.8e-15 55.8 0.1 2.2 2 0 0 2 2 2 2 RhoGEF domain Methyltransf_16 PF10294.9 KIY50924.1 - 3.4e-15 56.2 0.0 5e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIY50924.1 - 0.0016 18.3 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIY50924.1 - 0.099 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4112 PF13430.6 KIY50925.1 - 3.4e-34 117.3 0.3 4.4e-34 116.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DNA_primase_lrg PF04104.14 KIY50927.1 - 5e-78 262.2 0.0 7.8e-78 261.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit HSP70 PF00012.20 KIY50928.1 - 2.5e-263 874.7 4.5 2.9e-263 874.5 4.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY50928.1 - 9.4e-16 57.5 0.1 8.4e-15 54.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KIY50928.1 - 0.00076 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KIY50928.1 - 0.05 12.9 0.2 0.14 11.4 0.3 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 KIY50928.1 - 0.076 12.2 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 StbA protein B56 PF01603.20 KIY50929.1 - 2.7e-193 642.6 6.8 3.2e-193 642.4 6.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SHR3_chaperone PF08229.11 KIY50931.1 - 6e-35 119.9 2.0 7.1e-35 119.7 2.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 RsfS PF02410.15 KIY50932.1 - 9.6e-05 22.8 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Citrate_synt PF00285.21 KIY50933.1 - 2.3e-96 323.0 0.0 2.7e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Asn_synthase PF00733.21 KIY50934.1 - 6e-97 325.5 0.0 1e-57 196.4 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KIY50934.1 - 2.8e-32 111.2 0.0 4.6e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KIY50934.1 - 1.3e-27 96.6 0.0 2.4e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KIY50934.1 - 0.0021 17.6 0.0 0.0069 15.9 0.0 1.8 2 0 0 2 2 2 1 Aluminium induced protein QueC PF06508.13 KIY50934.1 - 0.028 13.9 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KIY50934.1 - 0.033 13.3 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Syntaxin PF00804.25 KIY50935.1 - 1.6e-23 83.4 6.0 1.6e-23 83.4 6.0 1.6 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 KIY50935.1 - 1.9e-08 34.6 3.6 1.9e-08 34.6 3.6 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KIY50935.1 - 3.6e-06 26.9 1.1 3.6e-06 26.9 1.1 3.2 3 1 0 3 3 3 1 SNARE domain SKA1 PF07160.12 KIY50935.1 - 0.00037 20.4 0.6 0.00037 20.4 0.6 2.2 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 1 MCU PF04678.13 KIY50935.1 - 0.011 15.9 0.6 0.011 15.9 0.6 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Lig_C PF18330.1 KIY50935.1 - 0.02 14.9 1.5 0.035 14.1 1.0 1.7 1 1 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF948 PF06103.11 KIY50935.1 - 0.02 15.1 8.5 0.06 13.6 1.1 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2207 PF09972.9 KIY50935.1 - 0.024 13.4 0.2 0.042 12.6 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3611 PF12263.8 KIY50935.1 - 0.028 14.3 0.3 0.044 13.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) BatA PF07584.11 KIY50935.1 - 0.057 13.8 1.5 0.062 13.7 0.2 1.8 2 0 0 2 2 1 0 Aerotolerance regulator N-terminal DotU PF09850.9 KIY50935.1 - 0.11 12.2 2.5 0.16 11.6 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system protein DotU ATP-grasp_5 PF13549.6 KIY50935.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.1 3 0 0 3 3 3 0 ATP-grasp domain ISG65-75 PF11727.8 KIY50935.1 - 0.17 11.1 13.2 0.79 8.9 2.3 2.9 2 1 1 3 3 3 0 Invariant surface glycoprotein NPV_P10 PF05531.12 KIY50935.1 - 0.63 10.6 6.9 8.7 6.9 0.2 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KIY50935.1 - 0.63 10.5 3.3 14 6.2 1.0 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KIY50935.1 - 0.88 9.9 7.5 0.32 11.3 0.7 3.1 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Synaptobrevin PF00957.21 KIY50935.1 - 1.1 9.2 6.7 1 9.2 2.0 3.2 2 2 1 3 3 3 0 Synaptobrevin PAH PF02671.21 KIY50935.1 - 5 7.4 4.8 18 5.5 4.8 2.1 1 1 0 1 1 1 0 Paired amphipathic helix repeat EF_assoc_1 PF08355.12 KIY50936.1 - 0.002 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 KIY50936.1 - 0.0024 17.8 0.1 0.0036 17.3 0.1 1.2 1 0 0 1 1 1 1 EF hand associated EF-hand_7 PF13499.6 KIY50936.1 - 0.0031 17.9 0.0 0.0048 17.3 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair AAA PF00004.29 KIY50937.1 - 2.1e-34 118.8 0.0 4.1e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY50937.1 - 1.3e-10 40.8 0.0 4.1e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIY50937.1 - 4.6e-06 27.1 1.5 0.0019 18.6 0.0 4.4 5 1 0 5 5 5 1 AAA ATPase domain AAA_22 PF13401.6 KIY50937.1 - 0.00097 19.4 0.4 0.033 14.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KIY50937.1 - 0.0027 17.7 0.1 0.019 14.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KIY50937.1 - 0.0034 17.6 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY50937.1 - 0.0039 17.7 0.1 0.1 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIY50937.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KIY50937.1 - 0.0057 16.7 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KIY50937.1 - 0.0066 16.7 0.0 0.079 13.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_6 PF12774.7 KIY50937.1 - 0.013 14.5 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_2 PF07724.14 KIY50937.1 - 0.018 15.2 0.0 0.052 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KIY50937.1 - 0.03 14.1 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 KIY50937.1 - 0.063 13.1 0.3 0.14 11.9 0.0 1.9 2 1 0 2 2 1 0 AAA domain DUF815 PF05673.13 KIY50937.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KIY50937.1 - 0.23 11.3 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain TIP49 PF06068.13 KIY50937.1 - 0.26 10.5 0.0 0.44 9.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain SMC_Nse1 PF07574.13 KIY50938.1 - 1.5e-25 90.3 0.1 8.2e-25 87.8 0.1 1.8 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex CDP-OH_P_transf PF01066.21 KIY50939.1 - 1.3e-12 48.3 2.1 1.4e-11 45.0 0.6 2.3 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CDP-OH_P_transf PF01066.21 KIY50940.1 - 9.1e-13 48.8 0.3 9.1e-13 48.8 0.3 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase p450 PF00067.22 KIY50941.1 - 4.8e-60 203.6 0.0 1.2e-59 202.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 PRKCSH PF07915.13 KIY50942.1 - 8.5e-15 55.5 0.3 1.5e-14 54.7 0.3 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KIY50942.1 - 0.00055 19.6 0.1 0.0038 16.9 0.1 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein AT_hook PF02178.19 KIY50943.1 - 3.3e-07 29.4 47.6 0.028 14.3 3.9 4.5 4 0 0 4 4 4 4 AT hook motif RBR PF17208.3 KIY50943.1 - 0.0082 16.8 5.3 0.0082 16.8 5.3 3.3 1 1 2 3 3 3 1 RNA binding Region FAD_binding_3 PF01494.19 KIY50944.1 - 2.7e-16 59.7 0.4 8e-15 54.9 0.4 2.7 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIY50944.1 - 0.00018 20.7 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KIY50944.1 - 0.00027 20.6 0.0 0.0034 17.0 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY50944.1 - 0.0003 21.0 0.0 0.00072 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY50944.1 - 0.00046 19.5 0.0 0.0034 16.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY50944.1 - 0.00057 20.4 0.0 0.0075 16.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIY50944.1 - 0.0044 16.1 0.0 0.044 12.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.14 KIY50944.1 - 0.0092 14.7 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 KIY50944.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KIY50944.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.21 KIY50944.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KIY50944.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lipoprotein_18 PF06804.11 KIY50944.1 - 0.24 10.4 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Aminotran_5 PF00266.19 KIY50945.1 - 5.5e-11 42.0 0.0 7.6e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Abhydrolase_3 PF07859.13 KIY50946.1 - 7.1e-11 42.4 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY50946.1 - 0.0087 15.0 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Sec34 PF04136.15 KIY50947.1 - 1.4e-48 164.5 0.2 3.1e-48 163.4 0.2 1.6 1 0 0 1 1 1 1 Sec34-like family 23S_rRNA_IVP PF05635.11 KIY50947.1 - 0.032 14.5 0.0 0.44 10.9 0.0 2.6 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein KASH_CCD PF14662.6 KIY50947.1 - 0.097 12.5 0.2 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Abhydrolase_1 PF00561.20 KIY50948.1 - 1.7e-43 149.1 0.0 3.4e-43 148.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY50948.1 - 0.00059 20.5 6.6 0.0011 19.7 6.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pmp3 PF01679.17 KIY50949.1 - 2.8e-23 81.8 10.4 3e-23 81.7 10.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RTA1 PF04479.13 KIY50950.1 - 2.7e-38 131.6 9.7 2.7e-38 131.6 9.7 1.6 1 1 1 2 2 2 1 RTA1 like protein MCM_OB PF17207.3 KIY50950.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 MCM OB domain FUN14 PF04930.15 KIY50951.1 - 5e-21 74.9 0.6 6.9e-21 74.5 0.6 1.2 1 0 0 1 1 1 1 FUN14 family TRP PF06011.12 KIY50951.1 - 0.032 13.0 0.6 0.043 12.5 0.6 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Ion_trans PF00520.31 KIY50952.1 - 0.00034 19.9 0.1 0.00046 19.5 0.1 1.1 1 0 0 1 1 1 1 Ion transport protein Methyltr_RsmB-F PF01189.17 KIY50953.1 - 8.1e-77 257.4 0.0 1.2e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KIY50953.1 - 2.7e-09 37.4 0.0 1e-08 35.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 KIY50953.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 KIY50953.1 - 0.0027 17.5 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY50953.1 - 0.0031 17.3 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 KIY50953.1 - 0.04 13.7 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 KIY50953.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 KIY50953.1 - 0.044 14.5 0.0 0.15 12.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Bradykinin PF06753.12 KIY50953.1 - 0.068 12.9 3.1 0.2 11.4 3.1 1.8 1 0 0 1 1 1 0 Bradykinin RTA1 PF04479.13 KIY50954.1 - 5.5e-44 150.3 5.4 8.1e-44 149.7 5.4 1.2 1 0 0 1 1 1 1 RTA1 like protein 2TM PF13239.6 KIY50954.1 - 3 8.2 5.0 1.2 9.5 0.2 2.5 3 0 0 3 3 3 0 2TM domain SUR7 PF06687.12 KIY50955.1 - 1.5e-11 44.4 18.5 2.2e-07 30.7 11.7 2.1 1 1 1 2 2 2 2 SUR7/PalI family Insulin_TMD PF17870.1 KIY50955.1 - 0.41 10.7 0.1 0.41 10.7 0.1 2.7 4 0 0 4 4 4 0 Insulin receptor trans-membrane segment RDD PF06271.12 KIY50955.1 - 9.3 6.4 12.1 11 6.2 1.9 2.9 1 1 0 2 2 2 0 RDD family Dapper PF15268.6 KIY50956.1 - 2.8 6.7 23.2 3.2 6.5 23.2 1.1 1 0 0 1 1 1 0 Dapper Hexapep PF00132.24 KIY50957.1 - 3.6e-13 48.7 9.6 1.1e-05 24.9 1.0 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) W2 PF02020.18 KIY50957.1 - 3.7e-07 30.2 0.0 3.7e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 KIY50957.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KIY50957.1 - 4.6e-06 26.3 11.6 0.42 10.4 8.2 4.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KIY50957.1 - 3.4e-05 24.3 0.0 7.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KIY50957.1 - 6.5e-05 22.0 0.1 0.00012 21.2 0.1 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KIY50957.1 - 0.032 12.4 2.9 0.13 10.4 2.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) zf-AN1 PF01428.16 KIY50960.1 - 1e-08 35.2 7.8 1e-08 35.2 7.8 1.8 1 1 0 1 1 1 1 AN1-like Zinc finger Rubredoxin_2 PF18073.1 KIY50960.1 - 0.033 13.9 0.2 0.033 13.9 0.2 2.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain PACT_coil_coil PF10495.9 KIY50960.1 - 0.083 13.5 0.1 0.11 13.1 0.1 1.2 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein IBR PF01485.21 KIY50960.1 - 0.14 12.4 9.0 0.18 12.1 8.3 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Aminotran_1_2 PF00155.21 KIY50962.1 - 2.7e-86 290.0 0.0 3.1e-86 289.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT PF02985.22 KIY50963.1 - 4.8e-15 54.4 8.0 0.21 12.0 0.0 9.1 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 KIY50963.1 - 3.2e-09 37.1 3.6 0.34 11.3 0.0 6.4 5 2 2 7 7 7 5 HEAT repeats HEAT_EZ PF13513.6 KIY50963.1 - 0.0042 17.5 6.4 5.5 7.6 0.0 6.2 6 1 1 7 7 7 2 HEAT-like repeat Antimicrobial10 PF08105.11 KIY50964.1 - 1.1 9.3 7.6 0.095 12.8 1.5 2.4 2 0 0 2 2 2 0 Metchnikowin family Glyco_hydro_88 PF07470.13 KIY50965.1 - 7.7e-16 58.1 3.4 1.2e-15 57.5 3.4 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 KIY50965.1 - 0.00043 19.9 12.2 0.0013 18.3 11.8 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.13 KIY50965.1 - 0.002 17.6 0.2 0.31 10.5 0.1 2.4 1 1 1 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 KIY50965.1 - 0.0023 16.5 0.6 1.4 7.4 0.1 2.2 1 1 1 2 2 2 2 Beta-L-arabinofuranosidase, GH127 GlcNAc_2-epim PF07221.11 KIY50965.1 - 0.026 13.8 0.6 0.56 9.4 0.0 2.7 2 1 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Syntaxin PF00804.25 KIY50966.1 - 6.9e-34 117.3 13.5 9.6e-34 116.8 13.5 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KIY50966.1 - 5.2e-07 29.6 5.2 2.7e-06 27.3 5.2 2.2 1 1 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KIY50966.1 - 1.1e-06 28.9 13.8 2.4e-06 27.9 10.0 2.2 2 0 0 2 2 2 1 Syntaxin-like protein DUF5383 PF17355.2 KIY50966.1 - 0.012 16.0 1.7 0.018 15.4 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) VitD-bind_III PF09164.10 KIY50966.1 - 0.022 14.7 0.1 0.063 13.3 0.1 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Spectrin PF00435.21 KIY50966.1 - 0.061 13.8 6.5 1.7 9.2 0.1 2.9 3 0 0 3 3 3 0 Spectrin repeat DASH_Dam1 PF08653.10 KIY50966.1 - 0.07 12.9 0.4 0.07 12.9 0.4 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 MLTR_LBD PF17765.1 KIY50966.1 - 0.076 13.1 0.3 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain WXG100 PF06013.12 KIY50966.1 - 0.12 12.7 12.3 1.5 9.1 0.0 3.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG HsbA PF12296.8 KIY50966.1 - 0.16 12.4 5.1 4.3 7.8 0.2 3.0 2 1 1 3 3 3 0 Hydrophobic surface binding protein A Pox_EPC_I2-L1 PF12575.8 KIY50966.1 - 0.17 12.1 1.7 0.49 10.7 0.8 2.1 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF4094 PF13334.6 KIY50966.1 - 0.2 12.1 2.8 3.5 8.1 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) MCPsignal PF00015.21 KIY50966.1 - 0.22 11.3 11.0 0.089 12.6 2.1 2.8 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4231 PF14015.6 KIY50966.1 - 0.26 11.8 2.0 9.4 6.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) RSS_P20 PF11757.8 KIY50966.1 - 1.1 9.8 5.5 26 5.4 1.3 3.1 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Occludin_ELL PF07303.13 KIY50966.1 - 3.5 8.4 9.5 6.2 7.6 0.0 3.1 2 1 1 3 3 3 0 Occludin homology domain Arc_PepC_II PF06847.11 KIY50966.1 - 5.2 7.7 5.8 94 3.6 5.8 2.8 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Sigma_reg_N PF13800.6 KIY50966.1 - 5.6 7.3 8.2 3.4 8.0 5.0 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal PIN_8 PF18476.1 KIY50966.1 - 6.7 6.5 12.7 1.9 8.3 4.8 2.4 1 1 2 3 3 3 0 PIN like domain ABC_tran_CTD PF16326.5 KIY50966.1 - 7.5 6.9 10.2 0.82 10.0 1.5 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF745 PF05335.13 KIY50966.1 - 9.1 6.0 17.5 3.4 7.4 5.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Lyase_1 PF00206.20 KIY50967.1 - 1.5e-98 330.1 0.0 2e-98 329.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KIY50967.1 - 7.7e-23 81.0 0.1 1.8e-22 79.8 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal MFS_1 PF07690.16 KIY50968.1 - 1.4e-17 63.7 59.8 7.2e-17 61.3 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KIY50968.1 - 1.4e-07 31.2 8.1 1.4e-07 31.2 8.1 1.9 2 0 0 2 2 2 1 Nodulin-like CUE PF02845.16 KIY50969.1 - 0.0056 16.4 0.2 0.038 13.7 0.2 2.4 1 1 0 1 1 1 1 CUE domain N36 PF11438.8 KIY50969.1 - 0.15 11.9 2.6 0.52 10.2 2.6 1.9 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) FXMRP1_C_core PF12235.8 KIY50969.1 - 2.2 8.9 10.9 0.29 11.8 5.9 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Rep_fac-A_3 PF08661.11 KIY50970.1 - 4.3e-20 72.0 0.0 4.9e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Myosin_N PF02736.19 KIY50970.1 - 0.11 12.3 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Ist1 PF03398.14 KIY50972.1 - 2.5e-28 99.1 0.0 3.6e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 KIY50972.1 - 1.6e-09 37.7 0.2 1.7e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PIG-H PF10181.9 KIY50973.1 - 1.5e-17 63.2 0.0 2.5e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ALG3 PF05208.13 KIY50974.1 - 2.2e-134 448.4 19.1 2.7e-134 448.1 19.1 1.0 1 0 0 1 1 1 1 ALG3 protein RCC1 PF00415.18 KIY50975.1 - 5.9e-19 68.4 2.0 0.0023 18.5 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KIY50975.1 - 9.3e-15 54.8 0.2 1.8e-06 28.2 0.0 3.1 2 1 1 3 3 3 2 BTB/POZ domain Ank_5 PF13857.6 KIY50975.1 - 7.6e-09 35.7 0.5 3.3e-05 24.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY50975.1 - 3.8e-08 33.8 0.1 1.5e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY50975.1 - 9.1e-08 32.5 2.0 2.9e-06 27.7 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY50975.1 - 3.3e-07 30.1 1.5 0.00094 19.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat RCC1_2 PF13540.6 KIY50975.1 - 6.5e-06 25.8 9.1 1.7e-05 24.5 0.1 5.3 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.30 KIY50975.1 - 4e-05 23.9 1.9 0.012 16.0 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat SURF6 PF04935.12 KIY50976.1 - 1.3e-29 103.4 34.2 1.3e-29 103.4 34.2 2.4 2 0 0 2 2 2 2 Surfeit locus protein 6 RRP14 PF15459.6 KIY50976.1 - 1.1e-15 57.9 4.3 1.1e-15 57.9 4.3 4.3 3 1 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 Metallopep PF12044.8 KIY50977.1 - 6.3e-118 394.1 0.0 8.9e-118 393.6 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 KIY50977.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KIY50977.1 - 0.037 13.0 0.7 0.069 12.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase M66 Reprolysin_3 PF13582.6 KIY50977.1 - 0.048 14.2 0.3 0.12 12.9 0.3 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Glyco_transf_28 PF03033.20 KIY50979.1 - 1.3e-25 90.1 0.0 2.7e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KIY50979.1 - 9.4e-09 34.6 0.0 2.1e-08 33.5 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAM PF02893.20 KIY50979.1 - 9.5e-07 28.7 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 GRAM domain Aminotran_5 PF00266.19 KIY50980.1 - 3.3e-32 111.9 0.0 5.2e-32 111.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V G-alpha PF00503.20 KIY50981.1 - 8.3e-96 321.2 0.0 9.7e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY50981.1 - 2.6e-06 27.0 0.0 7.1e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family TRAPPC10 PF12584.8 KIY50982.1 - 4.8e-29 101.1 0.0 2.4e-28 98.8 0.0 2.1 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 SSTK-IP PF15836.5 KIY50982.1 - 0.019 15.1 0.0 0.059 13.5 0.0 1.9 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Cas3_C PF18395.1 KIY50982.1 - 0.14 12.6 0.4 16 6.0 0.1 2.9 2 0 0 2 2 2 0 Cas3 C-terminal domain DEAD PF00270.29 KIY50983.1 - 4e-51 173.2 0.0 6.6e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY50983.1 - 9.6e-31 106.4 0.0 2.8e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY50983.1 - 3.9e-06 27.0 0.0 7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Trs65 PF12735.7 KIY50984.1 - 4.1e-20 72.4 0.0 3e-11 43.3 0.1 3.3 3 0 0 3 3 3 3 TRAPP trafficking subunit Trs65 Glycos_transf_1 PF00534.20 KIY50985.1 - 5.6e-18 65.1 0.0 1.6e-17 63.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIY50985.1 - 1.8e-10 41.3 0.0 3.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIY50985.1 - 1.1e-05 25.7 0.0 2.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIY50985.1 - 0.09 12.8 0.0 1.4 8.9 0.0 2.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 TF_Zn_Ribbon PF08271.12 KIY50986.1 - 0.21 11.2 1.7 0.61 9.7 1.7 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RRN7 PF11781.8 KIY50986.1 - 0.5 10.1 2.1 5.1 6.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Methyltransf_11 PF08241.12 KIY50988.1 - 1.9e-09 38.1 0.0 4.3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY50988.1 - 4.4e-09 36.9 0.0 1.8e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY50988.1 - 6.2e-06 26.1 0.0 9.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY50988.1 - 0.00031 21.4 0.0 0.00059 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIY50988.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 KIY50988.1 - 0.004 17.0 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TP_methylase PF00590.20 KIY50989.1 - 3e-43 148.2 1.6 3e-43 148.2 1.6 1.8 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KIY50989.1 - 3e-13 50.1 0.2 3.1e-12 46.8 0.2 2.5 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KIY50989.1 - 8.4e-08 31.7 0.5 2.6e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KIY50989.1 - 2.5e-05 23.6 0.1 5.4e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DHR10 PF18595.1 KIY50990.1 - 0.00018 21.6 14.5 0.00018 21.6 14.5 4.3 3 1 2 5 5 5 1 Designed helical repeat protein 10 domain TPR_MLP1_2 PF07926.12 KIY50990.1 - 0.07 13.2 46.5 0.27 11.3 16.9 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein JIP_LZII PF16471.5 KIY50990.1 - 0.099 12.8 0.2 0.099 12.8 0.2 5.0 5 0 0 5 5 5 0 JNK-interacting protein leucine zipper II DUF1727 PF08353.10 KIY50990.1 - 0.17 11.8 0.5 0.52 10.3 0.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1727) ZnuA PF01297.17 KIY50990.1 - 1.7 8.0 12.1 0.43 10.0 7.4 2.3 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic CENP-F_leu_zip PF10473.9 KIY50990.1 - 2.3 8.2 33.4 0.43 10.6 11.2 3.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 KIY50990.1 - 3.4 6.8 23.1 0.29 10.3 6.3 2.5 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 KIY50990.1 - 3.7 7.6 17.7 6.3 6.9 1.6 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) MAD PF05557.13 KIY50990.1 - 5.1 5.3 40.1 15 3.8 39.3 2.0 1 1 0 1 1 1 0 Mitotic checkpoint protein DPM3 PF08285.11 KIY50991.1 - 1.9e-31 108.1 0.1 2.1e-31 108.0 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) NAC PF01849.18 KIY50992.1 - 3.8e-20 71.6 0.0 7.4e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 NAC domain DUF4719 PF15843.5 KIY50992.1 - 0.068 13.3 0.2 0.095 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) UBA_4 PF14555.6 KIY50992.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain HSP90 PF00183.18 KIY50993.1 - 2.2e-232 772.5 25.4 2.8e-232 772.2 25.4 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KIY50993.1 - 2.6e-13 50.4 0.1 5.1e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIY50993.1 - 5.2e-09 36.1 0.1 5.2e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 KIY50993.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN DUF1943 PF09172.11 KIY50993.1 - 0.35 10.1 4.5 0.64 9.2 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Casc1 PF12366.8 KIY50993.1 - 0.76 9.3 12.1 1.5 8.3 7.7 2.5 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 ETRAMP PF09716.10 KIY50993.1 - 3 8.0 5.9 13 5.9 5.9 2.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2052 PF09747.9 KIY50993.1 - 6.2 6.9 15.4 2.9 8.0 11.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) 2OG-FeII_Oxy_3 PF13640.6 KIY50994.1 - 1.8e-06 28.7 0.1 3.2e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA PF00004.29 KIY50995.1 - 2e-44 151.2 0.1 7.5e-44 149.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIY50995.1 - 9.1e-10 38.3 0.1 6.3e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KIY50995.1 - 5.1e-08 33.0 0.1 1.7e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY50995.1 - 1.4e-07 31.8 0.0 3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KIY50995.1 - 1.8e-07 31.7 1.6 3.2e-05 24.4 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KIY50995.1 - 2e-06 27.2 0.0 3.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 KIY50995.1 - 3.3e-05 23.6 0.0 8.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 KIY50995.1 - 0.0001 22.9 0.0 0.0023 18.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KIY50995.1 - 0.0002 20.7 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 KIY50995.1 - 0.00033 20.9 0.0 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIY50995.1 - 0.00064 20.0 4.2 0.014 15.6 0.1 2.9 3 1 1 4 4 2 1 AAA domain RuvB_N PF05496.12 KIY50995.1 - 0.00065 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KIY50995.1 - 0.00069 19.6 0.0 0.0029 17.7 0.0 2.0 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 KIY50995.1 - 0.00081 19.4 0.0 0.011 15.8 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KIY50995.1 - 0.00091 19.2 0.1 0.019 14.9 0.0 2.7 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.22 KIY50995.1 - 0.002 18.5 0.0 0.0054 17.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KIY50995.1 - 0.0025 18.0 0.1 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY50995.1 - 0.0027 17.5 0.4 0.0072 16.1 0.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY50995.1 - 0.0037 17.0 0.2 0.017 14.8 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KIY50995.1 - 0.0041 16.6 0.1 0.03 13.8 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KIY50995.1 - 0.0089 15.4 0.1 0.021 14.2 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIY50995.1 - 0.011 15.3 0.4 0.064 12.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KIY50995.1 - 0.012 15.6 0.1 0.092 12.7 0.1 2.2 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 KIY50995.1 - 0.013 14.9 0.0 0.61 9.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 KIY50995.1 - 0.015 15.2 0.0 0.041 13.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIY50995.1 - 0.019 14.7 0.1 0.04 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIY50995.1 - 0.044 13.6 0.2 0.078 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 KIY50995.1 - 0.046 14.1 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KIY50995.1 - 0.065 12.1 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.18 KIY50995.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 KIY50995.1 - 0.12 12.3 0.8 0.78 9.6 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KIY50995.1 - 0.13 12.0 0.4 1.2 8.8 0.0 2.5 3 1 0 3 3 2 0 Sigma-54 interaction domain ATPase PF06745.13 KIY50995.1 - 0.14 11.5 0.6 0.53 9.6 0.0 2.1 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.27 KIY50995.1 - 0.15 12.6 0.1 0.91 10.0 0.0 2.3 3 0 0 3 3 2 0 ABC transporter Parvo_NS1 PF01057.17 KIY50995.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RRM_1 PF00076.22 KIY50996.1 - 1.7e-13 50.2 0.0 4.6e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNRNP27 PF08648.12 KIY50998.1 - 5.9e-29 99.9 1.1 9.7e-29 99.2 1.1 1.3 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins SUI1 PF01253.22 KIY50999.1 - 8.9e-28 96.6 0.3 1.2e-27 96.2 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 PPP4R2 PF09184.11 KIY51001.1 - 3.8e-19 69.4 0.2 6.1e-19 68.7 0.2 1.4 1 1 0 1 1 1 1 PPP4R2 PAP2 PF01569.21 KIY51002.1 - 5.3e-32 110.4 3.6 8.6e-32 109.7 3.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily DNA_pol_phi PF04931.13 KIY51003.1 - 3.6e-221 736.4 13.3 3.6e-221 736.4 13.3 1.4 2 0 0 2 2 2 1 DNA polymerase phi MutS_V PF00488.21 KIY51004.1 - 4.6e-70 235.5 2.3 6.5e-70 235.0 0.4 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KIY51004.1 - 1.6e-33 116.5 0.3 4.8e-33 115.0 0.3 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KIY51004.1 - 5.9e-27 94.1 0.1 1.1e-26 93.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KIY51004.1 - 6.3e-06 26.5 0.2 1.9e-05 24.9 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KIY51004.1 - 0.0012 19.2 0.2 0.01 16.1 0.2 2.6 1 1 0 1 1 1 1 MutS domain II ATP12 PF07542.11 KIY51005.1 - 4.9e-42 143.1 3.0 5.9e-42 142.8 0.5 2.0 2 0 0 2 2 2 1 ATP12 chaperone protein Nt_Gln_amidase PF09764.9 KIY51006.1 - 2.1e-50 170.9 0.1 2.6e-50 170.6 0.1 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase BTB PF00651.31 KIY51007.1 - 0.006 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain UQ_con PF00179.26 KIY51010.1 - 2e-42 144.2 0.0 2.2e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY51010.1 - 0.0016 18.7 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KIY51010.1 - 0.002 17.8 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KIY51010.1 - 0.0071 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Arylsulfotran_2 PF14269.6 KIY51011.1 - 2.5e-46 158.4 0.0 3.1e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY51011.1 - 1.7e-18 66.7 0.0 4.5e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) RF-1 PF00472.20 KIY51012.1 - 6.5e-23 80.9 2.5 6.5e-23 80.9 2.5 1.9 2 1 1 3 3 3 1 RF-1 domain Linker_histone PF00538.19 KIY51013.1 - 2e-23 82.5 0.0 2e-23 82.5 0.0 2.5 3 0 0 3 3 3 1 linker histone H1 and H5 family Cbl_N3 PF02762.14 KIY51013.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain CAP_N PF01213.19 KIY51014.1 - 1.8e-83 280.7 28.6 1.7e-81 274.1 28.6 3.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KIY51014.1 - 2.8e-59 199.2 4.6 4.1e-59 198.7 4.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KIY51014.1 - 0.0018 18.0 1.9 0.003 17.3 1.9 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C PhoD PF09423.10 KIY51015.1 - 0.19 10.7 0.1 1.3 7.9 0.0 2.1 3 0 0 3 3 3 0 PhoD-like phosphatase SPRY PF00622.28 KIY51016.1 - 3.9e-10 39.9 0.0 5.5e-06 26.5 0.0 3.4 3 0 0 3 3 3 3 SPRY domain ISG65-75 PF11727.8 KIY51016.1 - 1.2 8.3 9.3 1.8 7.7 9.3 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3807 PF12720.7 KIY51016.1 - 2.7 8.2 10.7 6.3 7.0 6.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Ribosomal_S8 PF00410.19 KIY51017.1 - 7e-11 42.2 0.0 2e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8 Cpn60_TCP1 PF00118.24 KIY51018.1 - 1.3e-147 492.4 13.0 1.4e-147 492.3 13.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 KIY51018.1 - 0.0016 18.0 0.2 0.0037 16.8 0.0 1.7 2 0 0 2 2 2 1 Telomere recombination tRNA_int_endo PF01974.17 KIY51019.1 - 1.4e-14 53.9 0.0 5.6e-14 52.0 0.0 2.0 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Herpes_capsid PF06112.11 KIY51019.1 - 0.068 13.2 0.3 0.1 12.7 0.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CLTH PF10607.9 KIY51020.1 - 6.8e-20 71.5 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KIY51020.1 - 3.2e-07 30.3 0.1 5.8e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger CdvA PF18822.1 KIY51020.1 - 0.0014 18.4 0.1 0.0027 17.5 0.1 1.4 1 0 0 1 1 1 1 CdvA-like coiled-coil domain zf-RING_2 PF13639.6 KIY51020.1 - 0.0022 18.3 0.1 0.0037 17.5 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIY51020.1 - 0.0023 17.9 0.1 0.0042 17.0 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Rtf2 PF04641.12 KIY51020.1 - 0.003 16.9 0.1 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KIY51020.1 - 0.012 15.5 0.5 0.022 14.5 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 KIY51020.1 - 0.038 13.8 0.2 0.068 13.1 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY51020.1 - 0.19 11.6 0.3 0.38 10.6 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pellino PF04710.14 KIY51020.1 - 0.21 10.2 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Pellino EI24 PF07264.11 KIY51021.1 - 1.4e-34 119.9 17.3 2e-34 119.4 17.3 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.6 KIY51021.1 - 0.0076 16.5 0.4 0.025 14.9 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Rhodanese PF00581.20 KIY51022.1 - 9.7e-12 45.4 0.0 2.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Lipase_GDSL_2 PF13472.6 KIY51023.1 - 4.7e-30 105.3 0.0 6.6e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY51023.1 - 3.9e-18 66.2 0.0 6.3e-18 65.5 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TPR_1 PF00515.28 KIY51024.1 - 9.5e-23 79.0 4.7 4.4e-08 32.6 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIY51024.1 - 7.2e-22 75.7 9.1 3.1e-05 23.8 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY51024.1 - 9e-19 67.5 10.0 1.7e-12 47.3 0.2 4.8 3 1 2 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KIY51024.1 - 1.8e-12 46.7 0.1 0.061 13.0 0.0 6.2 5 1 1 6 6 6 3 TPR repeat TPR_8 PF13181.6 KIY51024.1 - 7.7e-12 44.4 0.5 0.017 15.3 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY51024.1 - 2.9e-10 39.8 7.8 0.067 13.6 0.1 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY51024.1 - 9.7e-08 32.4 26.0 0.0021 18.5 0.0 7.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY51024.1 - 4.3e-07 30.2 30.3 0.22 12.5 0.7 8.7 7 2 4 11 11 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIY51024.1 - 4e-06 27.4 30.8 5.7e-05 23.7 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY51024.1 - 5e-06 26.7 13.5 0.011 16.1 0.1 6.7 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY51024.1 - 9.8e-06 25.3 6.6 0.38 10.9 0.0 6.6 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY51024.1 - 0.0033 18.0 19.8 0.82 10.4 0.0 8.5 9 1 0 10 10 8 1 Tetratricopeptide repeat DUF908 PF06012.12 KIY51024.1 - 0.62 9.4 9.1 1.1 8.6 9.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TPR_9 PF13371.6 KIY51024.1 - 6.8 6.9 17.3 0.4 10.9 0.7 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat SRP-alpha_N PF04086.13 KIY51024.1 - 7.8 6.3 11.8 11 5.8 11.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pre-PUA PF17832.1 KIY51026.1 - 9.4e-25 87.1 0.0 1.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KIY51026.1 - 5e-15 55.2 0.1 9.1e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KIY51026.1 - 0.0057 16.9 0.1 0.016 15.5 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1947) CRM1_C PF08767.11 KIY51027.1 - 3.4e-126 420.8 1.4 3.4e-126 420.8 1.4 3.0 2 1 1 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KIY51027.1 - 8.3e-39 133.0 12.9 9.1e-39 132.9 8.1 3.5 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KIY51027.1 - 1.1e-33 114.6 4.1 3.6e-33 113.0 4.1 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KIY51027.1 - 1.5e-29 101.9 1.1 1.5e-29 101.9 1.1 3.0 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KIY51027.1 - 1.5e-18 66.0 2.4 1.5e-18 66.0 2.4 2.5 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KIY51027.1 - 1.1e-11 44.5 0.0 4.3e-11 42.6 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KIY51027.1 - 0.023 14.6 1.3 0.23 11.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KIY51027.1 - 0.14 12.8 1.0 7.1 7.3 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region GET2 PF08690.10 KIY51028.1 - 0.12 12.0 7.0 0.19 11.4 7.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 ADH_zinc_N_2 PF13602.6 KIY51029.1 - 1.2e-22 81.3 0.0 4.7e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIY51029.1 - 8.8e-16 58.1 0.5 2.4e-15 56.7 0.0 2.0 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY51029.1 - 0.021 14.7 0.0 3.5 7.5 0.0 3.3 3 1 1 4 4 4 0 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KIY51029.1 - 0.038 13.3 2.3 0.058 12.7 2.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cas_VVA1548 PF09652.10 KIY51029.1 - 0.15 12.3 0.0 1.9 8.7 0.0 2.6 2 1 1 3 3 3 0 Putative CRISPR-associated protein (Cas_VVA1548) R3H PF01424.22 KIY51030.1 - 8.3e-09 35.3 0.0 2.1e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KIY51030.1 - 5.4e-06 26.2 0.2 5.4e-06 26.2 0.2 2.6 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KIY51030.1 - 0.00022 21.2 0.1 0.0007 19.6 0.1 1.9 1 0 0 1 1 1 1 G-patch domain 2Fe-2S_thioredx PF01257.19 KIY51031.1 - 1.4e-58 196.9 0.0 1.7e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Chorismate_bind PF00425.18 KIY51032.1 - 1.1e-92 310.2 0.0 1.8e-92 309.6 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KIY51032.1 - 1.3e-27 96.7 0.0 5.3e-27 94.8 0.0 2.1 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.20 KIY51033.1 - 1.7e-58 197.4 0.3 1.4e-33 115.9 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 HSP70 PF00012.20 KIY51034.1 - 9e-237 787.0 7.3 1.1e-236 786.8 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY51034.1 - 6.7e-17 61.3 0.6 6.9e-16 58.0 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 KIY51034.1 - 0.0016 18.0 1.0 1.9 7.9 0.0 3.0 3 1 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 KIY51034.1 - 0.011 14.7 0.2 0.17 10.8 0.1 2.4 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 KIY51034.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Zincin_2 PF10103.9 KIY51034.1 - 0.071 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase FtsA PF14450.6 KIY51034.1 - 3.7 8.0 6.4 36 4.8 0.1 3.4 3 2 0 3 3 3 0 Cell division protein FtsA Metallophos_2 PF12850.7 KIY51035.1 - 1.7e-15 57.6 0.3 2.4e-15 57.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KIY51035.1 - 7.1e-05 23.4 0.8 0.26 11.8 0.2 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase BAG PF02179.16 KIY51037.1 - 2e-09 37.7 0.9 4.3e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 BAG domain K1377 PF15352.6 KIY51037.1 - 2.9 6.1 8.4 0.77 7.9 2.6 2.0 2 0 0 2 2 2 0 Susceptibility to monomelic amyotrophy Telomere_reg-2 PF10193.9 KIY51038.1 - 6e-31 107.1 0.0 1.3e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein 3-alpha PF03475.14 KIY51038.1 - 0.69 9.8 3.1 0.62 10.0 1.0 2.1 2 0 0 2 2 2 0 3-alpha domain RPA_interact_N PF14766.6 KIY51039.1 - 4.4 7.0 10.6 1.5 8.5 6.1 2.3 2 0 0 2 2 2 0 Replication protein A interacting N-terminal CAF1A PF12253.8 KIY51040.1 - 6.7e-20 71.0 3.3 6.7e-20 71.0 3.3 2.4 2 1 1 3 3 3 1 Chromatin assembly factor 1 subunit A Mcm10 PF09332.11 KIY51040.1 - 0.009 15.5 5.5 0.018 14.5 5.5 1.4 1 0 0 1 1 1 1 Mcm10 replication factor CEP76-C2 PF15627.6 KIY51040.1 - 0.046 13.3 0.8 0.087 12.4 0.8 1.4 1 0 0 1 1 1 0 CEP76 C2 domain Spc24 PF08286.11 KIY51041.1 - 1.1e-11 44.9 0.1 8.7e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 MCC-bdg_PDZ PF10506.9 KIY51041.1 - 0.15 12.1 1.5 1.3 9.1 0.4 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Glyco_hydro_71 PF03659.14 KIY51042.1 - 1.6e-118 395.8 3.2 1.9e-118 395.6 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 AAA PF00004.29 KIY51043.1 - 6.2e-15 55.8 0.0 2e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KIY51043.1 - 2.1e-11 43.9 0.0 2.1e-09 37.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KIY51043.1 - 1.4e-10 41.4 0.1 5.4e-10 39.6 0.1 2.0 1 1 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 KIY51043.1 - 5e-07 29.8 0.0 1.1e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KIY51043.1 - 4.2e-06 27.0 0.0 9.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 KIY51043.1 - 2.6e-05 24.5 0.0 0.00018 21.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KIY51043.1 - 3e-05 24.5 0.0 0.00012 22.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 KIY51043.1 - 4.8e-05 23.3 0.0 8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIY51043.1 - 0.00042 20.3 0.0 0.0016 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIY51043.1 - 0.00043 20.1 0.1 0.0015 18.3 0.0 2.0 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KIY51043.1 - 0.00054 19.7 0.0 0.002 17.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY51043.1 - 0.0019 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIY51043.1 - 0.0044 16.6 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KIY51043.1 - 0.0067 15.8 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KIY51043.1 - 0.0091 16.3 0.0 0.057 13.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KIY51043.1 - 0.012 15.6 0.0 0.062 13.3 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KIY51043.1 - 0.043 13.1 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KIY51043.1 - 0.052 14.1 0.0 0.073 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIY51043.1 - 0.055 13.7 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KIY51043.1 - 0.063 13.0 0.1 0.72 9.6 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase DUF815 PF05673.13 KIY51043.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 KIY51043.1 - 0.11 11.9 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_2 PF07724.14 KIY51043.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KIY51043.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIY51043.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HSF_DNA-bind PF00447.17 KIY51044.1 - 1.2e-31 109.2 4.6 2.3e-31 108.3 4.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KIY51044.1 - 1.2e-23 83.4 0.0 4.9e-23 81.4 0.0 2.1 3 0 0 3 3 3 1 Response regulator receiver domain PMSR PF01625.21 KIY51045.1 - 9.3e-61 204.5 0.1 1.1e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase AMP-binding PF00501.28 KIY51047.1 - 1.9e-15 56.4 0.0 2.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Linker_histone PF00538.19 KIY51048.1 - 2.6e-24 85.4 0.9 6.8e-24 84.0 0.0 2.2 2 1 0 2 2 2 1 linker histone H1 and H5 family FACT-Spt16_Nlob PF14826.6 KIY51048.1 - 0.19 11.5 2.7 0.38 10.5 2.7 1.5 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain Linker_histone PF00538.19 KIY51049.1 - 2.8e-21 75.6 0.0 2.8e-21 75.6 0.0 3.5 3 2 1 4 4 4 1 linker histone H1 and H5 family HC2 PF07382.11 KIY51049.1 - 0.89 9.6 79.6 0.81 9.7 59.5 2.3 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 DUF3188 PF11384.8 KIY51052.1 - 5.9 6.7 8.2 2.6 7.8 1.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) FdhD-NarQ PF02634.15 KIY51053.1 - 0.023 14.4 0.7 0.032 13.9 0.7 1.2 1 0 0 1 1 1 0 FdhD/NarQ family DUF1771 PF08590.10 KIY51055.1 - 9.7e-22 77.1 3.8 9.7e-22 77.1 3.8 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.21 KIY51055.1 - 2.7e-11 43.7 0.9 7.3e-11 42.3 0.9 1.8 1 0 0 1 1 1 1 Smr domain RCR PF12273.8 KIY51055.1 - 0.0096 16.6 2.8 0.016 15.9 2.8 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DIT1_PvcA PF05141.12 KIY51055.1 - 0.52 9.7 2.5 0.71 9.3 2.5 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Spt20 PF12090.8 KIY51055.1 - 4 7.0 11.4 5.7 6.5 11.4 1.2 1 0 0 1 1 1 0 Spt20 family Acetyltransf_1 PF00583.25 KIY51056.1 - 7.4e-15 55.2 0.0 9.9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY51056.1 - 2e-09 37.4 0.0 2.5e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY51056.1 - 4.4e-09 36.2 0.0 6.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KIY51056.1 - 2.1e-08 34.4 0.0 3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY51056.1 - 4.3e-05 23.6 0.0 5.7e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIY51056.1 - 6.4e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIY51056.1 - 0.00025 21.7 0.0 0.00061 20.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIY51056.1 - 0.0095 16.0 0.0 0.016 15.3 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Prim-Pol PF09250.11 KIY51057.1 - 0.06 13.7 0.2 0.43 10.9 0.0 2.4 1 1 1 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal RRM_1 PF00076.22 KIY51058.1 - 1.1e-25 89.2 0.0 1.3e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 KIY51058.1 - 5.5e-21 73.0 0.0 4e-05 23.1 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 KIY51058.1 - 1.4e-05 24.8 0.0 0.058 13.3 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 KIY51058.1 - 0.11 12.0 0.0 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 RNA-recognition motif E1-E2_ATPase PF00122.20 KIY51059.1 - 9.6e-52 175.1 1.1 9.6e-52 175.1 1.1 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIY51059.1 - 1.1e-43 149.0 9.7 1.1e-43 149.0 9.7 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIY51059.1 - 1.3e-21 77.9 0.2 3.8e-17 63.3 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIY51059.1 - 1.8e-19 69.2 0.2 4e-18 64.8 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KIY51059.1 - 1.2e-18 66.9 0.1 2.6e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIY51059.1 - 1.8e-06 27.9 2.9 4e-06 26.8 1.2 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY51059.1 - 1.1e-05 25.9 0.0 2.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RCC1 PF00415.18 KIY51062.1 - 7.5e-21 74.5 8.4 2.6e-07 31.1 0.0 6.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY51062.1 - 1.1e-07 31.4 19.3 0.0018 18.0 0.2 6.9 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat NHL PF01436.21 KIY51062.1 - 0.17 12.0 1.2 4.2 7.6 0.1 2.8 3 0 0 3 3 3 0 NHL repeat DPBB_1 PF03330.18 KIY51064.1 - 0.00014 22.0 0.0 0.00019 21.6 0.0 1.3 1 1 0 1 1 1 1 Lytic transglycolase MAP65_ASE1 PF03999.12 KIY51065.1 - 3.3 6.3 10.0 5.2 5.6 10.0 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PAP2 PF01569.21 KIY51066.1 - 8.8e-17 61.1 10.0 8.8e-17 61.1 10.0 2.2 2 0 0 2 2 2 1 PAP2 superfamily WAC_Acf1_DNA_bd PF10537.9 KIY51067.1 - 0.091 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF2385 PF09539.10 KIY51068.1 - 0.069 13.7 1.1 0.2 12.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) DNA_repr_REX1B PF14966.6 KIY51070.1 - 0.1 13.3 0.2 1.1 9.9 0.1 2.5 1 1 1 2 2 2 0 DNA repair REX1-B Bestrophin PF01062.21 KIY51072.1 - 1e-33 117.0 0.5 1.1e-15 57.8 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel SHQ1 PF04925.15 KIY51073.1 - 6e-56 188.8 0.1 8.7e-56 188.2 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 KIY51073.1 - 0.0004 20.8 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 KIY51073.1 - 0.0056 17.7 0.0 0.019 16.0 0.0 1.9 2 0 0 2 2 2 1 CS domain Nuc_sug_transp PF04142.15 KIY51074.1 - 3.7e-08 32.9 0.1 3.7e-08 32.9 0.1 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.16 KIY51074.1 - 1.4e-07 31.2 6.7 1.5e-05 24.5 0.4 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KIY51074.1 - 1.2e-05 25.5 3.7 1.2e-05 25.5 3.7 2.9 3 0 0 3 3 3 1 EamA-like transporter family SMP_LBD PF17047.5 KIY51074.1 - 0.016 14.7 0.6 0.037 13.5 0.2 1.7 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain Na_H_Exchanger PF00999.21 KIY51077.1 - 1.6e-07 30.5 3.3 1.4e-05 24.1 0.7 2.0 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 KIY51078.1 - 9.1e-59 199.2 30.6 9.1e-59 199.2 30.6 1.9 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family Ank_5 PF13857.6 KIY51079.1 - 0.007 16.7 0.0 1.3 9.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY51079.1 - 0.09 13.4 0.0 0.45 11.1 0.0 2.2 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Humanin PF15040.6 KIY51079.1 - 3.8 7.0 4.5 2.3 7.8 1.2 2.1 2 0 0 2 2 2 0 Humanin family DNA_pol_D_N PF18018.1 KIY51080.1 - 3.7e-38 130.6 0.0 6.6e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KIY51080.1 - 1.6e-32 112.5 0.0 2.3e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Toxin_5 PF05294.13 KIY51080.1 - 0.26 11.8 0.6 0.58 10.6 0.6 1.6 1 0 0 1 1 1 0 Scorpion short toxin EAP30 PF04157.16 KIY51081.1 - 2.1e-70 236.7 0.0 2.4e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Sds3 PF08598.11 KIY51082.1 - 4.7e-24 85.6 0.2 1.7e-23 83.8 0.0 2.0 2 0 0 2 2 2 1 Sds3-like MAGE PF01454.19 KIY51083.1 - 1.2e-51 175.4 0.0 1.5e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 MAGE family Glyco_hydro_63 PF03200.16 KIY51084.1 - 8.1e-161 536.1 0.0 1.5e-159 531.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KIY51084.1 - 1.2e-73 248.0 0.0 5.8e-73 245.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KIY51084.1 - 5.1e-07 28.9 0.0 7.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 KIY51084.1 - 0.047 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Lactamase_B_2 PF12706.7 KIY51086.1 - 4.8e-08 32.8 0.1 6.4e-06 25.8 0.1 2.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY51086.1 - 4.9e-05 23.4 0.0 8.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 KIY51086.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 tRNase Z endonuclease Ribosomal_L21p PF00829.21 KIY51087.1 - 2.6e-22 79.0 0.1 3.3e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 KIY51087.1 - 0.06 13.4 0.2 0.39 10.8 0.2 2.0 1 1 0 1 1 1 0 UvrA interaction domain CMS1 PF14617.6 KIY51088.1 - 2.8e-65 220.2 0.0 3.3e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KIY51088.1 - 0.042 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase L31 PF09784.9 KIY51089.1 - 1.7e-41 140.7 0.2 1.9e-41 140.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 PRP21_like_P PF12230.8 KIY51090.1 - 1.6e-49 168.8 8.8 1.6e-49 168.8 8.8 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KIY51090.1 - 3.8e-33 113.3 2.4 1.5e-16 60.1 0.1 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 KIY51090.1 - 1.2e-08 34.6 0.0 2.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 KIY51090.1 - 0.00042 19.8 0.2 0.00099 18.7 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Rad60-SLD PF11976.8 KIY51090.1 - 0.085 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KIY51090.1 - 0.11 13.1 3.1 0.15 12.6 0.0 2.6 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain Med19 PF10278.9 KIY51090.1 - 4 7.3 9.7 0.4 10.6 0.9 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 eIF3_N PF09440.10 KIY51090.1 - 6.3 7.2 7.7 0.63 10.5 0.2 2.5 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain TM1586_NiRdase PF14512.6 KIY51092.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative TM nitroreductase Plavaka PF18759.1 KIY51094.1 - 4e-57 193.9 0.1 4.4e-57 193.7 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase zf-ANAPC11 PF12861.7 KIY51094.1 - 0.7 10.0 6.0 0.18 11.8 2.6 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Plavaka PF18759.1 KIY51095.1 - 1.8e-13 50.5 2.0 2.1e-12 46.9 1.3 2.1 2 0 0 2 2 2 2 Plavaka transposase DUF3741 PF12552.8 KIY51095.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) UQ_con PF00179.26 KIY51098.1 - 1.6e-19 70.0 0.0 2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY51098.1 - 0.0033 17.7 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain zf-RING_7 PF02591.15 KIY51098.1 - 0.13 12.5 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 C4-type zinc ribbon domain WD40 PF00400.32 KIY51101.1 - 2.8e-25 88.1 16.7 3e-10 40.5 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY51101.1 - 4e-09 36.6 0.0 0.0018 18.5 0.0 4.2 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY51101.1 - 0.0015 17.5 0.0 0.024 13.6 0.0 2.6 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SnoaL_2 PF12680.7 KIY51102.1 - 0.0072 17.0 0.0 0.015 15.9 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like domain PIN_4 PF13638.6 KIY51103.1 - 2.6e-17 63.3 0.1 6.4e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 KIY51103.1 - 5.8e-12 45.7 0.0 1e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain PIN_12 PF16289.5 KIY51103.1 - 0.046 14.2 0.2 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 PIN domain NYN PF01936.18 KIY51104.1 - 2.1e-09 38.0 0.0 8.4e-09 36.1 0.0 1.9 2 1 0 2 2 2 1 NYN domain NYN PF01936.18 KIY51105.1 - 4.2e-06 27.3 0.0 4.6e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 NYN domain DUF3638 PF12340.8 KIY51106.1 - 2.7e-83 278.7 0.1 6.1e-83 277.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIY51106.1 - 2.3e-16 58.9 0.1 6.7e-16 57.4 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF932 PF06067.11 KIY51106.1 - 0.029 14.1 0.9 0.099 12.4 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF932) YARHG PF13308.6 KIY51106.1 - 0.16 11.9 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 YARHG domain BCS1_N PF08740.11 KIY51107.1 - 2.7e-42 144.9 6.0 2.7e-42 144.9 6.0 2.4 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KIY51107.1 - 9.4e-15 55.2 0.0 1.8e-12 47.8 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIY51107.1 - 0.0008 19.6 3.3 0.005 17.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIY51107.1 - 0.0058 16.4 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KIY51107.1 - 0.0058 17.0 0.2 0.0058 17.0 0.2 2.6 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KIY51107.1 - 0.0072 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KIY51107.1 - 0.01 15.8 0.1 0.071 13.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIY51107.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIY51107.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KIY51107.1 - 0.078 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KIY51107.1 - 0.089 13.3 0.0 0.089 13.3 0.0 2.9 2 1 0 2 2 1 0 AAA domain BUD22 PF09073.10 KIY51107.1 - 0.1 12.0 40.3 0.035 13.4 34.5 2.1 2 0 0 2 2 2 0 BUD22 Ferlin_C PF16165.5 KIY51107.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.5 2 1 1 3 3 2 0 Ferlin C-terminus NACHT PF05729.12 KIY51107.1 - 0.13 12.2 0.1 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 NACHT domain NDK PF00334.19 KIY51108.1 - 2.8e-53 179.5 0.0 3.2e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UCR_14kD PF02271.16 KIY51109.1 - 6.1e-39 132.0 0.2 7.1e-39 131.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.21 KIY51110.1 - 7e-147 488.7 0.0 9.4e-147 488.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KIY51110.1 - 3.6e-42 144.0 0.0 7.4e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIY51110.1 - 7.4e-14 51.7 0.0 2.2e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KIY51110.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KIY51110.1 - 0.0021 17.1 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component CTP_transf_like PF01467.26 KIY51111.1 - 0.18 12.0 0.0 0.52 10.5 0.0 1.9 1 1 0 1 1 1 0 Cytidylyltransferase-like ERAP1_C PF11838.8 KIY51112.1 - 5.2e-69 233.2 0.1 1.1e-68 232.1 0.1 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KIY51112.1 - 5.3e-51 173.3 0.0 1.1e-50 172.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIY51112.1 - 8.4e-46 156.5 0.1 1.9e-44 152.1 0.1 2.3 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Pox_MCEL PF03291.16 KIY51113.1 - 2.7e-88 296.3 0.0 3.8e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KIY51113.1 - 1e-11 45.4 0.0 1.7e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY51113.1 - 6.5e-09 35.8 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY51113.1 - 4.6e-08 33.7 0.0 7.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY51113.1 - 4.8e-08 32.9 0.0 7.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY51113.1 - 8e-07 29.6 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KIY51113.1 - 0.0002 20.6 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.14 KIY51113.1 - 0.0073 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain HECT PF00632.25 KIY51114.1 - 2.2e-94 316.4 0.0 3.5e-94 315.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KIY51114.1 - 8e-37 125.0 19.6 9.6e-13 48.0 6.3 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KIY51114.1 - 1.8e-20 73.2 0.2 4.8e-20 71.8 0.2 1.7 1 0 0 1 1 1 1 C2 domain DUF2383 PF09537.10 KIY51115.1 - 0.022 15.1 5.1 0.071 13.5 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) DUF1640 PF07798.11 KIY51115.1 - 0.031 14.3 1.5 0.045 13.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Umbravirus_LDM PF04817.12 KIY51115.1 - 0.2 11.0 4.6 0.13 11.6 0.2 2.4 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family Cnn_1N PF07989.11 KIY51115.1 - 0.47 10.6 14.8 0.095 12.9 0.9 3.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 zf-C4H2 PF10146.9 KIY51115.1 - 0.98 9.7 8.8 1.3 9.3 1.2 3.0 3 0 0 3 3 3 0 Zinc finger-containing protein GAS PF13851.6 KIY51115.1 - 2.7 7.3 17.9 0.31 10.4 2.3 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KIY51115.1 - 8 6.6 8.3 8 6.6 0.3 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Med21 PF11221.8 KIY51115.1 - 9.4 6.5 10.1 2.9 8.2 1.3 3.5 3 1 0 3 3 3 0 Subunit 21 of Mediator complex Mog1 PF04603.12 KIY51117.1 - 3.4e-30 105.2 0.0 4.2e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ndc80_HEC PF03801.13 KIY51118.1 - 2.9e-28 98.4 0.0 8.4e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 HEC/Ndc80p family Spc7 PF08317.11 KIY51118.1 - 1.9 7.3 27.6 0.088 11.7 6.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Ntox1 PF15500.6 KIY51118.1 - 6.3 7.2 9.0 1.7 9.0 2.3 3.2 2 1 1 3 3 3 0 Putative RNase-like toxin, toxin_1 DUF2781 PF10914.8 KIY51119.1 - 3.3e-33 115.2 7.1 3.8e-33 115.0 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Spindle_Spc25 PF08234.12 KIY51120.1 - 1.7e-17 63.3 0.0 6.5e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 KIY51120.1 - 0.00014 20.9 7.4 0.00019 20.4 7.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein EMP24_GP25L PF01105.24 KIY51120.1 - 0.0052 16.7 5.0 2.1 8.2 0.0 2.3 2 1 0 2 2 2 2 emp24/gp25L/p24 family/GOLD MutS_III PF05192.18 KIY51120.1 - 0.014 15.7 0.6 0.018 15.3 0.6 1.3 1 0 0 1 1 1 0 MutS domain III FapA PF03961.13 KIY51120.1 - 0.036 12.7 3.6 0.043 12.4 3.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 KIY51120.1 - 0.046 14.3 7.1 0.071 13.8 1.0 2.2 1 1 1 2 2 2 0 Initiation control protein YabA PDCD2_C PF04194.13 KIY51120.1 - 0.078 13.0 3.1 0.11 12.6 3.1 1.1 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain DUF724 PF05266.14 KIY51120.1 - 0.084 12.7 6.9 0.14 12.0 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 KIY51120.1 - 0.099 12.1 11.7 0.14 11.6 11.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4472 PF14739.6 KIY51120.1 - 0.15 12.8 11.0 0.22 12.2 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DUF4200 PF13863.6 KIY51120.1 - 0.15 12.4 18.2 0.063 13.7 14.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BST2 PF16716.5 KIY51120.1 - 0.15 12.6 8.9 0.27 11.9 8.9 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Exonuc_VII_L PF02601.15 KIY51120.1 - 0.59 9.6 5.5 0.77 9.3 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 KIY51120.1 - 1.1 8.5 9.9 1.5 8.0 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BRE1 PF08647.11 KIY51120.1 - 2.1 8.5 14.2 0.82 9.8 5.6 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 KIY51120.1 - 2.5 8.1 12.2 3.9 7.5 12.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 KIY51120.1 - 2.6 8.5 11.8 0.44 11.0 5.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.13 KIY51120.1 - 3.2 6.9 4.8 4.5 6.4 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin-6_N PF09177.11 KIY51120.1 - 3.7 8.2 10.6 7.2 7.2 3.9 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FemAB PF02388.16 KIY51120.1 - 4.4 6.1 6.3 5.7 5.7 6.3 1.1 1 0 0 1 1 1 0 FemAB family GrpE PF01025.19 KIY51120.1 - 5.9 6.5 11.2 1.5 8.5 7.5 1.8 1 1 0 1 1 1 0 GrpE PALP PF00291.25 KIY51121.1 - 5.2e-59 200.1 0.0 6.5e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AIRC PF00731.20 KIY51121.1 - 0.044 13.4 0.4 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 AIR carboxylase Myosin_head PF00063.21 KIY51122.1 - 1.4e-258 859.7 0.0 2.6e-258 858.8 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KIY51122.1 - 5.9e-26 90.8 6.2 6.6e-26 90.6 1.1 3.3 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 KIY51122.1 - 2e-08 33.3 35.4 0.00046 19.7 1.0 7.3 7 0 0 7 7 7 5 IQ calmodulin-binding motif AAA_22 PF13401.6 KIY51122.1 - 0.0016 18.7 0.0 0.0079 16.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain Myosin_N PF02736.19 KIY51122.1 - 0.031 14.1 0.1 0.07 13.0 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain ING PF12998.7 KIY51122.1 - 0.068 13.8 5.4 0.33 11.6 5.4 2.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding AAA_16 PF13191.6 KIY51122.1 - 0.44 10.9 0.0 0.44 10.9 0.0 3.9 2 1 1 3 3 3 0 AAA ATPase domain EIF4E-T PF10477.9 KIY51122.1 - 0.82 8.4 8.1 1.3 7.8 8.1 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Fib_alpha PF08702.10 KIY51122.1 - 2 8.6 13.4 0.38 10.9 7.9 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Rad51 PF08423.11 KIY51123.1 - 1.5e-10 40.8 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 DnaB_C PF03796.15 KIY51123.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Hid1 PF12722.7 KIY51124.1 - 1.7e-178 595.4 0.0 2.1e-178 595.1 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KIY51124.1 - 5.4e-91 305.9 0.0 7.1e-91 305.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF1590 PF07629.11 KIY51124.1 - 2.5 8.0 4.1 5.8 6.8 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) Band_7 PF01145.25 KIY51125.1 - 2.9e-06 27.4 0.0 2.9e-06 27.4 0.0 3.2 2 2 1 3 3 3 1 SPFH domain / Band 7 family TBPIP_N PF15517.6 KIY51125.1 - 0.23 11.5 2.3 2.3 8.3 0.1 2.8 2 0 0 2 2 2 0 TBP-interacting protein N-terminus WPP PF13943.6 KIY51125.1 - 0.49 10.8 6.9 1 9.8 6.9 1.5 1 0 0 1 1 1 0 WPP domain DSHCT PF08148.12 KIY51126.1 - 1.6e-50 171.0 0.1 3.3e-50 169.9 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KIY51126.1 - 5.3e-31 107.2 0.0 1.1e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KIY51126.1 - 3.3e-25 89.5 0.0 5.2e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KIY51126.1 - 1.6e-18 67.1 0.1 2.9e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY51126.1 - 9e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY51126.1 - 2.6e-05 24.5 0.0 8.7e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 KIY51126.1 - 0.023 13.8 0.5 0.042 12.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) ATPase_2 PF01637.18 KIY51126.1 - 0.09 12.7 0.1 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIY51126.1 - 0.11 12.7 0.0 0.4 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Atg8 PF02991.16 KIY51127.1 - 6.3e-52 174.1 0.2 7.5e-52 173.9 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KIY51127.1 - 4e-07 30.3 0.0 5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_2 PF07653.17 KIY51127.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.4 1 1 0 1 1 1 0 Variant SH3 domain NAD_binding_8 PF13450.6 KIY51128.1 - 0.00024 21.2 1.3 0.0006 20.0 1.2 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIY51128.1 - 0.0092 15.3 0.5 0.01 15.1 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KIY51128.1 - 0.11 11.7 0.2 0.14 11.4 0.2 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KIY51128.1 - 0.15 11.2 0.2 0.2 10.9 0.2 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY51128.1 - 0.17 11.5 2.8 0.22 11.1 2.8 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase PBP PF01161.20 KIY51130.1 - 5e-11 43.0 0.0 6.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein G-patch PF01585.23 KIY51131.1 - 9e-12 44.7 1.5 1.6e-11 43.9 1.5 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KIY51131.1 - 1.4e-10 40.8 0.1 3.5e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KIY51131.1 - 2.5e-05 24.3 1.0 8e-05 22.7 1.0 1.9 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KIY51131.1 - 0.0026 18.0 0.2 0.0051 17.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY51131.1 - 0.07 14.0 0.3 0.16 12.9 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIY51131.1 - 0.15 12.4 0.2 0.29 11.5 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RED_N PF07808.13 KIY51131.1 - 0.23 11.0 5.6 0.038 13.6 0.8 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region zf-C2H2 PF00096.26 KIY51131.1 - 0.23 12.0 0.2 0.49 11.0 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type COQ7 PF03232.13 KIY51134.1 - 7.9e-68 227.6 0.2 8.9e-68 227.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin_2 PF13668.6 KIY51134.1 - 0.0055 16.9 0.1 0.76 10.0 0.1 2.3 1 1 1 2 2 2 2 Ferritin-like domain AurF PF11583.8 KIY51134.1 - 0.0068 15.7 1.5 0.0098 15.2 1.5 1.1 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF Rubrerythrin PF02915.17 KIY51134.1 - 0.03 14.7 0.0 0.42 11.0 0.0 2.1 1 1 1 2 2 2 0 Rubrerythrin Ferritin PF00210.24 KIY51134.1 - 0.043 13.8 0.4 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 Ferritin-like domain GARP PF16731.5 KIY51134.1 - 0.088 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF3849 PF12960.7 KIY51134.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) Pkinase PF00069.25 KIY51135.1 - 4e-64 216.5 0.0 4.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51135.1 - 2.6e-24 85.9 0.0 3.6e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY51135.1 - 0.00021 21.3 0.0 0.021 14.8 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY51135.1 - 0.00036 19.9 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KIY51135.1 - 0.0018 17.9 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 KIY51135.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY51135.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DeoC PF01791.9 KIY51136.1 - 2.9e-12 46.7 5.3 3.8e-12 46.3 5.3 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 KIY51136.1 - 0.0053 16.2 0.1 0.0079 15.7 0.1 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein DAO PF01266.24 KIY51137.1 - 1.3e-36 126.9 0.2 1.6e-36 126.7 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY51137.1 - 7.9e-07 29.2 0.1 2.3e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIY51137.1 - 4.4e-05 22.8 0.1 9.2e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIY51137.1 - 0.0033 16.7 0.2 0.029 13.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY51137.1 - 0.019 13.7 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Ion_trans_2 PF07885.16 KIY51137.1 - 0.036 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Ion channel FAD_binding_2 PF00890.24 KIY51137.1 - 0.054 12.6 0.2 0.11 11.5 0.1 1.4 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KIY51137.1 - 0.075 13.0 0.4 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIY51137.1 - 0.09 11.8 0.0 0.2 10.6 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KIY51137.1 - 0.19 10.9 0.3 0.36 10.0 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain FH2 PF02181.23 KIY51138.1 - 7.1e-77 259.0 4.1 7.1e-77 259.0 4.1 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KIY51138.1 - 4.2e-37 127.7 0.6 4.2e-37 127.7 0.6 2.5 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KIY51138.1 - 3.9e-36 124.4 0.0 3.9e-36 124.4 0.0 2.6 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Syntaxin_2 PF14523.6 KIY51138.1 - 0.013 15.9 11.1 5.5 7.4 5.0 4.3 3 0 0 3 3 3 0 Syntaxin-like protein SseC PF04888.12 KIY51138.1 - 0.13 11.9 3.2 0.49 10.0 3.2 2.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Baculo_PEP_C PF04513.12 KIY51138.1 - 6.9 6.7 8.1 3.9 7.5 0.8 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KIY51138.1 - 8.3 6.5 14.2 8.4 6.5 4.2 4.3 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) Pkinase_Tyr PF07714.17 KIY51139.1 - 8.8e-41 139.9 0.0 1.4e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY51139.1 - 8.7e-38 130.2 0.0 1.7e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 KIY51139.1 - 6.7e-20 72.0 0.2 1.8e-19 70.6 0.2 1.8 1 0 0 1 1 1 1 RasGEF domain zf-PARP PF00645.18 KIY51139.1 - 7.8e-18 65.1 0.7 2.6e-17 63.5 0.0 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Kdo PF06293.14 KIY51139.1 - 0.045 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1539 PF07560.11 KIY51139.1 - 0.11 12.5 0.1 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Snf7 PF03357.21 KIY51140.1 - 1.5e-41 141.9 23.1 9e-41 139.3 21.9 1.9 2 0 0 2 2 2 1 Snf7 DUF1002 PF06207.11 KIY51140.1 - 0.89 9.0 6.7 0.1 12.1 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) YlqD PF11068.8 KIY51140.1 - 0.99 9.8 16.7 0.96 9.8 5.6 2.2 1 1 1 2 2 2 0 YlqD protein zf-AN1 PF01428.16 KIY51141.1 - 3e-20 72.1 19.5 1.1e-11 44.6 6.7 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KIY51141.1 - 0.00028 21.1 13.8 0.00042 20.5 2.4 2.4 1 1 1 2 2 2 2 IBR domain, a half RING-finger domain zf-RING_7 PF02591.15 KIY51141.1 - 0.068 13.4 1.8 2.3 8.5 0.4 2.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain DUF2180 PF09947.9 KIY51141.1 - 0.11 12.5 5.1 1.4 8.9 0.3 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) FYDLN_acid PF09538.10 KIY51141.1 - 3.5 8.4 6.9 4.7 7.9 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-HIT PF04438.16 KIY51141.1 - 6.8 6.7 12.1 4.4 7.3 4.2 2.8 2 0 0 2 2 2 0 HIT zinc finger Fungal_trans PF04082.18 KIY51142.1 - 2e-12 46.7 1.0 2e-12 46.7 1.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY51142.1 - 0.0016 18.5 11.2 0.003 17.7 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COG4 PF08318.12 KIY51144.1 - 7.3e-87 291.6 0.0 1.5e-86 290.5 0.0 1.6 2 0 0 2 2 2 1 COG4 transport protein Pkip-1 PF06878.11 KIY51144.1 - 0.18 11.9 0.1 0.8 9.8 0.1 2.0 2 0 0 2 2 2 0 Pkip-1 protein Mis14 PF08641.12 KIY51145.1 - 0.03 14.6 0.7 0.03 14.6 0.7 1.9 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Gar1 PF04410.14 KIY51146.1 - 1.7e-36 125.3 0.0 2.1e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.29 KIY51147.1 - 7.7e-63 210.8 0.0 7.1e-45 152.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY51147.1 - 1.4e-07 32.0 0.0 0.0064 16.9 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KIY51147.1 - 1.9e-07 31.2 0.1 0.025 14.6 0.1 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KIY51147.1 - 5e-07 30.3 0.0 0.018 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KIY51147.1 - 1.8e-06 27.8 0.0 0.0044 16.8 0.0 3.1 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KIY51147.1 - 2.1e-05 24.2 1.6 0.0013 18.5 0.0 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 KIY51147.1 - 3.7e-05 24.0 0.5 0.027 14.7 0.1 3.7 3 1 1 4 4 3 1 AAA domain AAA_14 PF13173.6 KIY51147.1 - 8.4e-05 22.6 0.0 0.53 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KIY51147.1 - 0.00017 21.5 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIY51147.1 - 0.00018 21.7 0.0 0.37 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KIY51147.1 - 0.00027 20.3 0.0 0.017 14.3 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 KIY51147.1 - 0.00028 21.2 0.0 0.1 13.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KIY51147.1 - 0.00086 19.1 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KIY51147.1 - 0.0018 18.4 0.0 0.0062 16.7 0.0 1.9 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KIY51147.1 - 0.0021 17.6 0.1 0.012 15.2 0.0 2.2 3 1 1 4 4 3 1 AAA domain Mg_chelatase PF01078.21 KIY51147.1 - 0.0021 17.4 0.3 0.041 13.3 0.1 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KIY51147.1 - 0.0036 16.7 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 KaiC Rad17 PF03215.15 KIY51147.1 - 0.0052 16.7 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain Vps4_C PF09336.10 KIY51147.1 - 0.0071 16.3 0.1 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Cytidylate_kin PF02224.18 KIY51147.1 - 0.008 15.9 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase AAA_28 PF13521.6 KIY51147.1 - 0.0085 16.4 0.0 0.7 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY51147.1 - 0.013 15.1 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KIY51147.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SKI PF01202.22 KIY51147.1 - 0.02 15.0 0.1 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase Sigma54_activat PF00158.26 KIY51147.1 - 0.021 14.6 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KIY51147.1 - 0.039 13.4 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KIY51147.1 - 0.067 12.9 0.0 0.18 11.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KIY51147.1 - 0.071 13.0 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIY51147.1 - 0.1 12.5 0.6 3.1 7.7 0.1 3.0 4 0 0 4 4 3 0 NACHT domain DUF815 PF05673.13 KIY51147.1 - 0.15 11.2 0.0 0.77 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF572 PF04502.13 KIY51148.1 - 5.4e-80 269.5 6.4 6.3e-80 269.3 6.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 KIY51148.1 - 0.013 15.4 1.2 0.55 10.2 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Fungal_trans PF04082.18 KIY51149.1 - 3.7e-10 39.3 0.0 5.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF765 PF05570.11 KIY51149.1 - 3.7 7.8 9.2 1.1 9.5 0.1 3.3 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) PhoD PF09423.10 KIY51150.1 - 1.3e-35 123.1 0.7 5.8e-35 120.9 0.7 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase HA2 PF04408.23 KIY51151.1 - 3.5e-13 49.8 0.1 7.9e-13 48.6 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY51151.1 - 1.2e-11 44.9 0.0 2.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIY51151.1 - 4.4e-11 43.0 0.0 9.7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KIY51151.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY51151.1 - 0.00054 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY51151.1 - 0.00081 19.8 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY51151.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KIY51152.1 - 5e-43 146.9 0.0 2e-42 144.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY51152.1 - 3.1e-27 95.1 0.4 1.3e-26 93.2 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY51152.1 - 1.1e-05 25.5 0.4 0.0026 17.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC_4 PF14392.6 KIY51152.1 - 0.013 15.2 1.1 0.029 14.1 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIY51152.1 - 0.016 15.2 1.4 0.029 14.5 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle SAM_DrpA PF18255.1 KIY51152.1 - 0.16 12.3 0.0 0.49 10.7 0.0 1.9 1 0 0 1 1 1 0 DNA processing protein A sterile alpha motif domain zf-CCHC_2 PF13696.6 KIY51152.1 - 0.31 10.9 3.0 0.2 11.5 0.6 1.9 2 0 0 2 2 2 0 Zinc knuckle Lipase_GDSL_3 PF14606.6 KIY51152.1 - 0.67 10.1 0.0 0.67 10.1 0.0 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Ribosomal_L6e PF01159.19 KIY51152.1 - 1.3 9.5 7.6 3.2 8.3 7.6 1.6 1 0 0 1 1 1 0 Ribosomal protein L6e DnaJ_C PF01556.18 KIY51153.1 - 3.9e-39 134.1 0.4 5.1e-39 133.7 0.4 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY51153.1 - 1.3e-20 73.3 0.3 2.2e-20 72.5 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIY51153.1 - 6.5e-17 61.7 18.7 1.1e-16 60.9 18.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KIY51153.1 - 0.00037 20.4 12.9 0.0043 17.0 2.0 2.4 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein RPT PF13446.6 KIY51153.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein HypA PF01155.19 KIY51153.1 - 1.6 8.8 11.0 5.1e+02 0.7 11.0 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 KIY51153.1 - 10 6.2 10.3 1.7 8.7 1.5 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c DUF1690 PF07956.11 KIY51154.1 - 2.3e-31 109.1 2.2 2.7e-31 108.8 2.2 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) FliG_M PF14841.6 KIY51154.1 - 0.0083 16.3 1.0 0.041 14.1 0.8 2.1 1 1 1 2 2 2 1 FliG middle domain zf-C4H2 PF10146.9 KIY51154.1 - 0.33 11.2 2.8 1.7 8.9 2.6 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein DUF630 PF04783.12 KIY51154.1 - 1.1 9.5 3.5 16 5.8 0.7 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF630) PTP_tm PF18861.1 KIY51155.1 - 0.095 12.7 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DAGK_cat PF00781.24 KIY51156.1 - 3.1e-18 65.6 0.0 8.1e-18 64.2 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain JHD PF17811.1 KIY51157.1 - 3.3e-10 40.4 0.0 8.6e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Jumonji helical domain JmjC PF02373.22 KIY51157.1 - 4.3e-09 36.8 1.5 3.5e-08 33.9 1.5 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KIY51157.1 - 0.00041 20.1 0.1 0.0052 16.5 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.29 KIY51157.1 - 0.001 18.9 10.5 0.0017 18.2 10.5 1.4 1 0 0 1 1 1 1 PHD-finger Sel1 PF08238.12 KIY51158.1 - 1.1e-47 159.3 29.5 2.5e-09 37.5 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_14 PF13428.6 KIY51158.1 - 2.7 9.0 13.9 4.1 8.5 0.3 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY51158.1 - 6.8 7.0 14.3 0.3 11.3 3.2 3.8 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 F-box-like PF12937.7 KIY51159.1 - 5.4e-08 32.6 0.4 1.4e-07 31.3 0.4 1.8 1 0 0 1 1 1 1 F-box-like TPR_1 PF00515.28 KIY51159.1 - 3.6e-06 26.6 0.1 0.17 11.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY51159.1 - 3.8e-06 26.6 0.0 0.049 13.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY51159.1 - 0.0012 19.0 1.0 0.52 10.6 0.1 3.3 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY51159.1 - 0.082 13.2 1.6 3.4 8.1 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY51159.1 - 0.17 12.5 0.5 6.7 7.4 0.3 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat KDZ PF18758.1 KIY51160.1 - 6e-10 39.1 3.4 6.5e-10 39.0 3.4 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIY51161.1 - 2.4e-09 37.1 0.8 2.9e-09 36.9 0.8 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Retrotran_gag_2 PF14223.6 KIY51163.1 - 2.4e-09 37.0 0.0 3.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Carbpep_Y_N PF05388.11 KIY51163.1 - 0.036 14.6 0.0 0.071 13.7 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide GARS_C PF02843.16 KIY51165.1 - 0.04 14.2 0.0 0.07 13.4 0.0 1.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain zf-RVT PF13966.6 KIY51166.1 - 6.6e-05 23.5 0.1 8.7e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PNKP-ligase_C PF16536.5 KIY51171.1 - 0.049 13.9 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, C-terminal region FMN_bind PF04205.14 KIY51174.1 - 0.014 16.0 0.2 5.3 7.7 0.1 2.3 2 0 0 2 2 2 0 FMN-binding domain DUF1088 PF06469.11 KIY51174.1 - 0.054 13.2 1.0 0.24 11.1 0.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1088) FYVE PF01363.21 KIY51177.1 - 2.5e-15 56.3 2.6 4.9e-15 55.4 2.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger HET PF06985.11 KIY51179.1 - 6.5e-14 52.5 2.6 1.2e-11 45.1 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SKN1 PF03935.15 KIY51180.1 - 2.4e-29 102.1 0.0 2.6e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Utp14 PF04615.13 KIY51181.1 - 5.1e-194 647.0 58.2 5.1e-194 647.0 58.2 2.3 1 1 0 2 2 2 1 Utp14 protein LicD PF04991.13 KIY51181.1 - 5.6 7.0 11.0 0.11 12.6 0.6 2.9 2 1 0 2 2 2 0 LicD family Glycos_transf_2 PF00535.26 KIY51182.1 - 7.1e-32 110.6 0.0 9.6e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIY51182.1 - 4.4e-14 52.9 0.0 5.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIY51182.1 - 3.2e-05 23.5 0.0 4.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 APH PF01636.23 KIY51183.1 - 1.6e-09 38.0 0.5 2.9e-08 33.9 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY51183.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KIY51183.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Haspin_kinase PF12330.8 KIY51183.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Sel1 PF08238.12 KIY51184.1 - 3.2e-16 59.4 11.1 1.8e-06 28.4 2.1 3.2 3 0 0 3 3 3 3 Sel1 repeat TPR_16 PF13432.6 KIY51184.1 - 0.065 13.9 3.5 0.15 12.7 1.3 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat HA2 PF04408.23 KIY51185.1 - 7.2e-22 77.7 0.0 7.2e-22 77.7 0.0 3.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY51185.1 - 8.9e-16 58.0 0.0 2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY51185.1 - 1.6e-12 47.7 0.0 4.6e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY51185.1 - 3.8e-08 33.3 0.0 9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY51185.1 - 8.4e-05 22.9 0.4 0.00033 21.0 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY51185.1 - 0.0001 22.6 0.1 0.00026 21.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY51185.1 - 0.00019 21.2 1.5 0.00024 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIY51185.1 - 0.00026 20.4 0.0 0.00049 19.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KIY51185.1 - 0.0058 16.6 0.0 3.5 7.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KIY51185.1 - 0.0077 15.3 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 KIY51185.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIY51185.1 - 0.023 14.3 0.5 0.12 11.9 0.5 2.2 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KIY51185.1 - 0.036 14.6 0.2 0.4 11.2 0.0 2.7 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 KIY51185.1 - 0.062 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KIY51185.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KIY51185.1 - 0.079 13.0 0.1 0.45 10.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KIY51185.1 - 0.092 12.2 0.1 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 KIY51185.1 - 0.11 12.8 0.0 0.41 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KIY51185.1 - 0.46 10.6 2.6 0.56 10.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain LSM PF01423.22 KIY51186.1 - 7.3e-07 28.8 0.0 8.9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY51186.1 - 0.036 14.2 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain MGC-24 PF05283.11 KIY51187.1 - 0.39 11.2 6.1 0.57 10.6 6.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RAP1 PF07218.11 KIY51187.1 - 8.8 4.5 8.2 9.2 4.4 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_hydro_115 PF15979.5 KIY51188.1 - 4.8e-127 424.1 0.0 7.5e-127 423.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KIY51188.1 - 7e-49 166.0 0.0 1.6e-48 164.8 0.0 1.6 2 0 0 2 2 2 1 Gylcosyl hydrolase family 115 C-terminal domain S_layer_C PF05124.12 KIY51188.1 - 0.048 13.6 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region Actin PF00022.19 KIY51189.1 - 5.3e-42 143.9 0.0 1.4e-24 86.5 0.0 2.3 2 0 0 2 2 2 2 Actin DUF3040 PF11239.8 KIY51189.1 - 0.17 12.2 0.2 0.51 10.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Ripply PF14998.6 KIY51189.1 - 0.59 10.8 3.4 1.2 9.9 0.0 2.8 2 0 0 2 2 2 0 Transcription Regulator Ras PF00071.22 KIY51190.1 - 9.6e-64 213.9 0.0 1.1e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY51190.1 - 6.3e-34 116.8 0.1 1e-33 116.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY51190.1 - 1.1e-14 54.2 0.1 1.4e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY51190.1 - 3.9e-06 26.6 0.1 9e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIY51190.1 - 3.3e-05 23.4 0.0 3.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KIY51190.1 - 5.4e-05 23.2 0.1 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIY51190.1 - 9.9e-05 22.4 0.0 0.00024 21.2 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY51190.1 - 0.0049 16.4 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 KIY51190.1 - 0.018 15.5 0.0 0.027 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KIY51190.1 - 0.035 13.9 0.1 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRPRB PF09439.10 KIY51190.1 - 0.052 13.0 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 KIY51190.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 KIY51190.1 - 0.066 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Septin AAA PF00004.29 KIY51190.1 - 0.094 13.1 0.0 0.71 10.3 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 KIY51190.1 - 0.13 11.3 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain F-box-like PF12937.7 KIY51192.1 - 1.3e-07 31.4 0.5 2.4e-07 30.5 0.5 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY51192.1 - 2e-05 24.3 0.1 3.3e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 F-box domain VHS PF00790.19 KIY51193.1 - 1.7e-44 151.1 1.4 5.5e-43 146.2 0.1 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KIY51193.1 - 4.8e-17 61.8 8.5 8e-17 61.1 8.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KIY51193.1 - 0.00029 20.5 15.8 0.012 15.5 3.6 2.8 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KIY51193.1 - 0.0013 18.9 4.4 0.003 17.7 4.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 KIY51193.1 - 0.019 14.8 2.6 0.019 14.8 2.6 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 KIY51193.1 - 3.1 8.2 8.2 5.3 7.5 7.5 1.8 1 1 0 1 1 1 0 Ring finger domain DZR PF12773.7 KIY51193.1 - 4.3 7.4 9.4 51 4.0 8.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon F-box-like PF12937.7 KIY51195.1 - 0.0062 16.4 0.0 0.022 14.6 0.0 2.0 1 1 0 1 1 1 1 F-box-like Nic96 PF04097.14 KIY51196.1 - 4.2e-151 504.5 1.3 5.4e-151 504.1 1.3 1.1 1 0 0 1 1 1 1 Nup93/Nic96 T2SSF PF00482.23 KIY51196.1 - 0.019 14.9 0.1 0.16 11.9 0.0 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Alpha_TIF PF02232.15 KIY51196.1 - 0.069 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) DNAPolymera_Pol PF11590.8 KIY51198.1 - 0.095 12.6 1.6 0.66 9.9 0.2 2.4 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol DUF5134 PF17197.4 KIY51198.1 - 0.85 9.5 4.5 19 5.1 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) APH PF01636.23 KIY51200.1 - 2.2e-15 57.2 0.0 3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY51200.1 - 3.5e-06 26.7 0.0 6.4e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Baculo_VP1054 PF05789.11 KIY51201.1 - 0.0065 15.7 0.3 0.0087 15.3 0.3 1.1 1 0 0 1 1 1 1 Baculovirus VP1054 protein CAP_N PF01213.19 KIY51202.1 - 7.8 5.9 15.3 2 7.8 1.3 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_carr PF00153.27 KIY51203.1 - 8.2e-66 218.0 1.7 1.9e-22 78.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C3HC PF07967.13 KIY51204.1 - 7.7e-26 90.7 0.1 6.1e-23 81.3 0.2 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KIY51204.1 - 9.7e-15 54.5 2.3 2.4e-09 37.2 0.0 3.2 3 0 0 3 3 3 2 Rsm1-like DM PF00751.18 KIY51204.1 - 0.42 10.6 2.1 15 5.6 0.8 2.5 2 0 0 2 2 2 0 DM DNA binding domain DUF5639 PF18690.1 KIY51205.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5639) Glyco_tranf_2_4 PF13704.6 KIY51206.1 - 0.12 12.9 0.2 0.53 10.8 0.1 2.1 2 1 0 2 2 2 0 Glycosyl transferase family 2 MFS_1 PF07690.16 KIY51207.1 - 1.3e-32 113.1 31.3 1.3e-32 113.1 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY51207.1 - 3.8e-11 42.5 12.0 3.8e-11 42.5 12.0 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1129 PF06570.11 KIY51207.1 - 0.049 13.1 0.4 0.049 13.1 0.4 2.7 4 1 0 4 4 4 0 Protein of unknown function (DUF1129) Esterase PF00756.20 KIY51210.1 - 1.1e-40 139.9 0.0 1.2e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KIY51210.1 - 0.0027 16.7 0.0 0.0081 15.1 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Esterase_phd PF10503.9 KIY51210.1 - 0.0085 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KIY51210.1 - 0.083 12.1 0.2 0.19 11.0 0.2 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Kelch_3 PF13415.6 KIY51211.1 - 7.6e-32 109.0 11.7 4.3e-08 33.2 0.0 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KIY51211.1 - 1.3e-31 108.3 10.6 3.1e-07 30.3 0.3 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KIY51211.1 - 3e-28 97.3 2.1 2.7e-05 24.0 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KIY51211.1 - 1.1e-24 85.8 9.6 6e-09 35.9 0.4 6.5 3 2 3 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KIY51211.1 - 9.2e-22 76.4 6.5 9.3e-06 25.1 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KIY51211.1 - 5.1e-21 73.8 9.7 0.0013 18.6 0.2 6.6 6 0 0 6 6 6 6 Kelch motif DUF3972 PF13118.6 KIY51211.1 - 0.0022 18.4 3.2 0.011 16.2 3.2 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) Shugoshin_N PF07558.11 KIY51211.1 - 0.045 13.6 14.7 4.4 7.3 0.0 5.3 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Vac_Fusion PF02346.16 KIY51211.1 - 0.58 9.8 7.5 19 4.9 0.5 4.9 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 RTBV_P46 PF06216.11 KIY51211.1 - 0.78 8.6 3.5 0.35 9.7 0.1 2.1 3 0 0 3 3 3 0 Rice tungro bacilliform virus P46 protein PIN_2 PF10130.9 KIY51211.1 - 0.93 9.7 4.1 1.4 9.2 1.2 2.9 2 0 0 2 2 2 0 PIN domain S1 PF00575.23 KIY51212.1 - 1.7e-56 188.5 31.8 8.2e-11 42.1 0.4 10.4 10 0 0 10 10 10 10 S1 RNA binding domain NRDE-2 PF08424.10 KIY51212.1 - 4e-08 32.7 3.7 0.00069 18.8 2.7 3.2 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 KIY51212.1 - 1.1e-06 29.1 0.0 0.18 12.3 0.0 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY51212.1 - 2.5e-05 24.7 0.0 0.75 10.8 0.0 5.0 4 1 1 5 5 4 1 Tetratricopeptide repeat Suf PF05843.14 KIY51212.1 - 0.00059 19.9 0.1 0.00059 19.9 0.1 3.9 3 1 2 5 5 5 2 Suppressor of forked protein (Suf) ANAPC3 PF12895.7 KIY51212.1 - 0.0011 19.2 0.1 0.0045 17.2 0.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 S1_2 PF13509.6 KIY51212.1 - 0.0016 18.4 0.4 15 5.7 0.0 4.8 4 0 0 4 4 4 0 S1 domain RNA_pol_Rbc25 PF08292.12 KIY51212.1 - 0.0044 17.3 0.2 5.1 7.4 0.0 4.9 3 1 0 4 4 4 1 RNA polymerase III subunit Rpc25 TPR_12 PF13424.6 KIY51212.1 - 0.0079 16.5 0.4 5.1 7.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY51212.1 - 0.026 14.6 0.0 1.9 8.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 KIY51212.1 - 0.042 13.0 2.1 0.57 9.3 0.4 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat CsrA PF02599.16 KIY51212.1 - 0.076 13.0 2.0 39 4.3 0.0 3.9 4 0 0 4 4 4 0 Global regulator protein family TPR_7 PF13176.6 KIY51212.1 - 0.12 12.4 0.1 3.3 8.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY51212.1 - 0.15 12.7 0.0 18 6.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SF3A2 PF16835.5 KIY51213.1 - 8e-36 122.3 0.1 1.2e-35 121.7 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KIY51213.1 - 1.9e-06 28.0 0.7 1.9e-06 28.0 0.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KIY51213.1 - 0.014 14.9 0.9 0.026 14.1 0.9 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 KIY51213.1 - 0.039 13.9 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein MRP-S25 PF13741.6 KIY51214.1 - 7.8e-45 153.2 3.6 3.6e-43 147.8 3.6 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KIY51214.1 - 0.28 11.4 3.5 1.3 9.3 3.2 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 PCI PF01399.27 KIY51215.1 - 5.7e-17 62.2 0.1 2.7e-16 60.0 0.0 2.2 3 0 0 3 3 3 1 PCI domain RPN5_C PF18098.1 KIY51215.1 - 8.5e-06 25.8 3.2 1.9e-05 24.6 3.2 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain YvbH_ext PF11724.8 KIY51215.1 - 0.16 12.3 0.2 38 4.7 0.1 2.8 2 0 0 2 2 2 0 YvbH-like oligomerisation region F-box-like PF12937.7 KIY51216.1 - 0.14 12.0 0.1 0.14 12.0 0.1 3.2 4 0 0 4 4 4 0 F-box-like PA28_beta PF02252.18 KIY51218.1 - 7e-37 126.3 0.1 8.7e-37 126.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit WD40 PF00400.32 KIY51219.1 - 1.1e-14 54.6 12.5 4.4e-05 24.2 0.3 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KIY51219.1 - 1.1e-14 54.4 0.7 9.3e-14 51.4 0.0 2.8 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KIY51219.1 - 3.6e-05 24.0 0.1 0.058 13.7 0.0 2.8 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KIY51219.1 - 0.26 9.2 0.9 2 6.3 0.0 2.3 2 1 0 3 3 3 0 IKI3 family Oxidored_FMN PF00724.20 KIY51220.1 - 1.9e-62 211.5 0.0 2.5e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KIY51220.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) ComA PF02679.15 KIY51220.1 - 0.16 11.4 0.1 0.95 8.9 0.0 1.9 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) MAPEG PF01124.18 KIY51221.1 - 5.8e-12 45.6 0.1 1.6e-11 44.2 0.1 1.6 1 1 0 1 1 1 1 MAPEG family ZYG-11_interact PF05884.12 KIY51221.1 - 0.0098 15.3 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Interactor of ZYG-11 Ank_2 PF12796.7 KIY51223.1 - 2.4e-08 34.4 0.0 4.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY51223.1 - 1.2e-07 31.8 0.0 6.1e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-CCCH_2 PF14608.6 KIY51223.1 - 1e-06 29.0 20.2 1.2e-05 25.6 6.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Ank_4 PF13637.6 KIY51223.1 - 2.1e-06 28.1 0.0 4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KIY51223.1 - 8e-06 26.1 0.0 0.0018 18.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH_4 PF18044.1 KIY51223.1 - 2e-05 24.3 14.0 0.0005 19.8 2.1 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KIY51223.1 - 2.2e-05 25.1 2.2 7.8e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 KIY51223.1 - 0.0002 21.3 2.0 0.0002 21.3 2.0 2.7 3 0 0 3 3 3 2 Zinc finger domain Ank_3 PF13606.6 KIY51223.1 - 0.00081 19.7 0.0 0.017 15.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH PF00642.24 KIY51223.1 - 0.0038 17.1 9.9 0.0067 16.3 1.6 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KIY51223.1 - 0.078 13.2 1.2 1.2 9.4 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger containing family NAD_Gly3P_dh_C PF07479.14 KIY51224.1 - 2.4e-50 170.5 0.2 3.6e-50 169.9 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KIY51224.1 - 4.4e-33 114.5 0.0 8.3e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KIY51224.1 - 8.7e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KIY51224.1 - 3.3e-05 24.4 0.0 9.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIY51224.1 - 0.00089 19.5 0.0 0.0071 16.5 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KIY51224.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 KIY51224.1 - 0.11 12.8 0.0 5.1 7.4 0.0 2.8 4 0 0 4 4 4 0 TrkA-N domain Shikimate_DH PF01488.20 KIY51224.1 - 0.13 12.3 0.0 0.47 10.5 0.0 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SNARE PF05739.19 KIY51225.1 - 3.8e-12 46.0 0.1 1.3e-11 44.3 0.1 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KIY51225.1 - 2.5e-07 29.8 0.5 2.5e-07 29.8 0.5 2.3 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KIY51225.1 - 0.00026 20.8 1.0 0.00026 20.8 1.0 3.2 2 1 0 3 3 3 1 Syntaxin Syntaxin-18_N PF10496.9 KIY51225.1 - 0.00052 20.2 0.9 0.00052 20.2 0.9 2.6 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus BLOC1_2 PF10046.9 KIY51225.1 - 0.14 12.5 11.0 0.26 11.6 0.3 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KIY51225.1 - 0.16 12.5 0.3 0.16 12.5 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 KxDL PF10241.9 KIY51225.1 - 0.22 11.8 11.4 0.38 11.1 1.9 3.6 2 2 1 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 KIY51225.1 - 1.8 8.6 12.0 1.7 8.7 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 KIY51225.1 - 4.6 7.5 12.3 3.9 7.7 6.4 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein RRM_1 PF00076.22 KIY51226.1 - 0.00013 21.8 0.0 0.00062 19.5 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 KIY51226.1 - 0.35 9.1 2.7 0.43 8.8 2.7 1.1 1 0 0 1 1 1 0 CDC45-like protein GARS_A PF01071.19 KIY51227.1 - 4.1e-77 258.4 0.0 5.9e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KIY51227.1 - 3.2e-32 111.2 0.0 2.8e-31 108.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KIY51227.1 - 2.3e-30 105.8 0.0 4.6e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KIY51227.1 - 2.1e-27 95.2 1.0 5.7e-27 93.8 1.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KIY51227.1 - 7.7e-15 55.3 0.7 4e-14 53.0 1.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KIY51227.1 - 6.4e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KIY51227.1 - 0.00019 21.5 0.0 0.00042 20.4 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KIY51227.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 KIY51227.1 - 0.013 15.0 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KIY51227.1 - 0.077 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp IMS PF00817.20 KIY51229.1 - 3.6e-39 134.2 0.0 7.5e-39 133.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KIY51229.1 - 3.6e-24 85.0 1.9 7.5e-24 84.0 1.9 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KIY51229.1 - 6.7e-16 59.1 0.0 2.4e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KIY51229.1 - 1.5e-10 41.3 0.0 3.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY51229.1 - 3.1e-05 24.3 0.1 8.9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIY51229.1 - 6e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF1805 PF08827.11 KIY51229.1 - 0.0083 16.4 0.0 0.028 14.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1805) IMS_HHH PF11798.8 KIY51229.1 - 0.0092 16.3 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif UBM PF14377.6 KIY51229.1 - 0.04 13.4 9.8 0.64 9.6 0.1 4.2 5 0 0 5 5 5 0 Ubiquitin binding region Cation_efflux PF01545.21 KIY51231.1 - 5.8e-15 55.6 6.3 7.1e-15 55.3 6.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIY51231.1 - 7e-10 38.9 0.1 1.2e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FeS_assembly_P PF01883.19 KIY51231.1 - 0.04 14.1 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein DUF4395 PF14340.6 KIY51231.1 - 2.1 8.7 5.8 0.56 10.5 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Med7 PF05983.11 KIY51232.1 - 7.4e-49 166.4 1.1 8.9e-49 166.2 1.1 1.1 1 0 0 1 1 1 1 MED7 protein Sipho_Gp157 PF05565.11 KIY51232.1 - 0.058 13.4 0.2 0.096 12.7 0.2 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 AMP-binding PF00501.28 KIY51233.1 - 1.5e-84 284.0 0.0 1.9e-84 283.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY51233.1 - 6.5e-17 62.3 0.1 2e-16 60.7 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Drc1-Sld2 PF11719.8 KIY51234.1 - 2.4e-15 57.0 6.0 2.4e-15 57.0 6.0 2.9 1 1 0 2 2 2 1 DNA replication and checkpoint protein DUF2827 PF10933.8 KIY51234.1 - 0.23 10.1 0.1 0.34 9.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Glyco_trans_4_4 PF13579.6 KIY51235.1 - 4.2 7.8 7.8 4 7.9 4.1 2.8 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain DUF3591 PF12157.8 KIY51236.1 - 1.8e-185 616.9 1.6 2.9e-185 616.2 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KIY51236.1 - 0.00016 21.4 2.4 0.00016 21.4 2.4 2.0 2 0 0 2 2 2 1 Zinc knuckle BCA_ABC_TP_C PF12399.8 KIY51236.1 - 0.16 11.9 0.4 0.45 10.5 0.4 1.8 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter RRM_1 PF00076.22 KIY51237.1 - 6.7e-17 61.1 0.0 6.9e-09 35.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_Tnp_IS91 PF14319.6 KIY51238.1 - 0.0018 18.3 3.0 0.0039 17.2 3.0 1.6 1 0 0 1 1 1 1 Transposase zinc-binding domain Cytochrom_CIII PF02085.16 KIY51238.1 - 0.0059 16.9 0.4 0.016 15.6 0.4 1.7 1 0 0 1 1 1 1 Class III cytochrome C family ParA PF10609.9 KIY51240.1 - 2.7e-88 295.6 0.0 3.3e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIY51240.1 - 7.9e-06 26.0 0.0 1.8e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIY51240.1 - 1.2e-05 24.7 0.1 0.00051 19.3 0.0 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 KIY51240.1 - 6e-05 23.0 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KIY51240.1 - 0.0055 16.0 0.0 0.017 14.4 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ NB-ARC PF00931.22 KIY51240.1 - 0.041 13.1 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 KIY51240.1 - 0.097 12.6 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase XPC-binding PF09280.11 KIY51240.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 XPC-binding domain AAA_25 PF13481.6 KIY51240.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIY51240.1 - 0.16 11.9 0.1 6.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GET2 PF08690.10 KIY51241.1 - 0.31 10.7 1.5 0.57 9.8 1.5 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Rrn6 PF10214.9 KIY51241.1 - 9.5 4.6 14.7 0.092 11.2 6.1 1.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor LRR_6 PF13516.6 KIY51242.1 - 0.038 14.0 9.7 0.28 11.3 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Antimicrobial25 PF16839.5 KIY51242.1 - 0.73 10.0 2.5 17 5.6 1.1 3.0 3 0 0 3 3 3 0 Nematode antimicrobial peptide Rep_fac_C PF08542.11 KIY51243.1 - 1.4e-25 89.5 0.0 3.4e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KIY51243.1 - 2.2e-12 47.1 0.1 1.6e-10 41.0 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KIY51243.1 - 5.8e-12 46.2 0.0 1.2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KIY51243.1 - 1.4e-06 28.4 0.0 3.7e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIY51243.1 - 1.2e-05 25.6 0.1 0.011 15.9 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KIY51243.1 - 1.4e-05 25.5 0.0 0.001 19.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KIY51243.1 - 2.7e-05 24.0 0.0 6.7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KIY51243.1 - 3.2e-05 23.8 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KIY51243.1 - 8.2e-05 22.4 0.0 0.00017 21.5 0.0 1.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.13 KIY51243.1 - 0.00043 20.1 0.1 0.00064 19.5 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KIY51243.1 - 0.0026 17.7 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain MeaB PF03308.16 KIY51243.1 - 0.0032 16.5 0.0 0.0081 15.2 0.0 1.6 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KIY51243.1 - 0.0042 16.5 0.0 0.049 13.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 KIY51243.1 - 0.0097 16.2 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_11 PF13086.6 KIY51243.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PrpR_N PF06506.11 KIY51243.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Propionate catabolism activator AAA_24 PF13479.6 KIY51243.1 - 0.03 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIY51243.1 - 0.047 13.6 0.2 0.16 11.9 0.1 1.9 1 1 1 2 2 2 0 NTPase KTI12 PF08433.10 KIY51243.1 - 0.05 13.0 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 KIY51243.1 - 0.054 13.8 0.2 0.17 12.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIY51243.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KIY51243.1 - 0.067 13.7 0.0 0.14 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIY51243.1 - 0.07 13.5 0.1 0.34 11.3 0.1 2.2 1 1 0 1 1 1 0 RNA helicase HEAT_2 PF13646.6 KIY51243.1 - 0.11 12.9 0.0 0.95 9.9 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats TniB PF05621.11 KIY51243.1 - 0.13 11.6 0.0 6.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 KIY51243.1 - 0.14 11.9 0.0 0.39 10.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain YflT PF11181.8 KIY51243.1 - 0.16 12.5 0.0 0.49 10.9 0.0 1.8 2 0 0 2 2 1 0 Heat induced stress protein YflT ABC_tran PF00005.27 KIY51243.1 - 0.17 12.4 0.1 0.51 10.8 0.1 1.6 1 1 0 1 1 1 0 ABC transporter tRNA-synt_2b PF00587.25 KIY51244.1 - 1.3e-19 70.9 0.0 2.1e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIY51244.1 - 1.4e-06 28.5 4.8 2.6e-06 27.6 4.8 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Lzipper-MIP1 PF14389.6 KIY51244.1 - 0.00016 21.9 1.1 0.0004 20.6 1.1 1.6 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Glyoxalase PF00903.25 KIY51245.1 - 1.7e-23 83.2 0.2 2.1e-23 82.9 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KIY51245.1 - 4.5e-08 33.3 0.0 0.00041 20.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIY51245.1 - 4e-07 30.8 0.0 5.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KIY51245.1 - 0.00016 21.9 0.0 0.00073 19.7 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 KIY51245.1 - 0.03 14.4 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal Glyoxalase_2 PF12681.7 KIY51245.1 - 0.032 14.2 0.0 4 7.4 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase-like domain Myb_DNA-bind_7 PF15963.5 KIY51249.1 - 2.6e-21 75.3 0.0 5.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KIY51249.1 - 2.5e-10 40.4 0.0 5.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY51249.1 - 0.00022 21.4 0.1 0.00041 20.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_6 PF13405.6 KIY51250.1 - 1.4e-12 46.5 0.7 1.8e-05 24.3 0.2 3.2 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KIY51250.1 - 1.6e-10 41.3 1.7 1.9e-05 25.0 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KIY51250.1 - 2.1e-07 30.0 1.1 0.013 15.0 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KIY51250.1 - 0.0009 19.5 0.0 0.57 10.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain DUF2666 PF10869.8 KIY51250.1 - 0.02 15.1 0.0 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) DUF3793 PF12672.7 KIY51250.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3793) EF-hand_5 PF13202.6 KIY51250.1 - 1 9.0 3.4 0.56 9.8 0.4 2.2 3 0 0 3 3 3 0 EF hand VHS PF00790.19 KIY51251.1 - 7.9e-27 93.8 0.0 1.8e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KIY51251.1 - 8.7e-07 29.2 2.2 6.3e-06 26.4 2.1 2.3 2 0 0 2 2 2 1 GAT domain DUF4764 PF15961.5 KIY51251.1 - 0.28 9.8 19.7 0.38 9.4 19.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) U79_P34 PF03064.16 KIY51251.1 - 1.7 8.0 18.7 0.33 10.3 14.5 1.9 2 0 0 2 2 2 0 HSV U79 / HCMV P34 RR_TM4-6 PF06459.12 KIY51251.1 - 3.4 7.4 16.6 0.096 12.5 8.0 2.3 2 1 0 2 2 2 0 Ryanodine Receptor TM 4-6 BT1 PF03092.16 KIY51251.1 - 4.6 5.4 6.0 6.7 4.8 6.0 1.1 1 0 0 1 1 1 0 BT1 family zf-C2H2 PF00096.26 KIY51252.1 - 1.2e-08 35.0 12.0 1.5e-05 25.2 2.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY51252.1 - 9.8e-06 25.8 3.4 9.8e-06 25.8 3.4 3.0 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIY51252.1 - 0.00013 22.1 0.8 0.00013 22.1 0.8 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY51252.1 - 0.00016 22.0 0.6 0.00016 22.0 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIY51252.1 - 0.00019 22.0 1.8 0.00019 22.0 1.8 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIY51252.1 - 0.0027 17.7 1.3 0.0027 17.7 1.3 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIY51252.1 - 0.0069 16.3 1.6 0.022 14.6 1.6 2.0 1 0 0 1 1 1 1 zinc-finger of a C2HC-type FOXP-CC PF16159.5 KIY51252.1 - 0.02 15.5 3.6 0.065 13.9 2.9 1.9 1 1 1 2 2 2 0 FOXP coiled-coil domain RNA_pol_Rpb6 PF01192.22 KIY51254.1 - 1.1e-15 57.2 0.1 1.3e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 adh_short PF00106.25 KIY51255.1 - 1.9e-44 151.5 0.0 2.6e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY51255.1 - 5.7e-30 104.6 0.0 7.4e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIY51255.1 - 2.6e-05 23.8 0.0 0.00044 19.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KIY51255.1 - 5.1e-05 22.8 0.0 8.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KIY51255.1 - 0.0028 17.6 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DFP PF04127.15 KIY51255.1 - 0.061 13.2 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein SIR2 PF02146.17 KIY51256.1 - 2.6e-33 115.4 0.0 7e-22 78.2 0.0 2.1 2 0 0 2 2 2 2 Sir2 family DUF512 PF04459.12 KIY51257.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Sigma54_AID PF00309.20 KIY51257.1 - 0.16 11.8 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) Utp11 PF03998.13 KIY51258.1 - 6.9e-70 235.8 19.1 1e-69 235.2 19.1 1.2 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KIY51258.1 - 0.012 14.9 0.9 0.027 13.8 0.9 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Rad51 PF08423.11 KIY51260.1 - 2.7e-90 302.1 0.0 4.5e-90 301.4 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KIY51260.1 - 1e-10 41.5 0.4 1e-09 38.3 0.4 2.0 1 1 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KIY51260.1 - 0.0094 16.5 0.1 0.028 15.0 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF1565 PF07602.11 KIY51260.1 - 0.014 14.8 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) ATPase PF06745.13 KIY51260.1 - 0.014 14.7 0.1 0.014 14.7 0.1 2.1 3 1 0 3 3 3 0 KaiC RNA_pol_A_CTD PF03118.15 KIY51260.1 - 0.067 12.9 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Ribonuclease_T2 PF00445.18 KIY51261.1 - 1.3e-09 38.6 1.2 2.9e-07 30.9 1.2 2.1 1 1 0 1 1 1 1 Ribonuclease T2 family bZIP_2 PF07716.15 KIY51262.1 - 0.00018 21.5 15.3 0.00029 20.9 15.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY51262.1 - 0.0019 18.3 12.9 0.0033 17.5 12.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor SNF2_N PF00176.23 KIY51263.1 - 8.7e-18 64.2 0.2 4.3e-17 61.9 0.2 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY51263.1 - 5.4e-17 62.1 0.0 1.3e-14 54.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIY51263.1 - 1e-05 24.9 0.1 3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KIY51263.1 - 7.9e-05 22.7 0.1 0.00074 19.6 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit VIGSSK PF14773.6 KIY51263.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal SURF1 PF02104.15 KIY51264.1 - 1.3e-44 152.5 0.1 1.7e-44 152.2 0.1 1.0 1 0 0 1 1 1 1 SURF1 family ANTH PF07651.16 KIY51265.1 - 9.5e-71 238.0 0.0 9.5e-71 238.0 0.0 3.3 2 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.17 KIY51265.1 - 1.8e-54 184.1 12.1 1.8e-54 184.1 12.1 5.9 5 0 0 5 5 5 1 I/LWEQ domain TcdB_N PF12918.7 KIY51265.1 - 0.013 15.8 0.5 0.062 13.6 0.0 2.5 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain FAA_hydro_N_2 PF18288.1 KIY51265.1 - 0.062 13.7 3.7 0.41 11.1 1.0 3.6 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Lip_prot_lig_C PF10437.9 KIY51265.1 - 0.14 12.2 0.6 0.64 10.0 0.6 2.2 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Ion_trans PF00520.31 KIY51267.1 - 3e-05 23.4 2.4 3.6e-05 23.1 2.4 1.1 1 0 0 1 1 1 1 Ion transport protein CWC25 PF12542.8 KIY51268.1 - 1.2e-25 90.4 0.7 1.2e-25 90.4 0.7 2.9 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KIY51268.1 - 1.9e-14 53.5 11.9 1.9e-14 53.5 11.9 4.1 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Glyco_hydro_47 PF01532.20 KIY51269.1 - 3.1e-132 441.8 0.1 3.5e-132 441.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Beta-lactamase PF00144.24 KIY51270.1 - 2.7e-35 122.2 0.0 4e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase RNA_pol_Rpb2_6 PF00562.28 KIY51271.1 - 3.6e-127 424.7 0.1 5.5e-127 424.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIY51271.1 - 1.1e-67 227.5 0.0 1.6e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KIY51271.1 - 7.9e-49 165.9 0.1 1.7e-48 164.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KIY51271.1 - 3.7e-27 94.4 0.5 1.1e-26 92.9 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_7 PF04560.20 KIY51271.1 - 5.5e-26 90.8 0.1 1.6e-25 89.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KIY51271.1 - 6.2e-26 90.4 0.1 1.6e-25 89.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KIY51271.1 - 1.6e-22 79.8 1.4 4.5e-22 78.4 1.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KIY51271.1 - 0.091 13.5 0.1 0.25 12.1 0.1 1.6 1 0 0 1 1 1 0 MRN-interacting protein Lung_7-TM_R PF06814.13 KIY51272.1 - 4.4e-62 210.0 13.3 5.5e-62 209.7 13.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4234 PF14018.6 KIY51272.1 - 0.013 15.6 1.4 0.013 15.6 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) MpPF26 PF07666.11 KIY51272.1 - 0.24 11.5 6.4 0.73 10.0 6.4 1.8 1 0 0 1 1 1 0 M penetrans paralogue family 26 PepSY_TM PF03929.16 KIY51272.1 - 2.2 7.9 8.0 1.2 8.8 3.1 2.4 1 1 1 2 2 2 0 PepSY-associated TM region PX PF00787.24 KIY51273.1 - 1.6e-20 73.2 0.2 8.5e-20 70.8 0.3 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KIY51273.1 - 1.4e-08 34.6 2.0 2.5e-05 23.9 0.9 2.3 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 KIY51273.1 - 0.0045 16.7 0.7 0.024 14.4 0.1 2.2 2 0 0 2 2 2 1 BAR domain of APPL family PEP-utilisers_N PF05524.13 KIY51273.1 - 0.0079 16.4 0.2 0.041 14.1 0.1 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal BAR PF03114.18 KIY51273.1 - 0.037 13.7 4.1 3.1 7.4 0.6 3.4 3 1 0 3 3 3 0 BAR domain HORMA PF02301.18 KIY51274.1 - 2.9e-08 33.6 0.1 4.2e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 HORMA domain Tad_C PF09977.9 KIY51275.1 - 1.1 10.5 4.3 38 5.6 0.0 2.9 3 0 0 3 3 3 0 Putative Tad-like Flp pilus-assembly 3Beta_HSD PF01073.19 KIY51276.1 - 2.7e-12 46.3 0.0 2.5e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIY51276.1 - 2.7e-11 43.4 0.0 7e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY51276.1 - 2.5e-10 39.9 0.0 1.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIY51276.1 - 3.1e-08 33.7 0.0 4.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIY51276.1 - 0.00017 21.9 0.0 0.00047 20.4 0.0 1.8 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KIY51276.1 - 0.0027 17.7 0.0 0.0049 16.8 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KIY51276.1 - 0.0094 15.1 0.0 0.15 11.2 0.0 2.4 2 1 1 3 3 3 1 Male sterility protein NmrA PF05368.13 KIY51276.1 - 0.042 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family B12-binding PF02310.19 KIY51276.1 - 0.16 12.0 0.2 0.58 10.2 0.1 1.9 2 0 0 2 2 2 0 B12 binding domain Glyco_transf_8 PF01501.20 KIY51277.1 - 8e-14 51.8 0.0 1.4e-12 47.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KIY51277.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative ABC1 PF03109.16 KIY51278.1 - 5e-23 81.5 0.0 3.3e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 KIY51278.1 - 0.1 12.5 0.0 0.39 10.6 0.0 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF883 PF05957.13 KIY51279.1 - 0.0022 18.5 11.2 0.036 14.7 0.5 3.0 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF883) Miff PF05644.11 KIY51279.1 - 0.13 11.9 4.4 0.12 12.0 3.7 1.2 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Apolipoprotein PF01442.18 KIY51279.1 - 0.81 9.5 8.7 2.9 7.7 8.6 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain WXG100 PF06013.12 KIY51279.1 - 4.4 7.6 13.8 5.9 7.2 0.3 3.9 3 2 0 3 3 3 0 Proteins of 100 residues with WXG DUF4724 PF15852.5 KIY51280.1 - 1.8 9.1 4.4 5.5 7.5 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4724) Nrap_D4 PF17405.2 KIY51281.1 - 1.3e-50 171.8 0.0 2.3e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KIY51281.1 - 4.1e-40 137.2 0.1 6.6e-36 123.5 0.1 3.0 2 1 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KIY51281.1 - 4.1e-40 137.0 0.0 8.5e-40 136.0 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 KIY51281.1 - 4e-38 130.8 0.0 6.5e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KIY51281.1 - 1.3e-37 129.4 0.0 2.2e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KIY51281.1 - 8.4e-34 116.7 0.0 1.7e-33 115.7 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 TPR_1 PF00515.28 KIY51282.1 - 3e-08 33.1 10.8 0.034 14.0 1.4 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY51282.1 - 2e-06 27.4 13.6 8.4e-05 22.2 1.0 4.6 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 KIY51282.1 - 2.1e-06 27.4 20.1 0.0073 16.3 1.4 6.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY51282.1 - 0.00011 22.1 0.8 4.4 7.8 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY51282.1 - 0.00073 19.7 1.0 0.7 10.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat zf_Hakai PF18408.1 KIY51283.1 - 0.012 15.3 0.8 0.017 14.8 0.8 1.2 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain zf-C2H2_8 PF15909.5 KIY51283.1 - 0.03 14.6 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KIY51283.1 - 0.11 13.4 1.1 0.17 12.8 1.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger adh_short_C2 PF13561.6 KIY51284.1 - 1.6e-54 185.0 2.6 2.2e-54 184.5 2.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51284.1 - 3.3e-46 157.2 2.3 4.1e-46 156.9 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51284.1 - 2.1e-13 50.6 2.2 2.8e-13 50.2 2.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY51284.1 - 0.00016 21.3 1.3 0.00066 19.2 1.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KIY51284.1 - 0.00052 20.0 0.2 0.0086 16.1 0.2 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Cofilin_ADF PF00241.20 KIY51284.1 - 0.0058 16.4 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1776 PF08643.10 KIY51284.1 - 0.039 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) EpmC PF04315.12 KIY51284.1 - 0.089 12.5 0.4 0.68 9.6 0.1 2.0 1 1 1 2 2 2 0 Elongation factor P hydroxylase THF_DHG_CYH_C PF02882.19 KIY51284.1 - 0.11 11.8 0.1 0.27 10.5 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDC-P PF02347.16 KIY51285.1 - 9.2e-184 611.2 0.0 3.2e-172 573.2 0.0 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KIY51285.1 - 8.2e-05 21.7 0.0 0.0034 16.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIY51285.1 - 0.0019 17.5 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase PPR_2 PF13041.6 KIY51286.1 - 7.9e-16 58.0 0.0 0.024 14.8 0.0 5.9 6 0 0 6 6 6 4 PPR repeat family PPR PF01535.20 KIY51286.1 - 7.7e-10 38.3 2.7 0.012 15.8 0.0 6.6 8 0 0 8 8 8 2 PPR repeat PPR_long PF17177.4 KIY51286.1 - 1.2e-07 31.3 0.0 0.0013 18.2 0.0 3.3 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KIY51286.1 - 4.7e-07 29.8 0.0 0.88 9.7 0.0 4.8 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIY51286.1 - 0.00025 20.7 0.4 0.091 12.5 0.1 4.5 5 0 0 5 5 5 1 PPR repeat TPR_2 PF07719.17 KIY51286.1 - 0.01 15.9 0.0 24 5.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KIY51286.1 - 0.019 15.4 0.1 10 6.5 0.0 3.3 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_1 PF00515.28 KIY51286.1 - 0.025 14.4 0.0 15 5.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 KIY51286.1 - 0.099 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat SecE PF00584.20 KIY51287.1 - 3.4e-14 52.5 0.0 3.9e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex PetG PF02529.15 KIY51288.1 - 3.8 7.4 6.2 3 7.8 0.8 2.5 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 Adeno_E3_14_5 PF04834.12 KIY51288.1 - 3.9 8.1 7.6 3.2 8.3 4.1 2.5 1 1 1 2 2 2 0 Early E3 14.5 kDa protein Vps51 PF08700.11 KIY51289.1 - 1.5e-10 41.0 0.0 5.3e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 DUF3510 PF12022.8 KIY51289.1 - 0.019 15.4 0.2 5.7 7.4 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Halogen_Hydrol PF10112.9 KIY51289.1 - 0.037 14.0 0.2 0.099 12.7 0.2 1.7 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF1751 PF08551.10 KIY51290.1 - 1.2e-22 80.3 5.0 2.4e-22 79.3 5.0 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KIY51290.1 - 0.014 15.4 6.3 0.051 13.6 6.3 1.9 1 1 0 1 1 1 0 Rhomboid family DUF1754 PF08555.10 KIY51291.1 - 4.1e-16 59.6 8.3 5.6e-16 59.1 8.3 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) PHM7_cyt PF14703.6 KIY51292.1 - 0.18 12.0 2.4 0.32 11.2 2.4 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Peptidase_M3 PF01432.20 KIY51293.1 - 3.4e-127 425.5 0.0 4.4e-127 425.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KIY51293.1 - 0.09 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Effector protein Homeodomain PF00046.29 KIY51294.1 - 1.9e-12 46.8 1.0 1.9e-12 46.8 1.0 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KIY51294.1 - 1.1e-06 28.4 0.8 2.5e-06 27.3 0.8 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KIY51294.1 - 0.00092 18.6 0.3 0.0034 16.8 0.0 2.1 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez APC_r PF05923.12 KIY51294.1 - 0.014 15.1 0.6 0.014 15.1 0.6 2.7 2 0 0 2 2 2 0 APC repeat Homeobox_KN PF05920.11 KIY51295.1 - 6.4e-10 38.8 1.7 6.8e-10 38.7 0.2 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KIY51295.1 - 0.00058 19.7 0.0 0.0047 16.7 0.0 2.3 2 0 0 2 2 2 1 Homeodomain Mating_N PF12731.7 KIY51295.1 - 0.0011 19.0 0.2 0.0034 17.4 0.2 1.8 1 0 0 1 1 1 1 Mating-type protein beta 1 zf-C2H2 PF00096.26 KIY51296.1 - 6.8e-18 64.0 24.2 0.0011 19.3 0.6 6.0 5 1 1 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY51296.1 - 1.2e-17 63.1 21.6 0.008 16.9 0.4 5.8 6 0 0 6 6 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY51296.1 - 6.8e-17 61.3 11.9 2.9e-05 24.2 0.4 5.2 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY51296.1 - 8.1e-15 54.7 13.4 0.00041 20.6 0.4 4.8 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KIY51296.1 - 4.1e-10 39.9 11.1 0.017 15.5 0.4 4.6 2 2 2 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KIY51296.1 - 2.3e-07 30.6 17.2 0.0024 17.7 0.9 5.4 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KIY51296.1 - 1.7e-06 27.9 19.8 4.7e-05 23.3 0.5 5.4 5 0 0 5 5 5 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY51296.1 - 1.8e-06 28.1 24.7 0.018 15.4 0.3 5.3 5 0 0 5 5 4 3 Zinc-finger double domain Rad50_zn_hook PF04423.14 KIY51296.1 - 4.2e-06 26.5 4.4 0.44 10.4 0.1 4.4 4 0 0 4 4 4 1 Rad50 zinc hook motif zf-C2HE PF16278.5 KIY51296.1 - 0.00029 21.2 12.4 0.26 11.8 0.4 4.2 3 1 1 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 KIY51296.1 - 0.0025 18.5 6.5 0.093 13.4 0.4 3.0 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats LIM PF00412.22 KIY51296.1 - 0.0038 17.4 13.5 0.29 11.4 1.7 4.1 3 1 0 4 4 4 1 LIM domain zf-C2H2_9 PF16293.5 KIY51296.1 - 0.0042 16.9 9.4 2.3 8.2 0.0 4.4 3 2 2 5 5 5 2 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 KIY51296.1 - 0.0044 17.3 8.9 0.081 13.2 0.2 3.0 2 1 1 3 3 3 1 C2H2-type zinc ribbon zf-CHY PF05495.12 KIY51296.1 - 0.039 14.4 0.7 0.039 14.4 0.7 3.8 2 1 2 4 4 4 0 CHY zinc finger zf-C2H2_11 PF16622.5 KIY51296.1 - 0.061 13.1 12.6 1.6 8.6 0.1 4.8 5 0 0 5 5 5 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 KIY51296.1 - 0.066 13.7 7.5 1.9 9.0 0.4 4.3 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_5 PF13719.6 KIY51296.1 - 0.085 12.6 0.2 0.085 12.6 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 KIY51296.1 - 0.14 12.2 11.9 0.92 9.6 0.5 3.3 2 1 0 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 KIY51296.1 - 0.17 12.2 0.1 0.17 12.2 0.1 4.3 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-DBF PF07535.12 KIY51296.1 - 0.17 12.0 12.4 2.1 8.5 1.0 4.5 3 2 2 5 5 4 0 DBF zinc finger Vps39_2 PF10367.9 KIY51296.1 - 0.2 12.1 10.0 0.94 10.0 0.1 3.8 1 1 3 4 4 4 0 Vacuolar sorting protein 39 domain 2 Zn-ribbon_8 PF09723.10 KIY51296.1 - 0.22 11.7 0.4 0.087 13.0 3.0 4.1 2 2 3 5 5 5 0 Zinc ribbon domain zf-RING_7 PF02591.15 KIY51296.1 - 0.28 11.4 2.1 9.6 6.5 0.0 2.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-TFIIB PF13453.6 KIY51296.1 - 0.34 10.3 8.0 0.91 8.9 0.2 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger Trm112p PF03966.16 KIY51296.1 - 0.39 11.3 3.3 1.1 9.9 0.1 2.9 2 1 0 2 2 2 0 Trm112p-like protein DUF2256 PF10013.9 KIY51296.1 - 0.49 10.5 12.3 27 5.0 0.1 4.9 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) CpXC PF14353.6 KIY51296.1 - 0.58 10.2 0.1 0.58 10.2 0.1 3.2 2 1 0 3 3 2 0 CpXC protein HypA PF01155.19 KIY51296.1 - 0.69 9.9 10.0 0.46 10.5 1.2 3.0 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sgf11 PF08209.11 KIY51296.1 - 0.7 9.5 0.0 0.7 9.5 0.0 4.6 5 0 0 5 5 4 0 Sgf11 (transcriptional regulation protein) CCDC84 PF14968.6 KIY51296.1 - 0.95 9.0 6.8 5.9 6.4 1.1 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 Prok-RING_1 PF14446.6 KIY51296.1 - 1.2 9.1 15.6 9.6 6.2 0.2 5.4 5 1 1 6 6 6 0 Prokaryotic RING finger family 1 CxC7 PF18866.1 KIY51296.1 - 1.6 9.0 5.8 13 6.0 0.0 3.5 4 0 0 4 4 3 0 CxC7 like cysteine cluster associated with KDZ transposases zf_UBZ PF18439.1 KIY51296.1 - 2.3 7.9 9.9 2.1 8.0 0.1 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 KIY51296.1 - 2.6 8.2 17.9 18 5.5 0.2 4.2 3 1 0 3 3 3 0 FYVE zinc finger zinc_ribbon_4 PF13717.6 KIY51296.1 - 8.9 6.3 16.1 25 4.9 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain Actin_micro PF17003.5 KIY51296.1 - 9.7 5.2 7.5 4.7 6.3 0.2 2.9 2 2 1 3 3 3 0 Putative actin-like family zf-C2H2 PF00096.26 KIY51298.1 - 4.1e-11 42.7 7.7 0.00099 19.4 0.6 4.5 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY51298.1 - 3e-09 37.0 9.4 0.007 17.1 0.4 4.1 3 1 1 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY51298.1 - 3.5e-08 33.5 5.1 0.0033 17.7 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY51298.1 - 9.3e-06 25.9 5.7 0.00036 20.8 0.4 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIY51298.1 - 5e-05 23.2 9.7 9.4e-05 22.3 0.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIY51298.1 - 9.4e-05 22.7 7.4 0.021 15.2 0.9 3.3 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.14 KIY51298.1 - 0.0018 18.1 5.5 0.92 9.4 0.2 3.4 3 0 0 3 3 3 2 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 KIY51298.1 - 0.0046 16.8 9.9 0.048 13.6 0.6 3.6 4 0 0 4 4 4 1 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KIY51298.1 - 0.014 15.8 13.1 0.15 12.5 0.8 3.0 3 0 0 3 3 2 0 Zinc-finger double domain zf-CHY PF05495.12 KIY51298.1 - 0.024 15.1 3.3 0.024 15.1 3.3 3.0 3 0 0 3 3 3 0 CHY zinc finger zf-C2HE PF16278.5 KIY51298.1 - 0.03 14.8 5.6 1.4 9.5 0.4 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 KIY51298.1 - 0.12 12.2 3.9 2.8 7.8 0.0 3.0 2 2 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_5 PF13719.6 KIY51298.1 - 0.17 11.7 2.3 0.19 11.5 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KIY51298.1 - 0.19 11.9 7.6 0.092 12.9 3.3 2.6 2 1 1 3 3 3 0 Zinc ribbon domain zf-Di19 PF05605.12 KIY51298.1 - 0.21 11.9 0.3 0.21 11.9 0.3 3.3 2 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF2256 PF10013.9 KIY51298.1 - 0.28 11.3 6.2 4.2 7.6 0.2 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_9 PF14369.6 KIY51298.1 - 0.57 10.5 8.6 21 5.5 3.7 3.7 2 1 0 2 2 2 0 zinc-ribbon C1_4 PF07975.12 KIY51298.1 - 0.85 9.9 6.9 1.4 9.2 2.1 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain RFX_DNA_binding PF02257.15 KIY51299.1 - 0.17 12.6 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain F-box-like PF12937.7 KIY51300.1 - 8.2e-06 25.6 0.7 1.9e-05 24.5 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY51300.1 - 0.0013 18.6 1.0 0.0033 17.3 1.0 1.8 1 0 0 1 1 1 1 F-box domain SBE2 PF17076.5 KIY51301.1 - 0.96 7.6 3.8 0.16 10.1 0.2 1.5 2 0 0 2 2 2 0 SBE2, cell-wall formation Aldo_ket_red PF00248.21 KIY51302.1 - 6.3e-39 133.9 0.0 1.3e-38 132.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family ApbA_C PF08546.11 KIY51303.1 - 6.8e-19 68.3 0.1 1.2e-18 67.5 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KIY51303.1 - 3.1e-13 49.7 0.0 1.7e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Syja_N PF02383.18 KIY51304.1 - 3.6e-84 282.8 0.0 4.9e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain LRR_9 PF14580.6 KIY51305.1 - 1.2e-60 203.9 0.3 1.9e-60 203.4 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KIY51305.1 - 2.3e-09 37.4 12.3 1.8e-06 28.2 3.7 3.6 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY51305.1 - 2.3e-08 33.7 2.0 5.8e-08 32.4 0.8 2.1 2 0 0 2 2 2 1 Leucine rich repeat DUF1707 PF08044.11 KIY51305.1 - 0.1 12.7 0.2 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Pkinase PF00069.25 KIY51306.1 - 1.6e-65 221.1 0.0 3.2e-65 220.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51306.1 - 3.4e-36 124.9 0.0 7.2e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY51306.1 - 1.2e-05 24.9 0.0 3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY51306.1 - 4.6e-05 22.4 0.0 0.0001 21.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY51306.1 - 0.03 14.3 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KIY51306.1 - 0.041 13.5 0.5 0.085 12.5 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KIY51306.1 - 0.077 12.0 0.0 0.27 10.2 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 RRM_1 PF00076.22 KIY51307.1 - 1.8e-32 111.0 0.1 1.3e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY51307.1 - 9.6e-12 44.9 0.2 7.4e-07 29.2 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KIY51307.1 - 0.00081 19.4 0.0 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif OB_RNB PF08206.11 KIY51307.1 - 0.019 14.7 0.2 3.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KIY51307.1 - 0.028 14.4 0.2 2.8 8.0 0.0 2.8 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif UDPGP PF01704.18 KIY51308.1 - 4.7e-47 160.6 0.0 5.6e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KIY51308.1 - 0.034 14.5 0.1 0.074 13.4 0.1 1.7 1 1 0 1 1 1 0 MobA-like NTP transferase domain Taxilin PF09728.9 KIY51309.1 - 4.7e-15 55.6 36.3 1.4e-09 37.6 19.3 2.7 2 1 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 KIY51309.1 - 6.2e-06 25.9 0.4 0.0039 17.0 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIY51309.1 - 0.00035 20.3 0.3 0.025 14.3 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin family PriA_C PF18074.1 KIY51309.1 - 0.17 12.7 1.1 1.3 9.9 0.1 2.9 2 1 1 3 3 3 0 Primosomal protein N C-terminal domain DUF1664 PF07889.12 KIY51309.1 - 1.4 9.0 6.7 2.9 8.0 6.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SAS4 PF15460.6 KIY51310.1 - 1.3e-06 28.4 3.2 3e-06 27.2 3.2 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 KIY51310.1 - 0.00075 20.1 1.3 0.00075 20.1 1.3 3.9 3 1 1 5 5 5 1 PEHE domain Gar1 PF04410.14 KIY51311.1 - 1.6e-33 115.6 1.9 3.2e-33 114.7 0.0 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region RhoGAP PF00620.27 KIY51312.1 - 4e-40 137.1 0.1 6.2e-39 133.3 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KIY51312.1 - 0.22 11.8 1.8 1.1 9.6 0.1 3.0 3 1 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2205 PF10224.9 KIY51312.1 - 0.28 11.2 2.1 11 6.1 0.1 3.6 4 1 0 4 4 4 0 Short coiled-coil protein CENP-K PF11802.8 KIY51313.1 - 0.017 14.7 0.4 0.028 14.0 0.4 1.2 1 0 0 1 1 1 0 Centromere-associated protein K PRKG1_interact PF15898.5 KIY51313.1 - 0.041 14.8 1.5 0.041 14.8 1.5 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CorA PF01544.18 KIY51313.1 - 0.22 10.8 3.1 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MCM PF00493.23 KIY51314.1 - 2.2e-104 347.4 0.1 1.9e-103 344.4 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KIY51314.1 - 1.7e-34 118.4 0.0 3.9e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY51314.1 - 4.2e-30 104.0 0.7 9.5e-30 102.9 0.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIY51314.1 - 1.2e-14 54.8 0.0 3e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIY51314.1 - 8.1e-07 28.6 0.0 0.00026 20.5 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIY51314.1 - 9.2e-05 22.5 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIY51314.1 - 0.00062 19.6 0.1 0.0031 17.4 0.1 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KIY51314.1 - 0.016 15.8 0.6 0.24 12.1 0.1 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 KIY51314.1 - 0.12 12.8 0.0 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) p450 PF00067.22 KIY51315.1 - 1.5e-77 261.4 0.0 1.9e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY51316.1 - 1.3e-66 225.2 0.0 1.7e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIY51317.1 - 2.7e-40 135.6 14.4 2.3e-07 31.4 0.4 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY51317.1 - 1.8e-17 63.4 0.1 0.0074 16.6 0.0 6.8 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KIY51317.1 - 3.4e-13 48.9 1.0 6.4e-13 48.0 1.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 KIY51317.1 - 4.8e-05 22.8 0.0 0.08 12.3 0.0 3.2 4 0 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KIY51317.1 - 0.0031 16.5 0.0 40 3.0 0.0 4.5 2 1 4 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIY51317.1 - 0.042 13.2 0.1 7.5 5.8 0.0 3.4 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIY51317.1 - 3.2 6.3 4.7 22 3.5 0.1 3.3 2 1 2 4 4 4 0 Nucleoporin Nup120/160 bZIP_2 PF07716.15 KIY51318.1 - 1.9e-07 31.0 11.9 1.9e-07 31.0 11.9 3.0 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 KIY51318.1 - 4.9e-05 23.3 8.4 4.9e-05 23.3 8.4 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KIY51318.1 - 7.2 7.2 12.8 0.82 10.2 4.5 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor NPL4 PF05021.15 KIY51319.1 - 6.9e-101 337.6 0.0 9.8e-101 337.1 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KIY51319.1 - 3.8e-62 208.7 0.0 6.2e-62 208.0 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KIY51319.1 - 1.1e-06 29.0 0.0 2.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 WD40 PF00400.32 KIY51320.1 - 1.5e-12 47.8 12.4 0.14 13.1 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat PD40 PF07676.12 KIY51320.1 - 0.62 10.1 2.4 2.5 8.2 0.1 3.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 KIY51321.1 - 2.2e-14 53.0 0.1 3.5e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KIY51321.1 - 1.6e-06 27.9 1.7 2.7e-06 27.2 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIY51321.1 - 0.00065 19.3 1.9 0.00094 18.8 0.7 1.9 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KIY51321.1 - 0.0027 17.6 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIY51321.1 - 0.0067 16.2 0.2 0.018 14.8 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KIY51321.1 - 0.02 14.6 0.2 0.031 14.0 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle FtsX PF02687.21 KIY51322.1 - 0.25 11.8 0.1 0.25 11.8 0.1 2.6 3 0 0 3 3 3 0 FtsX-like permease family Bromodomain PF00439.25 KIY51323.1 - 1.9e-36 124.0 4.6 5.5e-18 64.8 0.9 2.4 2 0 0 2 2 2 2 Bromodomain AT_hook PF02178.19 KIY51323.1 - 4.2 7.6 6.8 0.22 11.5 0.6 2.3 2 0 0 2 2 2 0 AT hook motif Pkinase PF00069.25 KIY51324.1 - 6.3e-43 147.0 0.0 2e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51324.1 - 9.7e-13 48.0 0.0 6e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY51324.1 - 0.016 14.0 1.1 0.038 12.8 0.8 1.6 1 1 1 2 2 2 0 Fungal protein kinase PRELI PF04707.14 KIY51325.1 - 1.2e-35 122.6 0.0 1.4e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Phage_T4_Ndd PF06591.11 KIY51325.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) RIC1 PF07064.13 KIY51327.1 - 2.2e-94 315.6 1.3 3.2e-94 315.0 1.3 1.2 1 0 0 1 1 1 1 RIC1 PD40 PF07676.12 KIY51327.1 - 0.033 14.1 1.2 1.4 8.9 0.4 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.6 KIY51327.1 - 0.045 14.1 0.6 2.8 8.4 0.0 3.6 3 0 0 3 3 3 0 Kelch motif ANAPC4_WD40 PF12894.7 KIY51327.1 - 0.11 12.7 0.0 2 8.8 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_28 PF03033.20 KIY51328.1 - 2.2e-28 99.1 0.0 4e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KIY51328.1 - 4e-21 75.0 1.7 2.5e-12 46.7 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 KIY51328.1 - 9.1e-13 48.6 0.3 2.9e-12 47.0 0.3 2.0 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 KIY51328.1 - 3.2e-07 29.5 0.0 5.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 KIY51328.1 - 0.00032 21.1 1.5 0.058 13.8 1.5 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KIY51328.1 - 0.0059 16.9 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KIY51328.1 - 0.0069 16.5 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 PH domain SUR7 PF06687.12 KIY51329.1 - 6.2e-19 68.5 7.2 7.8e-19 68.1 7.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF5090 PF17009.5 KIY51329.1 - 0.62 10.0 6.2 1.5 8.8 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF2981 PF11200.8 KIY51329.1 - 1 9.1 2.3 1.5 8.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SGT1 PF07093.11 KIY51330.1 - 6.7e-98 328.6 5.7 1.2e-96 324.5 5.3 2.6 1 1 0 1 1 1 1 SGT1 protein Clat_adaptor_s PF01217.20 KIY51331.1 - 6.6e-45 152.5 0.7 1.3e-44 151.6 0.7 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain RDV-p3 PF09231.10 KIY51331.1 - 0.022 12.5 0.1 0.029 12.1 0.1 1.0 1 0 0 1 1 1 0 Rice dwarf virus p3 Med6 PF04934.14 KIY51332.1 - 3.9e-40 136.7 0.0 6.5e-40 136.0 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component zf-C2H2 PF00096.26 KIY51333.1 - 1.1e-08 35.0 18.6 7.9e-07 29.2 0.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY51333.1 - 1e-07 32.2 13.7 0.00014 22.4 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY51333.1 - 7.8e-06 26.1 5.1 0.0048 17.3 1.6 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIY51333.1 - 0.00076 19.4 0.1 0.00076 19.4 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY51333.1 - 0.0012 19.0 1.1 0.02 15.2 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KIY51333.1 - 0.031 15.0 0.6 0.72 10.5 0.5 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 KIY51333.1 - 0.12 12.5 6.1 2 8.6 0.1 2.8 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 KIY51333.1 - 0.31 10.8 5.6 17 5.3 2.9 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-Di19 PF05605.12 KIY51333.1 - 0.32 11.3 3.1 1.6 9.1 2.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TIM21 PF08294.11 KIY51334.1 - 6.2e-21 74.8 0.0 8.1e-20 71.2 0.0 2.1 2 0 0 2 2 2 1 TIM21 DUF5099 PF17025.5 KIY51334.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) Chalcone_2 PF16035.5 KIY51335.1 - 6.9e-26 91.3 0.1 1.2e-14 54.6 0.0 2.3 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 KIY51335.1 - 0.044 13.9 0.1 0.084 13.0 0.1 1.7 1 1 0 1 1 1 0 Chalcone isomerase-like BLM10_mid PF16507.5 KIY51336.1 - 5e-173 576.5 0.0 2.6e-172 574.2 0.0 2.2 3 0 0 3 3 3 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KIY51336.1 - 3.4e-30 103.8 0.2 3.6e-29 100.5 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KIY51336.1 - 3.8e-06 26.7 0.8 0.0011 19.1 0.1 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KIY51336.1 - 0.00011 22.5 0.0 0.023 15.1 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats BLM10_N PF16547.5 KIY51336.1 - 0.00062 20.0 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal Vac14_Fab1_bd PF12755.7 KIY51336.1 - 0.09 13.4 0.9 1.7 9.3 0.1 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KIY51336.1 - 0.12 11.9 0.0 0.41 10.2 0.0 1.9 1 0 0 1 1 1 0 CLASP N terminal Cnd1 PF12717.7 KIY51336.1 - 0.12 12.4 0.1 2.3 8.3 0.1 2.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 zf-CCCH PF00642.24 KIY51337.1 - 2.3e-21 75.2 15.5 2.5e-12 46.4 3.5 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY51337.1 - 1.5e-10 40.8 14.7 1.2e-06 28.4 4.7 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KIY51337.1 - 3.4e-09 36.3 15.4 1.2e-05 25.0 1.6 2.7 2 1 1 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KIY51337.1 - 0.0077 16.9 10.9 0.13 13.0 2.0 2.0 1 1 1 2 2 2 2 Torus domain Defensin_int PF17858.1 KIY51337.1 - 0.058 13.4 3.3 0.13 12.3 0.9 2.1 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide zf-CCCH_2 PF14608.6 KIY51337.1 - 0.068 13.7 0.3 0.068 13.7 0.3 3.1 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCHH PF10283.9 KIY51337.1 - 7.7 6.6 14.8 1.6 8.8 2.2 2.9 3 0 0 3 3 3 0 PBZ domain oligo_HPY PF08352.12 KIY51337.1 - 8.1 7.1 9.3 6.1 7.4 1.6 2.1 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Choline_kinase PF01633.20 KIY51338.1 - 3.5e-51 173.8 0.0 5.3e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KIY51338.1 - 1.3e-08 35.1 0.1 2.1e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.16 KIY51339.1 - 1.1e-27 97.0 39.8 2.8e-26 92.3 39.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY51339.1 - 3.3e-09 36.1 8.5 3.3e-09 36.1 8.5 3.0 2 2 0 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 KIY51339.1 - 0.0024 18.2 1.2 0.0024 18.2 1.2 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3522) YwcE PF17368.2 KIY51339.1 - 1.4 9.6 5.8 29 5.4 3.9 2.8 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE DnaJ_C PF01556.18 KIY51340.1 - 2.6e-36 125.0 0.0 3.3e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY51340.1 - 5.3e-22 77.7 3.0 8.1e-22 77.1 3.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIY51340.1 - 5.1e-09 36.4 20.3 9.5e-09 35.5 19.5 2.0 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 KIY51340.1 - 3 7.9 16.7 4.2 7.4 4.1 3.3 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KIY51340.1 - 3.7 7.6 10.1 3.9 7.5 1.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pkinase PF00069.25 KIY51342.1 - 2.3e-63 214.0 0.1 2.8e-63 213.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51342.1 - 1.1e-19 70.8 0.0 1.6e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY51342.1 - 2.1e-07 31.1 0.8 2.5e-05 24.3 0.2 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY51342.1 - 0.0056 15.5 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY51342.1 - 0.025 13.9 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KIY51342.1 - 0.027 14.1 0.2 0.051 13.2 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-RING_2 PF13639.6 KIY51344.1 - 1.8e-05 25.0 5.2 2.5e-05 24.5 5.2 1.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIY51344.1 - 2.8e-05 23.9 2.0 4.8e-05 23.1 2.0 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIY51344.1 - 3.7e-05 23.7 3.4 0.00041 20.3 0.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY51344.1 - 4.9e-05 23.1 1.8 7.7e-05 22.5 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY51344.1 - 0.00043 20.1 2.5 0.0007 19.4 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY51344.1 - 0.0019 18.0 7.6 0.014 15.2 7.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY51344.1 - 0.0065 16.4 4.6 0.023 14.6 4.9 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIY51344.1 - 0.043 14.0 5.6 0.15 12.3 5.8 1.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KIY51344.1 - 0.078 12.8 2.5 0.13 12.1 2.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KIY51344.1 - 0.12 12.6 4.9 0.2 12.0 4.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF4379 PF14311.6 KIY51344.1 - 4 7.9 8.7 1.1 9.7 4.2 2.1 2 0 0 2 2 2 0 Probable Zinc-ribbon domain UPF0547 PF10571.9 KIY51344.1 - 5.1 7.3 10.5 2.1 8.5 1.3 3.1 2 1 1 3 3 3 0 Uncharacterised protein family UPF0547 UPF0121 PF03661.13 KIY51345.1 - 1.3e-43 149.2 4.6 1.4e-43 149.0 4.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Ribosomal_S27e PF01667.17 KIY51346.1 - 2.6e-29 100.7 4.7 3.2e-29 100.4 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zinc_ribbon_4 PF13717.6 KIY51346.1 - 0.12 12.4 1.8 2.2 8.3 1.8 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Complex1_30kDa PF00329.19 KIY51347.1 - 1.3e-46 158.2 0.0 1.8e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Tim17 PF02466.19 KIY51348.1 - 1.6e-11 44.5 0.5 2.7e-11 43.8 0.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family YhfH PF14149.6 KIY51349.1 - 0.33 11.0 0.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 YhfH-like protein Ras PF00071.22 KIY51350.1 - 1.2e-48 164.8 0.1 1.4e-48 164.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY51350.1 - 2.6e-16 59.9 0.0 4.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIY51350.1 - 0.00023 20.8 0.0 0.0013 18.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY51350.1 - 0.0017 18.3 0.0 0.087 12.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KIY51350.1 - 0.0074 15.8 0.2 0.53 9.8 0.0 2.8 1 1 2 3 3 3 1 Ferrous iron transport protein B AAA_25 PF13481.6 KIY51350.1 - 0.05 13.2 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DOT1 PF08123.13 KIY51350.1 - 0.082 12.4 0.1 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 Histone methylation protein DOT1 AAA_16 PF13191.6 KIY51350.1 - 0.17 12.3 0.7 0.69 10.3 0.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain DUF1299 PF06975.11 KIY51350.1 - 4 7.6 5.7 24 5.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1299) Proteasome PF00227.26 KIY51352.1 - 7.7e-44 149.5 0.1 3.4e-43 147.4 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY51352.1 - 1.1e-14 53.7 0.3 2.1e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ResIII PF04851.15 KIY51352.1 - 0.026 14.5 0.3 0.06 13.3 0.2 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_pol_Rpb1_1 PF04997.12 KIY51353.1 - 3.2e-87 292.8 0.0 5.4e-87 292.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KIY51353.1 - 1.6e-81 273.7 0.3 2.3e-81 273.1 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIY51353.1 - 5.2e-72 241.5 0.0 1.6e-71 239.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KIY51353.1 - 2.4e-37 128.3 0.0 2.8e-36 124.8 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KIY51353.1 - 4.2e-31 107.1 0.0 1.2e-30 105.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF2786 PF10979.8 KIY51353.1 - 0.031 14.2 0.1 0.075 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) SLS PF14611.6 KIY51353.1 - 0.051 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DUF2703 PF10865.8 KIY51353.1 - 0.11 12.6 0.0 0.65 10.2 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) zf-RING_7 PF02591.15 KIY51353.1 - 0.12 12.6 2.3 1.1 9.5 0.1 3.2 3 0 0 3 3 3 0 C4-type zinc ribbon domain Yippee-Mis18 PF03226.14 KIY51355.1 - 1.1e-15 57.7 0.6 1.3e-15 57.5 0.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KIY51355.1 - 0.0068 16.6 1.0 0.0098 16.1 1.0 1.3 1 1 0 1 1 1 1 C-terminal domain of RIG-I DUF1664 PF07889.12 KIY51356.1 - 0.98 9.5 3.7 1.8 8.6 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tho2 PF11262.8 KIY51356.1 - 9.4 5.3 10.0 21 4.2 10.0 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF900 PF05990.12 KIY51357.1 - 0.0043 16.6 0.0 0.006 16.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Transposase_21 PF02992.14 KIY51357.1 - 0.075 12.3 0.1 0.92 8.7 0.0 2.2 2 0 0 2 2 2 0 Transposase family tnp2 DUF4218 PF13960.6 KIY51358.1 - 1.6e-06 27.7 0.1 6.2e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Kelch_5 PF13854.6 KIY51359.1 - 7.2e-33 112.1 4.1 2e-10 40.4 0.7 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KIY51359.1 - 4.3e-30 103.0 8.1 2.3e-08 34.0 0.1 4.1 3 1 1 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KIY51359.1 - 4.5e-28 97.0 8.8 1.4e-06 28.2 0.0 4.1 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KIY51359.1 - 4.6e-26 90.2 7.6 1.6e-06 27.6 0.0 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KIY51359.1 - 2.1e-22 78.9 8.4 2.3e-07 31.0 0.2 4.2 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KIY51359.1 - 2.2e-22 78.1 4.6 6e-06 26.0 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Goodbye PF17109.5 KIY51361.1 - 0.0041 17.5 0.0 0.007 16.8 0.0 1.3 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Hist_deacetyl PF00850.19 KIY51363.1 - 7.9e-84 281.7 0.0 1.1e-83 281.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PTH2 PF01981.16 KIY51364.1 - 3.3e-29 101.5 0.0 3.7e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF5313 PF17240.2 KIY51365.1 - 0.043 14.2 0.6 0.043 14.2 0.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5313) MerC PF03203.14 KIY51365.1 - 0.47 10.9 14.6 0.37 11.3 6.9 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein DUF420 PF04238.12 KIY51365.1 - 0.68 10.2 15.3 0.058 13.7 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF5518 PF17647.1 KIY51365.1 - 8.3 6.6 12.7 0.33 11.1 2.5 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5518) Use1 PF09753.9 KIY51366.1 - 0.039 13.7 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Peptidase_C48 PF02902.19 KIY51367.1 - 4.1e-38 131.4 0.2 2e-37 129.2 0.2 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF5509 PF17625.2 KIY51367.1 - 0.028 13.6 0.5 0.039 13.1 0.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5509) DinB_2 PF12867.7 KIY51368.1 - 9.8e-05 22.9 1.9 0.00013 22.5 1.9 1.2 1 0 0 1 1 1 1 DinB superfamily EpmC PF04315.12 KIY51368.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P hydroxylase ATP-grasp_2 PF08442.10 KIY51369.1 - 1.4e-70 237.0 2.0 2.1e-70 236.4 0.8 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KIY51369.1 - 7.8e-25 87.5 0.2 1.8e-24 86.3 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KIY51369.1 - 1e-09 38.2 0.3 2.2e-09 37.1 0.3 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KIY51369.1 - 0.00011 22.1 0.1 0.00035 20.4 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Inhibitor_I69 PF13734.6 KIY51369.1 - 0.04 14.3 0.7 4.1 7.9 0.0 3.2 3 0 0 3 3 3 0 Spi protease inhibitor HDC PF02329.16 KIY51369.1 - 0.085 11.9 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Histidine carboxylase PI chain DUF1682 PF07946.14 KIY51370.1 - 5.9 6.0 8.0 11 5.1 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF5427 PF10310.9 KIY51371.1 - 1.4e-57 195.8 3.8 2.3e-50 171.9 0.1 2.5 1 1 1 2 2 2 2 Family of unknown function (DUF5427) BCAS2 PF05700.11 KIY51372.1 - 2.2e-66 223.5 11.2 2.4e-66 223.3 11.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.9 KIY51372.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.6 2 0 0 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor LRR_RI_capping PF18779.1 KIY51372.1 - 0.041 13.5 0.3 0.12 12.1 0.3 1.7 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat DUF4404 PF14357.6 KIY51372.1 - 1.3 9.7 6.3 7.2 7.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) BLM10_mid PF16507.5 KIY51373.1 - 2.6e-179 597.2 0.0 4.2e-179 596.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KIY51373.1 - 3.4e-28 97.4 0.0 1.6e-27 95.2 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KIY51373.1 - 0.00032 20.7 7.7 0.32 11.4 0.1 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KIY51373.1 - 0.0016 18.8 1.9 3.5 8.1 0.1 4.2 4 0 0 4 4 4 2 HEAT repeats DcpS_C PF11969.8 KIY51374.1 - 3.7e-07 30.6 0.0 6.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3875 PF12991.7 KIY51374.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3875) BTG PF07742.12 KIY51376.1 - 2.6e-11 43.4 0.0 4.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 BTG family DUF4614 PF15391.6 KIY51376.1 - 0.018 15.0 5.5 0.028 14.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CCDC106 PF15794.5 KIY51376.1 - 0.048 13.4 3.1 0.067 12.9 3.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Miga PF10265.9 KIY51376.1 - 0.43 9.5 3.1 0.54 9.2 3.1 1.1 1 0 0 1 1 1 0 Mitoguardin SR-25 PF10500.9 KIY51376.1 - 1.2 8.6 18.2 2.5 7.7 18.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 KIY51376.1 - 1.7 6.8 7.2 2 6.6 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 KIY51376.1 - 3.5 6.1 6.0 4.2 5.8 6.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF1687 PF07955.11 KIY51377.1 - 9.8e-15 55.2 0.0 1.3e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Rhodanese PF00581.20 KIY51378.1 - 6.8e-09 36.2 0.0 1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain BATS PF06968.13 KIY51379.1 - 1.9e-22 79.2 0.1 7e-22 77.4 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KIY51379.1 - 1.8e-16 61.0 0.1 2.8e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Plasmid_RAQPRD PF09686.10 KIY51379.1 - 0.06 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) GTP_EFTU PF00009.27 KIY51380.1 - 1.7e-50 171.3 0.0 2.5e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIY51380.1 - 2.3e-17 62.8 0.0 5.7e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KIY51380.1 - 1.4e-06 28.3 0.2 2.6e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIY51380.1 - 0.00036 20.8 2.2 0.00057 20.2 0.9 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KIY51380.1 - 0.0044 17.0 0.0 0.17 11.7 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase Septin PF00735.18 KIY51380.1 - 0.014 14.7 0.1 0.063 12.5 0.1 1.8 2 0 0 2 2 2 0 Septin SRPRB PF09439.10 KIY51380.1 - 0.015 14.7 0.1 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KIY51380.1 - 0.033 13.7 0.0 0.21 11.1 0.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.14 KIY51380.1 - 0.053 13.4 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B F_bP_aldolase PF01116.20 KIY51380.1 - 0.094 12.2 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Fructose-bisphosphate aldolase class-II Arf PF00025.21 KIY51380.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family DUF1275 PF06912.11 KIY51381.1 - 2.4e-27 96.1 13.1 3e-27 95.8 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3487 PF11990.8 KIY51381.1 - 0.056 13.3 2.4 0.14 12.0 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) CBS PF00571.28 KIY51382.1 - 1.2e-34 118.5 6.2 3.1e-08 34.0 0.1 4.7 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 KIY51382.1 - 7.5e-09 35.4 0.4 2.2e-08 33.9 0.4 1.8 1 1 0 1 1 1 1 PB1 domain DUF3604 PF12228.8 KIY51382.1 - 0.12 10.8 0.1 0.19 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) Sgf11 PF08209.11 KIY51383.1 - 2.4e-14 52.6 1.1 5e-14 51.6 1.1 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KIY51383.1 - 0.042 13.7 0.4 0.096 12.6 0.4 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KIY51383.1 - 0.14 12.4 3.3 0.71 10.2 0.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF508 PF04370.12 KIY51383.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF508) Retrotrans_gag PF03732.17 KIY51385.1 - 0.00033 20.9 0.5 0.00033 20.9 0.5 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein ANAPC4_WD40 PF12894.7 KIY51389.1 - 8.3e-13 48.5 0.1 0.00038 20.7 0.0 6.7 7 1 1 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY51389.1 - 1.8e-10 41.2 20.9 0.021 15.7 0.0 9.1 10 0 0 10 10 10 4 WD domain, G-beta repeat PD40 PF07676.12 KIY51389.1 - 0.00012 21.9 3.4 5.9 7.0 0.0 4.0 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIY51389.1 - 0.003 16.6 0.7 0.14 11.1 0.0 3.6 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Mpv17_PMP22 PF04117.12 KIY51391.1 - 1.6e-24 85.9 0.4 2.9e-24 85.1 0.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family PTH2 PF01981.16 KIY51392.1 - 1.7e-18 67.0 0.1 1.9e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 zf-Tim10_DDP PF02953.15 KIY51393.1 - 4.4e-17 61.5 1.6 5.8e-17 61.1 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KIY51393.1 - 0.036 13.8 1.5 0.05 13.3 1.5 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) zf-met2 PF12907.7 KIY51394.1 - 8.4e-14 51.4 2.0 1.3e-13 50.8 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KIY51394.1 - 8.1e-06 26.6 8.5 8.1e-06 26.6 8.5 1.6 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_12 PF18658.1 KIY51394.1 - 0.095 12.3 0.4 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type Ripply PF14998.6 KIY51394.1 - 0.1 13.3 0.2 0.14 12.9 0.2 1.1 1 0 0 1 1 1 0 Transcription Regulator Beta_elim_lyase PF01212.21 KIY51395.1 - 6e-72 242.4 0.0 7.9e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KIY51395.1 - 1.1e-06 28.1 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIY51395.1 - 5.7e-05 21.8 0.0 8.9e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIY51395.1 - 0.0072 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIY51395.1 - 0.014 14.7 0.0 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Urb2 PF10441.9 KIY51396.1 - 2.6e-42 145.1 0.4 5.1e-42 144.1 0.0 1.6 2 0 0 2 2 2 1 Urb2/Npa2 family THEG PF14912.6 KIY51396.1 - 0.052 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Testicular haploid expressed repeat Bromodomain PF00439.25 KIY51397.1 - 7.8e-40 134.8 0.2 5.7e-20 71.2 0.0 2.8 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KIY51397.1 - 7.7e-19 67.6 0.2 1.8e-18 66.4 0.2 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 KIY51397.1 - 0.0042 17.0 2.7 0.018 15.0 2.7 2.0 1 0 0 1 1 1 1 FlxA-like protein Hid1 PF12722.7 KIY51397.1 - 0.0055 14.9 2.1 0.0079 14.4 2.1 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein SOGA PF11365.8 KIY51397.1 - 0.035 15.2 1.8 0.099 13.8 1.8 1.7 1 0 0 1 1 1 0 Protein SOGA Not3 PF04065.15 KIY51397.1 - 0.086 12.3 3.1 0.21 11.0 2.2 2.1 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF1664 PF07889.12 KIY51397.1 - 0.097 12.7 0.6 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KIY51397.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.8 3 0 0 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Swi5 PF07061.11 KIY51397.1 - 0.13 12.3 2.2 0.35 11.0 2.2 1.7 1 0 0 1 1 1 0 Swi5 Lin-8 PF03353.15 KIY51397.1 - 0.7 9.4 6.2 1.8 8.1 6.2 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3847 PF12958.7 KIY51397.1 - 1.6 8.9 6.3 4.1 7.6 6.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) ATP11 PF06644.11 KIY51397.1 - 3.1 7.5 7.0 7.3 6.3 7.0 1.6 1 0 0 1 1 1 0 ATP11 protein FAM220 PF15487.6 KIY51397.1 - 3.5 7.2 7.3 7.7 6.1 7.3 1.5 1 0 0 1 1 1 0 FAM220 family MerR-DNA-bind PF09278.11 KIY51397.1 - 4.2 8.0 8.8 0.73 10.4 3.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding WD40 PF00400.32 KIY51398.1 - 1.9e-24 85.5 12.2 6.5e-06 26.8 1.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY51398.1 - 5.1e-08 33.1 0.0 0.41 11.0 0.0 4.9 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY51398.1 - 6.5e-07 29.4 0.1 0.0029 17.5 0.0 3.3 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIY51398.1 - 3.7e-06 26.1 0.1 9.3e-05 21.5 0.0 2.6 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIY51398.1 - 4.8e-05 23.2 0.0 5.9 7.0 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat PWI PF01480.17 KIY51399.1 - 7.1e-09 35.9 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KIY51399.1 - 6.1e-07 29.2 4.1 1.1e-06 28.4 4.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KIY51399.1 - 9e-06 25.4 0.2 3.8e-05 23.4 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KIY51399.1 - 0.0011 19.6 0.5 0.0033 18.1 0.4 1.8 2 0 0 2 2 1 1 Torus domain zf_CCCH_4 PF18345.1 KIY51399.1 - 0.0012 18.8 6.8 0.0023 17.9 6.8 1.5 1 0 0 1 1 1 1 Zinc finger domain RRM_3 PF08777.11 KIY51399.1 - 0.067 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Snapin_Pallidin PF14712.6 KIY51399.1 - 0.16 12.4 3.5 0.16 12.4 1.4 2.0 2 0 0 2 2 2 0 Snapin/Pallidin zf-CCCH_2 PF14608.6 KIY51399.1 - 0.21 12.1 2.1 0.37 11.3 2.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FapA PF03961.13 KIY51399.1 - 0.31 9.6 3.7 0.46 9.0 3.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-CCCH_4 PF18044.1 KIY51399.1 - 0.83 9.5 5.0 1.5 8.7 5.0 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger PRKG1_interact PF15898.5 KIY51399.1 - 0.87 10.5 9.5 1.8 9.5 9.5 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4726 PF15855.5 KIY51399.1 - 1.5 9.1 5.9 1.6 9.0 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4726) TMF_TATA_bd PF12325.8 KIY51399.1 - 2.1 8.6 9.9 4.1 7.6 9.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 KIY51399.1 - 2.2 8.8 6.8 8.1 7.0 2.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 KIY51399.1 - 3.9 7.6 16.7 5 7.3 8.6 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 KIY51399.1 - 5.5 5.8 8.1 1e+02 1.6 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Rhodanese PF00581.20 KIY51400.1 - 6.5e-17 62.0 0.0 7.5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF442 PF04273.13 KIY51400.1 - 0.062 13.4 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative phosphatase (DUF442) RlmM_FDX PF18125.1 KIY51400.1 - 0.19 12.2 0.0 0.3 11.6 0.0 1.2 1 0 0 1 1 1 0 RlmM ferredoxin-like domain Frataxin_Cyay PF01491.16 KIY51401.1 - 6.4e-39 132.4 0.0 7.1e-39 132.2 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Ctr PF04145.15 KIY51403.1 - 1.2e-29 103.8 0.0 1.6e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family S_2TMBeta PF18153.1 KIY51403.1 - 0.17 11.6 0.2 0.31 10.8 0.2 1.4 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain Megourin PF17560.2 KIY51404.1 - 0.025 14.8 0.1 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 Aphid Megourins Myb_CC_LHEQLE PF14379.6 KIY51405.1 - 0.0022 17.6 0.6 0.66 9.7 0.0 2.5 2 0 0 2 2 2 2 MYB-CC type transfactor, LHEQLE motif Ion_trans_N PF08412.10 KIY51405.1 - 0.073 12.7 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Ion transport protein N-terminal KDZ PF18758.1 KIY51406.1 - 4.6e-40 137.6 0.1 6.7e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Pfg27 PF09216.10 KIY51406.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Pfg27 KDZ PF18758.1 KIY51407.1 - 1.5e-24 86.9 0.3 3e-24 85.9 0.3 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY51407.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases 2OG-FeII_Oxy_3 PF13640.6 KIY51409.1 - 0.033 15.1 0.0 0.051 14.5 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily BMFP PF04380.13 KIY51410.1 - 0.044 14.3 0.4 0.43 11.1 0.0 2.5 2 1 0 2 2 2 0 Membrane fusogenic activity FlaC_arch PF05377.11 KIY51410.1 - 0.11 12.9 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DNA_pol_B_2 PF03175.13 KIY51412.1 - 1.7e-51 175.6 6.4 1.9e-51 175.4 6.4 1.0 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral GHMP_kinases_C PF08544.13 KIY51414.1 - 5.8e-08 33.0 0.1 1.5e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 GHMP kinases C terminal FliG_N PF14842.6 KIY51414.1 - 0.049 14.2 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 FliG N-terminal domain DUF1765 PF08578.10 KIY51415.1 - 0.16 12.4 0.0 0.58 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) RexA PF15969.5 KIY51415.1 - 0.26 10.8 1.0 0.72 9.4 0.1 1.9 2 0 0 2 2 2 0 Intracellular sensor of Lambda phage, Abi component Plavaka PF18759.1 KIY51416.1 - 1.3e-106 356.6 0.0 5.3e-104 347.9 0.0 2.2 1 1 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 KIY51416.1 - 0.012 16.4 1.5 0.046 14.6 1.5 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger NIL PF09383.10 KIY51416.1 - 0.053 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 NIL domain zf-C2H2 PF00096.26 KIY51416.1 - 0.075 13.5 2.1 0.29 11.7 2.1 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type DDE_3 PF13358.6 KIY51420.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease Gal_GalNac_35kD PF17337.2 KIY51420.1 - 0.12 12.4 1.4 0.99 9.4 0.2 2.0 1 1 1 2 2 2 0 Galactose-inhibitable lectin 35 kDa subunit Glyco_hydro_31 PF01055.26 KIY51421.1 - 1.7e-14 53.9 0.0 2.1e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 HMG_box_2 PF09011.10 KIY51423.1 - 0.00074 20.1 0.1 0.0017 18.9 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain DUF1178 PF06676.11 KIY51423.1 - 0.0049 17.3 0.3 0.01 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1178) Hepar_II_III PF07940.13 KIY51423.1 - 0.065 12.9 0.1 0.075 12.6 0.1 1.0 1 0 0 1 1 1 0 Heparinase II/III-like protein Gluconate_2-dh3 PF13618.6 KIY51423.1 - 0.16 12.2 0.6 0.41 10.9 0.1 1.8 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Metal_resist PF13801.6 KIY51423.1 - 0.19 11.9 6.4 2.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Heavy-metal resistance LPD38 PF18857.1 KIY51424.1 - 0.072 13.2 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 38 KDZ PF18758.1 KIY51425.1 - 9.1e-23 81.0 0.0 1.6e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY51425.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY51425.1 - 0.0079 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY51425.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY51426.1 - 4.8e-38 131.0 0.0 7.4e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase HHH_8 PF14716.6 KIY51426.1 - 0.022 15.1 0.3 66 4.0 0.0 3.5 3 1 0 3 3 3 0 Helix-hairpin-helix domain Flavi_NS4A PF01350.17 KIY51426.1 - 0.19 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A SH3BP5 PF05276.14 KIY51426.1 - 0.42 10.4 3.2 0.26 11.0 1.2 1.7 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) p450 PF00067.22 KIY51428.1 - 3.5e-15 55.7 0.0 4.6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KIY51429.1 - 6.7e-66 222.3 0.0 1.3e-65 221.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51429.1 - 6.3e-36 124.0 0.0 1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY51429.1 - 2.6e-10 40.1 0.0 5.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY51429.1 - 1.5e-06 27.3 0.1 2.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY51429.1 - 0.00023 20.6 2.2 0.0003 20.2 0.1 2.2 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY51429.1 - 0.037 13.0 0.2 0.054 12.4 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIY51429.1 - 0.039 13.9 0.3 0.085 12.8 0.3 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIY51429.1 - 0.056 12.5 0.4 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KIY51429.1 - 0.068 12.1 0.8 0.086 11.8 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase KDZ PF18758.1 KIY51430.1 - 2.2e-27 96.1 1.5 2.6e-27 95.9 1.5 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zf-RVT PF13966.6 KIY51434.1 - 5.5e-05 23.8 0.0 7.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Vps36-NZF-N PF16988.5 KIY51435.1 - 0.00019 20.7 0.3 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain OrsD PF12013.8 KIY51435.1 - 0.0004 20.8 0.8 0.0019 18.6 1.0 2.0 1 1 1 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 KIY51435.1 - 0.005 17.6 4.7 1.2 10.2 1.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 KIY51435.1 - 0.015 15.3 1.0 0.11 12.5 0.4 2.2 2 0 0 2 2 2 0 BED zinc finger zf-UBP PF02148.19 KIY51435.1 - 0.043 14.1 0.3 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein PIH1 PF08190.12 KIY51437.1 - 7e-25 87.4 0.0 1.4e-24 86.4 0.0 1.4 2 0 0 2 2 2 1 PIH1 N-terminal domain DUF917 PF06032.12 KIY51439.1 - 1.1e-126 422.4 0.8 1.1e-126 422.4 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KIY51439.1 - 6.9e-28 97.7 10.4 1.5e-25 90.1 0.3 3.3 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIY51439.1 - 5.2e-27 94.7 0.0 2.6e-24 85.9 0.0 2.9 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.11 KIY51439.1 - 0.0002 20.7 0.1 0.045 13.0 0.0 2.4 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.20 KIY51439.1 - 0.00036 20.1 2.4 0.57 9.6 0.0 3.7 4 0 0 4 4 4 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 KIY51439.1 - 0.0064 15.1 0.3 0.052 12.1 0.0 2.2 2 0 0 2 2 2 1 MutL protein F-box-like PF12937.7 KIY51441.1 - 0.00041 20.2 0.1 0.0025 17.7 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY51441.1 - 0.01 15.7 0.1 0.13 12.2 0.1 2.5 2 0 0 2 2 2 0 F-box domain Peptidase_M20 PF01546.28 KIY51443.1 - 1.6e-26 93.3 0.0 2.7e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KIY51443.1 - 3.8e-14 52.8 12.6 7.2e-06 26.6 0.2 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat M20_dimer PF07687.14 KIY51443.1 - 2.4e-10 40.3 0.0 4.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 KIY51443.1 - 0.00015 22.0 0.1 5.4 7.4 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KIY51443.1 - 0.00095 19.0 0.2 0.72 9.9 0.1 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat GIY-YIG PF01541.24 KIY51443.1 - 0.03 14.6 0.0 0.09 13.1 0.0 1.8 2 0 0 2 2 2 0 GIY-YIG catalytic domain PQQ_3 PF13570.6 KIY51443.1 - 0.039 14.5 0.0 0.78 10.3 0.1 3.2 3 0 0 3 3 3 0 PQQ-like domain RVT_1 PF00078.27 KIY51446.1 - 1.1e-06 28.3 0.0 2e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIY51447.1 - 2.3e-08 34.6 0.6 1.7e-07 31.9 0.0 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF5465 PF17553.2 KIY51449.1 - 0.18 12.4 9.4 35 5.3 0.4 5.2 3 1 0 3 3 3 0 Family of unknown function (DUF5465) HsbA PF12296.8 KIY51449.1 - 0.32 11.4 13.1 0.1 13.1 7.4 2.8 1 1 1 3 3 3 0 Hydrophobic surface binding protein A NPV_P10 PF05531.12 KIY51449.1 - 0.75 10.3 7.4 11 6.6 0.2 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Sugar_tr PF00083.24 KIY51451.1 - 4e-26 91.9 18.2 9.6e-16 57.7 7.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIY51451.1 - 5e-14 52.0 38.0 1.7e-13 50.3 36.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 KIY51451.1 - 0.15 12.4 6.4 5.3 7.4 0.9 3.8 2 1 0 2 2 2 0 Transglycosylase associated protein Cwf_Cwc_15 PF04889.12 KIY51452.1 - 2.2 7.9 8.7 3.1 7.4 8.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein F-box-like PF12937.7 KIY51453.1 - 7.4e-07 29.0 0.5 2.5e-06 27.3 0.5 1.9 1 1 0 1 1 1 1 F-box-like Cob_adeno_trans PF01923.18 KIY51453.1 - 0.0099 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase ABC_tran_CTD PF16326.5 KIY51453.1 - 0.076 13.3 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Cpn60_TCP1 PF00118.24 KIY51455.1 - 1.3e-146 489.1 0.6 1.5e-146 488.9 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans PF04082.18 KIY51456.1 - 1.7e-09 37.2 0.7 1.7e-05 24.0 0.3 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Acylphosphatase PF00708.18 KIY51457.1 - 0.042 14.2 0.0 0.063 13.7 0.0 1.2 1 0 0 1 1 1 0 Acylphosphatase Aminotran_5 PF00266.19 KIY51458.1 - 4.5e-23 81.8 0.0 1.7e-22 79.9 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class-V PseudoU_synth_2 PF00849.22 KIY51459.1 - 1.4e-25 90.2 0.0 2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Evr1_Alr PF04777.13 KIY51462.1 - 5.3e-27 94.2 0.4 5.3e-27 94.2 0.4 1.6 2 0 0 2 2 2 1 Erv1 / Alr family APOBEC1 PF18769.1 KIY51462.1 - 0.14 12.4 0.1 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 APOBEC1 Zn_ribbon_SprT PF17283.2 KIY51462.1 - 0.18 11.7 2.0 24 4.9 0.0 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain ABC_tran PF00005.27 KIY51464.1 - 1.2e-24 87.4 0.0 2.2e-14 54.2 0.0 3.3 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KIY51464.1 - 8.4e-10 38.9 1.2 0.0016 18.3 0.2 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KIY51464.1 - 0.00058 20.0 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KIY51464.1 - 0.0011 18.4 0.0 0.76 9.2 0.0 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIY51464.1 - 0.0033 17.1 0.1 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF4096 PF13340.6 KIY51464.1 - 0.026 14.7 0.0 0.61 10.3 0.0 2.6 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) NACHT PF05729.12 KIY51464.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KIY51464.1 - 0.062 12.5 0.0 6.1 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 KIY51464.1 - 0.092 13.1 0.2 0.55 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KIY51464.1 - 0.12 12.9 0.2 0.18 12.3 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY51464.1 - 0.16 12.3 0.5 1.4 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF3584 PF12128.8 KIY51464.1 - 0.3 8.5 0.0 0.42 8.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cwf_Cwc_15 PF04889.12 KIY51465.1 - 1.7e-83 280.2 20.2 1.9e-83 280.0 20.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF1839 PF08893.10 KIY51465.1 - 0.072 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Nop14 PF04147.12 KIY51465.1 - 0.18 10.0 17.0 0.22 9.7 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 KIY51465.1 - 2.9 6.8 13.4 4.3 6.3 13.4 1.2 1 0 0 1 1 1 0 Pes-10 adh_short_C2 PF13561.6 KIY51466.1 - 2e-12 47.2 0.0 6.8e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51466.1 - 2.6e-12 46.6 0.0 1.2e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 KIY51466.1 - 0.016 14.9 1.0 0.034 13.9 1.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.17 KIY51466.1 - 0.023 15.3 0.2 0.05 14.2 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 KIY51467.1 - 6.6e-16 58.6 0.0 1.2e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51467.1 - 4.2e-09 36.2 0.0 7.2e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIY51467.1 - 0.00017 21.6 0.3 0.00027 20.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIY51467.1 - 0.014 15.7 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KIY51467.1 - 0.018 15.6 0.2 0.033 14.8 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.8 KIY51467.1 - 0.02 14.7 1.0 0.04 13.7 1.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-CHY PF05495.12 KIY51468.1 - 1.3e-13 51.2 14.5 2e-13 50.6 14.5 1.3 1 0 0 1 1 1 1 CHY zinc finger zf-FPG_IleRS PF06827.14 KIY51468.1 - 0.0069 16.2 0.6 0.014 15.2 0.6 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 KIY51468.1 - 0.0081 16.3 6.1 0.015 15.4 2.5 2.3 2 0 0 2 2 2 1 Zinc ribbon domain Cys_rich_KTR PF14205.6 KIY51468.1 - 0.015 15.1 7.8 1.3 8.9 3.3 2.4 1 1 1 2 2 2 0 Cysteine-rich KTR DUF3158 PF11358.8 KIY51468.1 - 0.019 14.7 0.2 0.026 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) DUF3909 PF13077.6 KIY51468.1 - 0.027 14.6 0.2 0.047 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) DUF4379 PF14311.6 KIY51468.1 - 0.55 10.6 10.3 0.15 12.5 2.0 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain zf-C2H2_6 PF13912.6 KIY51468.1 - 0.69 10.0 6.1 0.67 10.0 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 KIY51468.1 - 0.87 9.6 10.9 6.7 6.8 0.1 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain LIM PF00412.22 KIY51468.1 - 1 9.6 12.8 2.9 8.2 10.5 2.2 1 1 1 2 2 2 0 LIM domain zinc_ribbon_10 PF10058.9 KIY51468.1 - 8.3 6.2 9.8 1.6 8.5 2.6 2.3 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Y_phosphatase3 PF13350.6 KIY51470.1 - 2.1e-58 198.0 0.0 2.4e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIY51470.1 - 0.0022 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KIY51470.1 - 0.0025 17.4 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KIY51470.1 - 0.079 12.8 0.0 0.21 11.4 0.0 1.9 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 KIY51470.1 - 0.19 10.6 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Bromodomain PF00439.25 KIY51471.1 - 9.5e-23 80.1 0.4 2.2e-22 78.9 0.4 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KIY51471.1 - 1.8e-05 24.6 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Fungal_trans PF04082.18 KIY51472.1 - 1.4e-21 76.7 0.1 2.4e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M75 PF09375.10 KIY51472.1 - 0.0067 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Imelysin GST_C_3 PF14497.6 KIY51476.1 - 3.2e-24 85.0 0.3 6e-24 84.1 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY51476.1 - 1.4e-05 25.0 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY51476.1 - 7.1e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIY51476.1 - 0.11 12.9 0.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Ribonuclease PF00545.20 KIY51477.1 - 4e-05 24.3 0.0 5.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 ribonuclease F-box-like PF12937.7 KIY51478.1 - 0.0068 16.3 0.1 0.026 14.4 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY51479.1 - 2.9e-11 43.1 6.4 2.4e-05 24.1 0.9 3.1 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KIY51479.1 - 0.071 13.0 7.5 5.1 7.1 0.7 4.6 3 1 0 3 3 3 0 F-box domain Glyco_hydro81C PF17652.1 KIY51480.1 - 4e-68 230.2 5.8 6.4e-68 229.6 5.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KIY51480.1 - 5e-30 104.8 3.9 8.5e-30 104.0 3.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain FRG1 PF06229.12 KIY51480.1 - 0.021 14.5 0.2 1.4 8.6 0.0 2.2 1 1 1 2 2 2 0 FRG1-like domain Fascin PF06268.13 KIY51480.1 - 0.073 13.3 0.0 0.31 11.3 0.0 2.0 1 1 0 1 1 1 0 Fascin domain FKBP_C PF00254.28 KIY51481.1 - 2.4e-31 107.9 0.0 2.8e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FlgT_N PF16548.5 KIY51482.1 - 0.13 12.9 5.2 0.17 12.4 3.8 1.8 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain Borrelia_P83 PF05262.11 KIY51482.1 - 0.44 9.0 14.9 0.44 9.0 14.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CSG2 PF16965.5 KIY51482.1 - 0.59 9.0 2.1 0.66 8.9 2.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DDHD PF02862.17 KIY51482.1 - 1.2 9.2 7.5 1.4 9.1 7.5 1.1 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.15 KIY51482.1 - 1.2 7.9 3.2 1.3 7.9 3.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4834 PF16118.5 KIY51482.1 - 1.7 9.7 18.3 21 6.2 18.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) RR_TM4-6 PF06459.12 KIY51482.1 - 1.9 8.2 13.6 2.1 8.1 13.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 KIY51482.1 - 3.2 6.9 7.5 3.3 6.8 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ureide_permease PF07168.11 KIY51482.1 - 3.3 6.4 6.6 4.3 6.0 6.6 1.2 1 0 0 1 1 1 0 Ureide permease Med19 PF10278.9 KIY51482.1 - 5.4 6.9 19.6 7.3 6.5 19.6 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4718 PF15842.5 KIY51482.1 - 6 6.6 10.7 0.11 12.3 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) Zn_clus PF00172.18 KIY51486.1 - 1.3e-05 25.2 4.0 2.2e-05 24.5 4.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPA3 PF07047.12 KIY51488.1 - 1.4e-43 147.6 1.6 2e-43 147.1 1.6 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.9 KIY51488.1 - 0.086 13.3 0.9 0.2 12.1 0.9 1.8 1 1 0 1 1 1 0 Mediator complex protein TraC PF07820.12 KIY51488.1 - 0.15 12.4 0.7 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 TraC-like protein Matrilin_ccoil PF10393.9 KIY51488.1 - 5.3 7.0 5.0 4.2 7.3 0.2 3.0 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin adh_short_C2 PF13561.6 KIY51491.1 - 5.3e-55 186.5 3.6 6.2e-55 186.3 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51491.1 - 1.8e-43 148.3 4.1 2.3e-43 147.9 4.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51491.1 - 3.4e-10 40.1 1.4 4.7e-10 39.7 1.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY51491.1 - 0.0072 15.8 0.5 0.0098 15.4 0.5 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIY51491.1 - 0.019 14.3 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_trans_4_2 PF13477.6 KIY51491.1 - 0.14 12.2 0.0 1 9.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like Flavokinase PF01687.17 KIY51493.1 - 1.3e-30 106.0 0.0 1.5e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase SRX PF09201.10 KIY51494.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit Exo_endo_phos PF03372.23 KIY51495.1 - 0.00011 21.8 0.1 0.00017 21.2 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 KIY51496.1 - 1.3e-05 24.9 0.1 0.00012 21.7 0.0 2.3 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIY51497.1 - 2.7e-06 28.0 0.3 9.3e-06 26.3 0.3 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase adh_short_C2 PF13561.6 KIY51498.1 - 6.4e-45 153.5 2.3 8.5e-44 149.8 2.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51498.1 - 1.5e-37 128.9 3.5 8.6e-36 123.2 3.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51498.1 - 1.7e-08 34.6 0.2 2.4e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF1482 PF07358.11 KIY51498.1 - 0.026 14.4 0.4 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1482) Transp_cyt_pur PF02133.15 KIY51499.1 - 6.3e-134 447.1 34.0 7.2e-134 446.9 34.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin F-box-like PF12937.7 KIY51501.1 - 3.4e-09 36.4 0.0 1.7e-08 34.2 0.0 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY51501.1 - 0.0012 18.7 0.4 0.056 13.3 0.1 3.3 2 1 0 2 2 2 1 F-box domain IMPa_N_2 PF18650.1 KIY51501.1 - 0.03 13.6 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Trimer_CC PF08954.11 KIY51501.1 - 0.14 11.8 0.1 0.48 10.0 0.0 1.9 2 0 0 2 2 2 0 Trimerisation motif Peptidase_M20 PF01546.28 KIY51502.1 - 2.7e-14 53.4 0.0 3.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY51502.1 - 0.00012 22.0 0.0 0.00051 19.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Adeno_IVa2 PF02456.15 KIY51502.1 - 0.1 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Pkinase PF00069.25 KIY51503.1 - 0.0024 17.3 0.0 0.0027 17.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Alpha_kinase PF02816.18 KIY51504.1 - 1.6e-20 74.0 0.0 3.5e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Alpha-kinase family zf-C3HC4 PF00097.25 KIY51504.1 - 0.071 13.0 10.8 0.19 11.7 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY51504.1 - 9 6.3 9.9 5.7 6.9 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) GCP_C_terminal PF04130.13 KIY51507.1 - 2.3e-16 60.2 0.0 3.2e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal XPG_N PF00752.17 KIY51508.1 - 4.1e-32 110.7 0.0 9.7e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIY51508.1 - 4e-28 97.6 0.0 9.6e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KIY51508.1 - 1.8e-05 25.3 0.0 4.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold CDC45 PF02724.14 KIY51508.1 - 3.8 5.7 8.7 6 5.0 8.7 1.4 1 0 0 1 1 1 0 CDC45-like protein YTH PF04146.15 KIY51509.1 - 1e-59 201.2 0.1 2.3e-59 200.1 0.1 1.6 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KIY51509.1 - 7.2e-06 25.7 0.0 0.058 13.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TANGO2 PF05742.12 KIY51510.1 - 2.3e-42 145.8 0.0 1.4e-30 107.2 0.0 2.0 2 0 0 2 2 2 2 Transport and Golgi organisation 2 LNP1 PF15419.6 KIY51511.1 - 0.021 15.0 0.6 0.026 14.8 0.6 1.2 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 MFS_1 PF07690.16 KIY51512.1 - 3.7e-35 121.5 24.0 5.5e-35 120.9 24.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-MYND PF01753.18 KIY51513.1 - 3.7e-09 36.5 9.9 5.8e-09 35.9 9.9 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KIY51513.1 - 0.42 10.5 11.7 0.094 12.6 8.5 1.6 2 0 0 2 2 2 0 HIT zinc finger RRM_1 PF00076.22 KIY51514.1 - 5.4e-09 35.7 1.1 0.0016 18.3 0.0 4.0 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_L PF01193.24 KIY51514.1 - 0.03 13.7 0.0 0.056 12.9 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Na_H_Exchanger PF00999.21 KIY51515.1 - 1.1e-59 202.2 20.1 1.5e-59 201.7 20.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SabA_adhesion PF18304.1 KIY51515.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain IBN_N PF03810.19 KIY51516.1 - 3.4e-05 23.7 0.0 0.0015 18.4 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 KIY51516.1 - 0.00011 22.2 0.2 2 8.9 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat Xpo1 PF08389.12 KIY51516.1 - 0.00045 20.3 0.1 0.067 13.3 0.0 3.5 2 1 0 2 2 2 1 Exportin 1-like protein RIX1 PF08167.12 KIY51516.1 - 0.0011 18.8 0.1 0.0053 16.5 0.1 2.2 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 KIY51516.1 - 0.002 18.3 0.1 0.01 16.0 0.1 2.4 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 Cse1 PF08506.10 KIY51516.1 - 0.0025 16.7 0.0 0.0062 15.4 0.0 1.6 1 0 0 1 1 1 1 Cse1 Cnd1 PF12717.7 KIY51516.1 - 0.017 15.1 2.7 0.5 10.4 0.1 4.1 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIY51516.1 - 0.056 14.0 0.4 4.6 7.9 0.0 4.3 6 0 0 6 6 6 0 HEAT-like repeat Pkinase PF00069.25 KIY51517.1 - 1.8e-48 165.2 0.0 2.1e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51517.1 - 1.1e-23 83.9 0.0 1.2e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KIY51517.1 - 4.7e-06 25.8 0.2 6.5e-06 25.4 0.2 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KIY51517.1 - 8.1e-06 25.4 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY51517.1 - 0.0012 18.9 0.0 0.0045 16.9 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY51517.1 - 0.022 14.1 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY51517.1 - 0.063 12.0 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Nop PF01798.18 KIY51519.1 - 3.2e-86 288.5 3.3 1.4e-85 286.4 0.0 2.4 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KIY51519.1 - 4.7e-20 71.7 0.6 4.7e-20 71.7 0.6 2.8 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DOT1 PF08123.13 KIY51519.1 - 0.091 12.3 0.1 0.28 10.7 0.1 1.8 1 0 0 1 1 1 0 Histone methylation protein DOT1 Actin PF00022.19 KIY51520.1 - 1.2e-77 261.2 0.0 6.6e-77 258.8 0.0 1.8 1 1 0 1 1 1 1 Actin FAM176 PF14851.6 KIY51520.1 - 0.54 9.9 1.8 0.89 9.2 1.8 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KIY51520.1 - 0.65 9.3 4.7 0.98 8.7 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KIY51520.1 - 9.2 6.3 6.5 17 5.4 6.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Kin17_mid PF10357.9 KIY51521.1 - 2.1e-48 163.4 0.1 2.1e-48 163.4 0.1 1.5 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KIY51521.1 - 0.00046 20.5 5.6 0.0013 19.1 5.6 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY51521.1 - 0.021 15.1 4.6 0.048 14.0 4.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIY51521.1 - 0.05 13.9 1.5 0.05 13.9 1.5 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_clus PF00172.18 KIY51522.1 - 5.1e-09 36.1 7.2 7e-09 35.7 7.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSS PF03034.15 KIY51523.1 - 5.5e-114 380.5 13.3 7.3e-114 380.1 13.3 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase Claudin_3 PF06653.11 KIY51523.1 - 0.031 14.2 0.9 1.3 8.9 0.9 2.8 2 1 0 2 2 2 0 Tight junction protein, Claudin-like PET PF06297.14 KIY51523.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 PET Domain TMEM169 PF15052.6 KIY51523.1 - 7.8 6.6 9.8 8.5 6.5 3.0 2.7 2 0 0 2 2 2 0 TMEM169 protein family ANAPC2 PF08672.11 KIY51524.1 - 4.5e-16 59.1 0.0 1e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 KIY51524.1 - 7.1e-15 54.7 0.0 1.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Cullin family zf-RING_6 PF14835.6 KIY51525.1 - 0.0002 21.2 2.9 0.00033 20.5 2.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KIY51525.1 - 0.17 12.3 15.1 0.3 11.5 15.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KIY51525.1 - 0.27 11.3 13.8 0.47 10.4 13.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Corona_nucleoca PF00937.18 KIY51525.1 - 0.54 9.2 8.1 0.85 8.6 8.1 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein F-box-like PF12937.7 KIY51526.1 - 3.3e-06 26.9 2.4 3.3e-06 26.9 2.4 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY51526.1 - 4.4e-06 26.4 0.0 2.9e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 F-box domain DUF2635 PF10948.8 KIY51526.1 - 0.016 14.9 0.1 0.85 9.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2635) Coa1 PF08695.10 KIY51527.1 - 2.2e-29 101.5 0.0 2.6e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TPR_21 PF09976.9 KIY51527.1 - 0.0071 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain RNase_PH PF01138.21 KIY51528.1 - 3.2e-17 63.3 1.7 4.9e-17 62.7 1.7 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_S9 PF00326.21 KIY51529.1 - 4.5e-07 29.6 0.0 9.3e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family TAF PF02969.17 KIY51530.1 - 6.2e-26 90.4 0.0 1.6e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 KIY51530.1 - 6.1e-15 55.3 1.1 9.8e-15 54.7 0.2 1.8 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 KIY51530.1 - 3.4e-05 24.2 0.1 7e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIY51530.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HEAT_EZ PF13513.6 KIY51530.1 - 0.087 13.4 9.6 0.86 10.2 0.2 4.3 2 2 2 4 4 4 0 HEAT-like repeat CBFD_NFYB_HMF PF00808.23 KIY51530.1 - 0.17 12.2 0.1 0.47 10.8 0.1 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Romo1 PF10247.9 KIY51530.1 - 0.19 12.1 0.8 0.41 11.0 0.8 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 HEAT PF02985.22 KIY51530.1 - 0.21 11.9 0.7 1.8 9.1 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat BTB PF00651.31 KIY51531.1 - 1.1e-07 32.1 0.0 3e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain SR-25 PF10500.9 KIY51531.1 - 0.047 13.3 3.0 0.062 12.9 3.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sugar_tr PF00083.24 KIY51532.1 - 3e-42 145.0 15.8 3.9e-42 144.7 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY51532.1 - 1.3e-17 63.8 28.1 1.1e-10 41.1 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LysM PF01476.20 KIY51533.1 - 4.2e-10 39.5 0.0 6.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 LysM domain Pkinase PF00069.25 KIY51534.1 - 8.5e-69 231.8 0.0 1.1e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51534.1 - 8.5e-36 123.5 0.0 1.5e-34 119.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY51534.1 - 0.00036 20.0 0.0 0.00095 18.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIY51534.1 - 0.0033 16.3 0.0 0.0054 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KIY51534.1 - 0.051 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KIY51534.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIY51534.1 - 0.063 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY51534.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain WD40 PF00400.32 KIY51537.1 - 1.1e-25 89.4 2.1 1.3e-06 29.0 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY51537.1 - 2.8e-11 43.5 0.0 0.28 11.5 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY51537.1 - 0.00074 18.3 0.3 0.0079 14.9 0.1 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY51537.1 - 0.022 14.1 0.0 0.2 11.0 0.0 2.4 1 1 2 3 3 3 0 WD40-like domain Bromo_MP PF01573.16 KIY51537.1 - 0.024 14.0 0.0 0.057 12.7 0.0 1.6 2 0 0 2 2 2 0 Bromovirus movement protein Cytochrom_D1 PF02239.16 KIY51537.1 - 0.043 12.3 0.0 0.12 10.8 0.0 1.8 2 1 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIY51537.1 - 0.094 11.7 0.5 2.1 7.2 0.1 2.9 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HAD_2 PF13419.6 KIY51538.1 - 1.4e-15 57.8 0.0 1.2e-10 41.7 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY51538.1 - 2.6e-13 50.8 0.0 8.8e-13 49.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY51538.1 - 5.7e-07 29.5 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Glyco_hydro_61 PF03443.14 KIY51539.1 - 3.1e-49 167.7 0.0 1.2e-48 165.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Pfk_N PF18468.1 KIY51539.1 - 0.063 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast PrpF PF04303.13 KIY51542.1 - 2e-73 247.5 0.1 2.3e-73 247.3 0.1 1.0 1 0 0 1 1 1 1 PrpF protein zf-C2H2 PF00096.26 KIY51543.1 - 2.1e-12 46.8 10.7 3e-06 27.4 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY51543.1 - 8.9e-09 35.5 8.2 0.00069 20.2 2.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY51543.1 - 6.9e-06 26.2 11.7 0.00011 22.5 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KIY51543.1 - 0.00041 20.7 0.7 0.011 16.2 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY51543.1 - 0.0088 16.3 1.6 0.49 10.8 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KIY51543.1 - 0.029 14.0 0.4 0.065 12.9 0.1 1.6 2 0 0 2 2 2 0 MYST family zinc finger domain FOXP-CC PF16159.5 KIY51543.1 - 0.075 13.7 1.0 0.15 12.7 0.2 1.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 KIY51543.1 - 0.49 10.4 5.3 2 8.4 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KIY51543.1 - 1.8 8.7 6.9 0.49 10.5 0.5 2.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIY51543.1 - 3.7 7.4 13.0 4.1 7.2 0.2 3.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Steroid_dh PF02544.16 KIY51544.1 - 3.6e-25 88.7 8.3 1.5e-08 34.8 0.2 3.2 2 1 1 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KIY51544.1 - 0.0019 17.8 2.2 0.012 15.1 2.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Sugar_tr PF00083.24 KIY51546.1 - 5e-107 358.6 12.1 5.8e-107 358.4 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY51546.1 - 3.9e-27 95.1 27.2 1.7e-19 70.0 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1156 PF06634.12 KIY51546.1 - 2 8.6 3.5 9 6.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1156) Pex24p PF06398.11 KIY51547.1 - 4e-17 62.3 13.6 2.2e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin PRT_C PF08372.10 KIY51547.1 - 0.24 11.1 2.1 0.58 9.9 0.1 2.0 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Myco_19_kDa PF05481.12 KIY51548.1 - 0.092 13.0 0.4 20 5.5 0.0 2.8 2 1 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen DUF2235 PF09994.9 KIY51549.1 - 5e-80 268.9 0.0 6.1e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) A_deaminase PF00962.22 KIY51550.1 - 1e-104 350.4 0.0 1.5e-51 175.7 0.0 2.1 1 1 1 2 2 2 2 Adenosine/AMP deaminase Glyco_hyd_65N_2 PF14498.6 KIY51551.1 - 0.047 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain MFS_1 PF07690.16 KIY51552.1 - 2.8e-31 108.7 44.0 1e-21 77.3 12.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY51552.1 - 2e-18 66.5 5.1 2e-18 66.5 5.1 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KIY51552.1 - 3 7.0 30.6 0.018 14.3 5.1 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Ebp2 PF05890.12 KIY51553.1 - 2.1e-79 266.9 10.6 3.4e-79 266.2 10.6 1.3 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 CsbD PF05532.12 KIY51554.1 - 0.069 13.1 4.0 0.18 11.8 4.0 1.7 1 0 0 1 1 1 0 CsbD-like p450 PF00067.22 KIY51555.1 - 2e-54 185.1 0.0 4.2e-54 184.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NPH3 PF03000.14 KIY51555.1 - 0.013 15.2 0.2 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 NPH3 family NIF PF03031.18 KIY51557.1 - 1.4e-06 28.2 0.0 2.7e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase BHD_3 PF10405.9 KIY51558.1 - 3.8e-29 100.9 0.1 9.2e-29 99.7 0.1 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KIY51558.1 - 2e-23 82.7 0.3 1.9e-22 79.5 0.3 2.6 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KIY51558.1 - 1.8e-20 72.5 0.0 5.2e-20 71.0 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KIY51558.1 - 3.3e-14 53.6 0.0 3.3e-14 53.6 0.0 3.7 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KIY51558.1 - 0.00025 21.5 0.0 0.0016 18.8 0.0 2.4 1 1 0 1 1 1 1 Transglutaminase-like superfamily GCD14 PF08704.10 KIY51559.1 - 8.5e-92 307.3 0.3 4.2e-90 301.7 0.3 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KIY51559.1 - 3.3e-06 27.0 0.0 6.2e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY51559.1 - 1.2e-05 25.2 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KIY51559.1 - 0.0018 19.0 0.0 0.0042 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 KIY51559.1 - 0.0043 16.2 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_24 PF13578.6 KIY51559.1 - 0.022 15.8 0.3 0.083 13.9 0.2 2.0 1 1 1 2 2 2 0 Methyltransferase domain GCD14_N PF14801.6 KIY51559.1 - 0.039 13.8 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Ubie_methyltran PF01209.18 KIY51559.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 KIY51560.1 - 6e-22 78.0 0.1 5.9e-21 74.8 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY51560.1 - 2.9e-13 49.6 0.0 7.3e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY51560.1 - 6.4e-05 24.0 0.0 0.00012 23.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIY51560.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 KIY51560.1 - 0.0073 16.1 0.2 0.011 15.5 0.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 KIY51560.1 - 0.039 13.2 0.2 0.062 12.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_S9 PF00326.21 KIY51562.1 - 6e-35 120.6 0.0 1.1e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KIY51562.1 - 3.1e-08 33.4 0.0 6.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KIY51562.1 - 2.3e-06 27.1 0.0 0.00032 20.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY51562.1 - 6e-06 26.1 0.3 3.2e-05 23.7 0.3 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 KIY51562.1 - 2.4e-05 23.2 0.0 0.0036 16.0 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KIY51562.1 - 2.7e-05 23.9 0.0 0.00043 19.9 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KIY51562.1 - 0.0042 17.0 0.0 0.059 13.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KIY51562.1 - 0.06 11.8 0.0 0.096 11.2 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 KIY51562.1 - 0.078 13.6 0.6 0.29 11.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Avl9 PF09794.9 KIY51564.1 - 9.5e-122 406.3 0.0 1.2e-121 406.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KIY51564.1 - 3.3e-09 36.7 0.1 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KIY51564.1 - 5.1e-07 29.6 0.6 0.019 14.6 1.5 3.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 KIY51564.1 - 0.55 10.2 2.4 5.1 7.0 0.4 3.0 3 1 1 4 4 4 0 DENN (AEX-3) domain ACCA PF03255.14 KIY51567.1 - 0.044 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Plavaka PF18759.1 KIY51568.1 - 9.3e-19 67.8 3.4 1e-17 64.4 2.9 2.1 2 0 0 2 2 2 1 Plavaka transposase DUF3741 PF12552.8 KIY51568.1 - 0.039 13.9 0.1 0.081 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) TM1586_NiRdase PF14512.6 KIY51569.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase 5-nucleotidase PF06189.12 KIY51569.1 - 0.039 12.9 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase FAD_oxidored PF12831.7 KIY51570.1 - 0.05 13.0 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase AMP-binding PF00501.28 KIY51572.1 - 3.2e-66 223.7 0.0 4.5e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY51572.1 - 5.6e-07 30.5 0.0 1.6e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidase PF01425.21 KIY51573.1 - 1.7e-65 221.8 0.1 1.4e-62 212.2 0.1 2.1 2 0 0 2 2 2 2 Amidase DHHC PF01529.20 KIY51574.1 - 1.2e-31 109.6 5.2 1.2e-31 109.6 5.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Sugar_tr PF00083.24 KIY51575.1 - 4.3e-79 266.5 20.4 5.4e-79 266.2 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY51575.1 - 7.2e-24 84.4 33.0 7.2e-24 84.4 33.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily CopD PF05425.13 KIY51575.1 - 0.021 15.2 4.8 0.14 12.6 4.8 2.4 1 0 0 1 1 1 0 Copper resistance protein D ATP_bind_1 PF03029.17 KIY51576.1 - 7.2e-77 258.4 0.0 1.2e-76 257.7 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein T2SSE PF00437.20 KIY51576.1 - 2.9e-05 23.3 0.0 4.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KIY51576.1 - 0.00029 21.3 0.0 0.0017 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY51576.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIY51576.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KIY51576.1 - 0.0016 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 KIY51576.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KIY51576.1 - 0.0038 17.8 0.0 0.0086 16.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KIY51576.1 - 0.0044 17.2 0.0 0.0084 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY51576.1 - 0.0057 16.4 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ArsA_ATPase PF02374.15 KIY51576.1 - 0.0088 15.3 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA PF00004.29 KIY51576.1 - 0.0097 16.3 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIY51576.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 KIY51576.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 KIY51576.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIY51576.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.12 KIY51576.1 - 0.017 14.1 0.0 0.034 13.1 0.0 1.5 1 0 0 1 1 1 0 YcjX-like family, DUF463 APS_kinase PF01583.20 KIY51576.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoH PF02562.16 KIY51576.1 - 0.02 14.4 0.0 0.081 12.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.19 KIY51576.1 - 0.024 14.2 0.2 0.05 13.2 0.2 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 KIY51576.1 - 0.024 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KIY51576.1 - 0.037 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 NTPase CbiA PF01656.23 KIY51576.1 - 0.038 14.1 0.0 0.058 13.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KIY51576.1 - 0.044 13.0 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIY51576.1 - 0.045 13.5 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KIY51576.1 - 0.046 13.2 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KIY51576.1 - 0.047 13.0 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CLP1_P PF16575.5 KIY51576.1 - 0.05 13.4 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Mg_chelatase PF01078.21 KIY51576.1 - 0.055 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PRK PF00485.18 KIY51576.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 KIY51576.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KIY51576.1 - 0.084 13.4 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIY51576.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RecA PF00154.21 KIY51576.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein NB-ARC PF00931.22 KIY51576.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.18 KIY51576.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_5 PF07728.14 KIY51576.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 KIY51576.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CobU PF02283.16 KIY51576.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Mago-bind PF09282.10 KIY51577.1 - 1.2e-14 53.8 1.7 2.1e-14 53.0 1.7 1.4 1 0 0 1 1 1 1 Mago binding CDC27 PF09507.10 KIY51577.1 - 0.0017 17.8 1.4 0.0017 17.8 1.4 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PBP1_TM PF14812.6 KIY51577.1 - 0.0061 16.9 3.9 0.011 16.0 3.9 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Uso1_p115_C PF04871.13 KIY51577.1 - 0.063 13.7 4.9 0.099 13.0 4.9 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TctA PF01970.16 KIY51577.1 - 0.19 10.4 0.0 0.2 10.4 0.0 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Ribosomal_60s PF00428.19 KIY51577.1 - 3.6 8.2 7.4 1.4 9.5 5.3 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein DUF1640 PF07798.11 KIY51578.1 - 1.3e-43 149.0 5.1 1.5e-43 148.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Fzo_mitofusin PF04799.13 KIY51578.1 - 0.00093 18.8 1.7 0.062 12.8 1.0 2.3 2 0 0 2 2 2 2 fzo-like conserved region Baculo_PEP_C PF04513.12 KIY51578.1 - 0.046 13.8 3.1 0.091 12.8 3.1 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.6 KIY51578.1 - 0.18 12.4 4.4 0.92 10.2 2.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 KIY51578.1 - 0.22 11.6 5.2 0.58 10.2 3.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.12 KIY51578.1 - 0.43 10.5 4.5 0.9 9.4 1.8 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Col_cuticle_N PF01484.17 KIY51578.1 - 1.9 8.6 5.7 18 5.5 1.5 2.6 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain CPSF_A PF03178.15 KIY51579.1 - 7.2e-79 265.4 0.0 1.1e-78 264.9 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region DnaJ PF00226.31 KIY51580.1 - 1e-15 57.6 0.1 2.7e-15 56.2 0.1 1.7 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KIY51580.1 - 9.5e-12 44.5 0.2 1.3e-11 44.0 0.2 1.2 1 0 0 1 1 1 1 CSL zinc finger Pet191_N PF10203.9 KIY51582.1 - 5.5e-28 97.1 5.8 6e-28 96.9 5.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KIY51582.1 - 0.025 14.7 4.0 0.95 9.7 0.2 2.4 2 0 0 2 2 2 0 CHCH domain GST_N PF02798.20 KIY51583.1 - 5.7e-14 52.2 0.0 1.4e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY51583.1 - 3.9e-11 43.0 0.0 7.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY51583.1 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY51583.1 - 2.3e-08 34.3 0.0 4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY51583.1 - 0.00019 21.4 0.0 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY51583.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spem1 PF15670.5 KIY51584.1 - 0.05 13.2 10.3 0.061 12.9 10.3 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Auto_anti-p27 PF06677.12 KIY51586.1 - 1.4e-24 85.9 8.1 4.4e-14 52.3 1.6 3.2 3 0 0 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR PF01485.21 KIY51586.1 - 0.16 12.2 3.8 0.34 11.2 0.3 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain HNF-1_N PF04814.13 KIY51586.1 - 0.41 11.2 5.0 0.52 10.9 0.7 2.1 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Glyco_hydro_47 PF01532.20 KIY51587.1 - 4.8e-113 378.5 0.0 6.5e-113 378.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KIY51587.1 - 7e-06 26.0 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PA domain Pribosyltran PF00156.27 KIY51588.1 - 1.1e-12 47.8 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIY51588.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase F-box-like PF12937.7 KIY51589.1 - 0.00025 20.9 3.2 0.00082 19.2 0.1 3.0 3 0 0 3 3 3 1 F-box-like Zn_clus PF00172.18 KIY51590.1 - 2.3e-11 43.6 8.3 2.8e-11 43.3 8.3 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_2 PF13532.6 KIY51591.1 - 7.1e-14 52.5 0.0 1e-12 48.6 0.0 2.0 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily FtsJ PF01728.19 KIY51592.1 - 1.7e-10 41.3 0.0 2.3e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase APH PF01636.23 KIY51593.1 - 2.1e-24 86.8 0.1 3.2e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY51594.1 - 5.6e-44 150.5 0.0 8.5e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51594.1 - 3.1e-22 79.1 0.0 1.7e-21 76.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIY51594.1 - 6.3e-14 52.1 0.2 3.1e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KIY51594.1 - 0.00076 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KIY51594.1 - 0.035 13.5 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY51594.1 - 0.14 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SKG6 PF08693.10 KIY51595.1 - 5.6e-07 28.9 2.7 1.9e-06 27.2 2.7 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KIY51595.1 - 0.013 16.3 0.0 0.038 14.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 KIY51595.1 - 0.055 12.3 0.9 0.08 11.8 0.9 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF1180 PF06679.12 KIY51595.1 - 0.072 13.5 0.1 0.072 13.5 0.1 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF1180) RIFIN PF02009.16 KIY51595.1 - 0.25 11.2 1.4 0.43 10.4 1.4 1.4 1 1 0 1 1 1 0 Rifin PLA2_B PF01735.18 KIY51596.1 - 2.7e-89 299.8 0.1 4.1e-89 299.3 0.1 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IMPa_N_2 PF18650.1 KIY51596.1 - 0.019 14.2 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain DEAD PF00270.29 KIY51597.1 - 2.4e-18 66.5 0.0 4.9e-18 65.5 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY51597.1 - 9.8e-06 25.9 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 KIY51598.1 - 2.2e-34 116.9 33.8 2.3e-05 25.1 0.5 9.7 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY51598.1 - 8e-11 42.1 3.0 0.023 15.0 0.0 7.4 5 2 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain adh_short_C2 PF13561.6 KIY51599.1 - 1.9e-56 191.3 2.0 2.2e-56 191.1 2.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51599.1 - 1.2e-47 161.9 1.0 1.6e-47 161.5 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51599.1 - 2.9e-16 59.9 1.0 4.2e-16 59.4 1.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY51599.1 - 0.0026 17.3 0.3 0.005 16.3 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIY51599.1 - 0.024 14.0 0.1 0.057 12.7 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1771 PF08590.10 KIY51599.1 - 0.14 12.5 0.4 0.41 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) DFP PF04127.15 KIY51599.1 - 1.5 8.6 4.5 3.9 7.3 0.5 2.5 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Ribosomal_S3Ae PF01015.18 KIY51600.1 - 1.6e-94 315.2 1.6 1.9e-94 314.9 1.6 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KIY51600.1 - 0.031 13.9 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region LMP PF04778.12 KIY51600.1 - 0.035 14.0 0.2 0.056 13.4 0.2 1.4 1 0 0 1 1 1 0 LMP repeated region Autophagy_act_C PF03987.15 KIY51601.1 - 5.8e-19 68.4 0.5 9.3e-19 67.8 0.5 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Thiolase_N PF00108.23 KIY51602.1 - 9.6e-87 290.6 2.4 1.3e-86 290.2 2.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY51602.1 - 8.6e-38 128.8 1.2 8.6e-38 128.8 1.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIY51602.1 - 0.00056 19.6 4.5 0.028 14.0 2.4 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Dynamin_N PF00350.23 KIY51603.1 - 2.6e-19 69.9 0.0 2.6e-19 69.9 0.0 3.4 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KIY51603.1 - 5.5e-07 29.7 1.7 9.8e-05 22.4 0.2 3.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY51603.1 - 0.00097 19.1 0.2 0.0058 16.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KIY51603.1 - 0.0012 19.4 0.6 0.011 16.3 0.1 2.6 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KIY51603.1 - 0.0019 18.5 0.0 0.0083 16.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY51603.1 - 0.006 17.0 4.7 0.069 13.5 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain IIGP PF05049.13 KIY51603.1 - 0.02 13.9 0.0 0.24 10.4 0.0 2.5 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.6 KIY51603.1 - 0.036 14.6 0.0 0.036 14.6 0.0 4.4 3 1 1 4 4 4 0 AAA domain Roc PF08477.13 KIY51603.1 - 0.086 13.1 0.0 0.42 10.8 0.0 2.2 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIY51603.1 - 0.15 11.8 0.1 0.45 10.3 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AIG1 PF04548.16 KIY51603.1 - 0.98 8.7 0.0 0.98 8.7 0.0 3.2 4 0 0 4 4 4 0 AIG1 family Complex1_LYR_2 PF13233.6 KIY51605.1 - 9.2e-20 71.2 2.3 1.2e-19 70.9 2.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF5343 PF17278.2 KIY51605.1 - 0.064 13.3 0.5 0.083 13.0 0.5 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5343) Sua5_yciO_yrdC PF01300.18 KIY51606.1 - 2.3e-52 177.1 0.0 6.3e-52 175.7 0.0 1.6 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 KIY51606.1 - 5.4e-28 98.2 0.0 7.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding HMG_box PF00505.19 KIY51607.1 - 2.6e-13 50.2 0.1 4.2e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY51607.1 - 0.0012 19.4 0.2 0.0024 18.4 0.0 1.6 2 0 0 2 2 2 1 HMG-box domain DUF302 PF03625.14 KIY51608.1 - 4.4e-08 32.9 0.0 7.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF302 MFS_1 PF07690.16 KIY51609.1 - 6e-39 134.0 19.3 6e-39 134.0 19.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TMEM100 PF16311.5 KIY51609.1 - 0.12 11.9 2.6 6 6.5 0.0 3.1 2 1 1 3 3 3 0 Transmembrane protein 100 zf-C3HC4 PF00097.25 KIY51610.1 - 3.2e-08 33.3 2.0 1.5e-07 31.2 2.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY51610.1 - 2.6e-07 30.8 6.9 6.9e-07 29.5 3.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY51610.1 - 5.7e-06 26.1 7.3 2.1e-05 24.3 2.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY51610.1 - 1e-05 25.7 1.3 1e-05 25.7 1.3 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KIY51610.1 - 1.9e-05 24.4 5.9 0.0001 22.1 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY51610.1 - 2.4e-05 24.1 2.3 6.9e-05 22.6 0.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIY51610.1 - 0.00025 20.8 6.4 0.00059 19.6 4.1 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KIY51610.1 - 0.00052 20.0 1.2 0.0034 17.4 0.6 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KIY51610.1 - 0.00066 19.7 6.8 0.001 19.0 1.5 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIY51610.1 - 0.0011 18.8 4.0 0.0029 17.5 1.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIY51610.1 - 0.0052 16.9 3.6 0.0052 16.9 3.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF1244 PF06844.11 KIY51610.1 - 0.028 14.6 0.8 0.09 12.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) IBR PF01485.21 KIY51610.1 - 0.14 12.4 3.1 0.4 11.0 3.1 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Zn-C2H2_12 PF18112.1 KIY51610.1 - 0.39 11.2 3.7 5.7 7.5 0.2 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_10 PF16685.5 KIY51610.1 - 1.8 8.7 4.2 0.79 9.9 1.5 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 FANCL_C PF11793.8 KIY51610.1 - 7.8 6.8 8.2 3.3 8.0 4.5 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain tRNA-synt_2c PF01411.19 KIY51611.1 - 2.4e-07 29.7 0.0 3.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KIY51611.1 - 0.0009 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DJ-1_PfpI PF01965.24 KIY51612.1 - 2.1e-12 47.1 0.0 4e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIY51612.1 - 0.0002 21.1 0.0 0.0019 17.9 0.0 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KIY51613.1 - 3e-12 46.7 0.1 5e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIY51613.1 - 0.00027 20.7 0.0 0.0034 17.1 0.0 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like NIF PF03031.18 KIY51614.1 - 4.1e-44 150.1 0.0 4.6e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hormone_2 PF00123.20 KIY51614.1 - 0.17 11.8 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Peptide hormone Cyt-b5 PF00173.28 KIY51615.1 - 1.1e-17 63.9 0.0 1.2e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phage-MuB_C PF09077.11 KIY51615.1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Mu B transposition protein, C terminal 4HBT PF03061.22 KIY51616.1 - 8.5e-06 26.0 1.2 0.064 13.6 0.0 3.1 3 1 0 3 3 3 2 Thioesterase superfamily efThoc1 PF11957.8 KIY51618.1 - 0.082 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor PH PF00169.29 KIY51619.1 - 1.1e-10 41.9 0.0 2.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KIY51619.1 - 0.00078 19.8 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain Ras PF00071.22 KIY51621.1 - 3.3e-45 153.6 0.2 3.8e-45 153.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY51621.1 - 1.3e-15 57.7 0.0 1.8e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY51621.1 - 9.5e-06 25.2 0.0 1.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.6 KIY51621.1 - 0.00099 19.1 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KIY51621.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY51621.1 - 0.0017 18.0 0.0 0.0062 16.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KIY51621.1 - 0.012 15.6 0.2 0.02 14.8 0.2 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KIY51621.1 - 0.14 12.0 0.0 13 5.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GST_N PF02798.20 KIY51622.1 - 3.5e-15 56.1 0.1 7.6e-15 55.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY51622.1 - 3.2e-10 40.3 0.0 6.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY51622.1 - 1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY51622.1 - 8.6e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY51622.1 - 9.3e-05 22.6 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 KIY51623.1 - 1.8e-18 66.1 0.0 3.3e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY51623.1 - 0.00042 20.1 0.1 0.023 14.6 0.0 2.6 2 1 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KIY51623.1 - 0.0044 16.6 0.0 0.059 13.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim54 PF11711.8 KIY51623.1 - 0.01 14.6 1.2 0.015 14.1 1.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RXT2_N PF08595.11 KIY51623.1 - 0.13 12.2 3.0 0.22 11.5 3.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal TRAM_LAG1_CLN8 PF03798.16 KIY51624.1 - 6.7e-38 130.4 19.4 9.5e-38 129.9 19.4 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KIY51624.1 - 1.9e-08 33.8 0.0 1.9e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 TRAM1-like protein DUF4481 PF14800.6 KIY51624.1 - 0.048 13.1 0.5 0.048 13.1 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) BTB PF00651.31 KIY51625.1 - 0.045 14.0 0.1 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain Pardaxin PF07425.11 KIY51625.1 - 0.39 10.4 1.8 23 4.7 0.0 2.4 2 0 0 2 2 2 0 Pardaxin DEAD PF00270.29 KIY51626.1 - 4.7e-43 147.0 0.0 7.1e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY51626.1 - 1.6e-25 89.6 0.0 5.6e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY51626.1 - 0.0094 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mob1_phocein PF03637.17 KIY51627.1 - 2.8e-78 261.7 0.0 3.3e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family RNA_pol_Rpc4 PF05132.14 KIY51628.1 - 0.12 12.7 4.4 0.14 12.5 4.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 KIY51628.1 - 0.81 7.9 11.9 0.83 7.9 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 KIY51628.1 - 5.9 6.4 20.9 8.2 6.0 20.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F-box-like PF12937.7 KIY51629.1 - 4.1e-05 23.4 0.4 0.00012 21.8 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY51629.1 - 0.00017 21.4 0.2 0.00057 19.7 0.2 1.9 1 0 0 1 1 1 1 F-box domain FAA_hydrolase PF01557.18 KIY51630.1 - 4.7e-54 183.4 0.0 6.1e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Chitin_synth_1 PF01644.17 KIY51631.1 - 2.8e-66 222.5 0.1 6.8e-66 221.3 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIY51631.1 - 1.3e-28 98.7 0.5 3.4e-28 97.4 0.5 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIY51631.1 - 3.7e-23 81.9 0.0 5.1e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY51631.1 - 4.6e-08 33.2 0.1 4.6e-08 33.2 0.1 2.8 1 1 1 2 2 2 1 Glycosyl transferase family group 2 zf-C3HC4_2 PF13923.6 KIY51632.1 - 1.4e-07 31.3 6.0 1.7e-06 27.8 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY51632.1 - 5.9e-07 29.7 6.6 9.2e-06 25.9 2.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KIY51632.1 - 6.2e-07 29.2 3.7 1.2e-06 28.3 2.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY51632.1 - 1.4e-06 28.0 4.1 3.1e-05 23.7 0.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY51632.1 - 9.8e-06 25.5 6.7 2.8e-05 24.1 0.8 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIY51632.1 - 1.3e-05 25.0 4.7 0.00024 21.0 0.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY51632.1 - 0.00011 22.0 6.9 0.00039 20.2 1.6 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 KIY51632.1 - 0.00025 20.8 3.2 0.29 11.0 0.2 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 KIY51632.1 - 0.00051 20.1 6.5 0.00062 19.9 0.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KIY51632.1 - 0.00055 20.2 9.7 0.0048 17.1 10.0 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 KIY51632.1 - 0.0013 19.0 2.8 0.17 12.2 0.5 2.3 2 0 0 2 2 2 2 zinc-ribbon zf-C2HC5 PF06221.13 KIY51632.1 - 0.0031 17.4 1.4 0.021 14.8 0.1 2.1 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-ANAPC11 PF12861.7 KIY51632.1 - 0.0035 17.4 1.6 0.033 14.2 0.5 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KIY51632.1 - 0.0038 17.0 3.5 0.027 14.3 3.0 2.2 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KIY51632.1 - 0.0039 17.0 4.4 0.012 15.4 1.0 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KIY51632.1 - 0.0047 17.0 0.7 0.26 11.4 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding RING-finger Rtf2 PF04641.12 KIY51632.1 - 0.11 11.8 0.2 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger UBZ_FAAP20 PF15750.5 KIY51632.1 - 0.2 11.6 4.3 3.7 7.6 0.5 2.7 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Spo12 PF05032.12 KIY51633.1 - 4.3e-13 48.9 1.4 4.3e-13 48.9 1.4 2.0 2 0 0 2 2 2 1 Spo12 family Sec7 PF01369.20 KIY51634.1 - 2.5e-69 232.6 0.1 7.4e-69 231.1 0.1 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KIY51634.1 - 1.3e-35 122.7 5.2 1.8e-35 122.2 0.0 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KIY51634.1 - 5.2e-33 112.8 0.4 5.2e-33 112.8 0.4 6.0 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 KIY51634.1 - 8.2e-24 84.2 0.7 1.6e-20 73.5 0.1 3.8 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1539 PF07560.11 KIY51634.1 - 0.0042 17.2 0.5 3.2 7.8 0.0 3.5 4 0 0 4 4 4 2 Domain of Unknown Function (DUF1539) NopRA1 PF16201.5 KIY51634.1 - 0.098 12.2 0.6 1.4 8.5 0.0 3.1 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Arm PF00514.23 KIY51634.1 - 0.1 12.6 0.5 26 5.1 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat FANCI_S3 PF14677.6 KIY51634.1 - 0.12 12.1 3.0 0.31 10.7 0.1 2.9 2 0 0 2 2 2 0 FANCI solenoid 3 Polyketide_cyc PF03364.20 KIY51635.1 - 4e-25 88.5 0.0 4.7e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KIY51635.1 - 5.3e-06 26.8 0.0 6.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Aldedh PF00171.22 KIY51636.1 - 3.4e-163 543.4 1.4 3.9e-163 543.3 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Coiled-coil_56 PF09813.9 KIY51639.1 - 2.7e-06 27.4 0.1 5.6e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 NrsF PF06532.11 KIY51639.1 - 0.083 12.6 0.5 0.14 11.9 0.5 1.3 1 0 0 1 1 1 0 Negative regulator of sigma F CDC14 PF08045.11 KIY51640.1 - 8.1e-33 113.7 0.2 1e-16 60.9 0.0 3.2 3 0 0 3 3 3 3 Cell division control protein 14, SIN component UPF0029 PF01205.19 KIY51641.1 - 4.6e-31 107.3 0.0 6.9e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KIY51641.1 - 0.00025 21.3 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain Zn_clus PF00172.18 KIY51643.1 - 7.5e-06 26.0 5.7 1.5e-05 25.0 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.14 KIY51644.1 - 4.7e-29 101.7 1.8 3.8e-28 98.7 1.8 1.9 1 1 0 1 1 1 1 Phosphoesterase family Vps62 PF06101.11 KIY51645.1 - 0.0043 15.4 0.0 0.0059 15.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 ABC_membrane_3 PF13748.6 KIY51645.1 - 0.041 13.1 0.0 0.058 12.6 0.0 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region Lipase_3 PF01764.25 KIY51646.1 - 1.4e-23 83.3 0.0 2e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY51646.1 - 0.0082 16.8 0.4 0.012 16.3 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MinC_C PF03775.16 KIY51646.1 - 0.23 11.5 0.7 0.42 10.6 0.7 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain Sedlin_N PF04628.13 KIY51647.1 - 2.4e-19 69.7 0.2 3.2e-19 69.3 0.2 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MAS20 PF02064.15 KIY51648.1 - 6.8e-36 123.2 0.0 1.6e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 MAS20 protein import receptor SET PF00856.28 KIY51648.1 - 1e-12 48.7 0.0 2e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 SET domain Nif11 PF07862.11 KIY51648.1 - 0.14 12.5 0.4 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Nif11 domain GlcV_C_terminal PF17847.1 KIY51648.1 - 0.17 12.4 0.0 1.8 9.1 0.0 2.2 2 0 0 2 2 2 0 Glucose ABC transporter C-terminal domain RTA1 PF04479.13 KIY51649.1 - 7.8e-40 136.7 10.3 7.8e-40 136.7 10.3 1.3 1 1 0 1 1 1 1 RTA1 like protein HupE_UreJ PF04955.12 KIY51649.1 - 0.0089 15.5 1.5 0.016 14.7 1.5 1.4 1 0 0 1 1 1 1 HupE / UreJ protein UCH PF00443.29 KIY51650.1 - 5.6e-31 108.0 0.0 7.8e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY51650.1 - 0.0012 18.5 0.0 0.0031 17.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BLOC1_2 PF10046.9 KIY51651.1 - 0.039 14.3 2.9 3.6 8.0 0.1 3.7 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 KIY51651.1 - 0.095 12.5 0.7 2.6 7.9 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF4211 PF13926.6 KIY51651.1 - 0.36 10.9 5.9 0.28 11.3 0.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) SLX9 PF15341.6 KIY51651.1 - 6.5 7.2 9.8 0.49 10.8 3.3 2.6 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 BPL_LplA_LipB PF03099.19 KIY51652.1 - 5.2e-06 26.4 0.0 9.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 KIY51652.1 - 0.0048 16.9 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus MWFE PF15879.5 KIY51653.1 - 6.9e-23 80.6 0.0 8.4e-23 80.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit NTPase_I-T PF01931.18 KIY51654.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF84 TB2_DP1_HVA22 PF03134.19 KIY51655.1 - 3.1e-14 52.7 0.1 3.1e-14 52.7 0.1 1.9 2 1 0 2 2 2 1 TB2/DP1, HVA22 family G10 PF01125.17 KIY51656.1 - 3.9e-68 227.8 8.0 4.4e-68 227.7 8.0 1.0 1 0 0 1 1 1 1 G10 protein Na_H_Exchanger PF00999.21 KIY51657.1 - 1.4e-43 149.2 47.4 2e-43 148.6 47.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CX9C PF16860.5 KIY51658.1 - 0.089 12.8 6.5 0.78 9.8 0.1 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KIY51658.1 - 0.13 12.5 8.3 2.5 8.5 0.6 3.0 1 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KIY51658.1 - 8 6.7 10.0 13 6.1 0.4 2.3 2 0 0 2 2 2 0 CHCH domain DUF498 PF04430.14 KIY51659.1 - 1.1e-31 109.1 0.0 1.4e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) RRM_1 PF00076.22 KIY51661.1 - 5.7e-33 112.6 0.0 6.2e-17 61.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY51661.1 - 5.1e-05 23.3 0.0 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIY51661.1 - 0.00028 20.8 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KIY51661.1 - 0.0023 17.5 0.0 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY51661.1 - 0.0058 16.5 0.0 0.03 14.2 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KIY51661.1 - 0.031 14.4 0.1 0.31 11.2 0.0 2.5 3 1 0 3 3 3 0 RNA recognition motif Limkain-b1 PF11608.8 KIY51661.1 - 0.17 12.0 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Band_7 PF01145.25 KIY51662.1 - 7.2e-26 91.3 5.0 1.1e-25 90.7 5.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family RasGAP PF00616.19 KIY51663.1 - 4.7e-20 72.2 0.0 1.9e-12 47.3 0.0 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KIY51663.1 - 0.001 19.3 0.0 0.0034 17.5 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 KIY51663.1 - 0.0013 18.6 0.1 0.3 10.9 0.0 3.4 2 0 0 2 2 2 2 Cell morphogenesis C-terminal Pkinase PF00069.25 KIY51664.1 - 1.4e-42 145.9 0.0 8.5e-24 84.3 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51664.1 - 1.3e-10 41.0 0.0 5.1e-09 35.8 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KIY51664.1 - 2.5e-05 24.3 0.3 7.8e-05 22.7 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIY51664.1 - 0.16 11.6 0.0 0.48 10.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 KIY51665.1 - 9.7e-32 110.3 68.3 4.4e-27 94.9 35.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY51665.1 - 0.0023 16.4 2.5 0.0069 14.9 0.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Acp26Ab PF05777.12 KIY51665.1 - 0.016 15.8 0.4 0.045 14.4 0.4 1.7 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Abhydrolase_6 PF12697.7 KIY51666.1 - 4.8e-09 37.1 0.8 1.9e-08 35.2 0.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY51666.1 - 6e-08 32.6 0.1 2.2e-07 30.8 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold GRAM PF02893.20 KIY51667.1 - 0.00023 21.0 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KIY51667.1 - 0.077 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 KIY51667.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain adh_short_C2 PF13561.6 KIY51668.1 - 3.4e-58 197.0 0.4 4.3e-58 196.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51668.1 - 1.2e-48 165.1 0.4 1.6e-48 164.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51668.1 - 3.2e-14 53.2 0.2 4.6e-14 52.7 0.2 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIY51668.1 - 0.046 13.0 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 KIY51668.1 - 0.13 11.6 0.0 0.54 9.6 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Oxidored_FMN PF00724.20 KIY51669.1 - 1.4e-70 238.3 0.0 1.7e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 KIY51669.1 - 0.055 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ACPS PF01648.20 KIY51671.1 - 9.5e-15 54.7 0.0 9.6e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short_C2 PF13561.6 KIY51672.1 - 5.2e-52 176.7 1.3 6.1e-52 176.5 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51672.1 - 1.5e-45 155.1 0.7 1.9e-45 154.8 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51672.1 - 5e-14 52.6 1.6 7.3e-14 52.1 1.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY51672.1 - 0.0023 17.4 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Phage-tail_3 PF13550.6 KIY51672.1 - 0.015 15.2 0.0 0.067 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative phage tail protein PapA_C PF16911.5 KIY51672.1 - 0.018 15.1 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus DUF1776 PF08643.10 KIY51672.1 - 0.023 14.1 0.0 0.053 12.9 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KIY51672.1 - 0.042 13.2 0.0 0.065 12.5 0.0 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldedh PF00171.22 KIY51673.1 - 6.8e-103 344.6 0.0 8.2e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arb1 PF09692.10 KIY51674.1 - 2.4e-08 33.6 0.0 9.1e-08 31.7 0.0 1.8 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 WD40 PF00400.32 KIY51675.1 - 1.5e-27 95.3 10.5 0.00011 22.9 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY51675.1 - 4.7e-13 49.2 0.0 0.0036 17.6 0.0 5.0 3 3 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY51675.1 - 0.0004 20.3 0.0 0.2 11.5 0.0 3.1 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIY51675.1 - 0.00044 18.7 0.0 0.0063 14.9 0.0 2.1 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KIY51675.1 - 0.014 15.0 0.1 3.7 7.1 0.1 2.9 2 1 1 3 3 3 0 PQQ-like domain WD40_like PF17005.5 KIY51675.1 - 0.017 14.5 0.0 1.4 8.1 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 KIY51675.1 - 0.043 12.8 0.1 6.8 5.5 0.0 3.0 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RRP7 PF12923.7 KIY51676.1 - 1.3e-28 99.5 8.5 2e-28 98.9 8.5 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KIY51676.1 - 5.4e-11 42.6 0.2 2.2e-10 40.6 0.0 2.2 2 1 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KIY51676.1 - 0.00066 19.4 0.2 0.012 15.5 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5093 PF17011.5 KIY51676.1 - 0.057 13.7 0.0 0.057 13.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) E1_dh PF00676.20 KIY51677.1 - 2e-104 348.7 0.0 2.5e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KIY51677.1 - 1.1e-05 25.3 0.7 2.1e-05 24.4 0.7 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KIY51677.1 - 0.0043 16.3 0.0 0.0086 15.3 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DASH_Spc19 PF08287.11 KIY51678.1 - 2.5e-25 89.2 11.0 3.4e-25 88.8 9.9 1.7 1 1 1 2 2 2 1 Spc19 ALIX_LYPXL_bnd PF13949.6 KIY51678.1 - 0.0076 15.6 2.9 0.012 14.9 2.9 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MCM_N PF14551.6 KIY51678.1 - 0.064 13.9 1.4 0.11 13.1 1.3 1.4 1 1 0 1 1 1 0 MCM N-terminal domain DivIC PF04977.15 KIY51678.1 - 0.4 10.5 5.8 0.8 9.5 0.9 2.4 2 0 0 2 2 2 0 Septum formation initiator Fzo_mitofusin PF04799.13 KIY51678.1 - 0.46 10.0 5.0 3 7.4 0.8 2.2 2 0 0 2 2 2 0 fzo-like conserved region V_ATPase_I PF01496.19 KIY51678.1 - 0.62 7.9 2.5 0.55 8.1 1.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DHR10 PF18595.1 KIY51678.1 - 1.3 9.1 13.0 2.7 8.1 1.0 3.1 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Prefoldin_2 PF01920.20 KIY51678.1 - 1.7 8.6 11.0 6.2 6.8 2.3 2.5 2 1 0 2 2 2 0 Prefoldin subunit UPF0242 PF06785.11 KIY51678.1 - 3 7.9 10.0 23 5.0 10.1 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5595 PF18077.1 KIY51678.1 - 6.7 6.9 7.1 18 5.5 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) GDPD PF03009.17 KIY51679.1 - 6.3e-29 101.5 0.1 7.3e-28 98.0 0.1 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIY51679.1 - 0.00016 22.0 0.9 0.00036 20.9 0.9 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family NOA36 PF06524.12 KIY51681.1 - 0.44 9.8 7.7 0.68 9.2 7.7 1.2 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 KIY51681.1 - 0.97 9.0 11.6 1.6 8.3 11.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 KIY51681.1 - 9.3 4.3 6.5 13 3.8 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family GCP_N_terminal PF17681.1 KIY51683.1 - 8.6e-41 140.5 0.0 1.8e-40 139.5 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIY51683.1 - 4e-33 115.2 1.6 1.2e-32 113.6 1.3 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Mgm101p PF06420.12 KIY51685.1 - 1.7e-86 288.1 0.0 1.9e-86 287.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Peptidase_S10 PF00450.22 KIY51686.1 - 6.7e-97 325.5 0.0 8.4e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_gE PF02480.16 KIY51686.1 - 0.048 12.4 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Stevor PF17410.2 KIY51686.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Ribosomal_L5 PF00281.19 KIY51686.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L5 LPMO_10 PF03067.15 KIY51687.1 - 1.9e-12 48.3 0.1 2.6e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading VP4_2 PF08935.10 KIY51687.1 - 0.19 12.4 9.0 3 8.5 3.0 2.8 1 1 1 2 2 2 0 Viral protein VP4 subunit PAP_central PF04928.17 KIY51688.1 - 2.8e-112 373.7 0.0 3.7e-112 373.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KIY51688.1 - 4.9e-56 189.0 0.0 7.8e-56 188.4 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KIY51688.1 - 1.2e-11 44.7 0.0 4.2e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KIY51688.1 - 0.0024 17.6 0.1 0.0048 16.7 0.1 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain EVE PF01878.18 KIY51689.1 - 7.8e-38 129.7 0.0 9.8e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 EVE domain DUF3470 PF11953.8 KIY51689.1 - 0.092 12.7 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) MDH PF02315.16 KIY51689.1 - 0.46 10.6 5.4 1 9.4 5.2 1.7 1 1 0 1 1 1 0 Methanol dehydrogenase beta subunit Retrotrans_gag PF03732.17 KIY51691.1 - 2.5e-05 24.5 0.2 4.4e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein adh_short_C2 PF13561.6 KIY51693.1 - 1.7e-44 152.1 0.0 2.5e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51693.1 - 1e-41 142.5 0.0 1.8e-41 141.8 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51693.1 - 2.7e-05 24.2 0.0 3.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KIY51693.1 - 0.04 14.4 0.1 0.073 13.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KIY51693.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KIY51693.1 - 0.088 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KIY51693.1 - 0.12 12.2 0.4 0.2 11.5 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain APH PF01636.23 KIY51696.1 - 6e-19 68.9 2.0 1e-18 68.1 2.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY51696.1 - 0.00026 20.6 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KIY51696.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 KIY51696.1 - 0.14 11.8 0.0 0.96 9.0 0.0 2.0 2 0 0 2 2 2 0 RIO1 family zf-C2H2 PF00096.26 KIY51697.1 - 5.2e-06 26.6 10.0 0.01 16.2 1.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY51697.1 - 9.2e-06 25.9 2.0 9.2e-06 25.9 2.0 2.2 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY51697.1 - 0.00068 20.3 8.7 0.013 16.3 1.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIY51697.1 - 0.041 13.7 5.2 0.54 10.1 1.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KIY51697.1 - 0.15 12.1 1.0 0.15 12.1 1.0 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3841 PF12952.7 KIY51700.1 - 0.014 15.2 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) zinc_ribbon_5 PF13719.6 KIY51700.1 - 0.02 14.6 0.8 0.032 14.0 0.8 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Arylsulfotran_2 PF14269.6 KIY51701.1 - 5.9e-11 42.3 0.0 2.1e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY51701.1 - 0.14 11.0 0.0 0.77 8.6 0.0 2.1 1 1 1 2 2 2 0 Arylsulfotransferase (ASST) F-box-like PF12937.7 KIY51702.1 - 0.025 14.4 0.4 0.063 13.2 0.4 1.7 1 0 0 1 1 1 0 F-box-like SH2_2 PF14633.6 KIY51703.1 - 7.4e-48 162.8 0.1 8e-48 162.7 0.1 1.0 1 0 0 1 1 1 1 SH2 domain SH2 PF00017.24 KIY51703.1 - 1.3e-06 28.4 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 KIY51704.1 - 5.1e-16 58.9 0.1 9.2e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 KIY51704.1 - 5.4e-08 33.1 0.5 1e-07 32.1 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 KIY51704.1 - 5.2e-07 30.5 1.6 5.2e-06 27.3 1.6 2.4 1 1 0 1 1 1 1 HHH domain Transposase_21 PF02992.14 KIY51705.1 - 4.8e-08 32.5 0.2 9.2e-07 28.3 0.0 2.5 2 0 0 2 2 2 1 Transposase family tnp2 ATP_synt_H PF05493.13 KIY51706.1 - 4.8e-18 65.4 2.5 5.6e-18 65.2 2.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H TGBp3 PF02495.17 KIY51706.1 - 0.092 12.4 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Triple gene block 3 DnaJ-X PF14308.6 KIY51707.1 - 0.058 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing MM_CoA_mutase PF01642.22 KIY51707.1 - 0.086 11.4 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase CBP4 PF07960.11 KIY51707.1 - 0.12 12.2 0.7 0.27 11.1 0.7 1.5 1 0 0 1 1 1 0 CBP4 Retrotrans_gag PF03732.17 KIY51708.1 - 6.9e-05 23.0 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein NAD_binding_5 PF07994.12 KIY51708.1 - 0.023 14.1 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase ATP_synt_H PF05493.13 KIY51709.1 - 5.7e-19 68.3 4.6 7e-19 68.1 4.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Promethin PF16015.5 KIY51709.1 - 0.0057 16.6 5.7 0.0064 16.4 5.7 1.0 1 0 0 1 1 1 1 Promethin TGBp3 PF02495.17 KIY51709.1 - 0.029 14.0 0.5 0.037 13.7 0.5 1.2 1 0 0 1 1 1 0 Triple gene block 3 DUF4131 PF13567.6 KIY51709.1 - 0.16 11.6 2.2 0.16 11.6 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Methyltransf_23 PF13489.6 KIY51710.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KIY51710.1 - 0.088 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KIY51710.1 - 0.18 11.6 0.1 0.4 10.5 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain GMC_oxred_N PF00732.19 KIY51711.1 - 4.1e-58 197.1 0.0 6.1e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY51711.1 - 2.1e-28 99.7 0.0 3.6e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KIY51711.1 - 0.0012 18.2 0.1 1.1 8.4 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY51711.1 - 0.0023 17.1 0.1 0.0036 16.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein dUTPase PF00692.19 KIY51711.1 - 0.011 15.4 0.1 0.091 12.4 0.0 2.1 1 1 1 2 2 2 0 dUTPase NAD_binding_8 PF13450.6 KIY51711.1 - 0.094 13.0 0.1 0.39 11.0 0.1 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIY51711.1 - 0.15 11.2 0.1 0.46 9.7 0.1 1.8 2 0 0 2 2 2 0 Thi4 family PEX11 PF05648.14 KIY51712.1 - 1.3e-13 51.0 0.1 4.3e-13 49.3 0.1 1.7 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DNA_pol3_delta2 PF13177.6 KIY51713.1 - 4e-12 46.2 0.5 1e-11 44.9 0.5 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.13 KIY51713.1 - 2e-05 24.4 0.1 3.1e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KIY51713.1 - 3.7e-05 24.2 0.3 9.7e-05 22.8 0.3 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIY51713.1 - 0.00057 19.9 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Rep_fac_C PF08542.11 KIY51713.1 - 0.0031 17.9 0.0 0.0084 16.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_16 PF13191.6 KIY51713.1 - 0.011 16.1 0.1 0.039 14.3 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KIY51713.1 - 0.013 15.8 1.1 0.54 10.5 0.9 3.1 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIY51713.1 - 0.024 14.0 0.0 0.072 12.5 0.0 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KIY51713.1 - 0.09 12.5 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Pex26 PF07163.12 KIY51715.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Pex26 protein ADH_N PF08240.12 KIY51716.1 - 1.2e-22 79.9 2.6 1.8e-22 79.3 2.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY51716.1 - 9.4e-15 54.7 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY51716.1 - 1.7e-05 24.3 0.1 2.7e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY51716.1 - 0.00016 21.0 0.1 0.00031 20.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KIY51716.1 - 0.0068 16.6 0.0 0.016 15.4 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 KIY51716.1 - 0.019 15.8 0.0 0.47 11.3 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 KIY51716.1 - 0.031 14.2 0.2 0.045 13.6 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KIY51716.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 ThiF family WD40 PF00400.32 KIY51717.1 - 8.5e-23 80.2 22.2 5.4e-05 23.9 0.3 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 KIY51717.1 - 3.1e-06 26.2 5.3 0.14 10.8 0.0 3.8 2 2 2 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIY51717.1 - 2.3e-05 24.6 0.8 1.2 9.5 0.1 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KIY51717.1 - 0.00011 21.2 5.1 0.086 11.8 0.1 3.1 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 KIY51717.1 - 0.00046 20.6 5.7 4.7 7.8 0.1 5.4 6 0 0 6 6 6 2 PQQ-like domain PP2C_2 PF13672.6 KIY51717.1 - 0.0031 17.2 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C BBS2_Mid PF14783.6 KIY51717.1 - 0.0046 17.0 0.0 3.2 7.8 0.0 3.6 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 KIY51717.1 - 0.0057 16.3 3.7 0.061 12.9 3.7 2.5 1 1 0 1 1 1 1 PQQ-like domain Mcl1_mid PF12341.8 KIY51717.1 - 0.0067 15.8 0.2 0.11 11.9 0.1 2.4 1 1 2 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40_like PF17005.5 KIY51717.1 - 0.13 11.6 0.0 0.72 9.1 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain zf-rbx1 PF12678.7 KIY51717.1 - 0.15 12.4 1.1 0.95 9.8 0.0 2.6 3 0 0 3 3 3 0 RING-H2 zinc finger domain DUF4787 PF16029.5 KIY51718.1 - 0.061 13.4 0.9 0.085 13.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4787) Sad1_UNC PF07738.13 KIY51720.1 - 1.6e-24 86.4 0.0 1.4e-12 47.7 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal ABC_tran_CTD PF16326.5 KIY51720.1 - 0.33 11.2 3.6 0.63 10.3 1.8 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain Cut12 PF11500.8 KIY51720.1 - 2.3 8.2 12.8 2 8.4 0.1 3.6 3 2 1 4 4 4 0 Spindle pole body formation-associated protein RhoGAP PF00620.27 KIY51721.1 - 5.2e-35 120.5 0.0 8.1e-35 119.9 0.0 1.3 1 1 0 1 1 1 1 RhoGAP domain ORC_WH_C PF18137.1 KIY51721.1 - 0.072 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Mltc_N PF11873.8 KIY51721.1 - 0.083 12.6 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain Glyco_hydro_17 PF00332.18 KIY51722.1 - 2.6e-09 37.1 1.2 9.6e-09 35.2 0.6 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 17 Peptidase_S28 PF05577.12 KIY51723.1 - 1.1e-50 172.7 0.0 1.2e-40 139.6 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 GMC_oxred_N PF00732.19 KIY51724.1 - 1.2e-48 166.0 0.0 2.3e-23 83.0 0.0 2.5 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY51724.1 - 1.6e-37 129.2 0.0 2.4e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY51724.1 - 8.9e-06 25.9 0.0 3.7e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIY51724.1 - 1.9e-05 24.0 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KIY51724.1 - 2.9e-05 23.3 0.3 4.3e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIY51724.1 - 0.00025 20.7 1.0 0.0011 18.6 0.3 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY51724.1 - 0.00034 19.8 0.0 0.0038 16.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY51724.1 - 0.0025 17.1 0.0 0.038 13.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY51724.1 - 0.019 13.7 0.0 0.037 12.7 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KIY51724.1 - 0.17 11.1 0.2 0.25 10.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KIY51724.1 - 0.22 10.3 0.1 0.34 9.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Glyco_hydro_47 PF01532.20 KIY51725.1 - 2.7e-139 465.0 0.0 3.1e-139 464.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ank_4 PF13637.6 KIY51726.1 - 3.3e-22 78.6 3.3 0.0017 18.8 0.0 7.3 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY51726.1 - 7.9e-22 77.6 0.1 4.3e-08 33.6 0.0 4.9 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY51726.1 - 2e-17 63.0 6.1 0.00031 21.0 0.1 6.2 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY51726.1 - 8.4e-17 59.6 4.7 0.0058 17.0 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KIY51726.1 - 1.3e-13 50.7 2.7 0.086 13.3 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat HisKA_3 PF07730.13 KIY51726.1 - 0.088 13.3 3.6 0.24 12.0 0.1 3.2 3 0 0 3 3 3 0 Histidine kinase DUF883 PF05957.13 KIY51726.1 - 0.09 13.4 2.6 0.29 11.8 0.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) F-box-like PF12937.7 KIY51727.1 - 0.00097 19.0 0.5 0.00097 19.0 0.5 2.1 2 0 0 2 2 2 1 F-box-like Metallophos PF00149.28 KIY51729.1 - 3.5e-12 47.2 0.2 9.1e-12 45.9 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 KIY51729.1 - 0.013 13.8 1.8 0.04 12.2 0.0 2.2 3 0 0 3 3 3 0 Firmicute fructose-1,6-bisphosphatase eIF3_N PF09440.10 KIY51730.1 - 2.8e-47 160.5 3.4 5.9e-47 159.4 3.4 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KIY51730.1 - 1.7e-08 34.9 0.3 6.5e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 PCI domain TAP_C PF03943.13 KIY51733.1 - 1.1e-14 53.7 0.0 2.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 KIY51733.1 - 1.4e-07 31.2 0.1 2.5e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 KIY51733.1 - 2.8e-05 24.6 0.1 0.00059 20.4 0.1 2.4 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 KIY51733.1 - 0.023 14.5 6.2 0.098 12.4 5.7 2.3 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KIY51733.1 - 0.046 14.2 4.4 0.15 12.6 1.3 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Fungal_trans PF04082.18 KIY51734.1 - 8.9e-23 80.7 0.0 1.4e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY51734.1 - 6.3e-09 35.8 11.6 1.3e-08 34.8 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arginase PF00491.21 KIY51736.1 - 1.4e-42 146.1 0.7 2.5e-41 142.0 0.7 2.1 1 1 0 1 1 1 1 Arginase family DLH PF01738.18 KIY51737.1 - 0.033 13.7 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family E1-E2_ATPase PF00122.20 KIY51738.1 - 0.015 14.8 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 E1-E2 ATPase PEPcase_2 PF14010.6 KIY51738.1 - 0.08 11.4 0.3 0.12 10.9 0.3 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Phage_RpbA PF10789.9 KIY51739.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA DSPc PF00782.20 KIY51741.1 - 5.3e-24 84.5 0.0 7.7e-22 77.5 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY51741.1 - 0.0083 15.7 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4596 PF15363.6 KIY51742.1 - 0.079 13.2 2.5 0.079 13.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Ctf8 PF09696.10 KIY51743.1 - 2.4e-17 63.6 0.1 1.1e-14 55.0 0.1 2.1 1 1 0 1 1 1 1 Ctf8 Ribosomal_L13 PF00572.18 KIY51745.1 - 6.3e-51 171.9 0.0 8.2e-51 171.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 DLH PF01738.18 KIY51747.1 - 1.6e-11 44.2 0.0 1.9e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_M28 PF04389.17 KIY51748.1 - 3.7e-32 111.6 0.3 1.1e-31 110.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 GlcNAc_2-epim PF07221.11 KIY51748.1 - 0.008 15.5 0.2 0.018 14.3 0.1 1.5 2 0 0 2 2 2 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Peptidase_M20 PF01546.28 KIY51748.1 - 0.059 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 RRM_1 PF00076.22 KIY51749.1 - 8.6e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PD-C2-AF1 PF09310.10 KIY51751.1 - 0.0041 16.6 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 POU domain, class 2, associating factor 1 Fra10Ac1 PF09725.9 KIY51752.1 - 3e-45 153.3 0.6 3.3e-45 153.2 0.6 1.0 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Glyco_hydro_11 PF00457.17 KIY51752.1 - 0.07 12.8 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 Methyltransf_28 PF02636.17 KIY51753.1 - 1e-51 176.1 0.0 1.3e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase HLH PF00010.26 KIY51755.1 - 2.1e-10 40.4 0.6 4.3e-10 39.4 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tti2 PF10521.9 KIY51757.1 - 0.0048 16.5 0.1 0.009 15.6 0.1 1.4 1 0 0 1 1 1 1 Tti2 family MMS19_C PF12460.8 KIY51757.1 - 0.12 11.5 0.6 0.37 9.8 0.6 1.8 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Nop14 PF04147.12 KIY51758.1 - 0.11 10.7 5.8 0.17 10.1 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family IPP-2 PF04979.14 KIY51760.1 - 0.0099 16.6 3.3 0.0099 16.6 3.3 2.0 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) IPP-2 PF04979.14 KIY51761.1 - 0.0089 16.8 3.3 0.0089 16.8 3.3 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Coq4 PF05019.13 KIY51762.1 - 5.6e-95 316.9 0.0 7e-95 316.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 eIF-6 PF01912.18 KIY51763.1 - 2e-78 262.3 0.1 3.1e-78 261.7 0.0 1.3 2 0 0 2 2 2 1 eIF-6 family O-FucT PF10250.9 KIY51764.1 - 4e-09 36.6 0.0 5.2e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase adh_short_C2 PF13561.6 KIY51766.1 - 6.5e-18 65.1 0.2 1.4e-17 64.1 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51766.1 - 1.4e-12 47.5 0.2 2.4e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51766.1 - 0.0032 17.4 0.2 0.0047 16.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KIY51766.1 - 0.015 15.0 1.0 0.035 13.9 1.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-C2H2 PF00096.26 KIY51767.1 - 0.0018 18.6 10.0 0.0041 17.5 1.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY51767.1 - 0.0022 18.7 7.2 0.0032 18.2 0.5 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C3HC4 PF00097.25 KIY51767.1 - 0.44 10.4 1.6 4.3 7.3 0.0 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.7 KIY51768.1 - 3.5e-22 78.1 23.2 6.6e-06 26.4 1.8 8.4 6 2 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY51768.1 - 3.1e-19 68.5 17.5 6.5e-07 29.0 0.9 7.9 8 1 1 9 9 9 5 Leucine rich repeat LRR_1 PF00560.33 KIY51768.1 - 1e-06 28.5 20.7 1.6 9.6 0.0 9.9 11 1 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 KIY51768.1 - 2.7e-06 27.0 21.9 0.6 10.3 0.1 8.3 10 0 0 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.6 KIY51768.1 - 0.16 11.5 3.2 1.3 8.5 1.0 3.1 3 0 0 3 3 3 0 Leucine-rich repeat DFRP_C PF16543.5 KIY51769.1 - 4.3e-30 104.0 5.5 4.3e-30 104.0 5.5 4.0 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KIY51769.1 - 8.4e-07 28.7 6.9 3.6e-05 23.4 1.5 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIY51769.1 - 1.4e-06 28.1 17.4 0.00015 21.7 6.8 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KIY51769.1 - 1.9e-06 27.6 0.8 1.9e-06 27.6 0.8 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY51769.1 - 3.1e-06 27.8 14.8 0.00098 19.8 3.2 4.0 2 2 1 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 KIY51769.1 - 0.0044 17.4 7.0 0.39 11.3 2.5 2.6 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KIY51769.1 - 0.016 15.4 3.9 0.92 9.7 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger containing family DUF1115 PF06544.12 KIY51770.1 - 0.00027 21.1 0.0 0.00036 20.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) PLDc_2 PF13091.6 KIY51771.1 - 3.1e-11 43.3 0.0 0.00012 22.0 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KIY51771.1 - 7.7e-06 25.9 0.8 0.14 12.4 0.0 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif ABC_membrane PF00664.23 KIY51772.1 - 1.2e-39 136.6 11.8 1.5e-39 136.3 11.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIY51772.1 - 1.2e-32 113.3 0.0 2.5e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY51772.1 - 2e-06 27.4 0.0 0.00019 20.9 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY51772.1 - 9.6e-06 25.6 0.0 0.03 14.1 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY51772.1 - 0.0079 16.6 0.0 0.025 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY51772.1 - 0.0097 16.2 0.0 0.036 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIY51772.1 - 0.013 15.9 0.1 0.23 11.9 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KIY51772.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KIY51772.1 - 0.034 13.9 0.0 0.098 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KIY51772.1 - 0.035 14.0 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 KIY51772.1 - 0.05 13.6 0.0 0.24 11.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KIY51772.1 - 0.072 13.0 0.0 0.33 10.9 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 KIY51772.1 - 0.09 12.9 0.0 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1524 PF07510.11 KIY51772.1 - 0.1 12.5 0.6 0.85 9.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) MMR_HSR1 PF01926.23 KIY51772.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KIY51772.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIY51772.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIY51772.1 - 0.16 12.0 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIY51772.1 - 0.18 12.3 0.0 0.5 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain Torus PF16131.5 KIY51773.1 - 3.1e-38 130.8 0.9 4.7e-38 130.2 0.9 1.3 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KIY51773.1 - 1.9e-05 24.4 0.0 4.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIY51773.1 - 0.00013 21.9 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 KIY51773.1 - 0.14 12.3 5.4 0.28 11.3 5.4 1.6 1 0 0 1 1 1 0 Zinc finger domain FA_desaturase PF00487.24 KIY51777.1 - 3.2e-23 82.9 25.1 5.4e-23 82.1 25.1 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIY51777.1 - 2.3e-05 24.6 0.0 4.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.24 KIY51778.1 - 3.5e-28 99.1 24.2 3.5e-28 99.1 24.2 1.5 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 KIY51778.1 - 6.2e-07 29.7 0.1 1.1e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) MRP-L27 PF09809.9 KIY51779.1 - 1.3e-08 34.7 0.1 1.7e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Med22 PF06179.12 KIY51780.1 - 1.3e-18 67.1 0.8 2e-18 66.6 0.8 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PMC2NT PF08066.12 KIY51780.1 - 0.012 16.3 1.7 0.26 12.0 0.1 2.3 1 1 0 2 2 2 0 PMC2NT (NUC016) domain zf-H2C2_2 PF13465.6 KIY51783.1 - 5.6e-09 36.0 3.4 3.7e-07 30.3 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-met PF12874.7 KIY51783.1 - 1.5e-06 28.4 2.5 0.07 13.5 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KIY51783.1 - 1.7e-06 28.1 7.3 0.001 19.4 2.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY51783.1 - 9.4e-06 26.1 9.3 0.0011 19.7 2.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY51783.1 - 0.00041 20.5 2.7 1.6 9.1 3.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIY51783.1 - 0.015 15.5 1.0 0.028 14.7 1.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KIY51783.1 - 0.019 14.7 1.4 0.048 13.4 1.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Elf1 PF05129.13 KIY51783.1 - 0.019 15.0 1.7 0.039 14.0 1.7 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 KIY51783.1 - 0.041 13.7 2.4 2.2 8.1 0.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KIY51783.1 - 0.081 13.6 2.6 1.7 9.3 0.3 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 KIY51783.1 - 0.28 11.4 4.9 0.61 10.3 0.9 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger MFS_1 PF07690.16 KIY51784.1 - 2.5e-50 171.4 52.2 7.1e-47 160.0 54.0 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY51784.1 - 2.2e-12 46.2 18.4 2.2e-12 46.2 18.4 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIY51784.1 - 2.3e-10 39.9 32.4 1.3e-09 37.5 14.4 2.7 2 0 0 2 2 2 2 Sugar (and other) transporter zf-RING_5 PF14634.6 KIY51785.1 - 0.094 12.7 8.5 0.14 12.1 8.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain LysM PF01476.20 KIY51786.1 - 8.4e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 LysM domain adh_short PF00106.25 KIY51787.1 - 8.7e-88 292.9 16.2 7.3e-45 152.8 3.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY51787.1 - 1.6e-71 240.5 16.7 8.5e-36 123.7 2.1 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY51787.1 - 1.3e-30 106.7 9.6 1.4e-15 57.6 1.2 2.2 2 0 0 2 2 2 2 KR domain 3HCDH_N PF02737.18 KIY51787.1 - 2.5e-05 24.2 9.4 0.0026 17.7 1.4 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIY51787.1 - 0.00021 20.7 0.5 0.28 10.5 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KIY51787.1 - 0.00037 19.8 1.0 0.21 10.9 0.2 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CstA_5TM PF13722.6 KIY51787.1 - 0.012 16.0 0.8 0.59 10.5 0.1 2.8 2 1 0 2 2 2 0 5TM C-terminal transporter carbon starvation CstA Phage_portal_2 PF05136.13 KIY51787.1 - 0.013 14.7 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Phage portal protein, lambda family CoA_binding PF02629.19 KIY51787.1 - 0.089 13.5 2.6 3.5 8.4 0.1 3.1 3 0 0 3 3 2 0 CoA binding domain Ldh_1_N PF00056.23 KIY51787.1 - 0.34 11.0 5.8 1.1 9.3 0.6 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KIY51787.1 - 0.49 10.0 2.8 10 5.7 0.2 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglL_A PF15864.5 KIY51787.1 - 0.98 9.2 8.2 7.1 6.5 1.1 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase DUF543 PF04418.12 KIY51787.1 - 1.9 8.5 10.9 3.7 7.6 0.4 3.5 4 0 0 4 4 3 0 Domain of unknown function (DUF543) Rit1_C PF17184.4 KIY51789.1 - 6.4e-94 314.4 0.0 8e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KIY51789.1 - 2.1e-18 66.6 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Glyco_trans_1_3 PF13528.6 KIY51790.1 - 0.0041 16.4 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 RlaP PF10127.9 KIY51791.1 - 0.054 13.1 0.1 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 RNA repair pathway DNA polymerase beta family DUF2396 PF09654.10 KIY51791.1 - 0.088 12.9 0.5 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) PP1_bind PF15276.6 KIY51791.1 - 0.11 12.8 2.0 0.18 12.2 0.1 2.3 2 0 0 2 2 2 0 Protein phosphatase 1 binding Y_phosphatase PF00102.27 KIY51792.1 - 8.8e-41 140.0 0.0 8.3e-28 97.5 0.0 3.1 3 1 0 3 3 3 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIY51792.1 - 0.0012 19.0 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KIY51792.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DivIVA PF05103.13 KIY51793.1 - 0.0033 17.5 3.1 0.0033 17.5 3.1 2.1 2 1 0 2 2 2 1 DivIVA protein DUF745 PF05335.13 KIY51793.1 - 0.014 15.1 6.1 0.022 14.5 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF883 PF05957.13 KIY51793.1 - 0.032 14.8 3.5 0.17 12.5 1.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HisKA_3 PF07730.13 KIY51793.1 - 0.034 14.6 4.3 0.28 11.7 0.2 2.7 2 1 1 3 3 3 0 Histidine kinase BRE1 PF08647.11 KIY51793.1 - 0.039 14.0 1.6 0.62 10.2 0.0 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Vir_act_alpha_C PF10400.9 KIY51793.1 - 0.075 13.7 4.9 0.7 10.6 0.7 2.9 1 1 2 3 3 3 0 Virulence activator alpha C-term TipAS PF07739.13 KIY51793.1 - 0.13 12.8 2.9 2 9.0 0.3 2.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Actin PF00022.19 KIY51794.1 - 1.6e-38 132.4 0.0 2.9e-31 108.5 0.0 3.4 3 1 0 3 3 3 3 Actin Methyltransf_16 PF10294.9 KIY51795.1 - 1.2e-13 51.2 0.0 2.7e-13 50.0 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KIY51795.1 - 0.17 11.9 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Mito_carr PF00153.27 KIY51796.1 - 1.3e-57 191.7 1.7 1.1e-21 76.5 0.7 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Arrestin_N PF00339.29 KIY51797.1 - 0.0053 16.8 0.0 0.07 13.2 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain ABC_tran PF00005.27 KIY51798.1 - 9.4e-49 165.4 0.0 5.6e-25 88.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY51798.1 - 3.8e-44 151.4 30.6 2.4e-26 93.0 9.2 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY51798.1 - 7.8e-10 38.6 4.0 0.0058 16.1 0.1 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY51798.1 - 1.2e-06 29.1 0.0 0.032 14.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KIY51798.1 - 7.8e-06 26.0 3.0 0.058 13.5 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIY51798.1 - 1.1e-05 25.0 1.8 0.061 13.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY51798.1 - 1.3e-05 25.2 6.6 0.17 11.7 0.1 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIY51798.1 - 1.8e-05 24.7 1.1 0.0076 16.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 KIY51798.1 - 0.00041 19.6 0.7 0.26 10.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KIY51798.1 - 0.00091 18.6 0.4 0.88 8.9 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.6 KIY51798.1 - 0.0019 18.7 0.5 3 8.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KIY51798.1 - 0.0035 17.3 0.9 0.28 11.1 0.1 2.7 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 KIY51798.1 - 0.0039 17.4 0.4 2.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KIY51798.1 - 0.0048 16.2 1.1 0.64 9.3 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.14 KIY51798.1 - 0.0055 16.6 2.3 0.34 10.8 0.2 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 KIY51798.1 - 0.0078 15.7 0.6 4.2 6.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 KIY51798.1 - 0.0094 15.9 0.8 1.1 9.3 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 KIY51798.1 - 0.0097 14.9 2.3 0.85 8.5 0.2 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 KIY51798.1 - 0.011 15.8 4.9 0.35 10.9 0.7 2.5 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 KIY51798.1 - 0.013 15.2 0.4 2.2 8.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KIY51798.1 - 0.023 14.4 0.1 2.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KIY51798.1 - 0.026 14.7 2.1 37 4.5 0.2 3.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KIY51798.1 - 0.03 14.7 0.1 14 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 KIY51798.1 - 0.031 14.4 4.2 0.27 11.3 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 KIY51798.1 - 0.045 14.0 5.0 6 7.1 0.6 3.2 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 KIY51798.1 - 0.058 12.4 3.6 1.8 7.5 0.5 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 KIY51798.1 - 0.066 12.4 0.2 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 KAP family P-loop domain T2SSE PF00437.20 KIY51798.1 - 0.07 12.2 2.0 1.2 8.2 0.1 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein NB-ARC PF00931.22 KIY51798.1 - 0.098 11.8 0.7 8.3 5.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 KIY51798.1 - 0.12 11.9 0.8 8 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KIY51798.1 - 0.15 11.8 0.4 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KIY51798.1 - 0.16 12.5 2.6 3.9 8.0 0.0 3.3 4 0 0 4 4 2 0 AAA domain ATP_bind_1 PF03029.17 KIY51798.1 - 0.21 11.4 1.4 7.8 6.2 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KIY51798.1 - 0.4 10.2 3.1 1.9 8.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PHD PF00628.29 KIY51799.1 - 9.2e-11 41.5 2.4 9.2e-11 41.5 2.4 2.0 1 1 1 2 2 2 1 PHD-finger Zf_RING PF16744.5 KIY51799.1 - 0.0098 16.0 0.7 0.0098 16.0 0.7 2.0 1 1 1 2 2 2 1 KIAA1045 RING finger C1_2 PF03107.16 KIY51799.1 - 0.012 15.9 10.8 0.02 15.2 10.8 1.4 1 1 0 1 1 1 0 C1 domain Prok-RING_1 PF14446.6 KIY51799.1 - 0.065 13.2 8.3 0.091 12.7 8.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KIY51799.1 - 0.091 12.3 7.7 0.11 12.1 0.0 2.6 2 1 1 3 3 3 0 PHD-finger MOZ_SAS PF01853.18 KIY51800.1 - 3.3e-66 222.3 0.1 4.4e-66 221.9 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KIY51800.1 - 1.3e-18 66.3 2.1 2.2e-18 65.6 0.4 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 KIY51800.1 - 0.036 14.1 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF4106 PF13388.6 KIY51801.1 - 5.8 6.1 8.1 11 5.1 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SF1-HH PF16275.5 KIY51802.1 - 4.5e-40 136.5 1.6 1.1e-39 135.3 1.6 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KIY51802.1 - 1.1e-11 44.2 8.9 1.4e-05 24.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KIY51802.1 - 8.9e-07 28.8 4.1 0.0028 17.6 1.5 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KIY51802.1 - 2.5e-05 24.0 0.0 5.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.6 KIY51802.1 - 0.0026 17.6 5.3 0.54 10.1 0.9 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KIY51802.1 - 0.0059 16.3 7.1 0.41 10.4 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle CCDC-167 PF15188.6 KIY51802.1 - 0.0066 16.8 2.1 3.3 8.1 0.1 2.4 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 DnaJ_CXXCXGXG PF00684.19 KIY51802.1 - 0.18 12.2 4.8 0.47 10.9 4.8 1.6 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.6 KIY51802.1 - 3.8 7.4 9.8 0.36 10.7 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle 6PF2K PF01591.18 KIY51803.1 - 3.4e-70 235.8 0.1 5e-70 235.3 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KIY51803.1 - 4.8e-35 121.0 0.0 8.8e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KIY51803.1 - 3.7e-06 27.2 0.0 7.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KIY51803.1 - 0.0028 17.1 0.0 0.0055 16.2 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Methyltr_RsmB-F PF01189.17 KIY51805.1 - 8.6e-27 94.1 0.0 1.5e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 KIY51805.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_31 PF13847.6 KIY51805.1 - 0.056 13.2 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DnaJ_C PF01556.18 KIY51806.1 - 9.4e-35 119.9 0.1 1.3e-34 119.4 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY51806.1 - 1.8e-20 72.8 0.2 3.4e-20 71.9 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIY51806.1 - 2.9e-13 50.0 18.1 4.8e-13 49.3 18.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KIY51806.1 - 4.5e-05 23.3 11.3 0.01 15.8 2.4 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KIY51806.1 - 0.0049 16.9 9.4 0.23 11.5 2.5 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3295 PF11702.8 KIY51806.1 - 0.61 9.4 2.1 0.88 8.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) ThuA PF06283.11 KIY51807.1 - 1.4e-36 126.7 0.6 3.9e-35 122.0 0.6 2.4 1 1 0 1 1 1 1 Trehalose utilisation DUF3808 PF10300.9 KIY51809.1 - 0.026 13.3 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) AhpC-TSA_2 PF13911.6 KIY51810.1 - 0.0026 17.9 0.0 0.0056 16.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Pkinase PF00069.25 KIY51811.1 - 9.3e-27 94.0 0.0 1.1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51811.1 - 1.6e-12 47.3 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY51811.1 - 1.5e-08 33.8 0.0 1.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY51811.1 - 0.00045 20.2 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Mitofilin PF09731.9 KIY51812.1 - 2.7e-106 356.9 23.0 9.6e-106 355.0 23.0 1.7 1 1 0 1 1 1 1 Mitochondrial inner membrane protein BssS PF13991.6 KIY51812.1 - 0.28 11.3 1.8 0.56 10.3 0.5 2.2 2 0 0 2 2 2 0 BssS protein family Exonuc_VII_L PF02601.15 KIY51812.1 - 1.7 8.1 19.3 0.15 11.6 4.1 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit RAB3GAP2_N PF14655.6 KIY51813.1 - 0.014 14.7 0.2 0.017 14.4 0.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DEAD PF00270.29 KIY51814.1 - 4.5e-39 134.0 0.0 1.7e-38 132.1 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY51814.1 - 4.1e-24 85.1 0.2 7.7e-22 77.7 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY51814.1 - 2.4e-09 37.4 0.0 5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIY51814.1 - 0.022 15.1 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY51814.1 - 0.08 13.2 0.9 2.1 8.6 1.0 2.7 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KIY51814.1 - 0.12 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain F-box-like PF12937.7 KIY51815.1 - 0.057 13.3 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 F-box-like EF1G PF00647.19 KIY51815.1 - 0.06 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Phospholamban PF04272.14 KIY51815.1 - 0.097 12.2 0.6 0.21 11.1 0.6 1.6 1 0 0 1 1 1 0 Phospholamban Mto2_bdg PF12808.7 KIY51815.1 - 0.15 12.4 0.1 0.37 11.1 0.1 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Tht1 PF04163.12 KIY51816.1 - 4.3e-09 35.7 0.1 6e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein AA_permease_2 PF13520.6 KIY51817.1 - 5.1e-62 210.1 52.4 6.3e-62 209.8 52.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY51817.1 - 9.6e-13 47.5 44.7 1.4e-12 47.0 44.7 1.2 1 0 0 1 1 1 1 Amino acid permease Phage_holin_2_4 PF16082.5 KIY51817.1 - 0.6 9.9 2.7 1.7 8.4 1.4 2.5 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Frag1 PF10277.9 KIY51818.1 - 7.1e-40 136.9 17.4 8.3e-40 136.7 17.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KIY51818.1 - 0.00036 20.2 10.7 0.00079 19.1 10.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF998) PgaD PF13994.6 KIY51818.1 - 4.5 7.3 12.4 14 5.7 2.1 3.3 2 1 1 3 3 3 0 PgaD-like protein ATP-synt_G PF04718.15 KIY51819.1 - 1.8e-17 64.0 0.3 9.7e-17 61.6 0.0 2.0 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit Apo-CII PF05355.11 KIY51819.1 - 0.084 13.0 3.2 1 9.5 0.2 2.9 2 1 1 3 3 3 0 Apolipoprotein C-II zf-C2H2 PF00096.26 KIY51821.1 - 9.6e-13 47.8 16.2 2.5e-05 24.5 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY51821.1 - 8.2e-09 35.5 18.1 2.6e-05 24.4 0.6 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY51821.1 - 2.8e-08 33.9 15.2 0.0051 17.5 0.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIY51821.1 - 0.00083 19.3 12.2 0.0092 16.0 0.8 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIY51821.1 - 0.05 13.7 6.6 2.3 8.4 0.1 3.1 1 1 2 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 KIY51821.1 - 1.4 9.5 11.3 9.8 6.7 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY51821.1 - 3.1 8.2 10.3 6.7 7.1 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding LRR_4 PF12799.7 KIY51822.1 - 0.021 15.3 0.8 3.1 8.4 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY51822.1 - 0.2 11.4 0.0 69 3.3 0.0 3.4 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.7 KIY51822.1 - 0.21 11.5 1.9 0.53 10.2 1.9 1.7 1 0 0 1 1 1 0 F-box-like HMGL-like PF00682.19 KIY51823.1 - 9.8e-79 264.6 0.2 1.4e-78 264.1 0.2 1.3 1 0 0 1 1 1 1 HMGL-like T3SSipB PF16535.5 KIY51823.1 - 0.047 14.2 0.0 0.094 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB FliG_N PF14842.6 KIY51823.1 - 0.14 12.7 0.1 0.28 11.7 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain LapA_dom PF06305.11 KIY51824.1 - 0.43 10.4 0.0 0.43 10.4 0.0 3.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Helitron_like_N PF14214.6 KIY51825.1 - 3.2e-39 135.1 0.0 5.9e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Clr2_transil PF16761.5 KIY51828.1 - 3.5e-21 75.8 0.4 9.3e-21 74.4 0.4 1.8 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KIY51828.1 - 1.3e-13 52.0 0.0 4e-13 50.4 0.0 1.9 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 zf-HIT PF04438.16 KIY51829.1 - 4.4e-07 29.6 14.7 6.4e-07 29.1 14.7 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KIY51829.1 - 0.055 13.6 9.5 0.09 12.9 9.5 1.3 1 0 0 1 1 1 0 MYND finger Tnp_zf-ribbon_2 PF13842.6 KIY51829.1 - 6.3 7.7 14.0 11 7.0 14.0 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon RED_N PF07808.13 KIY51830.1 - 3.5e-17 62.8 2.6 3.5e-17 62.8 2.6 2.6 3 0 0 3 3 3 1 RED-like protein N-terminal region Carb_kinase PF01256.17 KIY51831.1 - 9e-49 166.1 0.0 1.4e-48 165.5 0.0 1.3 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KIY51831.1 - 0.0043 16.5 0.0 0.0099 15.3 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase RNA_pol_Rpb6 PF01192.22 KIY51831.1 - 0.089 12.7 0.7 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb6 Cation_efflux PF01545.21 KIY51832.1 - 1.6e-37 129.2 14.5 2.5e-37 128.5 14.5 1.3 1 0 0 1 1 1 1 Cation efflux family Transport_MerF PF11431.8 KIY51832.1 - 0.059 13.3 1.4 0.2 11.6 1.4 2.0 1 0 0 1 1 1 0 Membrane transport protein MerF PAP2 PF01569.21 KIY51832.1 - 0.31 10.8 4.3 18 5.1 0.0 3.4 2 1 1 3 3 3 0 PAP2 superfamily SPOC PF07744.13 KIY51833.1 - 4.8e-11 42.8 0.0 6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KIY51834.1 - 1.9e-20 73.4 0.2 2.2e-20 73.2 0.2 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Pkinase PF00069.25 KIY51836.1 - 3.3e-71 239.7 0.0 6.8e-71 238.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51836.1 - 1.7e-53 181.5 0.0 2e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY51836.1 - 0.002 17.5 0.4 0.11 11.9 0.1 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY51836.1 - 0.0026 17.1 0.0 0.01 15.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KIY51836.1 - 0.01 15.5 0.0 0.024 14.2 0.0 1.6 1 1 1 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KIY51836.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KIY51836.1 - 0.023 13.8 0.1 0.046 12.8 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 KIY51836.1 - 0.043 13.3 0.1 0.07 12.6 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PIP49_C PF12260.8 KIY51836.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein-kinase domain of FAM69 DUF1195 PF06708.11 KIY51837.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Melibiase_2 PF16499.5 KIY51838.1 - 1.1e-54 185.5 6.5 6.4e-53 179.8 6.5 2.3 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIY51838.1 - 2.4e-12 46.7 0.4 6.1e-12 45.4 0.4 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIY51838.1 - 3.7e-05 22.8 0.0 5.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Melibiase PDZ_2 PF13180.6 KIY51838.1 - 0.059 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Malt_amylase_C PF16657.5 KIY51838.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain zf-met PF12874.7 KIY51839.1 - 3.8e-16 58.9 8.8 5.6e-05 23.4 0.1 5.0 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY51839.1 - 1.1e-06 28.8 20.8 0.044 14.1 0.3 5.5 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY51839.1 - 0.0047 17.7 22.4 0.26 12.2 0.2 5.9 6 0 0 6 6 6 2 C2H2-type zinc finger Pro_3_hydrox_C PF05373.11 KIY51839.1 - 0.057 13.5 0.2 0.098 12.7 0.2 1.3 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal SPX PF03105.19 KIY51839.1 - 0.92 9.3 6.7 1.8 8.4 6.6 1.7 1 1 0 1 1 1 0 SPX domain zf-C2H2 PF00096.26 KIY51839.1 - 1.1 9.8 12.2 4.9 7.8 0.1 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF4451 PF14616.6 KIY51840.1 - 0.025 14.8 2.7 0.39 10.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4451) SAP PF02037.27 KIY51841.1 - 0.0002 21.0 1.6 0.00027 20.6 0.1 2.1 2 0 0 2 2 2 1 SAP domain FeS_assembly_P PF01883.19 KIY51842.1 - 1.3e-09 38.1 0.3 2.1e-09 37.4 0.0 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein DUF4674 PF15719.5 KIY51843.1 - 0.051 13.6 1.7 0.096 12.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) WD40 PF00400.32 KIY51844.1 - 8.8e-23 80.2 16.7 0.0015 19.3 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY51844.1 - 0.00026 21.2 0.2 0.93 9.8 0.1 3.9 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY51844.1 - 0.0018 17.3 0.2 0.04 12.9 0.0 2.8 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4524 PF15025.6 KIY51844.1 - 0.053 13.3 0.3 3.7 7.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) SIR2 PF02146.17 KIY51845.1 - 1.6e-33 116.1 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family DUF364 PF04016.12 KIY51845.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation Vps5 PF09325.10 KIY51846.1 - 3.9e-67 226.3 5.0 5.3e-67 225.8 5.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KIY51846.1 - 4e-29 100.9 0.4 2.8e-27 94.9 0.0 2.4 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 KIY51846.1 - 2.1e-05 24.1 2.8 0.00032 20.2 2.6 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_3 PF16746.5 KIY51846.1 - 0.00025 20.9 1.2 0.0012 18.6 0.1 2.0 1 1 0 2 2 2 1 BAR domain of APPL family Staph_opine_DH PF10100.9 KIY51846.1 - 0.0075 15.0 0.5 0.011 14.4 0.5 1.2 1 0 0 1 1 1 1 Staphylopine dehydrogenase Lipase_GDSL PF00657.22 KIY51846.1 - 0.031 14.3 0.0 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Arfaptin PF06456.13 KIY51846.1 - 0.096 12.2 3.6 2 7.9 3.6 2.2 1 1 0 1 1 1 0 Arfaptin-like domain MscS_porin PF12795.7 KIY51846.1 - 0.33 10.5 7.8 0.16 11.5 4.3 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain WD40 PF00400.32 KIY51847.1 - 9.5e-10 38.9 4.2 0.7 10.9 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3770 PF12603.8 KIY51847.1 - 0.044 13.3 1.1 0.2 11.2 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3770) Carm_PH PF17888.1 KIY51847.1 - 0.14 12.5 0.1 8.8 6.8 0.0 2.5 1 1 1 2 2 2 0 Carmil pleckstrin homology domain Dsl1_C PF11989.8 KIY51849.1 - 2.8e-12 46.8 0.1 6.5e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.13 KIY51849.1 - 1.6e-06 27.0 0.3 1.4e-05 23.9 0.7 2.3 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 ABC_tran_CTD PF16326.5 KIY51849.1 - 0.00089 19.5 2.2 0.0014 18.8 0.0 2.6 3 0 0 3 3 3 1 ABC transporter C-terminal domain ApoLp-III PF07464.11 KIY51849.1 - 0.018 15.2 0.8 0.35 11.0 0.3 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CinA_KH PF18146.1 KIY51849.1 - 0.057 13.6 1.0 1.1 9.5 0.1 2.7 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Fib_alpha PF08702.10 KIY51849.1 - 0.067 13.4 0.4 0.37 11.0 0.1 2.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.12 KIY51849.1 - 0.12 12.5 3.7 5.4 7.2 0.1 3.7 3 0 0 3 3 3 0 MbeD/MobD like Arg_decarbox_C PF17944.1 KIY51849.1 - 0.27 11.8 0.8 9 6.9 0.0 3.4 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension COG5 PF10392.9 KIY51849.1 - 0.36 11.0 3.8 0.22 11.7 1.2 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 MMgT PF10270.9 KIY51850.1 - 3.8e-13 49.6 0.0 4.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter NCE101 PF11654.8 KIY51850.1 - 1.1 9.0 4.1 13 5.6 0.5 2.3 1 1 1 2 2 2 0 Non-classical export protein 1 DUF4502 PF14950.6 KIY51851.1 - 1.3e-06 28.2 0.1 2e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) TRI5 PF06330.11 KIY51852.1 - 3.9e-16 58.9 0.0 5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) PALP PF00291.25 KIY51853.1 - 2.7e-53 181.3 0.5 3.1e-53 181.1 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DOPA_dioxygen PF08883.11 KIY51854.1 - 1.7e-45 153.6 0.2 2.1e-45 153.3 0.2 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Questin_oxidase PF14027.6 KIY51855.1 - 1.2e-81 274.9 0.0 1.4e-81 274.7 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like eIF2A PF08662.11 KIY51856.1 - 8.5e-80 267.2 0.0 2.3e-79 265.8 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KIY51856.1 - 0.0043 17.9 0.3 1.5 9.8 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.6 KIY51856.1 - 0.035 14.6 2.4 0.04 14.4 1.0 1.8 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 Proteasome_A_N PF10584.9 KIY51856.1 - 0.51 10.1 2.0 27 4.6 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 KIY51856.1 - 5.7 7.0 5.6 69 3.5 0.1 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat E1-E2_ATPase PF00122.20 KIY51857.1 - 6.1e-49 166.0 2.6 1.4e-48 164.8 2.6 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KIY51857.1 - 1.2e-34 120.4 0.2 2.9e-34 119.2 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIY51857.1 - 1.6e-32 111.7 0.1 7.4e-15 55.2 0.0 2.8 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KIY51857.1 - 3.7e-05 23.6 0.2 0.012 15.4 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 KIY51857.1 - 0.035 14.1 2.9 1.6 8.8 0.6 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Otopetrin PF03189.13 KIY51857.1 - 0.081 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Otopetrin Glutaredoxin PF00462.24 KIY51858.1 - 4.4e-16 58.8 0.1 7.4e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KIY51858.1 - 0.0021 18.5 0.2 0.0059 17.0 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KIY51858.1 - 0.0036 17.7 0.1 0.0057 17.0 0.1 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Dynactin_p22 PF07426.11 KIY51859.1 - 2.8e-17 63.1 0.0 3.8e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Orexin PF02072.15 KIY51859.1 - 0.0046 16.9 0.0 0.0099 15.8 0.0 1.5 2 0 0 2 2 2 1 Prepro-orexin Lebercilin PF15619.6 KIY51859.1 - 0.014 15.1 5.6 0.025 14.2 4.4 2.0 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CHASE3 PF05227.13 KIY51859.1 - 1.2 9.0 9.5 0.35 10.8 2.3 2.5 2 1 0 2 2 2 0 CHASE3 domain F-box-like PF12937.7 KIY51860.1 - 1.5e-07 31.2 1.2 1.5e-07 31.2 1.2 3.1 3 1 0 3 3 3 1 F-box-like Pinin_SDK_N PF04697.13 KIY51860.1 - 0.1 13.3 0.4 0.18 12.4 0.4 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region F-box PF00646.33 KIY51860.1 - 0.24 11.3 4.7 1.1 9.2 1.7 3.2 3 1 0 3 3 3 0 F-box domain SKN1 PF03935.15 KIY51861.1 - 5.6e-65 219.7 0.0 6.6e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) F-box-like PF12937.7 KIY51862.1 - 2.1e-09 37.1 0.2 1.2e-08 34.7 0.2 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY51862.1 - 0.0028 17.5 6.7 0.26 11.2 1.8 4.1 3 1 0 3 3 3 2 F-box domain Plavaka PF18759.1 KIY51865.1 - 8.7e-25 87.6 0.1 2.9e-24 85.9 0.1 1.8 1 1 0 1 1 1 1 Plavaka transposase DUF4048 PF13257.6 KIY51867.1 - 0.037 13.9 1.1 0.054 13.3 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) Carn_acyltransf PF00755.20 KIY51868.1 - 4.3e-173 577.1 0.0 4.8e-173 576.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase 5_3_exonuc_N PF02739.16 KIY51869.1 - 0.053 13.4 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain VPS28 PF03997.12 KIY51870.1 - 5.3e-72 241.5 0.1 6.1e-72 241.3 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Thioredoxin PF00085.20 KIY51871.1 - 6.1e-16 58.3 0.0 1.8e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 KIY51871.1 - 0.0056 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KIY51871.1 - 0.046 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 KIY51871.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KIY51871.1 - 0.15 11.9 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 KIY51871.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like DnaJ PF00226.31 KIY51872.1 - 2.2e-15 56.5 1.0 5.3e-15 55.3 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain Ran_BP1 PF00638.18 KIY51874.1 - 2.8e-05 24.4 0.0 4.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain SPX PF03105.19 KIY51874.1 - 1.5 8.7 12.1 2 8.3 12.1 1.3 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 KIY51874.1 - 6.3 5.4 8.8 7.5 5.1 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BCS1_N PF08740.11 KIY51875.1 - 6.5e-44 150.2 1.5 6.5e-44 150.2 1.5 2.1 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KIY51875.1 - 1.3e-14 54.8 0.0 4e-13 49.9 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY51875.1 - 0.0013 19.1 2.4 0.0027 18.1 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KIY51875.1 - 0.0043 17.2 0.0 0.0043 17.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 KIY51875.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KIY51875.1 - 0.007 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 KIY51875.1 - 0.04 13.1 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 KIY51875.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 KIY51875.1 - 0.051 14.1 2.3 3.5 8.1 2.0 2.4 2 0 0 2 2 2 0 AAA domain DUF1570 PF07607.11 KIY51875.1 - 0.057 13.7 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) YlbE PF14003.6 KIY51875.1 - 0.07 13.6 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 YlbE-like protein AAA_17 PF13207.6 KIY51875.1 - 0.083 13.3 6.0 1.1 9.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KIY51875.1 - 0.1 12.5 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KIY51875.1 - 0.13 12.7 1.1 2.9 8.4 0.1 2.5 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KIY51875.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIY51875.1 - 0.18 12.1 0.3 0.41 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 KIY51875.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIY51875.1 - 0.48 11.0 0.0 0.48 11.0 0.0 2.8 3 1 0 3 3 2 0 AAA domain PIEZO PF15917.5 KIY51875.1 - 1.9 7.9 6.9 2.9 7.3 6.9 1.2 1 0 0 1 1 1 0 Piezo PI3K_1B_p101 PF10486.9 KIY51875.1 - 2.1 6.0 13.2 3.2 5.4 13.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF572 PF04502.13 KIY51875.1 - 2.3 7.8 17.1 4.5 6.8 17.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) TAF8_C PF10406.9 KIY51875.1 - 2.3 8.8 5.9 7 7.3 5.9 1.9 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term LMBR1 PF04791.16 KIY51875.1 - 4.2 6.2 7.8 6.4 5.6 7.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MPM1 PF17234.2 KIY51875.1 - 4.6 7.5 0.0 4.6 7.5 0.0 3.0 3 1 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 F-box-like PF12937.7 KIY51878.1 - 2.1e-05 24.3 0.8 7e-05 22.6 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY51878.1 - 0.011 15.5 0.5 1.1 9.2 0.0 2.9 2 0 0 2 2 2 0 F-box domain Na_H_Exchanger PF00999.21 KIY51879.1 - 8.5e-59 199.3 29.9 1.1e-58 198.9 29.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family dCMP_cyt_deam_1 PF00383.23 KIY51880.1 - 8.7e-18 64.1 0.2 1.1e-17 63.7 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KIY51880.1 - 1.1e-13 51.6 1.7 2.7e-12 47.0 0.4 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KIY51880.1 - 0.0011 18.7 1.3 0.16 11.6 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Ifi-6-16 PF06140.13 KIY51881.1 - 3.7e-07 30.0 0.8 6.7e-07 29.1 0.8 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Cofilin_ADF PF00241.20 KIY51882.1 - 3.9e-20 71.8 0.0 4.8e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MliC PF09864.9 KIY51882.1 - 0.047 13.6 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme RNase_H2_suC PF08615.11 KIY51883.1 - 4.4e-20 72.3 0.0 5.6e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) HAD_2 PF13419.6 KIY51884.1 - 3.5e-17 63.1 0.0 1.5e-10 41.4 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY51884.1 - 2.4e-13 50.9 0.0 2.4e-12 47.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY51884.1 - 3.4e-05 23.8 0.0 0.0001 22.3 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIY51884.1 - 0.044 14.2 0.0 0.23 11.8 0.0 2.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 KIY51885.1 - 4.4e-08 32.9 0.1 1.7e-07 31.0 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY51885.1 - 0.0014 18.5 0.0 0.014 15.3 0.0 2.7 2 1 0 2 2 2 1 F-box domain THOC7 PF05615.13 KIY51885.1 - 0.16 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 PRANC PF09372.10 KIY51885.1 - 0.17 12.2 0.0 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 PRANC domain Med10 PF09748.9 KIY51886.1 - 2.1e-17 63.2 0.1 2.7e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Ran_BP1 PF00638.18 KIY51887.1 - 2.7e-05 24.4 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain HNH_2 PF13391.6 KIY51888.1 - 0.0076 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DAGAT PF03982.13 KIY51889.1 - 8.7e-87 290.8 0.0 1.2e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase WEMBL PF05701.11 KIY51890.1 - 0.13 11.0 15.5 0.33 9.6 15.4 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.9 KIY51890.1 - 1.2 9.1 11.9 0.62 10.1 6.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SYS1 PF09801.9 KIY51891.1 - 1.8e-17 63.9 7.8 8.9e-11 42.1 4.4 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DnaJ PF00226.31 KIY51893.1 - 1.3e-11 44.4 0.0 1.7e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain SE PF08491.10 KIY51894.1 - 3.3e-31 108.3 0.0 4e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase Glyco_hydro_3_C PF01915.22 KIY51895.1 - 2.2e-48 165.0 0.0 5e-48 163.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY51895.1 - 4.1e-22 79.0 0.0 2e-21 76.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY51895.1 - 2.1e-18 66.2 0.0 4.3e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain EB PF01683.18 KIY51896.1 - 0.064 13.6 1.2 0.1 12.9 1.2 1.3 1 0 0 1 1 1 0 EB module TolA PF06519.11 KIY51896.1 - 0.14 12.4 0.3 15 5.8 0.2 2.2 1 1 1 2 2 2 0 TolA C-terminal DUF4048 PF13257.6 KIY51897.1 - 0.076 12.8 1.2 0.12 12.2 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) DPPIV_N PF00930.21 KIY51898.1 - 4.7e-80 269.0 0.0 7.1e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KIY51898.1 - 2e-44 151.6 1.0 3.4e-44 150.8 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KIY51898.1 - 1.4e-05 24.8 1.3 3.3e-05 23.6 1.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KIY51898.1 - 0.00048 19.8 0.2 0.00083 19.1 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KIY51898.1 - 0.075 12.6 0.2 0.39 10.2 0.2 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family PD40 PF07676.12 KIY51898.1 - 0.075 13.0 0.8 2 8.4 0.1 3.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ERCC3_RAD25_C PF16203.5 KIY51899.1 - 1.2e-120 401.3 0.0 2.3e-120 400.4 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KIY51899.1 - 8.6e-29 100.3 0.1 1.8e-28 99.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY51899.1 - 1.7e-17 63.9 0.0 4.9e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY51899.1 - 9.3e-13 48.5 0.1 3.3e-12 46.7 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIY51899.1 - 7.7e-10 38.0 0.2 1.1e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KIY51899.1 - 2.5e-06 27.4 0.1 5.4e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase WD40 PF00400.32 KIY51901.1 - 9.9e-36 121.2 28.0 1.8e-07 31.7 0.4 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY51901.1 - 2.5e-14 53.3 0.7 0.00096 19.4 0.0 6.1 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KIY51901.1 - 1.4e-11 44.0 0.3 3.6e-11 42.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KIY51901.1 - 5.3e-08 32.0 5.5 0.17 10.5 0.1 4.2 2 2 1 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY51901.1 - 2.1e-06 27.3 0.0 0.018 14.4 0.0 2.8 2 1 1 3 3 3 2 WD40-like domain F-box PF00646.33 KIY51901.1 - 0.00013 21.8 0.1 0.00028 20.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 KIY51901.1 - 0.00064 20.1 6.1 29 5.3 0.0 6.5 7 1 0 7 7 7 0 PQQ-like domain PQQ_2 PF13360.6 KIY51901.1 - 0.0012 18.5 0.7 1.6 8.3 0.3 3.2 1 1 1 3 3 3 2 PQQ-like domain PALB2_WD40 PF16756.5 KIY51901.1 - 0.0046 15.9 2.8 0.31 9.9 0.1 3.3 2 1 2 4 4 4 1 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 KIY51901.1 - 0.026 14.5 0.5 16 5.6 0.0 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat DUF5046 PF16465.5 KIY51901.1 - 0.054 12.9 0.2 58 3.0 0.0 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF5046) DUF3678 PF12435.8 KIY51901.1 - 7.7 6.0 6.6 6.1 6.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3678) TPR_2 PF07719.17 KIY51902.1 - 1e-28 97.0 3.3 0.00047 20.1 0.2 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIY51902.1 - 3.9e-28 96.1 0.4 0.00069 19.3 0.2 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KIY51902.1 - 8.5e-22 77.5 16.2 4.9e-08 33.5 1.0 5.0 4 1 1 5 5 5 4 Tetratricopeptide repeat DnaJ PF00226.31 KIY51902.1 - 1.6e-21 76.2 0.2 5.1e-21 74.6 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_9 PF13371.6 KIY51902.1 - 4.4e-16 58.8 18.5 4e-06 26.9 0.2 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY51902.1 - 1.8e-15 56.3 10.8 3.7e-05 23.3 0.4 6.2 5 1 1 6 6 6 3 TPR repeat TPR_12 PF13424.6 KIY51902.1 - 4.1e-12 46.2 12.1 0.00016 21.9 0.4 6.0 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY51902.1 - 1.1e-11 45.0 19.3 0.0082 16.6 0.2 5.9 3 3 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KIY51902.1 - 1.7e-10 40.8 24.1 0.0043 17.8 0.1 7.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY51902.1 - 2.9e-09 36.7 6.1 0.23 11.9 0.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY51902.1 - 7.5e-08 32.5 3.2 0.1 12.9 0.3 4.7 3 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KIY51902.1 - 1.5e-06 28.5 2.4 1.1 10.0 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY51902.1 - 3e-06 27.0 0.7 2.5 8.5 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY51902.1 - 4.4e-06 26.3 8.0 0.36 11.0 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY51902.1 - 4.6e-06 26.6 3.0 0.052 13.6 0.3 3.8 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KIY51902.1 - 0.0003 20.8 7.8 0.36 10.9 0.0 5.2 7 0 0 7 7 7 2 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 KIY51902.1 - 0.0014 17.7 0.4 0.15 11.0 0.0 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.14 KIY51902.1 - 0.042 13.3 3.9 2.9 7.2 0.0 3.8 3 2 2 5 5 5 0 Coatomer epsilon subunit SHNi-TPR PF10516.9 KIY51902.1 - 0.062 12.8 1.8 63 3.1 0.0 4.8 5 0 0 5 5 5 0 SHNi-TPR BTAD PF03704.17 KIY51902.1 - 0.14 12.6 14.0 2.9 8.3 2.0 4.4 1 1 0 3 3 3 0 Bacterial transcriptional activator domain TPM_phosphatase PF04536.14 KIY51902.1 - 0.14 12.3 2.1 13 6.0 0.1 2.9 3 0 0 3 3 2 0 TPM domain Alkyl_sulf_dimr PF14863.6 KIY51902.1 - 0.21 12.0 2.8 53 4.3 0.0 3.4 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 KIY51902.1 - 1.2 9.1 12.0 68 3.5 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY51902.1 - 4.3 8.2 14.6 26 5.8 0.0 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat Dynamin_M PF01031.20 KIY51903.1 - 2.7e-93 312.3 0.0 1e-91 307.1 0.0 2.6 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KIY51903.1 - 1.2e-54 184.9 0.0 2.1e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIY51903.1 - 2.9e-29 101.1 0.6 7.1e-29 99.8 0.6 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY51903.1 - 7.2e-05 22.8 0.0 0.00047 20.2 0.0 2.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIY51903.1 - 0.2 11.0 0.1 7 5.9 0.0 2.3 2 0 0 2 2 2 0 AIG1 family PWWP PF00855.17 KIY51904.1 - 8.1e-14 51.8 0.1 1.8e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 PWWP domain zf-HC5HC2H_2 PF13832.6 KIY51905.1 - 9.6e-34 115.9 10.9 1.4e-32 112.1 6.9 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KIY51905.1 - 1.3e-24 87.4 0.3 1.3e-24 87.4 0.3 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KIY51905.1 - 8e-24 83.7 2.7 8e-24 83.7 2.7 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KIY51905.1 - 2.5e-15 55.7 14.7 4.3e-15 55.0 3.0 3.6 3 0 0 3 3 3 2 PHD-finger PHD PF00628.29 KIY51905.1 - 5.9e-11 42.1 5.5 5.9e-11 42.1 5.5 3.0 4 0 0 4 4 3 2 PHD-finger Bromodomain PF00439.25 KIY51905.1 - 8.4e-10 38.6 0.3 2.2e-09 37.3 0.3 1.7 1 0 0 1 1 1 1 Bromodomain zf-PHD-like PF15446.6 KIY51905.1 - 0.0014 18.3 0.4 0.0014 18.3 0.4 2.6 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KIY51905.1 - 0.0022 17.8 0.4 0.0022 17.8 0.4 3.3 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 KIY51905.1 - 0.01 16.1 0.2 0.01 16.1 0.2 2.9 3 1 0 3 3 3 0 FYVE-type zinc finger C1_2 PF03107.16 KIY51905.1 - 0.034 14.4 0.8 0.034 14.4 0.8 3.0 3 0 0 3 3 2 0 C1 domain Prok-RING_1 PF14446.6 KIY51905.1 - 0.97 9.4 15.3 0.11 12.5 3.7 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RanBP PF00641.18 KIY51905.1 - 3.2 7.1 15.7 0.48 9.8 0.7 3.7 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others zf-RING-like PF08746.11 KIY51905.1 - 4 7.8 14.2 9.3 6.7 1.6 3.0 2 0 0 2 2 2 0 RING-like domain CAP_GLY PF01302.25 KIY51909.1 - 7.8e-26 89.9 1.3 1.2e-25 89.3 1.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KIY51909.1 - 9.7e-21 74.0 0.0 1.6e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain zf-RING_UBOX PF13445.6 KIY51910.1 - 0.0096 15.9 0.5 0.023 14.7 0.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY51910.1 - 0.039 13.8 0.2 0.11 12.4 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY51910.1 - 0.089 13.1 1.2 0.26 11.7 1.2 1.9 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KIY51910.1 - 0.18 12.1 3.4 0.35 11.2 2.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain SHS2_Rpb7-N PF03876.17 KIY51911.1 - 1.2e-12 48.1 0.0 1.9e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KIY51911.1 - 1.6e-11 44.4 0.5 3.2e-11 43.4 0.5 1.5 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KIY51911.1 - 0.00031 21.0 0.1 0.00047 20.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 RNA_pol_Rbc25 PF08292.12 KIY51912.1 - 8e-31 107.0 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KIY51912.1 - 4e-17 62.3 0.1 8.3e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GATA PF00320.27 KIY51913.1 - 6.7e-05 22.4 45.6 0.00075 19.0 6.9 4.5 4 0 0 4 4 4 3 GATA zinc finger DZR PF12773.7 KIY51913.1 - 2.5 8.2 27.3 1.3 9.1 1.6 4.6 2 1 0 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 KIY51913.1 - 9.9 5.5 20.0 1.4 8.4 2.3 3.3 3 1 0 3 3 3 0 NMD3 family Thioredoxin PF00085.20 KIY51914.1 - 9.2e-53 176.6 0.3 2.8e-28 97.9 0.2 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KIY51914.1 - 8e-14 52.0 0.0 3.5e-05 23.8 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KIY51914.1 - 5.3e-06 26.8 1.1 0.0098 16.3 0.5 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KIY51914.1 - 3.6e-05 23.3 0.7 0.26 10.6 0.0 3.0 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KIY51914.1 - 0.00027 21.2 0.3 0.63 10.4 0.0 3.8 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KIY51914.1 - 0.0011 19.0 0.5 0.0077 16.3 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.6 KIY51914.1 - 0.0063 16.7 0.6 0.33 11.1 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 KIY51914.1 - 0.019 15.1 0.3 1.3 9.3 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin-like TraF PF13728.6 KIY51914.1 - 0.035 13.9 2.6 0.048 13.5 0.0 2.4 2 1 1 3 3 3 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 KIY51914.1 - 0.051 13.5 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 AhpC/TSA family Yae1_N PF09811.9 KIY51915.1 - 0.00043 19.9 8.8 0.001 18.7 8.8 1.7 1 1 0 1 1 1 1 Essential protein Yae1, N terminal MIF4G PF02854.19 KIY51919.1 - 1.8e-22 80.0 0.4 2.6e-22 79.5 0.4 1.2 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KIY51919.1 - 3.2e-20 72.2 0.1 4.2e-19 68.6 0.0 2.8 3 0 0 3 3 3 1 MA3 domain zf-CCCH PF00642.24 KIY51920.1 - 5.3e-12 45.3 22.1 9.6e-06 25.4 1.5 5.3 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KIY51920.1 - 0.004 17.3 12.4 0.021 15.0 5.0 3.3 1 1 1 2 2 2 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 KIY51920.1 - 0.055 13.5 30.6 1.8 8.8 1.3 6.0 6 0 0 6 6 6 0 Zinc finger domain Colipase_C PF02740.14 KIY51920.1 - 0.45 10.7 2.3 12 6.2 0.2 2.6 2 0 0 2 2 2 0 Colipase, C-terminal domain zf-CCCH_4 PF18044.1 KIY51920.1 - 2.3 8.1 30.2 0.074 12.9 1.1 5.6 5 2 0 5 5 5 0 CCCH-type zinc finger Torus PF16131.5 KIY51920.1 - 5.9 7.6 20.0 2.8 8.7 0.5 4.5 1 1 3 4 4 4 0 Torus domain Defensin_beta PF00711.19 KIY51920.1 - 8.1 6.6 12.5 2.7 8.1 0.3 3.9 3 0 0 3 3 3 0 Beta defensin DUF1712 PF08217.11 KIY51921.1 - 2.6e-19 69.2 0.0 3.5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Methyltransf_11 PF08241.12 KIY51923.1 - 1.1e-17 64.4 0.1 2.3e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY51923.1 - 4.5e-17 62.6 0.2 9.8e-17 61.5 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY51923.1 - 1.7e-10 41.5 0.0 3.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY51923.1 - 3.2e-09 36.5 0.0 4.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIY51923.1 - 6.4e-09 35.8 0.0 9.5e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY51923.1 - 0.0015 18.4 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY51923.1 - 0.03 13.9 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 KIY51923.1 - 0.052 12.5 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 KIY51923.1 - 0.052 12.9 0.0 0.075 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RNA_polI_A34 PF08208.11 KIY51924.1 - 0.18 11.9 1.3 0.52 10.4 0.2 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Dak1 PF02733.17 KIY51925.1 - 7.7e-93 310.8 0.1 1.1e-92 310.3 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KIY51925.1 - 4.6e-41 140.6 2.1 7.9e-41 139.8 2.1 1.4 1 0 0 1 1 1 1 DAK2 domain Cyto_heme_lyase PF01265.17 KIY51926.1 - 9.6e-83 278.1 8.0 1.1e-81 274.7 8.0 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase APH PF01636.23 KIY51927.1 - 1e-18 68.1 0.1 1.5e-18 67.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIY51927.1 - 0.0079 15.1 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KIY51927.1 - 0.033 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 KIY51927.1 - 0.073 12.4 0.0 4.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.20 KIY51927.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Spermine_synth PF01564.17 KIY51928.1 - 0.00015 21.2 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain SieB PF14163.6 KIY51928.1 - 0.089 12.3 1.3 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B GMC_oxred_N PF00732.19 KIY51929.1 - 1.2e-45 156.1 0.0 1.7e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY51929.1 - 4.2e-32 111.7 0.0 8.1e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Tim44 PF04280.15 KIY51930.1 - 1.5e-34 119.2 1.3 1.5e-34 119.2 1.3 1.7 2 0 0 2 2 2 1 Tim44-like domain STAT2_C PF12188.8 KIY51930.1 - 0.02 14.8 0.1 0.11 12.5 0.1 2.2 1 1 1 2 2 2 0 Signal transducer and activator of transcription 2 C terminal DMPK_coil PF08826.10 KIY51930.1 - 0.12 12.5 2.7 0.17 12.0 0.8 2.3 1 1 1 2 2 2 0 DMPK coiled coil domain like Ribosomal_S20p PF01649.18 KIY51930.1 - 0.27 11.9 4.4 0.15 12.7 0.6 2.4 2 0 0 2 2 2 0 Ribosomal protein S20 DUF3813 PF12758.7 KIY51930.1 - 4.1 7.8 8.6 13 6.2 3.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) zf-MYND PF01753.18 KIY51931.1 - 8.7e-09 35.3 15.4 1.2e-08 34.9 15.4 1.2 1 0 0 1 1 1 1 MYND finger ubiquitin PF00240.23 KIY51932.1 - 3.7e-15 55.4 0.0 5.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KIY51932.1 - 5.3e-11 42.2 0.1 1.4e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KIY51932.1 - 5.8e-06 26.0 0.0 9.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KIY51932.1 - 0.0037 17.2 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KIY51932.1 - 0.0073 16.9 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain STI1 PF17830.1 KIY51932.1 - 0.0083 16.0 13.1 0.3 11.1 4.2 3.0 2 1 0 2 2 2 2 STI1 domain RPN13_C PF16550.5 KIY51932.1 - 0.027 14.6 1.6 0.084 13.1 1.6 1.8 1 1 0 1 1 1 0 UCH-binding domain Ubiquitin_4 PF18036.1 KIY51932.1 - 0.078 13.0 0.2 0.46 10.6 0.2 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain HOIP-UBA PF16678.5 KIY51932.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 KIY51932.1 - 0.11 12.5 4.8 1.4 8.9 4.7 2.2 1 1 0 1 1 1 0 Spore germination GerD central core domain Ubiquitin_2 PF14560.6 KIY51932.1 - 0.14 12.6 0.1 0.59 10.6 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 KIY51932.1 - 0.36 10.6 2.3 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 CUE domain HATPase_c PF02518.26 KIY51934.1 - 7.3e-17 61.9 0.2 1.5e-16 60.8 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIY51934.1 - 4.1e-08 33.4 0.0 0.00012 22.2 0.0 2.8 3 0 0 3 3 3 2 Response regulator receiver domain Lipoprotein_2 PF00921.17 KIY51934.1 - 0.076 12.6 7.2 0.11 12.0 7.2 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein IBV_3C PF03620.13 KIY51934.1 - 9.5 6.8 6.0 5.2 7.6 1.8 2.5 2 0 0 2 2 2 0 IBV 3C protein GCFC PF07842.12 KIY51936.1 - 4.7e-74 249.5 11.2 6.7e-74 249.0 11.2 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KIY51936.1 - 5.3e-12 45.4 1.1 1.4e-11 44.1 1.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KIY51936.1 - 2.4e-06 27.5 0.8 2.4e-06 27.5 0.8 2.2 2 0 0 2 2 2 1 G-patch domain AAA PF00004.29 KIY51937.1 - 2.1e-42 144.7 0.0 4.3e-42 143.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY51937.1 - 2.5e-13 49.6 0.7 4.9e-13 48.7 0.2 1.8 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KIY51937.1 - 4.2e-11 42.6 0.5 1e-10 41.4 0.0 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KIY51937.1 - 1.9e-07 31.6 0.1 0.00014 22.3 0.1 2.9 2 1 2 4 4 3 1 AAA ATPase domain AAA_5 PF07728.14 KIY51937.1 - 4.7e-07 29.9 0.1 5.7e-06 26.4 0.1 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIY51937.1 - 9.7e-06 25.4 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KIY51937.1 - 1.2e-05 25.6 0.0 3.2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIY51937.1 - 0.00011 22.5 0.1 0.0054 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KIY51937.1 - 0.00088 19.8 0.2 0.0064 17.0 0.0 2.4 3 0 0 3 3 2 1 AAA domain Prot_ATP_OB_N PF17758.1 KIY51937.1 - 0.0016 18.0 0.1 0.0069 16.0 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 KIY51937.1 - 0.0018 17.5 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KIY51937.1 - 0.0029 17.0 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KIY51937.1 - 0.003 17.1 0.0 0.0066 16.0 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KIY51937.1 - 0.0045 17.3 0.0 0.009 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KIY51937.1 - 0.0053 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KIY51937.1 - 0.0053 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIY51937.1 - 0.0064 16.7 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY51937.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 KIY51937.1 - 0.0094 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY51937.1 - 0.013 15.2 0.1 0.035 13.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 KIY51937.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KIY51937.1 - 0.015 15.3 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KIY51937.1 - 0.016 14.9 0.0 0.059 13.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 KIY51937.1 - 0.02 14.2 1.7 0.16 11.3 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 KIY51937.1 - 0.024 14.9 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIY51937.1 - 0.025 14.1 0.1 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KIY51937.1 - 0.062 13.2 0.0 0.17 11.8 0.0 1.7 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KIY51937.1 - 0.063 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KIY51937.1 - 0.069 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KIY51937.1 - 0.073 12.7 0.2 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Mnd1 PF03962.15 KIY51937.1 - 0.08 13.2 0.3 0.2 12.0 0.3 1.6 1 0 0 1 1 1 0 Mnd1 HTH domain AAA_19 PF13245.6 KIY51937.1 - 0.11 12.8 0.1 0.35 11.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 KIY51937.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 KIY51937.1 - 0.12 12.8 2.6 17 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KIY51937.1 - 0.13 12.0 2.5 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Peptidase_S10 PF00450.22 KIY51939.1 - 2.5e-68 231.4 2.2 7.6e-43 147.5 2.7 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Glyco_hydro_cc PF11790.8 KIY51940.1 - 1.2e-54 185.4 3.1 1.5e-54 185.2 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.13 KIY51940.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 DUF447 PF04289.12 KIY51940.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Sortilin-Vps10 PF15902.5 KIY51941.1 - 2.4e-292 969.3 8.9 1.4e-153 511.9 2.9 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KIY51941.1 - 1.6e-91 305.2 13.6 1.1e-47 162.5 3.2 2.6 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KIY51941.1 - 2.4e-10 38.8 44.5 1.2 9.4 2.0 12.1 11 0 0 11 11 11 7 BNR/Asp-box repeat CHB_HEX_C PF03174.13 KIY51941.1 - 1.6e-06 28.0 5.4 0.47 10.5 0.0 5.8 6 0 0 6 6 6 2 Chitobiase/beta-hexosaminidase C-terminal domain BNR_2 PF13088.6 KIY51941.1 - 3e-05 23.5 5.2 1.9 7.7 0.0 5.7 5 1 0 5 5 5 2 BNR repeat-like domain PSII_BNR PF14870.6 KIY51941.1 - 0.00068 19.0 0.3 2.2 7.5 0.0 3.9 4 0 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 Fe_dep_repr_C PF02742.15 KIY51941.1 - 0.018 15.1 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain DUF1939 PF09154.10 KIY51941.1 - 0.093 12.9 0.0 0.4 10.9 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) BNR_6 PF15899.5 KIY51941.1 - 0.99 9.7 4.0 6.6 7.1 0.5 3.8 3 0 0 3 3 3 0 BNR-Asp box repeat DnaJ_CXXCXGXG PF00684.19 KIY51942.1 - 6.7e-05 23.2 7.7 0.018 15.4 0.7 2.4 2 0 0 2 2 2 2 DnaJ central domain DUF5351 PF17302.2 KIY51942.1 - 0.043 14.0 1.2 0.043 14.0 1.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5351) DUF2318 PF10080.9 KIY51942.1 - 0.15 12.2 0.3 0.28 11.3 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Anti-TRAP PF15777.5 KIY51942.1 - 0.47 10.5 11.2 0.11 12.5 1.0 3.0 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein WD40 PF00400.32 KIY51943.1 - 0.0004 21.1 7.4 0.0084 16.9 0.4 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Phage_integrase PF00589.22 KIY51944.1 - 0.012 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family Pkinase PF00069.25 KIY51945.1 - 1.4e-31 109.8 0.0 4.6e-30 104.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51945.1 - 1e-09 38.1 0.5 1.1e-06 28.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase DAHP_synth_2 PF01474.16 KIY51947.1 - 1.2e-139 465.6 0.0 1.7e-80 270.7 0.0 3.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family Malic_M PF03949.15 KIY51948.1 - 2.1e-82 276.2 0.0 3e-82 275.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIY51948.1 - 6.8e-59 198.7 0.0 1e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SnoaL_2 PF12680.7 KIY51949.1 - 0.072 13.7 0.1 0.093 13.4 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like domain F-box-like PF12937.7 KIY51950.1 - 6e-05 22.8 0.5 0.00026 20.8 0.5 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY51950.1 - 0.0013 18.6 2.2 0.0013 18.6 2.2 2.3 2 0 0 2 2 2 1 F-box domain TFIID_20kDa PF03847.13 KIY51951.1 - 6.7e-25 87.4 1.4 7.2e-25 87.3 1.4 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 KIY51951.1 - 0.01 15.9 0.0 0.01 15.9 0.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KIY51951.1 - 0.14 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Indigoidine_A PF04227.12 KIY51953.1 - 7.7e-124 412.8 1.0 3.5e-122 407.3 0.0 2.6 3 0 0 3 3 3 2 Indigoidine synthase A like protein PfkB PF00294.24 KIY51953.1 - 4.7e-23 81.9 0.4 1.3e-11 44.4 0.4 2.9 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Pkinase PF00069.25 KIY51954.1 - 2.8e-09 36.7 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51954.1 - 0.0074 15.6 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Redoxin PF08534.10 KIY51956.1 - 0.00064 19.5 0.0 0.034 13.8 0.0 2.1 2 0 0 2 2 2 2 Redoxin CDP-OH_P_transf PF01066.21 KIY51957.1 - 1.5e-16 60.9 0.1 1.5e-16 60.9 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PAP_assoc PF03828.19 KIY51957.1 - 0.00011 22.3 0.0 0.00032 20.9 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Pkinase PF00069.25 KIY51958.1 - 4.3e-10 39.4 0.0 6.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY51958.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Malic_M PF03949.15 KIY51959.1 - 0.0074 15.6 0.0 0.057 12.7 0.0 1.9 1 1 1 2 2 2 2 Malic enzyme, NAD binding domain RdRP PF05183.12 KIY51960.1 - 3.3e-94 316.6 0.0 4.6e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Big_6 PF17936.1 KIY51961.1 - 0.11 12.8 1.0 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 Bacterial Ig domain MARVEL PF01284.23 KIY51963.1 - 1.3e-11 44.7 19.8 1.5e-11 44.5 19.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain Tenui_NCP PF04876.12 KIY51963.1 - 0.032 13.8 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein DUF2070 PF09843.9 KIY51963.1 - 6.1 5.0 9.5 8 4.6 9.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RhoGEF PF00621.20 KIY51964.1 - 2.9e-13 50.5 0.0 7.3e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 KIY51964.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Ribosomal_L28e PF01778.17 KIY51966.1 - 1.1e-27 97.1 0.0 1.2e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family Baculo_PEP_C PF04513.12 KIY51967.1 - 0.076 13.1 10.9 0.064 13.3 5.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PAP_assoc PF03828.19 KIY51968.1 - 1.3e-12 47.7 0.0 2.5e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIY51968.1 - 1.1e-06 28.8 0.0 5.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 KIY51968.1 - 0.016 15.4 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase beta palm Polbeta PF18765.1 KIY51968.1 - 0.038 14.1 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase MFS_1 PF07690.16 KIY51969.1 - 2.5e-37 128.6 25.5 2.5e-37 128.6 25.5 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HCMV_UL124 PF17609.2 KIY51969.1 - 0.078 13.2 1.5 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function TMIE PF16038.5 KIY51969.1 - 3.7 7.5 4.8 0.92 9.4 0.1 2.3 2 0 0 2 2 2 0 TMIE protein CDP-OH_P_transf PF01066.21 KIY51970.1 - 6.8e-17 62.0 0.1 6.8e-17 62.0 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Redoxin PF08534.10 KIY51971.1 - 3.6e-27 94.9 0.0 4.4e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIY51971.1 - 7.9e-12 45.2 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family zf-C2H2 PF00096.26 KIY51972.1 - 6.2e-10 39.0 10.8 2.5e-05 24.5 1.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY51972.1 - 1.1e-05 25.6 5.1 1.1e-05 25.6 5.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY51972.1 - 5.2e-05 23.7 10.1 0.026 15.4 1.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIY51972.1 - 0.003 18.2 3.4 1.3 9.7 0.3 2.2 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KIY51972.1 - 0.0057 16.9 1.1 0.0073 16.6 1.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon FANCL_C PF11793.8 KIY51972.1 - 0.012 15.8 0.5 0.016 15.3 0.5 1.2 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C2H2_jaz PF12171.8 KIY51972.1 - 0.03 14.6 7.3 0.16 12.3 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_12 PF18658.1 KIY51972.1 - 0.092 12.3 2.1 0.17 11.5 2.1 1.5 1 1 0 1 1 1 0 Zinc-finger C2H2-type zf-met PF12874.7 KIY51972.1 - 0.11 12.9 0.4 0.11 12.9 0.4 2.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KIY51972.1 - 0.26 11.4 5.5 1.7 8.8 0.8 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-BED PF02892.15 KIY51972.1 - 0.35 10.9 4.9 1.1 9.4 0.7 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 KIY51973.1 - 2.2e-11 43.5 14.8 2.2e-05 24.6 5.0 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY51973.1 - 2.2e-06 28.0 13.7 0.0029 18.3 4.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY51973.1 - 4.9e-05 23.6 15.7 0.00011 22.5 5.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 KIY51973.1 - 0.0002 21.9 5.6 0.072 13.7 0.5 2.2 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KIY51973.1 - 0.77 9.9 7.7 4.1 7.5 2.1 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 KIY51973.1 - 6.1 6.7 10.0 1.8 8.4 1.7 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type EF-hand_1 PF00036.32 KIY51974.1 - 2.1e-27 92.6 17.1 2.4e-09 36.1 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIY51974.1 - 3.7e-26 91.4 14.5 3.7e-13 49.7 5.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY51974.1 - 8.4e-23 78.3 12.1 2e-08 33.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KIY51974.1 - 1.4e-14 53.7 15.8 6.6e-09 35.5 1.8 3.6 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KIY51974.1 - 1.3e-11 44.6 2.3 2.6e-05 24.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KIY51974.1 - 1.8e-11 43.0 7.2 0.0011 18.4 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 KIY51974.1 - 1.8e-08 34.3 8.0 0.00046 20.1 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KIY51974.1 - 0.00011 22.2 3.0 0.043 13.8 0.0 3.5 2 1 2 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 KIY51974.1 - 0.0052 17.1 3.8 0.37 11.1 0.3 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 KIY51974.1 - 0.0099 16.2 2.6 0.23 11.8 0.4 2.5 2 1 0 2 2 2 1 EF-hand domain DUF1636 PF07845.11 KIY51974.1 - 0.019 15.4 0.0 2.5 8.6 0.0 2.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1636) DUF1059 PF06348.11 KIY51974.1 - 0.061 13.6 0.3 0.87 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) SurA_N_2 PF13623.6 KIY51974.1 - 0.092 12.6 1.3 3.5 7.5 0.3 2.4 2 1 0 2 2 2 0 SurA N-terminal domain HTH_40 PF14493.6 KIY51974.1 - 0.15 12.5 0.3 15 6.2 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Polysacc_deac_1 PF01522.21 KIY51975.1 - 0.00059 19.7 0.6 0.0022 17.9 0.6 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase p450 PF00067.22 KIY51977.1 - 6.6e-44 150.4 0.0 9.8e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4663 PF15668.5 KIY51978.1 - 0.014 14.5 12.0 0.0046 16.1 7.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4663) F-box-like PF12937.7 KIY51979.1 - 0.00087 19.1 1.0 0.23 11.4 0.1 2.7 2 0 0 2 2 2 2 F-box-like AflR PF08493.10 KIY51979.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein adh_short_C2 PF13561.6 KIY51980.1 - 3.9e-21 75.7 0.2 8.5e-21 74.6 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51980.1 - 5.6e-12 45.5 0.3 8.5e-12 44.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51980.1 - 0.00059 19.8 0.3 0.00091 19.2 0.3 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIY51980.1 - 0.0017 18.6 0.1 0.0026 18.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KIY51980.1 - 0.012 16.1 0.1 0.023 15.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.8 KIY51980.1 - 0.016 15.0 1.1 0.034 13.9 1.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RhoGEF PF00621.20 KIY51982.1 - 1.8e-09 38.1 0.2 7.9e-08 32.7 0.1 2.2 2 0 0 2 2 2 2 RhoGEF domain NIF PF03031.18 KIY51983.1 - 4.3e-39 133.8 0.0 6e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase adh_short_C2 PF13561.6 KIY51986.1 - 1.5e-20 73.8 0.1 1.4e-11 44.4 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY51986.1 - 1.3e-14 54.1 0.0 2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY51986.1 - 0.00048 20.1 0.3 0.00071 19.5 0.3 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KIY51986.1 - 0.0073 16.9 0.2 0.013 16.0 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KIY51986.1 - 0.012 15.8 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 KIY51986.1 - 0.019 14.7 1.0 0.038 13.8 1.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_M24 PF00557.24 KIY51987.1 - 8.2e-41 140.0 0.1 1.1e-40 139.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDT1_C PF16679.5 KIY51987.1 - 0.18 12.3 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Abhydrolase_3 PF07859.13 KIY51988.1 - 1.9e-49 168.4 0.1 2.6e-49 168.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY51988.1 - 7.3e-15 54.7 0.0 3.8e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KIY51988.1 - 0.00055 18.9 0.0 0.12 11.2 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 KIY51988.1 - 0.00085 18.9 0.0 0.0049 16.4 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KIY51988.1 - 0.0009 19.9 2.6 0.0009 19.9 2.6 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY51988.1 - 0.0088 15.7 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY51988.1 - 0.028 13.7 0.2 0.19 11.0 0.1 2.2 2 1 0 2 2 2 0 Serine aminopeptidase, S33 HA2 PF04408.23 KIY51989.1 - 1.1e-17 64.3 2.1 1.2e-17 64.1 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY51989.1 - 5.6e-15 55.5 0.0 1.1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY51989.1 - 6.6e-12 45.8 0.1 1.7e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY51989.1 - 6.4e-10 39.1 0.3 5e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY51989.1 - 0.0097 16.2 0.1 0.037 14.3 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY51989.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvA_C PF07499.13 KIY51989.1 - 0.15 12.6 0.0 0.8 10.2 0.0 2.3 1 0 0 1 1 1 0 RuvA, C-terminal domain NACHT PF05729.12 KIY51989.1 - 0.18 11.7 0.1 0.41 10.5 0.1 1.7 1 1 0 1 1 1 0 NACHT domain Sugar_tr PF00083.24 KIY51992.1 - 1.5e-109 366.9 20.1 2e-109 366.4 20.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY51992.1 - 2.2e-24 86.0 73.9 7.4e-20 71.2 37.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SH3_1 PF00018.28 KIY51993.1 - 0.00035 20.1 0.1 0.0006 19.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIY51993.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4131 PF13567.6 KIY51993.1 - 0.0085 15.8 0.3 0.017 14.8 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) SH3_3 PF08239.11 KIY51993.1 - 0.092 13.0 0.2 0.19 12.1 0.2 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_9 PF14604.6 KIY51993.1 - 0.18 11.7 0.2 0.37 10.7 0.2 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF3488 PF11992.8 KIY51994.1 - 0.17 10.8 8.2 0.049 12.6 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) DUF4131 PF13567.6 KIY51994.1 - 0.43 10.2 9.2 0.56 9.9 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1614 PF07758.11 KIY51994.1 - 1.2 9.2 7.9 0.28 11.2 4.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1614) S4 PF01479.25 KIY51995.1 - 1.1e-11 44.2 0.9 1.1e-11 44.2 0.9 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KIY51995.1 - 1.2e-06 29.4 0.1 2.2e-06 28.5 0.1 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 KIY51996.1 - 1.2e-43 147.1 4.2 1.7e-43 146.6 4.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e VASt PF16016.5 KIY51998.1 - 9.4e-35 120.3 0.2 1.4e-34 119.7 0.2 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KIY51998.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 GRAM domain RRM_1 PF00076.22 KIY52004.1 - 5.4e-28 96.6 0.3 4.4e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY52004.1 - 5.5e-12 45.4 0.0 1.6e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY52004.1 - 1.1e-10 41.2 0.1 1.1e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Exo_endo_phos PF03372.23 KIY52005.1 - 2.1e-21 76.5 0.1 2.7e-21 76.2 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTF2 PF02136.20 KIY52006.1 - 2.1e-11 44.5 0.0 1.8e-10 41.4 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KIY52006.1 - 3.8e-07 30.2 0.0 4.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SnoaL_2 PF12680.7 KIY52006.1 - 0.0095 16.6 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Wbp11 PF09429.10 KIY52008.1 - 7.4e-22 77.6 13.6 1.3e-21 76.8 13.6 1.4 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 KIY52008.1 - 4.6e-13 49.7 17.4 4.6e-13 49.7 17.4 6.7 4 2 0 4 4 4 1 mRNA biogenesis factor DUF2247 PF10004.9 KIY52008.1 - 0.14 11.9 0.5 0.21 11.4 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) APG6_N PF17675.1 KIY52008.1 - 0.77 10.3 11.5 1.3 9.6 11.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region GNVR PF13807.6 KIY52010.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Exo5 PF09810.9 KIY52012.1 - 1.2e-58 199.4 0.0 1.4e-57 195.9 0.0 2.1 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KIY52012.1 - 0.019 14.9 1.6 3.8 7.4 0.0 3.4 3 1 0 3 3 3 0 PD-(D/E)XK nuclease superfamily UIM PF02809.20 KIY52012.1 - 0.077 12.9 3.2 0.4 10.7 3.2 2.4 1 0 0 1 1 1 0 Ubiquitin interaction motif Sugar_tr PF00083.24 KIY52013.1 - 2.9e-105 352.7 12.3 3.5e-105 352.5 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY52013.1 - 4.9e-12 45.4 33.8 2.8e-07 29.8 8.7 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF2232 PF09991.9 KIY52013.1 - 0.0048 16.1 1.2 0.0048 16.1 1.2 2.3 3 0 0 3 3 3 1 Predicted membrane protein (DUF2232) DUF2062 PF09835.9 KIY52014.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) RTX PF02382.15 KIY52015.1 - 0.74 9.4 10.8 0.061 13.0 6.2 1.5 2 0 0 2 2 2 0 N-terminal domain in RTX protein ATP1G1_PLM_MAT8 PF02038.16 KIY52015.1 - 6.3 6.3 5.6 23 4.5 2.3 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family NAD_binding_2 PF03446.15 KIY52016.1 - 1.4e-21 77.4 0.1 1.9e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KIY52016.1 - 5.1e-10 39.6 0.0 1.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KIY52016.1 - 3.7e-07 30.3 0.0 7.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIY52016.1 - 2.7e-06 27.9 0.0 7.8e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KIY52016.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 KIY52016.1 - 0.0026 16.7 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_Gly3P_dh_N PF01210.23 KIY52016.1 - 0.062 13.3 0.2 0.42 10.6 0.2 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.6 KIY52016.1 - 0.1 12.5 0.2 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding ApbA PF02558.16 KIY52016.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.6 KIY52017.1 - 3.8e-12 46.3 0.5 4.8e-12 45.9 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY52017.1 - 6.2e-10 38.8 0.6 1.9e-09 37.3 0.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY52017.1 - 0.00029 20.8 0.2 0.00038 20.4 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KIY52017.1 - 0.011 16.3 0.2 0.02 15.4 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KIY52017.1 - 0.016 15.4 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1015 PF06245.11 KIY52017.1 - 0.057 12.3 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) MIOX PF05153.15 KIY52019.1 - 2e-118 394.5 0.1 2.4e-118 394.2 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KIY52019.1 - 0.002 18.3 0.1 0.11 12.8 0.1 2.3 1 1 0 1 1 1 1 HD domain Sugar_tr PF00083.24 KIY52020.1 - 7.9e-75 252.4 8.6 8.9e-75 252.3 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY52020.1 - 8.3e-05 21.7 25.6 0.0018 17.3 9.9 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily AgrB PF04647.15 KIY52020.1 - 0.61 9.4 3.7 3.2 7.0 0.1 2.6 1 1 1 2 2 2 0 Accessory gene regulator B DUF3611 PF12263.8 KIY52020.1 - 6.4 6.6 10.4 2.2 8.1 4.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) FMN_dh PF01070.18 KIY52021.1 - 3.4e-110 368.4 0.0 4.3e-110 368.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KIY52021.1 - 2.1e-05 23.9 0.1 3.1e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIY52021.1 - 3.3e-05 23.1 0.5 0.0011 18.1 0.1 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KIY52021.1 - 0.00018 20.9 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_syn_central PF04898.14 KIY52021.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain APH PF01636.23 KIY52024.1 - 4.4e-07 30.1 0.4 6.3e-07 29.6 0.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY52024.1 - 0.00024 20.7 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KIY52024.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase F-box-like PF12937.7 KIY52025.1 - 5.2e-05 23.0 0.2 0.00018 21.3 0.2 2.0 1 1 0 1 1 1 1 F-box-like GIT_SHD PF08518.11 KIY52026.1 - 6.2e-27 92.9 4.8 1.4e-13 50.2 0.5 2.8 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT Bax1-I PF01027.20 KIY52027.1 - 1.2e-40 139.6 12.3 1.3e-40 139.5 12.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Sec1 PF00995.23 KIY52028.1 - 8.1e-118 395.1 0.0 1e-117 394.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Retrotran_gag_2 PF14223.6 KIY52031.1 - 1.3e-10 41.1 0.1 2.2e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KIY52032.1 - 6e-11 42.2 0.2 8.9e-08 31.9 0.0 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIY52032.1 - 0.037 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) RVT_1 PF00078.27 KIY52033.1 - 1.6e-06 27.8 0.0 4.1e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 KIY52035.1 - 3.2e-17 62.5 29.6 1.3e-16 60.5 29.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.16 KIY52035.1 - 0.015 15.3 2.1 0.015 15.3 2.1 3.1 3 0 0 3 3 3 0 Ion channel LapA_dom PF06305.11 KIY52035.1 - 0.096 12.5 1.6 6.4 6.7 0.0 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF423 PF04241.15 KIY52036.1 - 0.41 10.9 3.9 0.41 10.9 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Mad3_BUB1_I PF08311.12 KIY52037.1 - 3.8e-27 94.7 0.3 6.2e-27 94.0 0.3 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KIY52037.1 - 1.7e-13 50.6 0.0 2.1e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52037.1 - 4.5e-05 22.9 0.0 7.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 KIY52037.1 - 0.0013 18.9 0.0 0.0048 17.0 0.0 1.9 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Kdo PF06293.14 KIY52037.1 - 0.099 12.0 0.0 0.25 10.6 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAD_SRA PF02182.17 KIY52038.1 - 7.1e-21 74.5 0.4 8e-21 74.4 0.4 1.0 1 0 0 1 1 1 1 SAD/SRA domain PigN PF04987.14 KIY52039.1 - 1.1e-115 387.1 32.4 1.5e-115 386.7 32.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KIY52039.1 - 2.1e-07 30.8 0.6 0.002 17.8 0.8 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KIY52039.1 - 0.00057 19.4 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Mucin-like PF16058.5 KIY52040.1 - 0.041 14.0 4.7 0.05 13.7 4.7 1.1 1 0 0 1 1 1 0 Mucin-like DUF5428 PF17493.2 KIY52040.1 - 0.081 13.4 0.4 0.12 12.8 0.4 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5428) MFS_1 PF07690.16 KIY52041.1 - 9.4e-15 54.4 28.5 9.4e-15 54.4 28.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TetR_C_16 PF17920.1 KIY52041.1 - 0.88 9.8 6.6 0.83 9.9 1.4 2.7 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Cellulase PF00150.18 KIY52042.1 - 9.9e-07 28.5 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BRI3BP PF14965.6 KIY52042.1 - 0.00052 19.6 0.1 0.008 15.7 0.0 2.2 2 0 0 2 2 2 1 Negative regulator of p53/TP53 2OG-FeII_Oxy_3 PF13640.6 KIY52044.1 - 1.1e-07 32.6 0.0 3.8e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4041 PF13250.6 KIY52045.1 - 0.18 11.7 0.0 6.5 6.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) F-box-like PF12937.7 KIY52046.1 - 4.2e-09 36.2 0.2 1.2e-08 34.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY52046.1 - 0.017 15.0 1.3 0.11 12.3 1.3 2.4 1 1 0 1 1 1 0 F-box domain Proteasome PF00227.26 KIY52047.1 - 3.8e-46 157.0 0.1 4.7e-46 156.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KIY52047.1 - 1.1e-11 43.9 0.1 1.1e-11 43.9 0.1 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NAD_Gly3P_dh_C PF07479.14 KIY52047.1 - 0.036 14.3 0.2 0.08 13.2 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SnoaL_2 PF12680.7 KIY52048.1 - 0.002 18.7 0.0 0.0028 18.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIY52048.1 - 0.0026 18.2 0.0 0.0032 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) FCH PF00611.23 KIY52049.1 - 2.1e-14 53.5 0.0 7.8e-14 51.7 0.0 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KIY52049.1 - 8.1e-11 41.4 0.1 1.7e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY52049.1 - 5.5e-09 35.7 0.1 1e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY52049.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF1690 PF07956.11 KIY52049.1 - 0.0084 16.5 6.2 0.013 15.9 5.7 1.6 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) F-box-like PF12937.7 KIY52050.1 - 7.5e-05 22.6 1.5 0.00023 21.0 1.5 1.8 1 0 0 1 1 1 1 F-box-like Sdh_cyt PF01127.22 KIY52051.1 - 3.9e-22 78.6 1.5 5e-22 78.2 1.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit UPF0220 PF05255.11 KIY52051.1 - 0.073 12.6 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Ribosomal_L30 PF00327.20 KIY52052.1 - 5.6e-10 39.0 0.1 8.6e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF5407 PF17401.2 KIY52052.1 - 0.05 13.9 0.1 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5407) AAA PF00004.29 KIY52053.1 - 3.5e-93 309.0 0.0 3e-47 160.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY52053.1 - 4.2e-18 64.9 0.8 4.2e-08 32.9 0.2 2.9 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KIY52053.1 - 1.4e-15 57.4 0.0 7.4e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIY52053.1 - 8.8e-13 48.7 0.2 0.013 15.8 0.0 5.3 2 2 2 4 4 4 2 AAA domain AAA_16 PF13191.6 KIY52053.1 - 3.6e-12 47.0 2.6 0.00048 20.6 0.0 4.6 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 KIY52053.1 - 1.7e-10 41.1 0.5 0.00082 19.4 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KIY52053.1 - 2.9e-10 40.5 0.0 0.00014 22.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KIY52053.1 - 3.5e-10 40.3 0.0 0.00056 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KIY52053.1 - 1.6e-09 37.4 0.0 4.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 KIY52053.1 - 6.6e-08 32.9 0.0 0.023 15.1 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 KIY52053.1 - 7.2e-08 32.5 0.0 0.0085 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KIY52053.1 - 3.9e-07 29.6 0.6 0.023 14.1 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KIY52053.1 - 7.7e-07 29.0 0.0 0.055 13.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KIY52053.1 - 1.2e-06 28.9 0.0 0.026 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KIY52053.1 - 2.9e-06 27.2 0.0 0.0089 15.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIY52053.1 - 5.1e-06 26.5 0.5 0.1 12.5 0.0 3.5 3 1 1 4 4 3 2 NACHT domain ABC_tran PF00005.27 KIY52053.1 - 7.6e-06 26.5 0.0 0.11 13.1 0.0 2.6 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 KIY52053.1 - 8.1e-06 25.9 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 KIY52053.1 - 1.4e-05 25.3 0.0 0.0051 17.0 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_18 PF13238.6 KIY52053.1 - 1.7e-05 25.4 0.0 0.31 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KIY52053.1 - 3.2e-05 23.4 0.1 0.7 9.2 0.0 3.2 2 1 0 3 3 3 2 KaiC AAA_25 PF13481.6 KIY52053.1 - 3.9e-05 23.3 2.1 2.8 7.5 0.1 4.3 3 1 1 4 4 4 2 AAA domain AAA_17 PF13207.6 KIY52053.1 - 4e-05 24.0 0.0 0.096 13.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KIY52053.1 - 5.2e-05 23.2 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 KIY52053.1 - 8.5e-05 21.9 0.0 0.41 9.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Sigma54_activat PF00158.26 KIY52053.1 - 0.00012 21.8 0.0 0.63 9.7 0.0 3.3 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 KIY52053.1 - 0.00024 20.7 0.0 0.78 9.2 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 KIY52053.1 - 0.00027 20.2 0.0 0.011 14.9 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 KIY52053.1 - 0.00043 19.6 0.0 0.94 8.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.18 KIY52053.1 - 0.00056 19.7 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 KIY52053.1 - 0.00056 20.0 0.0 1.2 9.3 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain Vps4_C PF09336.10 KIY52053.1 - 0.001 19.0 0.0 2.9 7.9 0.0 2.8 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 KIY52053.1 - 0.0013 17.9 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KIY52053.1 - 0.0025 17.6 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIY52053.1 - 0.0028 17.6 0.0 2.2 8.1 0.0 2.9 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea SKI PF01202.22 KIY52053.1 - 0.0032 17.6 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase PhoH PF02562.16 KIY52053.1 - 0.0037 16.8 0.1 2.8 7.4 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 KIY52053.1 - 0.0039 16.9 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIY52053.1 - 0.02 14.2 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KIY52053.1 - 0.021 14.7 0.0 6.4 6.6 0.0 2.7 2 1 0 2 2 2 0 NTPase AAA_19 PF13245.6 KIY52053.1 - 0.033 14.5 1.0 14 6.0 0.2 2.9 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KIY52053.1 - 0.033 14.0 0.0 5.4 6.8 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 KIY52053.1 - 0.035 13.0 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase IPT PF01745.16 KIY52053.1 - 0.051 12.9 0.0 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase PduV-EutP PF10662.9 KIY52053.1 - 0.054 13.2 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KIY52053.1 - 0.12 11.8 0.0 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit CPT PF07931.12 KIY52053.1 - 0.14 12.0 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MMR_HSR1 PF01926.23 KIY52053.1 - 0.14 12.2 0.1 7.4 6.7 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase F-box-like PF12937.7 KIY52055.1 - 1.3e-05 25.0 2.9 3.3e-05 23.7 0.1 3.0 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KIY52055.1 - 0.01 15.7 0.1 0.06 13.3 0.0 2.5 2 1 0 2 2 2 0 F-box domain Thioesterase PF00975.20 KIY52056.1 - 3.8e-10 40.3 0.0 6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Methyltransf_18 PF12847.7 KIY52058.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Hemerythrin PF01814.23 KIY52059.1 - 2.3e-10 41.2 3.9 3.3e-10 40.7 3.9 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Tox-ODYAM1 PF15642.6 KIY52059.1 - 0.0031 16.5 0.0 0.0043 16.1 0.0 1.1 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus KilA-N PF04383.13 KIY52060.1 - 0.05 13.4 0.2 0.52 10.2 0.2 2.1 1 1 0 1 1 1 0 KilA-N domain Hus1 PF04005.12 KIY52061.1 - 1.9e-71 240.6 0.0 2.1e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein PCI PF01399.27 KIY52062.1 - 5.6e-06 26.8 0.5 1.1e-05 25.8 0.2 1.6 2 0 0 2 2 2 1 PCI domain Cep57_MT_bd PF06657.13 KIY52062.1 - 0.027 14.9 0.6 0.073 13.5 0.6 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Maf PF02545.14 KIY52063.1 - 1.5e-43 148.5 0.0 1.9e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein DUF4012 PF13196.6 KIY52063.1 - 0.16 12.4 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) SPX PF03105.19 KIY52064.1 - 2.8e-35 123.0 0.1 5.5e-26 92.4 0.0 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 KIY52064.1 - 7.1e-23 81.4 29.0 7.2e-14 51.7 12.5 2.7 1 1 2 3 3 3 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KIY52064.1 - 3.8e-19 69.0 31.9 2.3e-11 43.5 12.3 3.1 1 1 1 2 2 2 2 Citrate transporter DUF4407 PF14362.6 KIY52064.1 - 0.013 14.9 0.1 0.032 13.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DinB PF05163.12 KIY52064.1 - 0.15 12.0 1.5 0.28 11.1 1.5 1.3 1 0 0 1 1 1 0 DinB family RRN3 PF05327.11 KIY52064.1 - 0.55 8.7 3.5 0.84 8.1 3.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.25 KIY52065.1 - 5.2e-18 65.3 0.0 6.6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52065.1 - 2.9e-08 33.3 0.0 4.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY52065.1 - 8.2e-08 31.4 0.0 1.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY52065.1 - 0.0001 22.3 0.2 0.14 12.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.16 KIY52065.1 - 0.017 15.3 0.1 0.053 13.7 0.1 1.8 2 0 0 2 2 2 0 ABC1 family R3H PF01424.22 KIY52066.1 - 4.8e-14 52.1 0.6 8.2e-14 51.3 0.6 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KIY52066.1 - 1.9e-06 27.8 47.7 0.00038 20.5 13.8 13.8 14 2 1 15 15 15 7 NF-X1 type zinc finger Isochorismatase PF00857.20 KIY52067.1 - 8.4e-17 61.9 0.0 1.4e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Herpes_U44 PF04533.13 KIY52067.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Herpes virus U44 protein Glutaredoxin PF00462.24 KIY52068.1 - 4.8e-20 71.5 0.0 4.8e-19 68.3 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KIY52068.1 - 3.6e-15 55.8 0.0 6.2e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIY52068.1 - 9e-05 22.7 0.0 0.048 14.0 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KIY52068.1 - 9.4e-05 22.8 0.0 0.00075 19.9 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 KIY52068.1 - 0.0014 18.6 0.3 0.027 14.4 0.0 2.6 1 1 1 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KIY52068.1 - 0.0047 16.9 0.1 0.04 14.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain CRISPR_Cse2 PF09485.10 KIY52068.1 - 0.067 13.7 0.0 0.24 11.9 0.0 1.9 2 1 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TrbC_Ftype PF09673.10 KIY52068.1 - 0.076 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein OST3_OST6 PF04756.13 KIY52068.1 - 0.22 10.8 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Dehydrin PF00257.19 KIY52071.1 - 0.12 13.0 2.6 0.16 12.5 2.6 1.2 1 0 0 1 1 1 0 Dehydrin WSC PF01822.19 KIY52072.1 - 1.3e-14 54.2 10.9 1.3e-14 54.2 10.9 1.8 2 1 0 2 2 2 1 WSC domain PAN_1 PF00024.26 KIY52072.1 - 0.012 15.6 2.3 0.18 11.8 0.6 2.5 1 1 1 2 2 2 0 PAN domain US10 PF17617.2 KIY52072.1 - 0.04 14.0 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral unique short region 10 BTB PF00651.31 KIY52073.1 - 0.00049 20.3 0.0 0.00099 19.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Fasciclin PF02469.22 KIY52074.1 - 7e-07 29.5 0.0 1.2e-06 28.8 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain BTB PF00651.31 KIY52075.1 - 0.00031 20.9 0.0 0.00055 20.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIY52077.1 - 1e-05 25.7 0.0 1.4e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 BTB/POZ domain Fasciclin PF02469.22 KIY52078.1 - 4.7e-08 33.3 0.0 7.8e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Fasciclin domain DUF4729 PF15866.5 KIY52079.1 - 0.0034 16.7 0.5 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4729) zf-Di19 PF05605.12 KIY52079.1 - 0.024 14.9 2.0 0.29 11.5 0.0 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KIY52079.1 - 0.059 13.1 9.2 0.34 10.7 2.5 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 KIY52079.1 - 0.083 13.0 0.3 0.15 12.2 0.3 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger zf-TAZ PF02135.16 KIY52079.1 - 4.5 7.8 12.3 1.6 9.3 5.2 2.3 1 1 1 2 2 2 0 TAZ zinc finger ChAPs PF09295.10 KIY52082.1 - 3.4e-05 23.0 0.0 3.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) Astro_capsid_p2 PF16580.5 KIY52083.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 C-terminal tail of astrovirus capsid projection or spike Adaptin_N PF01602.20 KIY52084.1 - 5.9e-69 233.0 0.7 7e-69 232.8 0.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIY52084.1 - 5.6e-14 52.5 1.1 5.8e-13 49.2 0.1 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIY52084.1 - 2.5e-05 24.2 1.9 0.76 10.2 0.1 4.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KIY52084.1 - 0.00013 22.3 0.5 0.00061 20.1 0.1 2.2 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KIY52084.1 - 0.0053 17.2 0.1 0.93 10.1 0.0 2.8 2 0 0 2 2 2 1 HEAT-like repeat Cohesin_HEAT PF12765.7 KIY52084.1 - 0.02 15.2 0.4 0.74 10.2 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Glyco_hydro_92N PF17678.1 KIY52086.1 - 1.3e-18 67.8 0.0 1.8e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_92 PF07971.12 KIY52086.1 - 1e-11 44.4 0.0 1.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 PAF PF15715.5 KIY52092.1 - 0.12 12.9 0.8 0.53 10.9 0.9 2.0 2 0 0 2 2 2 0 PCNA-associated factor histone like domain Pkinase PF00069.25 KIY52093.1 - 3e-08 33.4 0.0 4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52093.1 - 4.5e-05 22.9 0.0 6.2e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY52093.1 - 0.0019 18.2 0.0 0.0063 16.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Caudo_bapla16 PF16792.5 KIY52093.1 - 0.14 11.1 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Phage tail base-plate attachment protein of Caudovirales ORF16 KDZ PF18758.1 KIY52098.1 - 7.5e-16 58.4 0.3 8e-16 58.3 0.3 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Pfk_N PF18468.1 KIY52099.1 - 0.05 14.0 0.1 0.078 13.4 0.1 1.4 1 1 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast MuF_C PF18819.1 KIY52100.1 - 0.13 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage MuF-C-terminal domain BRAP2 PF07576.12 KIY52100.1 - 0.15 12.3 0.0 20 5.5 0.0 2.3 2 0 0 2 2 2 0 BRCA1-associated protein 2 gag-asp_proteas PF13975.6 KIY52103.1 - 0.0013 19.2 0.0 0.0089 16.6 0.0 2.3 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIY52103.1 - 0.07 12.9 0.1 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 Aspartyl protease Med31 PF05669.12 KIY52105.1 - 0.034 14.1 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 SOH1 HisKA_2 PF07568.12 KIY52105.1 - 0.049 13.7 0.5 0.088 12.9 0.5 1.4 1 1 0 1 1 1 0 Histidine kinase Plavaka PF18759.1 KIY52108.1 - 1.2e-94 317.2 1.2 1.8e-94 316.7 1.2 1.2 1 0 0 1 1 1 1 Plavaka transposase Phasin_2 PF09361.10 KIY52110.1 - 0.0042 17.3 3.1 0.011 16.0 3.1 1.6 1 0 0 1 1 1 1 Phasin protein AC_N PF16214.5 KIY52110.1 - 0.18 10.9 0.3 0.28 10.3 0.3 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region SlyX PF04102.12 KIY52112.1 - 0.00034 21.2 0.4 0.00078 20.0 0.4 1.6 1 0 0 1 1 1 1 SlyX DUF1806 PF08830.10 KIY52113.1 - 0.14 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1806) Prothymosin PF03247.14 KIY52114.1 - 0.4 11.2 9.6 0.68 10.4 9.6 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family gag-asp_proteas PF13975.6 KIY52116.1 - 1.4e-06 28.8 0.0 2.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY52116.1 - 0.0007 20.2 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease MAP65_ASE1 PF03999.12 KIY52120.1 - 9.4e-66 222.8 0.9 2.1e-60 205.1 0.0 2.4 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF3235 PF11574.8 KIY52120.1 - 0.11 13.4 0.0 0.32 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Flagellar_rod PF05149.12 KIY52120.1 - 0.47 9.9 12.3 0.089 12.2 2.4 3.2 3 1 0 3 3 3 0 Paraflagellar rod protein Helo_like_N PF17111.5 KIY52120.1 - 0.57 9.5 2.4 1.5 8.2 0.1 2.7 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Exonuc_VII_L PF02601.15 KIY52120.1 - 2.8 7.4 4.9 6.9 6.1 0.4 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Swi3 PF07962.12 KIY52121.1 - 5e-26 90.5 0.1 1e-25 89.5 0.1 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Gp_dh_C PF02800.20 KIY52122.1 - 6.9e-66 220.7 0.0 9.1e-66 220.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KIY52122.1 - 2.3e-20 72.8 0.1 9.7e-20 70.8 0.1 2.0 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Ribosomal_L24e PF01246.20 KIY52124.1 - 4.7e-30 103.6 0.2 4.7e-30 103.6 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e PI-PLC-X PF00388.19 KIY52125.1 - 0.00037 20.1 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Acetyltransf_1 PF00583.25 KIY52126.1 - 6.8e-10 39.2 0.0 8.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY52126.1 - 1.5e-08 34.9 0.0 2.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY52126.1 - 4.1e-07 30.0 0.0 5.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY52126.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Mo25 PF08569.11 KIY52127.1 - 1.4e-127 425.6 2.1 1.6e-127 425.4 2.1 1.0 1 0 0 1 1 1 1 Mo25-like Spore_GerQ PF09671.10 KIY52127.1 - 0.019 15.0 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) Lipocalin_7 PF14651.6 KIY52127.1 - 0.11 12.5 0.2 0.36 10.8 0.1 1.8 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family TFCD_C PF12612.8 KIY52127.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal WD40 PF00400.32 KIY52128.1 - 4.8e-10 39.9 10.2 3.5e-05 24.5 0.0 4.5 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY52128.1 - 0.00014 22.1 0.0 0.00079 19.7 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIY52128.1 - 0.004 16.9 1.4 0.004 16.9 1.4 2.0 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.12 KIY52128.1 - 3.5 7.7 6.1 3.6 7.6 0.0 3.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Lactonase PF10282.9 KIY52129.1 - 1.4e-29 103.4 0.0 1.7e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.21 KIY52130.1 - 4.9e-08 32.6 0.2 2.8e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 Dioxygenase Pkinase PF00069.25 KIY52131.1 - 3.6e-71 239.6 0.0 4.2e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52131.1 - 3.1e-41 141.4 0.0 3.8e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY52131.1 - 1.6e-13 50.7 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY52131.1 - 0.00048 19.5 0.3 0.0009 18.6 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY52131.1 - 0.024 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIY52131.1 - 0.038 13.9 0.5 0.13 12.2 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Synaptobrevin PF00957.21 KIY52132.1 - 1.2e-34 117.9 2.2 1.4e-34 117.7 2.2 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF515 PF04415.12 KIY52132.1 - 0.016 13.6 0.6 0.019 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2970 PF11174.8 KIY52132.1 - 0.023 14.5 1.3 0.039 13.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Peptidase_M48_N PF16491.5 KIY52132.1 - 0.059 13.3 0.6 0.077 12.9 0.6 1.1 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices FeoB_associated PF12669.7 KIY52132.1 - 8 7.0 11.5 12 6.4 11.5 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Glyco_hydro_88 PF07470.13 KIY52133.1 - 2.2e-23 82.9 0.9 5.1e-15 55.4 0.1 2.0 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_92 PF07971.12 KIY52134.1 - 3.5e-114 382.3 0.0 4.2e-114 382.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIY52134.1 - 3.1e-35 122.2 1.0 5.5e-35 121.4 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain RA PF00788.23 KIY52135.1 - 1.7e-12 47.8 0.0 1.1e-09 38.8 0.0 3.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 KIY52135.1 - 8.4e-06 25.3 0.1 2.3e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KIY52135.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SID-1_RNA_chan PF13965.6 KIY52135.1 - 1.4 7.2 13.0 2.7 6.3 13.0 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDRGK PF09756.9 KIY52135.1 - 1.7 8.2 40.6 0.26 10.9 34.9 2.4 2 0 0 2 2 2 0 DDRGK domain Folate_carrier PF01770.18 KIY52135.1 - 2.3 6.9 11.9 4.2 6.0 11.9 1.4 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 KIY52135.1 - 9.2 4.4 8.0 18 3.5 8.0 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EF-hand_1 PF00036.32 KIY52136.1 - 2.6e-40 133.0 9.5 4.2e-10 38.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIY52136.1 - 6e-34 116.3 2.6 2.5e-16 59.9 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY52136.1 - 3.4e-29 98.3 4.0 2.2e-09 36.5 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KIY52136.1 - 4.9e-29 99.9 8.5 2.6e-13 49.6 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KIY52136.1 - 1.3e-26 90.8 4.3 1.5e-06 27.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KIY52136.1 - 1.1e-16 60.9 0.2 2.2e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KIY52136.1 - 4.9e-08 32.9 0.9 0.0015 18.4 0.1 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIY52136.1 - 4e-07 30.4 0.0 0.028 14.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KIY52136.1 - 1.2e-06 28.4 0.0 0.041 13.9 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KIY52136.1 - 0.00016 21.7 0.5 0.00046 20.2 0.1 1.9 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KIY52136.1 - 0.00018 21.6 5.5 0.017 15.3 0.6 3.0 1 1 2 3 3 3 2 Dockerin type I domain EF-hand_11 PF08976.11 KIY52136.1 - 0.00044 21.1 0.0 0.27 12.1 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Caleosin PF05042.13 KIY52136.1 - 0.00099 19.1 0.3 0.52 10.2 0.0 3.1 1 1 2 3 3 3 1 Caleosin related protein Poly_export PF02563.16 KIY52136.1 - 0.0017 18.6 0.1 0.63 10.3 0.0 3.0 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein DUF1103 PF06513.11 KIY52136.1 - 0.0018 18.0 1.5 0.0021 17.7 1.5 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.13 KIY52136.1 - 0.0035 17.3 0.2 0.47 10.4 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB SurA_N_2 PF13623.6 KIY52136.1 - 0.0083 16.0 0.3 0.52 10.2 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KIY52136.1 - 0.01 16.1 0.1 6.3 7.2 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 KIY52136.1 - 0.011 15.5 0.2 0.037 13.8 0.2 1.8 1 1 0 1 1 1 0 SurA N-terminal domain DUF4497 PF14924.6 KIY52136.1 - 0.012 16.0 0.0 1 9.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 KIY52136.1 - 0.012 15.9 0.9 5.6 7.3 0.1 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 MotA_activ PF09114.10 KIY52136.1 - 0.017 15.2 0.3 0.31 11.2 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain p25-alpha PF05517.12 KIY52136.1 - 0.031 14.4 0.1 7.2 6.8 0.1 2.5 1 1 1 2 2 2 0 p25-alpha DUF1811 PF08838.10 KIY52136.1 - 0.047 13.9 0.1 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Fe_hyd_lg_C PF02906.14 KIY52136.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RuvA_C PF07499.13 KIY52136.1 - 0.14 12.6 0.0 9.3 6.8 0.0 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain Dynamin_N PF00350.23 KIY52137.1 - 7.8e-42 143.2 0.0 1.9e-41 141.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KIY52137.1 - 5e-13 48.9 0.0 4.3e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KIY52137.1 - 0.00019 21.5 0.0 0.00071 19.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KIY52137.1 - 0.082 13.1 0.2 3.2 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIY52137.1 - 0.2 11.9 0.0 0.79 9.9 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase YtxH PF12732.7 KIY52137.1 - 6.5 7.4 5.6 22 5.7 0.1 3.3 3 1 1 4 4 4 0 YtxH-like protein DEAD PF00270.29 KIY52138.1 - 9.2e-53 178.6 0.0 2.1e-51 174.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY52138.1 - 4.6e-32 110.7 0.0 6.8e-31 106.9 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY52138.1 - 7.3e-08 32.6 0.0 3e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KIY52138.1 - 0.015 14.1 0.0 0.12 11.1 0.0 2.4 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 GRP PF07172.11 KIY52138.1 - 0.081 13.6 27.5 0.19 12.4 27.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family AAA PF00004.29 KIY52138.1 - 0.15 12.5 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-RING_2 PF13639.6 KIY52139.1 - 0.03 14.6 16.4 0.03 14.6 16.4 2.3 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 KIY52139.1 - 0.17 11.8 16.6 0.45 10.4 16.6 1.7 1 1 0 1 1 1 0 PHD-finger DIOX_N PF14226.6 KIY52141.1 - 1e-13 52.0 0.0 1.9e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY52141.1 - 3.3e-09 37.1 0.1 9.7e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AIRC PF00731.20 KIY52142.1 - 6.6e-61 204.2 0.5 6.6e-61 204.2 0.5 1.8 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KIY52142.1 - 3.3e-53 179.8 0.0 5e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KIY52142.1 - 4.9e-19 67.8 0.1 9.4e-19 66.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KIY52142.1 - 0.0045 16.5 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KIY52142.1 - 0.037 13.6 0.0 0.069 12.7 0.0 1.5 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 KIY52142.1 - 0.049 13.2 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Propionate catabolism activator ANAPC10 PF03256.16 KIY52143.1 - 6.8e-40 136.7 0.0 8.1e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KIY52143.1 - 0.027 14.6 0.0 0.069 13.3 0.0 1.7 1 1 1 2 2 2 0 F5/8 type C domain PPR_2 PF13041.6 KIY52145.1 - 0.011 15.9 0.1 7.1 6.9 0.0 3.6 3 0 0 3 3 3 0 PPR repeat family eIF-5_eIF-2B PF01873.17 KIY52146.1 - 2e-41 140.5 0.1 2.7e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KIY52146.1 - 0.003 17.0 0.1 0.0051 16.3 0.1 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding zf-HYPF PF07503.12 KIY52146.1 - 0.013 15.3 0.2 7.2 6.5 0.0 2.8 2 0 0 2 2 2 0 HypF finger Herpes_ori_bp PF02399.15 KIY52146.1 - 0.016 13.3 0.0 0.022 12.8 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Arc_trans_TRASH PF08394.10 KIY52146.1 - 0.023 15.0 0.9 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Archaeal TRASH domain IF2_N PF04760.15 KIY52146.1 - 0.045 13.6 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region EF-hand_1 PF00036.32 KIY52148.1 - 8.8e-35 115.7 11.0 4.3e-09 35.3 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIY52148.1 - 1.3e-29 102.4 2.1 1.5e-17 63.8 0.4 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY52148.1 - 9.8e-26 87.5 9.2 1.2e-08 34.2 0.6 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KIY52148.1 - 1.9e-25 88.5 10.5 2.5e-14 52.8 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KIY52148.1 - 2.4e-23 80.5 11.7 5.1e-07 28.9 0.5 5.0 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 KIY52148.1 - 3.8e-13 49.6 0.1 4.6e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 KIY52148.1 - 1.8e-07 31.0 0.0 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 KIY52148.1 - 8.4e-07 28.9 2.4 0.0097 15.9 1.0 3.0 2 2 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIY52148.1 - 6.3e-06 26.5 0.1 0.0056 17.0 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KIY52148.1 - 0.00039 20.6 0.6 1.4 9.2 0.0 2.8 2 1 0 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 KIY52148.1 - 0.00086 19.3 0.3 0.94 9.4 0.5 3.0 1 1 1 2 2 2 2 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KIY52148.1 - 0.001 19.4 1.4 1.3 9.3 0.1 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb4 TerB PF05099.13 KIY52148.1 - 0.007 16.3 0.1 3.9 7.4 0.0 2.3 1 1 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_11 PF08976.11 KIY52148.1 - 0.018 15.9 0.0 4.3 8.3 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain NIR_SIR_ferr PF03460.17 KIY52148.1 - 0.075 12.9 0.2 0.99 9.3 0.0 2.6 2 1 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain DUF3670 PF12419.8 KIY52148.1 - 0.082 12.8 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 SNF2 Helicase protein Sugar_tr PF00083.24 KIY52149.1 - 1.5e-44 152.7 20.8 2e-44 152.2 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY52149.1 - 2.3e-21 76.1 27.1 2.8e-14 52.8 6.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aconitase PF00330.20 KIY52150.1 - 3.1e-150 501.2 0.1 3.8e-150 500.9 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIY52150.1 - 1.2e-44 151.8 0.0 2.3e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain WH1 PF00568.23 KIY52152.1 - 3.5e-22 78.4 0.0 5.1e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KIY52152.1 - 5.5e-06 26.6 0.1 5.5e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain WH2 PF02205.20 KIY52152.1 - 0.0016 18.2 0.1 0.0046 16.7 0.1 1.8 1 0 0 1 1 1 1 WH2 motif AMP-binding PF00501.28 KIY52153.1 - 3.8e-48 164.1 0.0 3.1e-30 105.1 0.0 2.9 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KIY52153.1 - 1.8e-13 51.2 0.6 2.6e-12 47.5 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Cyt-b5 PF00173.28 KIY52154.1 - 9e-13 48.2 0.0 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1634 PF07843.11 KIY52154.1 - 0.23 11.5 1.7 0.64 10.1 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DAO PF01266.24 KIY52156.1 - 9.2e-35 120.9 1.9 1.4e-34 120.2 1.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY52156.1 - 9.6e-05 22.5 0.0 0.00055 20.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY52156.1 - 0.013 14.8 0.0 0.5 9.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY52156.1 - 0.026 14.5 0.0 0.086 12.8 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KIY52156.1 - 0.19 11.0 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family L51_S25_CI-B8 PF05047.16 KIY52158.1 - 3.9e-11 42.7 0.0 5.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RGS PF00615.19 KIY52159.1 - 2e-08 34.5 2.2 0.0019 18.5 0.6 2.9 2 1 0 2 2 2 2 Regulator of G protein signaling domain Fox-1_C PF12414.8 KIY52159.1 - 0.049 14.0 0.2 0.26 11.7 0.1 2.1 2 0 0 2 2 2 0 Calcitonin gene-related peptide regulator C terminal Mucin PF01456.17 KIY52160.1 - 0.0057 16.6 5.2 0.03 14.3 0.4 2.5 2 0 0 2 2 2 2 Mucin-like glycoprotein MecA PF05389.12 KIY52160.1 - 0.12 12.0 5.1 0.78 9.3 5.1 2.1 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) Vfa1 PF08432.10 KIY52160.1 - 3.4 7.9 18.2 0.23 11.8 12.3 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HMG_box PF00505.19 KIY52161.1 - 9.4e-15 54.8 6.5 7.2e-08 32.7 3.5 3.0 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY52161.1 - 8.6e-06 26.3 7.7 0.0016 19.0 0.2 2.9 3 0 0 3 3 3 2 HMG-box domain TFIIA_gamma_N PF02268.16 KIY52163.1 - 0.14 12.2 0.5 24 5.0 0.1 2.5 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain TIR_3 PF18567.1 KIY52163.1 - 0.99 9.4 7.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Toll/interleukin-1 receptor domain Ribosomal_L14 PF00238.19 KIY52164.1 - 1.9e-45 153.9 2.1 2.3e-45 153.6 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PknH_C PF14032.6 KIY52165.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 PknH-like extracellular domain Ferric_reduct PF01794.19 KIY52167.1 - 6.9e-18 65.0 6.1 6.9e-18 65.0 6.1 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIY52167.1 - 7.1e-14 51.8 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KIY52167.1 - 8.5e-13 48.7 0.0 1.2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KIY52167.1 - 0.048 14.3 0.0 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain EPL1 PF10513.9 KIY52168.1 - 1.7e-21 77.2 0.1 1.7e-21 77.2 0.1 2.3 3 1 0 3 3 3 1 Enhancer of polycomb-like GlyL_C PF12524.8 KIY52168.1 - 0.16 12.1 0.9 14 5.9 0.1 3.1 2 0 0 2 2 2 0 dsDNA virus glycoprotein L C terminal SOXp PF12336.8 KIY52168.1 - 3.8 8.6 6.7 2.1 9.4 0.8 2.9 2 0 0 2 2 2 0 SOX transcription factor S4 PF01479.25 KIY52169.1 - 1.4e-10 40.7 0.0 3.8e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KIY52169.1 - 0.22 11.3 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 S4 domain DUF3669 PF12417.8 KIY52170.1 - 1.9e-12 47.2 0.1 3.7e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Zinc finger protein PQ-loop PF04193.14 KIY52171.1 - 8.3e-16 57.5 6.3 2.1e-10 40.2 0.4 3.7 4 0 0 4 4 4 2 PQ loop repeat Syndecan PF01034.20 KIY52171.1 - 4 7.4 5.0 6.9 6.7 0.4 3.4 4 0 0 4 4 4 0 Syndecan domain DIOX_N PF14226.6 KIY52172.1 - 2.2e-21 76.8 0.8 9.8e-21 74.7 0.0 2.3 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY52172.1 - 3.1e-11 43.7 0.0 7.3e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPT_ssu-like PF11779.8 KIY52173.1 - 5.3e-12 45.2 4.1 7.1e-12 44.8 4.1 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Pyr_redox_2 PF07992.14 KIY52174.1 - 6.4e-50 170.1 0.0 7.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY52174.1 - 2.4e-09 37.6 0.0 1.8e-08 34.8 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY52174.1 - 0.02 14.1 0.0 4.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY52174.1 - 0.1 13.1 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF4398 PF14346.6 KIY52174.1 - 0.34 11.5 3.1 0.56 10.9 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) EPSP_synthase PF00275.20 KIY52176.1 - 3.4e-119 398.3 0.1 7e-119 397.2 0.0 1.6 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KIY52176.1 - 1.5e-101 339.0 0.0 1.8e-100 335.4 0.0 2.2 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KIY52176.1 - 5.2e-52 177.4 0.0 1.3e-51 176.1 0.0 1.7 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 KIY52176.1 - 3.6e-30 105.2 0.0 4.3e-29 101.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KIY52176.1 - 1.4e-25 89.4 0.0 4.2e-25 87.8 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KIY52176.1 - 4e-08 32.9 0.2 1.2e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 KIY52176.1 - 2.7e-07 30.6 0.1 8.7e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KIY52176.1 - 5.3e-07 29.8 0.0 1.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KIY52176.1 - 0.03 14.5 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sacchrp_dh_NADP PF03435.18 KIY52176.1 - 0.043 14.1 0.0 2.3 8.5 0.0 3.1 4 0 0 4 4 4 0 Saccharopine dehydrogenase NADP binding domain Rib_5-P_isom_A PF06026.14 KIY52177.1 - 7.8e-60 201.4 0.0 9.8e-60 201.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Tfb5 PF06331.12 KIY52178.1 - 4.4e-16 58.6 0.8 4.8e-16 58.5 0.8 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Copper-fist PF00649.18 KIY52179.1 - 2.2e-15 55.9 0.7 2.2e-15 55.9 0.7 2.1 1 1 1 2 2 2 1 Copper fist DNA binding domain Wzy_C PF04932.15 KIY52180.1 - 0.17 11.5 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase CUE PF02845.16 KIY52181.1 - 3.5e-10 39.4 0.0 5.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain Dehalogenase PF13486.6 KIY52181.1 - 0.04 13.3 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit Methyltransf_32 PF13679.6 KIY52182.1 - 7.5e-23 81.3 0.0 1.3e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY52182.1 - 0.0082 16.8 0.0 0.018 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 KIY52182.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase TRM13 MTS PF05175.14 KIY52182.1 - 0.026 14.0 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 KIY52182.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.20 KIY52182.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCRF PF03462.18 KIY52183.1 - 1.1e-38 133.0 0.0 4.4e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KIY52183.1 - 1.7e-36 124.6 1.5 2.9e-36 123.9 1.5 1.3 1 0 0 1 1 1 1 RF-1 domain YkuI_C PF10388.9 KIY52183.1 - 0.008 16.0 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 1 EAL-domain associated signalling protein domain Aldo_ket_red PF00248.21 KIY52184.1 - 8.6e-38 130.2 0.0 1.2e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M20 PF01546.28 KIY52185.1 - 1.3e-29 103.4 0.0 2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY52185.1 - 5.5e-12 45.6 0.0 1.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY52185.1 - 0.00084 19.1 0.0 0.0019 17.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 DUF2968 PF11180.8 KIY52186.1 - 0.034 13.8 0.6 0.054 13.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) PGBA_C PF15437.6 KIY52186.1 - 0.18 12.2 5.7 3.2 8.2 1.2 2.4 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Macoilin PF09726.9 KIY52186.1 - 7.5 5.0 18.2 8.7 4.8 15.6 2.1 1 1 1 2 2 2 0 Macoilin family Fer2 PF00111.27 KIY52187.1 - 3.6e-11 42.8 0.1 5.3e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 KIY52187.1 - 0.1 12.2 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Magnetochrome domain RTP1_C2 PF10304.9 KIY52187.1 - 0.25 11.1 0.9 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 GCP_N_terminal PF17681.1 KIY52188.1 - 8.2e-63 212.8 0.0 2.2e-62 211.4 0.0 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIY52188.1 - 2.7e-58 197.9 8.6 2.7e-58 197.9 8.6 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Aminotran_1_2 PF00155.21 KIY52189.1 - 2.8e-37 128.7 0.0 3.9e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Paf67 PF10255.9 KIY52190.1 - 4.5e-163 543.0 0.0 8.4e-163 542.1 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KIY52190.1 - 0.055 13.6 0.2 0.39 10.9 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat APH PF01636.23 KIY52191.1 - 3.1e-07 30.6 3.7 4.8e-05 23.4 0.0 3.2 2 1 2 4 4 4 2 Phosphotransferase enzyme family RIO1 PF01163.22 KIY52191.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family ATG22 PF11700.8 KIY52192.1 - 1e-110 370.6 15.7 1.2e-110 370.4 15.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KIY52192.1 - 1.2e-11 44.2 34.1 5.5e-09 35.4 7.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.9 KIY52192.1 - 0.0012 18.5 2.9 0.0019 17.9 2.9 1.3 1 0 0 1 1 1 1 Short C-terminal domain FHA PF00498.26 KIY52193.1 - 1.1e-06 28.9 0.0 2.1e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIY52193.1 - 0.00091 19.5 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain JHBP PF06585.11 KIY52193.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF35_N PF12172.8 KIY52193.1 - 0.19 11.6 0.1 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) SNARE PF05739.19 KIY52194.1 - 3.6e-08 33.3 0.4 7.6e-08 32.2 0.4 1.5 1 0 0 1 1 1 1 SNARE domain Tropomyosin PF00261.20 KIY52194.1 - 0.075 12.4 0.4 0.1 12.0 0.4 1.1 1 0 0 1 1 1 0 Tropomyosin Glyco_hyd_65N_2 PF14498.6 KIY52195.1 - 2.6e-46 158.4 0.0 3.8e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.18 KIY52196.1 - 7.3e-95 318.0 0.9 2.3e-92 309.8 0.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Pkinase PF00069.25 KIY52197.1 - 7.3e-71 238.6 0.0 9.2e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52197.1 - 2.5e-34 118.7 0.0 3.4e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIY52197.1 - 6.9e-12 45.9 2.8 1.7e-11 44.7 2.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KIY52197.1 - 3.1e-05 23.1 0.0 4.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY52197.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIY52197.1 - 0.039 13.6 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY52197.1 - 0.067 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.30 KIY52197.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 C2 domain Ham1p_like PF01725.16 KIY52198.1 - 2.7e-55 187.2 0.0 3.1e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Metallopep PF12044.8 KIY52198.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Mss4 PF04421.13 KIY52199.1 - 2.1e-16 59.8 0.0 2.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_1 PF00583.25 KIY52200.1 - 3.4e-12 46.6 0.0 4.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY52200.1 - 9.8e-10 38.5 0.0 1.3e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY52200.1 - 5.6e-07 29.9 0.0 7.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY52200.1 - 0.00021 21.4 0.0 0.0003 20.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIY52200.1 - 0.013 15.5 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 KIY52200.1 - 0.044 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 KIY52200.1 - 0.13 11.7 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Glyco_hydro_38N PF01074.22 KIY52201.1 - 6.5e-76 255.4 0.3 1.1e-75 254.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KIY52201.1 - 9.5e-48 163.1 0.0 1.6e-47 162.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KIY52201.1 - 9.4e-20 70.6 0.0 2.1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KIY52201.1 - 1.4e-08 34.7 0.0 2.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KIY52201.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Adap_comp_sub PF00928.21 KIY52202.1 - 2e-91 306.0 0.0 3.9e-91 305.1 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIY52202.1 - 4.4e-07 29.9 0.5 7.6e-07 29.2 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.22 KIY52203.1 - 4.4e-16 58.5 0.0 6.8e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KIY52203.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 RL domain Nup35_RRM_2 PF14605.6 KIY52203.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KIY52203.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif Ribosomal_L14 PF00238.19 KIY52204.1 - 3.5e-34 117.5 0.0 4.2e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Tetraspanin PF00335.20 KIY52205.1 - 0.11 12.2 13.8 0.52 10.0 13.8 1.9 1 1 0 1 1 1 0 Tetraspanin family MARVEL PF01284.23 KIY52205.1 - 0.11 12.5 12.1 0.22 11.5 11.6 1.8 1 1 0 1 1 1 0 Membrane-associating domain Peptidase_M50 PF02163.22 KIY52206.1 - 1.4e-18 67.1 0.0 6.8e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Peptidase family M50 Cupin_5 PF06172.11 KIY52207.1 - 5.1e-26 91.5 0.0 6.4e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Synaptobrevin PF00957.21 KIY52208.1 - 2.5e-15 56.0 1.0 4.1e-15 55.3 1.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KIY52208.1 - 1.8e-06 27.9 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain An_peroxidase PF03098.15 KIY52209.1 - 4.8e-35 121.1 0.0 2.7e-25 89.0 0.0 3.3 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KIY52209.1 - 0.034 12.9 0.0 0.076 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome P450 Glyco_trans_2_3 PF13632.6 KIY52210.1 - 2.4e-57 194.1 1.9 2.4e-57 194.1 1.9 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KIY52210.1 - 2.3e-05 24.3 0.0 0.00073 19.4 0.0 2.8 3 1 0 3 3 3 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIY52210.1 - 3.4e-05 23.8 0.1 6.2e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIY52210.1 - 0.011 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 Filament PF00038.21 KIY52211.1 - 0.0016 18.1 7.2 0.0044 16.7 7.2 1.6 1 1 0 1 1 1 1 Intermediate filament protein Tho2 PF11262.8 KIY52211.1 - 0.0019 17.5 2.3 0.0022 17.3 2.3 1.0 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Nup54_57_C PF18570.1 KIY52211.1 - 0.003 17.1 0.7 0.02 14.5 0.1 2.5 3 0 0 3 3 3 1 NUP57/Nup54 C-terminal domain DUF4482 PF14818.6 KIY52211.1 - 0.0036 18.2 2.0 0.0044 17.9 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4482) CLZ PF16526.5 KIY52211.1 - 0.0041 17.5 6.8 0.41 11.0 1.0 2.0 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BRE1 PF08647.11 KIY52211.1 - 0.0064 16.5 5.7 0.0079 16.2 5.7 1.1 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 KIY52211.1 - 0.0069 16.9 5.1 0.0076 16.7 5.1 1.0 1 0 0 1 1 1 1 Fez1 DHR10 PF18595.1 KIY52211.1 - 0.0073 16.4 6.9 0.0097 16.0 6.9 1.2 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain APG6_N PF17675.1 KIY52211.1 - 0.0076 16.8 10.1 0.0094 16.5 10.1 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Uso1_p115_C PF04871.13 KIY52211.1 - 0.0099 16.2 8.4 0.012 16.0 8.4 1.0 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region ERM PF00769.19 KIY52211.1 - 0.011 15.6 11.5 0.012 15.5 11.5 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.8 KIY52211.1 - 0.012 15.7 7.1 0.013 15.5 7.1 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 KIY52211.1 - 0.015 15.7 5.1 0.021 15.2 5.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 KIY52211.1 - 0.015 14.2 3.3 0.017 14.0 3.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HMMR_N PF15905.5 KIY52211.1 - 0.016 14.7 3.8 0.019 14.4 3.8 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 KIY52211.1 - 0.018 15.3 0.6 0.021 15.0 0.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TSNAXIP1_N PF15739.5 KIY52211.1 - 0.019 15.3 5.2 0.024 15.0 5.2 1.1 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF3450 PF11932.8 KIY52211.1 - 0.022 14.1 4.5 0.025 13.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Taxilin PF09728.9 KIY52211.1 - 0.028 13.6 7.5 0.032 13.4 7.5 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein HOOK PF05622.12 KIY52211.1 - 0.033 12.4 6.0 0.038 12.1 6.0 1.1 1 0 0 1 1 1 0 HOOK protein DUF1640 PF07798.11 KIY52211.1 - 0.038 14.0 2.9 0.052 13.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GAS PF13851.6 KIY52211.1 - 0.079 12.3 6.4 0.1 11.9 6.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 KIY52211.1 - 0.081 11.6 1.9 0.084 11.5 1.9 1.0 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 KIY52211.1 - 0.084 12.7 4.3 0.096 12.5 4.3 1.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF724 PF05266.14 KIY52211.1 - 0.088 12.6 3.8 0.1 12.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GPS2_interact PF15784.5 KIY52211.1 - 0.09 13.2 4.6 0.095 13.2 3.8 1.4 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Rabaptin PF03528.15 KIY52211.1 - 0.095 11.4 6.4 0.11 11.2 6.4 1.0 1 0 0 1 1 1 0 Rabaptin FapA PF03961.13 KIY52211.1 - 0.1 11.2 2.4 0.11 11.1 2.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Golgin_A5 PF09787.9 KIY52211.1 - 0.17 11.3 6.4 0.2 11.1 6.4 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 KIY52211.1 - 0.18 11.9 10.7 1.4 9.0 0.8 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Herpes_UL6 PF01763.16 KIY52211.1 - 0.19 10.2 2.9 0.21 10.0 2.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Nas2_N PF18265.1 KIY52211.1 - 0.19 11.6 3.2 2 8.4 0.4 2.4 1 1 0 2 2 2 0 Nas2 N_terminal domain Myosin_tail_1 PF01576.19 KIY52211.1 - 0.2 9.4 10.4 0.23 9.2 10.4 1.0 1 0 0 1 1 1 0 Myosin tail Spc24 PF08286.11 KIY52211.1 - 0.23 11.7 7.6 0.62 10.3 3.9 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SYCE1 PF15233.6 KIY52211.1 - 0.27 11.3 8.2 0.85 9.7 2.9 2.0 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF4200 PF13863.6 KIY52211.1 - 0.36 11.2 9.9 6.4 7.2 9.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Prefoldin PF02996.17 KIY52211.1 - 0.37 10.7 6.2 0.97 9.4 1.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit EzrA PF06160.12 KIY52211.1 - 0.41 8.8 7.8 0.48 8.5 7.8 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Prefoldin_2 PF01920.20 KIY52211.1 - 0.41 10.6 8.6 0.29 11.1 2.4 2.0 1 1 1 2 2 2 0 Prefoldin subunit Ax_dynein_light PF10211.9 KIY52211.1 - 0.43 10.5 7.2 0.56 10.1 7.2 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain TMPIT PF07851.13 KIY52211.1 - 0.49 9.6 1.1 0.51 9.5 1.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF5082 PF16888.5 KIY52211.1 - 0.5 10.6 8.8 2.7 8.3 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) FUSC PF04632.12 KIY52211.1 - 0.62 8.5 2.6 0.6 8.6 2.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KIY52211.1 - 1.1 8.6 4.1 1.2 8.4 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 KIY52211.1 - 1.7 8.9 5.4 11 6.3 1.4 2.1 1 1 1 2 2 2 0 Haemolysin XhlA TMF_DNA_bd PF12329.8 KIY52211.1 - 1.8 8.6 11.7 6.2 6.9 3.9 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KIY52211.1 - 2.3 8.7 10.9 3.2 8.3 10.9 1.3 1 0 0 1 1 1 0 Cell division protein ZapB GrpE PF01025.19 KIY52211.1 - 4.4 6.9 8.5 7.7 6.1 8.5 1.5 1 1 0 1 1 1 0 GrpE CCDC-167 PF15188.6 KIY52211.1 - 5.4 7.4 9.8 8.2 6.9 9.8 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF5320 PF17253.2 KIY52211.1 - 6.5 7.9 7.5 27 5.9 1.9 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF4140 PF13600.6 KIY52211.1 - 7.3 7.1 10.2 1.8e+02 2.7 10.2 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Cullin PF00888.22 KIY52212.1 - 0.00043 19.0 0.0 0.00053 18.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family DUF3597 PF12200.8 KIY52212.1 - 0.039 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF4449 PF14613.6 KIY52213.1 - 1.7e-32 112.8 0.1 1.7e-32 112.8 0.1 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) Herpes_pp85 PF04637.12 KIY52213.1 - 0.029 12.8 0.0 0.065 11.6 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DegS PF05384.11 KIY52213.1 - 0.16 11.4 2.8 0.23 10.9 0.9 2.2 2 0 0 2 2 2 0 Sensor protein DegS Ribosomal_L38e PF01781.18 KIY52214.1 - 3.8e-31 107.0 1.2 4.1e-31 106.9 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Linker_histone PF00538.19 KIY52214.1 - 0.013 15.8 0.3 0.018 15.4 0.3 1.2 1 0 0 1 1 1 0 linker histone H1 and H5 family P-II PF00543.22 KIY52215.1 - 0.0066 17.0 0.0 7.9 7.2 0.0 2.6 2 0 0 2 2 2 2 Nitrogen regulatory protein P-II DUF4530 PF15039.6 KIY52215.1 - 0.012 15.7 0.1 0.87 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) IFR3_antag PF14754.6 KIY52215.1 - 0.092 11.9 0.0 2.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Papain-like auto-proteinase Exo_endo_phos PF03372.23 KIY52217.1 - 5.2e-05 22.9 0.0 8.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 KIY52218.1 - 4.6e-06 26.3 0.0 2.2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_Mu_Gam PF07352.12 KIY52218.1 - 0.0019 18.1 0.0 0.0051 16.7 0.0 1.7 2 0 0 2 2 2 1 Bacteriophage Mu Gam like protein zf-RVT PF13966.6 KIY52219.1 - 7.2e-06 26.6 0.4 7.2e-06 26.6 0.4 2.4 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase Sulfate_transp PF00916.20 KIY52222.1 - 1.3e-82 277.6 15.9 1.3e-82 277.6 15.9 1.3 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KIY52222.1 - 1.1e-12 47.7 0.0 1.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain Palm_thioest PF02089.15 KIY52223.1 - 0.00099 19.0 0.0 0.0022 17.9 0.0 1.5 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KIY52223.1 - 0.0033 17.0 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KIY52223.1 - 0.045 13.4 0.1 0.24 11.0 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KIY52223.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PET117 PF15786.5 KIY52223.1 - 9.5 6.6 6.1 1.2 9.5 0.4 2.1 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial PhzC-PhzF PF02567.16 KIY52224.1 - 2.3e-32 112.6 0.1 3.6e-32 112.0 0.1 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Glyco_hydro_18 PF00704.28 KIY52226.1 - 4.5e-55 187.6 0.0 5.6e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.24 KIY52226.1 - 1e-09 38.4 0.0 1.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 PX domain Tannase PF07519.11 KIY52227.1 - 1.5e-137 459.3 3.9 1.8e-137 459.1 3.9 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Tannase PF07519.11 KIY52228.1 - 2.6e-05 23.3 0.0 2.7e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase IDO PF01231.18 KIY52230.1 - 4.6e-137 457.3 0.0 5.3e-137 457.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase XAP5 PF04921.14 KIY52231.1 - 2.9e-88 295.9 2.5 2.9e-88 295.9 2.5 2.3 1 1 0 2 2 2 1 XAP5, circadian clock regulator RuBisCO_small PF00101.20 KIY52231.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain NDUF_B6 PF09782.9 KIY52231.1 - 0.12 12.5 0.7 0.29 11.3 0.7 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF4964 PF16334.5 KIY52232.1 - 0.19 11.3 1.2 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4964) TDA11 PF17084.5 KIY52232.1 - 0.22 10.4 0.2 0.24 10.3 0.2 1.1 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 DUF4710 PF15828.5 KIY52234.1 - 0.5 10.5 5.0 1.3 9.2 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4710) MRPL52 PF18699.1 KIY52234.1 - 0.71 10.1 7.1 13 6.0 0.0 3.0 2 1 1 3 3 3 0 Mitoribosomal protein mL52 MCPVI PF02993.14 KIY52234.1 - 2.4 8.0 6.0 0.83 9.4 1.8 2.2 2 1 1 3 3 3 0 Minor capsid protein VI DDE_1 PF03184.19 KIY52235.1 - 4.1e-22 78.7 0.0 1.1e-21 77.2 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIY52235.1 - 0.001 18.9 0.0 0.0032 17.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease ELMO_CED12 PF04727.13 KIY52235.1 - 0.074 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 ELMO/CED-12 family NUDIX PF00293.28 KIY52237.1 - 2.3e-16 60.0 0.0 3.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KIY52237.1 - 8.9e-11 42.4 0.0 2.2e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KIY52237.1 - 3.5e-05 23.4 0.2 7.6e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF659 PF04937.15 KIY52238.1 - 1.1e-08 35.1 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KIY52238.1 - 0.0085 15.9 0.1 0.021 14.6 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RAP1 PF07218.11 KIY52238.1 - 4.1 5.6 5.1 11 4.1 5.1 1.6 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NUDIX PF00293.28 KIY52240.1 - 1.1e-16 61.1 0.0 1.8e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KIY52240.1 - 3.3e-10 40.5 0.1 7.7e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KIY52240.1 - 3.6e-05 23.3 0.2 7.7e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Pkinase PF00069.25 KIY52241.1 - 1.9e-19 70.1 0.0 2e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52241.1 - 3.6e-06 26.4 0.0 3.9e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY52241.1 - 3e-05 23.5 0.0 3.4e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY52241.1 - 0.00021 20.2 0.0 0.00023 20.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY52241.1 - 0.0082 15.5 0.1 0.01 15.2 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY52241.1 - 0.033 14.1 0.4 0.042 13.8 0.4 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family AMP-binding PF00501.28 KIY52242.1 - 1.3e-93 314.0 0.0 1.6e-93 313.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CoA_binding_2 PF13380.6 KIY52242.1 - 0.046 14.2 0.1 0.9 10.1 0.0 2.4 2 0 0 2 2 2 0 CoA binding domain DUF2104 PF09877.9 KIY52242.1 - 0.082 13.2 0.3 0.19 12.0 0.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) Retrotran_gag_2 PF14223.6 KIY52244.1 - 7.9e-06 25.6 0.2 0.00013 21.6 0.1 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type Alba PF01918.21 KIY52245.1 - 0.012 15.4 0.1 0.052 13.4 0.1 2.1 1 1 0 1 1 1 0 Alba La PF05383.17 KIY52246.1 - 2.4e-21 75.5 0.0 6.1e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KIY52246.1 - 7.4e-06 25.7 0.2 2.9e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KIY52246.1 - 0.12 13.0 14.1 0.4 11.3 12.6 2.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 API5 PF05918.11 KIY52246.1 - 0.24 10.2 4.0 0.36 9.6 4.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Helicase_C PF00271.31 KIY52247.1 - 1e-12 48.3 0.0 1.5e-11 44.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY52247.1 - 1.2e-08 35.0 0.0 3.8e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY52247.1 - 3.1e-05 24.1 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIY52247.1 - 0.0051 17.2 0.1 0.014 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain NST1 PF13945.6 KIY52249.1 - 1.2e-56 191.9 0.1 1.2e-56 191.9 0.1 3.8 2 1 1 3 3 3 1 Salt tolerance down-regulator CE2_N PF17996.1 KIY52250.1 - 0.0014 18.6 0.1 0.0027 17.7 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Sugar_tr PF00083.24 KIY52251.1 - 6.7e-91 305.4 13.9 7.7e-91 305.2 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY52251.1 - 8.4e-29 100.6 23.0 1.4e-18 66.9 4.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIY52251.1 - 0.00051 18.5 5.7 0.099 10.9 0.5 2.5 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3100 PF11299.8 KIY52251.1 - 0.056 12.8 2.4 0.091 12.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3100) Pkinase PF00069.25 KIY52252.1 - 2.6e-19 69.6 0.0 2.8e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52252.1 - 3.7e-06 26.4 0.0 3.9e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY52252.1 - 0.00015 21.2 0.0 0.00016 21.1 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY52252.1 - 0.0036 16.2 0.0 0.0038 16.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY52252.1 - 0.053 12.9 0.1 0.064 12.6 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY52252.1 - 0.062 13.2 0.2 0.078 12.9 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_10 PF05971.12 KIY52254.1 - 4.4e-71 239.7 0.0 5.1e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KIY52254.1 - 0.0015 18.1 0.0 0.0055 16.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain TrmK PF04816.12 KIY52254.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_18 PF12847.7 KIY52254.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cellulase PF00150.18 KIY52257.1 - 1.3e-10 41.2 6.9 2e-10 40.6 6.9 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sugar_tr PF00083.24 KIY52258.1 - 1.6e-08 33.9 13.0 4.6e-08 32.3 13.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY52258.1 - 0.0002 20.4 9.2 0.0002 20.4 9.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily COMMD1_N PF17221.3 KIY52260.1 - 0.024 14.9 0.1 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 COMMD1 N-terminal domain SgrT PF15894.5 KIY52261.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT PH PF00169.29 KIY52262.1 - 2.8e-10 40.6 0.0 6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KIY52262.1 - 0.011 16.1 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PX PF00787.24 KIY52262.1 - 0.038 14.0 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 PX domain Tfb4 PF03850.14 KIY52266.1 - 0.46 9.9 3.4 0.57 9.6 3.4 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF1424 PF07232.11 KIY52267.1 - 0.041 12.9 0.2 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Putative rep protein (DUF1424) Plavaka PF18759.1 KIY52268.1 - 2.9e-33 115.5 0.1 4.3e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase YmcE_antitoxin PF15939.5 KIY52268.1 - 0.0016 18.5 0.4 0.059 13.5 0.1 2.4 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system PI3K_1B_p101 PF10486.9 KIY52270.1 - 0.043 11.6 8.3 0.064 11.0 8.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ABA_GPCR PF12430.8 KIY52271.1 - 4.9e-42 143.7 20.7 4.9e-32 111.1 8.7 3.0 2 1 1 3 3 3 2 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KIY52271.1 - 5.2e-12 45.7 0.1 5.2e-12 45.7 0.1 2.1 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal SH PF01445.17 KIY52271.1 - 0.026 14.5 1.0 0.11 12.5 1.0 2.1 1 0 0 1 1 1 0 Viral small hydrophobic protein DUF2353 PF09789.9 KIY52271.1 - 0.11 11.9 1.0 0.15 11.4 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) HAUS-augmin3 PF14932.6 KIY52271.1 - 0.36 10.4 2.6 0.52 9.8 2.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Ni_hydr_CYTB PF01292.20 KIY52271.1 - 2.1 7.9 14.1 13 5.3 0.2 3.1 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 End3 PF12761.7 KIY52271.1 - 6.7 6.8 6.2 15 5.7 2.9 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 EF1G PF00647.19 KIY52272.1 - 2.1e-42 143.5 0.0 3.4e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 KIY52272.1 - 7.7e-11 42.2 0.0 2e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY52272.1 - 6.8e-08 32.6 0.5 2e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY52272.1 - 1.1e-06 28.7 0.0 3.8e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY52272.1 - 1.9e-06 27.8 0.0 5.3e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY52272.1 - 5.1e-05 23.6 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY52272.1 - 0.0013 19.0 0.0 0.0042 17.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain FGF-BP1 PF06473.12 KIY52272.1 - 0.13 12.0 1.1 0.19 11.6 1.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Tom37 PF10568.9 KIY52272.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_5 PF18485.1 KIY52272.1 - 0.19 12.1 0.0 0.54 10.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RNA_pol_Rpc4 PF05132.14 KIY52272.1 - 0.23 11.9 8.4 0.38 11.2 8.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 p450 PF00067.22 KIY52273.1 - 7.3e-69 232.7 0.0 1.5e-68 231.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M16 PF00675.20 KIY52275.1 - 5.8e-21 75.0 0.1 9.6e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIY52275.1 - 0.002 18.2 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Polysacc_lyase PF14099.6 KIY52276.1 - 0.00086 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase UPF0061 PF02696.14 KIY52277.1 - 5.1e-05 22.2 0.1 0.0007 18.5 0.1 2.0 1 1 1 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family Methyltransf_23 PF13489.6 KIY52279.1 - 4.1e-10 39.7 0.0 6.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY52279.1 - 9.2e-10 39.0 0.0 1.9e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY52279.1 - 8.1e-08 32.9 0.0 1.5e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY52279.1 - 1.7e-07 31.8 0.0 3.2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY52279.1 - 0.00024 20.9 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_2 PF02230.16 KIY52280.1 - 2e-55 188.0 0.0 4.1e-55 186.9 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KIY52280.1 - 2.8e-07 30.0 0.1 0.13 11.5 0.1 3.2 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY52280.1 - 1e-05 26.3 0.1 1.3e-05 26.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KIY52280.1 - 0.016 14.8 0.0 0.036 13.7 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KIY52280.1 - 0.03 14.2 0.1 0.11 12.4 0.0 1.7 1 1 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 KIY52280.1 - 0.041 13.5 0.0 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KIY52280.1 - 0.051 13.2 0.6 0.53 9.9 0.1 2.4 2 1 1 3 3 3 0 alpha/beta hydrolase fold Acetyltransf_3 PF13302.7 KIY52281.1 - 4e-19 69.7 0.0 1.7e-18 67.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY52281.1 - 4.3e-06 27.0 0.0 6.6e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KIY52281.1 - 0.00067 19.8 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIY52281.1 - 0.0017 18.0 0.1 0.038 13.7 0.0 2.3 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY52281.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RRM_1 PF00076.22 KIY52282.1 - 0.0071 16.2 0.3 1.7 8.6 0.1 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPS_reduct PF01507.19 KIY52283.1 - 3.8e-32 111.7 0.0 4.5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribonucleas_3_3 PF14622.6 KIY52284.1 - 1.4e-16 60.8 0.0 2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIY52284.1 - 3e-15 56.7 0.0 1.2e-14 54.8 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KIY52284.1 - 7.2e-09 36.2 0.0 1.4e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cyt-b5 PF00173.28 KIY52285.1 - 2.4e-19 69.2 0.1 3.7e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nup188 PF10487.9 KIY52286.1 - 5.1e-44 150.5 0.0 2.6e-43 148.1 0.0 2.1 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 KIY52286.1 - 6.2e-06 25.3 1.5 1.2e-05 24.3 1.5 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain DUF3361 PF11841.8 KIY52286.1 - 0.029 14.3 0.1 0.14 12.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) ATR13 PF16829.5 KIY52286.1 - 0.18 12.2 0.0 0.48 10.8 0.0 1.6 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector Scramblase PF03803.15 KIY52286.1 - 0.2 11.0 0.1 0.36 10.1 0.1 1.4 1 0 0 1 1 1 0 Scramblase CLPTM1 PF05602.12 KIY52287.1 - 1.8e-137 458.9 0.5 2.2e-137 458.6 0.5 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KIY52287.1 - 1.2e-05 25.0 0.6 0.0013 18.5 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat B-block_TFIIIC PF04182.12 KIY52288.1 - 0.0034 17.5 0.2 0.015 15.5 0.0 2.2 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC UBN_AB PF14075.6 KIY52288.1 - 0.087 12.5 3.7 2.8 7.6 0.1 2.8 2 0 0 2 2 2 0 Ubinuclein conserved middle domain RRM_1 PF00076.22 KIY52289.1 - 7.3e-23 80.2 0.1 1.7e-12 47.0 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIY52289.1 - 0.0017 18.3 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KIY52289.1 - 0.086 12.6 0.1 8.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DUF4808 PF16066.5 KIY52289.1 - 0.16 12.6 0.9 1.1 9.8 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4808) Ofd1_CTDD PF10637.9 KIY52290.1 - 5.5e-76 255.3 0.0 6.9e-74 248.4 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KIY52290.1 - 2.1e-27 95.6 0.0 6.1e-27 94.1 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KIY52290.1 - 2.5e-13 50.7 0.0 9.9e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PGF-CTERM PF18204.1 KIY52291.1 - 0.12 12.3 3.4 0.37 10.8 3.4 1.9 1 0 0 1 1 1 0 PGF-CTERM motif PGAP1 PF07819.13 KIY52292.1 - 1.3e-52 178.8 0.0 3.6e-52 177.4 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KIY52292.1 - 1.6e-05 25.6 6.4 1.6e-05 25.6 6.4 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY52292.1 - 0.0041 16.8 0.1 0.0092 15.7 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY52292.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KIY52292.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KIY52292.1 - 0.2 11.4 0.0 0.62 9.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family 14-3-3 PF00244.20 KIY52293.1 - 1.7e-107 358.0 3.4 1.9e-107 357.8 3.4 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 KIY52293.1 - 0.32 11.5 2.9 0.57 10.7 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AA_permease PF00324.21 KIY52295.1 - 5.9e-106 354.9 42.0 7.3e-106 354.6 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY52295.1 - 1.2e-28 100.2 46.2 1.8e-28 99.5 46.2 1.2 1 0 0 1 1 1 1 Amino acid permease DAO PF01266.24 KIY52296.1 - 1e-39 137.1 0.4 1.3e-39 136.8 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY52296.1 - 0.00052 19.2 0.4 0.68 8.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIY52296.1 - 0.00056 19.2 0.1 0.094 11.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY52296.1 - 0.00064 19.9 0.1 0.0015 18.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY52296.1 - 0.0017 17.7 0.0 0.0045 16.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KIY52296.1 - 0.0054 15.6 0.0 0.009 14.9 0.0 1.3 1 0 0 1 1 1 1 MCRA family Thi4 PF01946.17 KIY52296.1 - 0.039 13.2 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Defensin_big PF14862.6 KIY52296.1 - 0.086 13.2 1.4 0.19 12.1 1.4 1.5 1 0 0 1 1 1 0 Big defensin NAD_binding_9 PF13454.6 KIY52296.1 - 0.22 11.5 0.2 17 5.4 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding CorA PF01544.18 KIY52297.1 - 7.7e-44 150.2 0.5 1.1e-43 149.7 0.5 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KIY52297.1 - 0.037 14.1 1.1 0.062 13.3 0.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exo70 PF03081.15 KIY52298.1 - 1e-34 120.3 0.0 2e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Snapin_Pallidin PF14712.6 KIY52298.1 - 0.037 14.4 1.3 0.096 13.1 1.3 1.7 1 0 0 1 1 1 0 Snapin/Pallidin HSBP1 PF06825.12 KIY52298.1 - 0.18 11.7 1.3 0.49 10.3 0.6 2.2 1 1 0 1 1 1 0 Heat shock factor binding protein 1 MBOAT_2 PF13813.6 KIY52299.1 - 6.6e-25 87.2 1.9 2.4e-24 85.4 1.9 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PLU-1 PF08429.11 KIY52300.1 - 2.1e-46 158.7 3.4 4.1e-46 157.7 3.4 1.6 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 KIY52300.1 - 1.1e-38 132.1 0.1 3e-38 130.8 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KIY52300.1 - 1e-17 64.6 0.0 2.9e-17 63.1 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KIY52300.1 - 2.9e-14 52.7 45.7 7.1e-11 41.8 8.4 4.6 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.16 KIY52300.1 - 2.6e-13 50.1 7.4 2.6e-13 50.1 7.4 3.0 3 0 0 3 3 3 1 C5HC2 zinc finger JmjN PF02375.17 KIY52300.1 - 1.1e-12 47.7 0.7 2.6e-12 46.5 0.7 1.7 1 0 0 1 1 1 1 jmjN domain Prok-RING_1 PF14446.6 KIY52300.1 - 6.3 6.8 30.2 0.084 12.8 8.1 3.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Uds1 PF15456.6 KIY52302.1 - 1.2e-30 106.3 8.9 1.2e-30 106.3 8.9 5.7 4 2 2 6 6 6 1 Up-regulated During Septation DUF3786 PF12654.7 KIY52302.1 - 0.22 11.1 0.7 0.45 10.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) DUF4239 PF14023.6 KIY52302.1 - 0.66 9.7 4.8 2.8 7.6 4.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Pkinase PF00069.25 KIY52303.1 - 4.8e-56 190.1 0.0 5.6e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52303.1 - 3.4e-41 141.3 0.0 4.2e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY52303.1 - 2.1e-08 33.4 0.0 3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY52303.1 - 0.0075 15.6 0.0 0.016 14.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KIY52303.1 - 0.019 14.9 0.1 0.27 11.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family VIR_N PF15912.5 KIY52304.1 - 0.073 12.7 0.1 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 Virilizer, N-terminal Ribosomal_L34 PF00468.17 KIY52305.1 - 1.3e-20 73.0 7.7 1.7e-20 72.7 7.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 F-box PF00646.33 KIY52307.1 - 0.0057 16.5 1.9 0.015 15.2 1.9 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY52307.1 - 0.017 15.0 1.9 0.046 13.6 1.1 2.2 2 1 0 2 2 2 0 F-box 1-cysPrx_C PF10417.9 KIY52307.1 - 0.13 12.2 0.2 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin F-box-like PF12937.7 KIY52307.1 - 0.15 12.0 1.9 0.4 10.6 1.9 1.7 1 0 0 1 1 1 0 F-box-like ORMDL PF04061.14 KIY52308.1 - 7.6e-54 181.2 6.2 9.7e-54 180.9 6.2 1.1 1 0 0 1 1 1 1 ORMDL family THF_DHG_CYH PF00763.23 KIY52309.1 - 2.2e-26 92.4 0.0 3.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KIY52309.1 - 2.2e-15 56.3 0.4 2.5e-08 33.4 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OCD_Mu_crystall PF02423.15 KIY52309.1 - 0.054 12.4 0.1 0.079 11.9 0.1 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF3464 PF11947.8 KIY52310.1 - 0.057 13.2 0.1 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Cwf_Cwc_15 PF04889.12 KIY52310.1 - 0.52 10.0 9.7 0.86 9.3 9.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KIY52310.1 - 0.59 9.4 8.5 0.7 9.2 8.5 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 KIY52310.1 - 2.7 6.4 6.3 3.6 6.0 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 KIY52310.1 - 4.2 5.5 10.3 5.2 5.2 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family IPP-2 PF04979.14 KIY52311.1 - 6.5e-17 62.5 3.9 1.7e-16 61.2 3.9 1.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) STIMATE PF12400.8 KIY52312.1 - 6.1e-37 127.0 8.1 1.1e-36 126.1 8.1 1.4 1 0 0 1 1 1 1 STIMATE family AAA PF00004.29 KIY52313.1 - 2.1e-56 189.9 0.0 2.2e-39 134.9 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIY52313.1 - 3e-11 43.7 0.5 5.1e-05 23.6 0.1 4.2 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.6 KIY52313.1 - 1.6e-10 41.7 0.1 0.00026 21.4 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 KIY52313.1 - 8.9e-10 38.3 0.1 0.00024 20.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 KIY52313.1 - 1.7e-09 37.7 0.1 0.00022 21.0 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIY52313.1 - 3.6e-09 36.9 0.0 0.0006 20.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KIY52313.1 - 7.7e-09 35.2 0.1 1.8e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIY52313.1 - 2.4e-08 34.3 0.2 5.1e-05 23.5 0.1 3.2 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KIY52313.1 - 3.8e-08 33.4 0.0 0.0029 17.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KIY52313.1 - 2.6e-07 31.3 0.0 0.025 15.1 0.0 3.1 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KIY52313.1 - 1e-06 28.3 0.2 0.0094 15.4 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KIY52313.1 - 1.7e-06 27.9 0.0 0.026 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KIY52313.1 - 2.4e-06 27.2 1.0 5.1e-05 23.0 0.2 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.22 KIY52313.1 - 2.6e-06 27.8 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KIY52313.1 - 3.9e-06 26.9 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KIY52313.1 - 5.5e-06 26.4 0.2 0.017 15.0 0.0 3.0 3 0 0 3 3 3 2 NACHT domain Sigma54_activat PF00158.26 KIY52313.1 - 6.8e-06 25.9 0.0 0.055 13.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KIY52313.1 - 7.6e-06 25.8 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 KIY52313.1 - 1.3e-05 25.7 0.1 0.045 14.3 0.1 2.6 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 KIY52313.1 - 1.5e-05 25.0 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KIY52313.1 - 2.6e-05 24.1 0.1 0.089 12.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KIY52313.1 - 3e-05 23.4 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 KIY52313.1 - 4.7e-05 23.0 0.0 0.052 13.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 KIY52313.1 - 7.7e-05 22.6 0.0 0.072 13.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KIY52313.1 - 0.00014 21.2 0.1 0.14 11.4 0.1 2.4 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KIY52313.1 - 0.00015 21.2 0.4 0.028 13.8 0.1 3.0 2 1 1 3 3 3 1 KaiC AAA_30 PF13604.6 KIY52313.1 - 0.0002 21.1 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KIY52313.1 - 0.00026 21.0 0.0 0.053 13.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KIY52313.1 - 0.00076 19.8 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 KIY52313.1 - 0.00081 19.8 0.0 0.086 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY52313.1 - 0.0011 18.5 3.3 1.1 8.8 0.1 3.9 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.6 KIY52313.1 - 0.0013 19.1 0.0 0.75 10.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KIY52313.1 - 0.0013 18.1 0.1 0.16 11.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Hydin_ADK PF17213.3 KIY52313.1 - 0.0014 19.0 0.1 0.43 10.8 0.0 2.3 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain PhoH PF02562.16 KIY52313.1 - 0.0023 17.4 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein CPT PF07931.12 KIY52313.1 - 0.0024 17.7 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 KIY52313.1 - 0.003 17.0 0.0 0.76 9.1 0.1 3.1 2 1 0 2 2 2 1 Bacterial TniB protein ATPase_2 PF01637.18 KIY52313.1 - 0.0039 17.2 0.3 3.5 7.5 0.0 3.3 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIY52313.1 - 0.005 16.0 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Torsin PF06309.11 KIY52313.1 - 0.0066 16.5 0.0 4.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Torsin T2SSE PF00437.20 KIY52313.1 - 0.007 15.5 0.0 3.4 6.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KIY52313.1 - 0.0076 16.0 0.0 1.2 8.8 0.0 2.5 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 KIY52313.1 - 0.012 15.0 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 KIY52313.1 - 0.014 15.2 0.1 8 6.1 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase NTPase_1 PF03266.15 KIY52313.1 - 0.031 14.2 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 KIY52313.1 - 0.11 12.2 0.1 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain HBM PF16591.5 KIY52313.1 - 0.11 11.8 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Helical bimodular sensor domain cobW PF02492.19 KIY52313.1 - 0.12 12.0 0.0 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activ_2 PF14532.6 KIY52313.1 - 0.13 12.4 0.0 29 4.8 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain IPT PF01745.16 KIY52313.1 - 0.16 11.3 0.0 0.66 9.3 0.0 1.9 2 0 0 2 2 2 0 Isopentenyl transferase Rad17 PF03215.15 KIY52313.1 - 0.16 11.9 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Zot PF05707.12 KIY52313.1 - 0.18 11.4 0.0 20 4.8 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DUF1748 PF08520.10 KIY52315.1 - 4.1e-19 68.3 0.0 4.6e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DUF2009 PF09418.10 KIY52316.1 - 1.8e-212 706.4 0.0 2.1e-212 706.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 KIY52316.1 - 3.3e-06 27.2 3.7 6.2e-06 26.3 3.7 1.5 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 KIY52316.1 - 0.0013 18.9 3.5 0.0031 17.7 3.5 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain GRDB PF07355.12 KIY52316.1 - 0.023 14.0 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) zf-C3HC4_3 PF13920.6 KIY52316.1 - 0.085 12.7 4.5 0.19 11.6 4.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 KIY52316.1 - 1.6 9.0 5.2 0.96 9.7 2.7 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain CIA30 PF08547.12 KIY52317.1 - 3.8e-25 88.8 0.0 5.3e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) eIF3m_C_helix PF18005.1 KIY52318.1 - 8e-14 51.0 3.0 3e-13 49.2 3.0 2.1 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 KIY52318.1 - 1.4e-13 51.2 0.1 3.8e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 PCI domain Phage_terminase PF10668.9 KIY52318.1 - 0.034 14.2 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Phage terminase small subunit UCR_14kD PF02271.16 KIY52318.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Pro-kuma_activ PF09286.11 KIY52319.1 - 2.5e-35 121.8 0.1 5.9e-35 120.6 0.1 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIY52319.1 - 4.5e-10 39.3 0.4 4.6e-08 32.7 0.0 2.2 1 1 1 2 2 2 2 Subtilase family Pro-kuma_activ PF09286.11 KIY52320.1 - 3.2e-38 131.2 0.6 4.8e-38 130.7 0.6 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIY52320.1 - 0.00079 18.8 0.0 0.0031 16.8 0.0 2.1 1 1 0 1 1 1 1 Subtilase family Hep_59 PF07052.11 KIY52321.1 - 3.6e-29 101.6 1.7 3.6e-29 101.6 1.7 1.9 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Nuclease_act PF08133.11 KIY52321.1 - 0.013 15.6 0.7 0.78 10.0 0.1 2.5 2 0 0 2 2 2 0 Anticodon nuclease activator family Activator-TraM PF11657.8 KIY52321.1 - 0.078 12.8 0.1 0.92 9.3 0.0 2.2 2 0 0 2 2 2 0 Transcriptional activator TraM TIP41 PF04176.13 KIY52322.1 - 2.3e-60 203.0 0.0 2.7e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 TIP41-like family DLIC PF05783.11 KIY52323.1 - 4.5e-43 147.8 0.3 6.6e-33 114.3 0.0 3.9 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) Roc PF08477.13 KIY52323.1 - 0.002 18.3 0.0 0.017 15.3 0.0 2.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIY52323.1 - 0.0027 18.1 0.0 0.0074 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KIY52323.1 - 0.01 15.4 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KIY52323.1 - 0.041 13.9 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY52323.1 - 0.1 11.9 0.1 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KIY52323.1 - 0.13 12.1 0.0 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KIY52323.1 - 0.17 12.2 0.0 0.55 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain TFIIB PF00382.19 KIY52326.1 - 2.7e-35 120.2 0.1 1.6e-20 72.9 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KIY52326.1 - 3.7e-13 48.8 1.3 6.2e-13 48.0 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KIY52326.1 - 0.0031 17.3 0.2 0.0051 16.6 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RB_B PF01857.20 KIY52326.1 - 0.018 15.1 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_5 PF01022.20 KIY52326.1 - 0.078 12.9 0.1 21 5.1 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Cyclin_C PF02984.19 KIY52326.1 - 0.16 12.1 0.0 1 9.5 0.0 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain APH PF01636.23 KIY52327.1 - 2.1e-06 27.8 0.0 2.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Phage_integrase PF00589.22 KIY52329.1 - 0.00025 20.9 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF3301 PF11743.8 KIY52329.1 - 0.08 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) DUF3684 PF12449.8 KIY52329.1 - 0.29 8.9 0.0 0.37 8.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) RRS1 PF04939.12 KIY52330.1 - 7.7e-59 198.2 3.4 1.2e-58 197.5 3.4 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Oxidored_FMN PF00724.20 KIY52331.1 - 2.1e-63 214.7 0.0 2.9e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KIY52331.1 - 0.00035 19.8 0.0 0.00058 19.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TFIID_20kDa PF03847.13 KIY52332.1 - 2.5e-26 91.9 0.2 3.6e-26 91.5 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KIY52332.1 - 0.00034 20.8 0.0 0.00059 20.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KIY52332.1 - 0.0025 17.9 0.0 0.0043 17.1 0.0 1.4 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ribonuc_red_sm PF00268.21 KIY52335.1 - 2.6e-73 246.9 2.6 3.1e-65 220.4 0.7 3.0 1 1 1 2 2 2 2 Ribonucleotide reductase, small chain DUF4801 PF16059.5 KIY52335.1 - 0.035 14.1 0.3 0.059 13.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) MFS_1 PF07690.16 KIY52336.1 - 9e-31 107.1 35.3 9e-31 107.1 35.3 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY52336.1 - 2e-11 43.4 0.5 2e-11 43.4 0.5 3.4 2 2 0 3 3 3 1 Sugar (and other) transporter UPF0227 PF05728.12 KIY52336.1 - 0.099 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Na_H_antiport_2 PF13726.6 KIY52336.1 - 8.2 6.6 7.3 0.77 9.9 1.5 2.3 3 0 0 3 3 3 0 Na+-H+ antiporter family DEAD PF00270.29 KIY52337.1 - 5.9e-52 176.0 0.0 4e-51 173.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY52337.1 - 3.2e-26 91.9 0.0 1.5e-25 89.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY52337.1 - 0.0022 18.0 0.0 0.0061 16.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIY52337.1 - 0.079 12.3 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Nsp1_C PF05064.13 KIY52338.1 - 1.4e-30 105.5 0.7 6.9e-30 103.2 0.1 2.0 2 0 0 2 2 2 1 Nsp1-like C-terminal region BLOC1_2 PF10046.9 KIY52338.1 - 0.013 15.8 5.5 0.74 10.2 0.2 2.9 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 KIY52338.1 - 0.018 15.1 6.2 0.045 13.8 0.2 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KIY52338.1 - 0.081 13.0 4.1 3.4 7.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 KIY52338.1 - 0.084 12.7 2.4 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Allexi_40kDa PF05549.11 KIY52338.1 - 0.11 12.0 1.8 2.9 7.3 0.1 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein ING PF12998.7 KIY52338.1 - 0.11 13.1 1.5 1.9 9.1 0.3 2.4 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Syntaxin-6_N PF09177.11 KIY52338.1 - 0.24 12.0 4.1 1.1 9.8 0.6 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal EzrA PF06160.12 KIY52338.1 - 0.37 8.9 4.1 0.81 7.8 3.1 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA CENP-Q PF13094.6 KIY52338.1 - 0.63 10.2 6.7 4.5 7.5 6.5 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Snapin_Pallidin PF14712.6 KIY52338.1 - 0.72 10.3 4.6 4.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Spc24 PF08286.11 KIY52338.1 - 1.2 9.4 5.6 9.8 6.5 0.9 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Laminin_II PF06009.12 KIY52338.1 - 2.6 8.0 6.4 13 5.8 0.2 2.8 2 2 1 3 3 3 0 Laminin Domain II Uricase PF01014.18 KIY52339.1 - 2.5e-61 205.7 0.6 2.4e-29 102.2 0.0 2.0 2 0 0 2 2 2 2 Uricase Acetyltransf_16 PF05301.11 KIY52339.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 FYVE PF01363.21 KIY52340.1 - 4.4e-16 58.8 9.4 4.4e-16 58.8 9.4 2.6 3 0 0 3 3 3 1 FYVE zinc finger Prok-RING_4 PF14447.6 KIY52340.1 - 0.085 12.7 10.6 5.3 7.0 0.0 3.8 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 TackOD1 PF18551.1 KIY52340.1 - 3 7.5 11.7 5.5 6.6 3.6 2.9 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 Pyocin_S PF06958.12 KIY52341.1 - 0.04 14.5 0.5 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 S-type Pyocin LCM PF04072.14 KIY52342.1 - 1.9e-21 76.9 0.0 3.6e-21 76.0 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Kri1 PF05178.12 KIY52343.1 - 3.8e-26 91.6 11.0 3.8e-26 91.6 11.0 6.4 6 1 1 7 7 7 1 KRI1-like family Kri1_C PF12936.7 KIY52343.1 - 9e-25 86.7 0.3 9e-25 86.7 0.3 6.4 7 1 0 7 7 7 1 KRI1-like family C-terminal DUF5601 PF18151.1 KIY52343.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) UPRTase PF14681.6 KIY52344.1 - 1.6e-64 217.2 0.0 1.9e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KIY52344.1 - 0.048 13.2 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain HMG_box_2 PF09011.10 KIY52345.1 - 0.027 15.1 3.1 0.077 13.6 0.2 2.9 3 0 0 3 3 3 0 HMG-box domain DUF3211 PF11485.8 KIY52345.1 - 0.12 12.5 0.1 0.3 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3211) Med4 PF10018.9 KIY52346.1 - 0.034 13.8 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Herpes_BLRF2 PF05812.12 KIY52346.1 - 0.13 12.4 0.3 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Cnn_1N PF07989.11 KIY52346.1 - 0.23 11.6 3.3 0.76 10.0 0.1 2.6 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Spc24 PF08286.11 KIY52346.1 - 0.61 10.3 2.4 2.3 8.5 0.1 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 UQ_con PF00179.26 KIY52348.1 - 4.3e-11 42.6 0.1 4.7e-11 42.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAM76 PF16046.5 KIY52349.1 - 0.018 14.4 0.4 0.018 14.4 0.4 1.5 2 0 0 2 2 2 0 FAM76 protein DUF2040 PF09745.9 KIY52349.1 - 4.9 7.2 11.0 0.37 10.9 4.5 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) KDZ PF18758.1 KIY52350.1 - 4.3e-22 78.8 0.0 6.5e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY52350.1 - 0.042 14.0 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases DHR10 PF18595.1 KIY52350.1 - 0.18 11.9 0.4 0.33 11.0 0.4 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain KDZ PF18758.1 KIY52351.1 - 8.6e-40 136.7 0.1 1.3e-39 136.1 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase HHH_8 PF14716.6 KIY52351.1 - 0.015 15.7 0.2 8.5 6.8 0.0 3.3 3 1 0 3 3 3 0 Helix-hairpin-helix domain Peptidase_S28 PF05577.12 KIY52352.1 - 2.8e-51 174.7 0.6 3.5e-51 174.4 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIY52352.1 - 0.0044 16.5 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family FAD_binding_1 PF00667.20 KIY52353.1 - 4.9e-53 180.0 0.0 8e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KIY52353.1 - 2.9e-07 31.1 0.0 7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KIY52353.1 - 0.0013 18.8 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF1966 PF09260.11 KIY52353.1 - 0.045 14.0 0.0 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) FAD_binding_6 PF00970.24 KIY52353.1 - 0.12 12.7 0.0 0.42 11.0 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Methyltransf_8 PF05148.15 KIY52354.1 - 5e-68 229.2 0.0 1.9e-67 227.3 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KIY52354.1 - 3e-07 31.0 0.0 9.4e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY52354.1 - 2.6e-06 28.1 0.0 9.9e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY52354.1 - 0.00024 20.9 0.0 0.54 10.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_29 PF03141.16 KIY52354.1 - 0.0016 17.1 0.0 0.33 9.5 0.0 2.1 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KIY52354.1 - 0.0095 16.7 0.0 0.037 14.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY52354.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KIY52354.1 - 0.031 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIY52354.1 - 0.068 12.7 0.0 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Zot PF05707.12 KIY52355.1 - 9.2e-05 22.2 0.0 0.00021 21.0 0.0 1.5 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF853 PF05872.12 KIY52355.1 - 0.0055 15.4 0.0 0.016 13.8 0.1 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 KIY52355.1 - 0.0059 16.9 0.1 2 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KIY52355.1 - 0.0061 17.0 0.1 0.37 11.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KIY52355.1 - 0.031 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KIY52355.1 - 0.047 14.1 0.2 7.2 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KIY52355.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DUF2075 PF09848.9 KIY52355.1 - 0.28 10.4 0.0 1.7 7.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF952 PF06108.12 KIY52356.1 - 4.5e-22 77.8 0.0 6.4e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) RIFIN PF02009.16 KIY52357.1 - 0.00048 20.1 10.0 0.0012 18.9 10.2 1.5 1 1 0 1 1 1 1 Rifin Adeno_E3_CR2 PF02439.15 KIY52357.1 - 0.12 12.1 1.6 0.26 11.1 1.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Baculo_11_kDa PF06143.11 KIY52357.1 - 1.7 8.3 4.1 1.4 8.5 0.6 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Orf78 PF06024.12 KIY52357.1 - 2.7 8.3 3.5 19 5.7 3.5 2.5 1 1 0 1 1 1 0 Orf78 (ac78) DUF2759 PF10958.8 KIY52360.1 - 0.1 12.4 1.2 0.85 9.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) Peptidase_C48 PF02902.19 KIY52363.1 - 8.7e-17 61.7 0.1 1.4e-16 61.0 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1069 PF06370.11 KIY52363.1 - 0.016 14.8 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Alpha-amylase_C PF02806.18 KIY52365.1 - 6.4e-06 26.5 0.0 1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Peptidase_M24 PF00557.24 KIY52366.1 - 3.7e-10 39.9 0.2 8.7e-10 38.6 0.1 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 Tetraspanin PF00335.20 KIY52367.1 - 2.3e-05 24.2 2.8 7.3e-05 22.6 3.4 1.6 1 1 1 2 2 2 1 Tetraspanin family DUF2070 PF09843.9 KIY52367.1 - 0.28 9.4 1.3 0.31 9.3 1.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4064 PF13273.6 KIY52367.1 - 2 8.8 5.2 4 7.8 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) ADH_zinc_N PF00107.26 KIY52368.1 - 1.4e-10 41.2 1.4 2.3e-10 40.6 1.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY52368.1 - 1.8e-09 37.4 0.6 6.8e-09 35.6 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIY52368.1 - 0.0089 15.9 0.1 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase adh_short PF00106.25 KIY52368.1 - 0.098 12.1 0.6 0.16 11.4 0.6 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KIY52368.1 - 0.13 13.3 0.6 0.36 11.9 0.6 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_hydro_16 PF00722.21 KIY52369.1 - 0.015 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 AAA-ATPase_like PF09820.9 KIY52370.1 - 7.4e-12 45.3 0.0 4.3e-11 42.8 0.0 2.0 1 1 1 2 2 2 1 Predicted AAA-ATPase zf-RVT PF13966.6 KIY52372.1 - 8.2e-08 32.9 1.4 1.5e-07 32.0 0.4 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase FAM72 PF14976.6 KIY52376.1 - 0.01 16.0 1.0 0.019 15.1 1.0 1.3 1 0 0 1 1 1 0 FAM72 protein ADH_zinc_N PF00107.26 KIY52377.1 - 1e-21 77.3 0.0 1.6e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY52377.1 - 8.4e-16 59.2 0.0 2.1e-15 58.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY52377.1 - 2.6e-07 30.5 0.0 1.7e-05 24.6 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain DUF2196 PF09962.9 KIY52378.1 - 0.017 15.1 0.6 0.031 14.3 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) ATP-synt_C PF00137.21 KIY52379.1 - 6.6e-33 112.9 36.8 9.2e-22 77.2 14.9 2.6 3 0 0 3 3 3 2 ATP synthase subunit C PIRT PF15099.6 KIY52379.1 - 0.69 9.5 7.7 0.23 11.0 0.5 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family AAA-ATPase_like PF09820.9 KIY52381.1 - 1.4e-17 64.1 0.0 1.9e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase Glyco_transf_7C PF02709.14 KIY52381.1 - 0.11 12.2 0.1 0.79 9.4 0.1 2.3 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase DNA_pol_phi PF04931.13 KIY52381.1 - 6 4.8 6.7 9.6 4.2 6.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4023 PF13215.6 KIY52382.1 - 1.6 8.8 4.4 0.94 9.5 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Glyco_hydro_45 PF02015.16 KIY52383.1 - 1.3e-12 48.1 0.1 1.4e-12 48.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 MFS_1 PF07690.16 KIY52384.1 - 1.3e-19 70.4 44.9 4.5e-12 45.6 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY52384.1 - 4.1e-17 62.2 19.9 3.4e-16 59.2 19.9 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter AAA-ATPase_like PF09820.9 KIY52385.1 - 4.7e-14 52.5 0.0 7.3e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase Phosphoprotein PF00922.17 KIY52385.1 - 0.062 12.9 1.2 0.1 12.2 1.2 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein AAA-ATPase_like PF09820.9 KIY52388.1 - 1.2e-16 61.0 0.0 1.8e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase RXT2_N PF08595.11 KIY52388.1 - 0.16 12.0 0.6 0.27 11.3 0.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 KIY52388.1 - 4.9 5.1 6.0 7 4.6 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 KIY52389.1 - 1.9e-59 201.2 0.0 2.1e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52389.1 - 8.5e-30 103.9 0.0 1.1e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY52389.1 - 2.4e-07 30.4 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY52389.1 - 8.2e-07 28.6 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY52389.1 - 9.3e-06 25.4 0.1 1.4e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY52389.1 - 1.7e-05 24.9 0.3 3.8e-05 23.7 0.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY52389.1 - 0.00011 21.3 0.1 0.00014 20.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-PolyVal PF18762.1 KIY52389.1 - 0.0033 17.4 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Choline_kinase PF01633.20 KIY52389.1 - 0.015 14.9 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 KIY52389.1 - 0.026 13.6 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KIY52389.1 - 0.064 12.0 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KIY52389.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 adh_short_C2 PF13561.6 KIY52390.1 - 1.9e-30 106.2 0.0 1.8e-28 99.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY52390.1 - 2e-29 102.5 0.0 6.3e-29 100.8 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIY52390.1 - 3.2e-07 30.4 0.1 7e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 KIY52390.1 - 0.055 12.7 0.1 0.11 11.8 0.1 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.10 KIY52390.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pyr_redox PF00070.27 KIY52390.1 - 0.1 13.2 0.5 0.19 12.3 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIY52390.1 - 0.16 11.6 0.2 0.25 11.0 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 KIY52391.1 - 1.4e-20 73.6 44.5 9.5e-13 47.8 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY52391.1 - 1.4e-16 60.4 19.6 2.6e-15 56.3 19.6 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter AAA-ATPase_like PF09820.9 KIY52392.1 - 1.8e-09 37.5 0.0 3.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Predicted AAA-ATPase DUF3750 PF12570.8 KIY52392.1 - 0.089 13.5 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3750) MFS_1 PF07690.16 KIY52394.1 - 6e-10 38.6 18.5 4.9e-09 35.6 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY52394.1 - 0.00067 18.6 7.3 0.0069 15.3 1.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter NDUF_C2 PF06374.11 KIY52394.1 - 0.19 11.9 0.3 7 6.8 0.0 2.8 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Aldo_ket_red PF00248.21 KIY52397.1 - 8.2e-59 199.2 0.0 9.8e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.28 KIY52398.1 - 6.3e-96 322.3 0.0 9.4e-95 318.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY52398.1 - 9.3e-05 22.4 0.0 0.00065 19.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY52398.1 - 0.00021 20.8 0.7 0.0013 18.2 0.7 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family PcfK PF14058.6 KIY52398.1 - 0.018 15.3 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 PcfK-like protein Pkinase PF00069.25 KIY52399.1 - 4e-69 232.9 0.0 4.5e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52399.1 - 2.4e-40 138.5 0.0 2.9e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY52399.1 - 1.8e-05 24.2 0.0 4.2e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KIY52399.1 - 0.0059 16.0 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY52399.1 - 0.02 14.5 0.2 0.2 11.3 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIY52399.1 - 0.029 14.3 0.1 2.8 7.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Radical_SAM_C PF16199.5 KIY52399.1 - 0.12 12.4 0.2 0.39 10.8 0.0 2.0 2 1 0 2 2 2 0 Radical_SAM C-terminal domain MBOAT_2 PF13813.6 KIY52401.1 - 7.2e-15 55.0 6.3 7.2e-15 55.0 6.3 2.5 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Pectinesterase PF01095.19 KIY52402.1 - 9.3e-37 126.3 1.4 2.9e-31 108.3 0.4 2.1 2 0 0 2 2 2 2 Pectinesterase AAA-ATPase_like PF09820.9 KIY52403.1 - 2.9e-15 56.5 0.0 4.4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase Peptidase_M64 PF09471.10 KIY52404.1 - 1.3e-28 100.3 0.0 1.3e-27 97.0 0.0 2.0 1 1 0 1 1 1 1 IgA Peptidase M64 GMC_oxred_N PF00732.19 KIY52405.1 - 9.7e-48 163.0 0.0 1.8e-47 162.2 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY52405.1 - 3e-27 95.9 0.0 4.8e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIY52405.1 - 7.9e-05 21.9 1.8 0.0019 17.3 0.2 2.8 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KIY52405.1 - 0.00025 21.2 0.2 0.00075 19.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY52405.1 - 0.00087 19.0 0.5 0.0035 17.0 0.4 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIY52405.1 - 0.0049 17.4 0.1 0.066 13.8 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY52405.1 - 0.009 15.3 0.2 0.016 14.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY52405.1 - 0.015 14.6 0.1 0.036 13.3 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY52405.1 - 0.033 13.3 0.1 0.059 12.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIY52405.1 - 0.039 13.2 0.2 0.42 9.8 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIY52405.1 - 0.044 13.1 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KIY52405.1 - 0.097 11.4 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KIY52405.1 - 0.13 12.5 0.1 0.33 11.2 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 KIY52408.1 - 2.6e-65 220.4 0.0 2.9e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52408.1 - 1.1e-36 126.5 0.0 1.3e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY52408.1 - 6.9e-06 25.6 0.0 1.6e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY52408.1 - 0.012 15.6 2.8 0.56 10.1 1.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KIY52408.1 - 0.022 14.4 0.1 0.5 10.0 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY52408.1 - 0.092 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KIY52408.1 - 0.26 10.3 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CTU2 PF10288.9 KIY52409.1 - 5.5e-18 65.3 1.7 9.2e-18 64.5 0.2 2.2 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 Cytochrome_C554 PF13435.6 KIY52409.1 - 0.049 14.5 2.3 0.071 14.0 0.2 2.3 2 0 0 2 2 2 0 Cytochrome c554 and c-prime PAPS_reduct PF01507.19 KIY52409.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Gin PF10764.9 KIY52409.1 - 0.38 10.8 4.8 1 9.3 0.3 2.9 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin zf-C3HC4_3 PF13920.6 KIY52409.1 - 0.7 9.8 14.5 1.1 9.1 4.1 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KIY52409.1 - 7.3 6.7 14.7 3.7 7.7 2.7 3.7 2 2 1 3 3 3 0 Double zinc ribbon F-box-like PF12937.7 KIY52410.1 - 3.4e-06 26.8 0.6 1.1e-05 25.2 0.6 1.9 1 0 0 1 1 1 1 F-box-like Syntaxin_2 PF14523.6 KIY52411.1 - 4.1e-21 75.2 7.2 3.4e-20 72.3 4.8 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KIY52411.1 - 5.1e-14 52.0 2.3 3.4e-13 49.4 0.2 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KIY52411.1 - 2.9e-06 27.1 15.2 1e-05 25.3 15.2 1.8 1 1 0 1 1 1 1 Syntaxin Prominin PF05478.11 KIY52411.1 - 0.016 13.2 6.9 0.02 12.9 6.9 1.1 1 0 0 1 1 1 0 Prominin FlaC_arch PF05377.11 KIY52411.1 - 1.4 9.3 4.6 62 4.1 0.0 4.1 2 2 2 5 5 5 0 Flagella accessory protein C (FlaC) ALMT PF11744.8 KIY52411.1 - 2.4 6.9 9.8 3.1 6.5 9.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF16 PF01519.16 KIY52411.1 - 8.3 7.0 10.3 1.1e+02 3.3 8.6 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2367 PF10164.9 KIY52412.1 - 3.5e-09 37.1 2.8 5.4e-09 36.5 2.7 1.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) ATP1G1_PLM_MAT8 PF02038.16 KIY52412.1 - 0.24 10.9 1.8 0.35 10.3 1.8 1.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Cellulose_synt PF03552.14 KIY52413.1 - 0.067 11.7 0.0 0.073 11.5 0.0 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF639 PF04842.12 KIY52413.1 - 0.21 11.0 0.1 0.24 10.8 0.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Ribosomal_L5_C PF00673.21 KIY52414.1 - 1.1e-23 83.2 0.0 1.7e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KIY52414.1 - 0.00027 21.2 0.0 0.00066 20.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 DUF4381 PF14316.6 KIY52415.1 - 0.0076 16.5 0.4 0.011 16.0 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF4381 PF14316.6 KIY52418.1 - 0.0051 17.1 1.0 0.056 13.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) DUF2975 PF11188.8 KIY52418.1 - 0.0089 15.9 0.8 0.58 10.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2975) Orf78 PF06024.12 KIY52418.1 - 0.012 15.9 3.8 1.2 9.5 0.5 2.3 2 0 0 2 2 2 0 Orf78 (ac78) OAD_gamma PF04277.13 KIY52418.1 - 0.55 10.9 1.7 0.68 10.6 0.0 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF2244 PF10003.9 KIY52418.1 - 0.95 9.1 3.9 9.4 5.9 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF2556 PF10831.8 KIY52418.1 - 5.8 6.9 8.6 18 5.4 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2556) NOT2_3_5 PF04153.18 KIY52419.1 - 2.4e-30 105.3 0.3 4.6e-30 104.4 0.3 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family HD PF01966.22 KIY52421.1 - 3.7e-12 46.5 0.0 1.4e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 HD domain Glyco_hydro_20 PF00728.22 KIY52422.1 - 1e-81 275.1 0.0 1.6e-81 274.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KIY52422.1 - 6.7e-16 59.2 0.0 1.3e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KIY52422.1 - 6.3e-07 30.2 0.1 1.5e-06 29.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 KIY52423.1 - 3e-50 171.3 0.0 4e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.22 KIY52424.1 - 4.3e-76 256.6 0.1 1.1e-74 252.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KIY52424.1 - 3.3e-16 60.2 0.0 7.1e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KIY52424.1 - 1.4e-07 32.3 0.0 2.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 KIY52425.1 - 1.2e-70 238.7 0.0 2.4e-70 237.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KIY52425.1 - 3.3e-10 40.8 0.0 2.5e-09 37.9 0.0 2.3 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KIY52425.1 - 0.00029 21.6 0.0 0.0014 19.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 WD40 PF00400.32 KIY52426.1 - 0.0012 19.6 5.3 0.55 11.2 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Glyoxal_oxid_N PF07250.11 KIY52426.1 - 0.0049 16.1 0.3 1.3 8.1 0.3 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus CbiN PF02553.15 KIY52426.1 - 0.048 13.6 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Cobalt transport protein component CbiN RNA_pol_Rpb4 PF03874.16 KIY52427.1 - 1.6e-22 80.2 0.3 2e-22 79.8 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DED PF01335.21 KIY52427.1 - 0.047 14.0 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Death effector domain Phage_Cox PF10743.9 KIY52427.1 - 0.075 13.1 0.1 1 9.5 0.0 2.4 1 1 1 2 2 2 0 Regulatory phage protein cox RNA_pol_Rpb5_C PF01191.19 KIY52427.1 - 0.14 12.0 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Prenyltrans PF00432.21 KIY52428.1 - 2.7e-36 123.0 7.3 3.7e-09 36.2 1.2 5.4 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KIY52428.1 - 0.012 14.7 0.0 1.4 8.0 0.0 2.8 1 1 2 3 3 3 0 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KIY52428.1 - 0.13 11.4 0.0 5.8 5.9 0.0 2.5 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 KIY52428.1 - 0.21 10.6 0.0 7.9 5.4 0.0 2.5 2 1 0 2 2 2 0 A-macroglobulin TED domain Pkinase PF00069.25 KIY52431.1 - 7.4e-75 251.7 0.0 1.5e-74 250.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52431.1 - 1.8e-52 178.2 0.0 5.9e-52 176.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RICTOR_N PF14664.6 KIY52431.1 - 0.0031 16.6 4.0 0.61 9.0 0.2 2.4 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term Pkinase_fungal PF17667.1 KIY52431.1 - 0.0035 16.2 0.0 0.015 14.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KIY52431.1 - 0.0043 16.4 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Ric8 PF10165.9 KIY52431.1 - 0.014 14.4 0.0 3.5 6.6 0.1 2.5 2 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Cupin_2 PF07883.11 KIY52432.1 - 1.1e-10 41.1 0.1 2.6e-10 39.9 0.1 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KIY52432.1 - 0.0027 17.4 0.0 0.0082 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KIY52432.1 - 0.004 16.8 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Activator_LAG-3 PF11498.8 KIY52432.1 - 0.081 11.9 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SH3_6 PF12913.7 KIY52432.1 - 0.14 11.8 0.2 0.29 10.7 0.1 1.6 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) TF_Zn_Ribbon PF08271.12 KIY52434.1 - 0.15 11.6 0.0 0.45 10.1 0.0 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding SusE PF14292.6 KIY52435.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 SusE outer membrane protein DIOX_N PF14226.6 KIY52436.1 - 1.6e-27 96.6 0.0 2.4e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY52436.1 - 2.1e-18 66.6 0.0 3.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Disaggr_repeat PF06848.11 KIY52436.1 - 0.044 13.5 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Disaggregatase related repeat MFS_1 PF07690.16 KIY52437.1 - 1.3e-49 169.0 13.9 1.3e-49 169.0 13.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY52437.1 - 3.2e-10 39.4 23.6 8.3e-10 38.1 2.9 3.0 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KIY52437.1 - 0.00074 17.9 0.1 0.00074 17.9 0.1 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_2 PF00891.18 KIY52438.1 - 2.1e-14 53.4 0.0 4.4e-05 22.9 0.0 3.2 3 0 0 3 3 3 3 O-methyltransferase domain HTH_IclR PF09339.10 KIY52438.1 - 0.00061 19.5 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIY52438.1 - 0.0031 17.4 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 MarR family MTS PF05175.14 KIY52438.1 - 0.051 13.1 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HTH_29 PF13551.6 KIY52438.1 - 0.087 12.9 0.0 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix RPA_C PF08784.11 KIY52438.1 - 0.11 13.2 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal SelB-wing_1 PF09105.10 KIY52438.1 - 0.17 11.9 0.1 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor SelB, winged helix TnsD PF15978.5 KIY52438.1 - 0.27 10.2 0.0 0.39 9.7 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Aldo_ket_red PF00248.21 KIY52439.1 - 4.2e-48 164.1 0.0 8.1e-47 159.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 KIY52440.1 - 6.6e-11 41.9 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KIY52440.1 - 0.01 16.1 0.2 0.029 14.7 0.2 1.8 1 0 0 1 1 1 0 PWI domain Sad1_UNC PF07738.13 KIY52441.1 - 3.1e-26 91.9 0.0 5.6e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal TPR_MLP1_2 PF07926.12 KIY52441.1 - 0.053 13.6 0.4 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein NAD_binding_9 PF13454.6 KIY52442.1 - 0.0073 16.3 0.0 0.04 13.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding EB1 PF03271.17 KIY52443.1 - 7.1e-13 48.6 2.8 7.1e-13 48.6 2.8 1.8 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KIY52443.1 - 2.1e-06 27.9 0.3 3.3e-06 27.2 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 KIY52443.1 - 0.0044 15.6 0.1 0.0058 15.2 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like TSC22 PF01166.18 KIY52443.1 - 0.023 15.0 1.2 0.05 13.9 1.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family FlxA PF14282.6 KIY52443.1 - 0.034 14.1 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 FlxA-like protein HXXSHH PF07586.11 KIY52443.1 - 0.046 13.3 0.6 0.85 9.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) CH_2 PF06294.11 KIY52443.1 - 0.055 13.6 0.2 0.091 12.9 0.2 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein Pyr_redox_2 PF07992.14 KIY52446.1 - 8.3e-06 25.2 0.0 1.5e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY52446.1 - 0.00022 21.2 0.0 0.0085 16.1 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KIY52446.1 - 0.0095 15.1 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.16 KIY52448.1 - 3.4e-21 75.6 63.0 1.3e-19 70.4 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.6 KIY52448.1 - 5.2 7.4 12.1 10 6.5 4.6 3.2 3 1 0 3 3 3 0 Stage V sporulation protein AB Rot1 PF10681.9 KIY52449.1 - 5.7e-53 179.5 3.0 6.4e-53 179.4 3.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Proteasome PF00227.26 KIY52450.1 - 8.6e-31 106.9 0.0 9.9e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit SLAC1 PF03595.17 KIY52451.1 - 1.6e-50 172.2 36.9 1.9e-50 172.0 36.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HIT PF01230.23 KIY52452.1 - 7.4e-23 81.1 0.6 9e-23 80.9 0.1 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KIY52452.1 - 7.1e-09 36.2 0.3 1e-08 35.6 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIY52452.1 - 3.5e-05 23.7 0.0 5.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF1161 PF06649.12 KIY52452.1 - 0.17 12.1 0.1 1.2 9.4 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1161) COesterase PF00135.28 KIY52453.1 - 2.9e-96 323.4 0.0 1e-94 318.3 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIY52453.1 - 6.1e-05 22.6 0.9 0.0027 17.2 0.5 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIY52453.1 - 0.0001 22.2 0.0 0.00073 19.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KIY52454.1 - 1.7e-27 96.3 63.8 8e-21 74.3 40.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HRG PF16954.5 KIY52454.1 - 0.074 13.5 0.9 0.074 13.5 0.9 3.7 3 2 1 4 4 4 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene NFACT-R_1 PF05670.13 KIY52455.1 - 9.4e-41 138.9 0.1 2.2e-40 137.7 0.0 1.7 2 0 0 2 2 2 1 NFACT protein RNA binding domain Methyltransf_25 PF13649.6 KIY52456.1 - 7.7e-13 49.0 0.1 3.9e-12 46.7 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY52456.1 - 1.9e-12 47.2 0.0 4.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIY52456.1 - 2.7e-12 46.7 0.2 4.6e-12 45.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KIY52456.1 - 6.1e-12 46.0 0.0 5.2e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY52456.1 - 2.2e-07 30.9 0.0 3.6e-06 26.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY52456.1 - 5.1e-07 29.4 0.0 8.8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KIY52456.1 - 1.1e-06 29.3 0.0 3.2e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KIY52456.1 - 0.00014 21.4 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 KIY52456.1 - 0.00014 21.8 0.1 0.00026 20.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KIY52456.1 - 0.00023 21.0 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.11 KIY52456.1 - 0.00027 19.9 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 KIY52456.1 - 0.018 16.1 0.0 0.093 13.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KIY52456.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 KIY52456.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KIY52456.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KIY52456.1 - 0.18 11.6 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 KIY52456.1 - 0.21 10.9 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TPR_1 PF00515.28 KIY52457.1 - 2.7e-30 102.9 6.7 5.2e-06 26.1 0.1 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIY52457.1 - 1.7e-28 96.4 21.5 2.2e-06 27.4 0.1 10.7 11 0 0 11 11 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KIY52457.1 - 1e-27 96.4 40.3 0.00014 22.3 1.6 10.8 10 2 1 12 12 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIY52457.1 - 8.1e-20 69.3 6.5 1.1e-05 25.2 0.0 9.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY52457.1 - 2.3e-19 68.4 38.6 5.3e-06 26.8 0.1 12.2 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIY52457.1 - 2.7e-16 59.6 37.0 2.3e-07 31.0 2.2 9.9 7 2 2 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KIY52457.1 - 3.1e-15 56.5 34.7 1.5e-05 25.5 1.4 10.2 8 2 2 10 10 10 6 Tetratricopeptide repeat TPR_6 PF13174.6 KIY52457.1 - 2.3e-14 53.0 25.8 9.2e-07 29.1 0.0 11.6 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIY52457.1 - 1.5e-10 40.3 16.5 0.0045 16.9 0.1 8.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIY52457.1 - 9.9e-09 34.8 30.8 0.11 12.4 0.3 9.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIY52457.1 - 1.9e-08 34.1 11.3 0.63 10.5 0.0 9.4 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY52457.1 - 9.7e-06 25.7 9.9 0.098 12.8 0.1 6.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY52457.1 - 1.2e-05 24.9 10.8 0.99 9.2 0.1 7.6 7 1 1 8 8 8 3 TPR repeat Fis1_TPR_C PF14853.6 KIY52457.1 - 0.054 13.6 4.5 1.5 9.0 0.3 4.9 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KIY52457.1 - 0.062 12.3 0.1 0.18 10.8 0.1 1.7 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) HAT PF02184.16 KIY52457.1 - 0.46 10.5 3.3 21 5.2 0.0 3.3 3 0 0 3 3 2 0 HAT (Half-A-TPR) repeat TPR_4 PF07721.14 KIY52457.1 - 0.52 11.1 0.0 0.52 11.1 0.0 5.7 6 0 0 6 6 3 0 Tetratricopeptide repeat NARP1 PF12569.8 KIY52457.1 - 5.3 5.8 33.5 0.11 11.4 1.9 3.7 3 1 0 3 3 3 0 NMDA receptor-regulated protein 1 COesterase PF00135.28 KIY52459.1 - 4e-96 322.9 0.0 6.5e-95 318.9 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIY52459.1 - 0.00035 20.1 1.0 0.00097 18.7 1.1 1.6 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIY52459.1 - 0.00042 20.2 0.0 0.0022 17.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PcfK PF14058.6 KIY52459.1 - 0.007 16.6 0.5 2.3 8.5 0.1 2.3 1 1 0 2 2 2 2 PcfK-like protein TPR_19 PF14559.6 KIY52460.1 - 4.6e-08 33.5 16.9 0.0004 20.8 1.7 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY52460.1 - 3.2e-07 30.6 6.2 7.8e-05 23.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY52460.1 - 2.2e-06 27.4 6.1 2.9e-06 27.0 0.1 3.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY52460.1 - 3.9e-06 26.5 10.1 6.7e-06 25.8 0.1 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY52460.1 - 4.5e-06 26.9 2.5 4.5e-06 26.9 2.5 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY52460.1 - 6.9e-06 25.7 5.2 1.3e-05 24.8 0.1 3.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY52460.1 - 1.6e-05 25.5 13.9 0.00026 21.6 1.2 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY52460.1 - 1.7e-05 24.5 5.5 0.00077 19.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIY52460.1 - 2e-05 24.6 0.5 0.3 11.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY52460.1 - 0.00042 20.9 11.6 0.0041 17.8 0.0 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIY52460.1 - 0.0016 18.3 6.0 0.019 14.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 KIY52460.1 - 0.02 14.6 8.0 1.4 8.6 1.5 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KIY52460.1 - 0.076 13.7 10.4 0.11 13.1 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat RPN6_N PF18055.1 KIY52460.1 - 0.14 12.5 1.0 0.56 10.6 0.4 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain HAT PF02184.16 KIY52460.1 - 0.16 12.0 0.8 5.6 7.0 0.2 2.6 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_11 PF13414.6 KIY52460.1 - 0.25 11.1 4.2 0.72 9.6 0.1 3.4 3 1 1 4 4 4 0 TPR repeat COesterase PF00135.28 KIY52465.1 - 3.8e-70 237.2 0.0 6.9e-69 233.1 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIY52465.1 - 7.6e-05 22.3 0.7 0.00058 19.4 1.0 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIY52465.1 - 0.001 19.0 0.0 0.0046 16.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold TT_ORF1 PF02956.14 KIY52465.1 - 0.15 10.7 0.1 0.23 10.1 0.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 PX PF00787.24 KIY52466.1 - 1.6e-25 89.3 0.0 1.9e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 PX domain ENTH PF01417.20 KIY52467.1 - 5.4e-42 142.8 0.2 6.3e-42 142.6 0.2 1.0 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KIY52467.1 - 3e-05 23.2 0.2 3.2e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KIY52467.1 - 0.031 14.1 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 VHS domain Glyco_tran_28_C PF04101.16 KIY52469.1 - 4.8e-23 81.9 0.0 9.7e-23 81.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Trehalase PF01204.18 KIY52470.1 - 3.6e-110 369.2 0.4 1e-97 328.1 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 KIY52470.1 - 0.051 12.5 0.0 0.098 11.6 0.0 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase SWI-SNF_Ssr4 PF08549.10 KIY52471.1 - 2e-23 83.0 0.0 2e-23 83.0 0.0 1.4 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1750) Orexin PF02072.15 KIY52471.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Prepro-orexin CG-1 PF03859.16 KIY52471.1 - 0.17 11.7 0.0 0.59 9.9 0.0 1.8 1 1 0 1 1 1 0 CG-1 domain zf-CCCH_2 PF14608.6 KIY52474.1 - 0.28 11.7 2.1 0.49 10.9 2.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger F-box-like PF12937.7 KIY52475.1 - 0.0096 15.8 0.2 0.031 14.2 0.2 1.9 1 0 0 1 1 1 1 F-box-like UQ_con PF00179.26 KIY52476.1 - 7.3e-42 142.3 0.0 9e-42 142.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KIY52476.1 - 1.9e-18 66.0 0.1 1.9e-18 66.0 0.1 1.6 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 KIY52476.1 - 0.0051 16.7 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Prok-E2_B PF14461.6 KIY52476.1 - 0.0086 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.31 KIY52476.1 - 0.038 13.9 0.1 0.076 12.9 0.1 1.5 1 0 0 1 1 1 0 UBA/TS-N domain ArfGap PF01412.18 KIY52477.1 - 1.1e-33 115.8 0.4 1.1e-33 115.8 0.4 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Clat_adaptor_s PF01217.20 KIY52478.1 - 1.1e-56 190.7 3.2 1.2e-56 190.6 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 KIY52478.1 - 0.032 13.8 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain F-box-like PF12937.7 KIY52479.1 - 0.0019 18.0 0.0 0.0075 16.1 0.0 2.1 1 1 0 1 1 1 1 F-box-like CsbD PF05532.12 KIY52480.1 - 1.7e-12 47.1 14.3 7e-07 29.1 1.4 2.4 1 1 1 2 2 2 2 CsbD-like LemA PF04011.12 KIY52480.1 - 0.0051 16.7 0.2 0.0063 16.4 0.2 1.2 1 0 0 1 1 1 1 LemA family MAR_sialic_bdg PF10564.9 KIY52481.1 - 0.037 14.1 0.1 0.066 13.3 0.1 1.3 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat CDH-cyt PF16010.5 KIY52484.1 - 8.6e-56 188.5 0.8 1e-55 188.2 0.8 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase CDH-cyt PF16010.5 KIY52485.1 - 2.4e-52 177.3 0.0 3.2e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KIY52485.1 - 0.12 12.6 1.0 0.35 11.1 0.0 2.2 3 0 0 3 3 3 0 DOMON domain ABC2_membrane PF01061.24 KIY52486.1 - 4.5e-75 251.7 61.6 5.7e-44 150.1 25.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KIY52486.1 - 3.1e-35 119.9 1.9 7.1e-29 99.6 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KIY52486.1 - 9.5e-34 116.9 0.0 7.6e-16 58.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KIY52486.1 - 7.1e-13 49.0 0.0 1.5e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KIY52486.1 - 7.3e-08 32.5 0.1 1.6e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KIY52486.1 - 2.5e-07 31.3 0.1 0.00012 22.5 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY52486.1 - 3.1e-05 24.3 0.1 0.052 13.8 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIY52486.1 - 4e-05 23.3 0.0 0.004 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KIY52486.1 - 0.00042 20.4 0.0 0.75 9.9 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY52486.1 - 0.001 19.6 0.0 0.77 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY52486.1 - 0.0014 18.8 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 KIY52486.1 - 0.0059 17.0 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY52486.1 - 0.0082 16.1 0.0 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KIY52486.1 - 0.0083 15.9 0.1 0.17 11.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY52486.1 - 0.014 15.2 0.3 0.26 11.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY52486.1 - 0.033 14.0 0.0 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KIY52486.1 - 0.045 13.3 0.4 1.5 8.4 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KIY52486.1 - 0.062 13.5 0.1 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 KIY52486.1 - 0.07 13.0 0.0 0.78 9.6 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase Arf PF00025.21 KIY52486.1 - 0.13 11.7 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family TsaE PF02367.17 KIY52486.1 - 0.14 12.2 0.4 0.51 10.4 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIY52486.1 - 0.16 12.3 0.0 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 KIY52486.1 - 0.2 12.1 0.1 0.39 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain FMN_dh PF01070.18 KIY52489.1 - 5.2e-108 361.2 0.0 6.6e-108 360.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 KIY52489.1 - 3.1e-05 23.4 0.0 0.3 10.3 0.0 2.9 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KIY52489.1 - 4.1e-05 22.8 0.8 0.0017 17.4 0.3 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KIY52489.1 - 6.5e-05 22.2 0.0 9.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Chitin_synth_1 PF01644.17 KIY52490.1 - 2.8e-80 268.0 0.1 4.4e-80 267.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIY52490.1 - 1.7e-28 98.4 0.1 3.6e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIY52490.1 - 1e-23 83.8 0.2 3.6e-17 62.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY52490.1 - 0.0024 17.8 10.2 0.0024 17.8 10.2 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 GKAP PF03359.13 KIY52491.1 - 0.12 12.0 0.2 0.16 11.5 0.2 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein AA_permease_2 PF13520.6 KIY52496.1 - 4e-46 157.7 52.6 5.5e-46 157.3 52.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY52496.1 - 3.3e-22 78.7 46.7 5.8e-22 77.9 46.7 1.3 1 0 0 1 1 1 1 Amino acid permease CPBP PF02517.16 KIY52499.1 - 4.5e-17 62.2 4.7 4.5e-17 62.2 4.7 3.1 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Pro_isomerase PF00160.21 KIY52500.1 - 3.5e-49 167.1 0.2 3.9e-49 167.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F1F0-ATPsyn_F PF10791.9 KIY52501.1 - 2.9e-29 101.4 0.0 3.6e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi DUF4239 PF14023.6 KIY52502.1 - 1.4 8.6 3.8 0.76 9.5 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Retrotran_gag_2 PF14223.6 KIY52503.1 - 0.00091 18.9 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF5349 PF17298.2 KIY52503.1 - 5.8 6.6 5.0 8.1 6.1 5.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Transposase_21 PF02992.14 KIY52505.1 - 0.049 12.9 1.7 0.059 12.6 0.0 1.9 2 1 0 2 2 2 0 Transposase family tnp2 Cas9_PI2 PF18070.1 KIY52506.1 - 0.12 13.1 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 CRISPR-Cas9 PI domain DUF4218 PF13960.6 KIY52507.1 - 0.036 13.7 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Pombe_5TM PF09437.10 KIY52511.1 - 0.011 15.3 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Pombe specific 5TM protein HTH_Tnp_Tc3_2 PF01498.18 KIY52511.1 - 0.03 14.6 0.0 0.033 14.4 0.0 1.1 1 0 0 1 1 1 0 Transposase Raf1_HTH PF18579.1 KIY52511.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Zn_clus PF00172.18 KIY52515.1 - 0.08 13.1 2.5 0.16 12.1 2.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HIG_1_N PF04588.13 KIY52517.1 - 0.0013 18.9 2.6 0.0045 17.2 2.3 2.0 1 1 1 2 2 2 2 Hypoxia induced protein conserved region DUF4491 PF14898.6 KIY52517.1 - 0.1 13.1 0.3 0.18 12.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Olduvai PF06758.13 KIY52517.1 - 0.8 10.0 4.2 0.42 10.9 1.5 1.9 2 0 0 2 2 2 0 Olduvai domain NmrA PF05368.13 KIY52518.1 - 3.2e-29 102.1 0.0 4e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY52518.1 - 5.6e-10 39.4 0.0 9.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Fasciclin PF02469.22 KIY52519.1 - 5.4e-09 36.4 0.0 8.5e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Fasciclin domain DUF4729 PF15866.5 KIY52520.1 - 0.0012 18.2 1.5 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4729) zf-C2H2_aberr PF17017.5 KIY52520.1 - 0.051 13.7 1.5 0.091 12.9 1.5 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger zf-Di19 PF05605.12 KIY52520.1 - 0.23 11.8 0.0 0.23 11.8 0.0 3.3 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-TAZ PF02135.16 KIY52520.1 - 2.1 8.8 12.9 2.1 8.9 7.4 2.3 1 1 1 2 2 2 0 TAZ zinc finger zf-H2C2_5 PF13909.6 KIY52520.1 - 3.8 7.3 20.7 0.5 10.2 0.3 3.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain Phage_integrase PF00589.22 KIY52523.1 - 0.0038 17.0 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Plavaka PF18759.1 KIY52525.1 - 2.6e-17 63.0 0.9 3.5e-17 62.6 0.9 1.2 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY52526.1 - 8.9e-85 284.8 0.1 9.9e-85 284.6 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase NIR_SIR PF01077.22 KIY52527.1 - 2.8e-32 111.4 0.0 4.4e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KIY52527.1 - 5.3e-11 42.2 0.0 9.7e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain GPI-anchored PF10342.9 KIY52528.1 - 2.1e-06 28.4 2.8 2.4e-06 28.2 2.8 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tet_JBP PF12851.7 KIY52529.1 - 0.00042 19.8 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Taq-exonuc PF09281.10 KIY52530.1 - 0.43 10.6 4.4 1.2 9.2 4.4 1.7 1 0 0 1 1 1 0 Taq polymerase, exonuclease KDZ PF18758.1 KIY52531.1 - 4.3e-38 131.1 1.0 1.3e-18 67.4 0.1 2.2 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase DUF1708 PF08101.11 KIY52532.1 - 2.6e-06 26.8 0.0 8.8e-06 25.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) SR-25 PF10500.9 KIY52532.1 - 6.6 6.3 18.9 0.23 11.0 10.1 2.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Lipase_3 PF01764.25 KIY52535.1 - 5.8e-24 84.6 0.0 7.3e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY52535.1 - 0.0011 19.6 0.2 0.0014 19.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KIY52535.1 - 0.0091 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 KIY52535.1 - 0.027 14.0 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 KIY52535.1 - 0.04 13.5 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KIY52535.1 - 0.067 12.4 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KIY52535.1 - 0.07 12.8 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF1996 PF09362.10 KIY52536.1 - 2.3e-76 256.8 2.4 3.9e-76 256.1 2.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MFS_1 PF07690.16 KIY52538.1 - 8e-22 77.6 23.6 8e-22 77.6 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 KIY52540.1 - 1.2e-18 68.0 0.0 2.6e-17 63.7 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY52540.1 - 1.2e-13 51.4 0.0 2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KIY52541.1 - 8.5e-12 45.8 0.0 1.5e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_3 PF07859.13 KIY52542.1 - 6.4e-17 62.1 0.0 9e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY52542.1 - 9.4e-14 51.0 0.0 1.7e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase DEAD PF00270.29 KIY52543.1 - 3.3e-16 59.5 0.0 4e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 KIY52543.1 - 0.015 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SKA1 PF07160.12 KIY52544.1 - 0.42 10.4 4.6 1.8 8.4 0.9 2.0 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 UPF0242 PF06785.11 KIY52544.1 - 1.8 8.6 5.6 2.7 8.1 5.6 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Retrotrans_gag PF03732.17 KIY52545.1 - 0.00022 21.4 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4233 PF14017.6 KIY52546.1 - 0.034 14.5 0.3 0.049 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Methyltransf_2 PF00891.18 KIY52547.1 - 1.4e-21 76.7 0.0 1.2e-18 67.1 0.0 2.6 3 0 0 3 3 3 2 O-methyltransferase domain HTH_29 PF13551.6 KIY52547.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Methyltransf_31 PF13847.6 KIY52547.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIY52547.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIY52547.1 - 0.09 13.5 0.0 0.3 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain HTH_IclR PF09339.10 KIY52547.1 - 0.12 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Methyltransf_25 PF13649.6 KIY52547.1 - 0.14 12.9 0.0 0.27 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MarR_2 PF12802.7 KIY52547.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 MarR family ABC_membrane PF00664.23 KIY52548.1 - 1.7e-76 257.5 24.2 5.7e-44 150.8 8.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY52548.1 - 6.9e-61 204.7 0.0 2e-29 102.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIY52548.1 - 3.9e-14 53.2 0.1 0.013 15.3 0.1 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY52548.1 - 3.3e-13 49.6 2.2 0.00013 21.5 0.0 4.7 4 1 0 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY52548.1 - 3.2e-10 40.7 0.6 0.00072 20.0 0.1 3.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KIY52548.1 - 6.6e-07 29.1 0.0 0.012 15.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KIY52548.1 - 7.1e-07 29.6 1.1 0.015 15.5 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY52548.1 - 1e-06 28.4 0.2 0.045 13.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KIY52548.1 - 1.3e-06 27.9 0.2 0.0079 15.5 0.1 3.4 2 1 1 3 3 3 2 Zeta toxin AAA_33 PF13671.6 KIY52548.1 - 2e-06 28.1 0.4 0.082 13.1 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIY52548.1 - 2e-06 28.4 0.0 0.05 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KIY52548.1 - 6.2e-06 25.3 0.3 0.0045 15.8 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 KIY52548.1 - 1.3e-05 25.0 0.3 0.13 12.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIY52548.1 - 2.9e-05 24.0 0.0 0.41 10.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 KIY52548.1 - 7.3e-05 22.6 0.1 0.88 9.3 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_28 PF13521.6 KIY52548.1 - 9.9e-05 22.6 0.0 0.096 12.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIY52548.1 - 0.0001 22.9 0.2 0.52 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KIY52548.1 - 0.00022 21.2 0.0 1.3 9.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KIY52548.1 - 0.00097 19.1 0.2 1.9 8.3 0.0 2.9 3 0 0 3 3 2 2 Adenylylsulphate kinase G-alpha PF00503.20 KIY52548.1 - 0.0014 17.9 0.0 0.54 9.4 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.12 KIY52548.1 - 0.0019 18.2 0.6 0.89 9.4 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 KIY52548.1 - 0.0027 17.5 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KIY52548.1 - 0.0029 17.0 0.0 2.7 7.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KIY52548.1 - 0.0038 17.0 0.0 0.4 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KIY52548.1 - 0.004 17.3 2.2 0.71 9.9 0.2 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain CPT PF07931.12 KIY52548.1 - 0.0055 16.6 0.1 4.5 7.1 0.0 2.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 KIY52548.1 - 0.0093 15.2 0.4 1.3 8.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 KIY52548.1 - 0.011 15.1 0.1 5.7 6.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KIY52548.1 - 0.013 15.9 0.0 5.7 7.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF4245 PF14030.6 KIY52548.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF4245) PRK PF00485.18 KIY52548.1 - 0.016 15.0 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 KIY52548.1 - 0.019 15.0 0.4 9.8 6.2 0.1 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activ_2 PF14532.6 KIY52548.1 - 0.03 14.5 0.0 8.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KIY52548.1 - 0.032 14.0 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 KIY52548.1 - 0.037 14.3 0.1 6.5 7.1 0.0 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KIY52548.1 - 0.046 13.7 0.0 7 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KIY52548.1 - 0.053 12.9 0.3 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KIY52548.1 - 0.065 13.7 0.4 19 5.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 KIY52548.1 - 0.1 12.5 0.7 18 5.2 0.0 3.2 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 DUF2075 PF09848.9 KIY52548.1 - 0.1 11.8 0.1 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KIY52548.1 - 0.13 12.0 0.0 22 4.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 KIY52548.1 - 0.15 12.2 0.0 19 5.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 KIY52548.1 - 0.17 12.1 0.0 20 5.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KIY52548.1 - 0.18 11.5 0.2 24 4.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.6 KIY52548.1 - 0.23 10.1 0.0 11 4.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Ceramidase_alk PF04734.13 KIY52549.1 - 1.1e-208 694.0 0.1 1.3e-208 693.7 0.1 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KIY52549.1 - 1.1e-56 191.3 0.0 2e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal NAD_binding_5 PF07994.12 KIY52550.1 - 2e-137 457.9 0.0 2.5e-137 457.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KIY52550.1 - 8.4e-45 151.5 0.0 1.8e-44 150.5 0.0 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Ribosomal_L32e PF01655.18 KIY52554.1 - 6.9e-48 161.6 0.9 8e-48 161.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase PF00069.25 KIY52555.1 - 2.8e-41 141.6 0.0 1.7e-35 122.7 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52555.1 - 1.1e-19 70.7 0.0 9.4e-17 61.1 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY52555.1 - 1.9e-05 24.2 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY52555.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY52555.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY52555.1 - 0.034 12.9 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KIY52555.1 - 0.052 13.1 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KIY52555.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 GTP_EFTU PF00009.27 KIY52556.1 - 2.7e-54 183.7 0.1 4.7e-54 182.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIY52556.1 - 1.5e-42 144.4 0.0 2.9e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KIY52556.1 - 0.00076 19.5 0.2 0.028 14.5 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Thiolase_N PF00108.23 KIY52557.1 - 6.1e-62 209.3 0.0 9.6e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY52557.1 - 2.4e-37 127.3 1.9 6.2e-37 126.0 1.9 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIY52557.1 - 0.0014 18.2 0.6 0.0014 18.2 0.6 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ldh_1_C PF02866.18 KIY52557.1 - 0.035 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain ACP_syn_III_C PF08541.10 KIY52557.1 - 0.075 13.2 0.1 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal tRNA-synt_1d PF00750.19 KIY52558.1 - 2.1e-99 332.8 5.7 3e-99 332.3 5.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KIY52558.1 - 2.4e-19 69.6 0.0 4.9e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain UxaE PF16257.5 KIY52558.1 - 0.0021 16.8 3.1 0.018 13.7 0.3 2.1 1 1 0 2 2 2 2 tagaturonate epimerase tRNA-synt_1g PF09334.11 KIY52558.1 - 0.0096 14.7 0.6 0.31 9.8 0.1 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) Ribosomal_S3_C PF00189.20 KIY52560.1 - 4.5e-25 88.0 0.1 1.5e-24 86.3 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KIY52560.1 - 3.2e-11 42.9 0.1 7.8e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 KH domain UN_NPL4 PF11543.8 KIY52560.1 - 0.027 14.9 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KIY52560.1 - 0.081 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus Lyase_8 PF02278.18 KIY52561.1 - 8e-67 225.4 2.9 1.2e-66 224.8 2.9 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KIY52561.1 - 1.5e-19 70.1 0.0 2.6e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KIY52561.1 - 2.1e-15 56.9 1.0 4.9e-15 55.8 1.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain RVT_thumb PF06817.14 KIY52562.1 - 0.03 14.2 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Plavaka PF18759.1 KIY52565.1 - 3.6e-30 105.3 0.1 4.8e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Med26 PF08711.11 KIY52566.1 - 0.00023 21.1 0.5 0.00041 20.3 0.5 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PAP1 PF08601.10 KIY52567.1 - 0.21 11.3 1.0 0.38 10.4 1.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Toxin-JAB1 PF15659.6 KIY52568.1 - 0.11 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 JAB-like toxin 1 ALG11_N PF15924.5 KIY52569.1 - 1.1e-79 267.4 2.6 3.2e-79 265.8 2.6 1.7 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KIY52569.1 - 4.4e-24 84.9 0.0 6.6e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIY52569.1 - 4.3e-12 46.6 0.0 1.5e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIY52569.1 - 0.0075 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 baeRF_family10 PF18854.1 KIY52569.1 - 0.093 13.0 0.3 0.18 12.0 0.3 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 PMT PF02366.18 KIY52570.1 - 1.9e-81 273.3 15.1 2.4e-81 272.9 15.1 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 KIY52570.1 - 2.1e-20 73.3 1.5 3.5e-20 72.6 1.5 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KIY52570.1 - 4.8e-07 30.1 9.8 4.8e-07 30.1 9.8 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1240 PF06836.12 KIY52570.1 - 0.11 13.1 0.2 11 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) ALG11_N PF15924.5 KIY52573.1 - 2e-47 162.0 2.7 4.7e-35 121.5 0.0 2.1 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KIY52573.1 - 5.2e-05 22.9 0.0 8.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 PMT PF02366.18 KIY52574.1 - 2.8e-81 272.7 14.9 4.9e-81 271.9 14.9 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIY52574.1 - 2.8e-65 219.7 11.4 2.8e-65 219.7 11.4 2.0 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIY52574.1 - 2.1e-39 135.3 0.9 3.4e-39 134.6 0.9 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KIY52574.1 - 4e-07 30.4 8.0 4e-07 30.4 8.0 3.2 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1240 PF06836.12 KIY52574.1 - 1.3 9.6 4.9 18 5.9 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) Ric8 PF10165.9 KIY52575.1 - 6.4e-97 325.5 0.0 8.2e-97 325.1 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn cobW PF02492.19 KIY52576.1 - 1.7e-40 138.5 0.0 3.2e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KIY52576.1 - 0.00045 20.1 0.0 0.00083 19.2 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KIY52576.1 - 0.0046 16.9 0.1 0.46 10.4 0.0 2.6 2 2 0 2 2 2 1 RsgA GTPase MobB PF03205.14 KIY52576.1 - 0.0055 16.6 0.1 0.035 14.0 0.0 2.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Mito_carr PF00153.27 KIY52577.1 - 2.8e-62 206.7 5.5 2.9e-21 75.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 KIY52578.1 - 3.8e-50 171.0 0.0 5e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FlbD PF06289.11 KIY52578.1 - 0.045 13.4 0.0 0.59 9.8 0.0 2.5 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins LIM_bind PF01803.16 KIY52579.1 - 1.6e-30 106.5 0.0 1.7e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 LIM-domain binding protein DNA_ligase_aden PF01653.18 KIY52579.1 - 0.24 10.4 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain CRAL_TRIO PF00650.20 KIY52580.1 - 1.3e-34 119.2 0.0 1.7e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY52580.1 - 5.6e-09 36.0 0.4 1.2e-08 35.0 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FAD_binding_3 PF01494.19 KIY52581.1 - 1.8e-16 60.3 0.0 9.5e-16 58.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY52581.1 - 4.9e-08 32.6 0.0 0.00012 21.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY52581.1 - 7.4e-08 32.4 0.2 8.7e-06 25.5 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY52581.1 - 8.8e-07 29.1 2.1 1.4e-06 28.4 0.1 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIY52581.1 - 1.3e-06 27.4 0.1 1.6e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KIY52581.1 - 1.4e-06 27.7 0.1 2.1e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KIY52581.1 - 2.1e-06 28.2 0.0 0.0049 17.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY52581.1 - 0.00024 20.5 0.1 0.0032 16.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY52581.1 - 0.00069 19.1 0.3 0.0026 17.2 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIY52581.1 - 0.0025 16.9 0.5 0.027 13.5 0.5 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KIY52581.1 - 0.0042 16.2 0.1 0.04 13.0 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KIY52581.1 - 0.006 15.5 0.0 0.62 8.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KIY52581.1 - 0.0066 15.7 0.4 0.096 11.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KIY52581.1 - 0.011 15.0 0.2 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KIY52581.1 - 0.029 13.7 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KIY52581.1 - 0.18 11.8 1.3 2.9 7.9 1.4 2.7 1 1 1 2 2 2 0 FAD-NAD(P)-binding Glyco_hydro_47 PF01532.20 KIY52582.1 - 2e-128 429.2 0.0 2.3e-128 429.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Spherulin4 PF12138.8 KIY52583.1 - 1.6e-50 172.0 1.5 1.8e-50 171.8 1.5 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Peptidase_S9_N PF02897.15 KIY52584.1 - 4.5e-84 282.6 1.0 6.1e-84 282.2 1.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KIY52584.1 - 4.3e-53 179.9 0.0 7.5e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIY52584.1 - 0.014 15.3 4.0 0.026 14.4 1.2 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold Sortase PF04203.13 KIY52584.1 - 0.15 11.9 0.0 5.1 6.9 0.0 2.5 1 1 1 2 2 2 0 Sortase domain Dimer_Tnp_hAT PF05699.14 KIY52587.1 - 1.5e-07 31.1 0.1 1.7e-07 31.0 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Atg8 PF02991.16 KIY52589.1 - 0.019 15.1 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Phi_1 PF04674.12 KIY52590.1 - 0.089 12.1 0.0 0.089 12.1 0.0 1.0 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region TACC_C PF05010.14 KIY52591.1 - 0.091 12.5 15.1 0.88 9.3 2.4 3.1 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Exonuc_VII_L PF02601.15 KIY52591.1 - 1.2 8.6 12.5 0.42 10.1 3.0 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 KIY52591.1 - 3.9 7.7 19.5 1 9.5 5.3 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Vac7 PF12751.7 KIY52592.1 - 0.018 14.5 3.0 0.025 14.0 3.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Pkinase_fungal PF17667.1 KIY52593.1 - 0.0071 15.2 0.1 0.025 13.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Afaf PF15339.6 KIY52594.1 - 0.094 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor Abhydrolase_9_N PF15420.6 KIY52596.1 - 0.53 10.2 5.6 0.85 9.6 5.6 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus ADH_zinc_N PF00107.26 KIY52598.1 - 6.7e-21 74.6 0.3 1.4e-20 73.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY52598.1 - 3.4e-12 47.6 0.2 3.1e-11 44.5 0.1 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY52598.1 - 2.9e-09 36.8 0.0 1.6e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIY52598.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glycos_transf_1 PF00534.20 KIY52600.1 - 7.8e-26 90.6 0.0 1.8e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIY52600.1 - 4e-22 79.1 0.4 1e-21 77.7 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIY52600.1 - 1.4e-17 64.2 0.1 4.1e-17 62.7 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIY52600.1 - 1.3e-08 35.4 0.0 1.3e-08 35.4 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIY52600.1 - 0.0069 16.7 0.0 0.039 14.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro81C PF17652.1 KIY52601.1 - 1.5e-15 57.3 0.0 2.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain F-box-like PF12937.7 KIY52602.1 - 1.5e-06 28.0 0.5 5e-06 26.3 0.5 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY52602.1 - 0.17 12.4 1.7 39 4.9 0.0 4.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY52602.1 - 2 8.4 6.0 3.3 7.7 1.2 3.4 3 1 0 3 3 3 0 F-box domain AA_permease_2 PF13520.6 KIY52604.1 - 1.7e-62 211.6 53.6 2.3e-62 211.2 53.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY52604.1 - 1e-12 47.5 44.6 1.6e-12 46.8 44.6 1.3 1 0 0 1 1 1 1 Amino acid permease Not3 PF04065.15 KIY52605.1 - 0.23 10.9 0.2 0.36 10.2 0.2 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Phage_integrase PF00589.22 KIY52607.1 - 0.004 17.0 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family ABC_membrane PF00664.23 KIY52609.1 - 6.6e-09 35.8 3.2 1.5e-08 34.6 3.2 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region RRM_1 PF00076.22 KIY52610.1 - 2.8e-19 68.7 0.0 5.3e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY52610.1 - 1.8e-05 24.8 0.0 4.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KIY52610.1 - 0.00032 20.3 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIY52610.1 - 0.052 13.6 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1314 PF07013.11 KIY52610.1 - 0.2 11.5 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Presenilin PF01080.17 KIY52610.1 - 0.53 9.0 4.6 0.62 8.8 4.6 1.0 1 0 0 1 1 1 0 Presenilin SseC PF04888.12 KIY52610.1 - 2.8 7.5 6.8 3.7 7.1 6.8 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Hamartin PF04388.12 KIY52613.1 - 8.9 4.8 7.3 11 4.5 7.3 1.1 1 0 0 1 1 1 0 Hamartin protein VWA PF00092.28 KIY52614.1 - 7.3e-05 23.1 0.1 0.00013 22.2 0.1 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIY52614.1 - 0.0032 17.4 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 KIY52614.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.4 1 1 0 1 1 1 0 Copine VWA_2 PF13519.6 KIY52614.1 - 0.039 14.6 0.1 0.089 13.4 0.1 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain GatB_N PF02934.15 KIY52615.1 - 5.6e-104 347.4 0.0 7e-104 347.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KIY52615.1 - 1.6e-29 102.7 0.0 2.5e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 GatB domain DUF4553 PF15090.6 KIY52616.1 - 0.15 11.0 0.7 0.19 10.7 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) Beta_helix PF13229.6 KIY52617.1 - 6.3e-10 39.1 17.3 2e-08 34.3 16.5 2.9 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 KIY52617.1 - 3.1e-06 26.6 3.2 0.029 13.6 0.6 2.3 2 0 0 2 2 2 2 Periplasmic copper-binding protein (NosD) VSP PF03302.13 KIY52617.1 - 0.00088 18.2 1.1 0.00088 18.2 1.1 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF4381 PF14316.6 KIY52617.1 - 0.081 13.2 0.5 0.13 12.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) F-box-like PF12937.7 KIY52618.1 - 4.7e-06 26.4 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like RNA_pol_3_Rpc31 PF11705.8 KIY52618.1 - 0.028 14.7 6.5 0.043 14.1 6.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GATA PF00320.27 KIY52620.1 - 3.7e-08 32.8 4.2 6.1e-08 32.1 4.2 1.4 1 0 0 1 1 1 1 GATA zinc finger TFIIA PF03153.13 KIY52620.1 - 0.0023 18.0 19.4 0.0023 18.0 19.4 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 KIY52620.1 - 0.026 14.6 9.3 0.05 13.7 9.3 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Exonuc_VII_L PF02601.15 KIY52620.1 - 0.033 13.8 7.9 0.048 13.2 7.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 KIY52620.1 - 0.14 12.7 10.7 0.2 12.1 10.7 1.2 1 0 0 1 1 1 0 AAA domain Ureide_permease PF07168.11 KIY52620.1 - 0.29 9.9 0.2 0.41 9.3 0.2 1.1 1 0 0 1 1 1 0 Ureide permease LMBR1 PF04791.16 KIY52620.1 - 0.32 9.8 2.7 0.52 9.1 2.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ArfGap PF01412.18 KIY52620.1 - 0.38 10.8 0.1 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DUF3292 PF11696.8 KIY52620.1 - 0.56 8.5 5.2 0.78 8.0 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF3464 PF11947.8 KIY52620.1 - 0.76 9.5 4.8 1.4 8.6 4.8 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF444 PF04285.12 KIY52620.1 - 0.76 8.8 9.9 1.2 8.1 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Peptidase_U57 PF05582.12 KIY52620.1 - 1.3 8.2 6.0 2 7.6 6.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 ALMT PF11744.8 KIY52620.1 - 1.9 7.2 7.3 2.7 6.7 7.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 KIY52620.1 - 3.7 6.2 9.4 6.4 5.4 9.4 1.3 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 KIY52620.1 - 4 6.7 11.2 5.8 6.2 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 KIY52620.1 - 7 5.5 15.1 9.7 5.0 15.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.22 KIY52621.1 - 0.0016 18.2 0.0 0.16 11.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 KIY52622.1 - 8.5e-286 950.7 1.7 1e-285 950.4 1.7 1.1 1 0 0 1 1 1 1 Nop14-like family TetR_C_6 PF13977.6 KIY52622.1 - 0.04 14.1 0.3 0.18 12.0 0.3 2.1 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal Thioredoxin_4 PF13462.6 KIY52623.1 - 2.7e-07 30.9 0.0 8.3e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KIY52623.1 - 0.092 12.5 0.4 0.34 10.7 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain AMP-binding PF00501.28 KIY52624.1 - 6.4e-22 77.7 0.0 1.2e-21 76.8 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme ACPS PF01648.20 KIY52625.1 - 3.3e-14 53.0 0.0 3.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Oxidored_FMN PF00724.20 KIY52626.1 - 1.5e-65 221.7 0.0 2.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family OMPdecase PF00215.24 KIY52626.1 - 0.045 13.3 0.3 0.5 9.9 0.3 2.1 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Suv3_N PF18114.1 KIY52628.1 - 0.084 13.0 0.2 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 Suv3 helical N-terminal domain TisB_toxin PF13939.6 KIY52628.1 - 2.3 8.1 11.3 0.14 12.0 5.2 2.1 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system ABC_membrane PF00664.23 KIY52629.1 - 1.3e-76 257.8 24.4 5.1e-44 151.0 8.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY52629.1 - 2.8e-52 176.9 0.0 1.9e-28 99.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 KIY52629.1 - 8e-10 39.4 0.1 0.0027 18.1 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIY52629.1 - 9.8e-10 38.7 0.2 0.012 15.4 0.1 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY52629.1 - 8.9e-07 28.6 0.2 0.041 13.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KIY52629.1 - 1e-06 28.2 0.2 0.0079 15.5 0.1 3.4 2 1 1 3 3 3 2 Zeta toxin AAA_25 PF13481.6 KIY52629.1 - 1e-06 28.4 0.0 0.011 15.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KIY52629.1 - 1.2e-06 28.1 0.9 0.015 14.7 0.0 3.9 4 0 0 4 4 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KIY52629.1 - 1.8e-06 28.5 0.0 0.047 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KIY52629.1 - 2e-06 28.1 0.1 0.048 13.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIY52629.1 - 1.2e-05 25.5 0.0 0.22 11.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIY52629.1 - 2.9e-05 24.0 0.0 0.38 10.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KIY52629.1 - 5.2e-05 23.0 0.1 0.49 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIY52629.1 - 8.6e-05 23.1 0.2 0.49 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KIY52629.1 - 9.3e-05 22.7 0.0 0.089 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIY52629.1 - 0.00045 20.2 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KIY52629.1 - 0.00082 19.3 0.2 1.8 8.4 0.0 2.9 3 0 0 3 3 2 2 Adenylylsulphate kinase G-alpha PF00503.20 KIY52629.1 - 0.0013 18.0 0.0 0.56 9.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.12 KIY52629.1 - 0.0018 18.2 0.6 0.83 9.5 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 KIY52629.1 - 0.0024 17.7 0.0 0.64 9.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KIY52629.1 - 0.003 17.0 0.0 2.5 7.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KIY52629.1 - 0.0036 17.0 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KIY52629.1 - 0.0037 17.4 2.3 0.66 10.0 0.2 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain CPT PF07931.12 KIY52629.1 - 0.0048 16.8 0.1 4.2 7.2 0.0 2.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IstB_IS21 PF01695.17 KIY52629.1 - 0.0077 16.0 0.0 0.82 9.4 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein NB-ARC PF00931.22 KIY52629.1 - 0.0091 15.2 0.4 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 KIY52629.1 - 0.0094 15.3 0.1 5.3 6.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KIY52629.1 - 0.011 16.1 0.0 5.3 7.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF4245 PF14030.6 KIY52629.1 - 0.013 15.6 0.2 0.013 15.6 0.2 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF4245) PRK PF00485.18 KIY52629.1 - 0.016 15.0 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 KIY52629.1 - 0.017 15.1 0.4 9.2 6.3 0.1 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 KIY52629.1 - 0.027 14.2 0.1 9.9 5.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 KIY52629.1 - 0.029 14.5 0.0 7.6 6.6 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 KIY52629.1 - 0.045 13.8 0.0 6.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KIY52629.1 - 0.048 13.0 0.3 7.7 5.8 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KIY52629.1 - 0.054 13.9 0.3 17 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 KIY52629.1 - 0.079 12.9 0.7 17 5.3 0.0 3.2 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 Sigma54_activat PF00158.26 KIY52629.1 - 0.12 12.1 0.0 21 4.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SSE PF00437.20 KIY52629.1 - 0.12 11.4 0.2 0.89 8.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KIY52629.1 - 0.13 12.3 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 KIY52629.1 - 0.15 12.3 0.0 19 5.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 KIY52629.1 - 0.19 10.3 0.0 9.9 4.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KIY52629.1 - 0.26 11.0 1.0 23 4.7 0.0 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Methyltransf_2 PF00891.18 KIY52630.1 - 1.5e-21 76.7 0.0 1.2e-18 67.1 0.0 2.5 3 0 0 3 3 3 2 O-methyltransferase domain HTH_29 PF13551.6 KIY52630.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Methyltransf_31 PF13847.6 KIY52630.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIY52630.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIY52630.1 - 0.091 13.5 0.0 0.3 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain HTH_IclR PF09339.10 KIY52630.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Methyltransf_25 PF13649.6 KIY52630.1 - 0.14 12.9 0.0 0.27 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Coprogen_oxidas PF01218.18 KIY52631.1 - 0.0025 16.6 0.2 0.024 13.3 0.1 2.0 2 0 0 2 2 2 2 Coproporphyrinogen III oxidase Far-17a_AIG1 PF04750.14 KIY52632.1 - 0.013 14.8 1.4 0.018 14.4 1.1 1.4 1 1 0 1 1 1 0 FAR-17a/AIG1-like protein p450 PF00067.22 KIY52635.1 - 3.1e-58 197.7 0.0 4e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MSP1_C PF07462.11 KIY52636.1 - 0.0024 16.6 0.7 0.27 9.9 1.1 2.2 1 1 1 2 2 2 2 Merozoite surface protein 1 (MSP1) C-terminus Baculo_PEP_C PF04513.12 KIY52636.1 - 0.15 12.1 0.2 0.37 10.8 0.2 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KIY52636.1 - 0.61 10.4 3.8 0.52 10.6 1.8 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Aspzincin_M35 PF14521.6 KIY52638.1 - 0.00022 21.8 0.5 0.00043 20.9 0.5 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Metallophos PF00149.28 KIY52639.1 - 1.4e-12 48.6 3.3 5.1e-12 46.7 0.9 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SH3_1 PF00018.28 KIY52640.1 - 1.2e-12 47.3 0.1 1.9e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIY52640.1 - 2.3e-09 36.8 0.0 4.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIY52640.1 - 5.4e-09 35.8 0.0 8.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KIY52640.1 - 0.058 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain NUC153 PF08159.12 KIY52641.1 - 5.9e-16 58.0 11.2 7.8e-15 54.4 1.1 4.0 3 1 0 3 3 3 3 NUC153 domain Tom22 PF04281.13 KIY52642.1 - 1.8e-38 131.5 1.2 2e-38 131.3 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 zf-C3HC4 PF00097.25 KIY52643.1 - 1.2e-09 37.9 9.5 2e-09 37.1 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY52643.1 - 2.3e-08 34.2 9.7 3.8e-08 33.5 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY52643.1 - 9e-08 32.0 9.3 1.2e-07 31.6 6.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY52643.1 - 1.6e-07 31.1 9.2 2.9e-07 30.2 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY52643.1 - 2.1e-07 30.7 5.8 3.1e-07 30.1 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY52643.1 - 3.3e-06 27.1 10.3 6.1e-06 26.3 10.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIY52643.1 - 6.7e-06 26.0 6.6 1.1e-05 25.3 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY52643.1 - 0.00016 21.5 6.6 0.00043 20.1 6.7 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KIY52643.1 - 0.0014 18.4 4.2 0.0034 17.2 4.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KIY52643.1 - 0.0023 18.2 6.3 0.0046 17.2 6.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIY52643.1 - 0.003 17.6 4.1 0.0056 16.7 4.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY_C PF15616.6 KIY52643.1 - 0.012 15.7 1.6 0.062 13.4 1.5 2.0 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_10 PF16685.5 KIY52643.1 - 0.05 13.8 1.7 0.74 10.0 3.7 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-MIZ PF02891.20 KIY52643.1 - 0.068 12.9 7.1 0.57 10.0 8.4 1.9 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-ribbon_3 PF13248.6 KIY52643.1 - 1 8.9 5.7 3.2 7.3 1.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_11 PF17123.5 KIY52643.1 - 3.1 7.6 10.2 1.2 8.9 5.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger Exo_endo_phos PF03372.23 KIY52644.1 - 0.0069 15.9 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dynamitin PF04912.14 KIY52644.1 - 0.0093 15.3 2.3 0.017 14.4 2.3 1.4 1 0 0 1 1 1 1 Dynamitin ICA69 PF04629.14 KIY52644.1 - 0.084 13.2 3.1 0.14 12.5 3.1 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain CDC45 PF02724.14 KIY52645.1 - 0.04 12.2 2.2 0.052 11.9 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_r1_1 PF03979.14 KIY52645.1 - 0.056 13.5 3.3 0.38 10.8 0.9 2.3 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Rubella_Capsid PF05750.11 KIY52645.1 - 0.41 10.2 7.6 0.71 9.4 7.6 1.3 1 0 0 1 1 1 0 Rubella capsid protein zf-CCHC PF00098.23 KIY52649.1 - 4.5e-07 29.7 0.5 4.5e-07 29.7 0.5 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIY52649.1 - 0.0069 16.1 0.6 0.024 14.4 0.6 2.0 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KIY52649.1 - 0.02 14.7 0.4 0.055 13.3 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle PNPase_C PF12111.8 KIY52649.1 - 0.085 12.3 0.8 0.19 11.2 0.8 1.6 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal LIF_OSM PF01291.17 KIY52652.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 LIF / OSM family Symplekin_C PF12295.8 KIY52653.1 - 4.2e-09 36.8 0.0 2.1e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF1400 PF07176.11 KIY52653.1 - 0.016 15.5 0.1 0.38 11.0 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) NUC173 PF08161.12 KIY52653.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.7 1 1 1 2 2 2 0 NUC173 domain Symplekin_C PF12295.8 KIY52654.1 - 3.7e-39 134.8 1.2 4.5e-39 134.5 1.2 1.1 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF4079 PF13301.6 KIY52654.1 - 0.091 12.9 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) HNH_2 PF13391.6 KIY52655.1 - 1.2e-05 25.3 0.1 3.8e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 HNH endonuclease AA_kinase PF00696.28 KIY52656.1 - 1.7e-22 80.2 0.1 2e-22 80.0 0.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family zf-CCHC PF00098.23 KIY52658.1 - 3.3 8.0 6.9 5.2 7.3 6.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Calreticulin PF00262.18 KIY52661.1 - 1.1e-156 521.3 7.5 1.5e-156 520.9 7.5 1.2 1 0 0 1 1 1 1 Calreticulin family Peptidase_U49 PF10463.9 KIY52661.1 - 8 6.2 5.6 1.3 8.7 0.2 2.1 2 0 0 2 2 2 0 Peptidase U49 GTP_EFTU PF00009.27 KIY52663.1 - 1.8e-42 145.1 0.1 2.9e-42 144.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KIY52663.1 - 6.8e-36 123.5 2.7 1.1e-35 122.9 2.7 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KIY52663.1 - 7.2e-24 83.9 0.0 1.4e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KIY52663.1 - 1.2e-21 76.5 0.0 3.5e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIY52663.1 - 3.6e-09 36.9 0.0 7.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KIY52663.1 - 2.1e-06 27.7 0.0 5.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KIY52663.1 - 3.4e-05 23.9 0.1 6.3e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIY52663.1 - 0.003 17.0 0.1 0.017 14.5 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF575 PF04746.12 KIY52663.1 - 0.17 12.1 0.0 7.7 6.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF575) Prefoldin_2 PF01920.20 KIY52664.1 - 1e-16 60.8 6.1 1.2e-16 60.6 6.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mei5 PF10376.9 KIY52664.1 - 0.00051 20.0 2.7 0.0007 19.5 2.7 1.2 1 0 0 1 1 1 1 Double-strand recombination repair protein OmpH PF03938.14 KIY52664.1 - 0.022 15.1 0.5 0.022 15.1 0.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Tropomyosin_1 PF12718.7 KIY52664.1 - 0.022 14.9 1.3 0.022 14.9 1.3 2.0 2 0 0 2 2 2 0 Tropomyosin like LPP PF04728.13 KIY52664.1 - 0.027 14.9 0.2 0.027 14.9 0.2 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Coat_F PF07875.12 KIY52664.1 - 0.028 14.6 2.4 0.46 10.8 0.4 2.3 2 0 0 2 2 2 0 Coat F domain Med30 PF11315.8 KIY52664.1 - 0.057 13.6 4.5 0.097 12.9 4.5 1.4 1 1 0 1 1 1 0 Mediator complex subunit 30 DUF4378 PF14309.6 KIY52664.1 - 0.075 13.4 0.1 0.096 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Fib_alpha PF08702.10 KIY52664.1 - 0.12 12.5 4.4 4.3 7.5 0.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5320 PF17253.2 KIY52664.1 - 0.19 12.8 2.7 0.69 11.0 2.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) NCA2 PF08637.10 KIY52664.1 - 0.27 10.3 3.5 0.33 10.1 0.7 1.9 1 1 1 2 2 2 0 ATP synthase regulation protein NCA2 TolA_bind_tri PF16331.5 KIY52664.1 - 1.2 9.3 10.6 3.6 7.7 0.5 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation Seryl_tRNA_N PF02403.22 KIY52664.1 - 1.3 9.3 8.2 2.2 8.6 6.4 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KIY52664.1 - 4.1 6.7 8.8 21 4.4 8.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) F-box-like PF12937.7 KIY52667.1 - 0.0034 17.2 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like zf-CCHH PF10283.9 KIY52667.1 - 0.09 12.8 1.3 0.26 11.3 1.3 1.7 1 0 0 1 1 1 0 PBZ domain zf-UBR PF02207.20 KIY52668.1 - 1.6e-14 53.8 14.7 1.6e-14 53.8 14.7 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KIY52668.1 - 0.0013 18.5 0.1 0.0055 16.5 0.1 2.1 1 1 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS PBP1_TM PF14812.6 KIY52669.1 - 0.058 13.8 1.2 0.16 12.4 1.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dopey_N PF04118.14 KIY52670.1 - 2.9e-109 364.9 3.1 2.9e-109 364.9 0.2 2.5 3 0 0 3 3 3 1 Dopey, N-terminal DUF2786 PF10979.8 KIY52671.1 - 7.5e-13 48.2 0.6 7.5e-13 48.2 0.6 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2786) Pkinase PF00069.25 KIY52672.1 - 4.4e-47 160.7 0.0 5.3e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52672.1 - 2.6e-25 89.2 0.0 3.1e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY52672.1 - 1.1e-05 24.9 0.0 1.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY52672.1 - 0.0021 18.0 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY52672.1 - 0.052 12.9 0.2 0.074 12.4 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KIY52672.1 - 0.055 13.0 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL YukC PF10140.9 KIY52672.1 - 0.14 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC GMC_oxred_N PF00732.19 KIY52673.1 - 5.6e-48 163.8 0.0 5.5e-40 137.6 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY52673.1 - 2.1e-24 86.7 0.0 5.5e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIY52673.1 - 2.2e-06 27.0 0.0 3.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KIY52673.1 - 5e-05 22.6 0.0 0.062 12.4 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KIY52673.1 - 0.0013 18.0 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KIY52673.1 - 0.0018 17.4 0.8 0.32 10.0 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIY52673.1 - 0.021 14.1 0.2 0.072 12.3 0.2 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY52673.1 - 0.055 13.1 0.2 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY52673.1 - 0.057 12.1 1.0 0.15 10.7 0.4 1.8 2 0 0 2 2 2 0 HI0933-like protein EF-hand_6 PF13405.6 KIY52674.1 - 5e-08 32.3 0.3 0.018 14.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KIY52674.1 - 2.7e-07 30.9 0.9 7.6e-07 29.5 0.9 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KIY52674.1 - 1.3e-05 24.5 1.0 0.00016 21.0 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KIY52674.1 - 7.4e-05 22.0 0.4 0.0016 17.8 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KIY52674.1 - 0.09 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KIY52674.1 - 0.1 12.9 5.8 3.1 8.2 2.3 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PTPA PF03095.15 KIY52675.1 - 4.6e-122 407.2 0.0 5.3e-122 407.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Bromodomain PF00439.25 KIY52676.1 - 3.9e-55 183.9 0.0 8.3e-19 67.4 0.0 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 KIY52676.1 - 4.3e-09 36.3 0.0 8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIY52676.1 - 0.00028 21.1 0.0 0.00059 20.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain WD40 PF00400.32 KIY52677.1 - 5.1e-15 55.6 4.1 8.7e-05 23.2 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY52677.1 - 3.3e-07 30.5 0.0 0.67 10.3 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain zf-MYND PF01753.18 KIY52679.1 - 5e-07 29.7 10.7 7.7e-07 29.1 10.7 1.3 1 0 0 1 1 1 1 MYND finger Ribonuc_L-PSP PF01042.21 KIY52680.1 - 1.7e-40 137.8 0.0 1.9e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.32 KIY52681.1 - 2.1e-05 25.2 11.4 0.0012 19.6 0.1 4.0 6 0 0 6 6 6 2 WD domain, G-beta repeat G-alpha PF00503.20 KIY52683.1 - 3.1e-117 391.7 0.0 3.6e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY52683.1 - 6.1e-14 51.8 0.1 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIY52683.1 - 0.00013 22.1 0.0 0.23 11.7 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIY52683.1 - 0.002 17.6 0.0 0.0066 15.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KIY52683.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KIY52683.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY52683.1 - 0.034 14.5 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 KIY52683.1 - 0.095 12.0 0.2 7.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY52683.1 - 0.12 11.9 0.0 0.84 9.1 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 KIY52683.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain DUF1201 PF06716.11 KIY52685.1 - 0.027 14.5 3.4 0.089 12.8 3.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) DUF2070 PF09843.9 KIY52685.1 - 1.1 7.4 12.1 1.4 7.1 12.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Exo84_C PF16528.5 KIY52686.1 - 8.1e-38 130.3 1.1 1.5e-37 129.5 0.1 2.0 2 1 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KIY52686.1 - 1e-16 60.7 3.3 3.2e-16 59.2 3.3 1.9 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KIY52686.1 - 1.4e-07 31.6 0.4 5.9e-07 29.6 0.4 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 PH_13 PF16652.5 KIY52686.1 - 0.3 10.9 1.5 0.34 10.7 0.2 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain Polyketide_cyc2 PF10604.9 KIY52687.1 - 5.5e-07 30.0 0.4 1.7e-06 28.3 0.4 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIY52687.1 - 0.00071 19.8 0.4 0.0061 16.8 0.4 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KIY52687.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Abhydrolase_3 PF07859.13 KIY52688.1 - 2.4e-64 217.1 0.0 2.9e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY52688.1 - 8.1e-12 44.8 0.1 2.2e-11 43.4 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KIY52688.1 - 4.3e-06 25.8 0.0 5.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KIY52688.1 - 0.0079 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KIY52688.1 - 0.013 15.0 0.0 0.084 12.3 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase PF07224.11 KIY52688.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase DUF2974 PF11187.8 KIY52688.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 KIY52688.1 - 0.77 9.3 6.3 1.5 8.4 0.4 2.9 2 1 0 2 2 2 0 Putative esterase D-ser_dehydrat PF14031.6 KIY52689.1 - 4.6e-26 91.3 0.3 2.3e-25 89.1 0.1 2.3 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KIY52689.1 - 3.2e-15 56.4 0.1 4.9e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ras PF00071.22 KIY52690.1 - 1.4e-53 180.8 0.0 1.7e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY52690.1 - 5.4e-33 113.8 0.0 7.8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY52690.1 - 5.4e-13 48.8 0.0 6.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY52690.1 - 7.5e-06 25.6 0.0 0.00034 20.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIY52690.1 - 6.2e-05 22.5 0.0 7.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY52690.1 - 0.00023 21.2 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KIY52690.1 - 0.0018 17.9 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 KIY52690.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 KaiC DAP3 PF10236.9 KIY52690.1 - 0.0066 15.7 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RsgA_GTPase PF03193.16 KIY52690.1 - 0.01 15.8 0.0 1.7 8.6 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase NACHT PF05729.12 KIY52690.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 KIY52690.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KIY52690.1 - 0.019 15.2 0.0 0.036 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIY52690.1 - 0.042 14.2 0.1 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KIY52690.1 - 0.048 14.2 0.1 0.064 13.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 KIY52690.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.18 KIY52690.1 - 0.064 12.5 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Septin DUF2075 PF09848.9 KIY52690.1 - 0.094 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 KIY52690.1 - 0.1 12.4 0.0 1.8 8.3 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Laminin_II PF06009.12 KIY52691.1 - 0.0015 18.5 3.5 0.0027 17.7 3.5 1.4 1 0 0 1 1 1 1 Laminin Domain II DUF1664 PF07889.12 KIY52691.1 - 0.031 14.3 5.4 0.062 13.3 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ERM PF00769.19 KIY52691.1 - 0.033 14.0 0.2 0.049 13.5 0.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ISG65-75 PF11727.8 KIY52691.1 - 3.1 6.9 6.3 4.9 6.3 6.3 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Spc7 PF08317.11 KIY52691.1 - 4.1 6.2 6.6 5.9 5.7 6.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Stevor PF17410.2 KIY52693.1 - 0.024 14.2 0.3 0.024 14.2 0.3 3.1 2 1 1 3 3 3 0 Subtelomeric Variable Open Reading frame OppC_N PF12911.7 KIY52693.1 - 0.032 14.2 0.4 0.073 13.1 0.4 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PMP1_2 PF08114.11 KIY52693.1 - 0.082 12.7 1.6 0.16 11.8 1.6 1.5 1 0 0 1 1 1 0 ATPase proteolipid family SKG6 PF08693.10 KIY52693.1 - 2.6 7.5 10.5 0.06 12.8 2.0 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain EamA PF00892.20 KIY52694.1 - 2.8e-05 24.3 46.4 7.6e-05 22.9 16.6 3.8 3 1 0 3 3 3 2 EamA-like transporter family Ribosomal_L36 PF00444.18 KIY52695.1 - 3.1e-18 65.7 7.7 4.3e-18 65.2 7.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 DHFR_1 PF00186.19 KIY52696.1 - 9.9e-28 96.9 0.0 1.6e-27 96.2 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase ZZ PF00569.17 KIY52696.1 - 0.056 13.3 0.8 0.095 12.5 0.3 1.5 2 0 0 2 2 2 0 Zinc finger, ZZ type ICE2 PF08426.10 KIY52697.1 - 2.1e-28 99.6 24.1 1.4e-15 57.3 8.4 3.0 1 1 1 2 2 2 2 ICE2 Serinc PF03348.15 KIY52697.1 - 0.019 13.9 3.8 0.026 13.5 3.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CPSase_L_D2 PF02786.17 KIY52698.1 - 6.3e-68 228.4 0.0 1.3e-67 227.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIY52698.1 - 1.2e-38 132.0 0.1 8.2e-38 129.3 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIY52698.1 - 9.6e-32 109.3 0.0 8.2e-23 80.6 0.0 2.5 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIY52698.1 - 3.7e-14 52.3 1.7 7.8e-14 51.3 1.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KIY52698.1 - 1.1e-08 34.8 0.0 2.5e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KIY52698.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain RnfC_N PF13375.6 KIY52698.1 - 0.14 12.1 2.1 4.7 7.2 0.3 3.0 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain Dus PF01207.17 KIY52699.1 - 3.2e-52 177.5 0.0 1.1e-51 175.8 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ACP_PD PF04336.12 KIY52700.1 - 0.12 12.8 0.3 0.21 12.1 0.3 1.3 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase Galactosyl_T PF01762.21 KIY52701.1 - 1.1e-08 35.1 0.0 0.00054 19.8 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase GST_C_2 PF13410.6 KIY52702.1 - 0.00011 22.2 0.1 0.00038 20.4 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY52702.1 - 0.002 18.5 0.1 0.0044 17.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY52702.1 - 0.0028 17.8 0.1 0.016 15.4 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY52702.1 - 0.0044 17.3 0.1 0.073 13.4 0.0 2.6 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain Calponin PF00402.18 KIY52702.1 - 0.33 10.6 1.1 0.61 9.8 1.1 1.3 1 0 0 1 1 1 0 Calponin family repeat SGS PF05002.15 KIY52703.1 - 3.1e-33 113.7 2.2 4.4e-33 113.2 2.2 1.2 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KIY52703.1 - 1.5e-11 45.2 0.0 2.6e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 CS domain UPF0139 PF03669.13 KIY52704.1 - 4.2e-06 26.5 0.0 9.8e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0139) Rad21_Rec8_N PF04825.13 KIY52705.1 - 5.1e-20 71.7 0.0 1e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KIY52705.1 - 0.00029 20.1 0.0 0.0008 18.6 0.0 1.7 1 1 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF1195 PF06708.11 KIY52705.1 - 0.16 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) NUDIX PF00293.28 KIY52706.1 - 4.7e-22 78.4 0.0 6.3e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S17_N PF16205.5 KIY52707.1 - 9.1e-31 106.1 0.3 1.8e-30 105.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KIY52707.1 - 2.4e-28 98.0 2.7 4.4e-28 97.2 2.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Metallophos PF00149.28 KIY52708.1 - 4.1e-38 131.9 0.0 1.3e-37 130.3 0.0 1.7 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY52708.1 - 2.6e-14 53.4 0.1 4.7e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DCP2 PF05026.13 KIY52709.1 - 2.6e-29 101.3 0.3 1.9e-27 95.4 0.3 2.2 2 0 0 2 2 2 2 Dcp2, box A domain NUDIX PF00293.28 KIY52709.1 - 2.3e-15 56.8 0.0 4.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pribosyltran_N PF13793.6 KIY52710.1 - 1.2e-44 150.9 1.1 5e-43 145.7 0.2 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KIY52710.1 - 1.7e-36 126.0 0.8 3.2e-30 105.5 0.3 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KIY52710.1 - 3.2e-15 56.0 1.6 5.3e-15 55.3 0.1 1.9 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIY52710.1 - 0.0053 16.2 0.1 0.0093 15.4 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pkinase PF00069.25 KIY52711.1 - 1.5e-51 175.3 0.0 2.2e-50 171.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52711.1 - 1.3e-24 87.0 0.0 2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBP_sp32 PF07222.12 KIY52711.1 - 0.029 13.8 0.1 0.078 12.4 0.1 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DivIVA PF05103.13 KIY52711.1 - 5.6 7.1 7.1 9.2 6.4 7.1 1.2 1 0 0 1 1 1 0 DivIVA protein zf-CHCC PF10276.9 KIY52712.1 - 3.2e-12 46.3 0.4 4.7e-12 45.7 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger domain TPR_16 PF13432.6 KIY52714.1 - 1.4e-41 140.9 31.8 1.1e-11 45.2 1.5 11.6 9 3 3 12 12 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIY52714.1 - 1.2e-31 106.2 40.4 0.00023 21.1 0.2 17.3 19 0 0 19 19 19 6 Tetratricopeptide repeat TPR_1 PF00515.28 KIY52714.1 - 1.2e-30 104.0 27.8 3e-05 23.6 0.0 13.6 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 KIY52714.1 - 2.6e-29 101.5 40.8 3.5e-06 27.4 1.9 11.8 10 2 3 14 14 13 8 Tetratricopeptide repeat TPR_14 PF13428.6 KIY52714.1 - 2.1e-23 81.0 47.6 8.4e-06 26.2 0.1 17.0 14 4 6 20 20 17 4 Tetratricopeptide repeat TPR_17 PF13431.6 KIY52714.1 - 1.7e-17 62.4 26.5 0.035 14.5 0.1 14.0 16 0 0 16 16 14 4 Tetratricopeptide repeat TPR_6 PF13174.6 KIY52714.1 - 6.3e-17 61.0 22.0 0.0067 17.0 0.0 12.1 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY52714.1 - 1.1e-16 59.6 25.8 0.014 15.5 0.0 15.0 16 0 0 16 16 15 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY52714.1 - 1.2e-15 57.5 17.1 2.4e-07 30.9 0.1 7.2 6 2 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KIY52714.1 - 1.2e-14 54.2 26.0 7.5e-05 22.8 0.5 10.6 10 1 0 11 11 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY52714.1 - 5.5e-12 45.8 44.0 4.9e-05 23.5 0.3 10.9 10 3 3 13 13 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 KIY52714.1 - 4.6e-10 39.0 29.1 0.0058 16.3 0.3 11.7 10 2 3 13 13 13 4 TPR repeat TPR_7 PF13176.6 KIY52714.1 - 2.3e-09 36.6 15.2 3.3 7.9 0.0 10.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_20 PF14561.6 KIY52714.1 - 2.1e-05 24.8 10.8 0.18 12.2 0.1 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.10 KIY52714.1 - 4.5e-05 22.6 4.0 0.04 12.9 0.5 4.3 3 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) PknG_TPR PF16918.5 KIY52714.1 - 0.001 17.9 11.9 0.03 13.1 0.1 5.2 5 1 1 6 6 6 1 Protein kinase G tetratricopeptide repeat ANAPC5 PF12862.7 KIY52714.1 - 0.0032 17.5 1.8 0.74 9.9 0.0 4.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 Fis1_TPR_C PF14853.6 KIY52714.1 - 0.0054 16.8 4.3 0.45 10.6 0.1 5.2 7 0 0 7 7 5 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 KIY52714.1 - 0.0082 15.1 4.9 1 8.2 0.0 3.8 4 0 0 4 4 4 1 NMDA receptor-regulated protein 1 DUF2225 PF09986.9 KIY52714.1 - 0.0083 15.9 0.4 0.66 9.7 0.0 3.8 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) Wzy_C_2 PF11846.8 KIY52714.1 - 0.031 14.2 10.8 0.032 14.2 0.0 3.9 5 0 0 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal TPR_22 PF18833.1 KIY52714.1 - 0.15 12.2 0.0 2 8.6 0.0 2.9 4 0 0 4 4 2 0 Tetratricopeptide repeat FAT PF02259.23 KIY52714.1 - 0.16 11.1 1.6 0.91 8.7 0.0 3.0 3 0 0 3 3 3 0 FAT domain TPR_10 PF13374.6 KIY52714.1 - 0.2 11.6 17.7 13 5.8 0.9 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.17 KIY52714.1 - 0.39 11.1 13.7 0.84 10.1 0.2 5.3 5 1 1 6 6 6 0 Bacterial transcriptional activator domain SNAP PF14938.6 KIY52714.1 - 0.43 10.0 11.3 9.2 5.6 0.0 5.3 5 1 0 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 KIY52714.1 - 2 9.3 27.7 7.2 7.6 0.0 7.6 7 0 0 7 7 5 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.21 KIY52715.1 - 1.1e-62 211.3 0.4 1.6e-62 210.8 0.4 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIY52715.1 - 1.1e-41 143.0 0.4 2.2e-41 142.1 0.4 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KIY52715.1 - 2.3e-24 85.8 0.0 6e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KIY52715.1 - 0.0019 18.6 0.1 0.0037 17.6 0.1 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KIY52715.1 - 0.034 14.2 0.0 9.9 6.3 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain DASH_Ask1 PF08655.10 KIY52716.1 - 2.3e-24 85.1 0.4 4.9e-24 84.0 0.4 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 Trypan_PARP PF05887.11 KIY52716.1 - 4.7 7.2 17.8 0.081 12.9 9.8 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) INCENP_ARK-bind PF03941.15 KIY52717.1 - 1.5e-18 66.5 0.2 2.2e-18 66.0 0.2 1.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region MPC PF03650.13 KIY52718.1 - 1.6e-33 115.2 0.7 5.4e-32 110.2 0.7 2.0 1 1 0 1 1 1 1 Mitochondrial pyruvate carriers DUF3292 PF11696.8 KIY52720.1 - 0.00086 17.8 4.1 0.058 11.8 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) GRAM PF02893.20 KIY52720.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Mg_trans_NIPA PF05653.14 KIY52721.1 - 1e-20 74.0 13.6 3.9e-10 39.3 6.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA AAA_2 PF07724.14 KIY52722.1 - 6.5e-52 176.1 0.0 3.9e-48 163.8 0.0 3.3 4 0 0 4 4 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIY52722.1 - 2.3e-32 111.0 2.7 2.3e-32 111.0 2.7 3.4 2 1 1 3 3 3 1 AAA lid domain ClpB_D2-small PF10431.9 KIY52722.1 - 2.5e-26 91.6 0.2 8.5e-26 89.8 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KIY52722.1 - 2.6e-26 92.6 0.0 7.9e-13 49.0 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 KIY52722.1 - 1.3e-16 60.4 4.0 8.8e-12 45.0 0.3 4.0 2 1 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 KIY52722.1 - 2.7e-14 53.9 0.6 8.9e-06 26.2 0.0 4.7 4 1 1 5 5 3 2 AAA ATPase domain AAA_5 PF07728.14 KIY52722.1 - 1.1e-12 48.1 0.1 4.7e-06 26.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KIY52722.1 - 1.2e-09 38.1 0.0 1.8e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KIY52722.1 - 9.1e-08 32.5 0.1 0.041 14.2 0.0 4.3 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIY52722.1 - 3.1e-07 30.3 0.0 0.0036 17.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KIY52722.1 - 5.9e-06 26.1 0.0 0.022 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KIY52722.1 - 7.8e-06 25.4 0.0 0.0067 15.8 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KIY52722.1 - 1.8e-05 24.2 1.7 0.02 14.1 0.1 3.2 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_18 PF13238.6 KIY52722.1 - 2.7e-05 24.7 0.8 0.11 13.1 0.0 3.4 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KIY52722.1 - 4.7e-05 23.7 0.1 0.45 10.9 0.0 3.1 3 0 0 3 3 2 2 RNA helicase TniB PF05621.11 KIY52722.1 - 9.3e-05 21.9 0.0 0.066 12.6 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein RuvB_N PF05496.12 KIY52722.1 - 0.00011 21.9 0.8 0.46 10.2 0.0 3.8 5 0 0 5 5 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KIY52722.1 - 0.00014 21.5 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 KIY52722.1 - 0.00024 21.3 0.0 0.39 10.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIY52722.1 - 0.00031 21.0 1.1 1.4 9.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KIY52722.1 - 0.00063 19.7 0.0 0.62 10.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 KIY52722.1 - 0.00066 19.9 0.0 0.63 10.3 0.0 3.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KIY52722.1 - 0.00069 18.9 0.0 0.069 12.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Laminin_II PF06009.12 KIY52722.1 - 0.0013 18.7 1.5 0.0029 17.6 1.5 1.6 1 0 0 1 1 1 1 Laminin Domain II DNA_pol3_delta2 PF13177.6 KIY52722.1 - 0.0018 18.1 1.1 0.72 9.6 0.0 3.7 4 1 0 4 4 3 1 DNA polymerase III, delta subunit ABC_tran PF00005.27 KIY52722.1 - 0.0023 18.5 0.2 0.97 9.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter TsaE PF02367.17 KIY52722.1 - 0.003 17.6 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KIY52722.1 - 0.0048 16.4 0.0 0.54 9.7 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DUF5368 PF17336.2 KIY52722.1 - 0.0065 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5368) AAA_30 PF13604.6 KIY52722.1 - 0.0069 16.1 0.5 4.8 6.9 0.0 3.2 3 1 0 3 3 2 0 AAA domain AAA_3 PF07726.11 KIY52722.1 - 0.008 16.0 0.0 42 4.0 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KIY52722.1 - 0.0094 16.0 0.0 0.84 9.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KIY52722.1 - 0.011 15.7 0.0 4.8 7.0 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase ResIII PF04851.15 KIY52722.1 - 0.011 15.8 0.0 0.74 9.8 0.0 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Torsin PF06309.11 KIY52722.1 - 0.021 14.9 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Torsin AAA_25 PF13481.6 KIY52722.1 - 0.026 14.1 2.8 11 5.5 0.1 3.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KIY52722.1 - 0.033 14.5 0.0 8.1 6.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain Sigma54_activ_2 PF14532.6 KIY52722.1 - 0.043 13.9 0.0 9.9 6.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KIY52722.1 - 0.045 13.7 3.8 5.6 6.8 0.1 4.2 4 1 0 5 5 3 0 ATPase domain predominantly from Archaea CbiA PF01656.23 KIY52722.1 - 0.047 13.7 0.1 21 5.2 0.0 3.8 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KIY52722.1 - 0.057 13.3 0.0 5.7 6.8 0.0 3.6 4 0 0 4 4 3 0 NTPase APS_kinase PF01583.20 KIY52722.1 - 0.078 12.9 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_29 PF13555.6 KIY52722.1 - 0.2 11.4 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain SOAR PF16533.5 KIY52722.1 - 0.32 11.0 3.6 1 9.4 3.6 1.9 1 0 0 1 1 1 0 STIM1 Orai1-activating region Spc7 PF08317.11 KIY52722.1 - 0.53 9.1 7.1 1 8.2 7.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein YlqD PF11068.8 KIY52722.1 - 0.69 10.3 4.5 2.2 8.7 4.5 1.8 1 0 0 1 1 1 0 YlqD protein Atg14 PF10186.9 KIY52722.1 - 0.71 8.9 4.9 1.1 8.3 4.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 5_nucleotid PF05761.14 KIY52722.1 - 2.3 7.0 3.4 3.9 6.3 3.4 1.3 1 0 0 1 1 1 0 5' nucleotidase family DUF4337 PF14235.6 KIY52722.1 - 5.8 7.0 6.8 13 5.9 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AAA_23 PF13476.6 KIY52722.1 - 6.2 7.3 17.6 5.5 7.4 0.0 3.9 3 1 0 3 3 2 0 AAA domain ELO PF01151.18 KIY52723.1 - 1.2e-57 195.3 19.4 1.6e-57 194.9 19.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family RasGAP PF00616.19 KIY52724.1 - 1.7e-25 90.0 0.0 9.6e-19 67.9 0.0 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KIY52724.1 - 2.2e-07 31.1 0.0 3.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain 2-Hacid_dh_C PF02826.19 KIY52725.1 - 4.5e-43 146.7 0.0 1.8e-42 144.7 0.0 1.8 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY52725.1 - 7.8e-15 54.7 0.0 9.5e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY52725.1 - 0.00014 22.0 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F-box-like PF12937.7 KIY52727.1 - 7.3e-09 35.4 0.1 4.5e-08 32.9 0.1 2.5 1 1 0 1 1 1 1 F-box-like DENN PF02141.21 KIY52728.1 - 2e-20 73.5 0.0 3.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain Jnk-SapK_ap_N PF09744.9 KIY52728.1 - 0.076 13.2 7.3 0.18 12.0 7.3 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 YabA PF06156.13 KIY52728.1 - 0.095 13.3 4.4 7.7 7.2 0.6 2.5 2 0 0 2 2 2 0 Initiation control protein YabA FAM184 PF15665.5 KIY52728.1 - 0.11 12.3 9.1 0.22 11.3 9.1 1.5 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B GAS PF13851.6 KIY52728.1 - 0.3 10.4 10.0 0.6 9.4 10.0 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding EspB_PE PF18625.1 KIY52728.1 - 0.47 10.9 3.0 0.52 10.8 0.4 2.4 1 1 1 2 2 2 0 ESX-1 secreted protein B PE domain APG6_N PF17675.1 KIY52728.1 - 0.68 10.5 10.7 1.7 9.2 10.7 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Filament PF00038.21 KIY52728.1 - 0.72 9.4 14.0 1.8 8.1 13.2 1.9 1 1 1 2 2 2 0 Intermediate filament protein SOGA PF11365.8 KIY52728.1 - 4 8.6 10.2 0.55 11.4 3.2 2.6 1 1 1 2 2 2 0 Protein SOGA ABC_tran_CTD PF16326.5 KIY52728.1 - 4.7 7.5 15.4 23 5.3 13.3 3.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain Atg14 PF10186.9 KIY52728.1 - 6.7 5.7 8.3 16 4.4 8.3 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 VPS13_mid_rpt PF16910.5 KIY52729.1 - 1.9e-97 325.3 12.8 2.4e-92 308.7 1.1 5.3 4 1 1 5 5 5 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KIY52729.1 - 4.4e-76 255.8 2.0 1.4e-71 241.0 0.1 3.7 3 0 0 3 3 3 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KIY52729.1 - 1.2e-70 237.0 4.9 3.4e-66 222.4 0.1 3.2 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KIY52729.1 - 2e-60 204.4 0.0 1.2e-57 195.3 0.0 3.2 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 KIY52729.1 - 2e-26 92.4 0.0 9.5e-26 90.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KIY52729.1 - 4e-10 39.9 0.3 9.2e-09 35.5 0.1 3.3 4 0 0 4 4 4 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 KIY52729.1 - 0.0013 17.6 0.4 0.3 9.9 0.0 3.1 3 0 0 3 3 3 2 Golgi-body localisation protein domain Cerato-platanin PF07249.12 KIY52730.1 - 4.2e-34 117.2 1.7 5.2e-34 116.9 1.7 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 KIY52730.1 - 0.00015 21.6 0.1 0.00017 21.4 0.1 1.2 1 0 0 1 1 1 1 Barwin family HA2 PF04408.23 KIY52731.1 - 2.4e-15 56.7 0.0 6.8e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY52731.1 - 6.7e-15 55.4 0.0 4.8e-14 52.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY52731.1 - 2.1e-07 30.9 0.3 4.1e-07 29.9 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KIY52731.1 - 7.1e-05 23.2 0.1 0.00018 21.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain dsrm PF00035.26 KIY52731.1 - 0.00067 20.3 0.0 0.0054 17.4 0.0 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 KIY52731.1 - 0.028 14.8 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.15 KIY52731.1 - 0.031 14.3 0.1 0.095 12.7 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIY52731.1 - 0.09 12.5 0.3 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIY52731.1 - 0.092 12.3 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIY52731.1 - 0.096 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 KIY52731.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Adaptin_N PF01602.20 KIY52732.1 - 1.8e-126 422.8 2.5 2.2e-126 422.5 2.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KIY52732.1 - 2.8e-39 133.8 0.0 6.2e-39 132.7 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KIY52732.1 - 8.7e-09 35.7 0.0 7.1e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KIY52732.1 - 8.5e-06 25.9 0.1 0.00051 20.1 0.0 2.7 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RGI1 PF10843.8 KIY52732.1 - 0.044 13.4 0.6 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Respiratory growth induced protein 1 HEAT PF02985.22 KIY52732.1 - 0.083 13.2 0.5 2.5 8.6 0.0 3.6 5 0 0 5 5 5 0 HEAT repeat Pex24p PF06398.11 KIY52733.1 - 5.9e-09 35.4 0.2 7.2e-09 35.1 0.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin WD40 PF00400.32 KIY52734.1 - 0.00063 20.5 8.8 0.27 12.2 0.0 4.2 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY52734.1 - 0.083 13.2 0.0 3 8.2 0.0 2.9 2 2 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TMEM135_C_rich PF15982.5 KIY52735.1 - 2.5e-05 24.9 0.1 6.4e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 IBV_3C PF03620.13 KIY52735.1 - 0.35 11.4 1.3 13 6.3 0.2 3.0 3 0 0 3 3 3 0 IBV 3C protein PhnA_Zn_Ribbon PF08274.12 KIY52736.1 - 1.3 9.0 4.5 19 5.3 0.7 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon AGTRAP PF06396.11 KIY52737.1 - 1.1e-06 28.5 0.3 3e-06 27.1 0.3 1.7 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) UQ_con PF00179.26 KIY52738.1 - 3.5e-40 136.9 0.1 4.4e-40 136.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIY52738.1 - 0.058 13.3 0.2 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 UEV domain Transthyretin PF00576.21 KIY52739.1 - 2.9e-36 124.5 0.0 3.3e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 KIY52739.1 - 0.027 14.8 0.0 0.049 13.9 0.0 1.4 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Aldose_epim PF01263.20 KIY52740.1 - 9.4e-30 103.9 0.2 1.1e-29 103.8 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4432 PF14486.6 KIY52740.1 - 0.045 12.5 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) DUF5001 PF16392.5 KIY52740.1 - 0.047 13.6 0.3 0.63 10.0 0.1 2.3 1 1 1 2 2 2 0 Ig-like domain HEAT PF02985.22 KIY52741.1 - 7.3e-39 128.5 20.6 0.0052 16.9 0.0 13.6 15 0 0 15 15 15 9 HEAT repeat HEAT_2 PF13646.6 KIY52741.1 - 3.1e-36 123.6 7.8 2.5e-11 43.8 0.0 7.0 2 2 3 6 6 6 6 HEAT repeats Cnd1 PF12717.7 KIY52741.1 - 1.6e-11 44.5 1.1 0.0006 19.9 0.0 4.9 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KIY52741.1 - 2.3e-10 41.0 0.1 0.27 11.9 0.0 7.4 3 3 7 10 10 10 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KIY52741.1 - 9.6e-10 37.6 0.1 2.2e-05 23.3 0.2 3.0 1 1 1 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 KIY52741.1 - 1.4e-07 31.8 12.4 1.9 9.1 0.1 8.4 7 3 2 9 9 9 3 HEAT-like repeat Arm PF00514.23 KIY52741.1 - 1.1e-05 25.3 1.8 16 5.7 0.0 5.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KIY52741.1 - 0.0013 18.3 0.0 0.46 10.0 0.0 3.7 1 1 3 4 4 4 1 CLASP N terminal API5 PF05918.11 KIY52741.1 - 0.016 14.0 0.2 3.3 6.4 0.1 3.8 4 0 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) IFRD PF05004.13 KIY52741.1 - 0.081 12.0 0.2 1.2 8.2 0.1 3.0 2 2 0 2 2 2 0 Interferon-related developmental regulator (IFRD) DRIM PF07539.12 KIY52741.1 - 0.11 10.8 0.7 0.46 8.7 0.8 2.0 1 1 0 1 1 1 0 Down-regulated in metastasis DUF4870 PF09685.10 KIY52744.1 - 0.1 12.7 1.9 0.15 12.2 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) Ribosomal_S24e PF01282.19 KIY52745.1 - 1.1e-34 118.2 0.0 2.1e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e Actin PF00022.19 KIY52746.1 - 2.3e-129 431.6 0.0 1.2e-128 429.3 0.0 1.8 1 1 0 1 1 1 1 Actin DNA_primase_S PF01896.19 KIY52746.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA primase small subunit GPI2 PF06432.11 KIY52749.1 - 2e-89 299.8 10.1 2.2e-89 299.6 10.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2160 PF09928.9 KIY52749.1 - 0.037 14.4 0.1 0.037 14.4 0.1 2.8 2 1 1 3 3 3 0 Predicted small integral membrane protein (DUF2160) DUF2339 PF10101.9 KIY52749.1 - 0.49 8.9 24.2 2.2 6.7 24.2 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) Cep57_MT_bd PF06657.13 KIY52750.1 - 0.069 13.6 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 ANAPC4 PF12896.7 KIY52751.1 - 2.3e-28 99.1 0.4 4.1e-28 98.3 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KIY52751.1 - 8.1e-05 22.8 0.1 0.00017 21.8 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain HPS3_C PF14763.6 KIY52751.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal TauD PF02668.16 KIY52752.1 - 2e-47 162.3 0.1 2.6e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aa_trans PF01490.18 KIY52753.1 - 2.8e-29 102.0 37.3 3.3e-29 101.8 37.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DEAD PF00270.29 KIY52754.1 - 7.6e-47 159.3 0.0 1.8e-46 158.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY52754.1 - 1.2e-31 109.3 0.0 2.9e-29 101.6 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 KIY52754.1 - 0.17 12.0 0.7 1.1 9.5 0.0 2.6 2 1 1 3 3 3 0 Helicase C-terminal domain Caskin-Pro-rich PF16907.5 KIY52754.1 - 2.2 8.9 10.6 0.16 12.5 2.8 2.8 2 0 0 2 2 2 0 Proline rich region of Caskin proteins RasGEF PF00617.19 KIY52755.1 - 5.1e-33 114.7 0.0 7.8e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY52755.1 - 6.1e-11 42.5 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 KIY52755.1 - 0.015 14.9 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.6 KIY52755.1 - 0.033 14.6 0.0 0.095 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 KIY52755.1 - 0.084 12.1 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Septin DUF4537 PF15057.6 KIY52756.1 - 0.0031 17.5 0.2 0.052 13.6 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4537) SurE PF01975.17 KIY52757.1 - 6e-44 150.2 0.0 8.3e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Ribosomal_L15e PF00827.17 KIY52759.1 - 9.3e-91 302.7 11.3 1.1e-90 302.5 11.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Histone PF00125.24 KIY52760.1 - 2.4e-22 79.7 0.0 2.9e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ANAPC5 PF12862.7 KIY52760.1 - 0.022 14.8 0.1 0.031 14.3 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Jagunal PF07086.12 KIY52761.1 - 0.25 11.4 1.5 0.35 10.9 1.5 1.3 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis UPF0160 PF03690.13 KIY52762.1 - 4.1e-134 447.2 0.0 4.6e-134 447.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SpoIIIAH PF12685.7 KIY52763.1 - 0.0055 16.5 5.0 0.0059 16.5 5.0 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein Mucin PF01456.17 KIY52763.1 - 0.0099 15.9 18.1 0.016 15.2 18.1 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF4614 PF15391.6 KIY52763.1 - 0.01 15.8 13.7 0.012 15.6 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1180 PF06679.12 KIY52763.1 - 0.061 13.7 7.1 0.074 13.5 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NPR3 PF03666.13 KIY52763.1 - 0.23 10.2 2.2 0.25 10.1 2.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 KIY52763.1 - 0.25 10.1 12.5 0.27 10.0 12.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 KIY52763.1 - 0.37 10.6 9.3 0.37 10.7 9.3 1.0 1 0 0 1 1 1 0 SPX domain DUF1980 PF09323.10 KIY52763.1 - 0.4 10.6 2.4 0.52 10.2 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SOG2 PF10428.9 KIY52763.1 - 4.5 6.4 18.2 4.8 6.3 18.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein MID_MedPIWI PF18296.1 KIY52763.1 - 7.2 6.3 10.4 9.3 6.0 10.4 1.1 1 0 0 1 1 1 0 MID domain of medPIWI DUF1635 PF07795.11 KIY52763.1 - 8.9 6.1 9.6 11 5.8 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Glyco_hydro_92 PF07971.12 KIY52765.1 - 4.7e-130 434.6 0.9 5.7e-130 434.3 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIY52765.1 - 5.9e-54 183.5 0.5 9.6e-54 182.8 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DPBB_1 PF03330.18 KIY52766.1 - 1.7e-06 28.2 0.0 2.2e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase SUA5 PF03481.13 KIY52766.1 - 0.095 13.3 0.0 8.3 7.0 0.0 2.0 1 1 1 2 2 2 0 Putative GTP-binding controlling metal-binding SAD_SRA PF02182.17 KIY52767.1 - 9.4e-38 129.4 0.1 1.7e-37 128.5 0.1 1.4 1 0 0 1 1 1 1 SAD/SRA domain Protoglobin PF11563.8 KIY52768.1 - 2.3e-40 138.1 0.0 2.6e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Protoglobin DPBB_1 PF03330.18 KIY52769.1 - 2.2e-10 40.7 0.8 4.2e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Lytic transglycolase Barwin PF00967.17 KIY52769.1 - 0.24 11.3 2.8 0.18 11.7 0.2 2.1 2 0 0 2 2 2 0 Barwin family Methyltransf_2 PF00891.18 KIY52770.1 - 1.6e-17 63.5 0.0 1.8e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 KIY52770.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain HTH_IclR PF09339.10 KIY52770.1 - 0.017 14.9 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 KIY52770.1 - 0.019 14.8 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 KIY52770.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Mpp10 PF04006.12 KIY52772.1 - 8e-112 374.7 35.1 1.1e-111 374.2 35.1 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF1542 PF07564.11 KIY52772.1 - 0.11 12.6 1.2 0.58 10.3 1.2 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) CENP-H PF05837.12 KIY52772.1 - 3 8.3 7.4 12 6.3 0.8 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) V-SNARE_C PF12352.8 KIY52773.1 - 0.023 15.0 3.3 1.7 9.0 0.2 3.0 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Adeno_52K PF03052.15 KIY52773.1 - 0.55 9.6 5.3 0.8 9.1 3.8 2.1 2 1 0 2 2 2 0 Adenoviral protein L1 52/55-kDa Methyltransf_16 PF10294.9 KIY52777.1 - 1.9e-15 57.0 0.0 3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KIY52777.1 - 0.05 14.3 0.1 0.16 12.7 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIY52777.1 - 0.058 14.1 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Adeno_PIX PF03955.14 KIY52777.1 - 0.07 13.3 0.4 0.17 12.0 0.4 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) V-ATPase_G PF03179.15 KIY52780.1 - 1.3e-33 115.6 15.6 1.5e-33 115.4 15.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KIY52780.1 - 0.8 9.8 19.0 0.18 11.9 13.2 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) SAM_1 PF00536.30 KIY52781.1 - 1.1e-15 57.8 0.0 2.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KIY52781.1 - 1.1e-12 47.8 0.0 2.1e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SlyX PF04102.12 KIY52781.1 - 0.0099 16.5 0.6 0.028 15.0 0.6 1.8 1 0 0 1 1 1 1 SlyX RA PF00788.23 KIY52781.1 - 0.035 14.7 0.0 0.079 13.6 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain KxDL PF10241.9 KIY52781.1 - 0.1 12.9 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein Peptidase_M14 PF00246.24 KIY52782.1 - 2e-62 211.7 0.0 1.5e-60 205.5 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase Myb_DNA-bind_2 PF08914.11 KIY52785.1 - 1.1e-08 35.1 1.1 5.6e-08 32.8 1.1 2.2 1 1 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 KIY52785.1 - 2.4e-06 27.8 0.0 5.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY52785.1 - 0.0014 19.0 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain FAD_binding_3 PF01494.19 KIY52786.1 - 3.9e-69 233.6 0.0 5.2e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KIY52786.1 - 5.9e-31 107.7 0.0 1.1e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KIY52786.1 - 0.00098 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY52786.1 - 0.0012 19.0 0.0 0.004 17.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIY52786.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.6 KIY52786.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain MR_MLE_C PF13378.6 KIY52787.1 - 1e-41 142.9 0.0 1.4e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIY52787.1 - 3.1e-08 33.8 0.0 5.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TFIIB_C_1 PF18542.1 KIY52788.1 - 0.1 12.6 0.1 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 zf-C3HC4 PF00097.25 KIY52789.1 - 9.3e-10 38.2 7.6 3.1e-09 36.6 7.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY52789.1 - 4.7e-08 32.8 5.6 4.7e-08 32.8 5.6 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 KIY52789.1 - 1.4e-07 31.1 29.5 0.0051 16.6 4.2 3.7 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH PF00642.24 KIY52789.1 - 3.7e-07 29.9 26.5 0.00011 22.0 3.3 3.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 KIY52789.1 - 4e-07 29.9 7.9 1.2e-06 28.4 7.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY52789.1 - 5.2e-07 29.6 3.2 5.2e-07 29.6 3.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY52789.1 - 6.1e-07 29.7 8.2 6.1e-07 29.7 8.2 2.9 3 0 0 3 3 3 1 Ring finger domain Torus PF16131.5 KIY52789.1 - 6.8e-07 30.0 12.6 6.8e-05 23.5 0.7 3.3 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 KIY52789.1 - 2.3e-06 27.5 7.1 2.3e-06 27.5 7.1 4.4 4 0 0 4 4 4 2 Zinc finger domain zf-C3HC4_2 PF13923.6 KIY52789.1 - 1.3e-05 25.0 1.6 1.3e-05 25.0 1.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 KIY52789.1 - 2.8e-05 24.4 28.3 0.015 15.7 3.1 4.0 3 1 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 KIY52789.1 - 8.5e-05 22.8 3.7 8.5e-05 22.8 3.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KIY52789.1 - 0.0041 16.9 7.6 0.0041 16.9 7.6 3.1 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIY52789.1 - 0.016 15.3 10.1 0.15 12.2 10.3 2.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 KIY52789.1 - 0.36 10.1 1.3 0.48 9.7 1.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_6 PF14835.6 KIY52789.1 - 0.76 9.7 8.9 6.2 6.8 8.8 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 KIY52789.1 - 4.8 6.9 11.7 11 5.8 7.7 2.9 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Acetyltransf_9 PF13527.7 KIY52790.1 - 0.00013 22.1 0.0 0.1 12.7 0.0 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIY52790.1 - 0.0024 18.0 0.7 2.1 8.5 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY52790.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY52790.1 - 0.035 14.3 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pyr_redox_3 PF13738.6 KIY52791.1 - 2.3e-21 76.3 0.0 5.9e-21 75.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIY52791.1 - 1.3e-20 73.4 1.7 3.5e-19 68.6 0.4 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIY52791.1 - 3.6e-14 52.7 0.3 8.7e-11 41.6 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY52791.1 - 1.4e-09 37.6 0.0 1.1e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIY52791.1 - 1.9e-07 31.6 0.7 0.0028 18.2 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIY52791.1 - 1.6e-06 27.6 0.1 0.0038 16.6 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KIY52791.1 - 3.1e-06 27.3 0.0 5.6e-05 23.3 0.0 3.0 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KIY52791.1 - 1.3e-05 25.2 0.1 0.016 15.1 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIY52791.1 - 1.7e-05 24.3 0.1 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIY52791.1 - 0.00025 19.9 0.1 0.02 13.6 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein IlvN PF07991.12 KIY52791.1 - 0.0012 18.5 0.2 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KIY52791.1 - 0.0021 18.1 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KIY52791.1 - 0.0029 16.9 0.1 0.35 10.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIY52791.1 - 0.0034 17.0 0.9 0.028 14.0 0.3 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KIY52791.1 - 0.0039 16.3 1.0 1.7 7.7 0.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KIY52791.1 - 0.0047 16.0 1.0 0.0096 15.0 0.0 1.9 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KIY52791.1 - 0.019 14.3 1.2 1.9 7.7 1.2 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase Mur_ligase PF01225.25 KIY52791.1 - 0.023 15.0 0.0 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Mur ligase family, catalytic domain TrkA_N PF02254.18 KIY52791.1 - 0.047 14.0 0.4 0.46 10.8 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain Malic_M PF03949.15 KIY52791.1 - 0.059 12.6 0.1 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 KIY52791.1 - 0.093 12.0 0.1 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KIY52791.1 - 0.11 11.5 4.3 0.058 12.5 0.7 2.0 2 0 0 2 2 2 0 FAD binding domain PAS_3 PF08447.12 KIY52791.1 - 0.14 12.5 0.1 0.74 10.1 0.1 2.2 2 0 0 2 2 2 0 PAS fold SAGA-Tad1 PF12767.7 KIY52792.1 - 2.1e-26 93.1 0.0 2.9e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KIY52792.1 - 0.0098 15.7 0.4 0.015 15.1 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family PRIMA1 PF16101.5 KIY52792.1 - 0.91 9.6 4.3 2.5 8.2 4.3 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4653 PF15546.6 KIY52793.1 - 0.018 14.7 0.9 0.024 14.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) hDGE_amylase PF14701.6 KIY52794.1 - 1e-160 535.6 0.0 1.3e-160 535.3 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KIY52794.1 - 4.8e-119 397.7 0.0 6.3e-119 397.3 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KIY52794.1 - 2.6e-78 263.2 0.0 3.7e-78 262.7 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KIY52794.1 - 2.6e-21 75.5 0.0 5.1e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme UDPGT PF00201.18 KIY52796.1 - 4e-11 42.4 0.0 7e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIY52796.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF4510 PF14971.6 KIY52797.1 - 0.078 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) HVSL PF09749.9 KIY52798.1 - 5.8e-40 137.2 0.1 1e-39 136.4 0.1 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KIY52798.1 - 7.7e-06 25.9 0.1 2e-05 24.5 0.1 1.6 1 1 0 2 2 2 1 2'-5' RNA ligase superfamily Ribonuclease_P PF00825.18 KIY52798.1 - 0.027 14.6 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease P MitMem_reg PF13012.6 KIY52799.1 - 4.8e-24 84.9 0.0 7.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KIY52799.1 - 1.1e-07 31.9 0.0 6.2e-06 26.2 0.0 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TMEM125 PF15109.6 KIY52800.1 - 0.0028 18.0 2.9 0.0061 16.9 2.9 1.5 1 0 0 1 1 1 1 TMEM125 protein family Lactamase_B_2 PF12706.7 KIY52801.1 - 1.3e-30 106.4 0.1 1.8e-30 106.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY52801.1 - 1e-07 32.1 0.1 1.8e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KIY52801.1 - 0.03 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain DUF2420 PF10336.9 KIY52801.1 - 0.17 11.9 0.0 0.46 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) Fungal_trans PF04082.18 KIY52803.1 - 6.7e-05 22.0 0.1 0.00016 20.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KIY52804.1 - 7.2e-57 192.7 0.0 9.4e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52804.1 - 1.5e-29 103.1 0.0 2.6e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY52804.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KIY52804.1 - 0.024 14.0 0.3 0.049 13.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY52804.1 - 0.032 14.2 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KIY52804.1 - 0.066 12.8 0.1 0.5 9.9 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rtf2 PF04641.12 KIY52805.1 - 1e-70 238.1 0.2 1.1e-70 238.0 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KIY52805.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KIY52805.1 - 0.017 15.0 0.1 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 KIY52805.1 - 0.026 14.6 1.2 0.047 13.8 0.3 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger Transgly PF00912.22 KIY52805.1 - 0.029 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase HNH_2 PF13391.6 KIY52807.1 - 0.0022 18.1 0.0 0.0097 16.0 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease HNH_2 PF13391.6 KIY52812.1 - 0.00021 21.4 0.0 0.00065 19.8 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Symplekin_C PF12295.8 KIY52813.1 - 1.5e-64 217.5 3.8 1.9e-64 217.2 0.6 2.7 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KIY52813.1 - 1e-47 162.7 0.0 8.6e-46 156.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3453) HEAT_2 PF13646.6 KIY52813.1 - 0.00044 20.6 1.5 0.68 10.4 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats RhoGAP PF00620.27 KIY52814.1 - 3e-34 118.0 0.0 5.9e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KIY52814.1 - 3.5e-26 91.2 36.3 3.6e-10 39.9 6.8 4.6 5 0 0 5 5 5 4 LIM domain DUF1610 PF07754.11 KIY52815.1 - 0.26 11.3 3.8 0.69 9.9 3.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DnaJ PF00226.31 KIY52816.1 - 1.1e-21 76.8 0.9 1.7e-21 76.1 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain VHS PF00790.19 KIY52817.1 - 1.7e-32 112.2 0.1 3.7e-32 111.1 0.1 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KIY52817.1 - 9.6e-17 60.3 0.1 1.7e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY52817.1 - 8e-15 54.4 0.9 1.5e-14 53.5 0.3 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KIY52817.1 - 7.3e-13 48.0 0.1 1.4e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KIY52817.1 - 6e-11 42.5 1.6 1.9e-10 40.9 1.6 1.9 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KIY52817.1 - 0.00095 18.9 2.0 0.00095 18.9 2.0 2.4 3 0 0 3 3 3 1 Ubiquitin interaction motif DUF4763 PF15960.5 KIY52817.1 - 0.069 12.4 0.5 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) NAT PF04768.13 KIY52818.1 - 3.4e-39 134.2 0.0 5.9e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KIY52818.1 - 5.5e-26 91.4 0.0 1.3e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KIY52818.1 - 6.9e-25 88.0 0.0 1.5e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Sacchrp_dh_NADP PF03435.18 KIY52818.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Death PF00531.22 KIY52820.1 - 0.11 12.6 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Death domain PcfK PF14058.6 KIY52820.1 - 1.6 9.0 5.8 0.38 11.0 0.2 2.0 1 1 1 2 2 2 0 PcfK-like protein F-box-like PF12937.7 KIY52821.1 - 3e-05 23.8 0.0 0.00017 21.4 0.0 2.3 3 1 0 3 3 3 1 F-box-like Plavaka PF18759.1 KIY52823.1 - 2.8e-30 105.7 0.3 3.9e-30 105.2 0.3 1.2 1 0 0 1 1 1 1 Plavaka transposase IKKbetaNEMObind PF12179.8 KIY52823.1 - 0.11 12.6 0.0 6.2 7.0 0.0 2.5 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Terpene_synth_C PF03936.16 KIY52825.1 - 1.4e-07 31.2 0.1 2.4e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF2408 PF10303.9 KIY52826.1 - 2e-58 196.8 0.6 6.9e-40 136.7 0.0 4.6 5 0 0 5 5 5 3 Protein of unknown function (DUF2408) TetR_C_27 PF17935.1 KIY52826.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2087 PF09860.9 KIY52826.1 - 0.12 12.6 0.1 14 5.9 0.1 3.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Brix PF04427.18 KIY52827.1 - 5.2e-23 82.2 0.0 8e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Pkinase PF00069.25 KIY52828.1 - 6.7e-66 222.3 0.0 1.3e-65 221.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52828.1 - 6.3e-36 124.0 0.0 1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY52828.1 - 2.6e-10 40.1 0.0 5.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY52828.1 - 1.5e-06 27.3 0.1 2.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY52828.1 - 0.00023 20.6 2.2 0.0003 20.2 0.1 2.2 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY52828.1 - 0.037 13.0 0.2 0.054 12.4 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIY52828.1 - 0.039 13.9 0.3 0.085 12.8 0.3 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIY52828.1 - 0.056 12.5 0.4 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KIY52828.1 - 0.068 12.1 0.8 0.086 11.8 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase p450 PF00067.22 KIY52829.1 - 5.7e-17 61.6 0.0 9.4e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sdh5 PF03937.16 KIY52830.1 - 1.4e-28 98.6 1.3 1.9e-28 98.2 1.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF202 PF02656.15 KIY52831.1 - 0.048 14.1 0.2 0.094 13.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) ATP19 PF11022.8 KIY52832.1 - 1.3 9.4 3.5 0.54 10.7 0.3 2.1 2 1 0 2 2 2 0 ATP synthase subunit K Zn_clus PF00172.18 KIY52832.1 - 1.3 9.2 5.9 0.52 10.5 1.3 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCHC_2 PF13696.6 KIY52833.1 - 0.04 13.7 8.9 0.13 12.1 8.9 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIY52833.1 - 4.6 7.5 10.8 1.4 9.2 7.6 1.9 2 0 0 2 2 2 0 Zinc knuckle Zn_clus PF00172.18 KIY52834.1 - 0.078 13.1 12.0 1.2 9.3 5.2 2.5 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_C1 PF02167.15 KIY52835.1 - 8.2e-98 326.5 0.0 9.9e-98 326.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KIY52835.1 - 0.00096 19.4 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KIY52835.1 - 0.017 16.3 0.2 0.041 15.0 0.2 1.7 1 1 0 1 1 1 0 Cytochrome c SAC3_GANP PF03399.16 KIY52836.1 - 9.2e-27 94.2 6.1 3.8e-25 88.9 6.1 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KIY52836.1 - 2.8e-07 30.6 0.2 6.8e-07 29.4 0.2 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Myco_haema PF05692.12 KIY52836.1 - 0.0071 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Mycoplasma haemagglutinin Velvet PF11754.8 KIY52837.1 - 1.8e-22 80.5 0.1 1.5e-12 48.0 0.0 2.0 1 1 1 2 2 2 2 Velvet factor Tim17 PF02466.19 KIY52838.1 - 6.3e-25 87.7 5.7 8.3e-25 87.3 5.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TPR_1 PF00515.28 KIY52839.1 - 2.6e-16 58.6 1.3 3.7e-07 29.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY52839.1 - 7.2e-16 57.6 7.7 1.4e-07 31.0 0.5 4.8 3 2 2 5 5 5 3 TPR repeat TPR_2 PF07719.17 KIY52839.1 - 8.5e-15 53.6 6.2 5.3e-07 29.3 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY52839.1 - 2.4e-11 43.8 11.3 0.00012 22.3 0.6 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY52839.1 - 4.2e-11 42.4 0.2 0.024 15.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY52839.1 - 5.1e-11 43.0 3.7 0.00047 20.8 0.0 3.5 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY52839.1 - 1.1e-08 35.5 5.4 4.6e-05 23.8 0.2 3.0 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY52839.1 - 1.1e-08 34.5 3.3 0.0079 16.3 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY52839.1 - 1.3e-07 31.9 7.9 0.013 16.2 0.0 5.3 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY52839.1 - 9.1e-06 26.0 1.1 0.021 15.4 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY52839.1 - 2.5e-05 24.0 8.0 0.0035 17.3 0.0 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIY52839.1 - 3.8e-05 23.1 0.8 6.2e-05 22.3 0.8 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY52839.1 - 0.0001 22.5 1.2 0.086 13.1 0.3 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC5 PF12862.7 KIY52839.1 - 0.00025 21.1 1.0 0.0004 20.4 0.2 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 KIY52839.1 - 0.0039 17.5 2.9 0.11 12.8 0.1 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIY52839.1 - 0.0054 16.6 15.3 0.041 13.8 0.1 4.0 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY52839.1 - 0.01 16.0 1.1 2.9 8.1 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY52839.1 - 0.029 15.0 0.3 0.26 12.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KIY52839.1 - 0.053 12.9 0.5 4.9 6.5 0.0 2.1 1 1 1 2 2 2 0 Coatomer epsilon subunit MIT PF04212.18 KIY52839.1 - 0.063 13.4 4.9 26 5.0 0.2 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 KIY52839.1 - 0.064 13.3 0.7 8.3 6.5 0.1 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 KIY52839.1 - 0.073 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 KIY52839.1 - 0.085 12.2 3.6 0.98 8.7 0.5 2.6 1 1 1 3 3 3 0 MalT-like TPR region Fungal_trans_2 PF11951.8 KIY52839.1 - 0.094 11.5 0.5 0.13 11.1 0.5 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain AAA_33 PF13671.6 KIY52840.1 - 0.00061 20.0 0.1 0.00097 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain PX PF00787.24 KIY52841.1 - 1.7e-20 73.1 0.1 5.1e-20 71.6 0.1 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KIY52841.1 - 2.1e-07 30.7 6.5 0.0032 17.1 0.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KIY52841.1 - 0.018 14.7 0.4 0.018 14.7 0.4 2.1 2 0 0 2 2 2 0 BAR domain LuxT_C PF18285.1 KIY52841.1 - 0.06 13.9 0.2 0.22 12.1 0.2 1.9 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain FAM92 PF06730.11 KIY52841.1 - 0.13 11.7 2.4 0.087 12.2 0.4 1.6 2 0 0 2 2 2 0 FAM92 protein Exonuc_VII_L PF02601.15 KIY52841.1 - 0.99 8.9 3.3 6.2 6.3 0.5 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Pribosyltran PF00156.27 KIY52842.1 - 0.0077 15.8 0.2 0.015 14.8 0.2 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Mito_carr PF00153.27 KIY52843.1 - 4.1e-63 209.4 1.8 2.8e-22 78.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIY52843.1 - 0.0018 17.5 3.1 2.4 7.2 0.2 3.2 1 1 0 3 3 3 3 Gammaproteobacterial serine protease Tim17 PF02466.19 KIY52843.1 - 0.13 12.6 2.2 3.1 8.2 2.2 2.8 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family G-alpha PF00503.20 KIY52844.1 - 7.6e-111 370.7 0.1 8.8e-111 370.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY52844.1 - 5.3e-14 52.0 0.0 2.6e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY52844.1 - 0.0026 17.2 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 KIY52844.1 - 0.038 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KIY52844.1 - 0.05 13.8 0.0 0.79 9.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIY52844.1 - 0.083 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_2 PF00891.18 KIY52845.1 - 6.5e-22 77.9 0.0 4.5e-20 71.8 0.0 2.2 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KIY52845.1 - 0.00042 20.2 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY52845.1 - 0.0021 18.7 0.0 0.0063 17.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY52845.1 - 0.11 13.2 0.0 0.26 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIY52845.1 - 0.11 13.2 0.0 0.26 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIY52845.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KIY52845.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Phage_int_SAM_3 PF14659.6 KIY52846.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain zf-CCCH PF00642.24 KIY52847.1 - 0.015 15.2 1.7 0.037 13.9 1.7 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY52847.1 - 0.23 11.6 3.5 2.4 8.3 3.5 2.3 1 1 0 1 1 1 0 Zinc finger domain Cation_efflux PF01545.21 KIY52849.1 - 2.5e-40 138.3 17.6 2.7e-38 131.7 17.6 2.1 1 1 0 1 1 1 1 Cation efflux family NicO PF03824.16 KIY52849.1 - 0.00069 19.0 5.4 0.00094 18.6 5.4 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein V_ATPase_I PF01496.19 KIY52849.1 - 0.022 12.7 0.0 0.025 12.5 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 KIY52849.1 - 0.023 14.0 21.4 0.019 14.2 15.2 2.3 1 1 1 2 2 2 0 ZIP Zinc transporter HILPDA PF15220.6 KIY52849.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated DUF998 PF06197.13 KIY52849.1 - 0.45 10.1 7.3 0.28 10.8 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Fungal_trans PF04082.18 KIY52850.1 - 2.4e-12 46.5 0.1 4.2e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PDCD2_C PF04194.13 KIY52851.1 - 1.7e-35 122.7 0.0 1.7e-35 122.7 0.0 2.1 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain v110 PF01639.17 KIY52851.1 - 0.23 11.4 1.1 0.42 10.5 1.1 1.4 1 0 0 1 1 1 0 Viral family 110 ParA PF10609.9 KIY52852.1 - 1.1e-92 309.9 0.0 1.3e-92 309.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIY52852.1 - 4.7e-08 33.1 0.0 7.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIY52852.1 - 2.3e-05 23.8 0.9 0.0023 17.2 0.2 2.5 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 KIY52852.1 - 0.0013 18.7 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY52852.1 - 0.0045 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KIY52852.1 - 0.0078 16.0 0.0 0.019 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KIY52852.1 - 0.017 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain CBP_BcsQ PF06564.12 KIY52852.1 - 0.02 14.4 0.0 0.048 13.1 0.0 1.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 KIY52852.1 - 0.04 13.8 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Fer4_NifH PF00142.18 KIY52852.1 - 0.059 12.8 0.0 3.6 6.9 0.0 2.6 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirE PF05272.11 KIY52852.1 - 0.061 13.0 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E TF_Zn_Ribbon PF08271.12 KIY52852.1 - 0.095 12.2 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding AAA_24 PF13479.6 KIY52852.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIY52852.1 - 0.21 11.5 0.4 0.36 10.7 0.4 1.3 1 0 0 1 1 1 0 NACHT domain SH3_1 PF00018.28 KIY52853.1 - 3e-18 65.2 2.4 2.4e-08 33.4 0.2 3.2 2 1 0 2 2 2 2 SH3 domain SAM_2 PF07647.17 KIY52853.1 - 3.2e-14 52.8 0.1 5.8e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIY52853.1 - 6e-14 52.2 0.1 1e-13 51.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KIY52853.1 - 3.6e-13 49.1 2.7 5.4e-06 26.2 0.2 2.7 2 1 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KIY52853.1 - 1.1e-08 34.6 0.4 2.4e-05 23.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 KIY52853.1 - 2.3e-06 28.1 0.0 4.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 KIY52853.1 - 0.0011 19.2 5.6 0.058 13.7 0.7 2.8 2 0 0 2 2 2 2 Bacterial SH3 domain SAM_PNT PF02198.16 KIY52853.1 - 0.0081 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SlyX PF04102.12 KIY52853.1 - 0.89 10.2 2.9 0.86 10.3 0.1 2.3 2 0 0 2 2 2 0 SlyX HNH_2 PF13391.6 KIY52854.1 - 2.7e-08 33.8 0.1 6.6e-08 32.6 0.1 1.7 2 0 0 2 2 2 1 HNH endonuclease T6SS_TssF PF05947.12 KIY52854.1 - 0.0058 15.2 0.0 0.0072 14.9 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system, TssF A_deaminase PF00962.22 KIY52855.1 - 2.2e-22 79.9 0.0 2.5e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Peptidase_M14 PF00246.24 KIY52857.1 - 6.8e-61 206.6 0.0 3.5e-59 201.0 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF746 PF05344.11 KIY52858.1 - 0.0071 16.2 0.0 0.049 13.5 0.0 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF746) OTT_1508_deam PF14441.6 KIY52859.1 - 0.098 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 OTT_1508-like deaminase FH2 PF02181.23 KIY52860.1 - 0.00041 19.6 5.8 0.008 15.3 0.4 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain DUF5320 PF17253.2 KIY52860.1 - 0.00057 20.9 1.4 0.18 12.9 0.0 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF5320) Fez1 PF06818.15 KIY52860.1 - 0.0016 18.9 4.3 0.35 11.3 2.0 2.2 2 0 0 2 2 2 1 Fez1 Fib_alpha PF08702.10 KIY52860.1 - 0.0018 18.5 3.2 0.8 9.9 2.3 2.2 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family ALIX_LYPXL_bnd PF13949.6 KIY52860.1 - 0.0037 16.6 5.1 0.032 13.5 0.0 2.2 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF4201 PF13870.6 KIY52860.1 - 0.006 16.3 12.2 0.2 11.3 0.8 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Spc7 PF08317.11 KIY52860.1 - 0.015 14.2 13.1 0.051 12.5 1.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Rx_N PF18052.1 KIY52860.1 - 0.053 13.8 7.1 0.17 12.2 0.1 2.5 2 0 0 2 2 2 0 Rx N-terminal domain betaPIX_CC PF16523.5 KIY52860.1 - 0.056 13.3 0.7 0.056 13.3 0.7 2.0 2 0 0 2 2 2 0 betaPIX coiled coil TMF_TATA_bd PF12325.8 KIY52860.1 - 0.087 13.1 13.5 0.72 10.1 1.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 KIY52860.1 - 0.089 12.1 9.1 0.36 10.1 0.5 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KIY52860.1 - 0.11 11.6 7.9 1.8 7.6 3.9 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MPS2 PF17060.5 KIY52860.1 - 0.11 11.8 2.6 4.9 6.3 0.1 2.1 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF2353 PF09789.9 KIY52860.1 - 0.14 11.5 9.2 1.6 8.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF1704 PF08014.11 KIY52860.1 - 0.18 10.8 1.9 0.17 10.9 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1704) FlxA PF14282.6 KIY52860.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.7 3 0 0 3 3 2 0 FlxA-like protein SKA1 PF07160.12 KIY52860.1 - 0.2 11.5 4.1 2.7 7.8 0.7 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Fzo_mitofusin PF04799.13 KIY52860.1 - 0.21 11.1 4.1 3.5 7.1 0.8 2.3 2 0 0 2 2 2 0 fzo-like conserved region CENP-F_leu_zip PF10473.9 KIY52860.1 - 0.33 11.0 13.1 0.27 11.3 1.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Swi5 PF07061.11 KIY52860.1 - 0.37 10.9 6.9 0.54 10.4 0.5 2.5 2 0 0 2 2 2 0 Swi5 Filament PF00038.21 KIY52860.1 - 0.37 10.3 11.0 3.4 7.2 0.2 2.1 2 0 0 2 2 2 0 Intermediate filament protein Tropomyosin_1 PF12718.7 KIY52860.1 - 0.52 10.5 15.5 0.86 9.8 2.1 2.2 2 0 0 2 2 2 0 Tropomyosin like Latarcin PF10279.9 KIY52860.1 - 0.64 10.5 4.1 0.8 10.1 0.3 2.3 2 0 0 2 2 2 0 Latarcin precursor TPR_MLP1_2 PF07926.12 KIY52860.1 - 0.77 9.8 20.0 0.66 10.1 2.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KIY52860.1 - 0.84 8.2 4.8 14 4.2 4.5 1.9 1 1 1 2 2 2 0 AAA domain DUF5339 PF17274.2 KIY52860.1 - 0.84 10.5 4.8 25 5.8 0.0 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5339) TolA_bind_tri PF16331.5 KIY52860.1 - 0.85 9.7 11.0 0.21 11.7 0.4 3.3 3 1 0 3 3 3 0 TolA binding protein trimerisation YabA PF06156.13 KIY52860.1 - 0.94 10.2 6.7 2.3 8.9 0.0 2.6 2 1 1 3 3 3 0 Initiation control protein YabA DUF3584 PF12128.8 KIY52860.1 - 0.96 6.9 12.4 0.096 10.2 5.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.8 KIY52860.1 - 1.1 9.4 17.8 0.34 10.9 5.3 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 KIY52860.1 - 1.1 9.3 7.9 5 7.2 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) EzrA PF06160.12 KIY52860.1 - 1.3 7.1 6.4 2 6.5 0.9 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Prefoldin PF02996.17 KIY52860.1 - 1.4 8.8 6.8 5.5 6.9 0.1 3.3 2 1 0 3 3 3 0 Prefoldin subunit Nup88 PF10168.9 KIY52860.1 - 1.5 6.5 4.9 8.9 4.0 0.0 2.0 2 0 0 2 2 2 0 Nuclear pore component DUF2408 PF10303.9 KIY52860.1 - 2.6 8.6 8.8 7.4 7.1 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) LPP PF04728.13 KIY52860.1 - 2.9 8.3 10.0 0.31 11.5 0.3 3.7 3 1 0 3 3 2 0 Lipoprotein leucine-zipper TRAF_BIRC3_bd PF16673.5 KIY52860.1 - 3.2 7.6 8.1 5.4 6.9 0.9 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain COG2 PF06148.11 KIY52860.1 - 3.4 7.8 11.2 2.7 8.1 0.6 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 KIY52860.1 - 3.5 7.8 20.4 1.6 8.9 8.4 2.6 3 0 0 3 3 2 0 Autophagy protein 16 (ATG16) DUF4140 PF13600.6 KIY52860.1 - 3.8 8.0 10.8 5 7.6 0.1 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 KIY52860.1 - 4 7.9 11.5 2.3 8.7 1.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB YscO-like PF16789.5 KIY52860.1 - 4.1 7.4 11.1 0.54 10.3 3.2 2.1 2 0 0 2 2 2 0 YscO-like protein DivIC PF04977.15 KIY52860.1 - 4.7 7.0 8.8 14 5.6 0.6 2.6 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KIY52860.1 - 5 7.7 14.6 6.4 7.3 0.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 KIY52860.1 - 5.6 6.7 12.4 2.9 7.7 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 KIY52860.1 - 7.4 7.5 14.7 7.5 7.5 1.0 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1771 PF08590.10 KIY52861.1 - 1.8e-16 60.2 9.5 3.7e-16 59.2 9.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KIY52861.1 - 3.7e-08 33.1 7.9 5.2e-06 26.3 1.1 2.9 2 1 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KIY52861.1 - 2.5e-07 31.4 2.9 1.4e-05 25.7 0.1 2.4 1 1 1 2 2 2 1 Torus domain zf-CCCH PF00642.24 KIY52861.1 - 2.5e-06 27.3 6.0 0.00038 20.3 0.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.21 KIY52861.1 - 2.4e-05 24.6 0.1 5.3e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 KIY52861.1 - 0.00014 22.2 6.4 0.13 12.8 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 KIY52861.1 - 0.0019 17.9 3.6 0.046 13.5 0.5 2.4 2 0 0 2 2 2 1 Putative zinc-finger domain zf-CCCH_4 PF18044.1 KIY52861.1 - 0.0098 15.7 13.0 0.41 10.5 1.1 3.2 2 1 0 2 2 2 2 CCCH-type zinc finger Lsr2 PF11774.8 KIY52861.1 - 0.049 13.8 0.0 6.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Lsr2 zf-CCCH_3 PF15663.5 KIY52861.1 - 0.12 12.6 3.8 0.69 10.2 3.8 1.9 1 1 0 1 1 1 0 Zinc-finger containing family RRM_1 PF00076.22 KIY52862.1 - 1.1e-29 102.0 0.0 3.8e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY52862.1 - 4.6e-10 39.5 0.1 7.5e-05 22.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KIY52862.1 - 0.0017 18.3 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.6 KIY52862.1 - 0.14 12.0 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) HSP70 PF00012.20 KIY52863.1 - 9.3e-245 813.4 1.3 1.1e-244 813.2 1.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY52863.1 - 1.7e-19 69.8 0.2 1.8e-18 66.4 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KIY52863.1 - 0.00053 19.3 0.7 0.0033 16.7 0.1 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.6 KIY52863.1 - 0.0015 18.9 0.2 0.61 10.5 0.0 3.0 3 0 0 3 3 3 1 Cell division protein FtsA FGGY_C PF02782.16 KIY52863.1 - 0.0029 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KIY52863.1 - 0.014 14.4 0.6 0.086 11.8 0.4 2.2 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain RGS12_us2 PF16611.5 KIY52863.1 - 0.066 13.6 0.7 0.26 11.7 0.7 2.0 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco DUF357 PF04010.13 KIY52863.1 - 0.073 13.1 0.2 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DEC-1_N PF04625.13 KIY52864.1 - 3.3 6.6 10.8 5.2 6.0 10.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region F-box-like PF12937.7 KIY52865.1 - 2.1e-06 27.5 0.1 6.6e-06 25.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like ATG101 PF07855.12 KIY52867.1 - 2.2e-41 141.4 0.0 2.5e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 UDG PF03167.19 KIY52869.1 - 1.9e-13 50.7 0.0 2.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Phage_integrase PF00589.22 KIY52872.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Gal_mutarotas_2 PF13802.6 KIY52873.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Galactose mutarotase-like PX PF00787.24 KIY52874.1 - 9e-16 57.9 0.0 1.4e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 PX domain PHF5 PF03660.14 KIY52875.1 - 2.4e-52 175.5 7.9 2.7e-52 175.3 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KIY52875.1 - 0.039 11.8 4.8 0.043 11.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KIY52875.1 - 0.36 10.9 15.0 1.3 9.2 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KIY52875.1 - 1.4 9.2 17.1 0.29 11.5 2.2 2.6 1 1 1 2 2 2 0 C1 domain TRAUB PF08164.12 KIY52876.1 - 8.9e-29 99.8 0.7 1.8e-28 98.8 0.0 2.0 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KIY52876.1 - 1.9e-22 80.4 0.1 1.9e-22 80.4 0.1 2.5 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF4349 PF14257.6 KIY52876.1 - 0.046 13.1 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PAM2 PF07145.15 KIY52877.1 - 0.042 13.5 0.3 0.11 12.2 0.3 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Mus7 PF09462.10 KIY52878.1 - 1.2e-28 100.4 0.0 1.1e-25 90.6 0.0 2.2 1 1 0 1 1 1 1 Mus7/MMS22 family DUF3752 PF12572.8 KIY52879.1 - 5.1e-32 111.5 5.4 5.1e-32 111.5 5.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) PIN_12 PF16289.5 KIY52879.1 - 0.21 12.1 2.6 3.8 8.0 0.4 2.2 2 0 0 2 2 2 0 PIN domain Pinin_SDK_memA PF04696.13 KIY52879.1 - 3.5 7.7 12.2 0.17 12.0 3.8 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region tRNA_int_endo PF01974.17 KIY52880.1 - 4.5e-18 65.1 1.9 5.3e-17 61.7 1.9 2.2 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KIY52880.1 - 0.0014 18.3 0.0 0.18 11.5 0.0 2.7 3 0 0 3 3 3 1 tRNA intron endonuclease, N-terminal domain PCC_BT PF18140.1 KIY52880.1 - 0.056 13.8 0.1 0.096 13.0 0.1 1.2 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain Fea1 PF07692.11 KIY52880.1 - 0.065 12.3 0.0 0.098 11.7 0.0 1.1 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein WD40 PF00400.32 KIY52881.1 - 3e-06 27.9 14.4 0.087 13.7 0.5 6.6 7 1 0 7 7 7 3 WD domain, G-beta repeat HAND PF09110.11 KIY52881.1 - 0.31 11.8 6.8 0.62 10.8 6.8 1.4 1 0 0 1 1 1 0 HAND Mst1_SARAH PF11629.8 KIY52881.1 - 1.2 9.3 5.7 2.9 8.0 5.7 1.6 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Aminotran_5 PF00266.19 KIY52882.1 - 4.2e-26 91.8 0.0 5.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V KR PF08659.10 KIY52882.1 - 0.027 14.4 0.2 0.05 13.5 0.1 1.5 1 1 0 1 1 1 0 KR domain F-box-like PF12937.7 KIY52883.1 - 0.00028 20.7 0.6 0.001 18.9 0.6 2.0 1 0 0 1 1 1 1 F-box-like DUF1640 PF07798.11 KIY52884.1 - 3e-59 200.0 13.1 3.8e-59 199.7 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) FlaC_arch PF05377.11 KIY52884.1 - 0.018 15.5 6.9 0.033 14.6 1.2 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BshC PF10079.9 KIY52884.1 - 0.03 13.1 5.9 0.046 12.5 5.9 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC XhlA PF10779.9 KIY52884.1 - 0.076 13.2 4.3 2 8.6 0.0 2.9 3 0 0 3 3 3 0 Haemolysin XhlA V_ATPase_I PF01496.19 KIY52884.1 - 0.12 10.3 6.2 0.13 10.2 6.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.18 KIY52884.1 - 0.14 12.4 3.8 0.33 11.2 3.8 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper ArAE_2_N PF10337.9 KIY52884.1 - 0.16 11.0 2.9 0.21 10.6 2.9 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal HMMR_C PF15908.5 KIY52884.1 - 0.2 11.9 8.5 2.1 8.6 0.1 2.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal CrtC PF07143.11 KIY52884.1 - 0.48 11.1 5.6 0.68 10.6 2.3 1.9 1 1 1 2 2 2 0 CrtC N-terminal lipocalin domain COG5 PF10392.9 KIY52884.1 - 0.7 10.1 8.5 2.3 8.4 3.5 2.8 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF5082 PF16888.5 KIY52884.1 - 0.76 10.1 11.0 0.53 10.6 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Phage_GP20 PF06810.11 KIY52884.1 - 0.91 9.3 10.9 1.6 8.5 10.9 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 Phage_lysis PF03245.13 KIY52884.1 - 1.1 9.4 9.3 1 9.5 5.4 2.1 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Uso1_p115_C PF04871.13 KIY52884.1 - 1.1 9.6 12.5 0.52 10.7 9.2 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TolA_bind_tri PF16331.5 KIY52884.1 - 1.3 9.2 15.2 0.32 11.1 8.3 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation DivIC PF04977.15 KIY52884.1 - 1.3 8.8 11.8 0.61 9.9 6.1 2.5 2 1 0 2 2 2 0 Septum formation initiator Baculo_PEP_C PF04513.12 KIY52884.1 - 1.5 8.9 7.9 4 7.5 6.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KIY52884.1 - 2.9 8.1 13.5 0.38 10.9 3.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fungal_TACC PF12709.7 KIY52884.1 - 4.9 7.7 11.1 3.5 8.2 5.8 2.8 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 KIY52884.1 - 5.5 7.7 11.7 8 7.2 7.0 2.7 1 1 1 3 3 3 0 Initiation control protein YabA Cnn_1N PF07989.11 KIY52884.1 - 6.6 7.0 14.5 94 3.3 9.5 3.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 NIR_SIR PF01077.22 KIY52885.1 - 1.4e-48 164.4 0.0 1.6e-45 154.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KIY52885.1 - 3.5e-29 100.5 0.1 2.9e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KIY52885.1 - 1.1e-21 77.5 0.0 1.5e-20 73.8 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin POR_N PF01855.19 KIY52885.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Peptidase_C12 PF01088.21 KIY52886.1 - 6.6e-52 176.3 0.0 7.7e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyco_hydro_7 PF00840.20 KIY52887.1 - 2.6e-201 669.0 20.0 3.1e-201 668.8 20.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DEAD PF00270.29 KIY52888.1 - 1.1e-40 139.2 0.1 1.7e-40 138.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY52888.1 - 1.7e-29 102.4 0.0 4.1e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY52888.1 - 0.0002 21.4 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWIRM-assoc_2 PF16496.5 KIY52888.1 - 0.053 12.4 1.2 0.082 11.8 1.2 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CMS1 PF14617.6 KIY52888.1 - 0.15 11.4 3.6 1.5 8.1 0.0 2.8 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Topoisom_bac PF01131.20 KIY52889.1 - 1.8e-108 363.2 0.0 2.2e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KIY52889.1 - 2.1e-21 76.1 0.0 7.8e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 Toprim domain IBR PF01485.21 KIY52890.1 - 9.4e-15 54.6 43.8 1.2e-09 38.3 6.6 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KIY52890.1 - 1.4e-10 41.4 0.0 3.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 KIY52890.1 - 8.4e-05 22.5 7.7 8.4e-05 22.5 7.7 4.1 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY52890.1 - 8.6e-05 22.8 7.7 8.6e-05 22.8 7.7 5.1 3 2 2 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KIY52890.1 - 0.0016 18.3 7.7 0.0016 18.3 7.7 4.6 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY52890.1 - 0.0027 17.5 5.9 0.0027 17.5 5.9 5.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY52890.1 - 0.0088 15.8 7.8 0.0088 15.8 7.8 2.3 2 0 0 2 2 2 1 RING-like zinc finger NMO PF03060.15 KIY52891.1 - 2.3e-31 109.4 3.8 8e-30 104.3 3.8 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KIY52891.1 - 3.1e-05 23.2 0.2 4.4e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KIY52891.1 - 0.00051 19.3 0.1 0.00079 18.7 0.1 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KIY52891.1 - 0.077 12.4 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein CPSase_L_D2 PF02786.17 KIY52892.1 - 9.8e-81 270.3 0.1 2.4e-80 269.0 0.1 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KIY52892.1 - 1.4e-66 224.1 0.0 2.2e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KIY52892.1 - 1e-39 135.5 0.1 2.1e-39 134.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIY52892.1 - 6e-30 103.5 0.0 2.7e-29 101.4 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KIY52892.1 - 1.9e-29 103.0 0.0 5e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KIY52892.1 - 1.7e-17 63.0 3.4 3.9e-17 61.8 3.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KIY52892.1 - 2.4e-12 46.5 3.7 8.1e-06 25.6 0.3 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KIY52892.1 - 4e-10 39.6 0.0 8.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIY52892.1 - 3.4e-09 36.5 0.0 1.3e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 KIY52892.1 - 5.5e-06 27.0 1.2 0.14 12.9 0.2 2.8 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 KIY52892.1 - 7.6e-06 25.3 0.9 0.0032 16.7 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KIY52892.1 - 2.6e-05 24.3 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KIY52892.1 - 0.00016 21.3 0.0 0.00041 20.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 KIY52892.1 - 0.00064 19.6 0.6 0.0073 16.2 0.3 2.8 3 0 0 3 3 3 1 Glycine cleavage H-protein GARS_A PF01071.19 KIY52892.1 - 0.0024 17.7 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_M23 PF01551.22 KIY52892.1 - 0.02 15.1 0.3 0.15 12.3 0.3 2.6 1 1 0 1 1 1 0 Peptidase family M23 NQRA PF05896.11 KIY52892.1 - 0.029 13.8 0.3 0.059 12.8 0.3 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RimK PF08443.11 KIY52892.1 - 0.033 13.8 0.0 0.19 11.3 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain RnfC_N PF13375.6 KIY52892.1 - 0.042 13.8 0.5 0.2 11.6 0.6 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 KIY52892.1 - 0.092 12.7 0.7 1.2 9.0 0.7 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) RhoGAP PF00620.27 KIY52893.1 - 4.7e-39 133.6 0.0 1.1e-38 132.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KIY52893.1 - 3.7e-15 56.3 0.0 7.7e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.24 KIY52893.1 - 1.3e-07 31.6 0.0 3.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 PX domain CortBP2 PF09727.9 KIY52893.1 - 0.0067 16.4 2.0 0.017 15.0 2.0 1.6 1 0 0 1 1 1 1 Cortactin-binding protein-2 PH_8 PF15409.6 KIY52893.1 - 0.0078 16.5 0.0 0.059 13.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain HAUS6_N PF14661.6 KIY52893.1 - 5.9 6.4 10.6 0.12 12.0 3.7 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PARP PF00644.20 KIY52894.1 - 6.1e-11 42.3 0.0 9.6e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ECSIT_C PF14784.6 KIY52894.1 - 0.039 14.3 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein SHR3_chaperone PF08229.11 KIY52895.1 - 2.5e-49 166.8 1.3 2.7e-49 166.7 1.3 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Ribosomal_S19 PF00203.21 KIY52901.1 - 1.8e-32 111.1 0.1 2.7e-32 110.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 KIY52901.1 - 0.17 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH Acylphosphatase PF00708.18 KIY52902.1 - 3.8e-16 59.3 0.0 4e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase La PF05383.17 KIY52903.1 - 1.4e-05 25.0 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 La domain SDH_alpha PF03313.15 KIY52904.1 - 2.1e-100 335.7 1.4 2.7e-100 335.3 1.4 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KIY52904.1 - 5.3e-50 169.8 0.0 9.6e-50 169.0 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain BshC PF10079.9 KIY52905.1 - 0.0014 17.5 4.6 0.0016 17.3 4.6 1.0 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC Snapin_Pallidin PF14712.6 KIY52905.1 - 0.056 13.9 2.0 0.056 13.9 2.0 2.1 1 1 1 2 2 2 0 Snapin/Pallidin GAS PF13851.6 KIY52905.1 - 0.062 12.6 8.3 0.11 11.9 8.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KIY52905.1 - 0.12 12.6 7.4 0.17 12.1 7.4 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CCDC-167 PF15188.6 KIY52905.1 - 0.21 11.9 6.3 0.34 11.3 6.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4570 PF15134.6 KIY52905.1 - 0.22 11.6 9.1 0.37 10.8 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) T2SSM PF04612.12 KIY52905.1 - 0.34 11.0 5.6 0.49 10.4 5.6 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Atg14 PF10186.9 KIY52905.1 - 0.35 9.9 5.5 0.41 9.7 5.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF883 PF05957.13 KIY52905.1 - 0.38 11.4 7.8 0.61 10.7 7.8 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FA_hydroxylase PF04116.13 KIY52906.1 - 3.4e-23 82.5 14.1 3.4e-23 82.5 14.1 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF5486 PF17588.2 KIY52906.1 - 0.0052 16.6 2.1 0.01 15.7 2.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5486) Clathrin PF00637.20 KIY52907.1 - 1.6e-203 666.8 33.1 2.1e-32 112.0 0.5 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KIY52907.1 - 1.5e-31 107.1 0.2 9.9e-07 28.8 0.1 6.7 6 0 0 6 6 6 4 Clathrin propeller repeat Clathrin_H_link PF13838.6 KIY52907.1 - 3.4e-31 106.9 0.1 2.3e-30 104.3 0.1 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 KIY52907.1 - 4.5e-12 45.1 2.8 9.6e-12 44.1 0.0 3.0 3 0 0 3 3 3 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KIY52907.1 - 6.7e-05 22.1 6.9 0.39 9.7 0.0 3.9 4 0 0 4 4 4 3 Coatomer WD associated region TPR_14 PF13428.6 KIY52907.1 - 0.0074 17.0 14.4 2.1 9.4 0.0 8.3 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY52907.1 - 0.01 15.6 1.2 15 5.6 0.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY52907.1 - 0.023 14.9 5.2 22 5.6 0.0 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY52907.1 - 0.033 14.2 9.7 2.8 8.2 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat MRPL52 PF18699.1 KIY52907.1 - 0.24 11.6 0.9 0.59 10.4 0.9 1.6 1 0 0 1 1 1 0 Mitoribosomal protein mL52 TPR_2 PF07719.17 KIY52907.1 - 0.33 11.2 10.3 42 4.6 0.4 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY52907.1 - 0.89 10.1 3.0 62 4.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Rcd1 PF04078.13 KIY52908.1 - 2e-122 407.5 5.7 2.2e-122 407.3 5.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Ribosomal_L28e PF01778.17 KIY52909.1 - 6.9e-38 129.9 2.7 6.9e-38 129.9 2.7 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KIY52909.1 - 1.7e-28 99.1 14.7 1.7e-28 99.1 14.7 2.2 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KIY52909.1 - 0.00015 21.2 16.1 0.00019 20.9 16.1 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KIY52909.1 - 0.019 14.7 0.7 0.031 14.0 0.7 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain CDC45 PF02724.14 KIY52909.1 - 0.79 7.9 15.3 0.99 7.6 15.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KIY52909.1 - 3.3 5.8 22.8 4.3 5.4 22.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3684 PF12449.8 KIY52910.1 - 0 1136.8 0.0 0 1136.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) SRP54_N PF02881.19 KIY52910.1 - 0.048 13.9 0.2 0.16 12.2 0.2 1.9 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain DUF3810 PF12725.7 KIY52910.1 - 2.2 7.5 4.2 5.4 6.3 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Prp31_C PF09785.9 KIY52912.1 - 0.89 10.5 7.4 0.33 11.9 2.2 2.3 2 0 0 2 2 2 0 Prp31 C terminal domain Ysc84 PF04366.12 KIY52913.1 - 1.7e-32 111.9 0.4 2.4e-32 111.4 0.4 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KIY52913.1 - 2.7e-15 55.7 0.1 5.8e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY52913.1 - 8.5e-15 54.4 0.0 2.8e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KIY52913.1 - 6.7e-11 41.7 0.0 5.7e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain DUF3104 PF11302.8 KIY52913.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3104) RRM_1 PF00076.22 KIY52914.1 - 1.1e-10 41.2 0.0 1.5e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY52914.1 - 0.0026 17.3 0.0 0.0028 17.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KIY52918.1 - 2.9e-12 46.2 0.0 5.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BCS1_N PF08740.11 KIY52919.1 - 6.1e-25 88.3 0.1 1.1e-24 87.5 0.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KIY52919.1 - 2.7e-20 73.2 0.0 1.8e-11 44.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIY52919.1 - 3.7e-05 23.5 0.0 6.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY52919.1 - 0.00051 20.0 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KIY52919.1 - 0.00058 19.7 0.2 0.0012 18.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY52919.1 - 0.00062 19.3 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KIY52919.1 - 0.0081 16.5 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KIY52919.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_6 PF12774.7 KIY52919.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 KIY52919.1 - 0.013 15.8 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KIY52919.1 - 0.025 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIY52919.1 - 0.039 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 KIY52919.1 - 0.047 12.9 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 KIY52919.1 - 0.074 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIY52919.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4605 PF15378.6 KIY52920.1 - 0.12 12.3 4.7 0.052 13.4 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) EamA PF00892.20 KIY52921.1 - 2.4e-07 31.0 28.4 8.3e-07 29.3 6.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Arylsulfotran_2 PF14269.6 KIY52922.1 - 7.7e-44 150.2 1.4 7.4e-35 120.7 0.4 2.3 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY52922.1 - 1.9e-11 43.5 0.3 5.1e-10 38.8 0.3 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ras PF00071.22 KIY52923.1 - 4.4e-52 175.9 0.0 5e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY52923.1 - 5.6e-21 75.0 0.0 9e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY52923.1 - 8.3e-07 28.6 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIY52923.1 - 0.00034 20.1 0.0 0.00055 19.4 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Skp1_POZ PF03931.15 KIY52923.1 - 0.011 15.9 0.2 0.03 14.5 0.1 1.7 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain MMR_HSR1 PF01926.23 KIY52923.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY52923.1 - 0.03 14.2 0.0 7.1 6.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KIY52923.1 - 0.056 12.8 0.0 0.076 12.3 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KIY52923.1 - 0.083 13.3 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NUDIX PF00293.28 KIY52924.1 - 5e-10 39.5 0.0 7.1e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain Vma12 PF11712.8 KIY52925.1 - 1.3e-08 35.0 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4231 PF14015.6 KIY52925.1 - 0.16 12.4 3.2 0.093 13.2 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Atx10homo_assoc PF09759.9 KIY52926.1 - 7.7e-27 93.2 0.3 2e-26 91.9 0.3 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain ADH_N PF08240.12 KIY52927.1 - 9.8e-22 76.9 0.1 2.5e-21 75.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY52927.1 - 2.8e-19 69.4 0.3 5e-19 68.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY52927.1 - 2.2e-11 45.0 0.1 3.7e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY52927.1 - 0.0054 16.2 0.1 0.0076 15.8 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KIY52927.1 - 0.02 14.2 5.5 0.22 10.8 4.9 2.6 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MS_channel PF00924.18 KIY52928.1 - 3e-19 69.4 0.9 5.8e-19 68.5 0.9 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIY52928.1 - 0.0084 15.6 0.1 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KIY52928.1 - 0.012 15.5 0.1 0.049 13.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain GCN5L1 PF06320.13 KIY52928.1 - 0.24 11.6 0.9 28 4.9 0.0 2.4 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Fungal_trans PF04082.18 KIY52929.1 - 8.2e-22 77.5 0.4 1.7e-21 76.5 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY52929.1 - 4.6e-05 23.4 10.4 8.3e-05 22.6 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tnp_zf-ribbon_2 PF13842.6 KIY52929.1 - 1.2 10.0 5.8 2.9 8.8 5.8 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon PMM PF03332.13 KIY52930.1 - 1.8e-108 361.4 0.3 2.1e-108 361.2 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KIY52930.1 - 1.3e-05 25.1 0.0 9.7e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY52930.1 - 0.025 14.9 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KIY52930.1 - 0.055 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase bVLRF1 PF18826.1 KIY52931.1 - 1.6e-65 219.5 0.0 2.6e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_2 PF12796.7 KIY52931.1 - 0.037 14.6 0.0 0.088 13.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF3449 PF11931.8 KIY52931.1 - 0.066 13.0 0.5 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) FAD_binding_3 PF01494.19 KIY52932.1 - 5.2e-29 101.6 0.5 1.2e-19 70.8 0.0 3.2 2 1 1 3 3 3 3 FAD binding domain F-box-like PF12937.7 KIY52932.1 - 0.0016 18.3 1.5 0.0061 16.4 1.5 2.1 1 0 0 1 1 1 1 F-box-like Leo1 PF04004.13 KIY52934.1 - 1.3e-42 145.5 0.1 1.3e-42 145.5 0.1 2.2 2 0 0 2 2 2 1 Leo1-like protein SQHop_cyclase_C PF13243.6 KIY52935.1 - 5.1e-51 173.7 2.9 8.7e-48 163.0 0.4 2.7 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KIY52935.1 - 1.1e-45 155.9 0.0 3.4e-38 131.4 0.0 3.6 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KIY52935.1 - 6e-30 102.7 6.8 1.1e-08 34.7 0.3 6.3 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KIY52935.1 - 0.012 15.0 0.1 10 5.4 0.0 3.8 3 1 1 4 4 4 0 Pectic acid lyase TED_complement PF07678.14 KIY52935.1 - 0.019 14.0 0.1 1 8.3 0.0 3.3 1 1 2 4 4 4 0 A-macroglobulin TED domain Actin PF00022.19 KIY52936.1 - 6e-30 104.2 0.0 2.4e-29 102.2 0.0 1.8 1 1 0 1 1 1 1 Actin GET2 PF08690.10 KIY52937.1 - 3.7e-11 43.3 0.0 5.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 GET complex subunit GET2 L51_S25_CI-B8 PF05047.16 KIY52938.1 - 5.7e-06 26.1 0.1 9e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1539 PF07560.11 KIY52938.1 - 0.0095 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1539) YL1 PF05764.13 KIY52939.1 - 2.1e-32 113.2 28.5 3.1e-32 112.6 28.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KIY52939.1 - 5.1e-11 42.1 0.0 8.7e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Roughex PF06020.11 KIY52939.1 - 0.1 11.7 13.5 0.27 10.3 13.5 1.7 1 0 0 1 1 1 0 Drosophila roughex protein SDA1 PF05285.12 KIY52939.1 - 0.14 11.5 20.4 0.24 10.8 20.4 1.3 1 0 0 1 1 1 0 SDA1 Peptidase_M20 PF01546.28 KIY52940.1 - 9.5e-25 87.5 0.0 2.1e-24 86.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY52940.1 - 9.6e-12 44.8 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-CCCH PF00642.24 KIY52941.1 - 3.4e-14 52.3 26.4 5e-08 32.7 4.4 4.5 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY52941.1 - 7.7e-09 35.3 33.0 0.00012 22.0 9.7 4.3 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH_3 PF15663.5 KIY52941.1 - 1.9e-06 28.1 13.6 0.0024 18.1 0.1 3.2 2 1 1 3 3 3 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KIY52941.1 - 0.00023 20.9 4.3 0.00023 20.9 4.3 3.8 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KIY52941.1 - 0.073 13.6 37.8 0.39 11.3 5.4 4.9 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KIY52941.1 - 0.13 13.0 15.1 0.46 11.2 1.3 3.6 2 1 1 3 3 3 0 Torus domain RRM_1 PF00076.22 KIY52941.1 - 0.14 12.0 0.0 3.5 7.5 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M50B PF13398.6 KIY52942.1 - 1.1e-38 132.8 16.6 1.3e-38 132.7 16.6 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Fis1_TPR_C PF14853.6 KIY52943.1 - 1.3e-22 79.6 0.2 2e-22 79.0 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KIY52943.1 - 3.5e-15 55.4 0.0 5.5e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KIY52943.1 - 0.00023 21.0 0.2 0.00055 19.9 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY52943.1 - 0.0067 16.2 0.5 0.013 15.3 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY52943.1 - 0.0083 16.7 0.0 0.025 15.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY52943.1 - 0.011 16.3 0.3 0.027 15.0 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY52943.1 - 0.033 14.4 0.1 0.053 13.7 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KIY52943.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.22 KIY52944.1 - 7.2e-31 105.8 1.7 6.2e-16 58.0 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY52944.1 - 5.9e-05 23.1 0.0 0.0034 17.5 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 KIY52944.1 - 0.0001 22.1 0.0 0.24 11.3 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KIY52944.1 - 0.026 14.5 0.3 3.9 7.5 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Cnd2 PF05786.14 KIY52946.1 - 6.3e-138 461.7 12.7 1e-94 318.8 6.8 3.1 1 1 1 2 2 2 2 Condensin complex subunit 2 CNDH2_N PF06278.11 KIY52946.1 - 0.13 12.4 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal F-box-like PF12937.7 KIY52948.1 - 1.1e-06 28.4 0.2 4.4e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like zf-RING-like PF08746.11 KIY52948.1 - 2.8 8.3 5.8 1 9.8 0.8 2.4 2 0 0 2 2 2 0 RING-like domain Evr1_Alr PF04777.13 KIY52950.1 - 1.1e-24 86.8 0.0 1.2e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Erv1 / Alr family Pkinase PF00069.25 KIY52951.1 - 5.4e-74 248.9 0.0 6.4e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY52951.1 - 1.1e-31 110.1 0.0 2.7e-31 108.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY52951.1 - 0.0001 21.8 0.1 0.093 12.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KIY52951.1 - 0.0073 15.3 0.1 0.97 8.3 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KIY52951.1 - 0.016 15.1 0.1 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DnaJ PF00226.31 KIY52952.1 - 1.4e-19 70.0 0.1 3.2e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain OHCU_decarbox PF09349.10 KIY52953.1 - 1.6e-34 119.6 0.0 2e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Pax7 PF12360.8 KIY52953.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Paired box protein 7 zf-H2C2_2 PF13465.6 KIY52954.1 - 5.4e-29 99.3 28.5 1.7e-09 37.7 0.7 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KIY52954.1 - 2.4e-21 74.9 25.0 6.1e-07 29.5 0.4 4.7 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY52954.1 - 7.5e-18 63.7 22.8 2.6e-05 24.7 0.5 4.6 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY52954.1 - 1.6e-08 34.6 11.8 0.0039 17.4 0.1 4.1 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIY52954.1 - 1.6e-06 28.3 11.1 0.001 19.3 3.3 3.1 1 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KIY52954.1 - 3.2e-06 27.0 22.3 0.0098 15.9 0.4 4.9 4 1 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KIY52954.1 - 9.7e-06 25.8 18.0 0.073 13.5 2.0 4.3 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KIY52954.1 - 0.00012 22.3 12.5 0.00028 21.1 0.8 2.6 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KIY52954.1 - 0.00029 21.1 5.7 0.0011 19.2 3.2 2.5 1 1 2 3 3 3 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 KIY52954.1 - 0.00037 20.9 12.9 0.14 12.7 1.5 3.5 2 2 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KIY52954.1 - 0.00065 19.4 13.1 0.35 10.7 0.1 4.0 4 0 0 4 4 4 2 zinc-finger C2H2-type zf_UBZ PF18439.1 KIY52954.1 - 0.001 18.6 4.2 2.2 8.0 0.1 3.5 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KIY52954.1 - 0.0015 18.3 4.2 7.5 6.5 0.0 3.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KIY52954.1 - 0.0044 16.6 3.1 0.32 10.6 0.3 3.4 2 1 1 3 3 3 1 MYST family zinc finger domain BolA PF01722.18 KIY52954.1 - 0.0051 17.1 2.2 2.9 8.2 0.1 3.0 1 1 2 3 3 3 1 BolA-like protein zinc_ribbon_15 PF17032.5 KIY52954.1 - 0.006 17.3 6.3 0.055 14.2 0.4 2.1 1 1 0 2 2 2 1 zinc-ribbon family C1_1 PF00130.22 KIY52954.1 - 0.0096 15.8 10.0 1.5 8.8 0.1 3.6 2 1 2 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HTH_18 PF12833.7 KIY52954.1 - 0.012 15.9 0.4 3.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2256 PF10013.9 KIY52954.1 - 0.015 15.4 3.3 15 5.8 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) FOXP-CC PF16159.5 KIY52954.1 - 0.021 15.5 3.5 2 9.1 0.0 3.3 2 2 1 3 3 3 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 KIY52954.1 - 0.023 14.6 12.5 0.095 12.6 0.2 3.7 4 1 0 4 4 3 0 zinc-finger of a C2HC-type zf-FCS PF06467.14 KIY52954.1 - 0.025 14.5 5.7 3 7.8 0.9 3.7 3 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_5 PF13909.6 KIY52954.1 - 0.036 13.8 0.1 0.036 13.8 0.1 6.4 7 0 0 7 7 7 0 C2H2-type zinc-finger domain LIM PF00412.22 KIY52954.1 - 0.039 14.2 9.3 6.2 7.1 0.3 3.3 2 1 0 3 3 3 0 LIM domain C1_2 PF03107.16 KIY52954.1 - 0.058 13.7 13.0 1.9 8.8 0.2 3.8 2 2 1 3 3 3 0 C1 domain NADH-G_4Fe-4S_3 PF10588.9 KIY52954.1 - 0.071 12.7 3.6 17 5.0 0.1 3.5 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region FYDLN_acid PF09538.10 KIY52954.1 - 0.074 13.7 1.6 24 5.7 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2H2_3rep PF18868.1 KIY52954.1 - 0.081 13.6 8.7 22 5.8 0.1 3.2 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-HIT PF04438.16 KIY52954.1 - 0.16 11.8 8.4 2.6 8.0 0.3 3.4 3 0 0 3 3 3 0 HIT zinc finger zf-SNAP50_C PF12251.8 KIY52954.1 - 0.22 11.2 7.0 0.57 9.8 2.3 2.1 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal C1_4 PF07975.12 KIY52954.1 - 0.27 11.5 8.2 0.22 11.8 1.2 2.5 2 2 0 2 2 2 0 TFIIH C1-like domain Elf1 PF05129.13 KIY52954.1 - 0.55 10.3 9.0 0.47 10.5 1.5 2.4 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KIY52954.1 - 0.59 10.3 9.3 0.44 10.7 0.7 2.8 2 2 0 2 2 2 0 Zinc ribbon domain XPA_N PF01286.18 KIY52954.1 - 0.79 9.8 6.5 10 6.2 0.2 3.4 3 0 0 3 3 3 0 XPA protein N-terminal DUF2072 PF09845.9 KIY52954.1 - 0.98 9.7 4.5 37 4.6 0.1 3.0 3 0 0 3 3 3 0 Zn-ribbon containing protein zf-CRD PF17979.1 KIY52954.1 - 1.4 9.0 10.4 2.8 8.0 0.4 2.2 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions zf_C2H2_ZHX PF18387.1 KIY52954.1 - 1.7 8.4 10.2 14 5.4 0.0 3.5 1 1 3 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-trcl PF13451.6 KIY52954.1 - 2 8.4 6.5 21 5.1 0.1 3.2 3 0 0 3 3 3 0 Probable zinc-ribbon domain IBR PF01485.21 KIY52954.1 - 3.4 7.9 11.1 43 4.4 5.4 3.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain DUF2225 PF09986.9 KIY52954.1 - 4.1 7.1 7.1 16 5.1 0.8 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Actin_micro PF17003.5 KIY52954.1 - 4.7 6.3 6.5 4.2 6.4 0.5 2.3 2 1 0 2 2 2 0 Putative actin-like family zf-AN1 PF01428.16 KIY52954.1 - 4.8 7.4 17.4 15 5.8 2.6 4.2 2 1 2 4 4 4 0 AN1-like Zinc finger FYVE PF01363.21 KIY52954.1 - 4.9 7.4 15.5 2.2 8.5 4.4 3.0 1 1 2 3 3 3 0 FYVE zinc finger zinc_ribbon_4 PF13717.6 KIY52954.1 - 5.9 6.9 11.9 18 5.3 0.4 3.8 3 1 0 3 3 3 0 zinc-ribbon domain DUF629 PF04780.12 KIY52954.1 - 6 5.3 8.4 8.3 4.8 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) HisG PF01634.18 KIY52955.1 - 1.6e-52 177.7 0.0 2.5e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KIY52955.1 - 2.5e-26 91.6 0.4 8.9e-26 89.8 0.1 2.1 3 0 0 3 3 3 1 HisG, C-terminal domain NMT1 PF09084.11 KIY52955.1 - 0.0016 18.4 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Methyltransf_20 PF12147.8 KIY52955.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FCH PF00611.23 KIY52956.1 - 1.2e-07 31.9 0.3 2.9e-07 30.7 0.1 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.27 KIY52956.1 - 7.4e-07 29.1 0.0 2.2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KIY52956.1 - 0.00048 20.1 0.0 0.0024 17.9 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HD_5 PF13487.6 KIY52956.1 - 0.19 12.0 0.6 5.5 7.3 0.1 2.5 2 0 0 2 2 2 0 HD domain RhoGAP PF00620.27 KIY52957.1 - 2.2e-47 160.7 0.0 5e-47 159.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KIY52957.1 - 1.8e-13 50.6 1.8 2.2e-13 50.3 0.2 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF745 PF05335.13 KIY52957.1 - 0.017 14.9 3.9 0.03 14.1 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Cauli_AT PF03233.13 KIY52957.1 - 0.055 13.4 0.7 0.13 12.2 0.7 1.6 1 0 0 1 1 1 0 Aphid transmission protein DUF1664 PF07889.12 KIY52957.1 - 0.13 12.3 3.2 18 5.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KIY52957.1 - 0.15 11.8 7.6 0.23 11.3 3.2 2.6 3 0 0 3 3 3 0 Septum formation initiator SKA2 PF16740.5 KIY52957.1 - 0.17 11.7 4.6 0.4 10.5 3.5 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF948 PF06103.11 KIY52957.1 - 0.18 12.0 1.5 2.6 8.4 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 KIY52957.1 - 0.3 10.6 2.4 0.48 9.9 1.4 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit ApoLp-III PF07464.11 KIY52957.1 - 0.32 11.1 3.7 0.21 11.7 1.5 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TMPIT PF07851.13 KIY52957.1 - 0.35 10.1 2.8 1.2 8.3 1.9 1.9 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin-6_N PF09177.11 KIY52957.1 - 2 9.0 5.5 15 6.2 2.3 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 KIY52957.1 - 4.6 7.4 7.5 0.59 10.3 1.4 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family F-box-like PF12937.7 KIY52958.1 - 3.5e-10 39.6 1.7 3.5e-10 39.6 1.7 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY52958.1 - 1.7e-07 31.0 2.7 1.9e-07 30.8 0.5 2.4 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KIY52958.1 - 0.00011 22.0 1.7 0.00047 20.0 1.3 2.2 1 1 1 2 2 2 1 F-box CENP-T_C PF15511.6 KIY52959.1 - 2.8e-07 30.6 0.1 3.4e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIY52959.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIY52959.1 - 0.00012 22.3 0.0 0.00016 22.0 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY52959.1 - 0.00091 19.5 0.1 0.0018 18.5 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY52959.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIY52959.1 - 0.056 13.5 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KIY52960.1 - 4.4e-50 169.4 3.8 4.9e-50 169.3 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIY52960.1 - 2.6e-05 24.5 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIY52960.1 - 5.2e-05 23.3 0.1 9.9e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KIY52960.1 - 0.00021 21.9 1.2 0.00025 21.6 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KIY52960.1 - 0.00077 19.7 0.1 0.0014 18.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KIY52960.1 - 0.089 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KIY52960.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF515 PF04415.12 KIY52961.1 - 0.27 9.6 3.7 0.31 9.4 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Forkhead PF00250.18 KIY52962.1 - 1.6e-26 92.4 0.0 2.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Mito_carr PF00153.27 KIY52963.1 - 9.7e-30 102.4 8.8 9.2e-18 64.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.25 KIY52964.1 - 2.4e-07 31.0 0.0 3.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY52964.1 - 6.3e-05 23.3 0.0 9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY52964.1 - 0.00013 21.9 0.0 0.00018 21.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PBECR5 PF18814.1 KIY52965.1 - 0.068 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 Chromo_shadow PF01393.19 KIY52966.1 - 4e-16 58.9 0.2 2.9e-14 52.9 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 KIY52966.1 - 3.7e-13 49.2 1.6 1.3e-12 47.4 0.4 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain FAM176 PF14851.6 KIY52966.1 - 4.7 6.9 11.8 7 6.3 3.2 2.4 2 0 0 2 2 2 0 FAM176 family Methyltransf_16 PF10294.9 KIY52967.1 - 1.8e-24 86.4 0.0 1.1e-23 83.8 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIY52967.1 - 2.2e-05 24.4 0.0 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY52967.1 - 0.11 13.3 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 KIY52968.1 - 5.2e-17 61.4 0.0 7.7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY52968.1 - 0.035 14.1 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 KIY52968.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-MYND PF01753.18 KIY52969.1 - 2.7e-10 40.1 8.4 3.9e-10 39.7 8.4 1.2 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIY52969.1 - 0.006 16.7 9.2 0.087 12.9 9.2 2.1 1 1 1 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 KIY52969.1 - 0.55 10.1 7.0 0.98 9.4 7.0 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 KIY52969.1 - 0.61 10.4 6.3 1 9.7 6.3 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ECR1_N PF14382.6 KIY52970.1 - 6.1e-14 51.5 0.1 1.1e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KIY52970.1 - 3e-13 49.9 0.0 6.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KIY52970.1 - 0.032 14.9 0.6 0.97 10.1 0.1 2.9 2 1 1 3 3 3 0 Exosome component EXOSC1/CSL4 Nucleo_P87 PF07267.11 KIY52971.1 - 0.066 12.1 0.5 0.075 11.9 0.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 KIY52971.1 - 0.5 9.6 11.6 0.6 9.4 11.6 1.1 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 KIY52971.1 - 0.93 7.5 5.4 1 7.3 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_methylase PF00145.17 KIY52972.1 - 7e-29 101.2 0.0 1.1e-28 100.5 0.0 1.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase NUDIX PF00293.28 KIY52973.1 - 1.4e-07 31.6 0.0 1.6e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain RINGv PF12906.7 KIY52974.1 - 5.3e-16 58.5 7.7 9e-16 57.7 7.7 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KIY52974.1 - 0.02 15.2 9.5 0.033 14.5 9.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KIY52974.1 - 0.92 9.3 8.3 1.6 8.6 8.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KIY52974.1 - 3.9 7.9 5.3 7 7.0 5.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 KIY52974.1 - 9.5 6.2 6.9 16 5.4 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arginosuc_synth PF00764.19 KIY52975.1 - 5.7e-154 513.1 0.0 6.8e-154 512.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KIY52975.1 - 0.0008 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KIY52975.1 - 0.005 15.7 0.1 0.034 12.9 0.0 2.0 1 1 1 2 2 2 1 tRNA methyl transferase WD40 PF00400.32 KIY52977.1 - 6.5e-09 36.3 0.1 0.0038 18.0 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY52977.1 - 0.0054 17.0 0.0 0.017 15.4 0.0 1.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY52977.1 - 0.23 10.4 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-C3HC4_2 PF13923.6 KIY52978.1 - 6.5e-08 32.3 2.6 6.5e-08 32.3 2.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY52978.1 - 3.4e-07 30.2 1.1 3.4e-07 30.2 1.1 1.7 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIY52978.1 - 6.5e-06 26.0 3.6 1.4e-05 25.0 3.6 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY52978.1 - 8.5e-06 25.6 5.1 2.6e-05 24.0 5.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY52978.1 - 2.1e-05 24.3 9.8 0.00026 20.8 9.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIY52978.1 - 4.8e-05 23.2 0.9 0.00011 21.9 0.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KIY52978.1 - 6.4e-05 23.0 9.0 0.00021 21.4 9.1 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIY52978.1 - 0.00012 22.3 11.3 0.0005 20.4 11.3 2.0 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIY52978.1 - 0.0069 16.2 12.5 0.036 13.9 6.0 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KIY52978.1 - 0.012 15.8 1.6 0.025 14.7 1.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 KIY52978.1 - 0.02 14.5 1.3 0.02 14.5 1.3 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_14 PF17978.1 KIY52978.1 - 0.11 12.9 1.7 0.22 12.0 1.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KIY52978.1 - 2.9 8.2 7.8 12 6.3 7.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain PSK_trans_fac PF07704.11 KIY52979.1 - 0.4 11.5 3.1 3.4 8.5 0.2 2.7 2 1 0 2 2 2 0 Rv0623-like transcription factor DUF5302 PF17227.2 KIY52979.1 - 0.59 11.2 3.6 7 7.7 0.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5302) SIR2 PF02146.17 KIY52980.1 - 9e-60 201.6 0.0 1.5e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KIY52980.1 - 1.7e-06 27.8 0.0 4.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KIY52980.1 - 0.007 16.1 0.5 2.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DEAD PF00270.29 KIY52981.1 - 3.3e-46 157.3 0.0 6e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY52981.1 - 6.3e-29 100.5 0.0 2e-28 98.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY52981.1 - 0.049 13.6 0.0 0.17 11.9 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIY52981.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KIY52981.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2183 PF09949.9 KIY52982.1 - 8.2e-25 87.0 0.0 1.4e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KIY52982.1 - 0.17 11.4 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) PTS_2-RNA PF01885.16 KIY52983.1 - 4.3e-65 219.2 0.0 5.2e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PTS_2-RNA PF01885.16 KIY52984.1 - 1.1e-22 81.0 0.0 1.5e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RTC4 PF14474.6 KIY52985.1 - 4.1e-23 81.8 0.0 5.4e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 RTC4-like domain SF3b1 PF08920.10 KIY52986.1 - 4.3e-21 75.6 1.0 4.3e-21 75.6 1.0 2.2 2 0 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KIY52986.1 - 1.2e-09 38.5 4.5 0.013 16.0 0.0 7.4 8 1 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 KIY52986.1 - 4.5e-09 36.6 12.1 0.0046 17.3 0.1 7.6 4 2 3 8 8 8 3 HEAT repeats HEAT PF02985.22 KIY52986.1 - 7.1e-08 32.1 13.4 0.11 12.8 0.1 9.8 12 0 0 12 12 10 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KIY52986.1 - 4.5e-07 30.4 1.3 0.93 10.1 0.0 5.5 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KIY52986.1 - 4.4e-06 25.5 1.5 0.029 13.0 0.1 3.2 2 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 KIY52986.1 - 5.2e-05 23.0 1.2 1.9 8.1 0.0 4.7 4 1 1 5 5 5 2 NUC173 domain Cnd1 PF12717.7 KIY52986.1 - 8.4e-05 22.7 10.5 0.73 9.9 0.0 6.6 8 0 0 8 8 8 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KIY52986.1 - 0.0001 22.1 0.1 1.7 8.6 0.0 5.8 5 3 1 7 7 7 1 UME (NUC010) domain CLASP_N PF12348.8 KIY52986.1 - 0.00063 19.4 2.9 0.59 9.7 0.0 3.7 3 1 0 3 3 3 2 CLASP N terminal DUF3110 PF11360.8 KIY52986.1 - 0.0067 16.6 0.1 0.021 15.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) MMS19_C PF12460.8 KIY52986.1 - 0.019 14.1 0.0 31 3.5 0.0 4.1 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal DUF1428 PF07237.11 KIY52986.1 - 0.021 15.1 1.4 4.3 7.7 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1428) ANAPC15 PF15243.6 KIY52986.1 - 0.087 13.2 1.6 13 6.2 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Dopey_N PF04118.14 KIY52986.1 - 0.11 11.6 1.0 5.8 5.9 0.0 3.4 4 0 0 4 4 4 0 Dopey, N-terminal DUF1479 PF07350.12 KIY52987.1 - 1.1e-142 475.7 0.0 1.3e-142 475.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KIY52987.1 - 0.066 13.5 0.0 0.92 9.7 0.0 2.6 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Adaptin_N PF01602.20 KIY52989.1 - 1.2e-141 472.8 7.7 1.4e-141 472.6 7.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KIY52989.1 - 2.1e-20 73.1 1.4 5e-20 71.9 1.4 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KIY52989.1 - 2.7e-08 34.0 8.0 7.6e-06 26.1 0.3 3.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY52989.1 - 0.0068 16.8 3.9 1.5 9.2 0.1 4.7 5 1 0 5 5 5 1 HEAT repeats MMS19_N PF14500.6 KIY52989.1 - 0.013 15.1 0.6 7.9 6.0 0.1 3.1 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Peptidase_M73 PF12389.8 KIY52989.1 - 0.077 12.8 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Mu-like_Pro PF10123.9 KIY52989.1 - 0.1 12.1 0.1 11 5.5 0.1 2.5 2 1 1 3 3 3 0 Mu-like prophage I protein HEAT PF02985.22 KIY52989.1 - 0.1 12.9 1.6 1.2e+02 3.4 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat RICTOR_M PF14666.6 KIY52989.1 - 0.12 12.2 0.1 0.37 10.6 0.1 1.9 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain DEC-1_N PF04625.13 KIY52989.1 - 0.52 9.3 10.7 0.93 8.4 10.7 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pet191_N PF10203.9 KIY52990.1 - 0.00026 21.2 3.9 0.00036 20.8 3.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 MTCP1 PF08991.10 KIY52990.1 - 0.00027 21.1 3.3 0.00039 20.6 3.3 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KIY52990.1 - 0.0015 18.6 6.2 0.0027 17.8 6.2 1.5 1 0 0 1 1 1 1 CHCH domain UPF0203 PF05254.12 KIY52990.1 - 0.16 12.3 6.1 0.63 10.3 6.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) LRR_8 PF13855.6 KIY52991.1 - 5.1e-18 64.6 7.3 5.6e-11 42.1 1.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIY52991.1 - 4.5e-07 30.1 2.3 0.00021 21.6 0.8 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KIY52991.1 - 0.0034 16.9 0.2 0.0076 15.8 0.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KIY52991.1 - 0.0071 16.7 0.6 28 5.8 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 KIY52991.1 - 0.06 13.4 0.8 24 5.3 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat HpcH_HpaI PF03328.14 KIY52992.1 - 2e-28 99.1 0.0 2.4e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Optomotor-blind PF11078.8 KIY52992.1 - 0.1 13.2 0.1 0.54 10.9 0.0 2.1 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region Sugar_tr PF00083.24 KIY52993.1 - 4.4e-83 279.6 17.5 5.6e-83 279.3 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY52993.1 - 1.1e-28 100.2 17.5 1.1e-28 100.2 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY52993.1 - 5.3e-06 25.1 1.5 9.8e-06 24.3 1.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fibrillarin_2 PF10113.9 KIY52993.1 - 0.032 12.9 0.2 0.047 12.3 0.2 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein OATP PF03137.20 KIY52993.1 - 1.3 7.2 9.2 1.3 7.2 1.1 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PfkB PF00294.24 KIY52994.1 - 1.3e-36 126.5 0.0 1.4e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Zds_C PF08632.10 KIY52995.1 - 9.2e-29 99.0 1.1 1.6e-28 98.2 1.1 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term MOZART1 PF12554.8 KIY52996.1 - 8.3e-24 83.1 0.6 1e-23 82.9 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Tma16 PF11176.8 KIY52997.1 - 6.9e-40 136.3 0.1 8.2e-40 136.0 0.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 FAD_binding_3 PF01494.19 KIY52998.1 - 1.2e-66 225.3 0.0 1.6e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY52998.1 - 9.1e-05 22.2 1.9 0.00062 19.4 0.2 2.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY52998.1 - 0.0002 20.7 0.2 0.013 14.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY52998.1 - 0.00021 21.5 0.1 0.0007 19.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIY52998.1 - 0.0019 17.0 0.1 0.0056 15.4 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KIY52998.1 - 0.0031 16.7 0.1 0.0051 15.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIY52998.1 - 0.0039 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KIY52998.1 - 0.0059 16.0 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY52998.1 - 0.0077 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 KIY52998.1 - 0.0091 16.5 0.2 0.62 10.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY52998.1 - 0.023 13.9 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY52998.1 - 0.038 13.1 0.1 0.092 11.8 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A CTP_transf_like PF01467.26 KIY52999.1 - 7.3e-12 45.7 0.0 9.5e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Ribonucleas_3_3 PF14622.6 KIY53000.1 - 3.4e-09 36.9 0.0 1.3e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIY53000.1 - 3.3e-06 27.7 0.0 6.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KIY53000.1 - 2.1e-05 25.1 0.0 4.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif P34-Arc PF04045.14 KIY53001.1 - 8.9e-107 356.2 0.3 1.1e-106 356.0 0.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc zf-RanBP PF00641.18 KIY53002.1 - 1.7e-08 33.6 4.6 3.3e-08 32.7 4.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KIY53002.1 - 0.023 14.1 1.1 0.059 12.8 1.1 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain AIP3 PF03915.13 KIY53004.1 - 1.3e-141 472.4 1.6 1.3e-141 472.4 1.6 1.9 2 0 0 2 2 2 1 Actin interacting protein 3 ISG65-75 PF11727.8 KIY53004.1 - 0.1 11.8 0.4 0.2 10.9 0.3 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF1664 PF07889.12 KIY53004.1 - 0.46 10.5 7.0 0.41 10.7 1.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 KIY53004.1 - 0.47 11.0 12.2 4.8 7.8 0.0 4.9 5 1 0 5 5 5 0 Syntaxin 6, N-terminal Syntaxin PF00804.25 KIY53004.1 - 0.58 9.8 6.8 5.9 6.5 0.2 3.3 2 1 1 3 3 3 0 Syntaxin OmpH PF03938.14 KIY53004.1 - 1.7 8.9 17.2 0.89 9.9 0.2 3.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 KIY53004.1 - 2.7 8.5 8.1 1.6 9.2 0.1 4.2 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KIY53004.1 - 3.4 7.7 10.6 32 4.6 0.4 4.6 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2015 PF09435.10 KIY53005.1 - 9.3e-35 118.9 0.1 1.1e-34 118.6 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Smr PF01713.21 KIY53006.1 - 9.9e-10 38.6 0.0 2.6e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Smr domain DUF2309 PF10070.9 KIY53006.1 - 0.031 12.6 0.1 0.042 12.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Ribosomal_L23 PF00276.20 KIY53007.1 - 1.8e-11 44.2 0.1 6.9e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 DHO_dh PF01180.21 KIY53009.1 - 2.4e-94 315.9 0.0 2.8e-94 315.7 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KIY53009.1 - 0.0063 15.6 0.9 0.024 13.7 1.3 1.7 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KIY53009.1 - 0.1 12.0 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Metallophos PF00149.28 KIY53010.1 - 4.5e-14 53.4 0.3 9.6e-14 52.4 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY53010.1 - 0.00016 21.9 0.1 0.0071 16.6 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Nucleopor_Nup85 PF07575.13 KIY53012.1 - 1.8e-59 201.8 0.1 1.8e-58 198.5 0.1 1.9 1 1 0 1 1 1 1 Nup85 Nucleoporin Methyltransf_24 PF13578.6 KIY53012.1 - 0.035 15.1 0.0 0.12 13.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Rhomboid PF01694.22 KIY53013.1 - 9.7e-16 58.1 8.1 1.3e-09 38.3 3.7 2.4 2 1 0 2 2 2 2 Rhomboid family Methyltransf_16 PF10294.9 KIY53014.1 - 2.1e-19 69.9 0.0 4.5e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KIY53014.1 - 0.00089 19.1 0.0 0.002 18.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Asp PF00026.23 KIY53016.1 - 6.8e-65 219.5 4.8 8.1e-65 219.3 4.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY53016.1 - 2.2e-12 47.6 3.9 2.2e-07 31.3 0.2 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIY53016.1 - 0.091 12.5 0.0 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF3157 PF11355.8 KIY53018.1 - 0.09 12.4 1.2 0.17 11.5 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) BTB PF00651.31 KIY53019.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain OAR PF03826.17 KIY53019.1 - 0.073 12.9 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 OAR domain DUF5556 PF17711.1 KIY53019.1 - 0.097 12.6 0.2 10 6.0 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5556) ACC_central PF08326.12 KIY53020.1 - 7.9e-240 798.0 0.0 1e-239 797.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KIY53020.1 - 2.3e-159 531.2 0.0 3.1e-159 530.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KIY53020.1 - 1.8e-51 174.6 0.0 4e-51 173.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIY53020.1 - 6e-28 97.6 0.1 1.3e-27 96.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIY53020.1 - 3.2e-21 75.5 0.0 5.1e-20 71.6 0.0 2.9 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIY53020.1 - 3.6e-16 58.8 0.0 7.4e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KIY53020.1 - 0.001 19.1 0.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIY53020.1 - 0.057 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KIY53020.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Fer2_4 PF13510.6 KIY53020.1 - 0.068 13.2 0.0 0.76 9.9 0.0 2.6 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Retrotrans_gag PF03732.17 KIY53021.1 - 0.00016 21.9 0.6 0.00028 21.1 0.3 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 KIY53022.1 - 4.1e-06 27.3 0.0 6.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY53022.1 - 1.7e-05 25.3 0.0 2.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KIY53022.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KIY53022.1 - 0.0018 18.0 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Sugar_tr PF00083.24 KIY53025.1 - 4.3e-90 302.7 25.0 5.2e-90 302.5 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY53025.1 - 1.9e-17 63.3 48.5 2.3e-09 36.7 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.9 KIY53025.1 - 0.76 10.0 6.3 0.26 11.5 2.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) FAD_binding_2 PF00890.24 KIY53028.1 - 3.8e-81 273.3 7.2 4.3e-81 273.1 7.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY53028.1 - 2.1e-12 47.3 4.8 7.6e-12 45.5 4.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY53028.1 - 2.2e-11 43.5 0.7 2.2e-11 43.5 0.7 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY53028.1 - 3.3e-09 36.8 3.3 5.6e-09 36.1 0.4 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIY53028.1 - 4.7e-07 29.5 2.1 1e-06 28.4 2.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIY53028.1 - 6.1e-06 25.7 0.2 7.5e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY53028.1 - 1e-05 25.0 0.2 0.0015 17.8 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY53028.1 - 1.1e-05 24.7 8.4 5.9e-05 22.3 0.6 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KIY53028.1 - 2.4e-05 23.8 0.8 0.00014 21.3 0.1 2.2 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KIY53028.1 - 6.4e-05 21.8 9.8 9.3e-05 21.3 0.4 3.1 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 KIY53028.1 - 0.00017 20.9 1.6 0.0086 15.3 0.2 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KIY53028.1 - 0.00038 19.6 0.2 0.0007 18.7 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KIY53028.1 - 0.0005 19.4 1.8 0.0006 19.2 0.3 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KIY53028.1 - 0.011 16.3 0.7 0.044 14.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KIY53028.1 - 0.14 12.4 0.2 0.82 9.9 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Pkinase PF00069.25 KIY53029.1 - 1.1e-50 172.5 0.0 1.3e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53029.1 - 9.5e-28 97.2 0.0 1.2e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY53029.1 - 0.0019 17.6 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ALS_ss_C PF10369.9 KIY53030.1 - 3.1e-20 72.1 0.1 1.8e-19 69.7 0.0 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KIY53030.1 - 2e-13 49.9 0.1 3.8e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KIY53030.1 - 7.2e-07 29.0 0.1 1.4e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KIY53030.1 - 0.05 13.6 0.5 2.3 8.2 0.2 2.5 2 0 0 2 2 2 0 ACT domain DUF150_C PF17384.2 KIY53030.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain MEIOC PF15189.6 KIY53030.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC PPI_Ypi1 PF07491.11 KIY53031.1 - 9.9e-22 76.5 13.8 2e-21 75.6 11.9 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.12 KIY53031.1 - 0.0098 14.5 6.4 0.011 14.4 6.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 KIY53031.1 - 0.081 11.2 3.2 0.085 11.1 3.2 1.0 1 0 0 1 1 1 0 CDC45-like protein COG5 PF10392.9 KIY53032.1 - 1.2e-28 99.9 3.1 2.2e-28 99.1 0.2 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KIY53032.1 - 2e-06 27.8 1.1 1.2e-05 25.3 0.1 2.7 2 1 0 2 2 2 1 Vps51/Vps67 Zw10 PF06248.13 KIY53032.1 - 6.8e-05 21.6 0.8 0.00014 20.6 0.8 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dor1 PF04124.12 KIY53032.1 - 0.04 12.6 0.7 0.091 11.4 0.7 1.5 1 0 0 1 1 1 0 Dor1-like family Occludin_ELL PF07303.13 KIY53032.1 - 0.061 14.1 0.0 0.21 12.3 0.0 1.9 1 0 0 1 1 1 0 Occludin homology domain Sec5 PF15469.6 KIY53032.1 - 0.11 12.3 0.4 0.25 11.1 0.4 1.6 1 0 0 1 1 1 0 Exocyst complex component Sec5 COG2 PF06148.11 KIY53032.1 - 0.11 12.5 2.5 0.46 10.6 1.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OPT PF03169.15 KIY53033.1 - 1.6e-180 601.8 43.9 1.8e-180 601.6 43.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TF_Zn_Ribbon PF08271.12 KIY53034.1 - 0.1 12.1 1.1 31 4.2 0.1 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding O-FucT PF10250.9 KIY53035.1 - 2.5e-09 37.3 0.1 4.7e-09 36.4 0.0 1.4 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Glyco_hydro_79C PF16862.5 KIY53036.1 - 2.8e-18 66.7 1.0 6.1e-18 65.6 0.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Asp PF00026.23 KIY53037.1 - 2.9e-46 158.3 15.5 5.7e-46 157.4 15.5 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY53037.1 - 4.4e-06 27.0 2.9 0.0012 19.1 0.2 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIY53037.1 - 0.066 13.0 0.8 8.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KIY53037.1 - 0.07 13.8 4.1 0.33 11.6 0.6 2.5 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 KIY53037.1 - 0.16 12.6 2.4 0.26 11.9 0.1 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SnoaL_2 PF12680.7 KIY53039.1 - 2.3e-07 31.4 0.0 3.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KIY53039.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Nucleos_tra2_C PF07662.13 KIY53041.1 - 3.2e-69 232.9 2.5 3.2e-69 232.9 2.5 2.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KIY53041.1 - 7.1e-20 71.4 9.4 7.1e-20 71.4 9.4 3.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KIY53041.1 - 2 8.7 24.7 0.063 13.6 7.9 3.4 3 1 0 3 3 3 0 Nucleoside recognition WD40 PF00400.32 KIY53042.1 - 3.3e-07 30.9 9.0 0.047 14.6 0.7 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat Sugar_tr PF00083.24 KIY53043.1 - 6.1e-92 308.8 19.3 7.3e-92 308.6 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY53043.1 - 1.6e-19 70.0 26.8 1.6e-19 70.0 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Myosin_head PF00063.21 KIY53045.1 - 6.4e-249 827.7 0.1 8.2e-249 827.4 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 KIY53045.1 - 5.5e-05 23.5 0.1 0.0033 17.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain Myosin_N PF02736.19 KIY53045.1 - 0.00042 20.1 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 KIY53045.1 - 0.014 15.8 0.0 0.042 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Med1 PF10744.9 KIY53046.1 - 9.5e-06 24.9 0.0 0.0031 16.6 0.1 2.3 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 KIY53047.1 - 1.2e-19 70.7 0.0 1.8e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53047.1 - 6e-09 35.6 0.0 7.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KIY53047.1 - 0.14 11.1 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KIY53047.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY53047.1 - 0.23 10.8 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prenyltransf PF01255.19 KIY53049.1 - 5.5e-51 173.2 0.0 2.6e-50 171.0 0.0 1.8 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SMC_N PF02463.19 KIY53050.1 - 1.2e-58 198.2 11.6 4.1e-58 196.4 11.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIY53050.1 - 8.1e-29 100.3 0.0 2.8e-28 98.6 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIY53050.1 - 4.2e-14 53.1 0.0 6.2e-07 29.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIY53050.1 - 1.2e-10 42.3 12.7 1.2e-10 42.3 12.7 5.9 3 2 0 4 4 4 1 AAA domain AAA_29 PF13555.6 KIY53050.1 - 1e-06 28.3 0.0 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KIY53050.1 - 0.00086 19.1 18.1 0.00086 19.1 18.1 4.3 3 2 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.6 KIY53050.1 - 0.0041 17.3 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit HrpB7 PF09486.10 KIY53050.1 - 0.0049 17.3 6.4 0.0049 17.3 6.4 7.5 4 3 2 7 7 7 3 Bacterial type III secretion protein (HrpB7) ABC_tran PF00005.27 KIY53050.1 - 0.22 12.0 0.0 0.22 12.0 0.0 5.3 4 2 0 4 4 4 0 ABC transporter TPR_2 PF07719.17 KIY53050.1 - 1.8 8.9 3.7 9.9 6.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.22 KIY53051.1 - 5.5e-17 61.2 0.3 7.8e-17 60.7 0.1 1.3 2 0 0 2 2 2 1 LSM domain Feld-I_B PF09252.10 KIY53051.1 - 0.085 12.8 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Allergen Fel d I-B chain BRICHOS PF04089.14 KIY53051.1 - 0.17 12.1 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 BRICHOS domain F-box-like PF12937.7 KIY53052.1 - 7.3e-06 25.8 0.4 7.3e-06 25.8 0.4 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY53052.1 - 0.00058 19.7 1.7 0.0049 16.7 0.3 3.0 2 0 0 2 2 2 1 F-box domain TP_methylase PF00590.20 KIY53053.1 - 6e-22 78.6 0.0 8.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA-synt_2 PF00152.20 KIY53055.1 - 5.2e-89 298.4 0.0 6.9e-89 298.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY53055.1 - 2.9e-11 43.2 0.1 1.5e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF2058 PF09831.9 KIY53055.1 - 0.0057 16.8 1.1 0.012 15.8 1.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2058) Borrelia_P83 PF05262.11 KIY53055.1 - 0.059 11.9 2.2 0.082 11.4 2.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP-synt_B PF00430.18 KIY53055.1 - 0.35 10.9 8.4 0.7 10.0 8.4 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) EMC1_C PF07774.13 KIY53056.1 - 2.8e-71 239.6 0.0 4.5e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KIY53056.1 - 2.9e-08 33.6 0.1 0.01 15.4 0.0 3.2 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KIY53056.1 - 5.8e-05 22.8 0.0 0.049 13.6 0.0 4.0 4 0 0 4 4 4 1 PQQ enzyme repeat STE3 PF02076.15 KIY53057.1 - 2.1e-104 348.8 19.0 2.3e-104 348.6 19.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF5463 PF17551.2 KIY53057.1 - 1.2 9.1 5.5 3.6 7.6 0.3 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5463) Acetyltransf_1 PF00583.25 KIY53059.1 - 2.6e-10 40.6 0.0 3.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY53059.1 - 1.1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY53059.1 - 3.4e-08 33.3 0.0 6.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KIY53059.1 - 7.4e-08 32.7 0.1 1.1e-07 32.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY53059.1 - 0.041 13.9 0.0 0.091 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RNA_pol_inhib PF16857.5 KIY53059.1 - 0.17 11.7 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase inhibitor Acyltransferase PF01553.21 KIY53060.1 - 7.5e-18 64.4 0.0 1.3e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase FA_desaturase PF00487.24 KIY53060.1 - 0.022 14.6 5.2 0.048 13.5 5.2 1.5 1 0 0 1 1 1 0 Fatty acid desaturase UCR_hinge PF02320.16 KIY53061.1 - 5.5e-23 80.9 6.6 8.1e-23 80.4 6.6 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein ORC_WH_C PF18137.1 KIY53061.1 - 0.069 13.2 0.1 0.074 13.1 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal ArgJ PF01960.18 KIY53062.1 - 3.5e-143 476.9 0.3 4e-143 476.7 0.3 1.0 1 0 0 1 1 1 1 ArgJ family F-box PF00646.33 KIY53063.1 - 0.016 15.0 2.0 0.044 13.7 2.0 1.8 1 0 0 1 1 1 0 F-box domain MMS1_N PF10433.9 KIY53064.1 - 5.7e-159 529.9 0.0 8.3e-159 529.3 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KIY53064.1 - 7.7e-94 314.6 0.0 1.1e-92 310.8 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region RVT_1 PF00078.27 KIY53068.1 - 7.8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) E2_bind PF08825.10 KIY53068.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 E2 binding domain zf-RVT PF13966.6 KIY53069.1 - 1.2e-08 35.5 3.3 1.8e-08 34.9 0.7 2.6 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase COesterase PF00135.28 KIY53070.1 - 9.3e-79 265.6 0.1 3.2e-78 263.9 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY53070.1 - 0.00032 20.6 0.2 0.0016 18.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KIY53070.1 - 0.00037 20.2 0.1 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 KIY53070.1 - 0.0011 18.5 0.1 0.0023 17.4 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBFD_NFYB_HMF PF00808.23 KIY53071.1 - 1.6e-12 47.5 1.5 2.5e-12 46.9 1.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY53071.1 - 0.0023 18.3 1.0 0.0026 18.1 1.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 KIY53071.1 - 0.022 15.0 0.5 0.027 14.7 0.5 1.2 1 0 0 1 1 1 0 CENP-W protein DUF3654 PF12376.8 KIY53071.1 - 0.093 12.9 0.3 0.32 11.2 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3654) GST_N_3 PF13417.6 KIY53072.1 - 2.9e-17 62.9 0.0 4.8e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY53072.1 - 2.6e-16 59.7 0.0 4.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY53072.1 - 1.3e-13 51.0 0.0 2.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY53072.1 - 3.3e-11 43.3 0.0 6.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY53072.1 - 2.8e-05 24.1 0.2 5.7e-05 23.1 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY53072.1 - 3.2e-05 24.0 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain motB PF17613.2 KIY53072.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Modifier of transcription DnaJ PF00226.31 KIY53073.1 - 2e-23 82.3 0.5 5.5e-23 80.9 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 KIY53073.1 - 2.1e-10 40.6 7.0 1.7e-09 37.8 0.8 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY53073.1 - 4.2e-10 39.6 0.6 4.2e-10 39.6 0.6 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIY53073.1 - 1.9e-06 28.1 5.5 0.0068 16.7 1.0 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KIY53073.1 - 6.7e-05 22.8 4.3 0.18 11.8 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KIY53073.1 - 0.00011 22.7 3.4 0.21 12.5 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY53073.1 - 0.0011 19.2 5.3 0.13 12.8 1.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type SET_assoc PF11767.8 KIY53073.1 - 0.038 13.6 0.0 0.14 11.8 0.0 2.0 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated C1_4 PF07975.12 KIY53073.1 - 0.052 13.8 0.5 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain RRM_3 PF08777.11 KIY53073.1 - 0.81 9.8 4.9 0.49 10.5 0.2 2.5 2 0 0 2 2 2 0 RNA binding motif PEPCK_ATP PF01293.20 KIY53074.1 - 6.1e-215 714.2 0.0 7.4e-215 714.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KIY53074.1 - 0.045 13.9 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 KIY53075.1 - 1.9e-152 508.2 0.0 2.2e-152 508.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KIY53075.1 - 0.024 14.8 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIY53075.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PEPCK_ATP PF01293.20 KIY53076.1 - 3.8e-215 714.9 0.0 4.5e-215 714.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KIY53076.1 - 0.025 14.7 0.0 0.08 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 KIY53077.1 - 1.5e-10 41.3 0.0 1.2e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 KIY53077.1 - 1.4e-07 31.4 0.2 0.0062 16.5 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.7 KIY53077.1 - 2.3e-06 27.9 0.0 2e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY53077.1 - 0.0014 18.6 0.1 0.069 13.1 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIY53077.1 - 0.0081 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KIY53077.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PI3_PI4_kinase PF00454.27 KIY53078.1 - 5.1e-53 180.4 0.0 1.1e-52 179.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KIY53078.1 - 4.6e-30 105.0 3.9 1.2e-29 103.6 3.9 1.8 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KIY53078.1 - 5.6e-28 96.8 0.0 2.7e-27 94.7 0.0 2.3 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 KIY53078.1 - 1.3e-07 31.3 0.1 5.1e-07 29.4 0.1 2.1 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KIY53078.1 - 0.0048 17.3 0.0 1.2 9.6 0.0 4.0 2 1 1 3 3 3 1 HEAT repeats Phage_tail_S PF05069.13 KIY53078.1 - 0.093 12.6 0.1 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 Phage virion morphogenesis family DUF3385 PF11865.8 KIY53078.1 - 0.12 12.2 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) zf-RING_UBOX PF13445.6 KIY53079.1 - 1.8e-05 24.6 7.0 1.8e-05 24.6 7.0 2.1 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY53079.1 - 0.00061 20.1 7.7 0.00061 20.1 7.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY53079.1 - 0.00079 19.2 8.0 0.00079 19.2 8.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIY53079.1 - 0.0019 18.1 1.1 0.0039 17.0 1.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KIY53079.1 - 0.0019 18.3 4.0 0.0019 18.3 4.0 2.7 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIY53079.1 - 0.0021 18.0 5.6 0.0021 18.0 5.6 2.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY53079.1 - 0.0033 17.3 7.4 0.0033 17.3 7.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY53079.1 - 0.011 15.6 10.9 0.032 14.1 5.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY53079.1 - 0.13 12.1 10.2 0.052 13.4 3.7 2.8 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIY53079.1 - 0.2 11.3 10.2 0.049 13.3 6.6 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KIY53079.1 - 0.23 11.8 9.2 0.065 13.5 4.4 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIY53079.1 - 0.33 11.0 5.3 0.4 10.8 2.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Med12 PF09497.10 KIY53080.1 - 5.3e-20 71.5 0.1 1.7e-19 69.8 0.1 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KIY53080.1 - 0.00035 19.6 0.1 0.028 13.3 0.1 2.8 1 1 1 2 2 2 1 Eukaryotic Mediator 12 subunit domain Abhydrolase_1 PF00561.20 KIY53081.1 - 6.1e-16 58.8 0.2 4.3e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY53081.1 - 7e-11 43.2 0.0 9.8e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY53081.1 - 4.3e-08 32.7 0.0 1.1e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIY53081.1 - 3.3e-06 26.7 0.0 1.1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KIY53081.1 - 1.6e-05 24.6 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KIY53081.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ndr PF03096.14 KIY53081.1 - 0.0046 15.7 0.0 0.035 12.8 0.0 1.9 1 1 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 KIY53081.1 - 0.0086 16.2 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein zf-RING-like PF08746.11 KIY53082.1 - 0.058 13.7 1.5 0.058 13.7 1.5 2.3 2 1 0 2 2 2 0 RING-like domain AT_hook PF02178.19 KIY53082.1 - 0.11 12.4 7.3 0.26 11.3 7.3 1.7 1 0 0 1 1 1 0 AT hook motif zf-C3HC4_2 PF13923.6 KIY53082.1 - 0.57 10.1 5.1 0.25 11.2 2.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Med14 PF08638.11 KIY53083.1 - 1.8e-62 210.1 1.6 2.1e-62 210.0 0.2 1.8 2 0 0 2 2 2 1 Mediator complex subunit MED14 HEAT PF02985.22 KIY53084.1 - 8e-12 44.3 1.0 0.28 11.6 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.7 KIY53084.1 - 6.9e-07 29.4 0.3 0.014 15.5 0.0 3.0 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY53084.1 - 3.5e-06 27.3 0.0 0.0017 18.7 0.0 3.5 3 1 0 3 3 3 1 HEAT repeats Pkinase PF00069.25 KIY53084.1 - 7.4e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.6 KIY53084.1 - 0.00012 22.5 0.6 0.5 10.9 0.0 4.1 3 1 1 4 4 4 2 HEAT-like repeat Pkinase_Tyr PF07714.17 KIY53084.1 - 0.00071 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Adaptin_N PF01602.20 KIY53084.1 - 0.0016 17.1 0.0 0.042 12.4 0.5 2.3 1 1 1 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.8 KIY53084.1 - 0.06 12.9 0.6 0.21 11.1 0.4 1.9 1 1 0 1 1 1 0 CLASP N terminal DASH_Dad2 PF08654.10 KIY53085.1 - 1.7e-07 31.5 0.0 2.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 Vps53_N PF04100.12 KIY53086.1 - 2.1e-90 303.4 6.3 3.3e-90 302.8 6.3 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 KIY53086.1 - 9.1e-06 25.7 6.5 4.6e-05 23.4 0.0 3.4 3 1 1 4 4 4 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 KIY53086.1 - 0.00023 20.5 6.4 0.00023 20.5 6.4 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KIY53086.1 - 0.0045 16.8 0.3 0.068 12.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) RRP36 PF06102.12 KIY53086.1 - 0.026 14.5 2.5 0.051 13.5 2.5 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 RecG_N PF17190.4 KIY53086.1 - 0.12 13.1 1.7 0.35 11.6 1.2 2.1 1 1 0 1 1 1 0 RecG N-terminal helical domain DUF1515 PF07439.11 KIY53086.1 - 0.16 12.0 2.5 0.38 10.8 2.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) FlxA PF14282.6 KIY53086.1 - 0.29 11.1 3.0 0.72 9.9 3.0 1.6 1 0 0 1 1 1 0 FlxA-like protein Tup_N PF08581.10 KIY53086.1 - 0.3 11.4 2.8 1.3 9.3 1.4 2.7 2 1 0 2 2 2 0 Tup N-terminal Atg14 PF10186.9 KIY53086.1 - 0.93 8.5 8.4 1.5 7.8 8.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KIY53086.1 - 1 9.4 4.0 1.8 8.6 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF747 PF05346.11 KIY53089.1 - 4.8e-115 384.4 5.9 5.9e-115 384.1 5.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF1463 PF07316.11 KIY53089.1 - 0.049 13.5 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) O-FucT PF10250.9 KIY53090.1 - 2.6e-05 24.1 0.0 0.0013 18.5 0.0 2.6 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase AAA PF00004.29 KIY53092.1 - 6.9e-11 42.7 0.0 1.3e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIY53092.1 - 6.1e-10 39.5 0.0 1.3e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY53092.1 - 7.1e-07 29.8 0.2 0.00033 21.1 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.12 KIY53092.1 - 0.00054 19.3 0.0 0.00093 18.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 KIY53092.1 - 0.00059 20.2 0.2 0.0021 18.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIY53092.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIY53092.1 - 0.015 15.1 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIY53092.1 - 0.016 15.1 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.14 KIY53092.1 - 0.024 13.9 0.0 0.18 11.0 0.0 2.0 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 KIY53092.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KIY53092.1 - 0.062 12.7 0.0 0.22 10.9 0.0 1.8 2 1 0 2 2 2 0 Bacterial TniB protein TrwB_AAD_bind PF10412.9 KIY53092.1 - 0.072 12.0 0.0 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.26 KIY53092.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain SMC_N PF02463.19 KIY53092.1 - 0.11 11.9 0.1 14 5.0 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KIY53092.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 KIY53092.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 KIY53092.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KIY53092.1 - 0.17 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KIY53092.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 NTPase GCP_C_terminal PF04130.13 KIY53093.1 - 1.6e-49 169.1 1.6 4.3e-49 167.6 0.2 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KIY53093.1 - 4.4e-14 52.8 0.1 1.1e-13 51.5 0.1 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF2367 PF10164.9 KIY53094.1 - 1.2e-06 29.0 2.7 1.5e-06 28.6 2.7 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Methyltransf_25 PF13649.6 KIY53095.1 - 4.9e-13 49.6 0.0 1.3e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY53095.1 - 1.1e-11 44.7 0.1 3.5e-11 43.1 0.1 1.7 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KIY53095.1 - 2.9e-11 43.3 0.0 4.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KIY53095.1 - 2.7e-10 40.7 0.0 7.4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KIY53095.1 - 2.9e-08 33.0 0.0 4.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 KIY53095.1 - 1.8e-07 31.2 0.0 7.4e-07 29.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY53095.1 - 7.4e-07 29.8 0.1 1.8e-06 28.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 KIY53095.1 - 2.3e-06 27.1 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 KIY53095.1 - 4.6e-06 26.2 0.2 1.6e-05 24.4 0.2 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 KIY53095.1 - 7.9e-06 25.5 0.1 1.4e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KIY53095.1 - 0.00022 21.0 0.1 0.00041 20.2 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KIY53095.1 - 0.00035 20.0 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KIY53095.1 - 0.002 18.1 0.1 0.0033 17.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KIY53095.1 - 0.0024 18.0 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KIY53095.1 - 0.0057 16.4 0.1 0.0089 15.8 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KIY53095.1 - 0.0062 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 KIY53095.1 - 0.017 16.1 0.0 0.047 14.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KIY53095.1 - 0.027 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1194 PF06707.11 KIY53095.1 - 0.031 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Methyltransf_4 PF02390.17 KIY53095.1 - 0.1 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase F-box PF00646.33 KIY53096.1 - 0.0056 16.5 1.3 0.011 15.6 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KIY53096.1 - 0.048 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KIY53096.1 - 0.088 12.7 0.1 0.26 11.2 0.1 1.9 1 0 0 1 1 1 0 F-box-like Na_K-ATPase PF00287.18 KIY53097.1 - 0.0096 15.1 3.8 0.012 14.8 3.8 1.2 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain SUR7 PF06687.12 KIY53098.1 - 2.1e-07 30.8 13.4 1.3e-06 28.2 13.4 1.9 1 1 0 1 1 1 1 SUR7/PalI family Tetraspanin PF00335.20 KIY53098.1 - 0.0039 16.9 0.9 0.0039 16.9 0.9 2.3 1 1 1 2 2 2 1 Tetraspanin family Claudin_3 PF06653.11 KIY53098.1 - 0.021 14.8 6.5 0.063 13.2 1.8 2.2 2 1 0 2 2 2 0 Tight junction protein, Claudin-like Vut_1 PF02592.15 KIY53098.1 - 0.1 12.9 4.4 0.049 13.9 1.5 1.8 2 0 0 2 2 2 0 Putative vitamin uptake transporter p450 PF00067.22 KIY53099.1 - 6.2e-05 21.9 0.0 6.2e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C15 PF01470.17 KIY53100.1 - 2.3e-13 50.8 0.0 9e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase zf-CCHC PF00098.23 KIY53101.1 - 7.2e-12 44.8 25.0 0.00044 20.2 1.9 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KIY53101.1 - 3.4e-05 23.6 21.1 0.001 18.8 0.4 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 KIY53101.1 - 0.21 11.4 22.5 1.6 8.5 0.5 4.3 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_5 PF14787.6 KIY53101.1 - 3 7.6 25.7 0.51 10.1 3.0 3.9 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger Herpes_DNAp_acc PF04929.12 KIY53102.1 - 1.8 7.4 6.8 2.5 7.0 6.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RrnaAD PF00398.20 KIY53104.1 - 1.5e-20 73.4 0.0 5e-14 52.0 0.0 2.0 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase HTH_35 PF13693.6 KIY53104.1 - 0.08 13.0 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mcl1_mid PF12341.8 KIY53105.1 - 1.3e-71 241.4 0.0 3.7e-71 239.9 0.0 1.8 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KIY53105.1 - 3.9e-15 56.0 10.4 0.00057 20.6 0.3 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY53105.1 - 4.7e-09 36.4 0.0 0.56 10.6 0.0 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG PF13634.6 KIY53105.1 - 0.35 11.7 4.9 0.84 10.5 4.9 1.7 1 0 0 1 1 1 0 Nucleoporin FG repeat region CPSF73-100_C PF11718.8 KIY53106.1 - 1e-59 201.8 0.0 1.5e-59 201.2 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KIY53106.1 - 1.2e-28 99.6 0.0 3.9e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KIY53106.1 - 1.2e-19 70.6 0.0 3.3e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY53106.1 - 1.6e-15 57.7 1.3 1.2e-14 54.7 1.3 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KIY53106.1 - 4.5e-15 55.3 0.2 8.5e-15 54.4 0.2 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 KIY53106.1 - 3.1e-07 30.4 0.7 2e-06 27.8 0.1 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KIY53106.1 - 4.9e-07 29.5 1.5 1.3e-06 28.1 0.4 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DNA_methylase PF00145.17 KIY53107.1 - 2.5e-14 53.4 0.0 2.6e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNA_methylase PF00145.17 KIY53108.1 - 9.9e-12 44.8 0.1 3.3e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 KIY53108.1 - 4.8e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 KIY53108.1 - 6.8e-06 25.9 0.0 0.0012 18.7 0.0 2.7 3 0 0 3 3 3 2 BAH domain Aminotran_3 PF00202.21 KIY53110.1 - 1.1e-74 251.5 0.0 1.4e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III G_glu_transpept PF01019.21 KIY53111.1 - 2.9e-154 514.7 0.0 3.3e-154 514.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Peptidase_A22B PF04258.13 KIY53112.1 - 6.2e-72 242.5 9.6 7.6e-72 242.2 9.6 1.0 1 0 0 1 1 1 1 Signal peptide peptidase GATA PF00320.27 KIY53113.1 - 1e-18 66.6 2.6 2.2e-18 65.6 2.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KIY53113.1 - 5.4e-12 45.3 1.2 1.4e-11 44.0 1.2 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PH_9 PF15410.6 KIY53114.1 - 1.7e-28 99.4 0.0 3.9e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 KIY53114.1 - 2.4e-27 95.8 0.3 8.8e-27 94.0 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 KIY53114.1 - 0.00026 21.5 0.0 0.00063 20.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Glyco_hydro_76 PF03663.14 KIY53115.1 - 2.9e-28 99.4 20.6 3.6e-28 99.1 20.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 NAPRTase PF04095.16 KIY53116.1 - 2.6e-58 197.5 0.1 3.3e-58 197.1 0.1 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KIY53116.1 - 1.4e-35 122.4 0.1 2.1e-35 121.9 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain MFS_1 PF07690.16 KIY53118.1 - 2.2e-38 132.1 36.9 2.2e-38 132.1 36.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY53118.1 - 1.6e-06 27.3 32.9 2.2e-05 23.5 32.9 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRAP-gamma PF07074.12 KIY53118.1 - 0.11 12.0 0.8 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) ORC6 PF05460.13 KIY53119.1 - 0.88 8.8 7.8 1.7 7.8 7.8 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Med3 PF11593.8 KIY53119.1 - 3.3 6.8 11.5 4.6 6.3 11.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4551 PF15087.6 KIY53119.1 - 4.5 6.0 9.4 5.6 5.7 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CytochromB561_N PF09786.9 KIY53119.1 - 6.4 5.7 16.3 8.7 5.2 16.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Choline_transpo PF04515.12 KIY53121.1 - 1.8e-76 257.5 18.0 1.8e-76 257.5 18.0 2.4 2 1 0 2 2 2 1 Plasma-membrane choline transporter TMEMspv1-c74-12 PF11044.8 KIY53121.1 - 6.4 6.8 11.6 6.4 6.9 2.5 2.9 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein SNF2_N PF00176.23 KIY53122.1 - 1.2e-63 215.0 0.1 3.9e-63 213.3 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY53122.1 - 3.6e-18 65.9 0.0 1.3e-16 60.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY53122.1 - 1e-07 32.1 0.0 2.9e-06 27.4 0.0 3.3 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIY53122.1 - 9.8e-06 24.9 0.0 2.6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Glyco_trans_4_5 PF16994.5 KIY53122.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl-transferase family 4 SWI2_SNF2 PF18766.1 KIY53122.1 - 0.088 12.5 0.0 3 7.4 0.0 3.3 4 0 0 4 4 4 0 SWI2/SNF2 ATPase Kazal_3 PF18434.1 KIY53122.1 - 0.13 12.0 0.0 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain FLILHELTA PF10306.9 KIY53124.1 - 5.6e-08 33.1 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KIY53124.1 - 0.002 18.6 0.2 0.0045 17.5 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L35Ae PF01247.18 KIY53125.1 - 9e-44 147.6 0.3 1e-43 147.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KIY53125.1 - 0.00054 20.1 0.0 1.4 9.2 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Calici_MSP PF05752.11 KIY53125.1 - 0.065 13.1 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein HMG_box PF00505.19 KIY53127.1 - 2.4e-18 66.3 1.1 4.2e-18 65.5 1.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY53127.1 - 7.2e-14 52.1 0.4 1.6e-13 51.0 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain PNP_UDP_1 PF01048.20 KIY53128.1 - 2.8e-26 92.2 0.0 4e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily zf-C2H2 PF00096.26 KIY53129.1 - 0.0056 17.1 3.6 0.011 16.1 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 KIY53129.1 - 0.23 11.9 1.4 0.53 10.8 1.4 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Zn_clus PF00172.18 KIY53130.1 - 3.1e-08 33.6 10.9 4.9e-08 33.0 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KIY53131.1 - 3.2e-15 55.9 1.1 3.5e-15 55.7 1.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_90 PF05686.12 KIY53132.1 - 9e-16 57.8 0.1 2e-15 56.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 90 PhoD_N PF16655.5 KIY53132.1 - 0.026 15.1 0.1 1.7 9.2 0.1 2.7 3 0 0 3 3 3 0 PhoD-like phosphatase, N-terminal domain Pkinase PF00069.25 KIY53133.1 - 1.9e-68 230.7 0.0 2.6e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53133.1 - 4.2e-34 118.0 0.0 6.5e-33 114.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY53133.1 - 1.8e-05 24.2 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.9 KIY53133.1 - 0.00028 20.5 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KIY53133.1 - 0.001 18.5 0.0 0.0076 15.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY53133.1 - 0.042 12.6 0.4 0.07 11.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase SET PF00856.28 KIY53134.1 - 2.1e-12 47.8 0.1 2.2e-12 47.7 0.1 1.0 1 0 0 1 1 1 1 SET domain APG12 PF04110.13 KIY53136.1 - 3.2e-30 104.4 0.0 3.8e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KIY53136.1 - 0.041 14.1 0.0 0.048 13.9 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like OKR_DC_1 PF01276.20 KIY53137.1 - 0.043 12.5 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain HGTP_anticodon PF03129.20 KIY53138.1 - 9.9e-22 76.9 0.0 2.4e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIY53138.1 - 2.6e-11 43.8 0.0 4.9e-10 39.7 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) SasG_E PF17041.5 KIY53138.1 - 0.0081 16.1 1.2 0.021 14.8 0.0 2.3 3 0 0 3 3 3 1 E domain Bestrophin PF01062.21 KIY53139.1 - 4.4e-33 114.9 2.4 3.7e-23 82.4 0.0 2.4 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Na_Ca_ex PF01699.24 KIY53140.1 - 2.6e-12 46.9 7.0 3e-12 46.7 7.0 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein FtsL PF04999.13 KIY53140.1 - 0.024 14.6 0.2 0.053 13.5 0.2 1.5 1 0 0 1 1 1 0 Cell division protein FtsL HILPDA PF15220.6 KIY53140.1 - 0.12 12.5 1.1 0.23 11.6 1.1 1.4 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated Syndecan PF01034.20 KIY53140.1 - 0.17 11.8 2.7 0.34 10.9 0.2 2.1 2 0 0 2 2 2 0 Syndecan domain Lipase_3 PF01764.25 KIY53141.1 - 1.4e-26 93.1 0.0 2.1e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KIY53141.1 - 0.012 15.4 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 KIY53141.1 - 0.056 13.4 0.1 0.086 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Paxillin PF03535.13 KIY53141.1 - 0.067 13.1 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Paxillin family Abhydrolase_6 PF12697.7 KIY53141.1 - 0.1 13.2 1.3 0.14 12.7 0.3 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.14 KIY53141.1 - 0.18 11.3 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Sec63 PF02889.16 KIY53142.1 - 3.4e-145 481.9 0.2 1.1e-72 244.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KIY53142.1 - 2.5e-47 160.9 0.3 1.7e-25 89.8 0.0 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KIY53142.1 - 7.9e-35 119.4 0.0 3.5e-34 117.3 0.0 2.2 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KIY53142.1 - 2.5e-23 83.0 0.0 6.8e-14 52.2 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY53142.1 - 1.3e-14 54.4 0.0 1e-08 35.5 0.0 4.1 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIY53142.1 - 3.7e-06 27.2 0.7 0.013 15.7 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KIY53142.1 - 0.00016 21.4 0.0 0.13 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KIY53142.1 - 0.0066 15.9 0.1 0.44 10.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 KIY53142.1 - 0.014 14.5 0.0 0.57 9.2 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein NuiA PF07924.11 KIY53142.1 - 0.11 12.9 0.4 0.31 11.4 0.1 1.9 2 0 0 2 2 1 0 Nuclease A inhibitor-like protein Peptidase_C39 PF03412.15 KIY53142.1 - 0.13 12.1 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase C39 family Glyco_hydro_61 PF03443.14 KIY53143.1 - 7.7e-50 169.7 0.0 9.3e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 KIY53144.1 - 4e-38 131.3 36.8 4e-38 131.3 36.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY53144.1 - 3.2e-05 22.6 3.1 3.2e-05 22.6 3.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Acetyltransf_3 PF13302.7 KIY53145.1 - 3e-19 70.1 0.0 3.9e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIY53145.1 - 0.0045 16.7 1.5 17 5.0 0.6 3.1 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY53145.1 - 0.0072 16.3 0.0 0.078 12.9 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KIY53145.1 - 0.0091 16.2 0.0 3.3 8.0 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY53145.1 - 0.16 11.9 0.0 6.7 6.7 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF1242 PF06842.12 KIY53146.1 - 1.5e-17 63.1 2.5 2e-17 62.7 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Epimerase PF01370.21 KIY53149.1 - 3.3e-18 66.1 0.0 4.7e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY53149.1 - 1.1e-11 44.2 0.0 2.5e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIY53149.1 - 3.9e-11 43.2 0.0 6.5e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIY53149.1 - 3.4e-10 39.5 0.0 1.7e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIY53149.1 - 5e-05 22.9 0.0 0.00032 20.2 0.0 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIY53149.1 - 6.7e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIY53149.1 - 0.069 12.7 0.3 0.14 11.7 0.3 1.5 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 KIY53149.1 - 0.08 12.4 0.0 0.24 10.9 0.0 1.9 2 1 0 2 2 2 0 short chain dehydrogenase ETF_QO PF05187.13 KIY53150.1 - 5.3e-38 129.3 0.2 9.7e-38 128.5 0.2 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Thi4 PF01946.17 KIY53150.1 - 7.8e-08 31.8 0.0 0.00022 20.5 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KIY53150.1 - 3.2e-07 30.5 0.0 8.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY53150.1 - 8.1e-07 28.5 0.2 9.8e-05 21.6 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIY53150.1 - 1.3e-06 28.3 0.2 6.5e-06 26.0 0.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY53150.1 - 3.9e-05 23.0 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY53150.1 - 0.00012 21.5 0.1 0.00018 20.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIY53150.1 - 0.00023 20.0 0.2 0.00034 19.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KIY53150.1 - 0.00032 20.0 0.1 0.0005 19.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY53150.1 - 0.00047 20.2 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_7 PF12838.7 KIY53150.1 - 0.0023 18.5 0.9 0.007 16.9 0.9 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 KIY53150.1 - 0.0062 15.6 0.2 0.0093 15.1 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KIY53150.1 - 0.063 12.6 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KIY53150.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_10 PF13237.6 KIY53150.1 - 0.14 12.3 0.9 0.31 11.2 0.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 KIY53150.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_6 PF12837.7 KIY53150.1 - 1.7 8.8 4.8 1.5 9.0 1.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain PP2C PF00481.21 KIY53152.1 - 1.4e-23 83.9 0.0 6.9e-22 78.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIY53152.1 - 2.8e-10 40.2 0.0 4.8e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KIY53152.1 - 0.00013 21.9 0.2 0.15 11.9 0.0 2.7 2 1 1 3 3 3 2 Stage II sporulation protein E (SpoIIE) p450 PF00067.22 KIY53153.1 - 1.1e-61 209.0 0.0 1.6e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KIY53154.1 - 3.4e-37 128.2 38.1 3.4e-37 128.2 38.1 1.8 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY53154.1 - 8.7e-05 21.1 7.7 0.00016 20.3 7.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_C54 PF03416.19 KIY53156.1 - 1.5e-97 326.3 0.0 2e-97 325.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Aldedh PF00171.22 KIY53157.1 - 5.6e-183 608.7 0.1 6.4e-183 608.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIY53157.1 - 0.0041 16.2 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) SRAP PF02586.14 KIY53158.1 - 3.4e-68 229.5 0.0 3.9e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) AMP-binding PF00501.28 KIY53159.1 - 2.6e-59 200.9 0.0 8.2e-59 199.3 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY53159.1 - 1.2e-16 61.5 0.1 3.5e-16 60.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rotamase PF00639.21 KIY53160.1 - 7.1e-21 75.0 0.0 9.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KIY53160.1 - 2.5e-19 69.9 0.0 3.2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KIY53160.1 - 1.2e-05 25.3 0.3 6.3e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KIY53160.1 - 0.0078 17.0 0.0 0.012 16.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain UCH PF00443.29 KIY53161.1 - 1.3e-37 129.7 0.0 2.7e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIY53161.1 - 8e-25 86.9 10.0 5.9e-20 71.4 1.5 2.8 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KIY53161.1 - 3.8e-24 84.2 1.0 3.3e-11 42.9 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 KIY53161.1 - 1.9e-23 82.0 1.5 3.5e-22 77.9 0.2 2.4 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 KIY53161.1 - 1.4e-17 64.3 0.9 3.7e-16 59.6 0.0 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-C2HE PF16278.5 KIY53161.1 - 0.0036 17.7 1.1 1 9.8 0.0 3.5 3 0 0 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger CUE PF02845.16 KIY53161.1 - 0.05 13.3 0.0 8.4 6.2 0.0 3.1 3 0 0 3 3 3 0 CUE domain Ribosomal_L5_C PF00673.21 KIY53161.1 - 0.17 12.1 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 ribosomal L5P family C-terminus HSP70 PF00012.20 KIY53162.1 - 2.5e-62 210.9 0.2 3.4e-62 210.5 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY53162.1 - 2.2e-05 23.4 0.2 0.00028 19.8 0.2 2.3 1 1 0 1 1 1 1 MreB/Mbl protein ECH_1 PF00378.20 KIY53163.1 - 2.3e-36 125.4 0.0 3.7e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY53163.1 - 2.3e-19 70.1 0.0 5.2e-19 68.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase GATA PF00320.27 KIY53166.1 - 3.5e-26 90.5 17.3 2.5e-15 55.8 2.2 2.2 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 KIY53166.1 - 1.8e-05 24.8 2.7 0.011 15.8 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain DZR PF12773.7 KIY53166.1 - 0.00042 20.3 4.9 0.024 14.6 5.5 2.8 1 1 1 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KIY53166.1 - 0.0012 18.3 6.8 0.013 15.0 0.8 2.5 2 1 0 2 2 2 2 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 KIY53166.1 - 0.0067 16.7 0.9 0.0067 16.7 0.9 2.4 2 1 0 2 2 2 1 zinc-ribbon eIF-5_eIF-2B PF01873.17 KIY53166.1 - 0.0085 16.0 5.3 0.91 9.4 0.4 2.2 2 0 0 2 2 2 2 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 KIY53166.1 - 0.012 15.8 7.7 0.071 13.3 1.7 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-Sec23_Sec24 PF04810.15 KIY53166.1 - 0.015 15.4 0.8 0.015 15.4 0.8 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Elf1 PF05129.13 KIY53166.1 - 0.018 15.1 4.3 0.14 12.2 0.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RRN7 PF11781.8 KIY53166.1 - 0.024 14.3 4.9 0.024 14.3 4.9 3.8 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OrfB_Zn_ribbon PF07282.11 KIY53166.1 - 0.051 13.5 10.0 0.99 9.4 1.0 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Ins145_P3_rec PF08709.11 KIY53166.1 - 0.16 11.2 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Rubredoxin_2 PF18073.1 KIY53166.1 - 3.4 7.5 13.9 9.8 6.0 0.2 4.1 4 0 0 4 4 4 0 Rubredoxin metal binding domain zf-C2H2_3 PF13878.6 KIY53166.1 - 3.6 7.5 11.9 4.8 7.1 0.2 3.8 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-ribbon_3 PF13248.6 KIY53166.1 - 3.9 7.0 14.2 10 5.7 0.2 3.9 3 1 0 3 3 3 0 zinc-ribbon domain C1_2 PF03107.16 KIY53166.1 - 5.3 7.4 12.1 3.2 8.2 1.9 2.9 3 1 0 3 3 3 0 C1 domain zf-FCS PF06467.14 KIY53166.1 - 9.8 6.2 12.8 6.7 6.8 0.2 3.8 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif NAP PF00956.18 KIY53167.1 - 8.3e-62 208.8 1.1 1.4e-60 204.7 1.1 2.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Thaumatin PF00314.17 KIY53168.1 - 6.9e-24 84.7 0.4 6.9e-24 84.7 0.4 1.9 1 1 1 2 2 2 1 Thaumatin family DEAD PF00270.29 KIY53171.1 - 3.4e-18 66.0 0.2 1.5e-13 50.9 0.2 3.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY53171.1 - 1.1e-11 45.1 0.0 1.4e-10 41.5 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Peptidase_A4 PF01828.17 KIY53173.1 - 7.6e-38 130.1 13.1 6.5e-36 123.8 13.1 2.0 1 1 0 1 1 1 1 Peptidase A4 family Homeobox_KN PF05920.11 KIY53175.1 - 7.2e-18 64.2 0.1 7.2e-18 64.2 0.1 3.1 4 0 0 4 4 4 1 Homeobox KN domain Homeodomain PF00046.29 KIY53175.1 - 2.9e-05 23.8 0.1 5.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 KIY53179.1 - 5.3e-19 68.6 0.0 6.6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53179.1 - 2.7e-06 26.9 0.0 3.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY53179.1 - 2.1e-05 24.6 0.1 4.6e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY53179.1 - 2.4e-05 23.3 0.0 2.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KIY53179.1 - 0.0025 17.5 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY53179.1 - 0.0047 16.3 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY53179.1 - 0.0089 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIY53179.1 - 0.016 14.8 0.0 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Asparaginase_II PF06089.12 KIY53180.1 - 0.084 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 L-asparaginase II DNA_ligase_OB_2 PF14743.6 KIY53182.1 - 2.1e-28 98.1 0.5 4.4e-28 97.1 0.5 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 KIY53182.1 - 1.3e-12 47.8 0.0 3.5e-12 46.4 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KIY53182.1 - 0.00045 20.6 0.0 0.0038 17.6 0.0 2.1 1 1 0 1 1 1 1 RNA ligase PBP1_TM PF14812.6 KIY53182.1 - 0.019 15.3 0.9 0.036 14.5 0.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Epimerase PF01370.21 KIY53183.1 - 2e-07 30.7 0.0 3.7e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY53183.1 - 0.0011 18.0 0.0 0.055 12.5 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIY53183.1 - 0.0012 18.7 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIY53183.1 - 0.0045 16.1 0.0 0.28 10.2 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain Rossmann-like PF10727.9 KIY53183.1 - 0.0056 16.5 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 Rossmann-like domain NAD_binding_2 PF03446.15 KIY53183.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 KIY53183.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KIY53183.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KIY53183.1 - 0.042 13.2 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase UDPG_MGDP_dh_N PF03721.14 KIY53183.1 - 0.044 13.4 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.25 KIY53183.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DIOX_N PF14226.6 KIY53185.1 - 1.1e-14 55.2 0.0 2.1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY53185.1 - 1.2e-14 54.6 0.0 2.3e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kelch_1 PF01344.25 KIY53185.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Glyco_hydro_92 PF07971.12 KIY53187.1 - 8.5e-122 407.4 0.0 1e-121 407.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIY53187.1 - 3.4e-42 145.0 0.0 4.8e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain STE2 PF02116.15 KIY53188.1 - 0.00018 20.9 9.7 0.00018 20.9 9.7 2.7 2 1 0 2 2 2 1 Fungal pheromone mating factor STE2 GPCR Rab5ip PF07019.12 KIY53188.1 - 0.36 11.4 0.2 0.36 11.4 0.2 3.5 3 2 1 4 4 4 0 Rab5-interacting protein (Rab5ip) Phage_holin_2_3 PF16080.5 KIY53188.1 - 1.5 8.6 5.5 0.29 10.9 0.6 2.3 2 0 0 2 2 2 0 Bacteriophage holin family HP1 SUR7 PF06687.12 KIY53188.1 - 3.1 7.4 17.1 5.6 6.5 5.8 2.6 2 1 0 2 2 2 0 SUR7/PalI family MFS_1 PF07690.16 KIY53189.1 - 1.1e-18 67.3 20.2 1.5e-18 66.8 20.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3721 PF12518.8 KIY53189.1 - 1.3 9.0 2.6 5.3 7.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function Perilipin PF03036.16 KIY53190.1 - 0.028 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Perilipin family Phage_holin_7_1 PF16081.5 KIY53190.1 - 0.14 12.3 4.2 0.11 12.7 1.5 2.1 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family STE3 PF02076.15 KIY53191.1 - 3.3e-34 118.4 13.7 3.3e-34 118.4 13.7 1.3 1 1 0 1 1 1 1 Pheromone A receptor 4HBT_3 PF13622.6 KIY53192.1 - 1e-55 189.7 0.5 1.3e-55 189.4 0.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KIY53192.1 - 7e-20 71.2 0.0 3.9e-16 59.1 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase DUF5555 PF17710.1 KIY53192.1 - 0.056 13.0 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5555) p450 PF00067.22 KIY53193.1 - 4.9e-72 243.2 0.0 1.6e-71 241.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DDE_Tnp_1_assoc PF13808.6 KIY53194.1 - 0.035 14.1 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-associated Pkinase_Tyr PF07714.17 KIY53195.1 - 9.8e-49 166.0 0.0 1.4e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY53195.1 - 4.2e-37 127.9 0.0 2.5e-27 95.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KIY53195.1 - 0.0014 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY53195.1 - 0.0026 17.4 0.0 0.0064 16.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY53195.1 - 0.0054 16.7 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY53195.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ABATE PF07336.11 KIY53196.1 - 0.057 14.1 1.1 0.075 13.7 1.1 1.3 1 1 0 1 1 1 0 Putative stress-induced transcription regulator KDZ PF18758.1 KIY53197.1 - 7.9e-38 130.3 0.1 1.3e-37 129.6 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF1442 PF07279.11 KIY53197.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) SH3BP5 PF05276.14 KIY53197.1 - 0.5 10.1 5.4 0.29 10.9 3.3 1.6 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Occludin_ELL PF07303.13 KIY53197.1 - 0.74 10.6 5.6 5.4 7.8 4.3 2.5 2 1 1 3 3 3 0 Occludin homology domain KDZ PF18758.1 KIY53198.1 - 2.7e-21 76.2 0.0 4.6e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY53198.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY53198.1 - 0.078 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases DUF3106 PF11304.8 KIY53198.1 - 4.6 7.8 10.2 1.1 9.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) LPD38 PF18857.1 KIY53199.1 - 0.18 11.9 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 Filament PF00038.21 KIY53200.1 - 0.028 14.0 0.8 0.042 13.4 0.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein HALZ PF02183.18 KIY53200.1 - 0.35 11.1 5.9 2 8.7 0.6 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 KIY53200.1 - 2.5 8.8 6.0 4.6 7.9 0.2 2.8 2 1 1 3 3 3 0 Initiation control protein YabA HMG_box_2 PF09011.10 KIY53201.1 - 0.00079 20.0 0.2 0.00079 20.0 0.2 3.4 4 0 0 4 4 4 1 HMG-box domain DUF1178 PF06676.11 KIY53201.1 - 0.01 16.2 0.0 0.01 16.2 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1178) Spidroin_N PF16763.5 KIY53201.1 - 0.18 11.8 0.9 0.39 10.7 0.2 1.9 3 0 0 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term STE3 PF02076.15 KIY53203.1 - 3.9e-26 91.9 11.8 7.6e-26 91.0 11.8 1.4 1 1 0 1 1 1 1 Pheromone A receptor MARVEL PF01284.23 KIY53203.1 - 5.4 7.0 11.7 31 4.6 1.2 2.6 1 1 1 2 2 2 0 Membrane-associating domain Pyr_redox_2 PF07992.14 KIY53204.1 - 6.1e-06 25.7 0.1 4.6e-05 22.8 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY53204.1 - 0.14 12.1 0.0 0.94 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF1758 PF05585.12 KIY53204.1 - 0.23 11.2 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) p450 PF00067.22 KIY53206.1 - 7.2e-65 219.5 0.0 4.3e-64 217.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF3533 PF12051.8 KIY53209.1 - 4.4e-86 289.2 17.2 5.2e-86 288.9 17.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Glyco_hydro_16 PF00722.21 KIY53210.1 - 5.5e-18 65.0 1.3 9.2e-18 64.3 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 LRR_4 PF12799.7 KIY53211.1 - 7e-25 86.7 24.0 6.1e-06 26.5 0.0 8.5 6 1 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY53211.1 - 4.9e-16 58.2 29.4 5.9e-06 26.0 5.8 6.3 5 1 4 9 9 9 6 Leucine rich repeat LRR_9 PF14580.6 KIY53211.1 - 9.3e-08 31.8 9.0 0.24 10.9 1.1 4.9 3 1 2 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 KIY53211.1 - 0.013 15.9 28.7 17 6.5 0.4 9.1 9 2 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 KIY53211.1 - 0.44 10.7 21.9 12 6.2 0.3 8.5 9 0 0 9 9 9 0 Leucine Rich repeat MFS_1 PF07690.16 KIY53212.1 - 4.3e-18 65.4 22.1 5.7e-18 65.0 22.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cellulase PF00150.18 KIY53213.1 - 9.2e-09 35.1 0.0 1.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.8 KIY53213.1 - 0.095 13.2 0.5 0.24 11.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) p450 PF00067.22 KIY53214.1 - 1.8e-41 142.4 0.0 9e-20 70.8 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KIY53215.1 - 0.0039 16.0 0.0 0.0095 14.7 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 DAG1 PF05454.11 KIY53215.1 - 0.17 11.2 0.1 0.26 10.6 0.1 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) bZIP_2 PF07716.15 KIY53218.1 - 2e-05 24.5 9.0 2e-05 24.5 9.0 4.3 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY53218.1 - 2.4 8.3 27.7 0.039 14.1 10.3 3.7 3 1 1 4 4 4 0 bZIP transcription factor F-box PF00646.33 KIY53219.1 - 0.0032 17.3 0.1 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 F-box domain Glyco_hydro_3_C PF01915.22 KIY53221.1 - 8e-51 172.9 0.1 1.2e-50 172.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY53221.1 - 8.2e-36 124.0 0.0 3e-35 122.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY53221.1 - 1.2e-18 66.9 0.0 2.4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.25 KIY53222.1 - 2.6e-07 30.3 0.0 2.1e-05 24.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53222.1 - 0.00046 19.6 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase OmpA PF00691.20 KIY53223.1 - 0.018 15.4 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 OmpA family DapB_N PF01113.20 KIY53223.1 - 0.057 13.5 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus p450 PF00067.22 KIY53224.1 - 1.3e-07 30.7 0.0 3e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ribonuc_red_lgN PF00317.21 KIY53224.1 - 0.16 12.0 0.0 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain Mito_carr PF00153.27 KIY53225.1 - 4e-15 55.5 0.1 4.4e-15 55.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Ribosomal_S13_N PF08069.12 KIY53226.1 - 6.4e-31 106.2 0.1 1.3e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KIY53226.1 - 3.4e-15 56.0 0.2 5e-15 55.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 HTH_32 PF13565.6 KIY53226.1 - 0.055 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_hydro_71 PF03659.14 KIY53227.1 - 2.4e-93 313.0 11.2 2.4e-93 313.0 11.2 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Pkinase PF00069.25 KIY53228.1 - 9.8e-05 21.8 0.0 0.0001 21.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KIY53229.1 - 3.3e-06 26.7 0.0 0.0003 20.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53229.1 - 0.0016 17.8 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KIY53230.1 - 4e-05 23.1 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53230.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 KIY53230.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_3 PF07859.13 KIY53231.1 - 1e-38 133.3 0.0 1.2e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY53231.1 - 1.6e-06 27.3 0.0 3.1e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Sacchrp_dh_NADP PF03435.18 KIY53232.1 - 6.5e-20 71.7 0.1 1.4e-19 70.6 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KIY53232.1 - 5.8e-05 23.1 0.0 8.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY53232.1 - 0.00081 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KIY53232.1 - 0.0019 18.7 0.0 0.005 17.3 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KIY53232.1 - 0.005 15.9 0.0 0.009 15.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIY53232.1 - 0.0092 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIY53232.1 - 0.018 15.0 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 KR domain zf-C2H2_jaz PF12171.8 KIY53233.1 - 3e-06 27.4 7.6 4.9e-06 26.7 7.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding UPAR_LY6_2 PF16975.5 KIY53233.1 - 0.051 13.8 0.3 0.07 13.3 0.3 1.2 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 zf-C2H2_2 PF12756.7 KIY53233.1 - 0.3 11.4 5.4 0.19 12.1 3.8 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) HIT PF01230.23 KIY53234.1 - 2.3e-21 76.3 0.2 4.3e-21 75.5 0.2 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KIY53234.1 - 7.5e-14 52.2 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIY53234.1 - 1e-05 25.4 0.3 1.8e-05 24.6 0.3 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Glyco_hydro_61 PF03443.14 KIY53235.1 - 1.9e-46 158.6 0.0 2.3e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SET PF00856.28 KIY53236.1 - 2.3e-10 41.1 0.7 7.7e-10 39.4 0.7 1.8 1 1 0 1 1 1 1 SET domain E1-E2_ATPase PF00122.20 KIY53238.1 - 8.7e-49 165.5 0.1 8.7e-49 165.5 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIY53238.1 - 4.5e-19 69.6 0.1 1.2e-18 68.2 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIY53238.1 - 1.1e-13 50.6 0.1 3.5e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY53238.1 - 0.00031 20.6 0.6 0.001 18.8 0.0 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY53238.1 - 0.06 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2034 PF10356.9 KIY53239.1 - 9.9e-16 57.7 0.4 2.1e-11 43.6 0.5 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KIY53239.1 - 0.00025 21.1 0.0 0.0006 19.8 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease COesterase PF00135.28 KIY53240.1 - 1.3e-97 327.9 0.0 3e-97 326.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY53240.1 - 1.5e-05 25.0 0.0 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KIY53240.1 - 0.0015 17.1 0.0 0.0041 15.7 0.0 1.6 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 KIY53240.1 - 0.048 13.1 0.1 0.097 12.1 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MIOX PF05153.15 KIY53241.1 - 5.1e-125 416.1 1.3 6.1e-125 415.8 1.3 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KIY53241.1 - 0.011 15.9 0.1 0.4 10.9 0.0 2.7 3 0 0 3 3 3 0 HD domain Alba PF01918.21 KIY53241.1 - 0.061 13.2 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Alba Sulfatase PF00884.23 KIY53242.1 - 5.4e-53 180.4 0.4 6.9e-53 180.0 0.4 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KIY53242.1 - 0.005 15.5 0.0 0.009 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF2330 PF10092.9 KIY53242.1 - 0.15 11.1 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) CAP PF00188.26 KIY53243.1 - 1.1e-16 61.8 3.0 1.4e-16 61.4 3.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Chorion_2 PF03964.15 KIY53243.1 - 5.5 7.9 7.4 2.3 9.1 1.8 2.3 1 1 1 2 2 2 0 Chorion family 2 SET PF00856.28 KIY53244.1 - 4.7e-12 46.6 0.0 2.4e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 SET domain F-box-like PF12937.7 KIY53246.1 - 5.9e-10 38.9 0.6 2.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like Sec23_trunk PF04811.15 KIY53247.1 - 5e-75 252.2 0.0 7.9e-75 251.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KIY53247.1 - 1.9e-29 102.2 0.0 3.8e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KIY53247.1 - 1.1e-23 83.0 0.2 2.8e-23 81.7 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KIY53247.1 - 1.3e-15 57.1 6.2 2.5e-15 56.2 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KIY53247.1 - 1.2e-13 50.7 0.0 4.2e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KIY53247.1 - 0.12 11.7 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Epimerase PF01370.21 KIY53248.1 - 1.4e-13 50.9 0.0 2.9e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY53248.1 - 2.5e-10 39.8 0.0 4.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY53248.1 - 8e-09 35.0 0.0 1.8e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KIY53248.1 - 7.5e-06 25.6 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIY53248.1 - 0.0002 20.6 0.0 0.00072 18.8 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIY53248.1 - 0.00054 19.5 0.2 0.0048 16.4 0.2 2.4 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 KIY53248.1 - 0.0009 18.9 0.0 0.035 13.6 0.1 2.3 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KIY53248.1 - 0.00094 19.1 0.0 0.003 17.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KIY53248.1 - 0.0043 17.0 0.1 0.012 15.5 0.1 1.7 1 1 0 1 1 1 1 KR domain Transket_pyr PF02779.24 KIY53250.1 - 4.1e-57 192.7 0.0 6.7e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KIY53250.1 - 3.1e-44 150.4 0.0 5e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KIY53250.1 - 2.1e-34 118.9 0.0 3.4e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Sec3_C PF09763.9 KIY53251.1 - 3.7 5.8 4.3 5.5 5.2 4.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Macoilin PF09726.9 KIY53251.1 - 7.1 5.1 6.8 12 4.3 6.8 1.3 1 0 0 1 1 1 0 Macoilin family CsbD PF05532.12 KIY53252.1 - 2.1e-13 50.0 13.6 1.2e-08 34.7 1.0 2.0 1 1 1 2 2 2 2 CsbD-like Pkinase PF00069.25 KIY53253.1 - 2.7e-71 240.1 0.0 4.1e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53253.1 - 6.6e-41 140.3 0.0 1.1e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KIY53253.1 - 3.3e-35 120.1 6.3 5.5e-18 64.9 0.3 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KIY53253.1 - 1.6e-08 34.2 0.0 1.6e-07 30.9 0.0 2.5 2 1 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KIY53253.1 - 0.0031 16.5 0.0 0.0069 15.4 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY53253.1 - 0.0034 16.8 0.1 0.027 13.8 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4524 PF15025.6 KIY53253.1 - 0.059 13.1 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) APH PF01636.23 KIY53253.1 - 0.5 10.2 2.6 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Histone_HNS PF00816.21 KIY53253.1 - 3.1 8.7 5.0 9.8 7.1 5.0 1.9 1 0 0 1 1 1 0 H-NS histone family PIP5K PF01504.18 KIY53254.1 - 7.9e-100 333.6 0.0 1.4e-99 332.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cwf_Cwc_15 PF04889.12 KIY53254.1 - 4.8 6.8 8.3 10 5.7 8.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MFS_1 PF07690.16 KIY53255.1 - 4.2e-21 75.3 24.4 5.4e-21 74.9 24.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HAD PF12710.7 KIY53260.1 - 1.8e-22 80.6 0.0 2.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KIY53260.1 - 8.6e-08 31.9 0.0 2.5e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.12 KIY53260.1 - 1.5e-05 24.7 0.1 4e-05 23.2 0.1 1.7 2 1 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KIY53260.1 - 0.00039 20.8 0.1 0.012 15.9 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cnd3 PF12719.7 KIY53262.1 - 3.8e-77 259.4 2.4 2.8e-75 253.3 0.7 2.5 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 KIY53262.1 - 1.8e-06 28.1 2.1 0.00028 21.0 0.1 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIY53262.1 - 1.1e-05 25.3 6.5 0.13 12.5 0.2 5.3 4 1 1 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KIY53262.1 - 4.9e-05 23.6 0.8 4.9e-05 23.6 0.8 3.9 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KIY53262.1 - 0.0013 19.2 5.1 0.51 10.9 0.1 5.2 4 0 0 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.7 KIY53262.1 - 0.0067 16.7 0.0 3 8.3 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 KIY53262.1 - 0.047 12.3 0.3 0.35 9.4 0.0 2.4 2 1 1 3 3 3 0 Adaptin N terminal region Corona_nucleoca PF00937.18 KIY53262.1 - 0.88 8.5 2.8 1.5 7.8 2.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HAT PF02184.16 KIY53264.1 - 3.3e-26 90.9 52.9 2.2e-08 33.9 1.4 13.7 15 1 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KIY53264.1 - 1.9e-21 74.9 35.7 0.00048 20.7 0.0 12.6 7 2 9 16 16 14 7 Tetratricopeptide repeat Suf PF05843.14 KIY53264.1 - 1.3e-14 54.9 15.8 0.0003 20.9 0.0 6.1 3 1 3 6 6 6 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KIY53264.1 - 3.2e-13 50.0 1.1 0.048 14.2 0.0 7.6 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY53264.1 - 2.5e-10 39.7 4.4 1.7 9.0 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY53264.1 - 4.1e-10 39.3 0.5 0.00043 20.5 0.0 5.6 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY53264.1 - 2.4e-07 31.3 22.1 0.31 11.7 0.0 8.0 6 4 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIY53264.1 - 3.8e-07 29.8 4.1 0.13 12.5 0.1 7.9 8 1 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY53264.1 - 8.1e-06 25.4 0.0 3.7 7.5 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY53264.1 - 4.4e-05 23.6 7.7 0.37 11.0 0.1 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIY53264.1 - 4.8e-05 22.7 22.0 1.5 8.0 0.5 5.7 2 2 4 6 6 6 4 Tetratricopeptide repeat SNAP PF14938.6 KIY53264.1 - 0.00013 21.5 6.6 0.0013 18.2 1.0 3.4 4 0 0 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 KIY53264.1 - 0.00075 20.0 13.6 32 5.4 0.0 8.9 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY53264.1 - 0.00087 19.1 5.0 5.9 7.2 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY53264.1 - 0.0021 18.1 1.7 18 5.5 0.1 4.5 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KIY53264.1 - 0.0023 17.6 0.3 9.2 6.0 0.0 4.4 5 0 0 5 5 4 1 TPR repeat U3_assoc_6 PF08640.11 KIY53264.1 - 0.04 14.0 1.0 0.04 14.0 1.0 5.3 4 3 3 7 7 7 0 U3 small nucleolar RNA-associated protein 6 Mad3_BUB1_I PF08311.12 KIY53264.1 - 0.1 12.6 29.5 0.17 11.9 2.3 7.7 5 4 2 7 7 7 0 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 KIY53264.1 - 0.13 12.5 13.0 1.9 8.8 0.1 6.8 7 3 1 8 8 7 0 Tetratricopeptide repeat DEAD PF00270.29 KIY53265.1 - 3.8e-39 134.3 0.0 1.8e-38 132.1 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY53265.1 - 4.2e-22 78.6 0.1 1.4e-20 73.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY53265.1 - 1.4e-06 28.5 0.0 3.3e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIY53265.1 - 0.021 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 KIY53265.1 - 0.12 11.5 0.0 0.26 10.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) p450 PF00067.22 KIY53266.1 - 7.5e-66 222.8 0.0 9.2e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tyrosinase PF00264.20 KIY53268.1 - 1.1e-23 84.7 6.9 5.7e-23 82.4 6.9 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase NDUFB11 PF17250.2 KIY53268.1 - 0.019 15.6 0.3 0.067 13.8 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit E1-E2_ATPase PF00122.20 KIY53270.1 - 4.5e-48 163.2 0.0 4.5e-48 163.2 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIY53270.1 - 9.6e-20 71.8 0.4 2.4e-19 70.5 0.4 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIY53270.1 - 2.2e-13 49.7 0.1 6.3e-13 48.2 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY53270.1 - 0.0003 20.6 0.0 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY53270.1 - 0.068 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Dus PF01207.17 KIY53272.1 - 3.5e-54 184.0 0.0 4.1e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KIY53272.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein IMPDH PF00478.25 KIY53272.1 - 0.024 13.7 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain adh_short_C2 PF13561.6 KIY53273.1 - 1.4e-58 198.2 0.0 1.6e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY53273.1 - 3e-53 180.2 0.1 4.6e-53 179.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY53273.1 - 8.1e-15 55.2 0.1 1.2e-14 54.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY53273.1 - 9.9e-07 28.5 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY53273.1 - 5.9e-05 22.6 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_transf_5 PF08323.11 KIY53273.1 - 0.0018 18.0 0.0 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 Starch synthase catalytic domain RmlD_sub_bind PF04321.17 KIY53273.1 - 0.086 11.9 0.3 0.31 10.1 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 KIY53273.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_N PF08240.12 KIY53274.1 - 1.1e-29 102.5 0.3 2.2e-29 101.5 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY53274.1 - 8.1e-22 77.6 1.0 1.4e-21 76.8 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY53274.1 - 4e-11 42.8 0.8 7.3e-05 22.4 0.1 2.9 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIY53274.1 - 3.1e-06 28.3 0.0 6.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIY53274.1 - 0.055 12.8 2.0 0.077 12.3 0.6 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SPC25 PF06703.11 KIY53276.1 - 2.3e-51 173.8 0.2 2.9e-51 173.5 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2757 PF10955.8 KIY53276.1 - 0.055 13.7 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Histone PF00125.24 KIY53277.1 - 8.8e-23 81.1 3.0 1.1e-22 80.8 3.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIY53277.1 - 2.8e-05 24.3 0.1 6.7e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIY53277.1 - 0.00034 21.0 0.0 0.00063 20.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KIY53277.1 - 0.017 15.1 0.4 0.02 14.9 0.4 1.1 1 0 0 1 1 1 0 YscO-like protein RP-C PF03428.13 KIY53277.1 - 0.096 12.3 0.2 0.24 11.0 0.1 1.7 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KIY53278.1 - 5.1e-18 64.5 1.5 1e-17 63.5 1.5 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KIY53278.1 - 1.6e-17 64.1 0.0 2e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIY53278.1 - 1.4e-06 28.5 0.0 2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GFO_IDH_MocA PF01408.22 KIY53279.1 - 1e-17 65.0 0.1 1.5e-17 64.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CybS PF05328.12 KIY53280.1 - 9.2e-41 138.7 0.4 8e-40 135.6 0.4 1.9 1 1 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Cullin_binding PF03556.15 KIY53281.1 - 1e-16 61.4 0.1 1.4e-16 61.1 0.1 1.1 1 0 0 1 1 1 1 Cullin binding Lipase_3 PF01764.25 KIY53282.1 - 6.6e-28 97.4 0.0 8.8e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KIY53282.1 - 0.0036 17.0 0.1 0.0051 16.6 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KIY53282.1 - 0.0038 17.9 0.0 0.0046 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KIY53282.1 - 0.01 15.5 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 KIY53282.1 - 0.019 14.5 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 KIY53282.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) p450 PF00067.22 KIY53283.1 - 1.5e-08 33.8 0.0 2.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Malic_M PF03949.15 KIY53284.1 - 1.3e-87 293.3 0.0 1.7e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIY53284.1 - 1.5e-66 223.7 0.0 2.2e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4213 PF13938.6 KIY53284.1 - 0.026 14.7 0.0 0.57 10.5 0.0 2.5 2 0 0 2 2 2 0 Putative heavy-metal chelation Abhydrolase_3 PF07859.13 KIY53286.1 - 1.6e-41 142.5 0.0 1.9e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY53286.1 - 7.3e-10 38.3 0.0 1.6e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIY53286.1 - 0.014 14.8 0.1 0.09 12.2 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KIY53286.1 - 0.13 11.9 0.1 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Putative esterase p450 PF00067.22 KIY53287.1 - 1.5e-64 218.5 0.0 1.7e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY53291.1 - 7.7e-56 189.8 0.0 1e-55 189.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.29 KIY53292.1 - 1.1e-20 74.2 0.0 5.3e-20 71.9 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY53292.1 - 0.00022 21.5 0.2 0.0055 17.0 0.0 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain Aldo_ket_red PF00248.21 KIY53293.1 - 3.8e-28 98.5 0.0 1.6e-22 80.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Amino_oxidase PF01593.24 KIY53294.1 - 1.6e-26 93.6 0.0 2e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY53294.1 - 4e-08 33.4 0.0 4e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY53294.1 - 1.7e-06 27.9 0.0 1.7e-06 27.9 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY53294.1 - 0.00026 20.3 0.1 0.0024 17.2 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY53294.1 - 0.0062 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KIY53294.1 - 0.11 13.1 0.0 0.11 13.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KIY53294.1 - 0.27 10.0 0.0 0.48 9.2 0.0 1.3 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 KIY53294.1 - 0.91 9.5 0.0 0.91 9.5 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KIY53295.1 - 3.4e-28 98.6 63.6 3.8e-14 52.4 37.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 KIY53295.1 - 0.71 10.0 2.7 1.8 8.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF962) RRM_1 PF00076.22 KIY53296.1 - 3.6e-48 161.2 0.0 3.3e-17 62.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY53296.1 - 0.00096 19.2 0.0 7 6.8 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif DUF3343 PF11823.8 KIY53296.1 - 0.0065 15.9 0.1 0.039 13.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3343) Limkain-b1 PF11608.8 KIY53296.1 - 0.12 12.5 0.0 3.3 7.9 0.0 3.0 4 1 0 4 4 4 0 Limkain b1 PRKCSH-like PF12999.7 KIY53298.1 - 0.06 13.1 0.3 0.086 12.6 0.3 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like T4_Gp59_N PF08993.10 KIY53301.1 - 0.075 13.5 0.2 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase F-box-like PF12937.7 KIY53303.1 - 2.9e-05 23.9 0.9 2.9e-05 23.9 0.9 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY53303.1 - 0.0011 18.8 2.3 0.0033 17.3 0.5 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY53304.1 - 5.6e-06 26.2 1.1 5.6e-06 26.2 1.1 2.6 2 0 0 2 2 2 1 F-box-like zf-C2H2_12 PF18658.1 KIY53304.1 - 0.43 10.2 0.0 0.43 10.2 0.0 2.4 3 0 0 3 3 3 0 Zinc-finger C2H2-type GREB1 PF15782.5 KIY53305.1 - 5.4 4.0 7.7 13 2.7 7.7 1.5 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apolipoprotein PF01442.18 KIY53306.1 - 0.00029 20.8 18.5 0.015 15.2 8.3 3.5 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain OmpH PF03938.14 KIY53306.1 - 0.023 15.1 0.7 0.023 15.1 0.7 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ApoLp-III PF07464.11 KIY53306.1 - 0.092 12.8 13.7 0.93 9.6 0.2 3.5 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KIY53306.1 - 0.33 11.0 9.9 0.45 10.5 0.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1690 PF07956.11 KIY53306.1 - 0.64 10.4 6.1 0.18 12.2 1.0 2.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) DUF1993 PF09351.10 KIY53306.1 - 0.81 9.8 7.2 0.43 10.7 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) MFS_1 PF07690.16 KIY53307.1 - 9.8e-22 77.3 55.7 3.5e-14 52.5 31.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KIY53308.1 - 0.00092 19.1 2.6 0.00096 19.0 0.3 2.2 2 0 0 2 2 2 1 F-box-like PNRC PF15365.6 KIY53309.1 - 0.021 14.6 5.1 0.021 14.6 5.1 4.4 4 0 0 4 4 4 0 Proline-rich nuclear receptor coactivator motif Vps39_2 PF10367.9 KIY53310.1 - 2.1e-08 34.6 0.0 6.7e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 vMSA PF00695.19 KIY53310.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Formyl_trans_N PF00551.19 KIY53311.1 - 1.2e-35 122.9 0.0 2.1e-35 122.1 0.0 1.3 1 1 0 1 1 1 1 Formyl transferase Ribosomal_L23eN PF03939.13 KIY53312.1 - 1.4e-23 82.8 10.9 3.2e-23 81.7 10.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KIY53312.1 - 1.6e-15 57.2 2.8 1.6e-15 57.2 2.8 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 SAP130_C PF16014.5 KIY53313.1 - 2.8 6.9 6.7 2 7.4 5.5 1.4 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus Cep57_CLD_2 PF14197.6 KIY53315.1 - 0.7 10.0 2.4 6.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Cauli_VI PF01693.16 KIY53316.1 - 4e-05 23.8 0.1 7e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Ribosomal_S17 PF00366.20 KIY53317.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 RVT_1 PF00078.27 KIY53321.1 - 7.5e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIY53322.1 - 2.1e-06 28.3 0.3 7.3e-06 26.6 0.2 2.0 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase HILPDA PF15220.6 KIY53323.1 - 0.35 11.0 1.2 6.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated Cep57_CLD PF14073.6 KIY53324.1 - 0.012 15.7 0.6 0.016 15.2 0.6 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Lebercilin PF15619.6 KIY53324.1 - 0.039 13.6 2.7 0.055 13.1 2.7 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Orthopox_F14 PF06076.12 KIY53325.1 - 0.11 12.8 0.7 0.46 10.8 0.6 2.0 2 1 0 2 2 2 0 Orthopoxvirus F14 protein Arylsulfotrans PF05935.11 KIY53326.1 - 0.084 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) KDZ PF18758.1 KIY53328.1 - 2e-55 187.9 0.0 3.1e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY53328.1 - 2.6e-39 133.7 0.3 5.2e-39 132.7 0.3 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY53328.1 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KIY53328.1 - 0.26 11.5 6.5 0.059 13.6 1.6 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.24 KIY53328.1 - 1.4 9.1 5.7 4.8 7.4 5.7 1.9 1 0 0 1 1 1 0 B-box zinc finger RVP_2 PF08284.11 KIY53329.1 - 4.9e-05 23.1 0.1 0.055 13.2 0.1 2.3 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 KIY53329.1 - 0.00029 21.0 0.1 0.0044 17.3 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 KIY53329.1 - 0.0048 17.5 0.0 0.042 14.5 0.0 2.5 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIY53329.1 - 0.0056 17.2 0.0 0.33 11.5 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease SOG2 PF10428.9 KIY53330.1 - 0.033 13.4 1.7 0.05 12.8 1.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Helitron_like_N PF14214.6 KIY53331.1 - 1.3e-24 87.5 0.1 2.8e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Spo7_2_N PF15407.6 KIY53331.1 - 0.032 13.9 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Sporulation protein family 7 ATP-synt_E PF05680.12 KIY53331.1 - 0.17 12.2 1.0 0.48 10.8 1.0 1.7 1 0 0 1 1 1 0 ATP synthase E chain Pkinase_fungal PF17667.1 KIY53332.1 - 1.8e-30 106.0 0.0 8.6e-20 70.9 0.0 3.8 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 KIY53332.1 - 7.8e-09 35.8 0.0 3.2e-05 24.0 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KIY53332.1 - 0.078 12.3 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain DEAD PF00270.29 KIY53333.1 - 5.9e-12 45.7 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY53333.1 - 1.5e-08 35.0 0.0 6.5e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY53333.1 - 2.2e-06 27.8 0.0 4.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KIY53333.1 - 0.0053 16.1 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain NAAA-beta PF15508.6 KIY53333.1 - 0.094 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase F-box-like PF12937.7 KIY53334.1 - 7.1e-08 32.2 1.7 8.7e-08 31.9 0.6 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY53334.1 - 1.7e-07 31.0 1.7 2.3e-07 30.5 0.5 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KIY53334.1 - 0.014 15.3 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 F-box MIT PF04212.18 KIY53334.1 - 0.11 12.6 0.9 0.23 11.5 0.9 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF445 PF04286.12 KIY53334.1 - 0.17 11.7 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1977 PF09320.11 KIY53335.1 - 4.4e-22 78.3 0.0 9.5e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KIY53335.1 - 4e-20 71.7 0.4 2.2e-19 69.4 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 KIY53335.1 - 0.026 14.6 0.0 0.2 11.8 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat GCP_C_terminal PF04130.13 KIY53336.1 - 6.9e-31 107.9 0.0 1.1e-30 107.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KIY53336.1 - 3.6e-17 62.9 0.0 3.9e-16 59.6 0.0 2.4 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal MFS_1 PF07690.16 KIY53337.1 - 2.7e-49 168.0 49.9 3.4e-49 167.7 49.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY53337.1 - 0.0031 16.4 37.3 0.092 11.6 17.3 3.3 1 1 1 3 3 3 2 Sugar (and other) transporter Colicin_Ia PF11504.8 KIY53337.1 - 0.073 13.2 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Colicin Ia STALD PF18185.1 KIY53337.1 - 0.2 11.0 0.4 0.91 8.8 0.1 2.1 2 0 0 2 2 2 0 Sir2- and TIR-associating SLOG family PI3_PI4_kinase PF00454.27 KIY53338.1 - 2.7e-48 165.0 0.0 5.5e-48 164.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KIY53338.1 - 3.3e-16 59.8 0.5 3.3e-16 59.8 0.5 2.5 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Ku_PK_bind PF08785.11 KIY53338.1 - 0.08 13.1 0.0 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 Ku C terminal domain like FATC PF02260.20 KIY53338.1 - 0.15 11.9 0.1 0.48 10.3 0.1 2.0 1 0 0 1 1 1 0 FATC domain MBOAT PF03062.19 KIY53339.1 - 6.8e-32 111.2 6.0 6.8e-32 111.2 6.0 2.1 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KIY53339.1 - 0.0045 17.2 3.6 0.0045 17.2 3.6 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family GPI-anchored PF10342.9 KIY53340.1 - 3.1e-11 43.9 5.5 3.1e-11 43.9 5.5 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tissue_fac PF01108.17 KIY53340.1 - 0.057 13.3 0.2 0.1 12.5 0.2 1.5 1 1 0 1 1 1 0 Tissue factor Sporozoite_P67 PF05642.11 KIY53340.1 - 0.45 8.5 10.7 0.46 8.5 10.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AF-4 PF05110.13 KIY53340.1 - 1.4 6.9 7.7 1.5 6.9 7.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 KIY53340.1 - 5 5.6 5.5 5.5 5.4 5.5 1.1 1 0 0 1 1 1 0 Macoilin family Homeobox_KN PF05920.11 KIY53341.1 - 5.6e-18 64.6 0.1 1.1e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KIY53341.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain PBD PF00786.28 KIY53343.1 - 2.6e-24 85.3 0.0 2.9e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase PF00069.25 KIY53344.1 - 4.5e-73 245.9 0.0 5.4e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53344.1 - 8.9e-49 166.1 0.0 1.2e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY53344.1 - 4.4e-06 25.7 0.0 7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY53344.1 - 0.00032 20.1 0.0 0.00054 19.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY53344.1 - 0.005 16.2 0.1 0.013 14.9 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY53344.1 - 0.006 16.5 0.2 0.17 11.8 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DSHCT PF08148.12 KIY53344.1 - 0.055 13.1 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain Asp_protease_2 PF13650.6 KIY53345.1 - 0.15 12.8 0.0 0.44 11.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 KIY53345.1 - 0.15 12.6 0.0 0.38 11.3 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease PH_10 PF15411.6 KIY53347.1 - 1.8e-24 86.3 0.0 2.9e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.6 KIY53347.1 - 5.1e-05 23.5 0.9 0.00012 22.3 0.9 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY53347.1 - 0.00016 21.7 1.1 0.00037 20.4 1.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger VWA PF00092.28 KIY53347.1 - 0.00021 21.6 0.0 0.00071 19.9 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIY53347.1 - 0.00051 20.0 0.1 0.0055 16.7 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 KIY53347.1 - 0.0016 18.3 0.1 0.0035 17.3 0.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIY53347.1 - 0.41 10.5 1.9 1.5 8.7 2.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY53347.1 - 0.71 9.7 5.7 0.27 11.0 2.7 1.9 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KIY53347.1 - 0.82 9.3 1.9 3.9 7.2 0.2 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type M20_dimer PF07687.14 KIY53350.1 - 1.4e-11 44.2 0.0 4.6e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KIY53350.1 - 5.4e-10 39.3 1.0 7.3e-10 38.9 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 F-box-like PF12937.7 KIY53351.1 - 0.00082 19.2 0.2 0.0022 17.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like DnaJ-X PF14308.6 KIY53352.1 - 8.1e-63 211.7 1.5 8.1e-63 211.7 1.5 2.1 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KIY53352.1 - 2.7e-24 85.1 2.4 7.6e-24 83.6 2.4 1.8 1 0 0 1 1 1 1 DnaJ domain Spore_III_AB PF09548.10 KIY53352.1 - 1.7 8.7 6.4 3.6 7.7 0.9 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) SIR4_SID PF16991.5 KIY53352.1 - 2.3 8.3 8.3 0.19 11.8 0.2 2.6 3 0 0 3 3 3 0 Sir4 SID domain GvpL_GvpF PF06386.11 KIY53352.1 - 7.2 6.5 15.1 0.18 11.7 3.7 2.4 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Actin PF00022.19 KIY53353.1 - 1.6e-13 50.1 0.2 7.3e-08 31.4 0.0 2.9 3 0 0 3 3 3 2 Actin Actin_micro PF17003.5 KIY53353.1 - 9.5e-08 31.6 0.0 0.00017 20.9 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family Pkinase PF00069.25 KIY53354.1 - 8.8e-21 74.4 0.1 4.6e-12 45.9 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53354.1 - 0.013 14.8 0.1 6 6.1 0.0 3.1 3 1 0 3 3 3 0 Protein tyrosine kinase zf-C3HC4 PF00097.25 KIY53356.1 - 1e-05 25.3 6.3 2e-05 24.3 6.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY53356.1 - 1.5e-05 24.9 4.4 2.2e-05 24.3 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY53356.1 - 9.3e-05 22.4 8.0 0.00045 20.2 2.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY53356.1 - 0.00012 22.4 9.9 0.00051 20.3 9.9 1.9 1 1 0 1 1 1 1 Ring finger domain Tmpp129 PF10272.9 KIY53356.1 - 0.00029 20.3 4.2 0.00034 20.0 4.2 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-C3HC4_2 PF13923.6 KIY53356.1 - 0.00096 18.9 10.0 0.089 12.7 9.9 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY53356.1 - 0.0012 19.0 5.9 0.022 14.9 6.7 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KIY53356.1 - 0.0018 18.1 6.8 0.0097 15.7 6.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY53356.1 - 0.0018 18.3 5.2 0.0039 17.2 5.2 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY53356.1 - 0.0047 17.2 9.9 0.013 15.8 9.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KIY53356.1 - 0.0071 16.2 7.8 0.11 12.4 7.8 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-WRNIP1_ubi PF18279.1 KIY53356.1 - 0.092 13.4 0.5 0.092 13.4 0.5 1.7 2 0 0 2 2 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain FANCL_C PF11793.8 KIY53356.1 - 0.13 12.4 6.1 0.35 11.1 6.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RecR PF02132.15 KIY53356.1 - 0.16 11.6 0.2 0.16 11.6 0.2 2.0 2 0 0 2 2 2 0 RecR protein DUF4038 PF13204.6 KIY53356.1 - 0.2 11.3 0.0 0.25 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) zf-RING_4 PF14570.6 KIY53356.1 - 1.4 8.7 6.7 5.6 6.8 6.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KIY53356.1 - 3 8.1 10.4 9.6 6.5 8.4 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2 PF00096.26 KIY53358.1 - 0.01 16.2 0.5 0.019 15.4 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3350 PF11830.8 KIY53358.1 - 0.019 15.3 0.5 0.032 14.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) FOXP-CC PF16159.5 KIY53358.1 - 0.026 15.2 0.2 0.034 14.8 0.2 1.2 1 0 0 1 1 1 0 FOXP coiled-coil domain STAT1_TAZ2bind PF12162.8 KIY53358.1 - 0.11 12.1 0.2 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain DUF2110 PF09883.9 KIY53358.1 - 0.19 11.3 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) zf_ZIC PF18366.1 KIY53358.1 - 0.24 11.6 1.2 0.83 9.8 1.2 1.9 1 1 0 1 1 1 0 Zic proteins zinc finger domain EBP PF05241.12 KIY53360.1 - 0.00014 21.3 3.1 0.00019 21.0 3.1 1.2 1 0 0 1 1 1 1 Emopamil binding protein DUF202 PF02656.15 KIY53361.1 - 0.00046 20.6 3.5 0.00046 20.6 3.5 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF872 PF05915.12 KIY53361.1 - 0.074 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF676 PF05057.14 KIY53362.1 - 4.9e-33 114.5 0.0 7.5e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KIY53362.1 - 4.6e-06 26.6 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KIY53362.1 - 0.2 11.4 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase SAP PF02037.27 KIY53363.1 - 0.00017 21.2 0.6 0.00017 21.2 0.6 2.0 2 0 0 2 2 2 1 SAP domain POTRA_TamA_1 PF17243.2 KIY53363.1 - 0.023 14.8 0.1 0.099 12.8 0.0 2.0 2 0 0 2 2 2 0 POTRA domain TamA domain 1 An_peroxidase PF03098.15 KIY53364.1 - 5e-39 134.3 0.1 1e-25 90.3 0.1 3.1 1 1 1 2 2 2 2 Animal haem peroxidase Coatomer_E PF04733.14 KIY53365.1 - 5.3e-44 150.8 0.0 6.1e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 KIY53365.1 - 6.1e-06 26.0 0.0 2.2 8.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY53365.1 - 9.4e-06 26.1 7.3 0.43 11.1 0.0 4.5 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIY53365.1 - 0.00016 22.0 6.1 1.5 9.7 0.6 4.5 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY53365.1 - 0.0006 20.3 1.3 4.7 8.1 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY53365.1 - 0.00064 19.4 0.0 9.5 6.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY53365.1 - 0.00085 19.6 2.0 18 5.7 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIY53365.1 - 0.01 16.0 6.4 0.041 14.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY53365.1 - 0.06 14.2 14.1 1.9 9.5 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY53365.1 - 0.091 13.0 0.0 37 4.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY53365.1 - 0.1 13.3 6.4 13 6.5 0.0 4.4 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF3552 PF12072.8 KIY53366.1 - 8.3 5.8 26.7 76 2.6 26.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) F-box-like PF12937.7 KIY53367.1 - 8e-05 22.5 2.3 0.0001 22.1 0.2 2.3 2 0 0 2 2 2 1 F-box-like RCC1 PF00415.18 KIY53369.1 - 4.8e-14 52.7 14.4 0.0011 19.5 0.0 7.2 5 2 1 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY53369.1 - 1.3e-09 37.6 26.4 9e-05 22.2 0.2 6.6 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 KIY53369.1 - 0.00061 19.6 1.2 0.0013 18.6 1.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY53369.1 - 0.00064 19.6 0.5 0.0013 18.6 0.5 1.6 1 0 0 1 1 1 1 F-box-like AMPKBI PF04739.15 KIY53369.1 - 0.0011 19.2 0.0 0.89 9.9 0.0 2.5 2 0 0 2 2 2 2 5'-AMP-activated protein kinase beta subunit, interaction domain F-box-like PF12937.7 KIY53370.1 - 1.3e-11 44.2 0.1 2.6e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY53370.1 - 0.0032 17.8 0.4 0.32 11.5 0.0 3.8 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY53370.1 - 0.14 12.0 1.4 0.86 9.6 0.0 2.9 3 0 0 3 3 3 0 F-box domain Hydrolase_4 PF12146.8 KIY53371.1 - 1.4e-14 54.0 0.0 1.2e-12 47.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY53371.1 - 3.3e-08 33.5 0.1 3e-06 27.1 0.2 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY53371.1 - 2.4e-06 28.3 0.0 2.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KIY53371.1 - 5.6e-05 23.0 0.0 0.19 11.5 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KIY53371.1 - 5.7e-05 22.8 0.0 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KIY53371.1 - 0.0081 15.6 0.0 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KIY53371.1 - 0.019 13.7 0.0 0.053 12.2 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KIY53371.1 - 0.03 14.3 0.2 0.26 11.2 0.0 2.4 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KIY53371.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KIY53371.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KIY53371.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF818 PF05677.12 KIY53371.1 - 0.14 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PH_12 PF16457.5 KIY53372.1 - 7.7e-33 113.9 0.0 1.3e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KIY53372.1 - 2.2e-26 92.6 0.0 5.7e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KIY53372.1 - 1.4e-25 90.4 0.0 2.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family MTHFR PF02219.17 KIY53373.1 - 1.2e-102 343.1 0.0 1.6e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase FGGY_N PF00370.21 KIY53374.1 - 4.9e-22 78.7 0.0 1.6e-13 50.8 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIY53374.1 - 1.6e-18 67.1 0.3 3.9e-18 65.9 0.0 1.8 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain RRP36 PF06102.12 KIY53375.1 - 2.2e-42 144.8 16.5 3.7e-42 144.1 16.5 1.3 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 HisKA PF00512.25 KIY53375.1 - 0.24 11.4 3.7 28 4.8 3.7 2.6 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain MCR_C PF04609.12 KIY53375.1 - 1.3 8.0 4.6 0.51 9.4 1.9 1.6 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C SUZ PF12752.7 KIY53377.1 - 1.1e-14 54.9 6.1 5.2e-14 52.7 6.1 1.9 1 1 0 1 1 1 1 SUZ domain R3H PF01424.22 KIY53377.1 - 0.00098 19.1 0.1 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 R3H domain DUF3599 PF12206.8 KIY53377.1 - 0.084 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) TauD PF02668.16 KIY53378.1 - 3.4e-47 161.5 0.1 4e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CorA PF01544.18 KIY53379.1 - 1.8e-16 60.3 0.8 1.7e-14 53.9 0.8 2.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein LtrA PF06772.11 KIY53379.1 - 0.025 13.8 0.2 0.036 13.3 0.2 1.2 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) zf-C2H2 PF00096.26 KIY53380.1 - 1.1e-33 113.8 69.7 0.001 19.4 4.8 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY53380.1 - 3.8e-19 67.7 65.2 0.0041 17.8 2.3 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY53380.1 - 8.8e-10 38.6 4.2 3.2e-06 27.3 0.9 11.6 10 2 1 11 11 11 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIY53380.1 - 6.7e-07 29.4 38.4 0.12 12.7 0.9 9.2 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KIY53380.1 - 1.6e-06 28.3 23.2 0.1 12.9 6.1 5.5 1 1 4 5 5 5 3 C2H2-type zinc ribbon zf-met PF12874.7 KIY53380.1 - 0.00049 20.4 29.3 0.41 11.1 1.8 8.4 8 0 0 8 8 8 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIY53380.1 - 0.22 11.6 42.7 1.8 8.7 1.3 8.4 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIY53380.1 - 1.3 9.1 0.0 1.3 9.1 0.0 6.4 3 2 3 7 7 7 0 Aberrant zinc-finger zf_ZIC PF18366.1 KIY53380.1 - 9.2 6.5 22.4 2.3 8.4 0.1 5.9 6 1 1 7 7 7 0 Zic proteins zinc finger domain HLH PF00010.26 KIY53381.1 - 2.4e-12 46.6 0.8 4.8e-12 45.6 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aa_trans PF01490.18 KIY53383.1 - 1.3e-80 271.1 24.7 1.6e-80 270.8 24.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KIY53383.1 - 0.003 16.7 19.8 0.003 16.7 19.8 2.5 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family PIF1 PF05970.14 KIY53384.1 - 8.6e-53 179.8 0.3 5.5e-42 144.2 0.1 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KIY53384.1 - 7e-21 74.8 0.0 1.2e-19 70.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY53384.1 - 3.8e-11 43.5 0.0 7.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KIY53384.1 - 4.1e-07 28.4 0.4 5.9e-06 24.5 0.0 2.2 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 KIY53384.1 - 4.5e-05 23.7 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY53384.1 - 0.00033 21.1 0.1 0.00079 19.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIY53384.1 - 0.0004 20.4 0.3 0.0051 16.8 0.3 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea UvrD_C_2 PF13538.6 KIY53384.1 - 0.00078 19.2 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 KIY53384.1 - 0.001 18.6 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 KIY53384.1 - 0.0021 17.6 0.0 0.024 14.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.18 KIY53384.1 - 0.0081 15.9 0.6 2.6 7.7 0.2 2.8 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KIY53384.1 - 0.022 14.0 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KIY53384.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 KIY53384.1 - 0.029 14.2 0.2 0.75 9.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KIY53384.1 - 0.039 13.2 0.1 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KIY53384.1 - 0.042 13.6 0.1 0.28 10.9 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KIY53384.1 - 0.045 14.2 0.1 0.13 12.7 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KIY53384.1 - 0.063 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_32 PF13654.6 KIY53384.1 - 0.096 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KIY53384.1 - 0.13 12.2 1.0 0.54 10.1 0.5 2.3 2 1 0 2 2 2 0 Helicase TrwB_AAD_bind PF10412.9 KIY53384.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF5605 PF18310.1 KIY53384.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) DEAD PF00270.29 KIY53384.1 - 0.17 11.6 0.1 2.4 7.9 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KIY53384.1 - 0.18 12.2 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase STT3 PF02516.14 KIY53385.1 - 2.1e-143 478.8 38.0 1.9e-137 459.2 33.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit UCH PF00443.29 KIY53386.1 - 5.6e-67 225.9 0.0 1e-66 225.1 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY53386.1 - 7.4e-14 52.1 0.0 6.6e-06 25.9 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KIY53386.1 - 2.7e-13 50.4 0.0 7.3e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Arc_C PF18162.1 KIY53386.1 - 0.16 11.8 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Arc C-lobe PseudoU_synth_1 PF01416.20 KIY53389.1 - 6.2e-11 42.7 0.0 8.7e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase NpwBP PF12622.7 KIY53389.1 - 0.096 13.5 0.7 0.28 12.0 0.7 1.8 1 0 0 1 1 1 0 mRNA biogenesis factor DUF1996 PF09362.10 KIY53391.1 - 1.9e-75 253.9 0.2 2.4e-75 253.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RNA_pol_Rpb4 PF03874.16 KIY53392.1 - 2.3e-18 66.7 0.1 2.6e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 CDC27 PF09507.10 KIY53393.1 - 8e-33 114.5 87.1 6.7e-32 111.4 67.8 3.7 1 1 1 2 2 2 1 DNA polymerase subunit Cdc27 Cupin_2 PF07883.11 KIY53394.1 - 0.0004 20.0 0.0 0.00068 19.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Thump_like PF18096.1 KIY53394.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 1 0 1 1 1 0 THUMP domain-like UAA PF08449.11 KIY53395.1 - 9.8e-44 149.8 12.8 3.6e-43 147.9 12.8 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIY53395.1 - 6.5e-06 26.4 12.7 6.5e-06 26.4 12.7 4.2 3 2 1 4 4 4 1 EamA-like transporter family CRT-like PF08627.10 KIY53395.1 - 0.0015 17.5 5.7 0.044 12.7 0.9 2.3 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KIY53395.1 - 0.0036 16.5 1.2 1.2 8.2 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 KIY53395.1 - 0.015 14.6 5.6 0.26 10.6 0.6 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF370 PF04025.12 KIY53395.1 - 0.15 12.2 0.2 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF370) DUF3450 PF11932.8 KIY53396.1 - 0.011 15.0 1.0 0.021 14.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.8 KIY53396.1 - 5.7 7.0 7.8 1 9.4 0.7 2.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding KxDL PF10241.9 KIY53396.1 - 5.8 7.3 6.0 0.41 11.0 0.4 1.9 3 0 0 3 3 3 0 Uncharacterized conserved protein GPI-anchored PF10342.9 KIY53397.1 - 2.7e-09 37.6 0.2 2.7e-09 37.6 0.2 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CBM26 PF16738.5 KIY53397.1 - 0.093 13.0 0.4 0.77 10.1 0.0 2.2 2 0 0 2 2 2 0 Starch-binding module 26 RIFIN PF02009.16 KIY53397.1 - 1.7 8.5 3.9 2.3 8.0 3.9 1.1 1 0 0 1 1 1 0 Rifin Aminotran_5 PF00266.19 KIY53399.1 - 3.2e-14 52.7 0.0 1.1e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIY53399.1 - 2.9e-05 23.4 0.0 5.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIY53399.1 - 0.029 13.7 0.0 0.14 11.4 0.0 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 KIY53399.1 - 0.045 12.4 0.0 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS PMI_typeI PF01238.21 KIY53400.1 - 1.1e-109 367.1 0.0 1.2e-109 366.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 KIY53400.1 - 0.0045 16.9 0.1 0.14 12.1 0.0 2.7 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_2 PF07883.11 KIY53400.1 - 0.0081 15.9 0.0 5 6.9 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_N PF06719.13 KIY53400.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus WD40 PF00400.32 KIY53401.1 - 6e-11 42.7 1.3 0.015 16.1 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY53401.1 - 3.9e-06 27.1 0.1 1.2 9.5 0.0 4.5 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KIY53401.1 - 0.055 12.5 0.0 0.21 10.6 0.0 1.8 1 1 1 2 2 2 0 Coatomer WD associated region Aldo_ket_red PF00248.21 KIY53403.1 - 1.6e-70 237.6 0.1 2.1e-70 237.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIY53404.1 - 1.3e-16 60.6 0.0 1.4e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIY53406.1 - 2e-72 243.9 0.2 2.5e-72 243.5 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_FMN PF00724.20 KIY53407.1 - 6.4e-89 298.6 0.0 7.3e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NAD_binding_10 PF13460.6 KIY53408.1 - 0.00059 19.8 0.0 0.00065 19.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KIY53409.1 - 7.3e-16 58.3 0.0 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY53409.1 - 8.6e-15 54.6 0.5 2.7e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY53409.1 - 1.7e-06 29.1 0.0 4.2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIY53409.1 - 0.15 12.3 0.1 0.45 10.8 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Aldo_ket_red PF00248.21 KIY53410.1 - 7.2e-74 248.6 0.3 8.7e-74 248.4 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HlyIII PF03006.20 KIY53411.1 - 2.6e-40 138.5 20.1 3.4e-40 138.2 20.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Sugar_tr PF00083.24 KIY53412.1 - 4.4e-101 339.0 15.3 8.3e-101 338.1 15.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY53412.1 - 9.2e-21 74.1 14.0 9.2e-21 74.1 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TraI PF07057.11 KIY53412.1 - 0.19 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA helicase TraI DUF4139 PF13598.6 KIY53413.1 - 1.4e-48 165.4 0.4 2.3e-48 164.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KIY53413.1 - 4.1e-14 52.8 2.4 7.7e-14 51.9 0.5 2.4 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) BBS2_C PF14782.6 KIY53413.1 - 0.047 12.4 1.9 0.097 11.4 1.9 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal APG6_N PF17675.1 KIY53413.1 - 2.5 8.6 5.8 8.2 7.0 2.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region PC-Esterase PF13839.6 KIY53414.1 - 1.2e-07 31.8 0.0 2.3e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p FAD_binding_3 PF01494.19 KIY53416.1 - 8.3e-14 51.6 0.0 2.5e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIY53416.1 - 6.2e-11 42.5 0.1 0.00026 20.7 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY53416.1 - 3.2e-09 36.4 0.3 1.4e-06 27.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIY53416.1 - 1.8e-08 34.0 0.0 0.00029 20.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY53416.1 - 3.2e-07 30.5 0.4 9.1e-07 29.0 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIY53416.1 - 1e-05 24.5 0.1 7.8e-05 21.5 0.1 2.0 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KIY53416.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KIY53416.1 - 0.0006 19.0 0.0 0.00092 18.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KIY53416.1 - 0.0025 18.4 0.2 0.017 15.6 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY53416.1 - 0.0068 15.5 0.3 0.53 9.3 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KIY53416.1 - 0.007 15.7 0.2 0.21 10.8 0.1 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KIY53416.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY53416.1 - 0.016 14.6 0.3 0.028 13.8 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KIY53416.1 - 0.024 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KIY53416.1 - 0.052 12.4 0.0 0.53 9.1 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase TRI5 PF06330.11 KIY53417.1 - 9.2e-22 77.4 0.1 1.1e-21 77.1 0.1 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) PRP38 PF03371.15 KIY53417.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 PRP38 family Stathmin PF00836.19 KIY53418.1 - 0.16 11.9 0.2 0.26 11.3 0.2 1.3 1 0 0 1 1 1 0 Stathmin family Glyco_tranf_2_3 PF13641.6 KIY53419.1 - 2.1e-29 103.1 0.0 3.1e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIY53419.1 - 1.3e-08 34.8 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIY53419.1 - 1.5e-07 31.0 0.1 9.1e-07 28.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KIY53419.1 - 0.12 12.3 7.1 0.29 11.0 7.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Creatinase_N_2 PF16189.5 KIY53421.1 - 2e-42 145.0 0.0 2.5e-41 141.5 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KIY53421.1 - 2.1e-41 141.9 0.0 3e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KIY53421.1 - 1e-19 70.4 0.5 3.4e-19 68.7 0.5 2.0 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KIY53421.1 - 6.7e-19 68.9 0.0 1.6e-18 67.6 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain MFS_1 PF07690.16 KIY53422.1 - 1.1e-36 126.5 45.2 1.3e-35 123.0 44.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY53422.1 - 5.8e-12 45.2 8.3 5.8e-12 45.2 8.3 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KIY53422.1 - 1.7e-10 40.0 2.9 1.7e-10 40.0 2.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIY53422.1 - 8.3e-07 28.6 4.3 8.3e-07 28.6 4.3 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB G-alpha PF00503.20 KIY53423.1 - 1.4e-81 274.4 0.0 1.7e-81 274.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY53423.1 - 1.5e-05 24.6 0.0 0.0057 16.1 0.0 3.3 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY53423.1 - 0.052 13.1 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 KIY53423.1 - 0.11 12.7 0.0 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIY53423.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Amidohydro_1 PF01979.20 KIY53424.1 - 1.6e-14 54.0 0.1 1.7e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIY53424.1 - 1.9e-13 50.7 0.7 4.4e-08 33.0 0.1 2.5 2 0 0 2 2 2 2 Amidohydrolase family LRR_8 PF13855.6 KIY53425.1 - 3.9e-49 164.2 51.0 1.6e-11 43.8 1.9 10.7 8 2 3 11 11 11 8 Leucine rich repeat PP2C PF00481.21 KIY53425.1 - 3.1e-42 145.0 0.0 5.1e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 KIY53425.1 - 1.6e-39 133.2 57.3 4.7e-05 23.7 0.1 12.3 7 2 2 11 11 11 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KIY53425.1 - 3.2e-24 85.6 0.0 5.8e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KIY53425.1 - 6.8e-07 29.0 25.0 0.069 12.7 0.1 6.7 2 2 5 8 8 8 4 Leucine-rich repeat LRR_1 PF00560.33 KIY53425.1 - 0.0012 19.1 44.6 0.22 12.2 0.3 15.3 16 2 1 17 17 17 1 Leucine Rich Repeat LRR_6 PF13516.6 KIY53425.1 - 0.12 12.5 51.4 0.39 10.9 0.3 13.3 15 0 0 15 15 15 0 Leucine Rich repeat Aldo_ket_red PF00248.21 KIY53427.1 - 6.9e-68 229.0 0.0 9.4e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SET PF00856.28 KIY53428.1 - 2.3e-12 47.6 0.1 1e-11 45.5 0.1 2.0 1 1 0 1 1 1 1 SET domain Aldo_ket_red PF00248.21 KIY53429.1 - 9.2e-66 222.0 0.0 1.1e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bac_rhamnosid6H PF17389.2 KIY53430.1 - 4.9e-14 52.3 0.4 4.9e-14 52.3 0.4 1.5 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KIY53430.1 - 1.8e-07 30.8 0.0 5.5e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 KIY53430.1 - 0.0015 17.5 0.1 0.0045 16.0 0.1 1.7 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 KIY53430.1 - 0.02 13.7 0.1 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 Trehalase Bac_rhamnosid PF05592.11 KIY53430.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Aldo_ket_red PF00248.21 KIY53431.1 - 2.2e-52 178.1 0.0 3.1e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 KIY53432.1 - 9.9e-51 172.9 0.0 8.7e-41 140.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Pept_tRNA_hydro PF01195.19 KIY53433.1 - 5.6e-29 101.3 0.0 6.5e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Epimerase PF01370.21 KIY53434.1 - 1.5e-15 57.3 0.2 5.4e-15 55.5 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY53434.1 - 4.7e-13 48.8 0.0 6.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY53434.1 - 2.7e-10 39.9 0.0 4.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KIY53434.1 - 1.8e-09 37.7 0.1 8.6e-08 32.3 0.1 2.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIY53434.1 - 1.1e-07 31.6 0.1 2.4e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIY53434.1 - 6.8e-07 29.1 0.1 1.1e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KIY53434.1 - 1.8e-05 24.0 0.0 0.00021 20.6 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KIY53434.1 - 0.00013 22.0 0.1 0.00061 19.8 0.0 2.0 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 KIY53434.1 - 0.00058 19.4 1.4 0.0025 17.3 0.4 2.3 2 1 0 2 2 2 1 short chain dehydrogenase cwf21 PF08312.12 KIY53435.1 - 4.9e-15 55.4 5.7 4.9e-15 55.4 5.7 2.7 2 1 0 2 2 2 1 cwf21 domain DUF4031 PF13223.6 KIY53435.1 - 0.058 13.6 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) GMC_oxred_N PF00732.19 KIY53436.1 - 5.8e-20 71.8 0.0 6.6e-19 68.4 0.0 2.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY53436.1 - 1.5e-16 61.2 0.1 7.6e-16 58.9 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIY53436.1 - 2.8e-07 30.0 0.0 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIY53436.1 - 2.5e-05 23.5 0.2 0.00032 19.8 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY53436.1 - 8.4e-05 21.9 0.2 0.002 17.4 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY53436.1 - 0.00011 21.1 0.2 0.00019 20.3 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KIY53436.1 - 0.00015 21.1 0.0 0.00036 19.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY53436.1 - 0.00044 19.6 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY53436.1 - 0.00074 19.7 0.3 0.0027 17.9 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIY53436.1 - 0.0039 16.6 0.3 0.058 12.7 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIY53436.1 - 0.013 16.0 1.3 0.17 12.5 0.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY53436.1 - 0.033 13.4 0.2 0.062 12.5 0.2 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 KIY53436.1 - 0.093 12.4 0.4 0.21 11.3 0.4 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KIY53436.1 - 0.095 12.3 2.0 0.18 11.4 0.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pkinase PF00069.25 KIY53437.1 - 1.6e-07 30.9 0.0 3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIY53437.1 - 0.00029 20.2 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY53437.1 - 0.00041 20.3 1.8 0.0016 18.4 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Exo_endo_phos PF03372.23 KIY53437.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Pkinase_Tyr PF07714.17 KIY53437.1 - 0.15 11.4 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3131 PF11329.8 KIY53438.1 - 0.0098 15.0 0.1 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3131) Glyco_hydro_92 PF07971.12 KIY53439.1 - 3.3e-119 398.8 0.6 4e-119 398.6 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIY53439.1 - 3.7e-46 157.9 0.0 6.5e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain HMG_box PF00505.19 KIY53441.1 - 0.00072 19.9 0.4 0.00072 19.9 0.4 2.8 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY53441.1 - 0.0026 18.3 0.2 0.0065 17.0 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain Bac_rhamnosid_C PF17390.2 KIY53443.1 - 4.5e-07 29.6 0.0 1.7e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KIY53443.1 - 0.0071 15.6 1.2 0.0073 15.6 0.0 1.5 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 KIY53443.1 - 0.0081 15.0 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.11 KIY53443.1 - 0.041 13.8 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Aldo_ket_red PF00248.21 KIY53445.1 - 1.1e-63 215.2 0.0 1.3e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RING_5 PF14634.6 KIY53446.1 - 5.6e-06 26.2 8.2 9.3e-06 25.5 8.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY53446.1 - 4.1e-05 23.8 8.6 7e-05 23.1 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain ERM PF00769.19 KIY53446.1 - 0.00011 22.2 19.3 0.00011 22.2 19.3 2.9 1 1 2 3 3 3 1 Ezrin/radixin/moesin family zf-C3HC4_2 PF13923.6 KIY53446.1 - 0.00026 20.8 9.0 0.00046 20.0 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY53446.1 - 0.0013 18.7 7.7 0.0023 17.9 7.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KIY53446.1 - 0.0029 17.3 6.8 0.0068 16.1 6.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger TMF_DNA_bd PF12329.8 KIY53446.1 - 0.0039 17.2 7.9 0.0039 17.2 7.9 3.4 2 2 2 4 4 4 1 TATA element modulatory factor 1 DNA binding Prok-RING_4 PF14447.6 KIY53446.1 - 0.0067 16.3 8.2 0.013 15.3 8.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HrpB7 PF09486.10 KIY53446.1 - 0.0079 16.6 5.5 0.0079 16.6 5.5 3.9 1 1 2 3 3 3 1 Bacterial type III secretion protein (HrpB7) Lzipper-MIP1 PF14389.6 KIY53446.1 - 0.0096 16.2 6.3 0.64 10.3 6.3 2.8 1 1 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 zf-C3HC4 PF00097.25 KIY53446.1 - 0.017 15.0 8.8 0.03 14.2 8.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Filament PF00038.21 KIY53446.1 - 0.02 14.5 25.7 0.44 10.1 13.7 2.3 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 KIY53446.1 - 0.031 14.3 11.0 0.29 11.2 6.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KIY53446.1 - 0.037 14.5 28.2 0.15 12.5 19.2 2.6 1 1 2 3 3 3 0 Fez1 ATG16 PF08614.11 KIY53446.1 - 0.059 13.6 35.0 0.21 11.8 9.3 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 KIY53446.1 - 0.068 13.6 7.1 0.039 14.4 3.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 KIY53446.1 - 0.089 13.4 24.8 0.065 13.9 3.2 4.8 3 2 2 5 5 4 0 SlyX bZIP_1 PF00170.21 KIY53446.1 - 0.091 12.9 8.9 0.59 10.3 5.2 3.0 2 1 0 2 2 2 0 bZIP transcription factor DUF16 PF01519.16 KIY53446.1 - 0.091 13.3 16.8 0.95 10.0 3.8 3.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Laminin_II PF06009.12 KIY53446.1 - 0.11 12.5 11.8 0.24 11.4 5.0 2.8 1 1 1 2 2 2 0 Laminin Domain II MbeD_MobD PF04899.12 KIY53446.1 - 0.28 11.3 12.4 2 8.6 0.3 4.2 3 1 1 4 4 4 0 MbeD/MobD like Stc1 PF12898.7 KIY53446.1 - 0.36 11.4 2.5 52 4.5 0.0 3.4 2 0 0 2 2 2 0 Stc1 domain DUF4201 PF13870.6 KIY53446.1 - 0.69 9.6 25.9 2 8.1 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.9 KIY53446.1 - 0.7 10.1 25.7 0.4 10.9 11.0 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 KASH_CCD PF14662.6 KIY53446.1 - 0.76 9.6 25.1 0.069 13.0 18.2 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 KIY53446.1 - 1.2 9.3 10.8 0.79 9.9 7.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KIY53446.1 - 2.1 7.1 27.9 4.9 5.9 19.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 KIY53446.1 - 2.5 7.6 24.0 0.039 13.5 12.3 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 zf-RING_4 PF14570.6 KIY53446.1 - 5.6 6.8 7.0 12 5.8 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain BST2 PF16716.5 KIY53446.1 - 6.1 7.5 17.7 10 6.7 0.1 3.7 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 T3SSipB PF16535.5 KIY53446.1 - 6.9 7.1 13.9 3.8 8.0 3.6 2.8 1 1 1 2 2 2 0 Type III cell invasion protein SipB TPR_MLP1_2 PF07926.12 KIY53446.1 - 7.5 6.6 30.9 0.31 11.1 6.2 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 KIY53446.1 - 9.5 4.0 16.8 6.7 4.5 15.1 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 KIY53446.1 - 9.6 5.5 23.0 33 3.7 8.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ATG7_N PF16420.5 KIY53447.1 - 2e-74 251.0 0.6 1.2e-72 245.1 0.6 2.4 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KIY53447.1 - 7.8e-47 159.7 0.0 1.5e-46 158.7 0.0 1.4 2 0 0 2 2 2 1 ThiF family 2-Hacid_dh_C PF02826.19 KIY53447.1 - 0.0068 15.8 0.0 0.7 9.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY53447.1 - 0.04 14.0 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KIY53447.1 - 0.05 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.21 KIY53447.1 - 0.053 13.2 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MDM31_MDM32 PF08118.11 KIY53448.1 - 4e-201 669.3 0.1 4.9e-201 669.0 0.1 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins APAF1_C PF17908.1 KIY53448.1 - 0.2 11.7 0.9 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 APAF-1 helical domain AFG1_ATPase PF03969.16 KIY53451.1 - 5.2e-09 35.5 0.0 0.00055 18.9 0.0 3.1 1 1 2 3 3 3 3 AFG1-like ATPase ATG22 PF11700.8 KIY53453.1 - 1.1e-21 77.0 0.7 1.1e-21 77.0 0.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF2070 PF09843.9 KIY53453.1 - 7.4 4.7 7.0 8.9 4.5 7.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SBF PF01758.16 KIY53456.1 - 6.1e-40 137.0 11.4 6.1e-40 137.0 11.4 2.3 3 0 0 3 3 3 1 Sodium Bile acid symporter family Mid2 PF04478.12 KIY53456.1 - 0.16 11.8 0.3 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Bac_export_3 PF01313.19 KIY53456.1 - 6.7 6.7 12.0 0.7 9.9 0.4 3.5 3 0 0 3 3 3 0 Bacterial export proteins, family 3 ADIP PF11559.8 KIY53457.1 - 0.0037 17.4 31.2 0.034 14.2 21.0 2.8 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KIY53457.1 - 0.027 13.5 27.5 0.9 8.6 19.6 2.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KIY53457.1 - 0.028 14.9 23.1 0.13 12.7 14.9 2.3 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 KIY53457.1 - 0.15 10.9 23.4 0.23 10.3 10.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KIY53457.1 - 0.16 12.0 22.1 2.7 8.1 0.2 3.4 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3866 PF12982.7 KIY53457.1 - 0.25 10.4 1.0 0.38 9.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) DUF641 PF04859.12 KIY53457.1 - 0.54 10.6 19.9 0.86 9.9 8.7 3.6 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 KIY53457.1 - 0.63 10.1 12.6 13 5.8 3.3 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 KIY53457.1 - 0.87 9.4 11.3 0.74 9.6 6.4 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 HrpB7 PF09486.10 KIY53457.1 - 1.1 9.6 28.3 0.56 10.6 10.7 2.8 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.9 KIY53457.1 - 1.2 9.2 28.4 1.2 9.1 10.8 3.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 KIY53457.1 - 1.5 7.4 17.5 0.67 8.5 8.5 2.4 1 1 1 2 2 2 0 AAA domain UPF0242 PF06785.11 KIY53457.1 - 1.6 8.8 26.5 0.38 10.8 18.0 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SseC PF04888.12 KIY53457.1 - 1.9 8.0 10.1 1 8.9 0.2 2.4 2 1 0 2 2 2 0 Secretion system effector C (SseC) like family HIP1_clath_bdg PF16515.5 KIY53457.1 - 2.6 8.7 25.4 2.1 9.0 8.8 3.4 1 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-Q PF13094.6 KIY53457.1 - 4.3 7.5 27.5 4.8 7.4 7.4 3.3 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF5082 PF16888.5 KIY53457.1 - 5.3 7.3 18.1 0.44 10.8 7.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 KIY53457.1 - 5.9 6.1 25.0 0.35 10.1 5.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) SlyX PF04102.12 KIY53457.1 - 6 7.6 29.2 0.7 10.6 0.9 4.3 2 1 0 3 3 3 0 SlyX VHS PF00790.19 KIY53458.1 - 3.9e-11 43.0 0.0 7.3e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KIY53458.1 - 0.00024 21.4 2.2 0.00026 21.2 0.5 2.0 2 0 0 2 2 2 1 GAT domain HSM3_N PF18795.1 KIY53458.1 - 0.045 13.2 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain TFIIA PF03153.13 KIY53460.1 - 2.8e-05 24.3 15.6 5.3e-05 23.4 15.6 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 KIY53460.1 - 0.00013 20.4 31.1 0.00023 19.6 31.1 1.5 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 KIY53460.1 - 0.0012 18.3 31.6 0.0017 17.9 31.6 1.2 1 0 0 1 1 1 1 SDA1 Drc1-Sld2 PF11719.8 KIY53460.1 - 0.028 14.0 8.9 0.036 13.6 8.9 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein SAPS PF04499.15 KIY53460.1 - 0.38 9.5 9.6 0.57 8.9 9.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 KIY53460.1 - 0.72 9.6 13.2 1.2 8.9 13.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KIY53460.1 - 1.5 7.7 7.7 5.5 5.9 6.8 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Bax1-I PF01027.20 KIY53461.1 - 1.3e-41 142.8 29.8 2.5e-41 141.8 29.8 1.4 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KIY53461.1 - 2.4 7.6 19.3 8.1 5.9 19.3 1.9 1 1 0 1 1 1 0 Bax inhibitor 1 like ArgoN PF16486.5 KIY53462.1 - 3e-13 50.6 0.0 3.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of argonaute FoP_duplication PF13865.6 KIY53462.1 - 0.75 10.4 12.4 1.3 9.7 12.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Creatinase_N_2 PF16189.5 KIY53464.1 - 4.2e-52 176.5 0.0 5.1e-51 173.0 0.0 2.4 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KIY53464.1 - 6.1e-46 156.8 0.0 8.3e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KIY53464.1 - 1e-25 89.6 0.0 2.9e-25 88.1 0.0 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KIY53464.1 - 1.6e-25 90.2 0.1 9.4e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain CSTF_C PF14304.6 KIY53465.1 - 1.9e-07 30.6 1.8 1.7e-06 27.5 0.5 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 KIY53465.1 - 8.6e-07 29.3 0.8 8.6e-07 29.3 0.8 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 PsaN PF05479.11 KIY53465.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Aldo_ket_red PF00248.21 KIY53466.1 - 8.7e-68 228.7 0.0 1e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DsrD PF08679.11 KIY53466.1 - 0.12 12.6 0.0 0.58 10.4 0.0 2.0 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Vps62 PF06101.11 KIY53467.1 - 5.9e-09 34.8 2.5 6.2e-09 34.7 0.8 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 ATP-synt PF00231.19 KIY53468.1 - 1.9e-72 244.3 0.7 2.2e-72 244.1 0.7 1.0 1 0 0 1 1 1 1 ATP synthase Exo_endo_phos PF03372.23 KIY53469.1 - 2.6e-18 66.4 0.9 2.2e-17 63.4 0.9 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KIY53469.1 - 4e-15 55.7 3.2 3.9e-07 30.3 0.0 3.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY53469.1 - 2.3e-12 46.5 11.3 4e-09 36.1 4.9 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KIY53469.1 - 0.00059 20.0 2.0 13 6.8 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KIY53469.1 - 2.9 8.2 10.3 7.6 6.9 0.2 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Glyco_hydro_3_C PF01915.22 KIY53470.1 - 1.7e-42 145.7 0.0 2.8e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY53470.1 - 2.2e-38 132.4 0.0 3.3e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY53470.1 - 4.7e-20 71.5 0.1 1.4e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Rpr2 PF04032.16 KIY53471.1 - 6.5e-18 64.8 6.0 6.5e-18 64.8 6.0 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain T4_baseplate PF12322.8 KIY53471.1 - 0.0026 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 T4 bacteriophage base plate protein CEBP1_N PF16368.5 KIY53471.1 - 0.006 16.1 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein 1 N-terminus AvrE_T3Es PF11725.8 KIY53471.1 - 0.059 10.6 0.1 0.074 10.3 0.1 1.1 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) ADH_N PF08240.12 KIY53472.1 - 1.2e-22 79.8 1.9 1.9e-22 79.2 1.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY53472.1 - 1.4e-14 54.2 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY53472.1 - 2.3e-05 23.9 0.1 3.8e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY53472.1 - 8.1e-05 22.0 0.4 0.00016 21.0 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KIY53472.1 - 0.0094 16.1 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KIY53472.1 - 0.015 15.2 0.2 0.022 14.7 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KIY53472.1 - 0.058 14.2 0.0 0.88 10.4 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.21 KIY53472.1 - 0.17 11.2 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 ThiF family HMG_box PF00505.19 KIY53473.1 - 0.012 16.1 0.1 0.036 14.5 0.1 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box CxC2 PF18803.1 KIY53474.1 - 1e-29 102.8 1.0 2.1e-29 101.8 1.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY53474.1 - 7.2e-05 22.9 0.3 7.2e-05 22.9 0.3 1.6 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY53474.1 - 0.0032 17.3 0.9 0.005 16.7 0.3 1.7 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY53475.1 - 1.2e-11 44.7 1.5 1.3e-11 44.5 1.5 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF4202 PF13875.6 KIY53476.1 - 0.092 12.6 1.5 0.54 10.1 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4202) DUF659 PF04937.15 KIY53479.1 - 3.7e-06 26.9 0.1 8.4e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Ribosomal_L37e PF01907.19 KIY53480.1 - 7.5e-27 93.2 13.8 1.5e-26 92.3 13.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KIY53480.1 - 0.0065 16.5 1.8 0.0098 15.9 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 KIY53480.1 - 0.0093 16.0 3.4 0.015 15.4 3.4 1.5 1 1 0 1 1 1 1 SelR domain LIM PF00412.22 KIY53480.1 - 0.015 15.5 2.4 0.023 14.9 2.4 1.3 1 0 0 1 1 1 0 LIM domain HypA PF01155.19 KIY53480.1 - 0.041 13.9 0.8 0.06 13.4 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KIY53480.1 - 0.41 10.4 3.8 6.4 6.6 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KIY53480.1 - 0.62 10.0 5.3 6.1 6.8 6.3 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zn-ribbon_14 PF16503.5 KIY53480.1 - 1.1 8.9 5.8 0.81 9.2 0.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon DUF647 PF04884.14 KIY53481.1 - 8.9e-58 195.8 5.8 2.9e-54 184.2 1.7 2.1 1 1 1 2 2 2 2 Vitamin B6 photo-protection and homoeostasis DUF4516 PF14990.6 KIY53481.1 - 0.1 12.3 0.6 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) IF4E PF01652.18 KIY53482.1 - 3.8e-54 182.8 0.0 5.2e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.11 KIY53482.1 - 0.081 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) Trp_halogenase PF04820.14 KIY53484.1 - 2.5e-32 112.3 0.0 1.1e-17 64.1 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIY53484.1 - 4.1e-17 62.5 0.0 6.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY53484.1 - 1.1e-06 28.8 0.0 3.3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIY53484.1 - 8.3e-06 25.4 0.0 2.1e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KIY53484.1 - 4e-05 22.9 0.0 5.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KIY53484.1 - 4e-05 23.0 0.0 5.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY53484.1 - 0.00011 21.9 0.0 0.00039 20.1 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY53484.1 - 0.00035 19.4 0.0 0.00053 18.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KIY53484.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIY53484.1 - 0.019 14.2 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 KIY53484.1 - 0.024 14.3 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KIY53484.1 - 0.037 13.3 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY53484.1 - 0.053 14.1 0.1 0.37 11.4 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ribonuc_red_sm PF00268.21 KIY53485.1 - 1.4e-119 398.7 1.0 1.6e-119 398.5 1.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 KIY53485.1 - 0.17 12.7 0.0 0.33 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) ANAPC4_WD40 PF12894.7 KIY53486.1 - 0.00052 20.3 0.0 0.34 11.2 0.0 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY53486.1 - 0.041 14.8 0.0 2.1 9.3 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat SET PF00856.28 KIY53487.1 - 3.2e-14 53.7 0.0 1.9e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 SET domain GST_N_3 PF13417.6 KIY53488.1 - 8e-14 51.8 0.1 1.3e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY53488.1 - 3e-10 40.2 0.0 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY53488.1 - 1.5e-07 31.3 0.1 3.6e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIY53488.1 - 1.1e-06 28.8 0.0 2.5e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KIY53488.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 KIY53488.1 - 0.0005 20.2 0.0 0.00095 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY53488.1 - 0.00078 19.6 0.0 0.0018 18.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KIY53488.1 - 0.015 15.9 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CBFD_NFYB_HMF PF00808.23 KIY53489.1 - 3.7e-27 94.4 0.4 4.5e-27 94.1 0.4 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY53489.1 - 0.00012 22.4 0.0 0.00013 22.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KIY53489.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KIY53489.1 - 0.0068 16.5 0.0 0.008 16.3 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAN_3 PF08277.12 KIY53489.1 - 0.067 13.0 0.1 0.095 12.5 0.1 1.2 1 0 0 1 1 1 0 PAN-like domain Bromo_TP PF07524.13 KIY53489.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated RNA_lig_T4_1 PF09511.10 KIY53490.1 - 7.2e-84 281.0 0.0 1.4e-83 280.1 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KIY53490.1 - 4.5e-25 88.7 0.1 8.4e-25 87.8 0.1 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KIY53490.1 - 1.3e-23 83.8 0.0 2.4e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 KIY53490.1 - 0.0041 17.7 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KIY53490.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate kinase AAA PF00004.29 KIY53490.1 - 0.17 12.3 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cep57_MT_bd PF06657.13 KIY53491.1 - 0.051 14.0 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Uds1 PF15456.6 KIY53491.1 - 0.053 13.7 1.0 0.13 12.4 1.0 1.6 1 0 0 1 1 1 0 Up-regulated During Septation HrpB7 PF09486.10 KIY53491.1 - 0.49 10.8 7.4 3.4 8.1 0.2 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 KIY53491.1 - 0.52 11.0 1.6 6.3 7.5 0.1 2.8 3 0 0 3 3 3 0 SlyX WD40 PF00400.32 KIY53493.1 - 7.2e-08 33.0 3.9 0.13 13.2 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat SRA1 PF07304.11 KIY53493.1 - 2.1e-05 24.3 0.0 2.1e-05 24.3 0.0 3.0 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 KIY53493.1 - 0.00037 20.3 0.1 0.00078 19.2 0.1 1.6 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 AAA_28 PF13521.6 KIY53495.1 - 2.5e-18 66.9 0.5 4.8e-18 65.9 0.5 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY53495.1 - 3.2e-05 24.4 0.0 6.4e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIY53495.1 - 0.00014 22.4 0.0 0.00028 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY53495.1 - 0.00019 21.2 0.0 0.00056 19.7 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KIY53495.1 - 0.0017 18.4 0.0 0.0045 17.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KIY53495.1 - 0.0026 18.1 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase MobB PF03205.14 KIY53495.1 - 0.0035 17.2 0.0 0.0067 16.3 0.0 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 KIY53495.1 - 0.0041 17.2 0.0 0.018 15.1 0.0 2.0 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 KIY53495.1 - 0.0043 17.6 0.0 0.012 16.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KIY53495.1 - 0.0049 17.2 0.2 0.015 15.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KIY53495.1 - 0.0057 16.5 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA PF00004.29 KIY53495.1 - 0.0068 16.8 0.0 0.013 16.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KIY53495.1 - 0.0075 16.0 0.1 0.015 15.0 0.1 1.9 1 1 0 1 1 1 1 Cytidylate kinase PduV-EutP PF10662.9 KIY53495.1 - 0.0078 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KIY53495.1 - 0.008 16.1 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 NTPase G-alpha PF00503.20 KIY53495.1 - 0.012 14.8 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit CLP1_P PF16575.5 KIY53495.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 KIY53495.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 KIY53495.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KIY53495.1 - 0.017 15.3 0.0 0.066 13.4 0.0 2.1 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KIY53495.1 - 0.019 15.1 0.2 0.041 14.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KIY53495.1 - 0.022 14.4 0.1 0.056 13.1 0.0 1.7 2 1 0 2 2 2 0 Thymidylate kinase SRP54 PF00448.22 KIY53495.1 - 0.027 14.1 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 KIY53495.1 - 0.028 13.5 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein dNK PF01712.19 KIY53495.1 - 0.032 14.1 0.2 0.33 10.8 0.2 2.3 1 1 0 1 1 1 0 Deoxynucleoside kinase ATPase_2 PF01637.18 KIY53495.1 - 0.039 13.8 0.0 0.094 12.6 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KIY53495.1 - 0.044 13.4 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KIY53495.1 - 0.051 13.0 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KIY53495.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 KIY53495.1 - 0.073 12.8 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KIY53495.1 - 0.092 12.0 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 KIY53495.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase AAA_26 PF13500.6 KIY53495.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain MKT1_C PF12246.8 KIY53495.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_24 PF13479.6 KIY53495.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TMEM237 PF15383.6 KIY53496.1 - 0.0069 15.5 4.7 0.0086 15.2 4.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 237 FmiP_Thoc5 PF09766.9 KIY53498.1 - 0.17 11.1 1.5 0.25 10.6 0.8 1.6 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF3827 PF12877.7 KIY53498.1 - 6.6 5.0 14.9 0.015 13.7 2.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3827) MDM10 PF12519.8 KIY53499.1 - 4.6e-91 306.0 0.0 2.4e-79 267.4 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Robl_LC7 PF03259.17 KIY53500.1 - 3.7e-05 23.4 0.0 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 Roadblock/LC7 domain Ribosomal_L33 PF00471.20 KIY53501.1 - 5.4e-07 30.0 0.0 9.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L33 ELP6 PF09807.9 KIY53502.1 - 2.6e-11 43.4 0.1 2.8e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 Elongation complex protein 6 ATPase PF06745.13 KIY53502.1 - 0.00023 20.6 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 KaiC MEDS PF14417.6 KIY53502.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain F-box-like_2 PF13013.6 KIY53502.1 - 0.0046 16.9 0.2 0.075 13.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like domain Elong_Iki1 PF10483.9 KIY53502.1 - 0.033 13.7 0.2 0.043 13.3 0.2 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 tRNA-synt_1c PF00749.21 KIY53503.1 - 2.2e-83 279.8 0.0 2.8e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MASE2 PF05230.11 KIY53504.1 - 8.7 6.5 14.2 1.4 9.1 6.8 2.9 1 1 2 3 3 3 0 MASE2 domain zf-RVT PF13966.6 KIY53505.1 - 0.00068 20.3 0.1 0.0018 18.9 0.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase MCR_alpha_N PF02745.15 KIY53505.1 - 0.032 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain RibD_C PF01872.17 KIY53506.1 - 3.1e-11 43.5 0.0 3.9e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain IMP2_C PF18591.1 KIY53506.1 - 0.073 13.0 0.2 6.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) C-terminal domain PDH_E1_M PF17831.1 KIY53506.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain Amnionless PF14828.6 KIY53507.1 - 0.03 13.2 0.1 0.058 12.2 0.1 1.3 1 1 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 KIY53507.1 - 0.056 14.3 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gly-zipper_Omp PF13488.6 KIY53507.1 - 0.66 10.0 6.9 0.21 11.6 3.6 1.8 2 0 0 2 2 2 0 Glycine zipper Peptidase_S8 PF00082.22 KIY53508.1 - 5.7e-33 114.4 1.8 7.8e-33 114.0 1.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KIY53508.1 - 6.9e-26 90.1 0.9 1.3e-25 89.2 0.9 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KIY53508.1 - 0.035 14.9 2.2 0.18 12.6 0.5 2.7 2 1 0 2 2 2 0 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KIY53508.1 - 0.082 13.4 0.0 0.22 12.0 0.0 1.6 2 0 0 2 2 2 0 N-terminal of Subtilase family Fungal_trans PF04082.18 KIY53509.1 - 9e-15 54.4 0.9 3.9e-14 52.3 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 KIY53510.1 - 7e-66 222.9 0.0 8.6e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FANCF PF11107.8 KIY53510.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) DUF4446 PF14584.6 KIY53510.1 - 0.25 11.3 0.1 0.64 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Isochorismatase PF00857.20 KIY53511.1 - 1.6e-29 103.3 0.0 1.9e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Chs7 PF12271.8 KIY53512.1 - 7e-67 225.8 10.5 1.4e-64 218.2 10.5 2.8 1 1 0 1 1 1 1 Chitin synthase export chaperone YIF1 PF03878.15 KIY53512.1 - 0.13 11.7 4.6 0.92 9.0 0.8 2.3 2 0 0 2 2 2 0 YIF1 RNA_pol_L_2 PF13656.6 KIY53513.1 - 2.3e-25 88.2 0.0 2.9e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KIY53513.1 - 1.6e-12 46.6 0.0 2.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 KIY53513.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Rio2, N-terminal Glyco_hydro_7 PF00840.20 KIY53514.1 - 3.3e-12 45.9 0.1 3.6e-12 45.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Mod_r PF07200.13 KIY53515.1 - 2.5e-42 144.4 5.2 5.5e-42 143.3 5.2 1.5 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 KIY53515.1 - 0.00037 20.6 3.0 0.0013 18.8 3.1 1.8 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion JAKMIP_CC3 PF16034.5 KIY53515.1 - 0.14 12.1 5.3 0.27 11.2 0.1 2.1 2 0 0 2 2 2 0 JAKMIP CC3 domain GPI-anchored PF10342.9 KIY53516.1 - 1.5e-08 35.3 4.0 1.5e-08 35.3 4.0 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DDHD PF02862.17 KIY53516.1 - 0.12 12.5 3.8 0.16 12.1 3.8 1.1 1 0 0 1 1 1 0 DDHD domain Gal_mutarotas_3 PF18080.1 KIY53516.1 - 0.29 11.1 13.2 0.38 10.7 13.2 1.0 1 0 0 1 1 1 0 Galactose mutarotase-like fold domain BAF1_ABF1 PF04684.13 KIY53516.1 - 1.6 7.7 5.3 1.8 7.5 5.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Apt1 PF10351.9 KIY53516.1 - 4.1 6.2 12.8 5.1 5.8 12.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 KIY53516.1 - 4.2 6.9 5.4 4.9 6.7 5.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RIFIN PF02009.16 KIY53516.1 - 8.6 6.1 5.6 9.9 5.9 5.6 1.1 1 0 0 1 1 1 0 Rifin SPX PF03105.19 KIY53516.1 - 8.7 6.1 11.4 9.6 6.0 11.4 1.1 1 0 0 1 1 1 0 SPX domain Glyco_hydro_7 PF00840.20 KIY53517.1 - 6.1e-37 127.4 5.8 1.7e-33 116.0 5.8 2.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 Ubiquitin_2 PF14560.6 KIY53519.1 - 2.8e-13 50.1 0.0 4.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LigT_PEase PF02834.16 KIY53519.1 - 0.076 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 LigT like Phosphoesterase Pkinase_fungal PF17667.1 KIY53520.1 - 2.5e-17 62.8 0.0 3.5e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RecO_C PF02565.15 KIY53520.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Recombination protein O C terminal Retrotran_gag_2 PF14223.6 KIY53522.1 - 0.00089 18.9 0.2 0.001 18.7 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Cpn60_TCP1 PF00118.24 KIY53524.1 - 4e-55 187.3 2.3 4.6e-55 187.1 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KIY53524.1 - 0.022 14.2 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF5633 PF18656.1 KIY53524.1 - 0.13 12.2 2.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5633) BNR_4 PF15892.5 KIY53527.1 - 2.8e-33 115.5 0.0 3.8e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member CCDC24 PF15669.5 KIY53529.1 - 0.029 14.2 1.9 0.046 13.6 1.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family CAP_N PF01213.19 KIY53529.1 - 0.034 13.6 2.8 0.05 13.1 2.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4614 PF15391.6 KIY53529.1 - 0.073 13.1 4.7 0.12 12.4 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Sigma70_r1_1 PF03979.14 KIY53529.1 - 0.079 13.0 1.7 1.3 9.1 0.5 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 TFIIF_alpha PF05793.12 KIY53529.1 - 0.17 10.5 5.8 0.22 10.0 5.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 KIY53529.1 - 0.22 9.8 2.1 0.28 9.4 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec3_C PF09763.9 KIY53529.1 - 0.34 9.2 1.1 0.45 8.8 1.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 HhH-GPD PF00730.25 KIY53531.1 - 8.6e-09 35.8 0.0 1.1e-08 35.4 0.0 1.4 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 KIY53531.1 - 0.037 14.6 0.0 0.068 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Hist_deacetyl PF00850.19 KIY53532.1 - 1e-45 156.5 0.1 1.4e-45 156.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain zf-MYND PF01753.18 KIY53534.1 - 1.4e-08 34.6 20.1 2.4e-08 33.9 20.1 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KIY53534.1 - 0.00015 21.5 11.8 0.00029 20.6 11.8 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 KIY53534.1 - 1.9 8.7 10.0 3.2 8.0 10.0 1.4 1 0 0 1 1 1 0 B-box zinc finger Ecl1 PF12855.7 KIY53534.1 - 2.1 9.5 8.8 3.1 8.9 8.8 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins GPP34 PF05719.11 KIY53535.1 - 2.9e-63 213.6 0.4 3.6e-63 213.3 0.4 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) 3HCDH_N PF02737.18 KIY53535.1 - 0.075 12.9 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dynamin_N PF00350.23 KIY53536.1 - 2e-29 102.8 0.0 5.5e-29 101.4 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KIY53536.1 - 1.6e-25 90.0 0.0 2.1e-24 86.3 0.0 2.1 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 KIY53536.1 - 1e-08 35.2 1.1 2.5e-08 34.0 0.0 2.3 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY53536.1 - 4.1e-05 23.6 0.0 0.00016 21.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KIY53536.1 - 0.15 11.8 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2125 PF09898.9 KIY53536.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) ABC_tran PF00005.27 KIY53536.1 - 0.16 12.5 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Abhydrolase_6 PF12697.7 KIY53537.1 - 9.5e-11 42.7 1.2 9.5e-11 42.7 1.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY53537.1 - 2e-08 33.8 0.0 2.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY53537.1 - 7.6e-08 32.3 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KIY53537.1 - 5.4e-06 26.4 0.0 9.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KIY53537.1 - 4.9e-05 23.5 0.0 8.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF818 PF05677.12 KIY53537.1 - 0.0068 15.4 0.0 0.0097 14.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DUF1057 PF06342.12 KIY53537.1 - 0.019 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.25 KIY53537.1 - 0.031 14.1 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Chlorophyllase2 PF12740.7 KIY53537.1 - 0.081 11.8 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme Hist_deacetyl PF00850.19 KIY53541.1 - 1.3e-24 87.3 0.3 1.8e-24 86.8 0.3 1.1 1 0 0 1 1 1 1 Histone deacetylase domain F-box-like PF12937.7 KIY53542.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like OPT PF03169.15 KIY53543.1 - 9.9e-08 31.1 0.1 1.1e-07 30.9 0.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 KIY53544.1 - 4.3e-15 55.4 11.2 4.8e-15 55.2 11.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 2OG-FeII_Oxy_2 PF13532.6 KIY53548.1 - 1.2e-16 61.5 0.0 1.4e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GLTP PF08718.11 KIY53549.1 - 6.2e-37 127.2 0.0 7.5e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PsiE PF06146.12 KIY53549.1 - 0.2 12.0 0.8 0.39 11.1 0.8 1.5 1 0 0 1 1 1 0 Phosphate-starvation-inducible E NAD_binding_4 PF07993.12 KIY53550.1 - 2.1e-25 89.4 0.0 3.3e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIY53550.1 - 1.8e-19 69.6 0.1 4e-18 65.2 0.1 2.2 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIY53550.1 - 1e-08 35.0 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY53550.1 - 3.5e-06 27.3 0.0 8.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Vpu PF00558.19 KIY53551.1 - 0.41 10.5 1.6 0.68 9.7 1.6 1.2 1 0 0 1 1 1 0 Vpu protein G-patch PF01585.23 KIY53552.1 - 1.9e-05 24.4 0.2 0.00012 21.9 0.2 2.2 2 0 0 2 2 2 1 G-patch domain GPI-anchored PF10342.9 KIY53553.1 - 0.00053 20.7 0.1 0.0017 19.1 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4244 PF14029.6 KIY53555.1 - 0.03 13.8 0.1 0.067 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) TPR_9 PF13371.6 KIY53556.1 - 0.033 14.3 2.0 0.7 10.1 0.6 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Takusan PF04822.13 KIY53557.1 - 0.13 12.1 0.5 0.43 10.5 0.3 1.9 2 0 0 2 2 2 0 Takusan DUF737 PF05300.11 KIY53557.1 - 0.19 12.1 2.8 0.3 11.4 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) OPT PF03169.15 KIY53558.1 - 1.8e-182 608.3 64.2 2e-182 608.1 64.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Myc_target_1 PF15179.6 KIY53559.1 - 0.0056 16.6 2.7 0.049 13.5 2.7 2.0 1 1 0 1 1 1 1 Myc target protein 1 DUF3042 PF11240.8 KIY53559.1 - 1.4 9.0 3.6 2.6 8.1 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) zf-HC2 PF13490.6 KIY53560.1 - 0.039 14.2 0.6 0.099 12.9 0.6 1.7 1 0 0 1 1 1 0 Putative zinc-finger Methuselah_N PF06652.12 KIY53560.1 - 0.13 12.1 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Methuselah N-terminus Egh16-like PF11327.8 KIY53561.1 - 2.9e-35 122.3 3.4 2.9e-35 122.3 3.4 2.2 2 0 0 2 2 2 1 Egh16-like virulence factor FliD_N PF02465.18 KIY53561.1 - 0.56 10.9 9.6 0.43 11.3 2.4 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus UBN_AB PF14075.6 KIY53562.1 - 8.8e-43 146.5 0.1 1.5e-42 145.8 0.1 1.3 1 0 0 1 1 1 1 Ubinuclein conserved middle domain HUN PF08729.10 KIY53562.1 - 3.8e-14 52.4 0.7 1.2e-13 50.8 0.7 1.9 1 0 0 1 1 1 1 HPC2 and ubinuclein domain GATA PF00320.27 KIY53563.1 - 3.1e-25 87.5 19.7 4.8e-15 54.9 3.5 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 KIY53563.1 - 3e-11 42.9 0.7 3e-11 42.9 0.7 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 KIY53563.1 - 0.022 14.9 5.4 2.1 8.5 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 KIY53563.1 - 0.09 13.0 5.8 0.76 10.0 0.8 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Integrase_Zn PF02022.19 KIY53563.1 - 0.095 12.7 0.2 0.38 10.8 0.2 2.1 1 0 0 1 1 1 0 Integrase Zinc binding domain eIF-5_eIF-2B PF01873.17 KIY53563.1 - 0.16 11.9 5.9 4.9 7.1 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KIY53563.1 - 0.42 10.2 7.2 0.51 9.9 0.8 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 KIY53563.1 - 0.63 10.4 2.1 1.1 9.5 0.8 2.1 2 0 0 2 2 2 0 zinc-ribbon zf-ribbon_3 PF13248.6 KIY53563.1 - 2.2 7.8 6.0 3.9 7.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-RRN7 PF11781.8 KIY53563.1 - 2.6 7.8 7.7 0.15 11.8 0.4 2.7 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 KIY53563.1 - 2.8 8.0 5.7 1.2 9.1 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KIY53563.1 - 3.9 7.5 9.3 2.4 8.2 2.1 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Elf1 PF05129.13 KIY53563.1 - 4.5 7.4 5.7 7.1 6.7 0.1 2.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.7 KIY53563.1 - 8.5 6.5 10.2 88 3.2 10.3 2.5 1 1 0 1 1 1 0 Double zinc ribbon APH PF01636.23 KIY53564.1 - 2.6e-06 27.6 1.1 4e-06 26.9 1.1 1.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2937 PF11157.8 KIY53564.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Kdo PF06293.14 KIY53564.1 - 0.027 13.9 0.3 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC2 PF13490.6 KIY53565.1 - 0.13 12.6 0.3 0.44 10.8 0.1 1.9 2 0 0 2 2 2 0 Putative zinc-finger AAA_22 PF13401.6 KIY53567.1 - 0.092 13.0 0.3 8.1 6.7 0.0 2.8 2 1 1 3 3 3 0 AAA domain EKLF_TAD2 PF16833.5 KIY53568.1 - 0.012 15.6 1.0 0.038 14.0 1.0 1.8 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 2 Methuselah_N PF06652.12 KIY53569.1 - 0.0069 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Methuselah N-terminus zf-HC2 PF13490.6 KIY53569.1 - 0.089 13.1 0.4 0.24 11.7 0.4 1.7 1 0 0 1 1 1 0 Putative zinc-finger AAA_16 PF13191.6 KIY53570.1 - 0.13 12.7 0.0 0.54 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain CCT PF06203.14 KIY53571.1 - 2 8.5 6.3 7.2 6.8 4.4 2.7 3 0 0 3 3 3 0 CCT motif OPT PF03169.15 KIY53572.1 - 4.6e-10 38.8 0.3 4.8e-10 38.7 0.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_79C PF16862.5 KIY53575.1 - 1e-15 58.5 2.6 1.1e-15 58.4 0.1 2.4 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain DivIC PF04977.15 KIY53576.1 - 0.057 13.2 0.6 0.057 13.2 0.6 3.8 2 1 1 3 3 3 0 Septum formation initiator DUF1176 PF06674.11 KIY53576.1 - 0.07 12.6 2.7 0.056 12.9 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1176) DUF3545 PF12065.8 KIY53576.1 - 0.64 10.1 7.2 4.5 7.4 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Exonuc_VII_L PF02601.15 KIY53576.1 - 0.93 9.0 8.5 1.5 8.4 8.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 KIY53576.1 - 1.2 9.2 25.8 0.5 10.4 10.2 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KIY53576.1 - 3.2 7.9 25.9 11 6.2 14.2 3.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MCC-bdg_PDZ PF10506.9 KIY53576.1 - 3.4 7.8 7.4 9.8 6.3 1.9 2.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome APG6_N PF17675.1 KIY53576.1 - 3.4 8.2 21.9 8.5 6.9 12.3 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 KIY53576.1 - 3.5 6.4 26.5 4.5 6.1 11.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Glyco_hydro_79C PF16862.5 KIY53577.1 - 3.2e-17 63.3 0.1 1e-16 61.7 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Egh16-like PF11327.8 KIY53578.1 - 7.7e-36 124.2 1.4 8.6e-36 124.1 1.4 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor Egh16-like PF11327.8 KIY53579.1 - 6.4e-35 121.2 1.1 7.4e-35 121.0 1.1 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor DUF4402 PF14352.6 KIY53579.1 - 0.019 15.6 2.0 0.033 14.8 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Glyco_transf_5 PF08323.11 KIY53580.1 - 3.9e-14 52.9 0.1 7e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.24 KIY53580.1 - 1.7e-12 47.6 0.6 1.7e-12 47.6 0.6 3.1 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.20 KIY53580.1 - 4.8e-07 29.5 0.0 8.8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Egh16-like PF11327.8 KIY53581.1 - 7.3e-35 121.0 2.2 8.5e-35 120.8 2.2 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor DUF4402 PF14352.6 KIY53581.1 - 0.026 15.2 3.2 0.042 14.5 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) HNH_2 PF13391.6 KIY53582.1 - 4.3e-06 26.8 0.1 8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease NUDIX PF00293.28 KIY53583.1 - 1.1e-09 38.4 0.0 1.3e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_3 PF07859.13 KIY53583.1 - 0.048 13.5 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.25 KIY53584.1 - 3.3e-19 69.3 0.0 3.6e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIY53584.1 - 5.5e-05 22.6 0.0 6.2e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 KIY53584.1 - 0.00015 21.2 0.0 0.00015 21.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY53584.1 - 0.0034 16.2 0.0 0.0036 16.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY53584.1 - 0.024 14.0 0.1 0.028 13.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY53584.1 - 0.059 13.3 0.4 0.074 13.0 0.4 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1678 PF07913.11 KIY53587.1 - 0.21 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) NUDIX-like PF09296.11 KIY53590.1 - 0.0019 18.8 0.0 0.0026 18.4 0.0 1.2 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain CMAS PF02353.20 KIY53592.1 - 1.7e-09 37.4 0.0 2e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FAD_binding_3 PF01494.19 KIY53598.1 - 2.1e-67 227.9 0.0 4e-67 226.9 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIY53598.1 - 0.00042 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY53598.1 - 0.0026 17.1 0.5 0.21 10.8 0.0 3.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY53598.1 - 0.046 12.4 0.1 0.21 10.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KIY53598.1 - 0.052 12.6 0.2 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KIY53598.1 - 0.074 13.6 0.0 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY53598.1 - 0.079 12.5 1.2 0.61 9.6 0.1 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIY53598.1 - 0.13 11.5 0.1 0.24 10.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY53598.1 - 0.14 11.0 0.7 0.25 10.1 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Ribosomal_S2 PF00318.20 KIY53599.1 - 7.1e-28 97.3 0.8 1.7e-15 56.8 0.3 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KIY53599.1 - 1.7e-07 32.5 11.4 3.4e-07 31.5 11.4 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus OTT_1508_deam PF14441.6 KIY53601.1 - 0.015 15.2 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase NOG1_N PF17835.1 KIY53602.1 - 3e-49 167.1 0.8 3e-49 167.1 0.8 1.8 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KIY53602.1 - 1.6e-28 98.4 3.6 4.3e-28 97.1 3.6 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KIY53602.1 - 7.1e-27 93.0 0.0 1.5e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KIY53602.1 - 2.2e-17 63.2 0.0 6.3e-17 61.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY53602.1 - 1.7e-10 40.7 0.0 4.9e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIY53602.1 - 0.00077 19.4 0.1 0.49 10.3 0.0 3.0 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KIY53602.1 - 0.0052 16.9 0.2 1.7 8.7 0.0 3.0 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 KIY53602.1 - 0.063 13.7 0.1 1.4 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Sushi_2 PF09014.10 KIY53602.1 - 0.077 12.9 0.4 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain AIG1 PF04548.16 KIY53602.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 AIG1 family RR_TM4-6 PF06459.12 KIY53602.1 - 1.5 8.6 7.5 2.5 7.9 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tfb2 PF03849.14 KIY53603.1 - 2.3e-128 428.1 0.0 3.2e-128 427.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KIY53603.1 - 5.7e-27 93.9 0.1 9.9e-27 93.2 0.1 1.4 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KIY53603.1 - 0.00047 20.3 0.0 0.002 18.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain IBR PF01485.21 KIY53604.1 - 5.7e-14 52.1 39.0 3.5e-09 36.8 16.8 4.1 3 2 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KIY53604.1 - 0.00017 21.4 2.0 0.00017 21.4 2.0 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY53604.1 - 0.0031 17.3 7.5 0.0031 17.3 7.5 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY53604.1 - 0.01 15.9 4.1 0.01 15.9 4.1 4.0 3 1 0 3 3 3 0 RING-type zinc-finger zf-RING_2 PF13639.6 KIY53604.1 - 3.4 8.1 32.5 0.37 11.2 7.7 3.8 3 0 0 3 3 3 0 Ring finger domain Zn_Tnp_IS91 PF14319.6 KIY53604.1 - 7.5 6.7 18.2 0.83 9.7 1.7 3.7 3 0 0 3 3 3 0 Transposase zinc-binding domain CNH PF00780.22 KIY53605.1 - 1.8e-13 50.8 0.0 3.9e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 CNH domain E1_dh PF00676.20 KIY53606.1 - 3.8e-108 361.0 0.0 4.5e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KIY53606.1 - 0.0047 16.2 0.0 0.0085 15.3 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KIY53606.1 - 0.021 14.6 1.9 0.025 14.4 0.5 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FAD_binding_3 PF01494.19 KIY53607.1 - 3.9e-71 240.1 0.0 5.1e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KIY53607.1 - 4.7e-24 85.3 0.0 8.7e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KIY53607.1 - 0.00022 20.1 0.0 0.00034 19.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KIY53607.1 - 0.0024 17.1 0.0 0.0054 16.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY53607.1 - 0.0026 16.9 0.1 0.013 14.6 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIY53607.1 - 0.008 16.4 0.0 0.037 14.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY53607.1 - 0.024 15.2 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KIY53607.1 - 0.053 12.0 0.0 0.074 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_binding_2 PF00890.24 KIY53607.1 - 0.091 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Rossmann-like PF10727.9 KIY53607.1 - 0.17 11.7 0.0 1.1 9.1 0.0 2.3 3 0 0 3 3 3 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KIY53607.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KIY53608.1 - 2.7e-69 234.1 0.0 3.6e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY53608.1 - 0.00026 21.1 0.0 0.00088 19.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY53608.1 - 0.006 15.9 1.7 0.28 10.4 0.0 3.7 5 0 0 5 5 5 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY53608.1 - 0.058 13.9 0.0 0.61 10.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY53608.1 - 0.059 12.2 0.8 0.079 11.8 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 KIY53608.1 - 0.065 12.8 0.8 0.6 9.6 0.2 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase AhpC-TSA PF00578.21 KIY53608.1 - 0.13 12.2 0.0 3 7.8 0.0 2.3 1 1 0 1 1 1 0 AhpC/TSA family HI0933_like PF03486.14 KIY53608.1 - 0.13 10.9 0.1 0.25 10.0 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIY53608.1 - 0.17 11.1 0.2 0.31 10.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KIY53612.1 - 7.9e-31 107.4 0.0 2.8e-29 102.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53612.1 - 3.3e-10 39.7 0.0 3.1e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 KIY53612.1 - 0.068 12.8 0.1 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KIY53612.1 - 1 8.0 3.2 1.1 8.0 1.0 1.8 1 1 1 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 KIY53613.1 - 2.3e-16 59.9 0.3 2e-15 56.9 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53613.1 - 1.6e-09 37.5 0.1 6.9e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 KIY53613.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_3_C PF01915.22 KIY53614.1 - 1.7e-60 204.5 0.0 2.9e-60 203.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY53614.1 - 1.9e-44 152.3 0.0 3.4e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY53614.1 - 1.1e-23 83.1 0.7 2.4e-23 82.0 0.7 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KIY53614.1 - 2.5e-14 53.3 0.0 4.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain SIS PF01380.22 KIY53614.1 - 0.098 12.5 0.5 0.57 10.0 0.5 2.0 1 1 0 1 1 1 0 SIS domain WD40 PF00400.32 KIY53615.1 - 6.1 7.9 11.9 13 6.8 0.0 5.5 6 1 1 7 7 7 0 WD domain, G-beta repeat UPRTase PF14681.6 KIY53616.1 - 5.6e-76 254.6 0.0 7.1e-76 254.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KIY53616.1 - 0.00013 21.6 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain START PF01852.19 KIY53618.1 - 5.7e-17 61.8 0.5 3e-08 33.3 0.2 3.3 3 0 0 3 3 3 2 START domain DEC-1_N PF04625.13 KIY53618.1 - 3.1 6.7 7.7 6.7 5.6 7.7 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Sensor PF13796.6 KIY53619.1 - 3.5e-06 27.2 13.4 0.00018 21.6 13.4 2.3 1 1 0 1 1 1 1 Putative sensor HSP70 PF00012.20 KIY53620.1 - 1.4e-156 522.2 0.1 1.4e-156 522.2 0.1 2.4 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KIY53620.1 - 1.9e-08 33.5 0.1 6.2e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Apolipoprotein PF01442.18 KIY53620.1 - 0.019 14.9 6.3 5.6 6.8 0.0 3.7 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain HsbA PF12296.8 KIY53620.1 - 0.099 13.1 0.1 29 5.1 0.0 2.7 2 0 0 2 2 2 0 Hydrophobic surface binding protein A IL6 PF00489.17 KIY53620.1 - 0.18 11.4 0.4 19 4.7 0.0 2.5 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family tRNA-synt_2 PF00152.20 KIY53621.1 - 6.8e-76 255.3 0.0 8.7e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY53621.1 - 4e-13 49.1 0.0 5.1e-12 45.6 0.0 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIY53621.1 - 3e-08 33.5 0.0 0.00043 19.9 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) GMC_oxred_N PF00732.19 KIY53622.1 - 2.3e-52 178.2 0.0 3.2e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY53622.1 - 1.5e-31 109.9 0.0 3.2e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY53622.1 - 1.2e-05 25.4 0.1 3.1e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIY53622.1 - 0.00021 20.5 0.1 0.00042 19.5 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIY53622.1 - 0.0011 18.3 0.1 0.0057 15.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY53622.1 - 0.0011 18.6 2.8 0.0022 17.6 0.6 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY53622.1 - 0.0023 17.1 0.7 0.019 14.1 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KIY53622.1 - 0.003 16.8 1.0 0.0085 15.4 0.2 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KIY53622.1 - 0.0032 16.2 0.1 0.012 14.3 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KIY53622.1 - 0.011 15.0 0.2 0.03 13.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY53622.1 - 0.057 12.3 0.2 0.091 11.6 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase ANAPC4_WD40 PF12894.7 KIY53623.1 - 3.6e-20 72.0 1.0 8.4e-07 29.2 0.1 4.4 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY53623.1 - 2.8e-18 65.9 10.5 4.3e-06 27.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 KIY53623.1 - 7.5e-06 26.0 0.1 0.082 12.8 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A UTP25 PF06862.12 KIY53624.1 - 6.5e-155 516.5 0.0 7.4e-155 516.3 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KIY53624.1 - 0.00045 20.0 0.0 0.0061 16.3 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Microtub_bd PF16796.5 KIY53624.1 - 0.04 13.9 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Microtubule binding CAP59_mtransfer PF11735.8 KIY53625.1 - 1.3e-62 211.6 0.0 1.7e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Autophagy_N PF03986.13 KIY53627.1 - 2.7e-41 140.7 1.5 8.9e-41 139.0 0.0 2.1 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KIY53627.1 - 2.5e-18 66.4 0.4 5.3e-18 65.3 0.4 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KIY53627.1 - 1.6e-12 46.7 1.8 3e-12 45.8 1.8 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal IFT43 PF15305.6 KIY53627.1 - 0.066 13.4 0.3 0.066 13.4 0.3 2.7 2 1 1 3 3 3 0 Intraflagellar transport protein 43 PLA2_B PF01735.18 KIY53628.1 - 5.3e-115 384.6 0.2 6.5e-115 384.3 0.2 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain zf-LYAR PF08790.11 KIY53629.1 - 5.3e-15 55.0 3.2 9.2e-15 54.2 3.2 1.4 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 KIY53629.1 - 0.042 14.2 0.1 0.098 13.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding peroxidase PF00141.23 KIY53630.1 - 1.1e-45 156.2 0.0 1.6e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Arrestin_N PF00339.29 KIY53632.1 - 4.3e-10 39.8 0.0 8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KIY53632.1 - 5.4e-10 39.8 0.2 2.1e-07 31.5 0.1 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KIY53632.1 - 0.0015 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like DSHCT PF08148.12 KIY53632.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain ATP-synt_I PF03899.15 KIY53633.1 - 0.0012 19.2 1.8 0.0012 19.2 1.8 2.5 2 0 0 2 2 2 1 ATP synthase I chain DUF3487 PF11990.8 KIY53633.1 - 2.2 8.2 6.4 2.1 8.2 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) S_4TM PF18159.1 KIY53633.1 - 2.7 7.2 4.2 1.4 8.1 0.5 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Nramp PF01566.18 KIY53634.1 - 5.1e-78 262.5 27.0 5.1e-78 262.5 27.0 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Pannexin_like PF12534.8 KIY53634.1 - 0.14 11.3 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 ApoLp-III PF07464.11 KIY53635.1 - 0.1 12.7 2.9 3.2 7.9 0.1 3.1 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) NPV_P10 PF05531.12 KIY53635.1 - 9.3 6.8 12.7 47 4.6 3.9 4.5 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Epimerase PF01370.21 KIY53636.1 - 9.5e-41 139.8 0.0 1.3e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY53636.1 - 3.8e-19 69.3 0.0 9.3e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glycos_transf_2 PF00535.26 KIY53636.1 - 5.2e-13 49.1 0.0 9.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 3Beta_HSD PF01073.19 KIY53636.1 - 5.7e-12 45.2 0.0 8.4e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIY53636.1 - 1.4e-08 34.9 0.0 3.2e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Glyco_tranf_2_3 PF13641.6 KIY53636.1 - 4.3e-06 26.8 0.0 1.2e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RmlD_sub_bind PF04321.17 KIY53636.1 - 8.5e-05 21.8 0.0 0.00048 19.3 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIY53636.1 - 0.00016 20.9 0.0 0.0088 15.2 0.0 2.2 1 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KIY53636.1 - 0.00062 19.0 0.0 0.045 12.9 0.1 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIY53636.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_tranf_2_2 PF10111.9 KIY53636.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NmrA PF05368.13 KIY53636.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_21 PF13506.6 KIY53636.1 - 0.11 11.9 0.1 0.49 9.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_transf_8 PF01501.20 KIY53637.1 - 9.4e-22 77.8 0.0 1.4e-20 73.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 KIY53637.1 - 1.3e-16 61.5 0.1 5e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Glyco_transf_24 PF18404.1 KIY53637.1 - 0.0028 17.1 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Ribosomal_L39 PF00832.20 KIY53638.1 - 3.9e-23 80.8 10.1 4.5e-23 80.6 10.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 KIY53638.1 - 0.028 14.0 0.5 0.028 14.0 0.5 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 RVT_1 PF00078.27 KIY53640.1 - 2.2e-05 24.1 0.0 4.4e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) KDZ PF18758.1 KIY53646.1 - 2.2e-38 132.1 0.1 3.2e-38 131.6 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIY53647.1 - 6.7e-20 71.6 0.0 9.6e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY53647.1 - 0.0064 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY53647.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY53647.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases LPD38 PF18857.1 KIY53648.1 - 0.23 11.6 0.0 0.34 11.1 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 HMG_box_2 PF09011.10 KIY53651.1 - 0.00053 20.5 0.2 0.0045 17.5 0.0 2.0 2 0 0 2 2 2 1 HMG-box domain DUF1178 PF06676.11 KIY53651.1 - 0.0013 19.1 0.3 0.0021 18.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) DUF5644 PF18712.1 KIY53651.1 - 0.072 13.1 0.2 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5644) Phage_integrase PF00589.22 KIY53653.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF2855 PF11017.8 KIY53654.1 - 9.3e-74 249.2 0.2 1.2e-40 140.3 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2855) PEX-2N PF09263.10 KIY53654.1 - 0.042 14.2 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal DDE_Tnp_4 PF13359.6 KIY53655.1 - 1.4e-09 37.8 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_ner PF04546.13 KIY53655.1 - 0.0016 18.3 0.1 0.0025 17.7 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region SR-25 PF10500.9 KIY53655.1 - 0.069 12.7 8.3 0.11 12.1 8.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDE_Tnp_1 PF01609.21 KIY53655.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain HTH_psq PF05225.16 KIY53655.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF4692 PF15763.5 KIY53655.1 - 0.12 12.9 3.0 0.22 12.0 3.0 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Cwf_Cwc_15 PF04889.12 KIY53655.1 - 1.2 8.8 9.3 0.62 9.8 7.1 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NAD_Gly3P_dh_N PF01210.23 KIY53659.1 - 1.2e-08 35.1 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cu_bind_CorA PF18252.1 KIY53659.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Copper(I)-binding protein CorA Ntox35 PF15534.6 KIY53660.1 - 0.091 13.2 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 35 HAD_2 PF13419.6 KIY53660.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KIY53661.1 - 6.5e-16 58.5 0.0 7.4e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53661.1 - 8.2e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase SPO22 PF08631.10 KIY53662.1 - 3.2e-47 161.3 11.4 2.8e-45 154.9 0.7 3.8 3 1 2 5 5 5 4 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KIY53662.1 - 1.1e-06 28.9 4.0 0.0016 18.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY53662.1 - 0.00019 21.6 2.7 0.014 15.6 0.1 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KIY53662.1 - 0.006 17.1 3.8 0.52 10.9 0.1 3.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY53662.1 - 0.033 14.3 7.0 6.1 7.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 KIY53663.1 - 1.1e-42 146.3 73.5 7.2e-33 114.0 10.5 3.2 1 1 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 KIY53663.1 - 0.0072 14.8 0.8 0.0072 14.8 0.8 3.0 3 1 1 4 4 4 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.11 KIY53663.1 - 0.025 14.1 0.5 0.025 14.1 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) CrgA PF06781.12 KIY53663.1 - 0.034 14.2 0.4 1.2 9.2 0.2 2.9 2 0 0 2 2 2 0 Cell division protein CrgA DUF3043 PF11241.8 KIY53663.1 - 4.1 7.4 5.1 0.6 10.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) OATP PF03137.20 KIY53663.1 - 4.4 5.5 15.7 0.38 9.0 0.2 3.7 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Serglycin PF04360.12 KIY53667.1 - 0.044 13.7 6.0 0.066 13.2 6.0 1.2 1 0 0 1 1 1 0 Serglycin CDC45 PF02724.14 KIY53668.1 - 0.18 10.0 0.9 0.26 9.6 0.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 KIY53668.1 - 0.54 9.9 3.1 0.9 9.2 3.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Chromo PF00385.24 KIY53669.1 - 0.029 14.3 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_2 PF08914.11 KIY53671.1 - 0.039 14.1 0.2 0.086 13.0 0.2 1.6 1 0 0 1 1 1 0 Rap1 Myb domain RVT_thumb PF06817.14 KIY53673.1 - 0.0012 18.6 0.1 0.0057 16.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase thumb domain zf-CCCH PF00642.24 KIY53674.1 - 0.017 15.1 2.0 0.039 13.9 2.0 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY53674.1 - 0.18 11.9 4.0 2.1 8.5 4.0 2.4 1 1 0 1 1 1 0 Zinc finger domain AAA-ATPase_like PF09820.9 KIY53675.1 - 1.3e-10 41.2 0.0 2.3e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 Predicted AAA-ATPase Peptidase_M16 PF00675.20 KIY53677.1 - 1.9e-52 177.2 0.4 3.2e-52 176.5 0.4 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIY53677.1 - 1.3e-41 142.7 0.0 2.4e-37 128.8 0.0 2.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_S78_2 PF14550.6 KIY53677.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative phage serine protease XkdF AAA-ATPase_like PF09820.9 KIY53678.1 - 4e-09 36.3 0.0 7.4e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Predicted AAA-ATPase DUF3040 PF11239.8 KIY53679.1 - 0.029 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF5305 PF17231.2 KIY53679.1 - 0.065 12.6 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Amnionless PF14828.6 KIY53679.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless Mid2 PF04478.12 KIY53679.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DcrB PF08786.11 KIY53680.1 - 0.5 10.5 3.5 19 5.4 0.1 2.9 2 1 1 3 3 3 0 DcrB Cornifin PF02389.15 KIY53682.1 - 2.2e-06 27.9 3.1 2.2e-06 27.9 3.1 2.3 2 1 0 2 2 2 1 Cornifin (SPRR) family PSI_integrin PF17205.3 KIY53683.1 - 0.0031 17.2 8.9 0.18 11.6 1.5 2.4 1 1 1 2 2 2 2 Integrin plexin domain Tet_JBP PF12851.7 KIY53686.1 - 0.043 13.2 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Inhibitor_I68 PF10468.9 KIY53687.1 - 0.34 11.4 4.6 0.12 12.8 1.4 1.8 2 0 0 2 2 2 0 Carboxypeptidase inhibitor I68 Hydantoinase_A PF01968.18 KIY53689.1 - 4.1e-67 226.5 0.1 5.5e-67 226.1 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIY53689.1 - 3.6e-33 114.8 0.0 5.7e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region DUF4431 PF14485.6 KIY53690.1 - 0.18 11.6 2.2 17 5.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4431) HLH PF00010.26 KIY53691.1 - 0.0055 16.6 0.0 0.0055 16.6 0.0 2.4 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Plavaka PF18759.1 KIY53692.1 - 7.7e-32 110.8 0.1 8.4e-32 110.7 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY53693.1 - 2.8e-15 56.4 0.0 5.7e-15 55.4 0.0 1.5 2 0 0 2 2 2 1 Plavaka transposase Peptidase_M20 PF01546.28 KIY53695.1 - 8.3e-23 81.2 0.0 1.2e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY53695.1 - 1.8e-07 31.1 0.0 5.4e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Adeno_IVa2 PF02456.15 KIY53695.1 - 0.17 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein F-box-like PF12937.7 KIY53696.1 - 8.4e-09 35.2 0.8 2.7e-08 33.5 0.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY53696.1 - 0.018 14.9 0.2 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 F-box domain RhoGAP PF00620.27 KIY53697.1 - 2.2e-42 144.5 0.0 6.7e-42 142.9 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 KIY53697.1 - 2.6e-11 44.0 0.0 4.5e-09 36.7 0.0 2.9 3 0 0 3 3 3 1 RasGEF domain PH_9 PF15410.6 KIY53697.1 - 1.1e-05 25.8 0.0 2.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RasGEF_N PF00618.20 KIY53697.1 - 3.1e-05 24.1 0.0 0.0004 20.6 0.0 3.0 2 1 0 2 2 2 1 RasGEF N-terminal motif PH PF00169.29 KIY53697.1 - 0.00039 20.9 0.0 0.00081 19.9 0.0 1.5 1 0 0 1 1 1 1 PH domain BRCA-2_OB1 PF09103.10 KIY53699.1 - 4.3e-35 120.3 0.0 1.1e-34 119.1 0.0 1.7 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 KIY53699.1 - 0.00023 20.9 0.1 0.00036 20.2 0.1 1.3 1 0 0 1 1 1 1 BRCA2, helical F-box-like PF12937.7 KIY53701.1 - 4e-09 36.2 1.3 1.8e-08 34.2 1.3 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY53701.1 - 9.8e-05 22.1 0.6 0.0064 16.4 0.0 3.3 3 1 0 3 3 3 1 F-box domain Fun_ATP-synt_8 PF05933.13 KIY53702.1 - 0.066 13.4 0.3 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) Mito_carr PF00153.27 KIY53703.1 - 6.3e-55 183.1 1.8 3.7e-21 74.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein KR PF08659.10 KIY53705.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 KR domain AadA_C PF18280.1 KIY53705.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Aminoglycoside adenyltransferase C-terminal domain adh_short PF00106.25 KIY53705.1 - 0.083 12.3 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase dsrm PF00035.26 KIY53706.1 - 5e-11 43.1 0.3 1e-10 42.2 0.2 1.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KIY53706.1 - 7.8e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIY53706.1 - 0.0009 19.8 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Methyltrn_RNA_4 PF09936.9 KIY53708.1 - 0.11 12.4 0.1 15 5.4 0.0 2.4 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase Bd3614-deam PF14439.6 KIY53708.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.0 2 0 0 2 2 2 0 Bd3614-like deaminase DUF3959 PF13105.6 KIY53708.1 - 0.23 10.9 1.0 0.4 10.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) HTH_29 PF13551.6 KIY53709.1 - 5.9e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KIY53709.1 - 1.6e-06 28.1 0.1 2.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIY53709.1 - 2.1e-06 27.4 0.0 4.8e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KIY53709.1 - 0.00021 21.3 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 KIY53709.1 - 0.00061 20.0 0.0 0.0013 18.9 0.0 1.5 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KIY53709.1 - 0.0057 17.2 0.0 0.19 12.3 0.0 2.2 1 1 1 2 2 2 2 Homeodomain-like domain PAX PF00292.18 KIY53709.1 - 0.024 14.6 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain Nop52 PF05997.12 KIY53709.1 - 0.18 11.6 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleolar protein,Nop52 PIH1 PF08190.12 KIY53710.1 - 1.5e-24 86.3 0.0 3e-24 85.3 0.0 1.5 2 0 0 2 2 2 1 PIH1 N-terminal domain RVT_thumb PF06817.14 KIY53713.1 - 0.00052 19.8 0.1 0.0012 18.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RRM_1 PF00076.22 KIY53714.1 - 1.1e-11 44.4 0.0 1.6e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 KIY53714.1 - 0.19 12.1 0.3 0.28 11.6 0.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G ODV-E18 PF10717.9 KIY53714.1 - 0.24 11.3 0.3 0.4 10.6 0.3 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 MFS_1 PF07690.16 KIY53716.1 - 0.0008 18.4 2.3 0.0018 17.3 2.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Med13_N PF11597.8 KIY53717.1 - 0.071 12.5 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DUF917 PF06032.12 KIY53720.1 - 3.2e-63 213.7 1.2 3.2e-63 213.7 1.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KIY53720.1 - 1.6e-28 99.8 14.5 6.3e-26 91.3 0.3 3.5 3 1 1 4 4 4 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIY53720.1 - 5e-27 94.7 0.0 5.2e-24 84.9 0.0 3.1 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.11 KIY53720.1 - 5.2e-05 22.6 0.2 0.018 14.3 0.0 2.5 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.20 KIY53720.1 - 9.2e-05 22.1 1.3 0.25 10.8 0.0 3.7 4 0 0 4 4 4 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 KIY53720.1 - 0.0056 15.3 0.4 0.033 12.8 0.0 2.1 2 0 0 2 2 2 1 MutL protein Peptidase_A4 PF01828.17 KIY53723.1 - 2.5e-77 259.1 18.0 2.9e-77 258.8 18.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family MFS_1 PF07690.16 KIY53724.1 - 8.2e-29 100.6 40.1 8.2e-29 100.6 40.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5455 PF17537.2 KIY53724.1 - 0.55 10.7 6.0 6.7 7.2 2.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5455) CBM_20 PF00686.19 KIY53725.1 - 5e-29 100.1 0.1 1.6e-28 98.5 0.1 1.9 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 KIY53725.1 - 8.8e-13 48.5 0.6 1.8e-12 47.5 0.6 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Atg31 PF09795.9 KIY53725.1 - 0.069 13.2 0.9 0.36 10.8 0.2 2.0 2 0 0 2 2 2 0 Autophagy-related protein 31 UbiA PF01040.18 KIY53726.1 - 2.8e-26 92.3 12.5 3.7e-26 91.9 12.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MBOAT_2 PF13813.6 KIY53726.1 - 0.0099 16.1 0.1 0.024 14.9 0.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family FAD_binding_3 PF01494.19 KIY53728.1 - 2.6e-10 40.1 0.0 1.7e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY53728.1 - 9.7e-10 38.1 0.0 1.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY53728.1 - 7.9e-08 32.4 0.0 3.3e-07 30.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY53728.1 - 4.1e-06 27.3 0.0 8.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY53728.1 - 9.5e-06 25.4 0.3 0.0011 18.6 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY53728.1 - 7.1e-05 21.7 0.0 0.033 12.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 KIY53728.1 - 0.00037 19.9 0.6 0.0018 17.7 0.3 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KIY53728.1 - 0.001 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KIY53728.1 - 0.0082 15.2 0.1 1.6 7.7 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIY53728.1 - 0.0083 15.4 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY53728.1 - 0.01 15.3 0.5 0.014 14.7 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY53728.1 - 0.01 14.7 0.4 0.063 12.1 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KIY53728.1 - 0.014 14.5 0.2 0.021 13.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KIY53728.1 - 0.023 13.8 0.1 0.038 13.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KIY53728.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.25 KIY53729.1 - 2.3e-63 214.0 0.0 3.4e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53729.1 - 9.2e-34 116.9 0.0 1.9e-33 115.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY53729.1 - 0.00011 21.1 0.0 0.00016 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KIY53729.1 - 0.0012 17.9 0.0 0.0026 16.9 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KIY53729.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KIY53729.1 - 0.041 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Myb_DNA-binding PF00249.31 KIY53730.1 - 2.5e-38 130.0 3.1 1.7e-12 47.3 0.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY53730.1 - 3.2e-23 81.7 0.0 2.8e-10 40.3 0.0 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 KIY53730.1 - 0.00027 21.0 0.0 1.6 8.8 0.0 3.1 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 KIY53730.1 - 0.00038 20.6 0.0 1.9 8.7 0.0 3.2 3 0 0 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.8 KIY53730.1 - 0.0046 17.0 0.0 8.4 6.6 0.0 3.0 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 KIY53730.1 - 0.0075 16.4 0.1 0.75 10.0 0.0 2.6 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 KIY53730.1 - 0.01 15.7 0.0 0.83 9.6 0.0 2.8 3 0 0 3 3 3 0 Myb DNA-binding like Myb_DNA-binding PF00249.31 KIY53731.1 - 9.8e-37 124.9 5.5 2.5e-12 46.8 0.3 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY53731.1 - 1.8e-23 82.5 0.1 3.9e-10 39.8 0.1 3.1 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIY53731.1 - 8.7e-05 22.3 0.0 0.61 10.0 0.0 2.7 2 1 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 KIY53731.1 - 0.0035 17.5 0.0 2.3 8.5 0.0 3.3 3 1 0 3 3 3 1 Rap1 Myb domain SLIDE PF09111.10 KIY53731.1 - 0.0095 15.9 0.0 4.6 7.3 0.0 3.0 1 1 2 3 3 3 1 SLIDE MADF_DNA_bdg PF10545.9 KIY53731.1 - 0.017 15.4 2.3 11 6.4 0.0 3.2 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 KIY53731.1 - 0.1 12.8 0.0 9.3 6.5 0.0 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 ACT_7 PF13840.6 KIY53732.1 - 1.2e-08 34.6 0.0 5.1e-07 29.4 0.0 2.8 2 1 0 2 2 2 1 ACT domain FAD_oxidored PF12831.7 KIY53733.1 - 0.015 14.7 0.1 0.23 10.8 0.1 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY53733.1 - 0.034 13.0 0.1 8.9 5.0 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KIY53733.1 - 0.048 12.9 0.0 0.48 9.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 KIY53735.1 - 0.0094 15.8 1.7 0.018 15.0 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIY53735.1 - 0.04 13.8 0.1 0.098 12.5 0.0 1.7 2 0 0 2 2 2 0 F-box F-box PF00646.33 KIY53735.1 - 0.068 13.1 0.3 0.068 13.1 0.3 2.9 3 0 0 3 3 3 0 F-box domain DUF3572 PF12096.8 KIY53735.1 - 0.1 12.8 0.1 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) AA_permease_2 PF13520.6 KIY53737.1 - 3.3e-25 88.8 6.1 4.1e-25 88.5 6.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4097 PF13349.6 KIY53739.1 - 0.045 13.1 0.0 1.6 8.0 0.0 2.0 1 1 0 2 2 2 0 Putative adhesin F-box-like PF12937.7 KIY53740.1 - 0.0012 18.7 1.3 0.0031 17.4 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIY53740.1 - 0.082 12.8 0.3 1.2 9.1 0.1 2.5 3 0 0 3 3 3 0 F-box F-box PF00646.33 KIY53740.1 - 0.11 12.5 0.4 0.11 12.5 0.4 2.8 3 0 0 3 3 3 0 F-box domain DUF3572 PF12096.8 KIY53740.1 - 0.15 12.3 0.1 0.63 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) Pro_isomerase PF00160.21 KIY53742.1 - 2.3e-47 161.2 0.6 2.6e-47 161.0 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Acetyltransf_1 PF00583.25 KIY53745.1 - 1.4e-06 28.5 0.0 4.7e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KIY53745.1 - 2.9e-05 24.2 0.0 0.0022 18.1 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY53745.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY53745.1 - 0.0059 17.0 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY53745.1 - 0.14 12.1 0.0 0.88 9.6 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Glycogen_syn PF05693.13 KIY53748.1 - 7.6e-22 77.6 0.8 4.6e-21 75.0 0.5 1.9 1 1 1 2 2 2 1 Glycogen synthase McyA_C PF12593.8 KIY53748.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Microcystin synthetase C terminal DDE_1 PF03184.19 KIY53749.1 - 9.4e-17 61.2 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease KRE1 PF17056.5 KIY53749.1 - 0.049 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 AA_permease_2 PF13520.6 KIY53750.1 - 3.5e-74 250.2 30.9 4.5e-74 249.8 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease TFB6 PF17110.5 KIY53751.1 - 0.007 16.1 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Zn_clus PF00172.18 KIY53757.1 - 0.035 14.2 12.9 0.46 10.6 5.5 2.5 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KIY53757.1 - 1.5 9.3 12.9 2 8.9 6.6 2.7 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region gag-asp_proteas PF13975.6 KIY53758.1 - 1e-08 35.6 0.0 1.5e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY53758.1 - 2.3e-05 25.0 0.0 3.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 KIY53758.1 - 0.0074 16.1 0.0 0.095 12.5 0.0 2.0 1 1 1 2 2 2 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 KIY53758.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Rv2175c_C PF18367.1 KIY53760.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Proteasom_PSMB PF10508.9 KIY53761.1 - 0.0062 15.1 0.3 0.0093 14.5 0.3 1.1 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Lzipper-MIP1 PF14389.6 KIY53761.1 - 0.062 13.6 0.3 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 APH PF01636.23 KIY53762.1 - 2.1e-15 57.3 0.0 2.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY53762.1 - 1.9e-06 27.6 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Y_phosphatase3 PF13350.6 KIY53763.1 - 0.01 15.8 0.1 0.016 15.1 0.1 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIY53763.1 - 0.026 14.1 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Retrotrans_gag PF03732.17 KIY53766.1 - 1.7e-06 28.2 0.2 3.6e-06 27.2 0.1 1.6 2 1 0 2 2 2 1 Retrotransposon gag protein YqfQ PF14181.6 KIY53767.1 - 1.5 8.9 4.1 2.5 8.3 4.1 1.2 1 0 0 1 1 1 0 YqfQ-like protein SDA1 PF05285.12 KIY53767.1 - 5.8 6.2 12.2 8.7 5.7 12.2 1.2 1 0 0 1 1 1 0 SDA1 Transposase_21 PF02992.14 KIY53770.1 - 5.6e-06 25.7 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 PCI PF01399.27 KIY53771.1 - 3.7e-09 37.0 0.0 5.1e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 PCI domain HTH_31 PF13560.6 KIY53771.1 - 0.11 12.8 0.4 0.26 11.6 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain 2OG-FeII_Oxy_3 PF13640.6 KIY53773.1 - 2e-09 38.2 0.0 3.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_9 PF13527.7 KIY53774.1 - 5.9e-12 45.8 0.0 2.7e-06 27.5 0.0 3.3 2 2 1 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY53774.1 - 6.5e-07 29.7 0.0 2e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY53774.1 - 1.1e-06 28.5 0.0 3e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY53774.1 - 5.2e-06 26.7 0.0 1.4e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIY53774.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_6 PF13480.7 KIY53774.1 - 0.034 14.3 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIY53774.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3808 PF10300.9 KIY53775.1 - 6.8e-79 265.8 0.0 1.1e-78 265.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KIY53775.1 - 3.7e-07 29.8 2.4 0.095 12.9 0.1 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY53775.1 - 2.8e-05 24.7 0.9 0.035 14.8 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY53775.1 - 0.00026 21.2 3.4 0.048 14.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY53775.1 - 0.056 14.3 0.9 8.9 7.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY53775.1 - 2.6 8.9 6.1 0.66 10.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Gpi16 PF04113.14 KIY53776.1 - 4.5e-139 464.4 0.0 5.5e-138 460.9 0.0 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component HMG_box PF00505.19 KIY53777.1 - 3.2e-10 40.3 1.0 3.2e-10 40.3 1.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY53777.1 - 6.6e-05 23.4 0.2 6.6e-05 23.4 0.2 1.8 2 0 0 2 2 2 1 HMG-box domain zf-U11-48K PF05253.12 KIY53778.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger DUF1192 PF06698.11 KIY53778.1 - 0.02 14.9 3.4 0.08 13.0 3.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) HA2 PF04408.23 KIY53779.1 - 8.9e-19 67.8 2.3 9.6e-19 67.7 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY53779.1 - 2.1e-13 50.6 0.0 8.1e-13 48.7 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIY53779.1 - 4.5e-10 39.7 0.0 1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KIY53779.1 - 3e-07 30.4 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY53779.1 - 0.00019 21.7 0.2 0.00095 19.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY53779.1 - 0.0032 17.2 0.1 0.03 14.0 0.1 2.4 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 KIY53779.1 - 0.0044 16.5 0.1 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 KIY53779.1 - 0.02 14.5 0.0 0.061 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIY53779.1 - 0.044 14.1 0.1 0.14 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIY53779.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 KIY53779.1 - 0.066 13.2 0.0 6 6.8 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KIY53779.1 - 0.082 12.2 0.2 0.2 11.0 0.2 1.6 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 KIY53779.1 - 0.089 11.8 0.1 0.21 10.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Mlf1IP PF10248.9 KIY53779.1 - 0.095 12.7 0.5 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Glyco_hydro_61 PF03443.14 KIY53780.1 - 5.8e-09 36.2 0.5 1e-08 35.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 NUDIX PF00293.28 KIY53781.1 - 3.3e-09 36.9 0.0 5.5e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain MFS_1 PF07690.16 KIY53783.1 - 7.1e-14 51.5 45.5 3.1e-10 39.5 21.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyanate_lyase PF02560.14 KIY53785.1 - 5.8e-34 115.8 0.1 1.3e-33 114.6 0.0 1.6 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain Complex1_LYR_2 PF13233.6 KIY53786.1 - 1e-17 64.6 0.1 1.3e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KIY53786.1 - 1.3e-12 47.5 0.0 2.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KIY53786.1 - 0.11 13.1 0.1 0.18 12.4 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Aldo_ket_red PF00248.21 KIY53787.1 - 1.9e-53 181.6 0.0 2.4e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PHD PF00628.29 KIY53788.1 - 1e-07 31.7 11.7 2e-07 30.8 11.7 1.5 1 0 0 1 1 1 1 PHD-finger Trypan_PARP PF05887.11 KIY53788.1 - 0.00084 19.3 16.8 0.00084 19.3 16.8 3.5 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) zf-HC5HC2H PF13771.6 KIY53788.1 - 0.0037 17.5 6.4 0.0091 16.2 6.4 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain ERM PF00769.19 KIY53788.1 - 0.0068 16.3 33.9 0.0068 16.3 33.9 1.8 2 0 0 2 2 2 1 Ezrin/radixin/moesin family p450 PF00067.22 KIY53789.1 - 3.7e-09 35.8 0.0 6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 KIY53790.1 - 2.2e-58 197.8 0.0 2.7e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MARVEL PF01284.23 KIY53791.1 - 7e-09 35.9 11.9 1.1e-08 35.3 11.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.6 KIY53791.1 - 0.21 12.0 2.4 1.3 9.5 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) GPI2 PF06432.11 KIY53792.1 - 0.19 11.1 4.9 2.6 7.4 1.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Aldo_ket_red PF00248.21 KIY53793.1 - 3.8e-57 193.7 0.0 4.6e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_1 PF00561.20 KIY53794.1 - 0.14 11.8 0.1 4.7 6.8 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold TRAPP PF04051.16 KIY53795.1 - 2.3e-36 124.7 0.0 4.6e-36 123.7 0.0 1.5 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component SH3_1 PF00018.28 KIY53796.1 - 2.1e-14 52.8 0.1 3e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY53796.1 - 1.4e-11 44.0 0.1 2.1e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY53796.1 - 3.7e-11 42.5 0.0 6.2e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Aminotran_3 PF00202.21 KIY53797.1 - 6.6e-45 153.5 0.0 6.3e-44 150.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 KIY53797.1 - 1.1e-19 71.1 0.0 2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIY53797.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NmrA PF05368.13 KIY53798.1 - 8.5e-26 90.9 0.2 1.1e-25 90.5 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY53798.1 - 8.8e-20 71.4 0.0 1.3e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY53798.1 - 0.0015 18.1 0.1 0.013 15.0 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIY53798.1 - 0.0019 18.5 0.5 0.0041 17.4 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIY53798.1 - 0.0021 18.1 0.1 0.0036 17.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIY53798.1 - 0.0049 17.4 0.3 0.013 16.0 0.3 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 KIY53798.1 - 0.0076 16.2 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KIY53798.1 - 0.04 14.4 0.1 0.12 12.8 0.2 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain zf-Di19 PF05605.12 KIY53799.1 - 0.23 11.8 5.6 0.29 11.5 0.4 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 KIY53799.1 - 0.24 10.9 2.7 2.3 7.8 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 KIY53799.1 - 2.5 8.7 5.9 19 5.9 1.9 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type PI3_PI4_kinase PF00454.27 KIY53800.1 - 3.4e-20 72.9 0.0 1.2e-10 41.6 0.0 2.3 1 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KIY53800.1 - 6.2e-13 48.6 0.5 1.3e-09 37.7 0.0 3.1 1 1 1 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) NmrA PF05368.13 KIY53801.1 - 1.2e-27 97.0 0.1 1.6e-27 96.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY53801.1 - 8.8e-19 68.1 0.0 1.2e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KIY53801.1 - 0.00063 19.8 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KIY53801.1 - 0.0015 18.8 0.4 0.0043 17.3 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KIY53801.1 - 0.0031 17.5 0.1 0.0052 16.7 0.1 1.4 1 0 0 1 1 1 1 KR domain PglD_N PF17836.1 KIY53801.1 - 0.021 15.4 0.0 0.056 14.1 0.0 1.7 1 0 0 1 1 1 0 PglD N-terminal domain Epimerase PF01370.21 KIY53801.1 - 0.036 13.5 0.0 0.58 9.6 0.1 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KIY53801.1 - 0.037 14.6 1.1 0.071 13.7 0.3 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 KIY53801.1 - 0.13 12.7 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HDPD PF02924.14 KIY53801.1 - 0.27 11.3 1.9 1.4 9.0 0.4 2.2 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D YopD PF05844.12 KIY53805.1 - 0.013 14.6 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 YopD protein CxC1 PF18802.1 KIY53807.1 - 0.00019 21.6 0.0 0.00024 21.2 0.0 1.1 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIY53807.1 - 0.0058 16.8 0.0 0.0078 16.4 0.0 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY53807.1 - 0.022 14.6 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases MFS_1 PF07690.16 KIY53809.1 - 2.1e-10 40.1 15.2 2.7e-10 39.7 15.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY53809.1 - 2.4e-10 39.9 10.1 3.1e-07 29.6 8.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter SP_C-Propep PF08999.10 KIY53809.1 - 0.079 12.8 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide CDC45 PF02724.14 KIY53811.1 - 0.0061 14.9 18.0 0.01 14.2 18.0 1.3 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 KIY53811.1 - 0.026 14.0 25.5 0.064 12.7 25.5 1.6 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KIY53811.1 - 0.58 8.3 26.1 0.95 7.6 26.1 1.3 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KIY53811.1 - 6.5 6.3 29.0 0.43 10.1 22.7 2.0 2 0 0 2 2 2 0 PPP4R2 NOA36 PF06524.12 KIY53811.1 - 8.1 5.7 23.3 22 4.3 23.3 1.7 1 0 0 1 1 1 0 NOA36 protein V_ATPase_I PF01496.19 KIY53812.1 - 5.9 4.7 4.8 7.2 4.4 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KDZ PF18758.1 KIY53815.1 - 4.1e-54 183.5 0.9 1.1e-53 182.1 0.6 2.0 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY53815.1 - 6.2e-20 71.4 1.0 1.9e-19 69.8 0.1 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY53815.1 - 0.15 11.9 0.1 0.46 10.3 0.1 1.8 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases NUFIP1 PF10453.9 KIY53816.1 - 0.31 10.9 1.6 0.67 9.9 1.6 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF3574 PF12098.8 KIY53819.1 - 0.056 13.2 0.1 0.072 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Phage_integrase PF00589.22 KIY53820.1 - 0.06 13.1 0.0 0.34 10.7 0.0 1.9 1 1 0 1 1 1 0 Phage integrase family Pkinase_fungal PF17667.1 KIY53823.1 - 2.4e-05 23.3 0.0 2.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIY53823.1 - 0.0005 19.5 0.0 0.00063 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIY53823.1 - 0.028 14.3 0.1 0.059 13.3 0.1 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family XRN1_D1 PF18332.1 KIY53825.1 - 3.6e-45 154.1 0.0 6.2e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KIY53825.1 - 1.4e-31 108.5 0.1 3.5e-31 107.3 0.1 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KIY53825.1 - 1.3e-22 79.7 0.1 2.5e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KIY53825.1 - 2e-05 24.6 0.7 4.3e-05 23.5 0.3 1.7 2 0 0 2 2 2 1 Exoribonuclease 1 Domain-3 Borrelia_REV PF03978.13 KIY53825.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein MAP65_ASE1 PF03999.12 KIY53826.1 - 6.6e-61 206.8 0.0 1e-60 206.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Flagellar_rod PF05149.12 KIY53826.1 - 0.034 13.6 2.4 0.059 12.8 2.4 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein DUF3235 PF11574.8 KIY53826.1 - 0.069 14.0 0.0 0.16 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Apolipoprotein PF01442.18 KIY53826.1 - 3.2 7.6 11.9 0.037 13.9 3.9 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Hydantoinase_A PF01968.18 KIY53830.1 - 0.0066 15.7 0.3 0.0093 15.3 0.3 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Exo_endo_phos PF03372.23 KIY53830.1 - 0.051 13.1 0.1 0.072 12.6 0.1 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family M20_dimer PF07687.14 KIY53830.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.8 1 1 0 1 1 1 0 Peptidase dimerisation domain NLBH PF05211.12 KIY53833.1 - 0.03 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Phage_integrase PF00589.22 KIY53834.1 - 0.087 12.6 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Phage integrase family Pkinase_fungal PF17667.1 KIY53835.1 - 1.1e-26 93.6 0.0 8.7e-17 61.0 0.0 3.5 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 KIY53835.1 - 3.6e-08 33.6 0.8 2.5e-05 24.3 0.0 3.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY53835.1 - 0.18 11.2 0.0 0.62 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Pkinase PF00069.25 KIY53836.1 - 1e-59 202.1 0.0 2.4e-59 200.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53836.1 - 1.9e-42 145.4 0.0 3.9e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KIY53836.1 - 8.2e-39 133.5 2.6 2.4e-38 131.9 2.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.6 KIY53836.1 - 0.007 15.7 0.0 0.25 10.6 0.0 2.9 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIY53836.1 - 0.018 13.8 0.0 0.051 12.4 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KIY53836.1 - 0.027 14.4 0.0 0.027 14.4 0.0 3.0 4 0 0 4 4 4 0 Phosphotransferase enzyme family TIMELESS PF04821.14 KIY53837.1 - 6.2e-80 268.4 0.3 6.2e-80 268.4 0.3 2.5 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 KIY53837.1 - 4.6e-10 39.3 15.7 4.6e-10 39.3 15.7 2.5 2 1 0 2 2 2 1 Timeless protein C terminal region BST2 PF16716.5 KIY53838.1 - 0.011 16.3 2.3 0.014 15.9 2.3 1.4 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 JAKMIP_CC3 PF16034.5 KIY53838.1 - 0.055 13.4 3.9 0.071 13.0 3.9 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain bZIP_1 PF00170.21 KIY53838.1 - 0.098 12.8 9.1 0.61 10.2 3.1 2.2 2 1 0 2 2 2 0 bZIP transcription factor Shugoshin_N PF07558.11 KIY53838.1 - 0.15 12.0 2.3 0.29 11.1 0.8 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 KIY53838.1 - 0.26 11.4 14.5 0.64 10.1 2.4 2.3 2 1 0 2 2 2 0 Basic region leucine zipper Hydrolase_6 PF13344.6 KIY53840.1 - 4e-30 103.9 0.0 7.1e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY53840.1 - 5.4e-19 68.0 0.0 1.2e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIY53840.1 - 1.3e-12 48.5 0.0 1.7e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIY53840.1 - 1.6e-06 28.3 0.0 0.0012 18.9 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KIY53840.1 - 0.053 13.1 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase PIG-F PF06699.11 KIY53841.1 - 1.1e-30 107.1 8.2 1.7e-30 106.5 8.2 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Ribosomal_L34e PF01199.18 KIY53842.1 - 1.1e-43 147.5 3.2 1.4e-43 147.1 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 KIY53842.1 - 0.56 10.2 5.1 3.3 7.7 0.7 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain TMEM247 PF15444.6 KIY53843.1 - 0.026 14.6 0.8 0.03 14.4 0.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 DinB_2 PF12867.7 KIY53844.1 - 0.04 14.4 0.1 0.052 14.1 0.1 1.2 1 0 0 1 1 1 0 DinB superfamily FH2 PF02181.23 KIY53844.1 - 0.048 12.8 0.3 0.06 12.5 0.3 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain FapA PF03961.13 KIY53844.1 - 0.14 10.8 0.9 0.15 10.6 0.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A XhlA PF10779.9 KIY53844.1 - 0.24 11.6 0.2 0.24 11.6 0.2 2.5 2 1 0 2 2 2 0 Haemolysin XhlA Pro_isomerase PF00160.21 KIY53846.1 - 3.4e-47 160.6 0.0 5.4e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KIY53846.1 - 0.00017 21.4 0.7 0.039 14.1 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY53846.1 - 0.011 15.5 0.5 0.16 11.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5113 PF17140.4 KIY53846.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) TPR_12 PF13424.6 KIY53846.1 - 0.024 14.9 1.3 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIY53846.1 - 0.032 13.9 1.5 0.19 11.4 0.0 2.7 3 0 0 3 3 3 0 TPR repeat ELYS PF13934.6 KIY53846.1 - 0.046 13.7 0.1 0.066 13.2 0.1 1.2 1 0 0 1 1 1 0 Nuclear pore complex assembly TPR_16 PF13432.6 KIY53846.1 - 0.067 13.9 5.9 1.1 9.9 0.0 3.1 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY53846.1 - 0.39 11.4 1.5 21 6.0 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 KIY53847.1 - 1.6e-08 34.6 0.1 2.1e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY53847.1 - 0.00037 20.7 0.1 0.00048 20.3 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 KIY53847.1 - 0.046 13.8 0.8 0.11 12.6 0.8 1.8 1 1 0 1 1 1 0 TEA/ATTS domain DUF1770 PF08589.10 KIY53848.1 - 0.31 12.0 0.0 0.31 12.0 0.0 3.0 3 1 0 3 3 3 0 Fungal protein of unknown function (DUF1770) Pkinase_fungal PF17667.1 KIY53849.1 - 7.9e-31 107.2 0.0 5.1e-20 71.6 0.0 3.9 2 1 1 3 3 3 3 Fungal protein kinase APH PF01636.23 KIY53849.1 - 2.9e-09 37.2 0.1 4.5e-06 26.7 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 KIY53849.1 - 0.07 12.5 0.0 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain PAP1 PF08601.10 KIY53849.1 - 3.1 7.4 19.9 5.9 6.5 7.8 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 SNO PF01174.19 KIY53850.1 - 2.8e-50 170.8 0.0 4.4e-40 137.5 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KIY53850.1 - 4.8e-07 29.6 0.0 6.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KIY53850.1 - 1.9e-05 24.4 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 KIY53850.1 - 0.093 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Prp19 PF08606.11 KIY53851.1 - 0.0054 16.7 2.2 1.2 9.2 0.1 2.6 2 0 0 2 2 2 2 Prp19/Pso4-like APG6_N PF17675.1 KIY53851.1 - 0.011 16.3 5.0 0.023 15.2 5.0 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region GAS PF13851.6 KIY53851.1 - 0.024 14.0 1.7 0.04 13.3 1.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KIY53851.1 - 0.03 13.4 0.9 0.056 12.5 0.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KIY53851.1 - 0.031 14.7 0.6 0.067 13.6 0.6 1.6 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 KIY53851.1 - 0.043 12.7 2.2 0.065 12.1 2.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin PF00804.25 KIY53851.1 - 0.072 12.7 1.9 0.19 11.4 0.5 2.2 2 0 0 2 2 2 0 Syntaxin TMF_TATA_bd PF12325.8 KIY53851.1 - 0.073 13.3 1.4 11 6.2 0.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding KASH_CCD PF14662.6 KIY53851.1 - 0.17 11.7 1.1 0.29 11.0 1.1 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 KIY53851.1 - 0.2 11.4 3.0 0.26 11.1 0.7 2.1 2 0 0 2 2 2 0 Septum formation initiator TolA_bind_tri PF16331.5 KIY53851.1 - 0.32 11.1 4.1 0.76 9.9 0.5 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF4407 PF14362.6 KIY53851.1 - 0.74 9.1 4.9 1.7 7.9 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 KIY53851.1 - 1.5 9.1 4.4 21 5.4 3.3 2.7 2 1 0 2 2 1 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 KIY53851.1 - 1.6 8.8 4.2 6.1 6.9 4.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1320 PF07030.12 KIY53852.1 - 0.039 14.1 0.2 0.063 13.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1320) Ribosomal_L31e PF01198.19 KIY53854.1 - 2.7e-39 133.3 1.6 3.3e-39 133.0 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Pkinase_fungal PF17667.1 KIY53855.1 - 2.1e-26 92.7 0.0 6.8e-16 58.0 0.0 3.7 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 KIY53855.1 - 1.2e-08 35.2 0.1 5.3e-05 23.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KIY53855.1 - 0.0057 16.1 0.0 0.046 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DUF5432 PF17497.2 KIY53856.1 - 0.094 12.8 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5432) DUF1770 PF08589.10 KIY53856.1 - 0.15 13.1 1.4 0.29 12.1 0.1 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) CFEM PF05730.11 KIY53858.1 - 5.6e-11 42.4 11.4 6.9e-11 42.1 11.4 1.1 1 0 0 1 1 1 1 CFEM domain Glug PF07581.12 KIY53858.1 - 0.14 12.6 1.7 9.2 6.9 0.1 2.5 2 0 0 2 2 2 0 The GLUG motif PTCB-BRCT PF12738.7 KIY53859.1 - 2.2e-25 88.3 0.2 2.8e-09 36.8 0.0 4.9 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.26 KIY53859.1 - 3e-18 66.0 0.0 6.6e-07 29.6 0.0 3.9 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KIY53859.1 - 0.00078 19.8 0.0 0.042 14.2 0.0 2.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KIY53859.1 - 0.0031 17.8 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain FSA_C PF10479.9 KIY53860.1 - 1.6 6.8 5.8 2.6 6.1 5.8 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pribosyltran PF00156.27 KIY53861.1 - 3.4e-16 59.2 0.1 5e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AA_permease_2 PF13520.6 KIY53862.1 - 1.3e-41 142.9 54.6 1.6e-41 142.6 54.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY53862.1 - 2.6e-22 79.1 44.4 3.1e-22 78.8 44.4 1.1 1 0 0 1 1 1 1 Amino acid permease RNA_Me_trans PF04252.13 KIY53863.1 - 2.8e-71 239.2 0.0 3.5e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase RNA_Me_trans PF04252.13 KIY53864.1 - 1.6e-74 249.8 0.0 2e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Sugar_tr PF00083.24 KIY53867.1 - 7e-110 368.0 25.6 8.1e-110 367.8 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY53867.1 - 2.8e-28 98.8 22.7 2.8e-28 98.8 22.7 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY53867.1 - 2.4e-05 23.0 3.8 2.4e-05 23.0 3.8 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KIY53867.1 - 0.00033 19.1 1.6 0.00059 18.3 0.7 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Proteasom_PSMB PF10508.9 KIY53867.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Methyltransf_2 PF00891.18 KIY53868.1 - 3e-25 88.7 0.0 1.4e-23 83.3 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 KIY53868.1 - 0.094 13.4 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIY53868.1 - 0.18 11.3 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain ABC_tran PF00005.27 KIY53870.1 - 5.8e-48 162.9 0.0 2e-28 99.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY53870.1 - 2.2e-42 145.6 26.4 9.7e-26 91.0 7.4 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY53870.1 - 7.4e-08 32.1 0.0 0.011 15.2 0.6 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KIY53870.1 - 7e-05 22.5 0.0 0.039 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY53870.1 - 0.00086 19.0 0.5 0.28 11.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIY53870.1 - 0.0018 18.8 0.1 1.6 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KIY53870.1 - 0.004 17.4 0.4 5.9 7.2 0.1 3.2 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIY53870.1 - 0.037 13.9 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 KIY53870.1 - 0.042 13.2 0.2 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF87 PF01935.17 KIY53870.1 - 0.046 13.8 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain NB-ARC PF00931.22 KIY53870.1 - 0.054 12.7 0.0 3.3 6.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_16 PF13191.6 KIY53870.1 - 0.094 13.1 0.0 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KIY53870.1 - 0.15 11.7 0.1 0.8 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.19 KIY53870.1 - 0.44 11.2 9.0 2.9 8.5 0.1 3.1 3 0 0 3 3 2 0 60s Acidic ribosomal protein Evr1_Alr PF04777.13 KIY53872.1 - 1.7e-28 99.0 0.3 2.1e-28 98.7 0.3 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Shadoo PF14999.6 KIY53872.1 - 0.0025 17.9 0.8 0.0032 17.6 0.8 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Cation_efflux PF01545.21 KIY53873.1 - 0.055 13.2 4.6 0.12 12.1 4.6 1.5 1 1 0 1 1 1 0 Cation efflux family HNH_2 PF13391.6 KIY53874.1 - 5.7e-08 32.8 0.1 1.4e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease Ofd1_CTDD PF10637.9 KIY53876.1 - 1.1e-75 254.3 0.0 1.9e-73 247.0 0.0 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KIY53876.1 - 5.8e-27 94.2 0.0 2.9e-26 92.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KIY53876.1 - 7.9e-13 49.1 0.0 2.3e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HTH_31 PF13560.6 KIY53877.1 - 0.018 15.4 0.0 0.19 12.1 0.0 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 KIY53877.1 - 0.097 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Nop53 PF07767.11 KIY53878.1 - 0.0022 17.4 1.6 0.0036 16.8 1.6 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FTP PF07504.13 KIY53878.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif NAD_binding_10 PF13460.6 KIY53879.1 - 0.008 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RNA_Me_trans PF04252.13 KIY53881.1 - 5.2e-71 238.4 0.0 6.2e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase AA_permease_2 PF13520.6 KIY53882.1 - 6.7e-43 147.1 53.3 8.6e-43 146.7 53.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY53882.1 - 2.5e-23 82.4 42.2 3.3e-23 82.0 42.2 1.1 1 0 0 1 1 1 1 Amino acid permease PGM_PMM_III PF02880.16 KIY53882.1 - 0.12 12.5 0.1 0.46 10.7 0.2 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Pribosyltran PF00156.27 KIY53883.1 - 4.5e-16 58.8 0.1 6.4e-16 58.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.25 KIY53884.1 - 3.3e-12 46.3 0.0 3.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53884.1 - 0.00042 19.7 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY53887.1 - 2.5e-13 50.5 0.3 3.9e-13 49.9 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY53887.1 - 0.0016 17.9 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 KIY53887.1 - 0.0035 16.9 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIY53887.1 - 0.05 13.2 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIY53888.1 - 4.6e-15 56.2 0.1 7.3e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY53888.1 - 0.0018 17.7 0.0 0.65 9.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 KIY53888.1 - 0.0096 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIY53888.1 - 0.039 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family TetR_C_34 PF17929.1 KIY53888.1 - 0.11 12.7 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Fungal_trans PF04082.18 KIY53890.1 - 4.2e-21 75.2 0.0 7.7e-21 74.3 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain PI-PLC-X PF00388.19 KIY53891.1 - 4.9e-56 188.3 0.1 8.9e-56 187.5 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIY53891.1 - 5.4e-41 139.5 0.0 1.2e-40 138.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.6 KIY53891.1 - 5.2e-07 30.0 0.3 1.1e-05 25.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair C2 PF00168.30 KIY53891.1 - 7.2e-07 29.4 0.0 1.1e-05 25.6 0.0 2.4 1 1 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 KIY53891.1 - 5.1e-05 23.7 0.2 0.00014 22.3 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_14 PF17787.1 KIY53891.1 - 0.0028 17.5 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 KIY53891.1 - 0.0055 16.5 0.6 18 5.6 0.1 4.0 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KIY53891.1 - 0.012 15.1 0.2 36 4.2 0.0 3.8 3 0 0 3 3 3 0 EF hand PH_12 PF16457.5 KIY53891.1 - 0.11 13.0 0.0 0.38 11.3 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain NLE PF08154.12 KIY53892.1 - 5.1e-15 55.7 0.0 9.5e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KIY53892.1 - 4e-14 52.8 18.3 0.078 13.9 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.6 KIY53892.1 - 0.00019 21.8 3.6 0.34 11.4 0.0 4.5 5 0 0 5 5 5 2 PQQ-like domain PQQ PF01011.21 KIY53892.1 - 0.18 11.8 0.7 0.62 10.1 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat Nup160 PF11715.8 KIY53892.1 - 0.63 8.6 3.9 8 5.0 0.1 2.9 1 1 1 3 3 3 0 Nucleoporin Nup120/160 AMP-binding PF00501.28 KIY53893.1 - 2.2e-90 303.3 0.1 2.7e-90 303.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY53893.1 - 2.8e-25 89.1 0.2 1e-24 87.3 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KIY53893.1 - 1.8e-12 47.0 0.2 6.2e-11 42.1 0.2 2.9 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 KIY53893.1 - 0.05 13.5 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) EKR PF10371.9 KIY53893.1 - 0.082 12.7 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function ABC_tran PF00005.27 KIY53894.1 - 1.1e-48 165.2 0.0 4.6e-29 101.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY53894.1 - 5.3e-45 154.2 12.5 9.8e-25 87.7 1.7 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KIY53894.1 - 1.1e-07 31.5 0.0 0.016 14.7 0.0 3.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KIY53894.1 - 8.4e-05 22.2 0.0 0.11 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY53894.1 - 0.0019 17.9 1.1 0.41 10.4 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY53894.1 - 0.0067 16.7 0.2 10 6.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIY53894.1 - 0.0081 16.7 0.4 4.1 7.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KIY53894.1 - 0.033 13.5 0.5 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 KIY53894.1 - 0.034 13.9 0.1 12 5.6 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 KIY53894.1 - 0.045 13.8 0.2 0.093 12.8 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain NB-ARC PF00931.22 KIY53894.1 - 0.067 12.4 0.1 4.5 6.4 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_16 PF13191.6 KIY53894.1 - 0.15 12.5 0.1 2.5 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Molybdopterin PF00384.22 KIY53895.1 - 2e-69 234.6 0.0 4.9e-67 226.8 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KIY53895.1 - 4.3e-20 71.5 0.4 1.6e-19 69.7 0.4 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KIY53895.1 - 9.4e-18 63.5 0.2 9.4e-18 63.5 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KIY53895.1 - 9.6e-16 58.2 0.0 2.1e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KIY53895.1 - 2.4e-08 33.8 2.9 2.4e-08 33.8 0.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KIY53895.1 - 0.00036 20.3 0.5 0.0078 16.0 0.2 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KIY53895.1 - 0.089 12.7 1.1 4.6 7.2 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Aldo_ket_red PF00248.21 KIY53896.1 - 1.4e-34 119.6 0.0 3.9e-33 114.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Metallophos PF00149.28 KIY53897.1 - 4.5e-07 30.6 0.1 8.1e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NB-ARC PF00931.22 KIY53898.1 - 1.3e-05 24.5 0.0 4e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KIY53898.1 - 3.5e-05 24.1 0.0 8.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KIY53898.1 - 5.2e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIY53898.1 - 7.7e-05 23.1 3.2 0.02 15.3 3.2 2.6 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIY53898.1 - 0.021 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIY53898.1 - 0.03 14.7 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KIY53898.1 - 0.035 14.2 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIY53898.1 - 0.2 11.4 0.3 0.54 10.0 0.0 1.8 2 1 0 2 2 2 0 IstB-like ATP binding protein DUF2461 PF09365.10 KIY53899.1 - 2e-67 227.2 0.0 2.6e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) PPV_E1_C PF00519.17 KIY53899.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase G_glu_transpept PF01019.21 KIY53901.1 - 8e-148 493.4 0.0 9.3e-148 493.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Aldo_ket_red PF00248.21 KIY53902.1 - 4.6e-36 124.5 0.0 3.1e-34 118.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Metallophos PF00149.28 KIY53903.1 - 1.7e-09 38.5 0.1 2.8e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY53903.1 - 3.5e-05 24.1 0.0 0.00031 21.0 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Zn_clus PF00172.18 KIY53905.1 - 1.1e-05 25.5 9.5 1.9e-05 24.7 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.16 KIY53908.1 - 1.7e-38 132.4 0.0 3.3e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KIY53908.1 - 3.1e-17 63.1 0.0 4.7e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KIY53908.1 - 1.8e-15 57.4 0.3 4.3e-15 56.2 0.3 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KIY53908.1 - 6e-11 41.8 0.0 1.3e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 KIY53908.1 - 0.0016 19.1 0.0 0.046 14.4 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-MYND PF01753.18 KIY53909.1 - 2.1e-06 27.7 10.4 5.5e-06 26.4 10.4 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY53909.1 - 0.16 12.3 9.3 0.4 11.0 9.3 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Carb_bind PF10645.9 KIY53909.1 - 0.49 10.7 4.2 1.5 9.1 4.2 1.8 1 0 0 1 1 1 0 Carbohydrate binding Tannase PF07519.11 KIY53910.1 - 8.5e-104 348.0 0.8 1.1e-103 347.6 0.8 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase ApbA PF02558.16 KIY53911.1 - 3.7e-30 104.6 0.0 5e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KIY53911.1 - 1.6e-29 102.6 0.1 4.3e-29 101.2 0.1 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal N2227 PF07942.12 KIY53912.1 - 3.3e-96 321.6 0.0 4.3e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KIY53912.1 - 0.0014 19.3 0.0 0.0095 16.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY53912.1 - 0.0058 16.5 0.0 0.026 14.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY53912.1 - 0.021 15.4 0.0 1.9 9.2 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain UbiA PF01040.18 KIY53913.1 - 5.3e-39 134.0 21.4 8.5e-39 133.4 21.4 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Nop53 PF07767.11 KIY53914.1 - 6.2e-89 299.2 5.2 7.1e-89 299.0 5.2 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BOP1NT PF08145.12 KIY53914.1 - 0.00025 21.0 1.2 0.0061 16.5 0.2 2.3 2 0 0 2 2 2 2 BOP1NT (NUC169) domain zf-RVT PF13966.6 KIY53915.1 - 1.9e-06 28.5 0.4 3.7e-06 27.6 0.4 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase UCH_C PF18031.1 KIY53916.1 - 0.15 11.9 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Chitin_synth_2 PF03142.15 KIY53918.1 - 1.3e-237 789.6 1.0 1.8e-237 789.1 1.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KIY53918.1 - 3.3e-119 399.1 0.0 9.2e-119 397.6 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KIY53918.1 - 1.9e-20 72.5 0.0 5.5e-20 71.0 0.1 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KIY53918.1 - 1.2e-10 41.7 3.1 1.2e-10 41.7 3.1 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KIY53918.1 - 6.7e-10 39.0 1.6 0.00042 20.4 0.2 3.3 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KIY53918.1 - 1.4e-09 38.2 0.1 9e-08 32.3 0.1 2.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIY53918.1 - 7.4e-06 25.9 0.0 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_16 PF13191.6 KIY53918.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain F-box PF00646.33 KIY53919.1 - 0.011 15.7 0.5 0.042 13.7 0.5 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIY53919.1 - 0.055 13.4 0.3 0.14 12.1 0.3 1.7 1 0 0 1 1 1 0 F-box-like AAA_12 PF13087.6 KIY53920.1 - 1.5e-38 132.4 0.1 2.9e-38 131.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY53920.1 - 1.6e-14 54.4 0.0 4.7e-11 43.0 0.0 3.2 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 KIY53920.1 - 2.8e-07 30.9 1.1 3.1e-06 27.6 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIY53920.1 - 0.00011 22.0 0.0 0.0007 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIY53920.1 - 0.00055 19.3 0.0 0.17 11.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KIY53920.1 - 0.034 13.9 0.0 3.4 7.3 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase zf-CCCH PF00642.24 KIY53920.1 - 0.035 14.0 4.2 0.11 12.4 4.2 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY53920.1 - 0.056 14.1 0.1 0.66 10.7 0.1 2.5 2 0 0 2 2 2 0 Torus domain T2SSE PF00437.20 KIY53920.1 - 0.091 11.8 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-CCCH_4 PF18044.1 KIY53920.1 - 0.19 11.5 1.4 0.55 10.1 1.4 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger ApbA PF02558.16 KIY53922.1 - 3.3e-27 95.0 0.0 3.9e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Tannase PF07519.11 KIY53923.1 - 6e-104 348.6 0.4 7.4e-104 348.3 0.4 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase ABC2_membrane PF01061.24 KIY53924.1 - 7.5e-09 35.3 7.7 1e-08 34.9 7.7 1.1 1 0 0 1 1 1 1 ABC-2 type transporter zf-MYND PF01753.18 KIY53926.1 - 1.1e-05 25.4 11.8 2.4e-05 24.3 11.8 1.7 1 1 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY53926.1 - 0.0087 16.3 6.6 0.0087 16.3 6.6 1.9 2 1 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Anophelin PF10731.9 KIY53930.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Sod_Fe_C PF02777.18 KIY53931.1 - 4e-33 113.6 0.0 7e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIY53931.1 - 2.4e-31 108.0 3.6 4.4e-31 107.2 2.4 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pkinase_fungal PF17667.1 KIY53932.1 - 0.00011 21.1 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIY53932.1 - 0.00061 19.2 0.0 0.00072 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIY53932.1 - 0.054 13.4 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family NPR2 PF06218.11 KIY53935.1 - 3.5e-88 296.3 4.5 2.8e-68 230.7 5.8 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Fungal_trans PF04082.18 KIY53936.1 - 2.5e-30 105.4 0.7 3.7e-30 104.9 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 KIY53936.1 - 0.0013 18.8 0.1 0.0025 17.9 0.1 1.4 1 0 0 1 1 1 1 Gal4-like dimerisation domain DUF5063 PF16702.5 KIY53936.1 - 0.11 12.9 0.0 0.68 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) DUF1746 PF08508.10 KIY53938.1 - 0.12 12.8 0.2 0.25 11.7 0.1 1.6 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Ribosomal_S8e PF01201.22 KIY53939.1 - 3.9e-47 159.9 0.3 3.9e-47 159.9 0.3 2.1 1 1 1 2 2 2 2 Ribosomal protein S8e Oxidored_FMN PF00724.20 KIY53940.1 - 6.6e-89 298.5 0.0 7.5e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PGM_PMM_II PF02879.16 KIY53940.1 - 0.16 12.6 0.0 0.61 10.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Fer2_BFD PF04324.15 KIY53941.1 - 0.05 14.0 0.1 0.62 10.5 0.0 2.4 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Vps8 PF12816.7 KIY53943.1 - 4.5e-71 238.5 0.0 7.5e-68 227.9 0.0 2.4 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KIY53943.1 - 3.6e-08 33.4 0.0 0.00053 19.9 0.2 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Rrn6 PF10214.9 KIY53943.1 - 0.028 12.9 0.1 0.53 8.7 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor WD40 PF00400.32 KIY53943.1 - 0.097 13.6 0.0 3.9 8.5 0.0 3.5 2 0 0 2 2 2 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY53943.1 - 0.18 12.1 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1168 PF06658.12 KIY53944.1 - 6e-39 133.0 12.7 9.1e-39 132.4 12.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) CENP-Q PF13094.6 KIY53944.1 - 0.0073 16.5 5.8 0.0073 16.5 5.8 1.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Lyase_catalyt PF09093.11 KIY53944.1 - 0.085 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic DUF4692 PF15763.5 KIY53944.1 - 0.094 13.2 2.0 0.19 12.2 2.0 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) tRNA_synt_1c_R2 PF04557.15 KIY53944.1 - 0.64 11.0 11.4 4 8.4 11.4 2.2 1 1 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Retrotran_gag_2 PF14223.6 KIY53945.1 - 0.0027 17.4 0.4 0.004 16.8 0.4 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RRM_2 PF04059.12 KIY53946.1 - 1.5e-31 108.5 1.5 1.8e-31 108.2 1.5 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KIY53946.1 - 4.6e-05 23.2 0.1 7.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KIY53946.1 - 0.0086 16.3 0.1 0.012 15.9 0.1 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 Smg4_UPF3 PF03467.15 KIY53946.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Peptidase_S41 PF03572.18 KIY53947.1 - 3.8e-05 23.3 0.0 9.2e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 PhoLip_ATPase_C PF16212.5 KIY53948.1 - 5.3e-80 268.8 26.3 5.3e-80 268.8 26.3 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIY53948.1 - 6.3e-25 86.7 4.5 2.3e-24 84.9 4.5 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KIY53948.1 - 6.1e-12 45.5 0.0 1.9e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIY53948.1 - 4.6e-10 40.2 2.2 9.5e-06 26.0 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIY53948.1 - 1.7e-08 34.2 0.0 4.7e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIY53948.1 - 0.0069 16.2 0.1 0.026 14.3 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tmpp129 PF10272.9 KIY53948.1 - 0.49 9.6 2.5 9.1 5.5 0.8 2.5 1 1 1 2 2 2 0 Putative transmembrane protein precursor Ribosomal_S6 PF01250.17 KIY53949.1 - 2.3e-18 66.2 0.0 2.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Hydrolase PF00702.26 KIY53950.1 - 8.1e-15 55.7 0.0 1e-14 55.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIY53950.1 - 1.7e-11 44.5 0.0 2e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY53950.1 - 3.8e-07 30.1 0.0 7.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PI-PLC-X PF00388.19 KIY53950.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.5 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Amidohydro_2 PF04909.14 KIY53951.1 - 7.6e-07 29.2 0.0 9.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Aldo_ket_red PF00248.21 KIY53952.1 - 3.4e-65 220.2 0.0 4.4e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CBF PF03914.17 KIY53953.1 - 1.9e-30 106.1 1.4 1.9e-30 106.1 1.4 3.1 4 0 0 4 4 4 1 CBF/Mak21 family MOR2-PAG1_C PF14225.6 KIY53953.1 - 0.0061 16.4 0.1 0.021 14.7 0.1 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal O-FucT PF10250.9 KIY53954.1 - 2.8e-06 27.3 0.0 5.7e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF5010 PF16402.5 KIY53954.1 - 0.085 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) GST_N_3 PF13417.6 KIY53955.1 - 1.5e-16 60.6 0.0 4.7e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY53955.1 - 4.5e-13 49.2 0.0 6.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIY53955.1 - 8.2e-12 45.3 0.0 1.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY53955.1 - 1.2e-07 32.0 0.0 3.2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY53955.1 - 1.5e-05 25.1 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY53955.1 - 1.7e-05 24.8 0.0 4.2e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3613 PF12266.8 KIY53955.1 - 0.18 11.6 1.4 0.4 10.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) Glyco_transf_49 PF13896.6 KIY53956.1 - 0.036 13.4 0.1 0.099 12.0 0.1 1.7 1 1 1 2 2 2 0 Glycosyl-transferase for dystroglycan RhoGAP PF00620.27 KIY53956.1 - 0.063 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 RhoGAP domain DUF775 PF05603.12 KIY53957.1 - 0.44 10.1 4.4 0.92 9.0 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) FAM76 PF16046.5 KIY53957.1 - 3 7.1 8.9 5 6.4 8.9 1.2 1 0 0 1 1 1 0 FAM76 protein DNA_pol_B PF00136.21 KIY53958.1 - 1.1e-12 47.5 0.0 1.4e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B p450 PF00067.22 KIY53959.1 - 2.3e-48 165.1 0.0 4.9e-48 164.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 LRR_12 PF18837.1 KIY53959.1 - 0.12 12.0 0.2 2.6 7.7 0.1 2.5 2 0 0 2 2 2 0 Leucine-rich repeat Pkinase PF00069.25 KIY53960.1 - 1.4e-66 224.6 0.0 1.8e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53960.1 - 8.9e-29 100.5 0.0 1.2e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY53960.1 - 0.016 14.2 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain WD40 PF00400.32 KIY53960.1 - 0.017 16.0 0.0 0.04 14.8 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat APH PF01636.23 KIY53960.1 - 0.045 13.7 0.2 0.17 11.8 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY53960.1 - 0.079 12.3 0.1 0.15 11.4 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Use1 PF09753.9 KIY53961.1 - 7.8e-17 61.8 9.6 8.1e-16 58.5 9.6 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 Mfa2 PF08842.10 KIY53961.1 - 0.037 13.6 0.1 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 DUF5383 PF17355.2 KIY53961.1 - 0.068 13.6 4.3 0.062 13.7 1.2 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5383) FUSC-like PF12805.7 KIY53961.1 - 0.071 12.2 1.7 0.082 12.0 0.3 1.8 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS RIFIN PF02009.16 KIY53961.1 - 0.11 12.4 3.1 0.083 12.8 0.9 1.7 2 0 0 2 2 2 0 Rifin Sec20 PF03908.13 KIY53961.1 - 0.15 12.0 4.4 0.41 10.6 2.6 2.3 2 0 0 2 2 2 0 Sec20 T2SSF PF00482.23 KIY53961.1 - 0.26 11.3 1.2 1.2 9.1 1.2 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Exonuc_VII_L PF02601.15 KIY53961.1 - 1.6 8.2 6.8 0.45 10.0 1.7 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Yae1_N PF09811.9 KIY53964.1 - 0.00024 20.7 10.6 0.0058 16.3 2.4 2.5 1 1 1 2 2 2 2 Essential protein Yae1, N terminal Cnn_1N PF07989.11 KIY53964.1 - 0.19 11.9 2.2 0.7 10.1 2.2 2.0 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Pkinase PF00069.25 KIY53965.1 - 1.6e-44 152.3 0.0 1.9e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53965.1 - 2.4e-23 82.8 0.0 1.9e-22 79.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY53965.1 - 2e-06 27.9 0.1 7.7e-06 26.0 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY53965.1 - 5.4e-06 25.4 0.0 7.8e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIY53965.1 - 0.00028 20.5 0.0 0.00038 20.1 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KIY53965.1 - 0.0021 17.4 0.0 1.1 8.5 0.0 2.2 2 1 0 2 2 2 2 Kinase-like DUF1679 PF07914.11 KIY53965.1 - 0.055 12.3 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.14 KIY53965.1 - 0.065 12.6 0.1 0.093 12.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G PF02854.19 KIY53966.1 - 5.1e-45 153.7 3.2 1.1e-29 103.7 0.2 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KIY53966.1 - 5.9e-29 101.5 7.0 5.9e-29 101.5 7.0 3.3 3 0 0 3 3 3 1 Up-frameshift suppressor 2 E1-E2_ATPase PF00122.20 KIY53967.1 - 4e-30 104.7 1.7 4.6e-30 104.5 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 KIY53967.1 - 3.8e-21 75.5 0.1 8.2e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KIY53967.1 - 5.8e-18 65.9 0.3 1.6e-06 28.6 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KIY53967.1 - 7.8e-08 32.2 6.1 2e-07 30.9 6.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KIY53967.1 - 7.5e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIY53967.1 - 1.9e-05 24.3 0.0 4.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Sulfatase PF00884.23 KIY53968.1 - 9.6e-78 261.7 0.0 1.2e-77 261.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 KIY53968.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Sulfatase_C PF14707.6 KIY53968.1 - 0.013 16.3 0.1 0.16 12.7 0.1 2.3 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF229 PF02995.17 KIY53968.1 - 0.048 12.3 0.0 0.068 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4976 PF16347.5 KIY53968.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Lactamase_B PF00753.27 KIY53969.1 - 1.3e-05 25.3 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIY53969.1 - 0.00034 20.2 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain V-SNARE_C PF12352.8 KIY53970.1 - 1.1e-14 54.5 0.6 2.5e-14 53.3 0.2 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KIY53970.1 - 1.5e-06 28.0 0.3 5.5e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Sec20 FAM72 PF14976.6 KIY53971.1 - 4.8e-17 62.5 4.5 1e-16 61.4 4.5 1.4 1 0 0 1 1 1 1 FAM72 protein Nop25 PF09805.9 KIY53972.1 - 4.3e-19 69.3 10.0 4.3e-19 69.3 10.0 2.8 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) RibD_C PF01872.17 KIY53972.1 - 0.35 10.7 2.5 0.45 10.3 0.5 1.9 1 1 1 2 2 2 0 RibD C-terminal domain Glyco_hydro_18 PF00704.28 KIY53973.1 - 1.3e-21 77.7 1.8 1.5e-21 77.4 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.23 KIY53974.1 - 1.7e-136 444.1 18.7 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KIY53974.1 - 1.5e-63 210.6 20.3 1.9e-15 56.5 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIY53974.1 - 4.6e-23 81.5 9.0 0.00045 20.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KIY53974.1 - 2.9e-16 59.2 2.8 0.029 14.3 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY53974.1 - 1.7e-14 53.8 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIY53974.1 - 4e-14 52.8 7.6 0.044 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 KIY53974.1 - 4.1e-13 49.8 1.0 0.35 11.4 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KIY53974.1 - 5.6e-10 39.3 0.4 1.1 9.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KIY53974.1 - 3.6e-07 30.1 24.2 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KIY53974.1 - 4.7e-07 29.4 0.5 0.97 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF2870 PF11069.8 KIY53974.1 - 3.1e-06 27.5 0.0 17 5.9 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 KIY53974.1 - 3.9e-06 26.9 2.8 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 KIY53974.1 - 4.3e-06 27.4 0.1 28 5.6 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain ACT_5 PF13710.6 KIY53974.1 - 1e-05 25.3 3.8 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 KIY53974.1 - 1.3e-05 25.2 0.1 29 4.9 0.0 4.7 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 KIY53974.1 - 5.9e-05 23.1 3.2 6.9 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KIY53974.1 - 0.00033 20.1 0.1 21 4.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KIY53974.1 - 0.00036 21.0 0.9 73 4.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.14 KIY53974.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KIY53974.1 - 0.0093 16.1 0.0 91 3.3 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KIY53974.1 - 0.011 15.9 5.3 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KIY53974.1 - 0.041 13.7 9.2 43 4.1 0.1 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 KIY53974.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 KIY53974.1 - 0.41 11.1 9.3 3.8e+03 -1.6 9.3 4.0 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KIY53974.1 - 1.1 9.5 4.6 2.4e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KIY53974.1 - 1.2 9.0 8.5 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KIY53974.1 - 1.2 9.3 9.9 1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein Prefoldin PF02996.17 KIY53975.1 - 4.7e-27 94.3 0.8 5.9e-27 94.0 0.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KIY53975.1 - 0.0065 16.4 2.8 0.24 11.4 0.2 2.3 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 KIY53975.1 - 0.0096 16.0 0.1 0.02 15.0 0.1 1.6 1 1 0 1 1 1 1 Prefoldin subunit EAP30 PF04157.16 KIY53975.1 - 0.0098 15.2 2.2 0.22 10.8 0.1 2.1 2 0 0 2 2 2 1 EAP30/Vps36 family Baculo_PEP_C PF04513.12 KIY53975.1 - 0.011 15.7 3.1 1.9 8.5 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med30 PF11315.8 KIY53975.1 - 0.012 15.8 1.7 0.21 11.8 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 AIP3 PF03915.13 KIY53975.1 - 0.019 14.1 2.5 0.024 13.7 2.5 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF1664 PF07889.12 KIY53975.1 - 0.019 15.0 3.7 0.75 9.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KIY53975.1 - 0.021 14.9 1.5 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ANAPC_CDC26 PF10471.9 KIY53975.1 - 0.04 14.7 2.0 0.04 14.7 2.0 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 SPATA24 PF15175.6 KIY53975.1 - 0.079 12.9 0.8 0.079 12.9 0.8 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 FlaC_arch PF05377.11 KIY53975.1 - 0.081 13.3 1.1 3.4 8.1 0.0 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_MT_bd PF06657.13 KIY53975.1 - 0.1 13.0 2.3 0.39 11.2 0.2 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 RasGAP_C PF03836.15 KIY53975.1 - 0.11 12.6 4.5 2.7 8.2 0.4 2.1 2 0 0 2 2 2 0 RasGAP C-terminus HIP1_clath_bdg PF16515.5 KIY53975.1 - 0.2 12.3 6.7 1.1 10.0 0.7 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 KIY53975.1 - 0.2 12.0 6.4 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF883 PF05957.13 KIY53975.1 - 0.25 12.0 1.3 2.9 8.6 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) UPF0449 PF15136.6 KIY53975.1 - 0.29 11.6 5.2 6.5 7.3 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 GIT_CC PF16559.5 KIY53975.1 - 0.42 10.5 10.3 4.7 7.1 4.9 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor WXG100 PF06013.12 KIY53975.1 - 2.4 8.4 6.6 14 6.0 0.4 2.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG bZIP_2 PF07716.15 KIY53975.1 - 4.1 7.6 6.1 2.2 8.4 1.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper YlqD PF11068.8 KIY53975.1 - 5.2 7.4 8.9 1.2 9.5 1.3 2.1 2 0 0 2 2 2 0 YlqD protein ABM PF03992.16 KIY53976.1 - 1.5e-07 31.5 0.8 0.0003 20.8 0.0 2.8 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 KIY53976.1 - 0.01 16.1 0.4 1.8 8.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) Abhydro_lipase PF04083.16 KIY53978.1 - 1.8e-21 75.5 0.0 3e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KIY53978.1 - 1.1e-20 74.4 0.2 2.2e-20 73.4 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KIY53978.1 - 0.00013 21.7 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KIY53978.1 - 0.0014 18.0 0.0 1.1 8.5 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Alpha-amylase PF00128.24 KIY53979.1 - 9.5e-120 400.2 0.1 1.5e-119 399.5 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KIY53979.1 - 2.6e-07 30.7 0.0 5.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KIY53979.1 - 0.00016 20.9 0.0 0.00027 20.2 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 KIY53979.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) G-patch PF01585.23 KIY53980.1 - 5.6e-06 26.2 0.1 8.1e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KIY53980.1 - 0.039 14.0 0.7 0.094 12.8 0.1 1.8 2 0 0 2 2 2 0 G-patch domain MTS PF05175.14 KIY53981.1 - 4.5e-09 36.1 0.0 3.5e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIY53981.1 - 0.0023 18.6 0.0 0.0043 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY53981.1 - 0.0035 17.1 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KIY53981.1 - 0.0075 15.7 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 KIY53981.1 - 0.026 14.2 0.0 0.065 12.9 0.0 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit rRNA_methylase PF06962.12 KIY53981.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative rRNA methylase Cys_Met_Meta_PP PF01053.20 KIY53981.1 - 0.11 11.0 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Methyltransf_12 PF08242.12 KIY53981.1 - 0.11 13.3 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KIY53981.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 KIY53981.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_31 PF13847.6 KIY53981.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0029 PF01205.19 KIY53982.1 - 2.4e-25 88.9 0.0 2.9e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 GFA PF04828.14 KIY53983.1 - 0.0002 21.7 0.8 0.00075 19.8 0.0 2.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_15 PF00723.21 KIY53984.1 - 2.1e-89 300.4 0.9 2.5e-89 300.1 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KIY53984.1 - 2.3e-29 101.1 0.4 5.1e-29 100.0 0.4 1.6 1 0 0 1 1 1 1 Starch binding domain VID27 PF08553.10 KIY53986.1 - 0.2 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Josephin PF02099.17 KIY53987.1 - 3.9e-37 127.9 7.0 6e-33 114.3 0.0 2.6 2 1 1 3 3 3 2 Josephin DUF2407_C PF13373.6 KIY53990.1 - 5.8e-22 78.4 8.7 5.2e-20 72.1 8.7 2.9 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KIY53990.1 - 1.6e-17 64.0 0.0 2.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KIY53990.1 - 1.6e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family AI-2E_transport PF01594.16 KIY53990.1 - 0.048 12.8 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 AI-2E family transporter Abhydrolase_1 PF00561.20 KIY53991.1 - 3.4e-21 76.0 0.0 1.3e-20 74.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY53991.1 - 5.2e-18 65.2 0.1 1e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY53991.1 - 1.2e-16 61.9 1.7 2.3e-16 61.1 1.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KIY53991.1 - 1.6e-05 24.7 0.0 3.1e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 KIY53991.1 - 0.00085 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.14 KIY53991.1 - 0.002 16.9 0.0 0.011 14.5 0.0 2.1 3 1 1 4 4 4 1 Ndr family LIDHydrolase PF10230.9 KIY53991.1 - 0.0024 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 KIY53991.1 - 0.031 14.1 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3530 PF12048.8 KIY53991.1 - 0.054 12.9 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_2 PF02230.16 KIY53991.1 - 0.086 12.6 0.0 2 8.2 0.0 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF915 PF06028.11 KIY53991.1 - 0.1 11.9 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Pkinase PF00069.25 KIY53992.1 - 9.4e-21 74.3 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY53992.1 - 6.5e-06 25.6 0.0 7.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY53992.1 - 0.0059 16.0 0.1 0.021 14.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KIY53992.1 - 0.0086 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY53992.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY53992.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KIY53992.1 - 0.21 10.6 0.1 0.29 10.1 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 FGE-sulfatase PF03781.16 KIY53993.1 - 1.8e-19 70.3 1.2 2e-11 43.9 0.1 2.1 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KIY53993.1 - 2e-06 28.3 0.2 3.9e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 DinB superfamily DUF4479 PF14794.6 KIY53993.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) Pyridoxal_deC PF00282.19 KIY53995.1 - 2.8e-98 329.1 0.0 3.3e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIY53995.1 - 0.085 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V RrnaAD PF00398.20 KIY53995.1 - 0.19 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AAA PF00004.29 KIY53996.1 - 2.2e-54 183.4 0.0 2.7e-43 147.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KIY53996.1 - 6.9e-24 84.1 0.2 1.5e-23 82.9 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KIY53996.1 - 4.8e-14 51.9 0.8 1.1e-08 34.7 0.2 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KIY53996.1 - 2.2e-07 31.4 10.1 0.019 15.3 0.1 5.1 3 2 2 5 5 5 2 AAA ATPase domain RuvB_N PF05496.12 KIY53996.1 - 6.6e-06 25.9 0.0 0.0026 17.5 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY53996.1 - 4.4e-05 23.5 0.0 0.51 10.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIY53996.1 - 5.8e-05 23.1 0.0 0.37 10.8 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KIY53996.1 - 5.8e-05 23.6 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KIY53996.1 - 0.00016 21.9 6.6 1.1 9.6 0.1 5.1 3 2 1 4 4 3 1 AAA domain TIP49 PF06068.13 KIY53996.1 - 0.00032 20.0 0.0 0.066 12.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_19 PF13245.6 KIY53996.1 - 0.00048 20.5 0.0 0.027 14.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY53996.1 - 0.00061 19.7 3.7 2.4 8.1 1.0 4.1 3 1 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 KIY53996.1 - 0.001 19.1 0.0 0.24 11.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.14 KIY53996.1 - 0.0017 18.5 0.0 0.037 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KIY53996.1 - 0.0017 18.5 0.0 0.047 13.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KIY53996.1 - 0.0031 16.8 0.0 2.5 7.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 KIY53996.1 - 0.0038 16.8 2.2 1.2 8.7 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_7 PF12775.7 KIY53996.1 - 0.0043 16.6 0.0 0.63 9.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KIY53996.1 - 0.0045 17.4 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KIY53996.1 - 0.0066 15.8 0.1 0.63 9.4 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KIY53996.1 - 0.0067 16.7 0.6 6.9 6.9 0.1 3.1 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 KIY53996.1 - 0.011 15.5 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KIY53996.1 - 0.015 15.0 0.0 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KIY53996.1 - 0.02 14.7 0.0 1.3 8.9 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIY53996.1 - 0.022 14.5 0.0 3.8 7.2 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KIY53996.1 - 0.032 13.6 0.7 8.1 5.7 0.0 3.3 4 0 0 4 4 3 0 KaiC T2SSE PF00437.20 KIY53996.1 - 0.048 12.7 0.0 0.32 10.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 KIY53996.1 - 0.058 12.6 0.0 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.6 KIY53996.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Cytidylate kinase-like family Rad17 PF03215.15 KIY53996.1 - 0.062 13.2 0.1 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain PhoH PF02562.16 KIY53996.1 - 0.069 12.6 0.1 9.2 5.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 KIY53996.1 - 0.073 13.0 0.2 7.4 6.5 0.0 3.3 4 0 0 4 4 3 0 NTPase GCD14 PF08704.10 KIY53996.1 - 0.075 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit AAA_29 PF13555.6 KIY53996.1 - 0.095 12.5 0.2 5.5 6.8 0.1 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KIY53996.1 - 0.1 12.3 0.0 0.6 9.8 0.0 2.2 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 KIY53996.1 - 0.34 11.3 0.1 0.34 11.3 0.1 2.9 4 0 0 4 4 2 0 AAA domain 5-FTHF_cyc-lig PF01812.20 KIY53997.1 - 9.1e-32 110.4 0.0 1.4e-31 109.8 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Mito_carr PF00153.27 KIY53998.1 - 1.9e-59 197.6 3.5 1.6e-22 79.2 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIY53998.1 - 0.0032 16.7 0.4 0.032 13.4 0.0 2.4 3 0 0 3 3 3 1 Gammaproteobacterial serine protease TBPIP PF07106.13 KIY53999.1 - 6.6e-18 64.4 0.2 1.4e-17 63.3 0.2 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 KIY53999.1 - 0.00033 21.0 2.2 0.00065 20.0 2.0 1.6 2 0 0 2 2 2 1 Penicillinase repressor DUF4665 PF15679.5 KIY53999.1 - 0.00038 21.0 6.8 0.022 15.4 6.2 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4665) Phage_GP20 PF06810.11 KIY53999.1 - 0.013 15.3 5.2 0.028 14.2 5.2 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 UPF0242 PF06785.11 KIY53999.1 - 0.015 15.4 4.5 0.025 14.7 4.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Vps52 PF04129.12 KIY53999.1 - 0.017 13.9 0.2 0.02 13.6 0.2 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family GAS PF13851.6 KIY53999.1 - 0.026 13.9 4.3 0.044 13.1 4.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Vps5 PF09325.10 KIY53999.1 - 0.031 13.8 2.2 0.05 13.2 2.2 1.3 1 0 0 1 1 1 0 Vps5 C terminal like Baculo_PEP_C PF04513.12 KIY53999.1 - 0.035 14.1 2.2 0.069 13.2 2.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 KIY53999.1 - 0.11 12.7 4.5 0.2 11.9 3.6 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3391 PF11871.8 KIY53999.1 - 0.11 13.0 3.0 0.35 11.4 3.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF2730 PF10805.8 KIY53999.1 - 0.13 12.3 3.5 1.4 9.1 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) GIT_CC PF16559.5 KIY53999.1 - 2.3 8.1 6.6 5.5 6.9 0.1 2.4 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor adh_short PF00106.25 KIY54000.1 - 1.1e-38 132.7 0.3 1.5e-38 132.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY54000.1 - 4.6e-23 82.0 0.1 6.1e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY54000.1 - 0.00016 21.7 0.2 0.00027 20.9 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIY54000.1 - 0.0047 16.8 0.3 0.0082 16.1 0.3 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox_2 PF07992.14 KIY54000.1 - 0.0053 16.0 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 KIY54000.1 - 0.036 13.5 0.1 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIY54000.1 - 0.042 13.4 0.1 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family ApbA PF02558.16 KIY54000.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIY54000.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SAM_MT PF04445.13 KIY54000.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase SRR1 PF07985.12 KIY54001.1 - 2.6e-17 62.6 0.4 4.2e-17 61.9 0.4 1.4 1 0 0 1 1 1 1 SRR1 GIT_SHD PF08518.11 KIY54002.1 - 1.2e-26 92.0 3.9 6.1e-14 51.3 0.5 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF4686 PF15742.5 KIY54002.1 - 0.1 11.7 28.1 0.17 11.0 28.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) SpecificRecomb PF10136.9 KIY54002.1 - 0.21 9.8 4.6 0.48 8.7 4.6 1.5 1 0 0 1 1 1 0 Site-specific recombinase AIP3 PF03915.13 KIY54002.1 - 1.4 7.9 23.4 0.47 9.5 18.9 2.0 2 0 0 2 2 2 0 Actin interacting protein 3 DUF1664 PF07889.12 KIY54002.1 - 1.7 8.7 11.3 1.1 9.3 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KIY54002.1 - 2.9 6.7 29.3 2 7.2 14.8 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein XhlA PF10779.9 KIY54002.1 - 3.3 8.0 4.5 3.1 8.1 0.9 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Lebercilin PF15619.6 KIY54002.1 - 4.8 6.8 32.4 0.96 9.1 21.3 3.0 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 KIY54002.1 - 6.3 6.0 20.8 0.29 10.4 3.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Ras PF00071.22 KIY54003.1 - 3e-50 170.0 0.0 3.6e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY54003.1 - 6.5e-24 84.5 0.0 9.3e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY54003.1 - 1.7e-05 24.3 0.0 2.5e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIY54003.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KIY54003.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KIY54003.1 - 0.22 10.9 0.0 0.58 9.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Exo70 PF03081.15 KIY54004.1 - 0.015 14.4 0.1 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit LXG PF04740.12 KIY54004.1 - 0.053 13.2 0.5 0.59 9.8 0.1 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily Ank_4 PF13637.6 KIY54005.1 - 1.5e-13 50.9 0.1 1.4e-08 35.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY54005.1 - 3.7e-11 42.9 0.9 9.6e-08 32.1 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KIY54005.1 - 3.6e-09 36.1 0.2 7.2e-06 26.0 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIY54005.1 - 3e-08 33.8 0.3 3e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY54005.1 - 3.8e-08 33.8 0.0 3.5e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ubiq_cyt_C_chap PF03981.12 KIY54006.1 - 5.1e-23 81.7 0.0 2e-13 50.6 0.0 3.0 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone DUF3437 PF11919.8 KIY54007.1 - 0.041 13.8 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Herpes_U5 PF05999.11 KIY54007.1 - 0.046 12.5 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family Fe-S_biosyn PF01521.20 KIY54008.1 - 8.9e-13 48.4 0.0 3.2e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis SPRY PF00622.28 KIY54009.1 - 2e-10 40.8 0.0 3.6e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain zf-4CXXC_R1 PF10497.9 KIY54010.1 - 0.0012 19.1 9.8 0.0052 17.0 9.9 1.9 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Gpr1_Fun34_YaaH PF01184.19 KIY54011.1 - 4.6e-67 225.6 20.6 1.1e-44 152.5 13.5 2.0 2 0 0 2 2 2 2 GPR1/FUN34/yaaH family G-patch_2 PF12656.7 KIY54012.1 - 1.6e-21 76.1 0.1 1.6e-21 76.1 0.1 2.5 3 0 0 3 3 3 1 G-patch domain G-patch PF01585.23 KIY54012.1 - 0.066 13.1 0.2 0.19 11.6 0.2 1.8 1 0 0 1 1 1 0 G-patch domain YtxH PF12732.7 KIY54013.1 - 0.00025 21.5 26.9 0.021 15.4 4.0 3.1 1 1 1 2 2 2 1 YtxH-like protein Coiled-coil_56 PF09813.9 KIY54013.1 - 0.0018 18.3 0.8 0.0068 16.4 0.0 2.2 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 56 LEA_4 PF02987.16 KIY54013.1 - 0.005 16.9 4.9 0.005 16.9 4.9 3.4 3 0 0 3 3 3 1 Late embryogenesis abundant protein Apolipoprotein PF01442.18 KIY54013.1 - 0.0086 16.0 20.8 0.047 13.6 20.9 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Activator-TraM PF11657.8 KIY54013.1 - 0.023 14.5 6.0 0.023 14.5 6.0 2.1 1 1 1 2 2 2 0 Transcriptional activator TraM DUF5427 PF10310.9 KIY54013.1 - 0.43 9.5 23.5 0.57 9.1 23.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) HemX PF04375.14 KIY54013.1 - 0.58 9.4 9.1 0.047 13.0 3.6 1.8 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Gp-FAR-1 PF05823.12 KIY54013.1 - 0.59 10.5 8.2 2.7 8.3 8.2 1.9 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) V_ATPase_I PF01496.19 KIY54013.1 - 0.94 7.3 8.1 1.2 6.9 8.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2570 PF10828.8 KIY54013.1 - 1.1 9.1 5.9 0.23 11.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) SpoIIIAH PF12685.7 KIY54013.1 - 1.4 8.7 21.2 10 5.9 21.2 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF4199 PF13858.6 KIY54013.1 - 1.5 9.2 0.0 1.5 9.2 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) Phage_int_SAM_1 PF02899.17 KIY54016.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain NTP_transferase PF00483.23 KIY54017.1 - 4.5e-39 134.5 0.0 1.7e-38 132.6 0.0 1.9 3 0 0 3 3 3 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIY54017.1 - 2.1e-06 28.2 0.1 5e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 KIY54017.1 - 0.00043 20.2 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase DivIC PF04977.15 KIY54017.1 - 0.31 10.8 2.7 0.18 11.6 0.5 1.7 2 0 0 2 2 2 0 Septum formation initiator MCCD1 PF15707.5 KIY54018.1 - 0.19 12.2 4.4 0.79 10.2 3.8 2.5 1 1 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 YebO PF13974.6 KIY54018.1 - 1.5 9.0 5.2 5.9 7.0 5.2 2.0 1 0 0 1 1 1 0 YebO-like protein Retrotrans_gag PF03732.17 KIY54019.1 - 3.8e-05 23.9 0.5 7.1e-05 23.0 0.5 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Glyco_hydro_3_C PF01915.22 KIY54022.1 - 8.1e-49 166.3 0.0 1.6e-48 165.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY54022.1 - 4.7e-34 118.2 0.0 5.4e-33 114.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY54022.1 - 1.4e-18 66.8 0.0 2.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 KIY54022.1 - 0.2 12.0 2.8 0.62 10.4 0.0 2.9 3 0 0 3 3 3 0 CARDB MFS_1 PF07690.16 KIY54024.1 - 2.1e-33 115.7 29.3 2.1e-33 115.7 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.12 KIY54024.1 - 0.0063 16.2 0.1 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF697) Phage_holin_5_2 PF16079.5 KIY54024.1 - 0.61 10.5 0.0 0.61 10.5 0.0 4.5 5 0 0 5 5 5 0 Phage holin family Hol44, in holin superfamily V NAD_binding_4 PF07993.12 KIY54025.1 - 7.9e-25 87.5 0.0 1.7e-24 86.4 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 KIY54025.1 - 1.1e-14 53.8 0.0 1.4e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KIY54025.1 - 1.8e-06 27.6 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIY54025.1 - 0.098 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KIY54025.1 - 0.18 12.2 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 KIY54027.1 - 1.1e-41 143.1 0.0 2.1e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIY54027.1 - 3.6e-22 78.3 0.1 8.6e-22 77.0 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KIY54027.1 - 9.5e-15 54.8 0.0 3e-14 53.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain p450 PF00067.22 KIY54029.1 - 1.1e-34 120.0 0.0 1.5e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KIY54030.1 - 4.4e-56 190.4 0.0 5.6e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY54030.1 - 3.2e-32 112.0 0.0 5.5e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY54030.1 - 6.2e-05 23.2 0.0 0.00025 21.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIY54030.1 - 0.00011 21.4 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY54030.1 - 0.00024 20.5 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY54030.1 - 0.00036 20.2 0.1 0.0017 18.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIY54030.1 - 0.00083 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KIY54030.1 - 0.0049 16.0 0.0 0.012 14.8 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY54030.1 - 0.0049 16.2 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KIY54030.1 - 0.015 13.8 0.0 0.035 12.6 0.0 1.5 2 0 0 2 2 2 0 GDP dissociation inhibitor HI0933_like PF03486.14 KIY54030.1 - 0.071 11.8 0.0 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 KIY54030.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Chordopox_G2 PF05796.12 KIY54030.1 - 0.19 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus protein G2 DUF2953 PF11167.8 KIY54030.1 - 0.53 10.4 1.8 4.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) Pkinase PF00069.25 KIY54032.1 - 1.3e-73 247.6 0.2 1.3e-73 247.6 0.2 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY54032.1 - 2.5e-52 177.7 1.5 3.5e-52 177.3 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KIY54032.1 - 2.7e-22 78.9 0.0 6.6e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KIY54032.1 - 2.1e-06 27.3 0.0 3.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY54032.1 - 6.2e-06 25.2 1.4 1.4e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KIY54032.1 - 7.1e-05 21.9 1.5 0.00012 21.2 1.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY54032.1 - 0.0004 20.4 2.7 0.022 14.7 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family PH PF00169.29 KIY54032.1 - 0.002 18.6 0.1 0.0059 17.1 0.1 1.8 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.11 KIY54032.1 - 0.027 13.5 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KIY54032.1 - 0.04 13.3 0.3 0.16 11.3 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S13 PF00416.22 KIY54032.1 - 0.056 13.8 0.5 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S13/S18 DUF2345 PF10106.9 KIY54033.1 - 0.00052 19.9 4.0 0.00075 19.4 4.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) Pico_P2A PF00947.19 KIY54033.1 - 0.11 12.6 0.4 0.11 12.6 0.4 2.7 1 1 1 2 2 2 0 Picornavirus core protein 2A T6SS_VasJ PF16989.5 KIY54033.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ IrmA PF18673.1 KIY54033.1 - 0.19 11.9 1.9 51 4.1 0.2 3.9 1 1 3 4 4 4 0 interleukin receptor mimic protein A Ntox14 PF15522.6 KIY54033.1 - 0.52 9.7 6.3 1.1 8.7 0.9 3.0 1 1 2 3 3 3 0 Novel toxin 14 KDZ PF18758.1 KIY54035.1 - 3.3e-56 190.4 3.2 3.9e-56 190.2 3.2 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Milton PF12448.8 KIY54037.1 - 1.1 9.4 9.6 0.42 10.7 6.8 1.7 2 0 0 2 2 2 0 Kinesin associated protein # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fistulina_hepatica_ATCC_64428-Fishe1/GCA_000934395.1_Fishe1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fistulina_hepatica_ATCC_64428-Fishe1/GCA_000934395.1_Fishe1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fistulina_hepatica_ATCC_64428-Fishe1/GCA_000934395.1_Fishe1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fistulina_hepatica_ATCC_64428-Fishe1/GCA_000934395.1_Fishe1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 20:16:18 2019 # [ok]