# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Methyltransf_2 PF00891.13 CCL98008.1 - 2.1e-24 86.0 0.1 2.6e-24 85.7 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase YscK PF06578.7 CCL98008.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) MFS_1 PF07690.11 CCL98009.1 - 2e-31 109.0 41.7 7.6e-22 77.4 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCL98009.1 - 8.9e-06 24.3 26.4 0.031 12.6 3.9 3.8 2 2 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 CCL98009.1 - 8.1e-05 21.3 24.0 8.4e-05 21.3 5.4 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 CCL98009.1 - 0.00013 20.3 0.6 0.00013 20.3 0.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1256 PF06866.6 CCL98009.1 - 0.2 10.8 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) DAO PF01266.19 CCL98010.1 - 9.3e-49 166.2 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCL98010.1 - 8.6e-10 38.5 0.0 2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCL98010.1 - 1e-07 32.0 0.0 7.2e-05 22.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCL98010.1 - 2.4e-05 23.5 0.0 6.1e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 CCL98010.1 - 0.00018 20.7 0.0 0.00083 18.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CCL98010.1 - 0.00041 20.4 0.0 0.0007 19.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCL98010.1 - 0.0006 20.1 0.0 0.038 14.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCL98010.1 - 0.002 17.9 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 CCL98010.1 - 0.0021 16.9 0.1 0.25 10.1 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCL98010.1 - 0.0034 16.3 0.0 0.0066 15.3 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 CCL98010.1 - 0.0058 16.3 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CCL98010.1 - 0.09 12.1 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CCL98010.1 - 0.19 11.7 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Nucleoplasmin PF03066.10 CCL98011.1 - 0.038 13.5 7.2 0.067 12.7 5.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 CCL98011.1 - 0.34 8.7 6.3 0.51 8.2 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CCL98011.1 - 6.1 5.2 22.4 0.026 13.0 8.0 1.9 1 1 1 2 2 2 0 Daxx Family IncA PF04156.9 CCL98012.1 - 2.5 7.6 6.6 10 5.6 4.2 2.4 1 1 0 1 1 1 0 IncA protein Methyltransf_2 PF00891.13 CCL98013.1 - 1.4e-35 122.6 0.0 1.9e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 CCL98013.1 - 0.00019 21.9 0.0 0.00042 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCL98013.1 - 0.0045 16.5 0.0 0.017 14.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCL98013.1 - 0.0061 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCL98013.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_transf_15 PF01793.11 CCL98014.1 - 1.2e-136 454.9 6.1 1.5e-136 454.6 4.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF751 PF05421.6 CCL98014.1 - 0.52 10.6 3.0 1.2 9.4 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF751) SMP PF04927.7 CCL98016.1 - 0.024 14.5 0.4 0.04 13.8 0.3 1.5 1 1 0 1 1 1 0 Seed maturation protein DUF3729 PF12526.3 CCL98016.1 - 0.43 11.9 4.3 0.5 11.7 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) SMP PF04927.7 CCL98017.1 - 0.084 12.8 8.7 0.13 12.1 5.9 1.5 1 1 0 1 1 1 0 Seed maturation protein SET PF00856.23 CCL98018.1 - 4.4e-11 43.3 0.0 1.1e-09 38.8 0.0 2.4 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.1 CCL98018.1 - 0.035 14.0 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_transf_15 PF01793.11 CCL98020.1 - 4e-117 390.8 5.4 5.2e-117 390.4 3.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Bromodomain PF00439.20 CCL98021.1 - 2e-20 72.4 0.0 4.1e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Sec7_N PF12783.2 CCL98022.1 - 2e-35 121.6 0.0 8.3e-35 119.6 0.0 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCL98022.1 - 5.8e-05 22.5 0.0 0.0015 18.0 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Ank_2 PF12796.2 CCL98023.1 - 3.7e-15 56.0 0.0 7.1e-15 55.1 0.0 1.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCL98023.1 - 5.3e-14 51.2 0.1 6.2e-09 35.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCL98023.1 - 1.1e-13 50.9 0.6 6.2e-09 35.8 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCL98023.1 - 1.8e-11 44.2 2.7 9.8e-06 25.9 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCL98023.1 - 1e-08 34.5 0.0 4.4e-07 29.5 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeat RHS PF03527.9 CCL98023.1 - 0.11 12.2 0.1 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 RHS protein Homeobox PF00046.24 CCL98024.1 - 8.9e-06 25.2 1.2 2.1e-05 24.0 0.9 1.7 1 0 0 1 1 1 1 Homeobox domain DUF1178 PF06676.6 CCL98024.1 - 0.19 11.8 1.5 0.35 11.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DUF4544 PF15077.1 CCL98025.1 - 0.3 10.5 3.2 0.35 10.3 1.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4544) Acid_PPase PF12689.2 CCL98026.1 - 1.6e-59 200.3 0.0 1.9e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 CCL98026.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase RHH_3 PF12651.2 CCL98026.1 - 0.11 12.2 0.7 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix domain DUF1726 PF08351.6 CCL98027.1 - 0.034 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) NAD_binding_4 PF07993.7 CCL98028.1 - 6.9e-27 93.9 0.0 8.6e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CCL98028.1 - 2e-09 37.2 0.0 4.5e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CCL98028.1 - 0.0045 15.9 0.4 0.7 8.7 0.1 2.5 2 1 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 CCL98028.1 - 0.023 14.6 0.2 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 CCL98028.1 - 0.042 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 CCL98028.1 - 0.058 12.0 0.0 0.72 8.4 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCL98029.1 - 2.4e-32 111.8 0.0 2.9e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CCL98029.1 - 2.3e-09 37.0 0.0 3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CCL98029.1 - 6.1e-05 22.0 0.5 0.01 14.7 0.2 2.5 2 1 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 CCL98029.1 - 0.0045 15.7 0.0 0.0086 14.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCL98029.1 - 0.023 14.6 0.2 0.077 12.9 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 CCL98030.1 - 4.8e-30 104.4 41.9 6.4e-30 104.0 29.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Colicin_im PF03857.8 CCL98030.1 - 0.0017 18.1 0.7 0.0043 16.7 0.0 2.0 2 0 0 2 2 2 1 Colicin immunity protein Abhydrolase_6 PF12697.2 CCL98031.1 - 4.9e-29 101.8 1.4 5.8e-29 101.5 0.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCL98031.1 - 5e-17 61.9 0.2 1.8e-16 60.1 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98031.1 - 3.7e-13 49.5 0.6 1.2e-12 47.9 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCL98031.1 - 0.00032 20.5 0.1 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 CCL98031.1 - 0.028 13.8 0.0 11 5.4 0.0 3.0 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase IIGP PF05049.8 CCL98032.1 - 7.8e-20 71.0 0.0 1.1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MIP-T3 PF10243.4 CCL98032.1 - 6.1e-07 28.2 16.1 6.1e-07 28.2 11.2 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 MMR_HSR1 PF01926.18 CCL98032.1 - 8.4e-06 25.7 0.0 2.1e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCL98032.1 - 0.00089 18.4 0.0 0.002 17.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CCL98032.1 - 0.023 15.1 0.0 0.06 13.8 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 CCL98032.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCL98032.1 - 0.059 13.6 0.1 0.059 13.6 0.1 3.0 2 1 0 2 2 1 0 ABC transporter DUF572 PF04502.8 CCL98032.1 - 0.17 11.0 25.7 0.34 10.1 17.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Borrelia_P83 PF05262.6 CCL98032.1 - 1.3 7.2 30.7 2 6.6 21.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Asp-B-Hydro_N PF05279.6 CCL98032.1 - 1.3 8.7 33.1 2.5 7.9 22.9 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PLRV_ORF5 PF01690.12 CCL98032.1 - 4.5 6.3 18.5 7.5 5.5 12.8 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Z1 PF10593.4 CCL98032.1 - 9.1 5.4 13.0 0.24 10.5 3.2 2.3 1 1 1 2 2 2 0 Z1 domain Sin3_corepress PF08295.7 CCL98034.1 - 2e-34 117.3 0.2 6.8e-34 115.6 0.2 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 CCL98034.1 - 4.2e-29 99.8 1.2 1.6e-15 56.4 0.0 4.5 3 1 0 3 3 3 3 Paired amphipathic helix repeat Vfa1 PF08432.5 CCL98034.1 - 1.1 9.2 19.9 0.021 14.8 7.9 2.5 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 CPSF100_C PF13299.1 CCL98034.1 - 3.4 7.8 10.5 0.63 10.2 3.7 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal IF4E PF01652.13 CCL98035.1 - 2.3e-46 157.3 0.0 3.2e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.6 CCL98035.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) PAP1 PF08601.5 CCL98036.1 - 2.1 7.9 11.2 2.6 7.6 7.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 WW PF00397.21 CCL98037.1 - 4e-07 29.7 3.9 4e-07 29.7 2.7 2.1 2 0 0 2 2 2 1 WW domain Metallophos PF00149.23 CCL98038.1 - 1e-41 142.5 0.1 1.5e-41 142.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4646 PF15496.1 CCL98039.1 - 1.5e-36 125.1 0.0 2.6e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Apt1 PF10351.4 CCL98039.1 - 0.031 13.1 0.7 0.045 12.6 0.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.9 CCL98039.1 - 0.051 11.6 12.6 0.07 11.1 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CCL98039.1 - 0.51 9.6 6.3 1.6 8.0 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4646 PF15496.1 CCL98040.1 - 7.5e-36 122.8 0.0 1.6e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) PAP2 PF01569.16 CCL98041.1 - 2.5e-18 65.9 6.8 6.8e-18 64.5 4.7 1.8 1 0 0 1 1 1 1 PAP2 superfamily bZIP_2 PF07716.10 CCL98042.1 - 0.0014 18.3 6.9 0.21 11.4 3.1 2.6 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 CCL98042.1 - 0.027 14.4 9.1 0.75 9.7 3.8 2.6 2 0 0 2 2 2 0 bZIP transcription factor Catalase-rel PF06628.7 CCL98042.1 - 0.085 12.7 0.2 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Catalase-related immune-responsive ATP-grasp_2 PF08442.5 CCL98042.1 - 0.16 11.3 0.7 0.36 10.1 0.5 1.5 1 0 0 1 1 1 0 ATP-grasp domain TMF_DNA_bd PF12329.3 CCL98042.1 - 1.1 9.0 5.0 0.19 11.5 0.3 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GST_N_3 PF13417.1 CCL98044.1 - 1.1e-12 47.9 0.1 2e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCL98044.1 - 9.6e-10 38.3 0.0 2.8e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCL98044.1 - 0.0012 19.0 0.0 0.086 13.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CCL98044.1 - 0.0033 17.3 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 CCL98044.1 - 0.15 12.0 0.9 0.41 10.5 0.6 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEAD PF00270.24 CCL98046.1 - 6.9e-16 58.2 0.0 1.5e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCL98046.1 - 3.9e-14 52.2 0.1 6.1e-13 48.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCL98046.1 - 3.2e-05 23.8 0.0 6.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Syntaxin_2 PF14523.1 CCL98046.1 - 0.0095 15.9 1.3 0.019 14.9 0.3 2.0 2 0 0 2 2 2 1 Syntaxin-like protein RQC PF09382.5 CCL98046.1 - 0.0095 15.6 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 RQC domain DUF870 PF05912.6 CCL98046.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) Mnd1 PF03962.10 CCL98046.1 - 0.39 10.3 2.9 0.82 9.2 2.0 1.4 1 0 0 1 1 1 0 Mnd1 family Lebercilin PF15619.1 CCL98046.1 - 1.2 8.4 7.6 0.17 11.2 1.8 1.9 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CPSF_A PF03178.10 CCL98048.1 - 3.6e-72 243.1 0.0 9.7e-72 241.7 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CCL98048.1 - 2.2e-12 45.8 0.0 1.3e-11 43.4 0.0 2.2 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 CCL98049.1 - 3.2e-16 58.5 7.5 0.00019 21.1 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 CCL98049.1 - 4.5e-08 32.9 0.0 4.5e-08 32.9 0.0 2.6 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Apc4_WD40 PF12894.2 CCL98049.1 - 0.034 13.6 0.1 7.9 6.0 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.10 CCL98049.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Prp18 domain HrcA PF01628.16 CCL98049.1 - 0.07 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 HrcA protein C terminal domain Sec16_C PF12931.2 CCL98049.1 - 0.086 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Sec63 PF02889.11 CCL98051.1 - 8.3e-181 600.1 0.0 2.4e-89 299.6 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CCL98051.1 - 5.1e-51 172.5 0.4 2.2e-28 98.8 0.1 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CCL98051.1 - 6.3e-14 52.2 0.1 1.5e-09 37.9 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCL98051.1 - 1.7e-09 37.4 0.0 1.9e-08 34.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCL98051.1 - 1.2e-07 31.8 0.1 0.0035 17.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 CCL98051.1 - 3.2e-05 23.2 0.0 0.0069 15.6 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein T2SE PF00437.15 CCL98051.1 - 0.0038 16.1 0.0 0.086 11.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein UDG PF03167.14 CCL98052.1 - 1.1e-16 60.6 0.0 6.5e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily RRM_1 PF00076.17 CCL98053.1 - 8.6e-25 86.1 0.0 5.2e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL98053.1 - 5.2e-20 71.0 0.0 5.8e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL98053.1 - 5e-18 64.8 0.0 2.4e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCL98053.1 - 0.0034 17.1 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 Limkain b1 Calcipressin PF04847.7 CCL98053.1 - 0.0099 15.4 0.1 0.29 10.7 0.0 2.2 2 0 0 2 2 2 1 Calcipressin Malic_M PF03949.10 CCL98054.1 - 9.5e-73 244.8 0.0 1.3e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CCL98054.1 - 5e-54 182.6 0.0 7.1e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ApoC-I PF04691.7 CCL98054.1 - 0.054 13.1 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) LysM PF01476.15 CCL98055.1 - 2e-12 46.7 0.0 3.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain MARVEL PF01284.18 CCL98056.1 - 2.1e-09 37.3 23.4 3.6e-09 36.5 16.2 1.4 1 1 0 1 1 1 1 Membrane-associating domain RdRP PF05183.7 CCL98058.1 - 1.3e-113 380.7 0.0 1.7e-113 380.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase p450 PF00067.17 CCL98059.1 - 7.2e-26 90.7 0.0 2.9e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 CorA PF01544.13 CCL98060.1 - 1.1e-11 44.3 1.6 3.5e-07 29.5 0.7 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Methyltransf_31 PF13847.1 CCL98061.1 - 1.2e-19 70.4 0.0 1.5e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCL98061.1 - 4.8e-19 68.6 0.0 6.7e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCL98061.1 - 1.2e-14 54.4 0.0 2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCL98061.1 - 5.5e-14 52.4 0.0 1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCL98061.1 - 1.3e-12 48.3 0.0 2.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCL98061.1 - 2e-11 44.1 0.1 3.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCL98061.1 - 6.9e-11 41.6 0.1 5.4e-10 38.7 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CCL98061.1 - 1.4e-08 34.7 0.0 3.2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CCL98061.1 - 1.5e-06 28.3 0.0 2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 CCL98061.1 - 8e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CCL98061.1 - 0.00032 19.9 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CCL98061.1 - 0.00055 19.6 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 CCL98061.1 - 0.00055 18.8 0.0 0.0013 17.6 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme tRNA_U5-meth_tr PF05958.6 CCL98061.1 - 0.00096 17.9 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase NodS PF05401.6 CCL98061.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 CCL98061.1 - 0.024 13.6 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase TPMT PF05724.6 CCL98061.1 - 0.024 14.0 0.0 0.034 13.5 0.0 1.4 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DREV PF05219.7 CCL98061.1 - 0.027 13.3 0.0 0.052 12.4 0.0 1.7 2 1 0 2 2 2 0 DREV methyltransferase CmcI PF04989.7 CCL98061.1 - 0.044 13.1 0.1 0.14 11.4 0.0 1.8 1 1 1 2 2 2 0 Cephalosporin hydroxylase Sugar_tr PF00083.19 CCL98062.1 - 4.6e-115 384.7 16.8 6.1e-115 384.3 11.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Proteasome PF00227.21 CCL98062.1 - 1e-55 187.9 0.1 5.8e-55 185.5 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit Ribonuc_L-PSP PF01042.16 CCL98062.1 - 1.4e-38 131.3 0.0 2.8e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.11 CCL98062.1 - 3.5e-16 58.8 37.9 6.3e-16 58.0 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Proteasome_A_N PF10584.4 CCL98062.1 - 3.2e-12 45.5 0.4 2.7e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature G-alpha PF00503.15 CCL98063.1 - 9.7e-99 330.6 0.0 1.6e-83 280.5 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 CCL98063.1 - 9.9e-08 31.4 0.2 0.015 14.5 0.0 3.2 3 0 0 3 3 3 3 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCL98063.1 - 0.0071 15.5 0.5 3.8 6.5 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CCL98063.1 - 0.018 14.5 0.1 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CCL98063.1 - 0.024 14.0 0.0 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DASH_Ask1 PF08655.5 CCL98065.1 - 8.2e-22 76.8 0.0 1.4e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Inositol_P PF00459.20 CCL98067.1 - 7.3e-66 222.2 0.0 8.6e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family p450 PF00067.17 CCL98068.1 - 6.3e-47 160.1 0.0 7e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCL98069.1 - 7.6e-52 176.3 0.0 9.6e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCL98070.1 - 7.1e-51 173.1 0.0 1.2e-50 172.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 MASE1 PF05231.9 CCL98071.1 - 0.88 8.5 14.9 31 3.4 10.3 2.1 1 1 0 1 1 1 0 MASE1 YqzM PF14141.1 CCL98071.1 - 7.8 6.3 9.4 32 4.4 0.0 2.6 2 0 0 2 2 2 0 YqzM-like protein Dor1 PF04124.7 CCL98072.1 - 1.3e-60 204.7 2.7 2.1e-60 203.9 1.9 1.4 1 1 0 1 1 1 1 Dor1-like family Vps51 PF08700.6 CCL98072.1 - 2.7e-07 30.3 0.2 7.6e-07 28.8 0.0 1.8 1 1 1 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 CCL98072.1 - 1.8e-05 24.5 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 Baculo_PEP_C PF04513.7 CCL98072.1 - 0.0066 16.2 2.3 0.014 15.2 0.6 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Med21 PF11221.3 CCL98072.1 - 0.015 15.2 0.2 0.11 12.4 0.0 2.6 3 0 0 3 3 3 0 Subunit 21 of Mediator complex Zw10 PF06248.8 CCL98072.1 - 0.048 11.8 0.1 0.068 11.3 0.0 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 COG5 PF10392.4 CCL98072.1 - 0.26 11.2 4.6 0.22 11.5 1.2 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 TRI5 PF06330.6 CCL98073.1 - 4.7e-14 51.8 0.0 6.6e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF3591 PF12157.3 CCL98075.1 - 2.8e-169 563.3 0.4 2.8e-169 563.3 0.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CCL98075.1 - 0.00018 21.0 2.7 0.00046 19.8 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle PA28_beta PF02252.13 CCL98076.1 - 1.9e-39 134.5 0.3 2.7e-39 134.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit WD40 PF00400.27 CCL98077.1 - 9.9e-25 85.4 7.9 4.3e-08 32.7 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCL98077.1 - 2.1e-17 62.7 0.0 5.4e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex MAPEG PF01124.13 CCL98078.1 - 2.8e-21 75.4 0.7 3.5e-21 75.1 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Transthyretin PF00576.16 CCL98080.1 - 8e-31 106.2 0.2 2.1e-30 104.8 0.2 1.6 1 1 0 1 1 1 1 HIUase/Transthyretin family MG1 PF11974.3 CCL98080.1 - 0.059 13.9 0.0 0.078 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain Nop52 PF05997.7 CCL98081.1 - 1e-62 211.3 0.0 1.5e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 CCL98081.1 - 5.8e-06 25.7 0.0 3.5e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II RabGAP-TBC PF00566.13 CCL98082.1 - 1.8e-27 96.2 0.0 2.4e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Spc97_Spc98 PF04130.8 CCL98083.1 - 5.5e-66 223.0 0.0 7.8e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Pyrophosphatase PF00719.14 CCL98084.1 - 1.1e-54 184.1 0.1 1.4e-54 183.8 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase I-set PF07679.11 CCL98085.1 - 0.0032 17.2 0.0 0.76 9.6 0.0 4.4 5 0 0 5 5 5 1 Immunoglobulin I-set domain Histone PF00125.19 CCL98086.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCL98086.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CCL98086.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CCL98086.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CCL98086.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CCL98086.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FAD_binding_3 PF01494.14 CCL98087.1 - 1.1e-24 87.1 1.0 1.7e-22 79.9 0.7 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCL98087.1 - 5.1e-05 23.2 1.4 0.00017 21.5 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CCL98087.1 - 9e-05 21.7 1.3 0.2 10.6 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 CCL98087.1 - 0.011 14.2 4.7 0.24 9.8 2.8 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 CCL98087.1 - 0.017 15.4 2.8 0.042 14.2 1.7 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCL98087.1 - 0.022 13.8 2.8 0.029 13.4 0.8 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 CCL98087.1 - 0.027 14.3 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCL98087.1 - 0.047 13.4 2.5 2.1 8.1 0.4 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CCL98087.1 - 0.054 13.1 0.9 0.52 9.9 0.4 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 CCL98087.1 - 0.061 12.1 0.0 0.12 11.1 0.0 1.4 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.19 CCL98087.1 - 0.094 11.6 8.1 0.081 11.8 2.7 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCL98087.1 - 2.7 6.7 5.9 0.73 8.6 2.0 1.6 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 CCL98087.1 - 9.4 4.9 6.0 18 4.0 4.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_transf_22 PF03901.12 CCL98089.1 - 9.2e-82 275.2 15.5 1.5e-49 169.1 3.1 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family SLY PF12485.3 CCL98090.1 - 0.059 13.5 0.3 0.059 13.5 0.2 3.0 3 0 0 3 3 3 0 Lymphocyte signaling adaptor protein PAH PF02671.16 CCL98092.1 - 6.1e-39 131.3 5.6 1.7e-15 56.3 1.0 3.4 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CCL98092.1 - 9.5e-33 111.9 0.0 1.8e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Sin3 family co-repressor SH3_1 PF00018.23 CCL98093.1 - 3e-11 42.5 0.1 5.3e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCL98093.1 - 8.9e-10 38.0 0.0 1.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCL98093.1 - 1.1e-09 37.6 0.0 2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CCL98093.1 - 0.017 15.3 0.1 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain PgaD PF13994.1 CCL98093.1 - 6.5 6.2 6.8 0.93 8.9 1.4 1.9 1 1 0 2 2 2 0 PgaD-like protein zf-C3HC4_2 PF13923.1 CCL98094.1 - 3.1e-10 39.8 11.0 5e-10 39.2 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCL98094.1 - 2.1e-09 36.8 8.3 3.8e-09 36.0 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCL98094.1 - 6.6e-08 32.2 9.9 1.1e-07 31.5 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CCL98094.1 - 2.6e-06 27.2 10.4 4.4e-06 26.4 7.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCL98094.1 - 3.5e-06 26.6 4.4 3.9e-06 26.4 2.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CCL98094.1 - 6.6e-06 25.7 6.4 1.1e-05 25.0 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCL98094.1 - 3.1e-05 23.5 7.1 6.1e-05 22.6 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 CCL98094.1 - 0.024 14.1 6.1 0.047 13.2 4.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 CCL98094.1 - 0.035 14.2 6.4 0.088 12.9 4.1 1.9 2 1 0 2 2 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 CCL98094.1 - 0.049 13.1 9.0 0.11 12.0 6.3 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 CCL98094.1 - 0.86 9.4 3.6 2.5 7.9 2.5 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein NpwBP PF12622.2 CCL98095.1 - 1.7e-14 54.0 10.0 1.7e-14 54.0 6.9 5.4 4 1 0 4 4 4 1 mRNA biogenesis factor Wbp11 PF09429.5 CCL98095.1 - 6.8e-14 51.6 6.5 6.8e-14 51.6 4.5 2.2 2 0 0 2 2 2 1 WW domain binding protein 11 HIT PF01230.18 CCL98098.1 - 1.1e-24 86.7 0.0 1.5e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CCL98098.1 - 1.1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding LRR_4 PF12799.2 CCL98099.1 - 0.11 12.1 0.0 0.75 9.4 0.0 2.5 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Kdo PF06293.9 CCL98100.1 - 0.0025 16.9 0.1 0.0038 16.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CCL98100.1 - 0.017 14.2 0.0 0.047 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 CCL98100.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Metallophos PF00149.23 CCL98101.1 - 1e-07 31.5 7.7 5.4e-07 29.2 5.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCL98101.1 - 3.2e-05 23.8 0.0 0.00013 21.8 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MscS_TM PF12794.2 CCL98102.1 - 0.027 13.0 2.8 0.041 12.5 1.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF221 PF02714.10 CCL98103.1 - 5.8e-12 45.1 14.8 7.6e-12 44.7 8.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF221 DUF3779 PF12621.3 CCL98103.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CCL98103.1 - 0.0022 18.4 0.0 0.0078 16.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Sec1 PF00995.18 CCL98104.1 - 1.3e-135 453.2 0.0 1.6e-135 452.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Phage_Mu_Gam PF07352.7 CCL98104.1 - 0.0097 15.4 0.2 0.032 13.7 0.1 1.9 2 0 0 2 2 2 1 Bacteriophage Mu Gam like protein SPO11_like PF03533.9 CCL98104.1 - 0.026 14.3 0.3 5.6 6.9 0.2 2.9 2 0 0 2 2 2 0 SPO11 homologue Bax1-I PF01027.15 CCL98105.1 - 1.5e-33 116.1 10.5 1.5e-33 116.1 7.3 1.7 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Cation_ATPase_C PF00689.16 CCL98105.1 - 0.031 13.8 1.4 0.068 12.7 1.0 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus WD40 PF00400.27 CCL98106.1 - 3.6e-44 147.1 18.1 7.1e-09 35.2 0.0 7.5 6 1 1 7 7 7 7 WD domain, G-beta repeat LisH PF08513.6 CCL98106.1 - 1.2e-05 24.8 0.0 2.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 LisH Nbas_N PF15492.1 CCL98106.1 - 0.011 14.8 0.1 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 CCL98106.1 - 0.019 13.2 0.0 3.8 5.6 0.0 2.8 3 0 0 3 3 3 0 Cytochrome D1 heme domain WD40 PF00400.27 CCL98107.1 - 1.4e-23 81.8 13.1 9.3e-08 31.6 0.8 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CCL98107.1 - 0.026 12.8 1.2 7 4.8 0.0 3.3 3 0 0 3 3 3 0 Cytochrome D1 heme domain Sigma70_r3 PF04539.11 CCL98107.1 - 0.089 12.6 0.1 0.089 12.6 0.1 2.2 3 0 0 3 3 3 0 Sigma-70 region 3 Sushi PF00084.15 CCL98107.1 - 0.11 12.8 0.6 4.5 7.7 0.1 2.6 2 0 0 2 2 2 0 Sushi domain (SCR repeat) RicinB_lectin_2 PF14200.1 CCL98108.1 - 0.00043 20.6 0.0 0.0027 18.0 0.0 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CCL98108.1 - 0.13 12.2 0.0 0.47 10.4 0.0 1.8 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Arginase PF00491.16 CCL98109.1 - 9.4e-85 284.2 0.1 1.2e-84 283.9 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 CCL98109.1 - 0.095 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain SUR7 PF06687.7 CCL98110.1 - 2.6e-21 76.1 13.4 3.6e-21 75.7 9.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCL98110.1 - 0.27 10.9 16.6 0.49 10.0 11.4 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CCL98110.1 - 1.7 8.2 12.1 3.2 7.3 8.4 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF4064 PF13273.1 CCL98110.1 - 3.9 7.6 7.5 4.2 7.5 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Acetyltransf_3 PF13302.1 CCL98111.1 - 7.4e-15 55.3 0.0 1.2e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCL98111.1 - 3e-05 23.9 0.1 9e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CCL98111.1 - 0.015 15.2 0.0 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCL98111.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.22 CCL98112.1 - 2e-63 213.2 0.2 3.1e-63 212.6 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCL98112.1 - 1.3e-38 131.2 0.0 4.6e-38 129.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CCL98112.1 - 4.7e-22 77.6 0.0 9.5e-22 76.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCL98112.1 - 2.5e-13 49.6 0.0 5.8e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCL98112.1 - 9.8e-12 44.8 0.0 4.9e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCL98112.1 - 3e-06 27.1 0.2 6.2e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCL98112.1 - 0.11 13.0 0.2 0.24 11.9 0.1 1.6 1 0 0 1 1 1 0 Miro-like protein APH PF01636.18 CCL98113.1 - 8e-12 45.3 0.5 1.1e-11 44.9 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CCL98113.1 - 0.013 14.6 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 CCL98113.1 - 0.098 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PI-PLC-X PF00388.14 CCL98115.1 - 0.0017 17.7 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF512 PF04459.7 CCL98115.1 - 0.036 13.1 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) FAR1 PF03101.10 CCL98116.1 - 0.079 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Utp11 PF03998.8 CCL98117.1 - 2.4e-60 204.3 17.8 4.1e-60 203.6 12.3 1.4 1 1 0 1 1 1 1 Utp11 protein VHS PF00790.14 CCL98118.1 - 4.4e-23 81.4 0.1 1.5e-22 79.7 0.1 2.0 1 1 0 1 1 1 1 VHS domain GAT PF03127.9 CCL98118.1 - 3.9e-06 26.7 0.5 9.6e-06 25.5 0.4 1.6 1 0 0 1 1 1 1 GAT domain CAF-1_p150 PF11600.3 CCL98118.1 - 0.45 9.8 30.0 1.5 8.1 20.8 1.9 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 CCL98118.1 - 0.85 7.2 7.3 1 6.9 5.1 1.2 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 CCL98118.1 - 5.8 6.2 14.4 0.043 13.1 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RNA_polI_A34 PF08208.6 CCL98118.1 - 6.1 6.4 18.1 15 5.1 12.6 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 tRNA-synt_2b PF00587.20 CCL98119.1 - 4.9e-28 97.8 0.0 6.7e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCL98119.1 - 1.5e-05 24.9 0.5 2.9e-05 24.0 0.4 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Rep_fac_C PF08542.6 CCL98120.1 - 3.3e-22 78.2 0.0 7.2e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 CCL98120.1 - 2.3e-10 40.7 0.0 4.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCL98120.1 - 6.2e-10 38.9 0.1 1.2e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 CCL98120.1 - 1.9e-06 27.7 0.0 9.4e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCL98120.1 - 0.00068 19.7 0.0 0.74 9.9 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_3 PF07726.6 CCL98120.1 - 0.00075 19.1 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CCL98120.1 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 CCL98120.1 - 0.0041 15.8 0.9 0.2 10.2 0.1 2.6 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCL98120.1 - 0.012 15.6 0.0 0.16 11.9 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain DNA_pol3_delta PF06144.8 CCL98120.1 - 0.052 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ParA PF10609.4 CCL98121.1 - 3.6e-32 110.0 0.1 5.8e-32 109.4 0.1 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCL98121.1 - 3.3e-14 52.7 0.0 5.4e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CCL98121.1 - 7.6e-07 28.4 0.0 3.4e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CCL98121.1 - 8.8e-07 28.9 0.0 2.7e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 CCL98121.1 - 6.4e-06 25.4 0.5 0.00062 18.9 0.2 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase YhjQ PF06564.7 CCL98121.1 - 0.044 13.1 0.0 0.075 12.3 0.0 1.4 1 1 0 1 1 1 0 YhjQ protein AAA_26 PF13500.1 CCL98121.1 - 0.054 13.0 0.1 7.8 6.0 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CCL98121.1 - 0.055 13.6 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 CCL98124.1 - 1.2e-18 66.4 0.0 3.7e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL98124.1 - 1.5e-14 53.6 0.0 3e-08 33.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL98124.1 - 1.9e-12 46.8 0.0 2.3e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb6 PF01192.17 CCL98125.1 - 1.4e-21 75.9 0.1 2.1e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 SIR2 PF02146.12 CCL98126.1 - 1.8e-33 115.7 0.0 6.9e-22 78.0 0.0 2.2 2 0 0 2 2 2 2 Sir2 family Transposase_22 PF02994.9 CCL98126.1 - 0.052 12.0 0.0 0.082 11.3 0.0 1.2 1 0 0 1 1 1 0 L1 transposable element DUF4023 PF13215.1 CCL98126.1 - 0.13 12.0 0.2 0.69 9.7 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) EF_TS PF00889.14 CCL98127.1 - 8.2e-19 67.8 0.0 1.9e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor TS Remorin_N PF03766.8 CCL98127.1 - 0.12 12.1 0.3 0.31 10.8 0.2 1.6 1 0 0 1 1 1 0 Remorin, N-terminal region Gar1 PF04410.9 CCL98128.1 - 3.9e-30 104.3 0.1 3.9e-30 104.3 0.0 2.3 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region CAML PF14963.1 CCL98128.1 - 8.8 5.6 8.1 6 6.1 0.1 2.2 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand PEHE PF15275.1 CCL98129.1 - 2.3e-05 24.8 0.4 2.3e-05 24.8 0.3 2.9 3 0 0 3 3 3 1 PEHE domain SAS4 PF15460.1 CCL98129.1 - 7.8e-05 22.4 4.3 0.00021 21.1 3.0 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 eIF-3_zeta PF05091.7 CCL98130.1 - 0.39 9.2 6.1 0.5 8.9 4.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Bromodomain PF00439.20 CCL98132.1 - 7.7e-38 128.2 3.7 1e-18 67.0 0.2 2.7 3 0 0 3 3 3 2 Bromodomain Usp PF00582.21 CCL98132.1 - 0.018 15.2 0.8 0.018 15.2 0.6 1.9 2 0 0 2 2 2 0 Universal stress protein family DUF2890 PF11081.3 CCL98132.1 - 0.43 10.6 11.1 0.21 11.6 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) PBP_sp32 PF07222.7 CCL98132.1 - 2.7 7.1 9.5 4.7 6.3 6.4 1.6 1 1 0 1 1 1 0 Proacrosin binding protein sp32 Nucleoplasmin PF03066.10 CCL98132.1 - 3.8 7.0 10.6 0.32 10.5 3.8 1.8 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 CCL98132.1 - 6.5 4.6 9.2 11 3.9 6.4 1.3 1 0 0 1 1 1 0 CDC45-like protein BTB PF00651.26 CCL98133.1 - 0.054 13.4 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Cyt-b5 PF00173.23 CCL98134.1 - 1.2e-07 31.4 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 CCL98134.1 - 0.00011 21.7 23.9 0.00026 20.5 14.7 2.6 1 1 0 1 1 1 1 Fatty acid desaturase CutC PF03932.9 CCL98135.1 - 1.3e-50 171.4 0.1 9.1e-49 165.4 0.0 2.1 1 1 0 1 1 1 1 CutC family PLD_C PF12357.3 CCL98135.1 - 0.038 13.5 0.2 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 Phospholipase D C terminal RabGAP-TBC PF00566.13 CCL98138.1 - 4.9e-47 160.1 0.0 6.5e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HA2 PF04408.18 CCL98140.1 - 5.6e-21 74.4 0.0 1.6e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCL98140.1 - 6.1e-15 55.0 0.0 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCL98140.1 - 5.4e-10 38.9 0.1 1.8e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCL98140.1 - 3.6e-09 36.3 0.4 2.5e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCL98140.1 - 0.00077 19.6 0.3 0.0049 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCL98140.1 - 0.032 13.3 0.0 2 7.4 0.0 2.5 1 1 0 2 2 2 0 Zeta toxin T2SE PF00437.15 CCL98140.1 - 0.077 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein HA2 PF04408.18 CCL98141.1 - 8.1e-30 102.8 0.3 2.5e-29 101.2 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCL98141.1 - 9.8e-30 102.7 0.0 2.2e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCL98141.1 - 7.6e-13 48.1 0.0 2.2e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 CCL98141.1 - 1.2e-06 28.5 0.2 2.5e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 CCL98141.1 - 2.7e-05 23.7 0.0 6.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CCL98141.1 - 0.00014 20.8 0.0 0.00038 19.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CCL98141.1 - 0.0005 20.2 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCL98141.1 - 0.0014 18.2 0.0 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCL98141.1 - 0.009 15.7 0.1 0.029 14.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CCL98141.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCL98141.1 - 0.041 14.1 0.5 1.1 9.5 0.1 3.2 2 1 1 3 3 3 0 ABC transporter ResIII PF04851.10 CCL98141.1 - 0.094 12.5 0.1 5.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NTF2 PF02136.15 CCL98142.1 - 3.6e-11 43.4 0.0 6.1e-10 39.4 0.0 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 CCL98142.1 - 0.00084 19.1 0.0 0.00097 18.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 2OG-FeII_Oxy PF03171.15 CCL98143.1 - 2.5e-15 56.5 0.0 6.3e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CCL98143.1 - 6.6e-12 45.9 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Adaptin_N PF01602.15 CCL98144.1 - 5e-105 351.7 0.0 7e-105 351.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCL98144.1 - 8.3e-11 42.0 2.8 0.0052 17.0 0.9 5.6 3 3 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 CCL98144.1 - 2.5e-06 27.4 0.8 0.019 14.8 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCL98144.1 - 2.7e-06 26.9 2.2 12 6.3 0.0 6.4 5 1 1 6 6 6 1 HEAT repeat RasGEF_N_2 PF14663.1 CCL98144.1 - 0.0027 17.6 0.7 0.89 9.5 0.0 3.4 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2435 PF10363.4 CCL98144.1 - 0.0043 16.9 4.2 0.16 11.8 0.5 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Proteasom_PSMB PF10508.4 CCL98144.1 - 0.0049 15.2 0.4 0.35 9.1 0.1 2.6 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 CCL98144.1 - 0.04 14.4 4.4 43 4.7 0.0 6.2 7 0 0 7 7 7 0 HEAT-like repeat Pkinase PF00069.20 CCL98145.1 - 4.4e-71 239.0 0.0 6.7e-71 238.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98145.1 - 2.2e-51 174.4 0.0 3.3e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCL98145.1 - 3.1e-05 23.0 0.0 0.00041 19.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 CCL98145.1 - 0.0031 16.7 0.6 0.0046 16.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) UQ_con PF00179.21 CCL98146.1 - 2.6e-10 39.8 0.0 1.3e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Cation_efflux PF01545.16 CCL98147.1 - 2.5e-30 105.5 5.2 3e-30 105.2 3.6 1.1 1 0 0 1 1 1 1 Cation efflux family ADH_zinc_N PF00107.21 CCL98150.1 - 2.5e-27 94.9 0.0 4.7e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCL98150.1 - 2.1e-13 51.2 0.0 5.9e-13 49.8 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCL98150.1 - 5.1e-09 35.8 0.0 1.6e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PA PF02225.17 CCL98150.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 PA domain ING PF12998.2 CCL98153.1 - 1.2e-09 38.3 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCL98153.1 - 4e-09 36.0 5.6 6.4e-09 35.3 3.9 1.3 1 0 0 1 1 1 1 PHD-finger Exo5 PF09810.4 CCL98155.1 - 1e-61 208.9 0.0 4.5e-51 174.0 0.0 3.0 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 CCL98155.1 - 0.0044 16.4 0.0 0.046 13.1 0.0 2.4 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Pkinase PF00069.20 CCL98156.1 - 1.1e-37 129.6 0.0 1.7e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98156.1 - 6e-29 100.8 0.0 8.7e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCL98156.1 - 0.096 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Sec20 PF03908.8 CCL98156.1 - 0.24 11.1 0.0 0.59 9.8 0.0 1.6 1 0 0 1 1 1 0 Sec20 NAD_binding_2 PF03446.10 CCL98158.1 - 2e-24 86.3 0.1 3.4e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CCL98158.1 - 9.1e-10 38.6 0.1 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CCL98158.1 - 3.7e-07 30.4 0.1 7.6e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 CCL98158.1 - 1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 CCL98158.1 - 0.028 13.2 0.1 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.14 CCL98158.1 - 0.051 12.7 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WSS_VP PF12175.3 CCL98158.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP dsrm PF00035.20 CCL98160.1 - 6.7e-11 42.6 0.0 7.6e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Sec3-PIP2_bind PF15277.1 CCL98161.1 - 7.4e-20 70.6 0.0 1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Fip1 PF05182.8 CCL98162.1 - 4.8e-20 70.5 0.2 7.4e-20 69.9 0.1 1.3 1 0 0 1 1 1 1 Fip1 motif Prp19_bind PF06991.6 CCL98162.1 - 3.8 6.7 6.7 5.4 6.2 4.7 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain HEAT_2 PF13646.1 CCL98163.1 - 1.4e-05 25.2 0.4 0.0023 18.1 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.18 CCL98163.1 - 0.0018 18.0 0.0 0.0018 18.0 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CCL98163.1 - 0.0029 17.5 2.9 20 5.5 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 CCL98163.1 - 0.0031 17.9 0.5 1.3 9.6 0.0 4.1 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.15 CCL98163.1 - 0.0075 14.6 0.8 0.018 13.4 0.1 1.7 2 0 0 2 2 2 1 Adaptin N terminal region RIX1 PF08167.7 CCL98163.1 - 0.013 15.1 1.8 0.18 11.5 0.0 3.2 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Fasciclin PF02469.17 CCL98164.1 - 1.1e-06 28.6 0.0 9.2e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Fasciclin domain Vps39_1 PF10366.4 CCL98167.1 - 4.4e-26 91.0 0.0 1.6e-25 89.2 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Ank_2 PF12796.2 CCL98167.1 - 2e-25 88.9 4.7 1.9e-12 47.3 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCL98167.1 - 4e-23 81.3 10.1 2.3e-05 24.7 0.0 6.9 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Vps39_2 PF10367.4 CCL98167.1 - 1.5e-22 79.8 0.2 3.9e-22 78.4 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Ank PF00023.25 CCL98167.1 - 1.3e-17 62.5 10.9 6.6e-06 25.6 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 CCL98167.1 - 1.1e-16 60.3 14.8 8.6e-05 22.6 0.0 6.1 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCL98167.1 - 1.6e-11 43.2 10.4 0.0016 18.4 0.0 7.3 7 0 0 7 7 6 2 Ankyrin repeat CNH PF00780.17 CCL98167.1 - 2.1e-11 43.7 0.0 4.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 CCL98167.1 - 0.0032 17.0 0.2 0.66 9.5 0.0 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.23 CCL98167.1 - 0.09 12.4 1.0 12 5.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 CCL98167.1 - 0.13 12.7 8.2 43 4.9 0.6 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCL98167.1 - 4 7.5 7.4 35 4.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TAP_C PF03943.8 CCL98168.1 - 2.1e-08 33.4 0.0 5.5e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 CCL98168.1 - 2.8e-06 27.6 0.1 8.2e-05 22.9 0.1 2.6 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.2 CCL98168.1 - 0.00012 21.6 4.6 0.013 15.0 0.5 3.4 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) UBA_4 PF14555.1 CCL98168.1 - 0.0015 18.0 0.1 0.0044 16.5 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain SnoaL_4 PF13577.1 CCL98168.1 - 0.031 14.1 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain PIG-H PF10181.4 CCL98168.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component DUF2146 PF10220.4 CCL98169.1 - 5.3 4.8 5.5 7.5 4.3 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) LysM PF01476.15 CCL98172.1 - 0.016 15.1 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 LysM domain Exo_endo_phos PF03372.18 CCL98173.1 - 1.7e-12 47.8 0.5 2.9e-12 47.0 0.4 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GFA PF04828.9 CCL98173.1 - 2.6e-11 43.3 0.9 5.2e-11 42.3 0.6 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.11 CCL98174.1 - 6.6e-21 74.4 57.4 4.4e-17 61.8 29.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily APG17 PF04108.7 CCL98175.1 - 4.9e-30 104.6 20.2 8.3e-27 94.0 10.3 3.0 2 1 0 2 2 2 2 Autophagy protein Apg17 Herpes_UL36 PF03586.8 CCL98175.1 - 0.17 10.9 6.7 0.02 13.9 0.9 2.2 3 0 0 3 3 3 0 Herpesvirus UL36 tegument protein ArsC PF03960.10 CCL98175.1 - 0.24 11.5 2.1 0.58 10.2 0.6 2.2 2 0 0 2 2 2 0 ArsC family DUF745 PF05335.8 CCL98175.1 - 0.38 10.2 8.6 0.04 13.4 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Nsp1_C PF05064.8 CCL98175.1 - 1.1 8.9 7.2 18 5.0 1.4 3.6 3 1 0 3 3 3 0 Nsp1-like C-terminal region Sin3_corepress PF08295.7 CCL98175.1 - 1.2 8.9 4.6 1.2 8.9 0.0 3.1 4 0 0 4 4 4 0 Sin3 family co-repressor DUF2664 PF10867.3 CCL98175.1 - 1.5 9.5 7.8 4.9 7.8 0.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) MutS_III PF05192.13 CCL98175.1 - 2.9 7.6 7.3 37 3.9 4.8 2.6 1 1 0 1 1 1 0 MutS domain III Syntaxin-6_N PF09177.6 CCL98175.1 - 3.8 7.9 11.1 2.5 8.5 0.7 4.2 3 1 1 4 4 4 0 Syntaxin 6, N-terminal MBOAT_2 PF13813.1 CCL98176.1 - 8.2e-19 67.4 4.2 2.3e-18 66.0 2.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Actin PF00022.14 CCL98177.1 - 7.8e-89 297.8 0.0 1.1e-88 297.4 0.0 1.0 1 0 0 1 1 1 1 Actin UPF0061 PF02696.9 CCL98178.1 - 2.4e-85 286.6 0.0 2.9e-61 207.2 0.0 3.6 2 2 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family Acyl-CoA_dh_1 PF00441.19 CCL98179.1 - 9.7e-31 106.9 0.8 1.5e-30 106.3 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCL98179.1 - 6.6e-21 73.5 0.5 4.2e-20 70.9 0.6 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 CCL98179.1 - 1e-15 57.2 0.1 2.7e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 CCL98179.1 - 2.4e-11 44.1 0.0 5.4e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCL98179.1 - 1.4e-05 25.3 0.2 3.2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pro_CA PF00484.14 CCL98180.1 - 2.8e-42 144.3 0.7 3.5e-42 143.9 0.5 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_6 PF12697.2 CCL98180.1 - 0.028 14.3 1.6 0.15 11.9 1.2 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98180.1 - 0.048 13.2 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Asp PF00026.18 CCL98181.1 - 8.2e-31 107.4 4.3 2e-29 102.8 3.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCL98181.1 - 4.7e-07 30.2 2.5 7.2e-06 26.4 1.0 2.5 2 0 0 2 2 2 1 Aspartyl protease TMEM154 PF15102.1 CCL98181.1 - 0.012 15.3 0.1 0.012 15.3 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family RVP PF00077.15 CCL98181.1 - 0.023 14.6 0.4 0.61 10.0 0.1 2.6 2 1 0 2 2 2 0 Retroviral aspartyl protease Carn_acyltransf PF00755.15 CCL98183.1 - 4.1e-163 543.6 0.0 7.5e-163 542.7 0.0 1.4 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Taeniidae_ag PF05596.6 CCL98183.1 - 0.044 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Taeniidae antigen IBR PF01485.16 CCL98184.1 - 1.6e-10 40.6 15.0 3.3e-10 39.6 10.4 1.5 1 0 0 1 1 1 1 IBR domain Metal_resist PF13801.1 CCL98184.1 - 0.049 13.6 0.3 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal resistance DUF1488 PF07369.6 CCL98184.1 - 0.068 13.0 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) zf-C3HC4_3 PF13920.1 CCL98184.1 - 2.6 7.7 12.6 3.8 7.2 3.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCL98184.1 - 3.1 7.7 10.9 6.3 6.7 7.5 1.5 1 0 0 1 1 1 0 Ring finger domain tRNA-synt_2 PF00152.15 CCL98185.1 - 3.4e-90 302.2 0.0 4.6e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCL98185.1 - 1.3e-09 37.7 0.0 3.7e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCL98185.1 - 8.2e-09 35.0 0.0 4.9e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CCL98185.1 - 0.0023 17.5 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_tranf_2_3 PF13641.1 CCL98186.1 - 5.4e-25 88.5 0.0 7.6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CCL98186.1 - 4.9e-10 39.3 0.0 7.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCL98186.1 - 2.4e-08 33.4 0.0 7.3e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 CCL98186.1 - 1.4e-05 24.9 6.5 2.6e-05 24.0 4.4 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 HSP70 PF00012.15 CCL98188.1 - 9e-159 529.1 0.6 9e-159 529.1 0.4 1.5 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CCL98188.1 - 1.3e-09 37.1 0.9 1e-08 34.1 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CCL98188.1 - 0.033 14.0 0.7 0.87 9.4 0.1 3.3 2 1 0 2 2 2 0 Cell division protein FtsA GATase_5 PF13507.1 CCL98189.1 - 4.2e-99 330.6 0.0 6.2e-99 330.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CCL98189.1 - 7.4e-45 152.6 1.0 4.4e-25 88.4 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CCL98189.1 - 6.2e-24 84.0 0.0 2.6e-23 82.0 0.0 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Use1 PF09753.4 CCL98191.1 - 5.9e-14 52.1 0.1 1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 ABC_membrane_3 PF13748.1 CCL98191.1 - 0.11 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Ded_cyto PF06920.8 CCL98191.1 - 0.3 10.3 1.9 0.56 9.4 1.3 1.4 1 0 0 1 1 1 0 Dedicator of cytokinesis MCPVI PF02993.9 CCL98191.1 - 2.3 8.2 5.7 6.8 6.7 0.2 2.2 1 1 0 2 2 2 0 Minor capsid protein VI R3H PF01424.17 CCL98192.1 - 1.8e-12 46.7 0.0 6.8e-12 44.9 0.0 2.1 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 CCL98192.1 - 6.7e-07 28.9 0.5 2.7e-06 27.0 0.3 2.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CCL98192.1 - 0.00064 19.5 0.8 0.00064 19.5 0.6 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site Glyco_hydro_2 PF00703.16 CCL98193.1 - 0.029 14.8 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 AA_permease PF00324.16 CCL98194.1 - 9.4e-117 390.2 36.0 2.1e-85 286.8 11.2 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 CCL98194.1 - 5.4e-37 127.3 40.0 7.8e-35 120.2 27.7 2.0 1 1 0 1 1 1 1 Amino acid permease Consortin_C PF15281.1 CCL98194.1 - 0.39 10.2 2.1 39 3.7 0.0 3.0 3 0 0 3 3 3 0 Consortin C-terminus Glyco_hydro_28 PF00295.12 CCL98195.1 - 1.5e-21 76.7 0.0 2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 PQQ_2 PF13360.1 CCL98195.1 - 0.0015 18.0 0.1 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain Methyltransf_22 PF13383.1 CCL98198.1 - 5.6e-27 94.8 0.0 1.6e-25 90.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 CCL98198.1 - 1.6e-05 24.8 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Pkinase PF00069.20 CCL98200.1 - 2.2e-67 226.9 0.0 2.9e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98200.1 - 2e-38 131.9 0.0 3.1e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCL98200.1 - 2e-16 59.8 0.2 3.7e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 CCL98200.1 - 2.1e-05 23.6 0.0 5.8e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCL98200.1 - 9.2e-05 21.5 0.0 0.0014 17.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pox_Ag35 PF03286.9 CCL98200.1 - 0.28 10.6 3.7 0.57 9.6 2.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein But2 PF09792.4 CCL98203.1 - 4.4e-09 36.2 0.0 7.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Phage_holin PF04688.8 CCL98205.1 - 1.2 8.6 5.1 4 7.0 3.5 1.9 1 1 0 1 1 1 0 Phage lysis protein, holin Vps16_C PF04840.7 CCL98206.1 - 4.1e-83 278.9 0.2 5.6e-83 278.5 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 CCL98206.1 - 1.2e-80 271.1 0.0 1.8e-80 270.4 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region DUF2076 PF09849.4 CCL98208.1 - 8.2e-05 22.7 10.3 0.00011 22.4 7.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CCL98208.1 - 0.0057 16.5 1.6 0.011 15.6 1.1 1.5 1 1 0 1 1 1 1 CHCH domain zinc-ribbons_6 PF07191.7 CCL98208.1 - 0.27 11.0 3.6 0.44 10.3 2.5 1.3 1 0 0 1 1 1 0 zinc-ribbons DUF605 PF04652.11 CCL98208.1 - 5.8 6.2 10.2 6.6 6.0 7.1 1.1 1 0 0 1 1 1 0 Vta1 like TPR_12 PF13424.1 CCL98209.1 - 9.1e-09 35.1 0.8 0.0084 16.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCL98209.1 - 3.4e-07 29.7 0.2 0.091 12.4 0.0 3.9 2 1 1 3 3 3 3 TPR repeat MBA1 PF07961.6 CCL98209.1 - 1.1e-06 27.6 0.0 1.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein TPR_2 PF07719.12 CCL98209.1 - 1.2e-06 27.9 4.3 0.044 13.6 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCL98209.1 - 2.5e-05 23.7 0.0 0.25 11.2 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCL98209.1 - 0.00019 20.8 3.0 0.41 10.3 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCL98209.1 - 0.00021 21.6 9.4 8.6 7.3 0.1 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCL98209.1 - 0.00076 19.0 0.6 1.3 8.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Tim44 PF04280.10 CCL98209.1 - 0.00078 19.4 0.0 0.0024 17.8 0.0 1.8 1 1 0 1 1 1 1 Tim44-like domain MIT PF04212.13 CCL98209.1 - 0.0077 16.0 0.2 7 6.6 0.0 3.6 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 CCL98209.1 - 0.0089 16.6 4.8 8 7.2 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Sec62 PF03839.11 CCL98210.1 - 7.9e-45 153.0 2.8 4.4e-44 150.5 1.8 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 Formyl_trans_N PF00551.14 CCL98212.1 - 1.2e-23 83.5 0.0 2.2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CCL98212.1 - 1.7e-12 47.2 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DEAD PF00270.24 CCL98213.1 - 5.4e-41 139.8 0.4 1.3e-40 138.6 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCL98213.1 - 9.1e-24 83.1 0.1 2e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA PF00004.24 CCL98213.1 - 0.012 15.8 0.0 1.2 9.3 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CMS1 PF14617.1 CCL98213.1 - 0.02 13.9 0.2 0.045 12.8 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Gly_transf_sug PF04488.10 CCL98214.1 - 2.8e-06 27.6 0.0 4.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CCL98214.1 - 0.023 13.8 0.4 0.037 13.1 0.3 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Sdh5 PF03937.11 CCL98215.1 - 8.7e-25 86.2 2.2 1.4e-24 85.5 1.5 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF1759 PF03564.10 CCL98215.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Lentiviral_Tat PF02998.9 CCL98215.1 - 0.56 10.0 3.1 0.51 10.1 1.2 1.6 2 0 0 2 2 2 0 Lentiviral Tat protein Metallophos PF00149.23 CCL98216.1 - 1.3e-44 152.0 0.1 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PH_9 PF15410.1 CCL98217.1 - 7.5e-09 35.7 0.0 5.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.24 CCL98217.1 - 0.0081 16.3 0.0 0.09 12.9 0.0 2.5 3 0 0 3 3 3 1 PH domain Abhydrolase_3 PF07859.8 CCL98218.1 - 1.2e-27 96.8 0.0 2.4e-22 79.5 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CCL98218.1 - 2.9e-05 22.9 0.0 0.00013 20.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) LCAT PF02450.10 CCL98218.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1289 PF06945.8 CCL98219.1 - 0.046 13.1 0.4 0.097 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF1769 PF08588.5 CCL98221.1 - 1.1e-14 54.0 0.0 2.6e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Autophagy_Cterm PF10381.4 CCL98221.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal DFP PF04127.10 CCL98223.1 - 8.7e-22 77.6 0.0 2.9e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Abhydrolase_6 PF12697.2 CCL98224.1 - 3.1e-29 102.4 2.4 1.4e-28 100.3 1.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98224.1 - 7.2e-14 51.8 0.1 5.7e-13 48.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL98224.1 - 9.9e-14 51.3 0.0 9.3e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCL98224.1 - 5.8e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 CCL98224.1 - 0.018 13.9 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 CCL98224.1 - 0.048 12.4 0.9 0.072 11.8 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase Dioxygenase_C PF00775.16 CCL98225.1 - 1.3e-56 190.8 0.0 2.2e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 CCL98225.1 - 1.4e-17 63.4 0.0 4.9e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 CCL98225.1 - 0.0095 15.9 0.2 0.046 13.7 0.2 2.1 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain XPG_I PF00867.13 CCL98226.1 - 4.3e-26 90.7 0.0 9.4e-26 89.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCL98226.1 - 1.8e-07 31.3 0.0 3.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 CCL98226.1 - 5e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 CCL98226.1 - 5.9e-05 22.6 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.12 CCL98226.1 - 0.0049 16.6 0.1 0.016 15.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCL98226.1 - 0.014 15.0 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat HHH_5 PF14520.1 CCL98226.1 - 0.065 13.4 0.1 0.47 10.6 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix domain HHH_2 PF12826.2 CCL98226.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif TPR_4 PF07721.9 CCL98226.1 - 2.2 8.9 5.1 5.3 7.7 1.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 CCL98227.1 - 6.9e-10 38.6 7.2 0.00021 21.4 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCL98227.1 - 1.6e-07 31.1 5.5 0.0011 19.1 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCL98227.1 - 1.9e-06 27.8 8.0 0.00025 21.1 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 CCL98227.1 - 0.032 14.4 2.8 0.043 14.0 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PRP21_like_P PF12230.3 CCL98227.1 - 0.054 12.9 0.1 0.083 12.3 0.1 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_jaz PF12171.3 CCL98227.1 - 0.054 13.6 0.6 0.45 10.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCL98227.1 - 0.071 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger PIG-P PF08510.7 CCL98228.1 - 4.4e-32 110.3 0.9 5.3e-32 110.0 0.6 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 CCL98228.1 - 0.22 11.7 6.4 0.52 10.6 4.4 1.6 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) 5-FTHF_cyc-lig PF01812.15 CCL98229.1 - 3.5e-38 131.2 0.0 4e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family AAA_25 PF13481.1 CCL98230.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad51 PF08423.6 CCL98230.1 - 5.9e-05 22.1 0.0 8.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 DnaB_C PF03796.10 CCL98230.1 - 9.4e-05 21.4 0.0 0.00013 20.9 0.0 1.3 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain KaiC PF06745.8 CCL98230.1 - 0.0027 16.8 0.4 0.015 14.4 0.3 2.0 1 1 0 1 1 1 1 KaiC IstB_IS21 PF01695.12 CCL98230.1 - 0.0056 16.1 0.1 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_31 PF13614.1 CCL98230.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCL98230.1 - 0.0088 16.3 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 CCL98230.1 - 0.018 14.7 0.0 0.038 13.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CCL98230.1 - 0.081 11.6 0.0 0.16 10.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus RRM_1 PF00076.17 CCL98231.1 - 1.1e-26 92.2 0.0 2.2e-11 43.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL98231.1 - 9.4e-17 60.7 0.0 1.1e-07 31.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL98231.1 - 3e-16 59.0 0.0 1.7e-06 27.7 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad9_Rad53_bind PF08605.5 CCL98231.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding HNH_2 PF13391.1 CCL98232.1 - 1.5e-11 43.8 0.1 5.4e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease HEAT PF02985.17 CCL98233.1 - 0.0056 16.6 0.5 0.31 11.2 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CCL98233.1 - 0.0066 16.7 0.3 0.35 11.1 0.0 3.1 2 1 1 3 3 3 1 HEAT repeats Glyco_hydro_16 PF00722.16 CCL98234.1 - 2.6e-39 134.4 5.8 3.8e-39 133.8 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 CCL98234.1 - 0.00056 19.8 13.8 0.0014 18.5 9.6 1.7 1 0 0 1 1 1 1 Chitin recognition protein MutS_V PF00488.16 CCL98235.1 - 6.2e-77 258.1 0.0 9.9e-77 257.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCL98235.1 - 1.6e-41 142.3 0.4 2.8e-41 141.5 0.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCL98235.1 - 2.4e-20 72.6 0.6 1e-19 70.6 0.4 2.2 1 1 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CCL98235.1 - 1.2e-09 38.3 0.0 3.5e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CCL98235.1 - 0.00042 20.4 0.0 0.00097 19.2 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV NMO PF03060.10 CCL98236.1 - 6.2e-29 101.1 0.0 7e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCL98236.1 - 5.6e-06 25.4 2.0 7.1e-06 25.1 1.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CCL98236.1 - 0.0013 17.6 0.5 0.0021 16.9 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CCL98236.1 - 0.016 14.4 0.2 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.12 CCL98236.1 - 0.045 12.6 0.1 0.06 12.2 0.1 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.6 CCL98236.1 - 0.048 13.2 0.1 0.71 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) DHO_dh PF01180.16 CCL98236.1 - 0.087 11.7 0.2 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DnaJ PF00226.26 CCL98237.1 - 8.2e-21 73.5 0.0 2.4e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain MAP7 PF05672.6 CCL98237.1 - 1.6 8.1 31.6 0.21 10.9 16.1 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Mcp5_PH PF12814.2 CCL98238.1 - 3.6e-41 139.9 0.0 7.3e-41 138.9 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Reo_sigmaC PF04582.7 CCL98238.1 - 4 6.5 9.3 0.92 8.6 2.1 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 CCL98238.1 - 4.5 6.8 47.4 0.85 9.1 0.4 4.2 3 1 1 4 4 4 0 IncA protein DSPc PF00782.15 CCL98239.1 - 1.5e-10 40.7 0.0 1.8e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PHD PF00628.24 CCL98240.1 - 1.2e-09 37.6 7.7 1.8e-09 37.1 5.3 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CCL98240.1 - 0.00092 19.3 0.4 0.0012 18.8 0.3 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-C4_Topoisom PF01396.14 CCL98240.1 - 0.014 14.8 2.5 0.21 11.1 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger FANCL_C PF11793.3 CCL98240.1 - 0.017 15.0 1.3 0.031 14.2 0.9 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 CCL98240.1 - 0.085 12.8 0.5 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain ING PF12998.2 CCL98241.1 - 8.2e-09 35.6 0.3 0.00026 21.2 0.1 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding DUF3166 PF11365.3 CCL98241.1 - 0.022 15.2 0.3 0.21 12.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) ATG16 PF08614.6 CCL98241.1 - 0.048 13.4 0.3 0.085 12.6 0.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TRP PF06011.7 CCL98242.1 - 1.6e-45 155.4 35.3 5.6e-45 153.7 24.5 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCL98242.1 - 6.6e-06 26.2 0.8 1e-05 25.5 0.5 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CCL98242.1 - 0.00018 21.7 0.0 0.00029 21.0 0.0 1.3 1 0 0 1 1 1 1 ML domain CNH PF00780.17 CCL98243.1 - 3e-06 26.8 0.0 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 2 CNH domain Mucin PF01456.12 CCL98244.1 - 0.24 11.1 6.5 0.47 10.2 4.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ADH_zinc_N PF00107.21 CCL98245.1 - 5.9e-16 58.1 0.0 9e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCL98245.1 - 3.2e-05 23.6 0.3 0.00024 20.8 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CCL98245.1 - 0.0026 18.6 0.0 0.0049 17.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Plant_vir_prot PF01307.12 CCL98245.1 - 0.02 14.5 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Plant viral movement protein DUF3131 PF11329.3 CCL98245.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) Nop14 PF04147.7 CCL98246.1 - 8e-251 834.5 17.7 1e-250 834.2 12.3 1.0 1 0 0 1 1 1 1 Nop14-like family PI3_PI4_kinase PF00454.22 CCL98247.1 - 8e-50 169.4 0.1 1.6e-49 168.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CCL98247.1 - 5.1e-25 88.2 0.0 1.1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.8 CCL98247.1 - 2.1e-19 69.4 0.0 1.6e-18 66.5 0.0 2.7 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 CCL98247.1 - 6.8e-12 44.6 0.0 1.9e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 FATC domain YEATS PF03366.11 CCL98248.1 - 6.9e-33 112.2 0.1 1.2e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 YEATS family COX7a PF02238.10 CCL98249.1 - 0.0046 16.6 0.1 0.0085 15.7 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIa LANC_like PF05147.8 CCL98249.1 - 0.049 12.2 0.0 0.049 12.2 0.0 1.0 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Coiled-coil_56 PF09813.4 CCL98250.1 - 1.5e-05 24.8 0.0 3e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 Ribonucleas_3_3 PF14622.1 CCL98251.1 - 1.2e-15 57.6 0.0 1.8e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CCL98251.1 - 2.2e-11 44.2 0.0 4.9e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 CCL98251.1 - 4.4e-08 33.5 0.0 7.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif PAPS_reduct PF01507.14 CCL98252.1 - 1.1e-40 139.2 0.0 1.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Aldedh PF00171.17 CCL98253.1 - 1.6e-149 498.1 0.8 2.2e-149 497.7 0.6 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Phage_NinH PF06322.6 CCL98253.1 - 0.023 14.3 0.2 2.2 7.9 0.2 2.5 2 0 0 2 2 2 0 Phage NinH protein Phage_RpbA PF10789.4 CCL98253.1 - 0.15 11.8 0.0 0.5 10.2 0.0 1.8 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA UPF0029 PF01205.14 CCL98254.1 - 3.1e-29 100.8 0.0 4.9e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CCL98254.1 - 7.4e-08 32.2 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 RWD domain ubiquitin PF00240.18 CCL98256.1 - 4.1e-06 26.1 0.0 6.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CCL98256.1 - 1.2e-05 24.9 0.3 1.2e-05 24.9 0.2 3.0 4 0 0 4 4 4 1 UBA/TS-N domain Asp_protease PF09668.5 CCL98256.1 - 2.4e-05 23.8 0.9 0.001 18.6 0.1 2.3 1 1 1 2 2 2 2 Aspartyl protease UBA_4 PF14555.1 CCL98256.1 - 9.7e-05 21.8 0.0 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain XPC-binding PF09280.6 CCL98256.1 - 0.0048 16.3 0.1 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 XPC-binding domain RuvA_C PF07499.8 CCL98256.1 - 0.059 13.5 0.8 0.059 13.5 0.6 2.0 2 0 0 2 2 2 0 RuvA, C-terminal domain TFIID-18kDa PF02269.11 CCL98257.1 - 9.2e-33 111.9 0.4 2.4e-32 110.6 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit FAA_hydrolase PF01557.13 CCL98258.1 - 4.4e-56 189.7 0.0 5.7e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CDC14 PF08045.6 CCL98259.1 - 1.4e-34 119.4 0.0 6.5e-30 104.1 0.0 2.8 2 1 0 2 2 2 2 Cell division control protein 14, SIN component ENTH PF01417.15 CCL98259.1 - 0.092 12.6 0.1 0.75 9.6 0.1 2.2 1 1 1 2 2 2 0 ENTH domain HABP4_PAI-RBP1 PF04774.10 CCL98260.1 - 0.0028 18.1 1.5 0.0043 17.5 1.0 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Arb1 PF09692.5 CCL98262.1 - 8.3e-09 34.7 0.1 1.5e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF4090 PF13319.1 CCL98262.1 - 0.072 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) ATG22 PF11700.3 CCL98264.1 - 8.1e-98 327.9 23.8 9.3e-98 327.7 16.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CCL98264.1 - 1.4e-12 46.9 34.7 3.6e-10 39.0 3.4 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3787 PF12655.2 CCL98264.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) Acetyltransf_7 PF13508.1 CCL98265.1 - 7.7e-12 45.2 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCL98265.1 - 5.8e-07 29.4 0.1 4.8e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCL98265.1 - 0.0001 22.4 0.0 0.00092 19.3 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCL98265.1 - 0.0014 18.4 0.0 0.013 15.3 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCL98265.1 - 0.0062 16.2 0.0 0.36 10.5 0.0 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.1 CCL98265.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.1 CCL98265.1 - 0.034 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 CCL98266.1 - 6.3e-14 51.9 0.0 1.9e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCL98266.1 - 1.4e-08 34.8 0.0 3.3e-07 30.4 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCL98266.1 - 8.4e-07 28.9 0.1 1.7e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.1 CCL98266.1 - 0.0006 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase FR47 PF08445.5 CCL98266.1 - 0.00083 19.0 0.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 CCL98266.1 - 0.0068 16.2 0.0 0.47 10.3 0.1 3.2 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCL98266.1 - 0.072 12.9 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase WD40 PF00400.27 CCL98267.1 - 5e-36 121.2 13.9 9.1e-06 25.3 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat PQQ_2 PF13360.1 CCL98267.1 - 0.0066 15.9 0.5 4.1 6.7 0.0 3.1 2 1 0 2 2 2 2 PQQ-like domain RhoGEF PF00621.15 CCL98268.1 - 1.5e-35 122.7 0.0 3e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Cluap1 PF10234.4 CCL98268.1 - 0.00042 19.6 1.5 0.001 18.3 1.1 1.7 1 0 0 1 1 1 1 Clusterin-associated protein-1 Sec8_exocyst PF04048.9 CCL98268.1 - 0.04 13.5 1.3 0.076 12.6 0.2 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.7 CCL98268.1 - 0.11 12.2 13.2 0.07 12.8 5.0 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Ins_allergen_rp PF06757.8 CCL98268.1 - 0.12 11.8 1.6 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification ADIP PF11559.3 CCL98268.1 - 0.31 10.9 7.4 0.27 11.1 1.0 2.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 CCL98268.1 - 0.42 10.6 6.1 1 9.4 0.5 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Myb_DNA-binding PF00249.26 CCL98269.1 - 0.0011 19.0 1.2 0.016 15.2 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF2146 PF10220.4 CCL98269.1 - 0.89 7.4 8.4 1.3 6.9 5.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Aminotran_1_2 PF00155.16 CCL98270.1 - 1.8e-12 46.9 0.0 1.9e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II PH_3 PF14593.1 CCL98270.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 PH domain zf-CCHC PF00098.18 CCL98271.1 - 1.4e-09 37.4 2.0 1.4e-09 37.4 1.4 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 CCL98271.1 - 0.0038 16.6 0.4 0.0073 15.7 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCL98271.1 - 0.0052 16.4 1.8 0.0068 16.1 1.2 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CCL98271.1 - 0.094 12.3 0.7 0.15 11.7 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Yae1_N PF09811.4 CCL98272.1 - 0.076 12.5 0.6 0.21 11.1 0.4 1.7 1 0 0 1 1 1 0 Essential protein Yae1, N terminal p450 PF00067.17 CCL98273.1 - 6.5e-64 216.1 0.0 1.3e-62 211.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DNA_binding_1 PF01035.15 CCL98273.1 - 0.16 11.7 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Peptidase_S28 PF05577.7 CCL98274.1 - 1.4e-36 126.0 1.0 6.6e-36 123.8 0.7 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CCL98274.1 - 4.6e-05 23.4 0.0 6.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCL98274.1 - 0.0019 17.4 0.0 0.0039 16.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 CCL98275.1 - 0.00035 19.2 0.0 0.00039 19.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 14-3-3 PF00244.15 CCL98276.1 - 5.3e-118 392.2 4.5 6.1e-118 392.0 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein HisKA PF00512.20 CCL98276.1 - 0.039 13.9 0.7 2.3 8.2 0.1 2.8 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF837 PF05769.6 CCL98276.1 - 0.11 11.9 4.8 1 8.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_19 PF14559.1 CCL98276.1 - 0.31 11.4 2.0 2.4 8.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat XkdW PF09636.5 CCL98277.1 - 0.011 15.5 0.2 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 XkdW protein DUF2633 PF11119.3 CCL98277.1 - 0.019 14.6 0.3 0.053 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) eIF3_subunit PF08597.5 CCL98277.1 - 0.041 13.4 1.0 0.039 13.5 0.7 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3618 PF12277.3 CCL98277.1 - 0.17 11.9 3.7 0.38 10.8 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF3481 PF11980.3 CCL98278.1 - 0.63 9.8 0.1 0.63 9.8 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) AMP-binding PF00501.23 CCL98279.1 - 2.4e-59 200.7 0.0 3e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 CCL98280.1 - 1.3e-52 179.0 0.0 2.3e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 CCL98280.1 - 3.2e-52 177.5 0.0 5.5e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CCL98280.1 - 2.7e-32 111.9 0.3 9.8e-29 100.2 0.0 2.5 2 0 0 2 2 2 2 KR domain NAD_binding_4 PF07993.7 CCL98280.1 - 7e-32 110.3 0.0 1.1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCL98280.1 - 2.6e-30 105.5 2.4 9.8e-26 90.6 0.0 3.3 3 0 0 3 3 3 2 short chain dehydrogenase PS-DH PF14765.1 CCL98280.1 - 6.7e-29 100.9 0.0 1.6e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 CCL98280.1 - 1.1e-27 96.1 0.0 3.2e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 CCL98280.1 - 2.1e-11 43.7 0.0 6.1e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CCL98280.1 - 4.1e-05 23.7 0.4 0.00011 22.4 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 CCL98280.1 - 0.0069 16.4 0.4 2.6 8.0 0.0 3.2 3 0 0 3 3 3 1 NADH(P)-binding Thiolase_N PF00108.18 CCL98280.1 - 0.02 13.8 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain RmlD_sub_bind PF04321.12 CCL98280.1 - 0.051 12.4 0.0 4.7 6.0 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CCL98280.1 - 0.051 12.4 0.2 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.8 CCL98280.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family PCRF PF03462.13 CCL98280.1 - 0.48 10.1 0.0 1.2 8.8 0.0 1.6 1 0 0 1 1 1 0 PCRF domain Rhomboid PF01694.17 CCL98281.1 - 5.2e-34 117.3 11.9 1.6e-33 115.8 8.3 1.8 1 0 0 1 1 1 1 Rhomboid family DIL PF01843.14 CCL98281.1 - 4.9e-20 71.3 0.4 9.6e-20 70.4 0.2 1.5 1 0 0 1 1 1 1 DIL domain Ank PF00023.25 CCL98281.1 - 1.8e-06 27.4 0.1 0.0031 17.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CCL98281.1 - 2.1e-05 24.7 0.0 5.8e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCL98281.1 - 0.0017 18.4 1.5 0.037 14.2 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 CCL98281.1 - 0.0025 18.2 0.1 0.15 12.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCL98281.1 - 0.0066 16.6 0.4 0.057 13.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Rrp15p PF07890.7 CCL98282.1 - 1.9e-17 63.5 12.9 3.2e-16 59.5 8.9 2.2 1 1 0 1 1 1 1 Rrp15p SR-25 PF10500.4 CCL98282.1 - 0.0021 17.5 14.4 0.0031 17.0 10.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CLTH PF10607.4 CCL98283.1 - 3.9e-37 127.1 0.3 4.6e-37 126.9 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CCL98283.1 - 6.6e-06 25.6 0.1 1.4e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 LisH Pkinase PF00069.20 CCL98284.1 - 7.1e-69 231.8 0.0 9.8e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98284.1 - 1e-45 155.8 0.0 1.6e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCL98284.1 - 2.4e-09 36.5 0.0 1.5e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCL98284.1 - 0.0029 16.6 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CCL98284.1 - 0.024 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF866 PF05907.8 CCL98285.1 - 1.5e-41 141.5 0.0 1.8e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_Tnp_IS1 PF03811.8 CCL98285.1 - 0.44 10.0 2.3 2.4 7.7 0.1 2.3 2 0 0 2 2 2 0 InsA N-terminal domain MRP-S28 PF10213.4 CCL98286.1 - 4.1e-30 104.4 0.0 7.9e-30 103.5 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Septin PF00735.13 CCL98287.1 - 1.1e-122 408.4 0.0 1.1e-122 408.4 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CCL98287.1 - 2.4e-07 30.6 0.0 5.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCL98287.1 - 1.1e-05 24.9 1.3 0.00049 19.5 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCL98287.1 - 1.3e-05 24.4 0.2 6.3e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CCL98287.1 - 0.00015 22.0 7.0 0.011 16.0 0.4 2.6 2 1 0 2 2 2 2 ABC transporter AAA_22 PF13401.1 CCL98287.1 - 0.001 19.2 0.0 0.0079 16.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 CCL98287.1 - 0.0021 17.4 0.0 0.011 15.1 0.0 2.2 2 1 1 3 3 3 1 Ras family AIG1 PF04548.11 CCL98287.1 - 0.004 16.2 1.3 0.0052 15.9 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 CCL98287.1 - 0.0067 16.9 0.1 0.051 14.0 0.0 2.3 3 0 0 3 3 2 1 Miro-like protein Dynamin_N PF00350.18 CCL98287.1 - 0.0081 15.9 4.4 0.023 14.4 0.1 2.9 2 1 0 2 2 2 1 Dynamin family AAA_29 PF13555.1 CCL98287.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 CCL98287.1 - 0.012 15.2 0.2 3.3 7.1 0.0 3.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CCL98287.1 - 0.013 14.9 0.1 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 CCL98287.1 - 0.033 14.1 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 CCL98287.1 - 0.077 12.7 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Strep_SA_rep PF06696.6 CCL98287.1 - 0.21 11.3 5.4 0.086 12.6 0.9 2.2 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Exonuc_VII_L PF02601.10 CCL98287.1 - 0.45 9.6 5.6 0.95 8.5 3.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 CCL98287.1 - 0.57 9.7 5.0 0.96 9.0 3.5 1.3 1 0 0 1 1 1 0 IncA protein Xpo1 PF08389.7 CCL98288.1 - 8e-23 80.9 0.0 3.2e-21 75.8 0.0 3.4 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 CCL98288.1 - 0.00027 20.7 0.0 0.0045 16.8 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 CCL98288.1 - 0.0051 17.2 0.2 9.5 6.8 0.0 3.8 3 0 0 3 3 3 2 HEAT-like repeat CoA_binding PF02629.14 CCL98289.1 - 3.5e-29 101.1 0.1 7.3e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 CCL98289.1 - 3.7e-24 85.0 0.1 6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Ank_5 PF13857.1 CCL98289.1 - 2.2e-16 59.5 0.8 5.6e-16 58.2 0.6 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCL98289.1 - 2.3e-13 50.2 0.3 9.4e-13 48.3 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCL98289.1 - 2.4e-13 50.2 0.2 3.1e-09 37.0 0.0 2.8 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCL98289.1 - 4.6e-13 48.2 1.0 2.5e-11 42.8 0.0 3.7 5 0 0 5 5 5 1 Ankyrin repeat ACBP PF00887.14 CCL98289.1 - 7.5e-12 44.7 0.0 1.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_3 PF13606.1 CCL98289.1 - 1.4e-10 40.3 0.2 8.9e-08 31.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Succ_CoA_lig PF13607.1 CCL98289.1 - 3.1e-06 26.8 0.0 7.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.17 CCL98289.1 - 0.0048 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.1 CCL98289.1 - 0.013 15.6 0.2 0.053 13.6 0.1 2.1 1 1 1 2 2 2 0 CoA binding domain Ribosomal_S16 PF00886.14 CCL98290.1 - 4.9e-18 64.5 0.0 7e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Arm PF00514.18 CCL98291.1 - 1.2e-90 294.6 10.6 2.2e-12 46.2 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCL98291.1 - 7.8e-23 80.5 0.1 1.3e-08 34.9 0.0 5.5 1 1 5 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 CCL98291.1 - 6.1e-22 77.4 3.2 3.9e-08 33.5 0.0 5.5 5 1 0 5 5 5 3 HEAT-like repeat IBB PF01749.15 CCL98291.1 - 1.2e-19 70.2 3.1 1.8e-19 69.6 2.1 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 CCL98291.1 - 1.2e-17 62.3 0.2 0.00018 21.2 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat LSM PF01423.17 CCL98291.1 - 2e-17 62.5 0.0 3.7e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 LSM domain Adaptin_N PF01602.15 CCL98291.1 - 6.6e-06 24.7 0.0 0.0018 16.7 0.0 3.0 1 1 1 2 2 2 1 Adaptin N terminal region Arm_2 PF04826.8 CCL98291.1 - 2.4e-05 23.6 0.0 0.34 9.9 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like RICTOR_V PF14668.1 CCL98291.1 - 9e-05 22.3 2.0 0.16 11.9 0.0 4.2 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 CCL98291.1 - 0.00044 20.1 0.0 1 9.3 0.0 4.4 3 1 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 CCL98291.1 - 0.0012 19.1 0.8 0.61 10.7 0.0 4.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.6 CCL98291.1 - 0.013 14.5 0.0 0.034 13.1 0.0 1.6 2 0 0 2 2 2 0 Mo25-like Proteasom_PSMB PF10508.4 CCL98291.1 - 0.053 11.7 0.0 0.31 9.2 0.0 2.1 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit PC_rep PF01851.17 CCL98292.1 - 2.3e-33 112.5 28.4 1.2e-08 34.7 0.0 9.1 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CCL98292.1 - 3.8e-20 71.9 0.2 6.6e-11 42.3 0.0 4.2 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 CCL98292.1 - 1.2e-08 34.3 0.3 1.4 9.2 0.1 5.0 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 CCL98292.1 - 2.3e-06 27.9 4.3 0.013 15.9 0.0 5.1 5 0 0 5 5 5 2 HEAT-like repeat NARP1 PF12569.3 CCL98292.1 - 0.33 9.6 3.9 1.1 7.9 2.1 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Apc3 PF12895.2 CCL98292.1 - 0.36 11.0 2.6 0.62 10.2 0.2 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CCL98292.1 - 2.1 8.4 6.2 1.6 8.8 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat COX6A PF02046.10 CCL98293.1 - 3.8e-26 91.2 0.4 4.7e-26 90.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa YiiD_Cterm PF09500.5 CCL98294.1 - 0.09 12.3 3.9 4.6 6.8 0.2 3.1 2 1 1 3 3 3 0 Putative thioesterase (yiiD_Cterm) FAM220 PF15487.1 CCL98294.1 - 0.14 11.5 1.9 0.12 11.6 0.3 1.5 2 0 0 2 2 2 0 FAM220 family Ribul_P_3_epim PF00834.14 CCL98295.1 - 3.1e-32 111.3 0.0 8.4e-27 93.5 0.0 2.0 1 1 1 2 2 2 2 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 CCL98295.1 - 0.05 13.5 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain PK PF00224.16 CCL98296.1 - 6.5e-153 508.4 0.5 8.6e-153 508.0 0.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CCL98296.1 - 1.1e-31 108.8 0.0 2.1e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Gly_transf_sug PF04488.10 CCL98296.1 - 7.6e-05 23.0 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif HpcH_HpaI PF03328.9 CCL98296.1 - 0.00081 18.3 0.2 0.0015 17.5 0.1 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Glyco_transf_41 PF13844.1 CCL98296.1 - 0.17 9.7 0.0 0.27 9.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 LAG1-DNAbind PF09271.6 CCL98297.1 - 1.2e-26 93.8 0.0 4.3e-25 88.8 0.0 2.4 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 CCL98297.1 - 7.6e-25 87.4 0.0 1.8e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF4203 PF13886.1 CCL98299.1 - 3.9e-38 131.0 28.7 5.5e-38 130.5 19.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DEAD PF00270.24 CCL98300.1 - 9.1e-18 64.3 0.0 2.4e-17 62.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCL98300.1 - 8.9e-08 31.8 0.0 5.9e-07 29.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CCL98300.1 - 0.021 13.8 0.0 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Sugar_tr PF00083.19 CCL98301.1 - 9.7e-105 350.7 12.7 1.1e-104 350.5 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCL98301.1 - 1.2e-33 116.3 42.7 1.8e-27 95.9 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCL98301.1 - 1.6e-09 36.6 15.0 3.1e-06 25.8 2.5 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein PPR_2 PF13041.1 CCL98303.1 - 1.6e-45 152.8 0.2 3.9e-07 29.9 0.0 9.9 6 3 4 10 10 10 9 PPR repeat family PPR_3 PF13812.1 CCL98303.1 - 3.8e-26 89.1 16.2 0.0011 19.0 0.0 12.3 13 1 0 13 13 13 5 Pentatricopeptide repeat domain PPR PF01535.15 CCL98303.1 - 9.9e-22 75.3 1.5 0.0029 17.4 0.0 10.0 11 1 0 11 11 11 5 PPR repeat PPR_1 PF12854.2 CCL98303.1 - 1.2e-18 66.2 5.8 0.11 12.0 0.0 10.0 10 0 0 10 10 10 6 PPR repeat RabGAP-TBC PF00566.13 CCL98303.1 - 0.093 12.1 0.2 16 4.8 0.0 2.5 3 0 0 3 3 3 0 Rab-GTPase-TBC domain RPM2 PF08579.6 CCL98303.1 - 0.11 12.6 0.3 8.6 6.5 0.0 3.5 3 1 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) Pro_isomerase PF00160.16 CCL98304.1 - 5.3e-44 150.1 0.0 8e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 CCL98304.1 - 0.0032 16.6 0.0 0.013 14.6 0.0 2.0 2 1 0 2 2 2 1 Rtf2 RING-finger Pyr_redox_3 PF13738.1 CCL98306.1 - 3.5e-16 59.8 0.0 9.2e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCL98306.1 - 6.6e-11 41.1 0.1 1.8e-07 29.7 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 CCL98306.1 - 1.2e-07 31.6 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CCL98306.1 - 4.9e-05 22.3 0.2 0.0084 15.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCL98306.1 - 0.017 15.0 0.0 0.055 13.3 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCL98306.1 - 0.029 14.1 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 CCL98306.1 - 0.05 12.4 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 CCL98306.1 - 0.11 10.9 0.1 0.18 10.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein PARP PF00644.15 CCL98307.1 - 4e-15 55.7 0.2 1.4e-12 47.4 0.2 2.8 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF4470 PF14737.1 CCL98308.1 - 5.1e-23 80.7 0.1 8.7e-23 79.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 CCL98308.1 - 0.00018 21.2 12.7 0.053 13.4 2.7 2.7 2 0 0 2 2 2 2 MYND finger Dabb PF07876.7 CCL98308.1 - 0.13 12.7 0.1 3.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain Imp-YgjV PF10688.4 CCL98310.1 - 0.17 11.2 2.5 0.24 10.8 1.8 1.2 1 0 0 1 1 1 0 Bacterial inner membrane protein DUF4470 PF14737.1 CCL98311.1 - 6.5e-25 86.7 0.1 1.4e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 CCL98311.1 - 5.6e-10 38.9 11.5 1.2e-09 37.8 8.0 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 CCL98311.1 - 0.7 9.5 7.8 1.4 8.6 5.4 1.5 1 0 0 1 1 1 0 HIT zinc finger CotE PF10628.4 CCL98312.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) E1-E2_ATPase PF00122.15 CCL98313.1 - 7.3e-54 182.2 2.8 7.3e-54 182.2 1.9 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCL98313.1 - 1.6e-30 105.9 3.8 1.6e-30 105.9 2.6 3.0 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCL98313.1 - 2.5e-29 103.2 0.0 5e-28 98.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCL98313.1 - 9.8e-18 63.9 0.0 2.6e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCL98313.1 - 2.1e-16 60.6 0.0 8.6e-16 58.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCL98313.1 - 7.8e-11 41.2 0.0 1.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCL98313.1 - 1.3e-07 31.4 0.3 2.7e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.2 CCL98314.1 - 3.1e-08 33.2 0.1 1.1e-07 31.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCL98314.1 - 0.0096 15.5 0.0 0.034 13.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain Reo_sigmaC PF04582.7 CCL98315.1 - 0.0011 18.2 1.7 0.0011 18.2 1.2 4.3 3 1 2 5 5 5 3 Reovirus sigma C capsid protein ADIP PF11559.3 CCL98315.1 - 2 8.2 84.5 0.21 11.4 0.4 6.5 1 1 4 6 6 6 0 Afadin- and alpha -actinin-Binding FBP PF07299.6 CCL98315.1 - 2.8 7.2 4.9 0.53 9.5 0.5 1.9 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) ATG16 PF08614.6 CCL98315.1 - 3.4 7.4 94.2 0.075 12.8 19.7 5.5 2 1 4 6 6 6 0 Autophagy protein 16 (ATG16) Pkinase PF00069.20 CCL98316.1 - 8.9e-10 38.1 0.0 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98316.1 - 4.1e-06 26.0 0.1 2.9e-05 23.2 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.18 CCL98316.1 - 0.0001 22.1 0.2 0.011 15.4 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCL98316.1 - 0.076 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box PF00646.28 CCL98317.1 - 0.0092 15.6 0.4 0.022 14.3 0.3 1.7 1 0 0 1 1 1 1 F-box domain DUF4470 PF14737.1 CCL98318.1 - 1.3e-20 72.9 0.1 2.2e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) DUF4470 PF14737.1 CCL98321.1 - 1.3e-22 79.4 0.0 2.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) MFS_1 PF07690.11 CCL98322.1 - 1.3e-45 155.6 28.7 2.1e-45 155.0 19.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCL98322.1 - 6e-14 51.4 16.6 2.9e-13 49.2 11.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Atg14 PF10186.4 CCL98323.1 - 1.6e-31 109.4 0.0 2.8e-30 105.2 0.0 2.0 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Dynamin_M PF01031.15 CCL98324.1 - 2.2e-30 105.4 0.0 4.2e-19 68.4 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 CCL98324.1 - 1.5e-27 96.5 0.0 3.6e-27 95.2 0.0 1.7 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 CCL98324.1 - 7.6e-08 32.1 0.9 2.3e-07 30.5 0.0 2.3 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCL98324.1 - 1.2e-05 25.2 0.0 0.00012 21.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCL98324.1 - 0.0028 18.1 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 CCL98324.1 - 0.016 14.7 0.0 0.044 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCL98324.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter But2 PF09792.4 CCL98325.1 - 0.00022 21.0 0.1 0.00034 20.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Cys_rich_CPCC PF14206.1 CCL98325.1 - 0.1 12.1 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC RNase_H PF00075.19 CCL98327.1 - 5e-12 46.2 0.0 1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 RNase H MIP PF00230.15 CCL98329.1 - 3.2e-42 144.5 17.6 4.2e-42 144.1 12.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein ATP_synt_H PF05493.8 CCL98329.1 - 0.63 10.1 7.1 1.7 8.7 0.9 2.9 3 0 0 3 3 3 0 ATP synthase subunit H Tmemb_14 PF03647.8 CCL98329.1 - 1.8 9.0 12.2 0.14 12.5 2.2 3.0 2 1 1 3 3 3 0 Transmembrane proteins 14C eIF-5_eIF-2B PF01873.12 CCL98330.1 - 2.5e-42 143.4 0.0 4.1e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CCL98330.1 - 8.8e-28 96.0 2.5 3.3e-26 91.0 0.4 2.6 2 0 0 2 2 2 2 eIF4-gamma/eIF5/eIF2-epsilon DNA_methylase PF00145.12 CCL98331.1 - 3.5e-17 62.5 0.0 4.7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase PHD PF00628.24 CCL98332.1 - 3e-12 46.0 4.7 5.2e-12 45.2 3.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCL98332.1 - 0.08 12.2 2.1 0.14 11.5 1.5 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 CCL98332.1 - 0.33 10.7 5.2 0.2 11.4 2.1 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 GAS PF13851.1 CCL98333.1 - 0.067 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FYVE PF01363.16 CCL98334.1 - 1.3e-18 66.6 5.5 2.4e-18 65.7 3.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger NAD_binding_10 PF13460.1 CCL98335.1 - 0.0092 15.9 0.0 0.026 14.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding p450 PF00067.17 CCL98337.1 - 1.7e-79 267.4 0.0 2.1e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 CCL98337.1 - 0.012 15.2 0.1 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 Reticulon p450 PF00067.17 CCL98338.1 - 1.9e-76 257.4 0.0 2.3e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 CCL98338.1 - 0.08 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Reticulon p450 PF00067.17 CCL98339.1 - 4.5e-15 55.1 0.1 5.8e-15 54.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAM176 PF14851.1 CCL98339.1 - 0.084 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Oxysterol_BP PF01237.13 CCL98340.1 - 2.4e-83 279.5 0.0 3.1e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DUF869 PF05911.6 CCL98342.1 - 3.9e-05 22.1 23.1 3.9e-05 22.1 16.0 2.8 2 1 1 3 3 3 1 Plant protein of unknown function (DUF869) PAM2 PF07145.10 CCL98342.1 - 0.00015 21.0 16.5 0.098 12.1 0.0 4.8 4 0 0 4 4 4 2 Ataxin-2 C-terminal region MscS_porin PF12795.2 CCL98342.1 - 0.00046 19.5 2.1 0.00046 19.5 1.4 3.5 1 1 2 3 3 3 1 Mechanosensitive ion channel porin domain Shugoshin_N PF07558.6 CCL98342.1 - 0.0014 18.2 2.6 1.2 8.8 0.1 2.8 2 0 0 2 2 2 2 Shugoshin N-terminal coiled-coil region HALZ PF02183.13 CCL98342.1 - 6.6 6.5 14.9 0.29 10.8 0.5 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper Nic96 PF04097.9 CCL98344.1 - 1.5e-125 419.7 0.0 2e-125 419.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 ST7 PF04184.7 CCL98344.1 - 0.07 11.3 0.5 0.11 10.6 0.4 1.2 1 0 0 1 1 1 0 ST7 protein MCM PF00493.18 CCL98347.1 - 1.9e-138 460.8 0.1 2.7e-138 460.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CCL98347.1 - 2.6e-32 111.9 31.8 2.6e-32 111.9 22.1 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CCL98347.1 - 9.3e-17 61.6 0.1 2.6e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCL98347.1 - 1.2e-07 31.0 0.0 3.3e-06 26.4 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCL98347.1 - 1.5e-05 24.6 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCL98347.1 - 0.00045 19.8 0.0 0.029 13.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCL98347.1 - 0.0029 17.1 0.1 0.023 14.1 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.9 CCL98347.1 - 0.035 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-TFIIB PF13453.1 CCL98347.1 - 0.13 11.4 1.1 0.25 10.5 0.8 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger ABC_tran PF00005.22 CCL98348.1 - 3.6e-34 118.0 0.0 6.4e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CCL98348.1 - 3.5e-25 88.9 12.5 6.1e-25 88.1 8.7 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 CCL98348.1 - 1.4e-06 28.3 0.1 4.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CCL98348.1 - 2.9e-06 27.4 0.0 0.00057 19.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 CCL98348.1 - 0.0004 19.6 0.0 0.0037 16.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCL98348.1 - 0.002 17.6 0.1 0.0049 16.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCL98348.1 - 0.0043 17.2 0.2 0.029 14.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CCL98348.1 - 0.0058 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCL98348.1 - 0.022 14.1 0.1 0.37 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 CCL98348.1 - 0.072 11.6 0.2 6.1 5.3 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 CCL98348.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.1 CCL98348.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PAT1 PF09770.4 CCL98348.1 - 1.9 6.6 10.2 2.4 6.2 7.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.17 CCL98349.1 - 5e-11 42.0 0.0 7.4e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL98349.1 - 1.2e-09 38.0 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL98349.1 - 1.6e-07 31.0 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FTH PF01827.22 CCL98353.1 - 0.041 13.4 0.4 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 FTH domain F-box-like PF12937.2 CCL98354.1 - 0.022 14.4 0.8 0.057 13.1 0.6 1.7 1 1 0 1 1 1 0 F-box-like Med14 PF08638.6 CCL98355.1 - 5.2e-40 136.7 0.2 1.3e-39 135.4 0.1 1.7 1 0 0 1 1 1 1 Mediator complex subunit MED14 HEAT PF02985.17 CCL98356.1 - 2e-08 33.6 0.4 1.1 9.5 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Pkinase PF00069.20 CCL98356.1 - 2.3e-07 30.2 0.0 4.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.1 CCL98356.1 - 0.00062 19.9 0.0 0.35 11.1 0.0 3.2 2 0 0 2 2 2 2 HEAT repeats Kinase-like PF14531.1 CCL98356.1 - 0.0035 16.3 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CCL98356.1 - 0.023 13.7 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase DASH_Dad2 PF08654.5 CCL98357.1 - 7.4e-09 35.5 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 Peptidase_C25 PF01364.13 CCL98357.1 - 0.0076 15.2 0.0 0.0089 15.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C25 DUF1178 PF06676.6 CCL98357.1 - 0.072 13.2 0.2 0.098 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) HHH_2 PF12826.2 CCL98357.1 - 0.12 12.3 0.5 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif GST_N_3 PF13417.1 CCL98359.1 - 1.2e-13 51.0 0.0 2.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCL98359.1 - 4.8e-12 45.6 0.0 1.3e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCL98359.1 - 0.00016 21.4 0.3 0.00038 20.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCL98359.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCL98359.1 - 0.0017 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Abhydrolase_3 PF07859.8 CCL98360.1 - 6.9e-16 58.4 0.4 1.2e-15 57.6 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL98360.1 - 0.00015 21.5 0.1 0.00023 20.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 CCL98360.1 - 0.00061 18.5 0.0 0.003 16.2 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) DLH PF01738.13 CCL98360.1 - 0.0061 15.8 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family PEPCK_ATP PF01293.15 CCL98361.1 - 5.2e-217 720.9 0.0 6.1e-217 720.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 CCL98361.1 - 0.015 14.7 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCL98361.1 - 0.053 13.8 0.1 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 CCL98361.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCL98361.1 - 0.11 11.8 0.2 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 CCL98363.1 - 2.2e-17 63.4 5.0 1.2e-16 61.0 3.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCL98363.1 - 1.8e-14 54.1 0.0 4.4e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCL98363.1 - 3.8e-07 29.9 0.2 5.9e-05 22.8 0.1 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 CCL98363.1 - 0.0003 20.3 0.0 0.00052 19.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CCL98363.1 - 0.0027 17.7 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TF_Zn_Ribbon PF08271.7 CCL98364.1 - 0.038 13.3 4.5 0.35 10.2 0.2 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding Palm_thioest PF02089.10 CCL98365.1 - 3.4e-60 203.3 0.0 4.1e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 CCL98365.1 - 1e-05 25.2 0.2 0.0019 17.8 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCL98365.1 - 0.0025 17.7 0.1 0.0039 17.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family NAD_binding_9 PF13454.1 CCL98366.1 - 0.00043 20.0 0.0 0.0017 18.1 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding CybS PF05328.7 CCL98367.1 - 6e-34 116.5 0.3 4.5e-33 113.6 0.2 1.9 1 1 0 1 1 1 1 CybS Dynamin_M PF01031.15 CCL98368.1 - 2.2e-30 105.4 0.0 5.5e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 CCL98368.1 - 1.4e-18 67.2 0.0 8e-18 64.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 CCL98368.1 - 4.6e-11 42.4 1.7 1.1e-10 41.2 0.7 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCL98368.1 - 2.6e-05 24.1 0.0 0.0002 21.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCL98368.1 - 0.002 18.6 0.0 0.0068 16.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 CCL98368.1 - 0.0091 15.9 0.1 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCL98368.1 - 0.034 14.4 0.0 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 CCL98368.1 - 0.073 12.6 0.2 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1857 PF08982.6 CCL98369.1 - 1.9e-27 95.7 0.0 2.3e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Aldo_ket_red PF00248.16 CCL98370.1 - 2.4e-52 177.4 0.0 3e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CCL98371.1 - 1.8e-47 161.5 0.0 2.3e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family COX7C PF02935.11 CCL98372.1 - 1.2e-13 50.6 1.4 1.5e-13 50.3 1.0 1.2 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc APH PF01636.18 CCL98373.1 - 2.7e-20 73.1 0.1 4.5e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CCL98373.1 - 0.00019 20.6 0.3 0.00031 19.9 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 CCL98373.1 - 0.00095 17.9 0.0 0.0016 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 CCL98373.1 - 0.0026 17.3 0.1 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Erp_C PF06780.6 CCL98373.1 - 0.04 13.7 0.8 0.11 12.3 0.5 1.7 1 0 0 1 1 1 0 Erp protein C-terminus Lambda_tail_I PF06805.7 CCL98373.1 - 0.095 12.5 0.1 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I DUF1250 PF06855.7 CCL98373.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) Lipase_GDSL PF00657.17 CCL98375.1 - 7.4e-13 48.8 0.0 9.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CCL98375.1 - 1.2e-11 45.1 0.0 3.9e-11 43.3 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family ARD PF03079.9 CCL98377.1 - 7.7e-42 142.8 0.0 8.9e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CCL98377.1 - 4.1e-09 35.7 0.5 8.4e-09 34.8 0.3 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CCL98377.1 - 1.3e-07 31.4 0.2 1.7e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 CCL98377.1 - 0.00071 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 CCL98377.1 - 0.027 13.8 0.1 0.062 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF3337 PF11816.3 CCL98378.1 - 4.2e-48 164.4 0.0 4.3e-47 161.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) MFS_1 PF07690.11 CCL98378.1 - 5.6e-32 110.8 28.5 8.7e-32 110.1 19.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 CCL98378.1 - 1.5e-30 103.8 13.9 5e-08 32.5 0.9 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF1228 PF06779.9 CCL98378.1 - 0.052 13.5 0.1 0.052 13.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF485 PF04341.7 CCL98378.1 - 1.3 8.7 4.5 0.41 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PCI PF01399.22 CCL98379.1 - 2.1e-07 31.1 6.5 6.3e-07 29.6 0.0 3.4 4 0 0 4 4 4 2 PCI domain Ion_trans PF00520.26 CCL98380.1 - 5.5e-99 329.3 83.2 2.2e-32 111.9 8.0 5.0 5 0 0 5 5 5 4 Ion transport protein Ubiq_cyt_C_chap PF03981.7 CCL98381.1 - 2.3e-23 82.6 0.1 1.6e-12 47.5 0.0 3.1 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone PI3Ka PF00613.15 CCL98382.1 - 2.6e-55 186.4 0.1 5e-55 185.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CCL98382.1 - 1.8e-42 145.4 0.0 2.6e-41 141.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CCL98382.1 - 1.4e-40 138.3 0.0 2.5e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 p450 PF00067.17 CCL98383.1 - 2.9e-66 223.8 0.0 1.1e-65 221.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 GTP_cyclohydroI PF01227.17 CCL98383.1 - 0.083 12.1 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase I DUF1295 PF06966.7 CCL98384.1 - 2.5e-35 121.9 12.3 1.8e-34 119.0 8.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CCL98384.1 - 0.043 14.0 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Telomere_Sde2 PF13019.1 CCL98385.1 - 1.3e-53 181.0 0.0 2e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing GTSE1_N PF15259.1 CCL98385.1 - 0.011 15.6 0.8 0.011 15.6 0.5 1.6 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Ufm1 PF03671.9 CCL98385.1 - 0.78 9.5 3.3 0.47 10.2 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin fold modifier 1 protein HD PF01966.17 CCL98386.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.4 1 1 0 1 1 1 1 HD domain F-box-like PF12937.2 CCL98388.1 - 1.7e-06 27.6 0.6 5.1e-06 26.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like MscS_porin PF12795.2 CCL98389.1 - 0.01 15.2 2.4 1.5 8.0 0.1 2.2 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain FlxA PF14282.1 CCL98389.1 - 0.019 14.9 3.4 0.52 10.2 0.2 2.5 2 0 0 2 2 2 0 FlxA-like protein NPV_P10 PF05531.7 CCL98389.1 - 0.033 14.4 1.1 1.7 8.9 1.2 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 CCL98389.1 - 0.04 12.8 0.6 2.7 6.8 0.0 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 CCL98389.1 - 0.052 13.0 0.5 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CCL98389.1 - 0.064 12.8 3.2 0.4 10.2 0.1 2.4 3 0 0 3 3 3 0 IncA protein Matrilin_ccoil PF10393.4 CCL98389.1 - 0.066 12.5 2.1 0.17 11.2 1.5 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4200 PF13863.1 CCL98389.1 - 0.073 13.0 2.5 5.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DivIC PF04977.10 CCL98389.1 - 0.15 11.5 0.5 6.2 6.3 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator Cob_adeno_trans PF01923.13 CCL98389.1 - 0.15 11.8 0.2 0.62 9.8 0.0 1.9 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Adeno_PIX PF03955.9 CCL98389.1 - 0.16 12.4 0.4 0.59 10.6 0.1 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Seryl_tRNA_N PF02403.17 CCL98389.1 - 0.21 11.6 1.2 1.3 9.0 0.0 2.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain WXG100 PF06013.7 CCL98389.1 - 0.34 10.9 1.3 6.9 6.7 0.1 2.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Lipoprotein_20 PF13942.1 CCL98389.1 - 0.47 9.9 3.7 0.54 9.7 0.5 2.3 2 0 0 2 2 2 0 YfhG lipoprotein Phage_GP20 PF06810.6 CCL98389.1 - 0.49 9.8 3.3 7.4 5.9 0.0 2.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 SlyX PF04102.7 CCL98389.1 - 0.72 10.2 5.0 1.5 9.2 0.2 3.5 3 1 0 3 3 3 0 SlyX TMF_DNA_bd PF12329.3 CCL98389.1 - 0.85 9.4 8.1 0.36 10.6 0.7 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.1 CCL98389.1 - 1.2 9.4 5.5 10 6.5 0.2 3.6 5 0 0 5 5 4 0 Snapin/Pallidin F-box-like PF12937.2 CCL98390.1 - 0.00018 21.1 10.8 0.00022 20.8 4.2 3.2 3 1 0 3 3 3 1 F-box-like NUDIX PF00293.23 CCL98392.1 - 9.3e-15 54.4 0.0 1.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SMP PF04927.7 CCL98392.1 - 0.071 13.0 3.8 0.5 10.3 0.8 2.4 2 0 0 2 2 2 0 Seed maturation protein Aminotran_3 PF00202.16 CCL98393.1 - 1e-37 129.7 0.0 2.4e-37 128.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 CCL98393.1 - 2.3e-30 105.7 0.0 3.8e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CCL98393.1 - 0.15 11.7 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IlvN PF07991.7 CCL98394.1 - 5.6e-46 155.9 0.0 9e-46 155.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 CCL98394.1 - 1.7e-37 128.5 0.0 2.8e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain CotJA PF11007.3 CCL98394.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) MARVEL PF01284.18 CCL98395.1 - 3e-09 36.8 10.7 4.6e-09 36.2 7.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain PMT PF02366.13 CCL98395.1 - 0.71 9.1 8.7 0.082 12.2 2.3 2.0 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase zf-Di19 PF05605.7 CCL98398.1 - 0.00035 20.6 6.1 0.021 14.9 2.4 2.8 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding RNHCP PF12647.2 CCL98398.1 - 0.056 13.2 0.2 0.056 13.2 0.1 2.9 3 1 0 3 3 3 0 RNHCP domain zf-C2H2 PF00096.21 CCL98398.1 - 0.4 11.1 6.6 4.1 7.9 0.3 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2197 PF09963.4 CCL98398.1 - 0.72 9.8 8.5 3.1 7.8 0.3 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) L51_S25_CI-B8 PF05047.11 CCL98400.1 - 6.5e-12 44.9 0.1 1.3e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Romo1 PF10247.4 CCL98402.1 - 7.3e-18 64.5 7.3 9.3e-18 64.1 5.0 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Pex2_Pex12 PF04757.9 CCL98403.1 - 1.3e-26 93.4 5.7 3.8e-26 91.9 3.9 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 CCL98403.1 - 1.1e-09 37.9 8.0 2.2e-09 36.9 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCL98403.1 - 1.1e-09 37.7 3.9 1.7e-09 37.1 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCL98403.1 - 4.6e-09 36.1 6.9 7.8e-09 35.4 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCL98403.1 - 6.4e-09 35.3 5.8 1.1e-08 34.5 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCL98403.1 - 1.7e-06 27.6 5.8 3e-06 26.8 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CCL98403.1 - 0.00082 19.4 5.8 0.0019 18.2 4.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger TerY-C PF15616.1 CCL98403.1 - 0.00098 19.0 1.2 0.0017 18.2 0.8 1.3 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_UBOX PF13445.1 CCL98403.1 - 0.0017 18.0 1.6 0.0036 16.9 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCL98403.1 - 0.0037 17.1 6.6 0.0087 15.9 4.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CCL98403.1 - 0.017 14.9 1.4 0.03 14.1 1.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CCL98403.1 - 0.11 12.1 5.8 0.21 11.2 4.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CCL98403.1 - 0.28 10.7 5.9 0.67 9.5 4.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.16 CCL98403.1 - 1.4 8.8 6.7 3.4 7.6 4.7 1.6 1 1 0 1 1 1 0 IBR domain zf-B_box PF00643.19 CCL98403.1 - 2.2 8.2 5.4 1.4 8.8 1.2 2.2 2 0 0 2 2 2 0 B-box zinc finger LSM PF01423.17 CCL98404.1 - 1.5e-14 53.2 1.3 2.1e-14 52.8 0.9 1.2 1 0 0 1 1 1 1 LSM domain Dynein_heavy PF03028.10 CCL98405.1 - 2.5e-182 607.6 0.6 5e-182 606.6 0.0 1.7 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CCL98405.1 - 3.6e-130 434.1 5.9 3.6e-130 434.1 4.1 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CCL98405.1 - 1.9e-77 259.9 0.0 4.3e-77 258.7 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CCL98405.1 - 3.5e-47 160.1 0.2 1.3e-46 158.2 0.0 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CCL98405.1 - 5.7e-45 153.3 0.2 1.1e-43 149.1 0.1 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 CCL98405.1 - 5.5e-40 137.1 5.1 9.2e-40 136.4 3.6 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CCL98405.1 - 1.9e-27 95.6 0.0 6.6e-12 45.3 0.0 6.2 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 CCL98405.1 - 8.2e-21 74.2 0.0 3.4e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 CCL98405.1 - 4.1e-13 49.6 0.2 0.0006 20.0 0.0 5.0 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCL98405.1 - 1.7e-12 47.5 0.0 0.013 15.6 0.0 5.7 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 CCL98405.1 - 1.7e-09 37.7 4.3 0.27 11.1 0.0 5.8 6 0 0 6 6 5 3 AAA domain AAA_18 PF13238.1 CCL98405.1 - 4.2e-08 33.5 0.9 0.0071 16.6 0.0 5.6 5 0 0 5 5 5 1 AAA domain AAA_17 PF13207.1 CCL98405.1 - 1.1e-07 32.6 0.0 0.093 13.5 0.0 6.3 5 0 0 5 5 5 1 AAA domain FtsK_SpoIIIE PF01580.13 CCL98405.1 - 4.8e-07 29.4 0.8 0.17 11.3 0.0 5.3 6 0 0 6 6 5 1 FtsK/SpoIIIE family T2SE PF00437.15 CCL98405.1 - 4.1e-06 25.8 0.0 0.057 12.3 0.0 3.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.1 CCL98405.1 - 5.6e-06 26.0 0.0 0.87 9.3 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain AAA_14 PF13173.1 CCL98405.1 - 9.7e-06 25.5 0.1 0.64 9.9 0.0 4.5 5 0 0 5 5 3 2 AAA domain Mg_chelatase PF01078.16 CCL98405.1 - 1.2e-05 24.5 0.4 0.5 9.4 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CCL98405.1 - 0.00016 21.1 0.0 0.69 9.4 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CCL98405.1 - 0.00097 18.2 0.6 2.3 7.2 0.0 4.5 4 0 0 4 4 4 1 Zeta toxin ABC_tran PF00005.22 CCL98405.1 - 0.0015 18.8 0.1 10 6.4 0.0 4.6 3 0 0 3 3 3 0 ABC transporter IstB_IS21 PF01695.12 CCL98405.1 - 0.0068 15.8 2.9 0.37 10.1 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_16 PF13191.1 CCL98405.1 - 0.0088 16.0 19.9 0.22 11.5 0.1 6.9 8 1 0 9 9 6 1 AAA ATPase domain AAA_25 PF13481.1 CCL98405.1 - 0.0094 15.3 0.4 1.8 7.9 0.0 4.1 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 CCL98405.1 - 0.015 15.4 0.5 46 4.2 0.0 4.7 5 0 0 5 5 4 0 RNA helicase PduV-EutP PF10662.4 CCL98405.1 - 0.022 14.2 0.4 7.4 6.0 0.0 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 CCL98405.1 - 0.026 14.3 0.5 3.6 7.3 0.0 4.0 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit MobB PF03205.9 CCL98405.1 - 0.062 12.9 0.1 24 4.6 0.0 3.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CCL98405.1 - 0.1 12.0 2.1 31 3.9 0.1 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 CCL98405.1 - 0.61 9.4 5.7 8.3 5.7 0.2 4.4 4 0 0 4 4 4 0 AAA-like domain HlyD PF00529.15 CCL98405.1 - 2.4 7.4 19.3 0.19 10.9 8.4 2.3 2 0 0 2 2 2 0 HlyD family secretion protein PLRV_ORF5 PF01690.12 CCL98405.1 - 4.1 6.4 3.8 9.3 5.2 2.6 1.5 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SET PF00856.23 CCL98406.1 - 2.2e-10 41.0 0.1 3.1e-08 34.0 0.0 2.5 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.17 CCL98406.1 - 1.9e-06 27.4 0.1 6.1e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region TilS PF09179.6 CCL98406.1 - 0.0016 18.4 0.1 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 TilS substrate binding domain F-box-like PF12937.2 CCL98407.1 - 5e-09 35.7 1.6 5e-09 35.7 1.1 2.5 2 0 0 2 2 2 1 F-box-like PLDc_2 PF13091.1 CCL98408.1 - 1.1e-07 31.5 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.17 CCL98408.1 - 4.4e-05 23.1 0.1 8.7e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif RE_NgoFVII PF09565.5 CCL98408.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 NgoFVII restriction endonuclease PX PF00787.19 CCL98409.1 - 1.6e-10 40.7 0.1 5.7e-10 38.9 0.1 2.0 1 0 0 1 1 1 1 PX domain PLDc PF00614.17 CCL98409.1 - 2.4e-05 23.9 0.1 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.1 CCL98409.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain PH PF00169.24 CCL98409.1 - 0.031 14.4 0.6 0.1 12.8 0.4 1.9 1 1 0 1 1 1 0 PH domain NYD-SP28_assoc PF14775.1 CCL98410.1 - 0.026 14.2 1.1 0.049 13.3 0.7 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF4630 PF15443.1 CCL98410.1 - 0.076 12.8 0.6 0.96 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) SPC12 PF06645.8 CCL98411.1 - 3.8e-25 87.4 0.5 5.4e-25 87.0 0.4 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Ost4 PF10215.4 CCL98411.1 - 0.0085 15.5 1.2 0.0085 15.5 0.8 1.6 2 0 0 2 2 2 1 Oligosaccaryltransferase Erv26 PF04148.8 CCL98411.1 - 0.048 13.0 0.1 0.052 12.9 0.1 1.1 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 SAP PF02037.22 CCL98412.1 - 0.00039 19.8 0.3 0.0011 18.4 0.1 1.8 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.7 CCL98412.1 - 0.00046 19.8 0.1 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain F-actin_cap_A PF01267.12 CCL98413.1 - 8.7e-78 261.0 0.0 1.8e-77 260.0 0.0 1.4 1 1 0 1 1 1 1 F-actin capping protein alpha subunit SMC_N PF02463.14 CCL98415.1 - 1.1e-28 100.0 0.0 4.1e-28 98.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCL98415.1 - 3.2e-16 60.2 13.7 3.2e-16 60.2 9.5 5.2 3 2 1 4 4 2 1 AAA domain AAA_15 PF13175.1 CCL98415.1 - 9.6e-07 28.1 8.9 9.6e-07 28.1 6.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 CCL98415.1 - 8.4e-06 25.9 0.1 0.0036 17.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain Reo_sigmaC PF04582.7 CCL98415.1 - 0.00013 21.2 13.0 0.00052 19.3 1.4 3.9 3 1 1 4 4 4 1 Reovirus sigma C capsid protein AAA_29 PF13555.1 CCL98415.1 - 0.00016 21.1 0.2 0.0007 19.0 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF2968 PF11180.3 CCL98415.1 - 0.0023 17.3 6.4 0.0023 17.3 4.4 5.8 2 2 4 6 6 4 2 Protein of unknown function (DUF2968) SbcCD_C PF13558.1 CCL98415.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 CCL98415.1 - 0.14 12.4 0.1 0.14 12.4 0.1 5.0 3 2 0 3 3 3 0 ABC transporter Baculo_PEP_C PF04513.7 CCL98415.1 - 0.16 11.8 28.9 0.012 15.4 1.6 5.4 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_27 PF13514.1 CCL98415.1 - 1.5 6.3 70.5 0.03 12.0 21.3 3.6 2 1 1 3 3 3 0 AAA domain RecR PF02132.10 CCL98416.1 - 0.04 13.3 0.7 0.08 12.3 0.5 1.5 1 0 0 1 1 1 0 RecR protein DZR PF12773.2 CCL98416.1 - 0.077 12.8 1.8 0.15 11.8 1.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Glycos_transf_4 PF00953.16 CCL98417.1 - 8e-32 110.2 6.3 8e-32 110.2 4.4 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 ICL PF00463.16 CCL98418.1 - 2.3e-246 818.0 0.1 2.7e-246 817.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCL98418.1 - 3.1e-08 33.1 0.0 5.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.11 CCL98419.1 - 1.5e-30 106.1 72.0 4.1e-22 78.3 26.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 CCL98421.1 - 0.017 14.8 3.6 0.018 14.7 0.6 2.5 2 0 0 2 2 2 0 F-box-like Ribosomal_L24e PF01246.15 CCL98422.1 - 2.3e-28 97.8 0.6 6.5e-28 96.4 0.4 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e UvrD_C PF13361.1 CCL98422.1 - 3.7e-11 43.0 0.0 8.3e-08 32.0 0.0 3.4 3 1 1 4 4 4 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 CCL98422.1 - 2.8e-07 30.6 0.2 9.8e-06 25.6 0.1 2.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCL98422.1 - 1.7e-06 27.6 2.1 0.00024 20.5 0.0 3.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CCL98422.1 - 0.00097 19.2 0.1 0.27 11.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain TPR_11 PF13414.1 CCL98422.1 - 0.0028 17.2 2.8 5.2 6.7 0.3 4.5 3 1 1 4 4 4 1 TPR repeat AAA_12 PF13087.1 CCL98422.1 - 0.011 15.0 0.0 0.032 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF4557 PF15101.1 CCL98422.1 - 1 9.1 7.6 9.4 6.0 3.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) TPR_2 PF07719.12 CCL98422.1 - 1.2 9.2 8.4 20 5.4 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCL98422.1 - 1.7 8.4 8.1 18 5.1 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Lzipper-MIP1 PF14389.1 CCL98424.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_hydro_18 PF00704.23 CCL98427.1 - 7.6e-82 275.4 7.2 7.6e-82 275.4 5.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 CCL98427.1 - 2.8e-09 36.3 15.1 2.8e-09 36.3 10.5 2.3 2 0 0 2 2 2 1 Carbohydrate binding domain Sporozoite_P67 PF05642.6 CCL98427.1 - 3 5.5 19.7 9.2 3.9 13.2 1.8 1 1 1 2 2 2 0 Sporozoite P67 surface antigen F-box-like PF12937.2 CCL98428.1 - 0.0007 19.2 0.1 0.11 12.2 0.1 2.8 2 0 0 2 2 2 2 F-box-like Abhydrolase_6 PF12697.2 CCL98429.1 - 2.4e-23 83.2 0.2 3e-23 82.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98429.1 - 2.4e-09 37.0 0.0 4.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CCL98429.1 - 0.00056 20.1 0.0 0.00074 19.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 CCL98429.1 - 0.00074 19.2 0.0 0.002 17.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCL98429.1 - 0.041 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase SUR7 PF06687.7 CCL98432.1 - 1.2e-21 77.2 10.8 1.6e-21 76.8 7.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Nol1_Nop2_Fmu PF01189.12 CCL98433.1 - 1.6e-101 339.4 0.0 2e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family PCMT PF01135.14 CCL98433.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 CCL98433.1 - 0.0039 16.8 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 CCL98433.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 CCL98433.1 - 0.056 12.9 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FUN14 PF04930.10 CCL98434.1 - 8.8e-18 64.4 0.3 1.3e-17 63.9 0.2 1.3 1 0 0 1 1 1 1 FUN14 family Coprogen_oxidas PF01218.13 CCL98435.1 - 1.2e-87 293.2 0.0 2.8e-87 292.0 0.0 1.6 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Ion_trans PF00520.26 CCL98437.1 - 1.3e-05 24.5 2.1 1.8e-05 24.0 1.5 1.2 1 0 0 1 1 1 1 Ion transport protein BMFP PF04380.8 CCL98437.1 - 0.071 13.2 1.8 0.15 12.2 1.2 1.5 1 0 0 1 1 1 0 Membrane fusogenic activity DUF1516 PF07457.6 CCL98437.1 - 0.09 12.8 0.4 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) DUF2730 PF10805.3 CCL98437.1 - 0.09 12.5 0.2 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) bZIP_2 PF07716.10 CCL98437.1 - 0.78 9.6 5.0 4.3 7.2 1.5 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DUF485 PF04341.7 CCL98438.1 - 2.7 7.7 6.4 0.67 9.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 COesterase PF00135.23 CCL98439.1 - 7.9e-79 265.7 0.0 1.1e-78 265.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCL98439.1 - 5e-09 36.0 1.6 6.2e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCL98439.1 - 0.0014 17.8 0.5 0.005 16.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCL98439.1 - 0.0045 16.7 0.3 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family MARVEL PF01284.18 CCL98440.1 - 6.5 6.5 20.8 11 5.7 14.4 1.4 1 0 0 1 1 1 0 Membrane-associating domain MFS_1 PF07690.11 CCL98441.1 - 1.7e-12 46.7 25.8 2e-12 46.4 17.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ALG3 PF05208.8 CCL98442.1 - 2.2e-119 398.9 16.4 2.7e-119 398.7 11.4 1.0 1 0 0 1 1 1 1 ALG3 protein DUF2198 PF09964.4 CCL98442.1 - 4 7.2 8.0 0.38 10.5 0.8 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) Cellulase PF00150.13 CCL98443.1 - 8.7e-14 51.3 0.0 2.7e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ist1 PF03398.9 CCL98444.1 - 1.1e-25 89.9 0.6 1.7e-25 89.3 0.4 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.13 CCL98444.1 - 5.5e-13 48.8 0.2 8.5e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain HEAT PF02985.17 CCL98446.1 - 1.3e-17 62.2 20.8 0.0013 18.6 0.1 9.2 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 CCL98446.1 - 3.1e-14 52.9 10.5 4.1e-05 23.7 0.0 6.6 4 2 2 6 6 6 4 HEAT repeats HEAT_PBS PF03130.11 CCL98446.1 - 0.0011 19.2 0.2 2.3 8.9 0.0 4.1 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CCL98446.1 - 0.064 13.7 0.1 0.064 13.7 0.1 6.4 6 1 1 7 7 7 0 HEAT-like repeat DUF4042 PF13251.1 CCL98446.1 - 0.13 11.7 0.4 48 3.3 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) Adaptin_N PF01602.15 CCL98446.1 - 0.18 10.1 0.2 0.72 8.1 0.0 2.0 2 1 0 2 2 2 0 Adaptin N terminal region GST_N_3 PF13417.1 CCL98447.1 - 3.8e-14 52.6 0.1 1.1e-13 51.1 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCL98447.1 - 4.4e-07 29.6 0.4 9e-07 28.7 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCL98447.1 - 4.7e-07 29.7 0.1 2e-06 27.7 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCL98447.1 - 0.013 15.9 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCL98447.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1 PF00133.17 CCL98448.1 - 7.1e-207 688.1 0.0 3.2e-206 685.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCL98448.1 - 3.4e-37 127.5 0.1 8e-37 126.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCL98448.1 - 7e-17 61.1 0.1 1e-07 31.0 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCL98448.1 - 6e-12 45.2 0.1 1.5e-07 30.8 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 CCL98448.1 - 0.0019 17.1 0.2 0.0074 15.1 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 CCL98448.1 - 0.11 11.6 0.0 0.77 8.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Nse4_C PF08743.5 CCL98449.1 - 2.1e-26 91.7 0.0 5.3e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal ASXH PF13919.1 CCL98449.1 - 3.2e-14 52.9 1.2 1.6e-13 50.6 0.9 2.1 1 1 0 1 1 1 1 Asx homology domain Nse4-Nse3_bdg PF15412.1 CCL98449.1 - 6.5e-13 48.3 0.2 1.9e-12 46.8 0.2 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE GST_C PF00043.20 CCL98450.1 - 1.7e-05 24.7 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCL98450.1 - 2.5e-05 24.0 0.5 7.2e-05 22.6 0.3 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCL98450.1 - 0.00062 20.2 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCL98450.1 - 0.0051 17.0 0.1 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain F-box PF00646.28 CCL98451.1 - 4.9e-05 22.8 0.1 0.00012 21.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCL98451.1 - 0.0002 20.9 1.4 0.00043 19.9 0.9 1.5 1 0 0 1 1 1 1 F-box-like Redoxin PF08534.5 CCL98453.1 - 1.3e-25 89.6 0.0 1.6e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCL98453.1 - 1.8e-11 43.7 0.0 2.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 CCL98453.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like TcpF PF06340.6 CCL98453.1 - 0.097 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F Tautomerase PF01361.16 CCL98453.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 1 1 0 1 1 1 0 Tautomerase enzyme MRG PF05712.8 CCL98454.1 - 6.6e-49 165.4 0.0 1.1e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 MRG Pkinase PF00069.20 CCL98454.1 - 1.8e-28 99.4 0.0 2.8e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98454.1 - 2.4e-09 36.6 0.0 4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Tudor-knot PF11717.3 CCL98454.1 - 2.3e-08 33.5 0.6 4.1e-08 32.8 0.4 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain FAM217 PF15344.1 CCL98454.1 - 0.0046 16.5 1.4 0.0073 15.8 1.0 1.2 1 0 0 1 1 1 1 FAM217 family APH PF01636.18 CCL98454.1 - 0.057 13.1 0.2 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CCL98454.1 - 0.12 11.2 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Hce2 PF14856.1 CCL98455.1 - 0.0098 15.7 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor NifU_N PF01592.11 CCL98455.1 - 0.029 14.3 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 NifU-like N terminal domain Mago_nashi PF02792.9 CCL98456.1 - 1.8e-74 248.2 0.4 2.1e-74 247.9 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 CCL98456.1 - 0.16 11.7 0.3 0.31 10.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) Ribosomal_S10 PF00338.17 CCL98457.1 - 1.7e-21 75.8 0.1 4.5e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e DUF462 PF04315.7 CCL98457.1 - 0.2 11.0 1.0 1.2 8.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF462 DUF4451 PF14616.1 CCL98458.1 - 4.6e-13 49.0 14.0 5.8e-07 29.3 0.0 3.5 3 1 1 4 4 4 2 Domain of unknown function (DUF4451) EMP24_GP25L PF01105.19 CCL98459.1 - 2.2e-25 89.4 0.0 2.5e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Aldedh PF00171.17 CCL98460.1 - 7.2e-118 393.8 0.0 8e-118 393.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCL98460.1 - 4.4e-06 25.6 0.0 7.2e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) BAR_2 PF10455.4 CCL98461.1 - 8.2e-52 175.9 0.3 5.9e-29 100.8 0.0 2.0 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CCL98461.1 - 4.3e-15 55.8 1.4 3.5e-14 52.8 1.0 1.9 1 1 0 1 1 1 1 BAR domain Phasin PF05597.6 CCL98461.1 - 0.056 13.2 2.1 0.082 12.6 0.1 2.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) LigT_PEase PF02834.11 CCL98461.1 - 0.1 12.6 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase Proteasome PF00227.21 CCL98462.1 - 4.8e-48 162.9 0.0 5.9e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CCL98462.1 - 5.9e-12 44.6 0.3 1.2e-11 43.6 0.2 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal SpoIIE PF07228.7 CCL98463.1 - 0.0012 18.6 0.0 0.0064 16.2 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CCL98463.1 - 0.0062 15.9 0.7 0.69 9.2 0.1 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCL98463.1 - 0.1 11.9 0.3 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C SOG2 PF10428.4 CCL98463.1 - 0.33 9.5 5.2 0.71 8.4 3.6 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Mito_fiss_reg PF05308.6 CCL98463.1 - 3.1 7.0 7.7 5.4 6.3 3.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator MFS_1 PF07690.11 CCL98464.1 - 1.5e-19 69.9 61.9 3.7e-17 62.0 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCL98464.1 - 4.3e-07 28.6 32.4 1.4e-06 26.9 13.9 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein F-box-like PF12937.2 CCL98465.1 - 0.0075 15.9 2.4 0.0075 15.9 1.7 2.3 3 0 0 3 3 3 1 F-box-like AAA PF00004.24 CCL98466.1 - 1.3e-55 187.2 0.0 1.1e-43 148.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CCL98466.1 - 3e-22 78.4 0.3 8.4e-22 77.0 0.2 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CCL98466.1 - 1.5e-09 38.0 7.8 0.006 16.5 0.1 5.3 3 2 2 6 6 5 2 AAA ATPase domain AAA_17 PF13207.1 CCL98466.1 - 9.5e-08 32.8 0.0 0.0043 17.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCL98466.1 - 7.1e-07 29.4 1.0 0.18 11.9 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCL98466.1 - 1.2e-06 28.4 0.0 0.059 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CCL98466.1 - 2.6e-06 26.6 0.0 0.0048 15.9 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CCL98466.1 - 1.4e-05 24.2 0.0 0.13 11.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.9 CCL98466.1 - 4.4e-05 23.4 0.0 0.038 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CCL98466.1 - 8e-05 22.3 0.0 0.34 10.7 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 CCL98466.1 - 0.00013 21.6 0.2 0.42 10.2 0.0 3.6 3 1 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 CCL98466.1 - 0.00027 21.0 0.0 0.9 9.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 CCL98466.1 - 0.00034 20.3 0.0 0.15 11.7 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase Bac_DnaA PF00308.13 CCL98466.1 - 0.00036 20.2 0.0 0.024 14.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein ABC_tran PF00005.22 CCL98466.1 - 0.00038 20.7 0.0 0.096 12.9 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 CCL98466.1 - 0.00039 20.2 0.1 0.09 12.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 CCL98466.1 - 0.00044 20.5 0.0 0.77 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCL98466.1 - 0.00076 19.2 0.0 0.46 10.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCL98466.1 - 0.0029 17.0 4.4 1.6 8.0 0.1 4.5 3 2 1 5 5 4 1 AAA domain TIP49 PF06068.8 CCL98466.1 - 0.003 16.3 0.0 0.085 11.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 CCL98466.1 - 0.0031 17.1 1.4 2.2 7.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CCL98466.1 - 0.0031 16.4 0.1 1.5 7.6 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain FtsK_SpoIIIE PF01580.13 CCL98466.1 - 0.0072 15.8 0.0 0.037 13.4 0.0 2.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family Rad17 PF03215.10 CCL98466.1 - 0.0082 14.8 0.0 0.53 8.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 CCL98466.1 - 0.0088 15.5 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CCL98466.1 - 0.0088 15.0 1.1 2.8 6.8 0.0 2.7 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 CCL98466.1 - 0.01 15.4 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 CCL98466.1 - 0.011 14.6 0.0 0.55 9.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 CCL98466.1 - 0.014 14.8 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 CCL98466.1 - 0.02 14.3 0.0 3.3 7.1 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 CCL98466.1 - 0.024 13.6 0.0 0.11 11.4 0.0 2.1 2 1 1 3 3 3 0 KAP family P-loop domain AAA_29 PF13555.1 CCL98466.1 - 0.026 14.0 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CCL98466.1 - 0.028 13.8 0.2 0.15 11.4 0.0 2.3 2 1 1 3 3 3 0 AAA-like domain AAA_3 PF07726.6 CCL98466.1 - 0.058 13.0 0.0 0.67 9.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 CCL98466.1 - 0.065 12.6 0.3 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 CCL98466.1 - 0.065 12.3 0.2 0.65 9.1 0.0 2.4 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.1 CCL98466.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family SKI PF01202.17 CCL98466.1 - 0.098 12.5 0.2 0.49 10.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase DUF258 PF03193.11 CCL98466.1 - 0.14 11.3 0.0 0.36 9.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 CCL98466.1 - 0.25 10.4 0.0 7.3 5.6 0.0 2.5 2 0 0 2 2 2 0 KaiC Saccharop_dh PF03435.13 CCL98467.1 - 1.9e-71 241.0 0.0 4.2e-71 239.9 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 CCL98467.1 - 1.1e-12 47.8 0.0 1.8e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 CCL98467.1 - 2.3e-09 37.3 0.0 2e-08 34.3 0.0 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_DH PF01488.15 CCL98467.1 - 0.0083 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Stanniocalcin PF03298.8 CCL98467.1 - 0.019 13.9 0.1 0.088 11.8 0.0 1.9 2 0 0 2 2 2 0 Stanniocalcin family Mid1 PF12929.2 CCL98468.1 - 1.6e-73 247.8 0.0 2.1e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 CCL98468.1 - 0.14 12.4 3.2 1.6 9.1 0.4 2.3 2 0 0 2 2 2 0 Fz domain DnaJ PF00226.26 CCL98469.1 - 3.6e-20 71.4 0.1 7.7e-20 70.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 CCL98469.1 - 8.3e-18 63.8 2.2 0.00013 21.5 0.0 6.3 2 2 5 7 7 7 6 TPR repeat TPR_2 PF07719.12 CCL98469.1 - 6.6e-16 56.8 2.2 0.7 9.9 0.0 9.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCL98469.1 - 1.3e-11 44.7 4.7 0.0038 17.8 0.3 6.3 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCL98469.1 - 8.6e-11 40.9 0.1 0.068 12.8 0.0 7.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCL98469.1 - 2.2e-10 40.2 12.1 0.0082 15.9 0.1 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCL98469.1 - 3.8e-10 39.4 0.5 1.2 9.0 0.0 5.4 6 0 0 6 6 6 4 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 CCL98469.1 - 4.2e-09 36.6 9.0 0.04 14.2 0.0 5.3 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCL98469.1 - 6.9e-09 35.5 6.6 0.053 13.4 0.0 5.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCL98469.1 - 3.1e-06 27.3 14.8 0.17 12.6 0.2 7.0 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCL98469.1 - 0.0074 15.9 0.0 9.4 6.2 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCL98469.1 - 0.011 16.1 3.6 29 5.3 0.0 5.8 6 1 0 6 6 4 0 Tetratricopeptide repeat Thiolase_N PF00108.18 CCL98469.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Alkyl_sulf_dimr PF14863.1 CCL98469.1 - 0.11 12.6 0.8 0.36 11.0 0.1 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation MIT PF04212.13 CCL98469.1 - 0.71 9.8 7.5 0.28 11.0 0.3 3.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain FAD_binding_3 PF01494.14 CCL98471.1 - 1.1e-18 67.3 0.0 1.6e-17 63.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCL98471.1 - 5.4e-06 26.3 0.1 0.00023 21.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CCL98471.1 - 0.01 14.4 0.1 0.049 12.2 0.0 1.8 1 1 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.14 CCL98472.1 - 5.5e-24 84.8 0.0 8.5e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 CCL98472.1 - 7.7e-06 24.7 0.0 1.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 CCL98472.1 - 0.00084 19.1 0.3 0.0044 16.8 0.1 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CCL98472.1 - 0.001 19.0 0.4 0.0022 17.9 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCL98472.1 - 0.0032 17.5 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCL98472.1 - 0.0063 15.4 0.6 0.012 14.5 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 CCL98472.1 - 0.015 14.1 0.0 0.16 10.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.9 CCL98472.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Img2 PF05046.9 CCL98472.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) MFS_1 PF07690.11 CCL98473.1 - 8.1e-11 41.2 44.2 3.9e-08 32.3 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cerato-platanin PF07249.7 CCL98474.1 - 4.5e-46 155.7 2.6 5.6e-46 155.4 1.8 1.1 1 0 0 1 1 1 1 Cerato-platanin DUF21 PF01595.15 CCL98475.1 - 1.1e-30 106.2 0.9 1.8e-30 105.6 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CCL98475.1 - 0.00046 19.9 0.6 0.83 9.4 0.0 3.5 3 0 0 3 3 3 2 CBS domain p450 PF00067.17 CCL98477.1 - 6.3e-74 249.1 0.0 1.2e-73 248.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_C12 PF01088.16 CCL98478.1 - 3.2e-47 160.4 0.0 8.6e-46 155.8 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Abhydrolase_6 PF12697.2 CCL98479.1 - 6.8e-25 88.2 0.0 8.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98479.1 - 4e-14 52.7 0.0 6.2e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL98479.1 - 1.4e-09 37.8 0.0 1.4e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CCL98479.1 - 0.00015 21.3 0.1 0.00037 20.0 0.0 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 CCL98479.1 - 0.00056 20.2 0.1 0.00083 19.6 0.1 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 CCL98479.1 - 0.0041 16.6 0.0 0.099 12.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 CCL98479.1 - 0.0051 16.2 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase COesterase PF00135.23 CCL98479.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Clat_adaptor_s PF01217.15 CCL98481.1 - 2.4e-17 62.9 0.0 4.2e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Abhydrolase_6 PF12697.2 CCL98482.1 - 5.9e-20 72.1 0.0 7.5e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98482.1 - 7.2e-18 64.9 0.0 4.8e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL98482.1 - 0.00022 21.0 0.0 0.0012 18.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CCL98482.1 - 0.0012 18.2 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 CCL98483.1 - 4.2e-17 62.7 1.7 1.3e-16 61.1 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCL98483.1 - 0.00049 19.8 0.0 0.00087 19.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98483.1 - 0.0021 17.6 0.0 0.0066 16.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltrans_Mon PF14314.1 CCL98483.1 - 0.1 10.4 0.0 0.16 9.8 0.0 1.2 1 0 0 1 1 1 0 Virus-capping methyltransferase Abhydrolase_6 PF12697.2 CCL98485.1 - 2.8e-21 76.4 0.0 3.6e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98485.1 - 3.4e-13 49.6 0.0 1.1e-12 48.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL98485.1 - 5.8e-08 32.6 0.0 3.7e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCL98485.1 - 0.0028 17.1 0.0 0.056 12.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 CCL98485.1 - 0.0031 16.9 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) SPX PF03105.14 CCL98486.1 - 1.3e-14 54.6 0.0 4.7e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 SPX domain zf-C3HC4 PF00097.20 CCL98486.1 - 5.4e-07 29.1 10.8 1e-06 28.3 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCL98486.1 - 7.4e-07 28.9 9.8 1.4e-06 28.0 6.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CCL98486.1 - 2e-06 27.7 11.8 3.7e-06 26.8 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCL98486.1 - 3.7e-06 26.6 10.3 6.9e-06 25.7 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCL98486.1 - 5.3e-06 26.0 8.7 9.5e-06 25.1 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCL98486.1 - 0.00018 21.1 9.3 0.00036 20.1 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 CCL98486.1 - 0.0022 17.5 3.7 0.0047 16.4 2.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CCL98486.1 - 0.032 13.9 8.4 0.097 12.4 5.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 CCL98486.1 - 0.097 12.5 2.3 0.18 11.6 1.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCL98486.1 - 0.16 12.1 8.1 0.44 10.7 5.6 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CCL98486.1 - 0.22 11.3 3.9 0.47 10.2 2.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CCL98486.1 - 0.39 10.2 6.3 1.2 8.7 4.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 CCL98486.1 - 3.6 7.1 8.3 6.6 6.3 5.8 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Cellulase PF00150.13 CCL98487.1 - 2e-29 102.6 0.9 3.1e-29 102.0 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 CCL98488.1 - 1.4e-31 109.7 0.4 2.2e-31 109.0 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M24 PF00557.19 CCL98489.1 - 6.5e-55 185.9 0.0 1.1e-54 185.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 RNase_PH PF01138.16 CCL98489.1 - 2.7e-16 60.0 0.0 5.4e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 cIII PF08134.6 CCL98489.1 - 0.15 11.6 0.3 0.34 10.5 0.2 1.6 1 0 0 1 1 1 0 cIII protein family SNF5 PF04855.7 CCL98490.1 - 4.7e-58 196.5 0.0 9.9e-58 195.4 0.0 1.5 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 CBFD_NFYB_HMF PF00808.18 CCL98491.1 - 2.3e-16 59.5 1.2 4.5e-16 58.6 0.8 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCL98491.1 - 1.4e-09 37.9 0.7 3.2e-09 36.7 0.5 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Sld5 PF05916.6 CCL98491.1 - 0.00028 21.1 0.8 0.00073 19.8 0.1 2.0 2 0 0 2 2 2 1 GINS complex protein BUD22 PF09073.5 CCL98491.1 - 0.00074 18.7 15.3 0.0011 18.1 10.6 1.3 1 0 0 1 1 1 1 BUD22 TAFII28 PF04719.9 CCL98491.1 - 0.028 14.1 1.2 0.062 13.0 0.8 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region MDM1 PF15501.1 CCL98491.1 - 0.077 11.9 10.7 0.11 11.4 7.4 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 IER PF05760.7 CCL98491.1 - 0.11 12.3 3.2 0.18 11.7 2.2 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) A_deaminase_N PF08451.6 CCL98491.1 - 0.12 12.3 3.6 0.29 11.1 2.5 1.6 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Pox_Ag35 PF03286.9 CCL98491.1 - 0.83 9.1 11.2 1.7 8.1 7.8 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 CCL98491.1 - 5.8 4.7 20.9 8.5 4.1 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family Sulfate_transp PF00916.15 CCL98492.1 - 1.4e-42 145.6 7.1 1.4e-42 145.6 4.9 1.8 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 CCL98492.1 - 3.4e-14 52.4 0.0 6.3e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 CCL98492.1 - 1.1e-09 37.7 0.1 2.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain rRNA_proc-arch PF13234.1 CCL98493.1 - 2.3e-94 315.5 0.0 4.2e-94 314.6 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CCL98493.1 - 4.1e-58 195.5 0.5 8.4e-58 194.5 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCL98493.1 - 8.5e-15 54.6 0.0 2.5e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCL98493.1 - 4.5e-07 29.6 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 CCL98493.1 - 0.043 12.7 0.0 0.11 11.3 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Cyt-b5 PF00173.23 CCL98494.1 - 4e-10 39.3 0.0 5.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.17 CCL98495.1 - 1.8e-64 217.9 0.0 9.5e-64 215.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 CCL98496.1 - 1.7e-14 53.8 0.0 4.8e-14 52.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CCL98496.1 - 1.2e-10 40.8 0.2 4.2e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 CCL98496.1 - 6.5e-08 32.4 0.0 8.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCL98496.1 - 7.2e-05 22.1 0.0 0.2 10.8 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 CCL98496.1 - 0.00019 20.3 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 CCL98496.1 - 0.00022 21.1 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 CCL98496.1 - 0.00081 18.1 0.0 0.0011 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Chlorophyllase PF07224.6 CCL98496.1 - 0.059 12.1 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.11 CCL98496.1 - 0.085 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HET PF06985.6 CCL98497.1 - 2.3e-17 63.4 4.3 1.4e-14 54.4 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box PF00646.28 CCL98498.1 - 1.5e-09 37.2 0.5 3.4e-09 36.1 0.1 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CCL98498.1 - 2.7e-07 30.1 0.6 8e-07 28.6 0.4 1.8 1 0 0 1 1 1 1 F-box-like RhoGEF PF00621.15 CCL98499.1 - 6.7e-19 68.4 0.0 1.1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain NUDIX_2 PF13869.1 CCL98500.1 - 2.6e-85 284.5 0.0 2.9e-85 284.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Glyco_hydro_61 PF03443.9 CCL98501.1 - 4.3e-54 183.6 0.0 5.5e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Zip PF02535.17 CCL98502.1 - 6.9e-47 160.0 16.2 3.7e-46 157.6 11.3 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1212 PF06738.7 CCL98503.1 - 2e-30 105.7 3.0 2e-30 105.7 2.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CCL98503.1 - 4.3e-13 49.3 11.3 4.3e-13 49.3 7.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) SNF2_N PF00176.18 CCL98504.1 - 1.9e-70 237.0 0.0 2.4e-69 233.4 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCL98504.1 - 1.6e-11 43.9 0.0 2.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CCL98504.1 - 2.2e-05 24.0 2.3 5.3e-05 22.8 1.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCL98504.1 - 0.0079 15.8 1.9 0.022 14.3 1.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CCL98504.1 - 0.018 14.8 0.0 0.42 10.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 CCL98504.1 - 0.034 13.8 0.0 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 CCL98504.1 - 0.13 12.0 7.1 0.33 10.8 4.2 2.2 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 CCL98504.1 - 0.36 10.8 4.8 1.4 9.0 3.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribonucleas_3_3 PF14622.1 CCL98505.1 - 2e-10 40.7 0.0 3.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 CCL98505.1 - 8e-07 29.5 0.1 1.8e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 CCL98505.1 - 0.0016 18.8 0.0 0.0058 17.0 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain SNF2_N PF00176.18 CCL98506.1 - 6.9e-63 212.2 0.1 1.2e-62 211.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 CCL98506.1 - 6.7e-18 64.5 0.2 1.3e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 CCL98506.1 - 8.4e-16 57.6 0.0 2.6e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 CCL98506.1 - 1.7e-06 27.4 0.4 4.5e-05 22.8 0.0 2.9 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain Chromo PF00385.19 CCL98506.1 - 0.00011 21.8 0.4 0.026 14.1 0.0 3.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 CCL98506.1 - 8.6 6.1 11.0 5.3 6.8 0.1 3.8 4 0 0 4 4 4 0 PHD-finger Sec8_exocyst PF04048.9 CCL98507.1 - 1.6e-29 102.3 1.8 6.8e-29 100.3 0.2 2.6 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CCL98507.1 - 1.1e-08 34.3 0.8 1.8e-08 33.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Pkr1 PF08636.5 CCL98507.1 - 0.24 11.4 1.8 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 ER protein Pkr1 Cellulase PF00150.13 CCL98509.1 - 1.7e-41 142.2 0.5 2.2e-41 141.9 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 CCL98510.1 - 5.9e-45 153.6 0.0 7.8e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MMR_HSR1 PF01926.18 CCL98511.1 - 2.4e-15 56.5 0.0 1.4e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCL98511.1 - 3.5e-05 23.1 0.1 0.00023 20.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CCL98511.1 - 0.00045 19.4 0.0 0.0009 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCL98511.1 - 0.0026 16.8 0.0 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 CCL98511.1 - 0.011 15.5 0.1 0.031 14.1 0.1 1.7 1 0 0 1 1 1 0 Dynamin family Miro PF08477.8 CCL98511.1 - 0.025 15.0 0.0 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Pkinase PF00069.20 CCL98512.1 - 1.8e-43 148.6 0.0 2.3e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98512.1 - 1.7e-27 96.1 0.0 2.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCL98512.1 - 1.9e-12 47.1 0.1 4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 CCL98512.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Esterase PF00756.15 CCL98513.1 - 2.3e-39 135.3 0.0 2.8e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 CCL98513.1 - 0.0089 14.9 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 CCL98513.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pilin_PilX PF11530.3 CCL98513.1 - 0.063 12.9 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 Minor type IV pilin, PilX PGAP1 PF07819.8 CCL98514.1 - 4.5e-07 29.6 0.1 8.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CCL98514.1 - 2.5e-05 24.2 0.1 4.1e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCL98514.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CCL98514.1 - 0.00097 18.2 0.0 0.0022 17.1 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 CCL98514.1 - 0.002 17.6 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 CCL98514.1 - 0.0031 16.8 0.0 0.01 15.1 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 CCL98514.1 - 0.0035 16.3 0.0 0.0053 15.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Choline_kinase PF01633.15 CCL98514.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Lipase_3 PF01764.20 CCL98514.1 - 0.045 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AAA_5 PF07728.9 CCL98515.1 - 1e-121 401.0 0.0 1.1e-19 70.5 0.0 9.7 8 1 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 CCL98515.1 - 3.8e-25 88.5 0.1 0.00013 22.1 0.0 6.8 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 CCL98515.1 - 9.2e-24 83.5 0.0 1.5e-07 31.0 0.0 7.4 7 0 0 7 7 7 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCL98515.1 - 1.3e-22 80.2 0.1 0.0076 16.3 0.0 8.1 7 0 0 7 7 7 5 AAA domain AAA_16 PF13191.1 CCL98515.1 - 1.2e-18 67.7 23.4 0.00085 19.3 0.0 9.5 9 1 0 9 9 8 4 AAA ATPase domain AAA_17 PF13207.1 CCL98515.1 - 2.9e-18 66.8 0.0 0.0088 16.8 0.0 6.5 5 0 0 5 5 5 4 AAA domain Sigma54_activat PF00158.21 CCL98515.1 - 3e-17 62.6 0.0 0.0046 16.4 0.0 5.9 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_18 PF13238.1 CCL98515.1 - 9.2e-17 61.5 0.2 0.0013 18.9 0.0 6.2 5 0 0 5 5 5 3 AAA domain Sigma54_activ_2 PF14532.1 CCL98515.1 - 4.7e-15 55.8 0.2 7.8e-05 22.7 0.0 5.9 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_14 PF13173.1 CCL98515.1 - 8.5e-15 54.7 0.0 0.0017 18.2 0.0 8.0 9 0 0 9 9 7 2 AAA domain AAA_19 PF13245.1 CCL98515.1 - 3.1e-12 46.0 8.7 0.0022 17.6 0.1 6.7 6 0 0 6 6 6 2 Part of AAA domain ABC_tran PF00005.22 CCL98515.1 - 5.1e-12 46.2 1.9 0.068 13.4 0.0 6.1 6 0 0 6 6 4 3 ABC transporter AAA_33 PF13671.1 CCL98515.1 - 1.1e-11 44.7 0.0 0.16 11.8 0.0 6.4 5 1 0 5 5 5 3 AAA domain AAA_28 PF13521.1 CCL98515.1 - 2.8e-10 40.3 7.3 0.42 10.5 0.0 6.5 6 0 0 6 6 5 3 AAA domain UPF0079 PF02367.12 CCL98515.1 - 6.6e-10 38.6 0.1 0.48 10.0 0.0 5.4 6 0 0 6 6 5 2 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CCL98515.1 - 2.7e-09 36.3 0.0 1.8 7.6 0.0 6.7 7 0 0 7 7 6 2 Zeta toxin T2SE PF00437.15 CCL98515.1 - 3.2e-09 36.0 0.1 0.13 11.0 0.0 5.6 6 0 0 6 6 6 2 Type II/IV secretion system protein Miro PF08477.8 CCL98515.1 - 1.1e-08 35.5 0.4 2.7 8.4 0.0 5.8 5 0 0 5 5 5 0 Miro-like protein AAA_29 PF13555.1 CCL98515.1 - 2.6e-08 33.2 2.3 0.3 10.6 0.1 6.7 7 0 0 7 7 7 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CCL98515.1 - 5.8e-08 32.1 0.7 8.4 5.4 0.0 7.9 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 CCL98515.1 - 6e-08 32.5 1.7 1.3 8.7 0.0 5.5 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CCL98515.1 - 8.7e-08 31.9 0.8 2.2 7.9 0.0 5.2 4 0 0 4 4 4 2 NACHT domain DUF815 PF05673.8 CCL98515.1 - 1.9e-07 30.3 0.2 0.77 8.6 0.0 4.9 5 0 0 5 5 5 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 CCL98515.1 - 3.4e-07 30.4 0.3 10 6.3 0.0 6.2 7 0 0 7 7 5 0 RNA helicase RuvB_N PF05496.7 CCL98515.1 - 1.9e-06 27.0 1.0 2.5 7.0 0.0 6.0 6 0 0 6 6 6 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 CCL98515.1 - 2e-06 27.7 0.1 12 5.4 0.0 6.4 6 0 0 6 6 6 0 Archaeal ATPase AAA_23 PF13476.1 CCL98515.1 - 4.2e-06 27.2 0.3 2.5 8.3 0.0 5.4 5 0 0 5 5 5 1 AAA domain DUF258 PF03193.11 CCL98515.1 - 6e-06 25.5 0.6 1.9 7.6 0.0 4.6 4 0 0 4 4 4 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CCL98515.1 - 7.4e-06 25.5 0.1 0.18 11.2 0.0 4.7 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 CCL98515.1 - 9.1e-06 25.2 7.8 1.4 8.2 0.0 6.3 6 0 0 6 6 6 1 AAA domain SRP54 PF00448.17 CCL98515.1 - 5.8e-05 22.6 0.1 13 5.1 0.0 4.7 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 CCL98515.1 - 0.00033 20.3 0.2 3.2 7.2 0.0 4.5 5 0 0 5 5 4 0 AAA domain Dynein_heavy PF03028.10 CCL98515.1 - 0.0039 15.3 0.0 1.1 7.1 0.0 3.5 4 0 0 4 4 4 1 Dynein heavy chain and region D6 of dynein motor cobW PF02492.14 CCL98515.1 - 0.0057 16.1 1.0 26 4.2 0.0 4.7 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.10 CCL98515.1 - 0.0062 16.3 0.0 3.8 7.2 0.0 3.1 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 CCL98515.1 - 0.0069 15.9 0.8 1.8 8.0 0.0 4.3 6 0 0 6 6 3 1 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.1 CCL98515.1 - 0.014 15.4 0.0 1.5 8.7 0.0 3.3 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.10 CCL98515.1 - 0.014 15.1 2.4 10 5.7 0.0 4.4 4 0 0 4 4 4 0 NTPase SRPRB PF09439.5 CCL98515.1 - 0.027 13.7 0.5 20 4.3 0.0 4.5 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 CCL98515.1 - 0.048 13.1 2.9 3.1 7.2 0.0 3.9 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.2 CCL98515.1 - 0.052 12.6 0.0 1 8.3 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 vWA-TerF-like PF10138.4 CCL98515.1 - 0.053 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus PhoH PF02562.11 CCL98515.1 - 0.1 11.8 0.5 14 4.8 0.0 3.5 4 0 0 4 4 3 0 PhoH-like protein CbiA PF01656.18 CCL98515.1 - 0.11 11.8 0.4 1.1 8.6 0.0 2.7 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain KaiC PF06745.8 CCL98515.1 - 0.12 11.4 1.0 12 4.9 0.0 3.2 4 0 0 4 4 2 0 KaiC TIP49 PF06068.8 CCL98515.1 - 0.15 10.7 0.2 19 3.7 0.0 3.3 4 0 0 4 4 4 0 TIP49 C-terminus Dynamin_N PF00350.18 CCL98515.1 - 0.15 11.8 0.8 6.8 6.4 0.0 3.5 3 0 0 3 3 3 0 Dynamin family DUF3289 PF11692.3 CCL98515.1 - 0.21 10.8 0.0 0.42 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) Gtr1_RagA PF04670.7 CCL98515.1 - 0.25 10.4 0.3 13 4.7 0.0 3.6 4 0 0 4 4 3 0 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.9 CCL98515.1 - 0.27 10.1 0.0 40 3.0 0.0 3.3 3 0 0 3 3 3 0 KAP family P-loop domain AAA_6 PF12774.2 CCL98515.1 - 0.61 9.5 0.0 27 4.1 0.0 3.7 6 0 0 6 6 3 0 Hydrolytic ATP binding site of dynein motor region D1 MMR_HSR1 PF01926.18 CCL98515.1 - 0.74 9.7 3.3 29 4.6 0.0 4.3 5 0 0 5 5 4 0 50S ribosome-binding GTPase PIF1 PF05970.9 CCL98515.1 - 1.3 7.9 0.1 71 2.1 0.0 3.6 5 0 0 5 5 5 0 PIF1-like helicase Rad17 PF03215.10 CCL98515.1 - 1.8 7.1 1.8 47 2.4 0.0 3.3 5 0 0 5 5 4 0 Rad17 cell cycle checkpoint protein Ras PF00071.17 CCL98515.1 - 3.5 7.0 3.2 29 3.9 0.0 3.4 4 0 0 4 4 4 0 Ras family Sugar_tr PF00083.19 CCL98516.1 - 2.3e-17 62.7 18.0 9.7e-15 54.0 12.5 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCL98516.1 - 4.8e-14 51.8 38.1 2.6e-13 49.4 23.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 CCL98516.1 - 0.14 12.5 0.1 2.6 8.4 0.0 2.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Avl9 PF09794.4 CCL98519.1 - 1e-125 419.1 0.0 1.4e-125 418.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 CCL98519.1 - 2.4e-10 40.1 1.0 0.00015 21.1 1.3 3.3 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 CCL98519.1 - 2.7e-10 39.9 0.0 8.1e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis COesterase PF00135.23 CCL98520.1 - 4.7e-104 349.0 0.0 6.8e-104 348.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCL98520.1 - 0.00026 20.6 0.3 0.00087 18.9 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCL98520.1 - 0.00028 20.1 0.0 0.00039 19.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CCL98520.1 - 0.058 13.2 0.0 0.12 12.1 0.0 1.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCL98520.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family STE3 PF02076.10 CCL98521.1 - 2e-79 266.6 18.2 2.3e-79 266.4 12.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3421 PF11901.3 CCL98522.1 - 3.4e-27 94.5 0.1 1.2e-09 37.9 0.0 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) CBM_5_12 PF02839.9 CCL98522.1 - 2e-06 27.2 0.9 6.3e-06 25.6 0.6 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain DUF1974 PF09317.6 CCL98522.1 - 0.053 12.9 0.0 0.078 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Mus7 PF09462.5 CCL98524.1 - 6.8e-81 272.9 2.7 2.2e-80 271.2 1.9 1.8 1 1 0 1 1 1 1 Mus7/MMS22 family Abhydrolase_6 PF12697.2 CCL98525.1 - 4.1e-12 46.4 0.7 1.1e-11 45.0 0.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCL98525.1 - 1e-11 44.7 0.0 2.9e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DRMBL PF07522.9 CCL98525.1 - 7.9e-07 29.1 0.0 2.7e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lipase_3 PF01764.20 CCL98525.1 - 2.6e-06 27.0 0.0 5.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 CCL98525.1 - 0.00054 19.5 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CCL98525.1 - 0.0051 17.0 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Cutinase PF01083.17 CCL98525.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 CCL98525.1 - 0.025 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 CCL98525.1 - 0.14 11.6 0.1 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF1749 PF08538.5 CCL98525.1 - 0.2 10.4 0.0 19 3.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Ribosomal_L33 PF00471.15 CCL98526.1 - 2.2e-08 34.1 0.0 3.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Ebp2 PF05890.7 CCL98529.1 - 2.1e-79 266.6 10.6 2.6e-79 266.3 7.3 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 CRISPR_Cas2 PF09827.4 CCL98531.1 - 0.07 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Glyco_hydro_28 PF00295.12 CCL98533.1 - 6.5e-32 110.7 1.0 8.7e-32 110.3 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 AAA_11 PF13086.1 CCL98536.1 - 4.7e-28 98.3 0.0 1.4e-26 93.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CCL98536.1 - 1.8e-09 37.5 0.0 3.8e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.1 CCL98536.1 - 7.4e-09 35.2 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCL98536.1 - 3.1e-08 33.2 0.0 7.5e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CCL98536.1 - 0.0026 17.7 0.9 0.026 14.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 CCL98536.1 - 0.0068 15.8 0.0 0.037 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_14 PF13173.1 CCL98536.1 - 0.0078 16.1 0.1 0.24 11.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCL98536.1 - 0.02 15.2 0.0 0.07 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCL98536.1 - 0.022 14.1 0.0 0.084 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CCL98536.1 - 0.025 14.7 0.1 0.099 12.8 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 CCL98536.1 - 0.028 13.7 0.0 0.76 9.0 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CCL98536.1 - 0.028 14.5 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCL98536.1 - 0.03 15.1 0.1 0.16 12.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCL98536.1 - 0.045 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.11 CCL98538.1 - 7.1e-37 126.9 47.3 7.1e-37 126.9 32.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCL98538.1 - 1.2e-20 73.2 12.9 1.2e-20 73.2 8.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCL98538.1 - 7.6e-17 61.0 14.5 7.6e-17 61.0 10.0 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Xpo1 PF08389.7 CCL98539.1 - 3.8e-05 23.6 0.1 0.00073 19.4 0.0 3.1 2 1 0 2 2 2 1 Exportin 1-like protein ParcG PF10274.4 CCL98539.1 - 0.00018 21.4 0.2 0.093 12.6 0.0 3.3 3 0 0 3 3 3 1 Parkin co-regulated protein Adaptin_N PF01602.15 CCL98539.1 - 0.00053 18.4 0.4 0.031 12.6 0.0 2.3 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 CCL98539.1 - 0.0011 19.1 1.8 0.022 15.0 0.1 3.7 2 2 0 2 2 2 1 HEAT repeats CAS_CSE1 PF03378.10 CCL98539.1 - 0.046 12.0 0.0 0.2 9.9 0.0 2.0 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus MOR2-PAG1_C PF14225.1 CCL98539.1 - 0.058 13.1 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Cell morphogenesis C-terminal HEAT PF02985.17 CCL98539.1 - 0.11 12.6 1.6 1.9 8.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat TRI5 PF06330.6 CCL98540.1 - 3.7e-10 39.0 0.0 5.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) TRI5 PF06330.6 CCL98541.1 - 1.7e-14 53.2 0.2 2.2e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) TRI5 PF06330.6 CCL98542.1 - 2.1e-17 62.8 0.0 2.6e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.17 CCL98543.1 - 6.1e-39 133.8 0.0 3.2e-38 131.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Dus PF01207.12 CCL98544.1 - 5.7e-46 156.7 0.0 7.4e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) F-box-like PF12937.2 CCL98546.1 - 5.8e-07 29.1 0.1 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like Pyridox_oxase_2 PF12766.2 CCL98547.1 - 3.8e-20 72.0 0.0 6.7e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 CCL98547.1 - 2.4e-05 24.2 0.0 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TRI5 PF06330.6 CCL98549.1 - 4.4e-13 48.6 0.1 5.3e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) HpcH_HpaI PF03328.9 CCL98551.1 - 1.9e-32 111.9 0.0 2.2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 CCL98551.1 - 0.041 13.1 0.0 3.2 6.8 0.1 2.8 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase PK PF00224.16 CCL98551.1 - 0.076 11.6 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Pyridox_oxase_2 PF12766.2 CCL98552.1 - 2.1e-21 76.1 0.0 8e-21 74.2 0.0 1.9 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 CCL98552.1 - 9.2e-09 35.2 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PX PF00787.19 CCL98553.1 - 0.00043 20.0 0.0 0.00086 19.0 0.0 1.4 1 0 0 1 1 1 1 PX domain Trypan_PARP PF05887.6 CCL98554.1 - 4.4 7.1 21.6 0.16 11.7 7.8 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) BTB PF00651.26 CCL98555.1 - 5.1e-06 26.4 0.0 9.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4590 PF15257.1 CCL98555.1 - 0.04 13.7 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) Glyoxalase_3 PF13468.1 CCL98556.1 - 0.0034 17.3 0.1 0.0055 16.6 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain LRR_4 PF12799.2 CCL98558.1 - 3.9e-11 42.3 2.0 1.4e-09 37.3 0.4 3.2 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCL98558.1 - 2e-07 30.6 0.8 6.9e-07 28.9 0.4 2.0 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CCL98558.1 - 0.00016 21.2 0.2 2.7 8.3 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CCL98558.1 - 0.0004 20.1 1.8 1.4 9.4 0.1 3.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CCL98558.1 - 0.25 11.4 0.7 29 5.1 0.1 2.9 3 0 0 3 3 3 0 Leucine Rich repeat Glyco_hydro_16 PF00722.16 CCL98559.1 - 4.8e-34 117.2 0.2 6.2e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.27 CCL98560.1 - 1.4e-12 46.9 16.7 4.3e-06 26.4 0.1 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat F-box-like PF12937.2 CCL98561.1 - 1.7e-10 40.4 1.0 6.2e-10 38.6 0.1 2.5 3 0 0 3 3 3 1 F-box-like LRR_7 PF13504.1 CCL98561.1 - 0.21 11.9 2.6 67 4.3 0.1 4.3 3 1 0 3 3 3 0 Leucine rich repeat Abhydrolase_4 PF08386.5 CCL98563.1 - 9.5e-20 70.4 0.0 1.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 CCL98563.1 - 3.3e-12 46.4 0.0 9.5e-11 41.6 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCL98563.1 - 2.7e-10 40.5 0.1 2.2e-09 37.5 0.0 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCL98563.1 - 0.00018 21.2 0.0 0.0042 16.8 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family S1-P1_nuclease PF02265.11 CCL98564.1 - 4.1e-43 147.8 0.0 1.1e-38 133.2 0.0 3.0 3 0 0 3 3 3 3 S1/P1 Nuclease Metallophos PF00149.23 CCL98565.1 - 4e-07 29.6 0.0 6.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCL98565.1 - 6.9e-07 29.2 0.2 3e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L23 PF00276.15 CCL98566.1 - 1.4e-09 37.7 0.0 2.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF1977 PF09320.6 CCL98566.1 - 0.051 13.8 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) Rhomboid PF01694.17 CCL98567.1 - 4.6e-10 39.6 5.0 1e-08 35.3 3.5 2.6 1 1 0 1 1 1 1 Rhomboid family DUF1858 PF08984.6 CCL98567.1 - 0.17 11.5 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) Fer4_7 PF12838.2 CCL98570.1 - 2.4e-06 27.8 1.0 4.3e-06 27.0 0.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.22 CCL98570.1 - 3.9e-05 23.0 5.0 3.9e-05 23.0 3.5 1.8 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 CCL98570.1 - 5.6e-05 22.9 0.4 0.00012 21.8 0.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCL98570.1 - 0.00013 21.6 3.3 0.00027 20.6 2.3 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 CCL98570.1 - 0.00014 22.4 1.7 0.00024 21.7 1.0 1.5 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 CCL98570.1 - 0.00044 20.2 0.8 0.00085 19.3 0.5 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CCL98570.1 - 0.00053 20.2 13.0 0.0061 16.7 1.3 1.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 CCL98570.1 - 0.00064 20.0 0.9 0.0012 19.0 0.5 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.2 CCL98570.1 - 0.00074 19.6 3.0 0.00074 19.6 2.1 1.6 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_6 PF12837.2 CCL98570.1 - 0.0016 18.2 5.2 0.0016 18.2 3.6 1.6 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_2 PF12797.2 CCL98570.1 - 0.0033 17.2 4.8 0.0069 16.2 3.3 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_18 PF13746.1 CCL98570.1 - 0.024 15.0 2.5 0.026 14.9 0.7 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.5 CCL98570.1 - 0.028 14.5 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Fer4_15 PF13459.1 CCL98570.1 - 0.034 14.6 0.6 0.1 13.1 0.4 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_13 PF13370.1 CCL98570.1 - 0.21 11.9 5.7 0.38 11.1 3.2 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Prefoldin_2 PF01920.15 CCL98571.1 - 1.8e-24 85.5 1.6 2.2e-24 85.2 1.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 CCL98571.1 - 0.0034 17.0 2.0 0.0036 16.9 0.5 1.6 2 0 0 2 2 2 1 DASH complex subunit Dad3 TelA PF05816.6 CCL98571.1 - 0.017 13.8 3.7 1.7 7.3 0.0 2.0 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Syntaxin-6_N PF09177.6 CCL98571.1 - 0.02 15.2 2.3 0.03 14.7 0.6 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Prefoldin PF02996.12 CCL98571.1 - 0.034 13.8 3.5 1.4 8.5 2.4 2.2 1 1 0 1 1 1 0 Prefoldin subunit TBPIP PF07106.8 CCL98571.1 - 0.035 13.6 2.4 0.14 11.6 0.5 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 CCL98571.1 - 0.042 13.0 2.7 0.51 9.4 0.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_32 PF13654.1 CCL98571.1 - 0.054 12.1 0.7 0.069 11.8 0.5 1.2 1 0 0 1 1 1 0 AAA domain Spc24 PF08286.6 CCL98571.1 - 0.073 12.7 2.8 0.078 12.6 0.8 1.7 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 DASH_Dad2 PF08654.5 CCL98571.1 - 0.1 12.6 0.4 0.34 10.9 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad2 Borrelia_lipo_1 PF05714.6 CCL98571.1 - 0.11 11.6 1.5 6.5 5.7 0.1 2.1 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF1451 PF07295.6 CCL98571.1 - 0.13 12.0 1.2 0.16 11.7 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) ATG16 PF08614.6 CCL98571.1 - 0.2 11.4 3.7 0.14 11.9 1.2 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DASH_Spc34 PF08657.5 CCL98571.1 - 0.22 11.1 4.1 1.7 8.2 1.0 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 DivIC PF04977.10 CCL98571.1 - 0.29 10.6 2.9 0.18 11.2 0.4 1.8 2 0 0 2 2 2 0 Septum formation initiator DegS PF05384.6 CCL98571.1 - 0.3 10.2 2.3 9.2 5.4 0.1 2.1 2 0 0 2 2 2 0 Sensor protein DegS IncA PF04156.9 CCL98571.1 - 0.36 10.4 4.0 0.96 9.0 2.8 1.7 1 1 0 1 1 1 0 IncA protein Tho2 PF11262.3 CCL98571.1 - 0.36 9.8 1.7 0.72 8.8 0.3 1.8 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ADIP PF11559.3 CCL98571.1 - 3 7.7 6.1 2 8.2 2.4 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 CCL98571.1 - 3.7 7.3 7.1 2.3 7.9 0.9 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper CAP PF00188.21 CCL98572.1 - 6.6e-12 46.0 1.0 6.6e-12 46.0 0.7 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ATP-synt_10 PF05176.9 CCL98573.1 - 0.15 11.2 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 ATP10 protein TPR_11 PF13414.1 CCL98574.1 - 2.5e-12 46.2 0.2 3.6e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 TPR repeat SET PF00856.23 CCL98574.1 - 1.3e-11 45.0 0.0 1.2e-10 41.9 0.0 2.4 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.12 CCL98574.1 - 0.0017 18.1 4.8 0.25 11.3 0.7 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCL98574.1 - 0.0022 18.4 1.0 0.032 14.8 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCL98574.1 - 0.0024 18.1 0.1 0.48 10.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat YfiO PF13525.1 CCL98574.1 - 0.0038 16.7 0.1 0.0083 15.6 0.1 1.5 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_1 PF00515.23 CCL98574.1 - 0.034 13.7 5.7 0.46 10.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCL98574.1 - 0.052 13.7 0.6 0.35 11.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCL98574.1 - 0.069 13.8 1.5 0.39 11.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat EutB PF06751.6 CCL98574.1 - 0.12 10.7 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) DNA_mis_repair PF01119.14 CCL98575.1 - 3.1e-15 55.6 0.0 9.9e-07 28.2 0.0 2.3 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCL98575.1 - 3.8e-09 36.3 0.1 1.1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 CCL98575.1 - 7.6e-06 25.5 0.2 0.00015 21.3 0.0 2.7 3 0 0 3 3 3 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 CCL98575.1 - 3.3e-05 23.5 0.0 7.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hist_deacetyl PF00850.14 CCL98576.1 - 1.1e-76 258.1 0.0 1.5e-76 257.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain WD40 PF00400.27 CCL98577.1 - 1.1e-152 491.0 83.8 8.5e-13 47.6 0.5 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat PQQ_3 PF13570.1 CCL98577.1 - 2.1e-16 59.5 35.7 0.65 10.3 0.1 13.0 10 3 3 13 13 13 7 PQQ-like domain PQQ_2 PF13360.1 CCL98577.1 - 5.7e-11 42.3 28.9 5.3e-05 22.7 5.6 4.9 1 1 3 4 4 4 4 PQQ-like domain PD40 PF07676.7 CCL98577.1 - 7.9e-08 31.8 1.5 8.6 6.1 0.0 10.0 13 0 0 13 13 13 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 CCL98577.1 - 8.9e-08 30.7 38.0 0.0065 14.6 0.2 9.3 2 2 5 9 9 9 5 Nucleoporin Nup120/160 NACHT PF05729.7 CCL98577.1 - 6.9e-06 25.8 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PQQ PF01011.16 CCL98577.1 - 3.7e-05 23.0 10.7 2.7 7.6 0.0 6.5 7 0 0 7 7 7 2 PQQ enzyme repeat Cytochrom_D1 PF02239.11 CCL98577.1 - 5.4e-05 21.6 28.4 0.061 11.6 0.8 6.2 2 1 3 6 6 6 5 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CCL98577.1 - 0.0015 17.3 37.7 2.5 6.7 3.6 7.9 1 1 2 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 CCL98577.1 - 0.014 13.6 1.8 7 4.7 0.0 5.4 4 1 4 9 9 9 0 Protein of unknown function (DUF3312) AAA_16 PF13191.1 CCL98577.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 CCL98577.1 - 0.061 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.15 CCL98577.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase SBDS PF01172.13 CCL98578.1 - 9.5e-13 47.7 0.4 8.8e-12 44.6 0.2 2.0 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF4471 PF14740.1 CCL98578.1 - 3e-05 23.3 0.0 4.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) AvrRpt-cleavage PF05627.6 CCL98578.1 - 0.067 12.2 0.1 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr DAO PF01266.19 CCL98579.1 - 1.6e-34 119.4 3.0 2e-33 115.8 2.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCL98579.1 - 0.00086 19.2 0.1 0.0024 17.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCL98579.1 - 0.051 13.4 0.1 2.5 7.9 0.0 2.7 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCL98579.1 - 0.065 13.6 0.0 0.67 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CCL98579.1 - 0.08 12.5 5.2 0.028 14.0 1.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Isochorismatase PF00857.15 CCL98580.1 - 5.4e-24 85.0 0.0 8.3e-24 84.4 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family DUF3663 PF12404.3 CCL98580.1 - 0.11 12.2 0.0 14 5.5 0.1 2.4 2 0 0 2 2 2 0 Peptidase AFG1_ATPase PF03969.11 CCL98581.1 - 3e-91 305.9 0.0 1.9e-87 293.4 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 CCL98581.1 - 0.001 19.0 0.4 0.47 10.4 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CCL98581.1 - 0.0011 19.1 0.0 0.0049 17.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 CCL98581.1 - 0.0087 16.2 0.0 0.047 13.9 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 CCL98581.1 - 0.019 14.6 0.6 0.15 11.6 0.0 2.3 2 1 0 2 2 2 0 Bacterial dnaA protein NACHT PF05729.7 CCL98581.1 - 0.024 14.3 0.0 0.058 13.0 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 CCL98581.1 - 0.15 11.7 0.0 10 5.7 0.0 2.8 2 2 0 2 2 2 0 Archaeal ATPase Glyco_hydro_53 PF07745.8 CCL98582.1 - 3.9e-79 265.8 0.0 4.4e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 PRP21_like_P PF12230.3 CCL98583.1 - 0.00059 19.4 0.5 0.038 13.5 0.3 2.4 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein zf-ribbon_3 PF13248.1 CCL98583.1 - 0.0026 16.9 2.3 0.62 9.3 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon domain FYDLN_acid PF09538.5 CCL98583.1 - 0.01 16.3 0.7 0.01 16.3 0.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-dskA_traR PF01258.12 CCL98583.1 - 0.018 14.7 1.5 0.38 10.5 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Rad50_zn_hook PF04423.9 CCL98583.1 - 0.066 12.6 3.4 5.8 6.4 0.3 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif UPF0547 PF10571.4 CCL98583.1 - 0.072 12.8 6.9 0.86 9.3 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 CCL98583.1 - 0.076 12.5 0.7 11 5.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 CCL98583.1 - 0.12 12.5 2.4 3.3 7.9 0.0 2.7 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding T4_baseplate PF12322.3 CCL98583.1 - 0.14 11.4 0.1 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 T4 bacteriophage base plate protein DUF2116 PF09889.4 CCL98583.1 - 0.25 11.1 1.7 4.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DNA_ligase_ZBD PF03119.11 CCL98583.1 - 1.2 8.9 8.5 7.5 6.3 0.7 2.9 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Tom7 PF08038.7 CCL98584.1 - 7.8e-18 63.6 0.7 9e-18 63.4 0.5 1.1 1 0 0 1 1 1 1 TOM7 family JAB PF01398.16 CCL98585.1 - 8.8e-21 73.7 0.1 1.6e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CCL98585.1 - 1.3e-10 41.3 0.0 2.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UreF PF01730.11 CCL98586.1 - 3e-07 30.6 0.0 9.3e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 UreF Vac14_Fig4_bd PF11916.3 CCL98587.1 - 8.3e-82 272.7 5.2 1.4e-81 271.9 3.6 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CCL98587.1 - 3.1e-40 136.4 0.1 5e-37 126.2 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CCL98587.1 - 4.8e-11 41.7 2.0 0.00057 19.7 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 CCL98587.1 - 6.2e-05 23.3 0.4 0.87 10.1 0.0 5.4 5 1 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 CCL98587.1 - 0.021 14.6 3.4 0.98 9.2 0.0 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF2458 PF10454.4 CCL98587.1 - 0.022 14.6 0.4 0.055 13.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) ParcG PF10274.4 CCL98587.1 - 0.024 14.5 0.9 1 9.2 0.0 3.1 3 0 0 3 3 3 0 Parkin co-regulated protein DUF1546 PF07571.8 CCL98587.1 - 0.07 13.2 0.0 0.78 9.8 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1546) Arm PF00514.18 CCL98587.1 - 0.14 12.0 2.2 2.5 8.0 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Y_phosphatase3 PF13350.1 CCL98588.1 - 8.3e-48 162.7 0.0 1.2e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CCL98588.1 - 3.7e-13 49.3 0.1 8.7e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region PTPlike_phytase PF14566.1 CCL98588.1 - 0.0096 15.9 0.0 0.023 14.7 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 CCL98588.1 - 0.032 13.6 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCL98588.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MCM PF00493.18 CCL98589.1 - 4.7e-137 456.2 0.4 7.8e-137 455.5 0.2 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCL98589.1 - 6.9e-24 84.6 0.0 1.5e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCL98589.1 - 3.9e-07 29.4 0.0 3.8e-06 26.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCL98589.1 - 0.0023 17.5 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCL98589.1 - 0.0031 17.0 0.0 0.0072 15.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 CCL98589.1 - 0.021 14.5 0.0 0.074 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Fungal_trans PF04082.13 CCL98590.1 - 2.7e-13 49.4 1.0 3.2e-13 49.1 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mad3_BUB1_I PF08311.7 CCL98590.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 F-box PF00646.28 CCL98591.1 - 0.00013 21.4 0.2 0.0085 15.7 0.0 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 CCL98591.1 - 0.0015 18.1 0.1 0.0048 16.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like ELMO_CED12 PF04727.8 CCL98594.1 - 1.6e-29 102.6 0.1 2.9e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 CCL98594.1 - 7.3e-15 55.0 0.4 4.2e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) MTHFR PF02219.12 CCL98595.1 - 2e-104 348.7 0.0 3.1e-104 348.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PseudoU_synth_1 PF01416.15 CCL98596.1 - 5e-15 55.8 0.0 3.1e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase RNA_pol_Rpb4 PF03874.11 CCL98598.1 - 5.5e-19 68.3 0.2 7e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Aa_trans PF01490.13 CCL98599.1 - 3.4e-81 272.8 27.6 3.8e-81 272.6 19.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CCL98599.1 - 0.00078 18.3 22.9 0.00078 18.3 15.9 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SUZ PF12752.2 CCL98600.1 - 1.8e-14 54.0 1.4 1.8e-14 54.0 1.0 4.9 4 0 0 4 4 4 1 SUZ domain R3H PF01424.17 CCL98600.1 - 4.2e-05 23.1 0.1 0.00012 21.7 0.1 1.7 1 0 0 1 1 1 1 R3H domain DUF202 PF02656.10 CCL98602.1 - 3.5e-05 23.9 0.2 0.00017 21.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Asp PF00026.18 CCL98604.1 - 1.1e-24 87.2 0.1 1.6e-23 83.4 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCL98604.1 - 0.086 13.3 1.0 0.39 11.2 0.7 2.2 1 0 0 1 1 1 0 Aspartyl protease MBT PF02820.13 CCL98604.1 - 0.16 11.8 0.9 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 mbt repeat FGGY_C PF02782.11 CCL98605.1 - 1.4e-20 73.7 0.0 3e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCL98605.1 - 1.2e-11 44.3 0.0 7.4e-05 22.1 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cytochrom_B562 PF07361.6 CCL98606.1 - 0.021 15.2 3.7 0.038 14.3 1.0 2.4 2 0 0 2 2 2 0 Cytochrome b562 Spc7 PF08317.6 CCL98606.1 - 1.2 7.7 11.1 0.7 8.4 3.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein THOC7 PF05615.8 CCL98606.1 - 2 8.6 13.4 0.58 10.4 6.1 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 TMF_DNA_bd PF12329.3 CCL98606.1 - 2.9 7.7 10.9 0.12 12.2 1.7 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3391 PF11871.3 CCL98606.1 - 6.1 7.0 9.3 1 9.5 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) AAA_13 PF13166.1 CCL98606.1 - 8.5 4.6 10.2 16 3.7 7.1 1.4 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 CCL98608.1 - 8.6e-61 205.8 1.0 2.3e-46 158.4 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CCL98608.1 - 5.7e-18 65.2 0.0 9.7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCL98608.1 - 1.1e-05 25.6 0.0 2.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCL98608.1 - 1.5e-05 24.6 0.1 3.6e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 CCL98608.1 - 4.7e-05 21.3 1.8 0.00016 19.6 0.0 2.2 3 0 0 3 3 3 1 Helicase UvrD_C_2 PF13538.1 CCL98608.1 - 9.8e-05 22.4 0.0 0.00036 20.6 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 CCL98608.1 - 0.00099 19.1 0.1 0.003 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 CCL98608.1 - 0.0014 18.1 0.3 2.3 7.6 0.1 3.2 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CCL98608.1 - 0.0022 17.2 0.0 0.0069 15.6 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein TrwB_AAD_bind PF10412.4 CCL98608.1 - 0.0043 15.7 0.0 0.0072 14.9 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 CCL98608.1 - 0.0071 15.2 0.0 0.021 13.7 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.4 CCL98608.1 - 0.0073 15.3 0.0 0.02 13.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CCL98608.1 - 0.012 15.0 0.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 CCL98608.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CCL98608.1 - 0.036 13.2 0.1 0.067 12.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 CCL98608.1 - 0.038 14.1 0.2 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 CCL98608.1 - 0.042 12.5 0.0 0.071 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CCL98608.1 - 0.062 13.0 0.1 7.8 6.1 0.0 2.4 2 0 0 2 2 2 0 NTPase UvrD-helicase PF00580.16 CCL98608.1 - 0.1 11.8 0.2 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Pkinase PF00069.20 CCL98609.1 - 8.2e-73 244.7 0.0 1.3e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98609.1 - 6.4e-49 166.3 0.0 1e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCL98609.1 - 2.9e-22 78.8 1.4 7.9e-22 77.4 0.1 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CCL98609.1 - 0.00014 20.9 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCL98609.1 - 0.015 15.0 1.7 0.097 12.3 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 CCL98609.1 - 0.024 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 CCL98609.1 - 0.044 13.0 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 DSHCT (NUC185) domain TAN PF11640.3 CCL98610.1 - 5.6e-28 97.6 0.0 2.7e-27 95.4 0.0 2.2 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair PI3_PI4_kinase PF00454.22 CCL98610.1 - 2.6e-21 76.1 0.0 3.8e-11 42.9 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CCL98610.1 - 3.6e-07 29.4 0.2 2.3e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 FATC domain Rad9 PF04139.8 CCL98611.1 - 1.1e-50 172.1 0.0 1.5e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Rad9 Coatomer_E PF04733.9 CCL98612.1 - 8.5e-40 136.7 0.0 9.9e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.12 CCL98612.1 - 0.0028 17.4 0.0 10 6.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3046 PF11248.3 CCL98612.1 - 0.019 14.8 0.2 0.5 10.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) TPR_9 PF13371.1 CCL98612.1 - 0.02 14.7 2.7 0.054 13.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCL98612.1 - 0.07 12.9 0.0 7.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCL98612.1 - 0.51 10.7 0.1 0.51 10.7 0.1 3.4 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCL98612.1 - 1.6 9.6 10.4 0.41 11.3 0.4 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat An_peroxidase PF03098.10 CCL98613.1 - 1.7e-79 267.6 0.0 2.3e-77 260.5 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 CCL98613.1 - 3.9e-05 22.3 0.0 8.8e-05 21.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 zf-CSL PF05207.8 CCL98614.1 - 2.1e-14 52.7 0.9 3.8e-14 51.9 0.6 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 CCL98614.1 - 6.5e-14 51.4 0.1 1e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF914 PF06027.7 CCL98615.1 - 1.8e-104 349.2 4.8 2.2e-104 348.9 3.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CCL98615.1 - 0.0029 16.5 2.8 0.0046 15.9 2.0 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCL98615.1 - 0.089 12.4 9.2 0.88 9.2 0.3 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF4131 PF13567.1 CCL98615.1 - 1.9 7.8 10.8 2 7.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) EamA PF00892.15 CCL98615.1 - 7.1 6.6 25.3 8.7 6.4 4.0 3.7 2 1 2 4 4 4 0 EamA-like transporter family DUF4366 PF14283.1 CCL98616.1 - 0.011 15.1 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CDC45 PF02724.9 CCL98616.1 - 0.27 9.2 4.4 0.26 9.2 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CCL98616.1 - 1.3 7.4 7.7 1.5 7.2 5.4 1.0 1 0 0 1 1 1 0 Daxx Family RNA_pol_3_Rpc31 PF11705.3 CCL98616.1 - 7.8 6.3 17.9 10 5.9 12.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PS_Dcarbxylase PF02666.10 CCL98617.1 - 5.5e-53 179.2 0.0 8.9e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CCL98617.1 - 1.4e-31 108.1 0.1 8.8e-15 54.3 0.1 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 CCL98617.1 - 0.00063 19.8 0.2 0.0013 18.7 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair CEP76-C2 PF15627.1 CCL98617.1 - 0.04 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain TBPIP PF07106.8 CCL98619.1 - 1.1e-32 112.9 0.0 1.3e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomodulin PF03250.9 CCL98619.1 - 0.02 14.4 0.2 0.035 13.6 0.2 1.4 1 0 0 1 1 1 0 Tropomodulin HALZ PF02183.13 CCL98619.1 - 0.033 13.9 1.2 0.068 12.8 0.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF972 PF06156.8 CCL98619.1 - 0.04 14.2 0.3 0.073 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 CCL98619.1 - 0.055 12.9 2.6 0.24 10.9 1.8 2.1 1 1 0 1 1 1 0 Septum formation initiator DUF812 PF05667.6 CCL98619.1 - 0.083 11.3 1.8 0.1 11.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_1 PF00170.16 CCL98619.1 - 0.085 12.8 1.2 0.27 11.2 0.8 1.8 1 0 0 1 1 1 0 bZIP transcription factor Prefoldin_2 PF01920.15 CCL98619.1 - 0.098 12.4 1.1 0.2 11.4 0.7 1.5 1 0 0 1 1 1 0 Prefoldin subunit Mito_carr PF00153.22 CCL98620.1 - 3.7e-51 170.8 1.0 1.9e-19 69.1 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein ADH_zinc_N PF00107.21 CCL98621.1 - 1.1e-12 47.6 0.0 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCL98621.1 - 4.2e-11 42.5 0.0 6.6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CCL98621.1 - 0.0014 19.5 0.0 0.0024 18.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCL98622.1 - 6e-25 87.2 0.3 5e-13 48.7 0.0 2.5 2 1 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.7 CCL98622.1 - 1.3e-22 79.6 0.0 1.2e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain TRAM_LAG1_CLN8 PF03798.11 CCL98623.1 - 0.016 14.7 0.1 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 TLC domain T2SF PF00482.18 CCL98623.1 - 0.029 14.2 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF4233 PF14017.1 CCL98623.1 - 0.77 9.7 5.3 4 7.4 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Aldose_epim PF01263.15 CCL98625.1 - 9.5e-20 70.8 0.0 2.3e-18 66.3 0.0 2.2 1 1 0 1 1 1 1 Aldose 1-epimerase Aldo_ket_red PF00248.16 CCL98626.1 - 1.4e-14 53.5 0.0 2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2427 PF10348.4 CCL98627.1 - 1.2 8.7 7.6 1.1 8.8 2.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) p450 PF00067.17 CCL98628.1 - 6.3e-13 48.0 0.0 7.1e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCL98629.1 - 1.4e-34 119.4 0.0 2e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCL98630.1 - 1.8e-72 244.3 0.0 2.2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 CCL98631.1 - 1e-17 64.3 0.2 1.3e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 CCL98632.1 - 1.6e-68 231.3 0.0 2.3e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 CCL98633.1 - 4.6e-63 212.6 0.0 5.3e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 CCL98634.1 - 5.6e-47 160.3 0.0 9.8e-46 156.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 CCL98636.1 - 3.6e-27 95.1 0.0 2.7e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_23 PF13489.1 CCL98636.1 - 0.036 13.8 0.0 0.19 11.4 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 CCL98637.1 - 1.6e-37 128.9 0.0 2.4e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 CCL98637.1 - 1.4e-05 24.8 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCL98637.1 - 0.00054 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CCL98638.1 - 4.3e-36 124.3 0.0 6.5e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 CCL98638.1 - 1.2e-05 25.1 0.1 3.2e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCL98638.1 - 1.2e-05 25.8 0.0 2.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCL98638.1 - 0.0021 18.5 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCL98638.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CCL98638.1 - 0.055 13.0 0.0 0.15 11.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CCL98638.1 - 0.064 13.6 0.0 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Rrf2 PF02082.15 CCL98638.1 - 0.11 12.5 0.1 0.49 10.5 0.0 2.1 3 0 0 3 3 3 0 Transcriptional regulator UPF0014 PF03649.8 CCL98639.1 - 2e-34 118.9 12.7 2.6e-34 118.5 8.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.16 CCL98639.1 - 0.0027 17.4 4.7 0.0027 17.4 3.3 3.0 2 2 0 2 2 2 1 FtsX-like permease family GHMP_kinases_N PF00288.21 CCL98639.1 - 0.29 11.2 2.1 2.3 8.3 0.0 2.9 3 0 0 3 3 3 0 GHMP kinases N terminal domain NADH5_C PF06455.6 CCL98639.1 - 6 6.2 11.0 1.4 8.3 2.2 2.6 3 0 0 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus Sm_multidrug_ex PF06695.6 CCL98639.1 - 7.9 6.6 10.0 1.6 8.8 1.6 3.3 1 1 1 3 3 3 0 Putative small multi-drug export protein DnaJ PF00226.26 CCL98640.1 - 3e-09 36.4 1.4 3.6e-09 36.2 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain DUF4044 PF13253.1 CCL98640.1 - 0.00066 18.7 0.3 0.0012 17.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4044) Ala_racemase_N PF01168.15 CCL98641.1 - 4.1e-36 124.5 0.0 5.7e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DIOX_N PF14226.1 CCL98642.1 - 3.5e-16 59.7 0.0 5.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCL98642.1 - 1.7e-13 50.6 0.0 3.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_2 PF00891.13 CCL98643.1 - 5e-32 111.0 0.0 8.4e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 CCL98643.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCL98643.1 - 0.0045 17.5 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCL98643.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Aminotran_1_2 PF00155.16 CCL98644.1 - 3.9e-27 95.1 0.0 4.9e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CCL98644.1 - 8e-13 47.7 0.0 1.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Pkinase PF00069.20 CCL98645.1 - 7.9e-54 182.5 0.0 1.2e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98645.1 - 8.1e-30 103.7 0.1 1.3e-20 73.5 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 CCL98645.1 - 0.0025 17.6 2.6 0.024 14.3 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCL98645.1 - 0.0041 16.1 0.0 1.6 7.6 0.0 2.4 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.17 CCL98645.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family FliD_N PF02465.13 CCL98646.1 - 0.0016 18.7 8.5 0.012 15.9 2.2 3.1 2 1 0 2 2 2 1 Flagellar hook-associated protein 2 N-terminus FliJ PF02050.11 CCL98646.1 - 0.012 15.6 20.7 0.012 15.6 14.3 3.0 2 1 0 3 3 3 0 Flagellar FliJ protein Baculo_PEP_C PF04513.7 CCL98646.1 - 0.13 12.1 1.0 0.33 10.7 0.7 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pox_A_type_inc PF04508.7 CCL98646.1 - 0.28 11.0 10.2 4 7.4 1.1 4.0 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 CCL98646.1 - 0.37 9.9 4.8 1.1 8.3 3.4 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 CCL98646.1 - 0.56 7.9 13.9 1 7.1 9.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF330 PF03886.8 CCL98647.1 - 0.0025 17.2 0.1 0.0056 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF330) Pil1 PF13805.1 CCL98647.1 - 6.5 5.8 7.8 3.4 6.7 1.1 2.3 2 0 0 2 2 2 0 Eisosome component PIL1 Ribosomal_L1 PF00687.16 CCL98648.1 - 2.7e-54 183.8 1.4 3.4e-54 183.5 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family zf-CCCH PF00642.19 CCL98649.1 - 1e-05 25.0 1.8 1e-05 25.0 1.2 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CCL98650.1 - 2.7e-07 30.3 0.1 6.1e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCL98650.1 - 2.7e-06 26.8 0.1 5.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL98650.1 - 7.7e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCL98650.1 - 9.2e-05 22.1 0.1 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif bPH_6 PF10756.4 CCL98650.1 - 0.013 15.4 0.3 0.034 14.0 0.1 1.9 1 1 1 2 2 2 0 Bacterial PH domain zf-CCCH PF00642.19 CCL98650.1 - 0.37 10.5 5.7 0.67 9.6 4.0 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MDM31_MDM32 PF08118.6 CCL98653.1 - 1.4e-142 475.6 0.0 1.8e-142 475.3 0.0 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins MFS_1 PF07690.11 CCL98654.1 - 1.1e-28 100.0 38.0 4.8e-24 84.7 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCL98654.1 - 7e-05 21.2 0.8 0.00013 20.3 0.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 CCL98654.1 - 8.2e-05 21.2 5.1 8.2e-05 21.2 3.5 3.1 2 1 0 3 3 3 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 CCL98654.1 - 0.00022 19.7 26.6 0.00033 19.1 0.7 3.5 1 1 2 3 3 3 2 MFS/sugar transport protein Bax1-I PF01027.15 CCL98655.1 - 1.9e-49 168.0 26.3 2.2e-49 167.8 18.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2231 PF09990.4 CCL98657.1 - 0.17 12.2 4.9 0.11 12.8 0.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Pkinase PF00069.20 CCL98659.1 - 2.5e-42 144.8 0.0 3.9e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98659.1 - 3e-42 144.5 0.0 4.4e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCL98659.1 - 0.041 12.9 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCL98659.1 - 0.049 13.3 0.4 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family F-box PF00646.28 CCL98660.1 - 3.6e-08 32.8 1.2 1.1e-07 31.3 0.8 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCL98660.1 - 5.9e-08 32.3 0.5 1.4e-07 31.0 0.3 1.7 1 0 0 1 1 1 1 F-box-like Smr PF01713.16 CCL98661.1 - 5.3e-09 36.1 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Smr domain Glyco_hydro_92 PF07971.7 CCL98662.1 - 7.7e-119 397.5 2.4 9.6e-119 397.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 HlyIII PF03006.15 CCL98663.1 - 1.1e-37 129.6 21.7 1.5e-37 129.1 15.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related TFIID_20kDa PF03847.8 CCL98664.1 - 3.8e-28 97.5 0.3 7.1e-28 96.6 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 CCL98664.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PDZ_2 PF13180.1 CCL98664.1 - 0.047 13.5 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Histone PF00125.19 CCL98664.1 - 0.085 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 CCL98664.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit RHD3 PF05879.7 CCL98665.1 - 1.9e-246 819.6 1.7 1e-245 817.2 1.2 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 CCL98665.1 - 7.5e-07 28.4 0.2 1.6e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 CCL98665.1 - 9.9e-06 25.5 0.0 6.2e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCL98665.1 - 1.3e-05 25.0 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 CCL98665.1 - 0.00046 20.1 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CCL98665.1 - 0.00078 19.9 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein DUF3145 PF11343.3 CCL98665.1 - 0.012 14.9 0.4 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) Septin PF00735.13 CCL98665.1 - 0.039 12.9 0.1 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 CCL98665.1 - 0.16 11.1 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_polI_A14 PF08203.6 CCL98666.1 - 0.056 13.6 0.2 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 AFG1_ATPase PF03969.11 CCL98667.1 - 2.2e-48 164.9 0.0 2.7e-43 148.1 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase DUF1253 PF06862.7 CCL98669.1 - 4.3e-147 490.0 0.0 6.9e-147 489.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Topoisom_bac PF01131.15 CCL98670.1 - 2.2e-93 313.2 0.0 2.8e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CCL98670.1 - 1.1e-22 79.8 0.0 2.1e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.7 CCL98670.1 - 3.9e-12 45.8 8.0 9.6e-09 35.0 2.3 2.7 2 0 0 2 2 2 2 GRF zinc finger CPSF_A PF03178.10 CCL98671.1 - 2.2e-94 316.1 0.0 1.1e-93 313.9 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CCL98671.1 - 1.8e-70 237.5 0.0 2.9e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term OsmC PF02566.14 CCL98672.1 - 1.8e-12 47.3 0.0 2.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein OsmC PF02566.14 CCL98673.1 - 1.9e-12 47.2 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein SynMuv_product PF06047.6 CCL98674.1 - 1.6e-42 143.5 2.9 1.6e-42 143.5 2.0 2.5 3 0 0 3 3 3 1 Ras-induced vulval development antagonist MIP-T3 PF10243.4 CCL98674.1 - 0.00021 19.9 23.6 0.00021 19.9 16.4 2.2 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 FKBP_C PF00254.23 CCL98675.1 - 1.3e-33 114.9 0.0 1.6e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CHD5 PF04420.9 CCL98676.1 - 6e-21 74.7 0.4 8.7e-21 74.2 0.3 1.2 1 0 0 1 1 1 1 CHD5-like protein Ribosomal_L39 PF00832.15 CCL98676.1 - 6.4e-10 38.3 0.9 1.2e-09 37.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L39 protein Malate_synthase PF01274.17 CCL98677.1 - 4.6e-198 658.4 0.0 5.4e-198 658.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Pkinase PF00069.20 CCL98678.1 - 2.8e-20 72.5 0.0 9.4e-14 51.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98678.1 - 5.9e-13 48.4 0.0 1.6e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CCL98678.1 - 0.027 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family AMP-binding PF00501.23 CCL98680.1 - 2e-46 158.2 0.0 2.9e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCL98680.1 - 1.7e-05 25.6 0.0 4.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3895 PF13034.1 CCL98680.1 - 0.13 11.7 0.0 0.38 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) PALP PF00291.20 CCL98681.1 - 8.6e-51 172.9 0.7 8.6e-51 172.9 0.5 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 CCL98681.1 - 4.9e-24 84.8 1.0 1.2e-23 83.6 0.7 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCL98681.1 - 3.4e-18 65.3 0.1 2.5e-16 59.3 0.0 2.5 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CCL98681.1 - 0.011 15.4 1.0 0.035 13.8 0.2 2.0 2 0 0 2 2 2 0 Peptidase family M28 COG2 PF06148.6 CCL98683.1 - 1.7e-27 95.9 0.2 6.6e-27 93.9 0.2 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 CCL98683.1 - 3.9e-20 72.2 0.0 1.7e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Imm43 PF15602.1 CCL98683.1 - 0.032 14.2 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Immunity protein 43 Vps8 PF12816.2 CCL98684.1 - 4.5e-68 228.3 0.0 5.2e-65 218.3 0.0 2.5 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 CCL98684.1 - 2.8e-05 23.7 0.0 0.17 11.4 0.0 3.5 3 0 0 3 3 3 3 Region in Clathrin and VPS PHD PF00628.24 CCL98685.1 - 1.5e-08 34.1 9.0 2.6e-08 33.4 6.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCL98685.1 - 0.17 11.2 4.2 0.38 10.0 2.9 1.6 1 0 0 1 1 1 0 PHD-finger PALP PF00291.20 CCL98686.1 - 6e-66 222.7 0.0 6.7e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4597 PF15366.1 CCL98686.1 - 0.033 13.7 0.0 5 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Topoisom_I_N PF02919.10 CCL98687.1 - 9.2e-95 315.9 0.4 9.2e-95 315.9 0.3 3.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CCL98687.1 - 1.5e-91 305.6 3.9 3.6e-91 304.4 2.7 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CCL98687.1 - 1.2e-32 111.3 0.2 3.2e-32 110.0 0.1 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 CCL98687.1 - 0.39 9.8 2.3 0.3 10.2 0.0 2.0 3 0 0 3 3 3 0 RolB/RolC glucosidase family CTP_transf_1 PF01148.15 CCL98688.1 - 1.8e-76 257.2 23.1 2.3e-76 256.8 16.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family NARP1 PF12569.3 CCL98688.1 - 2.8 6.5 3.8 3.8 6.1 2.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ribosom_S12_S23 PF00164.20 CCL98689.1 - 3.1e-31 107.3 2.3 3.9e-20 71.5 0.4 2.3 2 0 0 2 2 2 2 Ribosomal protein S12/S23 BRO1 PF03097.13 CCL98689.1 - 2.5e-13 49.5 0.0 3.8e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain DUF3506 PF12014.3 CCL98690.1 - 2.8e-08 33.6 0.3 1.6e-06 27.9 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box PF00646.28 CCL98690.1 - 0.00029 20.3 0.3 0.00029 20.3 0.2 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CCL98690.1 - 0.024 14.3 2.0 0.048 13.3 1.4 1.5 1 0 0 1 1 1 0 F-box-like SKG6 PF08693.5 CCL98691.1 - 0.23 10.7 2.3 0.72 9.2 1.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 CCL98691.1 - 2.9 8.0 0.0 2.9 8.0 0.0 3.3 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Glutaredoxin PF00462.19 CCL98692.1 - 1.2e-12 47.6 0.0 1.6e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 CCL98692.1 - 0.003 17.7 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HAD_2 PF13419.1 CCL98693.1 - 1.2e-20 74.5 0.0 1.9e-20 73.8 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCL98693.1 - 3.3e-10 40.7 0.0 1.8e-09 38.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CCL98693.1 - 1.6e-05 24.7 0.0 0.033 14.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CCL98693.1 - 0.00093 19.4 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCL98693.1 - 0.0081 15.8 0.0 0.043 13.5 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Uma2 PF05685.7 CCL98693.1 - 0.031 13.6 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative restriction endonuclease CHZ PF09649.5 CCL98697.1 - 5.4e-05 22.3 15.6 0.0015 17.6 10.8 2.9 1 1 0 1 1 1 1 Histone chaperone domain CHZ FAM176 PF14851.1 CCL98697.1 - 0.00097 18.8 4.5 0.00097 18.8 3.1 1.3 1 1 0 1 1 1 1 FAM176 family DUF506 PF04720.7 CCL98697.1 - 0.037 13.6 1.0 0.043 13.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DUF3246 PF11596.3 CCL98697.1 - 0.083 12.1 5.6 0.12 11.6 3.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) SUKH-4 PF14435.1 CCL98697.1 - 0.2 11.3 5.2 0.34 10.6 3.6 1.3 1 0 0 1 1 1 0 SUKH-4 immunity protein Sporozoite_P67 PF05642.6 CCL98697.1 - 0.45 8.3 3.9 0.39 8.5 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 CCL98697.1 - 0.7 9.6 11.4 0.044 13.5 3.8 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal XAP5 PF04921.9 CCL98697.1 - 1.2 8.6 6.4 1.3 8.4 4.5 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Nucleo_P87 PF07267.6 CCL98697.1 - 1.6 7.2 5.5 2 7.0 3.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 CCL98697.1 - 2.6 5.9 7.1 2.5 6.0 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 CCL98697.1 - 2.8 7.4 20.2 0.08 12.4 8.6 1.9 2 0 0 2 2 2 0 Nucleoplasmin RRN3 PF05327.6 CCL98697.1 - 5.1 5.0 6.4 5 5.1 4.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ANAPC15 PF15243.1 CCL98697.1 - 6.6 6.8 20.3 0.92 9.6 8.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 AAA_17 PF13207.1 CCL98699.1 - 4.8e-07 30.6 0.0 8.2e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCL98699.1 - 2.2e-06 27.6 0.1 6.1e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 CCL98699.1 - 1.2e-05 25.2 0.0 0.00089 19.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.1 CCL98699.1 - 2.8e-05 24.4 0.0 0.0042 17.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCL98699.1 - 0.0024 17.9 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CCL98699.1 - 0.0042 16.8 0.3 0.016 14.9 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 CCL98699.1 - 0.0054 16.9 0.2 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CCL98699.1 - 0.0069 15.9 0.1 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCL98699.1 - 0.0098 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCL98699.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCL98699.1 - 0.013 15.6 0.0 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CCL98699.1 - 0.015 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 CCL98699.1 - 0.028 13.3 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE_Nter PF05157.10 CCL98699.1 - 0.037 14.0 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain PhoH PF02562.11 CCL98699.1 - 0.052 12.7 0.3 0.088 12.0 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 CCL98699.1 - 0.072 12.5 0.3 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein SRP54 PF00448.17 CCL98699.1 - 0.15 11.4 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 CCL98699.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Asp PF00026.18 CCL98700.1 - 1.6e-42 145.8 3.0 7e-38 130.6 0.4 2.4 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCL98700.1 - 4.9e-07 29.8 0.1 3.2e-06 27.2 0.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCL98700.1 - 0.041 14.3 4.9 2.5 8.6 0.8 4.2 3 1 0 3 3 3 0 Aspartyl protease TAXi_C PF14541.1 CCL98700.1 - 0.44 10.0 3.4 0.55 9.7 0.1 2.5 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Proteasome PF00227.21 CCL98701.1 - 1.9e-54 183.8 0.2 3.9e-54 182.8 0.1 1.5 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCL98701.1 - 2.1e-14 52.4 0.2 4.5e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ctr PF04145.10 CCL98702.1 - 5.8e-40 136.6 0.3 6.7e-40 136.4 0.2 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF4191 PF13829.1 CCL98702.1 - 0.21 10.6 1.2 0.4 9.7 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Rpr2 PF04032.11 CCL98703.1 - 1.3e-21 76.2 1.0 2.2e-21 75.5 0.7 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.11 CCL98703.1 - 0.021 14.7 1.3 0.039 13.9 0.9 1.4 1 1 0 1 1 1 0 Mut7-C RNAse domain Asp PF00026.18 CCL98704.1 - 6e-42 143.9 0.3 2.4e-41 142.0 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCL98704.1 - 1.4e-05 25.1 0.2 0.00038 20.4 0.2 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCL98704.1 - 0.1 13.0 0.3 0.79 10.2 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease Asp PF00026.18 CCL98705.1 - 4.2e-28 98.5 0.3 1.6e-27 96.5 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCL98705.1 - 0.006 16.5 0.0 0.05 13.5 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCL98705.1 - 0.0072 16.8 0.3 0.08 13.4 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease Med26 PF08711.6 CCL98706.1 - 0.0024 17.3 0.3 0.0037 16.7 0.2 1.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Turandot PF07240.6 CCL98706.1 - 0.061 12.8 0.1 0.089 12.2 0.1 1.3 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot LSM PF01423.17 CCL98707.1 - 2.7e-12 46.0 0.3 3.4e-12 45.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCL98707.1 - 0.053 13.4 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain E3_binding PF02817.12 CCL98707.1 - 0.068 12.8 0.3 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 e3 binding domain Voltage_CLC PF00654.15 CCL98708.1 - 8.2e-90 301.3 20.7 8.2e-90 301.3 14.3 1.9 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CCL98708.1 - 0.0051 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 CBS domain DUF663 PF04950.7 CCL98709.1 - 1e-92 310.2 0.0 1.9e-92 309.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCL98709.1 - 7.7e-19 67.0 0.0 1.9e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Spore_coat_CotO PF14153.1 CCL98709.1 - 2 7.8 11.8 0.35 10.2 2.5 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Vps53_N PF04100.7 CCL98710.1 - 4.1e-87 292.4 3.8 4.1e-87 292.4 2.6 1.8 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 CCL98710.1 - 9.7e-07 27.9 3.7 1.3e-06 27.5 1.7 1.8 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DAGK_prokar PF01219.14 CCL98710.1 - 0.026 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase Sec5 PF15469.1 CCL98710.1 - 0.073 12.7 7.4 0.062 13.0 2.7 2.5 2 1 0 2 2 2 0 Exocyst complex component Sec5 p450 PF00067.17 CCL98712.1 - 2.1e-60 204.5 0.0 5.7e-59 199.8 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 Autophagy_N PF03986.8 CCL98712.1 - 2.7e-44 150.4 0.0 5.5e-44 149.4 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CCL98712.1 - 1.8e-21 76.0 0.2 5e-21 74.6 0.1 1.9 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CCL98712.1 - 1e-11 43.7 3.2 2e-11 42.7 2.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-LYAR PF08790.6 CCL98713.1 - 8e-15 54.2 1.2 1.5e-14 53.3 0.8 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger peroxidase PF00141.18 CCL98714.1 - 6.2e-45 153.4 0.0 1.1e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase NOGCT PF08155.6 CCL98715.1 - 2.6e-29 100.6 1.3 2.6e-29 100.6 0.9 2.0 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 CCL98715.1 - 3.3e-29 100.5 0.2 6.3e-29 99.6 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CCL98715.1 - 2.2e-17 63.0 0.0 7e-17 61.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCL98715.1 - 2.2e-09 36.7 0.0 4.9e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCL98715.1 - 0.00066 20.1 0.0 0.003 18.0 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 CCL98715.1 - 0.0086 15.2 0.0 0.071 12.2 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCL98715.1 - 0.01 15.6 0.0 2.8 7.7 0.0 2.7 1 1 1 2 2 2 0 Dynamin family AIG1 PF04548.11 CCL98715.1 - 0.058 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 AIG1 family HPP PF04982.8 CCL98718.1 - 1e-37 128.5 7.9 1.7e-37 127.9 5.5 1.3 1 0 0 1 1 1 1 HPP family CoA_transf_3 PF02515.12 CCL98720.1 - 3.3e-37 127.5 0.0 1.5e-34 118.8 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Histone PF00125.19 CCL98721.1 - 6e-22 77.5 0.2 8.7e-22 77.0 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCL98721.1 - 3.4e-05 23.8 0.1 3.4e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCL98721.1 - 0.00024 21.3 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 CCL98721.1 - 0.059 13.8 0.4 0.081 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 CCL98721.1 - 0.088 12.1 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein RP-C PF03428.8 CCL98721.1 - 0.1 12.0 0.1 0.16 11.3 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain DUF3408 PF11888.3 CCL98721.1 - 0.94 9.4 4.2 1.5 8.7 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Histone PF00125.19 CCL98722.1 - 3.7e-26 91.0 0.0 4.7e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCL98722.1 - 2e-06 27.7 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HECT_2 PF09814.4 CCL98723.1 - 3.4e-32 111.5 0.0 5.3e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GRAB PF10375.4 CCL98724.1 - 2.7e-06 26.7 0.6 5.6e-06 25.8 0.4 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain LPP PF04728.8 CCL98724.1 - 0.00092 18.9 4.0 0.012 15.3 1.0 2.8 2 0 0 2 2 2 1 Lipoprotein leucine-zipper GRIP PF01465.15 CCL98724.1 - 0.023 14.2 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 GRIP domain CENP-F_leu_zip PF10473.4 CCL98724.1 - 0.19 11.6 48.6 0.037 13.8 11.4 4.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2562 PF10814.3 CCL98724.1 - 0.55 10.1 6.0 0.29 11.0 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) HrpA_pilin PF09589.5 CCL98724.1 - 0.56 10.6 8.4 0.55 10.6 3.1 2.9 1 1 1 2 2 2 0 HrpA pilus formation protein MAD PF05557.8 CCL98724.1 - 0.64 8.0 45.1 1.2 7.1 21.9 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein WEMBL PF05701.6 CCL98724.1 - 1 7.7 45.6 0.26 9.7 22.8 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light YfhO PF09586.5 CCL98724.1 - 1.4 6.8 2.7 1.7 6.5 1.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1054 PF06335.7 CCL98724.1 - 2.1 7.9 8.1 0.21 11.2 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1054) Peptidase_C37 PF05416.7 CCL98724.1 - 5.4 5.1 11.2 3.2 5.9 6.1 1.7 1 1 1 2 2 2 0 Southampton virus-type processing peptidase WD40 PF00400.27 CCL98725.1 - 2.6e-19 68.2 0.7 3.5e-06 26.6 0.0 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 CCL98725.1 - 0.0027 17.4 0.0 1.2 8.8 0.0 3.3 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Homoserine_dh PF00742.14 CCL98726.1 - 6.1e-46 156.3 0.0 7.8e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CCL98726.1 - 5e-18 65.6 0.0 1.1e-17 64.5 0.0 1.6 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CCL98726.1 - 0.001 19.3 0.0 0.023 15.0 0.0 2.7 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Histone PF00125.19 CCL98727.1 - 9.4e-23 80.1 0.3 1.6e-22 79.4 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCL98727.1 - 6.1e-06 26.1 0.1 6.1e-06 26.1 0.1 2.2 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCL98727.1 - 0.00025 21.2 0.0 0.00045 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.6 CCL98727.1 - 0.07 12.5 0.1 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DUF1018 PF06252.7 CCL98727.1 - 0.082 13.4 0.4 0.12 12.8 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) DUF601 PF04642.7 CCL98727.1 - 0.56 9.5 7.2 0.63 9.3 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Arabinose_bd PF12625.2 CCL98728.1 - 0.023 14.4 0.2 0.13 12.1 0.0 2.2 2 1 1 3 3 3 0 Arabinose-binding domain of AraC transcription regulator, N-term CTP_transf_1 PF01148.15 CCL98729.1 - 2.1e-11 43.9 10.5 2.1e-07 30.8 2.3 2.6 1 1 1 2 2 2 2 Cytidylyltransferase family Amidase PF01425.16 CCL98730.1 - 3.2e-57 194.3 0.0 1.3e-48 165.9 0.0 3.0 1 1 1 2 2 2 2 Amidase PGPGW PF09656.5 CCL98730.1 - 5.2 6.4 6.5 4.7 6.5 0.3 2.5 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) MFS_1 PF07690.11 CCL98733.1 - 4.7e-14 51.8 35.7 4.7e-14 51.8 24.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CCL98733.1 - 0.013 15.2 2.2 0.027 14.2 0.6 2.2 2 0 0 2 2 2 0 MFS_1 like family MFS_2 PF13347.1 CCL98734.1 - 1.6e-13 49.8 11.1 1.6e-13 49.8 7.7 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 CCL98734.1 - 1.1e-06 27.6 17.3 1.1e-06 27.6 12.0 3.0 3 1 0 3 3 3 2 Major Facilitator Superfamily DUF3619 PF12279.3 CCL98734.1 - 0.064 13.3 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) ETF_QO PF05187.8 CCL98735.1 - 7.1e-26 90.3 0.0 3.3e-19 68.9 0.0 2.4 2 0 0 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CCL98735.1 - 1.4e-09 37.3 0.1 4.5e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCL98735.1 - 2.8e-07 30.4 0.0 8e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCL98735.1 - 2.3e-06 26.7 0.9 1.6e-05 23.9 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 CCL98735.1 - 4.8e-05 23.1 0.1 0.0002 21.1 0.1 2.0 1 1 1 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCL98735.1 - 6e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCL98735.1 - 0.00013 21.1 0.1 0.0002 20.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CCL98735.1 - 0.00029 19.4 0.2 0.00044 18.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 CCL98735.1 - 0.00035 20.6 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCL98735.1 - 0.00078 18.6 0.2 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 CCL98735.1 - 0.0012 18.0 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCL98735.1 - 0.0012 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 CCL98735.1 - 0.016 13.8 0.1 0.031 12.9 0.1 1.5 1 1 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 CCL98735.1 - 0.11 12.9 0.1 2.7 8.4 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCL98735.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer2 PF00111.22 CCL98736.1 - 3.3e-11 42.7 0.1 5.6e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Sel1 PF08238.7 CCL98738.1 - 2.6e-18 66.0 20.1 3.8e-07 30.5 0.0 7.0 7 0 0 7 7 7 5 Sel1 repeat TPR_14 PF13428.1 CCL98738.1 - 0.021 15.4 1.6 9.3 7.1 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCL98738.1 - 3.8 7.2 6.3 1.4 8.6 0.3 2.8 3 0 0 3 3 3 0 TPR repeat ADH_N PF08240.7 CCL98739.1 - 3e-21 75.2 1.2 5.4e-21 74.3 0.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCL98739.1 - 2.6e-07 30.2 0.0 5.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.4 CCL98739.1 - 1.1 8.4 5.9 2.6 7.2 4.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region CAP_GLY PF01302.20 CCL98740.1 - 2.7e-09 36.5 0.5 3e-08 33.2 0.3 2.3 2 0 0 2 2 2 1 CAP-Gly domain BTB PF00651.26 CCL98740.1 - 2.8e-09 36.9 0.0 2.2e-08 34.0 0.0 2.5 2 1 0 3 3 3 1 BTB/POZ domain Hexapep PF00132.19 CCL98741.1 - 7.3e-07 28.4 16.8 0.0046 16.4 0.3 5.0 4 2 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Subtilosin_A PF11420.3 CCL98741.1 - 0.49 10.4 4.6 0.51 10.4 0.3 2.6 2 0 0 2 2 2 0 Bacteriocin subtilosin A Hexapep_2 PF14602.1 CCL98741.1 - 2.3 7.8 10.3 0.32 10.5 1.0 3.1 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Ribosomal_L16 PF00252.13 CCL98742.1 - 2.9e-34 117.7 0.0 3.6e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HCNGP PF07818.8 CCL98743.1 - 4.7e-19 68.2 0.0 7.1e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 HCNGP-like protein FAD_binding_8 PF08022.7 CCL98745.1 - 2e-13 50.0 0.0 3.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CCL98745.1 - 1.5e-09 37.9 0.0 1.7e-07 31.2 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CCL98745.1 - 2e-08 34.3 7.5 2e-08 34.3 5.2 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component PAS_9 PF13426.1 CCL98746.1 - 3.5e-31 107.6 0.0 2e-15 57.0 0.0 3.7 4 0 0 4 4 4 3 PAS domain PAS PF00989.19 CCL98746.1 - 7.9e-22 77.1 0.0 8.4e-07 28.7 0.0 4.5 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.6 CCL98746.1 - 2.3e-15 56.4 0.0 3e-08 33.6 0.0 4.6 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.5 CCL98746.1 - 2.5e-14 53.2 0.0 0.00057 19.8 0.0 4.5 4 0 0 4 4 4 3 PAS fold PAS_11 PF14598.1 CCL98746.1 - 1.7e-09 37.6 0.0 6e-08 32.6 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 CCL98746.1 - 0.00086 19.0 0.0 0.38 10.6 0.0 2.9 2 0 0 2 2 2 1 PAS domain F_bP_aldolase PF01116.15 CCL98747.1 - 5.2e-96 321.1 0.0 6.7e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II LSM PF01423.17 CCL98747.1 - 7.8e-12 44.5 0.2 1.7e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 LSM domain Torsin PF06309.6 CCL98747.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Torsin CPSase_L_D2 PF02786.12 CCL98747.1 - 0.12 11.6 0.5 0.53 9.5 0.3 1.9 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain BCDHK_Adom3 PF10436.4 CCL98748.1 - 5.3e-66 221.1 0.0 7.2e-66 220.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCL98748.1 - 2.5e-19 69.0 0.1 9.1e-19 67.2 0.0 2.0 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCL98748.1 - 0.0018 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 6PGD PF00393.14 CCL98749.1 - 5.8e-66 222.6 0.0 7.1e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CCL98749.1 - 6.6e-32 110.5 0.0 1.2e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 CCL98749.1 - 1.2e-06 28.2 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CCL98749.1 - 1.4e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 CCL98749.1 - 0.007 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 CCL98749.1 - 0.021 15.2 0.1 0.082 13.3 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 CCL98749.1 - 0.023 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CCL98749.1 - 0.038 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 CCL98749.1 - 0.089 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 CCL98749.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CCL98749.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pkinase PF00069.20 CCL98750.1 - 3.5e-41 141.0 0.3 3.8e-35 121.3 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98750.1 - 4.4e-18 65.3 0.2 8.7e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CCL98750.1 - 0.0011 18.0 0.3 0.0019 17.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCL98750.1 - 0.066 12.9 1.7 6 6.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CCL98750.1 - 0.072 12.0 0.1 0.15 10.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 CCL98750.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CBF PF03914.12 CCL98752.1 - 1.5e-39 135.1 2.0 3.6e-39 133.8 1.4 1.7 1 0 0 1 1 1 1 CBF/Mak21 family HEAT PF02985.17 CCL98752.1 - 0.0062 16.5 0.8 0.02 14.9 0.1 2.3 2 0 0 2 2 2 1 HEAT repeat EIF_2_alpha PF07541.7 CCL98753.1 - 1.3e-36 124.7 0.1 7.6e-36 122.3 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CCL98753.1 - 6e-13 48.6 0.8 1e-12 47.9 0.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain WD40 PF00400.27 CCL98754.1 - 3.1e-59 194.8 18.9 2.1e-10 40.0 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Tup_N PF08581.5 CCL98754.1 - 4.2e-19 68.5 1.6 1.1e-12 47.9 0.2 2.3 2 0 0 2 2 2 2 Tup N-terminal eIF2A PF08662.6 CCL98754.1 - 0.0018 18.0 0.0 0.61 9.7 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 CCL98754.1 - 0.0019 17.6 0.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 CCL98754.1 - 0.0021 16.8 0.1 6 5.4 0.0 3.2 1 1 0 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 CCL98754.1 - 0.0032 15.8 0.4 0.42 8.8 0.0 2.6 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.1 CCL98754.1 - 0.0048 16.0 0.1 10 5.1 0.0 3.5 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 CCL98754.1 - 0.033 13.5 3.0 5.6 6.3 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature HALZ PF02183.13 CCL98754.1 - 0.11 12.1 1.1 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Nup160 PF11715.3 CCL98754.1 - 0.13 10.3 0.2 0.76 7.8 0.0 2.3 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Bud13 PF09736.4 CCL98755.1 - 4.2e-46 156.7 10.6 4.2e-46 156.7 7.4 2.1 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex PPI_Ypi1 PF07491.6 CCL98755.1 - 8.3 6.1 7.0 0.74 9.4 0.8 2.4 3 0 0 3 3 3 0 Protein phosphatase inhibitor MR_MLE_C PF13378.1 CCL98757.1 - 6.1e-17 61.5 0.1 1.3e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 CCL98757.1 - 8.8e-13 48.5 0.0 2.6e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 CCL98757.1 - 8.1e-09 35.4 0.0 1.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 CCL98757.1 - 0.043 12.7 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Sec23_trunk PF04811.10 CCL98759.1 - 3.1e-46 157.7 0.0 5.1e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCL98759.1 - 3.3e-20 71.4 0.1 7.2e-20 70.3 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCL98759.1 - 6e-18 65.1 0.1 1.3e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCL98759.1 - 4.5e-14 51.7 3.5 9.8e-14 50.6 2.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCL98759.1 - 0.0051 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Bap31 PF05529.7 CCL98760.1 - 0.031 13.7 4.6 0.03 13.7 1.9 1.8 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4407 PF14362.1 CCL98760.1 - 0.042 12.7 7.8 0.06 12.3 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3440 PF11922.3 CCL98760.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3440) DivIC PF04977.10 CCL98760.1 - 0.075 12.5 7.4 0.45 10.0 2.0 2.8 2 1 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CCL98760.1 - 0.078 12.7 12.0 0.59 9.8 8.3 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.8 CCL98760.1 - 0.099 13.3 1.6 0.4 11.4 0.5 2.3 1 1 2 3 3 3 0 Occludin homology domain AAA_13 PF13166.1 CCL98760.1 - 0.11 11.0 1.2 0.14 10.5 0.8 1.1 1 0 0 1 1 1 0 AAA domain ERM PF00769.14 CCL98760.1 - 0.16 11.4 9.5 0.32 10.5 6.6 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Filament PF00038.16 CCL98760.1 - 0.23 10.9 12.2 2.9 7.2 7.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein APG6 PF04111.7 CCL98760.1 - 0.36 9.8 6.8 0.52 9.3 4.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 CCL98760.1 - 0.86 9.3 4.9 0.62 9.7 0.9 2.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 CCL98760.1 - 1 8.8 3.9 1.8 8.1 1.6 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2360 PF10152.4 CCL98760.1 - 4.2 7.6 6.2 22 5.2 0.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PDEase_I PF00233.14 CCL98761.1 - 7e-34 117.6 0.0 5.8e-27 94.9 0.0 3.1 3 0 0 3 3 3 3 3'5'-cyclic nucleotide phosphodiesterase zf-C2H2_4 PF13894.1 CCL98762.1 - 0.0038 17.4 0.7 2.7 8.5 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCL98762.1 - 0.025 14.9 0.4 4.4 7.8 0.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type COX16 PF14138.1 CCL98763.1 - 1.4e-27 95.6 0.0 1.7e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 RPN7 PF10602.4 CCL98764.1 - 6.1e-56 188.5 0.4 8.8e-56 188.0 0.3 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CCL98764.1 - 6.3e-17 61.8 0.2 1.6e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 PCI domain SAC3_GANP PF03399.11 CCL98764.1 - 0.0025 17.4 0.2 0.0041 16.6 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCL98764.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_15 PF13429.1 CCL98764.1 - 0.016 14.2 0.5 0.03 13.4 0.3 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCL98764.1 - 0.024 14.5 0.4 0.16 11.8 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCL98764.1 - 0.13 12.2 1.7 0.27 11.2 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PCI PF01399.22 CCL98765.1 - 1.5e-18 66.9 0.2 9.2e-18 64.4 0.1 2.4 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.1 CCL98765.1 - 8.6e-05 22.0 4.3 0.0081 15.8 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCL98765.1 - 0.00017 21.1 4.0 2.9 7.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat DDRGK PF09756.4 CCL98765.1 - 0.024 14.0 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 0 DDRGK domain Npa1 PF11707.3 CCL98765.1 - 0.026 13.5 0.2 0.17 10.8 0.0 2.0 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal Phage_GPO PF05929.6 CCL98765.1 - 0.047 12.9 0.1 0.15 11.3 0.0 1.8 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_2 PF07719.12 CCL98765.1 - 0.14 12.1 5.3 2.2 8.3 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCL98765.1 - 1.6 8.4 4.2 4.3 7.1 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCL98765.1 - 3 7.5 6.3 1.3 8.7 0.1 3.3 4 0 0 4 4 4 0 TPR repeat ESSS PF10183.4 CCL98766.1 - 0.12 12.7 0.1 0.44 10.9 0.1 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HDA2-3 PF11496.3 CCL98767.1 - 0.042 12.6 2.4 0.083 11.6 1.7 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 SbcD_C PF12320.3 CCL98767.1 - 0.06 13.3 3.4 0.12 12.3 2.3 1.5 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain AT_hook PF02178.14 CCL98767.1 - 0.26 11.0 5.8 0.71 9.7 4.0 1.8 1 0 0 1 1 1 0 AT hook motif Ino80_Iec3 PF14612.1 CCL98767.1 - 0.47 10.4 9.7 0.062 13.3 2.7 1.9 1 1 1 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling TBPIP PF07106.8 CCL98767.1 - 3 7.3 9.5 1.9 8.0 0.4 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cyclin PF08613.6 CCL98768.1 - 2.9e-10 40.7 0.0 5.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCL98768.1 - 1.7e-08 34.0 0.0 2.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3506 PF12014.3 CCL98769.1 - 1.9e-09 37.4 0.2 4e-07 29.9 0.0 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box PF00646.28 CCL98769.1 - 0.021 14.4 1.8 0.033 13.8 0.5 1.9 2 0 0 2 2 2 0 F-box domain Ral PF11058.3 CCL98769.1 - 0.086 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral F-box-like PF12937.2 CCL98769.1 - 0.75 9.5 4.4 0.59 9.9 0.7 2.5 3 0 0 3 3 3 0 F-box-like HAD PF12710.2 CCL98771.1 - 1.7e-14 54.4 0.1 9.9e-14 51.9 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCL98771.1 - 1.2e-13 51.9 0.4 2.2e-05 24.9 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCL98771.1 - 5.2e-13 48.5 0.8 8e-12 44.6 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CCL98771.1 - 1.5e-12 47.2 0.0 3.9e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCL98771.1 - 0.00056 19.5 0.8 0.0087 15.6 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IIGP PF05049.8 CCL98772.1 - 2.5e-08 33.1 0.0 5.8e-08 31.9 0.0 1.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) HrcA PF01628.16 CCL98772.1 - 0.00049 19.7 0.3 0.00077 19.1 0.2 1.3 1 0 0 1 1 1 1 HrcA protein C terminal domain KorB PF08535.5 CCL98772.1 - 0.057 13.5 0.3 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 KorB domain Nop16 PF09420.5 CCL98772.1 - 0.84 9.7 6.8 2.3 8.3 1.1 2.6 1 1 1 2 2 2 0 Ribosome biogenesis protein Nop16 PIN_4 PF13638.1 CCL98772.1 - 3.1 7.9 5.8 0.74 9.9 0.5 2.3 2 1 1 3 3 3 0 PIN domain Aminotran_1_2 PF00155.16 CCL98773.1 - 4.8e-32 111.3 0.0 6.2e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 CCL98773.1 - 6.5e-05 21.6 0.0 9.4e-05 21.1 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 CCL98773.1 - 0.033 12.4 0.0 0.045 12.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RNase_P_Rpp14 PF01900.14 CCL98774.1 - 6.7e-24 83.8 0.0 8.6e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Oxidored_molyb PF00174.14 CCL98775.1 - 5.8e-46 155.9 0.0 8.8e-46 155.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CCL98775.1 - 3.5e-20 71.9 0.6 6.8e-20 71.0 0.4 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Acetyltransf_7 PF13508.1 CCL98776.1 - 3e-07 30.5 0.0 5.4e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCL98776.1 - 2.5e-05 24.2 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCL98776.1 - 0.00035 20.2 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCL98776.1 - 0.00056 20.0 0.0 0.0016 18.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain CBM_5_12 PF02839.9 CCL98777.1 - 4.2e-08 32.6 15.4 1.1e-07 31.2 7.8 3.0 2 0 0 2 2 2 1 Carbohydrate binding domain DUF3439 PF11921.3 CCL98777.1 - 0.046 13.4 9.5 0.12 12.1 6.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.6 CCL98777.1 - 2.7 5.7 7.2 3.6 5.3 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4632 PF15451.1 CCL98778.1 - 0.019 14.9 0.4 0.037 13.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) bZIP_2 PF07716.10 CCL98779.1 - 0.0053 16.5 3.9 0.013 15.2 2.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.10 CCL98779.1 - 0.12 11.9 4.1 6.2 6.3 1.6 2.4 2 0 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.4 CCL98779.1 - 0.18 11.6 1.4 0.2 11.5 0.2 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CASP_C PF08172.7 CCL98779.1 - 0.35 9.8 3.6 0.59 9.1 2.5 1.3 1 0 0 1 1 1 0 CASP C terminal Cortex-I_coil PF09304.5 CCL98779.1 - 1.7 8.7 5.7 3.2 7.8 1.1 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil CRAL_TRIO PF00650.15 CCL98782.1 - 9.6e-30 103.1 0.0 2e-29 102.1 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCL98782.1 - 0.00015 21.8 0.1 0.0004 20.4 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCL98782.1 - 0.00068 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cpn60_TCP1 PF00118.19 CCL98783.1 - 1.6e-142 475.6 0.1 2e-142 475.2 0.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.23 CCL98783.1 - 2.6e-41 141.2 1.2 3.7e-41 140.7 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase eIF-1a PF01176.14 CCL98784.1 - 9.1e-29 98.6 0.1 1.3e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ank_2 PF12796.2 CCL98785.1 - 4.9e-11 42.8 0.0 2.1e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCL98785.1 - 0.00036 20.9 0.0 0.023 15.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCL98785.1 - 0.00046 19.8 0.0 3.9 7.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCL98785.1 - 0.00068 19.7 0.0 0.055 13.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCL98785.1 - 0.12 12.6 0.0 20 5.7 0.0 3.3 3 1 0 3 3 3 0 Ankyrin repeat Macro PF01661.16 CCL98786.1 - 9.7e-42 141.6 0.1 1.3e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Macro domain Sugar_tr PF00083.19 CCL98787.1 - 2.8e-80 270.0 12.3 3.8e-80 269.6 8.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 CCL98788.1 - 1.2e-65 221.2 0.0 1.9e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98788.1 - 4.1e-37 127.6 0.0 5.5e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCL98788.1 - 5.9e-09 35.2 0.0 1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCL98788.1 - 6.2e-05 22.8 0.5 9.8e-05 22.1 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCL98788.1 - 0.045 12.8 0.2 0.087 11.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CCL98788.1 - 0.062 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PKD_channel PF08016.7 CCL98789.1 - 9.7e-07 27.5 10.1 3.3e-05 22.5 1.5 2.2 1 1 1 2 2 2 2 Polycystin cation channel WD40 PF00400.27 CCL98790.1 - 0.00038 20.2 1.2 0.11 12.4 0.0 3.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoplasmin PF03066.10 CCL98790.1 - 0.068 12.6 0.7 0.14 11.6 0.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 CCL98790.1 - 0.32 10.5 1.6 0.48 10.0 1.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Glyco_trans_1_3 PF13528.1 CCL98791.1 - 6.4e-05 22.2 0.0 0.00023 20.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 1 NPR3 PF03666.8 CCL98792.1 - 6.3e-54 183.2 0.3 6.3e-54 183.2 0.2 2.3 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Epimerase PF01370.16 CCL98793.1 - 6.1e-22 78.2 0.0 8e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCL98793.1 - 4.2e-13 49.7 0.3 6.1e-13 49.1 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCL98793.1 - 1.2e-11 43.8 0.0 1.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CCL98793.1 - 1e-05 24.5 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 CCL98793.1 - 0.00011 21.5 0.1 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 CCL98793.1 - 0.00013 20.9 0.2 0.0066 15.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 CCL98793.1 - 0.0021 17.9 0.2 0.0033 17.3 0.1 1.4 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 CCL98793.1 - 0.0026 17.5 0.3 0.0046 16.7 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CCL98793.1 - 0.0051 15.8 0.2 0.0074 15.3 0.1 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 CCL98793.1 - 0.05 13.6 0.2 0.081 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Terpene_synth_C PF03936.11 CCL98795.1 - 1.6e-12 47.2 0.2 3.1e-12 46.2 0.1 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Orthoreo_P17 PF07272.6 CCL98795.1 - 0.077 12.7 0.2 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Orthoreovirus P17 protein WD40 PF00400.27 CCL98796.1 - 0.00014 21.6 2.0 0.001 18.8 0.0 3.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Aa_trans PF01490.13 CCL98797.1 - 5.5e-82 275.4 32.8 8.1e-82 274.8 22.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1908 PF08926.6 CCL98797.1 - 0.67 8.6 2.8 0.78 8.4 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) Acetyltransf_7 PF13508.1 CCL98798.1 - 9.6e-09 35.2 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCL98798.1 - 4e-07 29.9 0.0 6.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCL98798.1 - 0.0012 18.6 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 CCL98798.1 - 0.0024 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 CCL98798.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCL98798.1 - 0.0066 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCL98798.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCL98799.1 - 6.7e-08 32.5 0.0 1.8e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCL98799.1 - 4.6e-07 29.7 0.0 1.1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCL98799.1 - 6.7e-06 26.2 0.0 1.7e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCL98799.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CCL98799.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCL98799.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AhpC-TSA_2 PF13911.1 CCL98800.1 - 4.9e-17 61.8 0.0 9e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 CCL98800.1 - 0.00059 19.5 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCL98800.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Redoxin Gtr1_RagA PF04670.7 CCL98801.1 - 7.8e-53 178.9 0.1 1e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CCL98801.1 - 9.9e-05 21.6 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCL98801.1 - 0.00051 19.3 0.0 0.00089 18.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CCL98801.1 - 0.0015 18.4 0.2 0.0044 16.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 CCL98801.1 - 0.0015 18.9 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 CCL98801.1 - 0.0062 16.2 0.1 0.019 14.6 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 CCL98801.1 - 0.028 14.3 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.17 CCL98801.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ras family VTC PF09359.5 CCL98802.1 - 7.4e-92 307.3 0.0 2.1e-91 305.8 0.0 1.8 1 1 0 1 1 1 1 VTC domain SPX PF03105.14 CCL98802.1 - 2.9e-12 46.9 20.2 5.7e-12 45.9 8.2 3.3 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 CCL98802.1 - 1.1e-09 38.3 3.1 2.5e-09 37.2 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Herpes_UL25 PF01499.11 CCL98802.1 - 0.033 12.5 1.8 0.055 11.7 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Nol1_Nop2_Fmu PF01189.12 CCL98803.1 - 4.9e-18 65.4 0.0 1.1e-16 61.0 0.0 2.3 1 1 0 1 1 1 1 NOL1/NOP2/sun family zf-CCHC PF00098.18 CCL98804.1 - 1.5e-11 43.6 7.7 1.8e-05 24.4 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CCL98804.1 - 1.4e-06 27.8 3.6 0.0024 17.5 1.0 2.4 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 CCL98804.1 - 0.00018 21.0 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CCL98804.1 - 0.00049 19.6 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 CCL98804.1 - 0.0016 18.0 6.1 0.31 10.7 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 CCL98804.1 - 0.0084 15.7 8.9 0.52 10.0 0.2 3.0 3 0 0 3 3 3 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CCL98804.1 - 0.056 13.4 5.2 0.12 12.4 3.6 1.5 1 0 0 1 1 1 0 DnaJ central domain DUF605 PF04652.11 CCL98804.1 - 7 5.9 15.6 0.052 12.9 4.6 1.9 2 0 0 2 2 2 0 Vta1 like Helicase_C_3 PF13625.1 CCL98805.1 - 5.1e-28 97.4 0.1 2.8e-27 94.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCL98805.1 - 5.9e-15 55.5 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCL98805.1 - 2.8e-14 52.6 0.1 5.5e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCL98805.1 - 9.2e-10 38.2 0.0 2.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ROKNT PF08067.6 CCL98805.1 - 0.0069 16.2 0.3 0.028 14.2 0.2 2.1 1 0 0 1 1 1 1 ROKNT (NUC014) domain AAA_34 PF13872.1 CCL98805.1 - 0.027 13.2 0.1 0.048 12.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 bZIP_1 PF00170.16 CCL98806.1 - 0.053 13.4 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 CCL98806.1 - 0.091 12.5 0.5 0.14 11.9 0.4 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Mto2_bdg PF12808.2 CCL98806.1 - 0.15 12.2 0.1 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WD40_alt PF14077.1 CCL98806.1 - 0.15 11.7 0.1 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF1687 PF07955.6 CCL98807.1 - 4.6e-13 49.2 0.0 5.6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Peptidase_S3 PF00944.14 CCL98808.1 - 0.0037 16.6 0.0 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Alphavirus core protein Peptidase_S32 PF05579.8 CCL98808.1 - 0.019 13.9 0.1 0.042 12.8 0.1 1.5 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Glyco_hydro_14 PF01373.12 CCL98808.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 OPT PF03169.10 CCL98811.1 - 2.4e-144 482.1 53.3 2.2e-118 396.4 25.0 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein Diphtheria_C PF02763.9 CCL98812.1 - 0.061 12.7 0.2 0.41 10.0 0.0 1.9 1 1 1 2 2 2 0 Diphtheria toxin, C domain Abhydrolase_6 PF12697.2 CCL98815.1 - 5.8e-25 88.5 0.2 6.9e-25 88.2 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98815.1 - 1.1e-14 54.5 0.0 2e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL98815.1 - 2.6e-06 27.2 0.0 4.5e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCL98815.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase ATP1G1_PLM_MAT8 PF02038.11 CCL98816.1 - 1.5 7.9 3.1 3 6.9 0.1 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Pex14_N PF04695.8 CCL98817.1 - 0.024 14.6 1.3 0.039 14.0 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SLBP_RNA_bind PF15247.1 CCL98817.1 - 3 7.6 8.4 0.17 11.7 0.5 2.7 3 0 0 3 3 3 0 Histone RNA hairpin-binding protein RNA-binding domain SLBP_RNA_bind PF15247.1 CCL98818.1 - 0.02 14.6 4.4 0.023 14.4 0.8 2.1 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain F-box PF00646.28 CCL98819.1 - 0.00019 20.9 0.5 0.00059 19.4 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCL98819.1 - 0.0012 18.4 4.6 0.0029 17.3 3.2 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 CCL98820.1 - 7.4e-77 250.7 10.1 1.1e-11 44.1 0.1 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 CCL98820.1 - 2.4e-07 29.2 2.7 0.046 11.8 0.0 4.5 2 1 1 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 CCL98820.1 - 2.7e-06 26.8 0.0 1.2 8.9 0.0 5.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 CCL98820.1 - 4.4e-06 25.2 0.9 0.0014 17.0 0.1 3.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CCL98820.1 - 0.0041 15.9 0.1 3.2 6.3 0.0 3.1 1 1 1 3 3 3 1 Nup133 N terminal like Proteasome_A_N PF10584.4 CCL98820.1 - 0.0061 15.8 0.7 9.5 5.6 0.0 3.9 5 0 0 5 5 5 2 Proteasome subunit A N-terminal signature FIST PF08495.5 CCL98820.1 - 0.051 12.7 0.2 0.68 9.0 0.0 2.6 2 0 0 2 2 2 0 FIST N domain Kelch_6 PF13964.1 CCL98820.1 - 0.092 12.9 0.2 6.2 7.1 0.0 3.0 3 0 0 3 3 3 0 Kelch motif PQQ_3 PF13570.1 CCL98820.1 - 0.31 11.3 6.3 3.6 7.9 0.2 4.7 5 1 0 5 5 5 0 PQQ-like domain DUF2207 PF09972.4 CCL98821.1 - 1.5 7.2 3.6 4.2 5.8 2.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RRM_1 PF00076.17 CCL98822.1 - 1.7e-32 110.8 0.0 5.8e-11 41.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL98822.1 - 2.1e-27 94.8 0.0 4e-08 33.1 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL98822.1 - 1.1e-12 47.5 0.0 0.011 15.5 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phosphorylase PF00343.15 CCL98823.1 - 9e-297 985.8 0.0 1.1e-296 985.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF1708 PF08101.6 CCL98824.1 - 9e-16 57.7 0.1 3.1e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 CCL98824.1 - 0.024 14.2 0.0 0.055 13.0 0.0 1.6 1 1 0 1 1 1 0 RhoGAP domain UQ_con PF00179.21 CCL98825.1 - 1.7e-38 131.1 0.0 3e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SRP9-21 PF05486.7 CCL98826.1 - 1.8e-17 62.8 0.2 3.5e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Mito_carr PF00153.22 CCL98827.1 - 5.8e-53 176.5 2.3 1.5e-19 69.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.7 CCL98827.1 - 0.12 12.6 0.6 0.48 10.7 0.1 2.2 2 0 0 2 2 2 0 The GLUG motif DUF2207 PF09972.4 CCL98828.1 - 0.33 9.4 4.0 7 5.1 2.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 CCL98828.1 - 3.8 6.8 16.8 0.48 9.8 4.9 2.7 1 1 1 2 2 2 0 Fatty acid desaturase Cyt_c_ox_IV PF12270.3 CCL98828.1 - 4.9 6.8 10.4 84 2.9 4.5 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Amino_oxidase PF01593.19 CCL98831.1 - 1.2e-64 219.0 0.1 9.4e-49 166.6 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCL98831.1 - 2.8e-09 36.8 0.3 1.5e-08 34.5 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CCL98831.1 - 2.2e-05 23.7 0.1 3.1e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCL98831.1 - 6.3e-05 22.1 0.7 9.7e-05 21.5 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CCL98831.1 - 0.00011 22.2 1.6 0.00097 19.2 0.7 2.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCL98831.1 - 0.00091 18.1 1.3 0.0019 17.0 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 CCL98831.1 - 0.0048 17.0 0.0 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 CCL98831.1 - 0.0089 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCL98831.1 - 0.0099 14.8 1.5 0.0099 14.8 1.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCL98831.1 - 0.024 15.0 0.2 0.024 15.0 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CCL98831.1 - 0.036 13.6 0.1 0.076 12.5 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 CCL98831.1 - 0.041 12.7 0.3 0.065 12.0 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 CCL98831.1 - 0.12 10.7 0.8 0.2 10.1 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 CCL98831.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family adh_short PF00106.20 CCL98832.1 - 2.3e-20 73.1 2.9 2.3e-20 73.1 2.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCL98832.1 - 9.4e-11 41.7 2.3 9.3e-10 38.4 1.6 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCL98832.1 - 6.7e-10 39.1 2.3 8.7e-10 38.7 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCL98832.1 - 0.00014 21.9 2.5 0.003 17.5 0.7 2.5 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CCL98832.1 - 0.00053 19.4 1.8 0.0017 17.8 1.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCL98832.1 - 0.00066 19.9 0.3 0.33 11.2 0.0 2.5 2 0 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 CCL98832.1 - 0.0093 15.9 0.8 0.23 11.4 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain MT PF12777.2 CCL98832.1 - 0.042 12.5 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor GidB PF02527.10 CCL98832.1 - 0.12 11.5 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G adh_short PF00106.20 CCL98833.1 - 8.5e-20 71.3 0.2 1.5e-19 70.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCL98833.1 - 1.2e-09 38.3 0.3 1.5e-09 38.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCL98833.1 - 1.2e-08 34.8 0.0 4.1e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.13 CCL98833.1 - 0.002 18.1 0.4 0.037 14.0 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain Semialdhyde_dh PF01118.19 CCL98833.1 - 0.0072 16.6 0.3 2.9 8.2 0.0 2.6 2 1 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain ACP_syn_III PF08545.5 CCL98833.1 - 0.085 12.5 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4158 PF13700.1 CCL98833.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) adh_short PF00106.20 CCL98834.1 - 0.0062 16.4 0.0 4.6 7.1 0.0 3.4 3 1 1 4 4 4 2 short chain dehydrogenase adh_short PF00106.20 CCL98835.1 - 1.6e-18 67.1 3.5 2.1e-18 66.8 1.8 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCL98835.1 - 8.6e-15 55.1 0.4 1.1e-14 54.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCL98835.1 - 1.4e-07 31.3 2.7 4.6e-07 29.6 1.9 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CCL98835.1 - 0.00014 21.4 0.1 0.0002 20.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCL98835.1 - 0.00062 19.8 0.5 0.0032 17.5 0.3 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCL98835.1 - 0.0087 14.7 0.1 0.013 14.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 CCL98835.1 - 0.027 14.4 0.2 0.06 13.3 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain ABC_tran PF00005.22 CCL98836.1 - 7.1e-51 172.0 0.0 1.1e-25 90.4 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CCL98836.1 - 5.9e-22 78.9 0.1 3.3e-06 27.2 0.0 4.3 4 0 0 4 4 4 4 AAA domain ABC2_membrane_3 PF12698.2 CCL98836.1 - 5.9e-21 74.8 44.3 3.5e-14 52.6 17.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_23 PF13476.1 CCL98836.1 - 7.4e-08 32.9 1.2 0.0042 17.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCL98836.1 - 7.4e-06 25.4 1.7 0.067 12.7 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CCL98836.1 - 1.9e-05 23.9 3.0 0.82 8.8 0.1 4.2 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CCL98836.1 - 0.001 18.2 0.3 1.5 8.0 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function, DUF258 SRP54 PF00448.17 CCL98836.1 - 0.0024 17.3 1.5 0.84 9.0 0.3 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_15 PF13175.1 CCL98836.1 - 0.0076 15.3 0.0 0.61 9.0 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 CCL98836.1 - 0.012 15.1 2.4 4.2 6.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CCL98836.1 - 0.021 13.9 0.1 4.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 CCL98836.1 - 0.027 14.6 2.1 6 7.0 0.0 3.4 2 2 0 2 2 2 0 AAA domain DUF4162 PF13732.1 CCL98836.1 - 0.038 14.4 0.0 8.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) MutS_V PF00488.16 CCL98836.1 - 0.077 12.3 0.7 4.4 6.6 0.1 2.9 3 0 0 3 3 3 0 MutS domain V MukB PF04310.7 CCL98836.1 - 0.092 12.0 0.4 7.7 5.7 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_16 PF13191.1 CCL98836.1 - 0.26 11.2 2.0 17 5.3 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.24 CCL98836.1 - 0.36 11.0 1.2 19 5.4 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CCL98836.1 - 0.37 10.1 1.5 17 4.7 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 CCL98836.1 - 0.82 9.6 3.7 18 5.2 0.2 2.7 3 0 0 3 3 2 0 AAA domain Dynactin PF12455.3 CCL98838.1 - 4.5e-84 281.6 1.9 4.5e-84 281.6 1.3 2.9 3 2 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 CCL98838.1 - 1.2e-23 82.5 1.4 2e-23 81.8 0.7 1.7 2 0 0 2 2 2 1 CAP-Gly domain DUF869 PF05911.6 CCL98838.1 - 0.0017 16.6 4.6 0.0017 16.6 3.2 3.0 2 1 1 3 3 3 1 Plant protein of unknown function (DUF869) HATPase_c PF02518.21 CCL98839.1 - 4.4e-27 93.9 0.4 3.4e-26 91.1 0.0 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MHYT PF03707.11 CCL98839.1 - 1.7e-22 79.2 28.4 6.7e-12 45.3 2.7 3.8 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat Response_reg PF00072.19 CCL98839.1 - 3.8e-21 75.1 0.0 1.6e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 CCL98839.1 - 1e-14 54.2 0.0 2.9e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 CCL98839.1 - 0.00014 21.5 0.0 0.00044 19.9 0.0 1.9 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 CCL98839.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Metalloenzyme PF01676.13 CCL98840.1 - 3.5e-77 259.1 0.9 4.2e-77 258.9 0.6 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 CCL98840.1 - 1.1e-74 250.5 0.0 1.6e-74 250.0 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Sulfatase PF00884.18 CCL98840.1 - 1.1e-05 24.8 0.1 0.00014 21.2 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CCL98840.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.7 CCL98840.1 - 0.06 13.0 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 PglZ domain Tetraspannin PF00335.15 CCL98841.1 - 6.5e-09 35.3 13.9 1.1e-08 34.6 9.6 1.4 1 1 0 1 1 1 1 Tetraspanin family SSrecog PF03531.9 CCL98842.1 - 6.1e-76 254.6 0.0 1e-75 253.8 0.0 1.4 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CCL98842.1 - 2.4e-23 81.8 0.1 2.4e-21 75.5 0.0 2.4 2 0 0 2 2 2 2 Histone chaperone Rttp106-like DUF2201_N PF13203.1 CCL98842.1 - 0.49 9.5 0.0 0.49 9.5 0.0 2.5 2 1 0 2 2 2 0 Putative metallopeptidase domain CH PF00307.26 CCL98843.1 - 8.2e-37 125.5 0.0 6.4e-24 84.0 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 CCL98843.1 - 7.9e-18 64.2 0.0 2.9e-17 62.4 0.0 2.1 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 CCL98843.1 - 2.3e-12 46.3 0.3 2.6e-10 39.8 0.1 2.6 2 0 0 2 2 2 1 CAMSAP CH domain Spectrin PF00435.16 CCL98843.1 - 6.4e-05 23.1 2.3 0.05 13.8 0.1 2.9 3 0 0 3 3 2 2 Spectrin repeat EF-hand_6 PF13405.1 CCL98843.1 - 0.00041 19.9 0.1 0.0053 16.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain Med9 PF07544.8 CCL98843.1 - 0.00088 18.9 3.1 0.12 12.0 0.1 3.7 3 1 1 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 EF-hand_7 PF13499.1 CCL98843.1 - 0.014 15.5 0.6 0.12 12.5 0.4 2.4 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 CCL98843.1 - 0.02 14.1 0.0 0.077 12.3 0.0 2.1 1 0 0 1 1 1 0 EF hand Baculo_PEP_C PF04513.7 CCL98843.1 - 0.025 14.4 2.9 0.057 13.2 0.1 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 CCL98843.1 - 0.027 13.1 2.5 0.059 12.0 1.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.6 CCL98843.1 - 0.039 13.8 1.2 0.077 12.8 0.0 2.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RyR PF02026.11 CCL98843.1 - 0.043 13.8 0.8 2.6 8.1 0.3 2.6 2 0 0 2 2 2 0 RyR domain Syntaxin PF00804.20 CCL98843.1 - 0.067 13.3 6.0 6 7.0 1.0 3.9 1 1 1 2 2 2 0 Syntaxin SF-assemblin PF06705.6 CCL98843.1 - 0.21 10.7 7.3 0.031 13.4 2.3 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin CENP-F_leu_zip PF10473.4 CCL98843.1 - 0.28 11.0 2.7 0.69 9.7 1.9 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.7 CCL98843.1 - 3.3 6.0 5.5 3.9 5.7 0.4 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Fib_alpha PF08702.5 CCL98843.1 - 6.6 6.8 6.6 4 7.5 0.1 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Cofilin_ADF PF00241.15 CCL98844.1 - 3.6e-40 136.7 0.5 4.2e-40 136.5 0.3 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MmgE_PrpD PF03972.9 CCL98845.1 - 5.6e-119 397.2 0.0 6.7e-119 396.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DLH PF01738.13 CCL98846.1 - 6.8e-24 84.3 0.0 1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCL98846.1 - 1.9e-06 27.6 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCL98846.1 - 0.00013 21.9 0.1 0.00099 19.0 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 CCL98846.1 - 0.036 13.7 0.0 0.12 12.0 0.0 1.7 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Amino_oxidase PF01593.19 CCL98847.1 - 6.6e-33 114.4 0.0 8.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCL98847.1 - 2.9e-07 30.4 0.0 7.4e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCL98847.1 - 0.018 13.5 0.1 0.052 12.0 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 CCL98847.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCL98847.1 - 0.11 11.5 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Porin_3 PF01459.17 CCL98848.1 - 3.8e-67 226.4 0.7 4.2e-67 226.3 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rhodanese PF00581.15 CCL98849.1 - 5.4e-08 33.1 0.0 6.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF3767 PF12597.3 CCL98850.1 - 3.8e-31 107.1 0.0 4.6e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) MIP PF00230.15 CCL98851.1 - 7.2e-49 166.2 6.0 2.5e-48 164.5 4.2 1.7 1 1 0 1 1 1 1 Major intrinsic protein DUF500 PF04366.7 CCL98852.1 - 5.7e-45 151.8 0.1 1.1e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Phosphodiest PF01663.17 CCL98853.1 - 4.1e-69 233.6 0.4 6e-69 233.1 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Dynactin_p62 PF05502.8 CCL98854.1 - 6e-49 167.1 0.0 1.7e-33 116.1 0.0 2.0 1 1 1 2 2 2 2 Dynactin p62 family Trs65 PF12735.2 CCL98855.1 - 0.064 12.5 1.0 0.1 11.9 0.7 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 MGC-24 PF05283.6 CCL98855.1 - 0.64 9.7 4.3 1.4 8.7 3.0 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Gemini_mov PF01708.11 CCL98855.1 - 1.2 8.6 3.0 0.64 9.6 0.1 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein Glyco_hydro_15 PF00723.16 CCL98856.1 - 5.3e-96 321.9 0.1 6.2e-96 321.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 CCL98856.1 - 1.8e-26 91.5 1.0 1.8e-26 91.5 0.7 1.9 2 0 0 2 2 2 1 Starch binding domain NTR2 PF15458.1 CCL98857.1 - 1.4e-60 204.7 7.0 1.4e-60 204.7 4.8 2.4 3 1 0 3 3 3 1 Nineteen complex-related protein 2 GCFC PF07842.7 CCL98857.1 - 0.0027 17.0 0.0 0.01 15.2 0.0 1.9 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Rad60-SLD PF11976.3 CCL98858.1 - 1.5e-09 37.4 0.0 0.00022 20.8 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like LRR_6 PF13516.1 CCL98859.1 - 7.6e-17 59.4 0.7 0.22 11.6 0.0 7.5 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.2 CCL98859.1 - 8.3e-11 41.2 0.3 0.0016 18.0 1.2 5.6 4 1 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCL98859.1 - 5.2e-07 28.8 0.0 8.3 6.8 0.1 6.7 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 CCL98859.1 - 0.00083 19.0 6.9 0.85 9.4 0.0 4.3 4 3 0 4 4 4 2 Leucine rich repeat Nucleoplasmin PF03066.10 CCL98859.1 - 0.0048 16.4 4.3 0.0074 15.8 3.0 1.3 1 0 0 1 1 1 1 Nucleoplasmin LRR_7 PF13504.1 CCL98859.1 - 0.029 14.5 6.7 11 6.7 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat VID27 PF08553.5 CCL98859.1 - 0.82 7.8 6.0 1.1 7.3 4.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein BSP_II PF05432.6 CCL98859.1 - 2.8 7.1 13.0 4.4 6.5 9.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Phosphodiest PF01663.17 CCL98860.1 - 1e-10 41.5 0.5 2.1e-10 40.4 0.3 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Terpene_synth_C PF03936.11 CCL98860.1 - 5.4e-06 25.8 0.1 0.0012 18.0 0.0 2.3 1 1 1 2 2 2 2 Terpene synthase family, metal binding domain Metalloenzyme PF01676.13 CCL98860.1 - 0.00032 20.1 0.1 0.00054 19.4 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CCL98860.1 - 0.0014 17.8 0.0 0.056 12.6 0.0 2.3 2 0 0 2 2 2 1 Sulfatase Fungal_trans PF04082.13 CCL98861.1 - 2.4e-09 36.4 0.1 5e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain CBFD_NFYB_HMF PF00808.18 CCL98862.1 - 0.00017 21.5 0.0 0.079 13.0 0.1 2.5 1 1 1 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAM91_C PF14648.1 CCL98862.1 - 0.036 12.8 0.8 0.053 12.3 0.6 1.1 1 0 0 1 1 1 0 FAM91 C-terminus BUD22 PF09073.5 CCL98862.1 - 0.82 8.6 19.1 1.1 8.2 13.2 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CCL98862.1 - 9.5 3.9 18.8 12 3.6 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family F-box-like PF12937.2 CCL98863.1 - 7.4e-08 32.0 0.4 2.2e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like Rhodanese PF00581.15 CCL98864.1 - 9.1e-06 26.0 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_hydro_42M PF08532.5 CCL98864.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain ABC_tran PF00005.22 CCL98867.1 - 4.9e-45 153.1 0.1 6.3e-27 94.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCL98867.1 - 3e-39 135.0 30.3 4.9e-21 75.3 5.8 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 CCL98867.1 - 6.2e-11 41.9 4.2 0.011 14.9 0.2 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCL98867.1 - 1.1e-09 38.6 6.0 0.012 15.5 0.2 4.7 3 2 1 4 4 3 3 AAA domain AAA_25 PF13481.1 CCL98867.1 - 2.5e-08 33.5 0.8 0.0076 15.6 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 CCL98867.1 - 1.1e-07 32.4 0.5 0.00024 21.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CCL98867.1 - 7.6e-07 28.5 0.0 0.041 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CCL98867.1 - 8.8e-06 25.8 1.1 0.099 12.6 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 CCL98867.1 - 2.3e-05 23.4 0.0 0.017 14.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CCL98867.1 - 4.3e-05 23.0 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CCL98867.1 - 6.7e-05 22.8 0.0 0.12 12.3 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 CCL98867.1 - 0.0001 22.0 0.4 0.38 10.4 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CCL98867.1 - 0.00014 22.6 0.0 1.1 10.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CCL98867.1 - 0.00025 20.8 0.1 0.014 15.0 0.0 2.8 2 1 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 CCL98867.1 - 0.00037 19.7 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 CCL98867.1 - 0.0004 20.8 0.0 0.89 10.0 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CCL98867.1 - 0.00056 20.0 1.5 0.35 11.0 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCL98867.1 - 0.00065 20.0 0.2 1.6 9.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 CCL98867.1 - 0.00067 19.5 0.3 0.048 13.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 IstB_IS21 PF01695.12 CCL98867.1 - 0.00081 18.8 0.3 2.8 7.3 0.0 3.7 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_5 PF07728.9 CCL98867.1 - 0.0031 17.2 0.3 7.4 6.2 0.0 4.2 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CCL98867.1 - 0.005 16.3 2.5 1.8 7.9 0.0 3.0 2 1 0 3 3 3 1 AAA-like domain Pox_A32 PF04665.7 CCL98867.1 - 0.0066 15.7 0.1 3 7.0 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Zeta_toxin PF06414.7 CCL98867.1 - 0.0073 15.4 0.0 0.41 9.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 CCL98867.1 - 0.0081 15.8 0.0 0.7 9.6 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain Adeno_IVa2 PF02456.10 CCL98867.1 - 0.0091 14.6 0.0 0.051 12.2 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein Dynamin_N PF00350.18 CCL98867.1 - 0.021 14.6 0.6 1.5 8.6 0.0 2.7 2 0 0 2 2 2 0 Dynamin family DEAD PF00270.24 CCL98867.1 - 0.022 14.2 0.1 8.3 5.8 0.1 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.10 CCL98867.1 - 0.039 13.7 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 CCL98867.1 - 0.053 13.3 0.1 0.94 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CCL98867.1 - 0.067 12.8 0.8 1.8 8.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 CCL98867.1 - 0.085 12.2 1.6 0.59 9.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 CCL98867.1 - 0.12 11.9 0.1 0.64 9.5 0.0 2.2 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 CCL98867.1 - 0.12 11.8 0.6 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 CCL98867.1 - 0.21 10.5 0.0 0.43 9.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 CCL98867.1 - 0.43 10.7 1.3 33 4.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase DUF455 PF04305.9 CCL98868.1 - 1.9e-82 276.3 0.1 3.7e-82 275.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF455) RicinB_lectin_2 PF14200.1 CCL98868.1 - 3.2e-12 46.7 0.0 5.2e-08 33.1 0.0 2.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Rieske PF00355.21 CCL98868.1 - 0.0029 17.1 0.0 0.007 15.9 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ricin_B_lectin PF00652.17 CCL98868.1 - 0.036 14.0 0.0 0.15 12.0 0.0 2.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain HTH_29 PF13551.1 CCL98869.1 - 0.041 14.0 0.2 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Fungal_trans PF04082.13 CCL98870.1 - 9.6e-15 54.1 0.4 1.7e-14 53.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 7tm_1 PF00001.16 CCL98871.1 - 0.088 11.9 0.4 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.20 CCL98872.1 - 1.3e-71 240.8 0.0 3e-71 239.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98872.1 - 3.3e-36 124.6 0.0 9.4e-36 123.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CCL98872.1 - 9.6e-09 34.5 0.0 1.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 CCL98872.1 - 4.2e-06 25.9 0.1 7.3e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCL98872.1 - 4.2e-05 22.6 0.0 0.00012 21.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCL98872.1 - 0.00012 21.8 0.0 0.0023 17.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 CCL98872.1 - 0.0064 15.7 0.4 0.01 15.0 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 CCL98872.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Rad60-SLD PF11976.3 CCL98873.1 - 4.8e-14 51.7 0.0 5.8e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CCL98873.1 - 2e-06 27.1 0.0 2.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.3 CCL98873.1 - 0.0007 19.4 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 GLUT4 regulating protein TUG ATG22 PF11700.3 CCL98874.1 - 1.5e-121 406.2 13.3 1.8e-121 405.9 9.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CCL98874.1 - 3.2e-10 39.2 48.1 2.4e-06 26.5 18.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Mito_carr PF00153.22 CCL98875.1 - 1.1e-22 79.5 5.7 1.9e-08 33.8 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIS_M PF07500.9 CCL98876.1 - 1.3e-32 112.2 2.8 3.8e-32 110.7 0.0 2.3 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 CCL98876.1 - 3.2e-13 48.9 1.9 7.1e-13 47.8 1.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.13 CCL98876.1 - 1.3e-11 43.9 4.9 2.1e-11 43.2 3.4 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Erp_C PF06780.6 CCL98876.1 - 0.01 15.6 1.2 0.021 14.6 0.0 1.9 2 1 0 2 2 2 0 Erp protein C-terminus Pol_alpha_B_N PF08418.5 CCL98876.1 - 0.11 11.9 2.3 0.16 11.4 1.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3713 PF12506.3 CCL98876.1 - 2.2 8.3 4.5 2.1 8.4 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) WD40 PF00400.27 CCL98878.1 - 4.1e-52 172.2 18.5 7.2e-09 35.1 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 CCL98878.1 - 0.033 13.6 1.0 1.5 8.2 0.1 2.7 1 1 2 3 3 3 0 PQQ-like domain Nup160 PF11715.3 CCL98878.1 - 0.11 10.6 2.8 12 3.8 0.1 3.6 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Peptidase_M48 PF01435.13 CCL98879.1 - 3e-45 154.5 0.1 4.3e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 CCL98879.1 - 0.091 11.7 0.2 0.15 11.0 0.2 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Piwi PF02171.12 CCL98880.1 - 4.5e-72 242.5 0.0 8.6e-72 241.6 0.0 1.5 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CCL98880.1 - 6.6e-14 51.3 0.0 1.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CCL98880.1 - 4.2e-09 35.6 0.0 1.2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) p450 PF00067.17 CCL98881.1 - 1.5e-51 175.3 0.0 2.1e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3206 PF11472.3 CCL98881.1 - 0.065 13.0 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) Piwi PF02171.12 CCL98882.1 - 4.2e-71 239.3 0.0 5.9e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CCL98882.1 - 1e-18 66.9 0.0 2.7e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CCL98882.1 - 1.9e-12 46.3 0.3 5.6e-12 44.8 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Pyr_redox_3 PF13738.1 CCL98883.1 - 6.3e-18 65.5 0.7 2.5e-15 57.1 0.9 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCL98883.1 - 7.7e-12 44.1 0.0 4.5e-05 21.8 0.0 3.1 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CCL98883.1 - 4.2e-11 43.1 0.7 0.00027 20.8 0.1 2.8 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCL98883.1 - 6.5e-09 35.6 4.6 6.8e-09 35.6 0.1 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCL98883.1 - 1.5e-08 33.9 0.3 1.5e-08 33.9 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCL98883.1 - 3.2e-07 30.6 2.6 0.0035 17.7 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCL98883.1 - 3.5e-06 26.3 3.3 4.1e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CCL98883.1 - 8e-06 24.9 2.6 0.00058 18.8 0.2 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.1 CCL98883.1 - 1e-05 24.6 0.2 0.01 14.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 CCL98883.1 - 1.3e-05 23.8 1.1 0.0024 16.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 CCL98883.1 - 3.6e-05 22.7 0.4 3.6e-05 22.7 0.3 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 CCL98883.1 - 0.00041 20.5 0.0 0.086 13.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCL98883.1 - 0.00053 20.0 0.1 0.048 13.7 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CCL98883.1 - 0.00062 19.4 0.3 0.00062 19.4 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 CCL98883.1 - 0.0011 18.6 2.5 0.14 11.9 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 CCL98883.1 - 0.0035 16.4 0.1 0.012 14.6 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 CCL98883.1 - 0.012 15.1 5.1 1.6 8.3 0.3 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain PA PF02225.17 CCL98883.1 - 0.031 13.9 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 PA domain FAD_binding_3 PF01494.14 CCL98883.1 - 0.078 12.0 4.0 0.32 10.0 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 CCL98883.1 - 0.1 11.9 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 CCL98883.1 - 0.12 12.3 3.3 4.2 7.3 0.2 2.5 2 0 0 2 2 2 0 NADH(P)-binding Thi4 PF01946.12 CCL98883.1 - 0.84 8.6 2.7 1.2 8.1 0.2 2.1 2 0 0 2 2 2 0 Thi4 family zf-Di19 PF05605.7 CCL98885.1 - 0.042 13.9 1.8 0.042 13.9 1.2 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CCL98885.1 - 0.084 13.2 1.4 0.5 10.8 1.0 2.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCL98885.1 - 2.2 8.8 8.3 0.22 11.9 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger TPR_11 PF13414.1 CCL98887.1 - 8.5e-51 169.4 7.3 7.2e-15 54.3 0.0 6.6 4 2 2 6 6 6 5 TPR repeat TPR_2 PF07719.12 CCL98887.1 - 5.9e-37 122.6 9.9 2.9e-05 23.6 0.0 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 CCL98887.1 - 5e-36 120.8 12.1 8.9e-06 25.0 0.0 10.4 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 CCL98887.1 - 1.9e-23 82.5 8.6 7e-07 29.7 0.0 5.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCL98887.1 - 3.1e-21 73.7 1.6 0.004 17.2 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCL98887.1 - 2.4e-18 64.9 7.8 3e-05 24.2 0.0 7.8 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCL98887.1 - 4.3e-17 61.8 13.4 7.9e-06 25.7 0.0 7.1 3 1 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCL98887.1 - 7.5e-14 51.8 9.3 0.00017 21.8 0.0 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 CCL98887.1 - 9.8e-13 48.0 5.0 0.0016 18.5 0.0 4.5 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCL98887.1 - 2e-12 45.9 5.8 0.03 14.0 0.0 7.9 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCL98887.1 - 2.2e-12 45.8 8.4 0.00021 20.8 0.0 7.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCL98887.1 - 6.8e-10 38.6 6.7 0.0029 17.3 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCL98887.1 - 5.5e-05 22.3 3.0 0.02 13.9 0.0 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCL98887.1 - 6e-05 23.2 14.4 1.2 9.7 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat NARP1 PF12569.3 CCL98887.1 - 0.0031 16.3 0.0 0.0031 16.3 0.0 3.2 4 0 0 4 4 4 1 NMDA receptor-regulated protein 1 DUF3856 PF12968.2 CCL98887.1 - 0.0038 17.0 0.9 1.3 8.8 0.2 3.7 2 2 0 2 2 2 1 Domain of Unknown Function (DUF3856) PPR PF01535.15 CCL98887.1 - 0.0099 15.8 0.0 0.66 10.0 0.0 3.0 2 0 0 2 2 2 1 PPR repeat Phage_term_smal PF05944.7 CCL98887.1 - 0.031 13.9 1.7 0.13 11.9 0.0 2.7 3 0 0 3 3 2 0 Phage small terminase subunit TPR_20 PF14561.1 CCL98887.1 - 0.046 13.8 11.9 15 5.8 0.0 5.9 5 2 1 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCL98887.1 - 0.063 13.1 0.3 4.7 7.1 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 CCL98887.1 - 0.7 10.1 6.0 8.8 6.6 0.4 4.0 3 1 0 4 4 4 0 Bacterial transcriptional activator domain Diphthamide_syn PF01866.12 CCL98888.1 - 1.6e-38 132.7 0.0 1.3e-19 70.6 0.0 2.6 1 1 1 2 2 2 2 Putative diphthamide synthesis protein AA_permease PF00324.16 CCL98889.1 - 0.1 10.8 0.2 0.15 10.3 0.1 1.1 1 0 0 1 1 1 0 Amino acid permease SseC PF04888.7 CCL98890.1 - 0.031 13.6 0.6 0.034 13.4 0.4 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ABC_sub_bind PF04392.7 CCL98890.1 - 0.042 12.8 0.2 0.049 12.5 0.1 1.0 1 0 0 1 1 1 0 ABC transporter substrate binding protein Holin_LLH PF09682.5 CCL98890.1 - 0.079 13.0 0.8 0.097 12.7 0.5 1.2 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) SSP160 PF06933.6 CCL98891.1 - 2.1 6.2 11.5 3.2 5.6 8.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 CCL98891.1 - 2.2 8.0 17.3 0.11 12.2 8.1 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Rubella_E2 PF05749.6 CCL98891.1 - 3.2 6.9 13.9 5.9 6.0 9.6 1.5 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 DUF3439 PF11921.3 CCL98891.1 - 3.5 7.3 11.7 0.21 11.3 4.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.19 CCL98892.1 - 4.2e-126 421.1 15.5 4.8e-126 420.9 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCL98892.1 - 2.5e-21 75.8 36.2 1.5e-15 56.8 9.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily V1R PF03402.9 CCL98895.1 - 0.1 11.9 0.4 1.7 7.9 0.3 2.1 2 0 0 2 2 2 0 Vomeronasal organ pheromone receptor family, V1R DUF202 PF02656.10 CCL98896.1 - 0.011 15.8 1.8 0.023 14.9 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) TMEM154 PF15102.1 CCL98897.1 - 0.00043 19.9 0.1 0.00084 19.0 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family FixQ PF05545.6 CCL98897.1 - 0.0011 18.6 0.4 0.002 17.7 0.3 1.4 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ BatD PF13584.1 CCL98897.1 - 0.037 12.6 0.1 0.048 12.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance RDD PF06271.7 CCL98897.1 - 0.06 13.2 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 RDD family SOBP PF15279.1 CCL98897.1 - 0.072 13.4 3.0 0.096 13.0 2.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 CCL98897.1 - 0.32 9.2 4.8 0.34 9.1 3.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Epimerase PF01370.16 CCL98898.1 - 3.4e-40 137.9 0.0 4.5e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CCL98898.1 - 1.7e-25 88.7 0.2 3.1e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit RmlD_sub_bind PF04321.12 CCL98898.1 - 1.2e-11 44.0 0.0 4.8e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CCL98898.1 - 3.3e-11 42.3 0.0 1.3e-10 40.4 0.0 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CCL98898.1 - 1.4e-09 37.2 0.0 9.5e-09 34.5 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 CCL98898.1 - 1.8e-09 36.9 0.0 2.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCL98898.1 - 2.9e-08 33.8 0.0 4.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCL98898.1 - 1.8e-07 31.0 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCL98898.1 - 0.00021 21.3 0.0 0.01 15.8 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 CCL98898.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus YcfA PF07927.7 CCL98898.1 - 0.025 14.4 0.1 0.097 12.6 0.0 1.9 2 0 0 2 2 2 0 YcfA-like protein efThoc1 PF11957.3 CCL98899.1 - 7e-90 301.8 0.1 5.3e-84 282.4 0.0 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Tuberin PF03542.11 CCL98899.1 - 0.074 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Tuberin Rotamase PF00639.16 CCL98900.1 - 3e-23 82.3 0.0 4.1e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CCL98900.1 - 3.8e-20 72.2 0.0 5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CCL98900.1 - 5.1e-06 26.2 0.3 1.2e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 CCL98900.1 - 0.00014 22.4 0.0 0.00021 21.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Fungal_trans PF04082.13 CCL98901.1 - 6.8e-19 67.7 0.6 1.1e-18 67.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2235 PF09994.4 CCL98902.1 - 6.1e-75 252.1 0.0 7.8e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3850 PF12961.2 CCL98902.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) Abhydrolase_5 PF12695.2 CCL98902.1 - 0.055 13.2 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.17 CCL98903.1 - 1.5e-45 155.5 0.0 1.8e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CNF1 PF05785.7 CCL98903.1 - 0.19 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor p450 PF00067.17 CCL98904.1 - 1.2e-44 152.6 0.0 1.4e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF726 PF05277.7 CCL98905.1 - 2.2e-114 381.9 0.6 3.3e-114 381.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SRP14 PF02290.10 CCL98905.1 - 2.9e-19 68.7 0.0 7.3e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Abhydrolase_5 PF12695.2 CCL98905.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL98905.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TP_methylase PF00590.15 CCL98906.1 - 2.5e-36 125.3 0.9 4.1e-36 124.6 0.2 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 CCL98906.1 - 1.6e-11 44.3 0.1 4.4e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CCL98906.1 - 6.6e-07 28.5 0.2 1.6e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CCL98906.1 - 0.0051 15.7 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SMC_N PF02463.14 CCL98907.1 - 1.1e-76 256.9 0.0 2.1e-76 256.0 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCL98907.1 - 1.6e-25 89.3 0.0 6.4e-25 87.4 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCL98907.1 - 4.9e-11 43.1 17.1 3.3e-06 27.2 0.3 3.8 2 2 2 4 4 4 2 AAA domain AAA_23 PF13476.1 CCL98907.1 - 1.4e-09 38.6 20.5 1.4e-09 38.6 14.2 6.7 2 2 1 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 CCL98907.1 - 3.6e-09 36.2 22.2 0.00049 19.3 1.9 3.8 3 1 1 4 4 4 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 CCL98907.1 - 1e-06 28.1 0.0 2.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Fib_alpha PF08702.5 CCL98907.1 - 0.00049 20.2 2.2 0.00049 20.2 1.5 6.1 4 1 4 8 8 8 1 Fibrinogen alpha/beta chain family Shadoo PF14999.1 CCL98907.1 - 0.01 15.6 0.6 0.047 13.5 0.4 2.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective ABC_tran PF00005.22 CCL98907.1 - 0.24 11.6 0.0 0.24 11.6 0.0 5.5 3 2 0 3 3 3 0 ABC transporter Pkinase PF00069.20 CCL98908.1 - 1.4e-37 129.3 0.0 4.2e-37 127.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL98908.1 - 1.9e-17 63.2 0.0 2.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCL98908.1 - 0.0024 16.9 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FBPase PF00316.15 CCL98909.1 - 1.8e-129 431.2 0.0 2e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CCL98909.1 - 0.00019 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Nramp PF01566.13 CCL98911.1 - 3.2e-91 305.7 18.3 3.2e-49 167.6 1.3 2.8 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein Utp14 PF04615.8 CCL98912.1 - 6.5e-167 556.9 56.2 6.5e-167 556.9 38.9 2.7 1 1 1 2 2 2 1 Utp14 protein ubiquitin PF00240.18 CCL98913.1 - 5.7e-35 118.5 0.7 7.4e-35 118.1 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CCL98913.1 - 3.3e-28 97.0 4.3 5.3e-28 96.3 3.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CCL98913.1 - 5.4e-20 70.8 0.7 7.9e-20 70.3 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCL98913.1 - 7.4e-06 26.1 0.1 2.7e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCL98913.1 - 0.00017 21.3 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCL98913.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCL98913.1 - 0.016 15.3 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCL98913.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 CCL98913.1 - 0.4 10.5 1.9 0.54 10.0 0.1 1.9 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 CCL98913.1 - 0.43 9.9 2.2 0.61 9.4 1.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Adap_comp_sub PF00928.16 CCL98914.1 - 8.3e-19 67.7 0.0 1.3e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MBOAT_2 PF13813.1 CCL98914.1 - 1.3e-09 37.9 7.2 2e-09 37.4 4.1 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Clat_adaptor_s PF01217.15 CCL98914.1 - 2.7e-05 23.9 0.0 4.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain p450 PF00067.17 CCL98915.1 - 6e-48 163.5 0.0 7.6e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UPF0564 PF10595.4 CCL98916.1 - 0.00036 19.5 0.1 0.00065 18.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 TPX2 PF06886.6 CCL98916.1 - 0.0017 18.3 17.5 0.0017 18.3 12.1 2.0 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) Endonuc_Holl PF10107.4 CCL98916.1 - 1.7 8.3 2.0 2.8 7.6 1.4 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase 2-oxoacid_dh PF00198.18 CCL98917.1 - 6.4e-47 159.7 0.0 9.4e-46 155.9 0.0 2.1 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCL98917.1 - 2.4e-18 65.5 0.3 4.9e-18 64.5 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CCL98917.1 - 2.7e-10 39.6 1.0 5.2e-10 38.7 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CCL98917.1 - 0.001 18.6 0.1 0.0027 17.3 0.1 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like DHC_N1 PF08385.7 CCL98918.1 - 1.5e-197 657.5 9.4 6.8e-196 652.1 0.9 2.8 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 TORC_C PF12886.2 CCL98918.1 - 0.12 12.5 0.2 0.83 9.8 0.0 2.4 2 0 0 2 2 2 0 Transducer of regulated CREB activity, C terminus CBS PF00571.23 CCL98919.1 - 2e-06 27.4 0.3 0.13 12.0 0.0 3.0 3 0 0 3 3 3 2 CBS domain DUF21 PF01595.15 CCL98919.1 - 6.6e-06 25.5 0.0 0.021 14.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF21 tRNA_U5-meth_tr PF05958.6 CCL98920.1 - 9.5e-16 57.4 0.0 2.5e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CCL98920.1 - 5.4e-07 29.3 0.0 9.9e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CCL98920.1 - 3.2e-06 26.8 0.0 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CCL98920.1 - 9.6e-06 25.6 0.0 4.2e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCL98920.1 - 1.6e-05 25.4 0.0 3.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCL98920.1 - 0.0029 18.0 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCL98920.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 CCL98920.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PS_Dcarbxylase PF02666.10 CCL98921.1 - 8.6e-78 260.2 0.0 2.8e-59 199.8 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase Rtf2 PF04641.7 CCL98922.1 - 4.5e-71 239.0 0.5 5.5e-71 238.8 0.4 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 CCL98922.1 - 0.0029 17.0 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CCL98922.1 - 0.031 14.0 0.1 0.25 11.0 0.0 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Med21 PF11221.3 CCL98923.1 - 5.8e-21 74.9 7.5 3.5e-14 52.9 1.0 2.1 1 1 1 2 2 2 2 Subunit 21 of Mediator complex FlgN PF05130.7 CCL98923.1 - 0.081 13.1 3.0 0.15 12.2 2.0 1.5 1 1 0 1 1 1 0 FlgN protein Synaptobrevin PF00957.16 CCL98923.1 - 0.092 12.3 0.4 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Synaptobrevin Cep57_MT_bd PF06657.8 CCL98923.1 - 0.14 12.1 6.8 0.69 9.9 0.5 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4315 PF14193.1 CCL98923.1 - 0.2 11.6 1.0 0.96 9.4 0.2 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) Rabaptin PF03528.10 CCL98923.1 - 0.21 11.5 2.1 0.6 10.0 1.5 1.9 1 1 0 1 1 1 0 Rabaptin DELLA PF12041.3 CCL98923.1 - 0.42 10.2 2.3 0.5 10.0 0.2 2.0 2 1 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Cullin PF00888.17 CCL98924.1 - 7.2e-97 325.3 4.8 7.2e-97 325.3 3.3 1.6 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CCL98924.1 - 2.2e-24 85.0 0.8 6.8e-24 83.4 0.6 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3208 PF11482.3 CCL98924.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) DUF35_N PF12172.3 CCL98925.1 - 0.25 11.2 5.7 0.71 9.8 4.0 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) G-alpha PF00503.15 CCL98926.1 - 5.9e-108 361.0 0.2 7.1e-108 360.7 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCL98926.1 - 4.6e-13 48.7 3.0 5.8e-08 32.1 0.7 2.8 2 2 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CCL98926.1 - 0.00032 21.1 0.0 0.4 11.1 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 CCL98926.1 - 0.0043 16.4 0.2 3 7.2 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCL98926.1 - 0.015 15.2 0.0 8 6.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CCL98926.1 - 0.019 14.0 0.2 5.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 CCL98926.1 - 0.06 12.8 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CCL98926.1 - 0.14 11.5 0.0 3.1 7.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Gtr1_RagA PF04670.7 CCL98926.1 - 0.2 10.7 6.5 1.8 7.6 0.8 2.6 2 2 0 2 2 2 0 Gtr1/RagA G protein conserved region adh_short PF00106.20 CCL98927.1 - 2.2e-32 112.2 0.6 2.9e-32 111.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCL98927.1 - 4.7e-27 95.3 1.1 8.1e-27 94.5 0.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCL98927.1 - 2.8e-17 62.9 0.3 4e-17 62.4 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CCL98927.1 - 0.021 14.4 0.3 0.042 13.4 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HdeA PF06411.6 CCL98927.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 HdeA/HdeB family DUF3752 PF12572.3 CCL98928.1 - 2.3e-27 96.0 8.4 2.3e-27 96.0 5.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) tRNA-synt_1g PF09334.6 CCL98929.1 - 9.4e-131 436.0 0.0 1.2e-130 435.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCL98929.1 - 2e-06 26.1 0.0 0.00015 19.9 0.0 2.9 2 1 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.15 CCL98929.1 - 5.5e-06 25.9 6.0 1.5e-05 24.5 4.1 1.7 1 0 0 1 1 1 1 WHEP-TRS domain Anticodon_1 PF08264.8 CCL98929.1 - 8.2e-05 22.3 0.1 0.00023 20.9 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA C1_1 PF00130.17 CCL98929.1 - 0.23 11.2 1.9 0.65 9.7 1.3 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Uso1_p115_C PF04871.8 CCL98929.1 - 5.5 6.9 10.5 11 5.9 7.3 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region A_deaminase PF00962.17 CCL98930.1 - 4.4e-19 68.5 0.1 2e-13 49.9 0.2 2.8 2 1 0 2 2 2 2 Adenosine/AMP deaminase Chs3p PF12271.3 CCL98931.1 - 2.7e-116 387.6 22.4 3.2e-116 387.4 15.5 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Cyclin PF08613.6 CCL98932.1 - 1.5e-18 67.6 1.2 7.8e-18 65.3 0.1 2.4 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.18 CCL98932.1 - 6.6e-08 32.1 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Gly-zipper_Omp PF13488.1 CCL98933.1 - 0.054 13.1 0.3 0.08 12.5 0.2 1.3 1 0 0 1 1 1 0 Glycine zipper HBS1_N PF08938.5 CCL98933.1 - 0.058 13.5 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 HBS1 N-terminus PT-VENN PF04829.8 CCL98933.1 - 0.21 11.1 1.8 14 5.3 0.0 2.4 2 1 0 2 2 2 0 Pre-toxin domain with VENN motif SPO22 PF08631.5 CCL98934.1 - 0.00016 20.8 7.3 0.00055 19.1 0.1 3.8 4 0 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.1 CCL98934.1 - 0.017 14.7 1.2 0.48 10.1 0.9 3.2 3 1 0 3 3 3 0 TPR repeat Apc3 PF12895.2 CCL98934.1 - 0.12 12.5 5.0 0.13 12.4 1.5 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FMO-like PF00743.14 CCL98935.1 - 6.7e-36 123.5 0.0 3.3e-25 88.2 0.0 2.6 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCL98935.1 - 4.6e-15 56.2 0.0 1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCL98935.1 - 2.9e-05 24.0 0.0 0.00011 22.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCL98935.1 - 4.1e-05 22.6 0.1 0.0079 15.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 CCL98935.1 - 0.00015 21.5 0.5 0.0041 16.8 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CCL98935.1 - 0.00087 19.2 1.0 0.0029 17.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Malic_M PF03949.10 CCL98935.1 - 0.06 12.8 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain P_proprotein PF01483.15 CCL98935.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain Thi4 PF01946.12 CCL98935.1 - 0.12 11.4 0.1 3.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 CCL98935.1 - 0.75 8.6 4.4 0.62 8.9 0.4 2.6 3 1 0 3 3 3 0 FAD dependent oxidoreductase tRNA-synt_1c PF00749.16 CCL98936.1 - 2.4e-88 295.8 0.0 3.4e-88 295.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-UBR PF02207.15 CCL98937.1 - 1.3e-16 60.0 15.0 3.2e-16 58.8 10.4 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CCL98937.1 - 3.4e-11 42.6 0.0 8.1e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 CCL98937.1 - 0.061 12.5 0.0 0.16 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL TRAPP PF04051.11 CCL98938.1 - 9.8e-30 103.0 0.0 1.1e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 CCL98939.1 - 1.5e-09 37.3 0.0 0.7 9.8 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Glyco_transf_25 PF01755.12 CCL98941.1 - 1.2e-06 28.3 0.6 0.4 10.2 0.0 4.1 4 1 0 4 4 4 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Zeta_toxin PF06414.7 CCL98942.1 - 0.00013 21.1 0.2 0.0069 15.4 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 CCL98942.1 - 0.0015 19.3 0.1 0.0061 17.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCL98942.1 - 0.0016 18.2 0.1 0.042 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CCL98942.1 - 0.0052 15.5 0.0 0.0069 15.1 0.0 1.1 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 CCL98942.1 - 0.015 15.6 0.0 0.053 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCL98942.1 - 0.076 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCL98942.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain CPT PF07931.7 CCL98942.1 - 0.13 11.9 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein zf-C2H2 PF00096.21 CCL98944.1 - 1.5e-09 37.6 10.8 9.5e-05 22.5 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCL98944.1 - 8e-09 35.3 7.9 2.1e-06 27.7 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCL98944.1 - 0.00082 19.5 9.6 0.33 11.3 2.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CCL98944.1 - 0.012 15.2 1.2 0.012 15.2 0.8 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 CCL98944.1 - 0.046 13.8 2.8 3.4 7.9 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CHY PF05495.7 CCL98944.1 - 0.13 12.4 2.4 0.23 11.6 1.6 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-met PF12874.2 CCL98944.1 - 0.26 11.5 3.3 11 6.3 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCL98944.1 - 0.4 10.6 3.5 0.51 10.3 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger PSCyt3 PF07627.6 CCL98944.1 - 3.1 7.7 5.5 2 8.3 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) ARS2 PF04959.8 CCL98944.1 - 5.6 7.0 6.6 0.86 9.7 0.3 2.3 1 1 0 2 2 2 0 Arsenite-resistance protein 2 P22_Tail-4 PF11650.3 CCL98945.1 - 0.084 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor E1-E2_ATPase PF00122.15 CCL98946.1 - 1.1e-61 207.8 6.8 1.1e-61 207.8 4.7 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCL98946.1 - 7.6e-43 146.1 8.9 7.6e-43 146.1 6.2 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCL98946.1 - 6.8e-29 101.8 0.0 1.2e-27 97.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCL98946.1 - 2.2e-22 78.2 0.1 1.3e-20 72.6 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CCL98946.1 - 3.4e-19 68.5 0.0 6.3e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCL98946.1 - 6.8e-13 49.2 0.0 1.6e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCL98946.1 - 7.4e-07 28.9 0.8 3.2e-06 26.9 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCL98946.1 - 0.014 15.6 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase G8 PF10162.4 CCL98946.1 - 0.15 11.8 0.2 0.51 10.1 0.1 1.8 1 0 0 1 1 1 0 G8 domain zf-C3HC4_3 PF13920.1 CCL98947.1 - 0.58 9.8 8.8 1.1 9.0 6.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCL98947.1 - 5.1 7.2 12.1 8.8 6.4 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CBP4 PF07960.6 CCL98948.1 - 2e-08 33.9 0.0 2.3e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 CBP4 DPBB_1 PF03330.13 CCL98949.1 - 0.00059 19.7 0.0 0.0013 18.6 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DPBB_1 PF03330.13 CCL98950.1 - 1.6e-07 31.1 0.0 3.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CCL98950.1 - 0.0052 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Barwin family DUF908 PF06012.7 CCL98950.1 - 0.049 12.9 0.1 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF566 PF04484.7 CCL98950.1 - 2 7.8 18.6 2.9 7.3 12.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) RCC1 PF00415.13 CCL98952.1 - 6e-16 58.3 6.0 0.031 14.4 0.0 8.7 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCL98952.1 - 8.3e-05 22.0 26.2 0.0052 16.3 0.2 6.8 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.17 CCL98953.1 - 1.2e-25 88.9 0.0 2e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 CCL98953.1 - 1.8e-21 74.3 0.0 2.7e-05 23.3 0.0 5.6 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 CCL98953.1 - 1e-17 63.8 0.0 4.4e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL98953.1 - 7.5e-14 51.3 0.0 1e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Linker_histone PF00538.14 CCL98955.1 - 1.5e-14 53.8 0.9 2.5e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family AT_hook PF02178.14 CCL98955.1 - 0.0094 15.5 0.7 0.08 12.6 0.5 2.8 1 0 0 1 1 1 1 AT hook motif Glyco_transf_90 PF05686.7 CCL98955.1 - 0.029 13.0 0.0 0.047 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 90 Trypan_glycop PF00913.14 CCL98955.1 - 0.56 9.0 18.8 0.077 11.8 8.8 1.9 1 1 1 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) Tox-SHH PF15652.1 CCL98955.1 - 3.3 8.3 7.4 0.33 11.5 0.3 2.2 2 1 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature HTH_9 PF08221.6 CCL98956.1 - 8.5e-18 63.9 0.9 5.7e-14 51.7 0.2 3.8 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 CCL98956.1 - 1e-13 51.4 2.7 1.2e-11 44.6 0.8 2.7 2 1 0 3 3 3 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 CCL98956.1 - 8.4e-12 44.5 6.5 2.7e-08 33.2 0.1 5.4 5 1 1 6 6 6 1 TFIIE alpha subunit RPA_C PF08784.6 CCL98956.1 - 0.05 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal COX16 PF14138.1 CCL98956.1 - 5.2 7.3 10.3 1.2 9.2 1.9 2.6 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 WD40 PF00400.27 CCL98958.1 - 6.4e-09 35.3 15.0 0.007 16.2 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3312 PF11768.3 CCL98958.1 - 0.12 10.5 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Adaptin_N PF01602.15 CCL98959.1 - 2.9e-124 415.2 5.9 2.9e-124 415.2 4.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CCL98959.1 - 4.6e-37 126.4 0.0 1.4e-36 124.8 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 CCL98959.1 - 4.2e-19 68.9 0.1 8.6e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain RasGAP PF00616.14 CCL98960.1 - 2.8e-33 115.2 0.0 4e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 CCL98960.1 - 6.2e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF3329 PF11808.3 CCL98960.1 - 0.27 11.3 2.7 0.61 10.2 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3329) ELO PF01151.13 CCL98961.1 - 2.3e-62 210.5 20.1 2.9e-62 210.1 13.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1162 PF06650.7 CCL98963.1 - 3e-59 200.4 0.0 3.3e-55 187.2 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CCL98963.1 - 2.9e-31 107.4 0.0 1e-30 105.6 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 CCL98963.1 - 2.3e-06 27.6 0.0 7e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain DENN PF02141.16 CCL98964.1 - 2.2e-20 73.1 0.0 4.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain TMCO5 PF14992.1 CCL98964.1 - 0.076 12.1 7.4 0.13 11.3 5.1 1.3 1 0 0 1 1 1 0 TMCO5 family Jnk-SapK_ap_N PF09744.4 CCL98964.1 - 0.37 10.7 8.5 0.73 9.8 5.9 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6 PF04111.7 CCL98964.1 - 0.4 9.6 8.0 0.85 8.5 5.5 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4196 PF13846.1 CCL98964.1 - 0.51 10.6 8.5 0.054 13.7 1.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4196) Filament PF00038.16 CCL98964.1 - 0.92 8.9 15.1 0.064 12.7 6.6 1.8 2 0 0 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 CCL98964.1 - 1.3 9.3 13.1 4.6 7.6 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IFT57 PF10498.4 CCL98964.1 - 1.7 7.2 11.7 0.15 10.7 4.6 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TMPIT PF07851.8 CCL98964.1 - 2 7.4 3.5 3.2 6.7 2.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Enkurin PF13864.1 CCL98964.1 - 4.2 7.6 11.3 12 6.2 7.9 1.7 1 0 0 1 1 1 0 Calmodulin-binding DUF342 PF03961.8 CCL98964.1 - 7.1 4.9 5.6 12 4.1 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2229 PF09989.4 CCL98964.1 - 8.8 5.7 4.6 17 4.8 3.2 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Gemini_AC4_5_2 PF08464.5 CCL98965.1 - 0.12 12.1 0.3 0.23 11.1 0.2 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region IF4E PF01652.13 CCL98966.1 - 1.9e-48 164.1 0.0 2.4e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pil1 PF13805.1 CCL98967.1 - 2.6e-16 59.5 1.7 4.5e-16 58.8 1.2 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 DUF570 PF04489.8 CCL98967.1 - 0.1 11.0 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF570) GrpE PF01025.14 CCL98967.1 - 0.12 11.8 2.6 0.26 10.8 1.8 1.5 1 0 0 1 1 1 0 GrpE DUF972 PF06156.8 CCL98967.1 - 0.14 12.5 5.4 1.8 8.9 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Lge1 PF11488.3 CCL98967.1 - 0.83 9.8 4.4 6.1 7.1 1.9 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 AdoMet_MTase PF07757.8 CCL98968.1 - 2.4e-21 75.9 0.0 1.2e-19 70.4 0.0 2.6 1 1 1 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 CCL98968.1 - 0.00091 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCL98968.1 - 0.18 12.3 0.1 0.37 11.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain LRR_4 PF12799.2 CCL98969.1 - 0.002 17.7 0.4 0.13 11.9 0.0 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CCL98969.1 - 0.0047 16.6 0.1 0.0047 16.6 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 CCL98970.1 - 0.014 15.0 4.7 0.27 10.9 3.2 2.5 1 1 0 1 1 1 0 F-box-like PAXNEB PF05625.6 CCL98971.1 - 4.3e-53 180.4 0.0 5.6e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein IL6Ra-bind PF09240.5 CCL98971.1 - 0.009 16.1 0.5 1.9 8.7 0.0 2.3 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding Peptidase_S24 PF00717.18 CCL98972.1 - 6.6e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CCL98972.1 - 9.9e-06 25.1 0.0 0.0015 18.0 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 TPR_11 PF13414.1 CCL98973.1 - 1.5e-08 34.1 0.5 0.0096 15.5 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CCL98973.1 - 2.8e-06 26.7 0.3 0.026 14.1 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCL98973.1 - 0.00017 21.2 0.3 0.81 9.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCL98973.1 - 0.0018 18.1 0.1 0.86 9.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCL98973.1 - 0.022 14.5 0.1 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCL98973.1 - 0.11 13.2 0.5 2.8 8.7 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Snf7 PF03357.16 CCL98974.1 - 1.7e-40 138.1 21.4 2.8e-40 137.4 14.2 1.6 2 0 0 2 2 2 1 Snf7 TPR_MLP1_2 PF07926.7 CCL98974.1 - 0.14 11.9 8.5 0.29 10.8 5.8 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein YlqD PF11068.3 CCL98974.1 - 0.17 11.9 17.0 0.4 10.7 5.3 2.3 1 1 1 2 2 2 0 YlqD protein Ribosomal_L10 PF00466.15 CCL98974.1 - 0.23 11.3 3.5 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L10 V_ATPase_I PF01496.14 CCL98974.1 - 0.75 7.5 7.0 1.2 6.9 4.9 1.2 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_A_type_inc PF04508.7 CCL98974.1 - 1.1 9.2 6.3 0.74 9.7 2.3 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Resolvase PF00239.16 CCL98974.1 - 1.1 9.1 12.7 0.5 10.2 3.8 2.4 2 1 1 3 3 3 0 Resolvase, N terminal domain hDGE_amylase PF14701.1 CCL98974.1 - 1.2 7.9 4.1 1.5 7.5 2.9 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Pathogen_betaC1 PF09593.5 CCL98974.1 - 1.2 8.8 4.5 2.1 8.1 3.1 1.3 1 0 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein adh_short PF00106.20 CCL98975.1 - 3.8e-17 62.7 0.0 4.9e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCL98975.1 - 2.6e-06 27.2 0.0 1.7e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 CCL98975.1 - 0.00029 19.9 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 CCL98975.1 - 0.00044 19.7 0.0 0.0018 17.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CCL98975.1 - 0.0022 18.0 0.0 0.0056 16.7 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 CCL98975.1 - 0.0028 16.8 0.5 0.0037 16.4 0.3 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 CCL98975.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.5 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CCL98975.1 - 0.012 15.3 0.2 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 CCL98975.1 - 0.093 11.7 0.1 0.66 9.0 0.0 2.1 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-oxoacid_dh PF00198.18 CCL98976.1 - 1e-81 273.6 0.0 1.4e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCL98976.1 - 1.1e-18 66.5 1.3 3.2e-18 65.1 0.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CCL98976.1 - 1.1e-15 56.9 0.1 2.6e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain EXOSC1 PF10447.4 CCL98977.1 - 2.3e-20 72.3 0.1 3.6e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Sugar_tr PF00083.19 CCL98978.1 - 5.4e-32 110.9 32.7 8.1e-18 64.2 8.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCL98978.1 - 6.1e-15 54.7 40.9 7.7e-08 31.4 13.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 CCL98978.1 - 2.6e-05 23.1 4.1 0.044 12.4 0.2 2.3 2 0 0 2 2 2 2 BT1 family Cytomega_UL20A PF05984.7 CCL98978.1 - 0.04 14.1 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein NUDE_C PF04880.8 CCL98979.1 - 0.0026 18.1 25.0 0.0026 18.1 17.3 6.1 3 2 2 5 5 5 1 NUDE protein, C-terminal conserved region ERM PF00769.14 CCL98979.1 - 1.1 8.6 28.9 0.095 12.2 4.7 2.6 2 1 1 3 3 3 0 Ezrin/radixin/moesin family COG2 PF06148.6 CCL98979.1 - 1.9 8.3 14.7 0.029 14.2 2.6 2.9 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 CCL98979.1 - 5.6 5.9 24.7 0.27 10.2 11.4 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4407 PF14362.1 CCL98979.1 - 5.8 5.7 13.7 0.33 9.8 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Es2 PF09751.4 CCL98980.1 - 8.7e-78 262.5 1.6 1.1e-77 262.2 1.1 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Nefa_Nip30_N PF10187.4 CCL98981.1 - 5.8e-26 90.6 8.2 5.8e-26 90.6 5.7 1.8 3 0 0 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 NTP_transf_4 PF13562.1 CCL98981.1 - 0.11 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Totivirus_coat PF05518.6 CCL98981.1 - 1.8 6.2 7.6 2.4 5.9 5.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein LRR_8 PF13855.1 CCL98983.1 - 0.0099 15.6 5.0 0.28 10.9 0.3 3.5 4 0 0 4 4 4 1 Leucine rich repeat F-box-like PF12937.2 CCL98983.1 - 0.051 13.3 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like PRANC PF09372.5 CCL98983.1 - 0.17 11.8 0.0 0.91 9.5 0.0 2.2 3 0 0 3 3 3 0 PRANC domain LRR_7 PF13504.1 CCL98983.1 - 0.31 11.3 4.7 59 4.5 0.0 5.3 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 CCL98983.1 - 0.68 9.6 7.7 8 6.2 0.1 4.7 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CCL98983.1 - 1.4 9.2 4.7 70 3.9 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat AMP-binding PF00501.23 CCL98984.1 - 1.5e-25 89.5 0.0 2.6e-24 85.3 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AAA_25 PF13481.1 CCL98985.1 - 6.5e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 CCL98985.1 - 0.0012 17.7 0.0 0.014 14.3 0.0 2.1 2 0 0 2 2 2 1 Rad51 TSC22 PF01166.13 CCL98986.1 - 0.12 12.3 16.8 1.7 8.6 0.6 4.3 4 1 0 4 4 4 0 TSC-22/dip/bun family Syntaxin-6_N PF09177.6 CCL98986.1 - 2.7 8.4 16.1 2.1 8.8 0.2 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal ERM PF00769.14 CCL98986.1 - 6.1 6.2 32.7 18 4.7 22.7 1.8 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AMP-binding PF00501.23 CCL98987.1 - 1.4e-26 92.9 0.1 9.3e-26 90.1 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme SLX9 PF15341.1 CCL98987.1 - 4.4e-22 78.7 5.5 8.9e-22 77.7 3.8 1.5 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 TPT PF03151.11 CCL98987.1 - 2.6 7.6 23.0 2.5 7.7 3.6 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.15 CCL98987.1 - 5.6 7.0 31.5 0.05 13.6 2.2 3.0 3 0 0 3 3 3 0 EamA-like transporter family PPR_2 PF13041.1 CCL98988.1 - 6.5e-31 106.0 0.1 1.6e-08 34.4 0.0 6.3 6 1 1 7 7 7 5 PPR repeat family PPR PF01535.15 CCL98988.1 - 3e-21 73.8 1.2 8.9e-07 28.4 0.0 7.0 7 0 0 7 7 7 4 PPR repeat PPR_3 PF13812.1 CCL98988.1 - 2.3e-17 61.7 6.4 9.9e-05 22.3 0.0 8.1 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCL98988.1 - 1.2e-15 56.6 0.0 2.4e-05 23.7 0.0 5.9 6 0 0 6 6 6 3 PPR repeat ECSIT PF06239.6 CCL98988.1 - 0.16 10.8 0.0 9.2 5.0 0.0 2.7 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Hap4_Hap_bind PF10297.4 CCL98989.1 - 8.8e-09 34.9 3.5 1.8e-08 33.8 2.4 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 CCL98989.1 - 3.4e-05 23.6 17.9 5.6e-05 23.0 11.2 2.1 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 CCL98989.1 - 0.0032 17.2 18.1 0.024 14.4 3.7 2.5 2 0 0 2 2 2 2 Basic region leucine zipper HALZ PF02183.13 CCL98989.1 - 0.0051 16.4 0.9 0.013 15.1 0.6 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF972 PF06156.8 CCL98989.1 - 0.041 14.2 3.2 0.082 13.2 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF3361 PF11841.3 CCL98989.1 - 0.16 11.6 0.4 0.7 9.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) DUF904 PF06005.7 CCL98989.1 - 0.3 11.4 6.3 0.68 10.2 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) SLS PF14611.1 CCL98990.1 - 3.4e-09 36.4 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.7 CCL98991.1 - 2.5e-71 239.5 26.0 2.5e-71 239.5 18.1 3.5 3 1 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 CCL98991.1 - 5.5e-53 179.6 0.2 2.7e-52 177.4 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 CCL98991.1 - 3.9e-39 133.7 9.3 3.9e-39 133.7 6.4 5.4 5 2 1 6 6 6 1 Domain of unknown function (DUF3381) NRDE-2 PF08424.5 CCL98994.1 - 7.6e-53 179.4 0.1 2.2e-52 177.9 0.0 1.8 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 CCL98994.1 - 4.6e-05 23.6 0.3 1.1 9.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCL98994.1 - 6.4e-05 23.5 4.5 0.0079 16.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCL98994.1 - 0.0024 18.3 11.7 1.3 9.8 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Sec39 PF08314.6 CCL98995.1 - 6.5e-63 212.8 0.0 9.5e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 UPF0113 PF03657.8 CCL98995.1 - 1.4e-08 34.5 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Cgr1 PF03879.9 CCL98997.1 - 1.1e-12 48.0 14.2 1.4e-12 47.7 9.8 1.0 1 0 0 1 1 1 1 Cgr1 family RF-1 PF00472.15 CCL98997.1 - 0.0023 17.6 3.8 0.0028 17.4 2.7 1.2 1 0 0 1 1 1 1 RF-1 domain UPF0193 PF05250.6 CCL98997.1 - 0.003 17.1 1.4 0.0032 17.0 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) CAF-1_p150 PF11600.3 CCL98997.1 - 0.0085 15.4 10.7 0.0098 15.2 7.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Remorin_C PF03763.8 CCL98997.1 - 0.034 13.6 13.0 0.044 13.3 9.0 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region DUF4355 PF14265.1 CCL98997.1 - 0.049 13.5 10.0 0.06 13.2 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) FGF-BP1 PF06473.7 CCL98997.1 - 0.65 9.5 6.0 0.8 9.2 4.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Atg14 PF10186.4 CCL98997.1 - 0.74 8.6 5.1 0.79 8.6 3.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pep3_Vps18 PF05131.9 CCL98998.1 - 1.2e-39 135.1 0.0 2.3e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CCL98998.1 - 1.3e-06 28.0 0.3 0.00028 20.5 0.0 3.5 3 1 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CCL98998.1 - 2.3e-05 24.5 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 CCL98998.1 - 7.9e-05 22.3 3.7 8.2e-05 22.2 0.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCL98998.1 - 0.0003 20.5 1.7 0.0003 20.5 1.2 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCL98998.1 - 0.017 15.1 1.3 0.017 15.1 0.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCL98998.1 - 0.017 14.7 2.0 0.17 11.5 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCL98998.1 - 0.11 12.1 3.9 0.082 12.5 0.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1664 PF07889.7 CCL98998.1 - 0.12 12.1 0.6 2.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_UBOX PF13445.1 CCL98998.1 - 0.51 10.1 1.8 0.91 9.2 0.2 2.1 2 0 0 2 2 2 0 RING-type zinc-finger UreD PF01774.12 CCL98999.1 - 1.3e-56 191.4 0.0 1.5e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein MFS_1 PF07690.11 CCL99000.1 - 6.5e-31 107.3 26.2 8.2e-31 106.9 18.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-synt_2 PF00152.15 CCL99001.1 - 1.4e-73 247.6 0.0 1.9e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF367 PF04034.8 CCL99001.1 - 2.2e-40 137.2 0.0 4.2e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF367) LSM PF01423.17 CCL99001.1 - 1.1e-17 63.3 0.8 2e-17 62.4 0.5 1.4 1 0 0 1 1 1 1 LSM domain RLI PF04068.10 CCL99001.1 - 3.6e-11 42.4 0.0 6.6e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI tRNA_anti-codon PF01336.20 CCL99001.1 - 1.1e-08 34.8 0.1 2.1e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PPR_2 PF13041.1 CCL99002.1 - 3.2e-45 151.8 0.1 1.2e-13 50.7 0.0 12.8 11 2 3 14 14 14 9 PPR repeat family PPR PF01535.15 CCL99002.1 - 8.1e-39 128.9 3.6 3e-06 26.8 0.0 12.9 14 0 0 14 14 14 6 PPR repeat PPR_3 PF13812.1 CCL99002.1 - 2.4e-32 108.4 9.6 3e-05 23.9 0.0 14.1 14 0 0 14 14 14 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCL99002.1 - 4.7e-31 105.9 1.9 1.6e-08 33.8 0.0 10.6 13 0 0 13 13 13 4 PPR repeat TPR_14 PF13428.1 CCL99002.1 - 3.3e-11 42.7 7.3 1.8 9.4 0.1 10.3 10 1 1 11 11 11 2 Tetratricopeptide repeat RPM2 PF08579.6 CCL99002.1 - 0.0053 16.8 0.0 9.2 6.4 0.0 3.7 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) COX5A PF02284.11 CCL99002.1 - 0.024 14.6 0.0 3.5 7.6 0.0 3.3 2 1 1 3 3 3 0 Cytochrome c oxidase subunit Va B12-binding_2 PF02607.12 CCL99002.1 - 0.097 12.7 0.1 6.3 6.9 0.0 3.8 4 0 0 4 4 4 0 B12 binding domain ECSIT PF06239.6 CCL99002.1 - 0.19 10.5 0.0 14 4.4 0.0 2.8 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Thioredoxin PF00085.15 CCL99003.1 - 9.3e-48 160.2 0.0 3e-25 87.9 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CCL99003.1 - 7.9e-21 74.6 0.0 3.6e-15 56.2 0.0 2.9 2 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCL99003.1 - 1.8e-09 37.5 0.1 0.0036 17.3 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CCL99003.1 - 2e-07 31.1 3.3 2.4e-05 24.4 0.2 3.7 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CCL99003.1 - 0.00087 19.2 0.1 0.0075 16.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CCL99003.1 - 0.0045 16.7 0.0 0.38 10.6 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_9 PF14595.1 CCL99003.1 - 0.039 13.5 0.0 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Mu-like_Com PF10122.4 CCL99003.1 - 0.11 11.5 0.6 14 4.7 0.1 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com Thioredoxin_4 PF13462.1 CCL99003.1 - 0.16 11.9 0.1 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin SCO1-SenC PF02630.9 CCL99004.1 - 2.1e-53 180.5 0.0 3.2e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC CGI-121 PF08617.5 CCL99004.1 - 1.9e-35 121.9 0.0 3e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Kinase binding protein CGI-121 AhpC-TSA PF00578.16 CCL99004.1 - 3.3e-06 26.7 0.0 1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 CCL99004.1 - 0.003 17.6 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like NDUF_B7 PF05676.8 CCL99005.1 - 1.4e-30 104.5 2.8 1.6e-30 104.3 1.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 CCL99005.1 - 0.017 14.8 2.8 0.024 14.3 2.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like SR-25 PF10500.4 CCL99006.1 - 0.002 17.6 8.9 0.017 14.6 3.8 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Transformer PF06495.6 CCL99006.1 - 0.69 9.7 18.7 0.096 12.5 6.3 2.6 2 0 0 2 2 2 0 Fruit fly transformer protein CDK5_activator PF03261.10 CCL99006.1 - 5.1 6.3 8.6 7.1 5.8 6.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Suf PF05843.9 CCL99006.1 - 8.7 5.9 12.4 16 5.1 8.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Tcf25 PF04910.9 CCL99007.1 - 1.6e-71 241.1 0.2 2.8e-71 240.3 0.0 1.5 2 0 0 2 2 2 1 Transcriptional repressor TCF25 FGE-sulfatase PF03781.11 CCL99008.1 - 1.4e-21 77.0 0.7 7.8e-12 45.0 0.0 2.1 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 CCL99008.1 - 1.8e-09 38.0 0.4 2.5e-08 34.3 0.7 2.3 2 0 0 2 2 2 1 DinB superfamily p450 PF00067.17 CCL99010.1 - 3.8e-63 213.6 0.0 2.4e-62 211.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCL99011.1 - 9.8e-70 235.3 0.0 3.3e-69 233.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Pox_A3L PF05288.6 CCL99012.1 - 0.093 12.4 7.5 7.1 6.4 0.4 3.6 3 0 0 3 3 3 0 Poxvirus A3L Protein HALZ PF02183.13 CCL99012.1 - 2.3 8.0 13.4 1.4 8.6 0.0 4.3 3 1 0 3 3 3 0 Homeobox associated leucine zipper RPW8 PF05659.6 CCL99013.1 - 0.008 15.7 1.6 0.028 13.9 0.3 2.3 1 1 1 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF641 PF04859.7 CCL99013.1 - 0.013 15.2 1.0 0.013 15.2 0.7 3.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) T2SF PF00482.18 CCL99013.1 - 0.059 13.2 0.9 0.63 9.9 0.3 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Sec2p PF06428.6 CCL99013.1 - 0.97 9.3 15.1 0.34 10.7 5.9 3.4 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Reo_sigmaC PF04582.7 CCL99013.1 - 2.4 7.2 10.8 0.46 9.5 3.5 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein NYD-SP28 PF14772.1 CCL99013.1 - 3.6 7.7 16.1 2.9 8.0 2.3 4.2 4 1 0 4 4 4 0 Sperm tail Ribosomal_L4 PF00573.17 CCL99014.1 - 5.4e-63 211.8 0.0 6.6e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 CCL99015.1 - 5.9e-39 133.0 0.4 6.8e-39 132.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRCT PF00533.21 CCL99016.1 - 0.00036 20.6 0.0 0.00097 19.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AT_hook PF02178.14 CCL99016.1 - 1.3 8.9 6.1 5.8 6.9 4.2 2.2 1 0 0 1 1 1 0 AT hook motif Tim17 PF02466.14 CCL99017.1 - 5.8e-10 39.3 16.2 1.3e-09 38.1 11.3 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 CCL99017.1 - 0.0062 16.6 3.7 0.0062 16.6 2.6 2.8 2 1 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide GCN5L1 PF06320.8 CCL99019.1 - 0.059 13.1 0.0 23 4.8 0.0 2.9 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) ATXN-1_C PF12547.3 CCL99019.1 - 0.094 12.6 4.2 28 4.7 0.0 4.1 4 1 1 5 5 5 0 Capicua transcriptional repressor modulator NUC153 PF08159.7 CCL99020.1 - 3.2e-13 48.9 0.6 3.2e-13 48.9 0.4 3.8 3 1 0 3 3 3 2 NUC153 domain DUF4407 PF14362.1 CCL99020.1 - 2.6 6.9 5.8 5.3 5.9 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CS PF04969.11 CCL99021.1 - 8.1e-19 67.9 0.2 1.5e-18 67.1 0.2 1.4 1 0 0 1 1 1 1 CS domain PINIT PF14324.1 CCL99022.1 - 2.5e-36 124.9 0.1 3.7e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 CCL99022.1 - 1.4e-18 66.0 8.5 2.9e-18 65.1 5.9 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CCL99022.1 - 5.5e-07 29.0 1.4 1.3e-06 27.7 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 CCL99022.1 - 0.0021 17.5 2.4 0.018 14.5 0.1 2.9 3 0 0 3 3 3 1 SAP domain Rad50_zn_hook PF04423.9 CCL99022.1 - 0.064 12.7 0.2 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif Daxx PF03344.10 CCL99022.1 - 0.1 11.0 2.2 0.17 10.3 1.5 1.3 1 0 0 1 1 1 0 Daxx Family zf-RING_2 PF13639.1 CCL99022.1 - 0.17 11.6 6.8 0.44 10.4 4.7 1.7 1 0 0 1 1 1 0 Ring finger domain Mito_carr PF00153.22 CCL99023.1 - 7.9e-66 217.8 6.1 5.8e-24 83.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ResIII PF04851.10 CCL99024.1 - 7.2e-18 65.0 0.0 1.6e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCL99024.1 - 2.3e-15 56.4 0.0 4.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCL99024.1 - 1.8e-13 50.1 0.0 5.1e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCL99024.1 - 3e-05 22.9 0.0 7.4e-05 21.6 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2075 PF09848.4 CCL99024.1 - 0.0064 15.5 0.2 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CCL99024.1 - 0.0067 16.1 0.3 0.049 13.3 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CCL99024.1 - 0.026 14.6 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.10 CCL99024.1 - 0.029 13.7 0.0 0.073 12.4 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_11 PF13086.1 CCL99024.1 - 0.18 11.3 2.7 18 4.7 0.0 3.1 2 1 1 3 3 3 0 AAA domain Indigoidine_A PF04227.7 CCL99025.1 - 3.6e-116 387.5 0.4 5.6e-116 386.8 0.3 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 CCL99025.1 - 2.6e-22 79.3 0.0 4.5e-10 39.1 0.0 2.7 2 1 0 2 2 2 2 pfkB family carbohydrate kinase DUF4243 PF14027.1 CCL99026.1 - 4.8e-93 312.2 0.0 5.6e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) MoaE PF02391.12 CCL99028.1 - 8.3e-31 106.2 0.8 1.1e-30 105.8 0.6 1.1 1 0 0 1 1 1 1 MoaE protein Baculo_E25 PF05274.6 CCL99028.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 ICE2 PF08426.5 CCL99029.1 - 1.3e-26 93.1 23.6 2.9e-16 59.0 7.3 3.1 1 1 1 2 2 2 2 ICE2 GATase_4 PF13230.1 CCL99030.1 - 1.7e-12 46.6 0.2 2e-09 36.5 0.0 2.8 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_2 PF00310.16 CCL99030.1 - 3.8e-08 32.4 0.1 3.9e-07 29.1 0.0 2.3 2 1 1 3 3 3 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCL99030.1 - 5.4e-07 29.6 0.0 9.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain PGM_PMM_I PF02878.11 CCL99031.1 - 1.1e-17 63.8 0.1 4.6e-08 32.6 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCL99031.1 - 1.1e-13 51.4 0.0 4e-13 49.5 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCL99031.1 - 1.6e-10 40.8 0.2 5.5e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 CCL99031.1 - 0.0089 16.0 0.1 0.032 14.2 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF4614 PF15391.1 CCL99031.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SNAP PF14938.1 CCL99032.1 - 3.4e-107 357.7 16.7 3.9e-107 357.6 11.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 CCL99032.1 - 1.6e-06 27.4 10.0 0.08 12.7 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCL99032.1 - 4.2e-05 23.1 19.6 0.011 15.3 0.9 4.9 3 2 1 4 4 4 3 TPR repeat TPR_12 PF13424.1 CCL99032.1 - 0.00025 20.9 17.5 0.0003 20.6 4.4 3.8 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCL99032.1 - 0.00057 20.1 12.4 3.1 8.4 0.1 6.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCL99032.1 - 0.0015 18.3 11.0 11 6.2 0.2 6.0 6 1 0 6 6 6 1 Tetratricopeptide repeat Spatacsin_C PF14649.1 CCL99032.1 - 0.0046 15.8 5.5 0.022 13.6 2.7 2.4 1 1 1 2 2 2 1 Spatacsin C-terminus TPR_8 PF13181.1 CCL99032.1 - 0.062 13.1 8.1 0.46 10.3 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCL99032.1 - 0.82 10.4 20.9 5.9 7.6 0.4 3.9 1 1 3 4 4 4 0 Tetratricopeptide repeat NSF PF02071.15 CCL99032.1 - 3.3 8.6 18.4 2.9 8.8 0.1 6.0 5 1 0 5 5 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_14 PF13428.1 CCL99032.1 - 8.3 7.3 10.8 21 6.1 0.3 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat DUF2235 PF09994.4 CCL99034.1 - 1.6e-66 224.5 0.0 2.3e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 CCL99034.1 - 0.098 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family TRP PF06011.7 CCL99035.1 - 1.8e-05 23.5 3.7 1.8e-05 23.5 2.6 2.6 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel FMN_red PF03358.10 CCL99036.1 - 3.2e-24 85.1 0.0 5.3e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CCL99036.1 - 0.0018 17.8 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold L27 PF02828.11 CCL99036.1 - 0.073 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 L27 domain DUF947 PF06102.7 CCL99037.1 - 1.4e-37 129.1 18.7 2.1e-37 128.5 13.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF947) PEP-utilisers_N PF05524.8 CCL99037.1 - 5.2 6.8 10.6 0.24 11.2 2.1 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal CorA PF01544.13 CCL99038.1 - 6.3e-19 68.1 4.1 4.6e-09 35.7 0.3 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SR-25 PF10500.4 CCL99038.1 - 0.4 10.1 18.3 0.32 10.4 2.0 2.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DegS PF05384.6 CCL99039.1 - 0.014 14.5 5.3 0.022 13.9 3.2 1.6 1 1 0 1 1 1 0 Sensor protein DegS DUF677 PF05055.7 CCL99039.1 - 0.09 11.4 4.5 0.13 10.8 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Uso1_p115_C PF04871.8 CCL99039.1 - 0.14 12.0 5.4 0.27 11.1 3.8 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6 PF04111.7 CCL99039.1 - 1.4 7.9 8.3 2.3 7.1 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2376 PF09550.5 CCL99039.1 - 1.6 8.9 6.4 0.87 9.7 0.2 3.1 3 0 0 3 3 3 0 Conserved hypothetical phage protein (DUF2376) DUF904 PF06005.7 CCL99039.1 - 2.3 8.5 10.9 8.9 6.6 5.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Pex16 PF08610.5 CCL99040.1 - 6.8e-76 255.4 1.4 7.9e-76 255.2 1.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Cupin_2 PF07883.6 CCL99041.1 - 1.6e-05 24.3 0.0 3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.20 CCL99042.1 - 3.5e-17 62.8 0.0 6.7e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCL99042.1 - 7.7e-17 61.8 0.1 7.3e-12 45.5 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCL99042.1 - 2.3e-07 30.6 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCL99042.1 - 0.045 13.5 0.3 0.098 12.4 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase IlvN PF07991.7 CCL99043.1 - 8.6e-49 165.0 0.0 1.3e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 CCL99043.1 - 3.7e-10 40.1 0.5 8.1e-10 39.0 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CCL99043.1 - 2.7e-05 24.0 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvC PF01450.14 CCL99043.1 - 4.4e-05 23.4 0.0 7.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 CCL99043.1 - 0.00065 18.9 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CCL99043.1 - 0.0027 17.4 0.1 0.042 13.5 0.1 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 CCL99043.1 - 0.087 12.6 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RRM_1 PF00076.17 CCL99044.1 - 8.8e-40 134.1 0.2 2.3e-20 72.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL99044.1 - 5.2e-31 106.4 0.0 3.5e-15 55.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL99044.1 - 8.2e-26 89.6 0.0 1.1e-10 41.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CCL99044.1 - 5.1e-22 77.9 0.3 1.4e-21 76.5 0.2 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 CCL99044.1 - 7e-07 29.0 0.4 0.0038 17.0 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Abhydrolase_3 PF07859.8 CCL99045.1 - 2.1e-58 197.4 0.0 2.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CCL99045.1 - 5.3e-08 32.0 0.1 1.2e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CCL99045.1 - 0.00035 20.3 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCL99045.1 - 0.00045 19.5 0.0 0.0043 16.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 CCL99045.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme D-ser_dehydrat PF14031.1 CCL99046.1 - 4.1e-19 68.5 0.0 2e-18 66.3 0.0 2.2 3 0 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CCL99046.1 - 5e-12 45.8 0.1 7.1e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain zf-met PF12874.2 CCL99046.1 - 0.14 12.3 0.7 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ras PF00071.17 CCL99047.1 - 2.3e-50 170.1 0.1 1.2e-33 115.7 0.0 2.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 CCL99047.1 - 2.2e-17 63.6 0.0 4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCL99047.1 - 1.4e-09 37.4 0.0 4.2e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCL99047.1 - 1.4e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCL99047.1 - 0.00084 19.2 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase KaiC PF06745.8 CCL99047.1 - 0.003 16.7 0.1 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 CCL99047.1 - 0.0033 17.5 0.0 0.0067 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Methyltransf_25 PF13649.1 CCL99047.1 - 0.01 16.1 0.0 0.042 14.2 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain NACHT PF05729.7 CCL99047.1 - 0.036 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CCL99047.1 - 0.037 13.9 0.4 0.088 12.7 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.4 CCL99047.1 - 0.043 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 CCL99047.1 - 0.05 13.8 0.0 0.077 13.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 CCL99047.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 CCL99047.1 - 0.088 11.4 0.0 6.5 5.2 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.13 CCL99047.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.12 CCL99047.1 - 0.11 12.0 0.0 7.9 5.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.4 CCL99047.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) OppC_N PF12911.2 CCL99048.1 - 0.064 12.6 2.7 0.19 11.0 1.9 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1049 PF06305.6 CCL99048.1 - 0.12 11.8 1.3 0.21 11.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) tRNA-synt_1e PF01406.14 CCL99049.1 - 3.2e-126 420.5 0.2 3.2e-126 420.5 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CCL99049.1 - 1.2e-09 37.3 1.8 8.6e-06 24.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCL99049.1 - 3.2e-08 32.0 0.1 2.6e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 CCL99049.1 - 8.6e-05 22.7 0.0 8.6e-05 22.7 0.0 2.5 3 0 0 3 3 3 1 DALR domain GAF_2 PF13185.1 CCL99050.1 - 0.0019 18.6 0.0 0.0033 17.9 0.0 1.4 1 0 0 1 1 1 1 GAF domain GLTP PF08718.6 CCL99051.1 - 4.8e-40 137.0 0.0 6.5e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Gti1_Pac2 PF09729.4 CCL99052.1 - 2e-20 73.3 1.3 3.2e-17 62.9 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Herpes_BLLF1 PF05109.8 CCL99052.1 - 1.3 6.9 6.1 1.8 6.4 4.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) LysM PF01476.15 CCL99053.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain bZIP_2 PF07716.10 CCL99054.1 - 9.5e-10 38.1 15.0 2.3e-09 36.9 10.4 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CCL99054.1 - 1.5e-06 28.0 10.2 3.8e-06 26.7 7.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 CCL99054.1 - 0.0009 19.1 1.7 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 Haemolysin XhlA PAT1 PF09770.4 CCL99054.1 - 0.0056 15.0 26.0 0.0076 14.5 18.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Shugoshin_N PF07558.6 CCL99054.1 - 0.016 14.8 0.1 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region WD40_alt PF14077.1 CCL99054.1 - 0.062 12.9 1.4 0.12 12.0 1.0 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif TSC22 PF01166.13 CCL99054.1 - 0.11 12.5 0.5 0.29 11.1 0.4 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4106 PF13388.1 CCL99054.1 - 0.36 9.7 16.9 0.55 9.1 11.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) REC114-like PF15165.1 CCL99054.1 - 1.1 8.9 5.8 1.9 8.1 4.0 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Ndc1_Nup PF09531.5 CCL99054.1 - 1.5 7.1 8.7 2.1 6.6 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-CCCH PF00642.19 CCL99055.1 - 3.5e-09 36.1 2.5 7.6e-09 35.0 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 CCL99055.1 - 8.4e-08 31.7 5.4 1.4e-07 31.0 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCL99055.1 - 3.8e-07 29.7 7.5 6.2e-07 29.0 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCL99055.1 - 6.4e-07 29.3 9.5 1.1e-06 28.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCL99055.1 - 5.5e-06 26.0 7.1 8.8e-06 25.4 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCL99055.1 - 2.3e-05 23.9 8.3 4.1e-05 23.1 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCL99055.1 - 0.0035 17.0 4.5 0.0078 15.9 3.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCL99055.1 - 0.0091 15.8 7.0 0.02 14.7 4.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 CCL99055.1 - 0.25 10.8 1.8 0.44 10.0 1.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 CCL99055.1 - 0.44 10.6 3.6 1.3 9.1 2.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger TFIIB PF00382.14 CCL99056.1 - 4.9e-35 119.1 1.1 1.8e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CCL99056.1 - 1.4e-24 86.0 3.5 1.4e-24 86.0 2.4 2.6 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CCL99056.1 - 2.2e-07 30.0 2.3 4.9e-07 28.9 1.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 CCL99056.1 - 3.5e-07 29.8 0.9 0.0053 16.3 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.2 CCL99056.1 - 0.036 13.8 0.1 0.089 12.6 0.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 CCL99056.1 - 0.064 12.7 2.1 0.12 11.8 1.5 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain CHAT PF12770.2 CCL99057.1 - 3.9e-28 98.3 0.0 6.6e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 CCL99057.1 - 0.0095 15.8 7.4 1.2 9.1 0.1 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat DUF2841 PF11001.3 CCL99057.1 - 0.13 12.0 0.1 16 5.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2841) ubiquitin PF00240.18 CCL99058.1 - 3.5e-18 64.7 0.3 5.8e-18 64.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CCL99058.1 - 2.4e-10 39.9 0.0 7.4e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 CCL99058.1 - 2.5e-10 39.9 0.6 4.3e-10 39.1 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCL99058.1 - 1.9e-05 24.7 0.0 3.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain XPC-binding PF09280.6 CCL99058.1 - 0.019 14.4 14.3 0.053 12.9 6.7 3.3 2 1 1 3 3 3 0 XPC-binding domain RuBisCO_large_N PF02788.11 CCL99058.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Rad60-SLD_2 PF13881.1 CCL99058.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like F-box-like PF12937.2 CCL99060.1 - 7.5e-07 28.7 1.2 2e-06 27.4 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCL99060.1 - 3.5e-05 23.3 1.1 7.7e-05 22.2 0.7 1.6 1 0 0 1 1 1 1 F-box domain DUF360 PF04020.8 CCL99061.1 - 1.2 9.4 13.7 2.2 8.6 8.8 1.8 1 1 1 2 2 2 0 Membrane protein of unknown function zf-DHHC PF01529.15 CCL99061.1 - 4.4 6.6 5.3 7.4 5.9 3.6 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase RHH_4 PF13467.1 CCL99062.1 - 0.032 14.1 0.1 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain Herpes_LMP1 PF05297.6 CCL99062.1 - 0.4 9.5 3.0 0.49 9.2 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Aldo_ket_red PF00248.16 CCL99063.1 - 5e-67 225.6 0.0 8.4e-67 224.9 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family PolyA_pol_arg_C PF12626.2 CCL99063.1 - 0.075 12.6 0.8 0.15 11.6 0.5 1.5 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus DUF1722 PF08349.6 CCL99063.1 - 0.17 11.7 0.1 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) tRNA-synt_2b PF00587.20 CCL99064.1 - 8.3e-34 116.6 0.0 1.5e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCL99064.1 - 2.2e-16 59.8 8.8 2.3e-16 59.7 4.6 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Nop14 PF04147.7 CCL99065.1 - 8.5 4.1 8.9 12 3.6 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1308 PF07000.6 CCL99066.1 - 3.4e-24 85.1 0.0 8.9e-24 83.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Aldedh PF00171.17 CCL99068.1 - 7e-125 416.9 0.0 8.3e-125 416.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCL99068.1 - 0.0071 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) OmdA PF13376.1 CCL99068.1 - 0.008 15.8 0.2 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated RNA_Me_trans PF04252.8 CCL99069.1 - 2.4e-36 124.9 0.0 3.2e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Pkinase PF00069.20 CCL99070.1 - 7.3e-59 199.0 0.0 1.2e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99070.1 - 7.7e-43 146.4 0.0 1.2e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 CCL99070.1 - 1.1e-19 70.6 0.0 1.8e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 CCL99070.1 - 0.0002 20.4 0.0 0.00033 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCL99070.1 - 0.0041 16.8 0.1 0.022 14.4 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_S30 PF04758.9 CCL99071.1 - 1.9e-27 94.7 6.9 2.8e-27 94.2 4.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 TPR_16 PF13432.1 CCL99072.1 - 2.7e-10 40.6 1.9 5.2e-05 23.7 0.1 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCL99072.1 - 2.3e-09 36.7 0.7 0.00025 20.6 0.0 2.8 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 CCL99072.1 - 6.3e-08 32.5 5.3 0.029 14.9 0.2 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCL99072.1 - 4.3e-07 29.3 2.0 0.086 12.7 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCL99072.1 - 1.5e-06 28.4 4.5 0.013 15.8 0.3 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCL99072.1 - 4.1e-06 26.5 3.4 0.0012 18.6 0.2 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCL99072.1 - 6.3e-06 25.5 0.8 0.75 9.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCL99072.1 - 1.8e-05 24.5 2.5 0.0055 16.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Imm43 PF15602.1 CCL99072.1 - 0.00018 21.5 0.0 0.00039 20.4 0.0 1.6 1 1 0 1 1 1 1 Immunity protein 43 TPR_1 PF00515.23 CCL99072.1 - 0.00098 18.6 2.0 0.064 12.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCL99072.1 - 0.075 13.5 2.4 2.2 8.9 0.0 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat PPTA PF01239.17 CCL99072.1 - 0.13 11.6 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TPR_12 PF13424.1 CCL99072.1 - 1.6 8.7 4.1 6 6.8 0.0 2.8 2 1 0 3 3 3 0 Tetratricopeptide repeat ORC5_C PF14630.1 CCL99074.1 - 9e-49 166.3 0.0 1.6e-48 165.5 0.0 1.5 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus BicD PF09730.4 CCL99075.1 - 0.082 11.2 0.1 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D BCL_N PF04714.8 CCL99076.1 - 0.015 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Med7 PF05983.6 CCL99077.1 - 3e-27 95.3 0.0 3.8e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 MED7 protein U3_assoc_6 PF08640.6 CCL99077.1 - 0.059 13.1 0.5 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 HAUS4 PF14735.1 CCL99077.1 - 0.07 12.4 0.2 1.1 8.5 0.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 Asp PF00026.18 CCL99078.1 - 5.6e-43 147.3 14.1 1.2e-42 146.2 9.8 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCL99078.1 - 5e-06 26.5 4.2 6.4e-05 22.9 1.7 2.8 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCL99078.1 - 0.00029 21.2 2.6 0.015 15.7 0.4 2.8 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 CCL99078.1 - 0.017 14.6 0.2 0.08 12.4 0.2 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Pam16 PF03656.8 CCL99079.1 - 4.9e-19 68.3 0.0 3.5e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 Pam16 FliE PF02049.13 CCL99081.1 - 0.13 12.2 3.7 0.21 11.6 1.2 2.4 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE zf-U1 PF06220.7 CCL99082.1 - 2.6e-12 46.0 2.0 3.9e-12 45.5 1.4 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 CCL99082.1 - 0.49 10.6 5.5 1.6 8.9 3.8 1.8 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Chitin_synth_1 PF01644.12 CCL99083.1 - 4.5e-79 263.9 0.0 6.8e-79 263.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 CCL99083.1 - 4.9e-27 94.5 1.9 1.2e-20 73.3 0.0 2.1 1 1 1 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 CCL99083.1 - 3.6e-22 77.8 0.0 8e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 CCL99083.1 - 5.4e-10 39.2 0.1 5.4e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCL99083.1 - 2.2e-08 34.1 0.0 5.2e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 IMS PF00817.15 CCL99084.1 - 6.7e-49 165.5 0.1 1.1e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 CCL99084.1 - 1.6e-06 27.7 0.0 3.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif Rad50_zn_hook PF04423.9 CCL99085.1 - 0.034 13.6 0.1 0.074 12.5 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Amidase PF01425.16 CCL99086.1 - 4.9e-95 318.9 0.0 5.8e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Peptidase_C14 PF00656.17 CCL99087.1 - 4.2e-14 52.8 0.0 6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain APG6 PF04111.7 CCL99088.1 - 1.9e-115 385.2 3.1 2.5e-115 384.8 2.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 FtsL PF04999.8 CCL99088.1 - 0.26 11.0 4.2 0.59 9.8 2.9 1.5 1 0 0 1 1 1 0 Cell division protein FtsL V_ATPase_I PF01496.14 CCL99088.1 - 0.54 8.0 6.1 0.73 7.6 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 CCL99088.1 - 3.9 7.1 15.6 6.6 6.3 10.8 1.4 1 0 0 1 1 1 0 Mnd1 family GCS PF03074.11 CCL99089.1 - 3.1e-117 391.7 0.8 7.4e-45 153.5 0.0 3.1 1 1 1 3 3 3 3 Glutamate-cysteine ligase GCS2 PF04107.8 CCL99089.1 - 0.019 14.0 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Methyltransf_6 PF03737.10 CCL99090.1 - 5.8e-28 97.7 0.1 3e-27 95.4 0.0 1.8 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase VanZ PF04892.7 CCL99091.1 - 4.9e-07 29.7 3.0 5.4e-07 29.6 0.0 2.1 2 1 0 2 2 2 1 VanZ like family TcpE PF12648.2 CCL99091.1 - 0.022 14.9 2.2 0.034 14.2 1.5 1.4 1 0 0 1 1 1 0 TcpE family Apq12 PF12716.2 CCL99091.1 - 0.38 10.4 8.4 3.7 7.3 0.2 3.3 3 0 0 3 3 3 0 Nuclear pore assembly and biogenesis Med9 PF07544.8 CCL99092.1 - 0.0014 18.3 1.3 0.35 10.6 0.0 2.9 2 1 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.7 CCL99092.1 - 0.019 15.3 0.0 0.21 11.9 0.0 2.6 3 0 0 3 3 3 0 SlyX FlaC_arch PF05377.6 CCL99092.1 - 0.53 10.2 2.0 17 5.4 0.1 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tim17 PF02466.14 CCL99093.1 - 1.5e-30 105.8 2.1 1.9e-30 105.5 1.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-4CXXC_R1 PF10497.4 CCL99094.1 - 1.9e-15 56.8 12.8 3.6e-13 49.5 8.9 2.4 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WHIM2 PF15613.1 CCL99094.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 UPF0020 PF01170.13 CCL99095.1 - 1.6e-12 47.3 0.0 2.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CCL99095.1 - 4e-11 42.9 0.0 6.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CCL99095.1 - 0.0032 16.9 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.11 CCL99095.1 - 0.034 13.2 0.0 0.13 11.3 0.0 1.8 1 1 0 1 1 1 0 N-6 DNA Methylase DUF43 PF01861.11 CCL99095.1 - 0.065 12.2 0.0 0.4 9.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function DUF43 2OG-FeII_Oxy_2 PF13532.1 CCL99096.1 - 3e-21 76.1 0.0 3.8e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CCL99096.1 - 0.0038 17.4 0.0 0.0064 16.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP-synt_DE_N PF02823.11 CCL99098.1 - 1.7e-20 72.5 0.2 2.4e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Pyridox_oxidase PF01243.15 CCL99100.1 - 2.7e-08 33.6 0.0 3e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Aminotran_3 PF00202.16 CCL99101.1 - 1.8e-95 319.6 0.0 3.5e-95 318.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CCL99101.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase DUF155 PF02582.9 CCL99102.1 - 2.8e-55 186.9 0.1 4.4e-55 186.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2890 PF11081.3 CCL99102.1 - 0.083 12.9 0.4 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Sigma70_ner PF04546.8 CCL99102.1 - 0.45 10.0 6.1 0.76 9.3 4.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Prothymosin PF03247.9 CCL99102.1 - 1.5 8.9 15.8 2.7 8.1 10.9 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family PBP1_TM PF14812.1 CCL99102.1 - 1.7 9.0 6.7 4 7.8 4.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec5 PF15469.1 CCL99103.1 - 3.7e-57 193.0 1.9 5.5e-57 192.4 0.2 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 CCL99103.1 - 0.0075 16.0 0.1 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 SH3_7 PF12914.2 CCL99103.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain of SH3b2 type NUC153 PF08159.7 CCL99104.1 - 2.4e-13 49.4 1.0 2.4e-13 49.4 0.7 1.9 2 0 0 2 2 2 1 NUC153 domain HhH-GPD PF00730.20 CCL99105.1 - 1.1e-17 64.2 0.0 2.8e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 CCL99105.1 - 3.9e-08 32.6 0.1 4.2e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.18 CCL99105.1 - 0.011 15.3 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HemY_N PF07219.8 CCL99105.1 - 3.4 7.2 5.7 1.7 8.2 0.2 2.8 3 0 0 3 3 3 0 HemY protein N-terminus SURF4 PF02077.10 CCL99106.1 - 4e-93 311.6 5.0 4.6e-93 311.4 3.4 1.0 1 0 0 1 1 1 1 SURF4 family Cyt-b5 PF00173.23 CCL99107.1 - 2e-22 78.7 0.1 5.7e-22 77.3 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CCL99107.1 - 0.00053 20.3 9.0 0.011 16.0 4.0 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.8 CCL99108.1 - 0.00049 20.4 5.2 0.00062 20.1 3.6 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Kua-UEV1_localn PF10520.4 CCL99108.1 - 0.12 12.0 3.3 0.21 11.2 2.3 1.5 1 1 0 1 1 1 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain His_Phos_2 PF00328.17 CCL99109.1 - 5.6e-28 98.2 0.0 9e-27 94.2 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1227 PF06777.6 CCL99110.1 - 5.3e-59 198.1 0.3 9.2e-59 197.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CCL99110.1 - 7.3e-47 158.9 0.0 1.2e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CCL99110.1 - 1.1e-44 152.3 0.0 2.1e-44 151.4 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 CCL99110.1 - 0.013 14.2 0.0 0.49 9.1 0.0 2.3 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.4 CCL99110.1 - 0.15 11.0 0.1 5 5.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TPR_12 PF13424.1 CCL99111.1 - 1.3e-07 31.4 6.3 0.0094 15.8 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCL99111.1 - 0.0017 17.9 1.6 0.86 9.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCL99111.1 - 0.0031 17.2 6.2 0.09 12.7 0.1 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCL99111.1 - 0.0062 16.2 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCL99111.1 - 0.0068 16.0 0.1 4.2 7.0 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.1 CCL99111.1 - 0.02 14.6 0.3 12 5.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCL99111.1 - 0.089 13.4 11.2 2 9.2 0.6 5.4 4 3 2 6 6 6 0 Tetratricopeptide repeat DUF2225 PF09986.4 CCL99111.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 CCL99111.1 - 0.23 12.1 4.1 29 5.4 0.1 3.5 3 0 0 3 3 3 0 Sel1 repeat TPR_16 PF13432.1 CCL99111.1 - 0.74 10.5 10.5 0.11 13.1 0.5 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCL99111.1 - 0.91 10.1 2.7 6.9 7.3 0.0 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCL99111.1 - 1.1 9.2 5.4 2.3 8.2 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Peptidase_M49 PF03571.10 CCL99112.1 - 7.5e-192 638.2 0.0 9.8e-192 637.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 SpoIIE PF07228.7 CCL99113.1 - 2.3e-07 30.7 0.0 1e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CCL99113.1 - 0.032 13.6 0.0 0.25 10.7 0.0 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C Glucan_synthase PF02364.10 CCL99114.1 - 0 1352.4 0.0 0 1351.9 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCL99114.1 - 4.8e-37 126.4 0.1 1.2e-36 125.1 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RAI16-like PF10257.4 CCL99115.1 - 2.9e-71 240.2 0.5 4.7e-71 239.5 0.4 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DnaJ PF00226.26 CCL99116.1 - 2.5e-22 78.3 1.4 2.5e-22 78.3 1.0 3.0 2 1 0 2 2 2 1 DnaJ domain DUF3166 PF11365.3 CCL99116.1 - 0.0019 18.5 3.9 0.055 13.9 1.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3166) DRY_EERY PF09750.4 CCL99116.1 - 0.032 14.3 6.8 0.32 11.1 0.5 3.6 4 0 0 4 4 4 0 Alternative splicing regulator DUF805 PF05656.9 CCL99117.1 - 0.12 12.2 0.1 0.12 12.2 0.1 3.7 2 2 0 3 3 3 0 Protein of unknown function (DUF805) PsbY PF06298.6 CCL99117.1 - 1.4 8.5 6.9 0.24 10.9 1.0 2.4 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) SET PF00856.23 CCL99118.1 - 0.00079 19.7 0.0 0.0012 19.1 0.0 1.5 1 1 0 1 1 1 1 SET domain adh_short PF00106.20 CCL99119.1 - 3.6e-32 111.5 3.1 4.6e-32 111.2 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCL99119.1 - 1.2e-12 47.8 0.9 1.6e-12 47.4 0.6 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCL99119.1 - 3.7e-11 43.2 0.2 5.1e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCL99119.1 - 0.0003 20.2 0.1 0.0005 19.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CCL99119.1 - 0.00036 20.2 1.1 0.00079 19.1 0.8 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Helicase_RecD PF05127.9 CCL99119.1 - 0.0027 17.3 0.1 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Helicase THF_DHG_CYH_C PF02882.14 CCL99119.1 - 0.0063 15.6 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 CCL99119.1 - 0.036 13.2 0.1 0.056 12.6 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CCL99119.1 - 0.047 13.8 0.3 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CCL99119.1 - 0.07 12.7 1.3 0.076 12.6 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCL99119.1 - 0.55 10.2 5.0 11 5.9 3.5 2.5 1 1 0 1 1 1 0 NADH(P)-binding Zn_clus PF00172.13 CCL99121.1 - 5.4e-05 23.0 8.9 0.0001 22.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3619 PF12279.3 CCL99121.1 - 0.1 12.6 0.4 2.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) EndIII_4Fe-2S PF10576.4 CCL99121.1 - 0.3 11.3 2.5 0.61 10.3 1.7 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Aldo_ket_red PF00248.16 CCL99122.1 - 1e-49 168.8 0.0 1.2e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OTU PF02338.14 CCL99123.1 - 6.1e-16 59.1 0.0 1.2e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CCL99123.1 - 0.0013 18.1 0.0 1.5 8.0 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain AP_endonuc_2 PF01261.19 CCL99123.1 - 0.034 13.4 0.4 0.23 10.7 0.2 2.3 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Co_AT_N PF12557.3 CCL99123.1 - 0.58 10.0 5.6 1.5 8.8 3.9 1.7 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Adaptin_N PF01602.15 CCL99124.1 - 2.4e-133 445.2 5.9 3.3e-133 444.8 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCL99124.1 - 1.5e-23 83.6 0.7 1.7e-21 76.8 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCL99124.1 - 8.3e-15 54.8 8.9 1.1e-10 41.6 0.3 5.0 2 1 4 6 6 6 3 HEAT repeats HEAT PF02985.17 CCL99124.1 - 3.7e-08 32.7 7.1 0.013 15.5 0.0 5.2 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 CCL99124.1 - 1.9e-06 28.2 1.6 0.054 14.0 0.0 5.0 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.18 CCL99124.1 - 5.1e-06 26.1 3.2 0.13 12.1 0.0 5.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CCL99124.1 - 0.00033 20.0 0.1 0.0032 16.8 0.0 2.5 3 0 0 3 3 3 1 CLASP N terminal DUF4477 PF14780.1 CCL99125.1 - 1.3e-07 31.2 0.1 2e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Pyr_redox_2 PF07992.9 CCL99126.1 - 2e-09 37.6 0.0 1.6e-08 34.7 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCL99126.1 - 0.00096 18.9 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CCL99126.1 - 0.0026 17.8 0.1 1.3 9.0 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 CCL99126.1 - 0.008 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain MMR_HSR1 PF01926.18 CCL99127.1 - 6.6e-09 35.7 0.1 1e-08 35.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CCL99127.1 - 3.2e-08 32.9 0.0 4.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 CCL99127.1 - 5.5e-05 22.3 0.3 0.00026 20.2 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCL99127.1 - 0.00012 21.9 0.8 0.11 12.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Septin PF00735.13 CCL99127.1 - 0.00014 21.0 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Septin FeoB_N PF02421.13 CCL99127.1 - 0.00029 20.1 0.2 0.00065 19.0 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CCL99127.1 - 0.0049 16.0 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CCL99127.1 - 0.0062 16.6 0.1 0.016 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCL99127.1 - 0.012 15.9 0.9 0.031 14.5 0.6 1.9 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CCL99127.1 - 0.014 15.3 0.1 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 CCL99127.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CCL99127.1 - 0.034 14.2 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase CbiG_mid PF11761.3 CCL99127.1 - 0.049 13.8 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis central region SRPRB PF09439.5 CCL99127.1 - 0.054 12.7 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CCL99127.1 - 0.054 12.9 0.2 0.21 11.0 0.1 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 CCL99127.1 - 0.066 12.6 0.0 0.43 9.9 0.0 2.1 2 1 0 2 2 2 0 IstB-like ATP binding protein IIGP PF05049.8 CCL99127.1 - 0.075 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 CCL99127.1 - 0.099 13.4 0.1 0.21 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCL99127.1 - 0.12 12.2 1.1 0.36 10.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CCL99127.1 - 0.14 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cu_bind_like PF02298.12 CCL99129.1 - 0.00017 21.2 0.2 0.00044 19.9 0.2 1.7 1 0 0 1 1 1 1 Plastocyanin-like domain Methyltransf_3 PF01596.12 CCL99130.1 - 2.2e-45 154.2 0.0 2.5e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 CCL99130.1 - 5.3e-18 65.7 0.0 9.9e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCL99130.1 - 1e-11 44.6 0.0 1.7e-11 43.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCL99130.1 - 1.1e-10 42.1 0.0 1.9e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCL99130.1 - 4.5e-09 36.3 0.0 1.4e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCL99130.1 - 7.4e-08 32.1 0.0 9.9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 CCL99130.1 - 0.00041 19.7 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 CCL99130.1 - 0.0015 18.9 0.0 0.046 14.2 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CCL99130.1 - 0.012 14.7 0.0 0.028 13.4 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 CCL99130.1 - 0.025 14.1 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MSC PF09402.5 CCL99131.1 - 3.6e-49 167.2 0.0 1.8e-48 164.9 0.0 2.1 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CCL99131.1 - 1.6e-11 43.5 0.0 3.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain UEV PF05743.8 CCL99132.1 - 1.5e-30 105.4 0.0 9.4e-30 102.7 0.0 2.0 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 CCL99132.1 - 1.9e-25 88.2 0.3 1.9e-25 88.2 0.2 1.6 2 0 0 2 2 2 1 Vps23 core domain Apolipoprotein PF01442.13 CCL99132.1 - 0.097 12.1 2.1 0.14 11.6 1.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain FH2 PF02181.18 CCL99132.1 - 0.4 9.5 0.1 0.55 9.0 0.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain TEA PF01285.13 CCL99133.1 - 6.9e-09 35.3 0.8 6.9e-09 35.3 0.5 2.1 2 0 0 2 2 2 1 TEA/ATTS domain family DUF3631 PF12307.3 CCL99133.1 - 0.063 13.1 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) Apc5 PF12862.2 CCL99134.1 - 1.6e-10 40.7 0.2 6.7e-10 38.6 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 CCL99134.1 - 0.0081 16.0 2.2 5.8 6.9 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat FAD_binding_3 PF01494.14 CCL99135.1 - 3e-42 144.9 0.0 3.9e-41 141.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCL99135.1 - 1.8e-08 33.6 0.2 0.00016 20.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CCL99135.1 - 1.2e-06 27.8 0.1 1.8e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCL99135.1 - 3.6e-06 27.1 0.0 7.3e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCL99135.1 - 4.5e-06 25.8 1.3 0.00093 18.2 0.5 2.9 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCL99135.1 - 6.9e-05 21.8 1.5 0.00031 19.7 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 CCL99135.1 - 0.00031 20.8 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CCL99135.1 - 0.00082 19.7 0.2 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCL99135.1 - 0.00095 18.3 0.1 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family ThiF PF00899.16 CCL99135.1 - 0.0018 18.0 0.1 0.0034 17.2 0.1 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_8 PF13450.1 CCL99135.1 - 0.0021 18.0 0.0 0.0071 16.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCL99135.1 - 0.0025 16.3 0.2 0.01 14.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 CCL99135.1 - 0.0027 17.6 0.2 0.0052 16.6 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 CCL99135.1 - 0.0039 16.0 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase TrkA_N PF02254.13 CCL99135.1 - 0.0091 15.9 0.1 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.9 CCL99135.1 - 0.019 13.5 0.1 0.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 CCL99135.1 - 0.026 14.2 0.9 0.054 13.2 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 CCL99135.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.17 CCL99135.1 - 0.17 10.6 1.9 0.8 8.4 1.3 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A Acyltransferase PF01553.16 CCL99136.1 - 4.3e-06 26.1 0.0 3.1e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 Acyltransferase Peptidase_M24 PF00557.19 CCL99137.1 - 4e-45 153.9 0.0 5.5e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CLASP_N PF12348.3 CCL99138.1 - 2.6e-24 85.8 0.0 1.1e-08 34.7 0.0 5.6 5 0 0 5 5 5 4 CLASP N terminal HEAT_2 PF13646.1 CCL99138.1 - 5.2e-13 49.0 11.5 0.0055 16.9 0.0 8.9 8 2 1 9 9 9 3 HEAT repeats HEAT PF02985.17 CCL99138.1 - 2e-12 46.0 12.1 0.93 9.7 0.0 11.4 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 CCL99138.1 - 3.1e-05 24.3 8.1 28 5.3 0.0 8.1 6 1 1 7 7 7 0 HEAT-like repeat Acyltransferase PF01553.16 CCL99138.1 - 0.00018 20.9 0.0 0.00092 18.6 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Cnd1 PF12717.2 CCL99138.1 - 0.0013 18.6 0.0 7.4 6.3 0.0 4.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TraC_F_IV PF11130.3 CCL99138.1 - 0.0081 15.6 0.0 0.027 13.9 0.0 1.9 1 1 0 1 1 1 1 F pilus assembly Type-IV secretion system for plasmid transfer Proteasom_PSMB PF10508.4 CCL99138.1 - 0.011 13.9 0.0 0.033 12.4 0.0 1.8 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit TAN PF11640.3 CCL99138.1 - 0.054 13.2 2.2 1.6 8.4 0.1 3.9 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.15 CCL99138.1 - 0.24 9.6 1.6 21 3.2 0.0 4.2 4 1 0 4 4 4 0 Adaptin N terminal region IF-2B PF01008.12 CCL99140.1 - 8.7e-58 195.5 0.0 5.9e-57 192.8 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family UPF0086 PF01868.11 CCL99141.1 - 2.7e-21 74.9 0.0 6.8e-21 73.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function UPF0086 Cyclin_N PF00134.18 CCL99142.1 - 4.1e-05 23.1 0.2 0.00023 20.7 0.1 2.2 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCL99142.1 - 0.0064 16.4 0.1 0.048 13.5 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Ribosomal_S21 PF01165.15 CCL99144.1 - 1.1e-12 47.2 6.2 2.2e-12 46.2 4.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 Myb_Cef PF11831.3 CCL99144.1 - 0.12 11.5 0.1 0.12 11.5 0.1 1.6 2 0 0 2 2 2 0 pre-mRNA splicing factor component RWD PF05773.17 CCL99145.1 - 8.3e-17 61.1 1.1 1.2e-16 60.5 0.1 1.7 2 0 0 2 2 2 1 RWD domain NPIP PF06409.6 CCL99145.1 - 1.3 7.7 3.9 1.8 7.2 2.7 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Abhydrolase_6 PF12697.2 CCL99146.1 - 4.1e-14 53.0 0.6 6.1e-14 52.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL99146.1 - 4.5e-08 32.9 0.0 8.3e-08 32.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 CCL99146.1 - 0.071 11.5 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF915 PF06028.6 CCL99146.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) AA_permease PF00324.16 CCL99148.1 - 2.1e-126 422.0 40.8 2.6e-126 421.8 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCL99148.1 - 9.2e-33 113.4 44.3 1.3e-32 112.9 30.7 1.2 1 0 0 1 1 1 1 Amino acid permease Pirin PF02678.11 CCL99149.1 - 2.4e-31 107.7 0.3 4.6e-31 106.8 0.2 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 CCL99149.1 - 4.6e-23 81.2 0.1 2.6e-22 78.8 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Sfi1 PF08457.5 CCL99150.1 - 1.5e-31 109.4 110.1 1.4e-20 73.2 38.9 4.7 1 1 3 4 4 4 4 Sfi1 spindle body protein CLTH PF10607.4 CCL99151.1 - 1.1e-19 70.5 0.0 2.3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Med11 PF10280.4 CCL99151.1 - 0.0017 18.3 0.1 0.0057 16.6 0.1 1.8 2 0 0 2 2 2 1 Mediator complex protein DUF3858 PF12970.2 CCL99151.1 - 0.04 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) WD40 PF00400.27 CCL99152.1 - 0.03 14.2 0.4 0.098 12.5 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat MFS_1 PF07690.11 CCL99154.1 - 5.4e-26 91.1 22.1 5.4e-26 91.1 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 CCL99155.1 - 1e-77 261.3 0.0 1.7e-77 260.5 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCL99155.1 - 0.016 16.1 1.0 0.056 14.3 0.7 2.0 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain EF-hand_1 PF00036.27 CCL99156.1 - 3.2e-19 66.7 0.5 1e-05 24.4 0.0 5.0 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CCL99156.1 - 2.7e-18 64.1 0.7 8.8e-06 25.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CCL99156.1 - 4.9e-15 55.4 0.0 3.5e-08 33.4 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CCL99156.1 - 3.8e-12 44.9 0.0 0.0093 15.2 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CCL99156.1 - 1.7e-10 40.3 2.9 8e-05 22.1 0.1 4.3 4 1 1 5 5 5 4 EF-hand domain pair Proteasome PF00227.21 CCL99157.1 - 2.9e-60 202.8 0.0 4.4e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCL99157.1 - 2.9e-08 32.8 0.1 8.3e-08 31.4 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.16 CCL99158.1 - 1e-33 115.6 0.0 1.3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCL99158.1 - 6.2e-14 51.7 0.0 9.6e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CCL99158.1 - 8.1e-12 44.5 0.0 1.6e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.1 CCL99158.1 - 0.0054 16.6 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Ssu72 PF04722.8 CCL99159.1 - 1.2e-77 259.7 0.0 1.4e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein NeA_P2 PF12312.3 CCL99159.1 - 0.11 11.6 2.9 5.6 6.1 0.5 2.2 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein F-box-like PF12937.2 CCL99160.1 - 4.1e-08 32.8 0.2 1.7e-07 30.8 0.1 2.2 1 0 0 1 1 1 1 F-box-like EzrA PF06160.7 CCL99160.1 - 0.0081 14.3 0.2 0.011 13.9 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA F-box-like_2 PF13013.1 CCL99160.1 - 0.029 14.0 0.1 0.088 12.5 0.1 1.8 1 0 0 1 1 1 0 F-box-like domain IncA PF04156.9 CCL99160.1 - 0.067 12.7 0.2 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 IncA protein DUF4200 PF13863.1 CCL99160.1 - 0.18 11.7 0.6 0.28 11.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 CCL99160.1 - 0.22 9.9 0.2 0.31 9.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain LRR_7 PF13504.1 CCL99160.1 - 1.5 9.3 5.8 9.1 6.9 0.1 4.3 5 0 0 5 5 5 0 Leucine rich repeat DUF2414 PF10309.4 CCL99161.1 - 9.4e-08 31.6 0.0 2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 CCL99161.1 - 0.0015 18.9 7.9 0.0015 18.9 5.5 3.0 3 1 0 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 KH_1 PF00013.24 CCL99162.1 - 0.00014 21.4 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CCL99162.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 CCL99162.1 - 0.0059 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 KH domain Methyltransf_16 PF10294.4 CCL99165.1 - 3.7e-41 140.4 0.1 4.7e-40 136.8 0.1 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCL99165.1 - 0.0012 19.4 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCL99165.1 - 0.018 14.3 0.0 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 CCL99165.1 - 0.023 13.8 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CCL99165.1 - 0.078 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 CCL99165.1 - 0.096 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ribosomal_L12 PF00542.14 CCL99166.1 - 1.8e-18 66.2 3.7 3.7e-17 62.0 1.3 2.5 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Not3 PF04065.10 CCL99167.1 - 2.5e-94 314.9 22.0 3.6e-94 314.3 15.3 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CCL99167.1 - 1.1e-43 148.2 8.0 1.1e-43 148.2 5.5 2.6 2 1 1 3 3 3 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 CCL99167.1 - 0.011 15.6 0.9 0.044 13.7 0.7 2.0 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.20 CCL99167.1 - 2.6 8.2 14.7 2.4 8.3 5.5 2.6 1 1 1 2 2 2 0 Syntaxin SH3_1 PF00018.23 CCL99168.1 - 3.2e-24 84.0 0.0 3.8e-12 45.3 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CCL99168.1 - 2.7e-20 71.6 0.0 6.8e-09 35.1 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 CCL99168.1 - 1.5e-16 59.5 0.0 1.3e-09 37.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 CCL99168.1 - 2.4e-07 30.5 0.0 5.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 PX domain Macoilin PF09726.4 CCL99168.1 - 1.7 6.8 14.7 2.3 6.3 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein GAS2 PF02187.12 CCL99169.1 - 1.1e-08 34.7 0.0 3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain MAP7 PF05672.6 CCL99169.1 - 0.33 10.3 59.5 1 8.7 41.2 1.8 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family OTT_1508_deam PF14441.1 CCL99170.1 - 0.033 14.0 0.2 0.075 12.8 0.1 1.5 1 0 0 1 1 1 0 OTT_1508-like deaminase HR1 PF02185.11 CCL99170.1 - 0.035 13.8 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Hr1 repeat FCD PF07729.7 CCL99170.1 - 0.057 13.7 0.9 0.34 11.2 0.0 2.5 3 0 0 3 3 3 0 FCD domain Romo1 PF10247.4 CCL99171.1 - 0.093 12.9 0.1 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Aconitase PF00330.15 CCL99172.1 - 2.2e-180 600.1 0.0 2.7e-180 599.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCL99172.1 - 9.4e-40 135.7 0.0 1.6e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L29e PF01779.12 CCL99173.1 - 2.4e-21 75.2 14.7 3.6e-21 74.7 10.2 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family BBP1_N PF15271.1 CCL99173.1 - 0.069 13.5 0.8 0.073 13.4 0.5 1.0 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein Tau95 PF09734.4 CCL99174.1 - 1.1e-54 185.8 0.1 1.7e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Sld5 PF05916.6 CCL99176.1 - 0.001 19.2 0.0 0.0022 18.2 0.0 1.5 2 0 0 2 2 2 1 GINS complex protein PapC_C PF13953.1 CCL99176.1 - 0.025 14.2 0.0 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 PapC C-terminal domain Pkr1 PF08636.5 CCL99177.1 - 2.7e-15 56.1 3.2 3.5e-15 55.8 2.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Ferritin_2 PF13668.1 CCL99178.1 - 5e-36 123.6 1.4 8.6e-36 122.9 0.9 1.3 1 0 0 1 1 1 1 Ferritin-like domain KAR9 PF08580.5 CCL99178.1 - 3 6.0 12.4 4 5.6 8.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF566 PF04484.7 CCL99178.1 - 5.4 6.4 13.3 8.8 5.7 9.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Peptidase_S10 PF00450.17 CCL99179.1 - 1.3e-93 314.4 1.5 2.6e-92 310.1 1.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Nop PF01798.13 CCL99180.1 - 9.8e-59 196.9 1.1 2.3e-58 195.7 0.8 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CCL99180.1 - 1.4e-27 95.2 0.3 2.4e-27 94.5 0.2 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCL99180.1 - 5.7e-21 74.4 0.9 1.8e-20 72.8 0.1 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF1993 PF09351.5 CCL99182.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Pkinase PF00069.20 CCL99183.1 - 5.8e-10 38.7 0.0 4.8e-09 35.7 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99183.1 - 0.004 16.2 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.19 CCL99186.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CCL99186.1 - 0.00059 19.8 0.0 0.0015 18.5 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCL99186.1 - 0.011 15.8 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCL99186.1 - 0.027 14.3 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCL99186.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Latexin PF06907.7 CCL99186.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Latexin zf-CCCH_2 PF14608.1 CCL99187.1 - 4.7e-10 39.0 34.6 0.00023 21.0 1.9 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type E1-E2_ATPase PF00122.15 CCL99190.1 - 1.7e-41 141.8 8.6 1.7e-41 141.8 5.9 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCL99190.1 - 3.7e-21 76.5 0.1 2.6e-20 73.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CCL99190.1 - 2.5e-16 59.7 3.3 2.5e-16 59.7 2.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 CCL99190.1 - 8e-11 41.2 0.0 1.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CCL99190.1 - 2.6e-09 37.5 0.1 1.2e-08 35.3 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCL99190.1 - 9.4e-08 31.9 0.0 5.4e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCL99190.1 - 0.00037 20.1 0.0 0.0057 16.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Spore_III_AF PF09581.5 CCL99191.1 - 0.0048 16.7 1.1 0.0071 16.2 0.8 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) Vps39_2 PF10367.4 CCL99191.1 - 0.031 14.4 1.0 0.079 13.1 0.7 1.7 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 WASH-7_mid PF14744.1 CCL99191.1 - 0.052 12.3 1.5 0.073 11.9 1.0 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 DDE_Tnp_IS240 PF13610.1 CCL99191.1 - 0.12 12.3 0.7 0.26 11.2 0.3 1.7 1 1 0 1 1 1 0 DDE domain Fib_alpha PF08702.5 CCL99191.1 - 0.31 11.1 7.3 0.91 9.6 4.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SWIB PF02201.13 CCL99192.1 - 1.4e-23 82.3 0.1 2.4e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_60s PF00428.14 CCL99192.1 - 0.00035 20.8 8.0 0.00035 20.8 5.6 2.9 2 1 0 3 3 3 1 60s Acidic ribosomal protein DEK_C PF08766.6 CCL99192.1 - 0.0037 17.0 0.4 0.012 15.3 0.3 1.9 1 1 0 1 1 1 1 DEK C terminal domain ATP11 PF06644.6 CCL99192.1 - 0.02 14.4 0.2 0.02 14.4 0.1 2.0 1 1 1 2 2 2 0 ATP11 protein Myc_N PF01056.13 CCL99192.1 - 6 5.9 10.7 10 5.1 7.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF2890 PF11081.3 CCL99192.1 - 8.2 6.4 23.1 8.6 6.3 15.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) PPTA PF01239.17 CCL99193.1 - 7.5e-06 25.0 11.1 1.3 8.4 4.3 5.3 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat Ank_4 PF13637.1 CCL99194.1 - 0.041 14.4 6.6 1.5 9.4 0.0 5.0 6 1 1 7 7 7 0 Ankyrin repeats (many copies) SAP PF02037.22 CCL99194.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 SAP domain HI0933_like PF03486.9 CCL99194.1 - 0.078 11.4 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Ank_2 PF12796.2 CCL99194.1 - 0.1 12.9 0.0 0.47 10.8 0.0 2.2 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCL99194.1 - 0.26 11.5 4.7 6.4 7.1 0.0 4.6 5 1 1 6 6 6 0 Ankyrin repeats (many copies) MA3 PF02847.12 CCL99196.1 - 0.00094 18.8 0.1 0.005 16.5 0.0 2.1 2 0 0 2 2 2 1 MA3 domain DUF1917 PF08939.5 CCL99197.1 - 2.7e-19 69.8 0.8 2.7e-19 69.8 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) DUF2344 PF10105.4 CCL99197.1 - 5.5 6.4 7.2 0.46 9.9 1.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Lyase_aromatic PF00221.14 CCL99198.1 - 1e-154 515.5 2.9 1.3e-154 515.1 2.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase DAO PF01266.19 CCL99199.1 - 3.4e-46 157.7 0.1 4e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCL99199.1 - 1.7e-06 28.2 0.0 0.00058 19.9 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCL99199.1 - 1.8e-06 27.8 0.0 4.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCL99199.1 - 0.00097 18.0 0.3 0.0093 14.8 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 CCL99199.1 - 0.0014 18.4 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 CCL99199.1 - 0.0015 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding ThiF PF00899.16 CCL99199.1 - 0.0041 16.9 0.1 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 CCL99199.1 - 0.0049 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 CCL99199.1 - 0.0069 14.9 0.0 1.6 7.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 CCL99199.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 CCL99199.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Amino_oxidase PF01593.19 CCL99199.1 - 0.047 12.7 0.1 5.8 5.8 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 CCL99199.1 - 0.059 13.7 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCL99199.1 - 0.063 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 CCL99199.1 - 0.087 11.6 0.1 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A CPSase_L_D2 PF02786.12 CCL99200.1 - 6.6e-107 355.5 0.0 5.3e-83 277.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CCL99200.1 - 1.1e-40 138.1 0.2 2.5e-40 137.0 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 CCL99200.1 - 8e-37 125.7 0.0 1.9e-18 66.5 0.0 2.8 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CCL99200.1 - 8.3e-37 126.6 0.1 7.4e-19 68.1 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCL99200.1 - 7.9e-21 74.1 0.0 2.2e-09 36.5 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CCL99200.1 - 1.1e-16 60.7 0.0 3.3e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCL99200.1 - 6.2e-12 45.3 0.0 6.8e-05 22.3 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 CCL99200.1 - 2.9e-07 30.1 0.0 0.0074 15.7 0.0 2.8 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 CCL99200.1 - 1.8e-05 24.0 0.0 0.027 13.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 CCL99200.1 - 2.8e-05 24.0 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 CCL99200.1 - 0.073 12.6 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HLH PF00010.21 CCL99202.1 - 7.3e-09 35.1 0.0 7.3e-09 35.1 0.0 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain AA_permease_2 PF13520.1 CCL99204.1 - 1.5e-46 158.8 46.5 3.5e-43 147.7 21.0 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 CCL99204.1 - 2.8e-14 52.3 41.8 3.1e-13 48.9 28.9 2.1 1 1 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 CCL99205.1 - 2.7e-20 72.3 46.2 2.7e-15 55.9 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CCL99205.1 - 0.017 15.1 0.3 0.017 15.1 0.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 CCL99206.1 - 3.6e-21 75.2 44.4 4.6e-15 55.1 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CCL99206.1 - 0.035 14.1 0.3 0.035 14.1 0.2 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1228) RRM_1 PF00076.17 CCL99207.1 - 2.5e-12 46.2 0.0 4.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL99207.1 - 1.4e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL99207.1 - 6.3e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CCL99207.1 - 0.0022 18.3 0.3 0.0052 17.1 0.2 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 6PF2K PF01591.13 CCL99208.1 - 6e-64 215.1 0.0 9.3e-64 214.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCL99208.1 - 8.6e-24 84.4 0.0 1.6e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCL99208.1 - 8.3e-08 32.2 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCL99208.1 - 0.00064 19.0 0.0 0.0012 18.1 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CCL99208.1 - 0.0012 19.6 1.0 0.0053 17.5 0.2 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCL99208.1 - 0.033 13.2 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Toprim_3 PF13362.1 CCL99208.1 - 0.082 13.1 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 Toprim domain APS_kinase PF01583.15 CCL99208.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Transp_cyt_pur PF02133.10 CCL99209.1 - 5e-123 410.9 44.4 1.1e-90 304.3 19.7 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin CLTH PF10607.4 CCL99210.1 - 4.9e-30 104.1 0.1 8.3e-30 103.3 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 CCL99210.1 - 0.0034 17.0 0.1 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger DNA_ligase_ZBD PF03119.11 CCL99210.1 - 0.068 12.8 0.7 0.19 11.4 0.5 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Nup96 PF12110.3 CCL99212.1 - 1.6e-71 240.7 0.0 2.2e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Rep_fac-A_3 PF08661.6 CCL99212.1 - 1.5e-12 47.4 0.2 4.4e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Replication factor A protein 3 DUF3455 PF11937.3 CCL99212.1 - 1.2e-08 35.0 0.0 2.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) BUD22 PF09073.5 CCL99212.1 - 5.1 6.0 13.5 8.2 5.3 9.4 1.2 1 0 0 1 1 1 0 BUD22 PIG-L PF02585.12 CCL99213.1 - 8.1e-20 71.6 0.0 1.2e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1770 PF08589.5 CCL99214.1 - 1.9e-05 25.1 0.0 2.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF706 PF05153.10 CCL99215.1 - 1.1e-128 427.9 0.5 1.3e-128 427.5 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 CCL99215.1 - 0.0032 17.4 0.0 0.26 11.2 0.0 2.8 3 0 0 3 3 3 1 HD domain Cullin_binding PF03556.10 CCL99215.1 - 0.039 14.0 0.4 6.7 6.8 0.2 2.4 1 1 1 2 2 2 0 Cullin binding tRNA-synt_1d PF00750.14 CCL99216.1 - 1.7e-85 286.9 2.1 2.2e-85 286.5 1.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CCL99216.1 - 1.9e-18 66.5 0.0 3.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain DUF2250 PF10007.4 CCL99216.1 - 0.044 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DALR_2 PF09190.6 CCL99216.1 - 0.11 12.7 0.3 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 DALR domain DUF2009 PF09418.5 CCL99217.1 - 7.5e-189 628.2 0.0 8.7e-189 628.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 CCL99217.1 - 1.3e-05 24.9 5.5 2.7e-05 23.9 3.8 1.5 1 0 0 1 1 1 1 B-box zinc finger COesterase PF00135.23 CCL99218.1 - 1.4e-81 274.8 0.0 1.4e-77 261.6 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CCL99218.1 - 2.2e-05 24.1 0.0 4.6e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCL99218.1 - 2.9e-05 23.4 0.0 4.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pro-kuma_activ PF09286.6 CCL99219.1 - 1.9e-19 70.1 0.1 5e-18 65.5 0.0 2.3 1 1 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCL99219.1 - 0.00014 21.1 0.1 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 CCL99220.1 - 1.6e-35 122.2 0.0 2.5e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCL99220.1 - 2.5e-11 43.2 0.3 4.4e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 CCL99221.1 - 1.7e-19 70.2 0.4 5.2e-18 65.4 0.1 2.9 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCL99221.1 - 1.5e-11 43.9 3.3 2.8e-11 43.0 2.2 1.5 1 1 0 1 1 1 1 Subtilase family YCII PF03795.9 CCL99222.1 - 4.2e-10 39.7 0.0 5.2e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Acetyltransf_1 PF00583.19 CCL99223.1 - 2.3e-06 27.5 0.0 4.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CCL99223.1 - 0.00074 19.4 0.0 0.003 17.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCL99223.1 - 0.0012 18.5 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 CCL99223.1 - 0.0031 17.3 0.1 0.02 14.7 0.0 2.2 2 1 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 CCL99223.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCL99223.1 - 0.017 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCL99223.1 - 0.018 15.2 0.1 0.044 13.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 CCL99224.1 - 9e-11 42.0 1.4 1.3e-10 41.5 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL99224.1 - 1.2e-08 34.7 0.0 4e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1622 PF07784.6 CCL99224.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) An_peroxidase PF03098.10 CCL99225.1 - 1e-70 238.6 0.0 1.5e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 CCL99225.1 - 6.9e-16 57.8 0.0 1.1e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 LINES_C PF14695.1 CCL99225.1 - 0.0071 15.5 0.1 0.015 14.5 0.1 1.5 1 0 0 1 1 1 1 Lines C-terminus Amidase PF01425.16 CCL99226.1 - 7.2e-33 114.0 1.7 9.5e-33 113.7 0.6 1.5 2 0 0 2 2 2 1 Amidase SUR7 PF06687.7 CCL99227.1 - 6.4e-12 45.4 18.5 8.8e-12 45.0 12.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Corona_S2 PF01601.11 CCL99227.1 - 0.12 10.4 5.8 0.19 9.8 4.0 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Abhydrolase_3 PF07859.8 CCL99228.1 - 1.3e-39 136.0 0.1 8.1e-32 110.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CCL99228.1 - 4.7e-12 45.2 0.0 1.4e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCL99228.1 - 0.00046 19.9 0.0 0.00081 19.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CCL99228.1 - 0.012 14.3 0.7 0.13 10.9 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family Arginase PF00491.16 CCL99229.1 - 2.6e-66 223.7 0.3 7.8e-66 222.2 0.2 1.6 1 1 0 1 1 1 1 Arginase family CMAS PF02353.15 CCL99230.1 - 5.7e-46 156.8 0.2 9.8e-46 156.0 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CCL99230.1 - 1.1e-06 28.4 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCL99230.1 - 0.00032 21.2 0.0 0.00065 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCL99230.1 - 0.0043 17.5 0.0 0.0091 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain An_peroxidase PF03098.10 CCL99231.1 - 4.9e-66 223.1 0.0 3.3e-65 220.4 0.0 1.9 2 0 0 2 2 2 1 Animal haem peroxidase p450 PF00067.17 CCL99231.1 - 7.2e-25 87.4 0.0 1.2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AAA_17 PF13207.1 CCL99232.1 - 0.00012 22.8 0.1 0.00034 21.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 CCL99232.1 - 0.0019 17.2 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 CCL99232.1 - 0.0053 16.7 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CCL99232.1 - 0.022 15.0 0.0 0.05 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCL99232.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CCL99232.1 - 0.074 12.6 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CCL99232.1 - 0.097 12.3 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 CCL99232.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Mg_chelatase PF01078.16 CCL99232.1 - 0.15 11.1 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rer1 PF03248.8 CCL99233.1 - 4.2e-77 257.7 1.9 4.7e-77 257.5 1.3 1.0 1 0 0 1 1 1 1 Rer1 family EI24 PF07264.6 CCL99233.1 - 5.4e-05 22.7 3.0 6.9e-05 22.3 2.1 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ABC2_membrane_4 PF12730.2 CCL99233.1 - 0.0018 17.4 1.0 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein PqqD PF05402.7 CCL99234.1 - 0.0084 16.1 0.2 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) DSBA PF01323.15 CCL99234.1 - 0.0088 15.6 0.3 0.016 14.7 0.1 1.4 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Arg_repressor PF01316.16 CCL99234.1 - 0.041 13.4 0.4 0.73 9.4 0.1 2.2 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain CorA PF01544.13 CCL99234.1 - 0.068 12.1 0.1 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Not3 PF04065.10 CCL99234.1 - 0.072 12.3 0.3 0.08 12.2 0.2 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Adeno_PIX PF03955.9 CCL99234.1 - 1.4 9.4 5.0 16 6.0 3.4 2.1 1 1 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Steroid_dh PF02544.11 CCL99235.1 - 8.1e-30 103.5 5.5 4.3e-27 94.7 3.8 3.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CCL99235.1 - 1.4e-05 24.5 1.6 0.00023 20.5 1.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1746 PF08508.5 CCL99235.1 - 0.11 12.4 0.5 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Gryzun PF07919.7 CCL99236.1 - 1.5e-54 185.2 0.0 1.9e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 CCL99236.1 - 5.6e-48 163.5 1.9 2.5e-46 158.1 1.3 2.5 1 1 0 1 1 1 1 Foie gras liver health family 1 TPR_12 PF13424.1 CCL99236.1 - 2.8e-06 27.1 0.3 0.00072 19.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCL99236.1 - 0.0058 16.1 0.3 0.049 13.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Gryzun-like PF12742.2 CCL99236.1 - 0.0084 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TPR_7 PF13176.1 CCL99236.1 - 0.02 14.6 1.8 0.048 13.4 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCL99236.1 - 0.061 13.7 0.2 0.39 11.2 0.1 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCL99236.1 - 0.082 12.8 0.0 0.082 12.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCL99236.1 - 0.13 12.1 0.0 0.43 10.4 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCL99236.1 - 0.57 9.8 0.0 0.57 9.8 0.0 3.4 4 0 0 4 4 4 0 TPR repeat Aldo_ket_red PF00248.16 CCL99237.1 - 1.7e-73 246.9 0.0 1.9e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hexapep PF00132.19 CCL99238.1 - 5.1e-11 41.5 19.1 1e-07 31.1 1.7 4.2 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCL99238.1 - 3.7e-07 29.5 13.8 3.5e-06 26.4 2.4 3.7 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 CCL99238.1 - 0.027 13.0 0.1 0.043 12.3 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase FMN_dh PF01070.13 CCL99240.1 - 6.8e-119 396.8 0.1 8.4e-119 396.5 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCL99240.1 - 1e-21 76.4 0.0 2.2e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CCL99240.1 - 6.3e-05 22.0 0.0 9.5e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CCL99240.1 - 0.00053 18.9 0.0 0.00086 18.2 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PEP_mutase PF13714.1 CCL99241.1 - 3.3e-48 163.9 3.1 3.9e-48 163.7 2.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 CCL99241.1 - 4.1e-20 71.4 0.6 5.6e-20 71.0 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family TIM-br_sig_trns PF09370.5 CCL99241.1 - 0.049 12.6 0.1 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 TIM-barrel signal transduction protein FMN_dh PF01070.13 CCL99242.1 - 7.5e-124 413.1 0.1 9.3e-124 412.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCL99242.1 - 1.6e-21 75.8 0.0 3e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 CCL99242.1 - 1.1e-05 24.4 0.3 0.00011 21.1 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CCL99242.1 - 0.0001 21.3 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 CCL99242.1 - 0.0031 16.6 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 CCL99242.1 - 0.055 12.6 0.1 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase TrkH PF02386.11 CCL99243.1 - 2.9e-94 315.5 18.8 8.3e-93 310.7 5.8 2.1 2 0 0 2 2 2 2 Cation transport protein Arrestin_N PF00339.24 CCL99244.1 - 1.1e-11 44.7 0.0 8.5e-09 35.3 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCL99244.1 - 5.4e-11 42.7 0.0 3.5e-09 36.8 0.0 3.1 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain PTH2 PF01981.11 CCL99245.1 - 0.0043 16.7 0.0 0.008 15.8 0.0 1.4 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 GST_N_3 PF13417.1 CCL99246.1 - 6.9e-26 90.2 0.0 1.6e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCL99246.1 - 7.2e-18 64.3 0.0 1.9e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCL99246.1 - 9.7e-08 32.0 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCL99246.1 - 2.2e-07 30.6 3.2 2.8e-07 30.3 1.6 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCL99246.1 - 0.0069 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCL99246.1 - 0.051 14.0 0.2 0.11 12.9 0.1 1.7 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Tim17 PF02466.14 CCL99247.1 - 7.5e-33 113.3 7.2 9.6e-33 112.9 5.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 CCL99247.1 - 0.0085 16.0 0.7 0.047 13.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF543) LCM PF04072.9 CCL99248.1 - 1.5e-25 89.8 0.0 2.2e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Amidohydro_1 PF01979.15 CCL99249.1 - 8.5e-37 127.5 0.7 1e-36 127.2 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CCL99249.1 - 1.3e-13 51.6 0.1 6.3e-12 46.0 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 CCL99249.1 - 2.1e-13 49.8 0.4 2.7e-12 46.3 0.0 2.8 2 1 1 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 CCL99249.1 - 2.1e-10 40.4 0.4 2.7e-08 33.4 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family HSP70 PF00012.15 CCL99250.1 - 2.3e-263 874.6 13.6 2.7e-263 874.3 9.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCL99250.1 - 1.2e-15 56.9 2.4 1.2e-13 50.3 0.6 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CCL99250.1 - 0.012 15.4 11.7 1.4 8.8 0.0 4.8 4 1 0 4 4 4 0 Cell division protein FtsA APH PF01636.18 CCL99251.1 - 1.1e-32 113.6 0.0 1.8e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CCL99251.1 - 0.0012 18.0 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 CCL99251.1 - 0.002 17.7 0.0 0.0078 15.8 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase HET PF06985.6 CCL99252.1 - 1e-28 100.2 0.0 2.1e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.26 CCL99253.1 - 2.7e-07 30.5 0.0 5.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 CCL99254.1 - 5.2e-05 22.8 0.2 5.2e-05 22.8 0.2 3.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 CCL99254.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.5 3 0 0 3 3 3 0 F-box domain WD40 PF00400.27 CCL99255.1 - 6.6e-13 47.9 0.2 7.5e-05 22.4 0.0 4.6 5 1 0 5 5 5 2 WD domain, G-beta repeat Gmad1 PF10647.4 CCL99255.1 - 0.002 17.5 0.0 0.0068 15.8 0.0 1.9 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 CCL99255.1 - 0.034 12.4 0.0 0.042 12.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain PQQ_2 PF13360.1 CCL99255.1 - 0.048 13.1 0.0 0.069 12.5 0.0 1.4 1 1 0 1 1 1 0 PQQ-like domain DUF3312 PF11768.3 CCL99255.1 - 0.054 11.7 0.0 0.07 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) AMPKBI PF04739.10 CCL99256.1 - 1e-18 67.0 0.1 1.3e-15 57.0 0.0 2.8 2 0 0 2 2 2 2 5'-AMP-activated protein kinase beta subunit, interation domain Nbl1_Borealin_N PF10444.4 CCL99257.1 - 3.7e-10 39.0 1.1 7.2e-10 38.0 0.8 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal MogR_DNAbind PF12181.3 CCL99257.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) POP1 PF06978.6 CCL99258.1 - 5.7e-48 163.0 17.3 1.4e-26 93.3 1.6 2.8 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CCL99258.1 - 4.8e-27 93.6 1.6 7.4e-27 93.0 0.1 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.16 CCL99258.1 - 0.021 14.2 0.0 0.24 10.7 0.0 2.7 4 0 0 4 4 4 0 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCL99258.1 - 0.062 13.3 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Filo_VP35 PF02097.10 CCL99259.1 - 0.034 13.3 0.5 0.046 12.9 0.3 1.1 1 0 0 1 1 1 0 Filoviridae VP35 Spore_YpjB PF09577.5 CCL99259.1 - 0.044 13.3 0.1 0.055 13.0 0.1 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) D123 PF07065.9 CCL99260.1 - 7.6e-74 248.4 0.0 8.9e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 D123 VWA_2 PF13519.1 CCL99262.1 - 3e-11 43.7 0.0 5.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CCL99262.1 - 1e-05 25.3 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Miro PF08477.8 CCL99263.1 - 3e-36 124.5 0.0 3.8e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 CCL99263.1 - 3.8e-35 119.4 0.0 8.1e-35 118.4 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 CCL99263.1 - 9.7e-32 108.0 0.2 2e-31 107.0 0.1 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 CCL99263.1 - 2.4e-31 108.2 0.0 1.9e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 Ras family Arf PF00025.16 CCL99263.1 - 1.2e-13 50.7 0.0 1.5e-06 27.5 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family EF-hand_6 PF13405.1 CCL99263.1 - 1e-09 37.4 0.9 0.0015 18.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.18 CCL99263.1 - 5.8e-09 35.9 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 CCL99263.1 - 1.7e-08 33.1 4.9 0.0012 18.0 0.0 2.9 3 0 0 3 3 2 2 EF hand EF-hand_7 PF13499.1 CCL99263.1 - 1.7e-07 31.3 0.2 0.025 14.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.1 CCL99263.1 - 2e-07 31.2 0.0 0.019 15.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCL99263.1 - 5.4e-07 29.7 0.0 0.031 14.2 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain MobB PF03205.9 CCL99263.1 - 7.2e-07 28.9 0.1 0.017 14.8 0.0 2.3 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_5 PF13202.1 CCL99263.1 - 8e-06 24.9 6.9 0.0009 18.4 0.1 2.7 2 0 0 2 2 2 2 EF hand AAA_18 PF13238.1 CCL99263.1 - 2.1e-05 24.8 0.0 0.35 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCL99263.1 - 3.5e-05 23.2 0.0 0.042 13.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 CCL99263.1 - 5e-05 23.0 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 CCL99263.1 - 5.4e-05 23.9 0.1 0.08 13.7 0.0 3.5 3 1 0 3 3 3 1 AAA domain SRPRB PF09439.5 CCL99263.1 - 6.1e-05 22.3 0.1 0.032 13.4 0.0 2.7 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA PF00004.24 CCL99263.1 - 6.4e-05 23.1 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 CCL99263.1 - 6.5e-05 22.0 0.0 0.04 12.9 0.0 2.3 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 CCL99263.1 - 0.0001 21.5 0.0 0.014 14.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 CCL99263.1 - 0.00012 22.0 0.0 0.17 11.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.22 CCL99263.1 - 0.00012 22.3 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 CCL99263.1 - 0.00017 21.2 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain EF-hand_10 PF14788.1 CCL99263.1 - 0.00025 20.6 3.3 0.017 14.7 0.1 2.5 2 0 0 2 2 2 1 EF hand AAA_33 PF13671.1 CCL99263.1 - 0.00028 20.7 0.0 0.48 10.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 CCL99263.1 - 0.00032 20.3 1.0 1.9 7.9 0.0 4.0 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CCL99263.1 - 0.00044 19.7 0.0 0.086 12.3 0.0 2.7 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CCL99263.1 - 0.00049 20.2 0.0 0.74 10.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase G-alpha PF00503.15 CCL99263.1 - 0.00074 18.3 0.0 0.24 10.0 0.0 2.9 3 0 0 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.18 CCL99263.1 - 0.00086 19.1 0.7 11 5.8 0.0 3.3 2 1 0 3 3 3 0 Dynamin family EF-hand_8 PF13833.1 CCL99263.1 - 0.001 18.6 0.5 0.42 10.2 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair FtsK_SpoIIIE PF01580.13 CCL99263.1 - 0.0019 17.6 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF815 PF05673.8 CCL99263.1 - 0.0022 16.9 0.0 0.23 10.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 CCL99263.1 - 0.0039 16.7 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase GTP_EFTU PF00009.22 CCL99263.1 - 0.0059 16.0 0.2 2.4 7.5 0.0 3.6 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 CCL99263.1 - 0.0078 15.9 0.0 0.35 10.5 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_21 PF13304.1 CCL99263.1 - 0.011 15.7 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 CCL99263.1 - 0.013 14.9 0.1 1.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E AAA_5 PF07728.9 CCL99263.1 - 0.013 15.2 0.0 0.54 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 CCL99263.1 - 0.014 14.2 0.0 2.9 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 CCL99263.1 - 0.017 15.4 0.2 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CCL99263.1 - 0.017 14.9 0.0 8.2 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain SPARC_Ca_bdg PF10591.4 CCL99263.1 - 0.018 15.0 2.2 0.6 10.1 0.0 2.8 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region MCM PF00493.18 CCL99263.1 - 0.02 13.7 0.0 0.055 12.2 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family TrwB_AAD_bind PF10412.4 CCL99263.1 - 0.021 13.4 0.0 2.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 CCL99263.1 - 0.023 14.1 0.0 1.4 8.3 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 CCL99263.1 - 0.026 13.6 0.0 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 CCL99263.1 - 0.031 13.6 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CCL99263.1 - 0.039 13.4 0.0 0.068 12.6 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 CCL99263.1 - 0.066 12.7 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CCL99263.1 - 0.081 12.3 0.0 1.2 8.6 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain Gtr1_RagA PF04670.7 CCL99263.1 - 0.1 11.7 0.1 9.1 5.3 0.0 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AIG1 PF04548.11 CCL99263.1 - 0.1 11.7 0.0 0.42 9.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family UPF0079 PF02367.12 CCL99263.1 - 0.11 12.1 0.0 8.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Guanylate_kin PF00625.16 CCL99263.1 - 0.14 11.5 0.0 0.42 10.0 0.0 1.8 1 0 0 1 1 1 0 Guanylate kinase IstB_IS21 PF01695.12 CCL99263.1 - 0.16 11.3 0.0 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein F-box PF00646.28 CCL99264.1 - 0.0018 17.8 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCL99264.1 - 0.0056 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like PIG-U PF06728.8 CCL99265.1 - 1e-89 301.0 32.4 1.2e-89 300.8 22.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Cyclin_N PF00134.18 CCL99266.1 - 5.3e-12 45.4 0.0 5e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCL99266.1 - 0.031 14.1 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 Cyclin, C-terminal domain Sigma70_r4_2 PF08281.7 CCL99266.1 - 0.1 12.0 0.5 64 3.1 0.1 3.9 4 0 0 4 4 4 0 Sigma-70, region 4 RasGEF PF00617.14 CCL99267.1 - 8.2e-47 159.3 0.0 1.4e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCL99267.1 - 2.2e-21 75.9 0.0 6.5e-21 74.3 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 CCL99267.1 - 2.3e-14 52.7 0.0 4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCL99267.1 - 4.1e-12 45.4 0.0 9.8e-12 44.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCL99267.1 - 1.1e-09 37.5 0.0 2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain GATA PF00320.22 CCL99268.1 - 1.6e-14 52.9 5.0 3e-14 52.0 3.4 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 CCL99268.1 - 0.0032 17.2 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold Ins_P5_2-kin PF06090.7 CCL99271.1 - 3.1e-50 170.9 0.0 3.7e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Zn_clus PF00172.13 CCL99272.1 - 4e-08 33.0 10.9 6.7e-08 32.3 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 CCL99273.1 - 9.8e-42 142.5 0.0 2.3e-41 141.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CCL99273.1 - 2.5e-37 127.9 0.0 5.3e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CCL99273.1 - 1.3e-17 63.0 0.1 2.7e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CCL99273.1 - 8e-13 48.7 0.1 2.4e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain FAD_binding_3 PF01494.14 CCL99274.1 - 1.2e-16 60.7 0.1 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCL99274.1 - 1.1e-11 44.2 6.6 2.6e-07 29.9 1.3 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCL99274.1 - 6.5e-09 35.1 0.1 1.3e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCL99274.1 - 3.7e-08 33.2 0.1 9.5e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCL99274.1 - 1.6e-06 28.1 0.3 0.00039 20.3 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCL99274.1 - 6.4e-06 26.4 0.3 0.0044 17.3 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCL99274.1 - 1.4e-05 23.7 0.4 0.00032 19.3 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 CCL99274.1 - 6.5e-05 21.7 2.5 0.012 14.3 0.5 2.9 2 1 0 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.2 CCL99274.1 - 0.00035 19.7 0.5 0.00063 18.9 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CCL99274.1 - 0.0011 18.1 0.1 0.0024 17.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 CCL99274.1 - 0.0011 18.1 0.9 0.011 14.8 0.2 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 CCL99274.1 - 0.0024 16.8 0.4 0.074 11.9 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 CCL99274.1 - 0.0032 16.3 0.1 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CCL99274.1 - 0.0061 16.6 0.0 0.029 14.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CCL99274.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 CCL99274.1 - 1.6 8.4 4.1 13 5.4 0.6 3.0 3 1 1 4 4 4 0 FAD-NAD(P)-binding Aminotran_1_2 PF00155.16 CCL99275.1 - 1.2e-33 116.5 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCL99275.1 - 0.034 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase LRR_4 PF12799.2 CCL99276.1 - 5.6e-29 99.2 25.4 1.9e-05 24.1 1.0 9.0 4 1 8 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCL99276.1 - 8.8e-25 86.2 26.0 2.3e-06 27.2 1.7 6.6 5 1 1 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 CCL99276.1 - 4.8e-05 22.8 24.8 7.6 7.0 0.6 10.8 10 2 0 10 10 10 2 Leucine Rich Repeat LRR_7 PF13504.1 CCL99276.1 - 0.00023 20.8 29.2 8.4 7.0 0.2 11.9 12 1 0 12 12 12 1 Leucine rich repeat LRR_9 PF14580.1 CCL99276.1 - 0.53 9.8 8.2 4.8 6.6 0.6 3.7 2 1 3 5 5 5 0 Leucine-rich repeat LRR_6 PF13516.1 CCL99276.1 - 5.3 7.4 25.7 14 6.0 0.4 9.4 11 1 1 12 12 12 0 Leucine Rich repeat NSP2-B_epitope PF14757.1 CCL99277.1 - 0.00087 18.8 0.3 0.00087 18.8 0.2 2.8 3 0 0 3 3 3 1 Immunogenic region of nsp2 protein of arterivirus polyprotein F-box-like PF12937.2 CCL99279.1 - 4.3e-10 39.1 0.6 9.9e-10 37.9 0.4 1.6 1 0 0 1 1 1 1 F-box-like EHN PF06441.7 CCL99280.1 - 1e-33 115.5 0.0 2.1e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CCL99280.1 - 2.9e-08 33.8 2.0 4e-08 33.4 0.3 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL99280.1 - 2.9e-05 23.7 0.0 5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.6 CCL99283.1 - 5.5e-23 81.6 0.0 1.1e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1737 PF08410.5 CCL99283.1 - 0.062 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Pro-kuma_activ PF09286.6 CCL99284.1 - 9.3e-41 139.2 0.3 4.9e-40 136.8 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCL99284.1 - 1.7e-07 30.6 0.6 2.7e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.6 CCL99285.1 - 3e-38 131.0 0.9 8.9e-38 129.5 0.0 2.3 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Nucleoporin_FG PF13634.1 CCL99285.1 - 4.5e-11 42.9 128.4 5e-09 36.3 38.0 3.8 2 1 2 4 4 4 2 Nucleoporin FG repeat region Arrestin_C PF02752.17 CCL99286.1 - 0.066 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Mito_carr PF00153.22 CCL99287.1 - 3.2e-34 116.5 0.6 1.8e-17 62.7 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein Methyltransf_16 PF10294.4 CCL99289.1 - 4.9e-11 42.3 0.0 4.6e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase ATG22 PF11700.3 CCL99290.1 - 8.1e-120 400.5 28.2 9.7e-120 400.2 19.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Mitofilin PF09731.4 CCL99291.1 - 1.1e-112 377.6 9.8 1.3e-112 377.4 6.8 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Calci_bind_CcbP PF11535.3 CCL99291.1 - 0.51 10.6 4.2 5.1 7.4 0.4 3.2 2 1 1 3 3 3 0 Calcium binding ABC_tran PF00005.22 CCL99292.1 - 7.9e-51 171.9 0.0 9.9e-29 100.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCL99292.1 - 2.7e-42 145.0 15.3 4e-24 85.4 5.8 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.1 CCL99292.1 - 2.8e-09 36.3 2.1 5.4e-05 22.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CCL99292.1 - 6.6e-09 35.3 6.1 0.0011 18.2 1.7 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 CCL99292.1 - 1.2e-07 30.9 1.0 0.011 14.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 CCL99292.1 - 1.9e-07 30.7 0.5 0.014 14.7 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CCL99292.1 - 5.3e-06 26.5 0.3 0.062 13.2 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 CCL99292.1 - 8.9e-06 25.8 1.2 0.16 11.9 0.2 4.1 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CCL99292.1 - 1e-05 25.9 0.2 0.0017 18.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CCL99292.1 - 1.2e-05 25.2 3.0 0.003 17.3 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CCL99292.1 - 6.5e-05 22.5 0.1 0.24 10.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 CCL99292.1 - 0.00014 22.1 0.0 0.047 13.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCL99292.1 - 0.00027 21.4 0.1 0.65 10.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 CCL99292.1 - 0.00029 20.3 4.2 0.63 9.4 0.3 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_17 PF13207.1 CCL99292.1 - 0.00034 21.4 0.1 0.21 12.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CCL99292.1 - 0.00055 18.6 0.7 0.3 9.6 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 CCL99292.1 - 0.00057 19.0 0.7 0.41 9.7 0.2 2.4 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 CCL99292.1 - 0.00091 19.1 0.2 0.69 9.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCL99292.1 - 0.001 18.9 0.0 0.82 9.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 CCL99292.1 - 0.0012 19.0 2.6 2.9 8.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 CCL99292.1 - 0.003 17.2 0.5 0.16 11.6 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 CCL99292.1 - 0.0068 15.9 0.2 1.3 8.4 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 CCL99292.1 - 0.01 15.0 0.5 0.59 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CCL99292.1 - 0.011 15.6 0.0 6.5 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CCL99292.1 - 0.013 14.5 1.3 0.82 8.5 0.0 2.6 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CCL99292.1 - 0.016 14.9 0.5 0.38 10.5 0.1 2.9 2 0 0 2 2 2 0 Part of AAA domain DUF815 PF05673.8 CCL99292.1 - 0.069 12.0 1.2 7.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.7 CCL99292.1 - 0.069 12.8 3.6 3.9 7.0 0.3 2.8 3 0 0 3 3 2 0 NACHT domain RNA_helicase PF00910.17 CCL99292.1 - 0.092 12.9 1.2 7.7 6.7 0.0 2.7 3 0 0 3 3 2 0 RNA helicase Zot PF05707.7 CCL99292.1 - 0.093 12.1 0.1 0.68 9.3 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) cobW PF02492.14 CCL99292.1 - 0.098 12.0 2.5 4.1 6.8 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 CCL99292.1 - 0.13 12.4 0.4 26 4.9 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CCL99292.1 - 0.16 11.5 2.9 5 6.6 0.1 2.9 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CCL99292.1 - 0.16 11.8 0.8 10 6.0 0.1 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ResIII PF04851.10 CCL99292.1 - 0.17 11.6 0.2 9.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 CCL99292.1 - 0.19 11.2 0.2 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.10 CCL99292.1 - 0.25 9.9 0.4 7.9 5.0 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein Pox_A32 PF04665.7 CCL99292.1 - 0.51 9.5 0.9 8.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Trehalase PF01204.13 CCL99293.1 - 1.3e-155 519.0 0.0 1.6e-155 518.6 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CCL99293.1 - 3.2e-12 45.5 0.1 5.5e-12 44.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Lipase_3 PF01764.20 CCL99294.1 - 2e-08 33.9 0.0 6.2e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CCL99294.1 - 0.054 13.2 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family CBP PF12192.3 CCL99295.1 - 0.061 13.2 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Fungal calcium binding protein Asp PF00026.18 CCL99298.1 - 4.7e-39 134.4 0.2 2e-38 132.4 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Abhydrolase_5 PF12695.2 CCL99300.1 - 0.00037 20.2 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCL99300.1 - 0.00042 19.6 0.0 0.00064 19.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CCL99300.1 - 0.00078 19.3 0.0 0.0015 18.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CCL99300.1 - 0.0022 17.2 0.0 0.003 16.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 CCL99300.1 - 0.011 15.3 0.4 0.052 13.0 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ctf8 PF09696.5 CCL99301.1 - 1.1e-18 67.1 1.5 3.9e-18 65.4 1.1 1.7 1 1 0 1 1 1 1 Ctf8 PEX11 PF05648.9 CCL99302.1 - 6.1e-10 38.7 1.6 3.1e-06 26.6 0.0 2.5 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) E1-E2_ATPase PF00122.15 CCL99303.1 - 3e-57 193.3 1.1 7.3e-57 192.0 0.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCL99303.1 - 9.3e-44 149.1 6.8 9.3e-44 149.1 4.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCL99303.1 - 3.3e-28 99.5 0.0 8.5e-28 98.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCL99303.1 - 3.7e-17 62.0 0.0 7.7e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCL99303.1 - 4.9e-15 56.2 0.2 2.9e-14 53.6 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCL99303.1 - 6.7e-10 38.2 0.1 1.1e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCL99303.1 - 0.00032 20.3 0.5 0.0055 16.3 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase COQ9 PF08511.6 CCL99304.1 - 4.7e-11 42.0 0.0 9.6e-11 41.0 0.0 1.5 1 0 0 1 1 1 1 COQ9 BH3 PF15285.1 CCL99304.1 - 0.17 11.4 0.9 1.6 8.3 0.0 2.6 3 0 0 3 3 3 0 Beclin-1 BH3 domain, Bcl-2-interacting Ost4 PF10215.4 CCL99305.1 - 0.0093 15.4 0.1 0.025 14.0 0.1 1.7 1 0 0 1 1 1 1 Oligosaccaryltransferase PTPlike_phytase PF14566.1 CCL99307.1 - 4.1e-114 377.3 0.0 2e-36 125.2 0.0 3.9 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.22 CCL99307.1 - 7.1e-07 28.8 0.0 0.043 13.1 0.0 3.3 3 0 0 3 3 3 3 Protein-tyrosine phosphatase DSPc PF00782.15 CCL99307.1 - 1.3e-06 27.9 0.1 0.029 13.9 0.0 4.1 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain TFIIE-A_C-term PF11521.3 CCL99307.1 - 0.00062 19.6 0.0 1.8 8.5 0.0 3.5 3 0 0 3 3 3 2 C-terminal general transcription factor TFIIE alpha BBP1_C PF15272.1 CCL99307.1 - 0.17 11.4 2.2 14 5.1 0.0 3.0 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal eIF-6 PF01912.13 CCL99308.1 - 1.8e-85 285.0 0.3 2.7e-85 284.4 0.2 1.3 1 0 0 1 1 1 1 eIF-6 family Methyltransf_28 PF02636.12 CCL99309.1 - 2.6e-64 217.0 0.0 3.4e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Fra10Ac1 PF09725.4 CCL99310.1 - 7.3e-40 135.7 1.9 1.1e-39 135.1 1.3 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DnaJ PF00226.26 CCL99311.1 - 2e-27 94.6 2.2 2.9e-27 94.1 1.5 1.2 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCL99311.1 - 4.1e-20 71.4 0.2 2.7e-18 65.6 0.0 2.6 2 0 0 2 2 2 1 DnaJ C terminal domain RPT PF13446.1 CCL99311.1 - 0.1 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF202 PF02656.10 CCL99312.1 - 0.00048 20.3 1.0 0.00048 20.3 0.7 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF2162 PF09930.4 CCL99312.1 - 0.024 13.7 0.8 0.21 10.7 0.1 2.0 2 0 0 2 2 2 0 Predicted transporter (DUF2162) LrgB PF04172.11 CCL99312.1 - 0.078 12.1 0.4 0.12 11.5 0.3 1.3 1 0 0 1 1 1 0 LrgB-like family DUF3519 PF12033.3 CCL99313.1 - 0.044 13.9 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) DEAD PF00270.24 CCL99314.1 - 3.3e-34 117.8 0.0 2.4e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCL99314.1 - 9.5e-24 83.0 0.2 2e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCL99314.1 - 0.026 14.6 0.4 0.2 11.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.1 CCL99314.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.1 CCL99314.1 - 0.051 12.6 0.1 0.12 11.4 0.1 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit NmrA PF05368.8 CCL99317.1 - 1.6e-33 115.8 0.0 1.9e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CCL99317.1 - 2e-08 34.4 0.0 4.5e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 CCL99318.1 - 3.5e-36 124.6 0.0 4.3e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CCL99318.1 - 2e-08 34.4 0.0 3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCL99319.1 - 1.1e-34 119.6 0.0 1.3e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CCL99319.1 - 8.1e-12 45.5 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Acyl_transf_1 PF00698.16 CCL99321.1 - 1.6e-65 221.5 0.0 3.8e-63 213.7 0.0 3.1 3 0 0 3 3 3 1 Acyl transferase domain DUF647 PF04884.9 CCL99321.1 - 1.5e-41 142.2 0.2 3.9e-41 140.9 0.1 1.6 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis MaoC_dehydratas PF01575.14 CCL99321.1 - 6.6e-30 103.0 0.3 2.3e-29 101.2 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 CCL99321.1 - 1.5e-29 101.5 0.4 1.5e-29 101.5 0.3 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF1729) Pro_CA PF00484.14 CCL99321.1 - 6e-25 88.0 0.1 1.9e-22 79.9 0.0 2.6 2 0 0 2 2 2 1 Carbonic anhydrase ketoacyl-synt PF00109.21 CCL99321.1 - 2e-22 79.9 0.4 5.3e-22 78.5 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 CCL99321.1 - 1e-18 68.0 0.0 1.8e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 CCL99321.1 - 7.1e-16 58.1 0.1 1.8e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 CCL99321.1 - 1.7e-14 53.6 0.0 4.2e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.1 CCL99321.1 - 8.4e-14 51.4 0.3 4.7e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.20 CCL99321.1 - 2.1e-05 24.4 0.0 0.0021 17.9 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase F-box-like PF12937.2 CCL99322.1 - 0.0079 15.8 0.5 0.023 14.4 0.4 1.8 1 0 0 1 1 1 1 F-box-like DUF4231 PF14015.1 CCL99323.1 - 0.15 12.0 5.9 0.14 12.1 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Pectate_lyase_3 PF12708.2 CCL99324.1 - 4e-87 292.0 21.8 1.8e-66 224.5 8.8 3.0 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 CCL99324.1 - 2.9e-06 26.6 2.3 0.017 14.5 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 CCL99324.1 - 0.0015 18.3 35.6 0.0046 16.7 8.2 3.1 2 1 2 4 4 4 2 Right handed beta helix region GTP_EFTU PF00009.22 CCL99325.1 - 7.1e-40 136.4 1.2 2.9e-39 134.4 0.8 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCL99325.1 - 2.4e-24 85.3 0.1 6.1e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCL99325.1 - 4.3e-09 36.3 5.7 0.00014 21.8 0.0 4.1 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCL99325.1 - 2e-06 27.7 0.1 5e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CCL99325.1 - 1.1e-05 24.9 0.3 0.0091 15.4 0.1 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 CCL99325.1 - 0.00027 20.2 0.0 0.00064 19.0 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family ArgK PF03308.11 CCL99325.1 - 0.00029 19.7 2.5 0.0019 17.0 0.2 2.3 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 CCL99325.1 - 0.00061 20.2 0.1 0.002 18.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein IF2_N PF04760.10 CCL99325.1 - 0.0064 16.1 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.5 CCL99325.1 - 0.011 14.9 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 CCL99325.1 - 0.037 13.7 0.5 0.15 11.7 0.2 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CHORD PF04968.7 CCL99326.1 - 2.4e-50 168.6 12.1 5e-25 87.5 2.4 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 CCL99326.1 - 3.6e-14 53.0 0.0 1.3e-13 51.2 0.0 1.9 2 0 0 2 2 2 1 CS domain BTK PF00779.14 CCL99326.1 - 8.3 6.1 12.1 15 5.3 0.6 3.5 2 1 0 2 2 2 0 BTK motif Mito_carr PF00153.22 CCL99327.1 - 3e-10 39.6 0.8 0.00093 18.8 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_23 PF13489.1 CCL99327.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain 2OG-FeII_Oxy_2 PF13532.1 CCL99328.1 - 4.6e-10 39.6 0.0 4.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 CCL99330.1 - 1.7e-29 100.5 2.6 3.9e-14 51.9 0.3 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCL99330.1 - 1.5e-05 23.9 1.6 0.00046 19.0 0.2 3.0 1 1 2 4 4 4 1 Nup133 N terminal like Hira PF07569.6 CCL99330.1 - 0.00077 18.7 0.0 0.98 8.5 0.0 2.3 2 0 0 2 2 2 2 TUP1-like enhancer of split DUF3312 PF11768.3 CCL99330.1 - 0.02 13.1 0.0 0.026 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Nbas_N PF15492.1 CCL99330.1 - 0.05 12.6 0.0 20 4.1 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal OGFr_III PF04680.8 CCL99330.1 - 0.5 10.5 5.4 0.16 12.1 0.7 2.1 2 0 0 2 2 2 0 Opioid growth factor receptor repeat Glu_synthase PF01645.12 CCL99331.1 - 3.3e-158 526.4 0.1 1.1e-157 524.7 0.0 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CCL99331.1 - 8.3e-129 429.3 0.0 1.1e-128 428.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CCL99331.1 - 2.3e-118 394.6 0.0 3.5e-118 394.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 CCL99331.1 - 2.9e-70 235.3 3.2 6.4e-70 234.2 2.2 1.6 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CCL99331.1 - 9.3e-24 83.1 0.2 2.1e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CCL99331.1 - 9.1e-18 64.8 0.0 2.6e-17 63.3 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCL99331.1 - 4.4e-10 39.9 0.1 0.00099 19.2 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCL99331.1 - 1e-08 35.4 0.1 7.6e-05 23.0 0.0 4.2 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCL99331.1 - 1e-07 31.8 0.0 4.1e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCL99331.1 - 1.6e-05 23.5 0.7 4e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 CCL99331.1 - 4.4e-05 22.5 0.1 0.00065 18.7 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCL99331.1 - 0.00011 21.2 0.1 0.0036 16.2 0.0 2.8 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 CCL99331.1 - 0.0017 17.5 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 CCL99331.1 - 0.0022 18.2 0.3 0.43 10.8 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding FMN_dh PF01070.13 CCL99331.1 - 0.0032 16.3 0.6 0.021 13.6 0.5 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase FAD_binding_3 PF01494.14 CCL99331.1 - 0.0075 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CCL99331.1 - 0.0091 15.1 0.5 0.024 13.7 0.0 1.9 2 0 0 2 2 2 1 Thi4 family AdoHcyase_NAD PF00670.16 CCL99331.1 - 0.016 15.0 0.2 9.8 5.9 0.0 2.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_6 PF13522.1 CCL99331.1 - 0.043 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain AlaDh_PNT_C PF01262.16 CCL99331.1 - 0.048 13.2 0.0 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 CCL99331.1 - 0.054 12.6 0.3 1.3 8.1 0.0 2.8 3 0 0 3 3 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.14 CCL99331.1 - 0.077 11.1 0.0 3.6 5.6 0.0 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 CCL99331.1 - 0.089 12.5 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 CCL99331.1 - 0.12 11.7 0.1 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CCL99331.1 - 0.16 11.6 0.0 0.44 10.1 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 CCL99331.1 - 0.25 10.1 0.5 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 CCL99331.1 - 0.29 11.2 0.1 51 3.9 0.0 3.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Acetyltransf_13 PF13880.1 CCL99332.1 - 1.4e-12 47.1 0.0 2.8e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 CCL99332.1 - 2.5e-08 33.3 0.2 4e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 CCL99332.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family WD40 PF00400.27 CCL99333.1 - 2.1e-11 43.2 16.8 6.7e-05 22.6 0.5 5.3 7 0 0 7 7 7 3 WD domain, G-beta repeat MAAL_C PF07476.6 CCL99333.1 - 0.12 11.2 0.2 0.19 10.6 0.2 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DUF1682 PF07946.9 CCL99333.1 - 3.2 6.5 8.8 5.7 5.6 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) adh_short PF00106.20 CCL99334.1 - 3.2e-18 66.1 0.0 8e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCL99334.1 - 9.2e-06 25.4 0.0 1.9e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCL99334.1 - 0.00073 19.3 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCL99334.1 - 0.0023 17.4 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCL99334.1 - 0.004 17.1 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCL99334.1 - 0.0099 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CCL99334.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 CCL99334.1 - 0.066 12.3 0.0 0.15 11.2 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) 2OG-FeII_Oxy_3 PF13640.1 CCL99335.1 - 6.9e-08 32.9 0.0 1.3e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CCL99335.1 - 2.4e-07 30.3 0.0 4.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CCL99335.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DEAD PF00270.24 CCL99336.1 - 4.3e-46 156.5 0.0 7.4e-46 155.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_M24 PF00557.19 CCL99336.1 - 1.9e-39 135.4 1.0 2.6e-39 134.9 0.1 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Helicase_C PF00271.26 CCL99336.1 - 6.7e-26 89.9 0.0 1.4e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Creatinase_N PF01321.13 CCL99336.1 - 2.6e-05 24.7 0.0 4.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain ResIII PF04851.10 CCL99336.1 - 0.0011 18.8 0.0 0.0028 17.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit 2OG-FeII_Oxy_2 PF13532.1 CCL99337.1 - 5.2e-18 65.5 0.0 5.8e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily UBA PF00627.26 CCL99337.1 - 0.035 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain HBS1_N PF08938.5 CCL99337.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus DUF1296 PF06972.6 CCL99337.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) DUF4648 PF15505.1 CCL99337.1 - 0.2 11.8 2.3 0.52 10.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) IGPD PF00475.13 CCL99338.1 - 5.5e-41 139.8 0.1 4.1e-40 136.9 0.0 2.0 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase CDC45 PF02724.9 CCL99339.1 - 2.1e-181 604.1 0.0 2.6e-181 603.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein zf-Mss51 PF13824.1 CCL99340.1 - 2.7e-25 87.9 1.9 5e-25 87.1 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.6 CCL99340.1 - 0.32 11.1 3.2 0.75 9.9 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-MYND PF01753.13 CCL99340.1 - 1.7 8.5 6.3 3.1 7.7 4.3 1.4 1 0 0 1 1 1 0 MYND finger Scramblase PF03803.10 CCL99341.1 - 3.2e-50 170.2 0.0 1.5e-49 168.0 0.0 1.8 1 1 0 1 1 1 1 Scramblase Peptidase_M13_N PF05649.8 CCL99342.1 - 1.2e-86 291.2 0.0 1.6e-86 290.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CCL99342.1 - 7.6e-53 178.7 0.0 1.1e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 TRAPPC10 PF12584.3 CCL99343.1 - 3.7e-27 94.6 0.0 6.2e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 FliL PF03748.9 CCL99344.1 - 0.033 14.1 0.8 0.19 11.7 0.0 2.7 3 1 1 4 4 4 0 Flagellar basal body-associated protein FliL Lyase_1 PF00206.15 CCL99345.1 - 1e-92 310.6 0.2 5.5e-92 308.2 0.0 2.3 3 0 0 3 3 3 1 Lyase Far-17a_AIG1 PF04750.9 CCL99345.1 - 8.3e-36 123.0 4.1 1.3e-35 122.4 2.9 1.3 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein ASL_C2 PF14698.1 CCL99345.1 - 1.6e-28 98.5 0.0 4.4e-28 97.1 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SNARE PF05739.14 CCL99345.1 - 5.1e-14 51.7 3.4 5.1e-14 51.7 2.4 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCL99345.1 - 1.3e-12 47.8 2.0 1.3e-12 47.8 1.4 2.6 2 0 0 2 2 2 1 Syntaxin Spectrin PF00435.16 CCL99345.1 - 0.0032 17.7 1.6 0.48 10.7 0.0 2.8 2 0 0 2 2 2 1 Spectrin repeat Syntaxin_2 PF14523.1 CCL99345.1 - 0.019 15.0 11.0 0.014 15.4 3.8 2.5 2 0 0 2 2 2 0 Syntaxin-like protein VitD-bind_III PF09164.5 CCL99345.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III MCPsignal PF00015.16 CCL99345.1 - 0.23 10.9 10.8 0.022 14.3 1.7 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2116 PF09889.4 CCL99345.1 - 0.32 10.8 2.4 0.86 9.4 1.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) BLOC1_2 PF10046.4 CCL99345.1 - 0.41 10.8 3.9 1.4 9.0 0.5 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 D5_N PF08706.6 CCL99345.1 - 0.43 10.6 3.0 6.9 6.7 2.1 2.7 1 1 0 1 1 1 0 D5 N terminal like CCG PF02754.11 CCL99346.1 - 0.12 12.4 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Cysteine-rich domain Aminotran_1_2 PF00155.16 CCL99347.1 - 7.5e-64 215.9 0.0 7.8e-62 209.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Arch_ATPase PF01637.13 CCL99349.1 - 8e-16 58.4 0.0 1.9e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 CCL99349.1 - 2.3e-06 27.7 2.0 9.3e-06 25.7 0.0 2.9 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 CCL99349.1 - 0.0012 18.9 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CCL99349.1 - 0.044 13.9 0.0 6.8 6.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCL99349.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CCL99349.1 - 0.14 12.1 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Piwi PF02171.12 CCL99350.1 - 1.7e-83 280.1 0.1 2.2e-83 279.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CCL99350.1 - 1.8e-19 69.4 0.1 3.6e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CCL99350.1 - 7.5e-19 66.8 0.0 2e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Abhydrolase_6 PF12697.2 CCL99351.1 - 1.6e-24 87.0 0.0 2.6e-24 86.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL99351.1 - 2.7e-16 59.8 0.1 7.6e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL99351.1 - 1.3e-07 31.4 0.0 3e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CCL99351.1 - 2.6e-06 26.1 0.0 0.0084 14.6 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 CCL99351.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase AAA_11 PF13086.1 CCL99352.1 - 1.8e-59 201.1 0.2 1.3e-58 198.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CCL99352.1 - 2.7e-47 160.7 0.0 4.1e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCL99352.1 - 2.8e-10 40.0 0.0 4.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCL99352.1 - 1.2e-09 37.8 0.2 8.3e-09 35.0 0.0 2.5 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 CCL99352.1 - 1e-07 31.7 0.2 0.2 11.1 0.0 3.5 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CCL99352.1 - 1.1e-06 28.8 0.0 0.0097 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 CCL99352.1 - 0.00043 20.1 0.0 0.06 13.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CCL99352.1 - 0.0017 17.3 0.1 0.033 13.1 0.0 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 CCL99352.1 - 0.0027 17.7 0.3 0.012 15.5 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain PhoH PF02562.11 CCL99352.1 - 0.0031 16.7 0.0 0.3 10.2 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.24 CCL99352.1 - 0.005 17.0 0.5 0.055 13.6 0.0 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 CCL99352.1 - 0.01 15.1 0.0 0.081 12.2 0.0 2.1 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 CCL99352.1 - 0.01 14.8 0.0 0.77 8.6 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase AAA_25 PF13481.1 CCL99352.1 - 0.015 14.6 0.0 0.078 12.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain HSP20 PF00011.16 CCL99353.1 - 2.5e-14 52.9 0.0 4.9e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CSTF2_hinge PF14327.1 CCL99354.1 - 9.7e-22 76.8 2.9 9.7e-22 76.8 2.0 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 ApbA_C PF08546.6 CCL99355.1 - 5.9e-18 65.0 0.0 5.4e-15 55.4 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CCL99355.1 - 8.4e-17 61.0 0.0 2e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Abhydrolase_6 PF12697.2 CCL99356.1 - 9.3e-29 100.9 0.2 2.2e-28 99.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL99356.1 - 7.7e-18 64.8 0.2 4e-10 39.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL99356.1 - 3.9e-09 36.4 0.0 5.3e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCL99356.1 - 3.1e-05 23.7 0.1 9.4e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 CCL99356.1 - 0.17 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_6 PF12697.2 CCL99357.1 - 1.9e-30 106.4 0.0 6.2e-30 104.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL99357.1 - 5.5e-14 52.2 0.1 3.1e-12 46.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL99357.1 - 1.2e-10 41.3 0.0 2e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCL99357.1 - 6.5e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 CCL99357.1 - 0.0029 16.1 0.0 0.007 14.9 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 CCL99357.1 - 0.14 11.3 0.0 0.4 9.9 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 CCL99358.1 - 2.2e-21 76.8 0.5 3.4e-11 43.4 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL99358.1 - 6.1e-09 35.7 0.3 0.00022 20.8 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL99358.1 - 3.8e-05 23.4 0.1 0.0002 21.1 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCL99358.1 - 0.017 15.0 0.0 0.088 12.6 0.0 2.2 3 0 0 3 3 3 0 Putative lysophospholipase Peptidase_A24 PF01478.13 CCL99359.1 - 1.4 9.0 8.2 3.6 7.8 5.7 1.7 1 1 0 1 1 1 0 Type IV leader peptidase family Ribonucleas_3_3 PF14622.1 CCL99360.1 - 1e-16 61.0 0.0 1.8e-15 57.0 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CCL99360.1 - 0.062 13.7 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III domain Fungal_trans PF04082.13 CCL99361.1 - 8.9e-19 67.3 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain COG4 PF08318.7 CCL99361.1 - 0.34 9.6 3.2 0.56 8.9 2.2 1.2 1 0 0 1 1 1 0 COG4 transport protein Yae1_N PF09811.4 CCL99362.1 - 0.0043 16.5 1.1 0.0043 16.5 0.7 1.7 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Exo_endo_phos PF03372.18 CCL99363.1 - 3.1e-16 60.0 0.1 3.6e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L27e PF01777.13 CCL99364.1 - 3e-34 116.9 0.9 4.5e-34 116.4 0.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family FAD_binding_4 PF01565.18 CCL99364.1 - 1.2e-16 60.3 2.2 2.2e-16 59.5 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CCL99364.1 - 5e-07 29.5 0.2 1.2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like KOW PF00467.24 CCL99364.1 - 0.055 13.2 0.3 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 KOW motif BTB PF00651.26 CCL99365.1 - 1.3e-07 31.6 0.0 2.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CCL99366.1 - 1.2e-10 41.3 0.0 2.4e-10 40.4 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain RhoGAP PF00620.22 CCL99367.1 - 8.4e-15 54.6 0.1 2.4e-14 53.2 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.18 CCL99367.1 - 9.8e-13 48.6 0.0 1.9e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.26 CCL99367.1 - 9.9e-07 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain PapD-like PF14874.1 CCL99367.1 - 0.078 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like Pro_isomerase PF00160.16 CCL99368.1 - 2e-45 154.7 0.0 4.4e-45 153.6 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CCL99368.1 - 0.00014 21.4 3.8 0.14 11.8 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCL99368.1 - 0.21 11.5 5.4 3 7.9 0.6 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCL99368.1 - 0.32 10.6 3.1 10 5.9 0.3 3.0 2 1 2 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.2 CCL99370.1 - 0.00037 20.1 2.1 0.001 18.7 1.4 1.8 1 0 0 1 1 1 1 F-box-like PalH PF08733.5 CCL99370.1 - 3.5 6.3 15.8 0.14 10.9 6.0 2.0 2 0 0 2 2 2 0 PalH/RIM21 AMP-binding PF00501.23 CCL99371.1 - 4.4e-86 288.8 0.6 8e-86 288.0 0.1 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCL99371.1 - 1.4e-21 77.2 1.5 1.9e-21 76.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Crp PF00325.15 CCL99371.1 - 0.062 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF2461 PF09365.5 CCL99372.1 - 6.9e-47 159.5 0.4 4.3e-46 156.9 0.0 2.3 2 1 0 2 2 2 1 Conserved hypothetical protein (DUF2461) CDC27 PF09507.5 CCL99372.1 - 0.31 10.2 23.3 0.43 9.7 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peroxin-3 PF04882.7 CCL99374.1 - 5.8e-101 338.3 0.0 6.9e-101 338.0 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 GFO_IDH_MocA PF01408.17 CCL99375.1 - 7.5e-15 55.5 0.0 1.4e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCL99375.1 - 2.1e-06 27.5 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_1 PF00232.13 CCL99376.1 - 1.7e-132 441.8 0.0 2.2e-132 441.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 CCL99376.1 - 0.016 14.6 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core Zn_clus PF00172.13 CCL99377.1 - 1.6e-05 24.7 9.2 2.8e-05 23.9 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 CCL99377.1 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold PI-PLC-X PF00388.14 CCL99378.1 - 3.9e-54 182.0 0.0 8.1e-54 180.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CCL99378.1 - 4.9e-39 132.9 0.0 9.3e-39 132.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CCL99378.1 - 7.1e-08 32.3 0.8 0.00083 19.3 0.0 3.5 2 1 1 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 CCL99378.1 - 4.4e-07 29.6 0.0 1.5e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_7 PF13499.1 CCL99378.1 - 1.6e-06 28.1 3.0 0.00081 19.4 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCL99378.1 - 0.017 14.4 0.1 0.35 10.2 0.0 2.8 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 CCL99378.1 - 0.11 12.4 0.5 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain Seryl_tRNA_N PF02403.17 CCL99379.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Sdh_cyt PF01127.17 CCL99380.1 - 1.9e-24 85.7 1.5 2.4e-24 85.4 1.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PIF1 PF05970.9 CCL99381.1 - 4.7e-51 173.8 1.5 3.8e-43 147.8 0.1 2.7 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CCL99381.1 - 1.9e-18 66.7 0.0 4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCL99381.1 - 2.1e-08 34.3 0.0 5.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCL99381.1 - 1.7e-07 31.4 0.2 3e-05 24.0 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Herpes_Helicase PF02689.9 CCL99381.1 - 1.1e-05 23.4 0.1 0.00081 17.2 0.0 2.2 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.1 CCL99381.1 - 1.7e-05 24.4 0.1 5.9e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 CCL99381.1 - 7.6e-05 22.0 0.1 0.00016 20.9 0.1 1.6 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.13 CCL99381.1 - 0.0001 21.9 0.3 0.038 13.5 0.1 3.0 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CCL99381.1 - 0.00012 21.7 0.2 0.44 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 CCL99381.1 - 0.0005 19.0 0.1 0.0011 17.9 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.1 CCL99381.1 - 0.00061 19.9 0.1 0.002 18.2 0.0 1.9 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.16 CCL99381.1 - 0.0011 18.1 0.1 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CCL99381.1 - 0.0011 18.3 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 CCL99381.1 - 0.0017 18.0 0.5 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 CCL99381.1 - 0.002 18.2 0.1 0.0053 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CCL99381.1 - 0.0041 17.4 0.2 0.016 15.5 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 CCL99381.1 - 0.0051 16.5 0.1 0.016 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CCL99381.1 - 0.0094 14.9 0.1 0.018 14.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 CCL99381.1 - 0.01 14.8 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 CCL99381.1 - 0.013 14.6 0.1 0.043 12.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 CCL99381.1 - 0.014 14.8 0.1 0.032 13.7 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ArgK PF03308.11 CCL99381.1 - 0.016 13.9 0.1 0.027 13.2 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_14 PF13173.1 CCL99381.1 - 0.025 14.4 0.0 0.12 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCL99381.1 - 0.028 13.8 0.0 0.076 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 CCL99381.1 - 0.033 12.8 0.1 0.054 12.1 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AFG1_ATPase PF03969.11 CCL99381.1 - 0.064 12.0 0.1 0.15 10.8 0.1 1.6 1 1 0 1 1 1 0 AFG1-like ATPase RNA_helicase PF00910.17 CCL99381.1 - 0.07 13.3 0.1 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Helicase_RecD PF05127.9 CCL99381.1 - 0.072 12.7 0.3 0.22 11.1 0.2 1.8 1 1 0 1 1 1 0 Helicase FtsK_SpoIIIE PF01580.13 CCL99381.1 - 0.087 12.2 0.1 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 CCL99381.1 - 0.14 11.8 0.2 0.61 9.7 0.1 1.9 1 1 0 1 1 1 0 Archaeal ATPase UvrD-helicase PF00580.16 CCL99381.1 - 0.22 10.7 0.8 0.35 10.1 0.6 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvdE PF03851.9 CCL99383.1 - 5e-89 297.9 0.0 9.9e-89 297.0 0.0 1.5 1 0 0 1 1 1 1 UV-endonuclease UvdE Thaumatin PF00314.12 CCL99385.1 - 5.5e-59 199.1 11.0 6.5e-59 198.9 7.6 1.1 1 0 0 1 1 1 1 Thaumatin family Thaumatin PF00314.12 CCL99386.1 - 2.3e-59 200.4 10.6 2.7e-59 200.2 7.3 1.0 1 0 0 1 1 1 1 Thaumatin family WD40 PF00400.27 CCL99389.1 - 2.7e-33 112.6 11.2 2.2e-11 43.1 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Sof1 PF04158.9 CCL99389.1 - 1.3e-26 92.3 10.2 2.5e-26 91.5 7.0 1.4 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 CCL99389.1 - 0.013 15.2 0.0 0.059 13.0 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A CRC_subunit PF08624.5 CCL99390.1 - 5.3e-41 139.7 0.1 8.4e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Sds3 PF08598.6 CCL99391.1 - 2.7e-23 82.6 0.0 1.5e-22 80.1 0.0 2.2 2 0 0 2 2 2 1 Sds3-like F-box-like PF12937.2 CCL99392.1 - 0.0038 16.9 0.0 0.024 14.3 0.0 2.5 2 0 0 2 2 2 1 F-box-like GST_N_3 PF13417.1 CCL99397.1 - 7.5e-19 67.7 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCL99397.1 - 6.8e-14 51.6 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCL99397.1 - 2.1e-05 24.2 0.0 5.5e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hist_deacetyl PF00850.14 CCL99398.1 - 1.4e-47 162.4 0.0 7.5e-40 137.1 0.0 2.0 1 1 1 2 2 2 2 Histone deacetylase domain Amidase PF01425.16 CCL99399.1 - 1.6e-87 294.1 0.0 1.9e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Transp_cyt_pur PF02133.10 CCL99400.1 - 1.6e-15 56.6 14.5 2.1e-15 56.2 10.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sedlin_N PF04628.8 CCL99401.1 - 2e-25 89.1 0.0 2.2e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Cyt-b5 PF00173.23 CCL99402.1 - 1.2e-22 79.4 0.0 1.8e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OmpH PF03938.9 CCL99404.1 - 0.068 13.1 7.0 0.11 12.3 4.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 CCL99404.1 - 0.25 10.4 6.1 0.42 9.7 4.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1682 PF07946.9 CCL99404.1 - 0.88 8.3 10.3 1.4 7.7 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FlxA PF14282.1 CCL99404.1 - 1.7 8.6 16.7 1.7 8.6 7.7 2.5 2 0 0 2 2 2 0 FlxA-like protein HIG_1_N PF04588.8 CCL99405.1 - 0.0003 20.4 2.9 0.00099 18.7 2.0 1.9 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Ofd1_CTDD PF10637.4 CCL99406.1 - 1.4e-82 276.7 0.0 3.5e-79 265.6 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CCL99406.1 - 1.2e-13 51.4 0.1 8.5e-13 48.6 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BAF1_ABF1 PF04684.8 CCL99406.1 - 1.7 7.4 4.9 2.6 6.8 3.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RRM_6 PF14259.1 CCL99407.1 - 9.6e-21 73.5 0.0 7.9e-11 41.7 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCL99407.1 - 2.1e-19 68.8 0.0 4.8e-09 35.7 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL99407.1 - 1.7e-07 30.9 0.0 0.0057 16.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCL99407.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AAA PF00004.24 CCL99408.1 - 1.1e-20 74.1 0.0 2.3e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CCL99408.1 - 0.0012 18.5 0.0 0.0035 17.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CCL99408.1 - 0.01 15.8 0.2 0.89 9.5 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 CCL99408.1 - 0.012 15.7 0.1 0.59 10.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 CCL99408.1 - 0.032 13.6 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF3393 PF11873.3 CCL99408.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) IstB_IS21 PF01695.12 CCL99408.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein HIG_1_N PF04588.8 CCL99409.1 - 7.3e-06 25.6 4.8 1.4e-05 24.7 3.3 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4233 PF14017.1 CCL99409.1 - 2 8.3 6.1 7.3 6.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) UQ_con PF00179.21 CCL99410.1 - 2.9e-14 52.6 0.1 4.3e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCL99410.1 - 0.0073 16.1 0.3 0.0093 15.8 0.2 1.4 1 1 0 1 1 1 1 RWD domain His_Phos_2 PF00328.17 CCL99411.1 - 2.5e-82 277.0 0.0 1.3e-81 274.6 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CCL99411.1 - 9.6e-06 25.2 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain E1-E2_ATPase PF00122.15 CCL99412.1 - 1.3e-45 155.2 0.6 2.7e-45 154.1 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCL99412.1 - 5e-41 141.4 0.5 1.2e-40 140.1 0.4 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CCL99412.1 - 5.5e-34 116.1 7.6 6.8e-13 48.5 0.0 5.0 4 1 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 CCL99412.1 - 1.1e-19 71.4 0.0 4.4e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MafB19-deam PF14437.1 CCL99412.1 - 0.00012 21.6 1.0 0.29 10.7 0.1 3.5 3 0 0 3 3 3 1 MafB19-like deaminase Hydrolase_3 PF08282.7 CCL99412.1 - 0.0018 17.8 0.3 0.0054 16.3 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Spc97_Spc98 PF04130.8 CCL99413.1 - 1.8e-115 386.3 0.0 2.6e-115 385.8 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family RasGAP_C PF03836.10 CCL99414.1 - 4.1e-38 130.2 1.9 1.1e-37 128.8 1.3 1.8 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 CCL99414.1 - 1.9e-35 122.2 0.5 1.1e-34 119.8 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 CCL99414.1 - 2e-14 51.7 66.4 0.0018 17.7 0.2 14.3 14 0 0 14 14 14 11 IQ calmodulin-binding motif CH PF00307.26 CCL99414.1 - 1.5e-07 31.4 0.0 3.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain Glyco_hydro_43 PF04616.9 CCL99415.1 - 1.9e-10 40.3 0.8 3e-10 39.6 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Peroxidase_2 PF01328.12 CCL99416.1 - 4.8e-25 87.8 0.1 1e-24 86.7 0.0 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 Zein PF01559.11 CCL99416.1 - 0.024 13.8 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Zein seed storage protein FF PF01846.14 CCL99417.1 - 2.2e-37 126.7 16.4 2.3e-10 40.2 0.0 5.9 6 0 0 6 6 6 5 FF domain WW PF00397.21 CCL99417.1 - 3.7e-11 42.6 19.5 1.4e-09 37.6 2.1 3.0 3 0 0 3 3 3 2 WW domain HSP90 PF00183.13 CCL99418.1 - 1.2e-123 413.4 4.2 1.5e-123 413.0 2.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CCL99418.1 - 1.3e-09 37.7 0.2 3.9e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCL99418.1 - 5.6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_4 PF13418.1 CCL99420.1 - 4.5e-14 51.9 13.1 0.0086 15.8 0.3 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CCL99420.1 - 5.9e-14 51.7 15.2 0.002 18.2 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CCL99420.1 - 5.7e-07 29.3 6.0 0.57 10.2 0.2 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CCL99420.1 - 0.0016 17.9 10.1 0.17 11.4 0.4 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CCL99420.1 - 0.0025 17.9 10.4 1.5 9.1 0.1 5.4 6 0 0 6 6 6 2 Kelch motif DUF4131 PF13567.1 CCL99420.1 - 0.35 10.2 8.1 14 5.0 4.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zf-C2H2 PF00096.21 CCL99421.1 - 1.4e-07 31.4 14.2 2.6e-06 27.4 2.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCL99421.1 - 4.8e-05 23.4 1.4 4.8e-05 23.4 1.0 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCL99421.1 - 0.0011 19.1 1.9 0.0011 19.1 1.3 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-TRAF PF02176.13 CCL99421.1 - 0.027 14.8 2.7 0.058 13.7 1.9 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf-BED PF02892.10 CCL99421.1 - 0.032 14.0 1.8 0.09 12.5 1.3 1.8 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_jaz PF12171.3 CCL99421.1 - 0.037 14.1 0.7 0.037 14.1 0.5 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCL99421.1 - 0.042 14.0 1.2 0.11 12.6 0.8 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF2180 PF09947.4 CCL99421.1 - 0.078 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_2 PF12756.2 CCL99421.1 - 4.6 7.4 8.8 9.3 6.4 0.6 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Cid2 PF09774.4 CCL99422.1 - 6.5e-21 75.0 2.0 9.7e-21 74.4 1.4 1.3 1 0 0 1 1 1 1 Caffeine-induced death protein 2 MCM2_N PF12619.3 CCL99422.1 - 0.037 14.0 1.3 0.037 14.0 0.9 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 GILT PF03227.11 CCL99423.1 - 4.2e-09 36.2 0.2 4.2e-09 36.2 0.2 1.6 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Prok-E2_A PF14457.1 CCL99423.1 - 0.016 14.6 0.0 0.075 12.4 0.0 1.8 1 1 1 2 2 2 0 Prokaryotic E2 family A Yos1 PF08571.5 CCL99424.1 - 5.9e-21 74.3 0.0 7.9e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 Yos1-like VirE3 PF06661.6 CCL99424.1 - 0.087 11.9 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 VirE3 Ribosomal_L22 PF00237.14 CCL99425.1 - 8.1e-21 73.9 0.3 1.3e-20 73.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribophorin_I PF04597.9 CCL99426.1 - 3.7e-118 394.7 0.0 4.2e-118 394.6 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I BRCT PF00533.21 CCL99427.1 - 4.4e-07 29.9 0.0 8.9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Vps52 PF04129.7 CCL99428.1 - 1.4e-64 218.5 3.7 6e-45 153.7 0.2 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 CCL99428.1 - 3.8e-08 31.9 0.1 0.00013 20.2 0.2 2.2 1 1 1 2 2 2 2 Exocyst complex component Sec3 SlyX PF04102.7 CCL99428.1 - 0.036 14.4 1.4 1 9.7 0.2 3.2 3 0 0 3 3 3 0 SlyX COG2 PF06148.6 CCL99428.1 - 0.11 12.3 2.5 0.13 12.1 0.4 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cep57_MT_bd PF06657.8 CCL99428.1 - 0.15 12.0 3.6 0.25 11.3 0.7 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Phage_glycop_gL PF11108.3 CCL99428.1 - 0.2 11.6 1.6 30 4.6 0.0 3.1 3 0 0 3 3 3 0 Viral glycoprotein L MitMem_reg PF13012.1 CCL99430.1 - 3.1e-28 98.1 2.2 3.1e-28 98.1 1.5 2.2 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CCL99430.1 - 1.5e-16 60.1 0.2 3e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ribosomal_S18 PF01084.15 CCL99432.1 - 7.1e-13 48.2 0.4 1.6e-12 47.0 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 PIGA PF08288.7 CCL99432.1 - 0.15 12.4 0.1 0.44 10.9 0.0 1.7 2 0 0 2 2 2 0 PIGA (GPI anchor biosynthesis) Pkinase PF00069.20 CCL99433.1 - 1.1e-62 211.5 0.0 1.9e-41 141.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99433.1 - 5.9e-28 97.6 0.0 3.7e-23 81.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 CCL99433.1 - 2.8e-14 53.0 0.0 5.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 CCL99433.1 - 7.6e-08 31.6 0.1 0.00032 19.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCL99433.1 - 0.00048 19.9 0.1 0.0034 17.1 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCL99433.1 - 0.0065 15.5 0.3 0.035 13.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 CCL99433.1 - 0.032 14.6 0.1 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 PAS domain RIO1 PF01163.17 CCL99433.1 - 0.041 13.2 0.0 0.092 12.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 CCL99433.1 - 0.055 12.2 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UIM PF02809.15 CCL99434.1 - 0.0013 18.1 4.9 0.0013 18.1 3.4 2.6 2 0 0 2 2 2 1 Ubiquitin interaction motif Suc_Fer-like PF06999.7 CCL99435.1 - 4.4e-34 118.5 0.0 1.4e-33 116.8 0.0 1.9 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Pkinase PF00069.20 CCL99436.1 - 2.5e-67 226.7 0.0 3.2e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99436.1 - 4.5e-29 101.3 0.0 6.1e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCL99436.1 - 8.9e-15 54.9 0.1 8.9e-15 54.9 0.1 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCL99436.1 - 1.2e-07 30.9 0.0 2.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 CCL99436.1 - 1.1e-06 28.4 0.0 0.018 14.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain DUF1935 PF09149.5 CCL99436.1 - 0.04 13.9 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1935) Tim17 PF02466.14 CCL99436.1 - 0.08 12.9 0.3 0.24 11.4 0.2 1.7 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Kdo PF06293.9 CCL99436.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fork_head PF00250.13 CCL99437.1 - 1.1e-29 102.2 0.0 2e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Med18 PF09637.5 CCL99438.1 - 7.9e-08 32.1 0.0 4.8e-05 23.0 0.0 2.0 1 1 1 2 2 2 2 Med18 protein CIAPIN1 PF05093.8 CCL99440.1 - 7.6e-30 102.9 4.3 1.3e-29 102.2 3.0 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3716 PF12511.3 CCL99440.1 - 6.2 6.5 8.9 1.4 8.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) FAD_binding_6 PF00970.19 CCL99441.1 - 3.8e-10 39.7 0.0 6.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCL99441.1 - 1.2e-09 38.6 0.0 1.7e-08 34.9 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCL99441.1 - 1.6e-05 24.8 0.0 4.8e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CCL99441.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain zf-H2C2_2 PF13465.1 CCL99442.1 - 2.6e-06 27.4 13.4 0.0042 17.3 0.6 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCL99442.1 - 4.4e-06 26.6 14.5 0.0075 16.5 0.1 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCL99442.1 - 0.00024 21.2 0.1 0.00024 21.2 0.1 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 CCL99442.1 - 0.0078 16.3 3.1 0.024 14.7 1.6 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Patched PF02460.13 CCL99443.1 - 3e-70 237.1 11.6 1.9e-39 135.2 0.1 3.2 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 CCL99443.1 - 5.1e-46 155.9 17.1 2.9e-25 88.4 0.1 3.8 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 CCL99443.1 - 1.7e-05 22.4 6.6 3.9e-05 21.3 4.2 1.7 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Folate_rec PF03024.9 CCL99443.1 - 0.00015 21.4 1.7 0.00029 20.5 1.2 1.3 1 0 0 1 1 1 1 Folate receptor family zf-Paramyx-P PF13008.2 CCL99443.1 - 0.34 10.1 12.5 1.9 7.7 1.6 2.8 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein DUF1772 PF08592.6 CCL99443.1 - 2.7 7.7 12.6 0.11 12.1 1.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) MMPL PF03176.10 CCL99443.1 - 3.9 6.1 27.4 0.09 11.4 1.6 3.8 5 0 0 5 5 5 0 MMPL family RRM_1 PF00076.17 CCL99444.1 - 4.4e-13 48.6 0.0 6.6e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL99444.1 - 3.8e-07 29.8 0.0 6.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL99444.1 - 2.1e-06 27.5 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Diphthamide_syn PF01866.12 CCL99445.1 - 7.3e-87 291.4 0.0 4.5e-32 111.5 0.2 4.0 2 1 0 3 3 3 3 Putative diphthamide synthesis protein DUF3402 PF11882.3 CCL99446.1 - 6.4e-93 312.0 0.3 1.1e-87 294.7 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 CCL99446.1 - 3e-50 170.7 0.0 4.9e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Cyclin PF08613.6 CCL99447.1 - 1.1e-07 32.3 0.0 2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin ThiF PF00899.16 CCL99448.1 - 1.1e-50 170.9 0.1 1.1e-26 93.3 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 CCL99448.1 - 2.4e-46 156.9 0.1 6.6e-46 155.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CCL99448.1 - 2.1e-41 139.3 4.9 3.5e-27 93.7 0.4 3.2 4 0 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCL99448.1 - 4.6e-22 77.1 0.9 7.8e-18 63.5 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site ATP_bind_4 PF01902.12 CCL99449.1 - 3.4e-40 137.7 0.0 2.3e-31 108.8 0.0 2.4 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 CCL99449.1 - 1.1e-19 70.3 0.0 6.2e-09 35.6 0.0 3.3 3 1 1 4 4 4 2 Endoribonuclease L-PSP MFS_2 PF13347.1 CCL99450.1 - 3.8e-12 45.3 13.2 6.1e-06 24.8 0.6 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1 PF07690.11 CCL99450.1 - 5.1e-08 32.0 21.6 0.00014 20.7 4.0 3.3 2 2 0 2 2 2 2 Major Facilitator Superfamily zf-LITAF-like PF10601.4 CCL99450.1 - 0.038 13.8 2.6 0.068 13.0 0.0 2.8 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain EF-1_beta_acid PF10587.4 CCL99450.1 - 0.14 12.3 0.8 0.49 10.5 0.6 2.0 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Reticulon PF02453.12 CCL99450.1 - 0.36 10.4 0.0 0.36 10.4 0.0 3.0 3 0 0 3 3 3 0 Reticulon Ank_4 PF13637.1 CCL99451.1 - 5.1e-28 96.9 1.7 8.5e-14 51.6 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCL99451.1 - 5.2e-25 87.5 0.0 3.3e-17 62.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCL99451.1 - 1.9e-23 81.0 0.1 4.1e-09 35.8 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CCL99451.1 - 6e-17 61.2 0.7 4.1e-09 36.3 0.2 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCL99451.1 - 1e-16 59.3 0.1 3e-05 23.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat TMF_DNA_bd PF12329.3 CCL99453.1 - 0.013 15.2 2.7 0.34 10.7 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Nnf1 PF03980.9 CCL99453.1 - 0.06 13.3 0.5 2.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Nnf1 PRA-PH PF01503.12 CCL99453.1 - 0.088 13.0 0.4 0.76 10.0 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase TMF_TATA_bd PF12325.3 CCL99453.1 - 0.13 12.0 3.0 2.5 7.8 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding MOZART2 PF12926.2 CCL99453.1 - 0.16 11.5 0.5 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated CASP_C PF08172.7 CCL99453.1 - 0.28 10.1 4.4 1.2 8.1 0.2 2.2 2 1 0 2 2 2 0 CASP C terminal SlyX PF04102.7 CCL99453.1 - 0.33 11.3 2.4 1.3 9.4 0.1 2.4 2 1 0 2 2 2 0 SlyX bZIP_1 PF00170.16 CCL99453.1 - 0.63 10.0 3.1 0.8 9.7 0.5 2.2 2 1 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 CCL99453.1 - 9.3 6.1 6.5 21 5.0 0.2 2.5 3 0 0 3 3 3 0 Basic region leucine zipper Glyco_hydro_20 PF00728.17 CCL99454.1 - 7.3e-33 114.1 0.2 8.3e-33 113.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain REJ PF02010.10 CCL99454.1 - 0.028 12.7 0.2 0.031 12.5 0.2 1.1 1 0 0 1 1 1 0 REJ domain TrkH PF02386.11 CCL99455.1 - 2.8e-82 276.1 3.5 4.1e-82 275.6 2.4 1.3 1 0 0 1 1 1 1 Cation transport protein WD40 PF00400.27 CCL99455.1 - 3.9e-06 26.5 2.2 0.24 11.3 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Vps54 PF07928.7 CCL99455.1 - 0.015 15.4 0.2 0.042 13.9 0.1 1.7 1 0 0 1 1 1 0 Vps54-like protein PaaB PF06243.6 CCL99456.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Phenylacetic acid degradation B MIF4G PF02854.14 CCL99457.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain Prenyltrans_2 PF13249.1 CCL99458.1 - 4.7e-27 94.6 0.6 2.7e-12 47.0 0.0 3.6 1 1 3 4 4 4 3 Prenyltransferase-like Prenyltrans PF00432.16 CCL99458.1 - 6.7e-27 92.7 9.7 1e-08 34.5 0.4 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CCL99458.1 - 6.6e-08 32.5 0.0 0.057 13.4 0.0 3.3 3 0 0 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 CCL99458.1 - 0.077 12.2 0.0 0.59 9.3 0.0 2.3 2 0 0 2 2 2 0 A-macroglobulin complement component DUF676 PF05057.9 CCL99459.1 - 0.00017 20.9 0.0 0.00029 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CCL99459.1 - 0.00029 20.5 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CCL99459.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family FMO-like PF00743.14 CCL99460.1 - 9.9e-33 113.1 0.0 9.7e-22 76.8 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCL99460.1 - 1.7e-13 51.0 0.0 3.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCL99460.1 - 4.6e-07 29.9 0.0 7.9e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCL99460.1 - 3.5e-06 26.1 0.1 7.2e-05 21.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCL99460.1 - 0.0015 18.4 1.4 0.0057 16.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCL99460.1 - 0.0016 18.2 3.6 0.019 14.7 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 CCL99460.1 - 0.01 14.9 0.2 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DUF202 PF02656.10 CCL99461.1 - 2.4e-21 75.7 1.4 2.4e-21 75.7 1.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1625 PF07787.7 CCL99461.1 - 0.014 14.6 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) 7TM_GPCR_Srw PF10324.4 CCL99461.1 - 0.14 11.2 0.1 0.14 11.2 0.1 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF2975 PF11188.3 CCL99461.1 - 0.19 11.4 9.8 0.76 9.4 6.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF3040 PF11239.3 CCL99461.1 - 8.6 6.4 7.1 57 3.8 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) ETF PF01012.16 CCL99462.1 - 1.1e-37 129.2 0.3 1.5e-37 128.8 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Peptidase_M16 PF00675.15 CCL99463.1 - 1.9e-54 183.4 0.6 9.7e-54 181.1 0.3 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCL99463.1 - 9.2e-44 149.3 0.0 2.7e-42 144.5 0.0 2.6 3 0 0 3 3 3 1 Peptidase M16 inactive domain adh_short PF00106.20 CCL99464.1 - 1.9e-28 99.5 0.0 3e-28 98.8 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCL99464.1 - 1.7e-09 37.6 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCL99464.1 - 9.2e-09 35.4 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCL99464.1 - 8.9e-05 22.0 0.0 0.00019 20.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CCL99464.1 - 0.0043 16.8 1.8 0.015 15.0 1.1 1.9 1 1 1 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 CCL99464.1 - 0.0045 16.1 0.0 0.008 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 CCL99464.1 - 0.049 13.6 0.0 0.096 12.6 0.0 1.4 2 0 0 2 2 2 0 NADH(P)-binding Abhydrolase_5 PF12695.2 CCL99465.1 - 5.5e-14 52.1 0.1 1.1e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCL99465.1 - 5.3e-12 46.1 4.3 1.1e-11 45.0 2.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCL99465.1 - 4.2e-08 33.0 0.0 5.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 CCL99465.1 - 7.7e-06 25.6 0.8 0.0034 16.9 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCL99465.1 - 0.00037 19.7 0.0 0.00084 18.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.15 CCL99465.1 - 0.018 15.3 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Lipase PF00151.14 CCL99465.1 - 0.064 12.4 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipase FSH1 PF03959.8 CCL99465.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) HCO3_cotransp PF00955.16 CCL99466.1 - 1.6e-57 195.3 8.0 4.7e-30 104.7 1.5 3.1 2 1 1 3 3 3 3 HCO3- transporter family Inhibitor_I53 PF11714.3 CCL99466.1 - 0.2 11.6 0.0 0.53 10.3 0.0 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin His_Phos_2 PF00328.17 CCL99467.1 - 1.4e-06 27.8 0.5 0.00011 21.6 0.4 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HIG_1_N PF04588.8 CCL99467.1 - 0.009 15.7 2.2 0.053 13.2 0.1 2.4 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF1762 PF08574.5 CCL99468.1 - 1.1e-12 48.1 10.5 2.6e-12 46.9 7.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1762) NYN PF01936.13 CCL99468.1 - 0.00011 22.5 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 NYN domain SpoVIF PF14069.1 CCL99468.1 - 0.038 13.7 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Stage VI sporulation protein F Tyrosinase PF00264.15 CCL99469.1 - 2.7e-45 155.2 3.3 4.9e-45 154.4 2.3 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase PHY PF00360.15 CCL99470.1 - 1.8e-23 82.6 0.0 3.3e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 CCL99470.1 - 2.4e-22 78.7 0.0 4.6e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCL99470.1 - 4.9e-18 65.1 0.0 1.4e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 CCL99470.1 - 3e-14 53.3 0.3 1.5e-13 51.1 0.1 2.4 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 CCL99470.1 - 1.2e-12 47.6 1.3 3.3e-12 46.1 0.9 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 CCL99470.1 - 1.7e-09 38.0 0.0 7e-09 36.1 0.0 2.1 1 0 0 1 1 1 1 PAS fold OKR_DC_1_N PF03709.10 CCL99470.1 - 0.0016 18.4 0.0 0.004 17.2 0.0 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain MFS_1 PF07690.11 CCL99471.1 - 1.5e-51 175.1 11.0 2e-51 174.7 7.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 CCL99471.1 - 0.0003 18.9 10.1 0.055 11.5 2.0 4.7 2 1 4 6 6 6 4 Organic Anion Transporter Polypeptide (OATP) family DUF2207 PF09972.4 CCL99471.1 - 0.64 8.5 2.1 1.7 7.1 1.4 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) 2-oxoacid_dh PF00198.18 CCL99472.1 - 2.3e-78 262.6 0.0 3.1e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCL99472.1 - 7.7e-16 57.5 0.0 1.6e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CCL99472.1 - 0.00033 20.2 0.8 0.01 15.4 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_2 PF12700.2 CCL99472.1 - 0.002 17.3 0.2 0.051 12.7 0.1 2.2 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 CCL99472.1 - 0.004 17.4 0.1 0.33 11.3 0.1 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 CCL99472.1 - 0.009 15.6 1.4 0.011 15.4 0.1 1.7 2 0 0 2 2 2 1 Glycine cleavage H-protein MFS_1 PF07690.11 CCL99473.1 - 3.4e-42 144.4 17.2 9.1e-23 80.5 5.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCL99473.1 - 2.1e-06 26.5 11.4 2.1e-06 26.5 7.9 3.8 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 CCL99473.1 - 0.00068 18.1 5.2 0.00068 18.1 3.6 3.1 2 2 0 3 3 3 1 MFS/sugar transport protein DUF4131 PF13567.1 CCL99473.1 - 0.85 8.9 15.7 0.98 8.8 0.0 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF4131) Velvet PF11754.3 CCL99474.1 - 5.7e-29 101.1 0.0 1.7e-28 99.6 0.0 1.7 1 1 0 1 1 1 1 Velvet factor Fungal_trans PF04082.13 CCL99476.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ribosomal_L23 PF00276.15 CCL99478.1 - 9e-20 70.4 2.0 1.8e-19 69.4 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CCL99478.1 - 2.8e-19 68.9 13.2 2.8e-19 68.9 9.1 2.4 2 2 0 2 2 2 1 Ribosomal protein L23, N-terminal domain ABC_membrane PF00664.18 CCL99480.1 - 2.5e-10 40.2 0.1 2.5e-10 40.2 0.0 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region PALP PF00291.20 CCL99481.1 - 1.7e-06 27.4 0.0 2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ATPgrasp_YheCD PF14398.1 CCL99481.1 - 0.056 12.2 0.0 0.063 12.0 0.0 1.1 1 0 0 1 1 1 0 YheC/D like ATP-grasp adh_short PF00106.20 CCL99482.1 - 6.2e-14 52.2 3.2 6e-13 49.0 0.3 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCL99482.1 - 4.8e-09 36.3 0.0 0.00057 19.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCL99482.1 - 5.1e-06 26.6 0.3 1.3e-05 25.2 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCL99482.1 - 2.6e-05 23.7 0.2 3.6e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CCL99482.1 - 0.039 13.6 1.9 0.079 12.6 0.2 2.2 2 1 0 2 2 2 0 KR domain Eno-Rase_NADH_b PF12242.3 CCL99482.1 - 0.11 12.3 0.1 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4492 PF14899.1 CCL99483.1 - 0.024 14.1 3.6 2.2 7.8 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4492) DUF2730 PF10805.3 CCL99483.1 - 0.26 11.0 3.0 5 6.9 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Mem_trans PF03547.13 CCL99484.1 - 9.7e-35 119.5 1.2 1.5e-34 118.9 0.8 1.2 1 0 0 1 1 1 1 Membrane transport protein DAHP_synth_2 PF01474.11 CCL99486.1 - 2.8e-123 411.5 0.0 3.8e-123 411.1 0.0 1.1 1 0 0 1 1 1 1 Class-II DAHP synthetase family adh_short PF00106.20 CCL99486.1 - 4.4e-19 68.9 0.1 7.2e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCL99486.1 - 1.3e-08 34.7 0.1 2.1e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCL99486.1 - 0.00043 20.1 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCL99486.1 - 0.002 18.1 0.1 0.0035 17.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCL99486.1 - 0.0021 17.5 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CCL99486.1 - 0.017 14.0 0.1 0.033 13.0 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein SUI1 PF01253.17 CCL99487.1 - 5.6e-20 70.9 0.8 1.4e-19 69.7 0.6 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 CCL99487.1 - 0.03 14.2 0.2 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV EST1 PF10374.4 CCL99487.1 - 0.13 12.2 0.1 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 FAD_binding_3 PF01494.14 CCL99488.1 - 6.3e-64 216.2 0.0 7.8e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_6 PF12697.2 CCL99489.1 - 2.2e-20 73.5 0.1 2.8e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCL99489.1 - 3.9e-11 42.9 0.0 1.2e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCL99489.1 - 2.5e-05 24.0 0.0 5.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CCL99489.1 - 0.00068 19.2 0.0 0.0053 16.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_11 PF08241.7 CCL99490.1 - 1.6e-07 31.7 0.0 2.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCL99490.1 - 9.3e-07 28.7 0.0 2.1e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCL99490.1 - 5.8e-06 26.5 0.0 9.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCL99490.1 - 9.1e-06 25.3 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCL99490.1 - 3.3e-05 23.1 0.0 0.00014 21.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CCL99490.1 - 5.4e-05 23.6 0.0 8.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCL99490.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CCL99490.1 - 0.055 14.0 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 CCL99490.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NAD_binding_4 PF07993.7 CCL99492.1 - 4.2e-33 114.3 0.0 6.3e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 CCL99492.1 - 1.1e-25 89.9 0.0 3.4e-23 81.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 CCL99492.1 - 1.9e-10 40.5 0.0 4.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CCL99492.1 - 2.3e-07 30.9 0.0 5.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 CCL99493.1 - 4.3e-28 97.8 0.1 1.1e-26 93.2 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCL99493.1 - 4.6e-16 58.4 0.0 7.5e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CCL99493.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Phosphopantetheine attachment site Glyco_hydro_28 PF00295.12 CCL99494.1 - 1.1e-51 175.6 18.2 1.2e-51 175.6 10.9 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 CCL99494.1 - 1.9e-07 30.9 36.5 0.0002 21.1 23.1 3.1 1 1 1 2 2 2 2 Right handed beta helix region AcetylCoA_hyd_C PF13336.1 CCL99494.1 - 2.4 7.8 6.9 0.83 9.3 2.4 1.9 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_28 PF00295.12 CCL99495.1 - 2e-55 188.0 19.6 2.5e-55 187.7 13.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 CCL99495.1 - 2.8e-06 27.1 35.6 1.3e-05 25.0 18.3 3.1 1 1 2 3 3 3 2 Right handed beta helix region F-box PF00646.28 CCL99496.1 - 8.7e-05 22.0 0.0 0.0003 20.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain p450 PF00067.17 CCL99497.1 - 2.7e-70 237.2 0.0 3e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glycos_transf_2 PF00535.21 CCL99498.1 - 4e-24 85.1 0.0 5.1e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCL99498.1 - 2.2e-13 50.5 0.1 7.9e-13 48.7 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CCL99498.1 - 0.015 14.3 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CCL99498.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 F-box-like PF12937.2 CCL99501.1 - 0.015 15.0 0.1 0.041 13.5 0.1 1.8 1 0 0 1 1 1 0 F-box-like DAO PF01266.19 CCL99502.1 - 2.2e-45 155.1 0.6 2.8e-45 154.7 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCL99502.1 - 0.00062 19.8 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCL99502.1 - 0.0011 18.8 0.1 0.0029 17.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCL99502.1 - 0.0092 15.1 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CCL99502.1 - 0.093 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4572 PF15139.1 CCL99503.1 - 0.0057 16.5 0.2 0.0081 16.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) DUF1793 PF08760.6 CCL99504.1 - 1.8e-13 50.6 0.1 2.4e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Herpes_gE PF02480.11 CCL99504.1 - 0.0047 15.2 0.2 0.011 14.0 0.0 1.5 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E Ribosomal_S11 PF00411.14 CCL99505.1 - 2.9e-41 140.0 0.5 3.8e-41 139.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Acyltransferase PF01553.16 CCL99506.1 - 6.3e-14 51.5 0.0 9.6e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase zf-RING_5 PF14634.1 CCL99508.1 - 1.5e-08 34.1 12.1 3.5e-08 33.0 8.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCL99508.1 - 3.6e-08 33.1 13.0 8.7e-08 31.8 9.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CCL99508.1 - 4.4e-06 26.3 2.3 9.4e-06 25.2 0.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CCL99508.1 - 3.2e-05 23.8 12.5 7.1e-05 22.7 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCL99508.1 - 0.00031 20.3 12.0 0.00068 19.2 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCL99508.1 - 0.00052 19.8 9.0 0.0016 18.2 6.3 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 CCL99508.1 - 0.0027 17.1 3.4 0.0078 15.6 2.4 1.8 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-RING_4 PF14570.1 CCL99508.1 - 0.035 13.6 10.5 0.09 12.3 7.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CCL99508.1 - 0.04 13.4 9.5 0.087 12.3 6.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 CCL99508.1 - 0.24 11.2 7.1 0.55 10.1 4.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.2 CCL99508.1 - 3.2 7.9 8.5 8.4 6.5 5.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Glycos_transf_2 PF00535.21 CCL99509.1 - 1.1e-28 100.0 0.0 1.4e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCL99509.1 - 1.8e-10 40.9 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CCL99509.1 - 8.4e-08 31.6 0.0 1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CCL99509.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Synaptobrevin PF00957.16 CCL99510.1 - 4.9e-29 99.7 0.3 7.4e-29 99.1 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CCL99510.1 - 3.4e-22 77.7 0.0 6.7e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain ClpB_D2-small PF10431.4 CCL99510.1 - 0.076 12.9 0.2 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein DUF1675 PF07897.6 CCL99511.1 - 0.38 10.5 9.3 0.78 9.5 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Peptidase_S10 PF00450.17 CCL99512.1 - 8.5e-96 321.6 0.7 1.2e-95 321.1 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase F-box-like PF12937.2 CCL99512.1 - 0.2 11.3 3.1 0.15 11.7 0.7 1.9 2 0 0 2 2 2 0 F-box-like Leu_leader PF08054.6 CCL99512.1 - 9.1 6.0 7.1 1.7 8.3 1.6 2.3 3 0 0 3 3 3 0 Leucine operon leader peptide Hemerythrin PF01814.18 CCL99513.1 - 1.5e-05 25.1 0.1 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Fer2_3 PF13085.1 CCL99515.1 - 1.3e-32 111.8 0.1 1.9e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CCL99515.1 - 0.00013 22.1 0.1 0.00013 22.1 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CCL99515.1 - 0.0012 18.5 1.3 0.0024 17.5 0.9 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.1 CCL99515.1 - 0.0029 17.9 0.9 0.0047 17.3 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CCL99515.1 - 0.037 14.0 5.7 0.036 14.1 2.9 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Lung_7-TM_R PF06814.8 CCL99516.1 - 0.0064 15.4 4.1 0.0088 15.0 2.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Tetraspannin PF00335.15 CCL99516.1 - 1.7 7.9 13.0 2.2e+02 0.9 9.0 2.1 1 1 0 1 1 1 0 Tetraspanin family COesterase PF00135.23 CCL99517.1 - 1.5e-09 37.1 0.1 1.6e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family p450 PF00067.17 CCL99518.1 - 1.5e-72 244.6 0.0 3.9e-72 243.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCL99519.1 - 5.4e-71 239.4 0.0 1.9e-70 237.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCL99520.1 - 7.2e-66 222.6 0.0 2.9e-65 220.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 CCL99521.1 - 3e-44 151.1 0.0 6e-33 114.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99521.1 - 7.4e-27 94.0 0.0 3.5e-23 82.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCL99521.1 - 0.0003 19.8 0.0 0.2 10.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 CCL99521.1 - 0.0016 17.3 0.0 0.0024 16.7 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CCL99521.1 - 0.004 16.9 0.1 0.0071 16.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCL99521.1 - 0.036 13.4 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family p450 PF00067.17 CCL99522.1 - 8.9e-66 222.2 0.0 3.2e-65 220.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 PLDc_2 PF13091.1 CCL99523.1 - 3e-16 59.3 0.0 1.2e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CCL99523.1 - 0.00023 20.8 0.5 0.24 11.2 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF1488 PF07369.6 CCL99525.1 - 0.04 13.7 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) Mit_ribos_Mrp51 PF11709.3 CCL99527.1 - 2.9e-17 62.8 0.5 1.8e-16 60.2 0.4 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF4570 PF15134.1 CCL99527.1 - 0.042 13.6 0.1 0.042 13.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Proteasome PF00227.21 CCL99528.1 - 2.9e-32 111.5 0.0 4e-32 111.0 0.0 1.3 1 1 0 1 1 1 1 Proteasome subunit Rot1 PF10681.4 CCL99529.1 - 1.2e-52 178.3 1.5 1.4e-52 178.1 1.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF3300 PF11737.3 CCL99529.1 - 0.057 12.6 0.2 0.097 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) Aldo_ket_red PF00248.16 CCL99530.1 - 1e-52 178.7 0.0 1.2e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HisG PF01634.13 CCL99531.1 - 2e-49 167.2 0.2 3.5e-49 166.5 0.2 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CCL99531.1 - 1.1e-26 92.5 0.0 2.9e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 CCL99531.1 - 2.4e-05 24.0 0.1 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Clat_adaptor_s PF01217.15 CCL99532.1 - 1.7e-52 176.9 4.9 8.9e-52 174.5 3.4 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain UQ_con PF00179.21 CCL99533.1 - 1.5e-41 141.1 0.0 1.8e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 CCL99533.1 - 1.1e-19 69.8 0.2 1.7e-19 69.1 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 CCL99533.1 - 0.0001 22.0 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B FeoA PF04023.9 CCL99533.1 - 0.046 13.6 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 FeoA domain ArfGap PF01412.13 CCL99534.1 - 5.5e-34 116.4 1.3 6.4e-34 116.2 0.2 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf SR-25 PF10500.4 CCL99534.1 - 0.052 13.0 9.9 0.11 12.0 6.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein A2L_zn_ribbon PF08792.5 CCL99534.1 - 0.59 9.6 2.8 1.7 8.1 1.9 1.7 1 1 1 2 2 2 0 A2L zinc ribbon domain Pkinase PF00069.20 CCL99535.1 - 1.1e-26 93.5 0.0 1.7e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99535.1 - 1.5e-11 43.8 0.0 2.7e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pribosyltran_N PF13793.1 CCL99537.1 - 3e-43 146.2 0.3 9.5e-42 141.4 0.1 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCL99537.1 - 1e-39 136.1 0.8 3.7e-34 118.0 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCL99537.1 - 1.1e-11 44.5 0.1 6.9e-11 41.9 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCL99537.1 - 0.017 14.3 0.1 0.033 13.3 0.1 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TIM PF00121.13 CCL99537.1 - 0.032 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Triosephosphate isomerase DCP2 PF05026.8 CCL99538.1 - 8e-34 115.4 1.7 1.4e-33 114.6 1.2 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 CCL99538.1 - 4.3e-12 45.8 0.0 7.2e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GNAT_acetyltr_2 PF13718.1 CCL99539.1 - 2e-74 249.2 0.0 3.5e-74 248.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CCL99539.1 - 3.8e-65 218.8 1.0 7.8e-65 217.7 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 CCL99539.1 - 7.7e-39 131.2 0.1 1.9e-38 130.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CCL99539.1 - 5.4e-33 113.1 2.4 1.2e-32 112.0 0.9 2.3 2 0 0 2 2 2 1 Possible tRNA binding domain Rad21_Rec8_N PF04825.8 CCL99539.1 - 5.3e-20 71.4 0.0 1.3e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein GRAM PF02893.15 CCL99539.1 - 0.0014 18.1 0.1 0.0061 16.0 0.0 2.1 2 0 0 2 2 2 1 GRAM domain Acetyltransf_7 PF13508.1 CCL99539.1 - 0.0037 17.3 0.0 0.032 14.3 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3292 PF11696.3 CCL99539.1 - 0.056 11.3 2.4 0.086 10.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) NUDIX PF00293.23 CCL99540.1 - 8.4e-26 90.2 0.0 1.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF2360 PF10152.4 CCL99541.1 - 0.18 12.0 2.9 0.19 11.9 2.0 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Sporozoite_P67 PF05642.6 CCL99541.1 - 0.3 8.9 10.2 0.35 8.6 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 CCL99541.1 - 0.32 10.2 4.8 0.4 9.8 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein TFIIF_alpha PF05793.7 CCL99541.1 - 1.9 6.7 9.8 2.3 6.4 6.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF566 PF04484.7 CCL99541.1 - 4.3 6.7 9.0 4.9 6.5 6.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MSA-2c PF12238.3 CCL99541.1 - 6.7 6.3 11.4 10 5.7 7.9 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF605 PF04652.11 CCL99541.1 - 8 5.7 18.6 9.1 5.5 12.9 1.0 1 0 0 1 1 1 0 Vta1 like MPC PF03650.8 CCL99544.1 - 5e-39 132.9 0.4 5.4e-39 132.8 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DNA_ligase_A_M PF01068.16 CCL99545.1 - 2.5e-62 209.8 0.2 4e-62 209.1 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCL99545.1 - 2e-53 180.8 0.5 3.4e-53 180.0 0.3 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CCL99545.1 - 1.2e-26 92.8 0.0 3.4e-26 91.4 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CCL99545.1 - 0.015 14.9 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Salp15 PF12115.3 CCL99545.1 - 0.056 13.6 0.0 0.71 10.1 0.0 2.4 1 1 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF3386 PF11866.3 CCL99547.1 - 0.065 12.4 0.3 0.11 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) Ricin_B_lectin PF00652.17 CCL99547.1 - 0.075 13.0 0.1 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain CHAP PF05257.11 CCL99548.1 - 0.046 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 CHAP domain PSDC PF12588.3 CCL99549.1 - 1.4e-47 160.8 0.1 2.4e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 CCL99549.1 - 1.5e-35 122.3 0.0 1.9e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AA_permease_2 PF13520.1 CCL99550.1 - 1.3e-52 178.8 54.6 1.5e-52 178.5 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCL99550.1 - 6.8e-15 54.3 49.1 9.7e-15 53.8 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease Patatin PF01734.17 CCL99550.1 - 0.19 11.6 3.6 0.54 10.1 0.3 2.3 2 0 0 2 2 2 0 Patatin-like phospholipase Polysacc_deac_1 PF01522.16 CCL99551.1 - 0.019 14.5 0.1 0.1 12.2 0.1 2.2 1 1 0 1 1 1 0 Polysaccharide deacetylase Abhydrolase_6 PF12697.2 CCL99552.1 - 2.3e-15 57.1 2.9 2.9e-15 56.7 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCL99552.1 - 0.016 14.9 0.1 0.086 12.5 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family AA_permease PF00324.16 CCL99553.1 - 1.2e-114 383.2 44.4 1.5e-114 382.9 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCL99553.1 - 3.4e-46 157.6 45.6 4.2e-46 157.3 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease HET PF06985.6 CCL99554.1 - 2.1e-15 57.0 4.5 4.5e-14 52.8 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GST_N PF02798.15 CCL99555.1 - 1.8e-14 53.6 0.0 1e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCL99555.1 - 6.4e-13 48.4 0.0 2.2e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCL99555.1 - 1.5e-12 47.3 0.1 2.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCL99555.1 - 6.4e-12 45.5 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCL99555.1 - 6.6e-06 26.5 0.1 1.3e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCL99555.1 - 2.5e-05 24.0 0.0 5.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCL99556.1 - 4.3e-14 52.2 0.0 7.5e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCL99556.1 - 5.9e-09 36.0 0.0 9.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCL99556.1 - 1.3e-08 34.7 0.1 3.6e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCL99556.1 - 2.1e-07 31.0 0.0 4.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCL99556.1 - 3e-07 30.2 0.1 6.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCL99556.1 - 4.6e-05 23.8 0.0 7.7e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4131 PF13567.1 CCL99557.1 - 0.45 9.9 7.6 0.18 11.2 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 CCL99558.1 - 1.3e-27 96.4 25.9 1.9e-23 82.7 8.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M41 PF01434.13 CCL99559.1 - 3.5e-72 242.3 0.1 1.2e-71 240.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 CCL99559.1 - 1.9e-42 144.5 0.0 3.5e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CCL99559.1 - 5.4e-13 49.0 0.2 1.6e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 FtsH Extracellular AAA_17 PF13207.1 CCL99559.1 - 0.0016 19.2 0.1 0.005 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CCL99559.1 - 0.0023 18.0 0.0 0.069 13.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCL99559.1 - 0.0024 17.5 0.0 0.011 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCL99559.1 - 0.0038 16.9 0.4 0.012 15.3 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 CCL99559.1 - 0.0046 15.7 0.0 0.0078 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CCL99559.1 - 0.0057 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CCL99559.1 - 0.0059 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCL99559.1 - 0.017 15.0 0.1 0.072 13.0 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 CCL99559.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 CCL99559.1 - 0.033 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCL99559.1 - 0.04 13.3 0.6 0.23 10.8 0.2 2.4 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CCL99559.1 - 0.053 12.6 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin His_Phos_2 PF00328.17 CCL99560.1 - 1e-33 117.1 0.0 1.7e-33 116.4 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PP2C PF00481.16 CCL99561.1 - 6e-33 114.2 0.0 1e-31 110.2 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CCL99561.1 - 0.0016 17.9 0.0 0.0038 16.6 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C G_glu_transpept PF01019.16 CCL99562.1 - 3.5e-08 32.4 0.0 3.7e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.16 CCL99563.1 - 5.2e-115 384.8 0.0 6.7e-115 384.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF2835 PF11197.3 CCL99563.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Fungal_trans PF04082.13 CCL99564.1 - 0.0033 16.3 0.2 0.037 12.9 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 CCL99565.1 - 1.9e-27 95.9 52.9 2e-25 89.3 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EXS PF03124.9 CCL99566.1 - 9.8e-81 271.4 24.7 1.2e-80 271.1 17.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CCL99566.1 - 8.3e-41 140.5 0.0 1.4e-40 139.8 0.0 1.3 1 0 0 1 1 1 1 SPX domain RmlD_sub_bind PF04321.12 CCL99566.1 - 1.5e-32 112.6 0.0 2.7e-21 75.7 0.0 2.2 1 1 1 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.16 CCL99566.1 - 4.4e-11 42.6 0.0 1.1e-06 28.3 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CCL99566.1 - 0.16 10.8 0.0 3.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein LSM PF01423.17 CCL99568.1 - 2.3e-15 55.9 0.1 2.8e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Glyco_hydro_28 PF00295.12 CCL99569.1 - 7.4e-37 127.0 14.7 2e-34 118.9 10.2 2.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 TPT PF03151.11 CCL99570.1 - 1.2e-22 80.2 8.4 1.2e-22 80.2 5.8 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 CCL99570.1 - 0.0053 16.9 21.1 0.012 15.8 3.3 2.7 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 CCL99570.1 - 0.006 16.6 7.0 0.006 16.6 4.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CCL99570.1 - 0.0067 15.3 14.3 0.045 12.6 4.3 2.1 2 0 0 2 2 2 2 UAA transporter family DUF3849 PF12960.2 CCL99571.1 - 0.025 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) Glyco_hydro_28 PF00295.12 CCL99573.1 - 5.5e-53 180.0 9.1 8.1e-53 179.4 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TENA_THI-4 PF03070.11 CCL99574.1 - 9.8e-12 45.0 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Sec2p PF06428.6 CCL99575.1 - 3e-14 52.6 10.9 3e-14 52.6 7.6 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.6 CCL99575.1 - 0.013 15.3 1.8 0.013 15.3 1.3 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Herpes_UL6 PF01763.11 CCL99575.1 - 0.082 11.0 5.3 0.2 9.7 0.5 2.1 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF4200 PF13863.1 CCL99575.1 - 0.22 11.4 14.2 0.78 9.6 8.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Filament PF00038.16 CCL99575.1 - 1.2 8.5 18.6 0.93 8.9 1.1 3.2 1 1 2 3 3 3 0 Intermediate filament protein AAA_13 PF13166.1 CCL99575.1 - 7.9 4.8 11.1 0.53 8.6 2.4 1.9 1 1 0 1 1 1 0 AAA domain SIS PF01380.17 CCL99576.1 - 2e-61 205.3 0.1 1.2e-31 108.9 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CCL99576.1 - 4.6e-23 81.4 0.2 4e-17 61.9 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCL99576.1 - 5.2e-18 65.2 0.0 9.9e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCL99576.1 - 2.2e-12 46.7 0.0 4.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCL99576.1 - 5e-08 31.9 0.0 7e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CCL99576.1 - 0.0025 17.5 0.0 0.025 14.2 0.0 2.4 1 1 0 2 2 2 1 SIS domain G-patch_2 PF12656.2 CCL99577.1 - 1.9e-27 94.9 0.2 5e-26 90.3 0.0 2.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 CCL99577.1 - 0.0026 17.5 0.1 0.0058 16.4 0.1 1.7 1 0 0 1 1 1 1 G-patch domain DUF485 PF04341.7 CCL99579.1 - 0.012 15.2 1.6 0.012 15.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 p450 PF00067.17 CCL99580.1 - 2.2e-64 217.6 0.0 9.1e-64 215.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Rtt106 PF08512.7 CCL99582.1 - 0.13 12.2 0.2 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Histone chaperone Rttp106-like YwiC PF14256.1 CCL99582.1 - 4.1 7.4 8.6 0.11 12.5 1.6 1.5 2 0 0 2 2 2 0 YwiC-like protein TPR_10 PF13374.1 CCL99583.1 - 1.4 9.0 5.8 2.2 8.3 3.1 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.11 CCL99584.1 - 2.7e-14 52.6 51.6 4.2e-13 48.7 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CsbD PF05532.7 CCL99584.1 - 0.17 11.5 5.2 0.37 10.4 3.6 1.5 1 0 0 1 1 1 0 CsbD-like Sec23_trunk PF04811.10 CCL99585.1 - 6.1e-72 241.8 0.0 1.6e-71 240.5 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCL99585.1 - 5.4e-23 80.3 0.2 2.9e-22 78.0 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCL99585.1 - 5.5e-18 65.2 0.1 1.3e-17 64.1 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCL99585.1 - 8.7e-17 60.4 8.1 1.6e-16 59.5 5.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCL99585.1 - 2.6e-09 36.6 0.0 5.5e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 CCL99585.1 - 5.4e-06 26.1 0.4 5.4e-06 26.1 0.3 2.2 2 0 0 2 2 2 1 WW domain ELYS PF13934.1 CCL99586.1 - 3.6e-48 164.2 0.0 5.3e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly Ribosomal_S5_C PF03719.10 CCL99587.1 - 7.6e-18 63.5 0.0 1.8e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CCL99587.1 - 4e-13 48.8 0.7 1.1e-12 47.5 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain PITH PF06201.8 CCL99588.1 - 5.3e-35 120.4 0.0 6.5e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Pkinase PF00069.20 CCL99589.1 - 2.1e-56 190.9 0.0 3e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99589.1 - 6.6e-32 110.5 0.0 9.3e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCL99589.1 - 0.0015 17.4 0.1 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 CCL99589.1 - 0.04 13.6 0.1 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CCL99589.1 - 0.17 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Transp_cyt_pur PF02133.10 CCL99590.1 - 2e-101 339.7 35.8 2.3e-101 339.5 24.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ATP-synt_10 PF05176.9 CCL99591.1 - 1.2e-70 237.7 0.0 1.5e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein TYW3 PF02676.9 CCL99591.1 - 0.021 13.9 0.1 0.036 13.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF4539 PF15072.1 CCL99593.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) WD40 PF00400.27 CCL99595.1 - 2.1e-53 176.3 16.6 6.2e-13 48.0 0.0 11.8 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.7 CCL99595.1 - 2.7e-21 75.5 0.0 4.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 CCL99595.1 - 5.4e-05 23.0 0.2 2.8 7.6 0.0 4.8 4 3 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CCL99595.1 - 0.001 18.5 1.1 0.084 12.3 0.1 3.4 2 1 2 4 4 4 1 PQQ-like domain Cytochrom_D1 PF02239.11 CCL99595.1 - 0.0018 16.6 0.1 6.1 5.0 0.0 3.7 4 0 0 4 4 4 2 Cytochrome D1 heme domain DUF1513 PF07433.6 CCL99595.1 - 0.0019 17.1 0.0 4 6.2 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1513) SGL PF08450.7 CCL99595.1 - 0.0041 16.5 0.0 5.2 6.3 0.0 3.1 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region PH_6 PF15406.1 CCL99595.1 - 0.012 15.6 0.0 0.73 9.9 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain TFIIIC_delta PF12657.2 CCL99595.1 - 0.066 12.9 0.0 2.4 7.8 0.0 2.6 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term RAB3GAP2_N PF14655.1 CCL99595.1 - 0.09 11.7 0.1 2 7.3 0.0 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus OPT PF03169.10 CCL99596.1 - 2.7e-123 412.5 43.9 4e-123 412.0 30.4 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 CCL99597.1 - 2.2e-10 39.6 1.8 2.5e-10 39.4 1.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TctB PF07331.6 CCL99597.1 - 0.014 15.0 0.5 0.019 14.5 0.3 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2149 PF09919.4 CCL99597.1 - 0.24 11.5 0.1 0.24 11.5 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) YWFCY PF14293.1 CCL99597.1 - 0.4 10.5 1.5 0.92 9.4 1.1 1.6 1 1 0 1 1 1 0 YWFCY protein Sugar_tr PF00083.19 CCL99598.1 - 1.3e-86 290.9 28.0 1.5e-86 290.7 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCL99598.1 - 1.5e-26 92.9 55.5 3.7e-25 88.3 20.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCL99598.1 - 0.00031 19.2 3.2 0.00031 19.2 2.2 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein Vif PF00559.12 CCL99600.1 - 0.1 12.4 0.1 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral Vif (Viral infectivity) protein RRM_1 PF00076.17 CCL99601.1 - 3.6e-12 45.7 0.0 5.9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL99601.1 - 2.9e-07 30.3 0.0 5.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CCL99601.1 - 1e-05 25.8 0.2 2.6e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 CCL99601.1 - 0.00046 19.9 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HlyIII PF03006.15 CCL99603.1 - 9.8e-28 97.0 19.0 5e-14 52.2 2.8 2.1 2 0 0 2 2 2 2 Haemolysin-III related DUF2207 PF09972.4 CCL99603.1 - 0.027 13.0 0.5 0.064 11.8 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) p450 PF00067.17 CCL99604.1 - 5e-31 107.7 0.0 2.6e-30 105.3 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 TPIP1 PF15338.1 CCL99604.1 - 0.041 13.7 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 Neugrin PF06413.6 CCL99605.1 - 2.3e-12 47.2 1.5 3.3e-12 46.7 1.0 1.3 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 CCL99605.1 - 0.0031 17.5 9.5 0.007 16.3 6.6 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 UPF0240 PF06784.6 CCL99605.1 - 0.03 14.0 0.8 0.038 13.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) Cofilin_ADF PF00241.15 CCL99606.1 - 1.6e-18 66.7 0.1 1.8e-18 66.6 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Acetyltransf_1 PF00583.19 CCL99607.1 - 5e-15 55.3 0.0 8.1e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCL99607.1 - 0.00044 20.3 0.0 0.00059 19.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCL99607.1 - 0.00071 19.7 0.0 0.001 19.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCL99607.1 - 0.00074 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCL99607.1 - 0.088 12.7 0.0 0.24 11.3 0.0 1.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain NAC PF01849.13 CCL99608.1 - 3.7e-16 58.3 0.8 2.4e-13 49.3 0.1 2.3 2 0 0 2 2 2 2 NAC domain WD40 PF00400.27 CCL99609.1 - 2.3e-43 144.5 33.0 1.1e-09 37.7 1.7 10.8 11 1 1 12 12 12 8 WD domain, G-beta repeat eIF2A PF08662.6 CCL99609.1 - 7.9e-08 32.2 1.0 0.0018 18.0 0.0 3.7 3 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CCL99609.1 - 0.00062 18.9 1.1 1.8 7.6 0.0 3.3 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 CCL99609.1 - 0.0014 16.6 0.1 0.024 12.4 0.0 2.2 2 0 0 2 2 2 1 IKI3 family PD40 PF07676.7 CCL99609.1 - 0.016 14.8 0.6 0.93 9.2 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CPSF_A PF03178.10 CCL99609.1 - 0.045 12.8 0.0 4.9 6.1 0.0 2.8 3 0 0 3 3 3 0 CPSF A subunit region Kelch_6 PF13964.1 CCL99609.1 - 0.049 13.8 0.3 1.7 8.9 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Mad3_BUB1_I PF08311.7 CCL99610.1 - 1.2e-28 99.4 0.0 1.7e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 ECH PF00378.15 CCL99610.1 - 0.0063 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MFS_1 PF07690.11 CCL99611.1 - 2.5e-29 102.0 31.8 2.5e-29 102.0 22.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily AlcCBM31 PF11606.3 CCL99611.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein RRM_1 PF00076.17 CCL99612.1 - 2.3e-30 104.0 0.0 1.3e-10 40.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL99612.1 - 2.2e-17 62.7 0.0 1.9e-07 30.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL99612.1 - 4.4e-09 36.0 0.0 0.0075 16.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CCL99612.1 - 3e-06 26.8 2.5 0.0003 20.3 0.0 3.2 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Sterol_MT_C PF08498.5 CCL99613.1 - 6.4e-24 83.6 0.0 9.4e-24 83.1 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 CCL99613.1 - 2.6e-17 62.7 0.0 3.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCL99613.1 - 5.2e-16 58.9 0.0 8.5e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCL99613.1 - 3.5e-14 52.5 0.0 5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CCL99613.1 - 6.5e-12 46.0 0.0 2.1e-11 44.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCL99613.1 - 1.8e-11 44.0 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCL99613.1 - 1.2e-10 41.7 0.2 2.1e-10 40.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCL99613.1 - 3.5e-10 39.9 0.0 1.3e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCL99613.1 - 3.8e-10 40.0 0.0 7.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCL99613.1 - 1.3e-07 31.0 0.0 2.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 CCL99613.1 - 5.6e-05 22.2 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_15 PF09445.5 CCL99613.1 - 0.00017 21.1 0.1 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 CCL99613.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CCL99613.1 - 0.0005 19.5 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 CCL99613.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 CCL99613.1 - 0.0058 17.4 0.0 0.015 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CCL99613.1 - 0.0059 16.2 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 CCL99613.1 - 0.072 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Met_10 PF02475.11 CCL99613.1 - 0.072 12.6 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein NMT1 PF09084.6 CCL99613.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 NMT1/THI5 like Mob_Pre PF01076.14 CCL99613.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Methyltransf_32 PF13679.1 CCL99613.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 2 0 0 2 2 1 0 Methyltransferase domain PCI PF01399.22 CCL99614.1 - 1.1e-21 77.0 0.1 6.7e-21 74.5 0.0 2.3 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 CCL99614.1 - 2.6e-18 66.1 0.3 2.6e-18 66.1 0.2 2.7 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal Helicase_C_3 PF13625.1 CCL99614.1 - 0.058 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain OKR_DC_1_C PF03711.10 CCL99614.1 - 0.087 12.8 0.0 2.3 8.2 0.0 2.7 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, C-terminal domain TPR_12 PF13424.1 CCL99614.1 - 1.3 9.0 7.1 5.4 7.0 1.1 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCL99614.1 - 3.3 8.4 12.6 0.54 11.0 0.5 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Profilin PF00235.14 CCL99615.1 - 3e-39 133.8 0.1 3.3e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Profilin Ribophorin_II PF05817.9 CCL99616.1 - 7.6e-25 87.1 0.1 9.6e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyco_hydro_47 PF01532.15 CCL99617.1 - 1.5e-116 389.7 0.7 1.7e-116 389.5 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 F-box-like PF12937.2 CCL99618.1 - 0.0024 17.5 0.2 0.0071 16.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like APG9 PF04109.11 CCL99619.1 - 4.2e-162 539.2 0.5 5.5e-162 538.8 0.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 PLDc_2 PF13091.1 CCL99620.1 - 1.3e-08 34.6 0.0 0.0031 17.2 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CCL99620.1 - 0.00053 19.7 0.9 1.2 9.0 0.0 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif Nab1 PF04902.7 CCL99620.1 - 0.1 12.1 0.2 0.77 9.2 0.1 2.2 2 0 0 2 2 2 0 Conserved region in Nab1 Pro_isomerase PF00160.16 CCL99621.1 - 1.6e-50 171.3 0.0 2e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CCL99622.1 - 1.5e-45 151.4 19.5 4.1e-10 39.1 0.3 7.3 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CCL99622.1 - 6e-09 34.5 1.9 0.3 9.1 0.0 4.2 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCL99622.1 - 9.8e-05 21.2 0.0 1.9 7.1 0.0 4.4 2 2 2 5 5 5 2 Nup133 N terminal like PQQ_2 PF13360.1 CCL99622.1 - 0.00016 21.2 0.6 0.14 11.5 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 CCL99622.1 - 0.00045 20.4 4.5 0.64 10.3 0.0 5.7 6 1 0 6 6 6 1 PQQ-like domain WD40 PF00400.27 CCL99623.1 - 1.7e-56 186.2 25.2 5.8e-11 41.8 0.4 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 CCL99623.1 - 3.8e-12 45.7 1.1 3.8e-12 45.7 0.8 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCL99623.1 - 8.2e-11 41.2 1.3 2.3e-10 39.8 0.9 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 CCL99623.1 - 2.7e-05 22.5 15.0 0.23 9.5 0.1 5.8 3 3 3 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCL99623.1 - 0.00035 19.4 1.2 4.1 6.0 0.1 4.6 2 2 2 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 CCL99623.1 - 0.0015 18.0 4.6 5.5 6.3 0.0 3.5 3 1 1 4 4 4 3 PQQ-like domain Fungal_trans PF04082.13 CCL99624.1 - 3.5e-14 52.3 0.5 7.3e-14 51.2 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCL99624.1 - 4.3e-05 23.3 7.5 4.3e-05 23.3 5.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1459 PF07312.6 CCL99625.1 - 0.42 10.5 3.5 0.97 9.3 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) GDA1_CD39 PF01150.12 CCL99627.1 - 3.3e-102 342.2 0.0 8.3e-95 317.8 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CCL99627.1 - 0.0033 16.6 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Radical_SAM PF04055.16 CCL99628.1 - 2.8e-16 60.1 0.1 1e-15 58.2 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CCL99628.1 - 1.2e-11 44.5 0.1 3.2e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCL99628.1 - 0.0037 17.3 0.0 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCL99628.1 - 0.038 13.7 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein DUF2404 PF10296.4 CCL99629.1 - 0.00012 22.1 0.0 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Nuc_sug_transp PF04142.10 CCL99630.1 - 5.6e-77 258.1 4.1 8.9e-77 257.4 2.9 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 CCL99630.1 - 4e-08 33.4 3.7 4e-08 33.4 2.6 3.0 2 2 1 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 CCL99630.1 - 1.1e-06 27.7 7.4 1.8e-06 27.1 5.1 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCL99630.1 - 1.7e-05 24.4 3.1 1.7e-05 24.4 2.2 3.1 2 2 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CCL99630.1 - 0.00026 21.0 24.5 0.0041 17.1 4.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family Mit_ribos_Mrp51 PF11709.3 CCL99631.1 - 1.2e-16 60.8 1.0 6.7e-16 58.4 0.7 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF4570 PF15134.1 CCL99631.1 - 0.0056 16.5 0.1 0.0056 16.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4570) UPF1_Zn_bind PF09416.5 CCL99633.1 - 2.4e-70 235.0 3.2 4.6e-70 234.0 2.2 1.5 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CCL99633.1 - 1e-58 198.0 0.0 1.7e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCL99633.1 - 6.2e-56 189.6 2.3 9.5e-56 189.0 1.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCL99633.1 - 4.9e-14 51.8 0.8 1.4e-13 50.4 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CCL99633.1 - 3.5e-13 49.5 0.3 4.3e-12 46.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CCL99633.1 - 1.1e-07 31.9 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 CCL99633.1 - 7.5e-07 28.9 0.1 0.035 13.6 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CCL99633.1 - 3.6e-06 26.2 0.0 5.3e-05 22.3 0.0 2.6 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 CCL99633.1 - 0.00013 21.6 0.1 0.0003 20.4 0.1 1.7 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 CCL99633.1 - 0.00014 21.3 0.2 0.0019 17.5 0.1 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Ribosomal_S13_N PF08069.7 CCL99633.1 - 0.00043 20.0 0.1 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain DEAD PF00270.24 CCL99633.1 - 0.0028 17.1 0.3 0.0063 16.0 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 CCL99633.1 - 0.027 13.7 0.1 0.09 11.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.9 CCL99633.1 - 0.044 12.7 0.1 0.56 9.0 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_25 PF13481.1 CCL99633.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCL99633.1 - 0.058 13.5 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 CCL99633.1 - 0.095 11.8 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC SRP54 PF00448.17 CCL99633.1 - 0.11 11.9 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Erf4 PF10256.4 CCL99635.1 - 6.9e-28 96.8 0.1 9.5e-28 96.4 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family bZIP_1 PF00170.16 CCL99636.1 - 1.2e-11 44.3 14.6 2e-11 43.6 10.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 CCL99636.1 - 1.1e-09 38.4 0.0 1.1e-09 38.4 0.0 4.1 2 1 1 3 3 3 1 Transcription factor PAP1 Tmemb_cc2 PF10267.4 CCL99636.1 - 0.00012 20.7 0.1 0.00012 20.7 0.1 2.2 3 0 0 3 3 3 1 Predicted transmembrane and coiled-coil 2 protein DivIC PF04977.10 CCL99636.1 - 0.00098 18.5 1.4 0.002 17.5 1.0 1.5 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.10 CCL99636.1 - 0.0013 18.5 14.4 0.0013 18.5 9.9 2.2 1 1 1 2 2 2 1 Basic region leucine zipper Glutaredoxin2_C PF04399.8 CCL99636.1 - 0.2 11.2 2.0 0.35 10.4 1.4 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain TSC22 PF01166.13 CCL99636.1 - 0.37 10.7 3.9 2 8.4 2.7 2.2 1 1 0 1 1 1 0 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.4 CCL99636.1 - 0.41 10.6 7.5 0.7 9.8 5.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 GvpL_GvpF PF06386.6 CCL99636.1 - 0.57 9.7 4.0 0.86 9.1 2.8 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF724 PF05266.9 CCL99636.1 - 1.2 8.6 8.7 1.4 8.5 4.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ArsA_ATPase PF02374.10 CCL99637.1 - 6.5e-109 363.6 0.8 7.8e-109 363.4 0.5 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CCL99637.1 - 1e-13 51.1 0.0 1.9e-13 50.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CCL99637.1 - 2.1e-08 34.2 0.0 4.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CCL99637.1 - 1.5e-05 24.3 0.1 3.5e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CCL99637.1 - 2.4e-05 23.8 0.3 0.0003 20.2 0.1 2.2 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CCL99637.1 - 0.00039 19.8 0.2 0.0017 17.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCL99637.1 - 0.0012 18.5 0.0 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain YhjQ PF06564.7 CCL99637.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 YhjQ protein IstB_IS21 PF01695.12 CCL99637.1 - 0.0074 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein MipZ PF09140.6 CCL99637.1 - 0.02 13.9 0.1 0.044 12.8 0.1 1.7 1 1 0 1 1 1 0 ATPase MipZ FtsK_SpoIIIE PF01580.13 CCL99637.1 - 0.027 13.9 0.1 0.07 12.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 CCL99637.1 - 0.029 13.9 0.0 0.065 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CCL99637.1 - 0.039 13.3 0.0 0.09 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain KaiC PF06745.8 CCL99637.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 CCL99637.1 - 0.076 11.9 0.1 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 CCL99637.1 - 0.17 12.0 0.2 0.61 10.2 0.1 2.0 2 1 0 2 2 1 0 AAA domain TPR_10 PF13374.1 CCL99638.1 - 1.1 9.3 4.1 3.4 7.7 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.18 CCL99639.1 - 1.8e-83 279.7 0.5 3.3e-83 278.9 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 CCL99639.1 - 1e-24 86.2 0.1 3.2e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 CCL99639.1 - 1.6e-15 56.6 3.9 3.6e-15 55.5 0.0 3.5 5 0 0 5 5 5 1 Helicase conserved C-terminal domain HSA PF07529.8 CCL99639.1 - 3.2e-14 52.4 5.7 1.1e-13 50.7 4.0 2.0 1 0 0 1 1 1 1 HSA SnAC PF14619.1 CCL99639.1 - 5.5e-14 52.0 0.4 5.5e-14 52.0 0.3 3.6 2 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 CCL99639.1 - 5.4e-10 38.5 0.9 5.4e-10 38.5 0.6 2.1 2 0 0 2 2 2 1 QLQ UNC119_bdg PF15435.1 CCL99639.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue Ribosomal_60s PF00428.14 CCL99639.1 - 0.066 13.6 0.1 0.066 13.6 0.1 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ku PF02735.11 CCL99640.1 - 1.2e-21 77.0 1.8 1.6e-21 76.6 0.0 2.1 2 1 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 CCL99640.1 - 1.3e-12 47.6 0.0 2.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 CCL99640.1 - 9.8e-08 31.6 0.0 2.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.23 CCL99640.1 - 7.8e-05 22.4 0.0 0.00021 21.0 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CCL99640.1 - 0.00018 21.6 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Pkinase PF00069.20 CCL99641.1 - 4.5e-34 117.7 0.0 7.5e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99641.1 - 1.4e-33 116.0 0.0 2.1e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCL99641.1 - 6.6e-05 22.0 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCL99641.1 - 0.0014 18.3 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCL99641.1 - 0.07 11.9 0.1 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 CCL99642.1 - 1.1e-09 37.7 0.0 6e-07 28.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99642.1 - 0.0013 17.8 0.0 0.055 12.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Exo_endo_phos PF03372.18 CCL99643.1 - 3.3e-21 76.3 0.1 5.8e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CCL99643.1 - 2.8e-17 61.9 12.0 3.1e-08 33.0 1.6 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCL99643.1 - 1.5e-16 59.9 25.5 1.7e-08 34.0 3.9 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CCL99643.1 - 3.4e-08 32.4 8.0 0.22 11.6 0.1 5.4 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CCL99643.1 - 9.3e-05 22.0 10.7 0.079 13.1 0.1 4.9 4 0 0 4 4 4 2 Leucine rich repeat Innate_immun PF12782.2 CCL99643.1 - 0.25 10.5 6.4 0.4 9.8 4.4 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family LRR_6 PF13516.1 CCL99643.1 - 2.3 8.5 6.6 98 3.5 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat GHMP_kinases_N PF00288.21 CCL99644.1 - 2.7e-08 33.7 4.7 6.2e-08 32.5 3.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cupin_2 PF07883.6 CCL99645.1 - 2e-14 52.8 0.5 3.3e-14 52.1 0.3 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CCL99645.1 - 4.7e-06 26.0 0.0 5.9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.13 CCL99645.1 - 1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.7 CCL99645.1 - 8.7e-05 21.8 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) GPI PF06560.6 CCL99645.1 - 0.0037 16.3 1.2 0.011 14.7 0.0 1.9 1 1 1 2 2 2 1 Glucose-6-phosphate isomerase (GPI) Cupin_6 PF12852.2 CCL99645.1 - 0.038 13.6 0.1 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.14 CCL99645.1 - 0.041 13.5 0.1 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF1573 PF07610.6 CCL99645.1 - 0.063 12.8 0.0 5.2 6.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) JmjC PF02373.17 CCL99645.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase Asp PF00026.18 CCL99647.1 - 2.4e-64 217.5 2.3 3e-64 217.2 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCL99647.1 - 2e-07 31.0 0.3 6.4e-07 29.4 0.2 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCL99647.1 - 0.0014 19.0 2.2 0.3 11.6 0.2 3.5 2 2 1 3 3 3 1 Aspartyl protease LDB19 PF13002.2 CCL99647.1 - 0.043 13.3 0.5 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Arrestin_N terminal like Asp PF00026.18 CCL99649.1 - 4.2e-65 220.0 3.9 5.2e-65 219.7 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCL99649.1 - 6.8e-08 32.6 1.0 6.8e-08 32.6 0.7 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCL99649.1 - 0.0012 18.4 0.1 0.0057 16.2 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TPR_11 PF13414.1 CCL99651.1 - 1.1e-25 89.0 35.2 2.8e-06 26.8 0.1 10.8 9 2 2 11 11 11 8 TPR repeat TPR_2 PF07719.12 CCL99651.1 - 2.3e-24 83.3 34.3 0.00014 21.5 0.1 13.3 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_19 PF14559.1 CCL99651.1 - 1e-23 83.4 34.3 4.9e-06 26.7 0.1 11.7 10 3 3 13 13 13 9 Tetratricopeptide repeat TPR_1 PF00515.23 CCL99651.1 - 2.4e-22 77.5 27.3 7.3e-05 22.2 0.1 11.2 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_12 PF13424.1 CCL99651.1 - 2.9e-19 68.7 32.9 2.5e-07 30.5 1.2 10.1 7 3 4 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.1 CCL99651.1 - 7.7e-17 60.2 36.4 0.0012 19.2 0.1 13.9 12 2 4 16 16 13 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCL99651.1 - 1e-14 54.7 46.7 0.0001 22.8 0.1 12.3 11 2 3 14 14 14 6 Tetratricopeptide repeat TPR_6 PF13174.1 CCL99651.1 - 2e-14 52.9 23.9 6e-05 23.2 0.2 10.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCL99651.1 - 1.3e-11 43.4 18.6 0.0031 17.1 0.1 10.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCL99651.1 - 1e-09 37.4 14.2 0.26 11.1 0.1 8.2 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 CCL99651.1 - 9.6e-09 35.2 22.4 0.1 12.7 0.0 6.8 5 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CCL99651.1 - 1.2e-08 34.4 21.2 2.1 8.7 0.0 10.5 12 1 1 13 13 11 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCL99651.1 - 0.0029 17.4 27.8 1 9.4 0.9 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_4 PF07721.9 CCL99651.1 - 0.28 11.7 0.0 0.28 11.7 0.0 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat SWIRM PF04433.12 CCL99652.1 - 1.6e-16 60.1 0.0 5.4e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 CCL99652.1 - 4e-08 33.1 0.2 4e-08 33.1 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCL99652.1 - 0.0021 18.1 0.0 0.006 16.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 CCL99652.1 - 2.2 7.8 8.4 4.7 6.8 5.8 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type PALP PF00291.20 CCL99653.1 - 5.3e-39 134.2 0.1 3.5e-38 131.5 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CoA_binding_2 PF13380.1 CCL99654.1 - 1e-31 109.4 0.0 1.2e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 CCL99654.1 - 0.016 15.7 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain gp37_C PF12604.3 CCL99654.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Tail fiber protein gp37 C terminal Mito_carr PF00153.22 CCL99655.1 - 4.6e-65 215.3 4.9 1.7e-22 78.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NUDIX PF00293.23 CCL99656.1 - 1e-17 64.0 0.0 1.8e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 CCL99656.1 - 2.1e-10 40.7 0.0 8e-10 38.9 0.0 2.0 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 CCL99656.1 - 0.00025 20.4 0.2 0.00048 19.5 0.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 CCL99656.1 - 0.13 12.0 0.3 0.25 11.0 0.2 1.5 1 0 0 1 1 1 0 Nudix N-terminal NUDIX PF00293.23 CCL99657.1 - 1.6e-16 60.1 0.0 3.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 CCL99657.1 - 1.7e-07 31.4 0.3 6.3e-07 29.6 0.2 2.0 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 CCL99657.1 - 0.00012 21.5 2.3 0.00021 20.6 1.6 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 CCL99657.1 - 0.056 12.6 0.5 0.12 11.6 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF3827 PF12877.2 CCL99658.1 - 0.016 13.3 2.9 0.019 13.1 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF3844 PF12955.2 CCL99659.1 - 9.4e-31 105.9 4.3 1.4e-30 105.3 3.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 CCL99659.1 - 2.7 8.2 11.6 5.8 7.1 8.1 1.6 1 1 0 1 1 1 0 EGF-like domain Rubis-subs-bind PF09273.6 CCL99660.1 - 1.5e-12 47.5 0.3 2.5e-12 46.8 0.2 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 CCL99660.1 - 2.9e-10 40.6 0.0 1.8e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 SET domain CRAL_TRIO PF00650.15 CCL99661.1 - 1.4e-07 31.1 0.0 0.019 14.4 0.0 2.5 3 0 0 3 3 3 2 CRAL/TRIO domain MCM_N PF14551.1 CCL99661.1 - 0.11 13.0 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 MCM N-terminal domain Metallophos PF00149.23 CCL99662.1 - 2.6e-27 95.5 0.0 3.4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CTP_transf_2 PF01467.21 CCL99664.1 - 2.5e-05 24.3 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase 2Fe-2S_Ferredox PF11591.3 CCL99664.1 - 3.9 7.2 6.8 0.38 10.4 1.1 2.0 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide zf-C2H2_4 PF13894.1 CCL99665.1 - 0.00043 20.4 5.1 1.5 9.3 0.0 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCL99665.1 - 0.003 17.7 7.5 0.0082 16.4 0.0 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCL99665.1 - 0.034 14.4 1.3 0.45 10.9 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 CCL99665.1 - 1.2 8.9 5.6 21 4.9 0.2 3.3 2 1 0 2 2 2 0 zinc-finger of a C2HC-type OHCU_decarbox PF09349.5 CCL99666.1 - 1.7e-30 106.4 0.0 2.1e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DnaJ PF00226.26 CCL99667.1 - 4.1e-20 71.2 0.2 8e-20 70.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Fib_alpha PF08702.5 CCL99667.1 - 0.87 9.7 4.3 1.4 9.0 0.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.9 CCL99667.1 - 3.5 7.5 18.0 1.9e+02 1.8 12.5 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Bac_small_YrzI PF09501.5 CCL99667.1 - 3.6 7.5 7.7 1.1 9.2 0.6 2.4 1 1 1 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) BUD22 PF09073.5 CCL99668.1 - 0.87 8.5 6.6 2.8 6.9 4.6 1.8 1 0 0 1 1 1 0 BUD22 SH3_1 PF00018.23 CCL99670.1 - 7.5e-19 66.8 2.2 8e-09 34.7 0.1 3.1 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CCL99670.1 - 1.1e-14 53.7 1.5 1.9e-07 30.5 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CCL99670.1 - 8.5e-12 44.3 0.2 1.3e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.12 CCL99670.1 - 1.8e-11 43.6 0.0 3.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCL99670.1 - 2.3e-10 40.4 0.0 3.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 CCL99670.1 - 2.4e-10 40.7 0.0 4.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.6 CCL99670.1 - 0.0044 17.1 1.9 2.3 8.4 0.1 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain Dict-STAT-coil PF09267.5 CCL99670.1 - 0.073 13.2 0.3 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil DnaJ PF00226.26 CCL99671.1 - 3.8e-20 71.3 0.2 6.1e-20 70.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_C12 PF01088.16 CCL99672.1 - 9.8e-51 171.9 0.0 7e-49 165.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Merozoite_SPAM PF07133.6 CCL99673.1 - 2.1 8.2 27.2 3.9 7.3 18.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Cyto_heme_lyase PF01265.12 CCL99674.1 - 1.7e-71 240.8 0.1 2e-71 240.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Tim44 PF04280.10 CCL99675.1 - 8.5e-32 110.1 1.2 1.8e-31 109.1 0.4 1.9 2 0 0 2 2 2 1 Tim44-like domain Complex1_LYR_1 PF13232.1 CCL99675.1 - 0.009 16.2 2.5 0.025 14.7 1.1 2.3 2 0 0 2 2 2 1 Complex1_LYR-like Paralemmin PF03285.10 CCL99675.1 - 0.056 12.9 6.4 0.087 12.2 4.4 1.3 1 0 0 1 1 1 0 Paralemmin T2SF PF00482.18 CCL99675.1 - 0.44 10.4 3.2 0.5 10.2 0.7 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF3813 PF12758.2 CCL99675.1 - 5.9 7.1 6.1 2.1 8.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3813) WD40 PF00400.27 CCL99676.1 - 1.3e-15 56.5 5.0 0.00023 20.9 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCL99676.1 - 0.00031 19.6 0.2 0.00089 18.1 0.1 1.8 2 1 0 2 2 2 1 Nup133 N terminal like TMF_TATA_bd PF12325.3 CCL99676.1 - 0.052 13.2 0.5 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding WD40_alt PF14077.1 CCL99676.1 - 0.064 12.8 1.0 0.13 11.9 0.7 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif NADH-u_ox-rdase PF10785.4 CCL99677.1 - 3.9e-30 103.9 0.1 5.3e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 CCL99677.1 - 3.3e-14 52.3 0.0 4.4e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit zf-RanBP PF00641.13 CCL99678.1 - 4.4e-10 38.4 14.6 4.4e-06 25.6 2.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 CCL99678.1 - 0.036 13.6 1.9 6.6 6.3 0.1 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Prim_Zn_Ribbon PF08273.7 CCL99678.1 - 0.12 12.5 0.4 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-P11 PF03854.9 CCL99678.1 - 0.81 9.2 5.1 0.48 9.9 0.3 2.3 2 0 0 2 2 2 0 P-11 zinc finger Pkinase PF00069.20 CCL99679.1 - 4e-73 245.7 0.0 4.7e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99679.1 - 1.1e-31 109.8 0.0 3.7e-31 108.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCL99679.1 - 0.022 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CCL99679.1 - 0.033 13.1 0.0 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Chromo PF00385.19 CCL99680.1 - 2.2e-10 40.0 0.1 4.4e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain adh_short_C2 PF13561.1 CCL99681.1 - 6.8e-24 84.9 0.2 3.3e-22 79.4 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCL99681.1 - 2e-19 70.0 1.3 2.8e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCL99681.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CCL99681.1 - 0.033 13.8 0.7 0.07 12.7 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCL99681.1 - 0.043 13.8 0.2 0.22 11.5 0.1 2.1 1 1 1 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 CCL99681.1 - 0.063 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.8 CCL99681.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family adh_short_C2 PF13561.1 CCL99682.1 - 1.5e-20 74.0 0.0 1.1e-18 67.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCL99682.1 - 9.8e-18 64.6 1.1 1.3e-15 57.7 0.8 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCL99682.1 - 1.9e-05 24.4 0.1 4.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 KR domain CbiD PF01888.12 CCL99682.1 - 0.038 12.9 0.1 0.078 11.9 0.1 1.4 1 0 0 1 1 1 0 CbiD Pro-kuma_activ PF09286.6 CCL99683.1 - 2.9e-37 127.8 0.0 4.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCL99683.1 - 6.7e-10 38.5 2.1 1.4e-09 37.5 1.4 1.6 1 0 0 1 1 1 1 Subtilase family FF PF01846.14 CCL99684.1 - 6.1e-33 112.5 5.9 8.9e-11 41.5 0.0 5.9 5 1 1 6 6 6 4 FF domain WW PF00397.21 CCL99684.1 - 5.2e-13 48.5 15.1 3.4e-07 30.0 1.1 2.8 2 0 0 2 2 2 2 WW domain TarH PF02203.10 CCL99684.1 - 0.82 9.4 5.5 0.37 10.6 0.1 2.7 3 0 0 3 3 3 0 Tar ligand binding domain homologue Ribosomal_L21p PF00829.16 CCL99685.1 - 2.2e-16 59.7 0.3 2.7e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein ATP-synt_ab PF00006.20 CCL99686.1 - 2.8e-70 236.1 0.0 3.9e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCL99686.1 - 2.1e-22 79.7 0.1 5.6e-22 78.3 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCL99686.1 - 6.1e-18 64.8 1.0 1.5e-17 63.5 0.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CCL99686.1 - 0.00033 20.5 0.3 0.00093 19.0 0.1 1.9 2 1 0 2 2 2 1 HAS barrel domain FliD_C PF07195.7 CCL99687.1 - 0.074 12.3 0.1 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Spc7_N PF15402.1 CCL99687.1 - 0.11 10.4 0.8 0.16 9.9 0.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 MFS_1 PF07690.11 CCL99688.1 - 1.1e-46 159.2 43.1 1.1e-46 159.2 29.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCL99688.1 - 8e-10 37.8 11.4 3.9e-09 35.6 1.5 3.6 2 2 1 3 3 3 2 Sugar (and other) transporter GST_C_3 PF14497.1 CCL99688.1 - 0.075 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BatA PF07584.6 CCL99688.1 - 8.8 6.5 7.8 2.9 8.1 0.3 2.9 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal DUF2408 PF10303.4 CCL99689.1 - 8.9e-53 177.9 0.1 6.7e-20 71.5 0.0 5.7 4 2 1 5 5 5 5 Protein of unknown function (DUF2408) MscS_porin PF12795.2 CCL99689.1 - 0.46 9.7 6.5 6 6.1 0.0 3.3 4 0 0 4 4 4 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.7 CCL99689.1 - 0.8 9.5 4.0 2.4 7.9 0.5 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 CCL99690.1 - 1.2e-41 141.8 32.7 1.8e-28 99.2 13.2 2.1 2 0 0 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 CCL99690.1 - 4e-13 49.0 31.1 2.2e-05 23.6 3.2 3.1 2 1 1 3 3 3 3 Tropomyosin AAA_27 PF13514.1 CCL99690.1 - 0.0021 15.8 24.6 0.0034 15.1 17.0 1.2 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.4 CCL99690.1 - 0.0046 16.8 28.7 0.0058 16.4 3.1 2.6 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4600 PF15372.1 CCL99690.1 - 0.019 15.2 8.5 0.019 15.2 5.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Uds1 PF15456.1 CCL99690.1 - 0.043 13.7 20.4 0.1 12.5 3.5 2.8 1 1 2 3 3 3 0 Up-regulated During Septation GAS PF13851.1 CCL99690.1 - 0.069 12.3 28.5 0.18 11.0 10.7 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 CCL99690.1 - 0.08 12.4 31.9 0.036 13.6 4.7 2.9 1 1 1 3 3 3 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.3 CCL99690.1 - 0.093 12.4 22.6 0.31 10.7 1.7 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.7 CCL99690.1 - 0.13 11.9 16.6 1.3 8.7 0.4 3.1 1 1 3 4 4 4 0 Laminin Domain II WEMBL PF05701.6 CCL99690.1 - 0.18 10.2 28.1 0.78 8.1 19.5 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Sec2p PF06428.6 CCL99690.1 - 0.21 11.4 24.4 0.05 13.4 6.5 3.2 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p TMF_DNA_bd PF12329.3 CCL99690.1 - 0.29 10.9 25.9 2.9 7.7 0.8 3.6 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF869 PF05911.6 CCL99690.1 - 0.4 8.8 22.9 0.031 12.5 5.2 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) ADIP PF11559.3 CCL99690.1 - 0.42 10.5 23.9 0.38 10.6 1.7 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding NAD_binding_4 PF07993.7 CCL99690.1 - 0.51 9.2 8.5 12 4.6 5.9 2.2 1 1 0 1 1 1 0 Male sterility protein TACC PF05010.9 CCL99690.1 - 0.79 9.4 19.6 3.7 7.2 6.5 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) DUF3584 PF12128.3 CCL99690.1 - 0.93 6.7 27.6 1.4 6.1 10.9 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) SlyX PF04102.7 CCL99690.1 - 1 9.7 21.8 0.14 12.5 2.2 4.0 2 1 2 4 4 4 0 SlyX DUF3359 PF11839.3 CCL99690.1 - 1.1 9.6 14.2 1.2 9.5 1.4 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF3359) Fib_alpha PF08702.5 CCL99690.1 - 1.1 9.3 13.4 1.5 8.9 0.4 2.9 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BRE1 PF08647.6 CCL99690.1 - 1.5 8.8 22.9 1.8 8.5 1.4 3.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase IncA PF04156.9 CCL99690.1 - 1.5 8.3 26.0 1 8.9 3.0 2.5 1 1 0 2 2 2 0 IncA protein Seryl_tRNA_N PF02403.17 CCL99690.1 - 1.9 8.5 24.6 2.7 8.0 10.3 2.6 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Cluap1 PF10234.4 CCL99690.1 - 2 7.5 20.4 7.4 5.6 6.7 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF4463 PF14703.1 CCL99690.1 - 2 8.9 17.1 0.96 10.0 1.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) FliD_C PF07195.7 CCL99690.1 - 2.1 7.5 13.8 33 3.6 9.0 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus PspA_IM30 PF04012.7 CCL99690.1 - 2.1 7.6 27.6 0.15 11.3 9.5 2.3 1 1 1 2 2 2 0 PspA/IM30 family Mod_r PF07200.8 CCL99690.1 - 2.1 8.2 23.4 2.6 7.9 3.0 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.3 CCL99690.1 - 2.3 7.4 24.6 3.9 6.6 1.6 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) GBP_C PF02841.9 CCL99690.1 - 3.1 6.8 23.6 0.54 9.3 7.8 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Z1 PF10593.4 CCL99690.1 - 4.1 6.5 6.9 0.72 9.0 0.4 2.1 2 0 0 2 2 2 0 Z1 domain Rab5-bind PF09311.6 CCL99690.1 - 4.9 6.9 24.8 0.12 12.2 3.4 2.4 2 1 0 2 2 2 0 Rabaptin-like protein PilJ PF13675.1 CCL99690.1 - 5.6 7.3 16.4 0.31 11.3 1.2 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Nup54 PF13874.1 CCL99690.1 - 6.5 6.4 18.9 2.9 7.5 5.3 2.5 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF3391 PF11871.3 CCL99690.1 - 6.6 6.9 14.3 5.7 7.1 1.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) HisKA_3 PF07730.8 CCL99690.1 - 6.7 7.1 14.2 6.1 7.2 0.3 3.8 2 1 1 3 3 3 0 Histidine kinase DUF3287 PF11690.3 CCL99690.1 - 8.2 6.5 9.8 1.2 9.2 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) OmpH PF03938.9 CCL99690.1 - 8.3 6.3 26.8 9.4 6.1 11.5 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ax_dynein_light PF10211.4 CCL99690.1 - 9 6.0 23.1 1.1 9.0 2.3 2.5 2 1 1 3 3 3 0 Axonemal dynein light chain BLOC1_2 PF10046.4 CCL99690.1 - 9.3 6.4 17.6 4 7.6 3.0 3.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SelR PF01641.13 CCL99691.1 - 2e-44 150.2 0.0 2.4e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.1 CCL99691.1 - 0.0055 16.5 0.6 0.077 12.8 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 GFA PF04828.9 CCL99691.1 - 0.011 15.6 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.9 CCL99691.1 - 0.043 13.8 0.4 0.26 11.3 0.3 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.1 CCL99691.1 - 0.049 12.8 1.6 4.9 6.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF678 PF05077.7 CCL99691.1 - 0.14 12.2 0.1 6.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DZR PF12773.2 CCL99691.1 - 0.15 11.9 1.2 0.85 9.4 0.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 CCL99691.1 - 0.19 11.0 5.4 7.5 5.9 0.1 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 CCL99691.1 - 0.36 10.3 3.1 1.2 8.7 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DnaJ_CXXCXGXG PF00684.14 CCL99691.1 - 0.48 10.5 3.3 1.1 9.3 0.1 2.4 2 1 0 2 2 2 0 DnaJ central domain Glyco_hydro_3 PF00933.16 CCL99692.1 - 7.6e-59 199.1 0.0 1.2e-58 198.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCL99692.1 - 3.8e-41 141.0 0.0 5.5e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCL99692.1 - 9.8e-08 31.8 0.0 2.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_membrane PF00664.18 CCL99693.1 - 2.3e-56 191.2 37.6 7.3e-31 107.5 5.9 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCL99693.1 - 5.2e-39 133.6 0.0 8.8e-19 68.1 0.0 3.3 2 1 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 CCL99693.1 - 0.0001 21.7 0.8 0.051 13.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 CCL99693.1 - 0.00011 21.5 0.2 1.3 8.2 0.0 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 CCL99693.1 - 0.00012 22.0 1.8 0.34 10.8 0.1 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase Miro PF08477.8 CCL99693.1 - 0.00019 21.9 2.3 0.36 11.3 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 CCL99693.1 - 0.00048 19.1 0.0 0.046 12.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CCL99693.1 - 0.00056 19.4 0.2 0.13 11.7 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_16 PF13191.1 CCL99693.1 - 0.00075 19.5 0.1 1.1 9.1 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_23 PF13476.1 CCL99693.1 - 0.00076 19.8 0.1 0.98 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CCL99693.1 - 0.00078 19.3 3.8 0.12 12.2 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 CCL99693.1 - 0.00092 18.6 0.4 0.52 9.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CCL99693.1 - 0.0012 18.5 0.0 0.59 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCL99693.1 - 0.0019 17.4 0.1 0.63 9.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 CCL99693.1 - 0.0023 16.7 0.1 1.9 7.2 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 CCL99693.1 - 0.0044 17.1 0.1 0.21 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CCL99693.1 - 0.0088 16.0 0.6 1.9 8.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 CCL99693.1 - 0.0097 16.2 0.1 2.4 8.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCL99693.1 - 0.0097 15.0 0.7 3.5 6.6 0.1 3.2 3 0 0 3 3 3 1 Zeta toxin MobB PF03205.9 CCL99693.1 - 0.028 14.1 0.4 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CCL99693.1 - 0.033 13.6 3.9 0.9 8.9 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 CCL99693.1 - 0.034 13.6 1.2 2 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 CCL99693.1 - 0.052 13.3 1.4 1.4 8.7 0.2 2.4 2 0 0 2 2 2 0 Dynamin family AAA_17 PF13207.1 CCL99693.1 - 0.06 14.1 1.6 2.1 9.1 0.7 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CCL99693.1 - 0.068 12.8 1.0 7.5 6.2 0.1 2.8 2 0 0 2 2 2 0 NTPase GTP_EFTU PF00009.22 CCL99693.1 - 0.12 11.7 0.2 5 6.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 CCL99693.1 - 0.14 12.0 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CCL99693.1 - 0.15 10.6 0.4 3.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 CCL99693.1 - 0.15 12.2 0.4 22 5.2 0.0 3.1 3 1 0 3 3 2 0 RNA helicase NB-ARC PF00931.17 CCL99693.1 - 0.2 10.4 0.9 12 4.6 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Arch_ATPase PF01637.13 CCL99693.1 - 0.22 11.1 1.9 4.8 6.8 0.1 2.6 2 1 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 CCL99693.1 - 0.25 10.9 0.9 13 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CCL99693.1 - 0.34 10.4 1.5 2.2 7.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RdRP_3 PF00998.18 CCL99693.1 - 0.44 8.9 0.0 2.9 6.2 0.0 1.9 2 0 0 2 2 2 0 Viral RNA dependent RNA polymerase UPF0079 PF02367.12 CCL99693.1 - 0.57 9.8 3.2 0.26 10.9 0.4 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CCL99693.1 - 1.1 8.9 4.9 20 4.8 0.2 3.3 3 0 0 3 3 3 0 NACHT domain Epimerase PF01370.16 CCL99694.1 - 3.1e-25 88.9 0.0 4.5e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCL99694.1 - 4.7e-18 64.8 0.0 7.2e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCL99694.1 - 3.7e-15 56.3 0.2 5.9e-15 55.7 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCL99694.1 - 1e-09 37.7 0.2 3e-09 36.1 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CCL99694.1 - 5.7e-07 29.0 0.1 1.1e-06 28.1 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 CCL99694.1 - 2.1e-06 26.8 0.1 3.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CCL99694.1 - 1.4e-05 25.0 0.1 0.00011 22.1 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 CCL99694.1 - 0.00099 19.0 0.2 0.002 18.0 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 CCL99694.1 - 0.0032 17.1 0.1 0.04 13.5 0.0 2.2 1 1 0 1 1 1 1 KR domain DUF2150 PF09920.4 CCL99694.1 - 0.034 13.7 0.1 5.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) DUF2280 PF10045.4 CCL99694.1 - 0.18 11.7 0.5 1 9.2 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Peptidase_S9 PF00326.16 CCL99695.1 - 2.2e-34 118.5 0.0 3.3e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCL99695.1 - 9.9e-13 48.0 0.0 2.7e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCL99695.1 - 1.9e-07 31.1 1.5 4.8e-07 29.8 0.3 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 CCL99695.1 - 3.4e-06 26.6 0.7 0.0087 15.7 0.4 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat LIP PF03583.9 CCL99695.1 - 0.00024 20.4 0.0 0.0092 15.2 0.0 2.9 3 0 0 3 3 3 1 Secretory lipase Abhydrolase_2 PF02230.11 CCL99695.1 - 0.00045 19.7 0.0 0.075 12.4 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 CCL99695.1 - 0.0031 17.0 0.0 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 CCL99695.1 - 0.0043 16.3 0.2 0.016 14.4 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 CCL99695.1 - 0.16 10.4 0.0 8.7 4.7 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Nup35_RRM PF05172.8 CCL99696.1 - 7.2e-09 35.3 0.0 2.2e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CCL99696.1 - 6.5e-06 25.8 0.0 1.9e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif TPR_12 PF13424.1 CCL99697.1 - 6.1e-09 35.6 1.2 1.8 8.5 0.0 7.3 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCL99697.1 - 0.025 15.2 1.4 14 6.5 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Lipoprotein_20 PF13942.1 CCL99697.1 - 0.12 11.9 0.1 15 5.0 0.0 3.4 2 1 1 4 4 4 0 YfhG lipoprotein Peptidase_C14 PF00656.17 CCL99698.1 - 2e-12 47.3 0.0 2.9e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Pkinase PF00069.20 CCL99699.1 - 1e-11 44.4 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99699.1 - 4.9e-07 29.0 0.1 9.9e-06 24.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCL99699.1 - 0.0004 20.1 0.1 0.0043 16.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCL99699.1 - 0.00053 19.1 0.0 0.0009 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CCL99699.1 - 0.0084 15.6 0.0 0.045 13.3 0.0 2.1 3 0 0 3 3 3 1 Choline/ethanolamine kinase RIO1 PF01163.17 CCL99699.1 - 0.05 12.9 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Fis1_TPR_N PF14852.1 CCL99700.1 - 4.4e-05 22.6 1.6 2.1 7.7 0.0 4.4 4 0 0 4 4 4 3 Fis1 N-terminal tetratricopeptide repeat PTB PF08416.8 CCL99700.1 - 0.016 15.1 2.6 1.1 9.1 0.0 3.2 3 0 0 3 3 3 0 Phosphotyrosine-binding domain TPR_10 PF13374.1 CCL99701.1 - 2.7e-05 23.9 0.0 0.85 9.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCL99701.1 - 4.3e-05 23.0 0.0 0.44 10.2 0.0 4.3 2 1 2 4 4 4 2 TPR repeat Fis1_TPR_N PF14852.1 CCL99701.1 - 0.00075 18.7 0.6 10 5.5 0.0 4.7 5 0 0 5 5 5 1 Fis1 N-terminal tetratricopeptide repeat TPR_17 PF13431.1 CCL99701.1 - 0.0017 18.3 0.2 0.095 12.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Syntaxin-6_N PF09177.6 CCL99701.1 - 0.011 16.1 0.3 2.5 8.5 0.0 3.3 2 1 2 4 4 4 0 Syntaxin 6, N-terminal DUF2457 PF10446.4 CCL99701.1 - 0.012 14.4 0.4 0.018 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cation_ATPase_C PF00689.16 CCL99702.1 - 0.21 11.0 11.5 0.014 14.9 3.5 2.0 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus 4HBT PF03061.17 CCL99703.1 - 1.7e-14 53.6 0.4 2.3e-14 53.2 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 CCL99703.1 - 0.0012 18.6 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 CCL99703.1 - 0.0051 16.7 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) DER1 PF04511.10 CCL99704.1 - 2e-46 158.0 4.3 2.3e-46 157.7 3.0 1.0 1 0 0 1 1 1 1 Der1-like family DUF4436 PF14494.1 CCL99705.1 - 0.0001 21.7 0.1 0.00017 21.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Flavi_M PF01004.14 CCL99705.1 - 3.9 6.9 5.0 15 5.0 1.4 2.3 1 1 1 2 2 2 0 Flavivirus envelope glycoprotein M SET PF00856.23 CCL99706.1 - 1.4e-08 35.1 0.0 2.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 SET domain DUF373 PF04123.8 CCL99706.1 - 0.53 9.2 2.8 0.7 8.8 0.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF4504 PF14953.1 CCL99707.1 - 0.024 13.9 0.0 0.029 13.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4504) Pro_isomerase PF00160.16 CCL99708.1 - 6.3e-47 159.6 0.0 1.2e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CCL99708.1 - 2.7e-11 42.8 1.7 3e-06 26.8 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Mrr_N PF14338.1 CCL99709.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Mrr N-terminal domain His_Phos_1 PF00300.17 CCL99710.1 - 1e-29 103.6 0.0 1.6e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ufd2P_core PF10408.4 CCL99711.1 - 3.4e-194 646.6 0.0 4e-194 646.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CCL99711.1 - 9.4e-28 95.9 0.4 2.9e-27 94.4 0.2 1.9 1 0 0 1 1 1 1 U-box domain Eaf7 PF07904.8 CCL99712.1 - 2.3e-16 59.5 0.0 3.6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Ribosomal_L22 PF00237.14 CCL99713.1 - 7.1e-31 106.2 0.6 8.9e-31 105.9 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Asp_Glu_race_2 PF14669.1 CCL99713.1 - 0.058 12.7 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative aspartate racemase Oxidored_FMN PF00724.15 CCL99714.1 - 4.9e-72 242.7 0.0 6.2e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF221 PF02714.10 CCL99716.1 - 1.3e-39 135.9 21.0 3.8e-30 104.8 5.8 2.2 1 1 1 2 2 2 2 Domain of unknown function DUF221 DUF4463 PF14703.1 CCL99716.1 - 9.8e-05 22.7 0.0 0.00099 19.5 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 CCL99716.1 - 0.0011 18.8 0.1 0.025 14.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL99716.1 - 0.033 14.0 0.0 0.13 12.1 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCL99716.1 - 0.062 12.9 0.4 4.2 7.0 0.1 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3779 PF12621.3 CCL99716.1 - 0.14 12.1 0.9 0.31 10.9 0.6 1.6 1 0 0 1 1 1 0 Phosphate metabolism protein ETC_C1_NDUFA4 PF04800.7 CCL99717.1 - 4.2e-36 122.8 0.1 5.5e-36 122.4 0.1 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF3892 PF13031.1 CCL99717.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) RICTOR_N PF14664.1 CCL99718.1 - 6.2e-93 311.3 1.1 8.8e-93 310.8 0.2 1.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 CCL99718.1 - 1.4e-80 269.5 1.9 3.3e-79 265.0 0.6 3.5 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 CCL99718.1 - 2.4e-30 104.8 0.1 1e-29 102.8 0.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CCL99718.1 - 4.7e-29 100.1 0.0 1.1e-26 92.5 0.0 4.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 CCL99718.1 - 0.00017 21.2 5.8 0.00041 20.0 4.0 1.7 1 0 0 1 1 1 1 Hr1 repeat CgtA PF06306.6 CCL99718.1 - 0.083 12.0 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) Desmo_N PF06771.6 CCL99718.1 - 0.25 11.3 2.3 1.1 9.2 0.3 2.9 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus Peptidase_M20 PF01546.23 CCL99719.1 - 4.6e-23 81.7 0.0 1.1e-22 80.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCL99719.1 - 2.2e-12 46.6 0.0 1.1e-11 44.4 0.0 2.2 2 1 0 2 2 2 1 Peptidase dimerisation domain Mod_r PF07200.8 CCL99720.1 - 2.8e-19 69.4 6.2 1.1e-18 67.6 4.3 1.7 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF2051 PF09738.4 CCL99720.1 - 0.0049 16.2 0.2 0.007 15.6 0.1 1.2 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) Syntaxin_2 PF14523.1 CCL99720.1 - 0.18 11.8 0.9 0.32 11.0 0.3 1.6 2 0 0 2 2 2 0 Syntaxin-like protein IncA PF04156.9 CCL99720.1 - 3.1 7.3 5.0 5.5 6.5 3.1 1.7 1 1 1 2 2 2 0 IncA protein Sod_Cu PF00080.15 CCL99721.1 - 8.1e-45 152.4 1.0 1e-44 152.1 0.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) tRNA_int_end_N2 PF12928.2 CCL99722.1 - 7.9e-22 76.5 0.0 1.3e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 CCL99722.1 - 0.0086 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Mito_carr PF00153.22 CCL99723.1 - 1.8e-58 194.2 5.3 5.2e-21 74.1 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Hist_deacetyl PF00850.14 CCL99724.1 - 3.7e-55 187.4 0.9 4.5e-55 187.1 0.6 1.1 1 0 0 1 1 1 1 Histone deacetylase domain zf-rbx1 PF12678.2 CCL99725.1 - 3.1e-07 30.3 5.1 8.1e-07 29.0 3.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCL99725.1 - 4.1e-06 26.5 12.9 5.3e-05 22.9 7.9 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCL99725.1 - 0.0037 16.9 5.6 0.0041 16.7 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCL99725.1 - 0.046 13.3 6.9 0.12 12.0 3.9 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCL99725.1 - 0.4 10.5 5.5 3.4 7.5 3.7 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CCL99725.1 - 0.46 10.5 12.3 0.026 14.5 3.7 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 CCL99725.1 - 2 8.5 7.8 0.075 13.0 0.7 2.1 3 0 0 3 3 3 0 RING-variant domain zf-RING_5 PF14634.1 CCL99725.1 - 2.4 7.9 7.6 5.7 6.7 4.3 2.1 1 1 1 2 2 2 0 zinc-RING finger domain BSP_II PF05432.6 CCL99725.1 - 4.2 6.5 14.9 0.49 9.6 5.9 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Amidohydro_1 PF01979.15 CCL99726.1 - 6.7e-29 101.5 0.0 6.6e-28 98.3 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CCL99726.1 - 2.1e-25 90.2 0.1 4.7e-24 85.8 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 CCL99726.1 - 6.8e-11 41.8 0.3 1.7e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CCL99726.1 - 8.2e-07 28.5 0.0 0.0025 17.0 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family vMSA PF00695.14 CCL99727.1 - 0.97 8.5 2.9 1.5 7.9 2.0 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Histone PF00125.19 CCL99728.1 - 4.1e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCL99728.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCL99728.1 - 0.00083 19.3 1.2 0.0014 18.6 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCL99728.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 CCL99728.1 - 0.16 11.1 1.7 0.18 11.0 1.2 1.2 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DAO PF01266.19 CCL99729.1 - 2.5e-49 168.0 0.1 3.4e-49 167.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CCL99729.1 - 6.1e-07 28.8 0.2 1.3e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCL99729.1 - 1.5e-06 27.3 4.7 1.1e-05 24.5 3.2 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCL99729.1 - 0.00046 20.1 0.2 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCL99729.1 - 0.0031 17.5 0.6 0.011 15.7 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 CCL99729.1 - 0.0059 16.2 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 CCL99729.1 - 0.0089 14.9 0.2 0.047 12.5 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 CCL99729.1 - 0.0091 16.3 0.2 0.024 15.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCL99729.1 - 0.02 13.9 1.2 0.16 10.9 0.8 2.1 1 1 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 CCL99729.1 - 0.022 13.7 0.4 0.29 10.0 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 CCL99729.1 - 0.033 12.6 0.7 0.05 12.0 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 CCL99729.1 - 0.039 13.0 0.8 0.059 12.4 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 CCL99729.1 - 0.093 12.7 0.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RhoGAP PF00620.22 CCL99730.1 - 1.9e-33 115.2 0.0 3.1e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 CCL99730.1 - 2.5e-32 111.8 0.7 3.7e-32 111.2 0.1 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CCL99730.1 - 4.1e-05 23.1 0.2 0.00012 21.6 0.1 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain bZIP_2 PF07716.10 CCL99731.1 - 3.5e-07 29.9 12.8 6.6e-07 29.0 8.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CCL99731.1 - 5e-07 29.5 7.7 9.1e-07 28.7 5.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 CCL99731.1 - 0.0099 16.1 4.7 0.018 15.2 3.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2839 PF10999.3 CCL99731.1 - 3.4 7.7 4.4 7.1 6.7 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) GST_N PF02798.15 CCL99732.1 - 2e-18 66.2 0.0 3.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCL99732.1 - 6.5e-15 54.8 0.0 1.4e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCL99732.1 - 6e-12 45.6 0.0 9.7e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCL99732.1 - 1.1e-10 41.3 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCL99732.1 - 5.8e-07 29.3 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCL99732.1 - 1.9e-05 25.0 0.1 2.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Toxin_59 PF15537.1 CCL99732.1 - 0.12 12.4 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative toxin 59 F-box-like PF12937.2 CCL99733.1 - 1.4e-05 24.6 0.6 3.4e-05 23.4 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCL99733.1 - 0.02 14.5 0.1 0.097 12.3 0.0 2.1 2 0 0 2 2 2 0 F-box domain TAF PF02969.12 CCL99734.1 - 6.7e-22 77.2 0.5 1.3e-21 76.2 0.3 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 CCL99734.1 - 1.4e-16 60.4 0.1 3.4e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 CCL99734.1 - 1.6e-06 28.1 1.2 7e-06 26.0 0.7 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 CCL99734.1 - 0.013 15.1 0.1 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated CENP-S PF15630.1 CCL99734.1 - 0.05 13.7 0.2 0.098 12.8 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCL99734.1 - 0.066 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HEAT_EZ PF13513.1 CCL99734.1 - 0.35 11.4 2.9 36 5.0 0.1 3.9 2 2 2 4 4 4 0 HEAT-like repeat FMN_dh PF01070.13 CCL99735.1 - 7e-115 383.6 0.0 8.8e-115 383.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCL99735.1 - 4.8e-22 77.5 0.0 9.5e-22 76.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 CCL99735.1 - 0.0013 17.9 0.1 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 CCL99735.1 - 0.0014 17.6 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CCL99735.1 - 0.004 16.0 0.0 0.0078 15.1 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Oxidored_molyb PF00174.14 CCL99737.1 - 5.9e-48 162.4 0.0 1.4e-46 158.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CCL99737.1 - 6.7e-23 80.7 1.9 1.1e-22 80.0 1.3 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain IBN_N PF03810.14 CCL99738.1 - 2.8e-10 39.9 0.0 3.5e-07 30.0 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CCL99738.1 - 4.9e-06 26.7 0.5 0.017 15.4 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.15 CCL99738.1 - 0.0019 16.6 0.7 0.24 9.6 0.2 2.5 2 0 0 2 2 2 2 Adaptin N terminal region Cnd3 PF12719.2 CCL99738.1 - 0.0024 16.9 0.9 0.0049 15.9 0.2 1.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Vac14_Fab1_bd PF12755.2 CCL99738.1 - 0.0034 17.7 0.0 0.38 11.1 0.0 3.7 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region Cse1 PF08506.5 CCL99738.1 - 0.0075 14.8 0.0 0.022 13.3 0.0 1.8 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 CCL99738.1 - 0.012 15.4 5.2 0.025 14.4 0.0 4.0 4 1 0 4 4 4 0 Exportin 1-like protein Nop14 PF04147.7 CCL99738.1 - 0.16 9.8 2.0 0.31 8.9 1.4 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2407_C PF13373.1 CCL99739.1 - 2.1e-17 63.3 2.8 5.6e-16 58.7 2.0 2.5 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 CCL99739.1 - 1.5e-15 57.0 0.1 2.9e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 CCL99739.1 - 3.2e-05 23.2 0.0 6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCL99739.1 - 0.0094 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IR1-M PF12185.3 CCL99739.1 - 0.068 12.8 0.9 0.32 10.7 0.3 2.2 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Kin17_mid PF10357.4 CCL99740.1 - 2.5e-48 162.9 0.9 4.1e-48 162.1 0.7 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 CCL99740.1 - 0.00025 21.1 6.1 0.0006 19.9 4.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCL99740.1 - 0.014 15.5 5.2 0.014 15.5 3.6 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCL99740.1 - 0.019 15.0 0.9 0.019 15.0 0.6 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) OmpH PF03938.9 CCL99740.1 - 0.097 12.6 0.4 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Actin PF00022.14 CCL99741.1 - 1.1e-65 221.5 0.0 1.3e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Actin NRDE PF05742.7 CCL99742.1 - 5.5e-32 111.1 0.0 9.8e-32 110.3 0.0 1.4 1 1 0 1 1 1 1 NRDE protein Zn_clus PF00172.13 CCL99743.1 - 1.3e-08 34.5 7.3 2.6e-08 33.6 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSS PF03034.10 CCL99744.1 - 1.1e-99 333.4 10.8 1.4e-99 333.0 7.5 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase zf-RING_2 PF13639.1 CCL99745.1 - 6e-12 45.1 14.1 1.4e-07 31.2 4.3 3.3 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 CCL99745.1 - 9.2e-05 22.0 10.7 0.012 15.3 1.4 3.3 3 0 0 3 3 3 2 zinc-RING finger domain zf-rbx1 PF12678.2 CCL99745.1 - 0.00011 22.2 4.1 0.00011 22.2 2.9 3.1 3 1 0 3 3 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCL99745.1 - 0.00077 19.0 12.4 0.0064 16.1 3.4 3.1 2 2 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCL99745.1 - 0.001 18.7 9.1 0.0064 16.1 0.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCL99745.1 - 0.0015 18.5 3.9 0.0015 18.5 2.7 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCL99745.1 - 0.0056 16.4 0.7 0.0056 16.4 0.5 3.1 3 1 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CCL99745.1 - 0.06 13.3 5.1 2.3 8.2 0.4 3.0 3 0 0 3 3 3 0 FANCL C-terminal domain Zip PF02535.17 CCL99745.1 - 0.14 11.1 6.2 0.24 10.3 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter zf-RING_UBOX PF13445.1 CCL99745.1 - 0.29 10.8 3.5 0.32 10.7 0.9 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCL99745.1 - 6.7 6.6 13.8 0.24 11.3 0.9 3.4 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Nop PF01798.13 CCL99748.1 - 2.9e-56 188.9 0.0 2.9e-56 188.9 0.0 1.7 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CCL99748.1 - 1e-25 89.2 0.1 2.1e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCL99748.1 - 2.7e-22 78.6 0.4 1.2e-21 76.5 0.3 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Na_H_Exchanger PF00999.16 CCL99749.1 - 3.2e-60 203.6 51.3 4.5e-60 203.1 35.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GDA1_CD39 PF01150.12 CCL99750.1 - 1.7e-88 297.0 0.0 2.2e-88 296.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family p450 PF00067.17 CCL99751.1 - 3.9e-66 223.4 0.0 2.5e-65 220.7 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.17 CCL99752.1 - 1.3e-47 162.8 0.0 1.5e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 CCL99753.1 - 3.2e-17 62.9 0.1 4.5e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCL99753.1 - 5.4e-06 26.1 0.0 6.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCL99753.1 - 2e-05 24.6 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCL99753.1 - 5.4e-05 22.7 0.0 0.00017 21.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCL99753.1 - 0.076 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCL99754.1 - 2.7e-28 98.9 0.3 3.5e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCL99754.1 - 2.3e-07 30.6 0.2 9.5e-06 25.3 0.0 2.3 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CCL99754.1 - 0.0001 21.8 0.0 0.013 14.9 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCL99754.1 - 0.0011 18.9 0.0 0.013 15.5 0.0 2.6 3 1 0 3 3 3 1 NADH(P)-binding DUF1776 PF08643.5 CCL99754.1 - 0.014 14.5 0.0 4.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) KdpC PF02669.10 CCL99754.1 - 0.031 13.9 0.5 1.5 8.4 0.0 2.4 2 1 1 3 3 3 0 K+-transporting ATPase, c chain NAD_binding_4 PF07993.7 CCL99754.1 - 0.075 11.9 0.0 1.4 7.8 0.0 2.9 2 1 0 2 2 2 0 Male sterility protein F-box-like PF12937.2 CCL99756.1 - 1.5e-06 27.8 1.7 5.9e-06 25.9 0.8 2.5 2 0 0 2 2 2 1 F-box-like DNA_ligase_ZBD PF03119.11 CCL99756.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain FAD_binding_3 PF01494.14 CCL99757.1 - 1.4e-76 257.9 0.0 1.8e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCL99757.1 - 1.6e-05 24.0 0.3 0.0011 17.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CCL99757.1 - 3.2e-05 23.1 0.1 5.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 CCL99757.1 - 5.2e-05 23.5 0.4 0.025 14.9 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCL99757.1 - 0.00016 21.5 0.2 0.003 17.4 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCL99757.1 - 0.00025 20.0 0.4 0.00062 18.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 CCL99757.1 - 0.00076 18.0 1.3 0.0064 15.0 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 CCL99757.1 - 0.00076 19.4 0.1 0.0023 17.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCL99757.1 - 0.0012 18.9 0.2 0.005 16.9 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCL99757.1 - 0.01 14.9 0.2 0.47 9.4 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 CCL99757.1 - 0.015 14.7 0.1 0.042 13.2 0.1 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1144 PF06610.8 CCL99757.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1144) NAD_binding_9 PF13454.1 CCL99757.1 - 0.027 14.2 0.6 0.12 12.1 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CCL99757.1 - 0.063 12.1 1.0 0.086 11.7 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein AAA PF00004.24 CCL99759.1 - 2.8e-79 263.7 0.0 2e-41 141.2 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCL99759.1 - 6.4e-12 45.8 1.4 2.1e-05 24.5 0.2 3.9 3 1 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.7 CCL99759.1 - 4.8e-10 38.8 0.0 0.00065 18.8 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCL99759.1 - 7.4e-10 38.6 0.2 2e-05 24.3 0.0 3.6 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCL99759.1 - 1.7e-08 34.1 2.0 4e-05 23.2 0.1 4.2 4 0 0 4 4 3 1 Part of AAA domain AAA_22 PF13401.1 CCL99759.1 - 6.8e-08 32.7 0.0 0.0011 19.1 0.0 3.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCL99759.1 - 2.1e-07 30.9 0.0 5.5e-05 23.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCL99759.1 - 2.1e-07 30.5 0.1 6.7e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 CCL99759.1 - 6.3e-07 28.9 0.3 0.1 12.0 0.1 3.5 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CCL99759.1 - 8.7e-07 28.2 0.0 0.00034 19.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 CCL99759.1 - 1.7e-05 25.6 0.0 0.00085 20.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CCL99759.1 - 4e-05 23.5 0.0 0.0019 18.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CCL99759.1 - 6e-05 21.9 0.2 0.03 13.0 0.0 2.6 3 0 0 3 3 3 1 TIP49 C-terminus AAA_11 PF13086.1 CCL99759.1 - 0.00016 21.3 0.0 0.003 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCL99759.1 - 0.00023 21.3 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 CCL99759.1 - 0.00034 20.6 0.0 0.06 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCL99759.1 - 0.00065 18.9 0.3 0.28 10.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCL99759.1 - 0.00081 19.2 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 CCL99759.1 - 0.0013 18.4 0.0 0.62 9.6 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein NACHT PF05729.7 CCL99759.1 - 0.0025 17.4 0.1 0.094 12.3 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 CCL99759.1 - 0.0031 17.1 0.1 2.2 7.8 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CCL99759.1 - 0.0033 17.4 0.0 0.43 10.6 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain DAP3 PF10236.4 CCL99759.1 - 0.0056 15.6 0.0 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 UPF0079 PF02367.12 CCL99759.1 - 0.0075 15.8 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CCL99759.1 - 0.0094 15.2 0.1 0.089 12.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 CCL99759.1 - 0.018 13.9 0.0 1.9 7.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 CCL99759.1 - 0.02 15.2 0.0 0.048 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 CCL99759.1 - 0.022 14.3 0.0 0.083 12.4 0.0 2.0 3 0 0 3 3 1 0 AAA domain Vps4_C PF09336.5 CCL99759.1 - 0.027 14.3 0.1 0.076 12.9 0.1 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Arch_ATPase PF01637.13 CCL99759.1 - 0.037 13.7 0.0 19 4.8 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase ABC_tran PF00005.22 CCL99759.1 - 0.05 13.9 0.1 1.1 9.5 0.0 2.6 2 1 1 3 3 2 0 ABC transporter Sigma54_activat PF00158.21 CCL99759.1 - 0.052 13.0 0.0 0.65 9.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 CCL99759.1 - 0.053 12.6 0.0 3.9 6.5 0.0 2.4 2 0 0 2 2 2 0 KaiC RuBisCO_large_N PF02788.11 CCL99759.1 - 0.063 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain AFG1_ATPase PF03969.11 CCL99759.1 - 0.094 11.4 0.0 0.57 8.9 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase ResIII PF04851.10 CCL99759.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 CCL99759.1 - 0.14 11.0 0.0 0.34 9.7 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CCL99759.1 - 0.14 11.7 0.0 5 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CCL99759.1 - 0.19 10.3 0.0 0.76 8.3 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Gpi16 PF04113.9 CCL99760.1 - 1.4e-134 449.2 0.0 2.2e-134 448.5 0.0 1.3 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component AA_permease PF00324.16 CCL99761.1 - 7.3e-74 248.8 41.3 6.9e-70 235.7 17.9 2.9 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 CCL99761.1 - 4.7e-29 101.1 26.4 3e-28 98.5 18.3 2.0 1 1 0 1 1 1 1 Amino acid permease F1F0-ATPsyn_F PF10791.4 CCL99761.1 - 3.2e-23 81.7 0.1 1.1e-22 80.0 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi 2TM PF13239.1 CCL99761.1 - 4.6 7.3 7.2 4.2 7.5 0.3 3.2 2 0 0 2 2 2 0 2TM domain SPC12 PF06645.8 CCL99762.1 - 0.52 10.1 4.9 0.99 9.2 1.1 2.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Coprogen_oxidas PF01218.13 CCL99763.1 - 3.1e-111 370.6 0.0 2.8e-110 367.5 0.0 2.2 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase IMS_C PF11799.3 CCL99764.1 - 0.038 13.9 0.0 0.054 13.4 0.0 1.1 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain DUF3519 PF12033.3 CCL99765.1 - 0.06 13.5 1.2 0.099 12.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) DUF3275 PF11679.3 CCL99765.1 - 1.9 8.0 6.9 0.35 10.4 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Adeno_E3_CR2 PF02439.10 CCL99766.1 - 0.0055 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Big_3_4 PF13754.1 CCL99766.1 - 0.3 11.4 0.0 0.3 11.4 0.0 3.5 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) EB1 PF03271.12 CCL99767.1 - 6.6e-16 58.0 1.2 1.4e-15 57.0 0.9 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif Suppressor_APC PF11414.3 CCL99767.1 - 0.052 13.3 0.9 0.12 12.1 0.6 1.6 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Matrilin_ccoil PF10393.4 CCL99767.1 - 0.12 11.7 0.4 0.27 10.6 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin F-box-like PF12937.2 CCL99768.1 - 1.2e-07 31.2 0.1 2.7e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like NTR2 PF15458.1 CCL99769.1 - 0.13 11.5 0.3 0.15 11.2 0.2 1.3 1 1 0 1 1 1 0 Nineteen complex-related protein 2 DUF3498 PF12004.3 CCL99769.1 - 0.14 11.2 0.8 0.16 11.1 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Chitin_synth_1 PF01644.12 CCL99770.1 - 9.9e-88 292.0 0.1 1.8e-87 291.2 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCL99770.1 - 7.9e-31 105.5 0.1 2.5e-30 103.9 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCL99770.1 - 6.2e-23 80.9 0.0 4.6e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase MFS_1 PF07690.11 CCL99770.1 - 9e-14 50.9 66.5 6.1e-10 38.3 23.0 4.6 3 2 1 4 4 4 2 Major Facilitator Superfamily Glyco_tranf_2_3 PF13641.1 CCL99770.1 - 2.5e-06 27.4 0.0 7.1e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 UPF0542 PF15086.1 CCL99773.1 - 0.043 13.5 0.3 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 2TM PF13239.1 CCL99773.1 - 0.13 12.3 2.6 0.22 11.6 0.1 2.4 2 0 0 2 2 2 0 2TM domain DUF1049 PF06305.6 CCL99773.1 - 4.4 6.8 8.6 2.1 7.8 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) MatE PF01554.13 CCL99774.1 - 1.4e-48 164.5 28.2 5.1e-27 94.4 5.8 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 CCL99774.1 - 1.3e-07 31.4 7.7 1.3e-07 31.4 5.3 4.3 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Metallophos PF00149.23 CCL99776.1 - 2.7e-08 33.4 1.0 4.7e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCL99776.1 - 3.2e-07 30.3 0.0 1.4e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 CCL99779.1 - 2.7e-09 36.5 0.0 7.2e-06 25.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL99779.1 - 1.7e-08 34.2 0.0 8.7e-05 22.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.1 CCL99779.1 - 0.029 14.8 0.1 6.1 7.3 0.0 3.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) PGI PF00342.14 CCL99780.1 - 1.4e-211 703.1 0.0 1.6e-211 702.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase PCI PF01399.22 CCL99781.1 - 5e-06 26.7 0.1 2.2e-05 24.7 0.0 2.1 3 0 0 3 3 3 1 PCI domain Piwi PF02171.12 CCL99782.1 - 1.1e-59 201.8 0.0 1.7e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 CCL99782.1 - 2.1e-14 52.6 0.0 5.2e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 CCL99782.1 - 7.5e-12 44.7 0.1 1.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Solute_trans_a PF03619.11 CCL99783.1 - 7.5e-80 268.1 9.9 1.1e-79 267.6 6.8 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.6 CCL99783.1 - 0.0082 15.9 3.0 0.026 14.3 2.1 1.8 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1092 PF06485.6 CCL99783.1 - 0.024 13.6 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) DUF3332 PF11810.3 CCL99783.1 - 0.1 12.2 0.2 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Cys_Met_Meta_PP PF01053.15 CCL99784.1 - 3.6e-124 413.9 0.0 8e-123 409.5 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CCL99784.1 - 0.00059 18.2 0.0 0.00078 17.8 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 CCL99784.1 - 0.0035 16.3 0.0 0.0065 15.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Tocopherol_cycl PF14249.1 CCL99785.1 - 4.3e-05 22.3 2.3 0.00012 20.9 0.1 2.3 3 0 0 3 3 3 1 Tocopherol cyclase eIF3g PF12353.3 CCL99786.1 - 3.6e-42 143.3 1.5 4.9e-42 142.8 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CCL99786.1 - 1.3e-17 63.2 0.0 2.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL99786.1 - 2.6e-16 59.3 0.0 5.2e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL99786.1 - 2.6e-08 33.5 0.0 4.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HET PF06985.6 CCL99787.1 - 1.7e-19 70.3 1.4 1.2e-15 57.9 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FMN_red PF03358.10 CCL99788.1 - 4.3e-10 39.2 0.0 6.1e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CCL99788.1 - 2.6e-09 37.2 0.0 4.8e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 CCL99788.1 - 7.3e-06 25.6 0.0 8.9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 CCL99788.1 - 0.0081 16.1 0.0 0.012 15.6 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin domain DUF3112 PF11309.3 CCL99789.1 - 1 9.1 6.3 1.5 8.6 4.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Mito_carr PF00153.22 CCL99790.1 - 2.6e-58 193.7 0.9 2.9e-21 74.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Thymopoietin PF08198.6 CCL99790.1 - 0.11 12.0 0.5 13 5.4 0.0 2.6 3 0 0 3 3 3 0 Thymopoietin protein MutS_V PF00488.16 CCL99791.1 - 7.2e-98 326.6 0.0 1.4e-97 325.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCL99791.1 - 4.5e-34 118.0 5.0 5e-34 117.8 0.7 2.7 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.13 CCL99791.1 - 1.5e-17 63.4 1.4 1.5e-17 63.4 1.0 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 CCL99791.1 - 6.6e-16 58.6 0.5 9.3e-15 54.8 0.0 3.0 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 CCL99791.1 - 2.3e-09 37.2 0.0 6.2e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain I AAA_23 PF13476.1 CCL99791.1 - 1 9.6 6.6 29 4.9 1.8 3.1 3 0 0 3 3 3 0 AAA domain Pmp3 PF01679.12 CCL99792.1 - 8.5e-20 70.2 7.6 1.1e-19 69.8 5.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RRF PF01765.14 CCL99793.1 - 4.8e-26 91.1 0.6 1.3e-25 89.8 0.3 1.8 1 1 0 1 1 1 1 Ribosome recycling factor ApoLp-III PF07464.6 CCL99793.1 - 0.089 12.8 1.8 0.097 12.6 0.3 1.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) BAF1_ABF1 PF04684.8 CCL99794.1 - 0.027 13.3 9.4 0.043 12.6 6.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor IBR PF01485.16 CCL99795.1 - 2.7e-12 46.3 37.0 2.3e-08 33.7 2.6 4.6 4 1 0 4 4 4 2 IBR domain RRM_1 PF00076.17 CCL99795.1 - 6e-11 41.8 0.0 2.2e-08 33.6 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL99795.1 - 7.4e-09 35.4 0.0 4.2e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CCL99795.1 - 8.5e-09 34.8 23.7 1e-05 25.0 1.2 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_4 PF15227.1 CCL99795.1 - 6.6e-08 32.3 4.3 6.6e-08 32.3 3.0 4.3 4 1 1 5 5 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CCL99795.1 - 7.4e-07 29.0 5.2 7.4e-07 29.0 3.6 4.2 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCL99795.1 - 2.3e-06 27.1 3.4 2.3e-06 27.1 2.4 3.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCL99795.1 - 9.9e-06 25.2 5.7 9.9e-06 25.2 3.9 4.2 3 1 1 4 4 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CCL99795.1 - 0.00011 21.8 2.5 0.00011 21.8 1.8 2.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CCL99795.1 - 0.00039 20.0 4.2 0.00039 20.0 2.9 4.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCL99795.1 - 0.0016 18.0 4.5 0.0016 18.0 3.1 4.2 2 1 0 2 2 1 1 zinc-RING finger domain RRM_5 PF13893.1 CCL99795.1 - 0.0097 15.7 0.0 0.084 12.7 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PXA PF02194.10 CCL99796.1 - 0.04 13.4 1.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 PXA domain AdoHcyase PF05221.12 CCL99797.1 - 4.3e-137 455.4 0.0 4.9e-137 455.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CCL99797.1 - 1.3e-82 275.4 0.7 2e-82 274.8 0.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCL99797.1 - 6.6e-08 31.9 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 CCL99797.1 - 0.0016 18.4 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CCL99797.1 - 0.004 16.7 0.1 0.008 15.7 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 CCL99797.1 - 0.0055 16.0 0.1 0.0096 15.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 CCL99797.1 - 0.019 14.6 0.4 0.037 13.6 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TMEM107 PF14995.1 CCL99797.1 - 0.021 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein F420_oxidored PF03807.12 CCL99797.1 - 0.023 15.1 0.2 0.049 14.0 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CCL99797.1 - 0.031 14.5 0.1 0.08 13.2 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Ank_4 PF13637.1 CCL99798.1 - 3.5e-05 24.2 0.0 0.0014 19.1 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCL99798.1 - 0.015 15.6 0.0 0.034 14.4 0.0 1.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Lyase_1 PF00206.15 CCL99800.1 - 1.3e-20 73.8 0.1 4e-18 65.6 0.0 2.2 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.4 CCL99800.1 - 6.6e-18 64.5 0.0 1.5e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pkinase PF00069.20 CCL99801.1 - 4.7e-68 229.1 0.0 6.8e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99801.1 - 1.2e-37 129.4 0.0 1.8e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCL99801.1 - 1.2e-05 24.4 0.0 4.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CCL99801.1 - 0.0086 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CCL99801.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_7 PF13504.1 CCL99802.1 - 2.8 8.5 5.6 35 5.2 0.0 4.8 6 0 0 6 6 6 0 Leucine rich repeat HEM4 PF02602.10 CCL99803.1 - 6.7e-35 120.4 0.0 7.8e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD zf-H2C2 PF09337.5 CCL99804.1 - 6.6e-05 22.2 0.1 0.00012 21.3 0.1 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger SSF PF00474.12 CCL99805.1 - 2.2e-24 85.8 34.5 3.2e-24 85.3 23.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Mito_carr PF00153.22 CCL99806.1 - 2.1e-68 226.0 6.5 1.2e-22 79.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CCL99806.1 - 0.033 14.2 3.7 3.3 7.7 0.1 3.9 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Aldo_ket_red PF00248.16 CCL99807.1 - 4.5e-50 170.0 0.0 5.1e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IATP PF04568.7 CCL99808.1 - 5.8e-12 45.5 5.3 6.4e-12 45.3 3.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP YgaB PF14182.1 CCL99808.1 - 0.0052 16.9 4.1 0.0065 16.6 2.8 1.1 1 0 0 1 1 1 1 YgaB-like protein Bap31 PF05529.7 CCL99808.1 - 0.0072 15.8 3.9 0.0072 15.8 2.7 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF4140 PF13600.1 CCL99808.1 - 0.0097 16.3 2.6 0.011 16.1 1.8 1.1 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) zf-CpG_bind_C PF12269.3 CCL99808.1 - 0.018 14.4 2.5 0.022 14.2 1.7 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DP PF08781.5 CCL99808.1 - 0.064 12.9 5.2 0.046 13.4 2.9 1.4 1 1 0 1 1 1 0 Transcription factor DP LIN37 PF15306.1 CCL99808.1 - 0.11 12.5 2.6 0.12 12.3 1.8 1.1 1 0 0 1 1 1 0 LIN37 SpoOE-like PF09388.5 CCL99808.1 - 0.12 11.8 2.0 0.21 11.1 1.4 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein YqfQ PF14181.1 CCL99808.1 - 0.12 12.3 4.6 0.15 12.1 3.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF3573 PF12097.3 CCL99808.1 - 0.19 10.3 0.6 0.21 10.1 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Mnd1 PF03962.10 CCL99808.1 - 0.2 11.2 6.4 0.22 11.1 4.4 1.1 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 CCL99808.1 - 1.4 8.4 5.9 2.1 7.8 4.0 1.4 1 1 0 1 1 1 0 Septum formation initiator ATP_sub_h PF10775.4 CCL99809.1 - 1.1e-22 79.4 0.9 1.6e-22 78.9 0.7 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 CCL99809.1 - 0.058 13.3 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Histone PF00125.19 CCL99810.1 - 1.3e-22 79.6 0.1 1.8e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCL99810.1 - 0.015 15.2 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNA_pol PF00940.14 CCL99811.1 - 9.8e-165 547.9 0.0 1.3e-164 547.5 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CCL99811.1 - 5.6e-73 245.9 0.9 8.4e-73 245.3 0.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal SUR7 PF06687.7 CCL99812.1 - 4.4e-08 32.9 17.3 5.5e-06 26.0 8.7 2.2 1 1 1 2 2 2 2 SUR7/PalI family CsbD PF05532.7 CCL99813.1 - 0.00044 19.8 8.0 0.0011 18.6 5.5 1.7 1 0 0 1 1 1 1 CsbD-like BTB PF00651.26 CCL99814.1 - 8.4e-22 77.2 0.6 1.7e-09 37.6 0.1 3.2 4 0 0 4 4 4 2 BTB/POZ domain Skp1_POZ PF03931.10 CCL99814.1 - 0.0014 18.6 0.2 0.75 9.9 0.0 2.7 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Adaptin_N PF01602.15 CCL99815.1 - 6.3e-149 496.6 7.5 8.2e-149 496.2 5.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCL99815.1 - 2.9e-27 95.6 4.7 9.9e-25 87.4 0.4 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCL99815.1 - 1.2e-19 70.3 2.4 4e-09 36.6 0.0 5.6 1 1 5 6 6 6 6 HEAT repeats HEAT PF02985.17 CCL99815.1 - 3e-08 33.0 15.4 0.00023 20.9 0.1 6.7 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 CCL99815.1 - 1.2e-06 28.8 7.6 0.0035 17.7 0.1 6.4 6 2 2 8 8 8 2 HEAT-like repeat CLASP_N PF12348.3 CCL99815.1 - 0.0003 20.2 1.0 0.26 10.5 0.0 3.9 3 1 2 5 5 5 2 CLASP N terminal FAD_binding_1 PF00667.15 CCL99816.1 - 1.7e-39 135.5 0.0 2.8e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCL99816.1 - 7.2e-25 87.6 0.0 1.5e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCL99816.1 - 5e-10 39.9 0.0 1.3e-09 38.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 CCL99816.1 - 0.015 15.3 0.1 0.037 14.0 0.1 1.7 1 0 0 1 1 1 0 Flavodoxin domain SBP_bac_5 PF00496.17 CCL99816.1 - 0.026 13.3 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle SNase PF00565.12 CCL99817.1 - 7.2e-16 58.3 0.0 1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Nha1_C PF08619.5 CCL99817.1 - 0.023 13.9 0.6 0.029 13.6 0.4 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Beta-lactamase PF00144.19 CCL99818.1 - 2.9e-43 148.1 0.1 4.5e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF4421 PF14391.1 CCL99818.1 - 0.0064 15.7 0.0 0.0095 15.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4421) DUF3471 PF11954.3 CCL99818.1 - 0.0091 15.8 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase PF00144.19 CCL99820.1 - 2.9e-38 131.7 0.4 4.8e-38 131.0 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 CCL99820.1 - 0.025 14.3 0.1 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) DUF4421 PF14391.1 CCL99820.1 - 0.026 13.7 0.3 0.04 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) Abhydrolase_6 PF12697.2 CCL99821.1 - 1.2e-22 80.9 0.1 1.4e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL99821.1 - 1.4e-11 44.3 0.0 7.2e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCL99821.1 - 1.5e-07 31.2 0.0 3.9e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCL99821.1 - 0.027 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 CCL99821.1 - 0.058 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF1057 PF06342.7 CCL99821.1 - 0.084 11.6 0.0 0.18 10.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.20 CCL99821.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) HET PF06985.6 CCL99822.1 - 5.4e-24 84.9 0.1 1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.18 CCL99823.1 - 4.2e-71 239.1 0.0 5.8e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCL99823.1 - 2e-08 33.9 0.0 7.2e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCL99823.1 - 2.8e-06 27.2 0.0 5.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 CCL99823.1 - 1.6e-05 24.5 1.8 1.6e-05 24.5 1.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CCL99823.1 - 3.6e-05 23.3 0.2 3.6e-05 23.3 0.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CCL99823.1 - 0.0002 20.9 0.8 0.0002 20.9 0.5 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCL99823.1 - 0.0011 18.8 2.0 0.0011 18.8 1.4 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCL99823.1 - 0.0019 17.8 2.3 0.0019 17.8 1.6 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCL99823.1 - 0.0022 17.8 1.7 0.0022 17.8 1.2 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF3638 PF12340.3 CCL99823.1 - 0.045 12.7 0.1 0.1 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) TerY-C PF15616.1 CCL99823.1 - 0.57 10.1 3.4 0.74 9.7 0.3 2.3 1 1 1 2 2 2 0 TerY-C metal binding domain IBR PF01485.16 CCL99823.1 - 1.3 8.9 5.2 3 7.7 0.8 2.9 2 1 0 2 2 2 0 IBR domain p450 PF00067.17 CCL99826.1 - 2.7e-74 250.3 0.0 3.1e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SSF PF00474.12 CCL99827.1 - 4.5e-22 78.2 26.9 7.7e-22 77.4 18.7 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4179 PF13786.1 CCL99827.1 - 1.1 9.5 3.0 3.8 7.8 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DPBB_1 PF03330.13 CCL99828.1 - 0.00011 22.1 1.5 0.00024 21.0 0.0 2.1 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CCL99828.1 - 0.00092 18.8 0.1 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Barwin family PseudoU_synth_2 PF00849.17 CCL99829.1 - 2.1e-20 73.1 0.0 3.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase P16-Arc PF04699.9 CCL99834.1 - 1e-41 142.5 0.0 1.5e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) F-box PF00646.28 CCL99834.1 - 1.5e-06 27.6 0.1 3e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCL99834.1 - 0.00052 19.6 0.1 0.0012 18.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 CCL99835.1 - 6.2e-08 32.2 2.5 0.00036 20.3 0.1 3.5 2 1 0 2 2 2 2 WD domain, G-beta repeat UIM PF02809.15 CCL99835.1 - 0.0014 18.0 0.5 0.0014 18.0 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin interaction motif HNH_2 PF13391.1 CCL99836.1 - 0.0093 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease LIF_OSM PF01291.12 CCL99837.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 LIF / OSM family RR_TM4-6 PF06459.7 CCL99838.1 - 0.09 12.6 16.9 0.11 12.4 11.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H2-Ydr279 PF09468.5 CCL99838.1 - 0.25 10.5 16.1 0.31 10.2 11.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) NARP1 PF12569.3 CCL99838.1 - 0.91 8.2 17.5 1 8.0 12.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.7 CCL99838.1 - 1 8.5 19.7 1.3 8.1 13.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2201_N PF13203.1 CCL99838.1 - 1.1 8.3 9.1 1.2 8.2 6.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain TP53IP5 PF15331.1 CCL99838.1 - 1.5 8.6 14.3 2 8.2 9.9 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF2413 PF10310.4 CCL99838.1 - 1.6 7.4 17.2 1.9 7.2 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DDHD PF02862.12 CCL99838.1 - 2.6 7.8 7.6 2.8 7.6 5.2 1.2 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 CCL99838.1 - 3.3 7.7 22.4 4.2 7.3 15.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RP-C_C PF11800.3 CCL99838.1 - 5.2 6.7 7.9 6.8 6.3 5.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region MIP-T3 PF10243.4 CCL99838.1 - 5.8 5.2 28.5 7 4.9 19.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 CCL99838.1 - 6 6.1 20.0 7.9 5.7 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) YqfQ PF14181.1 CCL99838.1 - 7 6.6 19.8 9.8 6.1 13.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein Borrelia_P83 PF05262.6 CCL99838.1 - 8.3 4.5 18.7 9.6 4.3 13.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FAD_binding_3 PF01494.14 CCL99839.1 - 3.8e-28 98.5 0.0 6.4e-28 97.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCL99839.1 - 0.00011 21.2 0.3 0.18 10.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCL99839.1 - 0.017 15.4 0.1 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCL99839.1 - 0.17 11.7 0.3 0.42 10.4 0.2 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 CCL99839.1 - 0.17 10.6 0.0 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase CAF1A PF12253.3 CCL99840.1 - 0.076 13.1 2.7 0.2 11.7 1.8 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A DUF790 PF05626.6 CCL99841.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Pkinase PF00069.20 CCL99842.1 - 1.3e-61 208.0 0.0 1.6e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99842.1 - 1.8e-30 105.8 0.0 2.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCL99842.1 - 4.8e-08 32.2 0.0 9.9e-08 31.2 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCL99842.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCL99842.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ALS_ss_C PF10369.4 CCL99843.1 - 7.5e-20 70.4 0.0 8.7e-18 63.8 0.0 2.4 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 CCL99843.1 - 8.5e-12 44.3 0.1 1.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 CCL99843.1 - 2.7e-08 33.4 0.1 5.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 ACT domain COG5 PF10392.4 CCL99844.1 - 7.2e-30 103.6 0.5 1.9e-28 99.0 0.2 2.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 CCL99844.1 - 5.9e-06 26.0 0.1 4.9e-05 23.0 0.0 2.6 1 1 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 CCL99844.1 - 0.2 11.5 2.8 1.7 8.5 0.7 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fungal_trans PF04082.13 CCL99846.1 - 0.00014 20.8 0.1 0.00014 20.8 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain TPT PF03151.11 CCL99847.1 - 5.3e-33 113.8 5.0 5.3e-33 113.8 3.4 2.4 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CCL99847.1 - 2.1e-09 37.4 25.6 4.3e-06 26.7 7.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CCL99847.1 - 1.1e-06 27.8 16.0 3e-06 26.3 11.1 1.8 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CCL99847.1 - 0.17 12.0 28.1 0.37 10.9 6.2 3.2 2 2 1 3 3 3 0 Multidrug resistance efflux transporter PDR_CDR PF06422.7 CCL99847.1 - 0.37 10.4 1.2 0.87 9.2 0.8 1.5 1 0 0 1 1 1 0 CDR ABC transporter Med31 PF05669.7 CCL99848.1 - 2.1e-34 117.3 4.4 2.5e-34 117.0 3.1 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.6 CCL99848.1 - 0.013 15.1 2.2 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 Nodule-specific GRP repeat Peptidase_C12 PF01088.16 CCL99849.1 - 3.4e-53 180.0 0.0 6.3e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CHAD PF05235.9 CCL99849.1 - 0.063 12.8 4.7 0.087 12.3 3.3 1.2 1 0 0 1 1 1 0 CHAD domain DUF3897 PF13036.1 CCL99849.1 - 0.13 11.8 0.3 0.24 11.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3897) AA_permease PF00324.16 CCL99850.1 - 5.5e-94 315.1 44.6 1.6e-92 310.3 30.9 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCL99850.1 - 6.6e-25 87.5 46.7 6.6e-22 77.6 32.7 2.6 2 1 0 2 2 2 1 Amino acid permease NTP_transferase PF00483.18 CCL99851.1 - 6.6e-42 143.5 0.0 1.3e-41 142.5 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCL99851.1 - 2.3e-06 27.7 0.1 4.8e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 CCL99851.1 - 0.00012 21.7 0.1 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.14 CCL99851.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CCDC92 PF14916.1 CCL99851.1 - 0.025 14.1 2.0 0.18 11.4 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function EBP50_C-term PF09007.6 CCL99852.1 - 0.12 12.2 0.6 0.32 10.8 0.4 1.7 1 0 0 1 1 1 0 EBP50, C-terminal AAA_18 PF13238.1 CCL99853.1 - 1.1e-09 38.6 0.1 4.6e-09 36.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCL99853.1 - 5.5e-08 33.6 0.1 5.3e-07 30.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CCL99853.1 - 4.9e-06 26.2 0.1 1.2e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 CCL99853.1 - 0.0001 22.2 0.0 0.00028 20.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCL99853.1 - 0.019 14.9 0.0 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCL99853.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin FAD_binding_2 PF00890.19 CCL99854.1 - 6.4e-91 305.2 0.9 8.1e-91 304.9 0.4 1.3 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.23 CCL99854.1 - 1.2e-21 76.2 0.0 2.5e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 CCL99854.1 - 4.4e-13 48.8 0.3 3.3e-09 36.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCL99854.1 - 7.4e-12 45.5 0.9 5.5e-08 32.9 0.7 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCL99854.1 - 2.4e-10 40.3 0.1 2.8e-09 36.8 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CCL99854.1 - 2.9e-08 33.2 1.4 6.2e-08 32.1 1.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCL99854.1 - 1.7e-07 30.6 0.2 2.9e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CCL99854.1 - 2.6e-06 27.6 0.3 7e-06 26.2 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCL99854.1 - 3.9e-06 25.9 1.3 0.00012 21.0 0.3 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 CCL99854.1 - 4.8e-06 25.2 4.1 0.00016 20.3 0.3 3.0 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 CCL99854.1 - 8.7e-06 24.9 0.6 0.0039 16.3 0.2 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.1 CCL99854.1 - 1.7e-05 24.6 0.3 0.00021 21.1 0.1 2.5 2 1 0 2 2 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CCL99854.1 - 0.0022 17.0 0.1 0.0085 15.0 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 CCL99854.1 - 0.0056 17.0 0.3 0.038 14.3 0.0 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CCL99854.1 - 0.012 15.1 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 CCL99854.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 CCL99854.1 - 0.032 13.3 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 CCL99854.1 - 0.062 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HAD_2 PF13419.1 CCL99859.1 - 2e-12 47.6 0.0 5.6e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCL99859.1 - 8.5e-09 35.0 0.0 1.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCL99859.1 - 2.3e-05 24.9 0.0 4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_2 PF04059.7 CCL99860.1 - 1.5e-20 73.0 0.1 3.1e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 CCL99860.1 - 1.8e-11 43.4 0.0 9.5e-05 21.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCL99860.1 - 6.5e-07 29.2 0.1 0.0013 18.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCL99860.1 - 1.2e-06 28.2 0.2 0.012 15.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_4 PF07993.7 CCL99861.1 - 3.7e-27 94.8 0.0 1.5e-26 92.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CCL99861.1 - 0.00033 20.1 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCL99861.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CCL99861.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_S6 PF01250.12 CCL99862.1 - 9.7e-09 34.9 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 SNase PF00565.12 CCL99863.1 - 1.1e-54 183.2 0.6 3.6e-18 65.7 0.0 6.1 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 CCL99863.1 - 4.7e-21 74.8 0.0 9.2e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Tudor domain PIF1 PF05970.9 CCL99864.1 - 1.8e-71 241.0 0.0 2.4e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Aldo_ket_red PF00248.16 CCL99864.1 - 1.8e-52 177.9 0.0 3.2e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family AAA_30 PF13604.1 CCL99864.1 - 5.5e-06 26.0 0.0 1.6e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CCL99864.1 - 0.00029 19.9 0.0 0.01 14.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CCL99864.1 - 0.0032 17.1 0.0 0.038 13.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 CCL99864.1 - 0.028 14.3 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF2791 PF10923.3 CCL99864.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) NACHT PF05729.7 CCL99864.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 CCL99864.1 - 0.22 10.4 0.0 0.39 9.6 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain Peptidase_M19 PF01244.16 CCL99865.1 - 3.4e-99 331.8 0.0 4.1e-99 331.5 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF647 PF04884.9 CCL99865.1 - 0.059 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis FA_desaturase PF00487.19 CCL99866.1 - 6.5e-21 74.9 24.6 1.9e-19 70.1 17.0 2.2 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CCL99866.1 - 4.6e-05 23.4 0.1 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Amidohydro_2 PF04909.9 CCL99867.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase Yae1_N PF09811.4 CCL99868.1 - 3.5e-09 36.0 26.5 0.066 12.7 14.5 3.9 2 1 0 2 2 2 1 Essential protein Yae1, N terminal SPAN-X PF07458.7 CCL99868.1 - 0.22 11.7 3.4 0.65 10.2 0.8 2.6 1 1 1 3 3 3 0 Sperm protein associated with nucleus, mapped to X chromosome V_ATPase_I PF01496.14 CCL99868.1 - 2.8 5.6 4.9 3.8 5.2 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Trypan_PARP PF05887.6 CCL99868.1 - 4.4 7.1 17.0 0.14 12.0 7.0 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Macoilin PF09726.4 CCL99868.1 - 7.5 4.6 16.0 10 4.2 11.1 1.1 1 0 0 1 1 1 0 Transmembrane protein MIF4G PF02854.14 CCL99869.1 - 8e-46 156.0 0.2 8.6e-27 93.9 0.0 4.5 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 CCL99869.1 - 2.6e-25 89.1 5.0 2.6e-25 89.1 3.5 3.5 4 0 0 4 4 4 1 Up-frameshift suppressor 2 adh_short PF00106.20 CCL99871.1 - 2.9e-18 66.3 0.1 4.1e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCL99871.1 - 1.3e-08 34.9 0.1 1.8e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 CCL99871.1 - 0.0015 17.7 0.0 0.0094 15.1 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 CCL99871.1 - 0.0031 17.1 0.2 0.014 15.1 0.1 2.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCL99871.1 - 0.0066 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 CCL99871.1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Mito_carr PF00153.22 CCL99872.1 - 4.8e-37 125.5 0.7 1.2e-13 50.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2992 PF11208.3 CCL99873.1 - 0.4 10.5 6.8 1.1 9.2 4.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) ubiquitin PF00240.18 CCL99875.1 - 1.1e-137 447.5 21.2 5.5e-34 115.3 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 CCL99875.1 - 7.7e-78 256.1 20.9 6e-19 67.5 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCL99875.1 - 1.9e-24 85.7 10.2 0.00012 22.2 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCL99875.1 - 3.8e-21 75.4 0.7 0.0018 17.9 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCL99875.1 - 4.1e-14 52.3 3.1 0.11 12.4 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCL99875.1 - 1.1e-13 51.1 1.8 0.15 12.2 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCL99875.1 - 1.4e-10 41.1 0.0 1.6 8.8 0.0 4.8 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 CCL99875.1 - 1.5e-07 31.0 4.5 3.6 7.4 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 CCL99875.1 - 9.1e-07 28.2 0.6 1.1 8.3 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 CCL99875.1 - 3.5e-06 26.8 4.8 6.6 6.7 0.0 4.2 4 0 0 4 4 4 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 CCL99875.1 - 0.00057 20.1 1.4 38 4.7 0.1 4.2 4 0 0 4 4 4 0 ACT domain Big_3_3 PF13750.1 CCL99875.1 - 0.0014 18.0 0.0 51 3.2 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 CCL99875.1 - 0.0019 16.6 13.7 4.1 5.6 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain ACP PF06857.6 CCL99875.1 - 0.0078 16.0 6.2 0.7 9.8 0.3 4.6 4 0 0 4 4 4 1 Malonate decarboxylase delta subunit (MdcD) DUF3861 PF12977.2 CCL99875.1 - 0.015 15.3 5.6 59 3.8 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 CCL99875.1 - 0.019 14.8 13.9 9.2 6.2 0.2 4.6 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 CCL99875.1 - 0.027 14.3 29.1 3.6 7.6 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 CCL99875.1 - 0.053 13.5 7.0 55 3.8 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain Corona_NS2A PF05213.7 CCL99875.1 - 0.068 12.4 0.0 91 2.2 0.0 3.7 1 1 0 4 4 4 0 Coronavirus NS2A protein CDC48_2 PF02933.12 CCL99875.1 - 0.79 9.4 12.3 41 3.9 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 FERM_N PF09379.5 CCL99875.1 - 1.5 8.8 12.5 89 3.2 0.1 5.8 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 CCL99875.1 - 2.3 8.2 7.0 1.7e+02 2.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Ribosomal_S4e PF00900.15 CCL99875.1 - 9.8 5.9 9.2 1.7e+02 1.9 0.1 4.8 4 0 0 4 4 4 0 Ribosomal family S4e CHAT PF12770.2 CCL99877.1 - 1.4e-33 116.2 0.0 2.7e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.1 CCL99877.1 - 9.2 6.3 8.3 5.2 7.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.2 CCL99878.1 - 0.042 13.5 0.3 0.11 12.1 0.2 1.8 1 0 0 1 1 1 0 F-box-like LRR_2 PF07723.8 CCL99878.1 - 0.065 13.7 0.4 0.46 11.0 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich Repeat LANC_like PF05147.8 CCL99882.1 - 1.7e-07 30.1 0.0 3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein TEX19 PF15553.1 CCL99882.1 - 0.089 12.6 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Glyoxal_oxid_N PF07250.6 CCL99883.1 - 5.9e-35 120.4 0.0 2.2e-32 112.0 0.0 3.9 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CCL99883.1 - 4.8e-20 71.4 0.2 4.8e-20 71.4 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.11 CCL99883.1 - 0.042 12.1 0.0 0.065 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.1 CCL99883.1 - 0.24 11.2 14.9 1 9.1 0.1 6.0 6 0 0 6 6 6 0 Galactose oxidase, central domain Pkinase PF00069.20 CCL99884.1 - 3.7e-30 104.9 0.0 7.9e-30 103.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99884.1 - 1.1e-12 47.5 0.0 3e-06 26.4 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase RIO1 PF01163.17 CCL99884.1 - 0.038 13.3 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ATG13 PF10033.4 CCL99885.1 - 3.7e-34 118.1 0.0 5.2e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 Oxidored_FMN PF00724.15 CCL99889.1 - 1.3e-105 353.1 0.0 1.5e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 CCL99890.1 - 3.3e-106 355.1 0.0 3.8e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 CCL99891.1 - 3.3e-100 335.3 0.0 3.8e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CPL PF08144.6 CCL99892.1 - 2.2e-23 82.7 3.4 6.7e-22 77.9 0.0 4.2 3 2 2 5 5 5 1 CPL (NUC119) domain BING4CT PF08149.6 CCL99893.1 - 6.4e-34 115.3 0.0 4.5e-33 112.6 0.0 2.4 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 CCL99893.1 - 2.8e-09 36.5 0.0 1.5e-07 31.0 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat YL1_C PF08265.6 CCL99894.1 - 3.1e-14 52.1 0.1 5.4e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CDC27 PF09507.5 CCL99894.1 - 0.085 12.0 1.3 0.1 11.8 0.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dna2 PF08696.6 CCL99895.1 - 1.8e-52 177.6 0.1 6e-52 175.9 0.0 1.9 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 CCL99895.1 - 1.1e-49 168.5 0.1 1.7e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCL99895.1 - 1.2e-40 139.6 0.1 2.4e-37 128.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCL99895.1 - 1.8e-12 47.2 0.0 6.2e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCL99895.1 - 2.6e-09 36.6 0.1 9.4e-09 34.9 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 CCL99895.1 - 8.3e-06 25.3 0.0 3e-05 23.5 0.0 2.0 2 1 0 2 2 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 CCL99895.1 - 3e-05 23.6 0.4 0.3 10.5 0.0 3.2 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 CCL99895.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Helicase AAA PF00004.24 CCL99895.1 - 0.00036 20.7 0.2 0.0065 16.6 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Cas_Cas4 PF01930.12 CCL99895.1 - 0.00086 19.2 0.0 0.0045 16.9 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function DUF83 ResIII PF04851.10 CCL99895.1 - 0.0026 17.6 0.1 0.0098 15.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 CCL99895.1 - 0.003 16.9 0.5 0.013 14.8 0.1 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 CCL99895.1 - 0.0033 17.4 0.5 0.016 15.1 0.1 2.4 2 1 0 2 2 1 1 AAA ATPase domain SRP54 PF00448.17 CCL99895.1 - 0.0071 15.8 0.3 0.027 13.9 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 CCL99895.1 - 0.0077 15.9 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 CCL99895.1 - 0.0091 15.0 0.0 0.025 13.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 CCL99895.1 - 0.01 15.2 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 CCL99895.1 - 0.011 14.7 0.1 0.98 8.2 0.1 2.4 2 0 0 2 2 2 0 PIF1-like helicase DUF87 PF01935.12 CCL99895.1 - 0.018 14.8 0.4 0.039 13.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 CCL99895.1 - 0.024 14.0 0.1 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ArgK PF03308.11 CCL99895.1 - 0.031 13.0 0.3 0.09 11.5 0.0 1.8 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 CCL99895.1 - 0.039 13.4 0.1 0.088 12.2 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 CCL99895.1 - 0.056 13.1 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 CCL99895.1 - 0.068 12.0 0.0 0.16 10.8 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CCL99895.1 - 0.078 12.5 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CCL99895.1 - 0.08 12.8 0.1 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCL99895.1 - 0.09 13.0 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 CCL99895.1 - 0.13 12.4 0.0 0.55 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 CCL99895.1 - 0.46 9.4 0.0 0.7 8.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ECH PF00378.15 CCL99896.1 - 3.2e-61 206.5 0.0 3.8e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Totivirus_coat PF05518.6 CCL99897.1 - 8 4.1 7.1 13 3.4 4.9 1.2 1 0 0 1 1 1 0 Totivirus coat protein MFS_1 PF07690.11 CCL99898.1 - 4.1e-20 71.8 28.4 2.3e-19 69.3 20.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 CCL99899.1 - 1.4e-19 70.0 31.6 4.8e-19 68.2 21.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 CCL99900.1 - 8.1e-24 83.9 29.8 8.1e-24 83.9 20.7 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily AAA PF00004.24 CCL99901.1 - 2.1e-12 47.3 0.0 4.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCL99901.1 - 0.00095 18.8 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCL99901.1 - 0.0028 17.7 0.2 0.13 12.3 0.1 3.3 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.1 CCL99901.1 - 0.0084 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CCL99901.1 - 0.048 12.4 0.0 0.086 11.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 CCL99901.1 - 0.13 12.2 1.1 0.56 10.1 0.1 2.4 3 1 1 4 4 4 0 AAA ATPase domain Xan_ur_permease PF00860.15 CCL99902.1 - 4.7e-56 189.9 32.6 4.7e-56 189.9 22.6 2.5 2 1 0 2 2 2 1 Permease family RE_Alw26IDE PF09665.5 CCL99909.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Retinal PF15449.1 CCL99909.1 - 8.5 3.8 8.5 11 3.4 5.9 1.1 1 0 0 1 1 1 0 Retinal protein GST_N PF02798.15 CCL99910.1 - 2.3e-15 56.4 0.0 5.7e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCL99910.1 - 1.1e-13 51.0 0.0 2.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCL99910.1 - 1.7e-12 47.1 0.0 4.8e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCL99910.1 - 7.3e-12 45.3 0.0 1.5e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCL99910.1 - 2.4e-07 30.5 0.0 1.3e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCL99910.1 - 0.00029 21.2 0.0 0.00075 19.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tim17 PF02466.14 CCL99910.1 - 0.3 11.1 5.7 9 6.3 0.1 3.9 4 1 1 5 5 5 0 Tim17/Tim22/Tim23/Pmp24 family GST_N_3 PF13417.1 CCL99911.1 - 4.3e-12 46.0 0.0 6.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCL99911.1 - 6.6e-12 45.4 0.0 1.9e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCL99911.1 - 1.3e-11 44.3 0.1 4.1e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCL99911.1 - 1.3e-09 37.9 0.0 2.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCL99911.1 - 7.1e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3791 PF12668.2 CCL99911.1 - 0.03 13.9 0.2 0.077 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) GST_C_3 PF14497.1 CCL99911.1 - 0.038 14.4 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WWbp PF10349.4 CCL99912.1 - 0.39 11.6 10.4 0.58 11.0 7.2 1.3 1 0 0 1 1 1 0 WW-domain ligand protein Y_phosphatase PF00102.22 CCL99913.1 - 4e-38 131.0 0.0 6.3e-32 110.8 0.0 2.7 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCL99913.1 - 2.1e-07 31.0 0.1 0.00016 21.7 0.0 2.7 3 0 0 3 3 3 2 Inositol hexakisphosphate DSPc PF00782.15 CCL99913.1 - 0.00072 19.1 0.0 0.0049 16.4 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCL99913.1 - 0.00092 19.4 0.1 0.0031 17.8 0.1 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF3093 PF11292.3 CCL99913.1 - 0.085 12.6 0.3 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) DUF4414 PF14377.1 CCL99913.1 - 0.1 12.5 0.5 0.36 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) His_Phos_2 PF00328.17 CCL99914.1 - 2.2e-26 93.0 0.0 2.8e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NTP_transf_3 PF12804.2 CCL99914.1 - 0.049 13.6 0.1 0.087 12.8 0.1 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Mo25 PF08569.6 CCL99916.1 - 3.5e-124 414.1 3.1 3.9e-124 414.0 2.2 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 CCL99916.1 - 0.063 13.5 0.0 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 HEAT repeats adh_short PF00106.20 CCL99917.1 - 2.9e-21 76.0 0.0 4.2e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCL99917.1 - 1.1e-19 71.1 0.0 1.4e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCL99917.1 - 2.2e-11 43.7 0.0 3.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Uricase PF01014.13 CCL99918.1 - 6.3e-58 194.7 0.6 1.7e-33 115.5 0.4 2.5 2 0 0 2 2 2 2 Uricase DUF4611 PF15387.1 CCL99918.1 - 0.068 13.3 0.2 13 5.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ATP-synt_G PF04718.10 CCL99919.1 - 2.6e-06 28.0 0.6 7.3e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit PH PF00169.24 CCL99919.1 - 0.001 19.2 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 PH domain SidE PF12252.3 CCL99919.1 - 0.045 11.0 1.4 0.36 8.0 0.3 2.0 1 1 0 2 2 2 0 Dot/Icm substrate protein DUF2890 PF11081.3 CCL99919.1 - 3.2 7.7 9.0 7.1 6.6 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SNARE_assoc PF09335.6 CCL99920.1 - 3.6e-15 56.2 7.7 3.6e-15 56.2 5.3 3.0 2 1 1 3 3 3 1 SNARE associated Golgi protein Abhydrolase_6 PF12697.2 CCL99921.1 - 8.4e-21 74.9 0.2 1.8e-20 73.8 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCL99921.1 - 1.3e-08 34.7 0.1 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCL99921.1 - 5.5e-05 22.8 0.0 0.00018 21.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold F-box-like PF12937.2 CCL99921.1 - 7.5e-05 22.3 0.2 0.00018 21.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like Thioesterase PF00975.15 CCL99921.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 CCL99921.1 - 0.006 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.5 CCL99921.1 - 0.16 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) zf-CCCH PF00642.19 CCL99923.1 - 2.6e-13 49.2 15.5 3.2e-06 26.6 0.3 4.1 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCL99923.1 - 0.00023 21.0 28.4 0.01 15.7 1.9 4.8 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type FliJ PF02050.11 CCL99924.1 - 0.0027 17.7 0.6 0.0027 17.7 0.4 2.8 3 0 0 3 3 3 1 Flagellar FliJ protein IncA PF04156.9 CCL99924.1 - 1.9 8.0 4.7 0.79 9.2 0.2 2.2 2 0 0 2 2 2 0 IncA protein zf-C3HC4 PF00097.20 CCL99925.1 - 1.8e-06 27.5 5.2 3.8e-06 26.4 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCL99925.1 - 3e-06 27.1 5.9 6e-06 26.1 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCL99925.1 - 4.7e-06 26.1 4.0 8.8e-06 25.2 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCL99925.1 - 5.8e-05 22.8 4.4 0.00014 21.5 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCL99925.1 - 8.8e-05 22.1 6.3 8.8e-05 22.1 4.3 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCL99925.1 - 0.0027 17.3 3.4 0.0063 16.2 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCL99925.1 - 1.6 8.6 10.2 1.2 9.0 5.7 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING COPIIcoated_ERV PF07970.7 CCL99926.1 - 1.7e-35 122.6 1.1 2.6e-35 122.0 0.8 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCL99926.1 - 4.1e-19 68.3 0.0 7.6e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Hus1 PF04005.7 CCL99927.1 - 3.7e-70 236.1 0.0 4.1e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Isochorismatase PF00857.15 CCL99928.1 - 3.2e-14 53.2 0.0 4.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Maf PF02545.9 CCL99930.1 - 3.4e-42 143.7 0.0 7e-24 84.0 0.0 2.0 2 0 0 2 2 2 2 Maf-like protein SKIP_SNW PF02731.10 CCL99931.1 - 0.017 14.6 0.2 0.019 14.4 0.1 1.1 1 0 0 1 1 1 0 SKIP/SNW domain Glutaredoxin PF00462.19 CCL99932.1 - 9.2e-18 64.0 0.0 1.9e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CCL99932.1 - 3.9e-17 61.8 0.0 1.1e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.6 CCL99932.1 - 5.9e-05 22.9 0.1 0.00046 20.0 0.0 2.3 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.1 CCL99932.1 - 9.5e-05 22.4 0.0 0.0051 16.8 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like GST_N_3 PF13417.1 CCL99932.1 - 0.00035 20.7 0.0 0.00068 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 CCL99932.1 - 0.0036 17.4 0.0 0.048 13.8 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Phosducin PF02114.11 CCL99932.1 - 0.0088 14.7 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.1 CCL99932.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin domain Ku PF02735.11 CCL99933.1 - 1.2e-26 93.4 0.0 2.2e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CCL99933.1 - 8.3e-18 64.6 0.0 1.6e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 CCL99933.1 - 3.4e-05 23.2 0.2 0.0002 20.7 0.0 2.3 2 0 0 2 2 2 1 SAP domain VWA_2 PF13519.1 CCL99933.1 - 0.035 14.2 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain PTPA PF03095.10 CCL99934.1 - 1.5e-89 300.1 0.0 2.1e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Orn_Arg_deC_N PF02784.11 CCL99934.1 - 2.3e-72 243.1 0.0 3.2e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CCL99934.1 - 8e-29 99.7 0.0 1.9e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain KilA-N PF04383.8 CCL99934.1 - 0.38 10.3 0.1 2 8.0 0.1 2.0 1 1 0 1 1 1 0 KilA-N domain HSP70 PF00012.15 CCL99935.1 - 0.0011 16.9 0.1 0.0011 16.9 0.1 2.0 2 0 0 2 2 2 1 Hsp70 protein Zn_clus PF00172.13 CCL99936.1 - 1.9e-08 34.0 9.7 2.8e-08 33.5 6.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.9 CCL99937.1 - 2.7e-49 167.9 0.0 3.2e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F-box-like PF12937.2 CCL99938.1 - 1.2e-07 31.3 0.2 6.2e-07 29.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CCL99938.1 - 0.28 10.8 5.5 28 4.4 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) UCH PF00443.24 CCL99939.1 - 1.3e-30 106.4 0.0 2.4e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCL99939.1 - 1.2e-26 92.6 14.7 1.9e-21 75.9 1.6 2.7 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CCL99939.1 - 3.9e-10 39.2 0.5 8.2e-10 38.2 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UCH_1 PF13423.1 CCL99939.1 - 1.8e-05 24.3 0.0 5.4e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF695 PF05117.7 CCL99939.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF695) Ribosomal_L5_C PF00673.16 CCL99939.1 - 0.11 12.2 0.1 0.78 9.5 0.0 2.3 3 0 0 3 3 3 0 ribosomal L5P family C-terminus RE_MamI PF09567.5 CCL99939.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 MamI restriction endonuclease UCH PF00443.24 CCL99940.1 - 2.5e-14 53.0 0.0 2.5e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 CCL99940.1 - 1.8e-13 49.8 0.0 3.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UCH_1 PF13423.1 CCL99940.1 - 5.9e-10 39.0 0.0 6.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 CCL99940.1 - 0.037 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain NAP PF00956.13 CCL99941.1 - 2.9e-78 262.3 4.0 2.9e-78 262.3 2.8 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Snapin_Pallidin PF14712.1 CCL99941.1 - 0.046 14.0 0.3 0.12 12.6 0.2 1.7 1 0 0 1 1 1 0 Snapin/Pallidin zf-4CXXC_R1 PF10497.4 CCL99942.1 - 3e-08 33.7 14.6 8e-08 32.3 10.1 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 GAS PF13851.1 CCL99943.1 - 0.27 10.4 5.6 6 6.0 0.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 CCL99943.1 - 2.6 7.8 10.8 0.83 9.5 5.2 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 CCL99943.1 - 2.7 6.9 7.5 5.2 6.0 3.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 HAD_2 PF13419.1 CCL99944.1 - 5.8e-22 78.7 0.4 2.7e-21 76.5 0.3 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCL99944.1 - 2.4e-10 41.2 0.0 1.9e-09 38.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCL99944.1 - 2.2e-05 24.0 0.0 4.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like dCMP_cyt_deam_1 PF00383.17 CCL99945.1 - 1.3e-16 60.0 0.0 6e-16 57.9 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 CCL99945.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 CCL99945.1 - 0.028 14.0 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 CCL99945.1 - 0.042 13.7 0.1 0.074 12.9 0.1 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase FMO-like PF00743.14 CCL99946.1 - 7.7e-21 73.8 0.1 1.8e-16 59.4 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCL99946.1 - 2.8e-20 73.2 0.2 1.2e-19 71.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCL99946.1 - 5.8e-12 45.1 0.0 3.1e-09 36.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCL99946.1 - 2.9e-10 40.3 0.0 1.3e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCL99946.1 - 5.2e-06 26.7 0.1 0.27 11.6 0.0 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCL99946.1 - 2.5e-05 23.3 1.7 0.15 10.9 0.1 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCL99946.1 - 4.6e-05 23.3 0.0 0.0002 21.3 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCL99946.1 - 5.9e-05 22.8 2.6 0.1 12.3 0.1 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CCL99946.1 - 8e-05 21.8 0.0 0.00061 18.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain SnoaL_2 PF12680.2 CCL99946.1 - 0.00059 20.1 1.4 0.0014 18.9 0.1 2.3 2 1 0 2 2 2 1 SnoaL-like domain SnoaL_3 PF13474.1 CCL99946.1 - 0.001 19.0 0.1 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain FAD_binding_2 PF00890.19 CCL99946.1 - 0.0044 15.9 0.5 0.011 14.6 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 CCL99946.1 - 0.029 13.5 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 CCL99946.1 - 0.046 12.7 0.3 0.3 10.0 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 CCL99946.1 - 0.059 11.8 0.1 0.13 10.6 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein p450 PF00067.17 CCL99947.1 - 1.4e-65 221.6 0.0 9e-65 218.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 HA2 PF04408.18 CCL99949.1 - 1.4e-26 92.4 0.9 4.1e-26 90.9 0.0 2.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCL99949.1 - 8.4e-23 80.3 0.0 3.3e-22 78.4 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCL99949.1 - 9.5e-13 47.8 0.0 2.3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCL99949.1 - 5.2e-08 32.5 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCL99949.1 - 2.5e-06 27.6 0.0 5.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCL99949.1 - 0.0018 17.2 0.0 0.004 16.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 CCL99949.1 - 0.0019 18.0 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CCL99949.1 - 0.0041 16.1 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 CCL99949.1 - 0.011 15.6 0.1 0.08 12.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 CCL99949.1 - 0.015 14.3 0.1 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 CCL99949.1 - 0.019 14.6 0.1 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase SRP54 PF00448.17 CCL99949.1 - 0.028 13.8 0.1 0.075 12.4 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 CCL99949.1 - 0.029 14.7 0.4 0.44 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCL99949.1 - 0.054 12.9 0.1 5.9 6.2 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain NACHT PF05729.7 CCL99949.1 - 0.059 13.0 0.1 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 CCL99949.1 - 0.098 12.9 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 CCL99949.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Miro PF08477.8 CCL99949.1 - 0.13 12.7 0.1 0.39 11.2 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein CLTH PF10607.4 CCL99950.1 - 1.2e-20 73.6 0.0 4.6e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 CCL99950.1 - 1e-19 70.8 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 CCL99950.1 - 0.025 14.3 0.2 0.071 12.9 0.0 1.8 2 0 0 2 2 2 0 LisH p450 PF00067.17 CCL99951.1 - 1.1e-50 172.5 0.0 1.3e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCL99952.1 - 9.2e-73 245.3 0.0 1e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 CCL99953.1 - 7e-23 81.0 0.0 1.1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCL99953.1 - 2e-07 30.3 0.0 2.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCL99953.1 - 0.0021 17.1 0.1 0.0033 16.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CCL99953.1 - 0.0082 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CCL99953.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family p450 PF00067.17 CCL99955.1 - 1.3e-75 254.7 0.0 1.5e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 CCL99955.1 - 0.072 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Reticulon p450 PF00067.17 CCL99956.1 - 1.6e-29 102.7 0.0 1.8e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.18 CCL99957.1 - 0.0001 22.1 0.2 0.00021 21.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCL99957.1 - 0.081 11.9 0.2 0.22 10.5 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCL99957.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Nfu_N PF08712.6 CCL99958.1 - 7.3e-31 105.6 0.0 1.3e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CCL99958.1 - 8e-22 76.7 0.1 1.5e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain ABC_tran PF00005.22 CCL99959.1 - 6.3e-26 91.3 0.0 1.7e-25 89.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCL99959.1 - 1.1e-12 48.5 0.1 5.7e-11 42.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CCL99959.1 - 2.4e-08 33.4 0.0 0.0032 16.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CCL99959.1 - 1.1e-06 28.0 0.1 0.046 12.9 0.3 2.7 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCL99959.1 - 4.4e-05 23.8 0.0 7.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCL99959.1 - 0.0011 18.4 0.1 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CCL99959.1 - 0.0024 17.0 0.0 0.009 15.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCL99959.1 - 0.0033 18.2 0.0 0.0086 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCL99959.1 - 0.0035 17.0 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CCL99959.1 - 0.014 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 CCL99959.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCL99959.1 - 0.02 13.9 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 CCL99959.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 CCL99959.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 CCL99959.1 - 0.18 10.2 0.0 0.27 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.21 CCL99961.1 - 3.3e-13 49.2 0.0 4.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCL99961.1 - 0.076 12.9 0.0 0.086 12.7 0.0 1.3 1 1 0 1 1 1 0 RWD domain Porphobil_deam PF01379.15 CCL99962.1 - 3.5e-65 218.9 0.0 4.7e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CCL99962.1 - 1.3e-18 66.8 0.2 2.5e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain UMP1 PF05348.6 CCL99963.1 - 2.2e-21 76.1 0.5 2.8e-21 75.8 0.3 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Glyco_trans_1_4 PF13692.1 CCL99964.1 - 8.3e-20 71.3 0.0 3.4e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCL99964.1 - 3.7e-07 30.4 4.5 4e-07 30.2 0.3 2.8 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain O-FucT PF10250.4 CCL99964.1 - 0.00069 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_trans_1_2 PF13524.1 CCL99964.1 - 0.00079 19.6 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CCL99964.1 - 0.0012 18.2 0.0 0.0053 16.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_11 PF01531.11 CCL99964.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 PARP PF00644.15 CCL99965.1 - 5.1e-50 169.7 2.8 1.5e-49 168.2 0.0 2.4 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 CCL99965.1 - 7e-35 119.5 0.0 1.1e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 CCL99965.1 - 1.4e-19 69.8 0.1 1.4e-19 69.8 0.1 2.5 3 0 0 3 3 3 1 WGR domain Fasciclin PF02469.17 CCL99966.1 - 7.8e-25 87.3 3.2 2.2e-16 60.0 0.2 2.5 2 0 0 2 2 2 2 Fasciclin domain Pentapeptide_2 PF01469.13 CCL99966.1 - 1.8 8.2 26.5 0.095 12.3 2.7 3.2 2 1 1 3 3 3 0 Pentapeptide repeats (8 copies) Prp19_bind PF06991.6 CCL99967.1 - 1.2e-67 228.1 31.8 1.2e-67 228.1 22.1 3.1 2 2 2 4 4 4 1 Splicing factor, Prp19-binding domain zf-CCHC PF00098.18 CCL99967.1 - 0.67 9.9 2.5 1.8 8.6 1.8 1.7 1 1 0 1 1 1 0 Zinc knuckle Pyridox_oxidase PF01243.15 CCL99968.1 - 2.5e-05 24.2 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 CCL99969.1 - 0.00061 19.7 0.0 0.0014 18.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1573 PF07610.6 CCL99969.1 - 0.059 12.9 0.2 5.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) Pyridox_oxidase PF01243.15 CCL99970.1 - 1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 CCL99971.1 - 0.0001 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DEAD PF00270.24 CCL99972.1 - 5.7e-18 64.9 0.0 8.6e-16 57.8 0.0 2.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCL99972.1 - 3.1e-09 36.5 0.0 6.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCL99972.1 - 0.00086 19.1 0.0 0.0023 17.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ECH PF00378.15 CCL99973.1 - 4.8e-39 133.9 0.0 6.5e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CCL99973.1 - 0.0099 16.0 0.2 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_C54 PF03416.14 CCL99974.1 - 6.4e-84 281.3 0.0 3.1e-83 279.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase family C54 Ras PF00071.17 CCL99975.1 - 4e-38 130.3 0.0 1e-36 125.7 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CCL99975.1 - 1.4e-15 57.8 0.0 3.2e-15 56.6 0.0 1.6 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CCL99975.1 - 4.3e-10 39.1 0.0 1.2e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCL99975.1 - 2.1e-06 27.0 0.0 3.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCL99975.1 - 7.9e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCL99975.1 - 2.9e-05 23.6 0.0 0.00019 20.9 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCL99975.1 - 0.013 14.6 0.1 0.031 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCL99975.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CCL99975.1 - 0.037 13.6 0.4 0.094 12.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCL99975.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRPRB PF09439.5 CCL99975.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.14 CCL99975.1 - 0.18 11.2 0.1 16 4.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CCL99975.1 - 0.19 11.1 0.0 0.62 9.5 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3128 PF11326.3 CCL99976.1 - 1.6e-20 72.9 0.2 2.2e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) CHCH PF06747.8 CCL99976.1 - 0.049 13.5 1.1 6 6.9 0.0 2.4 2 0 0 2 2 2 0 CHCH domain Pyr_redox_3 PF13738.1 CCL99977.1 - 6.9e-24 85.0 0.0 1.8e-23 83.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCL99977.1 - 2.6e-20 72.1 0.1 1.2e-14 53.4 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CCL99977.1 - 1.2e-11 44.1 0.1 2.3e-07 30.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCL99977.1 - 2.2e-10 40.7 0.0 3e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCL99977.1 - 3.6e-10 40.1 0.1 0.0057 17.0 0.0 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCL99977.1 - 8.6e-06 25.6 0.0 0.001 19.0 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCL99977.1 - 4.5e-05 22.6 0.0 0.0015 17.6 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 CCL99977.1 - 6.6e-05 21.9 1.6 0.42 9.4 0.0 3.4 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCL99977.1 - 0.00054 19.7 2.0 0.95 9.2 0.1 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 CCL99977.1 - 0.0023 17.1 0.0 0.38 9.8 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 CCL99977.1 - 0.0026 16.2 0.0 0.28 9.5 0.0 3.3 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 CCL99977.1 - 0.0047 16.0 0.0 3.2 6.7 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 CCL99977.1 - 0.0061 15.4 0.0 0.14 10.9 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 CCL99977.1 - 0.018 13.9 0.0 0.089 11.6 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CCL99977.1 - 0.051 13.2 0.0 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxysterol_BP PF01237.13 CCL99978.1 - 3.9e-119 397.2 0.1 1.3e-118 395.5 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 CCL99978.1 - 1.3e-15 57.4 0.1 3.9e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCL99978.1 - 2.1e-14 52.5 2.7 0.0018 17.9 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CCL99978.1 - 2.6e-14 52.9 2.8 3.6e-07 30.1 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCL99978.1 - 6.8e-13 48.7 0.8 8.6e-06 26.1 0.3 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCL99978.1 - 1.5e-11 43.3 1.0 0.013 15.6 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 CCL99978.1 - 5.5e-10 39.3 0.0 6.7e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 CCL99978.1 - 6.8e-09 35.6 1.2 1.1e-08 34.9 0.2 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 CCL99978.1 - 8.2e-06 26.0 0.3 3.2e-05 24.1 0.2 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain Cpn60_TCP1 PF00118.19 CCL99979.1 - 6.5e-138 460.3 11.4 7.4e-138 460.1 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3599 PF12206.3 CCL99979.1 - 0.054 13.7 0.2 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3599) DUF3808 PF10300.4 CCL99980.1 - 2.9e-78 263.5 0.0 4.5e-78 262.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 CCL99980.1 - 1.7e-06 28.2 0.4 0.0044 17.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCL99980.1 - 5.2e-06 26.0 5.7 0.00019 21.0 0.3 4.2 5 0 0 5 5 5 1 TPR repeat Apc3 PF12895.2 CCL99980.1 - 1.1e-05 25.4 2.5 2.8e-05 24.1 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CCL99980.1 - 0.00027 20.4 1.1 0.42 10.3 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCL99980.1 - 0.0018 18.8 0.7 0.017 15.7 0.1 4.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCL99980.1 - 0.0025 17.5 14.3 0.11 12.4 0.3 5.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCL99980.1 - 0.022 14.5 5.8 4.6 7.2 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCL99980.1 - 0.043 13.6 3.5 0.11 12.3 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCL99980.1 - 0.044 13.7 11.0 1.9 8.4 0.2 5.6 6 1 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCL99980.1 - 1.6 9.3 8.8 5.7 7.6 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat CoaE PF01121.15 CCL99981.1 - 3.4e-64 215.5 0.0 4.1e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 CCL99981.1 - 1e-07 32.2 0.1 5.6e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCL99981.1 - 1.4e-06 29.0 0.0 6.4e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCL99981.1 - 0.0011 18.8 0.1 0.0092 15.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCL99981.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.10 CCL99983.1 - 0.14 10.0 1.7 0.15 9.9 1.2 1.0 1 0 0 1 1 1 0 Origin of replication binding protein LSM14 PF12701.2 CCL99984.1 - 1.1e-27 95.7 0.0 2.1e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 CCL99984.1 - 2.1e-10 41.0 0.3 5.3e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 CCL99984.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain PAT1 PF09770.4 CCL99984.1 - 0.21 9.7 18.4 0.31 9.2 12.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CCL99984.1 - 0.35 10.7 6.7 0.43 10.4 4.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med13_C PF06333.7 CCL99984.1 - 3.2 6.1 5.8 4.3 5.7 4.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DUF4349 PF14257.1 CCL99984.1 - 3.6 6.7 8.8 5.8 6.0 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Arrestin_C PF02752.17 CCL99985.1 - 4.9e-11 42.8 0.0 2.5e-08 34.0 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCL99985.1 - 1.6e-06 28.0 0.0 7.1e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CCL99985.1 - 3.6e-05 23.3 0.0 0.00012 21.6 0.0 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like HSF_DNA-bind PF00447.12 CCL99986.1 - 3.4e-35 120.3 0.1 6.1e-35 119.5 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding COG6 PF06419.6 CCL99987.1 - 2.2e-142 475.3 0.0 3.1e-142 474.8 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Med9 PF07544.8 CCL99987.1 - 0.028 14.1 0.2 0.095 12.4 0.1 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Coa1 PF08695.5 CCL99988.1 - 7.7e-31 106.0 0.0 9.6e-31 105.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 E1_dh PF00676.15 CCL99989.1 - 7.4e-111 369.6 0.0 8.8e-111 369.4 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 CCL99989.1 - 0.00025 20.6 1.1 0.00052 19.6 0.7 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 CCL99989.1 - 0.0021 17.0 0.0 0.0033 16.3 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.16 CCL99989.1 - 0.15 10.8 0.5 0.28 9.9 0.0 1.7 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain DUF77 PF01910.12 CCL99990.1 - 1.6e-24 85.4 0.0 4.6e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF77 Arm PF00514.18 CCL99991.1 - 1.6e-12 46.7 10.4 1.1e-05 25.0 0.0 5.9 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCL99991.1 - 1.2e-10 41.5 11.7 0.0016 18.6 0.2 7.4 3 2 5 8 8 8 2 HEAT repeats Cnd1 PF12717.2 CCL99991.1 - 6.4e-06 26.1 0.4 0.051 13.4 0.1 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCL99991.1 - 7.1e-06 25.6 22.8 0.41 10.8 0.0 8.8 10 0 0 10 10 10 2 HEAT repeat Adaptin_N PF01602.15 CCL99991.1 - 0.00016 20.1 1.5 0.26 9.5 0.2 3.6 2 1 1 4 4 4 2 Adaptin N terminal region Atx10homo_assoc PF09759.4 CCL99991.1 - 0.004 16.8 0.3 3 7.6 0.1 4.0 4 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 CCL99991.1 - 0.006 17.0 18.1 0.067 13.7 0.0 7.0 8 1 1 9 9 9 1 HEAT-like repeat Proteasom_PSMB PF10508.4 CCL99991.1 - 0.01 14.1 0.4 0.53 8.4 0.2 2.7 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 CCL99991.1 - 0.036 13.4 0.0 0.19 11.0 0.0 2.3 2 0 0 2 2 2 0 CLASP N terminal DNA_methylase PF00145.12 CCL99992.1 - 3.8e-41 141.3 0.0 1.3e-40 139.5 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 CCL99992.1 - 9.6e-05 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 BAH domain MCM PF00493.18 CCL99994.1 - 5.7e-135 449.3 0.0 3.1e-134 446.9 0.0 1.9 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CCL99994.1 - 1.7e-27 96.3 0.6 1.7e-27 96.3 0.4 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 CCL99994.1 - 3.6e-08 33.2 0.0 9.3e-07 28.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCL99994.1 - 1.3e-07 31.0 0.1 1e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 CCL99994.1 - 0.00049 20.4 0.1 0.0021 18.4 0.1 2.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCL99994.1 - 0.026 14.1 0.0 0.084 12.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCL99994.1 - 0.073 12.5 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Peptidase_S8 PF00082.17 CCL99995.1 - 1.8e-50 171.7 2.4 1.8e-50 171.7 1.6 1.6 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 CCL99995.1 - 8e-28 96.0 0.5 1.6e-27 95.1 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Herpes_gE PF02480.11 CCL99995.1 - 0.019 13.2 0.0 0.033 12.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E POT1 PF02765.12 CCL99996.1 - 9e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 zinc_ribbon_2 PF13240.1 CCL99996.1 - 0.041 13.3 1.0 0.1 12.1 0.7 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 CCL99996.1 - 0.054 13.3 0.5 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon Ly49 PF08391.5 CCL99996.1 - 2.5 8.2 6.0 6.5 6.9 0.6 3.1 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region TAP42 PF04177.7 CCL99997.1 - 1.9e-65 221.0 0.6 2.2e-65 220.8 0.4 1.0 1 0 0 1 1 1 1 TAP42-like family Ras PF00071.17 CCL99998.1 - 2.9e-58 195.8 0.4 3.5e-58 195.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCL99998.1 - 1.6e-21 77.0 0.0 3.3e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCL99998.1 - 1.5e-15 56.9 0.1 1.9e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCL99998.1 - 2.2e-07 30.4 0.2 1.5e-06 27.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCL99998.1 - 2.7e-07 29.9 0.5 3.3e-07 29.6 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCL99998.1 - 1.2e-05 25.2 0.1 2.4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCL99998.1 - 1.2e-05 24.6 0.1 5.1e-05 22.5 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CCL99998.1 - 0.0012 18.1 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 CCL99998.1 - 0.0045 16.8 0.1 0.95 9.2 0.0 2.6 2 1 0 3 3 3 1 Dynamin family CPT PF07931.7 CCL99998.1 - 0.0069 16.0 0.0 0.059 12.9 0.0 2.3 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.4 CCL99998.1 - 0.011 15.1 0.8 0.11 11.9 0.6 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 CCL99998.1 - 0.043 13.5 0.0 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 CCL99998.1 - 0.047 13.8 0.0 1.6 8.8 0.0 2.5 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 CCL99998.1 - 0.052 13.2 0.2 6.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCL99998.1 - 0.11 12.4 0.3 0.35 10.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain MTHFR PF02219.12 CCL99999.1 - 2.7e-107 358.1 0.0 3.9e-107 357.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TMP-TENI PF02581.12 CCL99999.1 - 0.041 13.0 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI EPL1 PF10513.4 CCM00001.1 - 6.2e-18 65.5 0.4 6.2e-18 65.5 0.3 2.9 3 0 0 3 3 3 1 Enhancer of polycomb-like WD40 PF00400.27 CCM00002.1 - 0.0055 16.5 0.2 0.019 14.8 0.1 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Transket_pyr PF02779.19 CCM00003.1 - 1e-38 132.5 0.1 1.7e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCM00003.1 - 6e-22 77.8 0.0 2.3e-21 75.9 0.0 2.1 1 0 0 1 1 1 1 Transketolase, C-terminal domain PI3Ka PF00613.15 CCM00003.1 - 9.8e-20 70.5 0.0 2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CCM00003.1 - 2.9e-15 56.3 0.0 4.9e-09 36.0 0.0 2.9 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase RdRP PF05183.7 CCM00004.1 - 1.5e-161 539.0 0.0 2e-161 538.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Peptidase_M28 PF04389.12 CCM00004.1 - 1.5e-34 119.2 0.7 6e-33 114.0 0.0 2.4 2 0 0 2 2 2 2 Peptidase family M28 DUF2476 PF10630.4 CCM00005.1 - 0.062 13.1 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2476) Sybindin PF04099.7 CCM00006.1 - 5.7e-40 136.3 0.0 6.2e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CCM00006.1 - 1.6e-08 34.4 0.0 1.6e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region HORMA PF02301.13 CCM00007.1 - 2e-44 151.5 0.0 3.6e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PFU PF09070.6 CCM00008.1 - 5.9e-43 145.5 0.1 1.1e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 CCM00008.1 - 1.5e-37 126.0 16.1 9.7e-09 34.7 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PUL PF08324.6 CCM00008.1 - 1e-29 103.1 0.7 1.4e-29 102.7 0.5 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 CCM00008.1 - 7e-05 22.5 0.0 0.079 12.7 0.0 2.8 1 1 2 3 3 3 2 Ciliary BBSome complex subunit 2, middle region IpaD PF06511.6 CCM00008.1 - 0.044 12.7 0.0 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 Invasion plasmid antigen IpaD DUF2587 PF10759.4 CCM00008.1 - 0.15 11.4 0.0 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) His_Phos_1 PF00300.17 CCM00009.1 - 4e-22 78.9 0.0 2.6e-21 76.3 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyoxal_oxid_N PF07250.6 CCM00010.1 - 3.1e-48 163.9 0.0 8e-48 162.6 0.0 1.7 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CCM00010.1 - 4e-19 68.5 0.1 3.7e-18 65.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 CCM00010.1 - 0.11 12.3 4.6 10 5.9 0.1 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain KH_1 PF00013.24 CCM00011.1 - 0.00018 21.0 0.7 0.00018 21.0 0.5 1.8 2 0 0 2 2 2 1 KH domain DUF3835 PF12927.2 CCM00012.1 - 0.14 13.1 0.4 0.23 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) Glyco_transf_22 PF03901.12 CCM00013.1 - 5.4e-93 312.2 19.7 6.9e-93 311.9 13.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family F-box-like PF12937.2 CCM00014.1 - 0.0028 17.3 5.5 0.034 13.8 3.8 2.6 1 1 0 1 1 1 1 F-box-like DUF1713 PF08213.6 CCM00015.1 - 9.6e-08 31.5 22.3 1.4e-07 30.9 15.4 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) gag-asp_proteas PF13975.1 CCM00016.1 - 0.0077 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Ribosomal_L32e PF01655.13 CCM00016.1 - 0.07 13.1 0.2 5.1 7.1 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein L32 Ribosomal_L7Ae PF01248.21 CCM00017.1 - 1.3e-11 43.8 0.1 1.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCM00017.1 - 0.019 14.7 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 UQ_con PF00179.21 CCM00018.1 - 4.7e-45 152.4 0.1 5.2e-45 152.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCM00018.1 - 1.6e-05 24.7 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCM00018.1 - 0.081 12.8 0.8 0.12 12.2 0.6 1.6 1 1 0 1 1 1 0 RWD domain Methyltransf_31 PF13847.1 CCM00019.1 - 4.3e-07 29.6 0.0 8.3e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM00019.1 - 4.4e-07 29.7 0.0 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM00019.1 - 3.3e-06 27.4 0.0 6.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM00019.1 - 5.3e-06 26.8 0.0 8.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 CCM00019.1 - 0.0017 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.11 CCM00019.1 - 0.019 13.2 0.0 0.028 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 CCM00019.1 - 0.057 13.9 0.0 0.53 10.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.21 CCM00020.1 - 4.6e-53 179.3 0.1 5.7e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Syja_N PF02383.13 CCM00021.1 - 6.1e-87 291.3 0.0 8.7e-87 290.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 CCM00021.1 - 5.1e-28 96.7 0.0 1.1e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase Cofilin_ADF PF00241.15 CCM00021.1 - 0.011 15.6 0.1 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Myosin_TH1 PF06017.8 CCM00021.1 - 0.041 13.1 0.1 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Myosin tail zf-DHHC PF01529.15 CCM00022.1 - 2.4e-14 53.1 3.8 1.7e-10 40.5 0.1 2.3 1 1 1 2 2 2 2 DHHC palmitoyltransferase Amidase PF01425.16 CCM00023.1 - 1.3e-93 314.2 0.0 1.9e-93 313.7 0.0 1.3 1 0 0 1 1 1 1 Amidase DUF953 PF06110.6 CCM00024.1 - 3.2e-19 68.5 0.0 3.8e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) LamB_YcsF PF03746.11 CCM00025.1 - 0.19 10.7 5.6 1.7 7.6 0.2 2.8 1 1 2 3 3 3 0 LamB/YcsF family Mito_carr PF00153.22 CCM00026.1 - 6.2e-65 214.9 0.1 2.2e-25 88.2 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 CCM00026.1 - 2.4e-17 60.8 3.9 1.9e-05 23.6 0.1 6.3 7 0 0 7 7 7 3 EF hand EF-hand_7 PF13499.1 CCM00026.1 - 3.2e-17 62.4 2.9 4.8e-07 29.8 0.2 4.6 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CCM00026.1 - 5.4e-17 60.0 3.0 6.4e-05 22.5 0.1 5.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CCM00026.1 - 6.8e-11 41.6 3.2 0.0083 15.7 0.1 5.8 5 1 1 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.1 CCM00026.1 - 8.8e-08 31.1 6.6 0.00059 19.0 0.1 4.1 4 0 0 4 4 4 2 EF hand Met_10 PF02475.11 CCM00027.1 - 5.6e-62 208.8 0.0 8.2e-62 208.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CCM00027.1 - 0.0027 17.7 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00027.1 - 0.0053 17.3 0.0 0.018 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MethyltransfD12 PF02086.10 CCM00027.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.11 CCM00027.1 - 0.082 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase TatD_DNase PF01026.16 CCM00028.1 - 5.4e-21 74.9 0.0 8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase V-SNARE_C PF12352.3 CCM00029.1 - 6.5e-15 54.9 4.5 8.6e-15 54.5 0.4 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Laminin_I PF06008.9 CCM00029.1 - 0.0013 18.1 0.4 0.005 16.1 0.3 1.8 2 0 0 2 2 2 1 Laminin Domain I Occludin_ELL PF07303.8 CCM00029.1 - 0.0027 18.3 0.3 0.022 15.5 0.2 2.4 2 1 1 3 3 2 1 Occludin homology domain Laminin_II PF06009.7 CCM00029.1 - 0.024 14.3 2.5 0.19 11.4 0.1 2.6 2 1 1 3 3 3 0 Laminin Domain II TBPIP PF07106.8 CCM00029.1 - 0.043 13.3 0.7 0.11 12.0 0.5 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spectrin PF00435.16 CCM00029.1 - 0.051 13.8 1.9 0.52 10.6 1.1 2.3 1 1 1 2 2 2 0 Spectrin repeat AAA_13 PF13166.1 CCM00029.1 - 0.059 11.8 0.5 0.099 11.0 0.2 1.3 1 1 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 CCM00029.1 - 0.065 12.9 3.6 0.11 12.2 2.0 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ada3 PF10198.4 CCM00029.1 - 0.066 12.9 3.6 0.088 12.5 1.3 1.8 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 GrpE PF01025.14 CCM00029.1 - 0.067 12.7 1.8 0.12 11.9 1.2 1.5 1 1 0 1 1 1 0 GrpE FlgN PF05130.7 CCM00029.1 - 0.076 13.2 1.7 0.14 12.3 1.2 1.5 1 1 0 1 1 1 0 FlgN protein CK2S PF15011.1 CCM00029.1 - 0.076 12.7 0.5 0.25 11.1 0.3 2.0 1 1 1 2 2 2 0 Casein Kinase 2 substrate DUF2299 PF10061.4 CCM00029.1 - 0.08 12.3 0.3 7.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2299) Mid2 PF04478.7 CCM00029.1 - 0.089 12.2 1.1 0.15 11.4 0.7 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syntaxin PF00804.20 CCM00029.1 - 0.11 12.6 0.8 0.3 11.2 0.3 1.9 1 1 2 3 3 3 0 Syntaxin DUF2664 PF10867.3 CCM00029.1 - 0.12 13.0 0.2 0.12 13.0 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2664) TipAS PF07739.8 CCM00029.1 - 0.13 12.6 0.4 0.28 11.5 0.2 1.7 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Tropomyosin_1 PF12718.2 CCM00029.1 - 0.15 11.8 1.6 0.44 10.3 0.4 1.7 1 1 1 2 2 2 0 Tropomyosin like WXG100 PF06013.7 CCM00029.1 - 0.15 12.0 1.3 5.6 7.0 0.0 3.1 2 1 1 3 3 3 0 Proteins of 100 residues with WXG FUSC PF04632.7 CCM00029.1 - 0.23 9.8 3.6 0.3 9.4 2.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.7 CCM00029.1 - 0.57 10.0 4.9 0.54 10.0 0.7 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.13 CCM00029.1 - 2.4 7.1 5.2 3.8 6.4 3.2 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 CCM00030.1 - 0.3 9.6 3.6 0.36 9.3 2.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Clostridium_P47 PF06597.6 CCM00030.1 - 0.48 8.8 7.0 0.61 8.5 4.9 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein Proteasome PF00227.21 CCM00032.1 - 4.6e-24 84.7 0.0 6.7e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Mid2 PF04478.7 CCM00033.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2407_C PF13373.1 CCM00033.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain JmjC PF02373.17 CCM00034.1 - 1.5e-37 128.2 0.1 2.8e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CCM00034.1 - 1.1e-15 56.8 0.1 2e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 CCM00034.1 - 4.3e-13 49.2 0.9 1e-12 48.0 0.6 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CCM00034.1 - 3.4e-11 43.0 0.5 9.3e-11 41.7 0.3 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain FHA PF00498.21 CCM00035.1 - 5.1e-05 23.3 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain CAP59_mtransfer PF11735.3 CCM00036.1 - 1.7e-44 151.8 0.0 2.7e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF843 PF05814.6 CCM00036.1 - 0.026 14.3 0.6 0.061 13.1 0.4 1.5 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) DUF4131 PF13567.1 CCM00036.1 - 0.085 12.2 0.3 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Stb3 PF10330.4 CCM00036.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative Sin3 binding protein OTCace_N PF02729.16 CCM00037.1 - 8.5e-45 151.9 0.0 1.2e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 CCM00037.1 - 1.2e-39 135.7 0.0 1.6e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Glycogen_syn PF05693.8 CCM00038.1 - 0 1084.1 0.0 0 1083.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CCM00038.1 - 7.4e-08 31.9 0.0 0.00033 20.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CCM00038.1 - 1.7e-07 30.9 1.3 2.2e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 CCM00038.1 - 3.8e-06 27.1 0.1 7.6e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Aldo_ket_red PF00248.16 CCM00039.1 - 1.6e-46 158.4 0.0 2.2e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 CCM00040.1 - 1.6e-13 49.9 0.0 0.00061 19.5 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.2 CCM00040.1 - 1.7e-05 24.4 1.4 0.00025 20.7 0.0 2.4 2 0 0 2 2 2 1 F-box-like PQQ_2 PF13360.1 CCM00040.1 - 0.00058 19.4 0.8 0.24 10.8 0.1 3.5 3 1 1 4 4 4 2 PQQ-like domain F-box PF00646.28 CCM00040.1 - 0.016 14.8 0.3 0.096 12.3 0.0 2.1 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.2 CCM00041.1 - 0.02 15.2 0.0 0.12 12.7 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 CCM00041.1 - 0.024 14.4 0.8 0.11 12.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 CCM00041.1 - 0.04 14.1 0.3 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.19 CCM00041.1 - 0.047 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ank_3 PF13606.1 CCM00041.1 - 0.094 13.0 0.3 0.99 9.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.1 CCM00041.1 - 0.13 12.7 0.0 0.51 10.9 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) HET PF06985.6 CCM00042.1 - 4.9e-17 62.3 1.9 1.6e-13 50.9 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CHAT PF12770.2 CCM00043.1 - 2.5e-34 118.7 0.1 5.4e-34 117.6 0.0 1.6 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 CCM00043.1 - 4.4e-10 39.3 0.0 0.76 9.7 0.0 5.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCM00043.1 - 0.023 14.8 0.7 12 6.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3745 PF12560.3 CCM00043.1 - 0.18 11.4 0.0 1.7e+02 1.9 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3745) GTP_cyclohydro2 PF00925.15 CCM00044.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II Pkinase PF00069.20 CCM00045.1 - 1e-68 231.3 0.0 1.4e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00045.1 - 1.9e-29 102.5 0.0 2.7e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCM00045.1 - 0.00097 18.2 0.0 0.0025 16.9 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM00045.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCM00045.1 - 0.026 13.4 0.0 0.062 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CCM00045.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family NAD_binding_1 PF00175.16 CCM00046.1 - 1e-27 96.8 0.0 1.6e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCM00046.1 - 3.1e-16 59.2 0.0 1.4e-15 57.2 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CCM00046.1 - 2.3e-07 30.8 0.0 6.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF4101 PF13355.1 CCM00046.1 - 0.075 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4101) CPSase_L_D2 PF02786.12 CCM00047.1 - 1.2e-69 233.8 0.0 2.3e-69 232.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CCM00047.1 - 1.2e-44 150.8 0.1 3e-44 149.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCM00047.1 - 4.3e-33 113.5 0.0 1.9e-32 111.4 0.0 2.1 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CCM00047.1 - 1.3e-16 59.9 5.6 2.7e-16 58.9 3.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CCM00047.1 - 1.8e-12 47.4 0.1 4.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCM00047.1 - 1.4e-09 37.1 0.1 5.5e-05 22.0 0.0 2.6 1 1 1 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CCM00047.1 - 6.1e-09 35.4 1.5 6.7e-08 32.0 0.4 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CCM00047.1 - 4.1e-08 32.8 0.0 1.2e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CCM00047.1 - 1.1e-07 31.4 0.0 3.2e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.1 CCM00047.1 - 0.0005 20.3 0.4 0.49 10.7 0.1 2.6 2 0 0 2 2 2 2 HlyD family secretion protein PYNP_C PF07831.8 CCM00047.1 - 0.044 13.2 1.3 0.12 11.8 0.4 2.1 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD PF00529.15 CCM00047.1 - 0.054 12.8 2.5 0.14 11.4 0.8 2.0 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 CCM00047.1 - 0.099 12.3 0.3 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein ATP-grasp_3 PF02655.9 CCM00047.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain DUF2118 PF09891.4 CCM00047.1 - 0.11 12.2 1.5 0.34 10.6 0.7 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) DUF989 PF06181.6 CCM00047.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF989) Legionella_OMP PF05150.7 CCM00048.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor UCH PF00443.24 CCM00049.1 - 8.4e-43 146.4 0.0 2.5e-42 144.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CCM00049.1 - 5.3e-24 83.3 0.4 1.5e-17 62.7 0.1 2.6 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.1 CCM00049.1 - 1.1e-11 44.6 3.3 8.3e-07 28.7 0.4 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3425 PF11905.3 CCM00050.1 - 0.035 13.9 0.1 2.5 7.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3425) TPR_12 PF13424.1 CCM00051.1 - 0.03 14.2 0.0 2.1 8.3 0.0 3.2 2 2 2 4 4 4 0 Tetratricopeptide repeat DUF3292 PF11696.3 CCM00052.1 - 1.2e-196 654.4 0.0 1.6e-196 654.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) DUF639 PF04842.7 CCM00052.1 - 0.011 13.9 0.2 0.017 13.3 0.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) PRT_C PF08372.5 CCM00052.1 - 0.013 14.9 0.1 0.043 13.3 0.0 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Sel1 PF08238.7 CCM00053.1 - 1.6e-45 152.5 19.1 2.8e-08 34.1 0.2 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_5 PF12688.2 CCM00053.1 - 0.057 13.4 0.1 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Tetratrico peptide repeat ADH_zinc_N PF00107.21 CCM00054.1 - 1.1e-25 89.6 0.2 1.6e-25 89.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM00054.1 - 1.4e-15 58.2 0.0 2.7e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM00054.1 - 3.5e-13 49.2 0.1 9.5e-13 47.8 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 CCM00054.1 - 0.038 13.5 0.1 0.056 13.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase BAG PF02179.11 CCM00055.1 - 3e-12 46.4 0.0 5.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 CCM00055.1 - 1.2e-09 37.3 0.0 2.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.20 CCM00056.1 - 2.8e-53 180.7 0.0 3.7e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00056.1 - 3.3e-37 127.9 0.0 4.7e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM00056.1 - 2.1e-08 33.5 0.0 3.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCM00056.1 - 0.0017 18.1 0.0 0.22 11.1 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCM00056.1 - 0.21 10.4 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Got1 PF04178.7 CCM00057.1 - 3.1e-20 72.4 11.8 3.7e-20 72.2 8.2 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 CCM00057.1 - 0.0021 17.0 5.0 0.0026 16.8 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) DUF308 PF03729.8 CCM00057.1 - 1.8 8.6 17.3 0.39 10.7 3.0 2.3 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) zf-TRAF PF02176.13 CCM00058.1 - 0.0037 17.6 3.3 0.054 13.8 2.0 2.2 1 1 2 3 3 3 3 TRAF-type zinc finger DUF2382 PF09557.5 CCM00058.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) MFS_1 PF07690.11 CCM00059.1 - 2.9e-39 134.8 31.3 2.9e-39 134.8 21.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily tRNA-synt_1 PF00133.17 CCM00060.1 - 5.2e-218 724.9 0.0 2e-217 722.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCM00060.1 - 2.2e-28 98.9 0.1 5.6e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCM00060.1 - 1.4e-16 60.1 0.2 5e-07 28.7 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-C2H2_jaz PF12171.3 CCM00061.1 - 1.4e-07 31.3 0.1 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM00061.1 - 3.1e-06 27.1 0.2 5.8e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 CCM00061.1 - 7.3e-06 25.8 20.8 1.3e-05 25.0 4.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1777) zf-DBF PF07535.7 CCM00061.1 - 0.035 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 DBF zinc finger Bud13 PF09736.4 CCM00061.1 - 0.6 10.3 18.8 0.86 9.8 7.1 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF4140 PF13600.1 CCM00061.1 - 0.66 10.4 11.5 0.32 11.4 3.5 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 CCM00061.1 - 1.3 7.9 13.8 0.87 8.4 1.8 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L11_N PF03946.9 CCM00062.1 - 3e-17 61.8 0.1 5e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCM00062.1 - 2.2e-12 46.9 0.7 3.7e-12 46.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cyclin PF08613.6 CCM00063.1 - 1.1e-16 61.5 0.0 1.6e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin Pkinase PF00069.20 CCM00064.1 - 1.2e-36 126.1 0.0 1.6e-24 86.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00064.1 - 2.3e-17 62.9 0.0 4.2e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM00064.1 - 0.01 14.8 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like U3_assoc_6 PF08640.6 CCM00065.1 - 3.1e-27 94.1 1.6 3.7e-26 90.6 0.5 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 CCM00065.1 - 0.022 15.3 5.1 5.8 7.8 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat F-box-like PF12937.2 CCM00067.1 - 1.2e-05 24.9 0.0 3.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM00067.1 - 1.6e-05 24.4 0.0 4.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain FYVE PF01363.16 CCM00067.1 - 6.1 6.8 7.4 0.74 9.7 0.5 2.4 2 0 0 2 2 2 0 FYVE zinc finger RNase_H PF00075.19 CCM00068.1 - 1.4e-12 48.1 0.0 2.6e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 RNase H Glyco_transf_22 PF03901.12 CCM00069.1 - 3.8e-38 131.5 16.3 5e-38 131.1 11.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ABC2_membrane PF01061.19 CCM00070.1 - 2.9e-32 111.5 20.5 5.4e-32 110.6 14.2 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CCM00070.1 - 5e-29 101.3 0.0 9.3e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCM00070.1 - 1e-08 35.5 0.1 1.5e-07 31.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CCM00070.1 - 0.0009 18.4 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCM00070.1 - 0.00097 18.5 0.0 0.09 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCM00070.1 - 0.0015 18.0 0.1 0.0039 16.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 CCM00070.1 - 0.0042 16.3 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain EGF_2 PF07974.8 CCM00070.1 - 0.0065 16.5 11.6 0.0065 16.5 8.0 3.4 3 0 0 3 3 2 2 EGF-like domain AAA_15 PF13175.1 CCM00070.1 - 0.0083 15.2 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.2 CCM00070.1 - 0.0095 15.0 25.3 0.018 14.0 17.6 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein Rad17 PF03215.10 CCM00070.1 - 0.024 13.3 0.0 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCM00070.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCM00070.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CCM00070.1 - 0.08 12.4 0.0 0.4 10.1 0.0 2.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.1 CCM00070.1 - 0.081 13.7 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CCM00070.1 - 0.091 12.6 0.0 0.42 10.5 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 CCM00070.1 - 0.13 10.9 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 CCM00070.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCM00070.1 - 0.25 11.6 0.0 0.49 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain hEGF PF12661.2 CCM00070.1 - 0.45 10.7 28.1 0.05 13.7 1.9 4.8 4 0 0 4 4 4 0 Human growth factor-like EGF FA_hydroxylase PF04116.8 CCM00071.1 - 2.7e-13 50.3 32.7 3.1e-13 50.1 18.3 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily DnaJ PF00226.26 CCM00072.1 - 1.2e-18 66.5 3.3 2.3e-18 65.6 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCM00072.1 - 3.2e-18 65.3 1.3 2.1e-17 62.7 0.1 2.6 3 0 0 3 3 3 1 DnaJ C terminal domain WD40 PF00400.27 CCM00073.1 - 1.3e-19 69.2 7.5 1.3e-07 31.1 0.1 6.1 6 1 0 6 6 6 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCM00073.1 - 0.0012 18.2 0.0 1.9 8.0 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SIR2 PF02146.12 CCM00074.1 - 5.3e-30 104.4 0.0 2.1e-20 73.2 0.0 2.4 2 1 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 CCM00074.1 - 0.059 13.1 0.1 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain BmKX PF09132.5 CCM00074.1 - 0.11 12.3 2.8 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 BmKX WD40 PF00400.27 CCM00075.1 - 3.8e-30 102.6 5.4 1.7e-07 30.8 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCM00075.1 - 0.061 12.8 0.0 0.43 10.1 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DSS1_SEM1 PF05160.8 CCM00076.1 - 7.1e-19 67.3 12.6 1.9e-18 65.9 8.7 1.6 1 1 0 1 1 1 1 DSS1/SEM1 family F-box-like PF12937.2 CCM00077.1 - 0.077 12.7 2.3 0.27 10.9 1.6 1.9 1 0 0 1 1 1 0 F-box-like RP-C_C PF11800.3 CCM00077.1 - 0.16 11.6 0.6 0.6 9.7 0.6 1.8 2 0 0 2 2 2 0 Replication protein C C-terminal region GEMIN8 PF15348.1 CCM00077.1 - 2.7 7.9 14.4 5.4 6.9 10.0 1.5 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 CDC45 PF02724.9 CCM00077.1 - 3.2 5.6 23.1 5 5.0 16.0 1.3 1 0 0 1 1 1 0 CDC45-like protein BAR PF03114.13 CCM00078.1 - 0.082 12.4 6.3 0.03 13.8 1.1 2.5 3 0 0 3 3 3 0 BAR domain Sugar_tr PF00083.19 CCM00079.1 - 2.7e-39 134.9 34.1 1.9e-24 86.0 6.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCM00079.1 - 6.5e-22 77.7 64.2 6.9e-20 71.0 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCM00079.1 - 2.6e-08 32.6 22.0 0.00035 19.0 0.6 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 CCM00079.1 - 0.037 12.5 28.5 0.37 9.2 19.8 2.0 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like Chordopox_A13L PF05961.6 CCM00079.1 - 0.11 12.4 0.4 0.35 10.8 0.3 2.0 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Acetate_kinase PF00871.12 CCM00081.1 - 1.4e-86 290.5 0.0 3e-67 226.8 0.0 2.2 1 1 1 2 2 2 2 Acetokinase family Integrase_1 PF12835.2 CCM00081.1 - 0.11 12.2 0.1 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Integrase XFP_N PF09364.5 CCM00082.1 - 9.3e-155 514.8 0.0 1.2e-154 514.4 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 CCM00082.1 - 4.5e-68 228.3 0.0 6.7e-68 227.7 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 CCM00082.1 - 2.1e-65 219.9 0.0 3.6e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 CCM00082.1 - 0.0016 18.0 0.1 0.0051 16.3 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Abhydrolase_6 PF12697.2 CCM00083.1 - 2.5e-30 106.0 0.1 3.2e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM00083.1 - 3e-20 72.7 1.6 7.6e-14 51.8 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM00083.1 - 5.5e-13 48.8 0.0 7.4e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCM00083.1 - 0.00028 20.6 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 CCM00083.1 - 0.00082 18.7 0.2 0.0034 16.6 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.15 CCM00083.1 - 0.046 13.9 0.2 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain Peptidase_S9 PF00326.16 CCM00083.1 - 0.13 11.4 0.7 0.8 8.8 0.1 2.2 2 1 1 3 3 3 0 Prolyl oligopeptidase family Na_Ca_ex PF01699.19 CCM00084.1 - 4.8e-41 139.6 36.7 2.4e-24 85.4 7.1 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3043 PF11241.3 CCM00084.1 - 0.21 11.1 0.2 0.83 9.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) p450 PF00067.17 CCM00085.1 - 1e-62 212.2 0.0 2.6e-62 210.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 GTP_cyclohydroI PF01227.17 CCM00085.1 - 0.03 13.6 0.1 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I RasGAP PF00616.14 CCM00086.1 - 5.7e-34 117.5 0.0 8.3e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Glyco_transf_41 PF13844.1 CCM00086.1 - 0.04 11.9 0.0 0.055 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 RasGAP PF00616.14 CCM00087.1 - 2e-53 181.0 0.1 1.1e-52 178.5 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 CCM00087.1 - 1.6e-35 121.8 1.4 4.6e-35 120.3 0.1 2.3 2 0 0 2 2 2 1 RasGAP C-terminus Herpes_UL14 PF03580.9 CCM00087.1 - 0.011 15.5 2.3 0.028 14.1 1.6 1.6 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DUF972 PF06156.8 CCM00087.1 - 2.7 8.3 7.6 14 6.0 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) F-box-like PF12937.2 CCM00088.1 - 8e-05 22.2 0.7 8e-05 22.2 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM00088.1 - 0.00013 21.5 0.4 0.0003 20.3 0.3 1.7 1 0 0 1 1 1 1 F-box domain UreE_N PF02814.10 CCM00088.1 - 0.058 12.9 0.0 0.72 9.4 0.0 2.3 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain CTDII PF01556.13 CCM00090.1 - 9.3e-20 70.3 0.0 1.3e-17 63.4 0.0 3.1 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCM00090.1 - 1e-15 57.4 14.3 2.2e-15 56.4 9.9 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CCM00090.1 - 2.9e-05 23.7 2.7 0.071 12.8 0.0 2.7 3 0 0 3 3 3 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 CCM00090.1 - 0.00032 20.9 6.1 0.7 10.2 0.0 3.3 1 1 1 2 2 2 2 Restriction alleviation protein Lar DZR PF12773.2 CCM00090.1 - 0.39 10.5 11.2 3.6 7.4 7.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C4_Topoisom PF01396.14 CCM00090.1 - 3.1 7.3 5.1 21 4.7 0.1 3.2 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Cullin PF00888.17 CCM00091.1 - 1.6e-147 492.6 0.0 2.5e-147 491.9 0.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCM00091.1 - 4.7e-28 96.8 1.2 1.3e-27 95.3 0.8 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Xpo1 PF08389.7 CCM00091.1 - 1.6e-17 63.7 2.6 7e-17 61.7 0.0 3.6 4 0 0 4 4 4 1 Exportin 1-like protein BDHCT PF08072.6 CCM00091.1 - 0.89 9.7 6.1 0.27 11.3 0.5 2.8 3 0 0 3 3 3 0 BDHCT (NUC031) domain Asp PF00026.18 CCM00093.1 - 2.7e-47 161.5 0.2 3.7e-47 161.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease BRO1 PF03097.13 CCM00095.1 - 2.4e-31 108.8 0.0 2.6e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCM00096.1 - 2.2e-66 223.8 12.2 3.4e-66 223.2 8.4 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV SPX PF03105.14 CCM00096.1 - 6.3 6.4 12.4 52 3.4 8.6 2.1 1 1 0 1 1 1 0 SPX domain DUF3421 PF11901.3 CCM00097.1 - 4.4e-18 65.1 0.0 5.2e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) WLM PF08325.5 CCM00098.1 - 4.3e-39 134.3 5.8 9.1e-37 126.7 4.0 2.9 1 1 0 1 1 1 1 WLM domain Peptidase_U32 PF01136.14 CCM00098.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family U32 DUF45 PF01863.12 CCM00098.1 - 0.11 12.2 0.2 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 PFK PF00365.15 CCM00099.1 - 2.7e-159 528.5 3.6 2.3e-95 318.7 0.2 3.1 3 0 0 3 3 3 3 Phosphofructokinase FAM216B PF15107.1 CCM00099.1 - 0.019 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 FAM216B protein family DUF4646 PF15496.1 CCM00099.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) KilA-N PF04383.8 CCM00100.1 - 0.0036 16.9 0.4 0.12 11.9 0.0 2.5 2 1 0 2 2 2 1 KilA-N domain DUF596 PF04591.7 CCM00100.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF596 SOG2 PF10428.4 CCM00100.1 - 0.41 9.2 11.2 0.58 8.7 7.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ketoacyl-synt PF00109.21 CCM00101.1 - 2.2e-74 250.1 0.0 4.9e-74 249.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CCM00101.1 - 4.4e-46 157.6 0.0 1.1e-45 156.4 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 CCM00101.1 - 5.1e-37 126.3 4.5 5.4e-37 126.2 2.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 CCM00101.1 - 2.5e-20 73.6 0.0 9.2e-20 71.8 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 CCM00101.1 - 4e-19 68.8 0.0 1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 CCM00101.1 - 1.9e-16 60.0 1.0 2.9e-07 30.6 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 CCM00101.1 - 7.6e-07 28.9 0.1 0.00024 20.9 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM00101.1 - 3.3e-06 27.1 0.2 3.3e-06 27.1 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 CCM00101.1 - 9.1e-05 21.5 0.1 0.00019 20.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.8 CCM00101.1 - 0.0071 15.9 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CCM00101.1 - 0.01 15.4 0.3 0.03 13.9 0.2 1.7 1 0 0 1 1 1 0 PGAP1-like protein Pcc1 PF09341.5 CCM00102.1 - 1.5e-18 66.5 0.2 2.4e-18 65.9 0.2 1.3 1 0 0 1 1 1 1 Transcription factor Pcc1 Peptidase_M24 PF00557.19 CCM00103.1 - 1e-23 84.0 0.1 1.3e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4316 PF14195.1 CCM00103.1 - 0.44 10.6 6.6 12 6.0 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Methyltransf_11 PF08241.7 CCM00104.1 - 2.1e-11 44.1 0.0 5.9e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM00104.1 - 2.1e-11 44.0 0.0 4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00104.1 - 4.3e-10 40.1 0.0 1.3e-09 38.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM00104.1 - 4.4e-10 39.6 0.0 9.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM00104.1 - 4.7e-08 32.9 0.0 9.4e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM00104.1 - 8.6e-07 28.6 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCM00104.1 - 7.3e-06 25.4 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CCM00104.1 - 9.2e-06 26.0 0.0 0.00019 21.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCM00104.1 - 5.1e-05 22.4 0.0 0.00024 20.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 CCM00104.1 - 0.00013 21.1 0.0 0.00079 18.5 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 CCM00104.1 - 0.0018 17.4 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 CCM00104.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 CCM00104.1 - 0.048 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) FtsJ PF01728.14 CCM00104.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase NDUF_B8 PF05821.6 CCM00105.1 - 2.3e-08 33.9 0.0 3.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) XPG_N PF00752.12 CCM00106.1 - 5.5e-29 100.4 0.0 1.1e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCM00106.1 - 1.5e-25 89.0 0.0 3.4e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region OGFr_N PF04664.8 CCM00106.1 - 0.62 9.3 0.0 1.2 8.4 0.0 1.3 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region ADH_zinc_N PF00107.21 CCM00107.1 - 2.2e-13 49.9 0.0 3.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM00107.1 - 2e-09 38.4 0.0 6.2e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.11 CCM00107.1 - 0.024 13.8 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Citrate_synt PF00285.16 CCM00108.1 - 2.5e-27 95.5 0.0 3.4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Citrate_synt PF00285.16 CCM00109.1 - 1.3e-80 270.8 0.0 1.5e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase DUF2816 PF10992.3 CCM00109.1 - 0.15 11.6 0.2 20 4.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2816) GPI-anchored PF10342.4 CCM00110.1 - 0.0041 17.5 0.2 0.01 16.3 0.2 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA PF00004.24 CCM00111.1 - 2.1e-40 137.9 0.0 4.1e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCM00111.1 - 1.5e-07 31.6 0.5 0.0031 17.6 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 CCM00111.1 - 4.3e-05 22.5 0.0 7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CCM00111.1 - 7.2e-05 22.5 0.4 0.00052 19.7 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCM00111.1 - 7.9e-05 22.6 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCM00111.1 - 0.00038 20.4 0.1 0.0023 17.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CCM00111.1 - 0.00051 19.1 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCM00111.1 - 0.0018 18.2 0.0 0.005 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCM00111.1 - 0.0019 17.8 0.1 0.0046 16.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCM00111.1 - 0.0031 18.3 0.5 0.011 16.5 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CCM00111.1 - 0.0045 17.3 0.1 0.014 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CCM00111.1 - 0.0054 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCM00111.1 - 0.0057 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCM00111.1 - 0.0061 16.2 0.3 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain Bac_DnaA PF00308.13 CCM00111.1 - 0.0081 15.8 0.1 0.021 14.4 0.1 1.6 1 1 0 1 1 1 1 Bacterial dnaA protein KaiC PF06745.8 CCM00111.1 - 0.0089 15.1 0.6 0.21 10.6 0.1 2.3 1 1 1 2 2 2 1 KaiC AAA_28 PF13521.1 CCM00111.1 - 0.0096 15.8 0.5 0.04 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCM00111.1 - 0.014 14.8 0.1 0.052 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CCM00111.1 - 0.028 13.2 0.1 0.073 11.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.21 CCM00111.1 - 0.029 13.8 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CCM00111.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 CCM00111.1 - 0.035 14.1 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 CCM00111.1 - 0.045 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CCM00111.1 - 0.065 13.4 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 CCM00111.1 - 0.065 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 CCM00111.1 - 0.076 11.9 0.1 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.17 CCM00111.1 - 0.081 12.7 0.5 3.5 7.4 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase Mg_chelatase PF01078.16 CCM00111.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCM00111.1 - 0.13 11.8 0.2 0.39 10.2 0.2 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CCM00111.1 - 0.24 11.0 5.0 0.42 10.2 0.1 3.2 4 1 1 5 5 3 0 NACHT domain PhoH PF02562.11 CCM00111.1 - 0.39 9.9 0.1 0.39 9.9 0.0 2.0 3 0 0 3 3 2 0 PhoH-like protein Yip1 PF04893.12 CCM00112.1 - 4.9e-14 52.2 12.5 6.8e-14 51.7 8.7 1.2 1 0 0 1 1 1 1 Yip1 domain DUF4199 PF13858.1 CCM00112.1 - 0.0094 15.8 2.3 0.019 14.8 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) SBP_bac_3 PF00497.15 CCM00113.1 - 0.00012 21.4 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.6 CCM00113.1 - 0.00068 19.2 0.0 0.00095 18.8 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 CCM00113.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.1 CCM00113.1 - 0.0025 17.2 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family Med26 PF08711.6 CCM00115.1 - 1.7e-10 40.2 0.0 3.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Imm2 PF14426.1 CCM00115.1 - 0.19 11.7 2.6 0.73 9.8 0.1 2.8 2 0 0 2 2 2 0 Immunity protein Imm2 Bravo_FIGEY PF13882.1 CCM00115.1 - 0.21 12.5 16.5 1.5 9.7 4.5 2.5 2 0 0 2 2 2 0 Bravo-like intracellular region Fungal_trans PF04082.13 CCM00118.1 - 4.6e-32 110.9 0.0 7.3e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM00118.1 - 4.2e-11 42.5 8.7 7.5e-11 41.7 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 CCM00118.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain ABC_tran PF00005.22 CCM00119.1 - 7.5e-34 116.9 0.0 1.3e-32 113.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 CCM00119.1 - 1.5e-31 109.8 10.2 2.2e-31 109.2 7.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CCM00119.1 - 5.4e-07 29.8 0.2 0.035 14.0 0.0 2.7 2 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 CCM00119.1 - 6.9e-06 25.4 0.2 0.0026 17.0 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCM00119.1 - 0.00048 20.1 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CCM00119.1 - 0.0015 18.6 0.1 0.023 14.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCM00119.1 - 0.0028 17.7 0.0 0.022 14.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCM00119.1 - 0.004 16.6 0.0 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 CCM00119.1 - 0.0044 16.9 1.0 0.053 13.4 0.1 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 CCM00119.1 - 0.0079 16.0 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCM00119.1 - 0.015 16.0 0.1 0.043 14.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCM00119.1 - 0.022 14.4 0.0 0.06 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 CCM00119.1 - 0.034 13.3 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CCM00119.1 - 0.044 13.6 0.1 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CCM00119.1 - 0.046 14.0 0.0 0.51 10.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain CodY PF06018.9 CCM00119.1 - 0.068 12.4 0.4 5.6 6.2 0.0 2.5 3 0 0 3 3 3 0 CodY GAF-like domain MMR_HSR1 PF01926.18 CCM00119.1 - 0.099 12.6 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.10 CCM00119.1 - 0.15 10.7 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ADH_N PF08240.7 CCM00121.1 - 5.6e-21 74.3 0.7 9.3e-21 73.6 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM00121.1 - 8.8e-16 57.6 0.2 2.2e-15 56.3 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCM00121.1 - 0.041 13.0 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 CCM00121.1 - 0.073 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MAF_flag10 PF01973.13 CCM00121.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF115 AlaDh_PNT_C PF01262.16 CCM00121.1 - 0.1 12.1 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.16 CCM00122.1 - 3.4e-66 222.9 0.0 3.8e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CCM00124.1 - 7.7e-68 228.3 0.0 8.9e-68 228.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 CCM00125.1 - 1.8e-28 97.5 33.6 2.8e-09 36.3 3.4 8.9 6 3 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM00125.1 - 2.9e-22 78.1 30.4 5.3e-12 45.3 6.5 7.5 5 3 1 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 CCM00125.1 - 1.9e-20 69.7 28.5 0.021 14.7 0.3 11.4 11 1 1 12 12 12 8 Leucine Rich Repeat LRR_7 PF13504.1 CCM00125.1 - 3.4e-18 62.5 32.1 0.017 15.2 0.4 11.5 12 0 0 12 12 12 7 Leucine rich repeat LRR_6 PF13516.1 CCM00125.1 - 2.5e-17 60.9 21.3 0.093 12.8 0.1 10.6 10 0 0 10 10 10 5 Leucine Rich repeat LRR_5 PF13306.1 CCM00125.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) S10_plectin PF03501.10 CCM00126.1 - 3.8e-42 142.0 0.1 4.5e-42 141.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 CCM00126.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB O-FucT PF10250.4 CCM00127.1 - 0.0022 17.1 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase F-box-like PF12937.2 CCM00128.1 - 0.00021 20.9 0.8 0.00073 19.2 0.3 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CCM00128.1 - 0.2 11.3 1.6 21 4.8 0.0 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) p450 PF00067.17 CCM00130.1 - 8e-09 34.5 0.0 8e-09 34.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL_2 PF13472.1 CCM00131.1 - 4.4e-10 39.9 0.4 1.2e-09 38.5 0.3 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CCM00131.1 - 8.3e-07 29.0 0.3 6.8e-06 26.0 0.2 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 CCM00131.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF4356 PF14266.1 CCM00132.1 - 0.16 10.3 3.7 0.074 11.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4356) DUF3552 PF12072.3 CCM00133.1 - 0.002 17.4 5.0 0.0037 16.4 1.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) DUF3357 PF11837.3 CCM00133.1 - 0.03 14.1 0.4 0.095 12.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF4231 PF14015.1 CCM00133.1 - 0.038 13.9 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) ODV-E18 PF10717.4 CCM00133.1 - 0.048 13.0 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF1980 PF09323.5 CCM00133.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) GAGA_bind PF06217.7 CCM00133.1 - 0.19 11.6 1.6 2.4 8.0 2.1 2.2 2 1 0 2 2 2 0 GAGA binding protein-like family DUF2418 PF10332.4 CCM00134.1 - 6.6e-25 87.2 0.1 1.3e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) zf-H2C2_2 PF13465.1 CCM00135.1 - 1.6e-24 84.8 19.4 1.2e-07 31.6 0.0 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CCM00135.1 - 1.5e-18 65.8 23.3 1.2e-05 25.3 0.8 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM00135.1 - 3.1e-12 45.9 20.0 0.00073 19.7 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCM00135.1 - 3.7e-11 42.8 0.6 0.06 13.5 0.0 4.7 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM00135.1 - 3.3e-07 30.2 5.3 0.077 13.2 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCM00135.1 - 2.2e-06 27.3 3.6 0.21 11.5 0.0 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-TRAF PF02176.13 CCM00135.1 - 0.5 10.7 7.6 0.59 10.5 0.5 2.9 2 1 1 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.7 CCM00135.1 - 2.8 7.6 5.8 20 4.9 0.4 3.0 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger RTA1 PF04479.8 CCM00136.1 - 4.2e-27 95.0 1.6 5.4e-27 94.7 1.1 1.0 1 0 0 1 1 1 1 RTA1 like protein COX7a PF02238.10 CCM00136.1 - 0.34 10.6 0.1 0.34 10.6 0.1 2.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIa DUF1034 PF06280.7 CCM00137.1 - 0.16 12.4 5.3 0.67 10.3 3.0 2.0 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) Polyoma_coat2 PF00761.15 CCM00138.1 - 0.46 9.9 4.1 0.67 9.4 2.8 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein p450 PF00067.17 CCM00139.1 - 3.2e-75 253.4 0.0 3.8e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 CCM00140.1 - 6.8e-25 87.9 0.0 8.7e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM00140.1 - 2.7e-10 40.4 0.0 5.5e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM00140.1 - 6e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM00140.1 - 0.00049 19.6 0.0 0.0017 17.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 CCM00140.1 - 0.0043 16.2 0.2 0.0096 15.0 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CCM00140.1 - 0.18 11.5 1.6 0.37 10.6 1.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CCM00140.1 - 0.22 11.4 1.0 1.1 9.2 0.7 2.1 1 1 0 1 1 1 0 NADH(P)-binding Microtub_assoc PF07989.6 CCM00141.1 - 2.9e-21 75.0 9.8 2.9e-21 75.0 6.8 8.1 7 4 1 8 8 8 3 Microtubule associated Reo_sigmaC PF04582.7 CCM00141.1 - 0.00015 21.0 32.8 0.026 13.7 0.8 6.3 3 1 2 6 6 6 3 Reovirus sigma C capsid protein Mto2_bdg PF12808.2 CCM00141.1 - 0.0014 18.6 10.9 0.0014 18.6 7.6 10.9 10 3 0 10 10 10 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Sec2p PF06428.6 CCM00141.1 - 0.016 15.0 1.7 0.016 15.0 1.2 12.3 4 4 9 14 14 14 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.5 CCM00141.1 - 0.052 13.6 0.3 0.052 13.6 0.2 8.6 2 2 6 9 9 9 0 Fibrinogen alpha/beta chain family DUF4250 PF14056.1 CCM00141.1 - 0.26 11.0 11.1 0.84 9.4 1.3 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) DUF92 PF01940.11 CCM00142.1 - 4.9e-60 202.4 6.9 6.7e-60 202.0 4.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF3169 PF11368.3 CCM00142.1 - 0.073 12.2 0.5 0.19 10.8 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) C2 PF00168.25 CCM00144.1 - 4.5e-10 39.2 0.0 7.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain F-box PF00646.28 CCM00146.1 - 4.2e-05 23.0 0.2 0.00011 21.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCM00146.1 - 0.00025 20.7 0.5 0.0006 19.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CCM00146.1 - 0.0023 17.5 0.0 0.31 10.7 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 CCM00146.1 - 0.19 12.2 2.9 2.6 8.7 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat PNK3P PF08645.6 CCM00147.1 - 5.8e-44 149.3 0.0 9.5e-44 148.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 CCM00147.1 - 3.9e-23 81.9 0.1 2.5e-22 79.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCM00147.1 - 2.2e-06 26.9 0.0 0.029 13.4 0.0 2.5 1 1 1 2 2 2 2 Zeta toxin KTI12 PF08433.5 CCM00147.1 - 0.0084 15.3 1.4 0.79 8.8 1.0 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 CCM00147.1 - 0.029 14.3 0.0 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.1 CCM00147.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.7 CCM00148.1 - 3e-46 154.8 27.7 1.8e-08 34.7 0.0 7.8 7 0 0 7 7 7 7 Sel1 repeat PITH PF06201.8 CCM00148.1 - 9.5e-43 145.5 1.1 1.8e-42 144.7 0.8 1.4 1 0 0 1 1 1 1 PITH domain VP4_haemagglut PF00426.13 CCM00148.1 - 0.063 11.2 0.4 0.088 10.7 0.3 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) DUF1838 PF08894.6 CCM00149.1 - 0.12 11.6 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Mito_fiss_reg PF05308.6 CCM00149.1 - 0.89 8.8 5.2 0.98 8.7 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator JmjC PF02373.17 CCM00150.1 - 8.6e-08 32.4 1.5 1e-06 28.9 1.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 CCM00150.1 - 0.00025 20.6 1.8 0.00051 19.6 1.3 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.1 CCM00150.1 - 0.0015 18.1 1.3 0.0068 15.9 0.9 1.9 1 1 0 1 1 1 1 Cupin-like domain Prok-RING_1 PF14446.1 CCM00150.1 - 0.014 15.0 3.0 0.031 13.9 2.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 SRP72 PF08492.7 CCM00150.1 - 0.21 11.9 0.0 0.21 11.9 0.0 2.7 3 0 0 3 3 3 0 SRP72 RNA-binding domain PGK PF00162.14 CCM00151.1 - 6.2e-146 485.8 0.1 7.1e-146 485.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Peripla_BP_4 PF13407.1 CCM00151.1 - 0.0072 15.7 1.0 0.012 15.0 0.3 1.6 2 0 0 2 2 2 1 Periplasmic binding protein domain DUF4061 PF13270.1 CCM00152.1 - 0.23 11.5 7.9 0.69 10.0 5.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) YjgP_YjgQ PF03739.9 CCM00152.1 - 1.1 7.8 3.0 1.4 7.6 2.1 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Atg14 PF10186.4 CCM00152.1 - 1.8 7.4 9.9 2.4 7.0 6.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PH PF00169.24 CCM00153.1 - 1.2e-09 38.3 0.0 2.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 PH domain LCAT PF02450.10 CCM00154.1 - 6.2e-57 193.3 0.4 3e-56 191.0 0.3 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CCM00154.1 - 0.0058 16.5 0.1 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM00154.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CCM00154.1 - 0.011 15.0 0.1 0.026 13.8 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 CCM00154.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Trp_halogenase PF04820.9 CCM00155.1 - 2.8e-27 95.4 0.6 1e-11 44.1 0.1 3.7 2 2 1 3 3 3 2 Tryptophan halogenase FAD_binding_3 PF01494.14 CCM00155.1 - 3.9e-08 32.7 0.0 2.6e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CCM00155.1 - 4.9e-06 25.6 0.2 0.0037 16.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCM00155.1 - 8.4e-06 25.7 0.1 4.3e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CCM00155.1 - 0.0012 17.9 0.5 0.0028 16.7 0.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCM00155.1 - 0.0014 18.5 0.6 0.0023 17.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM00155.1 - 0.0023 16.4 0.1 0.0051 15.3 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 CCM00155.1 - 0.0027 16.6 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCM00155.1 - 0.0041 16.0 0.1 0.014 14.2 0.1 1.9 1 0 0 1 1 1 1 FAD binding domain DUF525 PF04379.9 CCM00155.1 - 0.17 11.8 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF525) TPR_7 PF13176.1 CCM00156.1 - 0.081 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2408 PF10303.4 CCM00157.1 - 0.025 14.6 0.6 3.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF349 PF03993.7 CCM00157.1 - 1.3 9.2 4.5 0.22 11.6 0.4 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) NAD_kinase PF01513.16 CCM00160.1 - 3.2e-60 203.3 0.0 4.4e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 CCM00160.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Cytochrom_B_N PF00033.14 CCM00161.1 - 0.045 13.1 1.6 0.083 12.2 1.1 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 CCM00161.1 - 0.22 10.8 2.0 0.41 9.9 1.4 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF3649 PF12365.3 CCM00161.1 - 2 7.9 5.8 4.6 6.8 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) MFS_1 PF07690.11 CCM00162.1 - 2.3e-39 135.0 12.2 5.4e-22 77.9 6.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM00162.1 - 3.4e-11 42.4 4.7 1.7e-10 40.0 0.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 CCM00162.1 - 0.00059 18.3 9.1 0.0039 15.6 6.3 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein DUF4131 PF13567.1 CCM00162.1 - 0.02 14.3 7.6 0.94 8.8 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) XPG_I_2 PF12813.2 CCM00163.1 - 7.7e-09 35.3 0.1 2.4e-07 30.5 0.0 2.9 3 0 0 3 3 3 1 XPG domain containing Methyltransf_23 PF13489.1 CCM00165.1 - 3.9e-08 33.1 0.0 5.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM00165.1 - 1.4e-07 31.9 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM00165.1 - 9.2e-07 28.5 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM00165.1 - 4.9e-06 26.9 0.0 9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00165.1 - 9.1e-06 26.2 0.0 1.6e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCM00165.1 - 2e-05 24.0 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CCM00165.1 - 0.00046 20.2 0.0 0.00098 19.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM00165.1 - 0.0072 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM00165.1 - 0.016 14.3 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CCM00165.1 - 0.044 13.3 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.12 CCM00165.1 - 0.046 12.7 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase AMP-binding PF00501.23 CCM00166.1 - 2.5e-60 204.0 0.0 3.3e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1456 PF07308.8 CCM00166.1 - 0.2 11.7 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) ketoacyl-synt PF00109.21 CCM00168.1 - 4.3e-51 173.8 0.0 8.7e-51 172.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CCM00168.1 - 2.2e-32 112.1 0.1 1.3e-27 96.5 0.0 2.6 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 CCM00168.1 - 6.4e-30 104.2 0.5 1.1e-24 87.2 0.0 3.7 4 0 0 4 4 4 2 short chain dehydrogenase Acyl_transf_1 PF00698.16 CCM00168.1 - 2.1e-28 99.5 0.3 1.1e-27 97.2 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 CCM00168.1 - 5.7e-27 94.2 0.0 1.1e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 CCM00168.1 - 4.8e-26 90.9 0.0 2.4e-25 88.6 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 CCM00168.1 - 6.6e-20 71.4 0.3 1.9e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Epimerase PF01370.16 CCM00168.1 - 1.1e-08 34.7 0.0 3.6e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CCM00168.1 - 4.5e-06 26.8 0.4 9.7e-06 25.7 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 CCM00168.1 - 0.0026 16.7 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 CCM00168.1 - 0.016 14.8 0.0 0.047 13.3 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.10 CCM00168.1 - 0.025 13.5 0.1 0.075 11.9 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PCRF PF03462.13 CCM00168.1 - 0.41 10.3 0.0 1 9.0 0.0 1.6 1 0 0 1 1 1 0 PCRF domain Pyr_redox_3 PF13738.1 CCM00170.1 - 1.9e-17 64.0 0.1 1.2e-15 58.1 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM00170.1 - 1.1e-07 31.7 0.7 7.8e-06 25.8 0.0 3.2 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CCM00170.1 - 2.4e-06 26.6 0.2 0.0044 15.9 0.7 3.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM00170.1 - 7.3e-06 25.9 0.0 0.00016 21.6 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM00170.1 - 1.4e-05 24.2 0.1 0.0029 16.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM00170.1 - 2e-05 24.4 0.0 0.00014 21.6 0.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 CCM00170.1 - 5.3e-05 23.5 0.0 0.025 15.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM00170.1 - 0.00026 20.1 0.0 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FMO-like PF00743.14 CCM00170.1 - 0.00035 18.9 0.0 0.021 13.0 0.0 2.6 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 CCM00170.1 - 0.0036 16.4 0.0 0.018 14.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 CCM00170.1 - 0.0043 17.1 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CCM00170.1 - 0.0063 16.7 0.0 3.5 7.9 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 CCM00170.1 - 0.011 14.6 0.0 0.99 8.2 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 CCM00170.1 - 0.019 14.3 0.5 0.99 8.8 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 CCM00170.1 - 0.025 14.4 0.2 0.068 12.9 0.0 1.7 2 0 0 2 2 2 0 ThiF family Strep_67kDa_ant PF06100.6 CCM00170.1 - 0.03 12.6 0.1 1.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Amino_oxidase PF01593.19 CCM00170.1 - 0.042 12.9 0.0 1.4 7.9 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.17 CCM00170.1 - 0.1 11.3 0.4 1.3 7.7 0.0 2.1 2 1 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 CCM00170.1 - 0.12 10.8 0.0 0.2 10.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 CCM00170.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FH2 PF02181.18 CCM00171.1 - 6.4e-72 242.4 0.2 7.6e-72 242.2 0.1 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain IU_nuc_hydro PF01156.14 CCM00172.1 - 2.1e-92 309.7 0.0 2.4e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RRN3 PF05327.6 CCM00173.1 - 1.7e-158 528.2 0.0 1.7e-158 528.2 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 GOLD_2 PF13897.1 CCM00173.1 - 0.29 11.3 1.8 0.65 10.2 1.2 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking LNS2 PF08235.8 CCM00174.1 - 8.4e-72 239.8 0.1 1.4e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CCM00174.1 - 2e-30 104.6 0.0 2.3e-29 101.2 0.0 2.4 1 1 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 CCM00174.1 - 0.14 11.4 0.1 0.48 9.7 0.0 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Complex1_LYR PF05347.10 CCM00175.1 - 2.1e-08 33.8 1.0 3.3e-08 33.1 0.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCM00175.1 - 9.8e-07 28.8 0.7 1.4e-06 28.3 0.5 1.3 1 0 0 1 1 1 1 Complex1_LYR-like tRNA-synt_1 PF00133.17 CCM00175.1 - 0.032 12.2 0.0 0.036 12.0 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) MFS_1 PF07690.11 CCM00176.1 - 2.6e-22 79.0 56.5 1.8e-18 66.3 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 CCM00177.1 - 2.2e-15 55.8 12.5 0.004 16.9 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CCM00177.1 - 0.00023 20.9 0.0 0.092 12.4 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CCM00177.1 - 0.00061 19.3 0.1 0.16 11.6 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 CCM00177.1 - 0.0099 14.2 0.0 0.16 10.2 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain IKI3 PF04762.7 CCM00177.1 - 0.077 10.7 0.0 1.5 6.5 0.0 2.3 2 1 1 3 3 3 0 IKI3 family Sigma54_AID PF00309.15 CCM00177.1 - 0.096 12.1 0.7 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Coatomer_WDAD PF04053.9 CCM00177.1 - 0.1 11.3 0.0 5.5 5.6 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region adh_short PF00106.20 CCM00179.1 - 3.8e-13 49.6 0.3 6.5e-13 48.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Btz PF09405.5 CCM00179.1 - 1.8e-09 37.7 1.9 1.8e-09 37.7 1.3 2.3 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding KR PF08659.5 CCM00179.1 - 2.3e-05 24.1 0.1 3.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCM00179.1 - 0.032 14.2 0.1 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Uso1_p115_head PF04869.9 CCM00179.1 - 0.22 10.2 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region DLIC PF05783.6 CCM00180.1 - 2.3e-33 115.5 2.6 2e-24 86.1 0.0 4.1 2 2 1 3 3 3 2 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.22 CCM00180.1 - 0.00069 19.0 0.0 0.046 13.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCM00180.1 - 0.0011 19.4 0.0 0.0051 17.2 0.0 2.1 2 1 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 CCM00180.1 - 0.0024 17.8 0.0 0.0078 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 CCM00180.1 - 0.0031 17.4 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase KTI12 PF08433.5 CCM00180.1 - 0.0068 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 T2SE PF00437.15 CCM00180.1 - 0.0098 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Dynamin_N PF00350.18 CCM00180.1 - 0.015 15.0 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.1 CCM00180.1 - 0.024 14.1 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 CCM00180.1 - 0.049 13.1 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 CCM00180.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 CCM00180.1 - 0.073 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCM00180.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CCM00180.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP41 PF04176.8 CCM00181.1 - 4e-54 182.6 0.0 4.9e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family CMAS PF02353.15 CCM00182.1 - 1.6e-53 181.5 0.0 2.1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CCM00182.1 - 4.3e-07 29.7 0.0 1.2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM00182.1 - 1.7e-06 28.0 0.1 3.4e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00182.1 - 7.1e-06 26.5 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM00182.1 - 1.7e-05 25.1 0.0 4.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM00182.1 - 0.00032 20.3 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CCM00182.1 - 0.003 17.1 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.8 CCM00182.1 - 0.0031 16.8 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 CCM00182.1 - 0.0033 17.8 0.0 0.0071 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCM00182.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 CCM00182.1 - 0.01 16.6 0.0 0.043 14.6 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain PrmA PF06325.8 CCM00182.1 - 0.036 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 CCM00182.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Abhydrolase_4 PF08386.5 CCM00183.1 - 2.2e-17 62.8 0.0 3.9e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 CCM00183.1 - 2.6e-14 53.3 0.0 3.6e-13 49.6 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCM00183.1 - 4.4e-10 39.8 0.1 2.2e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM00183.1 - 9.1e-06 25.4 0.0 0.00054 19.7 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-RanBP PF00641.13 CCM00184.1 - 0.091 11.8 0.6 0.13 11.3 0.4 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others FA_hydroxylase PF04116.8 CCM00186.1 - 6.3e-13 49.1 20.7 6.3e-13 49.1 14.4 2.2 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Lipase_chap PF03280.9 CCM00186.1 - 0.069 12.6 0.1 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein DUF4243 PF14027.1 CCM00189.1 - 6.4e-95 318.3 0.0 7.6e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF4243 PF14027.1 CCM00192.1 - 1.7e-94 316.9 0.0 2e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) F-box-like PF12937.2 CCM00193.1 - 6.1e-07 29.0 1.8 1.3e-06 28.0 0.3 2.4 2 0 0 2 2 2 1 F-box-like Cys_Met_Meta_PP PF01053.15 CCM00194.1 - 5.7e-145 482.4 0.0 6.4e-145 482.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCM00194.1 - 1e-15 57.6 0.2 1.9e-13 50.2 0.1 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CCM00194.1 - 1.3e-10 40.7 0.1 2.6e-10 39.8 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCM00194.1 - 1.1e-07 30.9 0.8 3.2e-07 29.4 0.1 1.9 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCM00194.1 - 2.3e-06 26.9 0.0 5.1e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 CCM00194.1 - 7e-05 21.6 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 CCM00194.1 - 0.015 13.5 0.0 0.021 13.1 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 CCM00194.1 - 0.037 12.5 0.0 0.054 11.9 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) LRR_8 PF13855.1 CCM00195.1 - 8.1e-05 22.2 0.0 0.096 12.4 0.0 3.9 3 0 0 3 3 3 1 Leucine rich repeat F-box-like PF12937.2 CCM00195.1 - 0.00015 21.3 1.9 0.00062 19.4 1.2 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CCM00195.1 - 0.0058 16.2 0.1 7.1 6.3 0.0 4.8 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) Peptidase_S9 PF00326.16 CCM00196.1 - 5.8e-42 143.3 0.0 1.4e-41 142.0 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCM00196.1 - 6e-12 45.5 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM00196.1 - 1e-07 32.0 0.0 6.2e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CCM00196.1 - 1.4e-06 27.7 0.0 2.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 CCM00196.1 - 4.9e-06 26.2 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 CCM00196.1 - 3.9e-05 23.4 0.0 0.0005 19.9 0.0 2.6 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_2 PF02230.11 CCM00196.1 - 0.00066 19.1 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 CCM00196.1 - 0.0014 18.1 0.0 0.15 11.6 0.0 2.3 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 CCM00196.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.15 CCM00196.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative esterase LIP PF03583.9 CCM00196.1 - 0.047 12.9 0.0 0.095 11.8 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase PD40 PF07676.7 CCM00196.1 - 0.061 12.9 1.7 0.24 11.0 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat BAAT_C PF08840.6 CCM00196.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PhyH PF05721.8 CCM00198.1 - 2.9e-10 40.5 0.1 4.3e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SAP PF02037.22 CCM00199.1 - 0.008 15.6 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 SAP domain Acyltransferase PF01553.16 CCM00200.1 - 4.9e-19 68.0 0.0 7e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Ribosomal_L21e PF01157.13 CCM00200.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L21e Peptidase_M36 PF02128.10 CCM00201.1 - 3e-127 424.5 5.5 1.5e-126 422.2 3.8 2.1 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 CCM00201.1 - 1e-09 37.6 2.8 1.9e-09 36.8 2.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif ABC_tran PF00005.22 CCM00202.1 - 7.6e-51 172.0 0.0 3.4e-28 98.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCM00202.1 - 1.4e-50 172.2 32.8 1.1e-25 90.6 9.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CCM00202.1 - 2.9e-10 39.7 2.4 0.009 15.2 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCM00202.1 - 4.4e-08 32.5 0.3 0.013 14.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CCM00202.1 - 5.6e-08 32.9 0.7 0.011 15.7 0.0 3.7 3 1 0 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.18 CCM00202.1 - 1e-07 31.8 0.1 0.012 15.5 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 CCM00202.1 - 1.8e-07 31.6 0.5 0.036 14.5 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein Dynamin_N PF00350.18 CCM00202.1 - 1.7e-06 27.9 0.1 0.0043 16.8 0.0 2.5 2 0 0 2 2 2 2 Dynamin family Zeta_toxin PF06414.7 CCM00202.1 - 7.5e-06 25.1 0.3 0.13 11.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 CCM00202.1 - 2.5e-05 23.5 0.3 0.039 13.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 CCM00202.1 - 6e-05 23.1 0.3 0.031 14.2 0.1 3.2 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 CCM00202.1 - 9.3e-05 21.4 0.3 0.064 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 CCM00202.1 - 0.00011 21.7 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 CCM00202.1 - 0.00015 22.2 1.8 0.16 12.2 0.2 2.8 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 CCM00202.1 - 0.00021 22.0 0.0 0.51 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCM00202.1 - 0.00038 19.9 0.0 0.71 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 CCM00202.1 - 0.00046 19.0 0.4 0.62 8.7 0.0 2.3 2 0 0 2 2 2 2 ArgK protein ATP-synt_ab PF00006.20 CCM00202.1 - 0.00062 19.3 0.3 0.22 10.9 0.1 3.3 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 CCM00202.1 - 0.00065 19.4 0.9 0.7 9.5 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CCM00202.1 - 0.0011 18.4 0.7 0.24 10.8 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCM00202.1 - 0.0012 19.1 0.2 1.5 9.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CCM00202.1 - 0.0016 17.0 2.2 0.071 11.7 0.1 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 CCM00202.1 - 0.0017 17.2 0.0 1.3 7.8 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.12 CCM00202.1 - 0.0022 17.8 2.6 0.73 9.6 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 CCM00202.1 - 0.003 17.7 0.5 7 6.8 0.1 3.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CCM00202.1 - 0.0055 16.3 0.4 3.3 7.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CCM00202.1 - 0.0055 16.3 0.1 1.4 8.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 CCM00202.1 - 0.0063 15.9 3.5 0.74 9.2 0.3 3.0 3 0 0 3 3 3 1 AAA-like domain AAA_15 PF13175.1 CCM00202.1 - 0.0096 15.0 0.0 1.6 7.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 CCM00202.1 - 0.011 15.6 0.3 1.4 8.8 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 CCM00202.1 - 0.016 14.8 0.8 1.2 8.8 0.0 3.3 3 1 0 4 4 3 0 Archaeal ATPase KAP_NTPase PF07693.9 CCM00202.1 - 0.016 14.1 0.0 3.9 6.3 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain ATP_bind_1 PF03029.12 CCM00202.1 - 0.037 13.5 0.0 9.5 5.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 CCM00202.1 - 0.038 13.6 0.4 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CCM00202.1 - 0.057 13.5 0.0 22 5.2 0.0 3.4 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.1 CCM00202.1 - 0.069 13.0 0.0 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CCM00202.1 - 0.074 12.5 0.1 7.8 5.9 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CCM00202.1 - 0.092 12.9 0.0 29 4.8 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3728 PF12528.3 CCM00202.1 - 0.12 12.8 0.1 0.42 11.0 0.0 1.9 2 0 0 2 2 1 0 Prepilin peptidase dependent protein C (DUF3728) Glyco_hydro_88 PF07470.8 CCM00203.1 - 4.6e-18 65.3 0.8 6.9e-18 64.7 0.6 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Abhydrolase_3 PF07859.8 CCM00204.1 - 5.4e-12 45.7 0.6 7.7e-12 45.2 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM00204.1 - 8.5e-05 22.3 0.1 0.0001 22.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CCM00204.1 - 9.6e-05 21.2 2.7 0.0013 17.5 1.9 2.0 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 CCM00204.1 - 0.00013 20.7 0.0 0.00016 20.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 CCM00204.1 - 0.0015 18.4 2.8 0.0018 18.1 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CCM00204.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) CRAL_TRIO PF00650.15 CCM00205.1 - 9e-30 103.2 0.1 1.1e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCM00205.1 - 3.6e-09 36.6 0.1 9.6e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCM00205.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.6 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain DUF262 PF03235.9 CCM00207.1 - 6.1e-15 55.7 0.4 3.2e-14 53.4 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF262 MAD PF05557.8 CCM00208.1 - 4.2e-41 140.8 55.3 1.2e-40 139.3 37.5 1.8 1 1 0 1 1 1 1 Mitotic checkpoint protein TMF_TATA_bd PF12325.3 CCM00208.1 - 0.0014 18.3 9.6 0.0014 18.3 6.7 6.7 5 4 1 6 6 6 2 TATA element modulatory factor 1 TATA binding FlxA PF14282.1 CCM00208.1 - 0.0091 15.9 7.5 0.0091 15.9 5.2 6.3 5 3 2 7 7 7 2 FlxA-like protein DUF4164 PF13747.1 CCM00208.1 - 0.014 15.5 2.9 0.014 15.5 2.0 7.3 4 2 1 6 6 6 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 CCM00208.1 - 0.97 9.7 18.4 43 4.4 0.0 6.6 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.7 CCM00208.1 - 2.3 8.2 0.0 2.3 8.2 0.0 8.2 9 0 0 9 9 9 0 Viral A-type inclusion protein repeat SEP PF08059.8 CCM00209.1 - 5e-23 81.2 0.0 1.3e-22 79.8 0.0 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 CCM00209.1 - 2.1e-15 56.5 0.0 3.3e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 UBX domain MAGE PF01454.14 CCM00210.1 - 1.4e-36 125.7 0.0 6.6e-34 116.9 0.0 2.2 2 0 0 2 2 2 2 MAGE family DUF1188 PF06690.6 CCM00210.1 - 0.037 13.1 0.0 0.72 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) PBP1_TM PF14812.1 CCM00210.1 - 4.9 7.5 10.8 3.8 7.8 4.0 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tubulin PF00091.20 CCM00211.1 - 6.8e-69 231.9 0.0 1.3e-68 231.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCM00211.1 - 2.1e-49 166.7 0.1 3.3e-49 166.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCM00211.1 - 8.4e-07 29.0 0.0 2.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CCM00211.1 - 0.021 14.2 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain EamA PF00892.15 CCM00212.1 - 1.5e-25 89.6 22.3 2.1e-14 53.6 2.6 2.6 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CCM00212.1 - 3.7e-08 33.5 20.7 1.8e-07 31.3 0.7 3.1 3 1 0 3 3 3 2 Multidrug resistance efflux transporter E1-N PF14463.1 CCM00212.1 - 0.047 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 E1 N-terminal domain DUF3671 PF12420.3 CCM00212.1 - 0.47 10.4 5.1 1.1 9.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function zf-C2H2_4 PF13894.1 CCM00213.1 - 0.011 15.9 14.0 0.028 14.7 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-HYPF PF07503.7 CCM00213.1 - 0.027 13.8 4.5 0.31 10.4 0.6 2.6 2 0 0 2 2 2 0 HypF finger zf-C2H2_jaz PF12171.3 CCM00213.1 - 0.16 12.1 1.3 10 6.3 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CCM00213.1 - 0.81 10.1 16.9 0.2 12.0 1.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type TAFII28 PF04719.9 CCM00214.1 - 5.3e-29 99.8 0.1 7.2e-29 99.4 0.1 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 CCM00214.1 - 0.00024 21.0 0.1 0.00036 20.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C2H2 PF00096.21 CCM00215.1 - 1.8e-08 34.2 3.3 0.00036 20.6 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM00215.1 - 9e-05 22.5 4.7 0.11 12.8 0.1 3.7 2 1 1 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCM00215.1 - 0.00011 22.0 0.6 0.092 12.6 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCM00215.1 - 0.048 13.8 0.4 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM00215.1 - 0.19 12.0 1.2 2.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCM00215.1 - 0.33 11.0 3.1 15 5.7 0.0 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Methyltransf_23 PF13489.1 CCM00217.1 - 7.8e-12 45.2 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM00217.1 - 6.1e-07 29.8 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00217.1 - 1.8e-06 28.5 0.0 3.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM00217.1 - 2.4e-05 23.9 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM00217.1 - 0.00023 21.5 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM00217.1 - 0.015 15.3 0.0 0.031 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CCM00218.1 - 3e-11 43.3 0.0 3.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM00218.1 - 2.9e-07 30.8 0.0 5.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00218.1 - 9.6e-07 29.3 0.0 2.5e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM00218.1 - 7.5e-05 22.3 0.0 9.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM00218.1 - 0.00031 21.1 0.0 0.0005 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCM00218.1 - 0.0098 14.6 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 CCM00218.1 - 0.053 13.8 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CCM00218.1 - 0.063 13.3 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CCM00218.1 - 0.093 11.7 0.1 0.19 10.7 0.0 1.4 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Ras PF00071.17 CCM00219.1 - 1.3e-56 190.4 0.0 1.5e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM00219.1 - 7e-18 65.2 0.0 1.1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM00219.1 - 2.4e-15 56.2 0.0 3.2e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCM00219.1 - 1.1e-07 31.2 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCM00219.1 - 5.8e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCM00219.1 - 7.7e-05 22.1 0.0 0.00017 21.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCM00219.1 - 0.022 13.9 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF4211 PF13926.1 CCM00219.1 - 0.025 14.0 0.2 0.1 12.0 0.0 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4211) Septin PF00735.13 CCM00219.1 - 0.026 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 CCM00219.1 - 0.057 12.0 1.5 0.66 8.6 0.2 2.1 1 1 0 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 CCM00219.1 - 0.081 12.1 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCM00219.1 - 0.11 11.9 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CCM00219.1 - 0.12 12.3 0.1 0.67 9.9 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain PAP2_3 PF14378.1 CCM00220.1 - 3.6e-10 39.6 8.8 3.6e-10 39.6 6.1 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.16 CCM00220.1 - 1.4e-06 28.0 22.1 1.4e-05 24.7 15.2 2.6 1 1 0 1 1 1 1 PAP2 superfamily Dynamin_M PF01031.15 CCM00221.1 - 3.3e-27 95.0 0.0 7.5e-13 47.9 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 CCM00221.1 - 8.8e-12 45.1 0.1 3.5e-11 43.1 0.1 1.9 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 CCM00221.1 - 5.8e-05 22.9 1.3 5.8e-05 22.9 0.9 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain DUF1476 PF07345.6 CCM00221.1 - 0.02 15.1 0.0 1.8 8.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1476) Zeta_toxin PF06414.7 CCM00221.1 - 0.068 12.2 0.1 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 CCM00221.1 - 0.13 12.2 0.1 0.42 10.5 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase MerR-DNA-bind PF09278.6 CCM00221.1 - 2.2 8.7 6.5 4.1 7.8 0.1 3.7 4 0 0 4 4 4 0 MerR, DNA binding Pectinesterase PF01095.14 CCM00222.1 - 4.9e-23 81.1 0.0 1.1e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Pectinesterase DUF3905 PF13045.1 CCM00222.1 - 0.065 13.0 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3905) SMC_N PF02463.14 CCM00223.1 - 1.4e-62 210.8 15.3 2.7e-61 206.6 10.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCM00223.1 - 5.2e-24 84.5 0.6 2.3e-22 79.2 0.1 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCM00223.1 - 7.3e-13 49.1 8.2 4.2e-06 26.9 0.1 3.3 3 1 0 3 3 3 2 AAA domain Reo_sigmaC PF04582.7 CCM00223.1 - 1.2e-06 27.9 23.9 0.00077 18.7 3.8 5.2 4 2 2 6 6 6 4 Reovirus sigma C capsid protein AAA_23 PF13476.1 CCM00223.1 - 2.1e-06 28.2 43.9 2.1e-06 28.2 30.4 7.2 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCM00223.1 - 3.3e-05 23.3 0.0 8.9e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.6 CCM00223.1 - 0.00029 19.6 21.4 0.00029 19.6 14.9 6.9 2 2 6 8 8 8 2 Spc7 kinetochore protein ATG16 PF08614.6 CCM00223.1 - 0.0014 18.4 13.5 0.0014 18.4 9.3 6.3 4 2 1 5 5 5 2 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 CCM00223.1 - 0.0017 16.9 34.9 0.0017 16.9 24.2 5.8 3 2 4 7 7 7 2 AAA domain Filament PF00038.16 CCM00223.1 - 0.42 10.0 92.4 0.75 9.2 26.1 6.3 3 2 3 6 6 6 0 Intermediate filament protein DUF262 PF03235.9 CCM00224.1 - 0.016 15.1 0.3 0.016 15.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF262 OPT PF03169.10 CCM00225.1 - 2.7e-196 653.7 57.7 3.1e-196 653.5 40.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4229 PF14012.1 CCM00225.1 - 0.34 10.8 7.9 0.87 9.5 2.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Pro_isomerase PF00160.16 CCM00226.1 - 5e-48 163.2 0.5 5.7e-48 163.0 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1708 PF08101.6 CCM00227.1 - 8.3e-12 44.6 0.0 1e-09 37.7 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1708) DNA_primase_S PF01896.14 CCM00228.1 - 4.9e-51 172.3 0.1 7.2e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit WXG100 PF06013.7 CCM00228.1 - 0.092 12.7 0.9 0.2 11.6 0.3 1.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG ABC_tran PF00005.22 CCM00229.1 - 4.4e-49 166.3 0.0 1.4e-28 99.9 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 CCM00229.1 - 6.8e-36 124.0 22.3 2.2e-20 73.2 3.6 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 CCM00229.1 - 1.8e-08 33.8 1.6 0.0023 17.2 0.4 3.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCM00229.1 - 5.7e-06 26.5 0.4 0.18 11.7 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 CCM00229.1 - 2.7e-05 23.6 0.0 0.094 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CCM00229.1 - 0.0018 17.7 0.0 0.46 9.8 0.0 2.7 2 1 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 CCM00229.1 - 0.002 17.6 0.5 0.15 11.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCM00229.1 - 0.0089 16.1 0.5 6 7.0 0.1 3.3 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 CCM00229.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_16 PF13191.1 CCM00229.1 - 0.021 14.8 0.0 2.3 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 CCM00229.1 - 0.055 12.3 0.0 0.3 9.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 CCM00229.1 - 0.058 13.8 0.0 17 5.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 CCM00229.1 - 0.072 12.5 0.1 2.6 7.4 0.0 2.6 2 1 1 3 3 3 0 FtsK/SpoIIIE family KaiC PF06745.8 CCM00229.1 - 0.16 11.0 0.0 18 4.3 0.0 2.4 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.18 CCM00229.1 - 0.22 11.4 0.0 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 CCM00229.1 - 0.24 11.6 0.4 30 4.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CCM00229.1 - 0.26 10.4 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 TMEM169 PF15052.1 CCM00230.1 - 0.14 12.0 2.4 0.17 11.7 1.6 1.1 1 0 0 1 1 1 0 TMEM169 protein family CAML PF14963.1 CCM00230.1 - 0.71 9.1 3.8 0.85 8.9 2.7 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand EMP24_GP25L PF01105.19 CCM00231.1 - 4.9e-39 133.9 0.0 5.6e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dus PF01207.12 CCM00232.1 - 1.7e-51 174.9 0.0 2e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 CCM00232.1 - 0.008 15.4 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 CCM00232.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IGPS PF00218.16 CCM00232.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase IMPDH PF00478.20 CCM00232.1 - 0.079 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain adh_short PF00106.20 CCM00233.1 - 6.6e-33 113.9 1.1 8.6e-33 113.6 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM00233.1 - 1.3e-24 87.3 0.0 1.7e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM00233.1 - 1.6e-16 60.4 0.3 2.3e-16 59.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCM00233.1 - 0.0003 20.5 0.4 0.00071 19.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CCM00233.1 - 0.00037 19.9 0.2 0.00063 19.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM00233.1 - 0.0085 16.1 0.9 0.037 14.0 0.6 2.0 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CCM00233.1 - 0.032 13.1 0.4 0.12 11.2 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 CCM00234.1 - 1.5e-18 66.6 0.0 4.4e-11 42.4 0.0 2.4 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM00234.1 - 6.8e-05 23.7 0.1 0.00088 20.1 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CCM00234.1 - 0.0003 20.3 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 CCM00234.1 - 0.00084 19.9 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM00234.1 - 0.019 15.4 0.1 0.046 14.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 CCM00234.1 - 0.048 13.6 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 CCM00234.1 - 0.051 12.7 0.0 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_2 PF00891.13 CCM00235.1 - 2.2e-28 99.1 0.0 4.6e-28 98.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 CCM00235.1 - 0.00016 21.4 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 CCM00235.1 - 0.0095 15.2 0.0 0.04 13.2 0.0 1.9 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 CCM00235.1 - 0.019 15.5 0.0 0.044 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TusA PF01206.12 CCM00235.1 - 0.12 12.0 0.0 0.41 10.2 0.0 1.9 1 0 0 1 1 1 0 Sulfurtransferase TusA MR_MLE_C PF13378.1 CCM00236.1 - 1.6e-27 95.6 0.0 3.9e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 CCM00236.1 - 4.4e-21 75.0 0.0 9.2e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 CCM00236.1 - 8.7e-09 35.7 0.0 8.6e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Peptidase_S41 PF03572.13 CCM00236.1 - 7.7e-05 22.1 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 PWI PF01480.12 CCM00237.1 - 1.1e-26 92.7 0.0 1.7e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 PWI domain SET PF00856.23 CCM00238.1 - 6.3e-11 42.8 0.0 2.1e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 SET domain SPC25 PF06703.6 CCM00240.1 - 2.3e-31 108.5 0.0 3e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4173 PF13777.1 CCM00240.1 - 0.078 12.2 0.5 0.12 11.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) ERG2_Sigma1R PF04622.7 CCM00241.1 - 2.5e-81 272.0 0.1 2.8e-81 271.9 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein GST_C_3 PF14497.1 CCM00242.1 - 8e-09 35.8 0.0 1.2e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCM00242.1 - 5.5e-06 26.2 0.0 1.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCM00242.1 - 0.00011 22.3 0.1 0.0015 18.6 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM00242.1 - 0.0078 16.0 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NADH_u_ox_C PF12853.2 CCM00242.1 - 0.017 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Amino_oxidase PF01593.19 CCM00243.1 - 1.4e-10 40.8 0.0 1.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCM00243.1 - 1.8e-09 37.5 0.0 4.9e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCM00243.1 - 0.00011 21.2 0.0 0.00032 19.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM00243.1 - 0.017 14.8 0.0 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CCM00243.1 - 0.024 14.6 0.0 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM00243.1 - 0.035 14.5 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCM00243.1 - 0.086 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DSPc PF00782.15 CCM00244.1 - 2.5e-30 104.7 0.0 3.1e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCM00244.1 - 0.0027 17.0 0.0 0.0034 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CCM00244.1 - 0.068 13.4 0.1 1.1 9.4 0.0 2.1 1 1 1 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.7 CCM00244.1 - 0.093 12.1 0.1 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.7 CCM00244.1 - 0.12 11.2 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Med4 PF10018.4 CCM00245.1 - 4.1e-25 88.2 0.0 5.7e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ZZ PF00569.12 CCM00246.1 - 3.1e-16 58.6 61.6 3.4e-07 29.6 2.4 6.1 6 0 0 6 6 6 3 Zinc finger, ZZ type PB1 PF00564.19 CCM00246.1 - 8.1e-13 47.8 0.1 1.8e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Voltage_CLC PF00654.15 CCM00247.1 - 5.9e-85 285.3 28.4 5.9e-85 285.3 19.7 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CCM00247.1 - 8.2e-12 44.7 0.0 2.6e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain Methyltransf_11 PF08241.7 CCM00248.1 - 3.7e-07 30.5 0.0 7.9e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00248.1 - 7e-07 29.8 0.0 9.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM00248.1 - 1.3e-06 28.0 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM00248.1 - 3.4e-05 24.1 0.0 5.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM00248.1 - 0.0032 17.2 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCM00248.1 - 0.032 13.8 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Tmemb_14 PF03647.8 CCM00249.1 - 9.9e-18 64.3 6.4 1.2e-17 64.0 4.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C MtrC PF04211.8 CCM00249.1 - 0.29 10.1 4.4 0.29 10.1 3.0 1.0 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C Methyltransf_28 PF02636.12 CCM00250.1 - 1.4e-36 126.1 0.0 3.3e-36 124.9 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 CCM00250.1 - 0.013 14.5 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 CCM00250.1 - 0.031 14.6 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00250.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCM00250.1 - 0.071 13.5 0.0 0.51 10.8 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain MMS19_N PF14500.1 CCM00251.1 - 8.9e-94 313.6 0.0 3e-92 308.6 0.0 2.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 CCM00251.1 - 3.3e-64 217.1 0.2 1.5e-55 188.6 0.0 3.3 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 CCM00251.1 - 4.3e-06 26.9 2.8 0.00059 20.0 0.1 4.7 4 2 1 5 5 5 1 HEAT repeats Ipi1_N PF12333.3 CCM00251.1 - 0.0028 17.6 0.3 28 4.7 0.0 4.1 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 CCM00251.1 - 0.091 13.2 0.2 0.091 13.2 0.1 4.6 5 1 0 5 5 5 0 HEAT-like repeat HEAT PF02985.17 CCM00251.1 - 1.8 8.8 5.4 60 4.1 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat TSGP1 PF07771.6 CCM00253.1 - 0.54 10.1 5.8 0.63 9.9 4.0 1.1 1 0 0 1 1 1 0 Tick salivary peptide group 1 PRiA4_ORF3 PF07929.6 CCM00254.1 - 4.2e-21 75.1 0.0 7.1e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.13 CCM00254.1 - 1.7e-11 43.7 11.5 2.7e-11 43.1 7.9 1.3 1 0 0 1 1 1 1 MYND finger RRM_1 PF00076.17 CCM00255.1 - 5.2e-29 99.6 1.4 2e-13 49.7 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM00255.1 - 3e-21 75.1 0.2 2.6e-07 30.5 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM00255.1 - 4.7e-13 48.7 0.1 0.00055 19.7 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 CCM00255.1 - 0.15 12.0 0.0 9.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Smg-4/UPF3 family MIP-T3 PF10243.4 CCM00255.1 - 9.5 4.5 13.9 12 4.2 9.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Fis1_TPR_C PF14853.1 CCM00257.1 - 3e-24 84.6 0.8 5e-24 83.9 0.6 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CCM00257.1 - 3.3e-17 61.4 0.0 9.2e-17 60.0 0.0 1.7 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 CCM00257.1 - 0.0024 17.6 0.3 0.0057 16.4 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCM00257.1 - 0.022 14.3 0.8 0.044 13.4 0.6 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 CCM00257.1 - 0.032 14.3 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_M50B PF13398.1 CCM00258.1 - 9.7e-40 136.0 14.6 2.7e-39 134.6 10.1 1.6 1 1 0 1 1 1 1 Peptidase M50B-like DUF3366 PF11846.3 CCM00258.1 - 0.049 13.4 1.0 0.59 9.9 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) Peptidase_M50 PF02163.17 CCM00258.1 - 8.9 5.2 8.6 0.53 9.2 1.4 2.6 2 1 0 2 2 2 0 Peptidase family M50 Histone PF00125.19 CCM00259.1 - 1.8e-26 92.0 0.0 2.2e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCM00259.1 - 1.8e-06 27.8 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FCH PF00611.18 CCM00260.1 - 2.6e-10 40.3 0.7 1e-09 38.4 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 CCM00260.1 - 7.9e-08 32.0 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.16 CCM00260.1 - 0.0021 17.7 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ribonucleas_3_3 PF14622.1 CCM00261.1 - 1.7e-08 34.4 0.0 3.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 CCM00261.1 - 9.4e-07 29.3 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 CCM00261.1 - 0.00016 22.0 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain TPR_1 PF00515.23 CCM00262.1 - 7.3e-22 76.0 5.9 3.9e-07 29.4 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 CCM00262.1 - 7.8e-21 73.4 9.4 6.8e-12 44.8 0.7 3.6 2 1 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 CCM00262.1 - 4.4e-19 66.8 12.4 1.1e-06 28.0 0.2 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCM00262.1 - 4.2e-14 51.7 15.0 3.2e-05 24.1 0.0 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCM00262.1 - 2e-13 49.4 7.2 0.0073 16.4 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCM00262.1 - 2.5e-13 49.7 8.8 1.2e-08 34.7 0.5 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM00262.1 - 5.2e-13 49.2 7.5 2.1e-08 34.6 0.8 4.2 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCM00262.1 - 1.6e-12 47.5 9.4 1.4e-08 34.8 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CCM00262.1 - 1.7e-07 31.2 2.7 0.00019 21.4 0.2 3.5 1 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCM00262.1 - 2.7e-07 29.8 0.9 0.063 13.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCM00262.1 - 5.2e-07 29.4 9.2 0.00025 20.8 0.8 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCM00262.1 - 3.9e-06 26.2 6.7 0.62 9.9 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 CCM00262.1 - 0.0001 22.3 6.8 0.19 11.8 0.2 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCM00262.1 - 0.0023 18.2 2.7 42 4.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 CCM00262.1 - 0.016 15.8 1.4 5.4 7.7 0.1 3.4 2 1 1 3 3 3 0 Sel1 repeat NYD-SP12_N PF15015.1 CCM00262.1 - 0.069 11.3 0.2 0.11 10.7 0.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_10 PF13374.1 CCM00262.1 - 0.17 11.8 18.0 0.26 11.2 0.5 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CCM00262.1 - 0.6 10.0 3.9 8.5 6.3 0.0 4.0 4 1 1 5 5 4 0 MIT (microtubule interacting and transport) domain PRA1 PF03208.14 CCM00263.1 - 4.7e-40 136.4 0.4 5.2e-40 136.2 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF932 PF06067.6 CCM00263.1 - 0.027 13.7 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF3040 PF11239.3 CCM00263.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) PAS PF00989.19 CCM00264.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold Methyltransf_26 PF13659.1 CCM00265.1 - 5.9e-13 48.8 0.0 2.5e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM00265.1 - 1.1e-07 31.5 0.0 4.8e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00265.1 - 1.2e-05 25.8 0.0 2.5e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM00265.1 - 3.3e-05 24.1 0.0 0.00017 21.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CCM00265.1 - 0.0019 17.3 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CCM00265.1 - 0.0083 15.5 0.1 0.02 14.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain AviRa PF11599.3 CCM00265.1 - 0.044 12.7 0.1 0.093 11.7 0.1 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_11 PF08241.7 CCM00265.1 - 0.11 13.0 0.0 0.57 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain SBF PF01758.11 CCM00266.1 - 4.1e-47 160.0 18.8 4.1e-47 160.0 13.0 2.1 3 0 0 3 3 3 1 Sodium Bile acid symporter family adh_short PF00106.20 CCM00267.1 - 4.6e-26 91.7 0.4 6e-26 91.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM00267.1 - 4.8e-26 92.0 0.1 5.7e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM00267.1 - 1.5e-10 41.0 1.7 1.1e-09 38.1 1.2 1.9 1 1 0 1 1 1 1 KR domain Hpre_diP_synt_I PF07456.6 CCM00267.1 - 0.072 12.9 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase component I NAD_binding_8 PF13450.1 CCM00268.1 - 5.5e-14 51.9 0.4 1.7e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCM00268.1 - 9.9e-06 24.6 0.1 1.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM00268.1 - 5.7e-05 22.9 0.0 0.00019 21.2 0.0 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CCM00268.1 - 8.3e-05 22.7 0.3 0.00032 20.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM00268.1 - 0.00036 19.7 0.0 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CCM00268.1 - 0.0026 16.3 0.0 0.0091 14.5 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 CCM00268.1 - 0.0031 16.6 0.0 0.007 15.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCM00268.1 - 0.0032 17.3 0.0 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCM00268.1 - 0.0042 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CCM00268.1 - 0.0064 16.8 0.0 0.25 11.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FKBP_C PF00254.23 CCM00269.1 - 2.8e-29 100.9 0.1 6.3e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Scs3p PF10261.4 CCM00270.1 - 5.2e-41 140.2 4.5 1e-40 139.2 3.1 1.5 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ALAD PF00490.16 CCM00271.1 - 2.7e-119 397.8 0.0 3.3e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pkinase PF00069.20 CCM00272.1 - 4.8e-40 137.3 0.0 6.5e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00272.1 - 3.6e-26 91.7 0.0 5.3e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM00272.1 - 0.0024 17.6 2.1 0.014 15.1 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCM00272.1 - 0.34 9.8 0.0 0.57 9.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.27 CCM00273.1 - 0.14 12.0 0.5 0.41 10.6 0.1 1.9 1 1 1 2 2 2 0 WD domain, G-beta repeat Exo_endo_phos PF03372.18 CCM00274.1 - 1.2e-21 77.8 0.0 1.9e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PPR_2 PF13041.1 CCM00275.1 - 4.9e-07 29.6 0.2 0.012 15.5 0.0 4.7 3 1 1 4 4 4 3 PPR repeat family HD PF01966.17 CCM00278.1 - 1.8e-11 44.1 0.0 4.7e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 HD domain BTB PF00651.26 CCM00279.1 - 0.0027 17.6 0.0 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF4201 PF13870.1 CCM00280.1 - 0.0011 18.4 4.7 0.0011 18.4 3.2 4.7 2 2 2 4 4 4 2 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.4 CCM00280.1 - 0.0078 16.2 8.1 0.0078 16.2 5.6 4.4 2 2 0 4 4 4 1 JNK_SAPK-associated protein-1 HALZ PF02183.13 CCM00280.1 - 0.021 14.5 0.4 0.021 14.5 0.3 6.2 7 1 1 8 8 8 0 Homeobox associated leucine zipper DUF1409 PF07197.7 CCM00280.1 - 0.19 11.7 0.1 0.19 11.7 0.1 5.1 5 2 0 5 5 5 0 Protein of unknown function (DUF1409) WEMBL PF05701.6 CCM00281.1 - 0.041 12.3 19.1 1.2 7.4 13.2 2.2 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DivIC PF04977.10 CCM00281.1 - 3.3 7.2 10.9 5.8 6.4 0.1 3.6 3 1 0 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CCM00281.1 - 7.4 6.3 19.7 1.4 8.6 2.7 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Glyco_hydro_17 PF00332.13 CCM00282.1 - 0.021 13.8 0.0 0.05 12.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Prp19 PF08606.6 CCM00282.1 - 0.021 14.5 8.9 1.8 8.3 0.1 4.2 3 1 1 4 4 4 0 Prp19/Pso4-like NRN1 PF15056.1 CCM00282.1 - 0.031 14.2 0.1 20 5.2 0.0 3.3 2 0 0 2 2 2 0 Neuritin protein family Bestrophin PF01062.16 CCM00282.1 - 6.2 5.6 6.6 2.4 7.0 2.3 1.9 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel Atg14 PF10186.4 CCM00282.1 - 6.3 5.6 36.5 0.026 13.4 2.4 3.5 3 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF717 PF05338.7 CCM00282.1 - 7.7 6.5 8.3 6.2 6.8 0.1 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF717) 3Beta_HSD PF01073.14 CCM00283.1 - 0.026 13.2 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCM00284.1 - 3.2e-15 56.4 1.3 5.4e-15 55.7 0.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM00284.1 - 3.9e-09 36.4 0.5 6.6e-09 35.6 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM00284.1 - 7.2e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 CCM00284.1 - 0.00021 21.3 0.7 0.00046 20.2 0.5 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 CCM00284.1 - 0.00064 19.2 0.3 0.001 18.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DOT1 PF08123.8 CCM00284.1 - 0.0028 16.9 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 NAD_binding_10 PF13460.1 CCM00284.1 - 0.021 14.8 1.9 0.047 13.6 1.3 1.8 1 1 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 CCM00284.1 - 0.15 10.9 0.4 0.25 10.2 0.1 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 CCM00285.1 - 1.2e-29 103.1 0.0 2.1e-29 102.4 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CCM00285.1 - 5.3e-14 52.6 3.1 1.2e-10 41.7 0.1 2.4 1 1 1 2 2 2 2 NADH(P)-binding adh_short PF00106.20 CCM00285.1 - 5.7e-08 32.8 3.9 4e-07 30.1 2.6 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM00285.1 - 6.2e-07 29.2 2.9 7.7e-06 25.6 1.3 2.7 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 CCM00285.1 - 1.1e-06 28.2 0.1 9.4e-06 25.2 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCM00285.1 - 0.0043 16.0 0.1 1 8.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 CCM00285.1 - 0.0074 15.0 0.1 0.027 13.2 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CCM00285.1 - 0.018 13.9 0.1 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 CCM00285.1 - 0.041 13.6 0.1 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Acetyltransf_7 PF13508.1 CCM00286.1 - 4.9e-09 36.2 0.0 1.3e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCM00286.1 - 5e-07 29.8 0.7 2e-06 27.9 0.2 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCM00286.1 - 6.9e-06 25.7 0.8 0.00053 19.6 0.0 2.4 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.19 CCM00286.1 - 7.5e-06 25.8 0.1 3.1e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CCM00286.1 - 0.0016 18.3 0.0 0.0044 16.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCM00286.1 - 0.034 14.0 0.0 0.082 12.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RII_binding_1 PF10522.4 CCM00286.1 - 0.078 13.1 0.2 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 RII binding domain Tnp_DNA_bind PF14706.1 CCM00286.1 - 0.092 12.4 0.5 0.24 11.1 0.4 1.7 1 0 0 1 1 1 0 Transposase DNA-binding Acetyltransf_7 PF13508.1 CCM00287.1 - 5.2e-11 42.5 0.0 1.2e-10 41.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM00287.1 - 1.4e-07 31.4 0.1 4.7e-07 29.7 0.1 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCM00287.1 - 5.2e-05 23.3 0.7 0.0017 18.4 0.3 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCM00287.1 - 0.00045 20.0 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCM00287.1 - 0.00097 18.8 0.1 0.0023 17.6 0.1 1.7 1 1 0 1 1 1 1 FR47-like protein RII_binding_1 PF10522.4 CCM00287.1 - 0.091 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 RII binding domain Acetyltransf_CG PF14542.1 CCM00287.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Metallophos PF00149.23 CCM00290.1 - 5.5e-33 114.0 0.0 6.7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCM00290.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain ABC_tran PF00005.22 CCM00291.1 - 2e-49 167.4 0.1 1.5e-24 86.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 CCM00291.1 - 2.7e-20 72.0 4.5 2.7e-20 72.0 3.1 2.1 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 CCM00291.1 - 7.2e-19 68.8 3.1 9.2e-05 22.5 0.0 4.5 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 CCM00291.1 - 2.5e-10 39.9 2.3 0.055 12.6 0.4 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCM00291.1 - 2e-09 36.8 0.1 0.00071 19.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CCM00291.1 - 3.1e-09 37.4 8.9 0.00088 19.6 0.0 3.9 5 0 0 5 5 3 3 AAA domain AAA_16 PF13191.1 CCM00291.1 - 7.9e-08 32.4 0.0 0.0014 18.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 CCM00291.1 - 5.7e-07 28.9 4.7 0.22 10.5 0.0 4.7 3 1 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 CCM00291.1 - 9e-07 29.7 1.3 0.081 13.7 0.1 3.3 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 CCM00291.1 - 9.1e-07 29.3 0.0 0.067 13.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 CCM00291.1 - 5.1e-06 25.7 0.0 0.0015 17.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 CCM00291.1 - 5.5e-06 26.1 0.1 0.085 12.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 CCM00291.1 - 1.1e-05 24.9 0.2 0.35 10.2 0.0 3.3 3 1 0 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 CCM00291.1 - 1.6e-05 24.8 0.2 0.0095 15.8 0.3 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCM00291.1 - 1.8e-05 24.8 0.8 0.52 10.4 0.0 3.9 3 2 0 3 3 2 2 AAA domain AAA_25 PF13481.1 CCM00291.1 - 1.8e-05 24.1 0.0 0.85 8.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CCM00291.1 - 3.7e-05 24.0 1.3 0.53 10.5 0.0 3.4 4 0 0 4 4 3 2 AAA domain FtsK_SpoIIIE PF01580.13 CCM00291.1 - 6.6e-05 22.4 0.3 0.32 10.4 0.0 2.8 3 1 0 3 3 2 2 FtsK/SpoIIIE family MobB PF03205.9 CCM00291.1 - 0.00013 21.6 1.5 0.27 10.9 0.0 3.5 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CCM00291.1 - 0.00028 21.0 1.9 2.9 8.1 0.0 3.5 3 0 0 3 3 3 1 RNA helicase DUF87 PF01935.12 CCM00291.1 - 0.0006 19.7 3.0 0.69 9.6 0.0 4.0 4 1 1 5 5 5 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 CCM00291.1 - 0.00065 19.5 9.4 0.12 12.1 0.5 4.1 2 2 1 3 3 3 2 Dynamin family SbcCD_C PF13558.1 CCM00291.1 - 0.0012 18.7 1.0 0.56 10.1 0.0 3.3 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CCM00291.1 - 0.0016 18.3 0.0 4.3 7.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 CCM00291.1 - 0.0017 18.2 0.0 9.8 6.0 0.0 4.4 5 0 0 5 5 4 0 AAA domain AAA_30 PF13604.1 CCM00291.1 - 0.0018 17.9 0.0 0.21 11.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCM00291.1 - 0.0032 17.1 0.0 2.6 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CCM00291.1 - 0.004 17.3 0.1 4.2 7.5 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CCM00291.1 - 0.0042 17.0 0.0 0.62 10.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 CCM00291.1 - 0.0074 15.5 0.0 0.061 12.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP-synt_ab PF00006.20 CCM00291.1 - 0.01 15.3 0.0 0.6 9.5 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.13 CCM00291.1 - 0.011 14.8 0.1 3.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Septin DAP3 PF10236.4 CCM00291.1 - 0.011 14.6 1.1 3.5 6.4 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 CCM00291.1 - 0.015 14.1 0.0 4.8 5.9 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain KAP_NTPase PF07693.9 CCM00291.1 - 0.016 14.2 0.2 2.6 6.9 0.0 2.7 2 1 0 2 2 2 0 KAP family P-loop domain T2SE PF00437.15 CCM00291.1 - 0.035 13.0 0.1 1.5 7.6 0.1 2.5 2 1 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 CCM00291.1 - 0.038 13.5 0.0 6.4 6.2 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 CCM00291.1 - 0.054 12.9 0.6 8.2 5.8 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain LPP PF04728.8 CCM00291.1 - 0.063 13.0 0.1 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 Lipoprotein leucine-zipper AAA_19 PF13245.1 CCM00291.1 - 0.091 12.5 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 CCM00291.1 - 0.19 11.4 5.2 2.9 7.5 0.1 3.6 5 0 0 5 5 3 0 NTPase Ribosomal_L1 PF00687.16 CCM00292.1 - 1e-50 172.1 2.9 1.2e-50 171.8 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF647 PF04884.9 CCM00292.1 - 0.076 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis Clathrin PF00637.15 CCM00293.1 - 4.3e-23 81.5 0.1 6.5e-22 77.6 0.0 2.8 4 0 0 4 4 4 1 Region in Clathrin and VPS Vps39_1 PF10366.4 CCM00293.1 - 0.0001 22.2 0.2 0.0021 18.0 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.27 CCM00293.1 - 0.013 15.3 0.3 0.3 11.0 0.1 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Ribosomal_L7Ae PF01248.21 CCM00294.1 - 1.6e-27 94.8 3.0 2e-27 94.5 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.27 CCM00295.1 - 1e-21 75.9 7.2 1.6e-09 37.3 0.5 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 CCM00295.1 - 0.008 14.3 0.2 0.011 13.9 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 GST_N PF02798.15 CCM00296.1 - 1e-17 64.0 0.0 7.7e-17 61.2 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCM00296.1 - 4.4e-14 52.2 0.1 9.8e-14 51.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCM00296.1 - 2.1e-13 50.2 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM00296.1 - 2.1e-13 50.0 0.0 3.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM00296.1 - 5e-07 29.5 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCM00296.1 - 5.5e-05 23.5 0.1 8.8e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 CCM00296.1 - 0.0042 17.4 0.1 0.014 15.7 0.0 1.8 2 0 0 2 2 2 1 MetRS-N binding domain DUF2892 PF11127.3 CCM00297.1 - 5.5 6.8 7.1 2.6 7.9 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) adh_short PF00106.20 CCM00298.1 - 9.4e-08 32.1 0.0 1.2e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Hydantoinase_A PF01968.13 CCM00300.1 - 7.3e-78 261.6 0.0 1.1e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CCM00300.1 - 1.3e-52 177.8 0.1 2.1e-49 167.4 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region NIF PF03031.13 CCM00301.1 - 1.7e-13 50.5 0.0 9.5e-12 44.8 0.0 2.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RNase_PH PF01138.16 CCM00302.1 - 1.5e-18 67.4 0.0 2.3e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCM00302.1 - 1.3e-07 31.4 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNA_pol_Rpb4 PF03874.11 CCM00302.1 - 0.063 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb4 Trm112p PF03966.11 CCM00303.1 - 1.7e-20 73.1 0.0 2e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-NADH-PPase PF09297.6 CCM00303.1 - 0.002 17.6 0.1 0.0035 16.8 0.1 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 CCM00303.1 - 0.0072 15.4 0.2 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CCM00303.1 - 0.013 14.9 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 CCM00303.1 - 0.025 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain UPF0547 PF10571.4 CCM00303.1 - 0.029 14.0 0.2 0.05 13.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 TF_Zn_Ribbon PF08271.7 CCM00303.1 - 0.059 12.7 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.7 CCM00303.1 - 0.089 12.5 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon ADK_lid PF05191.9 CCM00303.1 - 0.13 11.9 0.4 0.24 11.0 0.3 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid AhpC-TSA PF00578.16 CCM00304.1 - 1.5e-38 131.2 0.0 2.4e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 CCM00304.1 - 7.3e-14 51.1 0.0 1.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 CCM00304.1 - 7.8e-14 51.4 0.0 1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin Peptidase_M48 PF01435.13 CCM00306.1 - 1.1e-20 74.1 0.0 1.8e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 CCM00306.1 - 0.041 13.0 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain LamB_YcsF PF03746.11 CCM00307.1 - 4.3e-24 84.9 0.0 4.9e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CPSase_L_chain PF00289.17 CCM00308.1 - 9.5e-34 115.8 0.0 1.7e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D2 PF02786.12 CCM00308.1 - 9.1e-16 57.7 0.1 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 CCM00308.1 - 3.2e-07 29.4 0.0 4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CCM00308.1 - 8.4e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 CCM00308.1 - 0.00015 21.1 0.0 0.0093 15.3 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 CCM00308.1 - 0.00086 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCM00308.1 - 0.003 16.9 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 CCM00308.1 - 0.084 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain AHS2 PF02626.10 CCM00309.1 - 3.1e-82 275.9 0.0 4.6e-82 275.3 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 Biotin_carb_C PF02785.14 CCM00309.1 - 1.9e-31 108.2 0.0 3.3e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain AHS1 PF02682.11 CCM00309.1 - 1.9e-28 99.3 0.0 1.3e-26 93.3 0.0 2.3 1 1 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_D2 PF02786.12 CCM00309.1 - 5.2e-16 58.5 0.0 1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_lipoyl PF00364.17 CCM00309.1 - 5.6e-06 25.9 2.0 2.1e-05 24.0 1.4 1.9 1 1 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CCM00309.1 - 0.2 11.3 0.6 3.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like FAD_binding_3 PF01494.14 CCM00310.1 - 5.9e-17 61.7 0.0 1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCM00310.1 - 7.7e-08 32.2 0.7 2.5e-07 30.6 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CCM00310.1 - 8.5e-06 24.9 0.0 4.4e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein F-box-like PF12937.2 CCM00310.1 - 3.6e-05 23.4 0.0 7.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like Trp_halogenase PF04820.9 CCM00310.1 - 4.6e-05 22.2 1.1 0.03 12.9 0.2 2.6 2 1 1 3 3 3 2 Tryptophan halogenase DAO PF01266.19 CCM00310.1 - 5.1e-05 22.3 1.9 0.00013 20.9 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCM00310.1 - 0.00047 19.1 2.2 0.00077 18.4 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCM00310.1 - 0.00075 19.4 0.1 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCM00310.1 - 0.0041 16.2 0.4 0.0095 15.0 0.2 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 CCM00310.1 - 0.01 14.9 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 CCM00310.1 - 0.025 13.6 0.1 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCM00310.1 - 0.027 14.8 0.1 0.066 13.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCM00310.1 - 0.078 12.7 0.2 0.46 10.2 0.2 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 CCM00310.1 - 0.11 10.9 1.0 0.18 10.2 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 CCM00310.1 - 0.12 11.2 2.0 0.18 10.5 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 CCM00310.1 - 0.29 9.9 0.0 0.43 9.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.13 CCM00310.1 - 0.54 9.8 0.5 0.96 9.0 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CCM00310.1 - 0.57 9.6 1.6 0.95 8.8 1.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PRELI PF04707.9 CCM00312.1 - 4e-37 127.2 0.0 5.6e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family Phage_T4_Ndd PF06591.6 CCM00312.1 - 0.0025 17.3 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 T4-like phage nuclear disruption protein (Ndd) Lactamase_B_2 PF12706.2 CCM00313.1 - 2.4e-13 50.0 0.1 1e-12 48.0 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCM00313.1 - 1.2e-11 44.6 0.5 1.9e-11 43.9 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 CCM00313.1 - 0.044 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MMR_HSR1 PF01926.18 CCM00314.1 - 2e-18 66.4 0.0 3.5e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 CCM00314.1 - 4.8e-18 64.7 0.0 1.8e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CCM00314.1 - 4.4e-11 42.3 0.0 7.9e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCM00314.1 - 0.00038 20.9 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 CCM00314.1 - 0.0018 18.1 0.1 0.073 12.8 0.0 2.4 1 1 1 2 2 2 1 Dynamin family Pkinase PF00069.20 CCM00315.1 - 3.5e-64 216.4 0.0 6.6e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00315.1 - 3e-36 124.8 0.1 8.8e-35 120.0 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM00315.1 - 3.1e-08 32.9 0.0 1.4e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCM00315.1 - 0.0014 18.3 0.2 0.0053 16.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCM00315.1 - 0.0053 15.6 0.1 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RPE65 PF03055.10 CCM00316.1 - 1e-108 364.0 0.0 1.5e-108 363.4 0.0 1.3 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MFS_1 PF07690.11 CCM00317.1 - 2.3e-40 138.3 41.1 2.3e-40 138.3 28.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 CCM00317.1 - 0.00032 18.9 3.3 0.00032 18.9 2.3 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector PRELI PF04707.9 CCM00318.1 - 1.2e-23 83.4 0.0 2.1e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 PRELI-like family B-block_TFIIIC PF04182.7 CCM00318.1 - 3.3e-13 49.2 0.4 4.5e-08 32.8 0.0 3.7 3 1 1 4 4 4 2 B-block binding subunit of TFIIIC MarR_2 PF12802.2 CCM00318.1 - 3.3e-06 26.6 1.2 0.089 12.4 0.0 4.0 4 0 0 4 4 4 2 MarR family HTH_27 PF13463.1 CCM00318.1 - 3.6e-05 23.9 0.0 0.022 15.0 0.0 3.6 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_24 PF13412.1 CCM00318.1 - 0.00013 21.2 0.0 0.7 9.3 0.0 3.8 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding ABC_membrane_2 PF06472.10 CCM00319.1 - 9.7e-54 182.3 1.1 3.9e-51 173.8 0.8 2.2 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCM00319.1 - 1.7e-17 63.9 0.0 3.7e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCM00319.1 - 0.00026 21.0 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CCM00319.1 - 0.015 15.6 0.4 0.033 14.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CCM00319.1 - 0.017 15.0 0.1 0.086 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 CCM00319.1 - 0.031 13.8 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 CCM00319.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF815 PF05673.8 CCM00319.1 - 0.085 11.7 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF258 PF03193.11 CCM00319.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NT5C PF06941.7 CCM00320.1 - 3.5e-12 46.2 0.1 2.3e-11 43.5 0.0 2.1 3 0 0 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) LNS2 PF08235.8 CCM00320.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) RINT1_TIP1 PF04437.8 CCM00322.1 - 9.9e-79 265.1 0.0 2.6e-78 263.7 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family MCM PF00493.18 CCM00323.1 - 9.9e-126 419.0 0.0 1.4e-125 418.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCM00323.1 - 1.5e-23 83.6 0.0 3.6e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCM00323.1 - 5.2e-08 32.2 0.0 8.7e-07 28.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCM00323.1 - 0.0019 17.7 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCM00323.1 - 0.0084 15.5 0.1 0.034 13.6 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain WD40 PF00400.27 CCM00325.1 - 2.7e-34 115.8 0.5 4.6e-09 35.8 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 CCM00325.1 - 0.0047 16.4 0.0 0.01 15.3 0.0 1.5 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 CCM00325.1 - 0.12 10.4 0.5 1.2 7.2 0.4 2.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 NESP55 PF06390.7 CCM00325.1 - 0.27 10.6 2.5 0.42 9.9 1.7 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Myb_DNA-bind_6 PF13921.1 CCM00327.1 - 1.8e-34 117.6 2.1 2.2e-16 59.7 0.1 3.7 2 1 2 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCM00327.1 - 2.1e-32 110.8 4.9 1.2e-13 50.8 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 CCM00327.1 - 0.0019 18.0 2.3 7.9 6.4 0.1 3.4 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Mito_carr PF00153.22 CCM00328.1 - 1.5e-15 56.6 0.0 1.5e-05 24.6 0.0 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Spc7 PF08317.6 CCM00329.1 - 3.6e-44 150.7 7.5 5.5e-44 150.1 5.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CCM00329.1 - 7.1e-05 22.1 1.0 7.1e-05 22.1 0.7 1.8 2 0 0 2 2 2 1 Reovirus sigma C capsid protein FUSC PF04632.7 CCM00329.1 - 0.25 9.7 3.1 0.4 9.0 2.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 CCM00329.1 - 1.1 7.6 7.0 1.6 7.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PspA_IM30 PF04012.7 CCM00329.1 - 2.4 7.4 18.5 5.7 6.2 12.8 1.6 1 1 0 1 1 1 0 PspA/IM30 family Fib_alpha PF08702.5 CCM00329.1 - 4.6 7.3 9.8 6 6.9 5.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 CCM00329.1 - 5.7 6.7 7.4 3 7.6 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6 PF04111.7 CCM00329.1 - 5.8 5.8 15.4 12 4.8 10.7 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinesin PF00225.18 CCM00330.1 - 2.7e-83 279.4 0.3 2.1e-82 276.5 0.0 2.4 2 1 0 2 2 2 1 Kinesin motor domain C2 PF00168.25 CCM00331.1 - 1.7e-15 56.6 0.0 2.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 C2 domain PID_2 PF14719.1 CCM00331.1 - 7.5e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) C2 PF00168.25 CCM00332.1 - 5.3e-47 157.5 0.1 1.2e-14 53.9 0.0 4.5 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 CCM00332.1 - 0.16 12.1 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) adh_short PF00106.20 CCM00333.1 - 2.1e-13 50.5 0.0 2.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM00333.1 - 3.4e-09 36.6 0.1 4.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM00333.1 - 0.004 16.9 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.1 CCM00333.1 - 0.14 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3373 PF11853.3 CCM00334.1 - 2.3 6.6 4.8 3.5 6.0 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DIE2_ALG10 PF04922.7 CCM00335.1 - 2.2e-96 323.1 6.8 3e-96 322.7 4.7 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family Methyltransf_26 PF13659.1 CCM00336.1 - 7.5e-07 29.1 0.0 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCM00336.1 - 6.2e-05 22.4 0.0 8.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TauD PF02668.11 CCM00337.1 - 2.8e-50 171.4 0.6 3.4e-50 171.1 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OPT PF03169.10 CCM00338.1 - 6.6e-194 645.8 59.2 7.7e-194 645.6 41.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Prp19 PF08606.6 CCM00339.1 - 1.1e-31 108.3 1.0 2.2e-31 107.3 0.7 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 CCM00339.1 - 7.2e-19 66.9 0.0 6.7e-07 28.9 0.0 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat U-box PF04564.10 CCM00339.1 - 1.7e-05 24.6 0.0 7.5e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 CCM00339.1 - 0.0016 17.9 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3312 PF11768.3 CCM00339.1 - 0.0026 16.0 0.0 0.0048 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Rtf2 PF04641.7 CCM00339.1 - 0.0074 15.5 0.2 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger Uds1 PF15456.1 CCM00339.1 - 0.051 13.5 0.4 0.092 12.7 0.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation TPR_11 PF13414.1 CCM00340.1 - 6.3e-25 86.6 2.6 3.9e-18 64.8 1.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCM00340.1 - 8.2e-24 82.1 0.0 3.1e-07 29.7 0.0 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCM00340.1 - 1.6e-19 68.1 0.1 1.6e-06 27.5 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCM00340.1 - 7.3e-12 44.5 0.3 0.00044 20.2 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCM00340.1 - 4.8e-11 41.6 0.0 0.0046 16.6 0.0 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCM00340.1 - 9.9e-10 37.4 0.0 0.0013 18.3 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM00340.1 - 1.2e-09 37.9 0.1 0.0048 17.4 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM00340.1 - 3.4e-09 37.1 0.6 0.00018 22.0 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM00340.1 - 1.9e-08 34.1 1.8 1e-05 25.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCM00340.1 - 2.4e-06 27.2 0.1 0.00014 21.6 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCM00340.1 - 2.6e-05 24.4 0.3 0.0063 16.8 0.2 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CCM00340.1 - 0.0001 22.3 1.0 0.0076 16.3 0.7 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCM00340.1 - 0.019 15.4 0.0 1.6 9.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 CCM00340.1 - 0.04 14.2 0.1 0.79 10.0 0.0 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain NUDIX PF00293.23 CCM00341.1 - 8.9e-09 35.0 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.20 CCM00342.1 - 1e-53 182.1 0.0 1.4e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00342.1 - 2.9e-32 111.7 0.0 4.6e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM00342.1 - 0.001 18.0 0.0 0.0027 16.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCM00342.1 - 0.055 13.1 0.2 0.055 13.1 0.1 2.7 3 1 1 4 4 4 0 Phosphotransferase enzyme family RRM_1 PF00076.17 CCM00343.1 - 2.3e-14 52.7 0.1 3.4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM00343.1 - 2.4e-09 37.0 0.0 3.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM00343.1 - 3.6e-08 33.1 0.1 6.5e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 CCM00343.1 - 4.1e-08 32.7 3.5 7.1e-08 32.0 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCM00343.1 - 0.00042 19.9 0.5 0.00098 18.8 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CCM00343.1 - 0.0021 17.6 0.1 0.0043 16.6 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 CCM00343.1 - 0.011 15.1 2.3 0.038 13.4 1.6 1.9 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Pkinase PF00069.20 CCM00344.1 - 8.5e-42 143.0 0.0 4.8e-23 81.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00344.1 - 7.7e-10 38.2 0.0 2.5e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Septin PF00735.13 CCM00344.1 - 0.1 11.5 0.1 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Septin Pox_ser-thr_kin PF05445.6 CCM00344.1 - 0.23 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UCR_TM PF02921.9 CCM00345.1 - 2.5e-17 62.8 0.6 4.7e-17 61.9 0.4 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CCM00345.1 - 5.1e-17 61.2 0.0 8.8e-17 60.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF4078 PF13300.1 CCM00345.1 - 0.08 13.0 0.7 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) GDPD PF03009.12 CCM00346.1 - 1.8e-31 109.5 0.0 2.2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CCM00346.1 - 1.2e-05 25.3 0.2 0.00021 21.3 0.1 2.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Arabinose_Isome PF02610.10 CCM00346.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 L-arabinose isomerase bZIP_2 PF07716.10 CCM00347.1 - 1.5e-09 37.5 7.5 3.2e-09 36.4 5.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CCM00347.1 - 1.4e-05 24.9 7.8 0.00016 21.5 5.4 2.2 1 1 0 1 1 1 1 bZIP transcription factor DUF2216 PF10226.4 CCM00347.1 - 0.0025 17.3 1.6 0.0035 16.8 0.3 1.7 1 1 1 2 2 2 1 Uncharacterized conserved proteins (DUF2216) Shugoshin_N PF07558.6 CCM00347.1 - 0.0034 17.0 0.1 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF2205 PF10224.4 CCM00347.1 - 0.0092 15.5 0.2 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) bZIP_Maf PF03131.12 CCM00347.1 - 0.018 15.3 1.3 0.038 14.2 0.9 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.13 CCM00347.1 - 0.071 13.0 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family CHRD PF07452.7 CCM00347.1 - 0.11 13.1 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 CHRD domain PAT1 PF09770.4 CCM00347.1 - 1.8 6.6 9.4 2.1 6.5 6.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NPL4 PF05021.10 CCM00348.1 - 3e-95 318.9 0.0 3.6e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CCM00348.1 - 4.3e-44 149.7 0.0 6.7e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region PIF1 PF05970.9 CCM00349.1 - 5.8e-53 180.1 0.1 4.8e-19 68.5 0.0 3.1 2 1 1 3 3 3 3 PIF1-like helicase Cauli_VI PF01693.11 CCM00349.1 - 3.8e-13 49.2 0.5 8.5e-13 48.1 0.3 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_30 PF13604.1 CCM00349.1 - 2.1e-09 37.2 0.0 1.5e-08 34.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM00349.1 - 0.00017 21.2 1.3 0.00031 20.4 0.2 2.0 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 CCM00349.1 - 0.00023 21.2 0.1 0.00082 19.4 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 CCM00349.1 - 0.00027 21.0 0.1 0.00072 19.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM00349.1 - 0.00036 20.5 0.1 0.0008 19.4 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.9 CCM00349.1 - 0.0011 16.8 1.1 0.0017 16.2 0.1 1.6 2 0 0 2 2 2 1 Helicase PhoH PF02562.11 CCM00349.1 - 0.002 17.3 0.0 0.0058 15.8 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.13 CCM00349.1 - 0.0094 15.4 2.3 2.6 7.5 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 CCM00349.1 - 0.01 14.4 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 CCM00349.1 - 0.014 15.7 0.1 0.044 14.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 CCM00349.1 - 0.044 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 CCM00349.1 - 0.067 12.1 0.1 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 CCM00349.1 - 0.092 12.4 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CCM00349.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain Pkinase PF00069.20 CCM00350.1 - 0.019 14.0 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RhoGAP PF00620.22 CCM00351.1 - 1.4e-43 148.1 0.3 3e-43 147.0 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 CCM00351.1 - 1.4e-05 25.1 0.1 6.3e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Rad51 PF08423.6 CCM00352.1 - 5.5e-132 438.3 0.0 6.9e-132 438.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CCM00352.1 - 7.8e-13 48.2 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 CCM00352.1 - 8.1e-11 41.9 0.3 2.1e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 CCM00352.1 - 1.6e-09 37.3 0.0 2.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CCM00352.1 - 4.8e-06 25.8 0.0 9.6e-06 24.8 0.0 1.5 1 0 0 1 1 1 1 KaiC HHH PF00633.18 CCM00352.1 - 0.016 14.8 0.1 0.054 13.2 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif PAXNEB PF05625.6 CCM00352.1 - 0.042 12.6 0.0 0.084 11.6 0.0 1.4 1 0 0 1 1 1 0 PAXNEB protein 2-Hacid_dh_C PF02826.14 CCM00353.1 - 3.4e-51 172.9 0.0 1.1e-50 171.2 0.0 1.8 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCM00353.1 - 5.6e-33 113.2 0.0 7.8e-33 112.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCM00353.1 - 0.00086 19.1 0.1 0.003 17.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CCM00353.1 - 0.0092 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 CCM00353.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain His_biosynth PF00977.16 CCM00354.1 - 2e-46 158.1 0.4 2.1e-44 151.5 0.3 2.5 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 CCM00354.1 - 4.3e-28 98.0 0.0 7.1e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CCM00354.1 - 1.6e-08 34.2 0.0 3.3e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 CCM00354.1 - 6.2e-06 25.9 0.0 0.00075 19.1 0.0 2.4 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 CCM00354.1 - 0.0086 15.5 0.2 0.4 10.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 Salt_tol_Pase PF09506.5 CCM00354.1 - 0.14 10.6 0.0 0.26 9.8 0.0 1.4 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Pal1 PF08316.6 CCM00355.1 - 1.1e-15 58.3 0.3 1.1e-15 58.3 0.2 2.6 2 2 0 2 2 2 1 Pal1 cell morphology protein SOG2 PF10428.4 CCM00355.1 - 0.99 7.9 6.4 0.2 10.3 0.7 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein Dak1 PF02733.12 CCM00356.1 - 1.2e-98 329.6 1.8 7.5e-85 284.3 0.7 2.9 2 1 0 2 2 2 2 Dak1 domain Dak2 PF02734.12 CCM00356.1 - 4.5e-35 120.8 4.7 6.8e-23 81.2 0.2 2.3 2 0 0 2 2 2 2 DAK2 domain UCH PF00443.24 CCM00357.1 - 2e-80 269.7 0.0 3.5e-80 268.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM00357.1 - 2.9e-19 69.6 0.0 8.1e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CCM00357.1 - 2.4e-12 47.1 1.4 6e-12 45.8 1.0 1.8 1 0 0 1 1 1 1 DUSP domain DUF4479 PF14794.1 CCM00357.1 - 0.047 13.2 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) USP7_C2 PF14533.1 CCM00357.1 - 0.077 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF1712 PF08217.6 CCM00358.1 - 4.3e-19 68.2 0.0 6e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Tim17 PF02466.14 CCM00359.1 - 1.6e-25 89.6 4.1 2e-25 89.3 2.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1688 PF07958.6 CCM00360.1 - 5.7e-163 542.3 0.0 6.8e-163 542.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Cytochrom_C1 PF02167.10 CCM00362.1 - 4.9e-85 284.6 0.0 6e-85 284.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CCM00362.1 - 0.00062 19.8 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CCM00362.1 - 0.012 16.3 0.0 0.033 15.0 0.0 1.7 2 0 0 2 2 2 0 Cytochrome c SAC3_GANP PF03399.11 CCM00363.1 - 1.7e-57 194.3 1.1 3.8e-57 193.1 0.8 1.6 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCM00363.1 - 1.5e-07 31.2 0.1 7.2e-07 29.0 0.0 2.1 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 DUF1215 PF06744.7 CCM00363.1 - 0.035 13.7 0.8 0.2 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1215) tRNA_int_endo PF01974.12 CCM00364.1 - 2.1e-13 49.8 0.0 4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 CCM00364.1 - 2.7e-05 23.6 0.0 0.00053 19.4 0.0 2.2 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Nop25 PF09805.4 CCM00364.1 - 4.7 7.2 8.0 7.4 6.6 5.5 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) WD40 PF00400.27 CCM00365.1 - 1.5e-15 56.3 7.6 2.6e-06 27.0 0.0 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat Aminotran_5 PF00266.14 CCM00366.1 - 4.1e-22 78.4 0.0 5.2e-21 74.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V RRM_DME PF15628.1 CCM00366.1 - 0.0088 15.7 0.0 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 RRM in Demeter NIR_SIR PF01077.17 CCM00367.1 - 1.3e-51 174.1 0.1 6.8e-45 152.2 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 CCM00367.1 - 2.6e-32 110.2 0.0 3.8e-15 55.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 CCM00367.1 - 4.4e-29 101.3 0.0 1.1e-28 99.9 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 CCM00367.1 - 0.041 13.4 0.2 0.087 12.3 0.1 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.2 CCM00367.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Ribosomal_L7Ae PF01248.21 CCM00368.1 - 3.3e-23 81.0 0.0 3.9e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Actin PF00022.14 CCM00369.1 - 5.2e-31 107.4 0.0 1.5e-30 105.9 0.0 1.6 1 1 0 1 1 1 1 Actin MDMPI_N PF11716.3 CCM00369.1 - 0.27 11.6 4.4 0.27 11.6 1.3 2.2 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Prenyltrans_2 PF13249.1 CCM00370.1 - 5.3e-35 120.2 0.1 2.9e-16 59.8 0.1 5.0 2 2 3 5 5 5 5 Prenyltransferase-like Prenyltrans PF00432.16 CCM00370.1 - 1.1e-32 111.2 10.2 2.8e-10 39.5 0.2 6.5 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CCM00370.1 - 1.3e-23 83.1 0.7 1.7e-10 40.9 0.1 6.2 3 2 4 7 7 7 5 Prenyltransferase-like Pec_lyase PF09492.5 CCM00370.1 - 1.1e-06 28.0 0.1 0.2 10.7 0.0 4.7 2 1 3 5 5 5 2 Pectic acid lyase PMM PF03332.8 CCM00372.1 - 5.6e-104 346.5 0.6 6.5e-104 346.2 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 CCM00372.1 - 0.0026 17.0 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 CCM00372.1 - 0.0079 15.7 0.0 0.037 13.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_4 PF13637.1 CCM00373.1 - 0.00038 20.8 0.0 0.00072 20.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCM00373.1 - 0.0016 18.6 0.0 0.0049 17.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM00373.1 - 0.0059 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CCM00373.1 - 0.02 15.1 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DNA_pol_B PF00136.16 CCM00374.1 - 6.2e-144 480.2 0.5 9.3e-144 479.6 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCM00374.1 - 6.3e-76 255.3 0.0 1.2e-75 254.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCM00374.1 - 1.8e-22 79.0 7.6 1.8e-22 79.0 5.2 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 CCM00374.1 - 0.0023 17.4 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 CCM00374.1 - 0.0038 15.9 1.2 0.018 13.7 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 CCM00374.1 - 0.017 14.8 0.0 0.052 13.3 0.0 2.0 1 1 0 1 1 1 0 RNase_H superfamily DUF1476 PF07345.6 CCM00374.1 - 0.07 13.3 0.2 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) C1_1 PF00130.17 CCM00374.1 - 5.1 6.9 8.4 17 5.2 3.2 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAUB PF08164.7 CCM00375.1 - 3.8e-26 91.0 0.0 1.6e-25 88.9 0.0 2.2 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 CCM00375.1 - 1.5e-23 83.4 1.1 1.5e-23 83.4 0.8 2.8 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor PX PF00787.19 CCM00377.1 - 4.1e-22 78.1 0.5 5.1e-21 74.5 0.0 2.8 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 CCM00377.1 - 0.00026 20.3 2.7 0.00026 20.3 1.8 2.1 2 0 0 2 2 2 1 Vps5 C terminal like DUF4391 PF14335.1 CCM00377.1 - 0.16 11.3 7.9 0.023 14.0 2.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) GreA_GreB_N PF03449.10 CCM00377.1 - 0.19 11.7 10.6 0.078 13.0 2.2 2.7 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Sec8_exocyst PF04048.9 CCM00377.1 - 0.46 10.1 8.5 5.2 6.7 1.8 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain FliD_N PF02465.13 CCM00377.1 - 0.54 10.6 7.8 0.21 11.9 1.3 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF106 PF01956.11 CCM00377.1 - 1.1 8.7 2.4 3 7.3 1.7 1.7 1 0 0 1 1 1 0 Integral membrane protein DUF106 CALCOCO1 PF07888.6 CCM00378.1 - 0.0014 16.9 1.6 0.0014 16.9 1.1 1.9 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like ApoL PF05461.6 CCM00378.1 - 0.011 15.0 0.7 0.011 15.0 0.5 1.7 2 0 0 2 2 2 0 Apolipoprotein L FH2 PF02181.18 CCM00378.1 - 0.025 13.4 6.6 0.75 8.6 0.1 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain GAS PF13851.1 CCM00378.1 - 0.15 11.2 13.3 0.12 11.5 4.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 CCM00378.1 - 0.17 11.2 13.1 0.26 10.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.6 CCM00378.1 - 0.19 10.3 11.1 0.68 8.5 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CCM00378.1 - 0.23 10.6 4.0 0.48 9.5 1.2 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 CCM00378.1 - 0.23 11.0 14.7 0.44 10.1 6.0 2.1 2 0 0 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 CCM00378.1 - 0.31 10.8 15.0 0.43 10.4 5.7 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HisKA PF00512.20 CCM00378.1 - 0.79 9.7 7.2 4.2 7.4 3.8 2.8 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Atg14 PF10186.4 CCM00378.1 - 1.5 7.6 9.3 1.6 7.6 2.3 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CCM00378.1 - 1.6 7.7 13.6 0.25 10.3 4.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 RF-1 PF00472.15 CCM00378.1 - 5 6.9 9.5 17 5.2 0.9 3.0 2 1 1 3 3 3 0 RF-1 domain Uds1 PF15456.1 CCM00378.1 - 5.5 6.9 14.2 13 5.8 5.4 2.3 2 0 0 2 2 2 0 Up-regulated During Septation DUF1771 PF08590.5 CCM00379.1 - 4.5e-13 49.0 8.6 1e-12 47.8 6.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 CCM00379.1 - 1.7e-09 37.1 7.9 4.2e-06 26.2 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 CCM00379.1 - 0.00022 21.3 0.0 0.00056 20.0 0.0 1.7 1 0 0 1 1 1 1 Smr domain HBS1_N PF08938.5 CCM00379.1 - 0.11 12.5 0.3 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 HBS1 N-terminus zf-C3H1 PF10650.4 CCM00379.1 - 0.22 11.0 2.5 10 5.6 0.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH_2 PF14608.1 CCM00379.1 - 1.4 9.0 7.1 0.66 10.0 0.6 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Fungal_trans PF04082.13 CCM00380.1 - 2.1e-14 53.0 2.1 3.5e-14 52.2 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cation_efflux PF01545.16 CCM00381.1 - 1.9e-59 201.1 2.9 1.9e-59 201.1 2.0 1.9 2 0 0 2 2 2 1 Cation efflux family CASP_C PF08172.7 CCM00381.1 - 0.12 11.3 0.1 0.26 10.2 0.1 1.4 1 0 0 1 1 1 0 CASP C terminal Rcd1 PF04078.8 CCM00382.1 - 6.6e-129 428.3 3.1 7.7e-129 428.1 2.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PH PF00169.24 CCM00383.1 - 1.7e-06 28.1 0.0 5.2e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CCM00383.1 - 0.23 11.6 0.0 0.23 11.6 0.0 3.0 2 1 0 3 3 3 0 Pleckstrin homology domain DUF572 PF04502.8 CCM00383.1 - 5.2 6.1 27.9 11 5.0 19.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) PDCD2_C PF04194.8 CCM00384.1 - 3.1e-32 111.4 0.0 8.8e-32 109.9 0.0 1.8 1 1 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Fungal_trans PF04082.13 CCM00385.1 - 2.2e-20 72.6 0.6 4.6e-20 71.5 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Paramyxo_NS_C PF02725.9 CCM00385.1 - 0.023 14.3 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Non-structural protein C Ras PF00071.17 CCM00386.1 - 7.9e-36 122.8 0.0 9e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM00386.1 - 1.2e-13 51.6 0.0 1.7e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM00386.1 - 1.5e-05 24.3 0.0 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCM00386.1 - 0.0011 18.2 0.0 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCM00386.1 - 0.0073 15.4 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCM00386.1 - 0.026 14.4 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Clathrin PF00637.15 CCM00387.1 - 1.5e-206 676.2 27.8 3.6e-33 114.1 0.3 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 CCM00387.1 - 9.9e-34 113.3 1.5 0.0004 20.4 0.0 7.7 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 CCM00387.1 - 2.1e-30 104.4 0.1 1e-29 102.1 0.1 2.3 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.5 CCM00387.1 - 3.5e-10 38.6 0.1 1.2e-09 37.0 0.1 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 CCM00387.1 - 0.00027 19.8 5.2 2 7.1 0.1 4.4 4 0 0 4 4 4 2 Coatomer WD associated region TPR_2 PF07719.12 CCM00387.1 - 0.0011 18.7 6.9 12 6.1 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCM00387.1 - 0.0064 17.0 12.5 4.3 8.2 0.0 8.6 9 1 1 10 10 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCM00387.1 - 0.0077 16.1 1.2 1.1 9.3 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCM00387.1 - 0.021 14.3 6.6 14 5.5 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCM00387.1 - 0.095 12.5 8.8 19 5.3 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCM00387.1 - 0.18 11.7 11.9 2.7 8.0 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat DEAD PF00270.24 CCM00388.1 - 2.5e-37 127.9 0.0 6.1e-37 126.7 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCM00388.1 - 2.2e-24 84.7 0.8 8.6e-23 79.6 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCM00388.1 - 2.8e-18 65.5 0.0 6.5e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM00388.1 - 0.00048 20.0 0.5 0.004 16.9 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCM00388.1 - 0.048 13.8 0.0 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.9 CCM00388.1 - 0.052 12.1 1.1 5.3 5.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer AAA_19 PF13245.1 CCM00388.1 - 0.064 13.0 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain HGTP_anticodon2 PF12745.2 CCM00388.1 - 0.14 11.2 12.1 0.91 8.6 5.8 2.2 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs SDH_alpha PF03313.10 CCM00389.1 - 5.5e-83 278.2 3.3 8e-83 277.7 2.3 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 CCM00389.1 - 3.7e-11 43.3 0.0 1.1e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 Serine dehydratase beta chain UAA PF08449.6 CCM00390.1 - 5.7e-09 35.3 6.8 5.7e-09 35.3 4.7 1.8 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 CCM00390.1 - 9.4e-08 31.8 2.5 9.4e-08 31.8 1.7 3.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family CPSase_L_D2 PF02786.12 CCM00391.1 - 1.5e-79 266.2 0.1 2.9e-79 265.2 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CCM00391.1 - 1.2e-67 227.1 0.0 2.1e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CCM00391.1 - 3.6e-32 110.7 0.0 8.5e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 CCM00391.1 - 1.4e-27 96.8 0.0 3.4e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 CCM00391.1 - 4.7e-26 90.8 0.0 1.6e-25 89.1 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CCM00391.1 - 2.9e-19 69.5 0.1 5.3e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCM00391.1 - 4.4e-17 61.8 0.0 4.1e-16 58.6 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CCM00391.1 - 1.6e-12 46.8 3.8 6.6e-12 44.8 2.7 2.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CCM00391.1 - 1.6e-10 40.7 0.0 3.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CCM00391.1 - 2.6e-08 33.4 9.2 0.00016 21.3 0.9 3.0 3 0 0 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.17 CCM00391.1 - 1.2e-07 31.2 0.0 2.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CCM00391.1 - 3.9e-07 29.6 0.6 0.024 13.9 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 CCM00391.1 - 2.8e-06 27.2 0.0 6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 CCM00391.1 - 0.00013 22.2 0.8 0.15 12.4 0.0 3.1 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 CCM00391.1 - 0.00037 20.0 0.0 0.002 17.6 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 CCM00391.1 - 0.0022 17.5 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.6 CCM00391.1 - 0.047 12.8 0.5 0.17 11.0 0.2 1.9 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Peptidase_M23 PF01551.17 CCM00391.1 - 0.055 13.5 0.2 0.23 11.5 0.1 2.1 1 0 0 1 1 1 0 Peptidase family M23 GCV_H PF01597.14 CCM00391.1 - 0.057 13.1 2.3 0.2 11.3 0.3 2.7 2 1 1 3 3 3 0 Glycine cleavage H-protein HlyD_2 PF12700.2 CCM00391.1 - 0.082 12.0 0.6 0.37 9.9 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein eIF-3c_N PF05470.7 CCM00393.1 - 1.4e-184 614.5 23.4 1.4e-184 614.5 16.2 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CCM00393.1 - 1.9e-15 57.0 0.1 1e-14 54.7 0.0 2.4 2 0 0 2 2 2 1 PCI domain Auts2 PF15336.1 CCM00393.1 - 0.83 9.6 4.2 2.2 8.2 2.9 1.7 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Hexapep PF00132.19 CCM00394.1 - 1.9e-09 36.5 4.4 0.00017 20.9 0.5 3.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CCM00394.1 - 2.9e-05 24.2 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CCM00394.1 - 0.069 12.7 5.9 0.065 12.8 2.4 2.1 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.20 CCM00395.1 - 3.3e-66 223.1 0.0 5.1e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00395.1 - 2.3e-48 164.5 0.0 3.2e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM00395.1 - 9.8e-07 28.0 0.0 1.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCM00395.1 - 0.0012 18.6 0.0 0.26 10.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CCM00395.1 - 0.042 13.1 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CCM00395.1 - 0.13 11.3 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APS_kinase PF01583.15 CCM00396.1 - 3.9e-71 237.8 0.0 4.6e-71 237.5 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CCM00396.1 - 6e-08 32.6 0.0 8.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCM00396.1 - 9.9e-06 26.3 0.1 1.4e-05 25.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCM00396.1 - 1.2e-05 25.6 0.1 2e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCM00396.1 - 0.0011 18.4 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 CCM00396.1 - 0.0022 17.2 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 CCM00396.1 - 0.034 13.7 0.3 0.26 10.9 0.2 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 CCM00396.1 - 0.045 12.8 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Peptidase_C15 PF01470.12 CCM00397.1 - 0.00011 22.1 0.0 0.00061 19.6 0.0 2.2 3 1 0 3 3 3 1 Pyroglutamyl peptidase TAFH PF07531.9 CCM00397.1 - 0.084 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NHR1 homology to TAF Peptidase_C15 PF01470.12 CCM00398.1 - 7.4e-11 42.2 0.1 0.00016 21.5 0.0 2.7 1 1 0 2 2 2 2 Pyroglutamyl peptidase MgsA_C PF12002.3 CCM00399.1 - 4.2e-53 179.4 0.1 5.9e-53 179.0 0.1 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 CCM00399.1 - 4.4e-08 32.4 0.0 7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CCM00399.1 - 1e-07 32.2 0.1 3.1e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCM00399.1 - 0.00018 22.2 0.1 0.00055 20.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CCM00399.1 - 0.0004 20.5 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCM00399.1 - 0.00094 19.0 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCM00399.1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCM00399.1 - 0.002 17.8 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CCM00399.1 - 0.0021 18.0 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCM00399.1 - 0.004 17.1 0.1 0.0074 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 CCM00399.1 - 0.0051 15.5 0.0 0.015 13.9 0.0 1.6 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 CCM00399.1 - 0.0094 16.1 0.0 0.039 14.1 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 CCM00399.1 - 0.013 14.9 0.0 0.076 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA-like domain Mg_chelatase PF01078.16 CCM00399.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CCM00399.1 - 0.021 15.0 0.0 0.054 13.8 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 CCM00399.1 - 0.05 13.3 0.1 0.18 11.5 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 CCM00399.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain SKI PF01202.17 CCM00399.1 - 0.063 13.1 0.3 0.13 12.0 0.2 1.6 1 1 0 1 1 1 0 Shikimate kinase SET PF00856.23 CCM00400.1 - 6.3e-21 75.3 0.3 4.9e-20 72.4 0.2 2.6 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 CCM00400.1 - 6.9e-19 68.0 2.0 2.3e-18 66.3 1.4 1.9 1 0 0 1 1 1 1 Pre-SET motif zf-C2H2_2 PF12756.2 CCM00401.1 - 2e-28 98.4 0.0 3.5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CCM00401.1 - 0.078 13.3 0.6 17 6.0 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Rax2 PF12768.2 CCM00402.1 - 3.2e-82 275.8 21.2 1.9e-67 227.4 0.3 6.0 6 1 1 7 7 7 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 CCM00402.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Kelch_6 PF13964.1 CCM00402.1 - 0.093 12.9 8.4 2.2 8.6 0.0 5.3 5 1 2 7 7 7 0 Kelch motif Dioxygenase_C PF00775.16 CCM00403.1 - 1.2e-51 174.5 0.0 3.1e-51 173.2 0.0 1.6 2 0 0 2 2 2 1 Dioxygenase Dioxygenase_N PF04444.9 CCM00403.1 - 4.4e-14 52.1 0.0 1e-13 51.0 0.0 1.6 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 CCM00403.1 - 0.1 12.6 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain RPEL PF02755.10 CCM00405.1 - 6.2e-16 57.1 14.2 5.7e-09 35.0 2.9 3.0 3 0 0 3 3 3 2 RPEL repeat MCPVI PF02993.9 CCM00405.1 - 0.013 15.6 3.1 0.014 15.5 2.1 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DUF1279 PF06916.8 CCM00406.1 - 1.1e-15 57.6 0.0 1.8e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SAM_decarbox PF01536.11 CCM00407.1 - 2.5e-80 269.6 0.0 3.2e-78 262.7 0.0 2.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Zn_clus PF00172.13 CCM00408.1 - 1.2e-09 37.8 28.5 7.9e-05 22.4 9.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Dfp1_Him1_M PF08630.5 CCM00409.1 - 4.7e-20 71.6 0.0 9.4e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 CCM00409.1 - 2.4e-18 65.5 0.1 4.3e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 CCM00409.1 - 0.022 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.21 CCM00409.1 - 0.032 14.3 0.0 0.081 13.0 0.0 1.8 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF1045 PF06299.7 CCM00409.1 - 0.039 13.6 2.5 2 8.0 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) zf-met PF12874.2 CCM00409.1 - 0.27 11.4 1.1 0.69 10.2 0.8 1.7 1 1 0 1 1 1 0 Zinc-finger of C2H2 type OmpH PF03938.9 CCM00409.1 - 0.48 10.3 3.3 1.2 9.0 2.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc97_Spc98 PF04130.8 CCM00410.1 - 3.6e-39 134.5 0.0 1.8e-38 132.1 0.0 1.9 1 1 0 1 1 1 1 Spc97 / Spc98 family AAA_22 PF13401.1 CCM00411.1 - 9.3e-13 48.4 0.1 1.8e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM00411.1 - 4.1e-10 39.9 0.2 2.5e-09 37.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CCM00411.1 - 1.6e-08 34.8 0.1 4.2e-08 33.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CCM00411.1 - 1.2e-05 24.9 0.3 4.9e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM00411.1 - 1.6e-05 24.5 0.1 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CCM00411.1 - 3.9e-05 23.3 0.1 7.4e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 CCM00411.1 - 0.00013 21.8 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 CCM00411.1 - 0.0002 20.3 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_35 PF14516.1 CCM00411.1 - 0.00023 19.9 0.1 0.00034 19.3 0.1 1.2 1 0 0 1 1 1 1 AAA-like domain DUF2075 PF09848.4 CCM00411.1 - 0.001 18.1 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 CCM00411.1 - 0.0058 16.3 0.1 0.03 14.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 CCM00411.1 - 0.0092 15.0 2.4 0.31 9.9 0.2 2.7 2 1 1 3 3 3 1 KAP family P-loop domain cobW PF02492.14 CCM00411.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CCM00411.1 - 0.023 14.3 0.0 0.079 12.6 0.0 1.9 1 1 0 1 1 1 0 NTPase Helicase_RecD PF05127.9 CCM00411.1 - 0.027 14.1 0.1 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Helicase RNA_helicase PF00910.17 CCM00411.1 - 0.058 13.5 0.1 0.35 11.0 0.0 2.1 1 1 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.4 CCM00411.1 - 0.08 11.5 0.0 0.15 10.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TP6A_N PF04406.9 CCM00412.1 - 2.2e-20 72.0 0.0 5.6e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase BTB PF00651.26 CCM00413.1 - 0.005 16.8 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain COG2 PF06148.6 CCM00414.1 - 0.049 13.4 1.9 0.15 11.9 1.3 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Paramyx_P_V_C PF03210.8 CCM00414.1 - 0.079 12.8 0.1 0.079 12.8 0.1 3.2 3 1 1 4 4 4 0 Paramyxovirus P/V phosphoprotein C-terminal Ycf1 PF05758.7 CCM00414.1 - 0.16 9.6 0.0 0.2 9.3 0.0 1.1 1 0 0 1 1 1 0 Ycf1 DUF3435 PF11917.3 CCM00414.1 - 0.39 9.3 3.9 0.59 8.7 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) PhoU PF01895.14 CCM00414.1 - 0.73 10.3 4.7 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 PhoU domain Glyco_hydro_63 PF03200.11 CCM00415.1 - 1.8e-06 26.1 1.7 1.8e-06 26.1 1.2 3.9 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase RhoGAP PF00620.22 CCM00416.1 - 1.3e-31 109.2 0.0 2.3e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mito_carr PF00153.22 CCM00417.1 - 1e-45 153.3 2.0 1.1e-25 89.0 0.1 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein RhoGEF PF00621.15 CCM00418.1 - 5e-34 117.7 0.0 8.8e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 CCM00418.1 - 1e-33 115.9 0.0 2e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 CCM00418.1 - 1.4e-18 66.2 0.0 2.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.6 CCM00418.1 - 2.2e-11 43.6 0.0 4.3e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin Rap1-DNA-bind PF09197.5 CCM00419.1 - 0.00028 21.4 7.2 0.77 10.3 0.7 3.5 2 1 1 3 3 3 3 Rap1, DNA-binding Myb_DNA-bind_2 PF08914.6 CCM00419.1 - 0.0016 18.2 4.4 0.15 11.9 0.1 3.2 3 0 0 3 3 3 2 Rap1 Myb domain BRCT PF00533.21 CCM00419.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PhyH PF05721.8 CCM00420.1 - 5.3e-46 157.3 0.0 6.5e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HK PF02110.10 CCM00421.1 - 2.1e-72 243.2 1.7 3e-70 236.1 1.2 2.2 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CCM00421.1 - 8.2e-21 73.9 0.1 1.5e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 CCM00421.1 - 0.00042 19.5 0.0 0.001 18.3 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase SUR7 PF06687.7 CCM00424.1 - 7.5e-13 48.5 15.9 3.9e-12 46.1 10.9 1.9 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCM00424.1 - 0.00019 21.1 17.3 0.00046 19.9 11.0 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF456 PF04306.8 CCM00424.1 - 0.0024 17.8 9.9 0.0024 17.8 6.9 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF456) Amastin PF07344.6 CCM00424.1 - 0.11 12.0 8.6 0.16 11.6 5.8 1.3 1 1 0 1 1 1 0 Amastin surface glycoprotein Tetraspannin PF00335.15 CCM00424.1 - 0.28 10.4 17.7 0.23 10.6 5.5 2.4 1 1 1 2 2 2 0 Tetraspanin family DUF3188 PF11384.3 CCM00424.1 - 0.86 9.2 4.2 0.49 10.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF3169 PF11368.3 CCM00424.1 - 6.4 5.8 9.6 0.092 11.9 0.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) DUF3661 PF12400.3 CCM00425.1 - 5.1e-25 88.0 2.0 8.2e-25 87.3 1.4 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein PGAP1 PF07819.8 CCM00426.1 - 2.7e-49 167.8 0.0 3.7e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CCM00426.1 - 2.9e-08 33.5 0.0 1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM00426.1 - 5.5e-07 29.6 1.0 1.2e-06 28.5 0.7 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM00426.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.7 CCM00426.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.9 CCM00426.1 - 0.095 11.9 0.1 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) CorA PF01544.13 CCM00427.1 - 7.1e-47 159.8 0.2 9.8e-47 159.3 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 CCM00427.1 - 0.021 14.6 0.3 0.048 13.4 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.2 CCM00427.1 - 0.13 11.9 0.3 1.4 8.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) IPP-2 PF04979.9 CCM00428.1 - 2.1e-13 50.6 4.5 2e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) THF_DHG_CYH_C PF02882.14 CCM00429.1 - 1.2e-14 53.7 0.0 2.7e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCM00429.1 - 6.4e-14 51.9 0.0 9.9e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 CCM00429.1 - 0.044 13.8 0.0 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 CCM00429.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ORMDL PF04061.9 CCM00430.1 - 9.2e-52 174.2 3.3 1.1e-51 173.8 2.3 1.1 1 0 0 1 1 1 1 ORMDL family NUC130_3NT PF08158.7 CCM00431.1 - 0.015 15.5 1.7 0.67 10.2 0.1 3.6 3 0 0 3 3 3 0 NUC130/3NT domain DUF2404 PF10296.4 CCM00432.1 - 5.8e-05 23.1 0.0 0.0003 20.8 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) AAA PF00004.24 CCM00433.1 - 7.5e-55 184.7 0.0 5.8e-40 136.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCM00433.1 - 5.3e-11 42.7 0.2 0.0006 19.9 0.1 4.2 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.9 CCM00433.1 - 2e-09 37.3 0.0 0.001 18.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCM00433.1 - 6.4e-09 36.0 0.2 0.0063 16.5 0.1 3.1 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 CCM00433.1 - 8.5e-09 34.7 0.1 0.0014 17.6 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CCM00433.1 - 1.1e-08 35.1 0.0 1e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CCM00433.1 - 1.3e-08 35.6 0.0 0.0066 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CCM00433.1 - 2.2e-08 34.0 0.0 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCM00433.1 - 3e-08 33.3 0.3 0.0025 17.5 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain TIP49 PF06068.8 CCM00433.1 - 1.4e-07 30.6 0.0 0.0023 16.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 CCM00433.1 - 1.4e-07 30.8 0.3 0.0024 17.0 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 CCM00433.1 - 2.6e-07 30.1 0.2 1.4e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.1 CCM00433.1 - 4.6e-07 30.2 0.1 0.01 16.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 CCM00433.1 - 1.1e-06 28.7 0.0 0.052 13.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase CDC48_N PF02359.13 CCM00433.1 - 1.3e-06 28.2 0.0 3.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Zeta_toxin PF06414.7 CCM00433.1 - 3.9e-06 26.0 0.1 0.009 15.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CCM00433.1 - 5.1e-06 26.0 1.2 0.068 12.5 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 CCM00433.1 - 6.4e-06 26.0 0.0 0.077 12.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 CCM00433.1 - 7.2e-06 25.7 0.7 0.018 14.7 0.0 3.3 4 0 0 4 4 3 1 NACHT domain ABC_tran PF00005.22 CCM00433.1 - 7.3e-06 26.3 0.0 0.034 14.4 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_24 PF13479.1 CCM00433.1 - 1.4e-05 24.7 1.8 0.053 13.1 0.1 2.7 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CCM00433.1 - 1.5e-05 24.5 0.0 0.069 12.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 CCM00433.1 - 1.8e-05 24.2 3.1 0.45 9.8 0.1 4.1 2 2 1 4 4 4 2 AAA domain KaiC PF06745.8 CCM00433.1 - 3.5e-05 23.0 0.1 0.0048 16.0 0.1 2.4 2 0 0 2 2 2 1 KaiC AAA_3 PF07726.6 CCM00433.1 - 5e-05 22.9 0.0 0.089 12.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CCM00433.1 - 0.00011 21.8 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CCM00433.1 - 0.0002 20.9 0.0 0.74 9.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 CCM00433.1 - 0.00021 20.2 0.0 0.46 9.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 CCM00433.1 - 0.0003 20.7 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 CCM00433.1 - 0.0005 19.6 0.1 0.66 9.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CCM00433.1 - 0.00051 19.8 0.5 11 5.5 0.0 3.7 3 1 1 4 4 4 0 Archaeal ATPase KTI12 PF08433.5 CCM00433.1 - 0.00075 18.7 0.0 0.64 9.1 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 PhoH PF02562.11 CCM00433.1 - 0.0011 18.2 0.0 1.6 7.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.17 CCM00433.1 - 0.0012 17.7 0.1 0.61 8.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.9 CCM00433.1 - 0.0015 17.5 0.0 3.8 6.4 0.0 3.0 3 0 0 3 3 3 0 KAP family P-loop domain DUF2075 PF09848.4 CCM00433.1 - 0.0023 16.9 0.1 0.69 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 CCM00433.1 - 0.0027 17.3 0.1 0.041 13.5 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Torsin PF06309.6 CCM00433.1 - 0.0033 17.2 0.1 0.11 12.3 0.0 2.7 3 0 0 3 3 2 1 Torsin Sigma54_activ_2 PF14532.1 CCM00433.1 - 0.01 15.9 0.0 6.1 6.8 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain T2SE PF00437.15 CCM00433.1 - 0.013 14.4 0.0 4.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.10 CCM00433.1 - 0.023 14.5 0.0 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.24 CCM00433.1 - 0.029 13.8 0.3 23 4.4 0.0 3.9 2 2 1 4 4 4 0 DEAD/DEAH box helicase cobW PF02492.14 CCM00433.1 - 0.033 13.6 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 CCM00433.1 - 0.036 13.5 0.0 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain DAP3 PF10236.4 CCM00433.1 - 0.079 11.8 0.3 5.8 5.7 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 CCM00433.1 - 0.081 12.4 0.1 3.6 7.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 CCM00433.1 - 0.085 12.5 0.2 15 5.2 0.0 2.8 2 1 1 3 3 3 0 NTPase PCI PF01399.22 CCM00434.1 - 1.5e-10 41.2 0.0 1.8e-06 28.2 0.0 3.3 3 0 0 3 3 3 2 PCI domain DUF2009 PF09418.5 CCM00435.1 - 2.4e-205 682.6 0.0 3e-205 682.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 CCM00435.1 - 4.1e-06 26.5 9.0 1e-05 25.3 6.2 1.7 1 0 0 1 1 1 1 B-box zinc finger zf-HIT PF04438.11 CCM00435.1 - 0.26 10.9 1.5 0.53 9.9 1.0 1.5 1 0 0 1 1 1 0 HIT zinc finger DUF2797 PF10977.3 CCM00435.1 - 3.3 7.2 6.9 6 6.4 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) DUF2602 PF10782.4 CCM00435.1 - 4 7.3 8.1 1.1 9.1 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2602) Hep_59 PF07052.6 CCM00436.1 - 3.4e-26 91.6 0.8 3.4e-26 91.6 0.6 2.7 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 TFIIB PF00382.14 CCM00438.1 - 2.3e-34 117.0 0.0 1.6e-20 72.7 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CCM00438.1 - 9e-13 47.3 1.1 1.4e-12 46.6 0.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Guanylin PF02058.10 CCM00438.1 - 0.018 15.1 1.2 2.4 8.2 0.0 2.8 2 1 1 3 3 3 0 Guanylin precursor Cyclin_C PF02984.14 CCM00438.1 - 0.047 13.6 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain Cyclin_N PF00134.18 CCM00438.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain RRS1 PF04939.7 CCM00439.1 - 1.6e-58 196.8 2.9 1.6e-58 196.8 2.0 2.0 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) adh_short PF00106.20 CCM00440.1 - 5.1e-27 94.8 0.4 6.5e-27 94.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM00440.1 - 1.5e-09 37.7 0.1 2.2e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM00440.1 - 1.9e-09 37.6 0.0 2.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM00440.1 - 1.8e-05 24.8 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 CCM00440.1 - 0.004 16.3 0.0 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 CCM00440.1 - 0.019 14.4 0.0 0.064 12.6 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CCM00440.1 - 0.12 12.1 0.2 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Bac_surface_Ag PF01103.18 CCM00441.1 - 1.1e-41 143.3 0.1 1.4e-41 143.0 0.1 1.1 1 0 0 1 1 1 1 Surface antigen PriCT_1 PF08708.6 CCM00441.1 - 0.14 11.9 0.5 0.57 10.0 0.1 2.1 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) OPT PF03169.10 CCM00442.1 - 4.3e-143 478.0 56.9 4.9e-143 477.8 39.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.20 CCM00443.1 - 4.6e-22 78.4 0.0 3.6e-21 75.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00443.1 - 2.9e-16 59.3 0.0 1.4e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CCM00443.1 - 7.1e-05 22.2 0.7 0.00046 19.5 0.0 2.2 2 1 1 3 3 3 1 RIO1 family APH PF01636.18 CCM00443.1 - 0.00032 20.4 2.1 0.00062 19.5 0.0 2.3 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CCM00443.1 - 0.034 13.1 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_isomerase PF00160.16 CCM00444.1 - 1.9e-44 151.5 0.6 2.1e-44 151.4 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L18ae PF01775.12 CCM00446.1 - 7.1e-60 200.3 0.4 8.8e-60 200.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain COG7 PF10191.4 CCM00447.1 - 3.1e-75 253.6 0.1 8.3e-49 166.2 0.0 3.9 3 1 0 3 3 3 3 Golgi complex component 7 (COG7) DUF3008 PF11450.3 CCM00447.1 - 5.1 7.3 8.2 21 5.3 0.9 3.0 3 0 0 3 3 3 0 Protein of unknwon function (DUF3008) IBR PF01485.16 CCM00448.1 - 2.2e-07 30.6 30.5 2.2e-05 24.2 7.5 3.3 3 0 0 3 3 3 2 IBR domain DUF1190 PF06693.6 CCM00449.1 - 0.052 13.5 0.4 0.072 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) Toxin_62 PF15540.1 CCM00450.1 - 0.056 13.5 0.0 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative toxin 62 ketoacyl-synt PF00109.21 CCM00451.1 - 3.6e-46 157.7 2.6 6e-45 153.7 0.3 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CCM00451.1 - 5.4e-38 131.1 0.0 9.1e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 CCM00451.1 - 6.6e-28 96.9 0.1 1.3e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 CCM00451.1 - 7.7e-14 51.5 0.0 1.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 CCM00451.1 - 3.3e-05 23.0 0.1 6.6e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 CCM00451.1 - 0.0026 17.3 2.9 0.043 13.4 2.0 2.6 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III KR PF08659.5 CCM00452.1 - 3.8e-33 114.6 0.0 6e-32 110.7 0.0 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 CCM00452.1 - 9.4e-28 97.2 0.0 2.8e-27 95.6 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Thioesterase PF00975.15 CCM00452.1 - 5e-23 82.5 0.1 9.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Methyltransf_12 PF08242.7 CCM00452.1 - 3.5e-09 37.0 0.0 8.5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 CCM00452.1 - 3.9e-07 30.2 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 CCM00452.1 - 9.3e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 CCM00452.1 - 5.6e-05 23.1 0.0 0.0002 21.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 CCM00452.1 - 8.1e-05 23.0 0.0 0.00021 21.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM00452.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 CCM00452.1 - 0.0027 17.4 0.3 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family ThiF PF00899.16 CCM00452.1 - 0.0096 15.7 0.9 0.28 11.0 0.4 2.5 2 0 0 2 2 2 1 ThiF family Methyltransf_24 PF13578.1 CCM00452.1 - 0.024 15.4 0.1 0.77 10.6 0.0 3.3 3 1 0 3 3 3 0 Methyltransferase domain Cytotoxic PF09000.5 CCM00452.1 - 0.044 13.8 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Cytotoxic DUF2974 PF11187.3 CCM00452.1 - 0.047 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) 3Beta_HSD PF01073.14 CCM00452.1 - 0.081 11.6 0.0 0.29 9.7 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_32 PF13679.1 CCM00452.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain IgaA PF07095.6 CCM00452.1 - 0.34 8.5 0.0 0.56 7.8 0.0 1.2 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA GPP34 PF05719.6 CCM00454.1 - 1e-61 208.5 2.9 1.3e-61 208.2 2.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Chs3p PF12271.3 CCM00455.1 - 6.9e-48 163.1 8.0 1.4e-47 162.1 5.6 1.4 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit Zn_clus PF00172.13 CCM00456.1 - 2.6e-08 33.6 10.0 6.6e-08 32.3 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0203 PF05254.7 CCM00457.1 - 2.1e-14 53.1 0.4 1.9e-13 50.0 0.3 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX6B PF02297.12 CCM00457.1 - 0.16 12.0 2.8 3.6 7.6 2.1 2.0 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Metallophos_2 PF12850.2 CCM00458.1 - 4.8e-19 68.7 0.0 6.3e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CCM00458.1 - 5.2e-06 25.9 1.4 0.024 14.0 0.0 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Lipase_3 PF01764.20 CCM00459.1 - 1.4e-09 37.6 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Cation_ATPase_C PF00689.16 CCM00460.1 - 2.7e-09 36.8 0.3 2.9e-09 36.6 0.2 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus EBP PF05241.7 CCM00461.1 - 5.3e-10 38.6 2.5 9.4e-10 37.8 1.7 1.3 1 1 0 1 1 1 1 Emopamil binding protein HSP20 PF00011.16 CCM00462.1 - 2.1e-22 78.9 0.1 4.8e-22 77.7 0.0 1.6 1 1 1 2 2 2 1 Hsp20/alpha crystallin family VLPT PF07122.6 CCM00462.1 - 0.0033 17.0 0.2 0.011 15.3 0.1 1.9 1 1 0 1 1 1 1 Variable length PCR target protein (VLPT) F-box-like PF12937.2 CCM00463.1 - 0.0021 17.7 5.5 0.27 10.9 1.1 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 CCM00463.1 - 0.13 11.9 3.6 12 5.6 0.0 3.4 2 1 0 2 2 2 0 F-box domain Glyco_trans_2_3 PF13632.1 CCM00464.1 - 4.3e-52 176.6 0.8 4.3e-52 176.6 0.6 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCM00464.1 - 5.8e-10 39.3 0.1 2.6e-09 37.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CCM00464.1 - 0.0011 18.6 0.1 0.007 16.0 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCM00464.1 - 0.0051 16.1 0.0 0.014 14.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 CCM00465.1 - 2.7e-20 72.4 0.7 6.3e-20 71.2 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.17 CCM00466.1 - 2.5e-61 207.6 0.0 1.8e-60 204.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 WW PF00397.21 CCM00467.1 - 0.32 10.9 3.6 0.31 10.9 1.1 2.1 2 0 0 2 2 2 0 WW domain Senescence_reg PF04520.8 CCM00467.1 - 0.69 10.3 6.1 1.8 9.0 4.2 1.7 1 0 0 1 1 1 0 Senescence regulator tRNA-synt_1g PF09334.6 CCM00468.1 - 1.3e-94 317.1 0.0 2.3e-94 316.2 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCM00468.1 - 4.2e-15 54.7 0.4 3e-09 35.4 0.0 3.5 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CCM00468.1 - 1.9e-12 46.9 0.0 5e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain TPR_11 PF13414.1 CCM00469.1 - 7.4e-14 51.1 4.2 5.6e-12 45.1 0.2 3.2 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CCM00469.1 - 2.9e-07 29.8 3.9 0.088 12.7 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCM00469.1 - 8.4e-06 25.1 0.1 0.92 9.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.26 CCM00469.1 - 8.2e-05 22.3 0.0 0.00029 20.5 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain TPR_12 PF13424.1 CCM00469.1 - 0.00078 19.3 4.7 0.0023 17.8 0.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.26 CCM00469.1 - 0.0053 16.4 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.1 CCM00469.1 - 0.03 15.0 12.2 0.061 14.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCM00469.1 - 0.088 13.3 3.6 8.9 7.0 0.7 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 CCM00473.1 - 4e-149 497.2 0.0 7.4e-149 496.3 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 CCM00473.1 - 2.6e-53 176.1 1.5 5.4e-10 38.7 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCM00473.1 - 2.3e-05 24.0 0.2 4.6 7.0 0.0 4.6 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CCM00473.1 - 0.097 10.7 3.7 0.26 9.3 0.1 3.0 3 2 1 4 4 4 0 Nucleoporin Nup120/160 Chitin_synth_2 PF03142.10 CCM00474.1 - 6.8e-236 783.7 0.1 9e-236 783.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CCM00474.1 - 1.4e-111 373.6 0.0 3.3e-111 372.4 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 CCM00474.1 - 1.1e-17 64.5 0.0 3.8e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCM00474.1 - 4e-15 56.0 6.1 4e-15 56.0 4.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 CCM00474.1 - 6.2e-13 48.3 0.3 2.4e-12 46.4 0.2 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 CCM00474.1 - 2.2e-12 46.6 0.0 1.3e-08 34.4 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CCM00474.1 - 1.2e-08 34.8 0.0 1.1e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCM00474.1 - 5.7e-06 25.7 0.1 0.001 18.3 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF3253 PF11625.3 CCM00474.1 - 0.22 11.4 0.0 0.54 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) NUDIX PF00293.23 CCM00476.1 - 5.8e-12 45.4 0.0 8.7e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PH_BEACH PF14844.1 CCM00477.1 - 0.0034 17.1 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH stn_TNFRSF12A PF12191.3 CCM00477.1 - 0.031 14.3 0.2 0.063 13.3 0.2 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RabGAP-TBC PF00566.13 CCM00479.1 - 3.3e-40 137.8 0.1 4.7e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_N PF01602.15 CCM00480.1 - 1.9e-26 92.5 3.3 3.6e-26 91.6 2.3 1.4 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCM00480.1 - 0.002 18.3 0.1 0.91 9.8 0.1 3.4 2 2 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 CCM00480.1 - 0.014 15.2 1.5 0.24 11.2 0.4 3.0 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 UFD1 PF03152.9 CCM00481.1 - 2.5e-62 209.1 0.0 3.2e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 CCM00481.1 - 0.0089 15.6 0.0 0.048 13.3 0.0 2.1 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 NMT PF01233.14 CCM00482.1 - 1.3e-78 262.1 0.0 2.1e-78 261.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CCM00482.1 - 6.8e-65 218.0 0.0 1.2e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 CCM00482.1 - 5.8e-05 22.9 0.0 0.00042 20.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain OGG_N PF07934.7 CCM00483.1 - 4.9e-22 78.1 0.0 8.2e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CCM00483.1 - 4.6e-14 52.6 0.0 1.1e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCM00483.1 - 0.014 15.0 0.0 0.035 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif LRR_6 PF13516.1 CCM00484.1 - 0.25 11.5 2.7 27 5.2 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat p450 PF00067.17 CCM00485.1 - 6.2e-49 166.7 0.0 7.3e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 CCM00486.1 - 5.5e-21 74.4 0.6 1.4e-20 73.1 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM00486.1 - 1e-08 36.1 0.3 2.6e-08 34.7 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM00486.1 - 3e-07 30.1 1.5 2.8e-06 27.0 0.0 2.8 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 CCM00486.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NAD_binding_7 PF13241.1 CCM00486.1 - 0.14 12.3 0.7 4 7.7 0.5 2.3 1 1 0 1 1 1 0 Putative NAD(P)-binding YL1 PF05764.8 CCM00487.1 - 0.0021 17.7 0.3 0.0032 17.1 0.2 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF1664 PF07889.7 CCM00489.1 - 0.89 9.3 11.1 2.8 7.7 0.2 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 CCM00489.1 - 6.3 6.5 15.9 6.2 6.5 0.4 4.5 5 0 0 5 5 5 0 Spc24 subunit of Ndc80 DUF3505 PF12013.3 CCM00490.1 - 0.08 13.1 1.8 4.6 7.5 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) zf-C2H2 PF00096.21 CCM00490.1 - 0.24 11.8 17.1 1.4 9.4 0.0 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM00490.1 - 5.1 7.6 18.2 4.8 7.7 1.5 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Ribosomal_L37 PF08561.5 CCM00491.1 - 8.8e-18 63.6 0.1 1.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 MTBP_C PF14920.1 CCM00491.1 - 0.025 14.0 0.2 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 MDM2-binding UCH PF00443.24 CCM00492.1 - 3.3e-49 167.3 0.0 4.3e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM00492.1 - 9.5e-14 51.5 0.0 4.3e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PMT PF02366.13 CCM00493.1 - 5e-80 268.3 18.1 5e-80 268.3 12.5 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCM00493.1 - 9.3e-32 110.0 0.2 1.4e-31 109.5 0.1 1.2 1 0 0 1 1 1 1 MIR domain Fibrillarin PF01269.12 CCM00494.1 - 1.4e-108 361.1 0.0 1.7e-108 360.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin Methyltransf_31 PF13847.1 CCM00494.1 - 0.0024 17.4 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 CCM00494.1 - 0.0025 17.3 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CCM00494.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 CCM00494.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase MitMem_reg PF13012.1 CCM00495.1 - 1e-38 131.9 1.2 2e-38 131.0 0.9 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CCM00495.1 - 1.3e-26 92.5 0.0 1.3e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Med19 PF10278.4 CCM00495.1 - 1.8 8.2 13.0 3.2 7.3 9.0 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 COX4 PF02936.9 CCM00496.1 - 1.7e-35 121.8 0.0 1.9e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Patatin PF01734.17 CCM00496.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 Patatin-like phospholipase zf-CCHC PF00098.18 CCM00497.1 - 2.4e-52 172.4 56.9 1.4e-08 34.2 1.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CCM00497.1 - 5.9e-13 48.2 45.9 0.017 14.7 1.1 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 CCM00497.1 - 1.1e-09 37.8 38.5 0.032 13.9 0.4 7.0 3 2 4 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 CCM00497.1 - 0.00013 21.4 41.8 0.051 13.0 0.4 6.9 4 2 3 7 7 7 5 Zinc knuckle zf-CCHC_6 PF15288.1 CCM00497.1 - 0.0044 16.6 52.1 0.15 11.7 0.5 7.2 6 1 1 7 7 7 5 Zinc knuckle zf-CCHC_5 PF14787.1 CCM00497.1 - 0.038 13.4 1.0 0.038 13.4 0.7 4.9 5 1 1 6 6 6 0 GAG-polyprotein viral zinc-finger adh_short PF00106.20 CCM00498.1 - 3.7e-16 59.5 0.0 5.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CCM00498.1 - 0.00013 22.0 0.1 0.0007 19.6 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 CCM00498.1 - 0.00042 20.0 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM00498.1 - 0.0026 17.5 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 CCM00498.1 - 0.004 17.2 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 CCM00498.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CCM00498.1 - 0.011 14.9 0.0 0.95 8.5 0.0 2.2 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 CCM00498.1 - 0.014 14.3 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 CCM00498.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 CCM00498.1 - 0.022 13.7 0.1 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 CCM00498.1 - 0.026 14.3 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_2 PF03446.10 CCM00498.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 CCM00498.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 CCM00498.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCM00499.1 - 1e-45 155.0 0.0 1.5e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCM00499.1 - 3.3e-19 68.6 0.0 4.3e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 CCM00499.1 - 0.0088 15.6 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.14 CCM00499.1 - 0.045 12.8 2.2 2.5 7.1 0.7 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GFO_IDH_MocA PF01408.17 CCM00499.1 - 0.048 14.1 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.1 CCM00499.1 - 0.071 13.3 0.2 0.49 10.6 0.0 2.4 3 0 0 3 3 3 0 Putative NAD(P)-binding tRNA-synt_1c PF00749.16 CCM00500.1 - 9.8e-103 343.0 0.0 1.3e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CCM00500.1 - 4.4e-37 127.4 0.2 7.9e-37 126.5 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.1 CCM00500.1 - 6e-07 29.2 0.1 1.6e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCM00500.1 - 1.6e-05 25.2 0.0 5.8e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCM00500.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 CCM00500.1 - 0.011 14.9 0.6 0.023 13.8 0.2 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Methyltransf_10 PF05971.7 CCM00501.1 - 2.5e-49 168.0 0.1 3.1e-31 108.6 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF890) MTS PF05175.9 CCM00501.1 - 0.0011 18.3 0.0 0.031 13.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CCM00501.1 - 0.0064 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCM00501.1 - 0.02 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Metallophos_2 PF12850.2 CCM00502.1 - 0.00023 21.0 0.0 0.00089 19.1 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CCM00502.1 - 0.00038 19.8 4.1 0.0023 17.3 2.9 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HMGL-like PF00682.14 CCM00503.1 - 7.7e-59 199.2 0.0 1.5e-58 198.3 0.0 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 CCM00503.1 - 1.4e-45 154.3 0.2 4.2e-23 81.6 0.0 2.5 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain AvrPtoB-E3_ubiq PF09046.5 CCM00503.1 - 0.13 12.3 0.0 0.55 10.2 0.0 2.0 2 0 0 2 2 2 0 AvrPtoB E3 ubiquitin ligase DUF3129 PF11327.3 CCM00503.1 - 0.13 12.0 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3129) DUF382 PF04037.8 CCM00504.1 - 8.9e-61 203.3 0.2 2.8e-60 201.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 CCM00504.1 - 6.7e-19 67.0 6.6 1.3e-18 66.0 4.6 1.5 1 0 0 1 1 1 1 PSP DEAD PF00270.24 CCM00505.1 - 9.9e-43 145.5 2.7 2.8e-42 144.1 0.6 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM00505.1 - 7.1e-27 93.0 0.2 2.7e-26 91.2 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM00505.1 - 0.00096 19.0 0.1 0.0019 18.0 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCM00505.1 - 0.0011 18.6 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCM00505.1 - 0.0098 15.4 0.4 0.027 14.0 0.2 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCM00505.1 - 0.016 15.3 0.9 0.061 13.4 0.2 2.4 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 CCM00505.1 - 0.041 13.1 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.20 CCM00505.1 - 0.09 11.8 0.1 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 CCM00505.1 - 0.099 12.3 0.1 0.41 10.3 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain DSPc PF00782.15 CCM00506.1 - 1.9e-25 88.9 0.0 2.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCM00506.1 - 0.0057 16.0 0.0 0.0073 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 CCM00506.1 - 0.025 13.4 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Myotub-related PF06602.9 CCM00506.1 - 0.09 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPn PF14671.1 CCM00506.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Ras PF00071.17 CCM00507.1 - 3.5e-48 163.0 0.0 4.4e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM00507.1 - 1.6e-11 44.7 0.0 2.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM00507.1 - 1.7e-10 40.3 0.0 2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM00507.1 - 6.1e-05 22.5 0.0 0.00011 21.7 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCM00507.1 - 0.069 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_Eps PF04627.8 CCM00508.1 - 6.4e-22 76.8 2.7 8.1e-22 76.5 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain AcylCoA_dehyd_C PF12186.3 CCM00509.1 - 0.37 10.6 3.8 0.36 10.6 0.3 2.4 1 1 2 3 3 3 0 Acyl-CoA dehydrogenase C terminal CHAT PF12770.2 CCM00511.1 - 4.5e-32 111.3 0.0 1e-31 110.1 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 CCM00511.1 - 3.3e-17 61.8 30.0 0.0039 16.7 0.0 12.1 6 4 7 13 13 13 7 TPR repeat TPR_12 PF13424.1 CCM00511.1 - 2.6e-14 52.9 39.3 0.0096 15.8 0.2 13.8 11 3 5 16 16 16 7 Tetratricopeptide repeat TPR_17 PF13431.1 CCM00511.1 - 2.5e-05 24.0 3.2 8.1 6.9 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCM00511.1 - 0.54 10.2 0.0 0.54 10.2 0.0 10.4 9 2 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCM00511.1 - 2.1 8.0 19.5 2.6 7.7 0.1 8.8 9 0 0 9 9 9 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 CCM00512.1 - 2.4e-18 66.7 0.0 4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.2 CCM00512.1 - 0.027 13.5 0.0 0.095 11.8 0.0 1.8 2 0 0 2 2 2 0 CHAT domain Peptidase_C14 PF00656.17 CCM00513.1 - 7.5e-20 71.6 0.0 1.2e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DUF4158 PF13700.1 CCM00513.1 - 0.13 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Peptidase_C14 PF00656.17 CCM00515.1 - 1.9e-20 73.6 0.0 3.9e-20 72.6 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 CCM00516.1 - 1.7e-18 67.1 0.0 2.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Pkinase PF00069.20 CCM00517.1 - 7.2e-53 179.3 0.0 1e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00517.1 - 5.1e-47 160.1 0.0 6.9e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 CCM00517.1 - 0.0014 18.0 0.1 0.0077 15.7 0.2 2.3 2 0 0 2 2 2 1 SAP domain APH PF01636.18 CCM00517.1 - 0.0069 16.1 0.0 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCM00517.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AMP-binding PF00501.23 CCM00518.1 - 3.1e-48 164.2 1.1 1.8e-29 102.3 0.0 2.9 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CCM00518.1 - 6e-16 59.1 0.1 1.9e-15 57.5 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Npa1 PF11707.3 CCM00519.1 - 2.8e-71 240.2 0.1 8.3e-71 238.6 0.0 1.8 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Rsa3 PF14615.1 CCM00520.1 - 8.9e-12 44.1 0.0 1.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Cwf_Cwc_15 PF04889.7 CCM00520.1 - 0.09 12.4 7.1 0.16 11.6 4.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DDE_Tnp_1 PF01609.16 CCM00520.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain Pox_Ag35 PF03286.9 CCM00520.1 - 0.57 9.6 4.9 0.61 9.5 2.3 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC45 PF02724.9 CCM00520.1 - 0.76 7.7 4.0 0.83 7.6 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NST1 PF13945.1 CCM00520.1 - 1 9.3 9.9 1.4 9.0 2.9 2.1 1 1 1 2 2 2 0 Salt tolerance down-regulator DUF605 PF04652.11 CCM00520.1 - 1.8 7.8 18.7 2 7.6 13.0 1.1 1 0 0 1 1 1 0 Vta1 like AIRC PF00731.15 CCM00521.1 - 2.9e-62 208.3 2.1 5.7e-62 207.4 1.5 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 CCM00521.1 - 6.5e-58 194.8 0.0 9.2e-58 194.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CCM00521.1 - 7.6e-12 45.3 0.1 1.4e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCM00521.1 - 5.3e-06 25.4 0.0 0.0017 17.1 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 CCM00521.1 - 0.00082 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 CCM00521.1 - 0.0025 17.2 0.0 0.012 14.9 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CCM00521.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain CoA_binding_2 PF13380.1 CCM00521.1 - 0.13 12.4 1.3 18 5.5 0.0 3.2 2 1 1 3 3 3 0 CoA binding domain F-box PF00646.28 CCM00522.1 - 3.2e-05 23.4 0.0 0.00011 21.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 CCM00522.1 - 0.0003 20.3 0.1 2.8 7.6 0.0 4.9 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) Aminotran_1_2 PF00155.16 CCM00523.1 - 1.3e-22 80.3 0.0 1.6e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCM00523.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_MocR PF12897.2 CCM00523.1 - 0.14 10.6 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase F-box PF00646.28 CCM00525.1 - 0.00065 19.2 0.2 0.0022 17.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain Clp1 PF06807.9 CCM00528.1 - 1.2e-19 70.8 0.0 3.9e-17 62.6 0.0 2.2 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CCM00528.1 - 2.6e-07 30.4 0.0 5.7e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CCM00528.1 - 0.15 12.8 0.0 0.35 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.9 CCM00529.1 - 1.4e-21 77.2 0.0 2.3e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM00529.1 - 8.6e-12 45.3 0.2 8.4e-07 29.3 0.0 3.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 CCM00529.1 - 3.5e-11 41.5 1.3 3e-05 23.0 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CCM00529.1 - 1e-09 38.4 0.0 0.00039 20.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCM00529.1 - 8.2e-09 34.6 0.9 0.00022 20.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CCM00529.1 - 7.2e-07 28.2 2.0 0.00061 19.0 0.2 2.5 2 0 0 2 2 2 2 EF hand Pyr_redox_3 PF13738.1 CCM00529.1 - 3.4e-06 27.2 0.0 0.022 14.8 0.0 3.0 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 CCM00529.1 - 3.9e-06 26.3 1.4 0.084 12.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair NAD_binding_7 PF13241.1 CCM00529.1 - 0.0031 17.7 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Bd3614-deam PF14439.1 CCM00529.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase EF-hand_4 PF12763.2 CCM00529.1 - 0.18 11.5 2.0 11 5.8 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand LRR_4 PF12799.2 CCM00530.1 - 3e-05 23.5 0.9 0.56 9.8 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM00530.1 - 0.018 14.7 2.6 3.5 7.4 0.1 3.7 2 1 1 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 CCM00530.1 - 0.04 14.0 2.8 38 5.1 0.0 5.1 6 0 0 6 6 6 0 Leucine rich repeat Asp PF00026.18 CCM00531.1 - 5.1e-70 236.2 7.8 6.5e-70 235.8 5.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM00531.1 - 8.9e-06 25.7 1.6 2.5e-05 24.2 0.7 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Pkinase_Tyr PF07714.12 CCM00532.1 - 1.4e-49 168.5 0.0 2.2e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM00532.1 - 1.7e-41 142.1 0.0 2.9e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CCM00532.1 - 0.003 16.5 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCM00532.1 - 0.004 16.2 0.0 0.0087 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM00532.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CCM00532.1 - 0.19 11.4 0.2 0.6 9.7 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family S-AdoMet_synt_C PF02773.11 CCM00533.1 - 6e-75 249.5 0.5 1.2e-74 248.6 0.4 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CCM00533.1 - 1.6e-49 166.8 0.0 2.7e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CCM00533.1 - 2.4e-43 146.4 0.1 2.4e-43 146.4 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-antigen PF05756.6 CCM00533.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 S-antigen protein Myotub-related PF06602.9 CCM00534.1 - 2.3e-128 427.8 0.1 4e-128 427.1 0.0 1.3 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 CCM00534.1 - 0.023 14.0 0.2 0.066 12.5 0.0 1.8 2 1 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CCM00534.1 - 0.068 13.4 0.1 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.15 CCM00534.1 - 0.13 11.8 0.1 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Glyco_hydro_43 PF04616.9 CCM00535.1 - 8.8e-34 116.8 2.9 1.7e-33 115.9 1.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.9 CCM00536.1 - 1.9e-39 135.4 0.7 2.9e-39 134.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3808 PF10300.4 CCM00537.1 - 2.7e-79 266.9 0.0 4.1e-79 266.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 CCM00537.1 - 3.3e-05 23.4 7.0 0.013 15.1 0.6 4.5 4 1 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 CCM00537.1 - 5e-05 22.9 13.3 0.012 15.4 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM00537.1 - 0.0012 18.7 8.0 0.52 10.2 0.0 4.9 4 2 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCM00537.1 - 0.0019 17.8 1.5 11 6.0 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCM00537.1 - 0.023 14.2 0.8 0.56 9.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCM00537.1 - 0.23 11.9 4.3 31 5.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCM00537.1 - 1.2 9.9 6.6 8 7.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_38 PF01074.17 CCM00538.1 - 4.1e-82 275.5 0.0 6.5e-82 274.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CCM00538.1 - 2.1e-59 201.5 0.0 3.5e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CCM00538.1 - 2.7e-26 91.5 0.0 5.9e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain GFO_IDH_MocA PF01408.17 CCM00539.1 - 2.5e-15 57.0 0.0 3.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Aerolysin PF01117.15 CCM00540.1 - 0.0064 15.4 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Aerolysin toxin ETX_MTX2 PF03318.8 CCM00540.1 - 0.13 11.7 3.2 0.25 10.8 2.2 1.5 1 1 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Cupin_8 PF13621.1 CCM00541.1 - 7.4e-54 182.8 0.0 1.2e-53 182.1 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CCM00541.1 - 9.1e-05 21.8 0.0 0.24 10.5 0.0 2.8 3 0 0 3 3 3 2 Cupin superfamily protein DUF4611 PF15387.1 CCM00541.1 - 0.34 11.0 5.1 0.21 11.7 2.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Nop14 PF04147.7 CCM00541.1 - 2.3 6.0 8.7 3 5.6 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family RNase_T PF00929.19 CCM00542.1 - 6.2e-18 65.6 0.0 9.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease IBR PF01485.16 CCM00543.1 - 7.4e-09 35.3 35.7 2e-06 27.5 5.3 3.4 3 0 0 3 3 3 3 IBR domain HATPase_c_2 PF13581.1 CCM00543.1 - 0.035 13.9 0.0 3.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain adh_short PF00106.20 CCM00544.1 - 9.7e-16 58.1 0.0 2.2e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM00544.1 - 2.4e-09 37.3 0.1 3.2e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM00544.1 - 0.00016 21.3 0.0 0.00064 19.4 0.0 1.9 2 1 1 3 3 3 1 KR domain NAD_binding_10 PF13460.1 CCM00544.1 - 0.00054 20.0 0.1 0.0016 18.4 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCM00544.1 - 0.00055 19.2 0.0 0.00086 18.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Alpha-amylase PF00128.19 CCM00545.1 - 2.3e-64 217.7 0.8 2.9e-64 217.4 0.5 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 CCM00545.1 - 2e-13 50.2 0.1 4.2e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.19 CCM00546.1 - 1.9e-64 218.0 0.9 2.4e-64 217.7 0.6 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 CCM00546.1 - 6.7e-15 54.9 0.1 1.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Beta-lactamase PF00144.19 CCM00547.1 - 3.4e-41 141.3 0.1 4.6e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 CCM00547.1 - 0.005 16.6 0.0 0.041 13.7 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3471) adh_short PF00106.20 CCM00548.1 - 9.8e-13 48.3 2.4 2.2e-12 47.2 1.7 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM00548.1 - 2.4e-08 34.0 0.1 3.2e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM00548.1 - 0.0096 15.5 1.4 0.018 14.6 1.0 1.8 1 1 0 1 1 1 1 KR domain UDG PF03167.14 CCM00548.1 - 0.032 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily adh_short PF00106.20 CCM00549.1 - 2.2e-15 56.9 1.9 3.3e-15 56.3 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM00549.1 - 2.4e-06 27.4 0.1 2.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 CCM00549.1 - 0.0017 18.0 0.1 0.003 17.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 CCM00549.1 - 0.02 14.4 0.1 0.06 12.9 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus PIP5K PF01504.13 CCM00550.1 - 4e-50 170.2 0.0 1e-49 168.9 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pro_isomerase PF00160.16 CCM00551.1 - 1.2e-35 123.0 0.0 1e-34 119.9 0.0 1.9 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2470 PF10615.4 CCM00552.1 - 2.3e-16 59.7 0.0 3.5e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 CCM00552.1 - 7e-10 38.7 0.5 1.4e-09 37.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DIM1 PF02966.11 CCM00553.1 - 6.6e-69 229.5 0.1 7.4e-69 229.4 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CCM00553.1 - 5.9e-05 22.7 0.1 7.6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCM00553.1 - 0.009 16.1 0.2 0.013 15.6 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.10 CCM00553.1 - 0.019 14.6 0.3 0.035 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 CCM00553.1 - 0.025 14.5 0.1 0.052 13.5 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin-like GIDA PF01134.17 CCM00554.1 - 7e-154 512.4 0.0 8.3e-154 512.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CCM00554.1 - 1.3e-09 38.0 0.0 3.5e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 CCM00554.1 - 4.9e-07 29.1 0.1 6.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCM00554.1 - 1.3e-05 25.2 0.4 2.7e-05 24.1 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCM00554.1 - 0.0007 18.5 3.0 0.0017 17.2 2.1 1.7 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CCM00554.1 - 0.0022 16.5 1.4 0.066 11.6 0.4 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 CCM00554.1 - 0.013 15.8 0.4 0.031 14.6 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM00554.1 - 0.13 11.0 3.8 0.14 11.0 0.9 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase zf-CSL PF05207.8 CCM00555.1 - 3e-25 87.4 0.8 5.6e-25 86.5 0.6 1.5 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 CCM00555.1 - 0.013 15.4 0.7 0.023 14.6 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Terminase_GpA PF05876.7 CCM00555.1 - 0.043 12.1 0.7 0.057 11.7 0.5 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_5 PF13719.1 CCM00555.1 - 0.058 12.9 0.5 0.092 12.3 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain GAGA PF09237.6 CCM00555.1 - 0.094 12.3 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 GAGA factor zinc_ribbon_4 PF13717.1 CCM00555.1 - 0.16 11.6 0.7 0.27 10.9 0.5 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Prenyltrans PF00432.16 CCM00556.1 - 1e-54 181.7 1.6 5.5e-12 45.0 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCM00556.1 - 6e-31 107.1 0.0 2.9e-14 53.4 0.0 3.1 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCM00556.1 - 4.9e-09 36.1 0.0 1.3e-06 28.3 0.0 3.2 2 1 1 3 3 3 1 Prenyltransferase-like Rad60-SLD PF11976.3 CCM00557.1 - 1.6e-25 88.5 0.4 1.9e-25 88.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CCM00557.1 - 5e-11 41.8 0.1 5.9e-11 41.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Cadherin-like PF12733.2 CCM00557.1 - 0.018 15.3 1.4 0.6 10.4 0.1 2.5 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain UreE_N PF02814.10 CCM00557.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain MFS_1 PF07690.11 CCM00560.1 - 1.9e-24 86.0 60.9 9.3e-18 64.0 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCM00560.1 - 1.1e-07 30.6 9.6 1.1e-07 30.6 6.6 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 CCM00560.1 - 0.00026 20.7 0.8 0.00026 20.7 0.5 2.6 2 1 0 2 2 2 1 MFS_1 like family ECH_C PF13766.1 CCM00561.1 - 4.1e-26 91.4 0.0 9.4e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CCM00561.1 - 6.8e-20 71.2 0.0 1.2e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2497 PF10691.4 CCM00561.1 - 0.096 12.6 0.3 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) HNH_2 PF13391.1 CCM00564.1 - 0.075 12.8 0.1 2.3 8.0 0.0 2.4 1 1 1 2 2 2 0 HNH endonuclease GMC_oxred_N PF00732.14 CCM00565.1 - 1.2e-51 175.6 0.0 2.5e-51 174.5 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM00565.1 - 1e-16 61.5 0.0 2.1e-13 50.7 0.0 2.3 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM00565.1 - 0.00027 19.9 0.7 0.0022 16.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCM00565.1 - 0.00027 20.8 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCM00565.1 - 0.00075 18.4 0.3 0.0043 15.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 CCM00565.1 - 0.0015 17.4 0.1 0.0023 16.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CCM00565.1 - 0.041 12.9 0.1 0.073 12.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 CCM00565.1 - 0.048 12.1 0.0 0.22 9.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 CCM00565.1 - 0.1 12.6 0.0 5.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CCM00565.1 - 0.16 11.9 0.1 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_31 PF01055.21 CCM00566.1 - 5.9e-135 450.5 2.5 7e-135 450.2 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.21 CCM00567.1 - 2.1e-12 46.5 0.0 2.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCM00567.1 - 6.8e-06 25.8 0.1 1.8e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like CFEM PF05730.6 CCM00568.1 - 3.5e-05 23.5 14.6 7.9e-05 22.4 10.1 1.6 1 0 0 1 1 1 1 CFEM domain Acetyltransf_4 PF13420.1 CCM00569.1 - 1.9e-16 60.3 0.0 3.8e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCM00569.1 - 1.1e-11 45.1 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM00569.1 - 1.6e-07 31.2 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCM00569.1 - 6.6e-06 26.2 0.1 1.4e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCM00569.1 - 0.00015 21.8 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCM00569.1 - 0.0045 16.8 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 CCM00569.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF4034 PF13226.1 CCM00570.1 - 0.05 12.6 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) DHH PF01368.15 CCM00571.1 - 1.6e-06 27.8 0.0 3.1e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 DHH family CDO_I PF05995.7 CCM00576.1 - 1.2e-06 27.8 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 CCM00576.1 - 3.9e-05 23.1 0.8 8.6e-05 21.9 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) AMP-binding PF00501.23 CCM00577.1 - 2.8e-23 81.9 0.0 9.2e-21 73.6 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.8 CCM00577.1 - 0.03 12.8 0.1 0.046 12.2 0.1 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter TPR_11 PF13414.1 CCM00578.1 - 0.0014 18.2 0.3 0.0041 16.7 0.2 1.8 1 0 0 1 1 1 1 TPR repeat zf-CCCH PF00642.19 CCM00578.1 - 2.8 7.7 16.8 1.1 9.0 3.4 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ABC_tran PF00005.22 CCM00579.1 - 2.5e-44 150.8 2.0 1.3e-26 93.5 0.1 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 CCM00579.1 - 1.3e-32 113.3 27.3 5.4e-18 65.3 1.7 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 CCM00579.1 - 1.5e-11 43.9 5.2 0.007 15.6 2.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCM00579.1 - 2.7e-10 40.7 0.2 0.18 11.7 0.0 4.3 2 2 1 3 3 3 3 AAA domain AAA_25 PF13481.1 CCM00579.1 - 1.4e-06 27.8 0.1 0.038 13.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 CCM00579.1 - 1.4e-06 27.7 0.3 0.067 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CCM00579.1 - 2e-06 28.2 0.2 0.0014 19.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCM00579.1 - 7.3e-06 26.0 2.9 0.007 16.3 1.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CCM00579.1 - 1.6e-05 24.4 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 CCM00579.1 - 0.00025 20.0 0.2 0.066 12.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 CCM00579.1 - 0.00067 19.5 0.3 0.065 13.0 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 CCM00579.1 - 0.0008 19.1 0.2 0.64 9.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CCM00579.1 - 0.00087 19.2 0.1 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 CCM00579.1 - 0.00099 19.9 0.0 2.4 9.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCM00579.1 - 0.0016 18.9 0.0 3.6 8.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CCM00579.1 - 0.0023 18.0 2.1 2 8.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 CCM00579.1 - 0.0073 16.1 0.0 0.58 9.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 CCM00579.1 - 0.0079 15.3 0.0 0.69 8.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 CCM00579.1 - 0.0083 15.5 3.4 2.7 7.3 0.1 3.0 2 1 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 CCM00579.1 - 0.0091 15.1 0.1 3.6 6.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCM00579.1 - 0.0099 16.1 0.0 7.9 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 CCM00579.1 - 0.01 15.3 0.1 3.5 7.0 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.1 CCM00579.1 - 0.013 15.1 0.2 5.6 6.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 CCM00579.1 - 0.027 13.1 0.0 0.22 10.1 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 CCM00579.1 - 0.029 14.0 0.0 4.7 6.8 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase ATP-synt_ab PF00006.20 CCM00579.1 - 0.035 13.5 0.1 9.8 5.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TrwB_AAD_bind PF10412.4 CCM00579.1 - 0.044 12.4 0.7 5 5.6 0.1 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 CCM00579.1 - 0.044 13.1 0.8 11 5.4 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.18 CCM00579.1 - 0.046 13.5 0.2 4.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.9 CCM00579.1 - 0.047 13.4 0.2 12 5.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 CCM00579.1 - 0.071 12.3 0.9 4.1 6.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 CCM00579.1 - 0.1 12.4 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CCM00579.1 - 3.4 7.2 5.3 11 5.6 0.1 3.2 3 0 0 3 3 3 0 NACHT domain Isy1 PF06246.7 CCM00580.1 - 8.1e-81 271.1 3.1 1.1e-80 270.7 2.2 1.2 1 0 0 1 1 1 1 Isy1-like splicing family P22_Tail-4 PF11650.3 CCM00580.1 - 0.022 14.2 0.5 0.071 12.6 0.0 1.9 2 0 0 2 2 2 0 P22 tail accessory factor DNA_pack_C PF02499.10 CCM00581.1 - 0.054 12.2 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus LysM PF01476.15 CCM00582.1 - 1.3e-54 181.8 10.7 1e-08 34.9 0.1 7.5 7 0 0 7 7 7 7 LysM domain Glyco_hydro_18 PF00704.23 CCM00583.1 - 1.1e-77 261.7 0.2 1.7e-77 261.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 CCM00583.1 - 3.2e-13 49.4 56.3 3.7e-11 42.8 9.8 3.7 3 0 0 3 3 3 2 Chitin recognition protein WD40 PF00400.27 CCM00584.1 - 3.9e-66 216.7 28.5 5.2e-12 45.1 0.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Gmad1 PF10647.4 CCM00584.1 - 5.1e-05 22.7 0.0 0.095 12.0 0.0 2.5 1 1 2 3 3 3 3 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 CCM00584.1 - 0.00011 22.2 1.6 1.3 9.3 0.0 4.8 3 2 2 5 5 5 1 PQQ-like domain Nup160 PF11715.3 CCM00584.1 - 0.00017 19.8 2.9 2.6 6.0 0.0 4.8 4 3 2 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCM00584.1 - 0.069 12.6 3.9 4.3 6.7 1.9 2.8 1 1 1 2 2 2 0 PQQ-like domain NB-ARC PF00931.17 CCM00584.1 - 0.16 10.8 0.0 0.37 9.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Nucleoporin_N PF08801.6 CCM00584.1 - 0.58 8.8 12.5 3.1 6.4 2.7 4.2 1 1 1 2 2 2 0 Nup133 N terminal like WD40 PF00400.27 CCM00585.1 - 3.4e-159 511.7 79.4 4.6e-12 45.3 0.2 15.3 15 0 0 15 15 15 14 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCM00585.1 - 5.8e-08 31.9 51.5 0.49 9.0 0.4 11.7 2 2 4 8 8 8 6 Nup133 N terminal like Nup160 PF11715.3 CCM00585.1 - 9.8e-08 30.5 33.2 0.39 8.7 0.0 11.7 1 1 7 10 10 10 5 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CCM00585.1 - 6.7e-07 29.3 17.9 17 5.8 0.0 11.1 4 3 9 13 13 13 0 PQQ-like domain PQQ_2 PF13360.1 CCM00585.1 - 4.3e-06 26.3 19.9 0.37 10.2 0.1 6.4 1 1 2 4 4 4 2 PQQ-like domain NACHT PF05729.7 CCM00585.1 - 1.1e-05 25.1 0.4 6.2e-05 22.7 0.3 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CCM00585.1 - 0.0005 20.1 0.2 0.0015 18.5 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCM00585.1 - 0.00091 19.3 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF4353 PF14262.1 CCM00585.1 - 0.0018 17.4 3.2 7.3 5.7 0.0 5.8 5 3 2 7 7 7 1 Domain of unknown function (DUF4353) Cytochrom_D1 PF02239.11 CCM00585.1 - 0.0052 15.1 18.8 0.11 10.7 0.3 5.7 2 2 4 7 7 7 4 Cytochrome D1 heme domain DUF727 PF05303.7 CCM00585.1 - 0.0084 15.8 6.8 27 4.5 0.0 7.9 9 1 1 10 10 10 0 Protein of unknown function (DUF727) NB-ARC PF00931.17 CCM00585.1 - 0.035 12.9 0.0 0.066 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Peptidase_S9_N PF02897.10 CCM00585.1 - 0.068 11.7 2.6 16 3.8 0.1 5.1 3 2 1 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain zf-C3HC4 PF00097.20 CCM00586.1 - 1.8e-06 27.4 8.3 5.5e-06 25.9 5.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCM00586.1 - 3.8e-05 23.4 13.9 7.1e-05 22.5 9.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCM00586.1 - 0.0053 16.7 13.6 0.011 15.7 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.4 CCM00586.1 - 0.0066 15.4 4.8 0.012 14.5 3.3 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 CCM00586.1 - 0.0086 16.0 13.5 0.015 15.2 9.3 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) zf-C3HC4_4 PF15227.1 CCM00586.1 - 0.0098 15.7 11.3 0.029 14.2 7.3 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING DUF3552 PF12072.3 CCM00586.1 - 0.013 14.7 22.1 0.068 12.3 15.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) IncA PF04156.9 CCM00586.1 - 0.022 14.3 13.1 0.031 13.8 9.0 1.2 1 0 0 1 1 1 0 IncA protein IFT57 PF10498.4 CCM00586.1 - 0.056 12.1 9.2 0.082 11.6 6.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 zf-C3HC4_3 PF13920.1 CCM00586.1 - 0.056 13.1 9.9 0.19 11.4 6.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2130 PF09903.4 CCM00586.1 - 0.077 11.7 9.2 0.11 11.2 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) RmuC PF02646.11 CCM00586.1 - 0.098 11.4 10.4 0.14 10.9 7.2 1.2 1 0 0 1 1 1 0 RmuC family ATG16 PF08614.6 CCM00586.1 - 0.1 12.4 14.6 0.19 11.5 10.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-RING_5 PF14634.1 CCM00586.1 - 0.1 12.3 12.2 0.68 9.7 8.0 2.3 1 1 0 1 1 1 0 zinc-RING finger domain Mnd1 PF03962.10 CCM00586.1 - 0.15 11.6 10.9 0.24 11.0 7.6 1.2 1 0 0 1 1 1 0 Mnd1 family Lectin_N PF03954.9 CCM00586.1 - 0.33 10.3 5.0 0.77 9.1 3.5 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain zf-rbx1 PF12678.2 CCM00586.1 - 0.38 10.9 9.5 0.73 9.9 6.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger AAA_13 PF13166.1 CCM00586.1 - 0.39 9.1 10.9 0.56 8.5 7.5 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 CCM00586.1 - 0.52 8.1 9.2 0.69 7.6 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING_6 PF14835.1 CCM00586.1 - 0.53 10.1 4.8 1.4 8.7 3.3 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF3584 PF12128.3 CCM00586.1 - 0.94 6.7 16.8 1.2 6.3 11.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 CCM00586.1 - 1.4 8.8 20.0 31 4.5 14.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) FemAB PF02388.11 CCM00586.1 - 1.5 7.3 7.3 2.1 6.9 5.0 1.1 1 0 0 1 1 1 0 FemAB family TMCO5 PF14992.1 CCM00586.1 - 1.5 7.8 12.2 2.2 7.3 8.4 1.2 1 0 0 1 1 1 0 TMCO5 family DUF4407 PF14362.1 CCM00586.1 - 1.6 7.5 8.4 2.5 6.9 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF966 PF06136.8 CCM00586.1 - 1.7 7.9 14.3 3 7.1 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) IBR PF01485.16 CCM00586.1 - 1.7 8.5 7.8 2.9 7.8 4.6 2.0 1 1 0 1 1 1 0 IBR domain DUF342 PF03961.8 CCM00586.1 - 2.1 6.6 9.1 2.8 6.2 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CytochromB561_N PF09786.4 CCM00586.1 - 2.4 6.5 9.2 3.4 5.9 6.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal zf-RING_UBOX PF13445.1 CCM00586.1 - 3 7.6 6.9 1.7 8.4 2.9 2.1 1 1 1 2 2 2 0 RING-type zinc-finger CENP-Q PF13094.1 CCM00586.1 - 4 7.4 19.2 27 4.7 13.2 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Presenilin PF01080.12 CCM00586.1 - 4.8 5.9 12.8 7 5.3 8.9 1.2 1 0 0 1 1 1 0 Presenilin zf-RING_4 PF14570.1 CCM00586.1 - 8.9 5.9 8.5 34 4.1 5.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Lge1 PF11488.3 CCM00586.1 - 9.1 6.5 15.2 1.3e+02 2.8 10.5 2.3 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Actin PF00022.14 CCM00587.1 - 2.9e-30 105.0 0.0 1.2e-13 50.2 0.0 3.1 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.8 CCM00587.1 - 0.00071 18.2 0.1 0.0064 15.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FAT PF02259.18 CCM00588.1 - 2.3e-120 401.7 6.4 2.3e-120 401.7 4.4 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 CCM00588.1 - 2.4e-54 184.3 0.6 5.2e-54 183.2 0.4 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 CCM00588.1 - 1e-44 152.2 0.3 1e-44 152.2 0.2 4.5 5 0 0 5 5 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 CCM00588.1 - 2.7e-36 123.6 0.2 2.7e-36 123.6 0.1 3.6 3 0 0 3 3 2 1 Rapamycin binding domain HEAT_2 PF13646.1 CCM00588.1 - 1.1e-19 70.4 12.4 0.0078 16.4 0.1 10.7 4 2 6 11 11 11 7 HEAT repeats FATC PF02260.15 CCM00588.1 - 2e-15 55.9 0.5 4.3e-15 54.8 0.4 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 CCM00588.1 - 4.4e-12 44.9 12.1 0.51 10.5 0.0 10.7 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 CCM00588.1 - 3.2e-07 30.6 24.6 0.013 15.9 0.0 11.4 11 3 3 14 14 11 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCM00588.1 - 5.4e-06 26.7 0.9 16 5.9 0.0 7.6 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CCM00588.1 - 1.1e-05 24.8 4.4 1.2 8.4 0.0 5.8 7 0 0 7 7 7 2 CLASP N terminal TPR_19 PF14559.1 CCM00588.1 - 1.3e-05 25.4 0.7 0.025 14.9 0.0 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM00588.1 - 0.0001 21.8 3.1 0.011 15.4 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCM00588.1 - 0.00012 21.6 0.6 3.6 7.7 0.1 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF2435 PF10363.4 CCM00588.1 - 0.0029 17.4 0.4 0.11 12.4 0.0 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) TPR_11 PF13414.1 CCM00588.1 - 0.0039 16.8 3.9 0.19 11.4 0.1 4.2 4 0 0 4 4 4 1 TPR repeat Apc3 PF12895.2 CCM00588.1 - 0.011 15.9 0.8 1.4 9.0 0.1 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CCM00588.1 - 0.028 15.1 2.2 0.54 11.0 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCM00588.1 - 0.058 13.3 3.3 5.9 6.8 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat SQS_PSY PF00494.14 CCM00589.1 - 7.2e-37 127.1 0.1 9.2e-37 126.7 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RCC1 PF00415.13 CCM00590.1 - 9.5e-34 115.3 15.2 4e-12 46.1 0.1 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCM00590.1 - 7.7e-18 63.6 29.9 2.4e-06 26.9 1.1 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 CCM00590.1 - 1.1e-11 44.2 6.4 1.1e-11 44.2 4.5 2.8 4 0 0 4 4 4 1 PHD-finger C1_1 PF00130.17 CCM00590.1 - 0.0097 15.6 2.2 0.012 15.3 0.1 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CCM00590.1 - 0.25 11.1 10.5 0.037 13.7 1.8 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 InvH PF04741.7 CCM00591.1 - 0.074 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein F-box-like PF12937.2 CCM00592.1 - 4e-08 32.8 0.7 1.8e-07 30.7 0.5 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM00592.1 - 0.016 14.8 0.5 0.016 14.8 0.3 3.5 3 1 0 3 3 3 0 F-box domain DUF4383 PF14325.1 CCM00593.1 - 0.0079 16.1 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) Methyltransf_15 PF09445.5 CCM00594.1 - 7.5e-36 123.1 0.0 1.3e-27 96.3 0.0 2.2 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CCM00594.1 - 3.8e-12 46.2 0.1 6.1e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00594.1 - 1.6e-09 38.3 0.0 4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM00594.1 - 5.7e-07 29.8 0.0 1.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CCM00594.1 - 5.8e-07 29.3 0.0 1.2e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 CCM00594.1 - 2.3e-06 27.2 0.0 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CCM00594.1 - 2.2e-05 24.1 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 CCM00594.1 - 4.9e-05 22.8 0.0 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 CCM00594.1 - 0.0009 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CCM00594.1 - 0.004 15.8 0.0 0.0056 15.4 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.8 CCM00594.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.21 CCM00594.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RRM_1 PF00076.17 CCM00595.1 - 6e-05 22.5 0.0 0.00014 21.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM00595.1 - 6.2e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_M28 PF04389.12 CCM00596.1 - 4e-25 88.5 0.1 6.9e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 MFS_1 PF07690.11 CCM00597.1 - 3.5e-21 75.3 32.7 3.5e-21 75.3 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.26 CCM00598.1 - 0.00022 21.1 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain FAD_binding_3 PF01494.14 CCM00599.1 - 4.9e-20 71.8 1.0 1.9e-11 43.6 0.8 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CCM00599.1 - 6.9e-06 25.9 2.3 0.0003 20.7 1.4 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCM00599.1 - 0.002 17.1 1.1 0.0056 15.6 0.7 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CCM00599.1 - 0.018 13.6 0.6 0.027 13.1 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.19 CCM00599.1 - 0.12 11.1 3.9 0.2 10.4 2.7 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 CCM00599.1 - 0.17 10.9 0.3 0.27 10.2 0.2 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 CCM00599.1 - 0.7 9.7 2.6 1.6 8.5 1.7 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GRA6 PF05084.8 CCM00600.1 - 0.039 13.4 1.1 0.065 12.7 0.8 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Lamp PF01299.12 CCM00600.1 - 0.043 12.9 0.4 0.07 12.2 0.3 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Herpes_gE PF02480.11 CCM00600.1 - 0.17 10.1 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RCR PF12273.3 CCM00600.1 - 0.3 11.6 0.1 0.3 11.6 0.1 2.6 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 CCM00600.1 - 0.67 9.4 2.6 1.1 8.8 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) RCR PF12273.3 CCM00601.1 - 7.1e-06 26.6 0.8 1.1e-05 26.0 0.5 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 CCM00601.1 - 0.00032 19.9 3.2 0.00065 18.9 2.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 CCM00601.1 - 0.00038 18.8 0.6 0.0005 18.4 0.3 1.5 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 CCM00601.1 - 0.001 19.2 0.6 0.001 19.2 0.4 1.6 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 CCM00601.1 - 0.0089 15.5 6.0 0.02 14.4 4.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Sec66 PF09802.4 CCM00601.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 EphA2_TM PF14575.1 CCM00601.1 - 0.018 15.4 1.0 0.031 14.6 0.1 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.1 CCM00601.1 - 0.025 14.2 2.1 0.088 12.4 1.5 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 ATG22 PF11700.3 CCM00601.1 - 0.1 11.0 0.4 0.12 10.8 0.3 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Syndecan PF01034.15 CCM00601.1 - 0.1 12.2 0.8 0.18 11.4 0.6 1.3 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 CCM00601.1 - 0.16 10.7 0.4 0.23 10.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Amnionless PF14828.1 CCM00601.1 - 0.17 10.3 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 Amnionless Rifin_STEVOR PF02009.11 CCM00601.1 - 0.3 10.6 1.6 0.44 10.1 1.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family NAD_kinase PF01513.16 CCM00603.1 - 6.5e-68 228.5 0.0 1.3e-67 227.5 0.0 1.5 1 0 0 1 1 1 1 ATP-NAD kinase DUF2419 PF10343.4 CCM00604.1 - 0.14 11.4 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2419) HMG_box PF00505.14 CCM00606.1 - 1.1e-12 47.9 2.9 1.1e-12 47.9 2.0 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM00606.1 - 0.00015 22.0 2.1 0.00015 22.0 1.5 2.3 1 1 1 2 2 2 1 HMG-box domain Pkinase PF00069.20 CCM00607.1 - 0.00026 20.2 0.1 0.004 16.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 CCM00607.1 - 0.058 13.1 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family COesterase PF00135.23 CCM00612.1 - 1.4e-74 251.7 0.0 1.9e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family ADH_zinc_N PF00107.21 CCM00612.1 - 5.2e-12 45.4 0.0 1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM00612.1 - 2.3e-11 43.4 0.0 5.6e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_3 PF07859.8 CCM00612.1 - 9.3e-08 31.8 0.0 9.3e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM00612.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCM00612.1 - 0.037 13.7 0.5 0.22 11.2 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 CCM00613.1 - 2.5e-99 333.2 0.0 3.2e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCM00613.1 - 0.013 15.4 0.0 0.22 11.3 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 CCM00615.1 - 5.9e-05 22.6 0.2 0.00031 20.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM00615.1 - 0.0032 17.0 0.7 1.1 9.0 0.0 4.4 4 1 0 4 4 4 1 F-box domain zf-RING_2 PF13639.1 CCM00616.1 - 7.7e-14 51.2 3.6 1.2e-13 50.6 2.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCM00616.1 - 8.8e-09 35.2 2.8 1.4e-08 34.6 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCM00616.1 - 4.1e-08 33.2 3.0 7.2e-08 32.4 2.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCM00616.1 - 1.3e-07 31.1 1.8 2.1e-07 30.4 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCM00616.1 - 2.9e-07 30.0 2.0 4.5e-07 29.4 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM00616.1 - 7.7e-07 28.7 2.5 1.2e-06 28.1 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CCM00616.1 - 0.00077 19.2 1.4 0.0014 18.4 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 CCM00616.1 - 0.0072 16.3 2.3 0.013 15.4 1.6 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_4 PF14570.1 CCM00616.1 - 0.038 13.5 4.4 0.069 12.7 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 CCM00616.1 - 0.087 12.8 4.2 0.15 12.1 2.9 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 CCM00616.1 - 0.22 11.2 1.6 0.59 9.8 1.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Melibiase PF02065.13 CCM00618.1 - 1e-11 44.1 0.0 6.7e-09 34.9 0.0 2.7 2 1 1 3 3 3 2 Melibiase AMP-binding PF00501.23 CCM00619.1 - 2.1e-82 276.7 0.0 2.7e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCM00619.1 - 7.3e-15 55.6 0.1 2.6e-14 53.9 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 CCM00620.1 - 6.4e-47 160.1 0.0 6.3e-43 146.9 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 DUF3184 PF11380.3 CCM00622.1 - 0.0027 15.7 3.2 0.015 13.2 0.3 2.6 1 1 0 2 2 2 1 Protein of unknown function (DUF3184) FIST PF08495.5 CCM00623.1 - 4e-05 22.8 0.0 9e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 FIST N domain Peptidase_M20 PF01546.23 CCM00624.1 - 1.1e-21 77.2 0.0 2.6e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 CCM00624.1 - 6e-21 73.4 7.1 9.3e-09 34.8 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.9 CCM00624.1 - 8.2e-13 48.0 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 CCM00624.1 - 3.8e-06 25.3 0.3 0.002 16.3 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CCM00624.1 - 0.059 13.6 0.3 14 6.1 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain ABC_tran PF00005.22 CCM00626.1 - 1.7e-29 102.8 0.1 2.9e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCM00626.1 - 1.1e-05 24.8 1.3 0.007 15.6 0.1 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCM00626.1 - 0.00011 22.2 0.4 0.016 15.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM00626.1 - 0.00021 21.3 0.7 0.00033 20.6 0.5 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CCM00626.1 - 0.0004 19.8 0.0 0.0042 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CCM00626.1 - 0.0063 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 CCM00626.1 - 0.0065 15.9 0.9 0.27 10.6 0.0 2.1 1 1 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 CCM00626.1 - 0.0077 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCM00626.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CCM00626.1 - 0.017 15.1 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 CCM00626.1 - 0.039 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 CCM00626.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase GvpD PF07088.6 CCM00626.1 - 0.059 11.6 0.0 0.12 10.6 0.0 1.4 1 0 0 1 1 1 0 GvpD gas vesicle protein IstB_IS21 PF01695.12 CCM00626.1 - 0.091 12.1 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 CCM00626.1 - 0.12 13.1 0.1 0.21 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCM00626.1 - 0.18 11.9 1.7 3.7 7.6 1.2 2.3 1 1 0 1 1 1 0 AAA domain LRR_4 PF12799.2 CCM00627.1 - 0.12 12.0 1.9 13 5.5 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) AP_endonuc_2 PF01261.19 CCM00629.1 - 3e-22 78.9 0.0 4.8e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel TENA_THI-4 PF03070.11 CCM00630.1 - 0.0022 17.7 0.3 0.036 13.8 0.2 2.2 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Kelch_4 PF13418.1 CCM00631.1 - 4.3e-27 93.6 10.0 6.3e-06 25.8 0.1 6.4 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 CCM00631.1 - 1.1e-25 89.1 8.0 1e-07 31.9 0.1 6.6 7 0 0 7 7 7 3 Galactose oxidase, central domain DUF4110 PF13422.1 CCM00631.1 - 1.7e-20 72.6 0.0 1.7e-20 72.6 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.20 CCM00631.1 - 3.4e-19 68.1 6.1 3.5e-06 26.4 0.1 5.0 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 CCM00631.1 - 4.6e-18 64.5 9.3 1.8e-05 24.6 0.0 5.0 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.1 CCM00631.1 - 1.3e-14 53.7 8.4 0.00064 19.6 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 CCM00631.1 - 4.9e-13 48.2 9.7 6.9e-05 22.4 0.0 5.7 5 1 0 5 5 5 3 Kelch motif NARP1 PF12569.3 CCM00631.1 - 6.3 5.4 10.2 11 4.6 7.1 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Abi PF02517.11 CCM00632.1 - 1.7e-06 28.0 0.8 1.7e-06 28.0 0.5 2.2 2 2 0 2 2 2 1 CAAX protease self-immunity DUF2371 PF10177.4 CCM00632.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) TENA_THI-4 PF03070.11 CCM00634.1 - 2.5e-07 30.6 0.4 1e-06 28.6 0.3 1.9 1 1 0 1 1 1 1 TENA/THI-4/PQQC family GST_N_2 PF13409.1 CCM00635.1 - 5e-23 80.8 0.0 1.1e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM00635.1 - 1.3e-14 53.8 0.0 2.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCM00635.1 - 2.8e-10 40.0 0.0 4.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCM00635.1 - 1.7e-05 25.1 0.0 3.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCM00635.1 - 0.0001 22.4 0.0 0.0029 17.7 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sporozoite_P67 PF05642.6 CCM00636.1 - 0.17 9.7 3.6 0.18 9.6 2.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ubiquitin PF00240.18 CCM00638.1 - 1.2e-16 59.8 0.0 2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCM00638.1 - 1e-08 34.7 0.0 1.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCM00638.1 - 0.0026 17.9 0.0 0.0075 16.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.5 CCM00638.1 - 0.038 14.5 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD CHCH PF06747.8 CCM00639.1 - 0.00098 18.9 3.2 0.0014 18.4 2.3 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CCM00639.1 - 0.0012 18.5 1.0 0.0018 17.9 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 CCM00639.1 - 0.0017 18.2 0.3 0.0022 17.9 0.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 CCM00639.1 - 0.0086 16.1 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 CCM00639.1 - 2.2 8.3 5.4 1.4 8.9 1.4 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb PX PF00787.19 CCM00641.1 - 2.3e-19 69.2 0.0 4.4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 CCM00641.1 - 6.9e-12 45.1 0.7 6.3e-11 41.9 0.5 2.0 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein Topoisom_I_N PF02919.10 CCM00641.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment malic PF00390.14 CCM00643.1 - 2.7e-20 72.7 0.0 3.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.10 CCM00644.1 - 1.1e-82 277.4 0.0 1.4e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CCM00644.1 - 2.9e-29 101.9 0.0 4.3e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Acyl-CoA_dh_1 PF00441.19 CCM00645.1 - 7.2e-07 29.4 0.2 7.2e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 CCM00646.1 - 5.4e-39 133.9 56.6 2.8e-31 108.5 11.2 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 CCM00646.1 - 3.6e-06 25.4 8.6 3.6e-06 25.4 6.0 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCM00646.1 - 1e-05 24.3 11.1 1e-05 24.3 7.7 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 CCM00646.1 - 0.23 9.7 30.8 0.39 9.0 12.0 3.0 1 1 2 3 3 3 0 MFS/sugar transport protein E1-E2_ATPase PF00122.15 CCM00646.1 - 2.8 6.9 7.5 18 4.2 5.2 2.3 1 1 0 1 1 1 0 E1-E2 ATPase Mmp37 PF09139.6 CCM00647.1 - 3.2e-103 345.2 0.0 3.8e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 PDZ_2 PF13180.1 CCM00648.1 - 0.034 14.0 0.0 0.08 12.8 0.0 1.7 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.19 CCM00648.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) NDK PF00334.14 CCM00649.1 - 1.3e-17 63.8 0.0 2.9e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Thi4 PF01946.12 CCM00650.1 - 7.6e-93 309.8 0.4 9.1e-93 309.5 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CCM00650.1 - 2.6e-11 43.0 0.9 7.7e-11 41.4 0.2 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM00650.1 - 3.5e-08 32.7 0.5 1.3e-07 30.8 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CCM00650.1 - 1.1e-07 31.7 0.1 2.6e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCM00650.1 - 5.8e-07 29.5 0.5 1.3e-06 28.4 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCM00650.1 - 1e-06 27.8 1.6 9.9e-06 24.6 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 CCM00650.1 - 1.3e-06 28.2 0.2 4.7e-05 23.2 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 CCM00650.1 - 7.6e-05 21.3 0.7 0.00016 20.3 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 CCM00650.1 - 0.00012 21.2 0.4 0.00018 20.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCM00650.1 - 0.00037 20.6 1.0 0.00055 20.0 0.2 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCM00650.1 - 0.00067 18.6 0.3 0.016 14.0 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 CCM00650.1 - 0.027 14.8 0.2 0.073 13.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCM00650.1 - 0.045 12.3 0.3 0.066 11.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.14 CCM00650.1 - 0.058 12.5 0.1 0.72 8.9 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Shikimate_DH PF01488.15 CCM00650.1 - 0.059 13.4 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 CCM00650.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase CM_2 PF01817.16 CCM00651.1 - 1.5e-10 41.0 0.1 5.2e-07 29.6 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II RPAP1_N PF08621.5 CCM00651.1 - 3.4 7.3 5.1 7.7 6.2 0.1 3.3 4 0 0 4 4 4 0 RPAP1-like, N-terminal Septin PF00735.13 CCM00652.1 - 1.1e-44 152.5 0.0 6.2e-17 61.5 0.0 3.9 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.18 CCM00652.1 - 0.00092 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCM00652.1 - 0.0025 17.2 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCM00652.1 - 0.0027 17.5 0.3 0.32 10.7 0.1 2.4 1 1 0 2 2 2 1 Dynamin family Miro PF08477.8 CCM00652.1 - 0.0032 17.9 0.0 0.0066 16.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 CCM00652.1 - 0.016 15.2 0.3 0.12 12.2 0.1 2.4 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 CCM00652.1 - 0.019 14.9 0.1 0.054 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CCM00652.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 CCM00652.1 - 0.055 12.0 0.0 0.096 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.7 CCM00652.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.9 CCM00652.1 - 0.12 12.1 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 CCM00653.1 - 1.1e-28 100.0 0.0 5.5e-10 38.7 0.0 3.2 3 0 0 3 3 3 3 Septin Zn_clus PF00172.13 CCM00653.1 - 1.5e-09 37.5 11.8 2.7e-09 36.7 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.1 CCM00654.1 - 1.1e-44 150.1 0.0 5e-10 39.2 0.0 10.5 7 3 5 12 12 12 7 PPR repeat family PPR_3 PF13812.1 CCM00654.1 - 8.5e-41 134.8 15.8 0.00013 21.9 0.0 15.1 16 0 0 16 16 14 8 Pentatricopeptide repeat domain PPR PF01535.15 CCM00654.1 - 1.2e-36 122.0 0.1 0.013 15.4 0.0 14.7 15 0 0 15 15 15 7 PPR repeat PPR_1 PF12854.2 CCM00654.1 - 1.3e-17 62.9 0.0 0.003 17.0 0.0 9.8 11 0 0 11 11 11 4 PPR repeat TPR_14 PF13428.1 CCM00654.1 - 1.1e-10 41.2 9.7 0.2 12.3 0.0 8.7 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCM00654.1 - 2.2e-05 24.9 7.1 0.29 11.8 0.0 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM00654.1 - 0.00018 21.4 0.0 0.2 11.6 0.0 3.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM00654.1 - 0.0015 18.1 0.2 40 4.3 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ECSIT PF06239.6 CCM00654.1 - 0.0028 16.5 0.0 0.61 8.9 0.0 3.4 3 1 1 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway Clathrin PF00637.15 CCM00654.1 - 0.0076 15.8 0.0 0.64 9.6 0.0 3.3 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_6 PF13174.1 CCM00654.1 - 0.025 15.0 0.2 1.5 9.4 0.0 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP13 PF12921.2 CCM00654.1 - 0.048 13.0 0.0 42 3.5 0.0 4.0 3 1 0 3 3 3 0 Mitochondrial ATPase expression XPG_I_2 PF12813.2 CCM00654.1 - 0.062 12.7 0.1 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 XPG domain containing DUF1574 PF07611.6 CCM00654.1 - 0.096 11.5 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) TPR_10 PF13374.1 CCM00654.1 - 1.5 8.8 10.6 28 4.8 0.5 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Velvet PF11754.3 CCM00655.1 - 6e-46 156.6 0.0 2.8e-17 62.9 0.0 3.2 3 0 0 3 3 3 3 Velvet factor ArfGap PF01412.13 CCM00656.1 - 5.8e-29 100.2 0.0 1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf F-box PF00646.28 CCM00657.1 - 9.7e-06 25.1 0.3 2.7e-05 23.6 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCM00657.1 - 0.00017 21.2 0.9 0.00017 21.2 0.6 2.4 4 0 0 4 4 4 1 F-box-like UCH PF00443.24 CCM00658.1 - 1.1e-48 165.7 0.0 9.6e-48 162.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM00658.1 - 2.9e-20 72.8 0.0 7.7e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2 PF00096.21 CCM00658.1 - 8.1e-07 29.0 46.8 0.001 19.2 0.7 6.3 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCM00658.1 - 8.9e-05 22.5 33.2 0.0046 17.1 0.5 6.0 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCM00658.1 - 0.0014 18.8 1.4 0.0014 18.8 1.0 6.0 6 0 0 6 6 6 2 C2H2-type zinc finger zf-met PF12874.2 CCM00658.1 - 0.091 12.9 28.4 0.081 13.1 0.7 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type PP2C PF00481.16 CCM00659.1 - 2.6e-26 92.5 0.0 9.6e-24 84.1 0.0 2.7 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCM00659.1 - 0.00043 19.7 0.0 0.0022 17.4 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SKG6 PF08693.5 CCM00660.1 - 0.77 9.1 6.2 0.24 10.7 1.0 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Yip1 PF04893.12 CCM00661.1 - 0.00019 20.9 0.6 0.00031 20.2 0.4 1.3 1 0 0 1 1 1 1 Yip1 domain DUF3635 PF12330.3 CCM00662.1 - 7.4e-19 67.6 0.0 1.5e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Sld5 PF05916.6 CCM00663.1 - 1.2e-18 67.3 0.1 1.9e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein FAM150 PF15129.1 CCM00663.1 - 0.014 15.2 0.0 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 FAM150 family P21-Arc PF04062.9 CCM00665.1 - 2.9e-76 255.1 0.0 3.2e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NOB1_Zn_bind PF08772.6 CCM00666.1 - 7.2e-28 96.2 0.3 1.3e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 CCM00666.1 - 1 8.6 6.0 2.5 7.4 4.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Iso_dh PF00180.15 CCM00667.1 - 1.8e-124 415.2 0.0 2.1e-124 414.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Vps5 PF09325.5 CCM00668.1 - 4.2e-19 68.7 2.3 6e-19 68.2 1.6 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CCM00668.1 - 1.3e-10 41.0 0.1 3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 PX domain GTP_cyclohydro2 PF00925.15 CCM00669.1 - 6.1e-65 217.5 0.0 1.9e-59 199.7 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II Peptidase_M28 PF04389.12 CCM00672.1 - 1.7e-14 53.9 0.0 6.4e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CCM00672.1 - 1.8e-11 43.7 0.0 4.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CCM00672.1 - 6.6e-06 25.7 0.1 1.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 CCM00672.1 - 0.018 14.3 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.11 CCM00673.1 - 2.5e-42 144.8 54.1 2.5e-42 144.8 37.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM00673.1 - 6.8e-18 64.4 7.6 6.8e-18 64.4 5.3 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter SKN1 PF03935.10 CCM00674.1 - 2.5e-180 599.9 1.5 2.9e-180 599.7 1.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) MFS_1 PF07690.11 CCM00675.1 - 2.4e-17 62.7 50.8 1.3e-12 47.1 7.5 3.0 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM00675.1 - 1.7e-07 30.1 5.2 1.7e-07 30.1 3.6 2.8 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 CCM00675.1 - 0.011 15.4 1.5 0.067 12.9 0.5 2.6 2 0 0 2 2 2 0 MFS_1 like family DUF2975 PF11188.3 CCM00675.1 - 0.038 13.6 0.7 0.038 13.6 0.5 4.8 4 2 3 7 7 7 0 Protein of unknown function (DUF2975) Pex14_N PF04695.8 CCM00676.1 - 1.2e-11 44.7 4.8 3.1e-11 43.4 0.0 2.8 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region adh_short PF00106.20 CCM00677.1 - 1.4e-17 64.1 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM00677.1 - 5.2e-06 26.2 0.0 2.2e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM00677.1 - 0.059 13.1 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ACT_7 PF13840.1 CCM00678.1 - 1.8e-20 72.1 0.0 6e-13 48.1 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 CCM00678.1 - 0.0042 16.5 0.0 2.1 7.8 0.0 2.9 2 0 0 2 2 2 2 ACT domain adh_short PF00106.20 CCM00681.1 - 2.4e-29 102.4 0.3 6.2e-29 101.0 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM00681.1 - 1.3e-12 47.7 0.5 2.2e-11 43.7 0.3 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM00681.1 - 8.6e-11 42.0 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM00681.1 - 0.0049 16.9 0.0 0.022 14.7 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Asparaginase_2 PF01112.13 CCM00684.1 - 8.7e-58 195.5 0.0 1.5e-43 148.7 0.0 2.3 2 1 0 2 2 2 2 Asparaginase Glyco_hydro_10 PF00331.15 CCM00685.1 - 3.1e-90 302.4 0.0 4.1e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 CCM00685.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like GST_N_3 PF13417.1 CCM00686.1 - 4.7e-14 52.3 0.0 1.1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM00686.1 - 1.9e-12 47.0 0.0 5.7e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCM00686.1 - 0.0019 18.3 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM00686.1 - 0.0031 17.3 0.3 0.0068 16.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCM00686.1 - 0.04 13.8 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_10 PF00331.15 CCM00687.1 - 1.1e-95 320.3 0.0 1.4e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF1615 PF07759.7 CCM00687.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Glyco_hydro_10 PF00331.15 CCM00688.1 - 2.3e-71 240.4 0.0 9.5e-57 192.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 Abhydrolase_6 PF12697.2 CCM00689.1 - 3.4e-12 46.7 3.4 3.3e-11 43.5 2.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM00689.1 - 0.003 17.3 0.0 0.0066 16.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dynamitin PF04912.9 CCM00690.1 - 5.2e-22 78.1 14.6 2.1e-13 49.8 0.2 3.9 3 1 0 3 3 3 2 Dynamitin Apolipoprotein PF01442.13 CCM00690.1 - 1e-05 25.1 4.6 1e-05 25.1 3.2 2.4 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 CCM00690.1 - 0.00051 19.8 0.2 0.45 10.3 0.0 3.7 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CCM00690.1 - 0.00089 18.5 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Reovirus sigma C capsid protein NPV_P10 PF05531.7 CCM00690.1 - 0.00093 19.4 3.4 2.6 8.3 0.3 4.7 3 1 1 4 4 4 1 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 CCM00690.1 - 0.0061 13.9 2.0 0.013 12.9 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Spc7 PF08317.6 CCM00690.1 - 0.0069 15.0 5.1 0.014 14.1 1.5 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein Fmp27_WPPW PF10359.4 CCM00690.1 - 0.0077 14.7 2.4 2.1 6.6 0.0 3.0 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 CCM00690.1 - 0.011 15.3 0.5 0.011 15.3 0.3 3.1 3 1 0 4 4 3 0 IncA protein TBPIP PF07106.8 CCM00690.1 - 0.013 15.0 3.6 0.7 9.4 1.6 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-Q PF13094.1 CCM00690.1 - 0.015 15.3 5.2 0.015 15.3 3.6 3.5 1 1 3 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2884 PF11101.3 CCM00690.1 - 0.016 14.6 0.5 0.034 13.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF2317 PF10079.4 CCM00690.1 - 0.032 12.8 0.3 0.053 12.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) PspA_IM30 PF04012.7 CCM00690.1 - 0.042 13.2 9.6 0.36 10.1 1.1 3.6 2 1 1 3 3 3 0 PspA/IM30 family Prefoldin_2 PF01920.15 CCM00690.1 - 0.042 13.6 6.3 44 3.9 4.8 3.9 3 1 0 3 3 3 0 Prefoldin subunit Prefoldin_3 PF13758.1 CCM00690.1 - 0.046 13.4 4.6 0.12 12.1 2.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit YPEB PF14620.1 CCM00690.1 - 0.055 12.4 1.8 0.3 10.0 0.2 2.5 3 0 0 3 3 3 0 YpeB sporulation Hemagglutinin PF00509.13 CCM00690.1 - 0.069 11.2 0.5 0.1 10.6 0.4 1.2 1 0 0 1 1 1 0 Haemagglutinin DUF1664 PF07889.7 CCM00690.1 - 0.083 12.6 4.2 0.055 13.2 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 CCM00690.1 - 0.097 13.0 13.7 4 7.8 0.6 4.9 4 1 1 5 5 5 0 SlyX Cep57_MT_bd PF06657.8 CCM00690.1 - 0.11 12.5 6.8 1.3 9.0 0.1 2.8 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 AAA_13 PF13166.1 CCM00690.1 - 0.13 10.7 1.6 0.57 8.5 0.5 2.0 2 0 0 2 2 2 0 AAA domain Herpes_UL25 PF01499.11 CCM00690.1 - 0.15 10.3 4.6 0.14 10.3 0.9 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family Laminin_II PF06009.7 CCM00690.1 - 0.16 11.7 10.0 0.14 11.9 2.0 3.4 4 1 0 4 4 3 0 Laminin Domain II ATG16 PF08614.6 CCM00690.1 - 0.2 11.4 10.6 0.37 10.5 0.6 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Spc24 PF08286.6 CCM00690.1 - 0.25 11.0 3.9 3 7.5 0.9 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.7 CCM00690.1 - 0.25 11.0 11.0 0.068 12.9 2.1 2.7 3 0 0 3 3 2 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.20 CCM00690.1 - 0.35 11.0 5.9 0.52 10.5 0.7 3.1 3 0 0 3 3 3 0 Syntaxin BLOC1_2 PF10046.4 CCM00690.1 - 0.38 10.9 3.7 5.3 7.2 0.5 3.5 3 1 1 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cortex-I_coil PF09304.5 CCM00690.1 - 0.63 10.1 12.9 1.5 8.9 5.1 3.0 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF1319 PF07028.6 CCM00690.1 - 0.76 9.9 10.0 0.1 12.7 1.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) MtrB PF05440.7 CCM00690.1 - 0.82 9.7 4.5 11 6.1 0.2 3.7 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B CorA PF01544.13 CCM00690.1 - 1 8.3 8.8 1.2 8.0 1.5 3.0 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.6 CCM00690.1 - 1.2 9.5 9.0 3.1 8.2 1.9 3.9 3 2 2 5 5 4 0 Syntaxin 6, N-terminal HrpB7 PF09486.5 CCM00690.1 - 1.2 8.9 10.3 2.8 7.8 2.2 3.2 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) APG6 PF04111.7 CCM00690.1 - 1.3 8.0 4.9 2.6 7.0 2.3 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 COG2 PF06148.6 CCM00690.1 - 1.3 8.8 7.0 6.6 6.6 2.4 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Hemerythrin PF01814.18 CCM00690.1 - 1.7 8.8 6.8 2.8 8.1 1.5 3.2 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Uds1 PF15456.1 CCM00690.1 - 2.2 8.2 14.6 9.1 6.2 0.1 4.5 4 1 0 4 4 4 0 Up-regulated During Septation MutS_III PF05192.13 CCM00690.1 - 2.3 7.9 9.0 51 3.5 4.1 3.0 1 1 0 2 2 2 0 MutS domain III ALIX_LYPXL_bnd PF13949.1 CCM00690.1 - 2.5 7.0 9.2 0.5 9.2 0.6 2.8 3 0 0 3 3 3 0 ALIX V-shaped domain binding to HIV Atg14 PF10186.4 CCM00690.1 - 2.9 6.7 6.8 3 6.6 2.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 CCM00690.1 - 5.2 7.0 12.3 6.9 6.6 2.9 4.0 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 CCM00690.1 - 9 6.4 6.2 3.8 7.6 0.8 2.8 4 1 0 4 4 1 0 Fibrinogen alpha/beta chain family dsrm PF00035.20 CCM00691.1 - 0.0016 18.9 0.0 0.002 18.6 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif Chitin_synth_2 PF03142.10 CCM00692.1 - 4.3e-224 744.8 0.0 6.3e-224 744.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CCM00692.1 - 4.4e-12 46.1 7.6 4.4e-12 46.1 5.3 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCM00692.1 - 2e-10 40.8 0.0 3.9e-08 33.3 0.0 2.7 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CCM00692.1 - 2.6e-09 36.7 0.0 4.8e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CCM00692.1 - 0.028 14.1 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCM00692.1 - 0.097 11.9 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 DSPc PF00782.15 CCM00693.1 - 2.4e-05 23.9 0.0 5.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 CCM00693.1 - 0.001 18.5 0.4 0.0025 17.3 0.3 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 CCM00693.1 - 0.002 17.5 1.2 0.064 12.5 0.0 2.9 3 0 0 3 3 3 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCM00693.1 - 0.044 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF2281 PF10047.4 CCM00693.1 - 0.16 12.2 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Abhydrolase_6 PF12697.2 CCM00694.1 - 1.2e-08 35.1 0.1 1.5e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM00694.1 - 0.0072 16.0 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family TPR_11 PF13414.1 CCM00695.1 - 2.2e-48 161.7 35.1 1.2e-10 40.8 0.8 13.6 12 3 3 15 15 14 11 TPR repeat TPR_16 PF13432.1 CCM00695.1 - 2.9e-42 142.5 58.4 6.1e-08 33.1 0.7 15.3 10 4 5 16 16 16 9 Tetratricopeptide repeat TPR_2 PF07719.12 CCM00695.1 - 4.5e-33 110.4 37.7 9.9e-07 28.2 0.4 18.0 17 0 0 17 17 17 8 Tetratricopeptide repeat TPR_14 PF13428.1 CCM00695.1 - 6.3e-30 100.9 71.2 0.0012 19.3 1.1 20.8 13 7 10 24 24 24 9 Tetratricopeptide repeat TPR_19 PF14559.1 CCM00695.1 - 2e-29 101.6 44.8 6.1e-05 23.2 1.2 13.2 11 4 3 14 14 13 7 Tetratricopeptide repeat TPR_1 PF00515.23 CCM00695.1 - 4.5e-27 92.5 25.9 5.1e-07 29.0 0.1 14.7 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_8 PF13181.1 CCM00695.1 - 7.6e-26 87.9 13.4 0.0011 18.6 0.1 14.4 13 1 1 14 14 14 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCM00695.1 - 5.6e-24 82.2 13.6 0.33 11.2 0.1 16.9 18 1 0 18 18 17 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCM00695.1 - 7.3e-20 70.6 47.3 0.0016 18.3 1.3 14.0 10 4 5 16 16 16 7 Tetratricopeptide repeat Apc3 PF12895.2 CCM00695.1 - 6.1e-12 45.5 14.0 2.7e-05 24.1 0.0 9.2 8 3 2 10 10 10 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCM00695.1 - 5.9e-10 38.9 31.3 0.026 14.9 0.2 13.2 15 0 0 15 15 12 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCM00695.1 - 7.5e-10 38.5 23.4 7e-05 22.6 0.2 9.6 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM00695.1 - 7.1e-09 34.8 31.1 0.0022 17.6 0.2 12.5 15 0 0 15 15 14 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCM00695.1 - 0.00037 20.3 0.8 1 9.2 0.0 5.2 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.4 CCM00695.1 - 0.0013 18.1 0.5 3.3 7.0 0.0 4.5 4 0 0 4 4 4 1 26S proteasome subunit RPN7 Coatomer_WDAD PF04053.9 CCM00695.1 - 0.22 10.2 0.5 21 3.7 0.0 2.6 2 1 1 3 3 3 0 Coatomer WD associated region TPR_10 PF13374.1 CCM00695.1 - 0.46 10.4 28.3 0.74 9.8 0.9 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_20 PF14561.1 CCM00695.1 - 2.1 8.5 20.4 0.34 11.0 0.2 6.9 8 2 1 9 9 7 0 Tetratricopeptide repeat LETM1 PF07766.8 CCM00696.1 - 0.00016 20.8 0.1 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 LETM1-like protein DUF3275 PF11679.3 CCM00696.1 - 0.18 11.4 3.9 0.082 12.5 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) LETM1 PF07766.8 CCM00697.1 - 2.1e-15 56.5 0.9 1.2e-12 47.4 0.1 2.0 1 1 1 2 2 2 2 LETM1-like protein zf-DHHC PF01529.15 CCM00699.1 - 1.1e-26 93.2 2.4 1.1e-26 93.2 1.7 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF912 PF06024.7 CCM00699.1 - 0.065 13.2 0.0 6.5 6.8 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_US9 PF06072.6 CCM00699.1 - 4.1 7.3 5.2 25 4.7 0.1 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Aminotran_3 PF00202.16 CCM00700.1 - 4.9e-110 367.5 0.0 6.1e-110 367.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CCM00700.1 - 8.1e-05 21.8 0.0 0.00036 19.7 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase zf-DHHC PF01529.15 CCM00700.1 - 0.0012 18.3 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Aminotran_1_2 PF00155.16 CCM00700.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Fes1 PF08609.5 CCM00701.1 - 2e-23 82.7 0.3 5.2e-23 81.3 0.2 1.8 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 CCM00701.1 - 0.0055 16.9 3.8 0.02 15.1 0.4 3.0 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.17 CCM00701.1 - 0.012 15.6 2.5 7.4 6.9 0.0 4.0 4 1 1 5 5 5 0 HEAT repeat DUF1877 PF08974.5 CCM00701.1 - 0.034 13.8 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) HEAT_EZ PF13513.1 CCM00701.1 - 0.054 13.9 1.6 7.5 7.1 0.1 3.8 2 1 2 4 4 4 0 HEAT-like repeat Membr_traf_MHD PF10540.4 CCM00705.1 - 2.9e-16 59.5 0.4 1.8e-15 56.9 0.0 2.6 1 1 1 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 CCM00705.1 - 2e-11 43.5 0.0 9e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 C2 domain BP28CT PF08146.7 CCM00706.1 - 3.9e-19 68.8 0.5 1.9e-18 66.6 0.0 2.5 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CCM00706.1 - 7e-13 48.5 0.7 7e-13 48.5 0.5 3.9 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 CCM00706.1 - 0.00087 19.1 2.2 10 6.5 0.1 5.1 3 0 0 3 3 3 2 HEAT repeat HSP70 PF00012.15 CCM00707.1 - 1.4e-73 247.8 8.0 1e-72 245.0 5.6 2.2 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCM00707.1 - 8.4e-05 21.3 1.4 0.00095 17.8 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCM00707.1 - 0.00047 19.8 1.8 0.00047 19.8 1.3 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain HrpA_pilin PF09589.5 CCM00707.1 - 0.0006 20.2 1.4 0.0017 18.7 0.1 2.3 2 0 0 2 2 2 1 HrpA pilus formation protein IF-2 PF11987.3 CCM00707.1 - 1.3 8.9 4.4 0.99 9.3 0.1 2.8 4 0 0 4 4 4 0 Translation-initiation factor 2 Pkinase PF00069.20 CCM00708.1 - 2.3e-40 138.3 0.0 3.3e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00708.1 - 1.2e-29 103.2 0.0 1.8e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 CCM00708.1 - 5.4e-11 41.9 7.0 0.00026 20.7 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Kinase-like PF14531.1 CCM00708.1 - 1.1e-07 31.0 0.0 2.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PBD PF00786.23 CCM00708.1 - 7.6e-05 23.0 0.0 0.00027 21.3 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain EphA2_TM PF14575.1 CCM00709.1 - 0.066 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 CCM00709.1 - 0.21 11.2 0.1 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 CCM00709.1 - 5.1 6.4 6.8 0.22 10.8 0.2 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain NUDIX PF00293.23 CCM00710.1 - 4.8e-11 42.4 0.0 1e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain DUF4620 PF15399.1 CCM00710.1 - 0.01 15.9 0.3 0.022 14.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) DUF1289 PF06945.8 CCM00711.1 - 0.014 14.8 0.8 0.021 14.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) WD40 PF00400.27 CCM00713.1 - 2.3e-10 39.9 21.6 0.0011 18.7 0.4 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 CCM00713.1 - 0.0013 18.5 0.2 0.15 11.7 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CCM00713.1 - 0.048 13.1 0.1 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.6 CCM00713.1 - 0.071 11.9 0.3 0.76 8.6 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Aldo_ket_red PF00248.16 CCM00716.1 - 7e-34 116.9 0.0 1.2e-33 116.1 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family HA2 PF04408.18 CCM00717.1 - 2.5e-27 94.8 0.1 5.7e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCM00717.1 - 1.2e-26 92.8 0.0 6.7e-26 90.3 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCM00717.1 - 1.4e-10 40.9 0.0 4.8e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCM00717.1 - 8e-08 31.9 0.1 1.8e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 CCM00717.1 - 0.0001 21.7 0.2 0.00028 20.3 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 CCM00717.1 - 0.003 17.6 0.0 0.0099 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCM00717.1 - 0.0061 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 CCM00717.1 - 0.092 11.9 0.0 0.37 9.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 CCM00717.1 - 0.17 10.9 0.0 0.86 8.6 0.0 2.0 2 0 0 2 2 2 0 KaiC Myosin_head PF00063.16 CCM00717.1 - 0.22 9.5 0.0 0.31 9.0 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) AMP-binding PF00501.23 CCM00718.1 - 4.7e-51 173.4 0.4 3.4e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme ADH_N PF08240.7 CCM00718.1 - 2.6e-31 107.5 3.6 2.6e-31 107.5 2.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM00718.1 - 1.2e-14 53.9 0.0 2.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding_C PF13193.1 CCM00718.1 - 2.2e-10 41.3 0.2 7.4e-10 39.6 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.14 CCM00718.1 - 0.0019 17.3 0.6 0.0028 16.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N_2 PF13602.1 CCM00718.1 - 0.0082 17.0 0.0 0.027 15.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2338 PF10100.4 CCM00718.1 - 0.027 12.8 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) NAD_binding_7 PF13241.1 CCM00718.1 - 0.062 13.5 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3584 PF12128.3 CCM00719.1 - 0.39 7.9 18.0 0.57 7.4 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.6 CCM00719.1 - 0.86 10.0 11.4 6.9 7.1 3.9 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal FUSC PF04632.7 CCM00719.1 - 2.9 6.2 12.4 4.3 5.6 8.4 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family TMCO5 PF14992.1 CCM00719.1 - 4.1 6.4 9.8 8 5.5 6.8 1.5 1 0 0 1 1 1 0 TMCO5 family Nsp1_C PF05064.8 CCM00719.1 - 4.5 6.9 7.9 13 5.4 2.4 2.9 3 0 0 3 3 3 0 Nsp1-like C-terminal region GAS PF13851.1 CCM00719.1 - 8.7 5.4 16.7 52 2.9 9.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HEAT_EZ PF13513.1 CCM00720.1 - 0.016 15.6 0.1 0.45 11.0 0.0 2.7 2 1 0 2 2 2 0 HEAT-like repeat Arm PF00514.18 CCM00720.1 - 0.04 13.7 0.2 4.8 7.1 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat BCNT PF07572.7 CCM00722.1 - 1e-17 63.7 0.1 2e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development ORC5_C PF14630.1 CCM00722.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus ProRS-C_1 PF09180.6 CCM00723.1 - 1.7e-24 85.4 2.7 4e-24 84.3 1.9 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 CCM00723.1 - 2.8e-20 72.5 0.1 4.8e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCM00723.1 - 2.1e-14 53.2 0.0 5.3e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 CCM00723.1 - 2.6e-09 36.9 0.0 5.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain TraC_F_IV PF11130.3 CCM00723.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer tRNA-synt_1 PF00133.17 CCM00724.1 - 9.2e-130 433.4 0.0 1.1e-129 433.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCM00724.1 - 9.5e-14 51.4 0.3 1.9e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCM00724.1 - 1.7e-07 30.2 0.0 0.14 10.7 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) PNRC PF15365.1 CCM00724.1 - 0.034 14.1 0.1 0.098 12.6 0.1 1.8 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Cyclin_N PF00134.18 CCM00725.1 - 1.6e-44 150.5 1.0 4.7e-44 149.0 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCM00725.1 - 2.4e-26 91.9 0.1 4.8e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L19 PF01245.15 CCM00725.1 - 0.045 13.5 0.1 0.09 12.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L19 GST_N_3 PF13417.1 CCM00726.1 - 2.9e-11 43.4 0.1 4.6e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM00726.1 - 3.4e-08 33.3 0.1 5.8e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM00726.1 - 2e-05 24.4 0.1 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UCH PF00443.24 CCM00727.1 - 2.2e-43 148.3 0.0 3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM00727.1 - 1.2e-11 44.6 0.0 7.6e-06 25.5 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Aminotran_1_2 PF00155.16 CCM00728.1 - 7.8e-54 182.9 0.0 9.3e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CCM00728.1 - 0.019 13.5 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase WD40 PF00400.27 CCM00729.1 - 1.1e-74 243.8 26.1 1.1e-14 53.6 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCM00729.1 - 2.9e-11 42.6 0.1 0.035 13.6 0.0 5.3 5 0 0 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 CCM00729.1 - 9.7e-05 21.2 1.9 4.7 5.8 0.0 4.5 3 1 2 5 5 5 3 Nup133 N terminal like PD40 PF07676.7 CCM00729.1 - 0.0034 17.0 0.1 4.4 7.0 0.0 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 CCM00729.1 - 0.066 12.9 4.3 0.45 10.2 0.1 3.2 2 2 2 4 4 4 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 CCM00729.1 - 0.37 8.5 3.5 8.4 4.0 0.1 3.2 3 1 0 4 4 4 0 IKI3 family Glyco_hydro_1 PF00232.13 CCM00730.1 - 2e-158 527.3 0.5 2.2e-158 527.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 CCM00730.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core COesterase PF00135.23 CCM00731.1 - 8.6e-08 31.3 0.1 2.1e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family NST1 PF13945.1 CCM00732.1 - 1.9 8.5 12.0 0.73 9.8 0.9 3.1 3 0 0 3 3 3 0 Salt tolerance down-regulator ArgJ PF01960.13 CCM00733.1 - 1.6e-144 481.0 0.2 1.9e-144 480.8 0.2 1.0 1 0 0 1 1 1 1 ArgJ family Ribosomal_L35Ae PF01247.13 CCM00734.1 - 4.3e-42 141.8 1.0 5.2e-42 141.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CCM00734.1 - 0.0012 18.7 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Sec6 PF06046.8 CCM00735.1 - 8.7e-151 502.7 6.6 1.2e-150 502.2 2.8 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 CCM00735.1 - 0.0086 14.8 4.0 0.17 10.6 1.9 2.8 1 1 0 2 2 2 1 Vps53-like, N-terminal HECT PF00632.20 CCM00735.1 - 0.0089 15.2 0.1 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CN_hydrolase PF00795.17 CCM00736.1 - 6.3e-28 97.3 0.0 1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 CCM00736.1 - 2e-17 62.8 0.0 8.2e-17 60.9 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 CCM00736.1 - 0.0076 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase RRM_1 PF00076.17 CCM00737.1 - 1.3e-21 76.0 0.0 8.8e-12 44.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM00737.1 - 3.7e-14 52.4 0.1 9e-12 44.8 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM00737.1 - 6.2e-11 41.9 0.0 4.1e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 CCM00737.1 - 0.00054 20.3 33.2 0.00067 20.0 23.0 1.3 1 0 0 1 1 1 1 Glycine rich protein family ACC_central PF08326.7 CCM00738.1 - 3.9e-213 709.5 0.0 5.8e-213 708.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CCM00738.1 - 1.1e-164 548.4 0.0 1.4e-164 548.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CCM00738.1 - 1e-50 171.9 0.1 2.4e-50 170.7 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CCM00738.1 - 1.5e-24 86.2 0.1 3.1e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCM00738.1 - 5.7e-20 71.2 0.0 4.5e-19 68.4 0.0 2.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CCM00738.1 - 3.3e-15 55.4 0.0 6.9e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CCM00738.1 - 1.9e-10 40.8 0.1 4.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCM00738.1 - 1.8e-08 33.5 0.0 0.0024 16.6 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CCM00738.1 - 0.0021 17.4 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CCM00738.1 - 0.0027 17.5 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCM00738.1 - 0.013 15.1 0.0 0.044 13.4 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like ATP-grasp PF02222.17 CCM00738.1 - 0.039 13.3 0.1 0.083 12.2 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain Fer2_4 PF13510.1 CCM00738.1 - 0.072 12.9 0.1 0.35 10.6 0.1 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Zds_C PF08632.5 CCM00739.1 - 1.8e-22 78.4 0.4 3.3e-22 77.6 0.3 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CDC73 PF05179.9 CCM00739.1 - 0.69 9.2 4.9 0.23 10.7 0.1 2.3 2 0 0 2 2 2 0 RNA pol II accessory factor, Cdc73 family PH_10 PF15411.1 CCM00740.1 - 2.7e-26 92.0 0.0 5.5e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 CCM00740.1 - 6.5e-06 25.8 1.4 1.3e-05 24.9 0.9 1.5 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 CCM00740.1 - 0.0022 17.6 0.1 0.016 14.8 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 CCM00740.1 - 0.012 15.3 0.6 0.023 14.3 0.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCM00740.1 - 0.016 14.8 0.7 0.029 14.0 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCM00740.1 - 0.027 14.5 0.5 0.088 12.9 0.4 1.8 1 1 1 2 2 2 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CCM00740.1 - 0.43 10.6 1.1 0.93 9.5 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCM00740.1 - 0.45 10.2 0.6 0.89 9.2 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Metallophos_2 PF12850.2 CCM00741.1 - 1.3e-05 25.1 0.0 3.4e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CCM00741.1 - 0.031 13.6 0.8 0.13 11.6 0.6 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase zf-ZPR1 PF03367.8 CCM00744.1 - 2.1e-104 345.6 0.2 6.4e-53 178.2 0.0 3.2 2 1 1 3 3 3 3 ZPR1 zinc-finger domain DZR PF12773.2 CCM00744.1 - 0.067 13.0 4.0 1.6 8.6 0.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CCM00744.1 - 0.18 11.8 6.3 11 6.0 0.0 4.5 5 0 0 5 5 5 0 Zinc ribbon domain HypA PF01155.14 CCM00744.1 - 0.65 9.6 3.0 10 5.8 0.0 2.8 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 CCM00744.1 - 1.4 8.6 4.3 46 3.7 0.1 3.6 3 0 0 3 3 3 0 Putative transposase DNA-binding domain E1-E2_ATPase PF00122.15 CCM00745.1 - 2.8e-50 170.5 2.6 4.6e-50 169.8 1.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCM00745.1 - 7.4e-32 111.4 1.5 3.3e-31 109.3 0.4 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CCM00745.1 - 2.7e-27 94.6 0.0 3.4e-13 49.5 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 CCM00745.1 - 1.4e-10 41.7 0.0 4.2e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCM00745.1 - 0.0056 16.2 0.5 0.13 11.7 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Dynactin_p22 PF07426.6 CCM00746.1 - 0.004 16.4 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 bZIP_1 PF00170.16 CCM00746.1 - 0.068 13.1 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 bZIP transcription factor FUSC PF04632.7 CCM00746.1 - 7.6 4.8 6.7 9.8 4.4 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ank_2 PF12796.2 CCM00747.1 - 8.8e-08 32.3 0.0 2.9e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCM00747.1 - 9.7e-05 21.9 0.1 0.00024 20.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 CCM00747.1 - 0.0002 21.5 0.0 0.0021 18.2 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM00747.1 - 0.0016 18.4 0.0 0.0052 16.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 CCM00747.1 - 0.018 15.5 0.0 0.068 13.7 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) OPT PF03169.10 CCM00750.1 - 2.3e-186 620.9 60.5 2.6e-186 620.7 42.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SHNi-TPR PF10516.4 CCM00751.1 - 1.6e-16 59.2 0.2 1.2e-13 50.0 0.0 3.5 3 0 0 3 3 3 1 SHNi-TPR TPR_11 PF13414.1 CCM00751.1 - 1.5e-14 53.3 0.8 7e-06 25.5 0.4 2.6 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 CCM00751.1 - 1.7e-13 50.2 6.6 8e-07 28.9 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCM00751.1 - 2.9e-08 32.9 1.4 0.11 12.4 0.2 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCM00751.1 - 1e-07 31.2 0.2 0.11 12.1 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM00751.1 - 6.2e-06 26.7 14.7 0.00059 20.4 0.9 4.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 CCM00751.1 - 0.00023 21.0 0.9 1.4 8.9 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCM00751.1 - 0.0019 17.8 3.8 0.47 10.3 0.1 4.2 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCM00751.1 - 0.071 13.4 14.6 0.7 10.2 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCM00751.1 - 0.15 11.8 0.7 8.3 6.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCM00751.1 - 0.23 12.2 9.8 22 6.0 0.2 4.9 4 1 1 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 CCM00751.1 - 2.7 7.9 8.3 2.9 7.8 0.3 3.8 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain Aldedh PF00171.17 CCM00752.1 - 4.8e-13 48.2 5.8 3.4e-09 35.5 3.5 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family ANTH PF07651.11 CCM00755.1 - 1e-50 172.0 0.1 2.2e-50 170.9 0.0 1.6 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 CCM00755.1 - 8.5e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 CCM00755.1 - 0.0056 16.7 37.3 0.0056 16.7 25.9 8.5 2 1 1 4 4 4 1 Domain of unknown function (DUF1720) Glyco_hydro_47 PF01532.15 CCM00756.1 - 3.7e-104 348.8 0.0 5.6e-104 348.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FGGY_N PF00370.16 CCM00757.1 - 1.2e-63 214.7 0.2 5e-62 209.4 0.2 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CCM00757.1 - 7.7e-61 205.1 1.5 1.6e-60 204.1 0.9 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Pkinase PF00069.20 CCM00758.1 - 2.8e-34 118.4 0.0 4.5e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00758.1 - 3.4e-12 45.9 0.0 5.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM00758.1 - 2.3e-06 27.5 0.5 0.0017 18.1 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCM00758.1 - 0.028 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.24 CCM00759.1 - 5.3e-38 130.1 0.6 7.9e-38 129.6 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM00759.1 - 3.1e-21 75.0 0.2 2.1e-12 46.7 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CCM00759.1 - 3.1e-05 23.9 0.2 0.00029 20.7 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 CCM00759.1 - 0.0036 15.4 1.3 0.0056 14.7 0.9 1.2 1 0 0 1 1 1 1 CDC45-like protein Apt1 PF10351.4 CCM00759.1 - 3.8 6.2 9.1 6.4 5.5 6.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain F-box-like PF12937.2 CCM00761.1 - 2.9e-13 49.2 3.9 4.6e-11 42.2 0.0 3.7 4 0 0 4 4 4 2 F-box-like F-box PF00646.28 CCM00761.1 - 0.00092 18.8 0.5 0.15 11.7 0.0 3.4 3 0 0 3 3 3 2 F-box domain Catalase PF00199.14 CCM00762.1 - 3.9e-164 545.8 0.1 5.2e-164 545.4 0.1 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCM00762.1 - 9e-19 67.1 0.1 2.2e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 CCM00762.1 - 8.7e-13 47.9 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CCM00762.1 - 6.2e-05 22.3 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S41 PF03572.13 CCM00765.1 - 0.00026 20.4 0.0 0.00046 19.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Aldo_ket_red PF00248.16 CCM00766.1 - 3.1e-49 167.3 0.0 4.6e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 CCM00767.1 - 1.3e-32 112.6 0.0 2.1e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 CCM00767.1 - 1.4e-29 102.7 0.0 2.3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 CCM00767.1 - 3.5e-11 42.9 0.0 6.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CCM00767.1 - 0.0008 19.6 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site BTB PF00651.26 CCM00768.1 - 0.0008 19.3 0.0 0.0028 17.6 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF605 PF04652.11 CCM00769.1 - 2.1 7.6 10.2 2.8 7.2 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Sod_Fe_C PF02777.13 CCM00771.1 - 1.2e-35 121.5 0.1 2e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCM00771.1 - 5.3e-32 109.9 3.2 7.9e-32 109.3 0.9 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 CCM00771.1 - 0.27 11.1 2.0 0.9 9.4 1.1 1.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain NAD_binding_4 PF07993.7 CCM00772.1 - 5.2e-36 123.8 0.0 6.6e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CCM00772.1 - 1.4e-11 44.2 0.0 2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM00772.1 - 0.00028 19.7 0.0 0.00047 18.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TOMM6 PF15184.1 CCM00772.1 - 0.0018 17.5 0.0 0.0088 15.3 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial import receptor subunit TOM6 homolog adh_short PF00106.20 CCM00772.1 - 0.0038 17.1 1.5 0.017 15.0 0.8 2.4 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CCM00772.1 - 0.057 12.3 0.2 1.5 7.6 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CCM00772.1 - 0.069 12.0 0.0 0.61 8.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 CCM00772.1 - 0.19 11.3 2.0 0.19 11.3 0.3 1.9 2 1 0 2 2 2 0 KR domain ABC_membrane_2 PF06472.10 CCM00773.1 - 7.4e-82 274.6 0.6 1.1e-81 274.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCM00773.1 - 3.2e-16 59.8 0.0 1.2e-15 58.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 CCM00773.1 - 0.015 14.6 0.1 0.077 12.3 0.2 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CCM00773.1 - 0.062 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 CCM00773.1 - 0.063 13.0 1.1 0.33 10.7 0.3 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 CCM00773.1 - 0.066 13.2 0.1 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CCM00773.1 - 0.11 12.6 0.1 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CCM00773.1 - 0.16 11.4 0.2 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain SMC_N PF02463.14 CCM00773.1 - 0.28 10.4 0.0 2.2 7.4 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF4017 PF13209.1 CCM00774.1 - 0.03 14.1 1.1 0.095 12.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) Kinetochor_Ybp2 PF08568.5 CCM00775.1 - 5.3e-17 61.3 0.1 6.2e-13 47.8 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin SNF2_N PF00176.18 CCM00776.1 - 4e-64 216.2 2.8 7.2e-64 215.4 2.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM00776.1 - 5.1e-10 39.0 0.0 1.7e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CCM00776.1 - 2e-09 37.0 7.4 4.1e-09 36.1 5.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCM00776.1 - 1.7e-08 34.3 7.7 3.6e-08 33.2 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCM00776.1 - 7.6e-08 31.9 6.7 1.4e-07 31.0 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CCM00776.1 - 9.7e-08 32.0 0.0 2.9e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 CCM00776.1 - 2.2e-07 30.4 1.1 5e-07 29.3 0.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CCM00776.1 - 6e-06 25.8 8.1 1.3e-05 24.7 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM00776.1 - 6.3e-06 25.8 7.7 1.2e-05 24.8 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCM00776.1 - 2.6e-05 23.9 7.2 7.4e-05 22.5 5.0 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 CCM00776.1 - 0.097 12.2 3.1 0.23 11.0 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 CCM00776.1 - 0.17 12.0 3.4 0.57 10.3 2.4 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 CCM00776.1 - 0.19 11.6 7.7 0.45 10.4 5.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger DUF3123 PF11321.3 CCM00776.1 - 0.34 11.2 5.8 2.2 8.5 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3123) Dicty_CAR PF05462.6 CCM00777.1 - 3.6e-06 26.0 4.9 5e-06 25.6 3.4 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 CCM00777.1 - 0.0018 17.3 10.0 0.0067 15.5 3.8 2.0 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) YfhO PF09586.5 CCM00777.1 - 1.7 6.5 4.6 2.8 5.8 2.5 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO TPPK_C PF12555.3 CCM00778.1 - 0.12 12.1 4.5 0.48 10.1 0.5 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal FMN_dh PF01070.13 CCM00779.1 - 3.6e-106 355.0 0.0 4.8e-106 354.5 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCM00779.1 - 4.6e-18 64.7 0.0 1e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CCM00779.1 - 0.0013 17.6 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CCM00779.1 - 0.0029 16.8 0.0 0.041 13.0 0.1 2.1 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.20 CCM00779.1 - 0.006 15.5 0.4 0.043 12.7 0.1 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 CCM00779.1 - 0.074 12.3 0.0 7.3 5.7 0.0 2.5 3 0 0 3 3 3 0 Histidine biosynthesis protein RdRP PF05183.7 CCM00780.1 - 1.9e-128 429.6 0.0 2.7e-128 429.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase G-alpha PF00503.15 CCM00780.1 - 2.1e-103 346.0 0.0 6.8e-66 222.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 CCM00780.1 - 0.019 14.2 0.3 1.2 8.3 0.0 3.1 2 1 1 3 3 3 0 ADP-ribosylation factor family AAA_29 PF13555.1 CCM00780.1 - 0.022 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain adh_short PF00106.20 CCM00781.1 - 5.1e-16 59.0 0.3 8.3e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM00781.1 - 2.9e-11 43.5 0.0 3.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM00781.1 - 1.2e-05 25.0 1.0 2.5e-05 24.0 0.7 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 CCM00781.1 - 1.3e-05 24.5 0.8 2.5e-05 23.6 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CCM00781.1 - 1.6e-05 24.9 0.3 3.4e-05 23.9 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM00781.1 - 6.3e-05 22.5 0.1 0.0001 21.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 CCM00781.1 - 0.0008 19.3 0.2 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 CCM00781.1 - 0.022 13.4 0.1 0.03 13.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CCM00781.1 - 0.029 13.2 0.2 0.065 12.1 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Mob1_phocein PF03637.12 CCM00782.1 - 3.2e-26 92.0 0.1 7.5e-26 90.8 0.0 1.5 2 0 0 2 2 2 1 Mob1/phocein family ABC2_membrane PF01061.19 CCM00783.1 - 1.1e-75 253.3 51.0 2.7e-42 144.2 13.0 3.0 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CCM00783.1 - 2.5e-38 129.8 10.6 5.4e-31 106.3 0.0 2.9 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 CCM00783.1 - 2e-37 128.5 0.0 1.5e-17 64.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 CCM00783.1 - 1.8e-16 59.9 0.0 4.2e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 CCM00783.1 - 1.1e-06 27.8 0.0 0.00013 21.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCM00783.1 - 4.5e-06 26.2 0.0 0.012 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCM00783.1 - 9.8e-06 25.6 0.0 0.2 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CCM00783.1 - 3.7e-05 23.8 0.0 0.41 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 CCM00783.1 - 0.00013 21.4 0.0 0.17 11.3 0.1 2.8 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCM00783.1 - 0.00027 21.2 0.0 0.16 12.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCM00783.1 - 0.00048 19.5 0.4 0.052 13.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 CCM00783.1 - 0.00095 19.0 0.1 0.82 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCM00783.1 - 0.0033 18.2 0.0 0.72 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CCM00783.1 - 0.0045 16.9 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 CCM00783.1 - 0.005 16.8 0.5 2.6 7.9 0.4 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCM00783.1 - 0.015 14.9 0.1 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CCM00783.1 - 0.025 14.2 0.3 1.6 8.3 0.2 2.5 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 CCM00783.1 - 0.028 14.8 0.0 14 6.2 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein SbcCD_C PF13558.1 CCM00783.1 - 0.033 14.0 0.0 1.2 9.0 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 CCM00783.1 - 0.035 13.8 0.7 3.3 7.5 0.3 2.8 2 0 0 2 2 2 0 Part of AAA domain SMC_N PF02463.14 CCM00783.1 - 0.047 12.9 0.0 1.1 8.4 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 CCM00783.1 - 0.06 12.4 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 CCM00783.1 - 0.063 12.7 0.1 6.2 6.1 0.3 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 CCM00783.1 - 0.064 13.2 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCM00783.1 - 0.072 12.5 0.0 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC2_membrane_3 PF12698.2 CCM00783.1 - 0.13 11.2 53.0 0.31 10.0 18.5 3.0 2 2 0 2 2 2 0 ABC-2 family transporter protein PduV-EutP PF10662.4 CCM00783.1 - 0.14 11.6 0.4 0.99 8.8 0.2 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CCM00783.1 - 0.18 10.8 0.0 6.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 CCM00783.1 - 0.26 11.6 0.0 0.49 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCM00783.1 - 0.26 10.9 0.0 30 4.2 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Calcipressin PF04847.7 CCM00786.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Calcipressin Transglut_core PF01841.14 CCM00790.1 - 1.1e-11 44.9 0.0 2.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 CCM00790.1 - 0.0006 19.1 0.0 0.0039 16.4 0.0 2.0 1 1 0 1 1 1 1 Transglutaminase-like domain Hce2 PF14856.1 CCM00794.1 - 0.0071 16.2 0.1 0.035 13.9 0.0 1.9 1 1 1 2 2 2 1 Pathogen effector; putative necrosis-inducing factor Pkinase PF00069.20 CCM00795.1 - 1.6e-05 24.2 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCM00795.1 - 0.00088 19.0 0.6 0.0035 17.1 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family IL34 PF15036.1 CCM00795.1 - 0.12 11.9 0.0 7.5 6.0 0.0 2.2 1 1 0 2 2 2 0 Interleukin 34 SDA1 PF05285.7 CCM00795.1 - 2.4 7.3 21.4 0.058 12.6 10.5 1.4 2 0 0 2 2 2 0 SDA1 CobT PF06213.7 CCM00795.1 - 2.7 7.0 16.2 4.1 6.4 11.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CH PF00307.26 CCM00796.1 - 1.8e-70 233.8 0.0 3.2e-20 72.1 0.1 4.8 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CCM00796.1 - 8.6e-08 31.7 0.0 1.2 8.8 0.0 4.5 4 0 0 4 4 4 4 CAMSAP CH domain Amidase PF01425.16 CCM00797.1 - 1.2e-88 297.8 0.0 1.5e-88 297.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.16 CCM00798.1 - 2.5e-86 290.2 0.0 3e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Baculo_PEP_C PF04513.7 CCM00799.1 - 0.00022 21.0 3.2 0.15 11.8 0.1 3.1 3 1 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Ax_dynein_light PF10211.4 CCM00799.1 - 0.042 13.6 1.1 0.4 10.5 0.0 2.7 3 0 0 3 3 3 0 Axonemal dynein light chain Apolipoprotein PF01442.13 CCM00799.1 - 0.052 13.0 0.1 0.42 10.0 0.0 2.4 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain IMD PF08397.6 CCM00799.1 - 0.083 12.1 0.1 16 4.7 0.0 3.1 3 0 0 3 3 3 0 IRSp53/MIM homology domain PEP-utilisers_N PF05524.8 CCM00799.1 - 0.14 11.9 1.3 1 9.1 0.4 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal WXG100 PF06013.7 CCM00799.1 - 1.8 8.6 8.7 16 5.5 0.3 4.0 3 3 0 3 3 3 0 Proteins of 100 residues with WXG Prefoldin PF02996.12 CCM00799.1 - 4.3 7.0 9.4 0.49 10.0 0.7 2.9 3 0 0 3 3 3 0 Prefoldin subunit DivIC PF04977.10 CCM00799.1 - 4.7 6.7 6.4 6 6.4 0.2 2.9 3 0 0 3 3 3 0 Septum formation initiator Seryl_tRNA_N PF02403.17 CCM00800.1 - 0.008 16.1 5.0 2.4 8.2 0.1 3.3 2 1 1 3 3 3 2 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 CCM00800.1 - 0.021 14.0 2.2 0.13 11.4 0.9 2.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Lzipper-MIP1 PF14389.1 CCM00800.1 - 0.033 14.2 0.0 0.24 11.5 0.0 2.3 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Bacillus_HBL PF05791.6 CCM00800.1 - 0.041 13.2 5.3 0.033 13.5 1.2 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF904 PF06005.7 CCM00800.1 - 0.13 12.5 3.0 0.53 10.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 CCM00800.1 - 0.2 11.1 5.6 3.4 7.2 0.3 2.9 3 0 0 3 3 3 0 Septum formation initiator DUF2968 PF11180.3 CCM00800.1 - 0.21 10.9 2.0 0.5 9.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Baculo_PEP_C PF04513.7 CCM00800.1 - 0.23 11.2 3.4 1.1 9.0 0.4 2.9 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mod_r PF07200.8 CCM00800.1 - 0.25 11.2 5.3 0.66 9.8 0.2 3.1 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Lectin_N PF03954.9 CCM00800.1 - 0.71 9.2 5.4 0.88 8.9 0.5 2.7 2 1 0 3 3 3 0 Hepatic lectin, N-terminal domain LPP PF04728.8 CCM00801.1 - 0.057 13.2 1.2 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Rotamase_2 PF13145.1 CCM00801.1 - 0.3 11.7 3.8 7.3 7.2 2.6 2.2 1 1 0 1 1 1 0 PPIC-type PPIASE domain Pkinase PF00069.20 CCM00802.1 - 1.6e-39 135.6 0.0 1.9e-27 96.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00802.1 - 4e-22 78.5 0.0 5.5e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM00802.1 - 0.0053 16.5 0.6 0.0053 16.5 0.4 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 CCM00805.1 - 2.9e-56 190.5 0.0 4.1e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00805.1 - 2.3e-27 95.7 0.0 4e-27 94.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCM00805.1 - 0.00021 21.1 0.3 0.0067 16.1 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CCM00805.1 - 0.00084 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CCM00805.1 - 0.026 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CCM00805.1 - 0.049 12.5 0.0 0.14 11.0 0.0 1.8 1 1 1 2 2 2 0 Kinase-like Pkinase PF00069.20 CCM00806.1 - 1.1e-53 182.0 0.0 1.6e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00806.1 - 1.5e-29 102.8 0.0 2e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM00806.1 - 1.1e-05 24.5 0.0 2.3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCM00806.1 - 0.0029 17.4 0.0 0.016 14.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CCM00806.1 - 0.0069 15.2 0.1 0.0098 14.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 CCM00806.1 - 0.053 12.8 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 CCM00806.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family TEP1_N PF05386.6 CCM00806.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 TEP1 N-terminal domain SET PF00856.23 CCM00807.1 - 2.3e-08 34.5 0.0 3.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 SET domain KTI12 PF08433.5 CCM00807.1 - 0.14 11.2 0.1 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FA_desaturase PF00487.19 CCM00809.1 - 1.7e-22 80.0 22.0 3.1e-22 79.2 15.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CCM00809.1 - 1.7e-08 34.5 0.1 3.6e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Alpha-L-AF_C PF06964.7 CCM00811.1 - 2.8e-44 151.0 0.5 3.7e-44 150.6 0.4 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 CCM00812.1 - 7.8e-103 344.4 32.7 8.9e-103 344.2 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM00812.1 - 7.1e-18 64.4 51.6 2.1e-16 59.6 12.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Lactamase_B_2 PF12706.2 CCM00813.1 - 3.4e-29 101.7 0.0 7.6e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCM00813.1 - 2.4e-05 24.0 0.0 0.00012 21.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Kelch_6 PF13964.1 CCM00814.1 - 0.0083 16.2 0.1 0.24 11.6 0.1 3.0 2 0 0 2 2 2 1 Kelch motif Abhydrolase_1 PF00561.15 CCM00815.1 - 4.2e-07 29.7 0.1 1.9e-06 27.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 CCM00815.1 - 9.1e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein p450 PF00067.17 CCM00817.1 - 4.9e-50 170.4 0.0 5.7e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4_2 PF13923.1 CCM00819.1 - 3.5e-10 39.7 21.1 2.7e-05 24.0 1.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CCM00819.1 - 2e-09 37.0 11.4 4.5e-07 29.3 0.3 2.9 2 1 0 2 2 2 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 CCM00819.1 - 4.2e-08 32.7 18.3 6.6e-05 22.5 5.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCM00819.1 - 4.3e-06 26.4 18.2 0.0087 15.8 1.0 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 CCM00819.1 - 2.6e-05 23.8 21.3 8.7e-05 22.1 6.8 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 CCM00819.1 - 5.3e-05 22.7 22.3 0.022 14.3 8.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 CCM00819.1 - 0.00068 19.4 3.3 0.00068 19.4 2.3 2.8 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 CCM00819.1 - 0.0048 16.7 17.4 0.091 12.6 0.9 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCM00819.1 - 0.14 11.8 18.3 0.24 11.1 6.9 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 CCM00819.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CCM00819.1 - 4.4 6.9 15.1 0.2 11.2 3.4 3.1 2 2 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 CCM00819.1 - 8.2 6.3 17.6 6.6 6.6 1.4 3.6 3 1 1 4 4 3 0 Double zinc ribbon Vps39_2 PF10367.4 CCM00819.1 - 9.2 6.4 16.2 0.56 10.4 3.3 3.2 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 zinc-ribbons_6 PF07191.7 CCM00819.1 - 9.4 6.1 16.1 2.5 7.9 4.8 2.6 2 0 0 2 2 2 0 zinc-ribbons Amidase PF01425.16 CCM00820.1 - 1.9e-76 257.7 0.0 1.6e-75 254.6 0.0 2.0 1 1 0 1 1 1 1 Amidase ADH_N PF08240.7 CCM00820.1 - 1.6e-20 72.9 0.2 3.1e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM00820.1 - 6.3e-16 58.1 0.0 1.5e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PARP PF00644.15 CCM00821.1 - 5.1e-06 26.0 0.0 6.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain EIID-AGA PF03613.9 CCM00822.1 - 0.049 12.5 0.2 0.077 11.9 0.1 1.2 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component MACPF PF01823.14 CCM00822.1 - 0.055 13.1 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 MAC/Perforin domain F-box-like PF12937.2 CCM00823.1 - 0.0021 17.7 2.1 0.014 15.0 0.2 3.0 3 0 0 3 3 3 1 F-box-like DUF302 PF03625.9 CCM00825.1 - 7.8e-06 25.3 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF302 F-box-like PF12937.2 CCM00826.1 - 0.0017 18.0 2.0 0.0021 17.7 0.3 2.1 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 CCM00826.1 - 0.73 9.6 7.0 2.1 8.1 0.1 3.3 3 1 0 3 3 3 0 Leucine rich repeat PGM_PMM_I PF02878.11 CCM00827.1 - 5.9e-32 110.0 0.2 9.8e-32 109.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CCM00827.1 - 2.8e-24 85.3 0.0 7.3e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CCM00827.1 - 2.7e-13 50.1 0.0 8.1e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCM00827.1 - 2e-06 27.6 0.0 5.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DIOX_N PF14226.1 CCM00828.1 - 2e-14 54.0 0.0 5.6e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM00828.1 - 2.8e-13 49.9 0.1 1e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Spt5-NGN PF03439.8 CCM00829.1 - 4.5e-23 80.7 0.0 9.5e-23 79.7 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CCM00829.1 - 3.8e-16 58.0 15.6 7.1e-05 22.3 0.0 7.8 8 0 0 8 8 8 5 KOW motif Spt5_N PF11942.3 CCM00829.1 - 3.3e-12 46.8 16.1 3.3e-12 46.8 11.2 3.4 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 CCM00829.1 - 1.3e-06 28.8 42.7 1.1e-05 25.8 21.3 2.6 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 YajC PF02699.10 CCM00829.1 - 0.011 15.3 1.5 0.067 12.8 0.1 2.6 2 1 0 2 2 2 0 Preprotein translocase subunit TFIIF_alpha PF05793.7 CCM00829.1 - 6.3 5.0 33.5 9.2 4.4 23.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 CCM00829.1 - 6.9 5.8 29.0 11 5.2 20.1 1.2 1 0 0 1 1 1 0 SDA1 SPT6_acidic PF14632.1 CCM00829.1 - 9.3 6.4 52.6 3.4 7.8 13.0 2.5 1 1 1 2 2 2 0 Acidic N-terminal SPT6 MFS_1 PF07690.11 CCM00830.1 - 1.5e-33 115.9 48.7 4.7e-33 114.3 33.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CCM00830.1 - 2.2e-13 49.3 14.2 2.2e-13 49.3 9.8 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCM00830.1 - 2.4e-12 46.1 14.4 2.4e-12 46.1 10.0 2.8 1 1 1 3 3 3 1 Sugar (and other) transporter LSM PF01423.17 CCM00833.1 - 2.7e-12 46.0 0.2 4.8e-12 45.2 0.2 1.3 1 0 0 1 1 1 1 LSM domain DASH_Spc34 PF08657.5 CCM00833.1 - 1.6e-05 24.7 3.0 0.00032 20.4 0.0 2.5 1 1 0 2 2 2 1 DASH complex subunit Spc34 Syntaxin PF00804.20 CCM00833.1 - 0.93 9.6 6.6 0.4 10.8 2.3 2.1 2 1 0 2 2 2 0 Syntaxin Pro-kuma_activ PF09286.6 CCM00835.1 - 1.8e-36 125.3 0.0 3.6e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain RhoGAP PF00620.22 CCM00835.1 - 1.9e-28 99.0 0.0 3.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 CCM00835.1 - 3.5e-25 88.1 0.0 8.1e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.21 CCM00835.1 - 4.4e-10 39.2 6.1 2.6e-07 30.3 2.3 2.7 2 0 0 2 2 2 2 WW domain Aldedh PF00171.17 CCM00836.1 - 7.4e-120 400.3 5.0 8.6e-120 400.1 3.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCM00836.1 - 0.00015 20.6 0.6 0.00022 20.0 0.0 1.4 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) ComA PF02679.10 CCM00837.1 - 9.6e-71 237.6 0.0 1.1e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Pro-kuma_activ PF09286.6 CCM00838.1 - 1.3e-31 109.5 0.1 5e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM00838.1 - 4.4e-11 42.4 3.5 4.5e-10 39.1 1.8 2.1 2 0 0 2 2 2 1 Subtilase family tRNA-synt_2 PF00152.15 CCM00839.1 - 3e-74 249.8 0.1 4.4e-74 249.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 CCM00839.1 - 9.3e-19 67.3 0.0 1.3e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 CCM00839.1 - 0.0072 15.5 0.2 2 7.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pro-kuma_activ PF09286.6 CCM00840.1 - 8.7e-33 113.3 0.2 1.7e-32 112.4 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM00840.1 - 1.4e-07 31.0 0.7 2.2e-07 30.3 0.5 1.3 1 0 0 1 1 1 1 Subtilase family DUF1932 PF09130.6 CCM00841.1 - 1.3e-14 53.6 0.0 3.3e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 CCM00841.1 - 1.5e-07 31.3 0.0 2.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 CCM00841.1 - 1.8e-05 23.9 0.0 2.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CCM00841.1 - 2e-05 24.9 0.3 0.00013 22.2 0.1 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 CCM00841.1 - 0.0011 18.6 0.3 0.0027 17.3 0.2 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 CCM00841.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain DFP PF04127.10 CCM00841.1 - 0.068 12.7 0.7 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Rossmann-like PF10727.4 CCM00841.1 - 0.1 12.3 0.3 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Rossmann-like domain G-alpha PF00503.15 CCM00842.1 - 5.3e-119 397.3 0.0 7.6e-119 396.8 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCM00842.1 - 1.1e-10 41.0 0.1 4e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM00842.1 - 0.0085 15.5 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CCM00842.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCM00842.1 - 0.029 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ribosomal_L18ae PF01775.12 CCM00842.1 - 0.087 12.7 0.8 0.2 11.5 0.2 1.8 2 0 0 2 2 2 0 Ribosomal L18ae/LX protein domain Form_Nir_trans PF01226.12 CCM00843.1 - 1.2e-68 230.7 14.7 2.7e-43 147.6 4.4 2.0 1 1 1 2 2 2 2 Formate/nitrite transporter DSPc PF00782.15 CCM00844.1 - 1.9e-28 98.7 0.0 2.5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCM00844.1 - 0.014 14.7 0.1 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DHDPS PF00701.17 CCM00845.1 - 7e-29 100.3 0.0 2.6e-28 98.4 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family HET PF06985.6 CCM00849.1 - 2.1e-36 125.1 0.0 3.9e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABA_GPCR PF12430.3 CCM00850.1 - 6.6e-37 126.5 0.0 6.6e-37 126.5 0.0 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CCM00850.1 - 8.1e-11 41.8 0.1 2.6e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) Spore_permease PF03845.8 CCM00850.1 - 0.0097 14.5 0.5 0.0097 14.5 0.3 1.8 2 0 0 2 2 2 1 Spore germination protein Sugar_tr PF00083.19 CCM00851.1 - 5.3e-85 285.6 20.7 6e-85 285.4 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM00851.1 - 2e-20 72.8 41.5 4.6e-13 48.6 15.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCM00851.1 - 0.0046 15.2 4.5 0.0073 14.5 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ACPS PF01648.15 CCM00852.1 - 0.0015 18.2 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Sugar_tr PF00083.19 CCM00853.1 - 2.2e-73 247.3 18.5 2.1e-66 224.3 7.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCM00853.1 - 1.3e-14 53.6 22.8 2.4e-09 36.4 6.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily DUF1228 PF06779.9 CCM00853.1 - 0.21 11.6 5.2 1.3 9.1 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) ABC2_membrane_5 PF13346.1 CCM00853.1 - 0.48 9.6 0.0 0.48 9.6 0.0 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein F-box-like PF12937.2 CCM00855.1 - 0.00015 21.4 0.0 0.00043 19.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like Phage_AlpA PF05930.7 CCM00855.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) F-box PF00646.28 CCM00855.1 - 0.06 13.0 0.3 6.9 6.4 0.1 3.1 2 0 0 2 2 2 0 F-box domain TM1506 PF08973.5 CCM00856.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) p450 PF00067.17 CCM00858.1 - 9.6e-85 284.8 0.0 1.1e-84 284.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1191 PF06697.7 CCM00859.1 - 0.03 13.1 0.2 0.21 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) MitoNEET_N PF10660.4 CCM00859.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF3328 PF11807.3 CCM00861.1 - 2.3e-25 89.5 0.3 3.1e-25 89.1 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) GWT1 PF06423.7 CCM00862.1 - 4.1e-27 94.9 0.0 1.3e-26 93.3 0.0 1.8 1 1 0 1 1 1 1 GWT1 TauD PF02668.11 CCM00864.1 - 8.1e-43 146.9 0.1 1e-42 146.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F-box PF00646.28 CCM00865.1 - 0.02 14.5 0.6 0.16 11.6 0.4 2.6 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 CCM00865.1 - 0.026 14.2 0.2 0.071 12.8 0.1 1.8 1 0 0 1 1 1 0 F-box-like FAD_binding_4 PF01565.18 CCM00866.1 - 8.6e-21 73.8 1.7 1.7e-20 72.9 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N PF00107.21 CCM00867.1 - 4.3e-20 71.5 0.0 7.2e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM00867.1 - 7.8e-07 30.0 0.0 2.8e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCM00868.1 - 2.1e-20 72.5 0.0 3.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM00868.1 - 6.2e-05 23.8 0.0 0.00015 22.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase p450 PF00067.17 CCM00869.1 - 1.8e-64 217.9 0.0 2.8e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 CCM00870.1 - 1.1e-30 106.4 0.1 3.4e-21 75.2 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family MFS_1 PF07690.11 CCM00871.1 - 2.4e-38 131.7 30.9 2.4e-38 131.7 21.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.2 CCM00872.1 - 0.019 14.6 0.1 0.051 13.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like FAD_binding_4 PF01565.18 CCM00874.1 - 1.5e-21 76.3 4.6 2.6e-21 75.5 3.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CCM00874.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like p450 PF00067.17 CCM00875.1 - 2.8e-48 164.6 0.1 3.6e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 CCM00876.1 - 0.028 14.1 1.0 0.078 12.7 0.7 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 CCM00879.1 - 0.062 12.9 0.0 0.34 10.6 0.0 2.3 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 CCM00880.1 - 0.0019 17.9 0.1 0.012 15.3 0.1 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 CCM00880.1 - 0.015 14.9 1.2 0.29 10.8 0.3 3.0 2 1 0 2 2 2 0 F-box domain ODV-E18 PF10717.4 CCM00881.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Abhydrolase_6 PF12697.2 CCM00883.1 - 9.5e-18 64.9 1.3 1.1e-11 45.0 0.1 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM00883.1 - 1.8e-07 31.0 0.1 0.0038 16.9 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM00883.1 - 3.4e-05 23.5 0.0 6.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Aa_trans PF01490.13 CCM00885.1 - 2.2e-33 115.3 37.4 2.5e-33 115.1 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2254 PF10011.4 CCM00885.1 - 0.72 8.2 5.1 0.36 9.2 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Acyltransferase PF01553.16 CCM00886.1 - 1.8e-20 72.6 0.0 3.1e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase zf-Tim10_DDP PF02953.10 CCM00887.1 - 6.8e-20 70.1 1.4 8.4e-20 69.8 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AlaDh_PNT_N PF05222.10 CCM00890.1 - 2.5e-21 76.1 0.0 2.8e-20 72.7 0.0 2.1 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CCM00890.1 - 4e-12 46.0 0.0 7.5e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1900 PF08954.6 CCM00890.1 - 0.041 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) Peptidase_M22 PF00814.20 CCM00891.1 - 9.3e-83 277.8 0.0 1.1e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Glyco_transf_8 PF01501.15 CCM00892.1 - 1.5e-30 106.3 0.0 1.9e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CCM00892.1 - 0.00024 20.5 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Radical_SAM PF04055.16 CCM00893.1 - 6.9e-13 49.0 0.0 1.1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily PEX11 PF05648.9 CCM00894.1 - 5.5e-47 159.8 0.3 5.5e-47 159.8 0.2 1.3 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) Thoc2 PF11732.3 CCM00894.1 - 0.068 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Lyase_1 PF00206.15 CCM00895.1 - 2e-119 398.4 0.0 3.2e-119 397.7 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CCM00895.1 - 1.5e-20 73.0 0.0 3.4e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 CCM00895.1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain SNF2_N PF00176.18 CCM00896.1 - 5.6e-73 245.3 1.4 1.1e-72 244.3 1.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 CCM00896.1 - 3.4e-51 172.9 17.0 3.4e-51 172.9 11.8 2.2 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 CCM00896.1 - 8.2e-13 48.0 0.0 2.2e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCM00896.1 - 4.2e-07 29.0 0.0 5.4e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CCM00896.1 - 6.1e-05 22.9 0.0 0.00017 21.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HA2 PF04408.18 CCM00897.1 - 8.6e-17 61.0 0.0 2.5e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCM00897.1 - 1.8e-12 46.9 0.1 4.3e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CCM00897.1 - 1.2e-11 44.4 0.0 3.1e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CCM00897.1 - 6e-07 29.1 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCM00897.1 - 2.6e-06 27.5 0.0 7.9e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCM00897.1 - 0.034 14.4 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CCM00897.1 - 0.076 12.5 0.0 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CCM00897.1 - 0.099 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Ribosomal_L22e PF01776.12 CCM00898.1 - 9.5e-46 154.4 0.3 1.3e-45 154.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family DKCLD PF08068.7 CCM00899.1 - 3.8e-30 103.5 0.1 1.3e-29 101.8 0.1 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CCM00899.1 - 2.7e-21 76.2 0.2 2.8e-18 66.5 0.2 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CCM00899.1 - 6e-17 61.1 0.2 1.1e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 PUA domain Pkinase PF00069.20 CCM00901.1 - 4.8e-61 206.1 0.0 5.6e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00901.1 - 2e-22 79.4 0.0 2.8e-22 79.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM00901.1 - 0.0028 16.6 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCM00901.1 - 0.011 14.8 0.1 0.018 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family S_100 PF01023.14 CCM00901.1 - 0.014 14.6 0.3 0.062 12.6 0.1 2.1 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain APH PF01636.18 CCM00901.1 - 0.017 14.9 0.1 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 CCM00901.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family NPV_P10 PF05531.7 CCM00902.1 - 0.0002 21.5 1.7 0.00054 20.1 1.1 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein IncA PF04156.9 CCM00902.1 - 0.0013 18.4 4.0 0.0021 17.6 2.8 1.3 1 0 0 1 1 1 1 IncA protein FlxA PF14282.1 CCM00902.1 - 0.0018 18.2 9.0 0.012 15.5 6.3 2.3 1 1 0 1 1 1 1 FlxA-like protein CENP-F_leu_zip PF10473.4 CCM00902.1 - 0.0066 16.3 2.2 0.012 15.4 1.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 CCM00902.1 - 0.0089 15.2 0.8 0.014 14.5 0.5 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CCM00902.1 - 0.0096 15.7 3.1 0.036 13.8 2.1 2.1 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DASH_Dam1 PF08653.5 CCM00902.1 - 0.015 15.0 0.9 0.33 10.7 0.1 2.3 1 1 1 2 2 2 0 DASH complex subunit Dam1 Phage_GP20 PF06810.6 CCM00902.1 - 0.027 13.9 1.7 0.056 12.8 1.2 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 ATG16 PF08614.6 CCM00902.1 - 0.033 14.0 4.1 0.068 12.9 2.8 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc42p PF11544.3 CCM00902.1 - 0.038 13.9 0.2 0.15 12.0 0.1 2.0 1 1 0 1 1 1 0 Spindle pole body component Spc42p DUF1192 PF06698.6 CCM00902.1 - 0.038 13.8 2.8 0.7 9.7 0.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) Filament PF00038.16 CCM00902.1 - 0.039 13.4 3.7 0.059 12.8 2.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein TMF_TATA_bd PF12325.3 CCM00902.1 - 0.047 13.4 3.0 0.088 12.5 2.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Dor1 PF04124.7 CCM00902.1 - 0.049 12.0 1.5 0.071 11.5 1.1 1.1 1 0 0 1 1 1 0 Dor1-like family SAP PF02037.22 CCM00902.1 - 0.052 13.0 0.5 0.11 11.9 0.3 1.6 1 0 0 1 1 1 0 SAP domain HALZ PF02183.13 CCM00902.1 - 0.07 12.8 1.4 5.2 6.8 0.0 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper Allexi_40kDa PF05549.6 CCM00902.1 - 0.076 12.3 2.5 0.13 11.5 1.7 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF972 PF06156.8 CCM00902.1 - 0.086 13.1 1.9 0.28 11.5 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 CCM00902.1 - 0.09 12.0 4.2 0.14 11.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TBPIP PF07106.8 CCM00902.1 - 0.095 12.2 2.0 0.2 11.1 1.4 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 CCM00902.1 - 0.11 11.1 3.2 0.16 10.5 2.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Surfac_D-trimer PF09006.6 CCM00902.1 - 0.11 12.2 2.6 3.1 7.6 0.4 2.8 2 1 1 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Fzo_mitofusin PF04799.8 CCM00902.1 - 0.11 11.8 2.0 0.19 11.0 0.7 1.7 1 1 1 2 2 2 0 fzo-like conserved region Baculo_PEP_C PF04513.7 CCM00902.1 - 0.12 12.1 6.2 0.18 11.6 3.2 1.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3573 PF12097.3 CCM00902.1 - 0.12 10.9 0.2 0.23 10.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) AAA_13 PF13166.1 CCM00902.1 - 0.16 10.4 0.5 0.22 9.9 0.3 1.1 1 0 0 1 1 1 0 AAA domain DUF3373 PF11853.3 CCM00902.1 - 0.19 10.2 0.5 0.29 9.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) FlaC_arch PF05377.6 CCM00902.1 - 0.2 11.6 0.2 0.64 9.9 0.1 1.9 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2968 PF11180.3 CCM00902.1 - 0.25 10.7 5.1 0.43 9.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Reo_sigmaC PF04582.7 CCM00902.1 - 0.31 10.1 3.0 0.48 9.5 2.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 CCM00902.1 - 0.35 10.6 4.3 0.74 9.5 3.0 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.12 CCM00902.1 - 0.4 10.3 3.6 2.7 7.6 0.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.4 CCM00902.1 - 0.47 10.6 2.3 0.99 9.5 0.8 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 CCM00902.1 - 0.55 10.5 3.9 4.5 7.6 2.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 CCM00902.1 - 0.56 9.7 3.7 11 5.5 2.6 2.4 1 1 0 1 1 1 0 Septum formation initiator FUSC PF04632.7 CCM00902.1 - 0.78 8.0 4.7 1.2 7.4 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.1 CCM00902.1 - 0.81 10.1 5.3 1.9 8.9 0.7 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) T2SM PF04612.7 CCM00902.1 - 0.87 9.3 8.3 0.14 11.9 1.1 2.5 2 1 1 3 3 2 0 Type II secretion system (T2SS), protein M Syntaxin PF00804.20 CCM00902.1 - 1.1 9.4 5.3 1.4 9.1 1.3 2.1 1 1 1 2 2 2 0 Syntaxin bZIP_2 PF07716.10 CCM00902.1 - 1.7 8.5 3.7 10 6.0 0.5 2.9 2 1 1 3 3 3 0 Basic region leucine zipper FMN_dh PF01070.13 CCM00903.1 - 3.7e-99 331.9 0.0 4.6e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCM00903.1 - 1e-22 79.6 0.0 2e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ThiG PF05690.9 CCM00903.1 - 0.0023 17.0 0.0 0.19 10.7 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 CCM00903.1 - 0.0027 16.6 0.0 0.053 12.3 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CCM00903.1 - 0.035 13.0 0.0 0.094 11.6 0.0 1.6 1 0 0 1 1 1 0 Conserved region in glutamate synthase FMN_dh PF01070.13 CCM00904.1 - 3.9e-106 354.8 0.0 5.4e-106 354.4 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCM00904.1 - 3.5e-20 71.5 0.0 6.4e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CCM00904.1 - 9.3e-05 21.4 0.7 0.00016 20.6 0.0 1.7 2 1 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 CCM00904.1 - 0.0014 17.5 0.0 0.0031 16.4 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 CCM00904.1 - 0.12 11.4 0.1 4.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Formyl_trans_N PF00551.14 CCM00905.1 - 3.4e-34 117.9 0.0 6.8e-33 113.7 0.0 2.0 1 1 0 1 1 1 1 Formyl transferase DnaJ PF00226.26 CCM00907.1 - 4e-18 64.9 1.9 6.2e-18 64.3 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 CCM00907.1 - 0.028 14.4 1.2 0.05 13.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF4200 PF13863.1 CCM00908.1 - 0.11 12.4 2.7 0.27 11.2 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 CCM00908.1 - 1.4 8.6 5.7 0.39 10.4 1.4 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein LIM PF00412.17 CCM00910.1 - 3.9e-13 49.2 25.6 1.4e-06 28.2 3.8 5.3 5 1 0 5 5 5 3 LIM domain Sin_N PF04801.8 CCM00911.1 - 2.6e-21 75.9 0.2 3.6e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region AAA_18 PF13238.1 CCM00913.1 - 7.3e-27 94.2 0.0 1.3e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCM00913.1 - 1.4e-12 48.4 0.0 2.2e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCM00913.1 - 8.2e-05 22.2 0.5 0.00016 21.3 0.3 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CCM00913.1 - 9e-05 22.3 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CCM00913.1 - 0.00028 21.1 0.0 0.00068 19.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 CCM00913.1 - 0.00069 19.0 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_28 PF13521.1 CCM00913.1 - 0.00069 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 CCM00913.1 - 0.0021 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 CCM00913.1 - 0.0042 16.3 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 CCM00913.1 - 0.0043 17.1 0.0 0.0073 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCM00913.1 - 0.0081 15.2 0.0 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 CCM00913.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ADK PF00406.17 CCM00913.1 - 0.012 15.5 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase SKI PF01202.17 CCM00913.1 - 0.02 14.7 0.0 0.1 12.4 0.0 1.9 1 1 0 1 1 1 0 Shikimate kinase AAA_16 PF13191.1 CCM00913.1 - 0.036 14.0 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 CCM00913.1 - 0.038 12.7 0.1 0.11 11.2 0.0 1.7 2 0 0 2 2 2 0 ArgK protein dNK PF01712.14 CCM00913.1 - 0.043 13.7 0.1 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_30 PF13604.1 CCM00913.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCM00913.1 - 0.05 13.4 0.0 0.24 11.3 0.0 1.9 1 1 0 2 2 2 0 AAA domain KaiC PF06745.8 CCM00913.1 - 0.055 12.5 0.1 0.71 8.9 0.0 2.0 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 CCM00913.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 CCM00913.1 - 0.09 12.4 0.4 0.37 10.4 0.1 1.9 2 0 0 2 2 2 0 NTPase PAPA-1 PF04795.7 CCM00915.1 - 4.2e-15 56.2 4.1 4.2e-15 56.2 2.8 2.3 2 1 0 2 2 2 1 PAPA-1-like conserved region HTH_23 PF13384.1 CCM00915.1 - 0.34 10.6 0.0 0.34 10.6 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain Cyclin_N PF00134.18 CCM00917.1 - 1.6e-08 34.1 0.0 3.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain NnrS PF05940.7 CCM00917.1 - 0.55 9.0 4.5 0.68 8.7 0.3 2.1 1 1 1 2 2 2 0 NnrS protein FAM165 PF14981.1 CCM00917.1 - 1.2 8.6 4.5 3 7.4 3.1 1.6 1 0 0 1 1 1 0 FAM165 family GYF PF02213.11 CCM00918.1 - 1.2e-10 40.8 0.0 2.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 GYF domain zf-C2H2 PF00096.21 CCM00919.1 - 1e-16 60.1 23.1 0.0019 18.4 0.1 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM00919.1 - 1.4e-13 50.0 20.0 0.0013 18.8 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CCM00919.1 - 7.1e-05 22.8 15.7 0.24 11.7 0.1 5.2 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 CCM00919.1 - 0.00017 21.6 4.0 1 9.5 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM00919.1 - 0.012 15.8 3.8 27 5.1 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF1644 PF07800.7 CCM00919.1 - 0.085 12.7 6.2 7.6 6.3 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1644) IBR PF01485.16 CCM00919.1 - 0.18 11.7 3.5 5.6 6.9 0.4 3.4 3 1 0 3 3 3 0 IBR domain zf-C2H2_6 PF13912.1 CCM00919.1 - 0.88 9.5 3.8 24 4.9 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Alginate_lyase PF05426.7 CCM00920.1 - 4.5e-52 177.0 0.6 8.7e-50 169.5 0.2 2.1 2 0 0 2 2 2 2 Alginate lyase Ras PF00071.17 CCM00921.1 - 2.6e-54 182.9 0.0 3.4e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM00921.1 - 1.2e-17 64.4 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM00921.1 - 5e-14 51.9 0.0 1.2e-13 50.7 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCM00921.1 - 1.7e-07 30.5 0.0 2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCM00921.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCM00921.1 - 0.00032 20.6 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CCM00921.1 - 0.05 13.5 0.2 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Arrestin_C PF02752.17 CCM00922.1 - 8.1e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF1764 PF08576.5 CCM00923.1 - 1e-17 64.7 5.1 7.7e-17 61.9 0.6 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) HpaP PF09483.5 CCM00923.1 - 1.5 8.7 13.5 2.1 8.2 9.4 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) ORC6 PF05460.8 CCM00923.1 - 7.4 5.5 10.2 8.6 5.3 7.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3518 PF12031.3 CCM00924.1 - 0.00015 20.6 1.4 0.0034 16.2 0.1 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3518) WD40 PF00400.27 CCM00925.1 - 2.4e-09 36.6 10.7 0.0058 16.4 0.2 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat FAD-oxidase_C PF02913.14 CCM00926.1 - 1.1e-56 191.9 0.0 1.9e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCM00926.1 - 1.4e-33 115.2 0.4 2.8e-33 114.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Myb_DNA-bind_2 PF08914.6 CCM00926.1 - 3.4e-09 36.3 0.9 9.1e-09 34.9 0.6 1.7 1 0 0 1 1 1 1 Rap1 Myb domain EFG_II PF14492.1 CCM00926.1 - 0.035 13.9 1.0 0.38 10.6 0.0 2.8 3 0 0 3 3 3 0 Elongation Factor G, domain II Methyltransf_14 PF08484.6 CCM00926.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain A1_Propeptide PF07966.7 CCM00926.1 - 0.095 12.5 0.3 0.36 10.6 0.2 2.1 1 1 0 1 1 1 0 A1 Propeptide Rap1-DNA-bind PF09197.5 CCM00926.1 - 0.15 12.6 3.5 0.52 10.8 1.1 2.7 2 1 0 2 2 2 0 Rap1, DNA-binding Pkinase PF00069.20 CCM00927.1 - 2.5e-68 230.0 0.0 3e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM00927.1 - 6e-27 94.3 0.0 8e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM00927.1 - 1.5e-06 27.3 0.0 0.00018 20.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CCM00927.1 - 0.0014 18.0 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family DUF4407 PF14362.1 CCM00928.1 - 0.011 14.7 4.0 0.011 14.6 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.16 CCM00928.1 - 0.025 14.5 1.6 0.025 14.5 1.1 2.0 2 0 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.7 CCM00928.1 - 0.058 13.5 8.5 0.033 14.3 4.1 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) LRS4 PF10422.4 CCM00928.1 - 0.059 12.7 6.3 0.067 12.5 4.3 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Shugoshin_N PF07558.6 CCM00928.1 - 0.096 12.4 2.5 0.17 11.6 1.7 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 CCM00928.1 - 0.13 12.5 7.0 0.35 11.2 4.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) YlqD PF11068.3 CCM00928.1 - 0.18 11.8 4.5 0.23 11.5 3.1 1.2 1 0 0 1 1 1 0 YlqD protein DASH_Spc19 PF08287.6 CCM00928.1 - 0.22 11.1 6.3 0.25 10.9 4.4 1.2 1 0 0 1 1 1 0 Spc19 Atg14 PF10186.4 CCM00928.1 - 0.23 10.3 4.7 0.26 10.2 3.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MIF4G PF02854.14 CCM00928.1 - 0.24 10.8 2.4 0.32 10.3 1.7 1.3 1 1 0 1 1 1 0 MIF4G domain Tropomyosin_1 PF12718.2 CCM00928.1 - 0.41 10.4 10.9 1.3 8.8 7.6 1.6 1 1 0 1 1 1 0 Tropomyosin like DUF2681 PF10883.3 CCM00928.1 - 0.49 10.6 4.4 0.4 10.9 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Adeno_PIX PF03955.9 CCM00928.1 - 0.61 10.6 3.6 0.83 10.2 0.4 2.0 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Lge1 PF11488.3 CCM00928.1 - 1.5 9.0 4.7 0.41 10.8 1.0 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DivIC PF04977.10 CCM00928.1 - 2 7.9 6.3 0.56 9.7 1.4 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.7 CCM00928.1 - 2.7 7.8 5.3 7.9 6.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.10 CCM00928.1 - 2.8 7.8 8.7 0.31 10.8 3.0 1.7 2 0 0 2 2 2 0 Basic region leucine zipper ADIP PF11559.3 CCM00928.1 - 5.9 6.7 12.1 0.82 9.5 3.0 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Kinetocho_Slk19 PF12709.2 CCM00928.1 - 6.3 6.9 8.5 1.4 9.0 2.4 2.2 2 1 0 2 2 2 0 Central kinetochore-associated IncA PF04156.9 CCM00928.1 - 6.3 6.3 10.9 9.4 5.7 7.6 1.3 1 1 0 1 1 1 0 IncA protein DUF2404 PF10296.4 CCM00929.1 - 3.9e-08 33.3 0.0 7.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) TTL PF03133.10 CCM00930.1 - 9.3e-45 152.7 0.0 3.2e-30 105.0 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family RNA_pol_Rpb8 PF03870.10 CCM00930.1 - 7.2e-30 103.9 0.2 3.2e-29 101.8 0.2 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb8 ATP-grasp_4 PF13535.1 CCM00930.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Con-6 PF10346.4 CCM00931.1 - 5.7e-26 89.6 7.2 9.8e-13 47.2 1.1 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 CCM00931.1 - 0.0077 15.7 3.2 0.014 14.8 0.4 1.9 2 0 0 2 2 2 1 SpoIIIAH-like protein NiFeSe_Hases PF00374.14 CCM00931.1 - 0.1 11.3 0.2 0.1 11.3 0.1 1.0 1 0 0 1 1 1 0 Nickel-dependent hydrogenase ATP-synt_DE PF00401.15 CCM00931.1 - 0.2 11.5 1.6 0.46 10.4 1.1 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Con-6 PF10346.4 CCM00932.1 - 2.8e-25 87.4 6.6 1.3e-12 46.8 0.4 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 CCM00932.1 - 0.004 16.6 4.0 0.0058 16.1 0.2 2.0 1 1 1 2 2 2 1 SpoIIIAH-like protein Toxin_52 PF15605.1 CCM00932.1 - 0.028 14.3 0.5 0.11 12.4 0.1 1.8 1 1 1 2 2 2 0 Putative toxin 52 NAGidase PF07555.8 CCM00932.1 - 0.054 12.4 1.1 0.11 11.3 0.7 1.6 1 1 0 1 1 1 0 beta-N-acetylglucosaminidase RR_TM4-6 PF06459.7 CCM00932.1 - 0.17 11.7 4.0 0.18 11.6 2.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3359 PF11839.3 CCM00932.1 - 0.25 11.6 4.5 0.33 11.3 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) ATP-synt_DE PF00401.15 CCM00932.1 - 1.3 8.9 5.1 1.3 8.9 2.1 1.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Dsh_C PF12316.3 CCM00932.1 - 2.8 7.9 8.2 3.3 7.7 5.7 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Sec7 PF01369.15 CCM00934.1 - 2.8e-40 138.0 0.0 4.7e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CCM00934.1 - 2.3e-13 50.3 0.0 4.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CCM00934.1 - 1.8e-08 34.5 0.1 6e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 PH domain Pescadillo_N PF06732.6 CCM00936.1 - 3.1e-115 384.2 0.0 3.1e-115 384.2 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 CCM00936.1 - 7e-09 35.7 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LSM PF01423.17 CCM00937.1 - 2.8e-08 33.1 0.4 1.6e-07 30.7 0.3 1.9 1 1 0 1 1 1 1 LSM domain F1F0-ATPsyn_F PF10791.4 CCM00937.1 - 0.041 14.1 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi RdRP PF05183.7 CCM00938.1 - 4.8e-159 530.7 0.0 7.3e-159 530.1 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 CCM00938.1 - 0.0094 15.9 0.0 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Caudo_TAP PF02413.12 CCM00938.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Cyclin_N PF00134.18 CCM00940.1 - 1.6e-37 127.9 0.4 3e-37 127.0 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCM00940.1 - 2e-09 37.3 0.2 4.4e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain GFO_IDH_MocA PF01408.17 CCM00941.1 - 2.1e-12 47.5 0.7 8.4e-12 45.6 0.5 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 CCM00941.1 - 0.0089 15.0 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase GFO_IDH_MocA_C PF02894.12 CCM00941.1 - 0.013 15.2 0.2 0.12 12.1 0.2 2.3 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain HrpF PF06266.7 CCM00941.1 - 0.026 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 HrpF protein NAD_binding_3 PF03447.11 CCM00941.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain WAC_Acf1_DNA_bd PF10537.4 CCM00943.1 - 1.2e-31 108.9 0.1 4.7e-31 106.9 0.1 2.0 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CCM00943.1 - 3.6e-14 52.2 0.1 9.6e-14 50.9 0.1 1.7 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.1 CCM00943.1 - 8.6e-05 22.2 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 CCM00943.1 - 0.00012 21.8 0.4 0.00056 19.7 0.1 2.4 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 CCM00943.1 - 0.0017 18.0 0.2 0.0017 18.0 0.1 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 Nop53 PF07767.6 CCM00943.1 - 9.2 5.1 35.8 0.62 9.0 6.1 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Aa_trans PF01490.13 CCM00944.1 - 9.9e-48 162.6 19.4 1.8e-47 161.7 13.5 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PCI_Csn8 PF10075.4 CCM00945.1 - 1e-22 80.4 0.0 1.4e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CCM00945.1 - 1.1e-21 77.3 0.0 1.5e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family WD40 PF00400.27 CCM00946.1 - 2.7e-70 229.9 15.4 7.5e-14 50.9 0.1 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CCM00946.1 - 2.6e-11 43.6 0.2 3.4e-06 26.9 0.0 3.1 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCM00946.1 - 7.8e-07 27.6 6.3 0.18 9.8 0.1 4.8 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCM00946.1 - 9.7e-05 21.2 2.8 0.11 11.2 0.1 3.6 1 1 3 4 4 4 2 Nup133 N terminal like RicinB_lectin_2 PF14200.1 CCM00946.1 - 0.0014 19.0 0.0 1.1 9.7 0.0 2.9 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like IKI3 PF04762.7 CCM00946.1 - 0.0018 16.2 0.0 0.0093 13.8 0.0 1.9 1 1 0 1 1 1 1 IKI3 family FlgD_ig PF13860.1 CCM00946.1 - 0.02 14.6 0.6 0.93 9.2 0.0 2.9 3 0 0 3 3 3 0 FlgD Ig-like domain DUF1513 PF07433.6 CCM00946.1 - 0.02 13.7 0.0 1.3 7.8 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) CDtoxinA PF03498.9 CCM00946.1 - 0.046 13.0 0.1 0.23 10.8 0.0 2.0 1 1 1 2 2 2 0 Cytolethal distending toxin A/C family Coatomer_WDAD PF04053.9 CCM00946.1 - 0.046 12.5 0.1 0.32 9.7 0.0 2.2 2 1 1 3 3 3 0 Coatomer WD associated region ubiquitin PF00240.18 CCM00947.1 - 2.4e-171 555.4 28.5 7.6e-34 114.9 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 CCM00947.1 - 1.4e-96 316.2 28.1 8.4e-19 67.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCM00947.1 - 8.7e-30 102.8 13.7 0.00025 21.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCM00947.1 - 3.3e-26 91.9 1.5 0.002 17.8 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCM00947.1 - 5.1e-17 61.7 5.3 0.16 11.8 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCM00947.1 - 1e-16 60.8 3.3 0.22 11.7 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCM00947.1 - 2.8e-13 49.7 0.0 2 8.4 0.0 5.8 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 CCM00947.1 - 8.2e-09 34.9 1.9 1.5 7.9 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase FlgD_ig PF13860.1 CCM00947.1 - 1.1e-08 34.6 8.0 4.6 7.0 0.0 5.3 5 0 0 5 5 5 5 FlgD Ig-like domain TUG-UBL1 PF11470.3 CCM00947.1 - 4.3e-07 29.7 7.9 9 6.3 0.0 5.2 5 0 0 5 5 5 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 CCM00947.1 - 6.4e-05 23.2 1.2 99 3.3 0.0 5.1 5 0 0 5 5 5 0 ACT domain Big_3_3 PF13750.1 CCM00947.1 - 0.00019 20.9 0.0 69 2.8 0.0 4.8 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 CCM00947.1 - 0.0037 15.6 18.4 5.4 5.1 0.2 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 CCM00947.1 - 0.017 15.0 19.3 12 5.9 0.2 5.6 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 CCM00947.1 - 0.025 14.4 38.3 4.5 7.3 1.2 5.3 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 CCM00947.1 - 0.073 13.0 10.8 75 3.4 0.1 4.9 5 0 0 5 5 5 0 GA-binding protein alpha chain DUF3781 PF12636.2 CCM00947.1 - 5 7.1 10.4 2.2e+02 1.8 0.1 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 CCM00947.1 - 7.6 6.6 17.8 1.2e+02 2.8 0.1 6.9 5 5 0 5 5 5 0 FERM N-terminal domain CDC48_2 PF02933.12 CCM00947.1 - 9.1 6.0 19.2 58 3.4 0.1 5.1 5 0 0 5 5 5 0 Cell division protein 48 (CDC48), domain 2 Fcf1 PF04900.7 CCM00948.1 - 5.2e-30 103.5 0.2 8.8e-30 102.7 0.1 1.4 1 0 0 1 1 1 1 Fcf1 DUF2012 PF09430.5 CCM00949.1 - 5.9e-19 68.1 0.0 9.2e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 CCM00949.1 - 0.0073 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SOBP PF15279.1 CCM00949.1 - 1.4 9.2 4.1 0.83 9.9 0.9 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein CAP PF00188.21 CCM00951.1 - 5.6e-19 68.8 0.4 1.2e-18 67.7 0.3 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF789 PF05623.7 CCM00951.1 - 0.026 14.0 1.0 0.078 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF789) FAD_binding_6 PF00970.19 CCM00952.1 - 4.4e-31 106.9 0.0 8.1e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCM00952.1 - 4.3e-30 104.4 0.0 1e-29 103.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain GST_N_3 PF13417.1 CCM00952.1 - 4.8e-10 39.5 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCM00952.1 - 5.4e-07 29.7 0.0 2.5e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain NAD_binding_6 PF08030.7 CCM00952.1 - 6.8e-07 29.3 0.0 1.6e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain GST_N_2 PF13409.1 CCM00952.1 - 1.2e-06 28.4 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FAD_binding_9 PF08021.6 CCM00952.1 - 0.0014 18.5 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain GST_C_2 PF13410.1 CCM00952.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DSPc PF00782.15 CCM00953.1 - 3.5e-11 42.8 0.0 1.2e-07 31.4 0.3 3.8 2 2 0 2 2 2 2 Dual specificity phosphatase, catalytic domain DUF846 PF05832.7 CCM00954.1 - 2.9e-53 179.3 9.0 3.5e-53 179.1 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.1 CCM00954.1 - 0.79 8.8 4.1 2.4 7.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) LRR_4 PF12799.2 CCM00956.1 - 2.3e-14 52.5 8.9 0.023 14.2 0.2 8.2 7 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CCM00956.1 - 2.5e-11 42.4 10.3 3 8.2 0.0 9.6 11 0 0 11 11 11 4 Leucine Rich repeat LRR_8 PF13855.1 CCM00956.1 - 6.9e-11 41.7 11.8 0.0008 19.1 0.0 6.3 5 2 1 7 7 7 4 Leucine rich repeat LRR_7 PF13504.1 CCM00956.1 - 0.12 12.6 15.4 70 4.3 0.1 8.5 10 1 0 10 10 10 0 Leucine rich repeat LRR_1 PF00560.28 CCM00956.1 - 3.4 8.0 16.9 91 3.7 0.0 7.7 9 2 0 9 9 9 0 Leucine Rich Repeat CcoS PF03597.10 CCM00957.1 - 0.35 10.3 2.8 1.5 8.3 1.9 2.1 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF89 PF01937.14 CCM00959.1 - 4.7e-107 357.8 0.0 5.4e-107 357.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Peptidase_M28 PF04389.12 CCM00960.1 - 5.2e-20 71.9 0.0 7.3e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCM00960.1 - 0.0023 17.4 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Lir1 PF07207.6 CCM00963.1 - 0.074 13.2 0.5 0.12 12.5 0.3 1.2 1 0 0 1 1 1 0 Light regulated protein Lir1 Amino_oxidase PF01593.19 CCM00964.1 - 5.4e-64 216.9 0.2 6.2e-50 170.5 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCM00964.1 - 2.6e-09 36.9 0.6 1.1e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCM00964.1 - 1.6e-05 25.0 1.6 0.00072 19.6 0.5 2.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM00964.1 - 0.001 18.0 0.7 0.049 12.5 0.7 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCM00964.1 - 0.001 18.2 0.2 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CCM00964.1 - 0.0019 18.5 0.9 0.28 11.6 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCM00964.1 - 0.0019 17.3 0.2 0.0028 16.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCM00964.1 - 0.0046 15.8 0.2 0.0092 14.8 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 CCM00964.1 - 0.063 13.3 0.1 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 CCM00964.1 - 0.075 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 CCM00964.1 - 0.09 12.3 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 CCM00964.1 - 0.21 10.3 0.1 0.37 9.5 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Amidohydro_2 PF04909.9 CCM00965.1 - 2.2e-30 106.1 0.0 3.5e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 CCM00965.1 - 0.00018 20.7 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase SET PF00856.23 CCM00966.1 - 6.4e-05 23.3 0.0 0.00052 20.3 0.0 2.1 1 1 0 1 1 1 1 SET domain SUI1 PF01253.17 CCM00967.1 - 4.4e-14 52.0 0.2 1.1e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 CCM00967.1 - 1.9e-07 30.7 0.1 4.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 PUA domain SWIB PF02201.13 CCM00967.1 - 0.016 14.8 0.1 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain SMP PF04927.7 CCM00969.1 - 0.00071 19.4 22.2 0.041 13.8 0.7 4.8 5 0 0 5 5 5 3 Seed maturation protein zf-C2H2_4 PF13894.1 CCM00970.1 - 0.00017 21.7 0.3 0.00017 21.7 0.2 3.4 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM00970.1 - 0.0012 19.0 0.4 0.0012 19.0 0.3 3.7 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-BED PF02892.10 CCM00970.1 - 0.062 13.0 1.6 0.15 11.8 0.7 2.0 1 1 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 CCM00970.1 - 1.3 9.4 3.8 25 5.3 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain RrnaAD PF00398.15 CCM00971.1 - 1.1e-60 204.9 0.0 1.5e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CCM00971.1 - 2.7e-10 40.3 0.0 4.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM00971.1 - 9.4e-07 29.4 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCM00971.1 - 1.2e-06 27.9 0.0 2.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CCM00971.1 - 0.0001 21.9 0.0 0.00037 20.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CCM00971.1 - 0.00011 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 CCM00971.1 - 0.00019 20.7 0.0 0.00035 19.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.7 CCM00971.1 - 0.00033 21.0 0.0 0.00069 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM00971.1 - 0.00063 19.4 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM00971.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCM00971.1 - 0.0015 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 CCM00971.1 - 0.02 13.7 0.1 0.042 12.7 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase Ubie_methyltran PF01209.13 CCM00971.1 - 0.043 12.9 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 CCM00971.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein NodS PF05401.6 CCM00971.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) BolA PF01722.13 CCM00972.1 - 1.2e-14 53.9 0.1 2.3e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 BolA-like protein BTB PF00651.26 CCM00973.1 - 3.8e-07 30.0 0.0 6.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MIP PF00230.15 CCM00974.1 - 5.6e-28 97.9 6.5 8.4e-28 97.3 4.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein F-box-like PF12937.2 CCM00975.1 - 0.0024 17.5 0.2 0.012 15.2 0.1 2.4 2 1 0 2 2 2 1 F-box-like Kelch_4 PF13418.1 CCM00976.1 - 1.4e-46 156.0 12.8 7.2e-08 32.0 0.6 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CCM00976.1 - 1.1e-40 136.9 20.3 3.1e-08 33.5 0.0 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CCM00976.1 - 1.9e-32 110.6 13.4 4.9e-10 39.1 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CCM00976.1 - 1.9e-26 91.3 10.3 2.7e-05 23.6 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CCM00976.1 - 2.5e-26 90.7 13.0 4.4e-05 23.4 0.0 6.3 1 1 5 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CCM00976.1 - 1.5e-17 62.5 13.5 1.5e-05 24.5 0.4 6.3 6 0 0 6 6 6 4 Kelch motif DUF1777 PF08648.7 CCM00976.1 - 0.065 12.9 14.2 0.1 12.3 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Herpes_BLLF1 PF05109.8 CCM00976.1 - 1.9 6.3 8.2 2.5 5.9 5.7 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF2201_N PF13203.1 CCM00977.1 - 0.13 11.3 2.8 0.28 10.3 2.0 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain MFS_1 PF07690.11 CCM00979.1 - 6.6e-22 77.7 27.4 1.3e-21 76.7 19.0 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 CCM00980.1 - 2.4e-11 42.9 28.9 2.4e-11 42.9 20.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 CCM00981.1 - 5.5e-72 242.7 0.0 1e-71 241.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 HSP20 PF00011.16 CCM00982.1 - 6e-22 77.4 0.0 8.7e-22 76.9 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 CCM00982.1 - 0.011 15.5 0.3 0.05 13.3 0.2 1.9 2 0 0 2 2 2 0 BON domain HMA PF00403.21 CCM00982.1 - 0.041 14.0 0.3 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 Heavy-metal-associated domain Rtt106 PF08512.7 CCM00983.1 - 1e-09 38.2 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF773 PF05600.7 CCM00983.1 - 6.4 5.4 4.6 11 4.6 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF773) WD40 PF00400.27 CCM00984.1 - 7.3e-45 149.3 10.2 9.1e-10 38.0 0.1 8.6 9 0 0 9 9 9 7 WD domain, G-beta repeat eIF2A PF08662.6 CCM00984.1 - 8.1e-06 25.6 0.0 0.33 10.6 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CCM00984.1 - 0.0012 18.4 0.8 8.3 6.1 0.0 5.4 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 CCM00984.1 - 0.0061 15.6 0.1 1.2 8.2 0.0 3.5 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 CCM00984.1 - 0.027 13.8 0.2 12 5.2 0.0 3.6 2 2 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Bac_rhamnosid PF05592.6 CCM00985.1 - 5.7e-27 94.1 2.4 1.3e-26 92.8 1.7 1.4 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 CCM00985.1 - 0.00099 17.9 6.0 0.0016 17.2 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Miro PF08477.8 CCM00986.1 - 0.00013 22.3 0.0 0.00054 20.4 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCM00986.1 - 0.0027 17.6 0.0 0.0093 15.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 CCM00986.1 - 0.0088 16.3 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain E1-N PF14463.1 CCM00986.1 - 0.037 13.6 0.6 0.067 12.7 0.4 1.3 1 0 0 1 1 1 0 E1 N-terminal domain DUF3399 PF11879.3 CCM00986.1 - 0.041 14.1 0.6 0.088 13.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) Arch_ATPase PF01637.13 CCM00986.1 - 0.049 13.3 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 CCM00986.1 - 0.062 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PqiA PF04403.8 CCM00986.1 - 0.064 12.8 1.4 0.11 12.0 1.0 1.3 1 0 0 1 1 1 0 Paraquat-inducible protein A G-alpha PF00503.15 CCM00986.1 - 0.068 11.8 0.3 0.69 8.5 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.8 CCM00986.1 - 0.096 11.5 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 CCM00986.1 - 0.14 12.1 0.1 0.57 10.1 0.1 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CCM00986.1 - 0.16 11.5 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain p450 PF00067.17 CCM00987.1 - 2.7e-58 197.6 0.0 3.6e-54 184.0 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Siva PF05458.7 CCM00987.1 - 0.046 13.2 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) GTP_cyclohydroI PF01227.17 CCM00987.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I p450 PF00067.17 CCM00988.1 - 1.1e-62 212.1 0.0 4.3e-62 210.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Siva PF05458.7 CCM00988.1 - 0.22 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) SWI-SNF_Ssr4 PF08549.5 CCM00989.1 - 5.6e-09 34.8 5.6 3.2e-06 25.7 0.0 2.4 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1750) Ribosomal_L44 PF00935.14 CCM00989.1 - 0.14 12.1 0.8 0.91 9.5 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein L44 Pyr_redox PF00070.22 CCM00990.1 - 6.3e-15 55.3 2.4 5.7e-11 42.6 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCM00990.1 - 2.3e-12 47.2 4.9 2.4e-11 43.9 3.4 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM00990.1 - 2.5e-09 37.4 0.0 3.1e-06 27.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM00990.1 - 1.4e-06 27.4 6.2 0.18 10.6 0.0 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM00990.1 - 1.7e-06 27.8 4.6 0.043 13.6 0.1 3.8 4 1 1 5 5 5 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 CCM00990.1 - 7.3e-06 25.1 0.0 0.0065 15.4 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CCM00990.1 - 4.8e-05 23.5 0.5 0.36 11.1 0.0 3.3 3 0 0 3 3 3 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 CCM00990.1 - 0.00019 20.1 0.9 0.035 12.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 CCM00990.1 - 0.00028 19.9 0.0 0.68 8.7 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.17 CCM00990.1 - 0.00056 18.8 1.3 7.4 5.3 0.1 3.9 4 0 0 4 4 4 1 Glucose inhibited division protein A TrkA_N PF02254.13 CCM00990.1 - 0.0037 17.2 0.2 0.3 11.1 0.1 2.5 2 0 0 2 2 2 1 TrkA-N domain CW_binding_2 PF04122.7 CCM00990.1 - 0.014 15.5 0.1 0.52 10.5 0.0 3.0 2 1 0 2 2 2 0 Putative cell wall binding repeat 2 NAD_binding_8 PF13450.1 CCM00990.1 - 0.015 15.2 0.7 0.93 9.5 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 CCM00990.1 - 0.037 14.1 0.1 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4147 PF13660.1 CCM00990.1 - 0.039 13.0 0.1 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) FAD_binding_2 PF00890.19 CCM00990.1 - 0.079 11.7 2.5 5.3 5.7 0.0 2.5 1 1 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 CCM00990.1 - 0.14 11.1 0.8 2.5 7.0 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain StbA PF06406.6 CCM00990.1 - 0.16 10.8 0.1 1.5 7.6 0.0 2.0 2 0 0 2 2 2 0 StbA protein Aldo_ket_red PF00248.16 CCM00991.1 - 2.2e-54 184.2 0.0 2.7e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Homeobox PF00046.24 CCM00991.1 - 0.023 14.3 0.1 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Homeobox domain HIT PF01230.18 CCM00992.1 - 6.7e-25 87.4 0.3 8.9e-25 87.0 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CCM00992.1 - 1.8e-13 50.7 0.2 2.4e-13 50.3 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CCM00992.1 - 5.9e-07 29.1 0.1 8.5e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 p450 PF00067.17 CCM00994.1 - 5.6e-51 173.5 0.0 1.7e-50 171.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 SAM_2 PF07647.12 CCM00995.1 - 1.1e-10 41.1 0.0 4e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCM00995.1 - 4.4e-08 33.1 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GSH_synth_ATP PF03917.12 CCM00996.1 - 9.2e-90 300.8 0.0 1.2e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CCM00996.1 - 1.5e-34 118.2 0.0 2.4e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Dynamin_N PF00350.18 CCM00997.1 - 1.7e-19 70.2 0.2 4.3e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CCM00997.1 - 1e-10 41.5 0.1 1e-09 38.3 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCM00997.1 - 2.7e-09 36.7 0.6 9.5e-08 31.6 0.4 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCM00997.1 - 0.00031 21.2 0.2 0.014 15.8 0.1 2.7 1 1 0 1 1 1 1 Miro-like protein IIGP PF05049.8 CCM00997.1 - 0.0054 15.6 0.1 0.0095 14.7 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 CCM00997.1 - 0.0074 15.7 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 CCM00997.1 - 0.012 15.0 0.2 0.96 8.8 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain adh_short PF00106.20 CCM00999.1 - 4.2e-17 62.5 2.2 7.5e-16 58.5 1.5 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM00999.1 - 5e-08 32.8 0.3 1e-07 31.8 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM00999.1 - 8.3e-08 32.2 0.0 0.0089 15.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCM00999.1 - 0.025 14.0 0.2 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 CCM00999.1 - 0.043 13.8 0.2 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain SYS1 PF09801.4 CCM00999.1 - 0.055 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network NAD_binding_10 PF13460.1 CCM00999.1 - 0.098 12.6 0.4 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 CCM01000.1 - 3.2e-61 207.2 0.0 6.9e-45 153.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Reticulon PF02453.12 CCM01000.1 - 0.012 15.1 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 Reticulon p450 PF00067.17 CCM01001.1 - 1.4e-64 218.3 0.0 3.1e-64 217.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM01002.1 - 2.2e-62 211.1 0.0 6.2e-62 209.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM01003.1 - 7.9e-62 209.2 0.0 3.5e-61 207.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM01004.1 - 4.5e-120 401.2 0.0 1.1e-60 205.4 0.0 3.1 1 1 1 2 2 2 2 Cytochrome P450 GTP_cyclohydroI PF01227.17 CCM01004.1 - 0.0048 16.1 0.0 3.2 7.0 0.0 2.3 2 0 0 2 2 2 2 GTP cyclohydrolase I DUF2834 PF11196.3 CCM01004.1 - 0.021 14.9 2.5 3.3 7.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) MRP PF09387.5 CCM01004.1 - 0.069 12.8 0.6 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial RNA binding protein MRP Baculo_p33 PF05214.7 CCM01004.1 - 0.24 10.6 0.0 18 4.5 0.0 2.2 2 0 0 2 2 2 0 Baculovirus P33 p450 PF00067.17 CCM01005.1 - 3.6e-60 203.8 0.0 1.2e-59 202.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 CCM01006.1 - 1.4e-12 47.8 6.8 1.1e-10 41.6 4.7 3.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM01006.1 - 7.3e-08 32.4 0.5 4.2e-05 23.4 0.0 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM01006.1 - 0.00097 18.8 3.3 0.14 11.8 2.3 2.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM01006.1 - 0.052 12.9 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MMR_HSR1 PF01926.18 CCM01007.1 - 9.5e-06 25.5 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCM01007.1 - 1.2e-05 25.7 0.0 6.4e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 CCM01007.1 - 0.022 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CCM01007.1 - 0.038 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 CCM01007.1 - 0.039 12.8 0.0 0.087 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CCM01007.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 CCM01007.1 - 0.079 12.9 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Sel1 PF08238.7 CCM01008.1 - 1.8e-30 104.6 39.1 3.8e-06 27.3 0.0 10.8 11 2 0 11 11 10 7 Sel1 repeat TPR_16 PF13432.1 CCM01008.1 - 1.1e-06 29.0 1.7 0.0014 19.2 0.1 8.0 9 2 2 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCM01008.1 - 3.7e-05 23.2 3.0 0.0012 18.4 0.2 4.4 4 1 2 6 6 6 3 TPR repeat TPR_12 PF13424.1 CCM01008.1 - 5.4e-05 23.0 0.3 0.003 17.4 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCM01008.1 - 0.0018 17.8 0.1 0.0018 17.8 0.1 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCM01008.1 - 0.0023 17.7 0.1 0.0023 17.7 0.1 6.7 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCM01008.1 - 0.0057 16.9 2.4 0.013 15.8 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM01008.1 - 0.0058 16.3 3.0 3.2 7.7 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCM01008.1 - 0.018 15.4 12.0 0.39 11.2 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCM01008.1 - 0.05 13.3 2.3 0.24 11.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2615 PF11027.3 CCM01008.1 - 0.085 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) TPR_14 PF13428.1 CCM01008.1 - 0.089 13.4 0.1 0.089 13.4 0.0 6.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCM01008.1 - 0.095 12.9 0.4 11 6.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2361 PF10153.4 CCM01009.1 - 1.1e-28 99.6 12.2 2.3e-28 98.6 8.5 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) Mnd1 PF03962.10 CCM01009.1 - 0.028 14.0 6.1 0.049 13.2 4.2 1.5 1 0 0 1 1 1 0 Mnd1 family Spc7 PF08317.6 CCM01009.1 - 0.1 11.2 4.9 0.16 10.6 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.6 CCM01009.1 - 0.14 12.0 1.3 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.11 CCM01009.1 - 4.2 7.6 8.9 4.6 7.5 5.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 CENP-Q PF13094.1 CCM01009.1 - 5.6 6.9 17.5 0.067 13.2 2.4 3.0 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Caps_synth_GfcC PF06251.6 CCM01009.1 - 9.6 5.2 10.0 10 5.2 1.8 2.2 1 1 1 2 2 2 0 Capsule biosynthesis GfcC Bromodomain PF00439.20 CCM01012.1 - 2.5e-20 72.1 0.5 1.5e-19 69.6 0.2 2.3 1 1 1 2 2 2 1 Bromodomain Bromo_TP PF07524.8 CCM01012.1 - 2.3e-06 27.2 0.0 5.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated WD40 PF00400.27 CCM01013.1 - 3.3e-32 109.1 9.6 1.1e-06 28.3 0.0 6.8 6 1 1 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CCM01013.1 - 0.00036 20.2 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CCM01013.1 - 0.037 13.1 0.0 0.59 9.1 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal FAD_binding_4 PF01565.18 CCM01014.1 - 1.8e-10 40.4 0.1 0.00029 20.3 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.7 CCM01014.1 - 4.1e-05 23.3 0.1 8.3e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 CCM01014.1 - 0.026 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Cut8_N PF14482.1 CCM01014.1 - 0.68 9.9 4.7 7.8 6.5 0.3 2.7 2 0 0 2 2 2 0 Cut8 proteasome-binding domain RhoGEF PF00621.15 CCM01015.1 - 1.1e-32 113.3 0.0 2.1e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 CCM01015.1 - 0.0002 20.9 0.1 0.0031 17.0 0.1 2.2 1 1 0 1 1 1 1 BAR domain Zip PF02535.17 CCM01015.1 - 0.79 8.6 2.0 1.4 7.8 1.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter E1-E2_ATPase PF00122.15 CCM01016.1 - 6.5e-77 257.6 0.8 1.2e-76 256.8 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCM01016.1 - 4.4e-36 124.0 2.1 4.4e-36 124.0 1.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCM01016.1 - 5.2e-30 105.4 0.0 2e-29 103.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCM01016.1 - 1.6e-15 56.8 0.0 9.4e-15 54.3 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCM01016.1 - 3.8e-15 56.5 0.0 1.1e-14 55.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCM01016.1 - 1.9e-10 40.0 0.0 4.8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCM01016.1 - 1.7e-05 24.5 2.3 0.00086 18.9 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 CCM01016.1 - 0.0046 16.5 0.0 0.0046 16.5 0.0 2.4 3 0 0 3 3 3 1 Positive regulator of sigma(E), RseC/MucC CoA_transf_3 PF02515.12 CCM01017.1 - 5e-45 153.1 0.0 9.3e-45 152.2 0.0 1.5 2 0 0 2 2 2 1 CoA-transferase family III Lactonase PF10282.4 CCM01018.1 - 1.2e-53 182.3 0.0 1.4e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DHQS PF01959.11 CCM01018.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) Tic20 PF09685.5 CCM01020.1 - 0.51 10.3 20.3 1 9.3 2.3 2.5 1 1 1 2 2 2 0 Tic20-like protein DUF3366 PF11846.3 CCM01020.1 - 1 9.2 8.4 1 9.1 0.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) Aldo_ket_red PF00248.16 CCM01021.1 - 1.4e-51 174.9 0.0 1.7e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MNE1 PF13762.1 CCM01021.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component Shikimate_DH PF01488.15 CCM01021.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EF-hand_1 PF00036.27 CCM01023.1 - 2.3e-23 79.6 0.5 1.2e-05 24.2 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CCM01023.1 - 4.3e-21 72.8 0.3 5.2e-06 25.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CCM01023.1 - 1.2e-17 62.2 2.4 0.00062 18.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCM01023.1 - 3.2e-17 62.4 0.1 2.8e-08 33.7 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CCM01023.1 - 4.7e-12 45.3 6.0 1.7e-07 30.7 0.1 4.2 3 3 2 5 5 5 5 EF-hand domain pair Toprim_2 PF13155.1 CCM01023.1 - 0.0036 17.5 0.0 3.4 8.0 0.0 2.5 1 1 2 3 3 3 2 Toprim-like EF-hand_2 PF09068.6 CCM01023.1 - 0.059 13.4 0.0 26 4.9 0.0 3.1 3 0 0 3 3 3 0 EF hand EF-hand_9 PF14658.1 CCM01023.1 - 0.085 12.7 0.0 20 5.1 0.0 3.0 3 1 0 3 3 3 0 EF-hand domain Peptidase_M22 PF00814.20 CCM01024.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family TMPIT PF07851.8 CCM01025.1 - 0.017 14.2 0.6 0.017 14.2 0.4 2.1 1 1 1 2 2 2 0 TMPIT-like protein DivIVA PF05103.8 CCM01025.1 - 0.79 9.7 22.7 0.61 10.1 5.5 2.4 2 0 0 2 2 2 0 DivIVA protein Rota_VP2 PF05087.7 CCM01025.1 - 1.1 7.0 10.6 1.5 6.6 7.4 1.2 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF3584 PF12128.3 CCM01025.1 - 4.9 4.3 29.2 6.8 3.8 20.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Aldo_ket_red PF00248.16 CCM01026.1 - 1.7e-72 243.6 0.0 2e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Asp PF00026.18 CCM01028.1 - 2.9e-25 89.2 11.4 2.2e-24 86.2 7.9 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM01028.1 - 8.8e-07 29.0 2.0 8.3e-05 22.5 1.4 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal ATP-synt_S1 PF05827.7 CCM01029.1 - 1.4e-14 54.0 0.7 8.9e-12 44.9 0.0 2.0 1 1 1 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Peptidase_M24 PF00557.19 CCM01030.1 - 7e-56 189.0 0.3 9.8e-56 188.6 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCM01030.1 - 7.1e-33 112.8 0.0 1.5e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain AA_permease_2 PF13520.1 CCM01031.1 - 5.9e-45 153.5 49.8 7.7e-45 153.1 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCM01031.1 - 2.3e-20 72.3 40.0 3.2e-20 71.9 27.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1469 PF07332.6 CCM01031.1 - 0.2 11.3 0.1 0.2 11.3 0.1 4.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) GTP_EFTU PF00009.22 CCM01032.1 - 8.2e-33 113.4 0.0 3.6e-32 111.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCM01032.1 - 1.4e-17 63.4 0.0 3.5e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCM01032.1 - 2e-12 47.0 8.4 3.2e-09 36.7 0.1 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCM01032.1 - 1.4e-06 28.2 0.0 5.6e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CCM01032.1 - 0.0011 18.5 0.0 0.005 16.4 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 CCM01032.1 - 0.0051 16.9 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ras PF00071.17 CCM01032.1 - 0.038 13.3 0.0 0.16 11.3 0.0 2.1 1 1 0 1 1 1 0 Ras family AAA_16 PF13191.1 CCM01032.1 - 0.29 11.0 0.0 0.29 11.0 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain Arf PF00025.16 CCM01033.1 - 1.3e-70 236.1 0.1 1.5e-70 235.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CCM01033.1 - 2.1e-12 46.4 1.3 2.2e-06 26.6 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCM01033.1 - 4.1e-10 39.1 0.0 5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCM01033.1 - 1.8e-09 37.0 0.0 2.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CCM01033.1 - 5.4e-07 29.1 0.0 6.9e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CCM01033.1 - 7.5e-07 29.1 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCM01033.1 - 6.1e-05 23.4 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CCM01033.1 - 8.3e-05 22.0 0.0 0.0039 16.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CCM01033.1 - 0.024 14.1 0.1 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 CCM01033.1 - 0.12 13.1 0.1 0.25 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Asp PF00026.18 CCM01034.1 - 2.4e-38 132.1 0.1 1.9e-37 129.1 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM01034.1 - 0.0081 16.1 0.1 0.6 10.0 0.1 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal RF-1 PF00472.15 CCM01035.1 - 2e-34 117.8 1.2 4.3e-34 116.7 0.8 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CCM01035.1 - 1.6e-25 89.0 0.0 3.3e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 PCRF domain Mito_carr PF00153.22 CCM01036.1 - 3e-48 161.4 2.0 8.7e-21 73.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.19 CCM01037.1 - 4e-45 153.5 3.1 4e-45 153.5 2.2 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CCM01037.1 - 5.2e-29 101.1 1.4 1.2e-28 99.9 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCM01037.1 - 1.8e-21 76.7 2.0 1.8e-21 76.7 1.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCM01037.1 - 4.5e-20 70.9 0.0 1.4e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CCM01037.1 - 0.0047 17.2 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal DUF2433 PF10360.4 CCM01038.1 - 4.4e-31 107.9 0.0 7.7e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 CCM01038.1 - 0.0004 20.2 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCM01038.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 CCM01038.1 - 0.47 8.8 7.1 0.71 8.2 4.9 1.2 1 0 0 1 1 1 0 Daxx Family Med13_C PF06333.7 CCM01039.1 - 4e-16 58.5 0.5 4e-16 58.5 0.3 3.3 3 1 0 3 3 3 2 Mediator complex subunit 13 C-terminal DUF336 PF03928.9 CCM01040.1 - 8.8e-21 74.0 0.0 1.1e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) BolA PF01722.13 CCM01041.1 - 5.3e-19 67.9 0.0 6.9e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein COX15-CtaA PF02628.10 CCM01042.1 - 3.3e-94 315.1 11.7 4.1e-94 314.8 8.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Proteasome PF00227.21 CCM01043.1 - 7.7e-52 175.3 0.0 1e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCM01043.1 - 7.2e-11 41.1 1.7 1.2e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature CsoSCA PF08936.5 CCM01047.1 - 0.072 11.4 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase F-box-like PF12937.2 CCM01048.1 - 0.061 13.0 0.1 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 CCM01048.1 - 0.081 12.6 0.9 38 4.1 0.2 3.4 3 0 0 3 3 3 0 F-box domain Abhydrolase_3 PF07859.8 CCM01049.1 - 3.7e-21 75.6 0.0 4.9e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCM01049.1 - 7.3e-09 34.7 0.0 2.6e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 CCM01049.1 - 1e-06 28.8 0.1 1.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM01049.1 - 0.00042 20.0 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CCM01049.1 - 0.047 13.0 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 CCM01049.1 - 0.096 11.8 0.0 0.5 9.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Catalase PF00199.14 CCM01050.1 - 9.2e-182 603.9 0.4 1.1e-181 603.6 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCM01050.1 - 1e-15 57.3 0.8 1.7e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Ribosomal_L14 PF00238.14 CCM01051.1 - 2.4e-28 98.3 0.0 1.9e-17 63.1 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein L14p/L23e RRM_1 PF00076.17 CCM01052.1 - 1.3e-11 43.8 0.1 2.6e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM01052.1 - 3.9e-10 39.5 0.4 1.5e-09 37.6 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM01052.1 - 4.8e-06 26.3 0.1 0.00044 20.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 CCM01053.1 - 0.00036 20.7 14.5 0.018 15.3 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM01053.1 - 0.00044 20.3 16.5 0.02 15.1 0.7 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zinc_ribbon_5 PF13719.1 CCM01053.1 - 0.0094 15.5 1.4 3.2 7.3 0.0 2.5 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCM01053.1 - 0.015 15.0 1.7 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 CCM01053.1 - 0.024 14.7 1.7 0.95 9.6 0.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 CCM01053.1 - 0.13 12.3 3.9 3.7 7.6 0.5 2.7 2 0 0 2 2 2 0 zinc-finger Zn-ribbon_8 PF09723.5 CCM01053.1 - 0.26 11.2 3.9 1 9.3 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 CCM01053.1 - 2.5 8.5 9.8 5.6 7.4 0.6 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 CCM01053.1 - 5.4 6.3 7.6 1.4e+02 1.8 0.2 2.4 1 1 1 2 2 2 0 zinc-ribbon domain HAD_2 PF13419.1 CCM01054.1 - 3e-22 79.6 0.0 3.6e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Flo11 PF10182.4 CCM01054.1 - 0.069 12.7 0.0 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 Flo11 domain Acetyltransf_3 PF13302.1 CCM01055.1 - 3.1e-07 30.6 0.0 4.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM01055.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Methyltransf_18 PF12847.2 CCM01056.1 - 0.0045 17.5 0.0 0.047 14.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Cupin_5 PF06172.6 CCM01057.1 - 4.8e-25 88.0 0.0 6.5e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) ADH_zinc_N PF00107.21 CCM01058.1 - 3.3e-14 52.5 0.0 7.8e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 CCM01058.1 - 0.17 11.0 0.1 0.55 9.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) ADH_zinc_N PF00107.21 CCM01059.1 - 7.7e-18 64.2 0.0 2.3e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM01059.1 - 2.7e-07 31.5 0.0 3.6e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 CCM01059.1 - 0.003 17.5 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain DUF2855 PF11017.3 CCM01059.1 - 0.073 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) ADH_N PF08240.7 CCM01060.1 - 5.2e-28 96.9 1.3 8.8e-28 96.2 0.4 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM01060.1 - 1.2e-22 79.8 1.4 2.8e-22 78.6 0.2 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 CCM01060.1 - 0.00043 20.2 0.1 0.00083 19.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.1 CCM01060.1 - 0.0038 17.3 0.1 0.0059 16.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_N_assoc PF13823.1 CCM01060.1 - 0.0056 16.3 0.2 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated F420_oxidored PF03807.12 CCM01060.1 - 0.023 15.1 0.1 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_11 PF08241.7 CCM01060.1 - 0.072 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 CCM01060.1 - 0.073 12.9 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 CCM01061.1 - 1.6e-29 101.8 2.6 3.4e-29 100.7 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM01061.1 - 6.8e-22 77.4 0.1 1.3e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 CCM01061.1 - 0.11 12.3 1.5 0.26 11.1 0.4 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM01061.1 - 0.14 12.1 0.3 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 CCM01062.1 - 5.9e-30 103.2 3.0 1e-29 102.4 1.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM01062.1 - 7.5e-21 74.0 0.1 7.5e-21 74.0 0.1 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 CCM01062.1 - 0.023 14.7 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ADH_N_assoc PF13823.1 CCM01062.1 - 0.035 13.7 0.1 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated HET PF06985.6 CCM01063.1 - 6.1e-18 65.3 6.5 1.7e-15 57.3 0.5 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 CCM01064.1 - 0.00076 19.1 9.5 0.36 10.6 0.2 3.6 3 0 0 3 3 3 2 F-box-like tRNA_anti_2 PF13742.1 CCM01064.1 - 0.012 15.4 0.0 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF607 PF04678.8 CCM01064.1 - 0.084 12.7 0.5 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF607 F-box-like PF12937.2 CCM01065.1 - 0.011 15.5 1.0 0.034 13.8 0.7 2.0 1 0 0 1 1 1 0 F-box-like CDRN PF05174.7 CCM01073.1 - 0.11 11.9 0.0 0.38 10.2 0.0 1.8 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus F-box-like PF12937.2 CCM01074.1 - 3.4e-08 33.0 0.0 7.1e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 CCM01074.1 - 0.0058 16.2 0.9 0.65 9.7 0.2 2.4 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 CCM01075.1 - 6.2e-10 38.6 1.6 1.8e-09 37.1 1.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM01075.1 - 0.019 14.5 4.8 1.8 8.3 0.2 2.9 2 0 0 2 2 2 0 F-box domain zf-C2H2_4 PF13894.1 CCM01076.1 - 0.00091 19.4 0.1 2.7 8.5 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM01076.1 - 0.019 15.2 0.1 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type F-box-like PF12937.2 CCM01077.1 - 6.5e-06 25.7 0.0 1.7e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like zf-C2H2 PF00096.21 CCM01078.1 - 9.1e-07 28.8 1.0 0.0032 17.7 0.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM01078.1 - 2.9e-05 24.1 0.3 0.028 14.7 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger GATA PF00320.22 CCM01080.1 - 0.0012 18.1 0.4 0.0012 18.1 0.3 1.7 2 0 0 2 2 2 1 GATA zinc finger zf-MYND PF01753.13 CCM01081.1 - 3.4e-10 39.6 6.9 5.3e-10 39.0 4.8 1.3 1 0 0 1 1 1 1 MYND finger DUF3251 PF11622.3 CCM01081.1 - 0.1 11.9 0.2 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) zf-HIT PF04438.11 CCM01081.1 - 0.84 9.3 5.6 1.5 8.5 3.9 1.5 1 0 0 1 1 1 0 HIT zinc finger DUF4470 PF14737.1 CCM01082.1 - 2.8e-19 68.6 0.0 4.4e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Exo_endo_phos_2 PF14529.1 CCM01082.1 - 0.061 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase F-box-like PF12937.2 CCM01083.1 - 0.0066 16.1 0.8 0.0066 16.1 0.6 2.2 2 0 0 2 2 2 1 F-box-like Colicin_C PF12106.3 CCM01084.1 - 0.037 13.6 2.4 0.066 12.7 0.6 2.3 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain UCH PF00443.24 CCM01085.1 - 1.2e-60 204.9 0.0 1.7e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM01085.1 - 3.2e-21 76.0 0.0 4.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.15 CCM01085.1 - 0.00079 18.8 0.4 0.0033 16.9 0.1 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger RicinB_lectin_2 PF14200.1 CCM01085.1 - 0.0022 18.3 0.4 0.036 14.4 0.1 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF2365 PF10157.4 CCM01085.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) p450 PF00067.17 CCM01086.1 - 6.9e-63 212.7 0.0 1.8e-62 211.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 G-alpha PF00503.15 CCM01087.1 - 2.7e-95 319.3 0.4 2.2e-91 306.4 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit PARP PF00644.15 CCM01087.1 - 6.9e-13 48.4 1.0 3.7e-09 36.3 0.1 3.1 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Arf PF00025.16 CCM01087.1 - 8.3e-07 28.4 0.1 0.0014 17.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 CCM01087.1 - 0.002 17.5 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCM01087.1 - 0.07 12.6 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RAM PF15320.1 CCM01087.1 - 0.093 13.0 0.7 0.27 11.5 0.5 1.7 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein AAA_22 PF13401.1 CCM01087.1 - 0.12 12.5 0.0 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain zf-FCS PF06467.9 CCM01087.1 - 0.43 10.2 14.3 0.074 12.7 1.2 3.7 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF329 PF03884.9 CCM01087.1 - 3.7 7.1 10.9 2.8 7.5 2.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF329) E1-E2_ATPase PF00122.15 CCM01088.1 - 5.3e-52 176.1 3.0 8.1e-52 175.5 2.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCM01088.1 - 8.4e-30 104.7 0.0 1.3e-28 100.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCM01088.1 - 5.6e-19 67.8 0.0 1.1e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCM01088.1 - 3.1e-16 60.1 0.0 9.3e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCM01088.1 - 9.5e-11 41.0 0.0 2.2e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCM01088.1 - 8.7e-08 32.0 0.2 1.8e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CCM01088.1 - 1.1e-07 31.6 0.0 1.1e-07 31.6 0.0 3.0 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus PI3K_C2 PF00792.19 CCM01088.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 COesterase PF00135.23 CCM01089.1 - 5e-28 98.1 0.0 5.7e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family F-box-like PF12937.2 CCM01090.1 - 5.8e-08 32.3 1.2 1.7e-07 30.8 0.8 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CCM01090.1 - 0.0051 16.4 0.5 2.2 7.9 0.2 3.9 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box PF00646.28 CCM01090.1 - 0.059 13.0 0.6 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 CCM01091.1 - 3.8e-08 32.9 2.7 1.3e-07 31.2 1.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM01091.1 - 0.025 14.2 0.1 0.18 11.5 0.0 2.5 2 1 0 2 2 2 0 F-box domain CAP59_mtransfer PF11735.3 CCM01092.1 - 5.8e-61 205.7 0.0 8.1e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 WD40 PF00400.27 CCM01095.1 - 2.1e-154 496.5 78.9 1.1e-12 47.2 0.1 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat PQQ_3 PF13570.1 CCM01095.1 - 9.5e-13 47.9 14.5 1.4 9.3 0.0 11.9 8 4 6 14 14 14 3 PQQ-like domain Nucleoporin_N PF08801.6 CCM01095.1 - 6.8e-09 34.9 38.3 0.026 13.2 3.8 11.1 1 1 7 10 10 10 5 Nup133 N terminal like PQQ_2 PF13360.1 CCM01095.1 - 1.4e-07 31.2 14.8 0.009 15.4 0.6 4.5 1 1 2 3 3 3 2 PQQ-like domain DUF3312 PF11768.3 CCM01095.1 - 0.11 10.6 0.0 4.9 5.2 0.0 3.5 3 1 1 5 5 5 0 Protein of unknown function (DUF3312) SpoVA PF03862.8 CCM01095.1 - 0.28 11.3 0.0 14 5.8 0.0 3.5 3 2 2 5 5 5 0 SpoVA protein APH PF01636.18 CCM01096.1 - 0.00014 21.6 0.1 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CCM01096.1 - 0.012 14.8 0.1 0.083 12.0 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain NB-ARC PF00931.17 CCM01097.1 - 0.00026 19.9 0.0 0.00058 18.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 CCM01097.1 - 0.0036 17.4 0.2 0.14 12.3 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCM01097.1 - 0.0037 16.9 0.4 0.014 15.0 0.3 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CCM01097.1 - 0.013 15.6 0.2 0.41 10.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 CCM01097.1 - 0.047 12.5 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glutaredoxin2_C PF04399.8 CCM01097.1 - 0.064 12.8 0.1 0.19 11.3 0.1 1.8 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain F-box PF00646.28 CCM01099.1 - 0.052 13.2 0.2 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 F-box domain RicinB_lectin_2 PF14200.1 CCM01100.1 - 7.9e-05 22.9 0.1 0.0066 16.8 0.0 2.4 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF2146 PF10220.4 CCM01100.1 - 0.8 7.6 8.0 1 7.2 5.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) CDC45 PF02724.9 CCM01100.1 - 1.3 6.9 12.6 1.8 6.4 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein RicinB_lectin_2 PF14200.1 CCM01101.1 - 6.2e-11 42.6 0.3 2.4e-05 24.6 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.1 CCM01102.1 - 5.6e-08 33.0 2.0 1.1e-05 25.7 0.2 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like MRJP PF03022.11 CCM01104.1 - 4.9e-24 85.0 0.0 8.6e-24 84.2 0.0 1.3 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 CCM01104.1 - 1e-06 28.3 0.0 4.7e-06 26.1 0.0 2.0 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region HSF_DNA-bind PF00447.12 CCM01107.1 - 1.5e-34 118.3 0.5 2.2e-34 117.7 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding APC8 PF04049.8 CCM01108.1 - 8.1e-22 77.4 0.0 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 CCM01108.1 - 3.7e-17 61.7 1.5 2.4e-08 33.5 0.8 3.7 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 CCM01108.1 - 3.1e-16 58.1 0.5 0.00059 19.3 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCM01108.1 - 6.5e-14 50.6 2.2 0.0031 17.3 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCM01108.1 - 4.2e-10 39.3 6.1 0.019 15.5 0.0 6.8 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCM01108.1 - 1.1e-08 34.2 1.2 0.0043 16.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM01108.1 - 9.7e-08 32.4 3.0 0.11 13.2 0.0 5.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM01108.1 - 1.9e-07 30.8 4.9 0.0044 16.9 1.1 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CCM01108.1 - 1e-05 25.6 6.8 0.03 14.4 1.3 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCM01108.1 - 7.2e-05 22.3 1.4 1.1 9.2 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCM01108.1 - 0.0022 17.8 0.2 4.5 7.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCM01108.1 - 0.018 15.4 0.1 55 4.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCM01108.1 - 0.024 14.7 0.1 1.5e+02 2.9 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.5 CCM01108.1 - 0.035 12.8 0.4 0.22 10.2 0.0 2.1 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Glyco_hydro_11 PF00457.12 CCM01108.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 GLTSCR1 PF15249.1 CCM01109.1 - 1.5e-21 76.4 0.7 2.5e-21 75.7 0.0 1.7 2 0 0 2 2 2 1 Glioma tumor suppressor candidate region F-box-like PF12937.2 CCM01110.1 - 0.00013 21.5 1.4 0.0009 18.9 0.1 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 CCM01110.1 - 0.0019 17.8 0.0 0.0053 16.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.13 CCM01111.1 - 1e-22 80.3 0.0 1.9e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM01111.1 - 4.8e-08 32.7 8.8 7.7e-08 32.1 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 CCM01111.1 - 0.058 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF1674 PF07896.7 CCM01112.1 - 1.1e-10 41.5 0.1 1.9e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) DEAD PF00270.24 CCM01114.1 - 4.2e-37 127.2 0.0 6.4e-36 123.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM01114.1 - 2e-23 82.0 0.5 7e-23 80.2 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CCM01114.1 - 1.7e-20 72.5 2.2 1.7e-20 72.5 1.6 2.3 2 0 0 2 2 2 1 DBP10CT (NUC160) domain IL10 PF00726.12 CCM01114.1 - 0.15 11.3 1.0 0.33 10.2 0.7 1.5 1 0 0 1 1 1 0 Interleukin 10 TGT PF01702.13 CCM01115.1 - 1.5e-79 266.6 0.0 1.9e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Omega_Repress PF07764.6 CCM01115.1 - 0.1 12.9 0.5 0.39 11.0 0.1 2.0 2 0 0 2 2 2 0 Omega Transcriptional Repressor tRNA-synt_1b PF00579.20 CCM01116.1 - 1.8e-72 243.9 0.0 2.3e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 CCM01116.1 - 1e-06 28.0 0.0 2.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain EMP70 PF02990.11 CCM01117.1 - 9.5e-186 618.2 0.0 1.2e-185 617.8 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 F-box-like PF12937.2 CCM01118.1 - 8.2e-05 22.2 0.0 0.00024 20.7 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM01118.1 - 0.00027 20.4 0.0 0.00073 19.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain BAR PF03114.13 CCM01120.1 - 5e-45 153.7 0.8 3.2e-44 151.1 0.5 1.9 1 1 0 1 1 1 1 BAR domain Metal_resist PF13801.1 CCM01120.1 - 0.092 12.7 0.6 1 9.3 0.0 2.7 3 0 0 3 3 3 0 Heavy-metal resistance ELH PF02323.10 CCM01120.1 - 0.12 11.5 0.1 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor DUF2367 PF10164.4 CCM01122.1 - 2.5e-06 27.2 5.6 2.5e-06 27.2 3.9 2.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2367) adh_short PF00106.20 CCM01123.1 - 7.9e-19 68.1 0.1 2.1e-18 66.7 0.1 1.7 2 0 0 2 2 1 1 short chain dehydrogenase Methyltransf_31 PF13847.1 CCM01123.1 - 7.1e-15 54.8 0.2 1.4e-13 50.6 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM01123.1 - 4.9e-12 46.4 0.0 1.2e-10 41.9 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM01123.1 - 5.1e-11 42.9 0.0 1.5e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCM01123.1 - 6.2e-11 41.9 0.0 9.9e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CCM01123.1 - 8.1e-09 35.5 0.0 8.2e-08 32.2 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain KR PF08659.5 CCM01123.1 - 2.8e-08 33.6 0.1 5.7e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_23 PF13489.1 CCM01123.1 - 8e-08 32.1 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCM01123.1 - 1.2e-07 30.7 0.0 1.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 CCM01123.1 - 5.4e-07 29.8 0.0 1.2e-05 25.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCM01123.1 - 8e-07 28.5 0.1 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain adh_short_C2 PF13561.1 CCM01123.1 - 2.9e-06 27.2 0.0 4.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_12 PF08242.7 CCM01123.1 - 1.2e-05 25.6 0.0 3.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CCM01123.1 - 1.7e-05 24.8 0.0 0.0015 18.5 0.0 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.15 CCM01123.1 - 1.9e-05 23.8 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 CCM01123.1 - 0.00011 21.4 0.0 0.00023 20.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PRMT5 PF05185.11 CCM01123.1 - 0.00054 18.9 0.0 0.0008 18.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.14 CCM01123.1 - 0.0025 17.3 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 CCM01123.1 - 0.0048 16.0 0.1 0.011 14.8 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 CCM01123.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 CCM01123.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_16 PF10294.4 CCM01123.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 CCM01123.1 - 0.024 15.4 0.0 0.16 12.8 0.0 2.5 3 0 0 3 3 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 CCM01123.1 - 0.13 11.2 0.1 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 CCM01123.1 - 0.14 11.7 0.1 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 CCM01123.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 WD40 PF00400.27 CCM01124.1 - 1.2e-60 199.3 26.4 3.9e-11 42.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CCM01124.1 - 0.00043 18.5 6.5 0.077 11.1 0.4 3.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 CCM01124.1 - 0.0049 16.4 1.2 21 4.9 0.0 4.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 CCM01124.1 - 0.019 13.2 0.1 1.1 7.5 0.1 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF1416 PF07210.7 CCM01124.1 - 0.03 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) IU_nuc_hydro PF01156.14 CCM01125.1 - 4.8e-55 186.9 0.0 6.1e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MFS_1 PF07690.11 CCM01126.1 - 5.7e-16 58.1 35.6 9.1e-16 57.5 24.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily bZIP_1 PF00170.16 CCM01128.1 - 3.7e-06 26.7 1.7 8.4e-06 25.6 1.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCM01128.1 - 0.0015 18.3 3.1 0.0026 17.5 2.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.8 CCM01128.1 - 0.046 12.6 0.3 0.068 12.1 0.2 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Cast PF10174.4 CCM01128.1 - 0.062 11.3 0.6 0.08 10.9 0.4 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone EXS PF03124.9 CCM01131.1 - 3.2e-51 174.3 0.1 4.1e-51 174.0 0.1 1.1 1 0 0 1 1 1 1 EXS family 2-Hacid_dh_C PF02826.14 CCM01131.1 - 5.1e-47 159.3 0.0 7.2e-47 158.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCM01131.1 - 3.4e-17 62.1 0.0 5.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Bromodomain PF00439.20 CCM01133.1 - 5e-26 90.4 0.3 9.1e-26 89.5 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CCM01133.1 - 3.8e-07 30.1 0.3 8.2e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM01133.1 - 1.1e-05 25.3 0.1 2.6e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCM01133.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DPBB_1 PF03330.13 CCM01134.1 - 2.3e-06 27.4 0.0 6.1e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF952 PF06108.7 CCM01135.1 - 2.6e-25 88.0 0.0 3.2e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Pro_isomerase PF00160.16 CCM01136.1 - 6e-47 159.7 0.1 7.2e-47 159.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 CCM01137.1 - 7.1e-36 123.2 0.0 1.3e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCM01137.1 - 1.5e-17 62.9 0.5 6.3e-17 60.8 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCM01137.1 - 3.2e-16 58.9 0.0 8.2e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM01137.1 - 0.0072 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MOZ_SAS PF01853.13 CCM01138.1 - 4.7e-79 264.0 0.2 6.6e-79 263.5 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CCM01138.1 - 2.4e-18 65.5 0.0 4.5e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 CCM01138.1 - 0.0053 16.7 0.0 0.086 12.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family HTH_11 PF08279.7 CCM01138.1 - 0.0092 15.6 0.0 0.028 14.0 0.0 1.8 1 0 0 1 1 1 1 HTH domain zf-C2H2 PF00096.21 CCM01138.1 - 0.24 11.8 2.5 0.56 10.6 1.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CCM01138.1 - 0.28 11.5 1.3 0.6 10.4 0.9 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain LAG1-DNAbind PF09271.6 CCM01140.1 - 3.3e-34 118.3 0.0 6.3e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 CCM01140.1 - 6.5e-23 81.2 0.0 9.6e-21 74.1 0.0 2.9 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain Pkinase PF00069.20 CCM01143.1 - 7.1e-52 176.1 0.3 3.2e-51 174.0 0.2 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01143.1 - 5e-22 78.2 0.0 8.1e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM01143.1 - 0.0007 19.3 0.1 0.0007 19.3 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCM01143.1 - 0.0016 17.8 0.1 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CCM01143.1 - 0.084 12.4 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Put_Phosphatase PF06888.7 CCM01144.1 - 1.3e-07 31.0 0.3 1.5e-07 30.8 0.2 1.0 1 0 0 1 1 1 1 Putative Phosphatase BSD PF03909.12 CCM01145.1 - 3e-17 62.1 0.3 1.3e-14 53.6 0.0 2.7 2 0 0 2 2 2 2 BSD domain YCII PF03795.9 CCM01146.1 - 3.4e-11 43.1 0.0 4.3e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DnaB PF00772.16 CCM01146.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain CASP_C PF08172.7 CCM01147.1 - 3.8e-71 239.0 2.3 3.8e-71 239.0 1.6 4.1 2 1 2 4 4 4 1 CASP C terminal CtIP_N PF10482.4 CCM01147.1 - 0.0038 17.0 0.7 0.0038 17.0 0.5 5.3 3 1 1 5 5 5 1 Tumour-suppressor protein CtIP N-terminal domain Shugoshin_N PF07558.6 CCM01147.1 - 0.2 11.4 0.1 0.2 11.4 0.1 4.5 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region IncA PF04156.9 CCM01147.1 - 1.5 8.3 63.8 0.36 10.4 0.3 5.6 3 1 1 4 4 4 0 IncA protein Ribosomal_S9 PF00380.14 CCM01148.1 - 7e-32 110.2 0.0 1.7e-31 108.9 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S30 PF04758.9 CCM01148.1 - 1.9 8.2 6.6 7.7 6.3 1.2 3.1 3 0 0 3 3 3 0 Ribosomal protein S30 BRE1 PF08647.6 CCM01149.1 - 4.3e-16 58.6 9.9 4.3e-16 58.6 6.9 6.2 2 2 4 6 6 6 1 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 CCM01149.1 - 0.011 14.9 0.1 0.011 14.9 0.1 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein TMEM192 PF14802.1 CCM01149.1 - 0.76 8.5 10.6 0.15 10.8 0.2 3.6 4 0 0 4 4 4 0 TMEM192 family NPV_P10 PF05531.7 CCM01149.1 - 2.6 8.3 17.5 0.47 10.7 0.1 5.9 5 1 0 6 6 6 0 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.5 CCM01150.1 - 2.9e-13 49.1 1.6 6.2e-13 48.1 1.1 1.6 1 0 0 1 1 1 1 DASH complex subunit Duo1 Ssl1 PF04056.9 CCM01152.1 - 3.7e-63 212.6 0.0 5.7e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 CCM01152.1 - 8.8e-08 32.4 0.0 2.7e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 CCM01152.1 - 0.47 9.6 7.1 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Transcription factor Tfb4 ADH_N PF08240.7 CCM01153.1 - 4.8e-27 93.8 1.0 8.1e-27 93.1 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM01153.1 - 1.3e-14 53.8 0.0 2.4e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM01153.1 - 9.7e-06 26.4 0.0 1.5e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCM01153.1 - 0.00011 21.4 0.2 0.00018 20.6 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CCM01153.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CCM01153.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ELFV_dehydrog PF00208.16 CCM01153.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.11 CCM01153.1 - 0.058 12.8 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_N PF08240.7 CCM01154.1 - 4.1e-27 94.0 3.3 7e-27 93.3 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM01154.1 - 5.2e-11 42.2 0.0 2.2e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCM01154.1 - 4.4e-05 22.7 0.0 7.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CCM01154.1 - 0.0058 16.4 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 CCM01154.1 - 0.022 14.2 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_C1_2 PF03051.10 CCM01155.1 - 1.7e-152 507.9 0.0 2.1e-152 507.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CCM01155.1 - 4.6e-06 26.6 0.0 0.083 12.7 0.0 2.4 2 1 0 2 2 2 2 Papain family cysteine protease RabGAP-TBC PF00566.13 CCM01156.1 - 3.6e-52 176.9 0.2 3.6e-52 176.9 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ABC1 PF03109.11 CCM01156.1 - 8e-32 109.7 0.0 1.8e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family CENP-Q PF13094.1 CCM01156.1 - 6 6.8 14.1 0.041 13.8 1.6 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PC4 PF02229.11 CCM01157.1 - 1.5e-14 52.9 0.6 1.5e-14 52.9 0.4 2.5 3 1 0 3 3 3 1 Transcriptional Coactivator p15 (PC4) HECT PF00632.20 CCM01158.1 - 1.6e-93 313.3 0.0 5.7e-93 311.5 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 CCM01158.1 - 1.9e-76 257.3 0.0 1.9e-76 257.3 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 CCM01158.1 - 3.8e-67 226.9 0.7 1.3e-66 225.1 0.5 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 CCM01158.1 - 2.2e-30 104.7 1.8 2.2e-30 104.7 1.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) UBA PF00627.26 CCM01158.1 - 1.7e-09 37.2 0.0 4.3e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain ADH_zinc_N PF00107.21 CCM01159.1 - 1.4e-09 37.5 0.4 2e-09 37.0 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 CCM01159.1 - 0.0037 17.2 2.0 0.0065 16.3 1.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase APG5 PF04106.7 CCM01160.1 - 6.1e-47 159.6 0.0 7.7e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 TP6A_N PF04406.9 CCM01161.1 - 0.048 13.3 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Type IIB DNA topoisomerase Git3 PF11710.3 CCM01162.1 - 5.6e-09 35.8 11.9 9.7e-09 35.0 8.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 CCM01162.1 - 0.00022 20.2 9.1 0.00033 19.6 6.3 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3_C PF11970.3 CCM01162.1 - 0.017 14.8 0.1 0.047 13.4 0.1 1.7 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term Prismane PF03063.15 CCM01162.1 - 0.26 9.6 0.1 0.41 8.9 0.0 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family CRAL_TRIO PF00650.15 CCM01164.1 - 6e-39 133.0 0.0 8.9e-39 132.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCM01164.1 - 9.1e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCM01164.1 - 0.0033 17.5 0.4 0.0079 16.3 0.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RRM_6 PF14259.1 CCM01168.1 - 4.5e-12 45.7 0.6 1.1e-06 28.5 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCM01168.1 - 1.7e-08 33.9 2.1 0.00052 19.5 0.0 4.4 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM01168.1 - 2.7e-05 23.9 0.2 0.046 13.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XPG_N PF00752.12 CCM01169.1 - 1.5e-29 102.2 0.0 3.1e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCM01169.1 - 6.7e-29 99.8 0.0 1.4e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CCM01169.1 - 1.7e-05 24.9 0.1 3.7e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF2201_N PF13203.1 CCM01169.1 - 4.6 6.3 6.6 0.44 9.6 1.1 1.9 3 0 0 3 3 3 0 Putative metallopeptidase domain Talin_middle PF09141.5 CCM01170.1 - 0.042 13.5 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Talin, middle domain Na_H_Exchanger PF00999.16 CCM01172.1 - 9.1e-56 189.0 29.0 1.1e-55 188.7 20.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Amino_oxidase PF01593.19 CCM01173.1 - 2.3e-16 59.9 0.0 6.8e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCM01173.1 - 1.8e-15 56.6 0.0 9.9e-15 54.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCM01173.1 - 0.00026 20.7 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 CCM01173.1 - 0.00077 18.4 0.1 0.002 17.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCM01173.1 - 0.0053 16.8 0.0 0.12 12.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM01173.1 - 0.072 13.5 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GPI-anchored PF10342.4 CCM01175.1 - 3.9e-08 33.6 0.1 5.2e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FKBP_C PF00254.23 CCM01177.1 - 9e-28 96.1 0.0 1.5e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sugar_tr PF00083.19 CCM01177.1 - 2.1e-18 66.1 17.8 6.8e-18 64.4 3.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCM01177.1 - 5e-17 61.6 44.1 2.8e-14 52.6 8.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily PRTase_1 PF11202.3 CCM01178.1 - 0.017 14.1 0.5 2.2 7.1 0.2 2.0 2 0 0 2 2 2 0 Phosphoribosyl transferase (PRTase) APG17 PF04108.7 CCM01178.1 - 0.056 12.2 3.7 0.13 10.9 2.6 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 RRF_GI PF12614.3 CCM01178.1 - 0.057 13.2 1.3 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Ribosome recycling factor PE PF00934.15 CCM01178.1 - 0.067 13.2 0.5 4.9 7.3 0.0 2.6 2 1 0 2 2 2 0 PE family FliG_C PF01706.11 CCM01178.1 - 0.11 12.4 1.4 0.72 9.8 0.2 2.6 1 1 2 3 3 3 0 FliG C-terminal domain Exonuc_VII_L PF02601.10 CCM01178.1 - 0.38 9.9 3.8 0.69 9.0 2.7 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2419 PF10343.4 CCM01179.1 - 1.1e-79 267.6 0.0 1.5e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) CCP_MauG PF03150.9 CCM01179.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Rft-1 PF04506.8 CCM01181.1 - 4.1e-93 312.6 15.0 5.9e-93 312.1 10.4 1.2 1 0 0 1 1 1 1 Rft protein SHMT PF00464.14 CCM01182.1 - 2.6e-170 566.0 0.0 3e-170 565.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CCM01182.1 - 0.00045 19.4 0.0 0.002 17.3 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCM01182.1 - 0.018 14.1 0.1 0.032 13.2 0.0 1.4 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.8 CCM01182.1 - 0.041 12.6 0.0 0.071 11.8 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Glyco_hydro_18 PF00704.23 CCM01183.1 - 8.6e-63 212.8 4.8 1.1e-62 212.4 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HET PF06985.6 CCM01184.1 - 2.5e-17 63.3 0.3 3e-13 50.1 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) COesterase PF00135.23 CCM01185.1 - 3.7e-62 210.7 0.0 2.1e-61 208.2 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM01185.1 - 0.0031 17.1 0.1 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 CCM01185.1 - 0.0075 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) COX14 PF14880.1 CCM01186.1 - 0.036 13.6 0.5 0.044 13.4 0.3 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Oxidored-like PF09791.4 CCM01187.1 - 2.9e-14 52.2 0.2 5.1e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Fumerase PF05681.9 CCM01187.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) JAB PF01398.16 CCM01188.1 - 7e-21 74.1 0.1 1.4e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CCM01188.1 - 0.0046 16.4 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Aldedh PF00171.17 CCM01190.1 - 2.4e-82 276.7 0.0 2.2e-78 263.6 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_S7 PF00177.16 CCM01191.1 - 5.4e-28 97.4 0.6 8.7e-28 96.7 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Mg_trans_NIPA PF05653.9 CCM01192.1 - 1e-105 353.0 14.7 1.3e-105 352.7 10.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CCM01192.1 - 2.1e-06 27.9 1.2 2.1e-06 27.9 0.8 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CCM01192.1 - 0.0016 18.4 5.5 0.0016 18.4 3.8 2.8 2 1 0 2 2 2 1 EamA-like transporter family Peptidase_M24 PF00557.19 CCM01193.1 - 6.5e-45 153.2 0.0 9.4e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCM01193.1 - 5.2e-24 85.2 0.0 6.9e-20 71.8 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain 4HBT PF03061.17 CCM01193.1 - 0.0095 16.0 0.1 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily F-box-like PF12937.2 CCM01194.1 - 3.2e-05 23.5 0.8 9.9e-05 21.9 0.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.8 CCM01194.1 - 0.0034 17.7 0.3 0.024 15.0 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich Repeat F-box PF00646.28 CCM01194.1 - 0.41 10.3 4.2 0.46 10.1 0.7 3.0 2 1 0 2 2 2 0 F-box domain adh_short PF00106.20 CCM01195.1 - 1.3e-33 116.2 1.6 1.9e-33 115.7 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM01195.1 - 3e-21 76.3 0.7 3.9e-21 75.9 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM01195.1 - 1.7e-12 47.4 1.4 2.9e-12 46.6 0.9 1.3 1 0 0 1 1 1 1 KR domain Apolipo_F PF15148.1 CCM01195.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein F Eno-Rase_NADH_b PF12242.3 CCM01195.1 - 1.1 9.0 4.8 1.2 8.9 0.2 2.8 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 CCM01196.1 - 4.6e-29 101.4 2.5 5.9e-29 101.1 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM01196.1 - 1.6e-16 60.8 0.0 2.7e-16 60.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM01196.1 - 2.4e-09 37.0 1.2 3.7e-09 36.5 0.9 1.3 1 0 0 1 1 1 1 KR domain HMG-CoA_red PF00368.13 CCM01197.1 - 1.4e-159 530.7 7.3 1.9e-159 530.3 5.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 CCM01197.1 - 2.1e-19 69.4 0.3 4.9e-19 68.2 0.2 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CCM01197.1 - 0.00032 18.7 0.1 0.00046 18.2 0.0 1.1 1 0 0 1 1 1 1 Patched family p450 PF00067.17 CCM01198.1 - 1.3e-64 218.5 0.0 7.6e-58 196.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Trm56 PF01994.11 CCM01198.1 - 0.082 12.6 0.0 33 4.2 0.0 3.2 3 0 0 3 3 3 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Ion_trans_2 PF07885.11 CCM01199.1 - 3.5e-29 100.3 34.5 9.7e-16 57.2 8.2 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 CCM01199.1 - 1.4 8.1 17.5 2.4 7.3 3.7 2.7 2 1 0 2 2 2 0 Ion transport protein Pribosyltran PF00156.22 CCM01200.1 - 1e-14 54.3 0.2 1.8e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 2-Hacid_dh_C PF02826.14 CCM01201.1 - 3.7e-40 136.9 0.0 6.4e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCM01201.1 - 4.5e-22 77.9 0.0 5.4e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 CCM01201.1 - 0.00052 20.3 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CCM01201.1 - 0.0017 18.2 0.0 0.0057 16.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase p450 PF00067.17 CCM01202.1 - 3.3e-64 217.1 0.0 4e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BioW PF03744.8 CCM01202.1 - 0.055 12.8 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 6-carboxyhexanoate--CoA ligase p450 PF00067.17 CCM01203.1 - 7.4e-70 235.7 0.0 9.3e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DER1 PF04511.10 CCM01204.1 - 4.7e-22 78.4 1.8 3.9e-21 75.4 1.3 2.0 1 1 0 1 1 1 1 Der1-like family BRCT PF00533.21 CCM01204.1 - 3.7e-09 36.6 0.0 6.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCM01204.1 - 4.9e-06 26.3 0.0 2.1e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 CCM01204.1 - 3.9e-05 23.7 0.1 9.4e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 CCM01204.1 - 0.0062 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) p450 PF00067.17 CCM01205.1 - 2e-58 198.0 0.0 2.3e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UCR_TM PF02921.9 CCM01205.1 - 0.11 12.7 0.6 0.28 11.4 0.4 1.7 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region p450 PF00067.17 CCM01206.1 - 2.3e-70 237.4 0.0 2.8e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1319 PF07028.6 CCM01206.1 - 0.0052 16.9 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) Transp_cyt_pur PF02133.10 CCM01207.1 - 2e-33 115.6 30.7 3.4e-32 111.5 21.3 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PIGA PF08288.7 CCM01208.1 - 1.5e-37 127.8 0.4 4.9e-37 126.1 0.3 1.9 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CCM01208.1 - 1e-24 86.8 0.0 2.1e-24 85.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCM01208.1 - 1.1e-14 54.5 1.3 2.3e-14 53.5 0.9 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CCM01208.1 - 3.1e-14 53.4 0.5 5.6e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CCM01208.1 - 1.3e-11 44.8 0.0 5.4e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CCM01208.1 - 0.0006 20.0 0.1 0.0054 16.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CCM01208.1 - 0.0049 16.7 0.1 0.0086 15.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.6 CCM01208.1 - 0.019 14.4 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Starch synthase catalytic domain Oxysterol_BP PF01237.13 CCM01209.1 - 4.6e-48 163.5 0.0 3.2e-35 121.2 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein AAA_33 PF13671.1 CCM01210.1 - 1.2e-22 80.3 0.0 7e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCM01210.1 - 5.8e-06 25.5 0.0 0.009 15.1 0.0 2.1 1 1 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 CCM01210.1 - 1e-05 25.8 0.0 0.016 15.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 CCM01210.1 - 1.2e-05 26.1 0.0 2.4e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 CCM01210.1 - 7.2e-05 22.7 0.0 0.0003 20.6 0.0 1.8 1 1 0 1 1 1 1 tRNA ligase kinase domain APS_kinase PF01583.15 CCM01210.1 - 0.00022 20.9 0.0 0.00088 18.9 0.0 1.8 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_29 PF13555.1 CCM01210.1 - 0.0045 16.4 0.1 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 CCM01210.1 - 0.0048 16.1 0.0 0.052 12.7 0.0 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 CCM01210.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCM01210.1 - 0.018 15.0 0.1 0.025 14.5 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CCM01210.1 - 0.028 14.7 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 CCM01210.1 - 0.034 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 6PF2K PF01591.13 CCM01210.1 - 0.068 12.2 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_PrkA PF08298.6 CCM01210.1 - 0.071 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain IstB_IS21 PF01695.12 CCM01210.1 - 0.081 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Thymidylate_kin PF02223.12 CCM01210.1 - 0.11 11.8 0.0 7.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Mg_chelatase PF01078.16 CCM01210.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SKI PF01202.17 CCM01210.1 - 0.15 11.9 0.0 4.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA_14 PF13173.1 CCM01210.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CCM01210.1 - 0.17 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2754 PF10953.3 CCM01211.1 - 0.022 14.8 0.2 0.05 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) TPR_11 PF13414.1 CCM01212.1 - 9.6e-22 76.4 3.1 1.4e-13 50.2 0.0 3.2 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 CCM01212.1 - 2.1e-14 52.1 1.8 3.3e-05 23.4 0.0 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCM01212.1 - 7.9e-13 48.1 4.0 9.4e-07 28.6 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM01212.1 - 9.8e-13 48.4 2.3 1.5e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCM01212.1 - 2.4e-12 45.8 1.4 3e-06 26.5 0.0 5.3 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCM01212.1 - 5.1e-12 44.9 0.2 0.0053 16.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCM01212.1 - 1.4e-09 37.7 3.2 0.0068 16.9 0.0 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCM01212.1 - 1.3e-08 35.0 0.9 9.5e-05 22.6 0.2 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CCM01212.1 - 9.2e-07 28.9 0.7 0.0049 16.9 0.1 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCM01212.1 - 3.2e-06 26.4 0.3 0.18 11.6 0.0 5.1 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCM01212.1 - 1.3e-05 24.9 1.2 0.012 15.4 0.8 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCM01212.1 - 1.3e-05 24.4 0.5 1.7e-05 24.0 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM01212.1 - 2.4e-05 23.7 3.1 0.12 12.1 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCM01212.1 - 6.7e-05 22.6 3.2 3.1 7.8 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCM01212.1 - 0.0013 18.8 0.7 0.13 12.4 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc5 PF12862.2 CCM01212.1 - 0.0037 17.0 0.2 0.0083 15.9 0.1 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 5 TPR_5 PF12688.2 CCM01212.1 - 0.0047 16.9 0.5 0.2 11.7 0.1 2.4 2 1 0 2 2 2 1 Tetratrico peptide repeat TPR_6 PF13174.1 CCM01212.1 - 0.0082 16.5 0.2 4.2 8.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat FAT PF02259.18 CCM01212.1 - 0.009 15.0 0.3 0.16 10.8 0.0 2.1 1 1 0 2 2 2 1 FAT domain Imm43 PF15602.1 CCM01212.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 1 0 1 1 1 0 Immunity protein 43 Exonuc_VII_S PF02609.11 CCM01212.1 - 0.18 11.6 1.7 2.7 7.8 0.1 2.8 3 1 0 3 3 3 0 Exonuclease VII small subunit TPR_4 PF07721.9 CCM01212.1 - 0.59 10.7 0.1 0.59 10.7 0.1 3.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Gly-zipper_Omp PF13488.1 CCM01213.1 - 7.6 6.2 11.3 1.3 8.7 5.3 1.6 2 0 0 2 2 2 0 Glycine zipper CorA PF01544.13 CCM01214.1 - 3e-12 46.1 1.8 4.5e-12 45.5 1.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1469 PF07332.6 CCM01214.1 - 0.15 11.8 2.7 2 8.1 1.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) AAA PF00004.24 CCM01215.1 - 2.3e-46 157.2 0.0 1.4e-42 145.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 CCM01215.1 - 1.4e-40 138.7 0.0 2.3e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCM01215.1 - 3e-34 118.6 0.0 2.8e-16 59.8 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.1 CCM01215.1 - 1.6e-18 66.2 0.5 6.1e-12 45.1 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 CCM01215.1 - 2.6e-16 59.7 0.0 1.9e-12 47.1 0.0 3.6 3 1 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CCM01215.1 - 7.6e-10 39.0 0.0 0.0018 18.4 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCM01215.1 - 1.9e-08 34.5 0.0 9.2e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CCM01215.1 - 2.2e-08 33.9 0.0 2.5e-05 24.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 CCM01215.1 - 1.9e-07 30.5 0.0 0.3 10.2 0.0 3.8 4 0 0 4 4 4 2 PhoH-like protein AAA_2 PF07724.9 CCM01215.1 - 2e-07 31.0 0.0 6e-07 29.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CCM01215.1 - 3.6e-06 27.8 1.0 0.00099 19.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 CCM01215.1 - 1.1e-05 24.8 0.0 0.036 13.3 0.0 2.8 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.12 CCM01215.1 - 3e-05 23.5 0.1 0.0033 16.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCM01215.1 - 3.9e-05 22.9 0.2 0.065 12.3 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CCM01215.1 - 6.1e-05 22.9 0.1 0.015 15.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 CCM01215.1 - 6.3e-05 22.1 0.0 0.00078 18.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CCM01215.1 - 9e-05 22.4 0.1 0.032 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCM01215.1 - 0.00019 21.3 0.0 0.021 14.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 CCM01215.1 - 0.00038 20.1 0.3 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCM01215.1 - 0.0015 17.9 0.0 0.29 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CCM01215.1 - 0.0018 17.8 0.0 4.7 6.6 0.0 4.1 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 CCM01215.1 - 0.002 17.9 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CCM01215.1 - 0.0022 18.1 0.0 0.31 11.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 CCM01215.1 - 0.0032 16.2 0.0 0.0077 14.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 CCM01215.1 - 0.0033 16.5 0.0 0.022 13.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin KaiC PF06745.8 CCM01215.1 - 0.0054 15.8 0.2 0.14 11.2 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 CCM01215.1 - 0.007 16.6 2.0 0.16 12.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 CCM01215.1 - 0.0078 15.6 0.0 0.29 10.5 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain AAA_3 PF07726.6 CCM01215.1 - 0.0092 15.5 0.0 0.034 13.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCM01215.1 - 0.0094 15.4 0.0 0.38 10.2 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CCM01215.1 - 0.012 15.3 0.0 4.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 CCM01215.1 - 0.012 16.0 1.2 0.92 9.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain Sigma54_activ_2 PF14532.1 CCM01215.1 - 0.016 15.2 0.0 0.77 9.8 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 CCM01215.1 - 0.02 13.8 0.0 3.1 6.6 0.0 2.6 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) DUF2072 PF09845.4 CCM01215.1 - 0.039 13.8 0.2 0.087 12.7 0.2 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NTPase_1 PF03266.10 CCM01215.1 - 0.079 12.6 0.0 4.9 6.8 0.0 2.7 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 CCM01215.1 - 0.08 12.5 0.0 2.2 7.8 0.0 2.9 3 0 0 3 3 3 0 NACHT domain DUF815 PF05673.8 CCM01215.1 - 0.11 11.3 0.0 0.28 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CCM01215.1 - 0.13 11.0 0.0 0.35 9.7 0.0 1.6 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 TFIID-18kDa PF02269.11 CCM01215.1 - 0.13 12.0 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit DivIC PF04977.10 CCM01215.1 - 0.17 11.3 1.8 0.53 9.8 1.2 1.8 1 0 0 1 1 1 0 Septum formation initiator UvrD_C PF13361.1 CCM01215.1 - 0.17 11.2 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 CCM01215.1 - 0.22 10.4 0.0 57 2.4 0.0 3.0 3 0 0 3 3 3 0 PIF1-like helicase NB-ARC PF00931.17 CCM01215.1 - 0.24 10.2 0.0 0.63 8.8 0.0 1.6 2 0 0 2 2 1 0 NB-ARC domain Peptidase_S10 PF00450.17 CCM01217.1 - 1.9e-92 310.6 5.9 2.3e-92 310.3 4.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3993 PF13158.1 CCM01217.1 - 0.069 12.9 1.5 3.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) Hira PF07569.6 CCM01218.1 - 3.1e-50 170.4 0.0 1.1e-49 168.5 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 CCM01218.1 - 2e-40 135.2 20.9 4.4e-09 35.8 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCM01218.1 - 0.084 12.3 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C2H2_jaz PF12171.3 CCM01219.1 - 3.6e-15 55.5 4.4 0.0011 19.0 0.0 3.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM01219.1 - 4.2e-13 48.9 1.2 0.002 18.2 0.0 3.3 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CCM01219.1 - 3.6e-08 33.1 6.6 0.17 12.3 1.0 3.4 2 1 1 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM01219.1 - 1.5e-05 25.0 7.4 0.071 13.4 0.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CCM01219.1 - 6.3e-05 23.0 0.9 0.0001 22.3 0.7 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Ecl1 PF12855.2 CCM01219.1 - 0.0057 15.9 0.9 0.79 9.0 0.0 2.5 2 0 0 2 2 2 1 Life-span regulatory factor zf-C2H2_6 PF13912.1 CCM01219.1 - 0.03 14.2 3.9 1.1 9.2 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 CCM01219.1 - 0.1 12.3 3.8 0.17 11.5 2.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HYPF PF07503.7 CCM01219.1 - 0.23 10.9 2.6 1 8.8 0.1 2.5 2 0 0 2 2 2 0 HypF finger zf-C2HC_2 PF13913.1 CCM01219.1 - 0.25 11.0 4.1 5.7 6.7 0.2 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2256 PF10013.4 CCM01219.1 - 0.3 10.8 3.2 2.3 8.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Vps39_2 PF10367.4 CCM01219.1 - 0.36 11.0 3.2 1.2 9.3 1.1 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 C1_2 PF03107.11 CCM01219.1 - 0.39 10.8 5.2 4.3 7.5 0.1 2.8 3 0 0 3 3 3 0 C1 domain zf-C3HC4_2 PF13923.1 CCM01219.1 - 0.95 9.5 4.7 10 6.2 0.2 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.1 CCM01219.1 - 1.3 9.4 10.3 10 6.5 0.1 3.5 4 0 0 4 4 3 0 Zinc-finger double domain zf-DBF PF07535.7 CCM01219.1 - 5 6.8 9.1 9.9 5.9 0.1 3.2 1 1 2 3 3 3 0 DBF zinc finger FYVE PF01363.16 CCM01219.1 - 6.1 6.8 7.2 3.8 7.4 2.8 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-PARP PF00645.13 CCM01220.1 - 7.1e-45 151.1 2.9 1.8e-23 82.6 0.3 2.6 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ribosomal_S26e PF01283.14 CCM01222.1 - 3.1e-25 88.6 0.5 3.7e-25 88.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 CCM01222.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) ADH_zinc_N_2 PF13602.1 CCM01223.1 - 2.4e-14 54.2 0.0 6.2e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCM01223.1 - 2.9e-13 49.4 0.0 4.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM01223.1 - 2.2e-11 43.4 0.1 1.3e-08 34.5 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain DAO PF01266.19 CCM01224.1 - 3.6e-25 88.6 1.6 2.1e-24 86.1 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCM01224.1 - 9.9e-07 27.9 0.1 1.5e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCM01224.1 - 5.2e-05 23.2 0.1 0.00049 20.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM01224.1 - 0.0017 18.3 3.3 0.002 18.0 0.7 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CCM01224.1 - 0.011 14.3 0.9 1.2 7.6 0.5 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 CCM01224.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 CCM01224.1 - 0.03 12.7 0.3 0.045 12.2 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 CCM01224.1 - 0.062 12.1 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CCM01224.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 CCM01224.1 - 0.21 12.0 2.5 0.36 11.2 1.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HLH PF00010.21 CCM01225.1 - 3.7e-11 42.5 0.2 1.2e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain AT_hook PF02178.14 CCM01225.1 - 2.2 8.2 9.5 1.9 8.4 4.8 2.4 2 0 0 2 2 2 0 AT hook motif DUF500 PF04366.7 CCM01226.1 - 9.4e-41 138.1 0.1 1.5e-40 137.4 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCM01226.1 - 3.8e-16 58.1 0.0 8.7e-16 57.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCM01226.1 - 3.5e-14 52.0 0.2 2.5e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CCM01226.1 - 2.2e-13 49.5 0.1 5.4e-13 48.3 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain DAO PF01266.19 CCM01227.1 - 1.2e-25 90.1 0.0 1.7e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCM01227.1 - 0.0019 18.1 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCM01227.1 - 0.0034 16.2 0.0 0.004 16.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCM01227.1 - 0.018 15.0 2.7 0.02 14.8 0.5 2.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 CCM01227.1 - 0.099 12.0 0.1 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 CCM01227.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 CCM01227.1 - 0.17 12.2 2.1 0.34 11.3 1.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NUDIX PF00293.23 CCM01228.1 - 2.1e-13 50.0 0.1 3.2e-13 49.4 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain DUF2046 PF09755.4 CCM01229.1 - 1.9e-10 40.1 4.8 1.9e-10 40.1 3.3 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) HSP20 PF00011.16 CCM01230.1 - 1.7e-05 24.6 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family FA_desaturase PF00487.19 CCM01231.1 - 1e-27 97.2 12.7 1.6e-27 96.5 8.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CCM01231.1 - 8.1e-19 66.5 0.3 1.4e-18 65.8 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) zf-C2H2_4 PF13894.1 CCM01232.1 - 0.045 14.0 1.5 0.14 12.5 1.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Shisa PF13908.1 CCM01232.1 - 5.4 7.1 5.4 14 5.8 3.8 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator adh_short PF00106.20 CCM01233.1 - 1.5e-32 112.8 3.8 1.9e-32 112.5 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM01233.1 - 1.8e-17 63.9 0.3 2.2e-17 63.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM01233.1 - 1.4e-11 44.4 1.9 1.9e-11 43.9 1.3 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CCM01234.1 - 2.4e-30 105.6 2.9 3e-30 105.3 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM01234.1 - 6.7e-19 68.6 0.2 8e-19 68.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM01234.1 - 9.1e-10 38.4 1.9 1.4e-09 37.8 1.3 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CCM01236.1 - 4.2e-28 98.3 3.2 5.6e-28 97.9 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM01236.1 - 2e-13 50.6 0.0 2.5e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM01236.1 - 4.3e-07 29.7 1.8 6.6e-07 29.1 1.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCM01236.1 - 0.21 11.5 1.3 0.4 10.6 0.3 1.8 2 0 0 2 2 2 0 NADH(P)-binding MFS_1 PF07690.11 CCM01237.1 - 9e-33 113.4 117.4 7.4e-20 70.9 35.6 3.7 2 2 2 4 4 4 4 Major Facilitator Superfamily p450 PF00067.17 CCM01238.1 - 7.9e-76 255.4 0.0 1.4e-75 254.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Ferric_reduct PF01794.14 CCM01239.1 - 4.9e-16 58.9 8.0 4.9e-16 58.9 5.6 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CCM01239.1 - 3e-13 49.5 0.0 5.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CCM01239.1 - 1e-08 35.2 0.0 1.4e-06 28.3 0.0 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 CCM01239.1 - 0.061 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain F-box-like PF12937.2 CCM01240.1 - 0.0007 19.2 0.1 0.002 17.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM01240.1 - 0.0093 15.6 0.1 0.0093 15.6 0.1 2.6 4 0 0 4 4 4 1 F-box domain Noc2 PF03715.8 CCM01240.1 - 0.033 13.0 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 Noc2p family Pkinase PF00069.20 CCM01241.1 - 1.8e-50 171.4 0.0 2.2e-27 95.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01241.1 - 4.5e-20 71.8 0.0 4.4e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCM01241.1 - 1.2e-12 47.4 0.0 8.6e-05 21.6 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 CCM01241.1 - 4 7.0 6.5 0.41 10.3 0.5 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family Glyco_hydro_cc PF11790.3 CCM01243.1 - 8.3e-63 212.0 6.6 9.9e-63 211.7 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Cellulase PF00150.13 CCM01243.1 - 0.00044 19.5 2.5 0.34 10.0 0.1 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF4598 PF15370.1 CCM01244.1 - 5.2e-10 39.6 0.6 1e-09 38.6 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) AF-4 PF05110.8 CCM01244.1 - 0.65 7.7 10.8 0.73 7.6 7.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein EPSP_synthase PF00275.15 CCM01245.1 - 1.5e-119 399.1 0.0 3.2e-119 398.1 0.0 1.5 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CCM01245.1 - 5.6e-100 333.5 0.1 1.4e-99 332.2 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CCM01245.1 - 5.5e-62 209.3 0.0 8.2e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CCM01245.1 - 6.4e-33 113.8 0.0 2.9e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 CCM01245.1 - 1.9e-26 91.9 0.0 6.6e-26 90.1 0.0 2.1 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CCM01245.1 - 1.4e-11 44.6 0.0 3.9e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CCM01245.1 - 1.5e-09 37.5 0.0 3.8e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CCM01245.1 - 9.1e-05 23.2 0.0 0.00025 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCM01245.1 - 0.037 13.9 0.0 0.59 9.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.1 CCM01245.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family Pyr_redox_2 PF07992.9 CCM01246.1 - 3.1e-27 95.7 0.0 4.2e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM01246.1 - 2e-11 44.1 0.1 6.4e-10 39.3 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM01246.1 - 0.0013 18.8 0.7 0.75 9.8 0.0 4.1 2 1 1 5 5 5 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CCM01246.1 - 0.02 15.1 0.2 0.31 11.3 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding ADH_N PF08240.7 CCM01247.1 - 3.9e-28 97.3 1.3 6.1e-28 96.7 0.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM01247.1 - 1.6e-18 66.4 0.2 3.2e-18 65.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_10 PF13237.1 CCM01247.1 - 0.08 12.7 0.3 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Spc97_Spc98 PF04130.8 CCM01248.1 - 1.4e-125 419.6 0.0 1.8e-125 419.3 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family S4 PF01479.20 CCM01249.1 - 3.4e-12 45.5 0.0 5.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CCM01249.1 - 0.0037 16.8 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 S4 domain ICMT PF04140.9 CCM01250.1 - 1.8e-12 47.2 0.8 5.7e-12 45.6 0.0 2.1 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM01250.1 - 2.2e-08 34.1 0.9 4.6e-08 33.1 0.2 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CCM01250.1 - 0.00035 19.2 0.0 0.00062 18.4 0.0 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UBX PF00789.15 CCM01252.1 - 3.3e-10 39.8 0.0 6.3e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CCM01252.1 - 6.9e-08 31.9 0.0 1.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.11 CCM01253.1 - 3.3e-11 42.4 0.1 7.4e-11 41.3 0.0 1.7 2 0 0 2 2 2 1 CUE domain Prenylcys_lyase PF07156.9 CCM01254.1 - 2.9e-38 131.7 0.0 8.4e-38 130.2 0.0 1.6 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 CCM01254.1 - 2.3e-09 37.1 0.0 5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CCM01254.1 - 3.8e-07 29.5 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 CCM01254.1 - 9.6e-06 24.7 0.5 0.00014 20.9 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM01254.1 - 0.00058 19.6 0.1 0.0022 17.7 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCM01254.1 - 0.017 14.9 0.1 0.056 13.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM01254.1 - 0.08 12.9 0.0 0.92 9.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM01254.1 - 0.086 11.9 0.2 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DUF3317 PF11779.3 CCM01255.1 - 5e-09 35.4 3.5 8.8e-09 34.6 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Epiglycanin_C PF14654.1 CCM01255.1 - 0.063 13.2 2.2 0.11 12.5 1.5 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF3317 PF11779.3 CCM01256.1 - 6.7e-11 41.4 2.6 1.3e-10 40.5 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF619 PF04768.8 CCM01257.1 - 1.7e-44 151.2 0.0 2.6e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CCM01257.1 - 1.8e-24 86.3 0.0 6.6e-24 84.5 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CCM01257.1 - 4.1e-19 69.0 0.0 8.2e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 CCM01257.1 - 0.00035 20.4 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Pam16 PF03656.8 CCM01257.1 - 0.19 11.5 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Pam16 Skp1_POZ PF03931.10 CCM01258.1 - 2.3e-06 27.6 0.0 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Myosin_head PF00063.16 CCM01260.1 - 3.8e-242 805.2 0.0 3.8e-242 805.2 0.0 3.0 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CCM01260.1 - 9.8e-35 119.5 239.4 1.6e-20 72.5 73.0 4.8 1 1 2 3 3 3 2 Myosin tail Myosin_N PF02736.14 CCM01260.1 - 1.5e-06 27.7 2.8 1.5e-06 27.7 2.0 2.0 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 CCM01260.1 - 0.037 14.1 0.1 0.037 14.1 0.0 6.7 5 2 1 6 6 6 0 AAA domain AAA_19 PF13245.1 CCM01260.1 - 0.046 13.4 0.0 0.21 11.3 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Abhydrolase_5 PF12695.2 CCM01261.1 - 2.3e-20 72.8 0.0 3.8e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM01261.1 - 3.9e-18 66.1 0.1 3e-16 59.9 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM01261.1 - 4.1e-09 36.3 0.0 5.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 CCM01261.1 - 2.6e-05 24.0 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 CCM01261.1 - 4.9e-05 21.9 0.2 0.0041 15.6 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 CCM01261.1 - 6.5e-05 22.4 0.0 0.14 11.5 0.0 2.9 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 CCM01261.1 - 0.0029 16.9 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 CCM01261.1 - 0.0087 15.5 0.0 0.7 9.2 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 CCM01261.1 - 0.15 11.4 0.0 0.65 9.4 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Metallophos PF00149.23 CCM01263.1 - 7.9e-41 139.6 0.7 1.1e-40 139.1 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.21 CCM01264.1 - 1.4e-26 92.5 1.3 1.5e-26 92.4 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM01264.1 - 2.5e-09 36.8 0.0 5.9e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CCM01264.1 - 0.027 15.3 0.0 0.053 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CCM01264.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pescadillo_N PF06732.6 CCM01264.1 - 0.066 12.4 0.2 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Pescadillo N-terminus NAD_binding_7 PF13241.1 CCM01264.1 - 0.099 12.9 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding EF-hand_7 PF13499.1 CCM01265.1 - 1e-11 44.8 0.0 1.5e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CCM01265.1 - 2.2e-11 42.6 0.5 5.2e-05 22.7 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CCM01265.1 - 1.3e-09 36.6 0.1 0.00039 19.5 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CCM01265.1 - 5.3e-07 29.1 0.0 7.7e-05 22.2 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.1 CCM01265.1 - 3.5e-06 26.8 0.0 0.029 14.2 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CCM01265.1 - 0.00087 18.5 0.1 1.3 8.4 0.0 2.6 2 0 0 2 2 2 2 EF hand UPF0154 PF03672.8 CCM01265.1 - 0.07 12.7 0.0 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SapB_1 PF05184.10 CCM01265.1 - 0.088 12.6 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 zf-C2H2_4 PF13894.1 CCM01266.1 - 0.00016 21.7 11.2 0.00023 21.2 1.1 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CCM01266.1 - 0.0011 18.5 5.9 0.0042 16.6 1.1 2.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 CCM01266.1 - 0.007 16.4 4.5 0.065 13.3 0.4 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CCM01266.1 - 0.0072 16.4 1.3 0.015 15.4 0.9 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 CCM01266.1 - 0.015 15.5 0.4 0.015 15.5 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger double domain DUF629 PF04780.7 CCM01266.1 - 0.031 12.7 2.3 0.051 12.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 CCM01266.1 - 0.21 12.0 10.5 0.16 12.3 2.0 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-BED PF02892.10 CCM01266.1 - 1.1 9.1 4.2 1.7 8.4 1.7 2.1 2 0 0 2 2 2 0 BED zinc finger zf-RING_3 PF14369.1 CCM01266.1 - 2.1 8.4 5.6 22 5.1 0.0 3.8 4 0 0 4 4 4 0 zinc-finger UQ_con PF00179.21 CCM01267.1 - 1.2e-47 160.8 0.0 1.3e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCM01267.1 - 4.7e-05 23.1 0.0 6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CCM01267.1 - 0.011 15.3 0.1 0.024 14.3 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CCM01267.1 - 0.064 13.1 0.1 0.068 13.0 0.1 1.4 1 1 0 1 1 1 0 RWD domain p450 PF00067.17 CCM01268.1 - 4.4e-71 239.7 0.0 5.5e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Srg PF02118.16 CCM01268.1 - 0.00033 20.1 5.9 0.00052 19.5 4.1 1.2 1 0 0 1 1 1 1 Srg family chemoreceptor UbiA PF01040.13 CCM01270.1 - 2.8e-26 92.2 16.6 3.6e-26 91.9 11.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family F-box-like PF12937.2 CCM01271.1 - 0.0056 16.3 0.1 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM01271.1 - 0.022 14.3 0.3 0.23 11.1 0.1 2.7 2 0 0 2 2 2 0 F-box domain DPPIV_N PF00930.16 CCM01272.1 - 1.2e-92 310.2 0.4 1.7e-92 309.7 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CCM01272.1 - 5.4e-46 156.5 2.4 8.4e-46 155.8 1.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCM01272.1 - 2.3e-07 30.6 0.2 4.6e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CCM01272.1 - 1.1e-05 24.9 0.3 2.2e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 CCM01272.1 - 0.00038 20.4 0.3 0.0015 18.4 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM01272.1 - 0.01 15.3 0.1 0.022 14.3 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PD40 PF07676.7 CCM01272.1 - 0.11 12.1 2.4 8.1 6.2 0.4 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SYS1 PF09801.4 CCM01273.1 - 6.2e-27 94.3 2.4 1.7e-19 70.2 0.9 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network BCS1_N PF08740.6 CCM01274.1 - 1.8e-28 99.4 1.4 1.8e-28 99.4 1.0 2.8 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 CCM01274.1 - 8.7e-11 42.1 0.0 2.1e-09 37.6 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BUD22 PF09073.5 CCM01274.1 - 0.002 17.3 39.9 0.0035 16.4 27.7 1.3 1 0 0 1 1 1 1 BUD22 DUF572 PF04502.8 CCM01274.1 - 0.23 10.6 29.0 0.48 9.5 20.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 CCM01274.1 - 2.6 6.9 19.4 5.5 5.9 13.5 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Menin PF05053.8 CCM01274.1 - 4.4 5.3 15.5 7.8 4.5 10.7 1.4 1 0 0 1 1 1 0 Menin Dynamin_M PF01031.15 CCM01275.1 - 2.5e-95 318.6 0.0 4.5e-95 317.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CCM01275.1 - 2.5e-53 180.3 0.0 4.3e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CCM01275.1 - 1.1e-30 105.3 2.8 1.7e-29 101.5 1.0 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCM01275.1 - 0.004 17.0 0.0 0.017 15.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Baculo_p74 PF04583.7 CCM01275.1 - 0.027 13.6 0.3 5.1 6.2 0.1 2.2 2 0 0 2 2 2 0 Baculoviridae p74 conserved region AAA_16 PF13191.1 CCM01275.1 - 0.029 14.3 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Condensin2nSMC PF12422.3 CCM01275.1 - 0.053 13.2 0.1 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Miro PF08477.8 CCM01275.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein YccV-like PF08755.6 CCM01275.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like Mt_ATP-synt_B PF05405.9 CCM01276.1 - 4.5e-44 149.7 10.3 5.4e-44 149.5 7.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Cullin_binding PF03556.10 CCM01276.1 - 0.025 14.7 0.4 0.038 14.1 0.3 1.3 1 0 0 1 1 1 0 Cullin binding CS PF04969.11 CCM01278.1 - 8.4e-09 35.8 0.0 1.7e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 CS domain Sporozoite_P67 PF05642.6 CCM01278.1 - 0.047 11.5 0.1 0.044 11.6 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATP11 PF06644.6 CCM01280.1 - 1.4e-62 211.6 0.0 1.7e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein WD40 PF00400.27 CCM01281.1 - 2.9e-46 153.7 2.8 2.2e-09 36.8 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCM01281.1 - 3.7e-07 28.6 0.2 0.0051 14.9 0.0 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 APG6 PF04111.7 CCM01281.1 - 1.1 8.2 4.1 1.8 7.5 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CCM01281.1 - 2.1 7.9 5.3 3.4 7.2 3.7 1.2 1 0 0 1 1 1 0 IncA protein PseudoU_synth_2 PF00849.17 CCM01282.1 - 2.2e-27 95.8 0.0 3.8e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase FAD_binding_3 PF01494.14 CCM01284.1 - 2.6e-76 257.0 0.0 3.3e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCM01284.1 - 3.3e-06 27.0 0.1 1.3e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCM01284.1 - 5.6e-06 25.6 0.3 6.8e-05 22.0 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 CCM01284.1 - 2e-05 24.5 0.0 0.00025 20.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM01284.1 - 2.2e-05 23.0 0.5 0.00049 18.6 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 CCM01284.1 - 2.5e-05 24.6 0.0 0.00076 19.8 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCM01284.1 - 3.7e-05 22.7 1.0 7.8e-05 21.6 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CCM01284.1 - 0.0005 19.0 1.1 0.0012 17.7 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM01284.1 - 0.0024 16.8 0.1 0.0046 15.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CCM01284.1 - 0.0059 16.7 0.2 0.012 15.6 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCM01284.1 - 0.016 14.2 0.2 0.045 12.8 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM01284.1 - 0.021 14.6 0.2 0.048 13.4 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 CCM01284.1 - 0.022 13.6 0.1 0.037 12.8 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 CCM01284.1 - 0.023 14.4 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 CCM01284.1 - 0.027 13.1 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 CCM01284.1 - 0.096 12.3 0.0 0.25 10.9 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 CCM01285.1 - 1.7e-76 257.5 0.0 2.5e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 CCM01285.1 - 2e-06 26.9 0.5 0.0022 16.9 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.12 CCM01285.1 - 0.00033 19.8 0.1 0.0015 17.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 CCM01285.1 - 0.00045 20.5 0.1 0.95 9.9 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM01285.1 - 0.00083 18.3 0.1 0.072 11.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCM01285.1 - 0.0013 18.6 0.1 0.0038 17.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM01285.1 - 0.0089 16.0 0.2 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCM01285.1 - 0.011 14.1 0.1 1 7.7 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 CCM01285.1 - 0.036 13.1 0.3 0.4 9.6 0.2 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCM01285.1 - 0.052 13.6 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM01285.1 - 0.15 10.9 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 CCM01286.1 - 4.1e-80 269.5 0.0 5.1e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 CCM01286.1 - 2e-06 26.9 0.3 0.00015 20.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CCM01286.1 - 2.5e-06 27.8 0.1 0.011 16.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM01286.1 - 3.8e-05 22.8 0.1 0.0001 21.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 CCM01286.1 - 0.00023 21.0 0.1 0.00086 19.2 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM01286.1 - 0.00026 19.5 0.3 0.025 13.0 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 CCM01286.1 - 0.00034 20.5 0.2 0.001 19.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCM01286.1 - 0.00076 18.4 0.2 0.0033 16.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCM01286.1 - 0.0055 16.7 0.0 0.076 13.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCM01286.1 - 0.0058 15.7 0.4 0.053 12.6 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 CCM01286.1 - 0.022 14.5 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 CCM01286.1 - 0.042 12.7 0.1 0.081 11.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 CCM01286.1 - 0.087 13.0 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.11 CCM01286.1 - 0.12 11.8 0.1 0.37 10.2 0.1 1.9 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CPSase_L_chain PF00289.17 CCM01286.1 - 0.13 12.3 0.0 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain FAD_binding_3 PF01494.14 CCM01287.1 - 1.7e-60 204.9 0.0 9.4e-60 202.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CCM01287.1 - 4.1e-05 23.8 0.1 0.014 15.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM01287.1 - 5.2e-05 22.4 0.0 9.2e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 CCM01287.1 - 0.00012 21.1 0.2 0.00019 20.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCM01287.1 - 0.00041 20.2 0.1 0.003 17.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM01287.1 - 0.00045 20.1 0.2 0.0014 18.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCM01287.1 - 0.0018 17.2 0.1 0.0039 16.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCM01287.1 - 0.016 13.7 0.1 0.038 12.4 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 CCM01287.1 - 0.056 13.1 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 CCM01287.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM01287.1 - 0.079 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 CCM01287.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 CCM01288.1 - 3.6e-71 240.0 0.0 5.9e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCM01288.1 - 4.8e-07 29.8 0.0 0.00027 20.8 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM01288.1 - 6e-07 28.6 0.9 0.00083 18.3 0.2 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCM01288.1 - 9.1e-06 25.9 1.2 0.0045 17.3 0.1 3.1 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM01288.1 - 9.1e-05 21.6 0.4 0.00026 20.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 CCM01288.1 - 0.00012 22.0 0.1 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCM01288.1 - 0.00024 20.0 2.5 0.0011 17.9 0.2 2.5 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.9 CCM01288.1 - 0.0022 16.5 0.3 0.032 12.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 CCM01288.1 - 0.007 16.4 0.1 0.017 15.1 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM01288.1 - 0.0074 15.2 0.6 0.029 13.2 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 CCM01288.1 - 0.0099 14.5 0.2 0.023 13.3 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.13 CCM01288.1 - 0.016 15.2 0.1 0.068 13.1 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 CCM01288.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 CCM01288.1 - 0.023 14.4 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CCM01288.1 - 0.066 12.8 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF869 PF05911.6 CCM01289.1 - 0.005 15.1 0.5 0.007 14.6 0.4 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) HAUS-augmin3 PF14932.1 CCM01289.1 - 0.016 14.4 0.1 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 HWE_HK PF07536.9 CCM01289.1 - 0.047 14.1 4.3 3 8.3 0.2 2.6 1 1 1 2 2 2 0 HWE histidine kinase STE3 PF02076.10 CCM01290.1 - 2.4e-80 269.6 21.8 2.9e-80 269.4 15.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor NAD_binding_10 PF13460.1 CCM01291.1 - 1.9e-26 93.2 0.2 2.2e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCM01291.1 - 1.6e-09 37.3 0.0 2.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CCM01291.1 - 2.5e-07 30.3 0.0 5.9e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCM01291.1 - 0.00021 21.5 0.0 0.00038 20.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 CCM01291.1 - 0.00033 20.6 0.0 0.0008 19.3 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.14 CCM01291.1 - 0.00074 18.3 0.0 0.0014 17.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ApbE PF02424.10 CCM01291.1 - 0.056 12.7 0.6 0.42 9.8 0.2 2.0 1 1 1 2 2 2 0 ApbE family VWA_2 PF13519.1 CCM01291.1 - 0.073 13.1 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 von Willebrand factor type A domain KR PF08659.5 CCM01291.1 - 0.1 12.2 0.1 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 KR domain Cellulase PF00150.13 CCM01292.1 - 2e-17 63.3 0.2 2.7e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Imm21 PF15569.1 CCM01293.1 - 0.033 13.9 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 21 BPL_LplA_LipB PF03099.14 CCM01294.1 - 6.3e-10 39.1 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Thiolase_N PF00108.18 CCM01295.1 - 3.6e-07 29.4 0.0 7.3e-06 25.1 0.0 2.5 2 1 1 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCM01295.1 - 8e-06 25.2 0.0 0.00011 21.6 0.0 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCM01295.1 - 3.6e-05 23.3 0.7 0.0011 18.5 0.4 2.8 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CCM01295.1 - 0.00015 21.3 0.1 0.017 14.7 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Flavi_NS2B PF01002.14 CCM01297.1 - 0.034 13.7 0.2 0.084 12.4 0.1 1.6 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B EphA2_TM PF14575.1 CCM01297.1 - 0.082 13.3 0.1 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CobD_Cbib PF03186.8 CCM01298.1 - 0.021 13.9 0.2 0.024 13.7 0.2 1.1 1 0 0 1 1 1 0 CobD/Cbib protein p450 PF00067.17 CCM01299.1 - 1.2e-56 192.2 0.0 1.5e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Utp12 PF04003.7 CCM01300.1 - 1.5e-13 50.6 0.6 7.9e-13 48.2 0.4 1.9 1 1 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.5 CCM01300.1 - 0.067 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 UTP15 C terminal VARLMGL PF14383.1 CCM01300.1 - 0.076 12.1 0.3 3.9 6.7 0.0 3.0 2 0 0 2 2 2 0 DUF761-associated sequence motif Daxx PF03344.10 CCM01300.1 - 2.4 6.5 28.5 0.17 10.3 16.5 1.4 2 0 0 2 2 2 0 Daxx Family Pkinase PF00069.20 CCM01302.1 - 8.7e-73 244.6 0.0 1.5e-72 243.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01302.1 - 3e-34 118.2 0.0 6.1e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM01302.1 - 0.0011 17.9 2.8 0.0026 16.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCM01302.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family HEAT_EZ PF13513.1 CCM01302.1 - 0.37 11.3 0.1 0.37 11.3 0.1 2.0 2 0 0 2 2 2 0 HEAT-like repeat HATPase_c PF02518.21 CCM01303.1 - 1.3e-26 92.4 0.1 3.2e-26 91.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fapy_DNA_glyco PF01149.19 CCM01303.1 - 7.7e-17 61.7 0.1 2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain HisKA PF00512.20 CCM01303.1 - 1.2e-16 60.4 0.7 7.1e-16 57.9 0.0 2.9 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 CCM01303.1 - 3.9e-16 59.5 1.7 3.7e-15 56.3 0.8 2.5 2 0 0 2 2 2 1 AAA ATPase domain Pkinase PF00069.20 CCM01303.1 - 1.1e-09 37.8 0.0 2.4e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain H2TH PF06831.9 CCM01303.1 - 1.2e-07 31.3 0.0 6.2e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain Response_reg PF00072.19 CCM01303.1 - 7.8e-07 29.0 0.1 0.002 18.1 0.1 2.9 2 0 0 2 2 2 2 Response regulator receiver domain Pkinase_Tyr PF07714.12 CCM01303.1 - 8.2e-07 28.3 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_22 PF13401.1 CCM01303.1 - 0.00035 20.7 0.0 0.0031 17.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF3369 PF11849.3 CCM01303.1 - 0.028 14.3 0.0 0.09 12.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) HATPase_c_3 PF13589.1 CCM01303.1 - 0.054 13.1 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3293 PF11697.3 CCM01303.1 - 0.092 12.8 0.1 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) Zeta_toxin PF06414.7 CCM01303.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DEAD PF00270.24 CCM01304.1 - 1e-36 125.9 0.6 1.9e-36 125.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM01304.1 - 4.7e-25 87.2 0.0 5.5e-24 83.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM01304.1 - 5.2e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.22 CCM01305.1 - 2.4e-54 181.0 0.6 1.6e-21 75.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 CCM01305.1 - 7.1e-40 136.2 0.1 1.3e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM01305.1 - 1.7e-23 82.2 0.1 3.6e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM01305.1 - 2.5e-05 24.1 0.0 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCM01305.1 - 0.00048 19.0 0.0 0.00077 18.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 CCM01305.1 - 0.042 12.2 0.8 0.36 9.1 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1253) HMG_box PF00505.14 CCM01306.1 - 2e-13 50.3 0.3 3.7e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM01306.1 - 1.1e-06 28.8 0.1 2.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain PolyA_pol PF01743.15 CCM01307.1 - 1.3e-24 86.8 0.0 2.1e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CCM01307.1 - 2e-06 27.2 0.0 4.8e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 CCM01307.1 - 0.00091 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Arm PF00514.18 CCM01308.1 - 1.5e-66 218.0 33.9 3.7e-13 48.7 0.1 11.6 10 2 2 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCM01308.1 - 6.5e-25 87.2 12.3 1e-06 28.9 0.7 7.6 2 2 3 6 6 6 6 HEAT repeats HEAT PF02985.17 CCM01308.1 - 2.9e-17 61.1 18.8 0.012 15.5 0.0 9.8 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 CCM01308.1 - 1e-14 54.5 14.4 0.019 15.4 0.4 7.9 6 2 3 9 9 9 5 HEAT-like repeat Arm_2 PF04826.8 CCM01308.1 - 4.7e-12 45.5 12.9 0.00075 18.6 0.7 3.5 1 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 CCM01308.1 - 1.1e-10 40.5 13.2 2.9e-08 32.4 0.1 2.4 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.7 CCM01308.1 - 1.5e-08 33.0 4.7 2.3e-08 32.4 3.3 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 CCM01308.1 - 5.2e-07 29.0 10.9 0.0052 15.9 0.1 4.4 2 1 2 4 4 4 3 V-ATPase subunit H V-ATPase_H_C PF11698.3 CCM01308.1 - 0.0014 18.5 5.9 9.3 6.1 0.1 4.6 2 1 3 5 5 5 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 CCM01308.1 - 0.0034 17.7 0.2 0.8 10.1 0.1 3.2 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region DUF2454 PF10521.4 CCM01308.1 - 0.011 14.7 1.4 0.19 10.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) HEAT_PBS PF03130.11 CCM01308.1 - 0.042 14.3 14.6 9.8 6.9 0.3 7.6 9 0 0 9 9 8 0 PBS lyase HEAT-like repeat DUF3361 PF11841.3 CCM01308.1 - 0.11 12.2 7.0 0.78 9.4 0.6 3.8 2 2 0 3 3 3 0 Domain of unknown function (DUF3361) Glyco_hydro_16 PF00722.16 CCM01309.1 - 3.6e-07 29.6 0.1 1.3e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SprT-like PF10263.4 CCM01310.1 - 6.5e-42 142.8 1.8 1e-41 142.1 1.3 1.3 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 CCM01310.1 - 0.21 11.5 6.6 0.11 12.4 2.5 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_S14 PF00253.16 CCM01311.1 - 1.5e-17 62.7 3.5 1.6e-17 62.6 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Toxin_17 PF08086.6 CCM01311.1 - 1.7 8.8 4.2 0.83 9.7 0.3 2.0 1 1 1 2 2 2 0 Ergtoxin family Glyco_hydro_16 PF00722.16 CCM01312.1 - 9.2e-08 31.5 0.0 2.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Acatn PF13000.2 CCM01313.1 - 5.2e-92 309.1 16.8 4e-68 230.2 5.5 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DoxX_2 PF13564.1 CCM01313.1 - 0.31 11.0 4.7 0.32 10.9 0.1 2.8 2 1 0 2 2 2 0 DoxX-like family GYF PF02213.11 CCM01314.1 - 9.4e-16 57.1 0.1 2.1e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 GYF domain Atg14 PF10186.4 CCM01316.1 - 3.2e-14 52.5 0.0 5.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 PUF PF00806.14 CCM01317.1 - 1.6e-55 181.5 10.5 1.3e-07 30.7 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 CCM01317.1 - 0.021 15.1 0.5 0.78 10.0 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function DUF260 7tm_7 PF08395.7 CCM01317.1 - 0.11 11.4 3.1 4.5 6.1 1.0 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor Pkinase PF00069.20 CCM01318.1 - 3e-73 246.1 0.0 6.6e-70 235.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01318.1 - 5.7e-37 127.2 0.0 7.1e-33 113.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CCM01318.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CCM01318.1 - 0.0015 17.5 0.1 0.0035 16.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCM01318.1 - 0.0044 16.0 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CCM01318.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 CCM01318.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase ICMT PF04140.9 CCM01320.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM01320.1 - 0.017 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipid methyltransferase Bromodomain PF00439.20 CCM01322.1 - 4.9e-21 74.4 0.5 1.3e-20 73.1 0.3 1.8 1 0 0 1 1 1 1 Bromodomain EPL1 PF10513.4 CCM01322.1 - 2.1e-20 73.5 1.6 2.1e-20 73.5 1.1 2.5 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.1 CCM01322.1 - 4.8e-17 61.9 0.7 3.7e-15 55.8 0.0 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.1 CCM01322.1 - 1.8e-15 55.9 2.7 3.4e-15 55.0 1.9 1.5 1 0 0 1 1 1 1 PHD-finger PWWP PF00855.12 CCM01322.1 - 2.8e-14 53.0 0.2 6.3e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 CCM01322.1 - 1.3e-09 37.5 5.8 1.3e-09 37.5 4.0 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 CCM01322.1 - 2.5e-05 24.3 1.6 0.00093 19.2 0.0 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain C1_1 PF00130.17 CCM01322.1 - 0.0037 16.9 0.3 0.0097 15.6 0.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 CCM01322.1 - 0.0051 16.1 1.0 0.0051 16.1 0.7 1.7 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.11 CCM01322.1 - 0.08 12.8 1.4 0.17 11.7 0.3 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 CCM01322.1 - 0.18 11.5 2.2 0.44 10.3 1.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF4206 PF13901.1 CCM01322.1 - 0.36 10.3 7.9 0.6 9.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) zf-RanBP PF00641.13 CCM01322.1 - 0.41 9.7 2.3 0.59 9.2 0.2 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Actin PF00022.14 CCM01323.1 - 1.3e-104 349.7 0.0 1.6e-104 349.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCM01323.1 - 0.0041 15.7 0.0 0.0098 14.5 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein RNA_pol_Rbc25 PF08292.7 CCM01324.1 - 1.3e-31 109.3 0.0 1.6e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Mito_carr PF00153.22 CCM01325.1 - 1.2e-68 226.8 2.9 7.1e-24 83.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SKG6 PF08693.5 CCM01326.1 - 0.0013 17.9 0.7 0.0035 16.6 0.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.6 CCM01326.1 - 8.6 5.4 7.6 13 4.8 5.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Herpes_gE PF02480.11 CCM01327.1 - 0.12 10.6 0.2 0.15 10.2 0.2 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E FUSC_2 PF13515.1 CCM01327.1 - 0.2 11.5 1.9 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Phos_pyr_kin PF08543.7 CCM01328.1 - 8.9e-09 34.8 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CCM01328.1 - 6.4e-06 25.5 0.1 9e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase UbiA PF01040.13 CCM01329.1 - 9.2e-24 84.0 6.0 3e-23 82.3 4.2 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family START PF01852.14 CCM01330.1 - 7.8e-22 77.6 0.3 3.6e-08 32.9 0.0 4.1 3 2 0 3 3 3 3 START domain LisH PF08513.6 CCM01331.1 - 4.1e-06 26.3 0.1 6.8e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 LisH LRR_4 PF12799.2 CCM01332.1 - 0.00038 19.9 0.0 0.018 14.6 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CCM01332.1 - 0.0062 16.2 0.0 0.025 14.2 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 CCM01332.1 - 0.024 14.3 1.7 0.12 12.1 0.2 2.8 2 1 1 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 CCM01332.1 - 0.2 12.0 4.3 6.7 7.3 0.1 3.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 CCM01332.1 - 0.46 10.7 3.2 6.8 7.1 0.2 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat Peptidase_M20 PF01546.23 CCM01333.1 - 1.1e-09 38.0 0.6 2.1e-09 37.1 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCM01333.1 - 1.8e-08 34.0 0.0 3.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain HATPase_c PF02518.21 CCM01334.1 - 3.7e-23 81.3 0.0 1.4e-22 79.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCM01334.1 - 8e-16 58.0 0.0 1.1e-14 54.3 0.0 2.7 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CCM01334.1 - 0.0069 16.3 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 CCM01334.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHD PF00628.24 CCM01335.1 - 6.3e-11 41.7 41.7 1.7e-08 33.9 6.2 4.9 4 0 0 4 4 4 2 PHD-finger BAH PF01426.13 CCM01335.1 - 2.4e-10 40.1 0.0 4.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.1 CCM01335.1 - 0.0081 15.4 3.5 0.0081 15.4 2.4 5.3 5 1 0 5 5 5 2 PHD-finger AT_hook PF02178.14 CCM01335.1 - 0.11 12.2 2.9 0.28 10.9 2.0 1.7 1 0 0 1 1 1 0 AT hook motif GATA PF00320.22 CCM01335.1 - 0.64 9.4 14.8 0.05 12.9 5.2 3.0 3 0 0 3 3 3 0 GATA zinc finger UCH PF00443.24 CCM01336.1 - 7.9e-73 244.8 0.0 1.1e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM01336.1 - 1.5e-23 83.6 0.0 2.6e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CCM01336.1 - 0.0024 18.1 0.0 0.0056 17.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.15 CCM01336.1 - 0.016 14.7 0.6 0.035 13.6 0.4 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FAD_binding_3 PF01494.14 CCM01337.1 - 3.1e-83 279.7 0.0 7e-83 278.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 CCM01337.1 - 6.2e-30 104.0 0.0 1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 CCM01337.1 - 2.3e-06 26.7 1.2 6.3e-06 25.2 0.6 1.9 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.9 CCM01337.1 - 3.8e-06 25.6 0.4 5.8e-06 25.0 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 CCM01337.1 - 2.1e-05 24.4 0.1 6.5e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCM01337.1 - 3.9e-05 22.8 0.1 7.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CCM01337.1 - 0.00016 21.6 0.1 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM01337.1 - 0.00027 19.9 0.2 0.00077 18.4 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCM01337.1 - 0.00027 21.2 0.1 0.0014 19.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM01337.1 - 0.00075 18.5 0.7 0.0011 17.9 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 CCM01337.1 - 0.0017 17.8 0.1 0.0035 16.7 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 CCM01337.1 - 0.0033 17.5 0.1 0.007 16.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCM01337.1 - 0.004 16.0 0.4 0.007 15.2 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_10 PF13460.1 CCM01337.1 - 0.0089 16.0 0.1 0.023 14.6 0.0 1.9 2 0 0 2 2 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 CCM01337.1 - 0.0094 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 CCM01337.1 - 0.01 14.9 0.1 0.014 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 CCM01337.1 - 0.017 14.8 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 CCM01337.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF2199 PF09965.4 CCM01337.1 - 0.043 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) AlaDh_PNT_C PF01262.16 CCM01337.1 - 0.046 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 CCM01337.1 - 0.053 13.2 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.1 CCM01337.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Trp_halogenase PF04820.9 CCM01337.1 - 0.1 11.2 0.3 0.2 10.2 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Peptidase_M20 PF01546.23 CCM01338.1 - 5.9e-31 107.4 0.0 8.6e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCM01338.1 - 4.1e-05 23.2 0.0 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 CCM01339.1 - 2.1e-24 86.0 0.0 3.4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCM01339.1 - 8.8e-14 51.2 0.0 1.6e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Pyridoxal_deC PF00282.14 CCM01340.1 - 1.7e-21 76.0 0.0 8.6e-12 44.1 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain YqzE PF14038.1 CCM01341.1 - 2.7 7.7 7.0 5.3 6.8 1.1 2.5 2 0 0 2 2 2 0 YqzE-like protein DUF605 PF04652.11 CCM01341.1 - 6.4 6.0 15.3 8.9 5.5 10.6 1.3 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 CCM01342.1 - 1.7e-05 24.5 0.4 0.0014 18.3 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat SET PF00856.23 CCM01343.1 - 9e-12 45.5 0.5 2e-11 44.4 0.2 1.7 2 0 0 2 2 2 1 SET domain Exo70 PF03081.10 CCM01344.1 - 2.6e-48 164.7 0.2 4.1e-48 164.0 0.1 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit CBFD_NFYB_HMF PF00808.18 CCM01344.1 - 1.8e-28 98.3 0.1 9.8e-26 89.6 0.1 3.1 3 0 0 3 3 3 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCM01344.1 - 2.1e-06 27.7 0.0 9.1e-06 25.7 0.0 2.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 F-box-like PF12937.2 CCM01344.1 - 0.0038 16.9 0.2 0.0099 15.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like TFIID-18kDa PF02269.11 CCM01344.1 - 0.041 13.7 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Methyltransf_11 PF08241.7 CCM01345.1 - 3.3e-05 24.3 0.0 5.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM01345.1 - 0.018 15.4 0.0 0.043 14.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 CCM01345.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CCM01345.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.11 CCM01346.1 - 4.5e-13 48.6 40.1 4.5e-13 48.6 27.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 CCM01346.1 - 1e-12 47.8 7.7 1e-12 47.8 5.4 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2286 PF10051.4 CCM01346.1 - 0.033 13.8 0.1 0.055 13.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) DUF4131 PF13567.1 CCM01346.1 - 0.064 12.6 14.7 0.35 10.2 3.0 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) RNA_lig_T4_1 PF09511.5 CCM01347.1 - 5.4e-76 254.9 0.0 8.4e-76 254.3 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 CCM01347.1 - 4.9e-28 98.1 0.2 9.2e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 CCM01347.1 - 1.2e-19 70.5 0.0 4.1e-19 68.8 0.0 1.9 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_17 PF13207.1 CCM01347.1 - 0.003 18.3 0.1 0.037 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 CCM01347.1 - 0.008 15.4 0.1 0.018 14.2 0.1 1.6 1 1 1 2 2 2 1 Chromatin associated protein KTI12 2_5_RNA_ligase2 PF13563.1 CCM01347.1 - 0.009 15.7 0.1 0.22 11.2 0.0 2.9 3 0 0 3 3 3 1 2'-5' RNA ligase superfamily Mis12 PF05859.7 CCM01349.1 - 1.7e-26 92.7 0.0 4.2e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Mis12 protein Ribosomal_L14e PF01929.12 CCM01349.1 - 1.5e-24 86.1 0.4 3.8e-24 84.8 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CCM01349.1 - 1.8e-05 24.2 0.3 3e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 KOW motif KRAP_IP3R_bind PF14722.1 CCM01349.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Lzipper-MIP1 PF14389.1 CCM01349.1 - 0.15 12.1 4.4 0.13 12.4 1.3 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ATP_bind_1 PF03029.12 CCM01350.1 - 1.3e-74 250.7 0.0 1.5e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 CCM01350.1 - 0.084 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CCM01350.1 - 0.14 12.0 0.6 1.4 8.8 0.4 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 CCM01350.1 - 3.2 8.5 7.6 1.1 10.0 2.1 2.4 2 1 0 2 2 2 0 AAA domain Cellulase PF00150.13 CCM01351.1 - 0.053 12.7 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) CNH PF00780.17 CCM01353.1 - 2.2e-76 256.9 0.0 3.4e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CCM01353.1 - 7e-39 132.8 0.6 1.5e-38 131.8 0.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 CCM01353.1 - 1.5e-38 132.4 0.0 2.4e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 CCM01353.1 - 2.8e-12 46.1 0.1 6.5e-12 45.0 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_10 PF15411.1 CCM01353.1 - 0.26 11.4 0.8 0.61 10.2 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Sec1 PF00995.18 CCM01354.1 - 4.1e-138 461.5 0.0 5.2e-138 461.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Carn_acyltransf PF00755.15 CCM01355.1 - 2.6e-136 455.1 0.0 2.9e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase F-box-like PF12937.2 CCM01356.1 - 0.012 15.2 1.8 0.032 13.9 1.3 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 CCM01356.1 - 0.38 10.4 2.5 1.7 8.4 1.8 2.1 1 1 0 1 1 1 0 F-box domain Ribosomal_L5_C PF00673.16 CCM01357.1 - 8.3e-22 76.7 0.0 1.7e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCM01357.1 - 1.4e-19 69.6 0.0 3.5e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L5 LRR_8 PF13855.1 CCM01357.1 - 0.071 12.8 0.4 8.3 6.2 0.1 2.9 2 0 0 2 2 2 0 Leucine rich repeat EI24 PF07264.6 CCM01358.1 - 1.6e-07 31.0 15.2 4.3e-07 29.5 7.6 2.6 1 1 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) UDPGT PF00201.13 CCM01359.1 - 1.2e-13 50.4 0.0 1.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ADIP PF11559.3 CCM01360.1 - 2.5e-20 72.9 8.4 2.5e-20 72.9 5.8 3.4 4 0 0 4 4 4 2 Afadin- and alpha -actinin-Binding DUF4407 PF14362.1 CCM01360.1 - 0.16 10.8 18.6 0.025 13.5 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AKNA PF12443.3 CCM01360.1 - 0.27 11.2 5.8 0.14 12.1 0.2 3.0 2 1 0 2 2 2 0 AT-hook-containing transcription factor Reo_sigmaC PF04582.7 CCM01360.1 - 0.31 10.1 7.8 1.3 8.1 2.2 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 CCM01360.1 - 0.43 9.5 21.6 1 8.3 4.7 2.5 2 1 1 3 3 3 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 CCM01360.1 - 0.82 9.4 28.4 0.1 12.3 7.1 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 CCM01360.1 - 0.98 8.8 21.5 1.5 8.2 2.4 2.5 2 1 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 CCM01360.1 - 2.6 7.5 26.9 0.36 10.3 6.9 2.7 1 1 1 2 2 2 0 IncA protein Syntaxin PF00804.20 CCM01360.1 - 2.8 8.1 16.3 8 6.6 0.1 3.0 3 0 0 3 3 3 0 Syntaxin FAD_binding_3 PF01494.14 CCM01361.1 - 2.2e-80 270.3 0.3 2.3e-63 214.3 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain Phe_hydrox_dim PF07976.7 CCM01361.1 - 8.7e-29 100.2 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 CCM01361.1 - 3.3e-07 29.1 0.6 5.3e-07 28.4 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 CCM01361.1 - 2.8e-06 26.4 2.0 4.6e-06 25.7 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CCM01361.1 - 2e-05 23.7 0.1 3.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CCM01361.1 - 2.4e-05 24.2 0.1 6e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCM01361.1 - 5.4e-05 22.2 0.9 0.00011 21.3 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCM01361.1 - 7.4e-05 22.7 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM01361.1 - 0.00048 20.2 0.1 0.00088 19.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM01361.1 - 0.00049 20.4 0.3 0.0035 17.7 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM01361.1 - 0.00066 18.6 1.2 0.0011 18.0 0.8 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 CCM01361.1 - 0.0018 17.2 1.3 0.0027 16.6 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CCM01361.1 - 0.0031 16.6 0.7 0.0055 15.8 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 CCM01361.1 - 0.0048 15.7 0.0 0.017 13.9 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase ApbA PF02558.11 CCM01361.1 - 0.012 15.0 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 CCM01361.1 - 0.017 13.7 0.1 0.026 13.1 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 CCM01361.1 - 0.022 14.4 0.2 0.071 12.7 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 CCM01361.1 - 0.051 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 CCM01361.1 - 0.067 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CPSase_L_chain PF00289.17 CCM01361.1 - 0.092 12.8 0.3 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain ThiF PF00899.16 CCM01361.1 - 0.093 12.5 0.4 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 ThiF family XdhC_C PF13478.1 CCM01361.1 - 0.13 12.6 0.1 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain CorA PF01544.13 CCM01365.1 - 7.4e-30 103.9 7.5 1.5e-26 93.0 4.7 3.0 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein MGAT2 PF05060.9 CCM01365.1 - 0.067 12.0 3.0 0.28 10.0 0.1 2.4 2 1 0 3 3 3 0 N-acetylglucosaminyltransferase II (MGAT2) DNA_pol_delta_4 PF04081.8 CCM01366.1 - 3.5e-23 82.2 0.0 9.2e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 FXR1P_C PF12235.3 CCM01366.1 - 2.1 8.4 15.6 1.1 9.3 8.7 1.9 1 1 1 2 2 2 0 Fragile X-related 1 protein C terminal WLM PF08325.5 CCM01367.1 - 5.3e-38 130.7 0.6 8.2e-37 126.8 0.0 2.0 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.18 CCM01367.1 - 2.1e-10 39.8 0.0 4.7e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CCM01367.1 - 3.2e-05 24.0 0.2 0.00012 22.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD PF11976.3 CCM01367.1 - 0.0028 17.2 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Peptidase_MA_2 PF13485.1 CCM01367.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily SprT-like PF10263.4 CCM01367.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SprT-like family BTB PF00651.26 CCM01368.1 - 2.9e-10 40.1 0.0 5.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_M20 PF01546.23 CCM01369.1 - 6.6e-10 38.7 0.5 1e-09 38.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCM01369.1 - 6.5e-06 25.8 0.1 2.5e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain p450 PF00067.17 CCM01370.1 - 6.9e-75 252.3 0.0 8.5e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.1 CCM01371.1 - 6.2e-14 52.5 0.0 1.3e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM01371.1 - 4.8e-12 46.0 0.0 9.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.11 CCM01372.1 - 5.7e-58 196.6 0.2 9.8e-58 195.8 0.1 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 CCM01372.1 - 1.9e-05 24.9 0.0 4.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Gln-synt_C PF00120.19 CCM01373.1 - 4.1e-54 183.4 0.0 6.1e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Cellulase PF00150.13 CCM01373.1 - 1.8e-13 50.3 0.0 1.5e-08 34.1 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) NAD_binding_4 PF07993.7 CCM01374.1 - 3.3e-36 124.4 0.1 6.6e-36 123.4 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 CCM01374.1 - 6.3e-34 117.0 0.0 2.8e-32 111.6 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 CCM01374.1 - 4.3e-09 36.1 0.0 6.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM01374.1 - 0.00087 19.3 0.0 0.044 13.7 0.0 3.0 3 1 0 3 3 3 1 NADH(P)-binding PP-binding PF00550.20 CCM01374.1 - 0.007 16.5 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 CCM01374.1 - 0.053 12.2 0.0 0.12 11.0 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCM01374.1 - 0.1 12.4 0.0 0.37 10.6 0.0 2.0 1 0 0 1 1 1 0 short chain dehydrogenase Ribosomal_L14 PF00238.14 CCM01375.1 - 5.2e-43 145.6 0.8 6.5e-43 145.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hexokinase_1 PF00349.16 CCM01376.1 - 2e-69 233.0 0.0 2.7e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CCM01376.1 - 4.8e-35 120.9 0.2 3e-22 79.0 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_2 PF03727.11 CCM01377.1 - 1.8e-30 105.9 0.1 2.2e-30 105.6 0.1 1.0 1 0 0 1 1 1 1 Hexokinase YjgF_endoribonc PF14588.1 CCM01377.1 - 0.029 14.3 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease WD40 PF00400.27 CCM01378.1 - 4.5e-22 77.0 23.1 6.3e-05 22.6 1.5 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 CCM01378.1 - 5.4e-16 58.3 0.0 1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain MaoC_dehydratas PF01575.14 CCM01379.1 - 4e-26 90.7 0.0 1.8e-25 88.6 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CCM01379.1 - 0.0025 17.5 0.0 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Peptidase_M48 PF01435.13 CCM01381.1 - 4.9e-15 55.6 0.0 7.7e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 CCM01381.1 - 0.016 15.2 0.1 0.04 13.9 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily Peptidase_M50 PF02163.17 CCM01381.1 - 0.051 12.5 0.3 0.1 11.5 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M50 Svf1 PF08622.5 CCM01382.1 - 2.8e-30 105.4 0.0 3.2e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Svf1-like GTF2I PF02946.9 CCM01384.1 - 0.036 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 GTF2I-like repeat DUF155 PF02582.9 CCM01385.1 - 1.6e-40 138.8 0.0 2.3e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 TPR_19 PF14559.1 CCM01385.1 - 1.3e-12 47.8 6.1 0.00011 22.4 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM01385.1 - 3.1e-09 37.2 13.8 1.8e-05 25.3 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCM01385.1 - 1.3e-07 31.1 5.0 0.037 13.6 0.0 4.9 6 0 0 6 6 6 2 TPR repeat TPR_17 PF13431.1 CCM01385.1 - 1.1e-06 28.3 0.7 0.075 13.2 0.0 3.6 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM01385.1 - 3.3e-06 27.2 9.4 0.23 12.2 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCM01385.1 - 2e-05 24.4 0.3 0.57 10.1 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCM01385.1 - 3.6e-05 23.3 9.0 0.35 10.8 0.0 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCM01385.1 - 4.6e-05 23.1 0.4 0.00063 19.5 0.1 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 CCM01385.1 - 0.00029 20.2 1.6 13 5.6 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCM01385.1 - 0.016 14.9 0.7 5.7 7.0 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCM01385.1 - 6.1 7.5 8.4 1.7e+02 3.0 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat SART-1 PF03343.8 CCM01386.1 - 3.9e-126 421.8 52.0 5.6e-126 421.3 36.1 1.2 1 0 0 1 1 1 1 SART-1 family RNase_HII PF01351.13 CCM01387.1 - 1.3e-43 149.0 0.0 7.3e-42 143.2 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease HII MA3 PF02847.12 CCM01388.1 - 1.3e-19 69.9 0.0 6.5e-19 67.7 0.0 2.3 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 CCM01388.1 - 1.4e-19 70.3 0.6 2.2e-19 69.6 0.1 1.6 2 0 0 2 2 2 1 MIF4G domain Methyltransf_18 PF12847.2 CCM01389.1 - 2.6e-15 56.9 0.1 3.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM01389.1 - 8.4e-10 38.4 0.0 3.5e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CCM01389.1 - 1.9e-07 31.0 0.6 5e-07 29.7 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM01389.1 - 3.4e-05 24.2 0.2 0.00041 20.7 0.2 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM01389.1 - 5.2e-05 23.5 0.0 7.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM01389.1 - 7.7e-05 23.1 0.1 0.00018 21.9 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCM01389.1 - 0.00054 19.6 0.0 0.00068 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCM01389.1 - 0.00057 19.2 0.0 0.00088 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CCM01389.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DnaJ PF00226.26 CCM01390.1 - 9e-06 25.3 0.1 1.2e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CCM01390.1 - 8.1e-05 22.4 0.0 9.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Pam16 AAA_12 PF13087.1 CCM01391.1 - 4.6e-33 114.2 0.3 3.1e-32 111.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCM01391.1 - 1.8e-23 83.3 0.1 1.4e-11 44.4 0.1 2.5 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CCM01391.1 - 2e-15 56.8 0.0 1.6e-14 53.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCM01391.1 - 1.9e-11 43.5 0.0 4.8e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CCM01391.1 - 4.2e-05 23.5 0.3 0.00037 20.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain PhoH PF02562.11 CCM01391.1 - 0.00036 19.8 0.0 0.14 11.3 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 CCM01391.1 - 0.0032 17.6 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 CCM01391.1 - 0.0052 16.1 0.8 0.043 13.0 0.0 2.5 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA PF00004.24 CCM01391.1 - 0.0053 16.9 0.1 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CCM01391.1 - 0.0055 15.7 0.2 0.013 14.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 CCM01391.1 - 0.0063 15.4 0.1 0.013 14.4 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 CCM01391.1 - 0.012 14.4 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 CCM01391.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_RecD PF05127.9 CCM01391.1 - 0.014 15.0 0.1 0.12 12.0 0.1 2.3 1 1 0 1 1 1 0 Helicase Arch_ATPase PF01637.13 CCM01391.1 - 0.018 14.7 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase DEAD PF00270.24 CCM01391.1 - 0.018 14.5 0.0 0.087 12.3 0.0 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.10 CCM01391.1 - 0.025 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CCM01391.1 - 0.026 14.8 0.1 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCM01391.1 - 0.037 14.8 1.5 0.13 13.0 0.6 2.3 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 CCM01391.1 - 0.051 12.9 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CCM01391.1 - 0.066 12.7 1.0 0.83 9.1 0.1 2.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Terminase_6 PF03237.10 CCM01391.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 Terminase-like family DUF1827 PF08860.5 CCM01391.1 - 0.12 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) AAA_24 PF13479.1 CCM01391.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Carn_acyltransf PF00755.15 CCM01392.1 - 3e-99 332.7 0.0 3.5e-99 332.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PcrB PF01884.12 CCM01392.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 PcrB family DUF1767 PF08585.7 CCM01393.1 - 1.5e-13 50.7 0.0 4.5e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) DnaJ PF00226.26 CCM01394.1 - 1.4e-17 63.2 1.9 1.4e-17 63.2 1.3 2.8 3 0 0 3 3 3 1 DnaJ domain DUF2040 PF09745.4 CCM01394.1 - 0.014 15.2 8.5 0.014 15.2 5.9 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) CtaG_Cox11 PF04442.9 CCM01395.1 - 8.3e-56 187.9 0.0 1.1e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 LsmAD PF06741.8 CCM01397.1 - 1.7e-23 82.4 1.5 3.8e-23 81.3 1.1 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 CCM01397.1 - 0.0015 18.4 0.1 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 CCM01397.1 - 0.094 12.5 0.0 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Scd6-like Sm domain Mad3_BUB1_I PF08311.7 CCM01398.1 - 1.5e-29 102.3 1.5 2.9e-29 101.3 1.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 CCM01398.1 - 4.5e-17 62.0 0.0 7.6e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01398.1 - 2.4e-09 36.6 0.0 3.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 CCM01398.1 - 0.025 14.4 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Kinase-like PF14531.1 CCM01398.1 - 0.087 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like MtN3_slv PF03083.11 CCM01398.1 - 2.2 8.2 3.1 1 9.2 0.4 1.7 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange FliX PF10768.4 CCM01399.1 - 0.34 11.1 4.1 5.7 7.1 0.5 2.3 1 1 1 2 2 2 0 Class II flagellar assembly regulator RhoGEF PF00621.15 CCM01400.1 - 3.3e-29 102.0 0.5 5.5e-29 101.3 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 CCM01400.1 - 1.3e-27 96.9 0.0 1.9e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CCM01400.1 - 1.7e-12 47.4 0.0 5.3e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CCM01400.1 - 5.9e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 PH domain SOG2 PF10428.4 CCM01401.1 - 5.5 5.5 12.1 6.1 5.3 8.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein WD40 PF00400.27 CCM01402.1 - 7.4e-43 142.9 5.7 6.2e-09 35.4 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat Glyoxal_oxid_N PF07250.6 CCM01402.1 - 0.18 10.8 0.1 0.33 9.9 0.1 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Exo_endo_phos PF03372.18 CCM01403.1 - 2.1e-09 37.7 0.1 2.6e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Alpha-amylase PF00128.19 CCM01404.1 - 3.6e-29 102.1 0.0 1.3e-27 97.0 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 CCM01404.1 - 0.0003 18.7 0.4 0.05 11.3 0.0 2.4 2 1 0 2 2 2 2 Glycosyl hydrolase family 70 IncA PF04156.9 CCM01405.1 - 0.045 13.3 6.2 0.11 12.0 4.3 1.6 1 0 0 1 1 1 0 IncA protein Dscam_C PF12355.3 CCM01405.1 - 0.15 12.3 3.5 0.45 10.7 2.4 1.8 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal CAP_N PF01213.14 CCM01405.1 - 0.33 10.2 4.3 1.1 8.4 2.8 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal V_ATPase_I PF01496.14 CCM01405.1 - 0.55 8.0 2.4 0.89 7.3 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 CCM01405.1 - 1.4 7.7 9.3 9.3 5.0 6.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Myosin_tail_1 PF01576.14 CCM01408.1 - 0.00058 17.7 63.2 0.00058 17.7 43.8 3.2 2 1 1 3 3 3 1 Myosin tail Filament PF00038.16 CCM01408.1 - 0.0048 16.4 60.9 0.21 11.0 20.2 3.3 1 1 2 3 3 3 2 Intermediate filament protein ALIX_LYPXL_bnd PF13949.1 CCM01408.1 - 0.087 11.7 43.6 0.19 10.6 9.8 3.3 2 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV Rota_NSP4 PF01452.11 CCM01408.1 - 0.093 12.0 1.7 0.24 10.7 1.2 1.7 1 0 0 1 1 1 0 Rotavirus non structural protein Reo_sigmaC PF04582.7 CCM01408.1 - 0.29 10.2 10.2 0.28 10.3 1.9 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein PMEI PF04043.10 CCM01408.1 - 3.6 7.4 9.8 0.53 10.1 3.3 2.2 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor TMF_DNA_bd PF12329.3 CCM01408.1 - 4.7 7.1 70.1 0.036 13.8 4.8 6.9 3 1 3 7 7 7 0 TATA element modulatory factor 1 DNA binding Pas_Saposin PF09016.5 CCM01409.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Pas factor saposin fold Abhydrolase_1 PF00561.15 CCM01410.1 - 1.4e-28 100.0 0.0 3.2e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCM01410.1 - 3e-24 86.1 0.1 1e-23 84.4 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sad1_UNC PF07738.8 CCM01410.1 - 2.4e-23 82.4 0.0 1.9e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Abhydrolase_5 PF12695.2 CCM01410.1 - 1.4e-11 44.3 0.0 8.3e-11 41.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 CCM01410.1 - 0.018 13.5 0.0 0.03 12.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family C2 PF00168.25 CCM01411.1 - 9.6e-12 44.5 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Sugar_tr PF00083.19 CCM01414.1 - 6.1e-89 298.6 23.0 6.9e-89 298.4 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM01414.1 - 1.1e-14 54.0 31.4 6.8e-14 51.3 18.1 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCM01414.1 - 1.3e-06 27.0 21.1 0.00078 17.9 0.3 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein ABC_membrane PF00664.18 CCM01415.1 - 9.2e-58 195.8 24.3 5e-30 104.8 4.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCM01415.1 - 2.7e-50 170.2 0.0 3.7e-28 98.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCM01415.1 - 1.2e-08 35.3 6.1 0.015 15.2 0.0 4.8 3 2 1 4 4 4 2 AAA domain SMC_N PF02463.14 CCM01415.1 - 4.5e-08 32.5 0.3 0.0013 18.0 0.0 3.8 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CCM01415.1 - 4.3e-06 26.2 0.9 0.021 14.2 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 CCM01415.1 - 1.5e-05 25.1 1.2 0.031 14.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CCM01415.1 - 1.5e-05 24.9 1.3 0.09 12.7 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 CCM01415.1 - 1.7e-05 24.2 1.3 0.14 11.7 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 CCM01415.1 - 0.00019 21.9 2.3 0.096 13.1 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 CCM01415.1 - 0.00046 21.0 0.1 1.1 10.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCM01415.1 - 0.0006 19.0 1.8 0.24 10.5 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 CCM01415.1 - 0.00076 19.3 3.6 2.3 8.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 CCM01415.1 - 0.0029 17.3 2.2 0.78 9.4 0.2 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CCM01415.1 - 0.0036 17.1 5.1 0.13 12.0 0.9 2.7 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 CCM01415.1 - 0.0075 15.7 1.3 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 CCM01415.1 - 0.0096 15.5 1.7 0.2 11.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 CCM01415.1 - 0.014 15.5 2.2 5.8 7.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCM01415.1 - 0.014 15.7 0.0 9.5 6.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CCM01415.1 - 0.014 15.1 4.6 0.4 10.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 CCM01415.1 - 0.021 13.8 0.4 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 CCM01415.1 - 0.031 13.1 0.8 2.9 6.6 0.3 2.4 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 CCM01415.1 - 0.039 12.8 0.3 4.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 CCM01415.1 - 0.071 11.7 1.3 1.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 CCM01415.1 - 0.12 11.9 3.3 12 5.2 0.3 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 CCM01415.1 - 0.12 12.0 0.6 1.9 8.1 0.0 2.8 3 1 0 3 3 3 0 Archaeal ATPase AAA_10 PF12846.2 CCM01415.1 - 0.13 11.6 5.6 2.4 7.5 0.1 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_13 PF13166.1 CCM01415.1 - 0.13 10.6 0.0 0.28 9.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCM01415.1 - 0.19 11.9 1.1 20 5.4 0.0 3.2 3 0 0 3 3 2 0 RNA helicase UPF0079 PF02367.12 CCM01415.1 - 0.22 11.1 3.0 0.42 10.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 CCM01415.1 - 0.6 8.8 9.0 5.3 5.7 0.2 3.2 3 0 0 3 3 3 0 ArgK protein cobW PF02492.14 CCM01415.1 - 1.6 8.1 7.8 1.2 8.5 0.3 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCM01415.1 - 2.5 8.3 4.6 29 4.9 0.2 3.1 3 0 0 3 3 2 0 AAA domain Fungal_trans PF04082.13 CCM01416.1 - 2e-08 33.4 0.0 3.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 CCM01417.1 - 2.3e-70 237.4 0.0 2.7e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_4 PF13147.1 CCM01419.1 - 0.09 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase p450 PF00067.17 CCM01420.1 - 1.1e-49 169.2 0.0 1.4e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM01421.1 - 0.00032 19.3 0.1 0.00037 19.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Actin PF00022.14 CCM01422.1 - 3e-50 170.8 0.0 4.7e-27 94.4 0.0 2.1 2 0 0 2 2 2 2 Actin Ras PF00071.17 CCM01423.1 - 2.7e-64 215.4 0.0 3.1e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM01423.1 - 7.7e-20 71.5 0.0 1.1e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM01423.1 - 4.8e-14 51.9 0.1 6.1e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM01423.1 - 8.4e-06 25.3 0.0 2e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCM01423.1 - 1.8e-05 24.0 0.0 2.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCM01423.1 - 0.00029 20.7 0.0 0.00054 19.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCM01423.1 - 0.018 14.3 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 CCM01423.1 - 0.029 14.3 0.1 0.046 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CCM01423.1 - 0.033 13.3 0.0 0.062 12.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCM01423.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 CCM01423.1 - 0.049 12.8 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCM01423.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CCM01423.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 CCM01423.1 - 0.099 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Septin AAA PF00004.24 CCM01423.1 - 0.14 12.4 0.0 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.1 CCM01424.1 - 2.3e-12 47.0 0.0 7e-09 35.6 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCM01424.1 - 1.2e-06 28.0 0.8 6.6e-05 22.3 0.0 3.1 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CCM01424.1 - 8.9e-05 22.5 0.2 0.0034 17.4 0.0 3.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 CCM01424.1 - 0.0021 18.1 0.0 0.065 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Syntaxin PF00804.20 CCM01424.1 - 0.0079 16.3 0.6 0.024 14.7 0.4 1.8 1 0 0 1 1 1 1 Syntaxin AAA_12 PF13087.1 CCM01424.1 - 0.031 13.6 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.1 CCM01424.1 - 0.2 11.3 4.8 3.2 7.4 0.1 3.5 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.23 CCM01424.1 - 0.55 9.9 5.1 1.9 8.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BAR PF03114.13 CCM01425.1 - 5.1e-24 85.0 1.1 5.3e-16 58.8 0.7 2.1 2 0 0 2 2 2 2 BAR domain SH3_1 PF00018.23 CCM01425.1 - 2.2e-14 52.5 0.1 3.8e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCM01425.1 - 2.3e-13 49.5 0.2 4.1e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCM01425.1 - 1.3e-11 43.7 0.1 2.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 CCM01425.1 - 2.1 7.6 9.6 3.1 7.0 6.7 1.2 1 0 0 1 1 1 0 Vta1 like SBDS_C PF09377.5 CCM01426.1 - 9.9e-38 128.6 0.3 2e-37 127.6 0.2 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 CCM01426.1 - 8.1e-34 115.2 1.3 1.6e-33 114.3 0.9 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Tox-ART-HYD1 PF15633.1 CCM01426.1 - 0.04 14.7 0.1 0.18 12.6 0.0 2.0 2 0 0 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase p450 PF00067.17 CCM01427.1 - 2e-54 184.8 0.0 2.6e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1541 PF07563.6 CCM01427.1 - 0.065 12.9 1.1 0.17 11.5 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) DOT1 PF08123.8 CCM01428.1 - 3e-65 219.3 0.0 4.2e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CCM01428.1 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCM01428.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DEAD PF00270.24 CCM01429.1 - 3e-32 111.4 0.0 6.7e-32 110.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM01429.1 - 4.5e-27 93.7 0.0 2.4e-26 91.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CCM01429.1 - 0.012 14.7 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit HET PF06985.6 CCM01430.1 - 5.6e-24 84.8 0.0 3.3e-23 82.4 0.0 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) LSM PF01423.17 CCM01431.1 - 3.1e-07 29.8 0.0 3.8e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF4444 PF14563.1 CCM01431.1 - 0.042 13.2 0.1 0.12 11.8 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4444) Chorismate_synt PF01264.16 CCM01432.1 - 5.6e-133 442.7 0.0 7.9e-133 442.2 0.0 1.2 1 0 0 1 1 1 1 Chorismate synthase Secretin_N_2 PF07655.8 CCM01433.1 - 0.015 15.6 0.2 0.042 14.2 0.0 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain UPF0052 PF01933.13 CCM01434.1 - 1.1e-45 156.2 0.0 1.5e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 BChl_A PF02327.12 CCM01434.1 - 0.011 14.4 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriochlorophyll A protein Asp PF00026.18 CCM01437.1 - 6.3e-18 65.0 12.8 2e-10 40.4 0.2 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Brr6_like_C_C PF10104.4 CCM01438.1 - 5.4e-42 142.5 1.1 6.8e-42 142.1 0.7 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CLP_protease PF00574.18 CCM01439.1 - 1.8e-74 249.3 0.0 2.3e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Clp protease MOSC PF03473.12 CCM01440.1 - 2e-11 43.4 0.0 4.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 CCM01440.1 - 4.4e-07 29.6 0.0 2.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain DUF682 PF05081.7 CCM01443.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF682) Histone PF00125.19 CCM01444.1 - 4.5e-30 103.5 0.8 8.8e-30 102.6 0.6 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCM01444.1 - 1.6e-05 24.9 0.1 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCM01444.1 - 0.00078 19.4 2.3 0.0017 18.3 0.1 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCM01444.1 - 0.018 14.7 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 CCM01444.1 - 0.2 10.8 0.1 0.2 10.8 0.1 1.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Peptidase_S10 PF00450.17 CCM01445.1 - 1.6e-52 179.0 0.0 1.8e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCM01445.1 - 0.00067 19.5 1.4 0.0062 16.4 0.9 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family MOSC_N PF03476.11 CCM01446.1 - 1.2e-14 53.9 0.0 3.5e-14 52.5 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 CCM01446.1 - 6.7e-11 41.7 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain CDP-OH_P_transf PF01066.16 CCM01447.1 - 1.6e-13 50.8 0.2 1.6e-13 50.8 0.2 2.7 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase tRNA-synt_His PF13393.1 CCM01448.1 - 2.5e-36 125.2 2.0 3.6e-32 111.6 0.0 3.2 3 1 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CCM01448.1 - 1.1e-17 64.2 0.0 2.8e-17 62.8 0.0 1.7 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCM01448.1 - 6.2e-09 35.6 0.0 1.9e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 CCM01448.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) COX5A PF02284.11 CCM01449.1 - 1e-37 128.4 0.4 1.8e-37 127.5 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Ank_4 PF13637.1 CCM01449.1 - 2.3e-15 56.6 0.1 2.7e-08 34.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCM01449.1 - 2.7e-15 56.4 0.3 1.5e-13 50.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCM01449.1 - 4.5e-14 52.1 0.3 7.7e-09 35.5 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCM01449.1 - 2.1e-13 49.3 2.6 1.3e-05 24.7 0.0 3.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CCM01449.1 - 3.2e-11 42.3 0.2 3.9e-05 23.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF1115 PF06544.7 CCM01450.1 - 1.2e-10 41.1 0.1 2.2e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Adhes-Ig_like PF09085.5 CCM01450.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like PUF PF00806.14 CCM01451.1 - 2e-27 93.1 0.2 1.7e-07 30.3 0.0 5.9 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat Pkinase PF00069.20 CCM01452.1 - 8.7e-76 254.4 0.0 1.1e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01452.1 - 3.3e-39 134.5 0.0 4.7e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM01452.1 - 1.3e-06 27.6 0.0 2.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.6 CCM01452.1 - 2.5e-06 27.5 1.0 4.3e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) RIO1 PF01163.17 CCM01452.1 - 0.0001 21.7 0.2 0.00032 20.0 0.2 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 CCM01452.1 - 0.014 15.1 2.7 0.11 12.1 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 CCM01452.1 - 0.051 12.6 0.4 0.25 10.3 0.3 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 CCM01452.1 - 0.1 11.1 0.1 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC CHAT PF12770.2 CCM01453.1 - 3.5e-41 141.2 0.1 5.6e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 CCM01453.1 - 2.2e-19 69.1 1.3 0.66 9.9 0.0 12.1 9 4 6 15 15 15 5 Tetratricopeptide repeat TPR_11 PF13414.1 CCM01453.1 - 6.9e-16 57.6 6.1 0.12 11.9 0.0 10.4 6 3 8 14 14 14 5 TPR repeat TPR_8 PF13181.1 CCM01453.1 - 0.0005 19.6 0.8 1.1 9.2 0.2 6.0 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCM01453.1 - 0.0015 18.3 1.4 3.4 7.8 0.2 6.5 5 1 0 5 5 5 1 Tetratricopeptide repeat Packaging_FI PF14000.1 CCM01453.1 - 0.011 15.9 0.4 6.4 6.9 0.0 3.8 4 0 0 4 4 4 0 DNA packaging protein FI TPR_14 PF13428.1 CCM01453.1 - 0.023 15.2 3.4 34 5.4 0.0 6.6 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCM01453.1 - 0.047 13.4 2.7 1.3 8.9 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat OST-HTH PF12872.2 CCM01453.1 - 0.049 13.4 0.0 1.9e+02 1.9 0.0 4.9 4 0 0 4 4 4 0 OST-HTH/LOTUS domain RPN7 PF10602.4 CCM01453.1 - 0.089 12.1 0.0 2.1 7.7 0.0 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TOM20_plant PF06552.7 CCM01453.1 - 0.14 11.7 0.0 9.8 5.7 0.0 3.4 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.1 CCM01453.1 - 0.16 11.9 14.1 12 6.0 0.3 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCM01453.1 - 1.2 8.8 8.8 9.4 6.0 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat PLA2_B PF01735.13 CCM01454.1 - 1e-95 320.8 0.4 1.7e-95 320.0 0.3 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Amidohydro_1 PF01979.15 CCM01455.1 - 1.9e-07 31.0 0.0 5.3e-06 26.3 0.0 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CCM01455.1 - 2.1e-05 24.2 0.0 5.8e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CCM01455.1 - 0.0002 21.5 0.1 0.05 13.6 0.1 3.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CCM01455.1 - 0.0055 15.9 0.1 0.75 8.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Fe_hyd_lg_C PF02906.9 CCM01457.1 - 8.6e-34 117.0 0.0 1.2e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2321 PF10083.4 CCM01458.1 - 0.26 10.7 4.4 0.32 10.4 3.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) SNARE PF05739.14 CCM01459.1 - 2.3e-18 65.6 1.7 6.7e-18 64.1 1.2 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 CCM01459.1 - 2.1e-09 37.4 0.1 1.1e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 CCM01459.1 - 0.095 12.7 0.5 3 7.9 0.0 2.4 2 0 0 2 2 2 0 Syntaxin-like protein MS_channel PF00924.13 CCM01460.1 - 9.3e-22 77.3 0.1 1.8e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CCM01460.1 - 0.11 11.8 0.4 0.23 10.8 0.3 1.6 1 0 0 1 1 1 0 EF hand Aa_trans PF01490.13 CCM01461.1 - 1.7e-72 244.1 28.0 2e-72 243.9 19.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CCM01461.1 - 8.4e-05 21.5 13.2 8.4e-05 21.5 9.2 1.9 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2574 PF10836.3 CCM01461.1 - 0.086 12.5 0.2 45 3.8 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2574) YrhC PF14143.1 CCM01461.1 - 1.4 8.9 5.9 2 8.3 0.1 3.6 3 0 0 3 3 3 0 YrhC-like protein GHMP_kinases_N PF00288.21 CCM01462.1 - 1.8e-10 40.6 0.6 1.8e-10 40.6 0.4 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCM01462.1 - 1.8e-06 28.0 0.1 6.6e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal NFRKB_winged PF14465.1 CCM01462.1 - 0.018 14.8 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 NFRKB Winged Helix-like Ferrochelatase PF00762.14 CCM01463.1 - 1e-98 330.2 0.0 1.2e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 CCM01463.1 - 0.0012 18.9 0.1 3.5 7.7 0.0 3.2 3 0 0 3 3 3 2 CbiX RNA_pol_A_bac PF01000.21 CCM01465.1 - 1.3e-20 73.5 0.0 3.5e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCM01465.1 - 1.5e-15 56.0 0.0 2.1e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 CCM01465.1 - 0.052 13.0 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF22 zf-RING_2 PF13639.1 CCM01466.1 - 1.2e-11 44.1 2.0 8.4e-10 38.3 0.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CCM01466.1 - 1.3e-07 31.5 0.2 3.7e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CCM01466.1 - 2.6e-06 27.3 2.8 7.2e-06 25.9 0.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM01466.1 - 2.8e-05 23.7 0.6 7.7e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCM01466.1 - 3.2e-05 23.5 0.3 0.00035 20.1 0.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCM01466.1 - 0.0006 19.5 0.4 0.0016 18.2 0.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CCM01466.1 - 0.0014 18.2 1.1 0.0029 17.2 0.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM01466.1 - 0.045 13.6 1.4 0.14 12.0 0.4 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCM01466.1 - 0.057 13.1 1.1 0.12 12.0 0.3 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 CCM01466.1 - 0.1 12.6 1.3 0.2 11.7 0.9 1.4 1 0 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.9 CCM01466.1 - 0.12 11.8 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif FANCL_C PF11793.3 CCM01466.1 - 1.7 8.6 3.5 3.5 7.6 1.2 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain GTP_EFTU_D3 PF03143.12 CCM01467.1 - 2.5e-16 59.6 0.2 6.6e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.22 CCM01467.1 - 2.4e-12 46.6 0.1 7.9e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CCM01467.1 - 1.3e-09 38.0 2.8 3e-09 36.8 0.7 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCM01467.1 - 0.0036 16.8 0.1 0.011 15.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MobB PF03205.9 CCM01467.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IncA PF04156.9 CCM01468.1 - 0.33 10.5 8.3 0.5 9.9 5.8 1.2 1 0 0 1 1 1 0 IncA protein Glyco_hydro_18 PF00704.23 CCM01469.1 - 1e-94 317.8 1.5 1.2e-94 317.5 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PASTA PF03793.14 CCM01469.1 - 0.074 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 PASTA domain Pkinase PF00069.20 CCM01470.1 - 2.5e-39 135.0 0.0 8.7e-17 61.1 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01470.1 - 3.2e-16 59.2 0.0 1.3e-05 24.4 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_C PF00433.19 CCM01470.1 - 0.0057 17.1 0.6 0.021 15.3 0.0 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Homeobox PF00046.24 CCM01471.1 - 2.4e-16 59.0 6.0 4.4e-16 58.2 4.1 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCM01471.1 - 0.00063 19.4 0.2 0.00063 19.4 0.1 2.2 3 0 0 3 3 3 1 Homeobox KN domain ABC_tran PF00005.22 CCM01472.1 - 2.3e-48 163.9 0.0 3.8e-29 101.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCM01472.1 - 3.9e-15 56.5 0.2 0.0084 16.0 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 CCM01472.1 - 3.5e-12 46.0 0.0 0.00038 19.7 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 CCM01472.1 - 6.6e-09 35.3 0.2 1.3e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 CCM01472.1 - 2.6e-07 31.4 0.2 0.012 16.3 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCM01472.1 - 8.8e-07 28.3 1.2 0.04 13.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 CCM01472.1 - 2e-06 28.3 0.1 0.011 16.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 CCM01472.1 - 2.7e-06 27.3 0.0 0.002 18.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CCM01472.1 - 4.5e-06 26.5 0.0 0.054 13.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 CCM01472.1 - 1e-05 25.5 0.0 0.088 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CCM01472.1 - 1.2e-05 25.7 0.2 0.017 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCM01472.1 - 1.3e-05 25.3 0.2 0.35 10.8 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 CCM01472.1 - 1.8e-05 24.0 0.1 0.032 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 CCM01472.1 - 2.7e-05 24.1 0.2 0.28 10.9 0.0 2.8 3 0 0 3 3 2 2 Domain of unknown function DUF87 NACHT PF05729.7 CCM01472.1 - 3.5e-05 23.5 0.2 0.016 14.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 CCM01472.1 - 3.6e-05 23.9 0.1 0.22 11.6 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_10 PF12846.2 CCM01472.1 - 7.4e-05 22.3 0.3 0.75 9.1 0.0 3.3 4 0 0 4 4 3 2 AAA-like domain AAA_18 PF13238.1 CCM01472.1 - 9.8e-05 22.6 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 CCM01472.1 - 0.00054 18.8 0.4 0.21 10.3 0.1 2.3 2 0 0 2 2 2 2 ArgK protein HEAT PF02985.17 CCM01472.1 - 0.00097 19.0 1.4 11 6.3 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat AAA_13 PF13166.1 CCM01472.1 - 0.0011 17.5 0.0 1.1 7.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CCM01472.1 - 0.0011 18.7 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 CCM01472.1 - 0.0017 18.2 0.0 1.3 8.9 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CCM01472.1 - 0.0033 17.5 0.1 2.3 8.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_14 PF13173.1 CCM01472.1 - 0.0039 17.1 0.1 4.8 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 CCM01472.1 - 0.0056 16.2 0.2 7.5 6.0 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.1 CCM01472.1 - 0.0078 15.6 0.2 13 5.1 0.0 3.6 4 0 0 4 4 3 0 AAA domain CLASP_N PF12348.3 CCM01472.1 - 0.015 14.6 0.0 0.25 10.6 0.0 2.3 1 1 0 2 2 2 0 CLASP N terminal Tudor-knot PF11717.3 CCM01472.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain ATP_bind_1 PF03029.12 CCM01472.1 - 0.03 13.8 0.1 8.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 CCM01472.1 - 0.04 13.6 0.3 17 5.0 0.1 3.1 3 0 0 3 3 3 0 Archaeal ATPase Arf PF00025.16 CCM01472.1 - 0.043 13.0 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM01472.1 - 0.059 12.8 0.0 2.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 CCM01472.1 - 0.075 12.4 0.2 15 4.9 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CCM01472.1 - 0.084 12.3 0.0 6.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 CCM01472.1 - 0.089 11.4 0.1 0.37 9.4 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Adaptin_N PF01602.15 CCM01472.1 - 0.11 10.8 0.7 11 4.2 1.1 2.3 1 1 1 2 2 2 0 Adaptin N terminal region AAA_5 PF07728.9 CCM01472.1 - 0.11 12.2 0.6 14 5.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ABC_transp_aux PF09822.4 CCM01472.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 ABC-type uncharacterized transport system KAP_NTPase PF07693.9 CCM01472.1 - 0.12 11.2 0.5 1.9 7.3 0.0 2.8 3 1 0 3 3 3 0 KAP family P-loop domain AAA_15 PF13175.1 CCM01472.1 - 0.14 11.1 0.0 11 4.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain DUF3584 PF12128.3 CCM01472.1 - 0.17 9.2 1.9 2.8 5.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) zf-C2H2 PF00096.21 CCM01473.1 - 1.1e-14 53.7 5.1 2.2e-07 30.8 0.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCM01473.1 - 5.2e-12 45.4 4.9 6e-07 29.4 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCM01473.1 - 4.3e-09 36.0 3.4 0.00025 21.1 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCM01473.1 - 0.00015 21.8 1.0 0.0007 19.6 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 CCM01473.1 - 0.00028 20.4 0.7 0.042 13.5 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 CCM01473.1 - 0.052 13.6 1.1 0.052 13.6 0.8 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CCM01473.1 - 0.062 13.5 0.6 0.25 11.6 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 CCM01473.1 - 0.069 13.1 1.3 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-TRAF PF02176.13 CCM01473.1 - 0.078 13.3 0.3 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger PyrI_C PF02748.10 CCM01473.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 CCM01473.1 - 0.28 11.1 1.8 4 7.4 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger BolA PF01722.13 CCM01474.1 - 3.4e-24 84.5 0.6 1.2e-23 82.8 0.4 1.7 1 1 0 1 1 1 1 BolA-like protein Pyrid_oxidase_2 PF13883.1 CCM01477.1 - 3.8e-18 65.8 0.0 4.6e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DNA_ligase_A_M PF01068.16 CCM01478.1 - 9.1e-41 139.4 0.0 2e-38 131.8 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCM01478.1 - 1.2e-38 132.7 0.0 3e-38 131.3 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CCM01478.1 - 1.5e-13 50.9 0.0 2.3e-10 40.7 0.0 3.0 2 0 0 2 2 2 2 ATP dependent DNA ligase C terminal region vATP-synt_E PF01991.13 CCM01478.1 - 0.042 13.1 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit zf-C2H2 PF00096.21 CCM01479.1 - 3.1e-11 42.9 10.0 2.8e-06 27.3 0.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM01479.1 - 4.6e-11 42.2 4.3 3.5e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCM01479.1 - 3.4e-10 39.6 5.3 1.2e-07 31.6 0.3 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCM01479.1 - 0.00013 21.9 2.5 0.025 14.7 0.4 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM01479.1 - 0.0004 20.4 1.3 0.36 11.0 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type BolA PF01722.13 CCM01479.1 - 0.0095 15.8 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 1 BolA-like protein Acetyltransf_1 PF00583.19 CCM01480.1 - 2.1e-11 43.6 0.0 3.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCM01480.1 - 5.6e-07 29.6 0.0 2e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCM01480.1 - 0.0022 17.9 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCM01480.1 - 0.0032 17.3 0.0 0.0043 16.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCM01480.1 - 0.0039 17.3 0.0 0.0054 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCM01480.1 - 0.038 13.7 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein ClpB_D2-small PF10431.4 CCM01481.1 - 0.056 13.3 0.0 3.5 7.6 0.0 2.2 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Asp PF00026.18 CCM01482.1 - 2.7e-45 155.0 0.9 7.9e-45 153.4 0.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM01482.1 - 0.00069 19.6 0.1 0.013 15.4 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCM01482.1 - 0.018 14.5 0.0 0.062 12.8 0.0 1.9 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Cyclin PF08613.6 CCM01483.1 - 5.1e-09 36.7 0.0 1.3e-06 28.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 CCM01483.1 - 0.0068 15.9 0.0 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Fungal_trans_2 PF11951.3 CCM01484.1 - 1.7e-45 155.3 0.0 1.9e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM01485.1 - 8.2e-08 32.0 8.9 1.3e-07 31.4 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 CCM01485.1 - 2.8 6.4 8.7 3.9 6.0 6.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein zf-SNAP50_C PF12251.3 CCM01486.1 - 1.2e-16 60.7 0.1 1.8e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Asparaginase_2 PF01112.13 CCM01487.1 - 1.9e-26 92.5 0.0 3.5e-26 91.6 0.0 1.5 1 1 0 1 1 1 1 Asparaginase RNase_H2-Ydr279 PF09468.5 CCM01488.1 - 5.7e-54 183.3 0.0 6.6e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Pkinase PF00069.20 CCM01490.1 - 2.3e-62 210.4 0.0 2.8e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01490.1 - 2.5e-37 128.3 0.0 3.2e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM01490.1 - 2.4e-06 26.7 0.0 2.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CCM01490.1 - 0.073 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Slu7 PF11708.3 CCM01491.1 - 5.9e-86 288.1 14.3 5.9e-86 288.1 9.9 1.7 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor DUF2151 PF10221.4 CCM01491.1 - 0.078 11.1 1.7 0.16 10.0 1.2 1.5 1 0 0 1 1 1 0 Cell cycle and development regulator zf-CCHC_4 PF14392.1 CCM01491.1 - 0.087 12.5 0.6 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Vfa1 PF08432.5 CCM01491.1 - 4.6 7.2 12.6 2.8 7.9 0.3 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4592 PF15262.1 CCM01492.1 - 0.1 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) DUF1771 PF08590.5 CCM01492.1 - 0.26 11.3 3.9 0.41 10.6 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) SNF2_N PF00176.18 CCM01493.1 - 4.2e-67 226.0 0.3 8.7e-67 225.0 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CCM01493.1 - 9.1e-25 86.8 0.3 9.1e-25 86.8 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CCM01493.1 - 6e-15 54.6 9.9 4.7e-12 45.3 0.6 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CCM01493.1 - 3.3e-14 52.5 0.0 8e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 CCM01493.1 - 0.0099 15.9 0.0 0.085 12.9 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain TBP PF00352.16 CCM01493.1 - 0.011 15.0 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) AAA_22 PF13401.1 CCM01493.1 - 0.027 14.6 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain FlhC PF05280.6 CCM01493.1 - 0.028 13.8 0.1 0.086 12.3 0.1 1.8 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Asp PF00026.18 CCM01494.1 - 2.5e-24 86.1 3.0 5.4e-17 62.0 0.2 2.9 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCM01494.1 - 5e-06 26.9 3.0 8.7e-05 22.9 0.8 3.0 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.15 CCM01494.1 - 0.0052 16.6 0.0 0.34 10.8 0.0 2.9 3 0 0 3 3 3 1 Retroviral aspartyl protease TAXi_N PF14543.1 CCM01494.1 - 0.0059 16.5 0.8 0.42 10.5 0.3 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DUF3481 PF11980.3 CCM01494.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) ATP-sulfurylase PF01747.12 CCM01495.1 - 4e-88 294.3 0.4 5.6e-88 293.8 0.3 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CCM01495.1 - 6.8e-56 188.0 0.0 1.8e-55 186.7 0.0 1.7 2 0 0 2 2 2 1 PUA-like domain APS_kinase PF01583.15 CCM01495.1 - 1.1e-44 151.8 0.0 1.7e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 CCM01495.1 - 0.00088 20.0 0.0 0.0025 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCM01495.1 - 0.0028 16.8 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 CCM01495.1 - 0.013 15.8 0.0 0.045 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCM01495.1 - 0.032 14.1 0.5 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCM01495.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.7 CCM01495.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ERO1 PF04137.10 CCM01496.1 - 4.9e-118 394.2 0.0 6.2e-118 393.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ShK PF01549.19 CCM01496.1 - 0.038 14.3 0.3 0.15 12.4 0.2 2.0 1 0 0 1 1 1 0 ShK domain-like KH_1 PF00013.24 CCM01498.1 - 4.9e-70 231.0 35.6 2e-11 43.3 0.9 12.1 13 1 0 13 13 13 8 KH domain KH_3 PF13014.1 CCM01498.1 - 5.3e-53 175.9 27.3 1.1e-06 28.0 0.1 12.1 12 0 0 12 12 12 10 KH domain SLS PF14611.1 CCM01498.1 - 1.1e-08 34.7 11.8 0.096 12.1 0.0 7.4 7 1 1 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 CCM01498.1 - 1.3e-06 27.8 29.1 0.05 13.1 0.0 8.5 8 1 1 9 9 9 4 KH domain KH_4 PF13083.1 CCM01498.1 - 0.0018 17.8 5.0 2.5 7.8 0.2 4.6 4 0 0 4 4 4 2 KH domain RRM_1 PF00076.17 CCM01499.1 - 7.2e-11 41.5 0.0 0.00012 21.6 0.0 2.7 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM01499.1 - 3.9e-08 33.1 0.0 2e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 CCM01499.1 - 1.8e-07 30.7 0.2 4.2e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 CCM01499.1 - 0.011 15.6 0.0 0.051 13.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 CCM01500.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CCM01501.1 - 9.1e-23 79.6 6.6 4.4e-14 51.8 0.5 3.1 2 1 1 3 3 3 2 TPR repeat Metallophos PF00149.23 CCM01501.1 - 5.4e-21 74.8 0.1 9.6e-20 70.8 0.1 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_1 PF00515.23 CCM01501.1 - 1.2e-15 56.3 8.7 9.1e-08 31.3 0.7 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat PPP5 PF08321.7 CCM01501.1 - 3.8e-15 55.6 0.0 1.1e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_2 PF07719.12 CCM01501.1 - 5.9e-12 44.5 10.6 1.4e-06 27.7 0.6 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCM01501.1 - 8.3e-11 41.2 3.9 0.00035 20.5 0.0 3.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCM01501.1 - 3.1e-08 33.3 0.2 0.00064 19.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM01501.1 - 8.9e-08 32.6 1.5 0.0014 19.2 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM01501.1 - 9.9e-08 31.9 1.9 0.011 16.2 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCM01501.1 - 1e-07 32.1 1.6 0.00065 19.9 0.5 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCM01501.1 - 1.8e-05 24.2 5.5 0.00042 19.9 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCM01501.1 - 0.00043 20.5 3.9 0.002 18.4 0.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CCM01501.1 - 0.00062 19.8 6.2 0.006 16.6 4.2 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CCM01501.1 - 0.014 15.3 6.5 0.11 12.4 1.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Allantoicase PF03561.10 CCM01502.1 - 3.9e-90 299.1 0.0 9.4e-46 155.0 0.0 2.3 2 0 0 2 2 2 2 Allantoicase repeat IF-2B PF01008.12 CCM01502.1 - 1.6e-56 191.3 0.0 2.1e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ureidogly_hydro PF04115.7 CCM01502.1 - 4.6e-47 159.4 0.0 2.5e-46 157.0 0.0 2.2 3 0 0 3 3 3 1 Ureidoglycolate hydrolase ABC_tran PF00005.22 CCM01503.1 - 3.2e-46 157.0 0.2 2.9e-27 95.6 0.1 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCM01503.1 - 2.7e-40 138.5 22.8 8.6e-23 81.1 1.1 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 CCM01503.1 - 5.5e-12 45.3 5.8 0.0076 15.5 0.4 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCM01503.1 - 5.7e-11 42.9 2.2 0.014 15.4 0.2 4.3 2 2 0 3 3 3 3 AAA domain AAA_23 PF13476.1 CCM01503.1 - 1.1e-08 35.7 0.9 5.3e-05 23.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 CCM01503.1 - 1e-07 31.5 0.0 0.019 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCM01503.1 - 2.1e-07 30.3 0.2 0.0047 16.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CCM01503.1 - 2.7e-06 27.4 0.9 0.054 13.4 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 CCM01503.1 - 8.1e-06 24.9 0.0 0.0032 16.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CCM01503.1 - 3.8e-05 23.2 0.1 0.28 10.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 CCM01503.1 - 8.6e-05 22.2 0.4 0.3 10.8 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CCM01503.1 - 0.00013 22.4 0.4 1.1 9.7 0.0 3.6 3 0 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 CCM01503.1 - 0.00022 21.1 0.0 0.52 10.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 CCM01503.1 - 0.00042 20.4 1.4 0.25 11.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCM01503.1 - 0.0006 19.5 0.0 0.093 12.4 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase DUF87 PF01935.12 CCM01503.1 - 0.00061 19.6 1.8 0.04 13.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 CCM01503.1 - 0.00062 18.9 0.1 0.38 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCM01503.1 - 0.00066 20.4 0.0 2.1 9.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain Adeno_IVa2 PF02456.10 CCM01503.1 - 0.0022 16.7 0.1 0.015 13.9 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_10 PF12846.2 CCM01503.1 - 0.0025 17.3 1.8 1.9 7.8 0.0 2.6 2 1 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 CCM01503.1 - 0.0033 17.7 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCM01503.1 - 0.0071 16.0 0.3 8.1 6.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 CCM01503.1 - 0.0079 15.5 0.2 4.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.12 CCM01503.1 - 0.013 14.8 0.4 4.4 6.6 0.0 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCM01503.1 - 0.024 13.7 0.0 0.96 8.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.10 CCM01503.1 - 0.026 14.3 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 CCM01503.1 - 0.034 13.7 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CCM01503.1 - 0.039 13.6 0.0 1 9.1 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Dynamin_N PF00350.18 CCM01503.1 - 0.062 13.1 1.8 2.9 7.6 0.0 3.2 3 0 0 3 3 3 0 Dynamin family PduV-EutP PF10662.4 CCM01503.1 - 0.1 12.0 0.8 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CCM01503.1 - 0.11 12.6 0.2 13 5.9 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_15 PF13175.1 CCM01503.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CCM01503.1 - 0.13 12.1 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCM01503.1 - 0.2 11.8 1.4 1.7 8.8 0.0 3.0 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 CCM01503.1 - 0.81 9.1 3.0 2.3 7.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CCM01503.1 - 0.88 9.2 4.6 4.3 6.9 0.1 3.1 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.22 CCM01505.1 - 2.5e-08 34.3 0.0 4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCM01505.1 - 3.8e-05 23.8 0.2 4.3e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 CCM01505.1 - 0.0028 17.5 0.4 0.032 14.1 0.3 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 CCM01505.1 - 0.0049 16.1 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain GATA PF00320.22 CCM01506.1 - 4.3e-15 54.7 3.6 9.2e-15 53.7 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger TauD PF02668.11 CCM01507.1 - 2.7e-39 135.3 1.2 3.4e-39 135.0 0.0 1.6 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Mito_fiss_reg PF05308.6 CCM01507.1 - 2.8 7.2 6.3 4.4 6.6 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator XRN_N PF03159.13 CCM01508.1 - 7.2e-101 336.5 0.0 1.3e-100 335.6 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus GMP_synt_C PF00958.17 CCM01508.1 - 2.4e-41 139.3 0.1 5e-41 138.3 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CCM01508.1 - 3e-34 118.1 0.1 7.7e-34 116.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 CCM01508.1 - 1.8e-09 36.8 0.1 1.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CCM01508.1 - 5.4e-08 32.5 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 CCM01508.1 - 0.005 16.3 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 CCM01508.1 - 0.015 13.9 0.1 0.025 13.1 0.1 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.16 CCM01508.1 - 0.022 14.2 0.0 0.089 12.2 0.0 2.0 2 0 0 2 2 2 0 Asparagine synthase QueC PF06508.8 CCM01508.1 - 0.071 12.3 0.0 0.17 11.1 0.0 1.7 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF2392 PF10288.4 CCM01508.1 - 0.12 12.7 0.0 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) Amidase PF01425.16 CCM01509.1 - 1.7e-91 307.2 1.6 2.9e-90 303.2 1.0 2.1 1 1 0 1 1 1 1 Amidase PFK PF00365.15 CCM01509.1 - 0.11 11.3 0.0 0.64 8.9 0.0 1.9 2 0 0 2 2 2 0 Phosphofructokinase PrpF PF04303.8 CCM01510.1 - 1.3e-73 247.8 0.9 2.1e-73 247.2 0.7 1.3 1 0 0 1 1 1 1 PrpF protein Lon_C PF05362.8 CCM01511.1 - 1e-70 237.2 0.2 1.7e-70 236.5 0.1 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CCM01511.1 - 2.5e-38 131.8 0.2 2.5e-38 131.8 0.1 1.6 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CCM01511.1 - 2.2e-21 76.4 0.0 6.6e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 CCM01511.1 - 1.5e-08 34.1 0.0 3.7e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 CCM01511.1 - 1.1e-07 31.6 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCM01511.1 - 3.5e-06 27.0 0.0 1.2e-05 25.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CCM01511.1 - 5e-05 24.1 0.0 0.00025 21.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM01511.1 - 6.1e-05 23.0 0.1 0.00085 19.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.6 CCM01511.1 - 7e-05 21.6 0.0 0.00014 20.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 CCM01511.1 - 0.00048 20.2 0.0 0.007 16.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCM01511.1 - 0.00059 18.9 0.0 0.0021 17.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CCM01511.1 - 0.0011 19.2 2.6 0.0028 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCM01511.1 - 0.0014 18.5 0.0 0.0042 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CCM01511.1 - 0.0067 15.1 0.2 0.054 12.2 0.1 2.2 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 CCM01511.1 - 0.0083 16.2 0.0 0.098 12.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.20 CCM01511.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 CCM01511.1 - 0.013 15.4 0.7 0.032 14.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase Arch_ATPase PF01637.13 CCM01511.1 - 0.02 14.6 1.9 2.7 7.6 0.0 3.4 2 2 1 3 3 3 0 Archaeal ATPase NTPase_1 PF03266.10 CCM01511.1 - 0.025 14.2 0.1 0.13 11.9 0.0 2.2 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 CCM01511.1 - 0.026 13.9 0.0 0.07 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CCM01511.1 - 0.03 14.2 0.0 5.2 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CCM01511.1 - 0.042 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 CCM01511.1 - 0.046 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CCM01511.1 - 0.048 13.2 0.0 0.22 11.1 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCM01511.1 - 0.08 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 CCM01511.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCM01511.1 - 0.095 11.7 0.1 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CCM01511.1 - 0.14 11.9 0.2 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 CCM01511.1 - 0.39 10.6 1.7 6.4 6.6 0.0 2.9 2 1 1 3 3 3 0 AAA domain DUF2360 PF10152.4 CCM01511.1 - 1.7 8.8 7.3 6.9 6.9 2.3 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Cyt-b5 PF00173.23 CCM01512.1 - 1.8e-16 59.6 0.0 2.7e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 CCM01514.1 - 2e-09 36.9 0.0 3.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01514.1 - 0.00074 18.6 0.1 0.0014 17.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase AMP-binding PF00501.23 CCM01516.1 - 1.1e-31 109.6 0.1 1e-30 106.5 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCM01516.1 - 7.2e-29 100.4 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CCM01516.1 - 2.5e-11 43.4 0.0 9e-11 41.6 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM01516.1 - 0.00016 21.7 0.0 0.0027 17.7 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCM01516.1 - 0.0037 16.0 0.0 0.0078 14.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCM01516.1 - 0.058 13.3 0.4 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 short chain dehydrogenase DUF3262 PF11660.3 CCM01517.1 - 0.00072 19.5 4.4 0.00072 19.5 3.1 3.8 3 1 1 4 4 4 1 Protein of unknown function (DUF3262) RPE65 PF03055.10 CCM01518.1 - 6.2e-113 377.9 0.0 7.2e-113 377.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MIF4G PF02854.14 CCM01519.1 - 2.3e-26 92.5 0.6 6.6e-26 91.0 0.4 1.7 1 1 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CCM01519.1 - 2.4e-15 56.1 0.0 5.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DUF1968 PF09291.5 CCM01519.1 - 0.099 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) F-box-like PF12937.2 CCM01520.1 - 0.0019 17.8 3.9 0.0051 16.5 2.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM01520.1 - 0.046 13.4 0.5 0.046 13.4 0.3 2.6 2 0 0 2 2 2 0 F-box domain Glyco_hydro_28 PF00295.12 CCM01521.1 - 1.2e-35 123.0 8.6 1.9e-35 122.3 6.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4337 PF14235.1 CCM01522.1 - 3.8 7.3 6.3 6 6.6 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pkinase PF00069.20 CCM01524.1 - 1.4e-12 47.3 0.0 1.1e-10 41.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01524.1 - 3e-05 23.2 0.0 0.00014 21.0 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase ABC_tran PF00005.22 CCM01526.1 - 7.1e-29 100.8 0.0 1.6e-16 60.8 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCM01526.1 - 3e-05 24.1 0.0 0.18 11.7 0.0 2.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCM01526.1 - 0.00047 19.6 0.0 0.013 15.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 CCM01526.1 - 0.0061 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF3584 PF12128.3 CCM01526.1 - 0.26 8.5 0.0 0.36 8.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LRR_4 PF12799.2 CCM01527.1 - 0.15 11.7 1.7 1.2e+02 2.4 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CCM01527.1 - 0.85 9.8 5.3 9.5 6.6 0.1 4.8 6 0 0 6 6 6 0 Leucine Rich repeat Peptidase_M28 PF04389.12 CCM01529.1 - 1.9e-25 89.6 0.0 4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCM01529.1 - 0.00099 18.6 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1109 PF06532.6 CCM01529.1 - 0.0076 15.6 8.2 0.0076 15.6 5.7 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1109) Peptidase_M42 PF05343.9 CCM01529.1 - 0.047 12.4 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase adh_short PF00106.20 CCM01530.1 - 4e-28 98.4 2.9 5.6e-28 97.9 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM01530.1 - 1.4e-16 60.6 1.5 2e-16 60.1 1.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM01530.1 - 7.6e-11 42.2 0.7 1e-10 41.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCM01530.1 - 1.1e-05 25.0 0.5 1.8e-05 24.2 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CCM01530.1 - 8.7e-05 22.2 0.7 0.00024 20.8 0.2 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 CCM01530.1 - 0.00019 20.4 0.3 0.00034 19.6 0.2 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 CCM01530.1 - 0.034 13.2 0.5 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fzo_mitofusin PF04799.8 CCM01530.1 - 0.14 11.5 0.2 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 fzo-like conserved region Adeno_E1A PF02703.9 CCM01531.1 - 0.0034 16.8 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 2 Early E1A protein Tafi-CsgC PF10610.4 CCM01531.1 - 0.017 14.9 1.2 18 5.1 0.0 3.2 3 0 0 3 3 3 0 Thin aggregative fimbriae synthesis protein Coagulase PF08764.5 CCM01531.1 - 0.2 11.5 4.2 27 4.5 0.1 3.2 3 0 0 3 3 3 0 Staphylococcus aureus coagulase MDH PF02315.11 CCM01531.1 - 2.5 8.1 10.0 29 4.6 0.1 3.6 3 0 0 3 3 3 0 Methanol dehydrogenase beta subunit adh_short PF00106.20 CCM01532.1 - 4.7e-28 98.1 5.8 6.3e-28 97.7 4.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM01532.1 - 1.8e-15 57.3 0.4 2.5e-15 56.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM01532.1 - 3.1e-15 56.2 2.7 4.3e-15 55.8 1.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM01532.1 - 2e-06 27.4 1.0 4.1e-06 26.4 0.7 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CCM01532.1 - 1.8e-05 23.8 0.1 2.3e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CCM01532.1 - 0.00016 21.3 0.8 0.00041 20.0 0.3 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GST_N_2 PF13409.1 CCM01532.1 - 0.063 13.2 0.1 0.14 12.1 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HEAT_2 PF13646.1 CCM01533.1 - 1.1e-47 160.1 8.6 1.2e-16 60.7 0.1 4.1 2 2 3 5 5 5 5 HEAT repeats HEAT_PBS PF03130.11 CCM01533.1 - 2.2e-23 80.3 0.5 0.0005 20.2 0.0 6.8 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 CCM01533.1 - 3.6e-13 48.3 0.6 0.037 14.1 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 CCM01533.1 - 1.2e-10 41.5 4.3 0.065 13.7 0.1 5.9 4 2 3 7 7 7 4 HEAT-like repeat Arm PF00514.18 CCM01533.1 - 0.0019 17.9 0.3 0.39 10.6 0.1 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat DUF1546 PF07571.8 CCM01533.1 - 0.0086 16.1 0.1 0.63 10.1 0.0 3.4 4 1 0 4 4 4 1 Protein of unknown function (DUF1546) RTBV_P12 PF06361.6 CCM01533.1 - 0.026 14.7 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Choline_kin_N PF04428.9 CCM01533.1 - 0.03 13.7 0.3 0.36 10.3 0.0 2.8 4 0 0 4 4 4 0 Choline kinase N terminus Ribosomal_L10 PF00466.15 CCM01534.1 - 8.9e-20 70.4 0.0 1.3e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RRF PF01765.14 CCM01534.1 - 0.11 11.9 1.8 0.12 11.8 0.4 1.7 2 0 0 2 2 2 0 Ribosome recycling factor adh_short PF00106.20 CCM01536.1 - 5.3e-28 98.0 3.4 7e-28 97.6 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM01536.1 - 4.4e-12 46.0 1.8 6.2e-12 45.5 1.3 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCM01536.1 - 1.3e-05 24.8 0.5 4e-05 23.3 0.2 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CCM01536.1 - 0.0043 16.5 0.1 0.0064 15.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CCM01536.1 - 0.028 13.3 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 CCM01537.1 - 2.7e-27 95.7 5.1 4e-27 95.1 3.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM01537.1 - 4.9e-15 55.6 3.0 7.4e-15 55.0 2.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM01537.1 - 6.1e-12 45.8 0.5 9e-12 45.2 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CCM01537.1 - 0.00018 21.2 0.3 0.00043 20.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CCM01537.1 - 0.0011 18.4 0.5 0.0017 17.8 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 CCM01537.1 - 0.0057 15.7 0.6 0.18 10.8 0.2 2.8 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2493 PF10686.4 CCM01537.1 - 0.053 13.0 0.1 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) DUF1776 PF08643.5 CCM01537.1 - 0.098 11.7 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 CCM01537.1 - 0.12 11.2 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 CCM01538.1 - 7.8e-29 100.7 3.9 1.1e-28 100.2 2.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM01538.1 - 2.7e-15 56.4 2.3 3.7e-15 56.0 1.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM01538.1 - 6.6e-08 32.2 0.2 1.1e-07 31.6 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CCM01538.1 - 9.9e-06 25.2 0.7 2.3e-05 24.0 0.5 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 CCM01538.1 - 0.004 16.1 0.2 0.007 15.2 0.2 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein PA PF02225.17 CCM01538.1 - 0.023 14.3 0.4 0.044 13.4 0.3 1.5 1 0 0 1 1 1 0 PA domain DUF1611 PF07755.6 CCM01538.1 - 0.039 12.5 1.4 1 7.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1611) THF_DHG_CYH_C PF02882.14 CCM01538.1 - 0.075 12.0 1.6 0.17 10.9 0.2 2.2 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoMet_dc PF02675.10 CCM01538.1 - 0.087 12.7 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase DUF1776 PF08643.5 CCM01538.1 - 0.091 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 CCM01539.1 - 9.4e-26 90.7 2.2 1.3e-25 90.2 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM01539.1 - 4.3e-13 49.3 0.8 6e-13 48.8 0.6 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCM01539.1 - 0.0001 21.9 0.3 0.00022 20.9 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 CCM01539.1 - 0.063 12.1 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 CCM01539.1 - 0.065 12.3 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_S28 PF05577.7 CCM01542.1 - 5.7e-47 160.2 3.8 4e-46 157.4 2.6 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CCM01542.1 - 0.021 14.6 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCM01542.1 - 0.024 13.8 0.2 0.08 12.1 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Adaptin_binding PF10199.4 CCM01544.1 - 1.3e-09 38.4 3.4 0.00034 20.9 0.0 2.4 2 0 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 TraE PF05309.6 CCM01545.1 - 0.074 12.1 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 TraE protein Methyltransf_11 PF08241.7 CCM01546.1 - 1.1e-11 44.9 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM01546.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM01546.1 - 3.5e-08 34.0 0.0 8.7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM01546.1 - 5.9e-08 32.1 0.0 9.1e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CCM01546.1 - 6.7e-08 32.8 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM01546.1 - 1.5e-07 31.4 0.0 4.6e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM01546.1 - 1.5e-07 31.0 0.0 3.6e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM01546.1 - 4.9e-06 26.9 0.0 1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CCM01546.1 - 0.0018 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 CCM01546.1 - 0.0043 16.1 0.0 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 CCM01546.1 - 0.088 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.11 CCM01546.1 - 0.09 11.0 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 CCM01546.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 CCM01546.1 - 0.26 10.9 0.0 0.92 9.0 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Nup84_Nup100 PF04121.8 CCM01547.1 - 1.8e-79 267.2 0.0 3.2e-45 154.0 0.0 2.4 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 PLDc PF00614.17 CCM01548.1 - 1.5e-17 62.7 2.6 8.4e-09 34.9 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CCM01548.1 - 5.3e-14 52.0 0.0 5.8e-07 29.3 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain ADH_zinc_N PF00107.21 CCM01549.1 - 1.7e-18 66.4 0.0 2.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM01549.1 - 9.8e-05 23.2 0.0 0.00036 21.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 CCM01549.1 - 0.006 16.1 0.1 0.0087 15.6 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 CCM01549.1 - 0.0078 16.2 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 CCM01550.1 - 3.9e-18 65.2 0.1 5.9e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM01550.1 - 1.7e-05 25.6 0.0 7.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 CCM01550.1 - 0.0085 15.6 0.1 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 CCM01550.1 - 0.0093 15.9 0.1 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding PARP PF00644.15 CCM01551.1 - 4.1e-12 45.9 0.1 8.3e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 CCM01551.1 - 9e-07 28.4 0.0 1.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCM01551.1 - 0.037 13.7 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B Solute_trans_a PF03619.11 CCM01552.1 - 7.1e-65 219.0 15.1 8.4e-65 218.8 10.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glycos_transf_4 PF00953.16 CCM01552.1 - 2.5 7.9 8.4 1 9.1 0.8 2.6 2 2 0 2 2 2 0 Glycosyl transferase family 4 Macro_2 PF14519.1 CCM01555.1 - 0.082 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Macro-like domain AMP-binding PF00501.23 CCM01556.1 - 4e-63 213.2 0.0 3.6e-31 108.0 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CCM01556.1 - 1.5e-14 54.6 0.9 3.1e-13 50.4 0.2 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Pectate_lyase_3 PF12708.2 CCM01557.1 - 4.4e-18 66.2 5.4 9.1e-16 58.6 0.1 2.6 3 0 0 3 3 3 2 Pectate lyase superfamily protein VRR_NUC PF08774.6 CCM01558.1 - 2e-20 72.6 0.0 6.2e-20 71.0 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain WD40 PF00400.27 CCM01559.1 - 6.8e-05 22.5 0.4 0.45 10.4 0.0 4.3 3 1 0 3 3 3 2 WD domain, G-beta repeat BBS2_N PF14781.1 CCM01559.1 - 0.024 14.2 0.1 4.8 6.8 0.0 3.4 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal TSC22 PF01166.13 CCM01559.1 - 0.049 13.6 1.0 0.11 12.4 0.7 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family HALZ PF02183.13 CCM01559.1 - 0.37 10.5 2.2 0.8 9.4 1.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pam17 PF08566.5 CCM01562.1 - 4.5e-57 192.5 0.0 1.2e-38 132.5 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial import protein Pam17 DUF3429 PF11911.3 CCM01563.1 - 5.9e-36 123.5 15.1 7.8e-36 123.1 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) AAA_5 PF07728.9 CCM01564.1 - 2.2e-11 43.6 0.0 4.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCM01564.1 - 3.4e-07 30.3 0.0 5.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCM01564.1 - 5.6e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCM01564.1 - 6.9e-06 26.1 0.1 0.00014 21.9 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCM01564.1 - 9.9e-05 22.4 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCM01564.1 - 0.0063 15.7 0.1 0.052 12.7 0.0 2.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCM01564.1 - 0.011 15.9 0.0 0.04 14.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 CCM01564.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 CCM01564.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Sigma54_activat PF00158.21 CCM01564.1 - 0.018 14.5 0.0 0.035 13.5 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 CCM01564.1 - 0.028 13.5 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CCM01564.1 - 0.045 13.6 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCM01564.1 - 0.2 12.5 0.0 0.39 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCM01564.1 - 0.35 10.5 0.0 17 4.9 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase Aha1_N PF09229.6 CCM01566.1 - 1e-24 86.8 0.0 1.4e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CCM01566.1 - 3.8e-13 49.6 0.1 7.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Hamartin PF04388.7 CCM01566.1 - 0.026 13.2 0.1 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.20 CCM01568.1 - 1.2e-69 234.4 0.0 1.7e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01568.1 - 9.6e-48 162.4 0.0 1.4e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM01568.1 - 8.2e-06 24.9 0.0 0.00023 20.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCM01568.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1682 PF07946.9 CCM01569.1 - 7.1e-65 218.9 0.0 8.1e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.7 CCM01569.1 - 0.35 10.7 7.4 0.49 10.2 5.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3818 PF12825.2 CCM01571.1 - 1.9e-113 378.6 0.1 2.4e-113 378.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCM01571.1 - 7.1e-26 90.4 0.2 1.7e-25 89.2 0.1 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 CCM01571.1 - 2.3e-12 46.6 0.0 9.6e-12 44.7 0.0 2.1 1 0 0 1 1 1 1 PX domain TPR_7 PF13176.1 CCM01571.1 - 0.081 12.7 0.1 0.34 10.7 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3851 PF12962.2 CCM01571.1 - 0.093 12.7 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3851) Pkinase PF00069.20 CCM01572.1 - 7.3e-65 218.6 0.1 6.1e-43 146.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01572.1 - 6.9e-28 97.4 0.1 2.2e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CCM01572.1 - 0.00015 20.9 0.2 0.00077 18.5 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM01572.1 - 0.0003 20.6 1.4 0.034 13.8 0.1 2.8 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCM01572.1 - 0.00037 19.5 0.0 0.00076 18.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CCM01572.1 - 0.0014 19.1 0.0 0.0014 19.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 CCM01572.1 - 0.029 13.1 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 CCM01572.1 - 0.035 12.9 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 CCM01572.1 - 0.039 13.3 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family BCDHK_Adom3 PF10436.4 CCM01573.1 - 5e-35 120.4 0.0 7.4e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCM01573.1 - 1.7e-13 50.2 0.0 1.4e-12 47.3 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med20 PF08612.6 CCM01573.1 - 1.1e-08 34.4 0.0 1.4e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ORC4_C PF14629.1 CCM01574.1 - 2.8e-34 118.3 0.0 5e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 CCM01574.1 - 7.8e-20 71.6 0.5 1.9e-19 70.3 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCM01574.1 - 0.0031 17.6 0.0 0.0076 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCM01574.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 CCM01574.1 - 0.014 15.6 0.0 0.18 11.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CCM01574.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase RNA12 PF10443.4 CCM01574.1 - 0.019 13.5 0.0 0.035 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein AAA_14 PF13173.1 CCM01574.1 - 0.027 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CCM01574.1 - 0.084 12.5 0.1 0.56 9.8 0.1 2.2 1 1 0 1 1 1 0 NACHT domain DUF3759 PF12585.3 CCM01575.1 - 2e-40 136.5 5.1 2.8e-40 136.1 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3336 PF11815.3 CCM01576.1 - 3e-21 75.4 6.6 8.3e-13 48.0 1.3 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3336) Patatin PF01734.17 CCM01576.1 - 3.2e-20 72.9 0.1 7.2e-20 71.7 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase KIF1B PF12423.3 CCM01576.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Kinesin protein 1B Rootletin PF15035.1 CCM01577.1 - 0.002 18.1 0.8 0.0047 16.9 0.5 1.6 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Hemerythrin PF01814.18 CCM01577.1 - 0.03 14.4 2.9 0.24 11.5 2.0 2.3 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Malic_M PF03949.10 CCM01578.1 - 6.2e-78 261.8 0.0 8.7e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CCM01578.1 - 4.6e-59 199.0 0.0 6.8e-59 198.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PUB PF09409.5 CCM01579.1 - 1.1e-11 44.2 0.0 1.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 PUB domain PCI PF01399.22 CCM01582.1 - 7.2e-13 48.7 0.1 1.3e-11 44.7 0.0 2.8 3 0 0 3 3 3 1 PCI domain TPR_14 PF13428.1 CCM01582.1 - 0.063 13.9 2.2 1.6 9.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CRS1_YhbY PF01985.16 CCM01582.1 - 0.11 12.5 0.4 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain Pkinase PF00069.20 CCM01583.1 - 2.6e-75 252.9 0.0 3.9e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01583.1 - 4.2e-37 127.6 0.0 6.5e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM01583.1 - 1.4e-07 30.7 0.0 2.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.27 CCM01584.1 - 8.2e-12 44.5 0.3 0.074 12.9 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Asp PF00026.18 CCM01585.1 - 1.5e-113 379.2 0.1 1.8e-113 379.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM01585.1 - 1.1e-09 38.4 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCM01585.1 - 6.9e-07 28.9 0.0 1.3e-05 24.8 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CCM01585.1 - 4.6e-05 23.8 0.0 0.021 15.2 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease Bromodomain PF00439.20 CCM01586.1 - 2.5e-23 81.7 0.1 5.2e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 Bromodomain FAT PF02259.18 CCM01587.1 - 3.1e-70 236.9 5.4 6.1e-70 235.9 3.8 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CCM01587.1 - 4.9e-18 65.4 0.4 1.2e-17 64.1 0.3 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CCM01587.1 - 0.0011 18.3 0.0 0.0033 16.8 0.0 2.0 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 CCM01587.1 - 0.027 14.1 1.6 0.14 11.8 0.5 2.9 2 0 0 2 2 2 0 TPR repeat DUF3671 PF12420.3 CCM01588.1 - 0.21 11.6 0.7 0.44 10.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function WH2 PF02205.15 CCM01589.1 - 9e-08 31.4 5.0 1.7e-07 30.6 0.9 2.5 2 0 0 2 2 2 1 WH2 motif Thioredoxin PF00085.15 CCM01590.1 - 2.6e-52 174.8 1.5 4.4e-25 87.3 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CCM01590.1 - 1e-32 113.4 0.8 3.4e-29 101.9 0.1 3.6 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CCM01590.1 - 3.6e-10 39.7 0.1 3.5e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CCM01590.1 - 3.8e-10 39.7 0.7 0.0023 17.9 0.0 3.5 3 2 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CCM01590.1 - 1.8e-08 34.5 0.5 0.0067 16.6 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 CCM01590.1 - 1.4e-05 24.6 0.1 0.14 11.6 0.0 2.5 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.16 CCM01590.1 - 1.4e-05 24.7 0.3 0.021 14.5 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_4 PF13462.1 CCM01590.1 - 0.0053 16.7 0.6 2.2 8.2 0.1 2.9 3 0 0 3 3 3 1 Thioredoxin TCTP PF00838.12 CCM01591.1 - 4.7e-63 212.0 1.3 5.3e-63 211.9 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UTP15_C PF09384.5 CCM01592.1 - 1.9e-46 157.4 0.0 3.5e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CCM01592.1 - 5.2e-29 99.0 4.3 2.5e-06 27.1 0.2 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CCM01592.1 - 5.4e-05 21.6 0.2 0.0011 17.4 0.1 2.3 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.3 CCM01592.1 - 0.011 13.9 0.3 0.052 11.6 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 CAF1C_H4-bd PF12265.3 CCM01592.1 - 0.033 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CCM01592.1 - 0.09 12.4 0.0 3.2 7.4 0.0 2.8 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A CTNNBL PF08216.6 CCM01593.1 - 1.2e-28 98.8 0.4 5.8e-28 96.6 0.0 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 CCM01593.1 - 0.013 15.8 0.6 1.4 9.2 0.2 3.5 2 1 0 3 3 3 0 HEAT repeats TelA PF05816.6 CCM01593.1 - 0.033 12.8 0.2 0.075 11.7 0.0 1.6 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Arm PF00514.18 CCM01593.1 - 0.086 12.6 0.1 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat FAD_binding_3 PF01494.14 CCM01594.1 - 1e-24 87.2 3.0 6.2e-15 55.0 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CCM01594.1 - 2.4e-08 33.2 1.3 1.3e-07 30.8 0.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 CCM01594.1 - 6.2e-06 25.3 0.0 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CCM01594.1 - 8.5e-06 24.6 0.2 0.0047 15.6 0.1 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Thi4 PF01946.12 CCM01594.1 - 0.00035 19.7 0.0 0.0009 18.4 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CCM01594.1 - 0.00037 20.4 0.1 0.0009 19.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCM01594.1 - 0.0004 20.1 0.1 0.002 17.9 0.1 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 CCM01594.1 - 0.00046 19.0 0.0 0.00077 18.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 CCM01594.1 - 0.0024 18.2 0.1 0.013 15.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM01594.1 - 0.0026 17.7 0.3 0.0072 16.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCM01594.1 - 0.006 16.6 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM01594.1 - 0.027 12.9 0.3 0.047 12.1 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein RRM_1 PF00076.17 CCM01595.1 - 1.1e-14 53.7 0.0 1.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM01595.1 - 5.1e-10 39.2 0.0 7.5e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM01595.1 - 0.0029 17.4 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18p PF00861.17 CCM01596.1 - 6.1e-42 142.5 0.0 1.2e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CCM01596.1 - 2.4e-34 117.7 1.6 2.4e-34 117.7 1.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF3340 PF11818.3 CCM01596.1 - 0.0095 15.8 0.8 0.018 14.9 0.3 1.7 1 1 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) MtrA PF04208.9 CCM01596.1 - 0.064 12.6 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A K_oxygenase PF13434.1 CCM01596.1 - 0.086 11.7 1.1 0.11 11.3 0.2 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Med17 PF10156.4 CCM01597.1 - 1.6e-40 138.7 0.0 2e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.13 CCM01598.1 - 1.8e-15 56.5 0.3 3.8e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Exo_endo_phos PF03372.18 CCM01599.1 - 8.9e-19 68.3 0.0 1.1e-18 68.1 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CCM01599.1 - 3.6e-05 23.3 0.0 6.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase GPI-anchored PF10342.4 CCM01600.1 - 6.9e-06 26.4 0.5 0.00043 20.7 0.3 3.3 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Snf7 PF03357.16 CCM01601.1 - 2.4e-29 101.9 21.3 2.4e-29 101.9 14.7 1.9 1 1 1 2 2 2 1 Snf7 V_ATPase_I PF01496.14 CCM01601.1 - 7.3 4.3 10.7 8.5 4.0 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Iso_dh PF00180.15 CCM01602.1 - 1.7e-98 329.8 0.0 1.9e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.14 CCM01603.1 - 6e-99 331.4 0.1 1.2e-98 330.4 0.1 1.5 1 0 0 1 1 1 1 RNB domain Rpr2 PF04032.11 CCM01604.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain BTB_2 PF02214.17 CCM01605.1 - 0.082 13.1 0.1 1.5 9.0 0.0 2.8 2 1 0 2 2 2 0 BTB/POZ domain DnaJ PF00226.26 CCM01606.1 - 9.6e-19 66.8 0.0 1.5e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.8 CCM01606.1 - 0.038 14.3 0.1 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Gln-synt_C PF00120.19 CCM01607.1 - 4.4e-62 209.5 0.0 5.3e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CCM01607.1 - 5.5e-18 64.3 0.0 9.1e-18 63.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain VID27 PF08553.5 CCM01608.1 - 8.7e-259 860.9 0.5 9.7e-259 860.8 0.3 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein NOA36 PF06524.7 CCM01608.1 - 7.8 5.6 6.9 13 4.9 4.8 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3759 PF12585.3 CCM01609.1 - 0.0012 18.6 0.2 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Nop14 PF04147.7 CCM01610.1 - 0.0061 14.5 1.4 0.0082 14.1 1.0 1.1 1 0 0 1 1 1 1 Nop14-like family RIC1 PF07064.8 CCM01611.1 - 2.3e-71 240.3 0.0 3.3e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 RIC1 DIOX_N PF14226.1 CCM01612.1 - 6.7e-05 23.3 0.0 0.00038 20.9 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM01612.1 - 0.0064 16.7 0.0 0.019 15.2 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_28 PF03033.15 CCM01613.1 - 4e-25 88.2 0.0 8.2e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CCM01613.1 - 1e-17 63.4 0.5 2.7e-09 36.3 0.0 3.5 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 CCM01613.1 - 5.4e-14 52.2 0.3 5.3e-12 45.8 0.1 3.4 3 0 0 3 3 3 1 PH domain UDPGT PF00201.13 CCM01613.1 - 3e-06 26.0 0.0 6.3e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.1 CCM01613.1 - 4e-06 27.0 0.2 0.01 16.0 0.2 3.0 2 1 1 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.1 CCM01613.1 - 0.0014 18.6 0.0 0.0046 17.0 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 CCM01613.1 - 0.02 14.9 0.1 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain SUR7 PF06687.7 CCM01614.1 - 9.4e-15 54.7 4.6 1.2e-14 54.4 3.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCM01614.1 - 1.7e-05 24.5 7.6 1.9e-05 24.4 5.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PIRT PF15099.1 CCM01614.1 - 0.32 10.2 2.7 0.56 9.4 1.8 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF2231 PF09990.4 CCM01614.1 - 1.1 9.6 8.8 1.1 9.6 4.9 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) Polysacc_deac_1 PF01522.16 CCM01615.1 - 9.3e-30 102.8 0.0 2.3e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.16 CCM01616.1 - 1.5e-06 27.8 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Peptidase_M75 PF09375.5 CCM01616.1 - 0.16 11.2 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Imelysin DUF3359 PF11839.3 CCM01617.1 - 0.0051 17.1 2.7 0.0073 16.6 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3359) NAP PF00956.13 CCM01618.1 - 6.4e-35 120.4 0.0 6.4e-35 120.4 0.0 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nucleoplasmin PF03066.10 CCM01618.1 - 0.083 12.4 3.8 0.12 11.8 2.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 CCM01618.1 - 0.13 12.4 5.8 0.41 10.8 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nro1 PF12753.2 CCM01618.1 - 0.19 10.6 2.8 0.3 9.9 1.9 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Syja_N PF02383.13 CCM01619.1 - 2.9e-87 292.4 0.0 3.6e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain LRR_9 PF14580.1 CCM01620.1 - 3e-53 179.9 0.1 9.8e-50 168.5 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.2 CCM01620.1 - 1.7e-13 49.8 11.3 4e-09 35.8 1.9 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM01620.1 - 4.5e-12 45.5 19.3 3.2e-07 29.9 6.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 CCM01620.1 - 0.00064 19.5 8.8 0.63 10.4 0.3 4.5 5 0 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 CCM01620.1 - 0.0082 16.0 12.0 0.34 11.1 0.3 4.5 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 CCM01620.1 - 0.033 14.2 8.3 0.29 11.3 0.7 3.8 2 1 1 3 3 3 0 Leucine Rich repeat DUF4149 PF13664.1 CCM01621.1 - 4.7e-23 81.1 5.1 4.7e-23 81.1 3.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Tmemb_170 PF10190.4 CCM01621.1 - 0.099 12.7 2.2 0.2 11.7 1.5 1.6 1 0 0 1 1 1 0 Putative transmembrane protein 170 DUF2628 PF10947.3 CCM01621.1 - 0.13 12.1 6.3 0.27 11.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) OPT PF03169.10 CCM01622.1 - 5.1e-177 590.0 45.8 6e-177 589.8 31.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MitMem_reg PF13012.1 CCM01623.1 - 2e-19 69.7 0.1 2.9e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CCM01623.1 - 3.2e-12 46.1 0.0 5.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MCM PF00493.18 CCM01624.1 - 6.6e-142 472.1 0.2 8.6e-142 471.8 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCM01624.1 - 1.3e-16 61.1 0.5 5.8e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCM01624.1 - 7.4e-07 28.5 0.0 0.00021 20.5 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCM01624.1 - 0.0001 22.0 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCM01624.1 - 0.00055 19.5 0.1 0.0032 17.0 0.0 2.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 CCM01624.1 - 0.0024 18.2 0.4 0.016 15.6 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 CCM01624.1 - 0.05 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2 PF00096.21 CCM01625.1 - 3.2e-09 36.5 19.6 4e-06 26.8 0.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM01625.1 - 5.8e-06 26.2 18.1 0.0002 21.4 0.4 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCM01625.1 - 0.019 15.2 0.3 0.019 15.2 0.2 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCM01625.1 - 0.4 10.8 6.1 1.5 9.0 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CCM01625.1 - 1.1 9.3 5.2 3.1 7.9 3.5 1.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Catalase PF00199.14 CCM01626.1 - 2.7e-163 543.1 0.8 4e-163 542.5 0.5 1.2 1 0 0 1 1 1 1 Catalase Med6 PF04934.9 CCM01626.1 - 3.5e-26 91.4 0.1 1.6e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 MED6 mediator sub complex component Catalase-rel PF06628.7 CCM01626.1 - 1.3e-17 63.3 0.0 3.2e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 CCM01626.1 - 1.3e-08 34.4 0.0 2.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CCM01626.1 - 0.00048 19.4 0.0 0.00085 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase Clat_adaptor_s PF01217.15 CCM01627.1 - 1.2e-40 138.5 0.1 3.7e-40 136.9 0.1 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain SelB-wing_2 PF09106.6 CCM01628.1 - 0.11 12.4 0.6 21 5.1 0.0 2.5 2 0 0 2 2 2 0 Elongation factor SelB, winged helix CBM_5_12 PF02839.9 CCM01629.1 - 9e-14 50.7 28.7 7.8e-09 34.9 6.9 3.6 3 0 0 3 3 3 3 Carbohydrate binding domain Pkinase PF00069.20 CCM01630.1 - 1.6e-59 201.1 0.1 1.9e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01630.1 - 2e-20 72.9 0.0 3e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM01630.1 - 8.8e-07 28.8 0.0 5e-05 23.1 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM01630.1 - 0.015 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 CCM01630.1 - 0.057 12.4 0.1 0.098 11.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.23 CCM01631.1 - 1.9e-06 28.2 0.0 0.00067 20.0 0.0 2.2 1 1 1 2 2 2 2 SET domain CTDII PF01556.13 CCM01632.1 - 1.1e-28 98.9 0.3 1.8e-20 72.5 0.0 3.1 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CCM01632.1 - 4.8e-24 83.8 3.8 7.8e-24 83.1 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CCM01632.1 - 1.5e-09 37.7 19.8 1.5e-09 37.7 13.7 1.8 2 0 0 2 2 2 1 DnaJ central domain Cytochrome_C7 PF14522.1 CCM01632.1 - 1.1 8.9 10.7 3.3 7.4 6.9 2.1 1 1 0 1 1 1 0 Cytochrome c7 HypA PF01155.14 CCM01632.1 - 5.4 6.7 10.1 3.4 7.3 1.0 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family MFS_1 PF07690.11 CCM01633.1 - 1.2e-33 116.2 66.8 7e-33 113.7 34.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM01633.1 - 4e-09 35.5 10.4 4e-09 35.5 7.2 3.3 4 0 0 4 4 4 2 Sugar (and other) transporter Choline_kinase PF01633.15 CCM01634.1 - 2.8e-52 177.3 0.0 3.9e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CCM01634.1 - 4e-13 49.6 0.1 7.2e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CCM01634.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3437 PF11919.3 CCM01635.1 - 6.6e-29 99.4 0.0 1.5e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) zf-CCCH PF00642.19 CCM01635.1 - 5.1e-18 64.3 13.4 5.8e-10 38.6 1.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HEAT PF02985.17 CCM01635.1 - 3e-06 26.8 1.9 0.032 14.2 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 CCM01635.1 - 0.0096 15.7 0.6 0.091 12.5 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCM01635.1 - 0.01 16.0 0.3 0.13 12.5 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats Vac14_Fab1_bd PF12755.2 CCM01635.1 - 0.25 11.7 0.1 1.1 9.7 0.0 2.0 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region TIM21 PF08294.6 CCM01637.1 - 1.2e-24 86.6 0.0 9.9e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 TIM21 ATP-synt_F PF01990.12 CCM01638.1 - 1.5e-31 108.6 0.2 1.7e-31 108.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 CCM01638.1 - 0.034 13.0 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase SGT1 PF07093.6 CCM01639.1 - 1.6e-131 439.5 22.5 4.6e-131 438.0 15.6 1.6 1 1 0 1 1 1 1 SGT1 protein Translin PF01997.11 CCM01642.1 - 3.4e-54 183.4 0.4 8.6e-54 182.1 0.1 1.9 2 0 0 2 2 2 1 Translin family DUF3437 PF11919.3 CCM01642.1 - 1.1e-08 34.6 1.7 2.1e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 CCM01642.1 - 7.2e-06 26.1 2.2 0.0037 17.4 0.0 5.0 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.17 CCM01642.1 - 8e-06 25.5 8.2 0.011 15.7 0.1 5.8 6 0 0 6 6 6 2 HEAT repeat HD_assoc PF13286.1 CCM01642.1 - 0.0011 19.1 0.0 0.012 15.8 0.0 2.7 3 0 0 3 3 3 1 Phosphohydrolase-associated domain Cnd1 PF12717.2 CCM01642.1 - 0.4 10.5 1.7 35 4.1 0.0 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ATP-grasp_2 PF08442.5 CCM01646.1 - 1.2e-73 246.8 0.9 2.3e-73 245.8 0.3 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 CCM01646.1 - 2e-26 92.4 0.1 4.3e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CCM01646.1 - 4.6e-12 45.6 0.1 2.5e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 CCM01646.1 - 0.00049 19.7 0.3 0.0066 16.0 0.0 2.5 2 1 1 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peripla_BP_2 PF01497.13 CCM01646.1 - 0.011 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein ATP-grasp_4 PF13535.1 CCM01646.1 - 0.041 13.6 0.1 0.17 11.6 0.0 1.9 2 1 0 2 2 2 0 ATP-grasp domain DinB_2 PF12867.2 CCM01647.1 - 5.3e-07 30.0 1.8 6.8e-07 29.6 1.2 1.2 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.7 CCM01647.1 - 0.00073 19.2 1.1 0.0013 18.4 0.3 1.6 1 1 1 2 2 2 1 DinB family Hist_deacetyl PF00850.14 CCM01648.1 - 3.8e-85 285.9 0.0 5.1e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain XPA_C PF05181.7 CCM01649.1 - 1.3e-18 66.3 1.5 2.5e-18 65.3 1.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus DUF4585 PF15232.1 CCM01649.1 - 0.00066 19.4 0.1 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4585) PWWP PF00855.12 CCM01649.1 - 0.062 13.4 0.7 0.062 13.4 0.5 1.9 2 0 0 2 2 2 0 PWWP domain 4HBT_3 PF13622.1 CCM01650.1 - 2.7e-36 125.6 0.0 3.5e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CCM01650.1 - 4.2e-25 87.9 0.0 4.8e-20 71.5 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase Ribosomal_S27e PF01667.12 CCM01651.1 - 3.1e-28 97.0 1.5 4.8e-28 96.4 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CCM01651.1 - 0.036 13.9 0.5 0.036 13.9 0.4 1.7 3 0 0 3 3 3 0 IBR domain BTG PF07742.7 CCM01652.1 - 1.1e-13 50.6 0.0 1.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 BTG family DUF566 PF04484.7 CCM01652.1 - 0.28 10.6 6.0 0.45 9.9 4.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pilus_PilP PF11356.3 CCM01652.1 - 1.3 9.3 4.4 3.3 8.0 0.0 2.8 3 0 0 3 3 3 0 Type IV pilus biogenesis MSA-2c PF12238.3 CCM01653.1 - 0.14 11.8 0.5 0.14 11.7 0.3 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c CD24 PF14984.1 CCM01653.1 - 0.66 9.8 5.6 1.3 8.8 3.9 1.5 1 0 0 1 1 1 0 CD24 protein BATS PF06968.8 CCM01654.1 - 6.2e-27 93.2 0.0 1.4e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CCM01654.1 - 4.2e-17 62.8 0.0 7.2e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily EF1G PF00647.14 CCM01656.1 - 3.3e-41 139.3 0.0 7.7e-41 138.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 CCM01656.1 - 1.7e-10 40.9 0.0 5.3e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM01656.1 - 2.2e-10 40.2 0.1 7.5e-10 38.5 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCM01656.1 - 2.7e-10 40.0 0.0 8.1e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCM01656.1 - 1.8e-09 37.7 0.1 4.4e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCM01656.1 - 1.4e-08 35.1 0.0 5.3e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCM01656.1 - 6.2e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Phos_pyr_kin PF08543.7 CCM01656.1 - 0.029 13.5 0.0 0.08 12.1 0.0 1.7 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase Sugar_tr PF00083.19 CCM01657.1 - 5.2e-87 292.2 31.8 1.8e-62 211.4 9.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCM01657.1 - 1.8e-08 33.4 51.7 3e-06 26.1 9.6 3.0 2 1 0 3 3 3 3 Major Facilitator Superfamily zf-RNPHF PF08080.7 CCM01657.1 - 0.064 12.7 0.3 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 RNPHF zinc finger RNase_H PF00075.19 CCM01658.1 - 0.085 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 RNase H Glyco_hydro_12 PF01670.11 CCM01661.1 - 1.5e-27 96.2 2.6 2.1e-27 95.8 1.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Epimerase PF01370.16 CCM01662.1 - 2.1e-07 30.6 0.0 6.2e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM01662.1 - 4.3e-06 26.8 0.1 7.9e-06 25.9 0.0 1.4 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 CCM01662.1 - 3e-05 23.1 0.0 4.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 CCM01662.1 - 8.8e-05 21.5 0.1 0.00042 19.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Shikimate_DH PF01488.15 CCM01662.1 - 0.00031 20.8 0.3 0.00059 19.9 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 CCM01662.1 - 0.00032 20.0 0.0 0.00048 19.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 CCM01662.1 - 0.00039 20.7 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CCM01662.1 - 0.015 14.0 0.0 0.13 10.9 0.0 2.4 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CCM01662.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 CCM01662.1 - 0.041 13.8 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.5 CCM01662.1 - 0.053 13.1 0.1 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 CCM01662.1 - 0.078 12.8 0.5 0.22 11.4 0.3 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCM01662.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-C2H2 PF00096.21 CCM01663.1 - 1.1e-06 28.6 0.3 0.023 15.0 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM01663.1 - 5.6e-05 23.1 0.3 0.43 11.0 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger MFS_1 PF07690.11 CCM01665.1 - 5.8e-43 146.9 40.3 5.8e-43 146.9 27.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM01665.1 - 9.5e-08 31.0 7.8 9.5e-08 31.0 5.4 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 CCM01665.1 - 9.2e-05 20.7 4.4 9.2e-05 20.7 3.1 2.4 2 0 0 2 2 2 1 Transmembrane secretion effector zf-C2HC5 PF06221.8 CCM01666.1 - 1.1e-13 50.6 5.6 1.8e-13 50.0 3.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Alb1 PF09135.6 CCM01667.1 - 0.97 10.0 4.6 0.58 10.7 0.8 2.4 2 0 0 2 2 2 0 Alb1 CBFB_NFYA PF02045.10 CCM01667.1 - 2.3 8.8 6.5 35 5.0 1.1 3.7 3 0 0 3 3 3 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B APH PF01636.18 CCM01669.1 - 2.7e-05 24.0 0.5 7.2e-05 22.6 0.3 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CCM01669.1 - 0.00079 18.6 0.0 0.0066 15.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain MMS22L_C PF14911.1 CCM01669.1 - 0.21 10.6 0.1 0.35 9.8 0.1 1.2 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Pkinase PF00069.20 CCM01670.1 - 0.003 16.7 0.0 0.0064 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCM01670.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family BTB PF00651.26 CCM01671.1 - 3e-18 65.8 0.0 6.2e-10 39.0 0.1 3.1 2 1 0 2 2 2 2 BTB/POZ domain FIBP PF05427.6 CCM01671.1 - 0.055 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) Helicase_C PF00271.26 CCM01673.1 - 1.4e-13 50.4 0.1 3.5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_3 PF00933.16 CCM01674.1 - 1.3e-76 257.4 0.1 2e-76 256.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCM01674.1 - 2.1e-58 197.5 1.5 2.1e-58 197.5 1.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCM01674.1 - 4.2e-18 65.0 0.0 9e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Ser_hydrolase PF06821.8 CCM01674.1 - 0.034 13.7 0.0 0.034 13.7 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Glyco_hydro_3 PF00933.16 CCM01675.1 - 7.4e-80 268.1 0.2 1.1e-79 267.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCM01675.1 - 3.6e-61 206.5 1.1 2.1e-60 204.0 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCM01675.1 - 4.5e-18 64.9 0.0 1.2e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain BTB PF00651.26 CCM01676.1 - 1.1e-12 47.9 0.0 8e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain adh_short PF00106.20 CCM01677.1 - 3.3e-16 59.6 0.5 1.2e-15 57.8 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CCM01677.1 - 1.9e-06 28.0 0.0 4.3e-06 26.8 0.0 1.5 1 1 1 2 2 2 1 NADH(P)-binding KR PF08659.5 CCM01677.1 - 3e-05 23.7 0.1 5.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM01677.1 - 0.00029 20.3 0.0 0.00054 19.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3400 PF11880.3 CCM01677.1 - 0.13 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) adh_short PF00106.20 CCM01679.1 - 5.9e-12 45.8 0.0 9.3e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CCM01679.1 - 2.1e-06 27.8 0.0 3.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Peptidase_M55 PF04951.8 CCM01679.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 D-aminopeptidase SWIB PF02201.13 CCM01680.1 - 1.4e-16 59.9 0.0 3.9e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain BAR PF03114.13 CCM01681.1 - 5.3e-34 117.7 6.5 8e-34 117.1 4.5 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CCM01681.1 - 1.3e-14 53.2 0.0 3.1e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCM01681.1 - 1.4e-14 53.3 0.0 3e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCM01681.1 - 4.4e-10 38.8 0.0 1.3e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF365 PF04033.7 CCM01681.1 - 0.045 13.7 0.2 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF365) DUF342 PF03961.8 CCM01681.1 - 0.19 10.1 1.2 0.29 9.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 CCM01681.1 - 0.35 10.4 6.2 0.7 9.4 4.3 1.5 1 0 0 1 1 1 0 IncA protein DUF4398 PF14346.1 CCM01681.1 - 9.5 6.3 18.3 0.36 10.9 5.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Glutaredoxin PF00462.19 CCM01682.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Securin PF04856.8 CCM01682.1 - 0.79 9.3 4.1 1.5 8.4 2.8 1.6 1 1 0 1 1 1 0 Securin sister-chromatid separation inhibitor p450 PF00067.17 CCM01683.1 - 1.5e-88 297.3 0.0 2.4e-88 296.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 CCM01683.1 - 2.4e-22 79.4 0.0 3.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCM01683.1 - 4.2e-20 72.1 0.0 1.4e-19 70.5 0.0 2.0 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCM01683.1 - 8.7e-10 39.1 0.0 1.7e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 CCM01683.1 - 0.004 17.0 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 CCM01683.1 - 0.018 15.0 0.0 0.051 13.5 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain DUF4296 PF14129.1 CCM01683.1 - 0.13 12.4 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) Abi PF02517.11 CCM01684.1 - 0.55 10.4 7.2 0.22 11.6 2.3 1.9 1 1 1 2 2 2 0 CAAX protease self-immunity DUF2306 PF10067.4 CCM01684.1 - 8 6.6 9.7 13 6.0 2.9 2.4 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) MFS_1 PF07690.11 CCM01685.1 - 3.5e-18 65.4 59.1 6.4e-17 61.2 23.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CCM01685.1 - 0.05 13.3 0.9 0.27 11.0 0.1 2.7 2 0 0 2 2 2 0 MFS_1 like family Pkinase PF00069.20 CCM01687.1 - 6.7e-69 231.9 0.0 9.9e-69 231.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01687.1 - 1.4e-29 102.9 0.1 1.5e-28 99.6 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM01687.1 - 1.4e-06 27.4 1.1 0.00076 18.5 0.1 3.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 CCM01687.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 CCM01688.1 - 1.4e-23 83.2 38.9 4.2e-10 38.8 7.8 3.8 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 CCM01688.1 - 8.7e-07 27.5 5.4 1.2e-05 23.7 0.3 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Ribosomal_S14 PF00253.16 CCM01689.1 - 8.9e-18 63.4 0.3 1.4e-17 62.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.3 CCM01690.1 - 2.8e-18 66.1 2.8 3.5e-16 59.3 1.3 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CCM01690.1 - 2.3e-08 33.8 3.8 2.3e-08 33.8 2.6 2.3 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CCM01690.1 - 0.0044 16.8 5.9 0.0055 16.5 1.1 2.5 2 0 0 2 2 2 1 Basic region leucine zipper HJURP_C PF12347.3 CCM01690.1 - 0.048 13.2 0.2 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat ActA PF05058.7 CCM01691.1 - 0.11 10.4 0.1 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 ActA Protein DUF4187 PF13821.1 CCM01693.1 - 5.2e-21 73.9 1.2 1.2e-20 72.8 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 CCM01693.1 - 8.3e-06 25.4 0.2 2.7e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 G-patch domain Methyltransf_20 PF12147.3 CCM01693.1 - 0.014 14.3 0.1 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase RRM_1 PF00076.17 CCM01694.1 - 5e-15 54.8 0.0 2.5e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM01694.1 - 2.1e-12 46.8 0.0 1.2e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM01694.1 - 2.8e-05 23.8 0.0 0.034 14.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Totivirus_coat PF05518.6 CCM01694.1 - 0.09 10.5 11.0 0.11 10.3 7.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein RRM_1 PF00076.17 CCM01695.1 - 0.019 14.5 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_cc PF11790.3 CCM01696.1 - 1.3e-52 178.6 0.8 1.7e-52 178.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Pex14_N PF04695.8 CCM01696.1 - 1.5 8.9 12.2 3.2 7.8 8.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 CCM01696.1 - 2.8 7.2 20.3 3.7 6.8 14.1 1.1 1 0 0 1 1 1 0 Vta1 like Spc7_N PF15402.1 CCM01696.1 - 3.8 5.4 19.2 5 5.0 13.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Ribosomal_L11 PF00298.14 CCM01698.1 - 4.2e-27 94.0 0.4 7.1e-27 93.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 CCM01698.1 - 5.1e-26 89.9 0.2 8.3e-26 89.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Peptidase_M28 PF04389.12 CCM01699.1 - 2.2e-27 95.9 0.0 3.2e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCM01699.1 - 3e-06 26.8 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 C2 PF00168.25 CCM01702.1 - 7.7e-12 44.8 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF1237 PF06824.6 CCM01703.1 - 7.7e-131 436.5 2.3 8.8e-130 433.0 1.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1237) DUF1640 PF07798.6 CCM01705.1 - 1.5e-10 41.4 2.5 1.8e-10 41.1 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ATP_bind_1 PF03029.12 CCM01706.1 - 6.1e-49 166.7 0.0 8.5e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CCM01706.1 - 1.3e-06 29.1 0.4 2.3e-06 28.4 0.3 1.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CCM01706.1 - 0.00029 19.8 0.0 0.00044 19.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein CbiA PF01656.18 CCM01706.1 - 0.00044 19.7 0.0 0.00075 18.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 CCM01706.1 - 0.00063 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CCM01706.1 - 0.00077 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ArsA_ATPase PF02374.10 CCM01706.1 - 0.0012 17.9 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_22 PF13401.1 CCM01706.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CCM01706.1 - 0.004 16.6 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 CCM01706.1 - 0.0065 16.3 2.0 0.007 16.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 CCM01706.1 - 0.0069 16.3 0.0 0.022 14.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 CCM01706.1 - 0.012 14.4 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 CCM01706.1 - 0.017 15.4 0.0 0.017 15.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.5 CCM01706.1 - 0.02 14.1 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CCM01706.1 - 0.027 13.5 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CCM01706.1 - 0.033 14.3 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 CCM01706.1 - 0.038 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Sigma54_activat PF00158.21 CCM01706.1 - 0.044 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 CCM01706.1 - 0.052 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 CCM01706.1 - 0.055 12.4 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF258 PF03193.11 CCM01706.1 - 0.073 12.2 0.1 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CCM01706.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 CCM01706.1 - 0.1 12.3 0.2 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CCM01706.1 - 0.11 12.0 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCM01706.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CCM01706.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 CCM01706.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 CCM01706.1 - 0.19 10.7 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Septin NTPase_1 PF03266.10 CCM01706.1 - 0.25 11.0 0.1 0.51 10.0 0.0 1.5 1 0 0 1 1 1 0 NTPase IIGP PF05049.8 CCM01706.1 - 0.33 9.7 0.0 0.43 9.3 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 CCM01707.1 - 1.8e-13 50.6 0.0 1.8e-13 50.6 0.0 3.5 3 1 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.13 CCM01707.1 - 2.2e-05 24.0 0.5 0.00055 19.4 0.0 3.2 4 0 0 4 4 4 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CCM01707.1 - 0.00014 21.7 2.2 0.018 15.0 1.5 3.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCM01707.1 - 0.0017 17.5 0.1 0.01 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 T2SE PF00437.15 CCM01707.1 - 0.0061 15.5 0.1 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 CCM01707.1 - 0.015 15.3 0.0 0.19 11.6 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CCM01707.1 - 0.024 14.7 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCM01707.1 - 0.039 14.2 0.2 0.039 14.2 0.2 2.6 2 2 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 CCM01707.1 - 0.045 13.2 0.2 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 CCM01707.1 - 0.097 12.4 0.1 0.097 12.4 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function DUF87 MFS_1 PF07690.11 CCM01709.1 - 8.5e-33 113.5 20.5 1.1e-32 113.1 14.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ldr_toxin PF13940.1 CCM01709.1 - 0.076 12.7 0.4 0.076 12.7 0.3 2.2 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system HTH_23 PF13384.1 CCM01709.1 - 0.088 12.4 0.1 0.71 9.6 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain VirArc_Nuclease PF12187.3 CCM01709.1 - 0.12 11.7 0.4 6.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Viral/Archaeal nuclease Snf7 PF03357.16 CCM01710.1 - 9.8e-45 151.9 12.2 1.2e-44 151.7 8.5 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 CCM01710.1 - 0.0052 16.5 9.5 1.1 9.0 0.0 3.5 2 1 1 3 3 3 1 Prefoldin subunit NPV_P10 PF05531.7 CCM01710.1 - 0.0073 16.5 0.3 0.39 11.0 0.1 2.6 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF1569 PF07606.6 CCM01710.1 - 0.031 14.2 0.3 0.049 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) NuA4 PF09340.5 CCM01710.1 - 0.14 11.7 0.7 0.41 10.3 0.3 2.0 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 FlaC_arch PF05377.6 CCM01710.1 - 0.17 11.8 2.9 11 5.9 0.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 CCM01710.1 - 0.2 11.3 10.3 1.7 8.2 7.0 2.1 1 1 0 1 1 1 0 Mnd1 family Prefoldin PF02996.12 CCM01710.1 - 0.38 10.4 8.4 0.81 9.3 0.0 3.4 2 1 0 2 2 2 0 Prefoldin subunit DUF3091 PF11291.3 CCM01710.1 - 0.46 10.4 3.1 0.6 10.0 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3091) DUF2730 PF10805.3 CCM01710.1 - 0.57 9.9 5.4 1.2 8.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF342 PF03961.8 CCM01710.1 - 0.63 8.3 8.8 0.22 9.8 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Phage_GP20 PF06810.6 CCM01710.1 - 0.71 9.3 15.7 1.5 8.2 6.7 2.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4559 PF15112.1 CCM01710.1 - 1.2 8.1 7.2 2.5 7.1 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) FlxA PF14282.1 CCM01710.1 - 2.8 7.9 11.3 2.9 7.8 4.4 2.5 1 1 2 3 3 3 0 FlxA-like protein IncA PF04156.9 CCM01710.1 - 7.6 6.0 10.2 1.8 8.1 1.8 2.5 1 1 1 2 2 2 0 IncA protein Aldedh PF00171.17 CCM01711.1 - 5.5e-150 499.7 0.1 6.6e-150 499.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCM01711.1 - 0.00012 21.0 0.7 0.001 17.8 0.5 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Abhydrolase_1 PF00561.15 CCM01712.1 - 3.2e-18 66.1 0.0 5.1e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCM01712.1 - 6.4e-13 49.1 1.5 5.9e-11 42.6 1.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CCM01712.1 - 0.00057 19.3 0.1 0.00099 18.6 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Snf7 PF03357.16 CCM01714.1 - 1.3e-18 66.9 14.8 1.6e-18 66.7 10.3 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 CCM01714.1 - 0.017 14.5 5.4 0.03 13.7 3.8 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF1053 PF06327.9 CCM01714.1 - 0.18 12.1 3.4 2.4 8.5 0.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) DUF724 PF05266.9 CCM01714.1 - 0.89 9.1 9.5 0.048 13.2 0.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) TBCA PF02970.11 CCM01714.1 - 1.5 8.9 11.5 1.2 9.2 1.2 2.6 2 1 0 2 2 2 0 Tubulin binding cofactor A MUG113 PF13455.1 CCM01715.1 - 2.8e-15 56.5 0.2 3.5e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 CCM01715.1 - 3.8e-09 36.8 0.3 8e-08 32.5 0.2 2.7 1 1 0 1 1 1 1 T5orf172 domain LON PF02190.11 CCM01716.1 - 4.8e-14 52.5 0.0 1.1e-13 51.3 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 CCM01717.1 - 0.0015 18.3 10.2 0.015 15.1 1.9 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCM01717.1 - 0.021 14.5 9.5 0.47 10.2 1.9 2.9 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCM01717.1 - 0.35 10.9 15.4 0.24 11.4 1.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCM01717.1 - 0.38 10.4 12.1 0.28 10.8 1.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCM01717.1 - 3 7.7 13.6 3.6 7.5 1.3 3.3 2 1 1 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.1 CCM01717.1 - 3.3 7.5 15.0 0.43 10.3 2.6 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Amidohydro_2 PF04909.9 CCM01718.1 - 3.2e-09 36.7 0.8 5.6e-09 35.9 0.6 1.6 1 1 0 1 1 1 1 Amidohydrolase Kinesin PF00225.18 CCM01719.1 - 1.5e-105 352.5 0.0 2.8e-105 351.7 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Eapp_C PF10238.4 CCM01719.1 - 0.25 11.2 1.3 0.61 9.9 0.9 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein VSG_B PF13206.1 CCM01719.1 - 0.48 9.5 11.5 0.26 10.3 6.5 1.5 1 1 0 1 1 1 0 Trypanosomal VSG domain BTV_NS2 PF04514.7 CCM01719.1 - 0.62 8.8 7.0 0.9 8.3 4.3 1.6 1 1 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DivIVA PF05103.8 CCM01719.1 - 6.6 6.7 16.4 0.36 10.8 4.9 2.7 1 1 0 2 2 2 0 DivIVA protein EMP24_GP25L PF01105.19 CCM01720.1 - 1.1e-51 175.1 0.1 1.3e-51 174.8 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PPC PF04151.10 CCM01720.1 - 0.051 14.5 0.0 0.11 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Ran_BP1 PF00638.13 CCM01721.1 - 2.8e-50 169.4 0.6 4.1e-50 168.9 0.4 1.2 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 CCM01721.1 - 1.2e-05 24.9 0.5 1.5e-05 24.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 CCM01721.1 - 8e-05 22.3 0.6 0.00055 19.6 0.4 1.9 1 1 0 1 1 1 1 WH1 domain AAA_2 PF07724.9 CCM01722.1 - 5.7e-39 133.7 0.0 9.5e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCM01722.1 - 1.1e-14 54.7 0.0 2.2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CCM01722.1 - 3.9e-10 39.4 0.0 7.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CCM01722.1 - 3.7e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCM01722.1 - 5.5e-05 23.9 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCM01722.1 - 0.00014 21.9 0.1 0.0025 17.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCM01722.1 - 0.00016 20.8 0.0 0.0043 16.2 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CCM01722.1 - 0.0004 20.4 0.0 0.00088 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 CCM01722.1 - 0.0015 17.4 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 CCM01722.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCM01722.1 - 0.0031 16.9 0.1 0.0092 15.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 CCM01722.1 - 0.0072 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CCM01722.1 - 0.0076 15.7 0.0 0.098 12.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 CCM01722.1 - 0.0083 15.1 0.0 0.083 11.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCM01722.1 - 0.0099 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CCM01722.1 - 0.011 15.2 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.1 CCM01722.1 - 0.011 15.7 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 CCM01722.1 - 0.015 15.4 0.0 0.11 12.6 0.0 2.4 2 1 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 CCM01722.1 - 0.016 14.6 0.0 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.11 CCM01722.1 - 0.019 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 CCM01722.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CCM01722.1 - 0.023 14.3 0.0 0.67 9.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CCM01722.1 - 0.032 13.9 0.7 0.057 13.1 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain ABC_tran PF00005.22 CCM01722.1 - 0.033 14.4 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 CCM01722.1 - 0.04 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 CCM01722.1 - 0.054 13.0 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CCM01722.1 - 0.099 12.0 0.1 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 CCM01722.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CCM01722.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 CCM01722.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MCM PF00493.18 CCM01722.1 - 0.23 10.1 0.0 0.64 8.7 0.0 1.7 1 1 0 1 1 1 0 MCM2/3/5 family Cactin_mid PF10312.4 CCM01723.1 - 3.7e-61 205.7 7.1 3.7e-61 205.7 4.9 1.8 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.4 CCM01723.1 - 5.6e-58 193.9 6.0 1.5e-57 192.6 4.2 1.8 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein tRNA-synt_2d PF01409.15 CCM01724.1 - 0.065 12.4 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF2370 PF10176.4 CCM01725.1 - 3.1e-70 236.1 0.0 3.1e-70 236.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) Peptidase_M48 PF01435.13 CCM01726.1 - 0.032 13.8 17.9 3.5 7.1 1.2 4.9 1 1 3 4 4 4 0 Peptidase family M48 Jacalin PF01419.12 CCM01726.1 - 8 6.3 27.9 8.9 6.2 0.7 5.7 1 1 2 5 5 5 0 Jacalin-like lectin domain DUF3328 PF11807.3 CCM01727.1 - 4.9e-52 176.7 0.2 5.7e-52 176.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 CCM01728.1 - 7.8e-62 208.7 0.8 1e-61 208.4 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Bclx_interact PF08945.5 CCM01729.1 - 0.021 14.3 6.5 0.33 10.5 0.5 2.3 1 1 1 2 2 2 0 Bcl-x interacting, BH3 domain DUF4395 PF14340.1 CCM01729.1 - 0.065 13.3 0.1 0.087 12.8 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) DDE_Tnp_IS66_C PF13817.1 CCM01729.1 - 0.12 12.4 0.6 28 4.8 0.0 2.8 3 0 0 3 3 3 0 IS66 C-terminal element Calreticulin PF00262.13 CCM01729.1 - 0.17 10.4 0.7 0.21 10.2 0.5 1.0 1 0 0 1 1 1 0 Calreticulin family DUF3487 PF11990.3 CCM01729.1 - 0.43 9.9 3.8 10 5.5 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) Nbs1_C PF08599.5 CCM01729.1 - 0.81 9.6 5.2 27 4.7 3.7 2.3 1 1 0 1 1 1 0 DNA damage repair protein Nbs1 PepSY_2 PF13670.1 CCM01730.1 - 0.014 15.3 0.8 0.47 10.3 0.1 2.1 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain DsrH PF04077.7 CCM01730.1 - 0.18 11.5 1.5 65 3.2 0.0 3.0 1 1 2 3 3 3 0 DsrH like protein IGPS PF00218.16 CCM01731.1 - 4e-92 307.8 0.0 8.9e-92 306.7 0.0 1.5 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 CCM01731.1 - 8.8e-54 182.0 0.0 5.1e-48 163.2 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 CCM01731.1 - 2.3e-50 170.7 0.0 3.7e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCM01731.1 - 7.6e-08 32.0 0.0 2.1e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.14 CCM01731.1 - 0.0054 16.2 1.6 2 7.9 0.0 3.9 5 0 0 5 5 5 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 CCM01731.1 - 0.051 12.5 0.1 0.34 9.8 0.0 2.2 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 CCM01731.1 - 0.055 12.7 0.1 0.37 10.0 0.0 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.9 CCM01731.1 - 0.058 12.4 0.0 2.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DER1 PF04511.10 CCM01733.1 - 2.3e-06 27.2 4.9 3.4e-06 26.6 3.4 1.2 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 CCM01733.1 - 3.1e-05 24.2 0.3 5.8e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 CCM01733.1 - 0.00063 19.7 7.0 0.00063 19.7 4.9 1.5 2 0 0 2 2 2 1 Rhomboid family CUE PF02845.11 CCM01733.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain eIF-3_zeta PF05091.7 CCM01734.1 - 2.8e-183 610.2 0.0 3.5e-183 609.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.17 CCM01735.1 - 9.8e-18 63.5 0.0 1.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM01735.1 - 1.3e-11 44.2 0.0 2.2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM01735.1 - 2.1e-07 30.6 0.0 3.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YihI PF04220.7 CCM01735.1 - 0.1 11.9 13.7 0.078 12.2 8.3 1.7 1 1 0 1 1 1 0 Der GTPase activator (YihI) Beta_helix PF13229.1 CCM01736.1 - 6.6e-08 32.4 34.2 2.6e-06 27.3 21.5 3.1 1 1 1 2 2 2 2 Right handed beta helix region Disaggr_assoc PF08480.5 CCM01736.1 - 0.005 16.3 14.1 0.18 11.2 2.9 3.4 1 1 2 3 3 3 3 Disaggregatase related PAP_central PF04928.12 CCM01737.1 - 5e-107 356.4 0.0 6.7e-107 356.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CCM01737.1 - 1.5e-43 147.9 0.0 2.4e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CCM01737.1 - 4e-10 39.8 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 CCM01737.1 - 0.026 12.0 0.1 0.057 10.9 0.0 1.5 2 0 0 2 2 2 0 Nrap protein GatB_N PF02934.10 CCM01738.1 - 1.7e-109 365.1 0.0 2.3e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CCM01738.1 - 2.2e-31 108.5 0.0 3.5e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 GatB domain Thioredoxin_4 PF13462.1 CCM01739.1 - 1.2e-11 44.9 0.0 2e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 CCM01739.1 - 0.01 15.4 0.8 0.44 10.0 0.0 2.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain MCE PF02470.15 CCM01739.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 mce related protein PCI PF01399.22 CCM01740.1 - 3.7e-13 49.7 0.0 8e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain VWA_2 PF13519.1 CCM01741.1 - 2.8e-08 34.0 0.0 1.6e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CCM01741.1 - 4.1e-07 29.8 0.0 1.8e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain CobT_C PF11775.3 CCM01741.1 - 0.097 12.0 0.0 6.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain Spc97_Spc98 PF04130.8 CCM01742.1 - 1.5e-60 205.0 0.1 2.8e-60 204.1 0.0 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family Ribul_P_3_epim PF00834.14 CCM01742.1 - 0.064 12.3 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Mgm101p PF06420.7 CCM01743.1 - 1.2e-90 301.3 0.0 1.6e-90 301.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Peptidase_S10 PF00450.17 CCM01745.1 - 4.7e-98 329.0 0.0 6e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_gE PF02480.11 CCM01745.1 - 0.00064 18.1 0.0 0.00099 17.4 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E stn_TNFRSF12A PF12191.3 CCM01745.1 - 0.12 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DASH_Spc19 PF08287.6 CCM01746.1 - 5.3e-21 74.8 6.6 6.7e-20 71.2 4.6 2.2 1 1 0 1 1 1 1 Spc19 HALZ PF02183.13 CCM01746.1 - 0.066 12.9 1.3 0.18 11.5 0.9 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper AAA_13 PF13166.1 CCM01746.1 - 0.1 11.0 0.7 0.12 10.7 0.5 1.0 1 0 0 1 1 1 0 AAA domain MCM_N PF14551.1 CCM01746.1 - 0.25 11.8 1.1 0.52 10.7 0.2 1.9 1 1 1 2 2 2 0 MCM N-terminal domain MoCF_biosynth PF00994.19 CCM01747.1 - 1.6e-58 196.1 0.2 1.3e-28 99.2 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 CCM01747.1 - 2.9e-33 114.5 0.1 4.4e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 CCM01747.1 - 6e-13 48.5 0.1 1.4e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) GDPD PF03009.12 CCM01748.1 - 7.7e-32 110.7 0.1 1.5e-31 109.8 0.1 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CCM01748.1 - 6.5e-05 23.0 1.4 0.0003 20.8 0.9 2.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Toxin_51 PF15531.1 CCM01748.1 - 0.041 13.6 0.1 1.7 8.4 0.0 2.3 1 1 1 2 2 2 0 Putative toxin 51 Acyltransferase PF01553.16 CCM01751.1 - 3.7e-36 123.4 0.0 5.3e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Amidohydro_1 PF01979.15 CCM01752.1 - 4.2e-24 85.8 0.6 4.4e-23 82.4 0.4 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CCM01752.1 - 3.8e-14 52.2 0.3 9.8e-14 50.9 0.2 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CCM01752.1 - 5.6e-13 49.5 0.0 8.6e-07 29.2 0.0 2.5 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 CCM01752.1 - 2.5e-09 36.8 0.1 1e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family D-aminoacyl_C PF07908.7 CCM01752.1 - 0.024 13.9 0.3 0.059 12.6 0.2 1.6 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region Na_H_Exchanger PF00999.16 CCM01754.1 - 4.3e-58 196.6 50.6 6e-58 196.1 35.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family G10 PF01125.12 CCM01754.1 - 7.8e-47 158.4 1.1 1.2e-46 157.8 0.8 1.2 1 0 0 1 1 1 1 G10 protein TB2_DP1_HVA22 PF03134.14 CCM01755.1 - 1.1e-08 34.6 0.2 1.9e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GMC_oxred_N PF00732.14 CCM01756.1 - 8.2e-55 186.0 0.0 1.1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM01756.1 - 8.8e-36 123.3 0.0 1.5e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM01756.1 - 0.00017 20.5 0.0 0.00045 19.2 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCM01756.1 - 0.00067 18.6 0.1 0.0036 16.2 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CCM01756.1 - 0.0019 18.1 0.1 0.0052 16.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CCM01756.1 - 0.0037 16.2 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CCM01756.1 - 0.0067 16.3 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM01756.1 - 0.013 13.9 0.1 0.34 9.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 CCM01756.1 - 0.12 11.4 0.2 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family GMC_oxred_N PF00732.14 CCM01757.1 - 1.2e-44 152.6 0.0 1.8e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM01757.1 - 1.6e-31 109.5 0.0 2.7e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM01757.1 - 0.00098 18.1 0.1 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCM01757.1 - 0.0013 18.7 0.3 0.0029 17.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCM01757.1 - 0.0028 16.5 0.2 0.0041 16.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCM01757.1 - 0.01 15.7 0.0 0.034 14.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM01757.1 - 0.027 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CCM01757.1 - 0.043 13.8 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM01757.1 - 0.078 11.4 0.0 0.13 10.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Myb_DNA-bind_6 PF13921.1 CCM01759.1 - 2.1e-05 24.5 0.1 5.3e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCM01759.1 - 6.9e-05 22.8 0.0 0.00018 21.4 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Lip_prot_lig_C PF10437.4 CCM01759.1 - 0.036 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus DUF498 PF04430.9 CCM01760.1 - 1.7e-32 111.2 0.0 2.1e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) LigT_PEase PF02834.11 CCM01761.1 - 0.062 13.2 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 LigT like Phosphoesterase CHCH PF06747.8 CCM01762.1 - 0.00015 21.5 14.2 0.00022 21.0 4.8 2.4 2 0 0 2 2 2 2 CHCH domain DUF202 PF02656.10 CCM01763.1 - 1.3e-13 50.9 2.1 1.3e-13 50.9 1.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TctB PF07331.6 CCM01763.1 - 0.024 14.3 3.5 0.058 13.0 0.5 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family 7tm_6 PF02949.15 CCM01763.1 - 0.14 10.9 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 7tm Odorant receptor DUF2530 PF10745.4 CCM01763.1 - 3.6 7.6 9.1 4.4 7.3 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) THOC7 PF05615.8 CCM01764.1 - 3.9e-21 75.7 3.2 3.9e-21 75.7 2.2 1.6 1 1 0 1 1 1 1 Tho complex subunit 7 DUF3355 PF11835.3 CCM01764.1 - 1.5 8.6 7.8 0.18 11.5 0.4 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3355) LsmAD PF06741.8 CCM01764.1 - 6.6 6.9 9.0 0.62 10.2 1.3 2.6 2 0 0 2 2 2 0 LsmAD domain Lactamase_B_2 PF12706.2 CCM01765.1 - 2e-21 76.4 0.0 3.3e-21 75.7 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCM01765.1 - 5.3e-09 36.0 2.0 2e-08 34.1 0.1 2.3 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 CCM01765.1 - 4.1e-07 29.3 0.0 7.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.10 CCM01765.1 - 0.011 14.7 0.1 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Nucleoplasmin PF03066.10 CCM01766.1 - 0.038 13.5 4.2 0.068 12.6 2.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF2656 PF10847.3 CCM01766.1 - 0.29 11.0 3.4 0.55 10.1 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) CDK2AP PF09806.4 CCM01766.1 - 0.92 9.7 13.4 1.9 8.6 9.3 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein NOA36 PF06524.7 CCM01766.1 - 7.8 5.6 6.1 11 5.1 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3602 PF12223.3 CCM01766.1 - 8.2 6.8 8.9 4.7 7.6 3.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) DUF4515 PF14988.1 CCM01767.1 - 0.035 13.7 1.6 0.087 12.4 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DGF-1_C PF11040.3 CCM01767.1 - 0.057 13.2 0.1 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Ribosomal_L29 PF00831.18 CCM01769.1 - 4.5e-18 64.6 2.8 4.5e-18 64.6 1.9 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.8 CCM01769.1 - 0.024 14.5 2.4 0.028 14.3 0.6 1.8 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) MitMem_reg PF13012.1 CCM01769.1 - 0.028 14.4 3.6 0.04 13.9 0.1 2.3 1 1 2 3 3 3 0 Maintenance of mitochondrial structure and function Ribosomal_S9 PF00380.14 CCM01769.1 - 0.072 13.3 2.6 0.11 12.7 1.8 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Annexin PF00191.15 CCM01769.1 - 0.12 12.3 1.8 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Annexin CCDC-167 PF15188.1 CCM01769.1 - 0.32 10.9 5.0 0.62 10.0 0.8 2.2 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Prefoldin PF02996.12 CCM01769.1 - 1.5 8.4 7.4 17 5.1 1.1 2.9 3 0 0 3 3 3 0 Prefoldin subunit PRKCSH-like PF12999.2 CCM01769.1 - 1.9 8.0 5.3 1.1 8.8 1.0 1.9 1 1 1 2 2 2 0 Glucosidase II beta subunit-like Fib_alpha PF08702.5 CCM01769.1 - 4.5 7.3 8.5 18 5.4 5.9 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4208 PF13907.1 CCM01769.1 - 7.6 6.8 7.9 10 6.4 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) DUF607 PF04678.8 CCM01769.1 - 7.8 6.3 7.9 59 3.5 5.5 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF607 Tetraspannin PF00335.15 CCM01771.1 - 1.3e-05 24.6 19.5 1.8e-05 24.1 9.4 2.1 1 1 1 2 2 2 2 Tetraspanin family DUF202 PF02656.10 CCM01771.1 - 0.00043 20.4 8.3 0.0022 18.1 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DctQ PF04290.7 CCM01771.1 - 0.0041 16.8 7.9 3.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Tripartite ATP-independent periplasmic transporters, DctQ component Phage_holin_1 PF04531.8 CCM01771.1 - 0.19 11.7 3.9 4.4 7.4 0.9 2.4 2 0 0 2 2 2 0 Bacteriophage holin DUF3357 PF11837.3 CCM01771.1 - 2.4 8.0 4.3 16 5.4 0.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) DUF1129 PF06570.6 CCM01771.1 - 5.3 6.3 7.3 1.1 8.4 2.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Hydrophobin PF01185.13 CCM01772.1 - 5.1e-12 46.0 6.7 7.7e-12 45.4 4.7 1.3 1 0 0 1 1 1 1 Fungal hydrophobin DUF3580 PF12117.3 CCM01772.1 - 0.041 13.8 2.1 0.061 13.2 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Toxin_22 PF08092.6 CCM01772.1 - 6.7 6.6 6.7 9.9 6.0 0.7 2.2 2 0 0 2 2 2 0 Magi peptide toxin family PHD PF00628.24 CCM01773.1 - 1.9e-07 30.6 1.1 1.9e-07 30.6 0.8 3.8 5 0 0 5 5 5 1 PHD-finger ADH_N PF08240.7 CCM01773.1 - 0.075 12.7 1.4 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Hydantoinase_B PF02538.9 CCM01774.1 - 2.4e-183 610.1 0.1 2.2e-182 606.9 0.1 1.9 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF1744 PF08490.7 CCM01776.1 - 1.1e-109 366.6 0.0 1.6e-109 366.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CCM01776.1 - 3.9e-64 216.5 0.0 7.2e-64 215.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CCM01776.1 - 6.9e-19 67.9 0.0 2.1e-18 66.3 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CCM01776.1 - 1.8e-08 34.2 0.7 7.2e-08 32.2 0.1 2.2 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CCM01776.1 - 0.00057 19.7 0.0 0.0023 17.7 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily Pex24p PF06398.6 CCM01777.1 - 2.3 6.9 7.1 3.5 6.3 5.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Acetyltransf_7 PF13508.1 CCM01778.1 - 4.6e-05 23.4 1.7 0.008 16.3 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM01778.1 - 0.00018 21.4 0.5 0.0033 17.4 0.3 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family MAP65_ASE1 PF03999.7 CCM01779.1 - 5e-67 226.9 3.0 2.4e-63 214.7 0.0 2.4 2 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) FlxA PF14282.1 CCM01779.1 - 0.052 13.4 3.2 0.15 12.0 2.2 1.8 1 0 0 1 1 1 0 FlxA-like protein Histone_HNS PF00816.16 CCM01779.1 - 0.59 10.6 4.4 4.5 7.8 0.2 3.3 3 0 0 3 3 3 0 H-NS histone family Mucin PF01456.12 CCM01780.1 - 0.045 13.5 13.2 0.084 12.6 9.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Herpes_capsid PF06112.6 CCM01780.1 - 2.8 7.9 15.2 4.1 7.4 10.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Laminin_G_3 PF13385.1 CCM01781.1 - 8.7e-08 32.5 0.0 1.8e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Beach PF02138.13 CCM01782.1 - 2.3e-97 325.6 0.0 3e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 CCM01782.1 - 1.8e-14 52.9 10.4 0.00014 21.6 1.4 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat PH_BEACH PF14844.1 CCM01782.1 - 9.9e-08 31.7 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH F-box PF00646.28 CCM01783.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain Methyltransf_11 PF08241.7 CCM01784.1 - 6.2e-14 52.2 0.0 1.3e-09 38.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CCM01784.1 - 2.4e-10 40.9 0.0 4.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM01784.1 - 2e-08 34.5 0.0 5e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM01784.1 - 3.1e-07 30.1 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM01784.1 - 2.3e-06 27.4 0.0 1.3e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM01784.1 - 2.5e-06 27.5 0.0 9.2e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM01784.1 - 4.1e-06 27.1 0.0 2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM01784.1 - 3.2e-05 23.1 0.0 0.00036 19.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CCM01784.1 - 0.037 13.3 0.0 0.86 8.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.12 CCM01784.1 - 0.069 12.1 0.0 0.14 11.1 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase FtsX PF02687.16 CCM01785.1 - 0.011 15.4 1.9 0.011 15.4 1.3 2.7 2 1 1 3 3 3 0 FtsX-like permease family DUF4064 PF13273.1 CCM01785.1 - 0.11 12.6 4.2 0.13 12.3 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF3357 PF11837.3 CCM01785.1 - 4.5 7.1 7.1 18 5.2 0.1 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF3357) PMI_typeI PF01238.16 CCM01786.1 - 5.6e-102 341.4 0.0 9e-102 340.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomannose isomerase type I p450 PF00067.17 CCM01786.1 - 4.5e-54 183.7 0.0 6.8e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 CCM01786.1 - 4.4e-08 32.5 0.0 0.00038 19.8 0.0 2.7 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 CCM01786.1 - 0.0022 17.6 0.0 2.5 7.8 0.0 2.8 3 0 0 3 3 3 2 AraC-like ligand binding domain p450 PF00067.17 CCM01787.1 - 3.1e-51 174.3 0.0 3.8e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TIM PF00121.13 CCM01790.1 - 6e-86 287.4 0.6 3.3e-80 268.6 0.1 2.0 2 0 0 2 2 2 2 Triosephosphate isomerase CutC PF03932.9 CCM01790.1 - 0.097 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 CutC family tRNA-synt_2b PF00587.20 CCM01791.1 - 3.2e-15 56.1 0.0 3.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) 2OG-FeII_Oxy PF03171.15 CCM01792.1 - 1.1e-12 48.1 0.0 2.5e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CCM01793.1 - 6e-12 45.7 0.0 1.4e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CCM01793.1 - 2.7e-09 37.5 0.0 6.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CPSase_L_D2 PF02786.12 CCM01794.1 - 2.2e-115 383.2 0.1 7e-84 280.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CCM01794.1 - 2e-43 147.0 0.1 4e-43 146.0 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.23 CCM01794.1 - 2.3e-43 147.8 0.0 5e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 CCM01794.1 - 6.6e-43 145.7 0.0 1.5e-42 144.6 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 CCM01794.1 - 5.2e-41 139.2 0.0 2.1e-19 69.6 0.0 3.5 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 CCM01794.1 - 6.5e-37 126.8 0.0 3.5e-36 124.4 0.0 2.3 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 CCM01794.1 - 3.9e-36 124.5 0.1 6.5e-23 81.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCM01794.1 - 6.7e-23 80.9 0.0 3.7e-10 39.0 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 CCM01794.1 - 1e-19 70.2 0.0 4e-19 68.3 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.17 CCM01794.1 - 3.4e-17 62.3 0.1 1.7e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCM01794.1 - 1.4e-16 60.5 0.2 7e-09 35.3 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CCM01794.1 - 2.1e-07 30.9 0.1 0.0035 17.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 CCM01794.1 - 5.5e-06 25.9 0.0 0.00016 21.1 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 CCM01794.1 - 1.8e-05 24.2 0.0 0.004 16.6 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.19 CCM01794.1 - 0.00083 18.8 0.0 0.0023 17.4 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 CCM01794.1 - 0.01 15.4 0.1 0.099 12.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 CCM01794.1 - 0.054 12.7 0.0 1.2 8.3 0.1 2.3 2 0 0 2 2 2 0 ATP-grasp domain DUF1707 PF08044.6 CCM01794.1 - 1.3 8.8 4.2 2.4 7.9 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) ADH_zinc_N PF00107.21 CCM01795.1 - 1.1e-13 50.8 0.0 2.1e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM01795.1 - 4.9e-06 26.2 1.0 1.7e-05 24.5 0.7 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain EMP24_GP25L PF01105.19 CCM01796.1 - 3.2e-34 118.2 0.0 4.5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Brix PF04427.13 CCM01797.1 - 1.5e-41 142.1 0.1 2.2e-41 141.6 0.1 1.2 1 0 0 1 1 1 1 Brix domain Herpes_UL25 PF01499.11 CCM01797.1 - 0.019 13.3 0.6 0.027 12.7 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1730 PF08331.5 CCM01797.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) F-box PF00646.28 CCM01798.1 - 0.00056 19.4 1.8 0.0009 18.8 0.1 2.2 2 0 0 2 2 2 1 F-box domain Far-17a_AIG1 PF04750.9 CCM01798.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein AA_permease_2 PF13520.1 CCM01799.1 - 1.4e-54 185.2 55.2 1.8e-54 184.9 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCM01799.1 - 4.5e-13 48.3 44.7 7.2e-13 47.6 31.0 1.3 1 1 0 1 1 1 1 Amino acid permease WD40 PF00400.27 CCM01801.1 - 1.3e-09 37.5 4.6 0.42 10.5 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat DnaJ PF00226.26 CCM01803.1 - 3.8e-25 87.3 0.7 7e-25 86.5 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 CCM01803.1 - 4.5e-14 52.6 0.0 1.3e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Kri1 PF05178.7 CCM01803.1 - 0.8 10.0 2.9 6.1 7.1 0.0 2.3 2 0 0 2 2 2 0 KRI1-like family Period_C PF12114.3 CCM01803.1 - 4.8 6.7 8.0 11 5.5 5.6 1.6 1 0 0 1 1 1 0 Period protein 2/3C-terminal region F-box-like PF12937.2 CCM01804.1 - 1e-07 31.5 0.0 2.6e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM01804.1 - 7.6e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 CCM01804.1 - 0.00042 20.1 0.0 0.00089 19.0 0.0 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 CCM01804.1 - 0.043 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 CCM01804.1 - 0.07 12.7 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat KAR9 PF08580.5 CCM01805.1 - 3.3e-07 28.9 56.5 3.3e-07 28.9 39.2 4.1 2 2 0 3 3 3 2 Yeast cortical protein KAR9 DUF3829 PF12889.2 CCM01805.1 - 0.04 13.1 0.2 0.068 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Mnd1 PF03962.10 CCM01805.1 - 3.8 7.1 7.8 3 7.4 2.5 2.6 2 1 0 2 2 2 0 Mnd1 family Clr2 PF10383.4 CCM01806.1 - 0.0006 19.8 0.0 0.025 14.5 0.0 2.7 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 TPR_11 PF13414.1 CCM01807.1 - 4.4e-07 29.4 0.0 1.7e-05 24.3 0.0 1.6 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 CCM01807.1 - 2.1e-06 28.2 0.4 3.5e-06 27.5 0.0 1.6 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCM01807.1 - 2.5e-06 27.7 0.1 0.00012 22.2 0.0 1.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM01807.1 - 7.6e-06 26.1 1.3 0.053 14.1 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCM01807.1 - 0.00054 19.6 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCM01807.1 - 0.0023 17.9 0.2 0.29 11.4 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCM01807.1 - 0.02 14.8 0.0 0.064 13.2 0.0 1.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCM01807.1 - 0.02 14.6 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCM01807.1 - 0.021 15.2 0.0 5 7.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 CCM01807.1 - 0.033 14.1 2.1 0.043 13.7 1.4 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Transglut_prok PF09017.5 CCM01807.1 - 0.1 11.6 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Microbial transglutaminase TPR_20 PF14561.1 CCM01807.1 - 0.12 12.5 0.2 0.33 11.1 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat Vps5 PF09325.5 CCM01808.1 - 1.6e-66 223.9 4.1 2.1e-66 223.5 2.9 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CCM01808.1 - 2.3e-27 95.0 0.8 3.7e-26 91.1 0.1 2.3 2 0 0 2 2 2 1 PX domain BAR PF03114.13 CCM01808.1 - 6.3e-06 25.8 1.0 1e-05 25.1 0.7 1.2 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 CCM01808.1 - 0.00084 18.7 1.3 0.0063 15.8 0.9 2.0 1 1 0 1 1 1 1 Arfaptin-like domain DNA_pack_N PF02500.10 CCM01808.1 - 0.0071 15.9 0.2 0.019 14.4 0.1 1.7 2 0 0 2 2 2 1 Probable DNA packing protein, N-terminus BAR_3_WASP_bdg PF10456.4 CCM01808.1 - 0.017 14.4 0.2 0.087 12.0 0.1 2.0 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein FAM92 PF06730.6 CCM01808.1 - 0.03 13.6 2.7 0.086 12.1 1.9 1.8 1 1 0 1 1 1 0 FAM92 protein DUF2764 PF10962.3 CCM01808.1 - 0.087 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) DWNN PF08783.6 CCM01809.1 - 3.4e-24 84.5 0.1 8.7e-24 83.2 0.1 1.7 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_2 PF13923.1 CCM01809.1 - 0.00042 20.2 8.3 0.00077 19.4 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCM01809.1 - 0.011 15.5 6.3 0.023 14.4 4.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 CCM01809.1 - 0.012 15.2 4.7 0.022 14.4 3.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_2 PF13696.1 CCM01809.1 - 0.037 13.5 0.1 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle Rtf2 PF04641.7 CCM01809.1 - 0.21 10.7 2.2 0.35 10.0 1.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_5 PF14634.1 CCM01809.1 - 0.22 11.2 6.4 0.43 10.3 4.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CCM01809.1 - 0.64 9.7 8.4 1.2 8.8 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ERG4_ERG24 PF01222.12 CCM01810.1 - 9e-130 433.0 22.6 1e-129 432.8 15.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 CCM01810.1 - 0.0019 18.3 4.2 0.033 14.4 0.0 3.5 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM01810.1 - 0.0074 16.3 0.3 0.0074 16.3 0.2 3.9 4 2 1 5 5 5 1 Phospholipid methyltransferase DUF1295 PF06966.7 CCM01810.1 - 1.2 8.3 16.7 0.1 11.8 7.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1295) WD40 PF00400.27 CCM01811.1 - 4.9e-54 178.3 1.0 3e-10 39.5 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 CCM01811.1 - 2.2e-12 46.0 1.1 4.9e-12 44.8 0.8 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 CCM01811.1 - 0.0074 15.4 0.1 8.6 5.3 0.0 3.1 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PKD_channel PF08016.7 CCM01811.1 - 0.025 13.0 16.8 0.055 11.8 11.6 1.6 1 1 0 1 1 1 0 Polycystin cation channel Nup160 PF11715.3 CCM01811.1 - 0.13 10.3 2.5 3.5 5.6 0.0 3.4 3 2 0 4 4 4 0 Nucleoporin Nup120/160 PMT PF02366.13 CCM01812.1 - 9.4e-75 251.1 17.8 9.4e-75 251.1 12.3 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCM01812.1 - 2.2e-12 46.8 3.0 3.9e-12 46.1 2.1 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 CCM01812.1 - 4.2e-05 23.5 10.8 4.2e-05 23.5 7.5 2.6 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ank_2 PF12796.2 CCM01813.1 - 7.1e-12 45.5 1.9 1.8e-07 31.3 0.9 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCM01813.1 - 2.8e-10 39.4 6.4 1.2e-05 24.8 0.4 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCM01813.1 - 2.7e-09 36.3 3.8 8.3e-05 22.4 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CCM01813.1 - 6.8e-09 36.0 1.2 3.4e-06 27.4 0.3 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCM01813.1 - 4.4e-08 33.1 1.1 0.018 15.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 CCM01813.1 - 7.1e-05 22.3 0.1 0.0012 18.4 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Filament PF00038.16 CCM01813.1 - 0.052 13.0 0.7 0.086 12.2 0.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein Pox_A_type_inc PF04508.7 CCM01813.1 - 4.5 7.3 6.9 1.1 9.1 0.2 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PX PF00787.19 CCM01814.1 - 1.9e-15 56.6 0.0 7.8e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 PX domain TFIIS_M PF07500.9 CCM01815.1 - 3.5e-14 52.8 1.2 7.9e-14 51.7 0.8 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 CCM01815.1 - 3.9e-07 29.6 3.7 6.8e-07 28.8 2.6 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 CCM01815.1 - 5.3e-07 30.1 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 SPOC domain C1_1 PF00130.17 CCM01815.1 - 0.059 13.1 1.8 0.1 12.3 1.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 CCM01816.1 - 2.8e-69 233.1 0.0 4.2e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01816.1 - 7.5e-54 182.5 0.0 1.2e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CCM01816.1 - 1e-09 37.9 2.3 1.8e-09 37.1 1.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CH PF00307.26 CCM01816.1 - 3.1e-05 23.9 0.0 7.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 CCM01816.1 - 0.00091 19.2 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin Kinase-like PF14531.1 CCM01816.1 - 0.0053 15.7 0.0 0.14 11.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PHD PF00628.24 CCM01816.1 - 0.023 14.4 4.7 0.051 13.2 3.2 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 CCM01816.1 - 0.025 14.2 3.7 0.059 13.1 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 YrbL-PhoP_reg PF10707.4 CCM01816.1 - 0.026 13.8 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 CCM01816.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 CCM01816.1 - 0.14 10.9 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 C1_3 PF07649.7 CCM01816.1 - 3.7 7.6 2.7 7.5 6.6 1.8 1.5 1 0 0 1 1 1 0 C1-like domain Tnp_zf-ribbon_2 PF13842.1 CCM01816.1 - 4.5 7.7 6.8 8.8 6.8 4.7 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon HEAT_EZ PF13513.1 CCM01817.1 - 4.4e-17 62.0 15.0 9.7e-06 25.9 0.0 10.8 11 1 1 12 12 12 4 HEAT-like repeat HEAT PF02985.17 CCM01817.1 - 5.8e-17 60.2 13.0 0.018 15.0 0.1 9.6 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 CCM01817.1 - 4.5e-15 55.6 7.9 0.0012 19.0 0.0 7.2 5 2 3 8 8 8 6 HEAT repeats IBN_N PF03810.14 CCM01817.1 - 3.7e-10 39.5 0.1 6e-09 35.6 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 CCM01817.1 - 3.8e-06 27.2 0.0 0.97 9.8 0.0 5.7 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 CCM01817.1 - 0.00015 21.4 0.1 1.4 8.6 0.0 3.8 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 CCM01817.1 - 0.00017 20.9 0.2 0.19 11.0 0.0 4.3 4 2 1 5 5 5 1 CLASP N terminal Adaptin_N PF01602.15 CCM01817.1 - 0.0017 16.7 2.4 0.24 9.6 0.0 4.2 6 0 0 6 6 6 1 Adaptin N terminal region Xpo1 PF08389.7 CCM01817.1 - 0.0045 16.9 0.1 3.3 7.6 0.0 4.5 3 2 1 4 4 4 1 Exportin 1-like protein BP28CT PF08146.7 CCM01817.1 - 0.027 14.1 0.0 2.4 7.8 0.0 3.3 3 0 0 3 3 3 0 BP28CT (NUC211) domain Methyltransf_23 PF13489.1 CCM01818.1 - 7.9e-24 84.2 0.0 1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM01818.1 - 6.6e-18 64.9 0.0 1.4e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM01818.1 - 7.4e-15 55.4 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM01818.1 - 4.6e-14 52.6 0.0 1.1e-13 51.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM01818.1 - 2.9e-13 49.6 0.1 6.3e-12 45.3 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCM01818.1 - 2.5e-08 33.3 0.0 0.0012 17.9 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CCM01818.1 - 2.7e-07 30.6 0.0 6e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM01818.1 - 4.4e-07 30.1 0.0 1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCM01818.1 - 0.00017 20.8 0.0 0.00034 19.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CCM01818.1 - 0.004 16.5 0.4 0.062 12.6 0.2 2.3 1 1 1 2 2 2 1 Methyltransferase small domain MetW PF07021.7 CCM01818.1 - 0.0053 16.1 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CCM01818.1 - 0.047 13.3 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 CCM01818.1 - 0.06 12.0 0.0 5.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) AdoMet_MTase PF07757.8 CCM01818.1 - 0.064 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_15 PF09445.5 CCM01818.1 - 0.086 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CCDC144C PF14915.1 CCM01819.1 - 5.1e-05 22.3 0.5 6.3e-05 22.0 0.3 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region APG17 PF04108.7 CCM01819.1 - 0.0037 16.1 0.2 0.0053 15.6 0.1 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 Fib_alpha PF08702.5 CCM01819.1 - 0.037 14.1 0.6 0.053 13.6 0.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 CCM01819.1 - 0.047 13.7 2.7 0.064 13.2 1.9 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Med21 PF11221.3 CCM01819.1 - 0.059 13.3 0.7 4.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex BBP1_C PF15272.1 CCM01819.1 - 0.63 9.5 3.9 1.4 8.4 1.6 2.2 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Glyco_hydro_18 PF00704.23 CCM01821.1 - 8.4e-09 35.3 0.3 1.1e-08 34.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 CCM01822.1 - 3.9e-11 42.9 3.4 5.8e-11 42.4 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HELP PF03451.9 CCM01824.1 - 0.03 13.8 0.1 9.1 5.8 0.0 2.2 2 0 0 2 2 2 0 HELP motif COesterase PF00135.23 CCM01825.1 - 0.00048 18.9 0.1 0.00075 18.3 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 CCM01826.1 - 4.4e-73 246.8 0.1 5.6e-73 246.4 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM01826.1 - 1.9e-08 34.1 0.5 1.4e-07 31.3 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM01826.1 - 0.036 13.3 0.1 0.059 12.5 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box-like PF12937.2 CCM01828.1 - 4.6e-11 42.2 0.8 2e-10 40.2 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM01828.1 - 0.001 18.6 0.3 0.001 18.6 0.2 4.0 5 0 0 5 5 5 1 F-box domain Pyr_redox PF00070.22 CCM01829.1 - 9.3e-13 48.3 0.0 2.1e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCM01829.1 - 6.3e-10 39.2 0.2 0.046 13.5 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM01829.1 - 2.2e-05 23.5 0.9 0.047 12.5 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM01829.1 - 0.00037 19.5 0.0 0.51 9.1 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 CCM01829.1 - 0.0019 18.4 0.1 1 9.6 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding K_oxygenase PF13434.1 CCM01829.1 - 0.005 15.8 0.0 2.5 6.9 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CCM01829.1 - 0.0053 15.4 0.3 0.63 8.6 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 CCM01829.1 - 0.0076 16.2 0.1 3 7.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCM01829.1 - 0.0085 16.1 0.0 0.98 9.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CCM01829.1 - 0.014 15.4 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 CCM01829.1 - 0.06 13.1 0.6 2.6 7.8 0.0 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CCM01829.1 - 0.88 8.5 3.5 0.54 9.2 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain UQ_con PF00179.21 CCM01830.1 - 3.3e-16 58.9 0.0 3.6e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCM01830.1 - 0.0077 16.1 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CCM01830.1 - 0.045 13.4 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 UEV domain VHS PF00790.14 CCM01831.1 - 5.9e-33 113.4 0.1 9.9e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 CCM01831.1 - 1.7e-15 56.3 0.1 3.4e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCM01831.1 - 7.8e-14 50.8 0.1 1.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCM01831.1 - 1.1e-13 50.3 0.1 2.5e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 CCM01831.1 - 2.2e-06 27.5 0.5 6.7e-06 26.0 0.3 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.15 CCM01831.1 - 0.00016 20.9 1.0 0.00059 19.1 0.7 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Anoctamin PF04547.7 CCM01832.1 - 4.1e-88 295.9 0.2 6.7e-88 295.3 0.1 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Kinesin PF00225.18 CCM01834.1 - 2e-105 352.2 0.5 2e-105 352.2 0.4 1.5 2 0 0 2 2 2 1 Kinesin motor domain TMF_DNA_bd PF12329.3 CCM01834.1 - 0.0013 18.4 5.6 0.0013 18.4 3.9 4.3 3 1 1 4 4 4 1 TATA element modulatory factor 1 DNA binding DUF258 PF03193.11 CCM01834.1 - 0.022 13.9 0.0 0.086 12.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FliD_N PF02465.13 CCM01834.1 - 0.32 11.3 15.2 0.055 13.8 1.5 4.1 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Reo_sigmaC PF04582.7 CCM01834.1 - 0.69 9.0 13.5 0.3 10.2 1.3 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein ERM PF00769.14 CCM01834.1 - 1.9 7.9 37.4 4.6 6.7 25.9 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family RBD-FIP PF09457.5 CCM01834.1 - 3.5 7.5 19.5 3.9 7.3 3.6 3.5 3 0 0 3 3 3 0 FIP domain EMP24_GP25L PF01105.19 CCM01834.1 - 4.3 7.0 10.1 2.2 7.9 3.7 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD ATG16 PF08614.6 CCM01834.1 - 6.3 6.5 37.4 0.66 9.7 13.3 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-Q PF13094.1 CCM01834.1 - 9.4 6.2 37.6 35 4.3 4.3 3.7 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-GRF PF06839.7 CCM01835.1 - 2.4e-10 40.1 3.1 1.7e-07 31.0 0.2 2.5 2 0 0 2 2 2 2 GRF zinc finger Exo_endo_phos_2 PF14529.1 CCM01835.1 - 7.4e-10 38.4 0.0 2.9e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CCM01835.1 - 4.5e-06 26.7 0.2 8.8e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C2H2_jaz PF12171.3 CCM01836.1 - 1.5e-10 40.9 3.1 2.4e-10 40.2 2.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM01836.1 - 0.00055 20.0 1.3 0.0013 18.8 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCM01836.1 - 0.014 15.5 0.1 0.014 15.5 0.1 1.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DAP3 PF10236.4 CCM01839.1 - 4.1e-64 216.4 0.0 4.9e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CCM01839.1 - 0.00024 21.1 0.0 0.00054 19.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 CCM01839.1 - 0.0003 20.5 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 CCM01839.1 - 0.00071 19.7 0.0 0.0025 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCM01839.1 - 0.0033 16.8 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCM01839.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCM01839.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCM01839.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 CCM01839.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.10 CCM01839.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein F-box PF00646.28 CCM01840.1 - 0.00015 21.3 1.0 0.00015 21.3 0.7 4.0 4 1 0 4 4 4 1 F-box domain F-box-like PF12937.2 CCM01840.1 - 0.00037 20.1 0.4 0.00037 20.1 0.3 2.4 2 0 0 2 2 2 1 F-box-like DUF3760 PF12586.3 CCM01840.1 - 0.078 12.8 0.2 0.26 11.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Plus-3 PF03126.13 CCM01841.1 - 4.6e-23 81.3 0.3 3.2e-22 78.6 0.1 2.5 2 0 0 2 2 2 1 Plus-3 domain Aldo_ket_red PF00248.16 CCM01842.1 - 3.3e-64 216.4 0.0 3.7e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4198 PF10670.4 CCM01843.1 - 0.00071 19.6 0.7 0.0011 19.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) DUF4480 PF13715.1 CCM01843.1 - 0.0024 17.8 0.3 0.0041 17.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) CarboxypepD_reg PF13620.1 CCM01843.1 - 0.011 15.8 1.7 0.021 14.8 1.2 1.5 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Fe-S_biosyn PF01521.15 CCM01844.1 - 2.7e-20 72.3 0.0 3.6e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HIG_1_N PF04588.8 CCM01845.1 - 3.1e-19 68.4 2.3 6.7e-19 67.3 1.6 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4401 PF14351.1 CCM01845.1 - 0.089 11.7 0.7 0.13 11.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Urm1 PF09138.6 CCM01846.1 - 1.1e-32 112.0 0.0 1.8e-31 108.1 0.0 2.0 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CCM01846.1 - 2.1e-05 24.8 0.1 3.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 ThiS family BTB PF00651.26 CCM01848.1 - 1.7e-07 31.1 0.0 4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Cupin_2 PF07883.6 CCM01850.1 - 1.2e-05 24.6 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CCM01850.1 - 0.097 12.1 0.0 11 5.4 0.0 2.2 1 1 1 2 2 2 0 Cupin DUF16 PF01519.11 CCM01852.1 - 0.25 11.5 2.1 0.3 11.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF2889 PF11136.3 CCM01852.1 - 0.33 11.1 2.3 0.92 9.7 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2889) MFS_1 PF07690.11 CCM01857.1 - 1.1e-44 152.6 60.7 1.7e-42 145.4 41.0 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM01857.1 - 0.0013 17.4 40.8 0.0022 16.6 9.3 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter tRNA-synt_1b PF00579.20 CCM01858.1 - 8.5e-62 208.9 0.0 8.6e-61 205.6 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) DnaJ-X PF14308.1 CCM01858.1 - 2.9e-51 173.6 1.0 2.9e-51 173.6 0.7 2.0 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCM01858.1 - 1.1e-26 92.2 2.8 5.1e-26 90.1 1.9 2.3 1 0 0 1 1 1 1 DnaJ domain Tom5 PF10642.4 CCM01858.1 - 2.6 7.7 5.7 10 5.8 0.4 3.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase BTB PF00651.26 CCM01859.1 - 2.8e-13 49.7 0.2 9.7e-13 48.0 0.1 2.0 1 0 0 1 1 1 1 BTB/POZ domain HATPase_c_3 PF13589.1 CCM01859.1 - 4.1e-06 26.4 1.2 0.1 12.2 0.1 3.3 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FtsJ PF01728.14 CCM01860.1 - 3e-40 138.1 0.0 4.3e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PFL PF02901.10 CCM01860.1 - 0.23 9.8 0.0 0.32 9.3 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase Histone PF00125.19 CCM01861.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCM01861.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CCM01861.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CCM01861.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CCM01861.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CCM01861.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIIIC_sub6 PF10419.4 CCM01862.1 - 3.2e-08 32.8 0.1 5.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit ABC_tran PF00005.22 CCM01863.1 - 1.3e-47 161.4 0.0 4.8e-28 98.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCM01863.1 - 9.3e-42 143.3 34.2 2.6e-21 76.2 8.9 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 CCM01863.1 - 3.7e-11 43.5 0.9 0.025 14.5 0.1 4.5 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 CCM01863.1 - 4.3e-09 35.9 0.6 0.11 11.6 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCM01863.1 - 5.1e-08 33.4 1.7 0.00015 22.2 0.8 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CCM01863.1 - 2.6e-07 30.2 0.0 0.0093 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCM01863.1 - 9.8e-07 28.2 0.1 0.055 13.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CCM01863.1 - 1.3e-05 25.2 0.4 0.28 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 CCM01863.1 - 3e-05 24.4 0.0 0.15 12.5 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 CCM01863.1 - 3.2e-05 23.4 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 CCM01863.1 - 6.3e-05 22.0 0.0 0.024 13.5 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 CCM01863.1 - 9.3e-05 22.3 0.4 0.22 11.5 0.0 3.5 4 0 0 4 4 4 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CCM01863.1 - 0.00015 21.5 0.0 0.036 13.7 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 CCM01863.1 - 0.00016 21.4 0.2 0.67 9.6 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CCM01863.1 - 0.00024 21.8 0.0 1.5 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCM01863.1 - 0.00056 20.0 1.2 0.39 10.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 CCM01863.1 - 0.00065 19.5 0.5 0.11 12.3 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 CCM01863.1 - 0.00089 18.7 1.0 1.1 8.6 0.0 3.0 2 1 1 3 3 3 1 AAA-like domain DUF258 PF03193.11 CCM01863.1 - 0.0014 17.8 0.0 0.77 8.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Adeno_IVa2 PF02456.10 CCM01863.1 - 0.0016 17.1 0.0 0.0085 14.7 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_18 PF13238.1 CCM01863.1 - 0.0023 18.2 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCM01863.1 - 0.0032 16.8 0.1 1.6 8.1 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCM01863.1 - 0.0059 15.7 0.0 0.36 9.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 CCM01863.1 - 0.013 15.1 0.3 7.9 6.2 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 CCM01863.1 - 0.015 15.1 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 CCM01863.1 - 0.018 14.6 0.0 0.066 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 CCM01863.1 - 0.035 13.3 0.4 4.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.18 CCM01863.1 - 0.04 13.7 0.8 2.5 7.8 0.0 2.7 3 0 0 3 3 2 0 Dynamin family DEAD PF00270.24 CCM01863.1 - 0.057 12.9 0.0 14 5.1 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase SbcCD_C PF13558.1 CCM01863.1 - 0.061 13.2 0.4 6.8 6.6 0.1 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CCM01863.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CCM01863.1 - 0.14 11.8 0.9 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 CCM01863.1 - 0.15 11.5 1.7 0.77 9.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M3 PF01432.15 CCM01864.1 - 9.6e-66 222.6 0.0 1.9e-65 221.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 CCM01864.1 - 0.00032 20.1 0.5 0.00064 19.1 0.3 1.4 1 0 0 1 1 1 1 Peptidase M50B-like DUF2731 PF10806.3 CCM01864.1 - 0.069 13.3 0.1 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2731) HA2 PF04408.18 CCM01865.1 - 1.1e-21 76.7 1.2 2.4e-21 75.6 0.0 2.3 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCM01865.1 - 4.8e-19 68.2 0.0 1.2e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCM01865.1 - 3.1e-13 49.3 0.0 2.3e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCM01865.1 - 2.5e-10 40.5 3.2 2e-05 24.7 0.0 4.3 4 0 0 4 4 4 2 AAA domain DEAD PF00270.24 CCM01865.1 - 1.1e-06 28.2 0.0 5.3e-06 26.0 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 CCM01865.1 - 0.01 14.7 0.1 0.11 11.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein KaiC PF06745.8 CCM01865.1 - 0.011 14.8 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 CCM01865.1 - 0.017 15.0 0.1 0.8 9.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CCM01865.1 - 0.057 13.7 8.8 0.48 10.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 CCM01865.1 - 0.12 12.1 1.0 1.8 8.3 0.0 3.1 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 CCM01865.1 - 0.15 12.3 0.2 0.15 12.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain SEN1_N PF12726.2 CCM01866.1 - 5.8e-125 418.0 0.0 7.8e-125 417.6 0.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 CCM01866.1 - 8.3e-65 218.6 0.4 2.3e-64 217.1 0.3 1.8 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 CCM01866.1 - 3.3e-58 196.3 0.0 6.9e-58 195.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCM01866.1 - 1.8e-09 37.2 0.1 6e-09 35.5 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCM01866.1 - 3.5e-07 30.0 0.1 0.0005 19.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CCM01866.1 - 5.3e-05 22.9 0.3 0.59 9.7 0.0 3.6 3 0 0 3 3 3 2 NACHT domain Viral_helicase1 PF01443.13 CCM01866.1 - 0.00048 19.7 4.0 0.48 9.8 0.0 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CCM01866.1 - 0.0014 18.7 0.3 1.2 9.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CCM01866.1 - 0.0043 16.4 0.1 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CCM01866.1 - 0.041 14.2 0.0 0.041 14.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain Translin PF01997.11 CCM01867.1 - 1.2e-38 132.7 0.0 1.7e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Translin family DUF1325 PF07039.6 CCM01868.1 - 4.1e-31 107.2 0.0 6.9e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain RuvB_C PF05491.8 CCM01868.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB C-terminus HSP20 PF00011.16 CCM01869.1 - 4.8e-15 55.2 0.1 1.2e-07 31.5 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family CBFD_NFYB_HMF PF00808.18 CCM01870.1 - 4.1e-07 29.9 0.0 7.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAGA-Tad1 PF12767.2 CCM01870.1 - 0.072 12.7 3.6 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit tRNA_bind PF01588.15 CCM01871.1 - 1.4e-29 101.7 0.1 8.9e-29 99.1 0.0 2.1 2 0 0 2 2 2 1 Putative tRNA binding domain GST_C PF00043.20 CCM01871.1 - 1.2e-06 28.3 0.2 3.3e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCM01871.1 - 8.7e-06 26.1 0.0 2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCM01871.1 - 0.043 13.7 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Menin PF05053.8 CCM01871.1 - 0.12 10.5 0.5 0.13 10.4 0.4 1.2 1 0 0 1 1 1 0 Menin Ribosomal_L6 PF00347.18 CCM01872.1 - 1e-22 80.3 0.0 2.8e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 Abhydrolase_5 PF12695.2 CCM01873.1 - 1.9e-06 27.7 0.3 2.7e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM01873.1 - 0.00015 21.6 2.0 0.035 13.9 0.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.6 CCM01873.1 - 0.066 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 CCM01873.1 - 0.087 12.0 0.0 0.13 11.4 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.3 CCM01873.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) vATP-synt_AC39 PF01992.11 CCM01874.1 - 2e-97 326.3 0.0 3.4e-97 325.5 0.0 1.4 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit CRAL_TRIO PF00650.15 CCM01875.1 - 1.3e-27 96.2 0.0 2e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCM01875.1 - 6.2e-13 48.6 0.2 3.7e-12 46.1 0.2 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Gas_vesicle_C PF01304.12 CCM01876.1 - 0.55 9.9 5.7 0.49 10.0 0.3 2.5 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain zf-CCHC_3 PF13917.1 CCM01877.1 - 3.6e-20 71.4 1.4 6.2e-20 70.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Cwf_Cwc_15 PF04889.7 CCM01877.1 - 0.0046 16.7 12.2 0.0051 16.5 8.5 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.5 CCM01877.1 - 0.028 13.5 11.2 0.03 13.3 7.8 1.1 1 0 0 1 1 1 0 BUD22 Plasmodium_Vir PF05795.6 CCM01877.1 - 0.056 12.6 6.4 0.068 12.3 4.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-C4pol PF14260.1 CCM01877.1 - 0.088 12.8 0.4 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-CCHC PF00098.18 CCM01877.1 - 0.1 12.5 0.8 0.16 11.9 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle TFIIF_alpha PF05793.7 CCM01877.1 - 0.17 10.2 15.9 0.19 10.0 11.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.7 CCM01877.1 - 0.24 10.5 4.7 0.3 10.3 3.3 1.2 1 0 0 1 1 1 0 NOA36 protein FAM60A PF15396.1 CCM01877.1 - 0.3 10.7 6.8 0.38 10.4 4.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.5 CCM01877.1 - 0.36 10.8 7.7 0.52 10.3 5.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nucleo_P87 PF07267.6 CCM01877.1 - 0.43 9.1 7.0 0.44 9.1 4.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1510 PF07423.6 CCM01877.1 - 0.54 9.5 10.4 0.67 9.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 CCM01877.1 - 0.61 8.0 13.6 0.71 7.8 9.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 CCM01877.1 - 1 7.5 8.4 1.1 7.4 5.8 1.2 1 0 0 1 1 1 0 Transmembrane protein FLO_LFY PF01698.11 CCM01877.1 - 1.1 8.0 7.1 1.2 7.8 4.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Orthopox_A36R PF05950.6 CCM01877.1 - 2.6 7.9 8.8 3.7 7.4 6.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus A36R protein BTV_NS2 PF04514.7 CCM01877.1 - 3.2 6.5 7.7 3.7 6.3 5.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FancD2 PF14631.1 CCM01877.1 - 3.6 4.5 7.3 3.9 4.4 5.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Nop14 PF04147.7 CCM01877.1 - 3.8 5.2 14.7 4.6 5.0 10.2 1.0 1 0 0 1 1 1 0 Nop14-like family RAP1 PF07218.6 CCM01877.1 - 5.5 4.9 9.7 6.4 4.7 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CobT PF06213.7 CCM01877.1 - 5.8 5.9 15.3 8.7 5.3 10.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MFMR PF07777.6 CCM01877.1 - 6.2 6.7 13.5 8.8 6.2 9.3 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR Tom22 PF04281.8 CCM01877.1 - 6.5 6.2 10.4 10 5.6 7.2 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Hid1 PF12722.2 CCM01877.1 - 6.8 4.2 7.5 7.3 4.1 5.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATP-synt_C PF00137.16 CCM01878.1 - 5.9e-26 90.1 31.6 4.8e-16 58.4 5.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_J PF04911.7 CCM01878.1 - 4.1 6.9 4.8 17 4.9 0.2 2.5 2 0 0 2 2 2 0 ATP synthase j chain Pkinase PF00069.20 CCM01879.1 - 4.7e-50 170.1 0.0 7.1e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HpcH_HpaI PF03328.9 CCM01879.1 - 1.7e-40 138.2 0.0 3.5e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Pkinase_Tyr PF07714.12 CCM01879.1 - 8.4e-23 80.7 0.0 8.4e-22 77.4 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase C-C_Bond_Lyase PF15617.1 CCM01879.1 - 1.6e-10 40.3 0.2 3.7e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Kinase-like PF14531.1 CCM01879.1 - 5.4e-05 22.2 0.0 0.00079 18.4 0.0 2.4 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.17 CCM01879.1 - 0.026 13.8 0.7 0.081 12.2 0.2 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 CCM01879.1 - 0.15 11.0 0.2 0.38 9.7 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.2 CCM01880.1 - 6.1e-26 91.7 0.0 8.1e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM01880.1 - 8.1e-16 58.2 0.0 1.3e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM01880.1 - 2.6e-09 36.9 0.0 1.3e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CCM01880.1 - 7.8e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 CCM01880.1 - 0.0023 18.2 0.0 0.0033 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain BAAT_C PF08840.6 CCM01880.1 - 0.016 14.9 0.0 0.17 11.5 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 CCM01880.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase FSH1 PF03959.8 CCM01880.1 - 0.076 12.4 0.1 8 5.8 0.0 2.5 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DUF915 PF06028.6 CCM01880.1 - 0.2 10.7 0.2 0.51 9.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) OB_NTP_bind PF07717.11 CCM01881.1 - 6.3e-28 96.8 0.1 1.5e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCM01881.1 - 2.6e-25 88.3 0.0 2.6e-25 88.3 0.0 3.3 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCM01881.1 - 6.9e-14 51.4 0.0 2.1e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCM01881.1 - 4.7e-07 29.4 0.1 1.9e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCM01881.1 - 0.00034 20.7 0.1 0.0017 18.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CCM01881.1 - 0.0055 15.6 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 CCM01881.1 - 0.19 11.5 0.9 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 CCM01881.1 - 3.7 7.3 7.8 2.2 8.0 0.0 3.2 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit AhpC-TSA PF00578.16 CCM01882.1 - 1.1e-17 63.8 0.0 5.6e-17 61.5 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCM01882.1 - 3.2e-10 39.7 0.0 4.4e-10 39.2 0.0 1.2 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CCM01882.1 - 0.04 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DAHP_synth_1 PF00793.15 CCM01883.1 - 5.9e-90 300.6 0.0 7.5e-90 300.3 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family DUF4231 PF14015.1 CCM01885.1 - 0.77 9.7 5.8 2.4 8.1 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) AMP-binding PF00501.23 CCM01886.1 - 4e-63 213.2 0.0 5e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCM01886.1 - 2.3e-07 31.6 0.0 1e-06 29.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4243 PF14027.1 CCM01887.1 - 7.7e-81 272.0 0.0 9.1e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Epimerase PF01370.16 CCM01888.1 - 4.8e-23 81.8 0.0 6.8e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM01888.1 - 4.4e-15 55.1 0.0 7.8e-15 54.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCM01888.1 - 9.8e-14 51.7 0.2 3.3e-13 50.0 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCM01888.1 - 7.2e-11 41.4 0.2 2.4e-10 39.7 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CCM01888.1 - 8.5e-05 21.9 0.3 0.00012 21.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CCM01888.1 - 0.00085 19.2 1.4 0.0035 17.2 0.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM01888.1 - 0.032 13.8 1.0 0.085 12.5 0.7 1.7 1 1 0 1 1 1 0 KR domain Methyltransf_26 PF13659.1 CCM01888.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain GTP_EFTU PF00009.22 CCM01889.1 - 4e-54 182.9 0.0 6.9e-54 182.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CCM01889.1 - 3.3e-16 58.9 0.0 8e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 CCM01889.1 - 2.3e-06 27.5 0.1 5.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CCM01889.1 - 2.5e-05 24.2 0.0 6.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 CCM01889.1 - 0.041 13.0 0.1 0.21 10.7 0.1 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 CCM01889.1 - 0.099 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin Miro PF08477.8 CCM01889.1 - 0.11 13.0 0.1 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein RasGEF PF00617.14 CCM01890.1 - 1.6e-52 177.9 0.2 2.6e-52 177.2 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCM01890.1 - 2.9e-18 65.8 0.0 9.2e-18 64.2 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 CCM01891.1 - 4.6e-16 57.9 0.3 1.8e-15 56.0 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CCM01891.1 - 7e-14 51.1 1.6 2.5e-13 49.3 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CCM01891.1 - 7.8e-11 41.3 0.0 1.9e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 CCM01891.1 - 3.1e-10 39.7 0.3 0.00042 20.1 0.1 2.5 2 0 0 2 2 2 2 WW domain DASH_Dad1 PF08649.5 CCM01892.1 - 3.2e-16 58.7 0.1 4.5e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.5 CCM01892.1 - 0.043 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pkinase PF00069.20 CCM01893.1 - 2.8e-58 197.1 0.0 6.4e-58 195.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM01893.1 - 8.6e-29 100.3 0.0 1.2e-27 96.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 CCM01893.1 - 5.9e-23 80.3 11.7 9.9e-14 50.8 4.9 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 CCM01893.1 - 5.6e-20 70.8 27.3 3.6e-11 42.6 7.0 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CCM01893.1 - 2.4e-10 40.7 0.4 1.2e-09 38.5 0.4 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCM01893.1 - 0.054 12.4 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Endosulfine PF04667.12 CCM01894.1 - 8.7e-18 64.0 0.0 1.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region CwfJ_C_1 PF04677.10 CCM01895.1 - 3.6e-31 107.3 0.0 5.7e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DNA_pol_E_B PF04042.11 CCM01895.1 - 5.4e-30 104.2 0.3 8.9e-30 103.4 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CwfJ_C_2 PF04676.9 CCM01895.1 - 2.8e-24 85.4 0.1 2.9e-23 82.1 0.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Pol_alpha_B_N PF08418.5 CCM01895.1 - 1.2e-17 64.3 6.2 4.7e-09 36.1 0.1 3.4 4 0 0 4 4 4 2 DNA polymerase alpha subunit B N-terminal cobW PF02492.14 CCM01896.1 - 1.4e-43 148.4 0.4 2e-43 147.8 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CCM01896.1 - 1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 CCM01896.1 - 1.8e-06 27.5 0.1 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CCM01896.1 - 0.00058 20.0 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCM01896.1 - 0.0021 17.9 0.3 0.006 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CCM01896.1 - 0.006 16.5 0.1 0.022 14.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CCM01896.1 - 0.0067 16.1 0.0 0.0099 15.6 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 CCM01896.1 - 0.007 16.6 1.1 0.02 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CCM01896.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 CCM01896.1 - 0.012 14.4 1.7 0.2 10.4 0.0 3.0 4 0 0 4 4 4 0 ArgK protein MobB PF03205.9 CCM01896.1 - 0.016 14.8 0.3 0.074 12.7 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CCM01896.1 - 0.029 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CCM01896.1 - 0.062 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 CCM01896.1 - 0.081 12.1 0.4 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Viral_helicase1 PF01443.13 CCM01896.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 CCM01896.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CCM01896.1 - 0.25 12.1 3.1 0.36 11.6 0.1 2.7 2 2 1 3 3 3 0 AAA domain DSPc PF00782.15 CCM01897.1 - 7.8e-29 99.9 0.0 1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCM01897.1 - 0.0007 19.8 0.1 0.087 13.0 0.0 2.3 1 1 1 2 2 2 2 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 CCM01897.1 - 0.0014 17.5 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 CCM01897.1 - 0.026 13.8 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UAA PF08449.6 CCM01898.1 - 2.1e-62 210.7 5.5 3.1e-62 210.2 3.8 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CCM01898.1 - 7e-11 42.2 16.9 2e-08 34.3 4.1 3.4 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CCM01898.1 - 4.6e-06 26.8 17.5 9.2e-05 22.6 3.3 3.4 3 1 0 4 4 4 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CCM01898.1 - 0.00094 18.3 4.9 0.057 12.5 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 CCM01898.1 - 0.0014 18.3 5.2 0.0014 18.3 3.6 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family DUF914 PF06027.7 CCM01898.1 - 0.019 13.8 5.0 0.12 11.2 3.5 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) Vma12 PF11712.3 CCM01898.1 - 0.18 11.4 0.6 0.49 10.0 0.0 2.0 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase UPF0546 PF10639.4 CCM01898.1 - 3.2 7.6 9.7 3.3 7.5 0.5 3.4 3 1 1 4 4 4 0 Uncharacterised protein family UPF0546 Yae1_N PF09811.4 CCM01899.1 - 3.8e-12 45.5 1.1 3.8e-12 45.5 0.7 1.6 2 0 0 2 2 2 1 Essential protein Yae1, N terminal FAD_binding_1 PF00667.15 CCM01900.1 - 4.4e-54 183.2 0.0 3.4e-53 180.3 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCM01900.1 - 1.1e-28 100.0 0.2 2.2e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCM01900.1 - 4.4e-22 78.7 0.0 1.9e-21 76.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 CCM01900.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin domain She9_MDM33 PF05546.6 CCM01901.1 - 2.8e-71 239.3 10.8 3.7e-71 238.9 7.5 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Peptidase_S46 PF10459.4 CCM01901.1 - 0.0018 16.7 6.5 0.0022 16.5 4.5 1.2 1 0 0 1 1 1 1 Peptidase S46 CBFD_NFYB_HMF PF00808.18 CCM01902.1 - 6.1e-12 45.4 1.0 9.2e-12 44.8 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCM01902.1 - 0.00012 22.1 1.2 0.00017 21.6 0.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CPSF_A PF03178.10 CCM01903.1 - 5.9e-51 173.4 0.0 8e-49 166.4 0.0 3.7 3 1 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 CCM01903.1 - 5.2e-42 143.6 0.0 1.5e-41 142.1 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Na_Ca_ex PF01699.19 CCM01904.1 - 1e-22 80.2 27.8 3.3e-14 52.6 5.8 3.4 4 1 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CCM01904.1 - 5.1e-12 46.0 14.8 5.1e-12 46.0 10.3 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF307) Borrelia_P13 PF05628.7 CCM01904.1 - 0.23 11.2 3.4 0.29 10.9 1.6 1.8 1 1 0 1 1 1 0 Borrelia membrane protein P13 DMAP_binding PF06464.6 CCM01905.1 - 0.013 16.1 0.6 0.056 14.0 0.0 2.5 2 0 0 2 2 2 0 DMAP1-binding Domain ERG4_ERG24 PF01222.12 CCM01906.1 - 1e-134 449.3 10.6 1.3e-134 449.0 7.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CCM01906.1 - 4.6e-06 26.1 0.3 4.6e-06 26.1 0.2 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CCM01906.1 - 8.8e-05 22.5 0.1 8.8e-05 22.5 0.1 3.2 4 1 1 5 5 5 1 Phospholipid methyltransferase ICMT PF04140.9 CCM01906.1 - 0.00083 19.5 0.3 0.012 15.8 0.0 2.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family GPI-anchored PF10342.4 CCM01907.1 - 7e-07 29.6 0.5 1e-06 29.1 0.4 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CCM01907.1 - 0.013 15.0 0.1 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SUR7 PF06687.7 CCM01908.1 - 5.7e-09 35.8 22.0 6e-05 22.7 1.0 2.2 1 1 1 2 2 2 2 SUR7/PalI family Claudin_3 PF06653.6 CCM01908.1 - 0.025 14.2 12.4 0.072 12.8 8.6 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Cation_efflux PF01545.16 CCM01908.1 - 1.3 8.0 12.8 0.23 10.5 6.0 1.7 1 1 1 2 2 2 0 Cation efflux family Whi5 PF08528.6 CCM01909.1 - 0.0036 16.8 0.3 0.0067 16.0 0.2 1.4 1 0 0 1 1 1 1 Whi5 like DUF2415 PF10313.4 CCM01911.1 - 1.8e-08 33.9 0.1 6.6e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 CCM01911.1 - 0.26 11.2 7.8 3.9 7.5 0.1 5.3 6 1 0 6 6 6 0 WD domain, G-beta repeat zf-C2H2 PF00096.21 CCM01912.1 - 8.4e-11 41.5 15.0 0.00074 19.7 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM01912.1 - 7.2e-10 38.4 11.2 0.0056 16.9 0.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCM01912.1 - 2e-08 34.0 12.8 0.00082 19.5 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 CCM01912.1 - 0.091 13.0 5.6 0.48 10.7 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCM01912.1 - 7.1 6.9 6.9 9.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding MMR_HSR1 PF01926.18 CCM01913.1 - 3.5e-11 43.0 0.5 7.5e-10 38.7 0.1 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 CCM01913.1 - 3e-08 33.0 1.1 1.4e-06 27.5 0.0 2.3 1 1 1 2 2 2 1 AIG1 family Dynamin_N PF00350.18 CCM01913.1 - 6e-06 26.1 8.9 0.013 15.3 0.1 3.2 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CCM01913.1 - 3.2e-05 23.1 0.3 9.9e-05 21.5 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CCM01913.1 - 0.00028 20.2 0.2 0.00078 18.7 0.0 1.9 2 0 0 2 2 1 1 Ferrous iron transport protein B TPR_14 PF13428.1 CCM01913.1 - 0.0055 17.2 2.3 0.75 10.5 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Miro PF08477.8 CCM01913.1 - 0.0065 16.9 0.1 0.091 13.2 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein Septin PF00735.13 CCM01913.1 - 0.007 15.4 1.1 0.01 14.8 0.0 1.8 2 1 0 2 2 2 1 Septin AAA_23 PF13476.1 CCM01913.1 - 0.0095 16.2 10.4 0.062 13.6 7.2 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCM01913.1 - 0.016 15.4 1.9 0.041 14.1 0.1 2.2 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 CCM01913.1 - 0.026 13.9 0.7 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain IIGP PF05049.8 CCM01913.1 - 0.026 13.3 0.1 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Mnd1 PF03962.10 CCM01913.1 - 0.028 14.0 8.0 0.047 13.3 5.6 1.3 1 0 0 1 1 1 0 Mnd1 family Peptidase_M29 PF02073.10 CCM01913.1 - 0.035 12.8 0.5 0.055 12.2 0.4 1.3 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Gtr1_RagA PF04670.7 CCM01913.1 - 0.047 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF342 PF03961.8 CCM01913.1 - 0.065 11.6 2.0 0.086 11.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_22 PF13401.1 CCM01913.1 - 0.074 13.1 0.8 0.95 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain GBP PF02263.14 CCM01913.1 - 0.096 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_17 PF13207.1 CCM01913.1 - 0.11 13.3 2.1 0.26 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF1993 PF09351.5 CCM01913.1 - 0.25 11.2 1.4 0.74 9.7 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) DUF883 PF05957.8 CCM01913.1 - 0.4 11.0 6.2 1.1 9.7 4.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF87 PF01935.12 CCM01913.1 - 0.68 9.7 6.8 3.7 7.2 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Fzo_mitofusin PF04799.8 CCM01913.1 - 0.74 9.1 4.1 1.3 8.3 2.9 1.4 1 0 0 1 1 1 0 fzo-like conserved region FUSC PF04632.7 CCM01913.1 - 0.87 7.9 2.9 1.2 7.4 2.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ArgK PF03308.11 CCM01913.1 - 0.92 8.2 5.4 0.2 10.3 0.3 2.2 3 0 0 3 3 3 0 ArgK protein OmpH PF03938.9 CCM01913.1 - 1.1 9.2 9.0 1.9 8.4 6.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_16 PF13191.1 CCM01913.1 - 1.1 9.2 5.1 5.8 6.8 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF724 PF05266.9 CCM01913.1 - 1.6 8.3 9.3 2.6 7.6 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MDMPI_N PF11716.3 CCM01913.1 - 2.4 8.5 4.6 4 7.8 3.2 1.5 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF4463 PF14703.1 CCM01913.1 - 4.6 7.8 8.2 93 3.6 5.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) MMR_HSR1 PF01926.18 CCM01914.1 - 1.6e-11 44.1 0.0 3.5e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CCM01914.1 - 2.3e-08 33.4 0.2 3.8e-08 32.7 0.1 1.5 1 1 0 1 1 1 1 AIG1 family Septin PF00735.13 CCM01914.1 - 4e-07 29.3 0.0 8.9e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_17 PF13207.1 CCM01914.1 - 5e-06 27.3 0.1 1.6e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 CCM01914.1 - 8.5e-06 25.6 1.7 0.092 12.5 0.0 2.8 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CCM01914.1 - 1.2e-05 24.5 0.0 2.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CCM01914.1 - 1.3e-05 24.5 0.0 2.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CCM01914.1 - 4.2e-05 23.6 0.5 0.00019 21.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 CCM01914.1 - 5.4e-05 23.6 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 CCM01914.1 - 0.00029 20.5 0.2 0.00077 19.1 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCM01914.1 - 0.00061 19.8 0.4 0.0055 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CCM01914.1 - 0.00066 20.0 5.9 0.0044 17.3 3.9 2.3 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CCM01914.1 - 0.00082 18.3 0.1 0.0018 17.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.10 CCM01914.1 - 0.002 17.8 0.1 0.0069 16.1 0.1 1.9 2 0 0 2 2 1 1 NTPase AAA PF00004.24 CCM01914.1 - 0.0025 18.0 0.0 0.0055 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CCM01914.1 - 0.0025 17.3 0.5 0.012 15.0 0.4 2.3 1 1 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 CCM01914.1 - 0.0031 17.8 0.9 0.0065 16.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 CCM01914.1 - 0.0034 16.9 0.7 0.29 10.6 0.2 2.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 CCM01914.1 - 0.0041 17.0 0.2 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCM01914.1 - 0.0047 16.4 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRPRB PF09439.5 CCM01914.1 - 0.0048 16.1 0.4 0.009 15.2 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 CCM01914.1 - 0.012 15.9 0.4 0.045 14.0 0.0 2.1 2 1 0 2 2 2 0 ABC transporter IIGP PF05049.8 CCM01914.1 - 0.018 13.8 0.1 0.035 12.9 0.1 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NB-ARC PF00931.17 CCM01914.1 - 0.02 13.7 0.5 0.069 12.0 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.1 CCM01914.1 - 0.021 14.7 0.2 0.069 13.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CCM01914.1 - 0.021 14.5 0.2 0.048 13.4 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 CCM01914.1 - 0.044 13.7 2.3 0.2 11.6 0.1 2.8 3 1 0 3 3 3 0 AAA domain cobW PF02492.14 CCM01914.1 - 0.094 12.1 0.1 0.26 10.7 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 CCM01914.1 - 0.098 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 CCM01914.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CCM01914.1 - 0.15 11.6 0.7 0.37 10.4 0.0 2.0 2 1 0 2 2 2 0 NACHT domain APG6 PF04111.7 CCM01914.1 - 0.21 10.6 4.0 0.5 9.3 2.3 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 CCM01914.1 - 0.26 10.8 7.0 0.39 10.2 4.8 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 CCM01914.1 - 0.64 10.3 6.3 0.44 10.8 2.5 2.1 2 1 1 3 3 2 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 CCM01914.1 - 1 7.7 4.8 1.5 7.1 3.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-F_leu_zip PF10473.4 CCM01914.1 - 2.3 8.0 14.9 10 5.9 9.5 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RAI1 PF08652.6 CCM01915.1 - 1e-20 73.2 0.0 1.9e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease TPR_11 PF13414.1 CCM01916.1 - 3e-18 65.2 5.2 1.9e-10 40.2 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CCM01916.1 - 3.1e-13 48.6 0.7 1.4e-05 24.4 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCM01916.1 - 1.6e-11 43.2 5.8 0.00023 20.8 0.1 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM01916.1 - 1.1e-10 41.8 7.8 1.6e-08 34.9 0.1 4.6 4 2 1 5 5 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCM01916.1 - 1.6e-07 30.9 1.3 0.0084 16.2 0.0 3.5 5 0 0 5 5 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCM01916.1 - 6.4e-07 28.7 0.4 0.26 11.2 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM01916.1 - 8.2e-07 28.8 8.8 0.003 17.4 0.0 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM01916.1 - 1.4e-06 28.3 13.0 0.013 16.0 0.1 5.6 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCM01916.1 - 3.8e-06 27.1 7.8 0.00097 19.4 0.5 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCM01916.1 - 0.00057 19.4 1.0 0.36 10.7 0.0 3.7 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCM01916.1 - 0.00061 18.9 2.6 0.18 10.7 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CCM01916.1 - 0.0031 17.6 0.1 0.0079 16.3 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 CCM01916.1 - 0.018 15.1 1.0 0.47 10.5 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCM01916.1 - 0.028 14.3 7.3 1.1 9.3 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCM01916.1 - 0.03 14.1 1.7 0.8 9.6 0.3 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat ILVD_EDD PF00920.16 CCM01917.1 - 1.4e-190 634.1 0.0 1.6e-190 633.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family AIM24 PF01987.12 CCM01919.1 - 1.9e-47 161.5 0.1 2.2e-47 161.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ank PF00023.25 CCM01921.1 - 1.3e-11 43.6 0.8 0.00017 21.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CCM01921.1 - 5.9e-11 42.5 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCM01921.1 - 2.9e-08 33.6 0.4 0.00013 22.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM01921.1 - 4.2e-08 32.6 0.2 0.0039 17.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CCM01921.1 - 7e-07 29.5 0.1 0.00013 22.4 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TIG PF01833.19 CCM01921.1 - 0.0034 17.3 0.0 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 IPT/TIG domain Propep_M14 PF02244.11 CCM01921.1 - 0.11 12.2 0.2 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 Carboxypeptidase activation peptide zf-TRM13_CCCH PF11722.3 CCM01921.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein GST_N_3 PF13417.1 CCM01922.1 - 6.9e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCM01922.1 - 7.9e-13 48.2 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCM01922.1 - 1.2e-11 44.5 0.0 3.8e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM01922.1 - 2.5e-10 40.2 0.0 6.5e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM01922.1 - 1.9e-05 24.4 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCM01922.1 - 0.0099 16.3 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCM01923.1 - 1.7e-14 53.7 0.0 2.8e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCM01923.1 - 1.6e-13 50.5 0.0 2.7e-12 46.6 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM01923.1 - 4.5e-12 45.7 0.0 1.2e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCM01923.1 - 9.8e-09 35.0 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCM01923.1 - 0.00038 20.2 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCM01923.1 - 0.0027 18.1 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UPF0029 PF01205.14 CCM01924.1 - 1.2e-20 73.1 0.0 2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 SPDY PF03771.11 CCM01924.1 - 0.013 14.9 0.1 0.029 13.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF317) ATP_transf PF09830.4 CCM01925.1 - 6.8e-18 64.2 0.0 1.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase Med3 PF11593.3 CCM01928.1 - 0.55 9.4 17.7 1 8.5 12.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 CCM01928.1 - 8.3 6.1 28.3 0.59 9.9 5.4 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 CCM01928.1 - 9.7 5.6 16.5 12 5.3 0.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin YcfA PF07927.7 CCM01929.1 - 0.00071 19.4 0.0 0.00088 19.1 0.0 1.2 1 0 0 1 1 1 1 YcfA-like protein RabGAP-TBC PF00566.13 CCM01930.1 - 3.9e-51 173.5 0.0 5.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ran_BP1 PF00638.13 CCM01931.1 - 8.7e-12 45.1 0.2 1.7e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 CCM01931.1 - 4.5e-11 42.9 1.0 4.5e-11 42.9 0.7 6.1 5 2 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) Ferritin_2 PF13668.1 CCM01932.1 - 1.3e-18 67.2 0.8 2e-18 66.6 0.5 1.2 1 0 0 1 1 1 1 Ferritin-like domain NRDE-2 PF08424.5 CCM01932.1 - 0.053 12.4 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Pectate_lyase_3 PF12708.2 CCM01933.1 - 9.2e-68 228.7 19.0 1.9e-56 191.7 7.0 3.9 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 CCM01933.1 - 4.8e-05 22.7 2.8 0.037 13.4 0.3 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase AA_permease PF00324.16 CCM01935.1 - 8.5e-120 400.2 37.8 1.2e-119 399.8 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCM01935.1 - 1.1e-33 116.4 42.5 1.6e-33 115.9 29.4 1.2 1 0 0 1 1 1 1 Amino acid permease LRR_4 PF12799.2 CCM01935.1 - 1.7e-07 30.7 7.2 7.4e-06 25.4 1.4 2.8 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM01935.1 - 1.1e-05 25.0 4.2 0.0002 21.0 0.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CCM01935.1 - 0.041 13.8 7.3 3.3 8.1 0.2 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 CCM01935.1 - 0.19 12.0 4.1 15 6.3 0.1 4.3 4 0 0 4 4 4 0 Leucine rich repeat RhoGEF PF00621.15 CCM01936.1 - 5.4e-45 153.4 0.0 8.3e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Mito_carr PF00153.22 CCM01937.1 - 3.5e-60 199.7 0.2 2.2e-19 68.9 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 CCM01938.1 - 6.7e-18 64.5 0.0 1.1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 CCM01938.1 - 3.4e-10 39.4 3.8 8.4e-10 38.1 2.6 1.7 1 0 0 1 1 1 1 SNARE domain CBS PF00571.23 CCM01939.1 - 5e-31 106.2 1.3 2.5e-12 46.3 0.0 4.4 4 0 0 4 4 4 4 CBS domain SPRY PF00622.23 CCM01940.1 - 4.6e-18 65.4 0.1 7.3e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain EphA2_TM PF14575.1 CCM01941.1 - 0.0074 16.6 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD20 PF04103.10 CCM01941.1 - 0.0085 16.0 0.0 0.0098 15.8 0.0 1.1 1 0 0 1 1 1 1 CD20-like family DUF1180 PF06679.7 CCM01941.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Herpes_gE PF02480.11 CCM01941.1 - 0.013 13.7 0.0 0.015 13.6 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SieB PF14163.1 CCM01941.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B Shisa PF13908.1 CCM01941.1 - 0.042 14.0 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 CCM01941.1 - 0.054 13.0 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 IncA protein DUF3357 PF11837.3 CCM01941.1 - 0.063 13.1 0.0 0.082 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) TMEM154 PF15102.1 CCM01941.1 - 0.074 12.7 0.0 0.077 12.7 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family OATP PF03137.15 CCM01941.1 - 0.12 10.4 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family YebO PF13974.1 CCM01941.1 - 3 7.6 4.9 2.5 7.9 2.4 1.6 1 1 1 2 2 2 0 YebO-like protein tRNA-synt_2 PF00152.15 CCM01942.1 - 1e-82 277.6 0.3 1.5e-82 277.0 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCM01942.1 - 4.9e-09 35.9 0.0 8.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCM01942.1 - 0.0054 15.9 2.4 0.81 8.8 0.0 3.3 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) Erythro_esteras PF05139.9 CCM01942.1 - 0.028 13.6 2.3 2.2 7.3 0.0 3.2 4 0 0 4 4 4 0 Erythromycin esterase Aminotran_1_2 PF00155.16 CCM01943.1 - 3.7e-89 299.2 0.0 4.2e-89 299.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Elong_Iki1 PF10483.4 CCM01945.1 - 2.1e-06 27.3 0.1 7.6e-05 22.2 0.1 2.7 1 1 0 1 1 1 1 Elongator subunit Iki1 Abhydrolase_6 PF12697.2 CCM01946.1 - 2.7e-19 69.9 0.1 3.3e-19 69.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM01946.1 - 5.9e-11 42.3 0.0 7.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM01946.1 - 1.2e-10 41.2 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCM01946.1 - 1.9e-05 24.4 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 CCM01946.1 - 0.00032 20.0 0.1 0.0019 17.5 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.20 CCM01946.1 - 0.022 14.3 0.2 0.03 13.9 0.1 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 CCM01946.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Acetyltransf_8 PF13523.1 CCM01947.1 - 0.00028 20.8 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCM01947.1 - 0.0072 16.4 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DLH PF01738.13 CCM01948.1 - 7.5e-20 71.1 0.0 9.5e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCM01948.1 - 0.00029 20.5 0.0 0.0004 20.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 CCM01948.1 - 0.004 16.5 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) GTP_EFTU PF00009.22 CCM01949.1 - 2.1e-56 190.3 0.1 3.2e-56 189.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Pkinase PF00069.20 CCM01949.1 - 2.2e-39 135.1 0.0 1.3e-37 129.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain GTP_EFTU_D3 PF03143.12 CCM01949.1 - 9.9e-36 121.8 0.0 2.3e-35 120.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCM01949.1 - 3.9e-17 62.1 2.0 1.1e-16 60.6 1.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Pkinase_Tyr PF07714.12 CCM01949.1 - 5.9e-15 55.0 0.0 1.1e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM01949.1 - 3.1e-05 23.0 0.0 5.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like GTP_EFTU_D4 PF14578.1 CCM01949.1 - 0.00025 20.6 0.7 0.00059 19.4 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCM01949.1 - 0.0081 16.1 0.1 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Kdo PF06293.9 CCM01949.1 - 0.03 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM01949.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L32e PF01655.13 CCM01950.1 - 1.5e-48 163.3 2.3 1.8e-48 163.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Memo PF01875.12 CCM01951.1 - 6.1e-73 245.0 0.0 7e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein HABP4_PAI-RBP1 PF04774.10 CCM01952.1 - 6.1e-05 23.4 12.1 6.1e-05 23.4 8.4 3.9 3 2 1 4 4 4 1 Hyaluronan / mRNA binding family API5 PF05918.6 CCM01952.1 - 0.48 8.8 23.9 0.017 13.6 2.6 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) PHD PF00628.24 CCM01953.1 - 8e-10 38.2 8.6 8e-10 38.2 6.0 2.2 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.3 CCM01953.1 - 1.3e-05 24.8 0.4 1.3e-05 24.8 0.3 2.2 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain LSM PF01423.17 CCM01954.1 - 2.4e-14 52.6 0.2 3.5e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain ETC_C1_NDUFA5 PF04716.9 CCM01955.1 - 7.4e-18 63.8 0.2 1.5e-17 62.8 0.2 1.5 2 0 0 2 2 2 1 ETC complex I subunit conserved region GTPase_Cys_C PF12631.2 CCM01955.1 - 0.11 12.9 0.1 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Thiolase_N PF00108.18 CCM01956.1 - 1.4e-68 230.7 0.2 2.5e-68 229.9 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCM01956.1 - 7e-41 138.5 0.3 2e-40 137.0 0.2 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 CCM01956.1 - 0.058 13.4 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 CCM01956.1 - 0.072 12.7 0.1 14 5.4 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_S3_C PF00189.15 CCM01957.1 - 9.3e-16 57.8 0.0 1.7e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CCM01957.1 - 2.8e-12 46.0 0.0 5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CCM01957.1 - 0.018 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 COX2-transmemb PF09125.5 CCM01958.1 - 0.059 12.9 3.7 0.18 11.3 2.6 1.9 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane DUF4131 PF13567.1 CCM01958.1 - 1 8.7 8.5 0.67 9.3 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4234 PF14018.1 CCM01958.1 - 7 6.4 8.9 48 3.7 6.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Mpp10 PF04006.7 CCM01959.1 - 2.9e-101 339.6 65.6 2.4e-100 336.6 45.5 2.0 1 1 0 1 1 1 1 Mpp10 protein Metal_resist PF13801.1 CCM01959.1 - 1.7 8.6 10.4 4.9 7.1 1.0 3.0 3 0 0 3 3 3 0 Heavy-metal resistance Daxx PF03344.10 CCM01959.1 - 2.3 6.5 52.6 0.11 10.9 14.3 2.5 2 1 0 2 2 2 0 Daxx Family SNARE PF05739.14 CCM01960.1 - 4.8e-08 32.5 1.7 4.8e-08 32.5 1.2 3.2 4 0 0 4 4 4 1 SNARE domain V-SNARE_C PF12352.3 CCM01960.1 - 0.00091 19.2 6.0 0.29 11.2 0.5 2.8 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Neur_chan_memb PF02932.11 CCM01960.1 - 0.4 10.5 4.0 0.24 11.2 0.9 1.8 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PBP1_TM PF14812.1 CCM01960.1 - 1.3 9.3 6.6 0.78 10.0 0.2 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HSCB_C PF07743.8 CCM01960.1 - 4.2 7.8 10.6 0.43 11.0 0.2 3.3 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain SAD_SRA PF02182.12 CCM01961.1 - 1.7e-34 118.3 0.0 2.4e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain Humanin PF15040.1 CCM01964.1 - 0.11 11.7 0.3 0.21 10.8 0.2 1.4 1 0 0 1 1 1 0 Humanin family PAP1 PF08601.5 CCM01964.1 - 5.8 6.5 10.8 6.8 6.2 7.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 UPF0160 PF03690.8 CCM01965.1 - 2.4e-117 391.9 0.0 4.9e-117 390.8 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) MARVEL PF01284.18 CCM01965.1 - 0.00032 20.5 2.9 0.00069 19.4 2.0 1.5 1 1 0 1 1 1 1 Membrane-associating domain Lipase_3 PF01764.20 CCM01966.1 - 9.2e-13 48.0 0.0 5.1e-12 45.5 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 CCM01966.1 - 0.0027 17.3 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCM01966.1 - 0.0095 15.8 0.4 0.018 14.9 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM01966.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CCM01966.1 - 0.034 13.7 0.2 0.084 12.4 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Esterase PF00756.15 CCM01966.1 - 0.049 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase MFS_1 PF07690.11 CCM01967.1 - 1.3e-20 73.4 21.2 1.3e-20 73.4 14.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM01967.1 - 0.16 10.5 15.8 1.5 7.3 10.9 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter Ribosomal_L15e PF00827.12 CCM01968.1 - 2.1e-90 301.3 13.1 2.6e-90 301.1 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 Glyco_hydro_16 PF00722.16 CCM01969.1 - 0.0012 18.2 0.2 0.0027 17.0 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF4450 PF14614.1 CCM01969.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) SurE PF01975.12 CCM01970.1 - 3.5e-09 36.2 0.0 4.9e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE RasGEF PF00617.14 CCM01971.1 - 2.2e-31 109.0 0.1 5.3e-31 107.8 0.1 1.6 1 1 0 1 1 1 1 RasGEF domain Ras PF00071.17 CCM01971.1 - 3.6e-07 29.7 0.0 2e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Ras family RasGEF_N PF00618.15 CCM01971.1 - 1.1e-06 28.6 0.0 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 CCM01971.1 - 1.5e-06 28.7 0.2 9.2e-06 26.1 0.1 2.2 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 CCM01971.1 - 0.087 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 CCM01971.1 - 0.16 12.7 3.3 0.61 10.9 1.0 2.8 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 CCM01972.1 - 3e-44 150.4 0.0 1.8e-42 144.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM01972.1 - 3.9e-25 87.5 0.0 8.7e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM01972.1 - 0.046 13.5 0.0 0.046 13.5 0.0 3.8 4 2 0 4 4 4 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CCM01972.1 - 0.053 11.9 0.0 0.3 9.4 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 CCM01972.1 - 0.058 13.5 0.1 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Apc4 PF12896.2 CCM01973.1 - 1.6e-34 119.0 0.0 3.1e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 bZIP_1 PF00170.16 CCM01974.1 - 0.00015 21.6 8.7 0.00061 19.7 5.9 2.1 1 1 0 1 1 1 1 bZIP transcription factor Rab5-bind PF09311.6 CCM01974.1 - 0.00058 19.8 0.2 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 Rabaptin-like protein DUF972 PF06156.8 CCM01974.1 - 0.0096 16.2 0.4 0.017 15.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF904 PF06005.7 CCM01974.1 - 0.0096 16.1 5.1 0.015 15.5 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF904) TBPIP PF07106.8 CCM01974.1 - 0.036 13.6 0.7 0.056 12.9 0.5 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Glutaredoxin2_C PF04399.8 CCM01974.1 - 0.07 12.7 1.8 0.12 11.9 1.2 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain AAA_13 PF13166.1 CCM01974.1 - 0.12 10.8 3.8 0.16 10.3 2.6 1.1 1 0 0 1 1 1 0 AAA domain SlyX PF04102.7 CCM01974.1 - 0.12 12.7 3.1 0.41 11.0 2.2 1.9 1 0 0 1 1 1 0 SlyX Med9 PF07544.8 CCM01974.1 - 0.13 11.9 1.6 0.38 10.5 1.1 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.14 CCM01974.1 - 0.22 9.3 0.5 0.3 8.9 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 CCM01974.1 - 0.32 10.8 6.8 0.03 14.1 1.4 1.7 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 CCM01974.1 - 0.34 10.4 4.0 0.54 9.8 2.8 1.2 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 CCM01974.1 - 0.49 9.2 5.8 0.8 8.5 4.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF641 PF04859.7 CCM01974.1 - 0.59 9.8 4.3 1.1 9.0 3.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) APG6 PF04111.7 CCM01974.1 - 0.78 8.7 3.0 1.1 8.2 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CCM01974.1 - 1.4 8.4 5.1 2.5 7.6 2.9 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF4164 PF13747.1 CCM01974.1 - 1.5 9.0 9.6 0.13 12.4 3.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) bZIP_2 PF07716.10 CCM01974.1 - 1.7 8.5 20.2 0.18 11.6 1.0 2.9 2 1 1 3 3 3 0 Basic region leucine zipper CR6_interact PF10147.4 CCM01974.1 - 6.2 6.0 9.4 15 4.8 6.5 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4355 PF14265.1 CCM01974.1 - 6.6 6.7 9.3 14 5.6 6.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) GPI2 PF06432.6 CCM01975.1 - 1.4e-79 267.3 14.6 1.6e-79 267.1 10.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Actin PF00022.14 CCM01977.1 - 5.9e-135 449.6 0.0 6.8e-135 449.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCM01977.1 - 0.053 12.1 0.0 0.39 9.2 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Ribosomal_S24e PF01282.14 CCM01978.1 - 3.9e-33 113.0 0.1 6.5e-33 112.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Tic20 PF09685.5 CCM01979.1 - 2.8e-05 24.0 0.6 4.2e-05 23.4 0.5 1.2 1 0 0 1 1 1 1 Tic20-like protein Vel1p PF10339.4 CCM01980.1 - 0.0042 16.2 0.1 0.0069 15.5 0.1 1.3 1 0 0 1 1 1 1 Yeast-specific zinc responsive HEAT PF02985.17 CCM01981.1 - 3.7e-46 151.0 16.3 0.001 18.9 0.0 13.5 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 CCM01981.1 - 4.1e-36 123.1 8.3 1.1e-09 38.3 0.0 6.5 2 1 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 CCM01981.1 - 5.7e-11 42.6 0.9 0.002 18.5 0.0 6.4 4 2 5 9 9 9 3 Vacuolar 14 Fab1-binding region Arm PF00514.18 CCM01981.1 - 7e-07 28.8 2.3 1.8 8.4 0.0 6.3 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CCM01981.1 - 1.6e-06 28.4 17.6 2.3 8.8 0.0 9.3 7 4 2 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.15 CCM01981.1 - 3.1e-06 25.7 1.2 0.0019 16.6 0.1 3.4 3 1 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.2 CCM01981.1 - 2.9e-05 23.9 0.5 0.003 17.4 0.0 4.1 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF1546 PF07571.8 CCM01981.1 - 0.0012 18.9 0.2 0.14 12.2 0.0 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF1546) HEAT_PBS PF03130.11 CCM01981.1 - 1.3 9.7 6.0 3.8 8.2 0.1 5.1 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Aldose_epim PF01263.15 CCM01982.1 - 2.2e-29 102.5 0.0 2.5e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Transaldolase PF00923.14 CCM01983.1 - 1.3e-13 50.7 0.0 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Transaldolase PIG-F PF06699.6 CCM01984.1 - 1.2e-21 77.5 8.9 1.8e-21 76.9 3.7 2.3 2 0 0 2 2 2 1 GPI biosynthesis protein family Pig-F Hydrolase_6 PF13344.1 CCM01985.1 - 1.3e-30 105.2 0.0 2.1e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCM01985.1 - 4.1e-16 58.4 0.0 8.4e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCM01985.1 - 1.9e-12 48.0 0.0 2.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCM01985.1 - 3.3e-08 33.9 0.1 0.00031 21.0 0.1 2.7 2 2 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HTHP PF11534.3 CCM01985.1 - 0.025 14.6 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Hexameric tyrosine-coordinated heme protein (HTHP) PGP_phosphatase PF09419.5 CCM01985.1 - 0.058 12.7 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Ribosomal_L7Ae PF01248.21 CCM01985.1 - 0.059 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L34e PF01199.13 CCM01986.1 - 1e-36 124.9 4.1 1.5e-36 124.4 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 CCM01986.1 - 0.21 11.2 1.6 13 5.5 0.2 2.7 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Ribosomal_L31e PF01198.14 CCM01987.1 - 2.4e-34 116.8 1.6 3.9e-34 116.1 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e Tetraspannin PF00335.15 CCM01987.1 - 0.00041 19.6 3.4 0.00041 19.6 2.3 1.5 1 1 0 1 1 1 1 Tetraspanin family CAP59_mtransfer PF11735.3 CCM01988.1 - 4.7e-71 238.8 0.0 6e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ion_trans PF00520.26 CCM01988.1 - 0.029 13.6 0.1 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Ion transport protein TerD PF02342.13 CCM01988.1 - 0.17 11.1 0.0 1.7 7.9 0.0 1.9 1 1 0 2 2 2 0 TerD domain VIT1 PF01988.14 CCM01991.1 - 6.7e-67 225.0 8.6 7.8e-67 224.8 6.0 1.0 1 0 0 1 1 1 1 VIT family Glyco_transf_90 PF05686.7 CCM01992.1 - 6.4e-14 51.4 0.6 9.5e-13 47.5 0.3 2.8 3 1 0 3 3 3 1 Glycosyl transferase family 90 N2227 PF07942.7 CCM01993.1 - 1.1e-75 254.0 0.2 9.4e-63 211.7 0.0 2.1 2 0 0 2 2 2 2 N2227-like protein Methyltransf_23 PF13489.1 CCM01993.1 - 4.5e-05 23.2 0.0 8.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM01993.1 - 0.0082 16.6 0.0 0.029 14.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FRG2 PF15315.1 CCM01993.1 - 0.04 13.8 2.7 0.07 13.0 1.9 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Methyltransf_11 PF08241.7 CCM01993.1 - 0.08 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Zip PF02535.17 CCM01993.1 - 0.7 8.8 5.9 0.99 8.3 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF550 PF04447.7 CCM01994.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF550) JAB PF01398.16 CCM01996.1 - 3.1e-16 59.1 0.0 5.2e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CCM01996.1 - 7.8e-08 31.8 0.0 2e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Molybdopterin PF00384.17 CCM01997.1 - 2.8e-63 214.1 0.0 3.3e-61 207.3 0.0 2.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 CCM01997.1 - 1e-19 70.1 0.3 3.6e-19 68.3 0.2 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 CCM01997.1 - 3e-19 67.9 0.1 1.2e-18 66.0 0.1 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 CCM01997.1 - 5.9e-17 61.5 0.2 1.6e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 CCM01997.1 - 1.4e-08 34.3 0.7 1.4e-08 34.3 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 CCM01997.1 - 0.049 14.2 0.1 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4 PF00037.22 CCM01997.1 - 0.081 12.5 1.1 4 7.1 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 CCM01997.1 - 0.25 11.2 2.4 0.46 10.4 0.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Sugar_tr PF00083.19 CCM01999.1 - 9.1e-99 331.0 22.7 1.2e-98 330.6 15.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM01999.1 - 3e-27 95.2 28.2 4.5e-27 94.7 19.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CCM01999.1 - 3.2e-05 22.3 3.0 3.2e-05 22.3 2.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CCM01999.1 - 0.0029 15.7 5.3 0.0072 14.4 1.8 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector ABC_membrane PF00664.18 CCM02000.1 - 1.4e-67 228.0 24.7 4.9e-40 137.6 5.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCM02000.1 - 2.6e-63 212.3 0.0 1.1e-30 106.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCM02000.1 - 3.6e-17 62.3 7.6 6.2e-07 28.8 0.6 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCM02000.1 - 9.4e-11 42.5 0.0 0.00088 20.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 CCM02000.1 - 1.4e-10 41.6 0.0 0.11 12.4 0.0 4.2 3 1 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 CCM02000.1 - 1.4e-09 37.0 0.5 0.00045 18.9 0.1 3.2 4 0 0 4 4 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 CCM02000.1 - 5.9e-09 36.1 0.8 0.0048 17.0 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCM02000.1 - 4.2e-08 33.3 5.2 4.5e-05 23.5 0.1 3.9 5 0 0 5 5 3 2 AAA ATPase domain AAA_18 PF13238.1 CCM02000.1 - 9.8e-08 32.3 0.0 0.0091 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCM02000.1 - 2.1e-07 30.3 0.1 0.034 13.6 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.12 CCM02000.1 - 4.4e-07 29.4 0.0 1 8.7 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF258 PF03193.11 CCM02000.1 - 7.4e-07 28.4 0.0 0.022 13.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 CCM02000.1 - 2.4e-06 27.5 0.2 0.0056 16.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_10 PF12846.2 CCM02000.1 - 3.4e-06 26.7 2.0 0.38 10.1 0.0 4.2 6 0 0 6 6 3 1 AAA-like domain Zeta_toxin PF06414.7 CCM02000.1 - 1.7e-05 24.0 0.0 0.14 11.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 CCM02000.1 - 2.9e-05 23.9 0.0 0.092 12.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCM02000.1 - 3.2e-05 23.8 0.0 0.08 12.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CCM02000.1 - 0.00012 21.6 0.0 0.16 11.3 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_19 PF13245.1 CCM02000.1 - 0.00017 21.2 0.7 0.61 9.8 0.0 3.8 4 0 0 4 4 2 1 Part of AAA domain SbcCD_C PF13558.1 CCM02000.1 - 0.00021 21.1 0.7 1.1 9.2 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 CCM02000.1 - 0.00021 21.0 0.1 1.5 8.5 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCM02000.1 - 0.00069 19.0 0.0 1.6 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 CCM02000.1 - 0.00083 19.0 0.0 0.73 9.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CCM02000.1 - 0.00089 18.8 0.5 1.1 8.8 0.1 3.4 3 1 0 3 3 3 1 AAA domain APS_kinase PF01583.15 CCM02000.1 - 0.0013 18.3 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF2075 PF09848.4 CCM02000.1 - 0.0015 17.5 0.8 0.31 9.9 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 CCM02000.1 - 0.002 17.7 0.0 0.36 10.3 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 CCM02000.1 - 0.0021 17.9 0.0 4.8 7.1 0.0 3.6 4 0 0 4 4 3 0 50S ribosome-binding GTPase AAA_23 PF13476.1 CCM02000.1 - 0.0039 17.5 0.1 0.83 9.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.1 CCM02000.1 - 0.0061 16.6 0.0 9.9 6.2 0.0 3.8 4 0 0 4 4 3 0 Sigma-54 interaction domain Thymidylate_kin PF02223.12 CCM02000.1 - 0.0064 15.8 0.1 1.3 8.3 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase Mg_chelatase PF01078.16 CCM02000.1 - 0.0064 15.6 0.0 3.3 6.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCM02000.1 - 0.0072 16.2 0.0 5.9 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CCM02000.1 - 0.01 16.3 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 CCM02000.1 - 0.011 15.9 0.0 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 CCM02000.1 - 0.022 13.5 0.2 2.8 6.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.21 CCM02000.1 - 0.027 13.9 0.1 7.8 5.9 0.0 3.1 4 0 0 4 4 3 0 Sigma-54 interaction domain DUF3987 PF13148.1 CCM02000.1 - 0.028 12.9 0.1 4.6 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) G-alpha PF00503.15 CCM02000.1 - 0.035 12.7 0.0 2.7 6.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.7 CCM02000.1 - 0.04 13.5 0.6 12 5.5 0.0 2.9 3 0 0 3 3 2 0 NACHT domain CbiA PF01656.18 CCM02000.1 - 0.068 12.5 0.1 10 5.5 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 CCM02000.1 - 0.077 12.6 0.2 3.2 7.4 0.0 2.8 2 0 0 2 2 2 0 NTPase CoaE PF01121.15 CCM02000.1 - 0.094 12.1 2.6 9.1 5.6 0.0 2.9 3 0 0 3 3 2 0 Dephospho-CoA kinase Rop-like PF05082.8 CCM02000.1 - 0.11 12.0 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Rop-like AAA_13 PF13166.1 CCM02000.1 - 0.26 9.6 0.5 11 4.3 0.0 3.0 4 0 0 4 4 4 0 AAA domain DUF1680 PF07944.7 CCM02001.1 - 3.1e-25 88.4 5.7 7.9e-25 87.1 4.0 1.5 1 1 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Toxin_trans PF07952.7 CCM02001.1 - 0.28 10.0 0.1 1.4 7.7 0.0 1.8 1 1 1 2 2 2 0 Clostridium neurotoxin, Translocation domain Tetraspannin PF00335.15 CCM02001.1 - 9.7 5.3 0.1 16 4.6 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family adh_short_C2 PF13561.1 CCM02002.1 - 4.3e-32 111.8 0.8 6.1e-32 111.3 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCM02002.1 - 1.8e-31 109.2 1.4 2.8e-31 108.6 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM02002.1 - 7e-18 64.9 0.4 1.1e-17 64.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM02002.1 - 1.4e-09 37.7 0.2 1.8e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM02002.1 - 0.0056 16.7 0.7 0.011 15.7 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 CCM02002.1 - 0.044 12.8 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.12 CCM02002.1 - 0.067 12.0 0.9 0.13 11.1 0.4 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain ABC2_membrane PF01061.19 CCM02003.1 - 5.4e-77 257.6 60.7 8.7e-43 145.9 10.6 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CCM02003.1 - 6e-38 130.2 0.0 1.1e-17 64.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCM02003.1 - 8.1e-38 128.2 9.5 1.2e-30 105.2 0.0 2.9 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CCM02003.1 - 4.9e-14 52.1 0.1 1.2e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCM02003.1 - 5.6e-06 25.8 0.0 0.01 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCM02003.1 - 1.1e-05 24.7 0.5 0.00031 19.9 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCM02003.1 - 4e-05 23.6 0.1 0.075 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CCM02003.1 - 4.6e-05 23.5 0.0 0.43 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCM02003.1 - 8e-05 22.9 0.0 0.17 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 CCM02003.1 - 0.00046 19.6 0.3 0.65 9.4 0.6 2.9 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 CCM02003.1 - 0.00072 20.3 0.0 1.2 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM02003.1 - 0.0014 18.3 0.2 3 7.6 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain PduV-EutP PF10662.4 CCM02003.1 - 0.0015 18.0 0.1 1.2 8.6 0.1 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_3 PF12698.2 CCM02003.1 - 0.0028 16.7 25.7 0.0028 16.7 17.8 3.4 2 2 0 3 3 3 2 ABC-2 family transporter protein UPF0079 PF02367.12 CCM02003.1 - 0.0035 16.9 0.7 1.4 8.5 0.2 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 CCM02003.1 - 0.0039 16.6 0.8 0.057 12.9 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CCM02003.1 - 0.0074 16.0 0.0 0.88 9.2 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 CCM02003.1 - 0.0086 16.0 0.3 3.3 7.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCM02003.1 - 0.011 15.3 0.1 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 CCM02003.1 - 0.014 15.3 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 CCM02003.1 - 0.016 15.0 0.0 7.1 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 CCM02003.1 - 0.04 13.8 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCM02003.1 - 0.047 13.1 0.1 5.8 6.2 0.2 2.7 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 CCM02003.1 - 0.063 13.4 0.1 17 5.6 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CCM02003.1 - 0.093 12.3 0.2 4.9 6.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CCM02003.1 - 0.12 12.3 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 CCM02003.1 - 0.12 11.5 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 CCM02003.1 - 0.12 11.4 0.0 2.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 CCM02003.1 - 0.14 12.6 0.0 20 5.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 CCM02003.1 - 0.21 11.8 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TBCC PF07986.7 CCM02004.1 - 9.8e-24 83.0 0.1 1.7e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C zf-rbx1 PF12678.2 CCM02005.1 - 3.8e-35 119.8 13.4 4.6e-35 119.5 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCM02005.1 - 8.5e-17 60.7 9.6 1.1e-16 60.4 6.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CCM02005.1 - 2.4e-07 30.4 12.2 1.2e-06 28.1 8.5 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCM02005.1 - 0.00082 18.9 11.8 0.015 14.9 8.2 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCM02005.1 - 0.0025 17.8 3.4 0.0025 17.8 2.4 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCM02005.1 - 0.0036 16.9 9.7 0.014 15.0 2.8 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CCM02005.1 - 0.38 10.7 9.5 2.1 8.3 6.7 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 CCM02005.1 - 0.91 9.5 9.6 2.8 7.9 6.7 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCM02005.1 - 0.98 9.6 10.8 59 3.9 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 CCM02005.1 - 0.98 9.1 7.2 1.3 8.8 1.7 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 CCM02005.1 - 1.2 8.8 11.4 9.2 6.0 7.9 2.3 1 1 0 1 1 1 0 zinc-RING finger domain SURF6 PF04935.7 CCM02006.1 - 2.2e-39 134.9 43.8 2.2e-39 134.9 30.3 2.7 3 0 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 CCM02006.1 - 1.2e-05 25.2 4.8 1.2e-05 25.2 3.3 5.8 5 1 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 Cation_efflux PF01545.16 CCM02007.1 - 4.2e-10 39.1 0.7 1.7e-09 37.1 0.5 1.8 1 1 0 1 1 1 1 Cation efflux family PTPA PF03095.10 CCM02008.1 - 9.4e-120 399.3 0.0 1.2e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Cu-oxidase_2 PF07731.9 CCM02009.1 - 7.7e-37 125.8 10.8 3.2e-35 120.6 0.4 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 CCM02009.1 - 4.1e-35 121.0 1.1 5.5e-35 120.6 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCM02009.1 - 7.3e-35 119.2 7.3 3.9e-32 110.4 0.7 3.6 3 0 0 3 3 3 2 Multicopper oxidase RskA PF10099.4 CCM02009.1 - 0.015 15.0 0.1 0.038 13.7 0.1 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Phosphoesterase PF04185.9 CCM02010.1 - 2.7e-24 86.0 4.7 4.2e-24 85.4 3.3 1.3 1 0 0 1 1 1 1 Phosphoesterase family F-box-like PF12937.2 CCM02013.1 - 0.00013 21.6 0.8 0.00036 20.1 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM02013.1 - 0.0002 20.9 0.3 0.00055 19.5 0.2 1.7 1 0 0 1 1 1 1 F-box domain p450 PF00067.17 CCM02014.1 - 1.1e-62 212.0 0.0 2.3e-62 211.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 GAS PF13851.1 CCM02015.1 - 0.00085 18.5 1.1 0.67 9.1 0.0 2.9 3 0 0 3 3 3 2 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 CCM02015.1 - 0.0012 17.4 2.5 0.0018 16.8 1.8 1.2 1 0 0 1 1 1 1 AAA domain E2R135 PF11570.3 CCM02015.1 - 0.0022 18.1 10.4 0.034 14.2 0.1 3.0 2 1 1 3 3 3 2 Coiled-coil receptor-binding R-domain of colicin E2 Bacillus_HBL PF05791.6 CCM02015.1 - 0.03 13.6 0.3 0.32 10.3 0.0 2.4 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Tmemb_cc2 PF10267.4 CCM02015.1 - 0.041 12.4 2.0 3.7 6.0 0.0 2.4 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein FliJ PF02050.11 CCM02015.1 - 0.049 13.6 8.0 3.4 7.7 0.1 3.5 3 1 0 3 3 3 0 Flagellar FliJ protein Rab5-bind PF09311.6 CCM02015.1 - 0.074 12.9 5.8 2.7 7.8 1.2 2.5 2 0 0 2 2 2 0 Rabaptin-like protein DUF4201 PF13870.1 CCM02015.1 - 0.23 10.8 4.7 0.29 10.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) IncA PF04156.9 CCM02015.1 - 0.42 10.1 3.5 7.1 6.1 0.0 3.0 3 0 0 3 3 3 0 IncA protein IFT57 PF10498.4 CCM02015.1 - 2.3 6.8 4.8 8.1 5.0 0.1 2.6 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 T2SF PF00482.18 CCM02016.1 - 0.039 13.8 0.0 0.26 11.1 0.0 2.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F UPF0259 PF06790.6 CCM02016.1 - 0.041 13.3 0.9 0.08 12.3 0.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0259) SlyX PF04102.7 CCM02016.1 - 0.11 12.8 2.4 0.77 10.1 0.2 3.1 2 0 0 2 2 2 0 SlyX Cluap1 PF10234.4 CCM02016.1 - 0.25 10.4 11.3 0.35 10.0 0.9 3.3 3 0 0 3 3 3 0 Clusterin-associated protein-1 Seryl_tRNA_N PF02403.17 CCM02016.1 - 0.68 9.9 15.7 0.5 10.3 0.3 3.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain AAA_27 PF13514.1 CCM02016.1 - 1.3 6.6 16.6 0.84 7.2 5.7 3.1 3 1 0 3 3 3 0 AAA domain LOH1CR12 PF10158.4 CCM02016.1 - 1.9 8.2 7.2 0.18 11.6 0.4 2.7 3 0 0 3 3 3 0 Tumour suppressor protein DivIC PF04977.10 CCM02016.1 - 3.2 7.2 8.2 14 5.2 0.4 3.3 2 1 0 2 2 2 0 Septum formation initiator OmpH PF03938.9 CCM02016.1 - 3.3 7.6 18.0 0.087 12.7 0.7 3.6 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) IncA PF04156.9 CCM02016.1 - 7.5 6.0 11.2 16 5.0 0.0 3.6 4 1 0 4 4 4 0 IncA protein T2SF PF00482.18 CCM02017.1 - 0.036 13.9 0.9 0.2 11.5 0.1 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F B12-binding_2 PF02607.12 CCM02017.1 - 0.11 12.5 0.1 19 5.3 0.0 3.8 4 0 0 4 4 4 0 B12 binding domain Filament PF00038.16 CCM02017.1 - 0.27 10.6 10.7 3.4 7.0 0.3 3.2 3 0 0 3 3 3 0 Intermediate filament protein GLE1 PF07817.8 CCM02017.1 - 0.78 8.6 12.4 2.7 6.8 2.2 2.6 2 0 0 2 2 2 0 GLE1-like protein IncA PF04156.9 CCM02017.1 - 1.2 8.6 14.4 0.12 11.9 1.0 3.5 4 0 0 4 4 4 0 IncA protein ECH_C PF13766.1 CCM02017.1 - 2.9 8.0 0.0 2.9 8.0 0.0 4.5 5 1 0 5 5 5 0 2-enoyl-CoA Hydratase C-terminal region AIP3 PF03915.8 CCM02017.1 - 7.3 5.3 16.4 0.047 12.5 1.6 2.9 3 0 0 3 3 3 0 Actin interacting protein 3 UBA PF00627.26 CCM02018.1 - 0.026 14.3 0.4 0.084 12.7 0.3 1.9 1 0 0 1 1 1 0 UBA/TS-N domain AAA_13 PF13166.1 CCM02018.1 - 0.21 10.0 11.5 0.28 9.5 8.0 1.3 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 CCM02018.1 - 0.59 9.9 13.0 5.6 6.8 0.1 4.7 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding HrpF PF06266.7 CCM02018.1 - 2.4 8.3 9.7 1.4 9.1 0.1 3.0 3 0 0 3 3 3 0 HrpF protein DUF4600 PF15372.1 CCM02018.1 - 3.6 7.8 8.4 2.7 8.1 2.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) adh_short PF00106.20 CCM02019.1 - 9.5e-30 103.7 0.1 1.3e-29 103.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM02019.1 - 3.3e-14 52.9 0.1 5.4e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM02019.1 - 2.7e-11 43.7 0.0 4.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCM02019.1 - 0.0025 17.3 0.0 0.0044 16.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CCM02019.1 - 0.0075 15.1 0.0 0.0096 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CCM02019.1 - 0.1 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Imm2 PF14426.1 CCM02021.1 - 0.032 14.2 0.3 0.046 13.7 0.1 1.3 1 1 0 1 1 1 0 Immunity protein Imm2 Methyltransf_25 PF13649.1 CCM02022.1 - 1.4e-07 31.8 0.0 5.7e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM02022.1 - 0.097 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_3 PF13302.1 CCM02023.1 - 9.2e-10 38.8 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM02023.1 - 1e-05 25.4 0.0 3.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCM02023.1 - 0.14 11.8 0.0 6.6 6.5 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein OPT PF03169.10 CCM02024.1 - 3.2e-133 445.4 50.0 3.7e-133 445.2 34.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DHO_dh PF01180.16 CCM02025.1 - 2.3e-91 305.8 0.0 2.9e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CCM02025.1 - 0.00032 19.6 0.1 0.00053 18.9 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 CCM02025.1 - 0.011 14.9 0.2 0.022 13.9 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase PcrB PF01884.12 CCM02025.1 - 0.018 14.3 0.2 4.4 6.4 0.0 2.4 2 0 0 2 2 2 0 PcrB family DNA_circ_N PF07157.7 CCM02025.1 - 0.065 13.3 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 DNA circularisation protein N-terminus Abhydrolase_4 PF08386.5 CCM02026.1 - 8.4e-19 67.3 0.0 1.3e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 CCM02026.1 - 1.7e-10 40.8 0.0 3.6e-09 36.5 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCM02026.1 - 6e-09 36.1 0.0 7.2e-08 32.5 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM02026.1 - 0.018 14.8 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family WES_acyltransf PF03007.11 CCM02027.1 - 1e-24 87.5 0.0 2.3e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Peptidase_S15 PF02129.13 CCM02027.1 - 0.017 14.5 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MelC1 PF06236.6 CCM02027.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Dehydrin PF00257.14 CCM02029.1 - 3.4 7.9 6.4 5.5 7.2 4.4 1.3 1 0 0 1 1 1 0 Dehydrin Whi5 PF08528.6 CCM02030.1 - 6.1e-06 25.7 1.0 1.3e-05 24.6 0.7 1.6 1 0 0 1 1 1 1 Whi5 like Aldo_ket_red PF00248.16 CCM02031.1 - 1.2e-55 188.4 0.0 1.3e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NUDIX PF00293.23 CCM02032.1 - 0.00068 19.2 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Aldo_ket_red PF00248.16 CCM02033.1 - 9.3e-65 218.2 0.0 1.1e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myosin_tail_1 PF01576.14 CCM02035.1 - 0.017 12.8 2.9 0.033 11.9 2.0 1.4 1 0 0 1 1 1 0 Myosin tail DUF3452 PF11934.3 CCM02035.1 - 0.13 11.5 0.7 1.1 8.5 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) DUF2968 PF11180.3 CCM02035.1 - 0.22 10.8 5.3 0.052 12.9 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) GAS PF13851.1 CCM02035.1 - 0.25 10.5 7.3 0.15 11.2 2.3 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 CCM02035.1 - 0.42 10.5 2.5 5.4 7.0 0.3 3.2 3 0 0 3 3 3 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 CCM02035.1 - 0.66 10.0 8.8 2.8 7.9 0.8 3.7 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF904 PF06005.7 CCM02035.1 - 0.84 9.9 7.9 0.87 9.9 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 CCM02035.1 - 1.9 8.4 7.0 0.56 10.1 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DivIVA PF05103.8 CCM02035.1 - 2.1 8.3 7.2 15 5.6 0.1 3.5 4 0 0 4 4 4 0 DivIVA protein DivIC PF04977.10 CCM02035.1 - 2.1 7.8 7.5 0.9 9.0 0.6 3.1 3 0 0 3 3 3 0 Septum formation initiator Mod_r PF07200.8 CCM02035.1 - 3.4 7.5 11.5 0.5 10.2 1.4 3.3 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein CDC37_N PF03234.9 CCM02036.1 - 0.007 16.7 0.8 0.018 15.3 0.6 1.8 1 1 0 1 1 1 1 Cdc37 N terminal kinase binding Exonuc_X-T_C PF08411.5 CCM02036.1 - 0.033 13.2 2.4 0.92 8.4 0.3 2.2 1 1 0 2 2 2 0 Exonuclease C-terminal Syntaxin_2 PF14523.1 CCM02036.1 - 0.066 13.2 1.0 1.5 8.8 0.7 2.3 2 0 0 2 2 2 0 Syntaxin-like protein PEP-utilisers_N PF05524.8 CCM02036.1 - 0.097 12.4 3.7 0.2 11.4 0.6 2.2 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Baculo_PEP_C PF04513.7 CCM02036.1 - 0.13 12.0 0.6 0.41 10.4 0.1 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 CCM02036.1 - 0.35 10.7 6.0 0.3 10.9 0.4 2.4 2 1 0 2 2 2 0 Tropomyosin like DSS1_SEM1 PF05160.8 CCM02036.1 - 1.3 8.8 6.1 3.8 7.3 0.6 2.6 2 0 0 2 2 2 0 DSS1/SEM1 family Prefoldin PF02996.12 CCM02036.1 - 3.4 7.3 9.1 4.1 7.0 0.4 3.3 3 1 1 4 4 4 0 Prefoldin subunit Phage_lysis PF03245.8 CCM02037.1 - 0.011 15.7 0.8 0.1 12.5 0.4 1.9 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Peptidase_S10 PF00450.17 CCM02038.1 - 1.8e-101 340.3 0.0 2.3e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCM02038.1 - 0.00022 21.2 0.0 0.0042 17.0 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-Apc11 PF12861.2 CCM02038.1 - 0.031 14.1 1.4 0.063 13.1 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Aldo_ket_red PF00248.16 CCM02039.1 - 1.2e-62 211.3 0.0 1.4e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AsnA PF03590.10 CCM02039.1 - 0.044 13.2 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Aspartate-ammonia ligase Complex1_LYR_1 PF13232.1 CCM02042.1 - 2.7e-14 53.0 1.8 3.3e-14 52.8 1.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CCM02042.1 - 3.3e-11 42.8 0.7 4.2e-11 42.4 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Pkinase PF00069.20 CCM02043.1 - 6.5e-41 140.1 0.0 1e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02043.1 - 4.5e-20 71.8 0.0 7.4e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM02043.1 - 5e-10 38.8 0.0 9.5e-09 34.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCM02043.1 - 0.003 17.3 3.8 0.067 12.9 2.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCM02043.1 - 0.036 13.1 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CCM02043.1 - 0.085 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Phage_lysis PF03245.8 CCM02046.1 - 0.008 16.1 0.4 0.071 13.1 0.2 1.9 2 0 0 2 2 2 1 Bacteriophage Rz lysis protein CDC37_N PF03234.9 CCM02047.1 - 0.047 14.0 0.1 0.088 13.1 0.0 1.6 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding GCN5L1 PF06320.8 CCM02047.1 - 0.086 12.6 1.7 0.49 10.2 0.0 2.6 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) PEP-utilisers_N PF05524.8 CCM02047.1 - 0.37 10.6 3.5 0.67 9.7 0.6 2.2 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal IncA PF04156.9 CCM02048.1 - 0.00033 20.3 12.2 0.015 14.8 0.0 3.3 2 1 1 3 3 3 2 IncA protein DUF4407 PF14362.1 CCM02048.1 - 0.0044 16.0 0.4 0.0044 16.0 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) ChitinaseA_N PF08329.5 CCM02048.1 - 0.01 15.5 0.2 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Tropomyosin_1 PF12718.2 CCM02048.1 - 0.015 15.1 3.3 0.015 15.1 2.3 3.1 3 0 0 3 3 3 0 Tropomyosin like DUF1488 PF07369.6 CCM02048.1 - 0.032 14.0 0.6 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) GAS PF13851.1 CCM02048.1 - 0.057 12.6 12.2 0.071 12.3 2.8 3.3 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding MerR-DNA-bind PF09278.6 CCM02048.1 - 0.16 12.3 1.8 2.8 8.4 0.0 3.2 3 0 0 3 3 3 0 MerR, DNA binding COG2 PF06148.6 CCM02048.1 - 0.24 11.2 7.5 1.1 9.1 0.5 2.9 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 CCM02048.1 - 0.51 10.1 3.6 2.6 7.8 0.5 3.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 CCM02048.1 - 0.52 10.2 11.1 0.16 11.8 0.5 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 CCM02048.1 - 1.4 9.1 10.1 23 5.3 0.1 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 CCM02048.1 - 2.2 8.0 8.6 3 7.6 0.2 3.5 3 1 1 4 4 4 0 Laminin Domain II Seryl_tRNA_N PF02403.17 CCM02048.1 - 2.2 8.3 12.4 8.7 6.4 3.3 3.7 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Phage_lysis PF03245.8 CCM02048.1 - 2.6 8.0 7.0 1.4 8.9 0.7 3.1 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein Microtub_assoc PF07989.6 CCM02048.1 - 3.5 7.5 9.9 0.46 10.3 3.0 2.4 2 0 0 2 2 2 0 Microtubule associated bZIP_1 PF00170.16 CCM02048.1 - 5.2 7.0 9.5 6.2 6.8 0.2 3.8 3 1 0 3 3 3 0 bZIP transcription factor TMF_DNA_bd PF12329.3 CCM02048.1 - 7.8 6.3 11.6 0.61 9.9 0.6 3.5 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding FMN_dh PF01070.13 CCM02050.1 - 3.7e-103 345.0 0.0 4.9e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 CCM02050.1 - 2.5e-06 26.8 1.7 3.8e-06 26.2 1.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 CCM02050.1 - 0.0001 21.4 0.2 0.00015 20.7 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CCM02050.1 - 0.00026 19.9 0.4 0.00056 18.8 0.1 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 CCM02050.1 - 0.00078 18.4 0.7 0.0064 15.4 0.0 2.1 1 1 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 CCM02050.1 - 0.0048 16.0 1.4 0.17 10.9 0.1 2.5 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CCM02050.1 - 0.019 14.2 0.3 0.097 11.9 0.2 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein DHH PF01368.15 CCM02051.1 - 6.6e-10 38.8 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.9 CCM02051.1 - 8.4e-09 35.6 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain Abhydrolase_6 PF12697.2 CCM02052.1 - 1.8e-22 80.3 0.1 2.5e-22 79.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM02052.1 - 9.1e-21 74.1 0.0 1.6e-20 73.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCM02052.1 - 2.2e-15 56.2 0.2 4.7e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CCM02052.1 - 1.6e-06 27.8 0.0 3.3e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM02052.1 - 3.5e-06 26.3 0.0 0.0029 16.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 CCM02052.1 - 1.9e-05 24.0 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PhoPQ_related PF10142.4 CCM02052.1 - 0.00011 20.8 0.0 0.00018 20.0 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.7 CCM02052.1 - 0.0015 17.0 0.1 0.23 9.9 0.0 2.3 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Thioesterase PF00975.15 CCM02052.1 - 0.02 15.1 0.2 0.054 13.7 0.1 1.8 1 1 0 1 1 1 0 Thioesterase domain LIP PF03583.9 CCM02052.1 - 0.11 11.6 0.0 9.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase AMP-binding PF00501.23 CCM02055.1 - 3.5e-73 246.3 2.9 1.2e-72 244.5 2.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCM02055.1 - 2.9e-08 34.5 0.1 7.9e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GPI-anchored PF10342.4 CCM02056.1 - 0.0044 17.4 0.1 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family p450 PF00067.17 CCM02057.1 - 2.2e-56 191.3 0.0 2.9e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TH1 PF04858.8 CCM02058.1 - 0.058 11.5 0.0 0.089 10.9 0.0 1.2 1 0 0 1 1 1 0 TH1 protein PMSR PF01625.16 CCM02060.1 - 2.6e-54 183.3 0.3 5e-54 182.4 0.2 1.4 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase UCR_hinge PF02320.11 CCM02060.1 - 7.9e-10 38.5 1.3 1.8e-09 37.4 0.9 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Ribosomal_60s PF00428.14 CCM02060.1 - 0.62 10.4 14.0 1.8 9.0 9.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein CT47 PF15623.1 CCM02060.1 - 2.5 7.7 16.3 4 7.1 11.3 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 IATP PF04568.7 CCM02062.1 - 6.9e-06 26.0 3.7 6.9e-06 26.0 2.5 2.0 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP T2SM PF04612.7 CCM02062.1 - 0.0061 16.3 0.6 0.0063 16.3 0.4 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M HSA PF07529.8 CCM02063.1 - 4.9e-16 58.2 1.2 4.9e-16 58.2 0.8 4.2 4 1 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 CCM02063.1 - 1.6e-11 44.1 0.2 5.4e-11 42.4 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCM02063.1 - 3.5e-06 26.9 0.2 9.4e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SMI1_KNR4 PF09346.5 CCM02064.1 - 1.2e-24 86.7 0.0 1.8e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) CoA_trans PF01144.18 CCM02065.1 - 2.9e-94 314.2 5.6 5.1e-55 186.0 0.4 2.1 2 0 0 2 2 2 2 Coenzyme A transferase CoA_trans PF01144.18 CCM02066.1 - 2e-104 347.5 2.5 1.5e-58 197.5 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CCM02066.1 - 0.0031 17.1 0.1 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Cofilin_ADF PF00241.15 CCM02067.1 - 1.3e-20 73.5 0.0 4e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein FYVE PF01363.16 CCM02068.1 - 5.9e-17 61.3 2.5 1e-16 60.5 1.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUF4206 PF13901.1 CCM02068.1 - 0.013 15.0 0.7 0.032 13.7 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) zf-C2HC5 PF06221.8 CCM02068.1 - 0.037 13.8 7.5 0.018 14.8 3.3 1.8 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.11 CCM02068.1 - 0.14 12.0 3.7 0.14 12.0 1.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger Rbsn PF11464.3 CCM02068.1 - 0.15 11.6 0.7 0.32 10.5 0.5 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain SOG2 PF10428.4 CCM02069.1 - 2.8e-50 171.2 0.1 2.8e-50 171.2 0.1 2.9 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 CCM02069.1 - 2.9e-12 45.8 0.1 1.1e-05 24.9 0.0 3.5 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM02069.1 - 2.3e-09 36.8 0.8 9.9e-06 25.2 0.2 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CCM02069.1 - 2e-06 27.0 0.3 0.74 10.0 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CCM02069.1 - 4.1e-05 23.1 0.3 34 5.2 0.0 5.4 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 CCM02069.1 - 0.15 12.2 0.9 8 6.8 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat PNTB PF02233.11 CCM02070.1 - 1.8e-119 399.5 30.9 1.8e-119 399.5 21.4 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_N PF05222.10 CCM02070.1 - 9.1e-45 152.0 0.1 2.1e-44 150.8 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CCM02070.1 - 1.5e-33 115.7 0.0 2.8e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF3814 PF12769.2 CCM02070.1 - 2.3e-32 110.9 4.0 2.3e-32 110.9 2.8 4.6 5 2 1 7 7 7 1 Domain of unknown function (DUF3814) Git3 PF11710.3 CCM02070.1 - 0.11 12.1 0.2 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TruB_N PF01509.13 CCM02071.1 - 2.3e-23 82.9 0.6 3.3e-12 46.8 0.5 3.1 1 1 2 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) HSP70 PF00012.15 CCM02072.1 - 2.5e-65 220.5 2.3 2.8e-65 220.4 1.6 1.0 1 0 0 1 1 1 1 Hsp70 protein AAA_23 PF13476.1 CCM02072.1 - 0.067 13.5 1.5 0.087 13.1 1.0 1.2 1 0 0 1 1 1 0 AAA domain Porin_3 PF01459.17 CCM02073.1 - 7.8e-71 238.5 3.3 1e-70 238.1 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic porin ABC_tran PF00005.22 CCM02074.1 - 6.1e-26 91.3 0.0 1.1e-25 90.4 0.0 1.4 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 CCM02074.1 - 6.3e-07 29.6 0.0 0.015 15.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CCM02074.1 - 1.5e-06 27.5 0.0 0.0002 20.6 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CCM02074.1 - 1.8e-06 27.3 0.0 0.0004 19.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 CCM02074.1 - 7.1e-05 22.6 0.1 0.00089 19.1 0.0 2.6 2 1 0 2 2 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CCM02074.1 - 0.0002 20.8 0.0 0.00043 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCM02074.1 - 0.00025 21.1 0.0 0.00079 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM02074.1 - 0.00027 21.0 0.2 0.00035 20.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CCM02074.1 - 0.00029 20.0 0.0 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CCM02074.1 - 0.0005 20.4 0.0 0.0009 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCM02074.1 - 0.00072 20.3 0.1 0.0034 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CCM02074.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CCM02074.1 - 0.0022 17.6 0.1 0.0059 16.2 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 CCM02074.1 - 0.0023 17.6 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCM02074.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCM02074.1 - 0.0051 17.1 0.0 0.0093 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CCM02074.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 CCM02074.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 CCM02074.1 - 0.033 13.5 0.0 0.083 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 CCM02074.1 - 0.049 12.2 0.1 0.67 8.4 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.18 CCM02074.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 CCM02074.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CCM02074.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 CCM02074.1 - 0.12 12.8 0.2 0.25 11.8 0.0 1.6 2 0 0 2 2 1 0 Miro-like protein Viral_helicase1 PF01443.13 CCM02074.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_13 PF13166.1 CCM02074.1 - 0.16 10.4 0.0 8.9 4.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF972 PF06156.8 CCM02075.1 - 0.00092 19.5 14.5 0.00096 19.4 0.7 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF972) DUF2205 PF10224.4 CCM02075.1 - 0.0022 17.5 0.9 0.0022 17.5 0.6 3.5 4 0 0 4 4 4 1 Predicted coiled-coil protein (DUF2205) CSTF2_hinge PF14327.1 CCM02075.1 - 0.023 14.7 3.0 0.074 13.1 2.1 1.8 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DNA_primase_lrg PF04104.9 CCM02075.1 - 0.04 13.1 0.1 0.04 13.1 0.1 2.1 2 1 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit GAS PF13851.1 CCM02075.1 - 0.055 12.6 10.8 0.13 11.4 0.7 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 CCM02075.1 - 0.065 13.1 5.4 0.5 10.2 0.2 3.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Adenylsucc_synt PF00709.16 CCM02075.1 - 0.1 11.2 2.0 0.9 8.1 0.1 2.2 2 0 0 2 2 2 0 Adenylosuccinate synthetase DivIC PF04977.10 CCM02075.1 - 0.13 11.7 0.2 0.13 11.7 0.1 3.7 3 1 0 3 3 3 0 Septum formation initiator Syntaxin-6_N PF09177.6 CCM02075.1 - 0.37 11.2 16.8 2.8 8.4 2.4 4.2 3 2 1 4 4 4 0 Syntaxin 6, N-terminal MutS_IV PF05190.13 CCM02075.1 - 0.39 10.9 6.7 2.5 8.3 0.7 3.4 3 0 0 3 3 3 0 MutS family domain IV AAA_13 PF13166.1 CCM02075.1 - 0.69 8.2 11.3 2.7 6.3 6.1 2.3 1 1 0 2 2 2 0 AAA domain YojJ PF10372.4 CCM02075.1 - 0.88 9.4 5.5 1.7 8.5 0.5 3.2 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus MitMem_reg PF13012.1 CCM02075.1 - 1.2 9.2 12.2 0.44 10.6 1.6 3.7 4 0 0 4 4 4 0 Maintenance of mitochondrial structure and function Herpes_BLRF2 PF05812.7 CCM02075.1 - 1.2 8.9 8.9 0.24 11.2 0.3 3.1 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 CCM02075.1 - 4.1 7.4 8.3 1 9.3 0.4 3.8 3 1 0 3 3 3 0 bZIP transcription factor IncA PF04156.9 CCM02075.1 - 4.6 6.7 26.7 0.32 10.5 3.6 3.5 2 2 1 3 3 3 0 IncA protein DUF4140 PF13600.1 CCM02075.1 - 5.6 7.4 14.2 11 6.5 3.7 3.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Prominin PF05478.6 CCM02075.1 - 9.2 3.6 10.8 5.5 4.3 0.5 2.5 2 1 0 2 2 2 0 Prominin Nuc_sug_transp PF04142.10 CCM02077.1 - 1.4e-59 201.2 5.1 1.4e-59 201.2 3.5 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 CCM02077.1 - 1.1e-07 31.6 9.5 3.8e-06 26.6 1.6 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CCM02077.1 - 1.1e-07 31.9 0.5 1.1e-07 31.9 0.4 3.0 4 0 0 4 4 4 1 Multidrug resistance efflux transporter UAA PF08449.6 CCM02077.1 - 7.1e-07 28.4 2.1 1e-06 27.8 0.7 1.7 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 CCM02077.1 - 6.9e-05 22.8 4.6 6.9e-05 22.8 3.2 2.8 2 2 0 2 2 2 1 EamA-like transporter family Exo_endo_phos PF03372.18 CCM02078.1 - 2.4e-16 60.4 0.0 3.5e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OTU PF02338.14 CCM02079.1 - 8e-10 39.3 0.0 1.3e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.18 CCM02079.1 - 0.014 14.7 0.2 0.13 11.6 0.1 2.3 1 1 0 1 1 1 0 Ubiquitin family Antitoxin-MazE PF04014.13 CCM02079.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Tom37_C PF11801.3 CCM02080.1 - 3.7e-13 49.7 0.2 6.5e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 CCM02080.1 - 1.3e-08 35.0 0.1 2.6e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 CCM02080.1 - 0.00054 19.7 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TAFII55_N PF04658.8 CCM02081.1 - 7e-55 184.9 0.7 1.5e-54 183.8 0.5 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region Daxx PF03344.10 CCM02081.1 - 7.6 4.8 25.5 9.9 4.5 16.0 2.1 2 0 0 2 2 2 0 Daxx Family Gaa1 PF04114.9 CCM02082.1 - 1e-69 235.6 6.9 4.6e-68 230.1 4.8 2.3 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component LUC7 PF03194.10 CCM02082.1 - 3.1e-36 125.2 12.7 1.4e-35 123.0 0.2 2.3 2 0 0 2 2 2 2 LUC7 N_terminus DnaJ PF00226.26 CCM02082.1 - 1e-13 50.7 0.2 3.2e-13 49.2 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.2 CCM02082.1 - 1.2e-09 38.3 0.1 3.8e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCM02082.1 - 2.5e-09 37.3 0.1 1.1e-08 35.3 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CCM02082.1 - 8.3e-08 31.6 0.2 0.0069 16.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCM02082.1 - 1.2e-05 25.0 0.1 0.24 11.7 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCM02082.1 - 0.00026 21.1 0.1 0.017 15.3 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) FRG1 PF06229.7 CCM02083.1 - 3.3e-27 95.1 0.1 3.3e-27 95.1 0.1 1.6 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 CCM02083.1 - 0.00032 20.7 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 Fascin domain KOW PF00467.24 CCM02084.1 - 4.3e-09 35.7 3.8 4.3e-09 35.7 2.6 2.1 2 0 0 2 2 2 1 KOW motif DUF2636 PF11120.3 CCM02084.1 - 0.076 12.5 0.2 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) ATP-synt_D PF01813.12 CCM02085.1 - 1.1e-65 220.8 2.9 1.6e-65 220.3 2.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit D XAP5 PF04921.9 CCM02086.1 - 4.7e-94 314.4 5.8 4.7e-94 314.4 4.0 2.2 2 0 0 2 2 2 1 XAP5, circadian clock regulator Acyl-CoA_ox_N PF14749.1 CCM02086.1 - 0.41 10.9 6.3 0.039 14.2 0.9 1.8 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Herpes_UL95 PF03038.9 CCM02086.1 - 0.85 8.4 5.0 0.55 9.0 2.3 1.5 1 1 1 2 2 2 0 UL95 family TRAPP PF04051.11 CCM02087.1 - 3.4e-33 114.2 0.0 4.8e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PTP_N PF12453.3 CCM02087.1 - 0.079 12.5 0.2 0.079 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal UCH PF00443.24 CCM02089.1 - 3.4e-30 105.0 0.2 3.4e-30 105.0 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM02089.1 - 2.5e-14 53.4 0.3 6.6e-14 52.0 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CCM02089.1 - 1.2e-07 31.0 0.1 3.1e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.7 CCM02089.1 - 4.7e-05 23.7 0.0 0.039 14.3 0.0 3.2 3 0 0 3 3 3 1 DUSP domain zf-RanBP PF00641.13 CCM02089.1 - 0.0015 17.5 4.5 0.0015 17.5 3.1 2.5 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others zf-FPG_IleRS PF06827.9 CCM02089.1 - 0.07 12.7 4.6 4.2 7.1 0.1 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Methyltransf_11 PF08241.7 CCM02090.1 - 6.8e-09 36.0 0.0 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.3 CCM02090.1 - 9.6e-08 32.4 1.0 1.7e-07 31.5 0.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_23 PF13489.1 CCM02090.1 - 2.3e-05 24.1 0.0 5.3e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM02090.1 - 0.00014 21.4 0.0 0.00034 20.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM02090.1 - 0.00054 20.3 0.0 0.0016 18.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM02090.1 - 0.00054 20.5 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM02090.1 - 0.0021 18.3 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM02090.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.17 CCM02091.1 - 1.4e-47 161.0 0.0 1.9e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM02091.1 - 3.2e-14 53.4 0.0 5.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM02091.1 - 3e-08 33.0 0.0 4.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCM02091.1 - 0.023 13.8 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region STAS PF01740.16 CCM02091.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 STAS domain G-alpha PF00503.15 CCM02091.1 - 0.35 9.4 1.6 2.9 6.4 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit MFS_1 PF07690.11 CCM02092.1 - 1.5e-49 168.6 50.7 1.5e-49 168.6 35.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCM02092.1 - 1.2e-16 60.0 16.1 2e-16 59.3 11.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCM02092.1 - 2.4e-14 52.7 13.4 2.4e-14 52.7 9.3 3.1 2 2 1 3 3 3 1 Sugar (and other) transporter IncA PF04156.9 CCM02092.1 - 0.22 11.0 3.1 0.69 9.4 2.1 1.8 1 0 0 1 1 1 0 IncA protein DUF4231 PF14015.1 CCM02092.1 - 1.7 8.6 13.0 0.088 12.8 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Vac_ImportDeg PF09783.4 CCM02093.1 - 3.9e-54 182.8 0.0 1.6e-52 177.5 0.0 2.1 2 0 0 2 2 2 2 Vacuolar import and degradation protein Pkinase PF00069.20 CCM02094.1 - 9.8e-33 113.3 0.0 1.3e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02094.1 - 3.9e-12 45.7 0.0 5.5e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM02094.1 - 0.00038 20.2 0.1 0.55 9.9 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF1439 PF07273.7 CCM02094.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) JmjC PF02373.17 CCM02095.1 - 3.8e-12 46.4 0.0 9.2e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase GAS PF13851.1 CCM02096.1 - 0.029 13.5 1.5 0.043 13.0 1.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding LEA_2 PF03168.8 CCM02097.1 - 4.5e-05 23.7 0.1 9.1e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 CCM02097.1 - 0.00016 20.9 1.4 0.00025 20.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Vac7 PF12751.2 CCM02097.1 - 0.0013 17.7 0.4 0.002 17.0 0.3 1.2 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF726 PF05277.7 CCM02098.1 - 1e-80 271.2 1.8 1.6e-80 270.5 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 CCM02098.1 - 0.00053 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_8 PF06259.7 CCM02098.1 - 0.00063 19.2 0.3 0.0019 17.7 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase Cutinase PF01083.17 CCM02098.1 - 0.0053 16.5 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Cutinase Gate PF07670.9 CCM02098.1 - 0.036 13.9 0.5 0.25 11.2 0.2 2.5 2 1 1 3 3 3 0 Nucleoside recognition Abhydrolase_6 PF12697.2 CCM02098.1 - 0.047 13.5 1.9 0.1 12.4 0.1 2.2 2 1 1 3 3 3 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM02098.1 - 0.059 13.1 0.1 0.25 11.0 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_M41 PF01434.13 CCM02099.1 - 3.6e-66 222.6 0.1 5.9e-66 221.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CCM02099.1 - 1.5e-43 148.1 0.0 3.1e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCM02099.1 - 7.3e-06 26.8 0.0 2.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM02099.1 - 5.3e-05 23.2 1.6 0.0056 16.6 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CCM02099.1 - 6.9e-05 22.6 0.1 0.00044 19.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CCM02099.1 - 8.7e-05 21.6 0.0 0.00027 20.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CCM02099.1 - 0.00016 20.5 0.0 0.00029 19.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 CCM02099.1 - 0.00099 19.2 3.7 0.015 15.4 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 CCM02099.1 - 0.0012 18.5 0.7 0.0012 18.5 0.5 2.4 2 0 0 2 2 1 1 Part of AAA domain IstB_IS21 PF01695.12 CCM02099.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CCM02099.1 - 0.0024 17.7 0.0 0.0076 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCM02099.1 - 0.0031 17.4 0.0 0.015 15.1 0.0 2.2 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CCM02099.1 - 0.0038 16.4 0.3 0.0087 15.2 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCM02099.1 - 0.0044 16.9 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCM02099.1 - 0.0081 15.2 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CCM02099.1 - 0.014 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCM02099.1 - 0.015 14.7 5.5 0.069 12.5 0.6 3.1 3 1 1 4 4 4 0 AAA domain NACHT PF05729.7 CCM02099.1 - 0.017 14.7 1.2 0.15 11.6 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_14 PF13173.1 CCM02099.1 - 0.03 14.2 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 CCM02099.1 - 0.13 11.1 0.0 0.27 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_pol_Rpb2_6 PF00562.23 CCM02100.1 - 6.5e-106 354.3 0.6 6.3e-104 347.7 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCM02100.1 - 2.3e-55 186.6 0.0 5.2e-55 185.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCM02100.1 - 8.5e-31 106.8 0.0 2.4e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCM02100.1 - 9.4e-25 86.6 0.0 3.4e-24 84.9 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCM02100.1 - 1.8e-22 78.9 1.8 3.1e-22 78.1 0.7 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCM02100.1 - 2.5e-21 75.1 0.0 6.8e-21 73.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCM02100.1 - 4.7e-13 48.8 0.1 1.1e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Caa3_CtaG PF09678.5 CCM02100.1 - 0.27 10.1 0.1 0.42 9.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) UQ_con PF00179.21 CCM02101.1 - 2.6e-47 159.7 0.0 3e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCM02101.1 - 0.098 12.4 0.0 0.34 10.6 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B UPF0261 PF06792.6 CCM02102.1 - 9.8e-139 462.2 0.1 1.1e-138 462.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 CCM02103.1 - 2.6e-134 446.4 0.4 2.9e-134 446.2 0.2 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 CCM02103.1 - 0.0012 18.0 0.2 0.0017 17.5 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Got1 PF04178.7 CCM02105.1 - 6e-24 84.4 10.5 8.5e-24 83.9 7.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Colicin_V PF02674.11 CCM02105.1 - 7.8 6.3 14.5 3 7.6 2.7 2.4 2 1 0 2 2 2 0 Colicin V production protein DUF3414 PF11894.3 CCM02106.1 - 4.4e-258 859.3 0.0 5.9e-258 858.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Acetyltransf_1 PF00583.19 CCM02107.1 - 1.2e-15 57.2 0.0 1.7e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCM02107.1 - 5.1e-08 32.5 0.0 7.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCM02107.1 - 1.3e-07 31.7 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCM02107.1 - 9e-07 28.8 0.0 1.3e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCM02107.1 - 1.5e-06 28.2 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCM02107.1 - 5.4e-06 26.6 0.0 6.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCM02107.1 - 8.9e-05 22.3 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HSP70 PF00012.15 CCM02108.1 - 6.4e-266 883.0 3.4 7.3e-266 882.8 2.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCM02108.1 - 1.4e-19 69.9 0.2 1.4e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 CCM02108.1 - 0.00048 19.0 0.6 0.045 12.5 0.3 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 CCM02108.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Spectrin PF00435.16 CCM02108.1 - 0.16 12.2 5.3 5.5 7.3 0.0 3.4 3 1 1 4 4 4 0 Spectrin repeat Hydantoinase_A PF01968.13 CCM02108.1 - 0.36 9.8 5.8 0.065 12.3 0.3 2.3 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 CCM02108.1 - 2.7 7.8 4.9 37 4.1 0.2 3.7 2 1 0 2 2 2 0 Cell division protein FtsA AA_permease_2 PF13520.1 CCM02109.1 - 2.3e-61 207.6 57.2 3e-61 207.2 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCM02109.1 - 6.1e-16 57.8 52.5 3.2e-15 55.4 36.4 1.8 1 1 0 1 1 1 1 Amino acid permease DUF4293 PF14126.1 CCM02109.1 - 0.056 13.3 0.2 0.056 13.3 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) 4HBT PF03061.17 CCM02110.1 - 1.2e-05 25.3 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Sina PF03145.11 CCM02111.1 - 0.0033 17.1 0.9 1.8 8.1 0.1 2.1 1 1 1 2 2 2 2 Seven in absentia protein family DNA_pol_viral_N PF00242.12 CCM02111.1 - 0.85 8.5 8.2 1.4 7.8 5.7 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CCM02111.1 - 5.4 5.1 12.5 7.8 4.6 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 CCM02112.1 - 3.9e-49 167.1 0.0 6.2e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02112.1 - 1.4e-47 161.9 0.0 1.9e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CCM02112.1 - 3.5e-08 33.0 0.8 6.3e-08 32.2 0.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 CCM02112.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PHD PF00628.24 CCM02112.1 - 0.016 14.9 2.2 0.029 14.0 1.5 1.4 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 CCM02112.1 - 0.06 13.3 0.6 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 C1-like domain Kinase-like PF14531.1 CCM02112.1 - 0.063 12.2 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like C1_2 PF03107.11 CCM02112.1 - 0.065 13.3 1.8 0.12 12.5 1.3 1.5 1 0 0 1 1 1 0 C1 domain Prok-RING_1 PF14446.1 CCM02112.1 - 0.087 12.5 4.1 0.18 11.5 2.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Kdo PF06293.9 CCM02112.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cluap1 PF10234.4 CCM02115.1 - 0.018 14.2 0.7 0.021 14.0 0.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 CKAP2_C PF15297.1 CCM02115.1 - 0.022 13.5 0.2 0.031 13.1 0.2 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus EBV-NA3 PF05009.7 CCM02115.1 - 0.043 13.0 0.2 0.073 12.3 0.0 1.4 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Rap_GAP PF02145.10 CCM02116.1 - 1.1e-44 152.0 0.0 2e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 CCM02116.1 - 5.6e-26 91.4 0.9 9e-24 84.1 0.0 2.8 3 0 0 3 3 3 2 Tuberin SF-assemblin PF06705.6 CCM02116.1 - 6.1 5.9 4.9 1.3 8.1 0.9 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin XPG_I PF00867.13 CCM02117.1 - 5.2e-19 68.0 0.0 1.4e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCM02117.1 - 0.00062 19.9 0.0 0.0018 18.5 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain CTP_transf_2 PF01467.21 CCM02118.1 - 4.8e-12 46.2 0.0 1.8e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase SapA PF02199.10 CCM02118.1 - 0.049 13.4 0.6 0.099 12.4 0.4 1.5 1 0 0 1 1 1 0 Saposin A-type domain Alpha-amylase PF00128.19 CCM02119.1 - 1.8e-06 27.5 0.0 2.2e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain adh_short PF00106.20 CCM02120.1 - 0.0007 19.5 0.1 2.3 8.1 0.0 3.3 3 1 1 4 4 4 2 short chain dehydrogenase Metallophos PF00149.23 CCM02121.1 - 4e-40 137.3 0.1 4.9e-40 137.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Methyltransf_31 PF13847.1 CCM02122.1 - 3.6e-17 62.3 0.0 5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCM02122.1 - 2.8e-15 56.1 0.0 3.7e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 CCM02122.1 - 1.2e-14 54.5 0.1 3.5e-14 53.0 0.1 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM02122.1 - 3.5e-14 53.3 0.1 7.9e-14 52.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM02122.1 - 4e-10 39.6 0.0 5.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM02122.1 - 5.4e-09 36.3 0.3 1.1e-08 35.3 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM02122.1 - 1.9e-08 34.6 0.0 4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM02122.1 - 4.7e-08 33.0 0.6 2.9e-07 30.5 0.4 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM02122.1 - 1.1e-07 31.2 0.1 1.7e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 CCM02122.1 - 2.4e-05 23.5 0.0 3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.7 CCM02122.1 - 4e-05 23.0 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Sterol_MT_C PF08498.5 CCM02122.1 - 0.00016 21.5 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal PCMT PF01135.14 CCM02122.1 - 0.0002 20.9 0.1 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CCM02122.1 - 0.00054 19.3 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 CCM02122.1 - 0.001 17.8 0.0 0.0016 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 CCM02122.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCM02122.1 - 0.0041 16.2 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 CCM02122.1 - 0.0047 16.9 0.1 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 CCM02122.1 - 0.0072 17.1 0.0 0.015 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CCM02122.1 - 0.0097 15.4 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase NodS PF05401.6 CCM02122.1 - 0.012 14.9 0.1 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) Pox_MCEL PF03291.11 CCM02122.1 - 0.019 13.8 0.1 0.027 13.3 0.1 1.1 1 0 0 1 1 1 0 mRNA capping enzyme UPF0020 PF01170.13 CCM02122.1 - 0.026 14.0 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 CCM02122.1 - 0.05 12.6 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 CCM02122.1 - 0.098 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase VHS PF00790.14 CCM02123.1 - 1.6e-14 53.7 0.0 2.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CCM02123.1 - 1.1e-08 34.9 0.2 0.0019 18.1 0.0 2.4 2 0 0 2 2 2 2 GAT domain DUF1294 PF06961.8 CCM02123.1 - 0.098 12.6 0.1 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) RRM_1 PF00076.17 CCM02124.1 - 4.5e-36 122.3 0.1 3.7e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM02124.1 - 3.3e-30 103.8 0.0 8e-17 60.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM02124.1 - 4.8e-14 51.9 0.0 2e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CCM02124.1 - 0.016 14.7 0.1 0.72 9.4 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Mito_fiss_reg PF05308.6 CCM02124.1 - 0.24 10.7 7.6 0.39 10.0 5.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator HEAT_2 PF13646.1 CCM02125.1 - 2.9e-11 43.4 6.1 0.074 13.3 0.0 7.7 6 2 1 7 7 7 3 HEAT repeats VHS PF00790.14 CCM02125.1 - 0.00093 18.8 0.3 0.0071 15.9 0.0 2.5 2 0 0 2 2 2 1 VHS domain HEAT PF02985.17 CCM02125.1 - 0.0013 18.6 12.4 0.35 11.0 0.0 7.7 9 0 0 9 9 9 2 HEAT repeat SMC_N PF02463.14 CCM02130.1 - 2.3e-63 213.3 0.5 4.7e-63 212.3 0.4 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCM02130.1 - 9.3e-32 109.5 6.2 1e-31 109.3 0.0 3.3 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCM02130.1 - 1.2e-14 54.9 0.3 1.9e-06 28.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCM02130.1 - 4.6e-07 29.2 0.0 9.6e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sec8_exocyst PF04048.9 CCM02130.1 - 3.4e-06 26.7 9.0 3.4e-06 26.7 6.3 6.1 4 1 1 6 6 6 1 Sec8 exocyst complex component specific domain SbcCD_C PF13558.1 CCM02130.1 - 0.0009 19.1 0.0 0.004 17.0 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CCM02130.1 - 0.024 13.6 0.0 0.024 13.6 0.0 5.1 4 1 1 5 5 5 0 AAA ATPase domain ABC_tran PF00005.22 CCM02130.1 - 0.086 13.1 0.0 0.086 13.1 0.0 5.6 4 1 0 5 5 5 0 ABC transporter Reo_sigmaC PF04582.7 CCM02130.1 - 0.23 10.5 24.1 0.55 9.3 1.7 5.2 5 0 0 5 5 5 0 Reovirus sigma C capsid protein Abhydrolase_3 PF07859.8 CCM02131.1 - 2.5e-66 223.2 0.0 3.1e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CCM02131.1 - 3.8e-09 35.8 0.1 8.8e-09 34.5 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 CCM02131.1 - 2.2e-07 29.8 0.0 3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCM02131.1 - 6.8e-06 25.8 0.0 1e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCM02131.1 - 1.5e-05 24.2 0.0 0.00056 19.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 CCM02131.1 - 0.00024 20.0 0.0 0.00033 19.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme UDP-g_GGTase PF06427.6 CCM02132.1 - 5.6e-50 169.5 0.0 1.3e-49 168.4 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CCM02132.1 - 2.5e-07 30.2 0.1 4.4e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Oxidored_FMN PF00724.15 CCM02133.1 - 3.2e-71 240.1 0.0 4e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SGL PF08450.7 CCM02135.1 - 5.7e-22 78.2 0.0 1.1e-21 77.3 0.0 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CCM02135.1 - 2.3e-06 27.5 0.0 1.6e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 CCM02135.1 - 0.001 18.9 0.0 0.0034 17.3 0.0 1.9 1 0 0 1 1 1 1 Arylesterase adh_short_C2 PF13561.1 CCM02136.1 - 6.7e-36 124.2 0.8 7.7e-36 124.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCM02136.1 - 7.4e-26 91.0 3.0 9.1e-26 90.7 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM02136.1 - 4.3e-10 39.5 1.0 6.5e-10 38.9 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM02136.1 - 8.4e-07 28.6 0.2 2.8e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CCM02136.1 - 8.9e-06 25.0 0.0 1.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.10 CCM02136.1 - 0.012 15.2 2.4 0.072 12.6 1.6 2.1 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.12 CCM02136.1 - 0.065 13.6 0.7 0.14 12.6 0.5 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1906 PF08924.6 CCM02136.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Ubie_methyltran PF01209.13 CCM02136.1 - 0.078 12.0 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MIP-T3 PF10243.4 CCM02137.1 - 1.1 7.5 8.2 1.3 7.3 5.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MAP7 PF05672.6 CCM02137.1 - 5.1 6.4 28.3 0.99 8.7 15.2 2.0 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family NPR3 PF03666.8 CCM02137.1 - 8.5 4.7 8.2 11 4.3 5.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 E1-E2_ATPase PF00122.15 CCM02138.1 - 2.4e-59 200.1 0.1 2.4e-59 200.1 0.1 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCM02138.1 - 4.6e-22 79.5 0.2 9.7e-22 78.4 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCM02138.1 - 3e-13 49.0 0.1 7.3e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CCM02138.1 - 3.5e-13 50.1 0.1 1.1e-12 48.5 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCM02138.1 - 0.0002 21.0 0.0 0.00045 19.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Choline_transpo PF04515.7 CCM02140.1 - 7.2e-24 84.1 9.8 2.4e-23 82.4 6.8 1.9 1 1 0 1 1 1 1 Plasma-membrane choline transporter Spt5_N PF11942.3 CCM02141.1 - 0.54 10.9 7.3 4 8.1 1.5 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Aa_trans PF01490.13 CCM02143.1 - 3.9e-37 127.7 34.1 5.7e-37 127.1 23.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PDH PF02153.12 CCM02143.1 - 2.9e-13 49.3 0.0 4.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 CCM02143.1 - 0.0016 18.2 0.3 0.0043 16.8 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCM02143.1 - 0.029 14.7 0.0 0.079 13.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 CCM02143.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CCM02143.1 - 0.15 11.1 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_N PF02776.13 CCM02144.1 - 1.3e-58 197.3 0.2 2.6e-57 193.0 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCM02144.1 - 3.7e-47 159.7 0.7 6.1e-45 152.5 0.1 2.9 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCM02144.1 - 1.4e-36 125.2 1.7 2.1e-36 124.6 0.3 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain FAA_hydrolase PF01557.13 CCM02145.1 - 2.4e-54 184.0 0.0 3.2e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2848 PF11010.3 CCM02145.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) DsrH PF04077.7 CCM02145.1 - 0.075 12.7 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 DsrH like protein UCR_Fe-S_N PF10399.4 CCM02146.1 - 0.014 14.5 9.0 0.037 13.2 6.2 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Defensin_big PF14862.1 CCM02146.1 - 1.5 8.9 5.1 1.2 9.2 1.1 2.2 2 0 0 2 2 2 0 Big defensin Shisa PF13908.1 CCM02147.1 - 0.00071 19.7 0.1 0.00091 19.4 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1191 PF06697.7 CCM02147.1 - 0.00087 18.1 0.1 0.0011 17.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF2668 PF10873.3 CCM02147.1 - 0.001 19.2 0.1 0.0014 18.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) DUF2561 PF10812.3 CCM02147.1 - 0.001 18.6 2.9 0.0017 17.9 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) 7tm_1 PF00001.16 CCM02147.1 - 0.0022 17.1 0.0 0.0028 16.8 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM51 PF15345.1 CCM02147.1 - 0.0025 17.5 0.1 0.0028 17.4 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Herpes_gE PF02480.11 CCM02147.1 - 0.0037 15.5 0.1 0.0044 15.3 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E UPF0104 PF03706.8 CCM02147.1 - 0.0076 15.5 0.2 0.0089 15.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) TMEM154 PF15102.1 CCM02147.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF456 PF04306.8 CCM02147.1 - 0.02 14.9 0.5 0.028 14.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) CD34_antigen PF06365.7 CCM02147.1 - 0.022 14.4 0.1 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family NicO PF03824.11 CCM02147.1 - 0.026 13.8 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF4448 PF14610.1 CCM02147.1 - 0.029 13.8 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Amnionless PF14828.1 CCM02147.1 - 0.031 12.7 0.0 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless 7TM_GPCR_Srz PF10325.4 CCM02147.1 - 0.039 13.0 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Ctr PF04145.10 CCM02147.1 - 0.043 13.8 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF3609 PF12259.3 CCM02147.1 - 0.047 12.3 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Rhabdo_glycop PF00974.13 CCM02147.1 - 0.05 11.8 0.1 0.06 11.5 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein EphA2_TM PF14575.1 CCM02147.1 - 0.053 13.9 0.4 0.11 12.9 0.1 1.7 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.1 CCM02147.1 - 0.056 13.5 0.1 0.092 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SieB PF14163.1 CCM02147.1 - 0.06 12.9 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF1218 PF06749.7 CCM02147.1 - 0.066 13.6 0.6 0.099 13.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) DUF106 PF01956.11 CCM02147.1 - 0.079 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF912 PF06024.7 CCM02147.1 - 0.081 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM52 PF14979.1 CCM02147.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane 52 DUF485 PF04341.7 CCM02147.1 - 0.11 12.1 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 SIT PF15330.1 CCM02147.1 - 0.13 12.4 0.4 0.23 11.6 0.0 1.7 2 0 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT Rifin_STEVOR PF02009.11 CCM02147.1 - 0.15 11.6 0.1 0.19 11.3 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family Glycophorin_A PF01102.13 CCM02147.1 - 0.21 11.3 1.5 0.23 11.2 0.1 1.8 1 1 1 2 2 2 0 Glycophorin A Protocadherin PF08374.6 CCM02147.1 - 0.54 9.8 3.0 0.24 10.9 0.5 1.6 1 1 0 1 1 1 0 Protocadherin DUF3995 PF13160.1 CCM02147.1 - 0.86 9.6 4.2 2.1 8.4 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) UPF0233 PF06781.7 CCM02147.1 - 1.1 8.9 4.5 0.44 10.2 0.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) HemY_N PF07219.8 CCM02147.1 - 2.6 7.6 6.1 0.14 11.7 0.5 1.7 2 0 0 2 2 1 0 HemY protein N-terminus Sensor PF13796.1 CCM02147.1 - 7.8 6.0 10.3 1.8 8.1 2.9 1.9 1 1 1 2 2 2 0 Putative sensor RCR PF12273.3 CCM02147.1 - 8.5 6.9 7.7 2.1 8.8 3.1 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF2749 PF10907.3 CCM02147.1 - 8.9 6.2 10.4 17 5.3 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2749) EAP30 PF04157.11 CCM02149.1 - 5.2e-55 186.0 0.0 5.9e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family HTH_15 PF12324.3 CCM02149.1 - 0.076 12.6 0.1 0.34 10.5 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Pec_lyase_N PF04431.8 CCM02150.1 - 0.033 14.2 0.2 0.074 13.1 0.2 1.6 1 0 0 1 1 1 0 Pectate lyase, N terminus DDHD PF02862.12 CCM02150.1 - 1.5 8.5 8.9 2.2 8.0 6.2 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 CCM02150.1 - 7.3 6.4 10.0 12 5.7 6.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 INCENP_ARK-bind PF03941.10 CCM02151.1 - 4.4e-18 64.8 0.5 3e-17 62.2 0.3 2.6 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region adh_short PF00106.20 CCM02152.1 - 9.8e-20 71.1 0.0 1.4e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM02152.1 - 2.3e-07 30.6 0.0 1.1e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM02152.1 - 2.1e-05 24.4 0.0 2.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM02152.1 - 0.00019 21.5 0.0 0.00033 20.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM02152.1 - 0.004 16.6 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CCM02152.1 - 0.0073 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CCM02152.1 - 0.077 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 CCM02152.1 - 0.088 11.9 0.0 1.4 8.0 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) RNase_PH PF01138.16 CCM02154.1 - 9e-12 45.4 0.2 2e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCM02154.1 - 0.0084 16.0 0.1 0.19 11.6 0.0 2.5 3 0 0 3 3 3 1 3' exoribonuclease family, domain 2 HMG_box PF00505.14 CCM02155.1 - 1.8e-10 40.9 0.0 3.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM02155.1 - 0.053 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 HMG-box domain SOG2 PF10428.4 CCM02155.1 - 9.2 4.7 11.2 0.29 9.7 2.6 1.9 2 0 0 2 2 2 0 RAM signalling pathway protein AMP-binding PF00501.23 CCM02157.1 - 2.7e-30 105.1 0.0 2.1e-28 98.8 0.0 2.5 3 0 0 3 3 3 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCM02157.1 - 5.9e-29 100.7 0.1 8.5e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CCM02157.1 - 4.5e-10 39.3 0.1 1e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CCM02157.1 - 0.0027 17.6 0.5 0.0056 16.5 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM02157.1 - 0.0035 17.0 0.9 0.0074 15.9 0.3 1.7 2 0 0 2 2 2 1 KR domain DUF1778 PF08681.6 CCM02157.1 - 0.013 15.2 0.0 5.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) PP-binding PF00550.20 CCM02157.1 - 0.034 14.4 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 Phosphopantetheine attachment site CbiX PF01903.12 CCM02157.1 - 0.097 12.7 0.0 9.1 6.4 0.0 2.9 2 0 0 2 2 2 0 CbiX 3Beta_HSD PF01073.14 CCM02157.1 - 0.099 11.3 0.1 1.4 7.5 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2480 PF10652.4 CCM02157.1 - 0.13 11.8 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2480) ICMT PF04140.9 CCM02158.1 - 8.1e-13 48.3 0.1 6.8e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM02158.1 - 2.4e-12 46.8 0.1 2.7e-11 43.4 0.1 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CCM02158.1 - 3.6e-08 32.3 0.1 5.3e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CCM02158.1 - 0.046 13.0 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ICMT PF04140.9 CCM02159.1 - 0.00016 21.8 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM02159.1 - 0.039 14.0 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipid methyltransferase DUF3188 PF11384.3 CCM02159.1 - 0.11 12.1 1.1 0.17 11.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) ICMT PF04140.9 CCM02160.1 - 2.6e-13 49.9 0.3 3e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM02160.1 - 1.8e-10 40.8 1.3 1.8e-09 37.6 0.9 2.2 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CCM02160.1 - 4.8e-07 28.6 0.2 7e-07 28.1 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF2296 PF10058.4 CCM02161.1 - 6.7e-20 70.5 0.2 2.7e-19 68.6 0.2 1.9 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) zf-RanBP PF00641.13 CCM02161.1 - 0.06 12.4 1.0 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Zn_Tnp_IS1595 PF12760.2 CCM02161.1 - 0.19 11.5 0.9 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CCM02161.1 - 1.2 8.7 5.3 5.3 6.6 3.7 1.9 1 1 1 2 2 2 0 A2L zinc ribbon domain Abhydrolase_6 PF12697.2 CCM02162.1 - 6.8e-21 75.1 3.5 9.7e-21 74.6 2.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM02162.1 - 4.4e-07 29.7 5.1 1.2e-06 28.2 3.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM02162.1 - 0.00075 19.1 0.6 0.0025 17.4 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mycobact_memb PF05423.8 CCM02166.1 - 0.14 11.9 1.5 0.4 10.4 0.2 2.0 2 0 0 2 2 2 0 Mycobacterium membrane protein Transket_pyr PF02779.19 CCM02167.1 - 5.8e-59 198.5 0.0 9.3e-59 197.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CCM02167.1 - 5.3e-43 146.8 0.0 8.8e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DEAD PF00270.24 CCM02168.1 - 4.1e-20 71.9 0.0 8e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCM02168.1 - 1.9e-07 31.1 0.0 1.2e-06 28.4 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCM02168.1 - 1.6e-05 24.6 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 CCM02168.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Aldo_ket_red PF00248.16 CCM02169.1 - 5.7e-46 156.5 0.0 6.8e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ICMT PF04140.9 CCM02170.1 - 1.1e-12 48.0 1.4 1.2e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM02170.1 - 2.5e-12 46.8 0.1 2.5e-12 46.8 0.1 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 CCM02170.1 - 0.0019 17.5 0.0 0.0034 16.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CCM02171.1 - 2.8e-13 49.8 0.1 1.9e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM02171.1 - 1.6e-11 44.2 0.3 4.2e-11 42.8 0.2 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CCM02171.1 - 5e-08 31.8 0.2 7e-08 31.4 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CCM02171.1 - 2.3e-05 23.8 0.1 3.3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CCM02172.1 - 7.6e-29 99.7 0.6 2.4e-13 50.0 0.0 3.2 4 0 0 4 4 4 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM02172.1 - 2.8e-23 82.0 1.8 4.6e-11 42.7 0.1 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase DUF1295 PF06966.7 CCM02172.1 - 7.4e-12 45.0 0.2 6.1e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 CCM02172.1 - 4.9e-10 38.5 4.9 9.9e-08 30.9 0.2 2.2 2 0 0 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 CCM02172.1 - 3.5e-06 26.8 0.1 0.046 13.4 0.0 2.7 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1335 PF07056.6 CCM02172.1 - 0.00048 19.8 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1335) HAD PF12710.2 CCM02173.1 - 1.8e-12 47.8 0.2 3.4e-12 46.9 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCM02173.1 - 2.8e-06 27.6 0.0 6.1e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 CCM02173.1 - 0.00029 20.2 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 CCM02173.1 - 0.0012 18.1 0.0 0.0044 16.2 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.21 CCM02173.1 - 0.0035 17.7 0.0 0.007 16.7 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3954 PF13128.1 CCM02173.1 - 0.049 13.0 0.1 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) Ribosomal_S13_N PF08069.7 CCM02174.1 - 1.7e-29 101.4 0.1 3e-29 100.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CCM02174.1 - 7.8e-20 70.4 0.1 1.9e-19 69.1 0.1 1.7 1 1 1 2 2 2 1 Ribosomal protein S15 Pox_VLTF3 PF04947.9 CCM02174.1 - 0.031 13.8 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Ribosomal_S6e PF01092.14 CCM02175.1 - 4.4e-62 207.3 0.1 7.8e-62 206.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e DUF2413 PF10310.4 CCM02176.1 - 8.1e-78 262.2 1.2 2.9e-77 260.3 0.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) Chromo PF00385.19 CCM02177.1 - 4.1e-06 26.3 2.8 4.9e-06 26.1 0.5 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tim17 PF02466.14 CCM02178.1 - 1.9e-21 76.4 0.7 2.8e-21 75.8 0.2 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Ras PF00071.17 CCM02179.1 - 1.1e-42 145.1 0.1 5.2e-36 123.4 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCM02179.1 - 1.9e-12 47.7 0.0 5.2e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CCM02179.1 - 0.0029 17.0 0.0 0.0053 16.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 CCM02179.1 - 0.092 12.3 0.1 0.21 11.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 CCM02179.1 - 0.11 11.7 0.1 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCM02179.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Yippee-Mis18 PF03226.9 CCM02181.1 - 3.7e-22 78.1 0.2 4.1e-22 78.0 0.2 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 CCM02181.1 - 0.012 15.5 1.2 0.86 9.5 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Peptidase_C48 PF02902.14 CCM02182.1 - 6.6e-25 87.9 1.0 1.2e-24 87.1 0.7 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SNARE PF05739.14 CCM02183.1 - 4.1e-08 32.7 0.5 5.2e-08 32.4 0.4 1.1 1 0 0 1 1 1 1 SNARE domain Sgf11 PF08209.6 CCM02185.1 - 2e-09 36.5 0.6 2e-09 36.5 0.4 1.8 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) CBS PF00571.23 CCM02186.1 - 4.4e-37 125.6 10.2 3.9e-09 36.1 0.1 5.4 5 0 0 5 5 5 5 CBS domain PB1 PF00564.19 CCM02186.1 - 1.9e-08 33.8 0.0 6.5e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 PB1 domain DUF2992 PF11208.3 CCM02186.1 - 0.65 9.9 4.6 0.69 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) DUF1282 PF06930.7 CCM02187.1 - 0.018 14.6 2.1 0.025 14.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Glyco_transf_64 PF09258.5 CCM02187.1 - 0.03 13.4 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain DUF4366 PF14283.1 CCM02187.1 - 0.078 12.3 0.5 0.1 11.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) UPF0121 PF03661.8 CCM02188.1 - 1.3e-24 86.7 1.1 1.6e-24 86.4 0.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DEAD PF00270.24 CCM02189.1 - 1.2e-30 106.2 0.0 4.4e-29 101.1 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM02189.1 - 5.6e-21 74.1 0.0 1.1e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCM02189.1 - 2.4e-20 71.8 0.3 5.1e-20 70.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) PTH2 PF01981.11 CCM02190.1 - 1.4e-45 153.7 0.0 1.9e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PhzC-PhzF PF02567.11 CCM02190.1 - 0.15 11.2 0.3 0.4 9.8 0.2 1.6 1 1 0 1 1 1 0 Phenazine biosynthesis-like protein Mpv17_PMP22 PF04117.7 CCM02191.1 - 8.8e-23 79.7 0.1 1.5e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-Tim10_DDP PF02953.10 CCM02192.1 - 1.4e-14 53.0 0.1 1.3e-13 49.9 0.1 1.9 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Bclx_interact PF08945.5 CCM02192.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Bcl-x interacting, BH3 domain Beta_elim_lyase PF01212.16 CCM02193.1 - 2.4e-63 214.0 0.0 3.1e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCM02193.1 - 0.021 13.8 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CCM02193.1 - 0.037 12.3 0.0 0.053 11.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Urb2 PF10441.4 CCM02194.1 - 1.7e-29 103.0 0.6 4.2e-29 101.7 0.1 2.0 2 0 0 2 2 2 1 Urb2/Npa2 family COX4_pro_2 PF07835.7 CCM02195.1 - 0.19 11.7 1.0 0.37 10.8 0.7 1.4 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV RWD PF05773.17 CCM02196.1 - 1e-17 64.0 0.0 2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 CCM02196.1 - 1.1e-14 54.0 40.0 6e-09 35.6 2.0 4.2 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 CCM02196.1 - 8.2e-05 22.3 9.9 8.2e-05 22.3 6.9 4.9 3 2 2 5 5 5 1 Ring finger domain zf-RING_5 PF14634.1 CCM02196.1 - 0.00048 19.7 7.8 0.00048 19.7 5.4 4.6 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCM02196.1 - 0.0065 16.0 9.3 0.0065 16.0 6.5 5.2 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCM02196.1 - 0.019 15.0 11.2 0.019 15.0 7.8 5.5 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCM02196.1 - 5.3 6.8 19.6 0.024 14.3 4.1 3.0 2 0 0 2 2 2 0 RING-type zinc-finger KH_1 PF00013.24 CCM02197.1 - 1.4e-34 117.5 0.1 1.7e-08 33.9 0.0 7.1 7 0 0 7 7 7 4 KH domain KH_3 PF13014.1 CCM02197.1 - 6.8e-25 86.2 3.5 7e-06 25.5 0.1 6.3 6 0 0 6 6 6 4 KH domain Rhodanese PF00581.15 CCM02198.1 - 1.1e-14 54.7 0.0 2.3e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain Multi_ubiq PF14452.1 CCM02198.1 - 0.0011 18.9 0.0 0.0029 17.5 0.0 1.7 2 0 0 2 2 2 1 Multiubiquitin Ctr PF04145.10 CCM02199.1 - 1.8e-27 96.1 0.9 2.3e-27 95.8 0.7 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF2093 PF09866.4 CCM02200.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) Kinesin PF00225.18 CCM02202.1 - 1.5e-94 316.4 0.0 2.2e-94 315.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Pox_A_type_inc PF04508.7 CCM02202.1 - 0.11 12.3 3.8 0.29 11.0 2.7 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DivIC PF04977.10 CCM02202.1 - 0.35 10.3 2.3 0.68 9.4 1.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Rhodanese PF00581.15 CCM02203.1 - 2.6e-16 59.9 0.0 2.4e-09 37.5 0.0 3.2 3 0 0 3 3 3 3 Rhodanese-like domain V-ATPase_C PF03223.10 CCM02204.1 - 3.2e-115 385.0 0.7 3.6e-115 384.8 0.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Frataxin_Cyay PF01491.11 CCM02205.1 - 2.4e-26 91.6 0.0 6.7e-17 61.2 0.0 2.0 2 0 0 2 2 2 2 Frataxin-like domain WD40 PF00400.27 CCM02207.1 - 5.4e-19 67.2 12.3 0.00018 21.2 0.1 7.6 8 0 0 8 8 8 4 WD domain, G-beta repeat eIF2A PF08662.6 CCM02207.1 - 0.063 12.9 0.0 18 4.9 0.0 3.2 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A Bromodomain PF00439.20 CCM02208.1 - 2.8e-40 136.1 0.0 1e-21 76.6 0.0 2.7 2 0 0 2 2 2 2 Bromodomain Spt5_N PF11942.3 CCM02208.1 - 0.058 14.0 8.2 0.2 12.2 5.7 2.0 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal FlaC_arch PF05377.6 CCM02208.1 - 0.15 12.0 0.7 11 6.0 0.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 CCM02208.1 - 0.19 11.5 1.0 0.53 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) G-patch PF01585.18 CCM02209.1 - 1.2e-09 37.8 0.1 2.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 CCM02209.1 - 1.8e-06 27.8 5.6 3.3e-06 27.0 3.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM02209.1 - 1.4e-05 25.0 0.9 2.5e-05 24.3 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Topoisom_I_N PF02919.10 CCM02209.1 - 0.001 18.4 0.3 0.0016 17.7 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment G-patch_2 PF12656.2 CCM02209.1 - 0.0065 16.3 0.1 0.0065 16.3 0.0 2.8 3 0 0 3 3 3 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 CCM02209.1 - 0.036 14.1 1.8 0.061 13.4 1.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RNase_H2-Ydr279 PF09468.5 CCM02209.1 - 0.082 12.0 5.6 0.15 11.2 3.9 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) zf-DBF PF07535.7 CCM02209.1 - 0.19 11.3 2.7 0.41 10.3 1.9 1.4 1 0 0 1 1 1 0 DBF zinc finger DUF4407 PF14362.1 CCM02209.1 - 10 5.0 6.5 15 4.4 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Helicase_C PF00271.26 CCM02210.1 - 2.3e-19 69.0 0.0 2.1e-18 65.9 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCM02210.1 - 1.3e-18 67.0 0.0 2.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCM02210.1 - 2.5e-17 63.3 0.0 5.9e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 CCM02211.1 - 4.5e-05 23.1 3.3 7.7e-05 22.4 2.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCM02211.1 - 0.0022 17.9 3.4 0.0041 17.1 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCM02211.1 - 0.067 12.8 2.4 0.12 12.0 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCM02211.1 - 0.13 11.9 0.7 0.23 11.1 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glucosamine_iso PF01182.15 CCM02212.1 - 6.9e-67 225.0 0.0 8.3e-67 224.7 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PXA PF02194.10 CCM02213.1 - 1.5e-30 106.1 0.0 2.4e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 PXA domain RRM_6 PF14259.1 CCM02215.1 - 8.6e-10 38.4 0.0 9.3e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 CCM02215.1 - 1.2e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 CCM02215.1 - 3.2e-05 23.4 5.8 5.9e-05 22.6 4.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 CCM02215.1 - 0.02 14.7 0.5 0.23 11.3 0.0 2.5 3 0 0 3 3 3 0 RNA binding motif Melibiase PF02065.13 CCM02216.1 - 1.1e-34 119.8 0.0 6.6e-18 64.5 0.0 2.1 2 0 0 2 2 2 2 Melibiase p450 PF00067.17 CCM02218.1 - 1.8e-63 214.6 0.0 2.3e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M48 PF01435.13 CCM02219.1 - 1.3e-17 64.1 0.0 2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 CCM02219.1 - 0.026 14.5 0.1 0.063 13.3 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily DUF955 PF06114.8 CCM02219.1 - 0.11 12.2 0.4 0.44 10.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF1192 PF06698.6 CCM02219.1 - 0.19 11.5 1.6 0.49 10.2 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) COX5B PF01215.14 CCM02220.1 - 1.1e-40 138.4 0.0 1.3e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb A2L_zn_ribbon PF08792.5 CCM02220.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain Na_Ca_ex PF01699.19 CCM02221.1 - 3.9e-22 78.3 25.6 4.8e-18 65.0 7.5 2.7 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Cyanate_lyase PF02560.9 CCM02222.1 - 6.7e-35 118.4 0.1 1.7e-34 117.1 0.0 1.7 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 CCM02222.1 - 0.057 13.6 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1479 PF07350.7 CCM02223.1 - 2.1e-115 385.5 0.1 4.9e-115 384.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1479) PhaP_Bmeg PF09602.5 CCM02223.1 - 0.045 13.5 0.4 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Tubulin PF00091.20 CCM02224.1 - 1.4e-62 211.3 0.0 2.1e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCM02224.1 - 3.8e-40 136.8 0.0 5.7e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCM02224.1 - 4.7e-06 26.6 0.0 1.2e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Transketolase_N PF00456.16 CCM02227.1 - 4.6e-18 65.1 0.5 4.9e-17 61.7 0.3 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 CCM02227.1 - 3.4e-08 33.4 0.0 7.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 CCM02227.1 - 4.2e-06 26.3 0.4 8.2e-06 25.4 0.1 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 CCM02227.1 - 0.0044 16.6 0.0 0.017 14.6 0.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 CCM02227.1 - 0.0045 15.7 0.0 0.0071 15.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4478 PF14793.1 CCM02227.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) VID27 PF08553.5 CCM02228.1 - 0.1 10.7 0.9 0.14 10.3 0.6 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Sigma70_ner PF04546.8 CCM02228.1 - 0.85 9.1 6.1 1.3 8.5 4.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4112 PF13430.1 CCM02229.1 - 2.5e-20 72.3 0.2 3e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) MFS_1 PF07690.11 CCM02233.1 - 3.9e-26 91.6 7.8 4.5e-26 91.3 5.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Ceramidase PF05875.7 CCM02233.1 - 0.074 12.1 6.6 0.11 11.5 4.6 1.2 1 0 0 1 1 1 0 Ceramidase ZYG-11_interact PF05884.7 CCM02233.1 - 0.083 11.9 0.2 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF1616 PF07760.6 CCM02233.1 - 0.5 9.4 5.5 0.72 8.9 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) PUCC PF03209.10 CCM02233.1 - 0.55 8.8 7.7 1.1 7.9 5.3 1.5 1 1 0 1 1 1 0 PUCC protein DUF2207 PF09972.4 CCM02233.1 - 1.6 7.2 4.3 2.9 6.3 3.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Use1 PF09753.4 CCM02233.1 - 4.5 6.6 6.1 6.9 6.0 4.3 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 MFS_1 PF07690.11 CCM02234.1 - 1.2e-29 103.1 27.4 2.7e-27 95.4 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.4 CCM02234.1 - 1.2 7.6 4.6 4.5 5.7 3.2 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Use1 PF09753.4 CCM02234.1 - 8.5 5.7 6.3 16 4.8 4.4 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 Asp PF00026.18 CCM02235.1 - 3e-75 253.4 11.3 3.6e-75 253.1 7.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM02235.1 - 2.7e-05 24.1 2.0 9.2e-05 22.4 1.4 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCM02235.1 - 0.0077 15.7 1.7 0.019 14.5 0.1 2.4 3 1 1 4 4 4 1 Xylanase inhibitor C-terminal Cu_bind_like PF02298.12 CCM02236.1 - 0.0016 18.2 1.0 0.017 14.9 0.7 2.2 1 1 0 1 1 1 1 Plastocyanin-like domain A_deaminase PF00962.17 CCM02237.1 - 3.7e-50 170.7 0.0 6.4e-50 169.9 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase p450 PF00067.17 CCM02239.1 - 9.1e-64 215.6 0.0 1.3e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GST_C_3 PF14497.1 CCM02240.1 - 0.012 16.0 0.0 0.046 14.2 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 CCM02240.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF2450 PF10475.4 CCM02241.1 - 0.0085 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Mito_carr PF00153.22 CCM02242.1 - 2.9e-32 110.2 7.0 4.4e-19 67.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Trp_halogenase PF04820.9 CCM02243.1 - 4e-13 48.7 0.0 6.1e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.14 CCM02243.1 - 0.00021 20.4 0.0 0.00044 19.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCM02243.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase p450 PF00067.17 CCM02244.1 - 5.5e-61 206.5 0.0 5.9e-59 199.8 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 CCM02246.1 - 5e-42 143.8 66.8 5e-42 143.8 46.3 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 CCM02246.1 - 0.0025 17.3 2.1 0.0025 17.3 1.5 4.4 4 2 1 5 5 5 2 Ion channel regulatory protein UNC-93 ketoacyl-synt PF00109.21 CCM02247.1 - 3.6e-51 174.1 0.2 9.5e-51 172.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CCM02247.1 - 1.1e-46 159.6 0.0 1.8e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 CCM02247.1 - 7.1e-32 110.7 0.0 1.9e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 CCM02247.1 - 9.4e-32 109.8 0.0 1.6e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 CCM02247.1 - 3.4e-30 105.0 3.4 4.2e-28 98.2 0.3 2.6 2 0 0 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.17 CCM02247.1 - 4.2e-29 100.8 0.0 1.2e-28 99.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 CCM02247.1 - 9.4e-28 97.2 5.6 6.3e-25 88.0 0.8 3.2 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.16 CCM02247.1 - 2.8e-07 30.2 0.0 1e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CCM02247.1 - 1.1e-05 25.5 0.3 0.00017 21.7 0.1 3.0 3 0 0 3 3 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 CCM02247.1 - 0.00063 18.5 0.0 0.0044 15.7 0.0 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family ACP_syn_III PF08545.5 CCM02247.1 - 0.021 14.4 0.7 0.057 13.0 0.5 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 CCM02247.1 - 0.024 13.5 0.1 0.053 12.5 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 CCM02247.1 - 0.48 9.2 0.1 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 CCM02249.1 - 5.2e-12 45.9 0.3 7.4e-12 45.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM02249.1 - 0.017 14.7 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 KR domain AAA PF00004.24 CCM02250.1 - 7.1e-13 48.8 0.0 1.4e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCM02250.1 - 5.2e-10 39.6 0.0 5.8e-09 36.2 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 CCM02250.1 - 8e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 CCM02250.1 - 9.1e-07 29.0 0.0 3.3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM02250.1 - 0.0002 21.0 0.0 0.0008 19.1 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CCM02250.1 - 0.0005 19.1 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 CCM02250.1 - 0.0069 15.9 0.1 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCM02250.1 - 0.011 15.3 0.0 0.045 13.4 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 CCM02250.1 - 0.094 13.5 0.0 0.34 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CCM02250.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 CCM02250.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.8 CCM02250.1 - 0.21 10.2 0.0 0.39 9.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus PIF1 PF05970.9 CCM02250.1 - 0.34 9.8 0.0 0.52 9.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Pol_alpha_B_N PF08418.5 CCM02250.1 - 1.7 8.1 18.1 3.7 7.0 12.4 1.7 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DHBP_synthase PF00926.14 CCM02251.1 - 1.3e-76 256.1 0.0 1.5e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Homeobox PF00046.24 CCM02253.1 - 1.2e-15 56.8 4.6 2.2e-15 56.0 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCM02253.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF2804 PF10974.3 CCM02253.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) Methyltransf_16 PF10294.4 CCM02254.1 - 1.3e-16 60.5 0.0 2.1e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCM02254.1 - 7e-07 29.8 0.0 1.8e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM02254.1 - 0.00029 20.4 0.0 0.00085 18.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM02254.1 - 0.00053 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM02254.1 - 0.00074 19.9 0.0 0.0032 17.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CCM02254.1 - 0.004 16.3 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 CCM02254.1 - 0.027 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CCM02254.1 - 0.048 13.0 0.0 0.083 12.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 CCM02254.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 CCM02254.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF4268 PF14088.1 CCM02255.1 - 0.046 13.3 0.1 0.057 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Ribosomal_L2_C PF03947.13 CCM02256.1 - 6.7e-51 171.4 0.4 1.1e-50 170.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCM02256.1 - 3.5e-25 87.7 0.1 6.8e-25 86.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TIP49 PF06068.8 CCM02257.1 - 1.9e-177 589.9 2.4 2.5e-177 589.5 1.6 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CCM02257.1 - 3.1e-09 37.1 1.2 1.2e-05 25.5 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCM02257.1 - 2.2e-06 26.9 1.7 0.0019 17.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 CCM02257.1 - 0.00015 20.7 0.3 0.00026 19.9 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.1 CCM02257.1 - 0.00072 19.0 0.1 0.0017 17.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCM02257.1 - 0.0011 19.0 0.4 0.44 10.6 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CCM02257.1 - 0.0015 18.5 0.0 0.014 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 CCM02257.1 - 0.004 16.3 6.6 0.067 12.3 0.4 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCM02257.1 - 0.067 12.9 3.6 6.8 6.4 0.0 3.6 3 2 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCM02257.1 - 0.13 12.0 0.8 1.7 8.4 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain DUF2271 PF10029.4 CCM02258.1 - 0.039 13.4 0.3 0.058 12.8 0.2 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Ribosomal_L21e PF01157.13 CCM02259.1 - 1.4e-38 130.7 4.1 2.8e-38 129.6 2.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e RNA_replicase_B PF03431.8 CCM02259.1 - 0.009 14.2 0.3 0.01 14.0 0.2 1.0 1 0 0 1 1 1 1 RNA replicase, beta-chain Surface_Ag_2 PF01617.12 CCM02259.1 - 0.098 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Surface antigen Ribosomal_S4 PF00163.14 CCM02260.1 - 4.2e-26 91.1 0.4 7.9e-26 90.2 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCM02260.1 - 2e-13 49.5 1.3 2e-13 49.5 0.9 2.8 3 0 0 3 3 3 1 S4 domain Aldo_ket_red PF00248.16 CCM02261.1 - 2.2e-71 240.0 0.0 2.8e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3140 PF11338.3 CCM02262.1 - 7e-21 74.1 0.5 7e-21 74.1 0.4 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3140) Chitin_synth_2 PF03142.10 CCM02263.1 - 5.4e-278 922.6 0.1 7.3e-278 922.2 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CCM02263.1 - 2.2e-14 53.6 0.2 5e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCM02263.1 - 1e-12 48.3 0.0 5.4e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CCM02263.1 - 0.0007 19.3 0.3 0.003 17.3 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 CCM02263.1 - 0.0066 15.7 0.0 0.028 13.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CCM02263.1 - 0.0075 15.9 0.0 0.043 13.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 GspL_C PF12693.2 CCM02263.1 - 1.4 8.6 5.4 14 5.4 4.2 2.2 3 0 0 3 3 3 0 GspL periplasmic domain Raptor_N PF14538.1 CCM02264.1 - 5.7e-61 204.8 0.0 1.1e-60 203.9 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain zf-C2H2_4 PF13894.1 CCM02264.1 - 2e-10 40.2 4.4 5e-05 23.3 0.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM02264.1 - 4.1e-09 36.2 4.2 0.00062 19.9 0.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type WD40 PF00400.27 CCM02264.1 - 6.2e-09 35.4 13.4 7e-06 25.7 0.3 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat HEAT PF02985.17 CCM02264.1 - 1.4e-06 27.8 0.5 0.00015 21.5 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CCM02264.1 - 2.8e-05 24.3 1.2 0.00028 21.0 0.0 3.2 4 1 0 4 4 3 1 HEAT repeats zf-C2H2_jaz PF12171.3 CCM02264.1 - 6.9e-05 22.8 1.8 0.39 10.9 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCM02264.1 - 0.0024 17.7 1.6 0.0033 17.2 0.3 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger HEAT_EZ PF13513.1 CCM02264.1 - 0.0048 17.3 2.8 0.0075 16.7 0.0 3.0 3 0 0 3 3 2 1 HEAT-like repeat Arm PF00514.18 CCM02264.1 - 0.038 13.8 0.1 1.7 8.5 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat zf-H2C2_2 PF13465.1 CCM02264.1 - 2.2 8.7 10.8 0.3 11.4 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double domain PfkB PF00294.19 CCM02265.1 - 8.1e-64 215.6 0.2 9.7e-64 215.3 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase 7kD_coat PF02495.12 CCM02265.1 - 0.055 12.9 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 7kD viral coat protein Ribosomal_S19 PF00203.16 CCM02266.1 - 9.5e-23 79.6 0.0 1.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DUF2363 PF10155.4 CCM02268.1 - 0.00031 20.6 0.0 0.0008 19.3 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) TFIIF_alpha PF05793.7 CCM02271.1 - 1.1 7.5 8.8 1.4 7.2 6.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) STE3 PF02076.10 CCM02272.1 - 4.2e-100 334.4 14.9 5.1e-100 334.2 10.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 CCM02274.1 - 8.7e-102 340.0 22.7 1e-101 339.7 15.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 CCM02275.1 - 3.4e-91 305.2 22.4 4.1e-91 304.9 15.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 CCM02276.1 - 1.2e-63 214.8 6.9 1.4e-63 214.5 4.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor ABC2_membrane_4 PF12730.2 CCM02276.1 - 0.56 9.3 7.3 2.3 7.3 0.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Pheromone PF08015.6 CCM02277.1 - 4.4e-05 24.2 0.7 0.042 14.6 0.1 2.4 2 1 0 2 2 2 2 Fungal mating-type pheromone STE3 PF02076.10 CCM02279.1 - 1.3e-30 106.4 10.5 1.7e-30 106.0 7.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 CCM02280.1 - 1.8e-86 289.7 24.4 2.2e-86 289.4 16.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor SGL PF08450.7 CCM02281.1 - 2e-25 89.5 0.0 3.4e-25 88.8 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CCM02281.1 - 0.00014 21.8 0.0 0.0005 20.0 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 CCM02281.1 - 0.015 15.3 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 Arylesterase NHL PF01436.16 CCM02281.1 - 0.059 13.3 0.0 14 5.8 0.0 3.0 2 0 0 2 2 2 0 NHL repeat Myb_DNA-binding PF00249.26 CCM02282.1 - 1.4e-15 57.1 0.3 1.3e-08 34.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCM02282.1 - 5.9e-11 42.2 0.1 7.3e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.5 CCM02282.1 - 0.012 15.3 0.2 0.83 9.4 0.0 2.3 2 0 0 2 2 2 0 SLIDE PCI PF01399.22 CCM02283.1 - 9.6e-10 38.7 0.0 2.4e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain Prefoldin PF02996.12 CCM02284.1 - 1.6e-27 95.5 0.3 5.2e-26 90.6 0.2 2.2 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CCM02284.1 - 0.0023 17.6 0.9 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit Syntaxin-6_N PF09177.6 CCM02284.1 - 0.11 12.9 0.7 5 7.5 0.1 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HrpB7 PF09486.5 CCM02284.1 - 0.87 9.5 6.4 0.47 10.3 0.3 2.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) SNF2_N PF00176.18 CCM02285.1 - 1.3e-43 148.9 0.0 7.4e-43 146.4 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.1 CCM02285.1 - 7.1e-07 29.1 3.4 1.9e-06 27.7 2.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCM02285.1 - 2.9e-06 26.8 1.7 6.5e-06 25.7 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCM02285.1 - 1.4e-05 24.8 4.3 3.3e-05 23.6 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCM02285.1 - 6.1e-05 22.6 5.5 0.00013 21.5 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCM02285.1 - 0.00015 21.3 4.4 0.00032 20.3 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 CCM02285.1 - 0.0015 18.0 2.2 0.0038 16.7 1.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 CCM02285.1 - 0.053 13.2 1.0 0.14 11.9 0.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Di19 PF05605.7 CCM02286.1 - 0.7 10.0 6.4 7.6 6.7 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RdRP PF05183.7 CCM02288.1 - 8.2e-105 351.6 0.0 1.2e-104 351.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase CIA30 PF08547.7 CCM02288.1 - 8.4e-20 71.2 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Ras PF00071.17 CCM02289.1 - 1.2e-56 190.5 0.1 1.4e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM02289.1 - 6.4e-18 65.3 0.0 9.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM02289.1 - 1.2e-07 31.1 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM02289.1 - 1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CCM02289.1 - 0.0026 17.0 0.1 0.0082 15.4 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CCM02289.1 - 0.0091 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ser_hydrolase PF06821.8 CCM02289.1 - 0.065 12.8 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase IstB_IS21 PF01695.12 CCM02289.1 - 0.16 11.3 0.4 0.94 8.8 0.0 2.3 2 1 1 3 3 3 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 CCM02289.1 - 0.32 10.5 1.5 2.9 7.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IMS PF00817.15 CCM02291.1 - 2.4e-40 137.7 0.0 5.7e-40 136.5 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family Pyr_redox_2 PF07992.9 CCM02291.1 - 1.1e-27 97.2 0.9 1.9e-27 96.4 0.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 CCM02291.1 - 2.5e-16 59.0 0.1 6.3e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain IMS_C PF11799.3 CCM02291.1 - 3.1e-12 46.5 0.0 1.1e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Pyr_redox_3 PF13738.1 CCM02291.1 - 2.7e-08 34.0 0.4 3.3e-06 27.3 0.0 2.9 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM02291.1 - 7.6e-07 29.4 6.2 2.6e-06 27.7 0.3 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 CCM02291.1 - 3.4e-05 24.0 0.0 9.6e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 CCM02291.1 - 0.00085 18.3 0.1 0.9 8.3 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) SAD_SRA PF02182.12 CCM02292.1 - 8.2e-47 158.3 0.0 1.1e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 SAD/SRA domain F-box PF00646.28 CCM02294.1 - 0.061 12.9 0.4 0.16 11.6 0.3 1.7 1 0 0 1 1 1 0 F-box domain Na_sulph_symp PF00939.14 CCM02295.1 - 3.6e-30 105.2 21.9 4.6e-30 104.9 15.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCM02295.1 - 2.1e-17 62.7 24.2 2.3e-13 49.4 4.3 2.0 1 1 1 2 2 2 2 Citrate transporter ATP-synt_8 PF00895.15 CCM02295.1 - 0.048 13.8 0.1 0.048 13.8 0.0 3.9 5 0 0 5 5 5 0 ATP synthase protein 8 BetaGal_dom4_5 PF13364.1 CCM02296.1 - 7.7e-44 148.5 6.2 2.5e-22 79.2 0.4 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 CCM02296.1 - 2e-33 115.2 1.3 4.8e-33 114.0 0.9 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 CCM02296.1 - 1.7e-19 69.0 1.8 3.4e-19 68.0 0.2 2.4 4 0 0 4 4 4 1 Beta-galactosidase, domain 3 BTB PF00651.26 CCM02297.1 - 0.0017 18.2 0.0 0.18 11.8 0.0 2.9 2 1 0 2 2 2 2 BTB/POZ domain Glyco_hydro_15 PF00723.16 CCM02298.1 - 2.6e-51 174.6 0.0 9.1e-51 172.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Complex1_51K PF01512.12 CCM02299.1 - 3.8e-48 163.0 0.0 5.6e-48 162.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CCM02299.1 - 2.7e-21 74.4 3.8 2.8e-21 74.3 0.5 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CCM02299.1 - 5.4e-09 35.8 0.0 2.2e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 SLBB domain DUF780 PF05611.6 CCM02299.1 - 0.043 14.5 0.8 0.11 13.1 0.6 1.7 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) Glyco_hydro_2 PF00703.16 CCM02300.1 - 4.4e-06 27.1 0.0 1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 CCM02300.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 CCM02300.1 - 0.031 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Aldedh PF00171.17 CCM02302.1 - 1e-77 261.4 0.0 2.5e-56 190.9 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 CCM02302.1 - 0.0025 16.6 0.0 0.0074 15.0 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) COesterase PF00135.23 CCM02303.1 - 3.5e-94 316.4 3.2 1.3e-93 314.5 2.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM02303.1 - 2.3e-11 43.6 0.1 1.5e-10 40.9 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM02303.1 - 0.0016 17.6 0.1 0.003 16.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family HET PF06985.6 CCM02305.1 - 4e-14 52.9 2.2 2.9e-12 46.9 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Peptidase_M16 PF00675.15 CCM02306.1 - 9.3e-27 93.6 0.0 1.8e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCM02306.1 - 2.2e-22 79.6 0.0 5.2e-10 39.3 0.0 3.6 4 0 0 4 4 4 2 Peptidase M16 inactive domain RicinB_lectin_2 PF14200.1 CCM02307.1 - 0.022 15.1 0.1 0.022 15.1 0.0 2.6 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like DUF3005 PF11448.3 CCM02307.1 - 0.032 13.8 0.1 0.068 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) Phage_Mu_Gam PF07352.7 CCM02307.1 - 0.17 11.4 6.6 2.5 7.5 1.4 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Ribosomal_60s PF00428.14 CCM02309.1 - 3.8e-27 94.4 11.9 5e-27 94.1 8.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Kelch_5 PF13854.1 CCM02310.1 - 1.5e-19 69.4 2.9 2.1e-06 27.5 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 CCM02310.1 - 3e-19 68.5 11.6 2.2e-07 30.5 0.3 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CCM02310.1 - 9e-16 57.5 20.2 2.6e-09 37.0 0.1 7.8 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 CCM02310.1 - 2.6e-06 26.8 0.2 2.6e-06 26.8 0.2 5.2 6 0 0 6 6 6 1 Kelch motif Kelch_6 PF13964.1 CCM02310.1 - 9e-06 25.6 10.4 0.069 13.3 0.1 6.8 7 0 0 7 7 7 1 Kelch motif Kelch_2 PF07646.10 CCM02310.1 - 0.00024 20.7 6.6 0.00044 19.8 0.4 3.6 4 0 0 4 4 4 1 Kelch motif Prefoldin_2 PF01920.15 CCM02311.1 - 1.7e-21 75.9 3.4 2.1e-21 75.6 2.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit TMF_DNA_bd PF12329.3 CCM02311.1 - 0.0023 17.7 5.0 0.053 13.3 0.1 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 CCM02311.1 - 0.0042 16.7 4.0 0.37 10.4 0.1 2.1 1 1 1 2 2 2 2 Prefoldin subunit FTA4 PF13093.1 CCM02311.1 - 0.01 15.2 2.6 0.013 14.9 1.8 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_23 PF13476.1 CCM02311.1 - 0.033 14.5 4.0 0.043 14.1 2.8 1.1 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 CCM02311.1 - 0.035 14.2 6.0 0.12 12.5 1.5 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pneumo_phosprot PF02478.11 CCM02311.1 - 0.041 13.4 0.8 0.041 13.4 0.5 1.7 2 1 0 2 2 2 0 Pneumovirus phosphoprotein TMF_TATA_bd PF12325.3 CCM02311.1 - 0.046 13.4 4.9 0.85 9.3 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sed5p PF11416.3 CCM02311.1 - 0.099 12.0 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Integral membrane protein Sed5p Laminin_II PF06009.7 CCM02311.1 - 0.13 12.0 0.9 4.7 6.9 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II Katanin_con80 PF13925.1 CCM02311.1 - 0.15 11.8 1.1 2.8 7.6 0.1 2.0 2 0 0 2 2 2 0 con80 domain of Katanin Snapin_Pallidin PF14712.1 CCM02311.1 - 0.21 11.9 2.5 7.2 6.9 0.1 2.7 2 1 1 3 3 3 0 Snapin/Pallidin TBPIP PF07106.8 CCM02311.1 - 0.21 11.1 4.5 2.4 7.6 0.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4164 PF13747.1 CCM02311.1 - 0.24 11.5 4.5 0.6 10.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF972 PF06156.8 CCM02311.1 - 0.27 11.6 3.5 10 6.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CCM02311.1 - 0.27 10.7 2.9 4.6 6.7 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator Sipho_Gp157 PF05565.6 CCM02311.1 - 0.28 10.7 8.2 0.49 9.9 0.2 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 Spc24 PF08286.6 CCM02311.1 - 0.29 10.8 6.2 4.1 7.1 0.1 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 SPT2 PF08243.6 CCM02311.1 - 0.35 11.2 5.4 6.6 7.0 0.0 2.2 2 0 0 2 2 2 0 SPT2 chromatin protein DUF16 PF01519.11 CCM02311.1 - 0.44 10.7 2.8 0.65 10.2 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4200 PF13863.1 CCM02311.1 - 0.58 10.1 8.7 1.9 8.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ApoL PF05461.6 CCM02311.1 - 0.65 9.1 3.5 0.54 9.4 1.5 1.4 1 1 0 1 1 1 0 Apolipoprotein L FlaC_arch PF05377.6 CCM02311.1 - 0.83 9.5 5.9 2.9 7.8 0.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 CCM02311.1 - 0.89 9.1 11.5 10 5.6 8.1 1.9 1 1 0 1 1 1 0 IncA protein YvrJ PF12841.2 CCM02311.1 - 1.1 8.5 4.0 8.3 5.7 0.4 2.8 2 1 1 3 3 3 0 YvrJ protein family DUF4140 PF13600.1 CCM02311.1 - 1.3 9.4 4.1 5.3 7.5 0.6 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.13 CCM02311.1 - 1.9 8.2 6.2 12 5.6 0.7 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Syntaxin PF00804.20 CCM02311.1 - 2 8.5 7.8 1.4 9.0 2.9 2.0 1 1 1 2 2 2 0 Syntaxin DUF342 PF03961.8 CCM02311.1 - 3.3 6.0 5.0 4.3 5.6 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) NYD-SP28 PF14772.1 CCM02311.1 - 5.7 7.0 10.3 6 7.0 2.0 2.1 2 0 0 2 2 2 0 Sperm tail bZIP_1 PF00170.16 CCM02311.1 - 9.6 6.2 8.5 18 5.3 0.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF2570 PF10828.3 CCM02313.1 - 0.37 10.4 3.1 0.49 10.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) ATP-synt_B PF00430.13 CCM02313.1 - 1.2 8.9 12.8 1.7 8.4 8.9 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2058 PF09831.4 CCM02313.1 - 9.1 6.1 9.8 15 5.4 6.4 1.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) RasGAP PF00616.14 CCM02314.1 - 2.2e-35 122.1 0.5 1.1e-33 116.5 0.0 2.9 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase MOR2-PAG1_C PF14225.1 CCM02314.1 - 1.5e-06 28.1 0.1 5e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal CRAL_TRIO_2 PF13716.1 CCM02314.1 - 6.5e-05 22.8 0.1 0.00027 20.8 0.1 2.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Syntaxin PF00804.20 CCM02314.1 - 0.13 12.4 0.1 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 Syntaxin Abhydrolase_2 PF02230.11 CCM02315.1 - 5.2e-41 140.4 0.0 1.3e-40 139.2 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CCM02315.1 - 1.2e-09 38.1 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM02315.1 - 4.9e-06 26.5 0.1 0.00018 21.4 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 CCM02315.1 - 0.00017 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 CCM02315.1 - 0.00038 19.8 0.0 0.00052 19.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 CCM02315.1 - 0.00095 18.6 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 CCM02315.1 - 0.0015 17.7 0.0 0.49 9.5 0.0 2.1 1 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CCM02315.1 - 0.0037 16.8 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 CCM02315.1 - 0.034 13.7 0.3 0.23 10.9 0.1 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.17 CCM02315.1 - 0.074 12.7 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Cutinase Isochorismatase PF00857.15 CCM02317.1 - 1.6e-37 129.1 0.0 2e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family RRP7 PF12923.2 CCM02318.1 - 3.9e-35 120.7 3.7 3.9e-35 120.7 2.6 1.5 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 CCM02318.1 - 0.0086 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM02318.1 - 0.022 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Vps36_ESCRT-II PF11605.3 CCM02319.1 - 0.021 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 CCM02319.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 GRAM domain WWbp PF10349.4 CCM02319.1 - 0.088 13.7 0.5 0.2 12.5 0.3 1.6 1 1 0 1 1 1 0 WW-domain ligand protein Grp1_Fun34_YaaH PF01184.14 CCM02320.1 - 1.5e-48 164.8 9.7 1.8e-48 164.6 6.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 CCM02321.1 - 1.4e-46 158.4 10.8 2.2e-46 157.8 7.5 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pkinase PF00069.20 CCM02322.1 - 4.6e-40 137.4 0.0 2.9e-24 85.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02322.1 - 2.4e-12 46.4 0.0 1e-09 37.8 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CCM02322.1 - 0.00016 21.4 0.3 0.00085 19.1 0.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCM02322.1 - 0.085 11.7 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like UCH PF00443.24 CCM02323.1 - 5.7e-34 117.4 0.0 7.7e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM02323.1 - 7.5e-09 35.4 0.0 2.4e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1992 PF09350.5 CCM02325.1 - 7.9e-19 67.2 0.3 2.1e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Aldedh PF00171.17 CCM02326.1 - 8.9e-104 347.3 0.0 1.2e-103 346.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cellulase PF00150.13 CCM02327.1 - 6.3e-48 163.3 0.3 8.3e-48 162.9 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 CCM02327.1 - 9.1e-14 50.8 9.0 3.9e-13 48.7 6.3 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Phytochelatin_C PF09328.5 CCM02327.1 - 0.038 13.4 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) GATase_5 PF13507.1 CCM02327.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain BTB PF00651.26 CCM02328.1 - 8.4e-14 51.5 0.0 3.1e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Stc1 PF12898.2 CCM02328.1 - 0.024 14.6 0.6 0.093 12.8 0.4 1.9 1 1 0 1 1 1 0 Stc1 domain Pro_isomerase PF00160.16 CCM02329.1 - 8e-37 126.8 0.0 1.2e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CCM02329.1 - 9.2e-16 57.2 0.0 1.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM02329.1 - 3.3e-12 46.1 0.0 7.6e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM02329.1 - 1.3e-08 34.5 0.1 4e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGEF PF00621.15 CCM02330.1 - 8.6e-20 71.3 0.0 8.4e-16 58.3 0.0 3.2 2 1 0 2 2 2 2 RhoGEF domain EzrA PF06160.7 CCM02330.1 - 1.1 7.3 0.1 11 4.0 0.0 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA LRR_4 PF12799.2 CCM02331.1 - 3.5e-12 45.6 6.1 0.0084 15.7 0.1 7.2 8 0 0 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCM02331.1 - 3.1e-10 38.6 6.7 1.8 8.8 0.1 7.3 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 CCM02331.1 - 2.8e-09 36.0 5.4 1.6 9.0 0.0 8.2 9 0 0 9 9 9 3 Leucine Rich repeat LRR_8 PF13855.1 CCM02331.1 - 0.18 11.6 17.8 0.42 10.3 0.0 5.8 2 2 5 7 7 7 0 Leucine rich repeat LRR_7 PF13504.1 CCM02331.1 - 0.32 11.3 20.7 15 6.3 0.0 8.4 11 0 0 11 11 11 0 Leucine rich repeat Amidohydro_4 PF13147.1 CCM02332.1 - 7.1e-14 52.4 2.6 7.1e-14 52.4 1.8 3.2 3 1 0 3 3 3 1 Amidohydrolase Amidohydro_5 PF13594.1 CCM02332.1 - 1.7e-10 40.5 0.9 5.8e-08 32.4 0.1 2.6 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 CCM02332.1 - 2.4e-06 27.4 0.1 0.00099 18.8 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 CCM02332.1 - 7.8e-06 25.3 1.5 0.0017 17.6 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family zf-RING_2 PF13639.1 CCM02334.1 - 6.6e-09 35.4 11.8 1.1e-08 34.7 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCM02334.1 - 7.7e-07 28.7 11.2 1.3e-06 28.0 7.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCM02334.1 - 1.3e-06 28.3 13.7 2.1e-06 27.6 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCM02334.1 - 5.8e-06 25.8 14.5 9.8e-06 25.1 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM02334.1 - 1.3e-05 24.9 15.2 2.3e-05 24.1 10.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCM02334.1 - 0.00064 19.3 13.4 0.0013 18.3 9.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger DUF342 PF03961.8 CCM02334.1 - 0.00081 17.9 1.5 0.0011 17.4 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) TerY-C PF15616.1 CCM02334.1 - 0.0033 17.3 2.8 0.0064 16.4 2.0 1.4 1 0 0 1 1 1 1 TerY-C metal binding domain AATF-Che1 PF13339.1 CCM02334.1 - 0.011 15.8 2.0 0.087 12.9 1.0 2.4 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor TMF_DNA_bd PF12329.3 CCM02334.1 - 0.017 14.8 2.1 0.017 14.8 1.4 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CCM02334.1 - 0.043 13.4 3.7 0.093 12.3 2.6 1.5 1 0 0 1 1 1 0 IncA protein C1_3 PF07649.7 CCM02334.1 - 0.051 13.6 3.0 0.13 12.3 2.1 1.7 1 0 0 1 1 1 0 C1-like domain zf-rbx1 PF12678.2 CCM02334.1 - 0.051 13.6 5.4 0.13 12.3 3.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CCM02334.1 - 0.068 12.7 10.3 0.13 11.8 7.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF904 PF06005.7 CCM02334.1 - 0.08 13.2 4.9 3.4 8.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 CCM02334.1 - 0.16 10.9 2.5 0.3 10.0 1.7 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CCM02334.1 - 0.21 11.0 6.1 1.7 8.1 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator Prok-RING_1 PF14446.1 CCM02334.1 - 0.23 11.2 8.1 0.1 12.3 1.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_3 PF14369.1 CCM02334.1 - 0.29 11.1 6.0 0.51 10.3 1.3 2.5 2 0 0 2 2 2 0 zinc-finger Prok-RING_4 PF14447.1 CCM02334.1 - 0.3 10.6 11.0 1.2 8.7 7.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TBPIP PF07106.8 CCM02334.1 - 0.52 9.8 7.2 2.4 7.6 5.0 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1090 PF06476.7 CCM02334.1 - 1 9.0 9.1 2.2 7.9 6.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) zf-RING_6 PF14835.1 CCM02334.1 - 1.6 8.5 6.2 4 7.2 4.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 CCM02334.1 - 1.7 8.1 8.7 4.5 6.8 6.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4140 PF13600.1 CCM02334.1 - 4.9 7.6 8.5 6.2 7.3 1.4 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DctQ PF04290.7 CCM02335.1 - 0.0024 17.6 1.9 0.0024 17.6 1.3 2.3 3 1 0 3 3 3 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1109 PF06532.6 CCM02335.1 - 0.01 15.2 12.2 0.022 14.1 8.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1109) TMEM164 PF14808.1 CCM02335.1 - 0.08 12.1 2.1 0.11 11.7 0.1 1.9 2 0 0 2 2 2 0 TMEM164 family LIME1 PF15332.1 CCM02336.1 - 0.078 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 MFS_1 PF07690.11 CCM02337.1 - 4.8e-35 120.9 48.7 9.8e-35 119.8 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Septin PF00735.13 CCM02339.1 - 4.1e-113 377.0 0.2 5.9e-113 376.5 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCM02339.1 - 1.1e-06 28.5 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCM02339.1 - 1.3e-06 27.7 0.0 3.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCM02339.1 - 3.5e-06 26.5 0.1 0.00016 21.2 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCM02339.1 - 0.00058 20.3 0.0 0.0016 18.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CCM02339.1 - 0.0018 17.7 0.5 0.082 12.3 0.1 2.5 2 1 0 2 2 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 CCM02339.1 - 0.0034 17.3 0.6 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 CCM02339.1 - 0.0049 17.1 0.1 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 CCM02339.1 - 0.0058 16.7 2.4 0.011 15.8 0.1 2.6 2 2 0 2 2 2 1 AAA domain AIG1 PF04548.11 CCM02339.1 - 0.006 15.7 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_10 PF12846.2 CCM02339.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 CCM02339.1 - 0.019 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 CCM02339.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CCM02339.1 - 0.023 14.5 6.9 1 9.1 0.0 2.9 2 1 1 3 3 3 0 Dynamin family Ras PF00071.17 CCM02339.1 - 0.028 13.7 0.1 0.081 12.3 0.1 1.8 1 1 0 1 1 1 0 Ras family AAA_14 PF13173.1 CCM02339.1 - 0.034 14.0 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CCM02339.1 - 0.042 13.3 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 CCM02339.1 - 0.049 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CCM02339.1 - 0.055 12.3 0.4 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 CCM02339.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CCM02339.1 - 0.087 12.6 0.7 0.23 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CCM02339.1 - 0.09 12.3 0.2 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 CCM02339.1 - 0.13 11.7 0.2 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Aldo_ket_red PF00248.16 CCM02341.1 - 7e-38 130.0 0.0 8.2e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CCM02342.1 - 4.3e-48 163.5 0.0 5.3e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Asn_synthase PF00733.16 CCM02343.1 - 4.4e-73 245.9 0.0 6e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCM02343.1 - 1.3e-35 121.8 0.0 2.2e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCM02343.1 - 1.2e-28 99.6 0.0 5.7e-28 97.5 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CCM02343.1 - 0.0025 17.0 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 CCM02343.1 - 0.0069 15.1 0.0 0.026 13.2 0.0 1.8 1 1 1 2 2 2 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 CCM02343.1 - 0.01 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 NAD synthase QueC PF06508.8 CCM02343.1 - 0.039 13.2 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC RhoGEF PF00621.15 CCM02344.1 - 0.052 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain TFIIA PF03153.8 CCM02344.1 - 3 7.6 9.5 5 6.9 6.5 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_16 PF10294.4 CCM02345.1 - 8.4e-16 57.9 0.0 1.3e-12 47.5 0.0 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CCM02345.1 - 0.00013 21.6 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM02345.1 - 0.00017 22.1 0.0 0.00029 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CCM02345.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Gluconate_2-dh3 PF13618.1 CCM02346.1 - 0.0088 16.1 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Gluconate 2-dehydrogenase subunit 3 Phage_Gp15 PF06854.6 CCM02346.1 - 0.027 13.9 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Gp15 protein EF_assoc_1 PF08355.7 CCM02346.1 - 0.048 12.9 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 EF hand associated EF-hand_8 PF13833.1 CCM02346.1 - 0.055 13.0 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF_assoc_2 PF08356.7 CCM02346.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 EF hand associated DEAD PF00270.24 CCM02347.1 - 3e-41 140.7 0.0 2.9e-40 137.5 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM02347.1 - 4.3e-25 87.3 0.1 1.2e-24 85.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM02347.1 - 0.014 15.2 0.1 0.051 13.4 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PNRC PF15365.1 CCM02347.1 - 0.27 11.2 6.6 0.91 9.5 4.6 1.9 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Pkinase PF00069.20 CCM02348.1 - 1.4e-54 184.9 0.0 6.3e-54 182.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02348.1 - 1.5e-26 93.0 0.0 3.1e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM02348.1 - 0.0034 17.1 0.2 0.018 14.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCM02348.1 - 0.019 13.9 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PRKCSH PF07915.8 CCM02349.1 - 5.2e-12 46.4 0.2 9.4e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 CCM02349.1 - 0.0018 17.7 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Phage_integ_N PF09003.5 CCM02349.1 - 0.36 10.5 0.1 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage lambda integrase, N-terminal domain AT_hook PF02178.14 CCM02350.1 - 0.00021 20.6 59.2 0.05 13.2 5.1 4.5 4 0 0 4 4 4 4 AT hook motif FAD_binding_3 PF01494.14 CCM02351.1 - 1.4e-20 73.6 0.0 2.2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CCM02351.1 - 3.8e-06 27.2 0.1 8.6e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM02351.1 - 1.1e-05 24.5 0.0 0.00026 20.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCM02351.1 - 2.4e-05 24.2 0.0 9.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM02351.1 - 0.00016 21.6 0.0 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CCM02351.1 - 0.001 18.0 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CCM02351.1 - 0.0039 16.3 0.1 0.031 13.3 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCM02351.1 - 0.0052 15.3 0.0 0.01 14.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 CCM02351.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CCM02351.1 - 0.048 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CCM02351.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.5 CCM02351.1 - 0.072 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.19 CCM02351.1 - 0.079 11.7 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 CCM02351.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.24 CCM02352.1 - 3.5e-37 127.5 0.0 9.2e-37 126.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCM02352.1 - 2.1e-05 24.5 5.0 0.0038 17.2 0.0 4.7 4 2 2 6 6 6 1 AAA ATPase domain AAA_22 PF13401.1 CCM02352.1 - 3.8e-05 23.8 0.0 0.04 14.0 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CCM02352.1 - 0.00039 20.1 0.1 0.003 17.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCM02352.1 - 0.00047 20.9 0.1 0.0038 18.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM02352.1 - 0.0014 18.3 0.1 0.0052 16.5 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CCM02352.1 - 0.0024 17.4 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CCM02352.1 - 0.0034 16.8 0.2 2.4 7.5 0.0 3.1 2 1 1 3 3 3 1 AAA-like domain DUF815 PF05673.8 CCM02352.1 - 0.0088 14.9 0.0 0.024 13.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 CCM02352.1 - 0.0095 15.3 0.4 3 7.1 0.1 3.4 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 CCM02352.1 - 0.017 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCM02352.1 - 0.023 14.1 0.0 0.086 12.2 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 CCM02352.1 - 0.023 14.9 0.1 0.67 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 CCM02352.1 - 0.032 12.9 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 CCM02352.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CCM02352.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_Nse1 PF07574.8 CCM02353.1 - 5.5e-23 81.6 0.2 2.8e-13 49.9 0.0 2.2 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CCM02353.1 - 3.7e-08 33.2 11.0 6.7e-08 32.4 7.6 1.5 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 CCM02353.1 - 8.4e-05 22.3 8.4 0.00016 21.4 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.1 CCM02353.1 - 0.00035 20.6 2.7 0.00088 19.3 1.8 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CCM02353.1 - 0.00075 19.4 1.8 0.0016 18.4 1.3 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain Baculo_IE-1 PF05290.6 CCM02353.1 - 0.015 15.0 0.8 0.026 14.2 0.6 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 CCM02353.1 - 0.019 15.0 3.4 0.044 13.9 2.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Baculo_RING PF05883.6 CCM02353.1 - 0.021 14.6 1.6 0.045 13.5 1.1 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_2 PF13923.1 CCM02353.1 - 0.14 12.2 9.2 0.25 11.4 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CCM02353.1 - 0.21 11.3 8.2 0.45 10.2 5.7 1.6 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 CCM02353.1 - 0.45 10.2 6.3 0.86 9.3 4.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 CCM02353.1 - 0.93 9.2 7.0 1.6 8.4 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM02353.1 - 2.2 8.0 10.2 3.8 7.3 7.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Di19 PF05605.7 CCM02353.1 - 4.4 7.4 7.3 3.7 7.7 1.5 2.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding CDP-OH_P_transf PF01066.16 CCM02354.1 - 1.4e-12 47.8 4.3 2.9e-12 46.7 2.9 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DNA_primase_lrg PF04104.9 CCM02355.1 - 2.4e-84 282.6 0.0 3.9e-84 281.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit USP7_ICP0_bdg PF12436.3 CCM02357.1 - 7.8e-84 280.8 0.3 3.8e-83 278.5 0.1 2.2 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 CCM02357.1 - 4.2e-68 228.9 7.5 1.3e-67 227.3 1.4 2.9 3 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 CCM02357.1 - 3.9e-57 193.3 0.1 7.2e-57 192.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM02357.1 - 1.2e-30 106.9 0.0 1.9e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CCM02357.1 - 3.4e-09 36.9 0.5 4.2e-07 30.2 0.0 3.8 3 2 0 3 3 3 1 MATH domain UN_NPL4 PF11543.3 CCM02357.1 - 0.0018 18.5 1.0 2.4 8.5 0.0 3.6 4 0 0 4 4 4 2 Nuclear pore localisation protein NPL4 ubiquitin PF00240.18 CCM02357.1 - 0.0025 17.1 0.1 0.25 10.7 0.0 3.5 3 0 0 3 3 3 1 Ubiquitin family Sec66 PF09802.4 CCM02358.1 - 3.4e-52 176.5 0.1 4.3e-52 176.2 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Citrate_synt PF00285.16 CCM02359.1 - 1.8e-100 336.1 0.0 2.2e-100 335.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Zip PF02535.17 CCM02360.1 - 0.69 8.8 2.1 0.9 8.4 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 CCM02360.1 - 6.3 6.0 12.1 12 5.1 8.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region B56 PF01603.15 CCM02361.1 - 2.4e-170 566.5 8.8 2.9e-170 566.2 6.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Glyco_transf_15 PF01793.11 CCM02362.1 - 4.7e-23 81.6 0.2 5.1e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4071 PF13281.1 CCM02362.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Glyco_transf_15 PF01793.11 CCM02363.1 - 4.3e-60 203.3 1.2 5.1e-60 203.1 0.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PI3_PI4_kinase PF00454.22 CCM02364.1 - 3.8e-31 108.3 0.0 7.2e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase OST3_OST6 PF04756.8 CCM02365.1 - 2.2e-15 56.5 3.4 3.4e-15 55.9 2.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 CCM02365.1 - 0.00022 20.8 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF4149 PF13664.1 CCM02365.1 - 0.033 14.2 4.4 0.22 11.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) HlyE PF06109.8 CCM02365.1 - 0.094 11.7 0.0 1.9 7.4 0.0 2.0 2 0 0 2 2 2 0 Haemolysin E (HlyE) EpsG PF14897.1 CCM02365.1 - 0.11 11.3 6.3 0.93 8.3 0.7 2.3 2 0 0 2 2 2 0 EpsG family CHZ PF09649.5 CCM02365.1 - 1 8.6 3.0 1 8.6 0.1 2.3 3 0 0 3 3 3 0 Histone chaperone domain CHZ 7TMR-DISM_7TM PF07695.6 CCM02365.1 - 3.2 7.3 12.5 0.53 9.9 5.4 2.0 2 1 0 2 2 2 0 7TM diverse intracellular signalling Sec16_C PF12931.2 CCM02366.1 - 1.2e-69 235.2 0.0 2.2e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CCM02366.1 - 2e-30 105.1 0.1 1.6e-29 102.2 0.0 2.6 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region PUF PF00806.14 CCM02367.1 - 1.7e-60 197.2 1.6 1.8e-08 33.3 0.0 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Kinesin PF00225.18 CCM02368.1 - 5.5e-113 377.0 0.2 1.2e-112 375.9 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF3584 PF12128.3 CCM02368.1 - 1.2 6.3 69.0 0.052 10.8 15.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.16 CCM02368.1 - 7.7 5.8 69.4 0.57 9.5 27.5 3.6 3 1 1 4 4 4 0 Intermediate filament protein Elf1 PF05129.8 CCM02369.1 - 1.8e-27 94.8 0.2 2.2e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 CCM02369.1 - 0.005 16.9 0.4 0.0073 16.4 0.3 1.2 1 0 0 1 1 1 1 CHY zinc finger Kinesin PF00225.18 CCM02370.1 - 1.3e-109 365.9 0.0 2.3e-109 365.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Vps55 PF04133.9 CCM02370.1 - 8.3e-39 132.0 1.4 1.4e-38 131.3 1.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Microtub_bind PF13931.1 CCM02370.1 - 0.00025 21.1 0.3 0.00025 21.1 0.2 4.3 3 1 1 4 4 4 1 Kinesin-associated microtubule-binding Carbpep_Y_N PF05388.6 CCM02370.1 - 0.1 12.7 0.3 1.5 9.0 0.1 2.9 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide TRAPPC9-Trs120 PF08626.6 CCM02371.1 - 7.7e-112 374.6 0.0 1.5e-85 287.5 0.0 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit C1_1 PF00130.17 CCM02372.1 - 2e-06 27.4 14.7 1e-05 25.1 2.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.1 CCM02372.1 - 0.00019 19.9 0.1 0.0005 18.5 0.0 1.6 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 PHD PF00628.24 CCM02372.1 - 0.066 12.9 14.7 0.5 10.1 2.5 2.5 2 0 0 2 2 2 0 PHD-finger DZR PF12773.2 CCM02372.1 - 0.079 12.7 4.5 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon PHD_2 PF13831.1 CCM02372.1 - 3.1 7.2 9.8 4.7 6.6 1.0 2.8 2 0 0 2 2 2 0 PHD-finger DUF4211 PF13926.1 CCM02373.1 - 1.7e-30 105.4 0.3 6.3e-30 103.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) TFIID-18kDa PF02269.11 CCM02374.1 - 9.9e-22 76.5 0.1 1.4e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit RRM_1 PF00076.17 CCM02375.1 - 2.5e-15 55.8 0.1 6.3e-15 54.5 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM02375.1 - 1.4e-14 53.8 0.0 1.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM02375.1 - 1.7e-08 34.1 0.0 1.4e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CCM02375.1 - 0.015 15.0 0.0 0.036 13.7 0.0 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 CCM02376.1 - 5.3e-12 45.4 0.0 1.8e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CCM02376.1 - 0.00016 20.7 0.1 0.00025 20.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM02376.1 - 0.0009 19.0 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM02376.1 - 0.22 11.0 0.6 0.37 10.3 0.4 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2040 PF09745.4 CCM02377.1 - 5.7e-35 119.9 21.8 5.7e-35 119.9 15.1 3.4 2 2 2 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) NAD_binding_4 PF07993.7 CCM02378.1 - 1.8e-31 108.9 0.0 2.8e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RNase_PH PF01138.16 CCM02378.1 - 9.4e-28 97.1 0.6 2.8e-27 95.6 0.2 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 AMP-binding PF00501.23 CCM02378.1 - 2.5e-19 69.0 0.1 2.1e-17 62.6 0.0 3.0 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 CCM02378.1 - 5.8e-10 39.0 0.0 9.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CCM02378.1 - 0.0043 17.2 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 CCM02378.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase AA_permease_2 PF13520.1 CCM02379.1 - 6.5e-66 222.6 39.7 8.9e-66 222.1 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCM02379.1 - 1.2e-28 99.6 36.7 1.6e-28 99.3 25.4 1.1 1 0 0 1 1 1 1 Amino acid permease HMA PF00403.21 CCM02379.1 - 5e-12 45.7 2.3 8.1e-12 45.1 1.6 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Ribosomal_S9 PF00380.14 CCM02379.1 - 0.16 12.2 0.0 2.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S9/S16 DUF3133 PF11331.3 CCM02379.1 - 3 7.4 5.6 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) Ferric_reduct PF01794.14 CCM02380.1 - 5.9e-17 61.9 14.4 5.9e-17 61.9 10.0 2.5 2 2 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CCM02380.1 - 7e-11 41.9 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CCM02380.1 - 8.6e-07 28.9 0.1 0.0037 17.1 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain TRM PF02005.11 CCM02381.1 - 2.2e-119 398.7 0.0 3.3e-119 398.1 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 CCM02381.1 - 0.0046 16.9 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 CCM02381.1 - 0.022 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase zf-H2C2_2 PF13465.1 CCM02381.1 - 0.046 14.0 0.9 0.046 14.0 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Methyltransf_18 PF12847.2 CCM02381.1 - 0.071 13.6 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain C1_3 PF07649.7 CCM02381.1 - 0.11 12.4 3.6 7.8 6.6 0.1 3.0 2 0 0 2 2 2 0 C1-like domain Met_10 PF02475.11 CCM02381.1 - 0.17 11.4 0.2 0.67 9.5 0.2 2.1 1 1 0 1 1 1 0 Met-10+ like-protein Pkinase PF00069.20 CCM02382.1 - 7.7e-71 238.2 0.0 1.1e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02382.1 - 8.1e-50 169.2 0.0 1.3e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CCM02382.1 - 3.5e-10 39.7 0.0 6.9e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.1 CCM02382.1 - 1.4e-06 27.4 0.0 0.00014 20.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCM02382.1 - 0.096 12.3 0.2 7.5 6.2 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Y1_Tnp PF01797.11 CCM02382.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Transposase IS200 like Nop14 PF04147.7 CCM02382.1 - 0.31 8.9 12.8 0.42 8.4 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 CCM02382.1 - 0.46 9.4 5.1 0.84 8.5 3.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 CCM02382.1 - 5.8 6.0 9.0 8.6 5.5 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 CCM02382.1 - 9.5 4.5 17.6 0.19 10.1 7.5 1.5 2 0 0 2 2 2 0 Daxx Family Alpha-amylase PF00128.19 CCM02383.1 - 2.9e-19 69.6 2.5 2.9e-19 69.6 1.7 3.6 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 CCM02383.1 - 1.5e-14 54.1 0.0 2.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 CCM02383.1 - 2.9e-08 33.3 0.0 5.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCM02383.1 - 1e-07 32.2 0.0 2.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_11 PF08241.7 CCM02384.1 - 7.3e-13 48.8 0.0 1.4e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM02384.1 - 1.6e-07 31.1 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM02384.1 - 1.9e-06 28.3 0.0 1.3e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM02384.1 - 6e-06 26.6 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM02384.1 - 1.5e-05 25.0 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM02384.1 - 4.4e-05 23.1 0.0 0.00029 20.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM02384.1 - 0.00027 21.2 0.0 0.00066 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM02384.1 - 0.0064 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 CCM02384.1 - 0.049 13.0 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.12 CCM02384.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 CCM02384.1 - 0.078 13.8 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CCM02384.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DAGK_cat PF00781.19 CCM02385.1 - 2.2e-24 85.3 0.0 4.1e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Abhydrolase_3 PF07859.8 CCM02387.1 - 4.9e-49 166.7 0.0 6.4e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CCM02387.1 - 5.4e-07 28.6 0.0 1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 CCM02387.1 - 0.034 13.4 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family F-box-like PF12937.2 CCM02388.1 - 3.9e-07 29.6 0.0 1.9e-06 27.4 0.0 2.3 1 0 0 1 1 1 1 F-box-like Speriolin_C PF15059.1 CCM02388.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Speriolin C-terminus HSP90 PF00183.13 CCM02389.1 - 2.7e-251 834.6 31.9 3.3e-251 834.3 22.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CCM02389.1 - 1.9e-11 43.6 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCM02389.1 - 2.4e-10 40.2 0.3 2.4e-10 40.2 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 CCM02389.1 - 0.79 9.0 19.1 0.023 14.0 7.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Peptidase_C37 PF05416.7 CCM02389.1 - 4.3 5.5 8.5 2.2 6.4 0.2 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase HALZ PF02183.13 CCM02390.1 - 0.034 13.8 2.5 0.04 13.6 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.6 CCM02390.1 - 0.078 11.6 19.4 0.43 9.1 0.6 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein V-SNARE PF05008.10 CCM02390.1 - 0.084 13.0 0.2 0.084 13.0 0.1 3.7 4 1 1 5 5 5 0 Vesicle transport v-SNARE protein N-terminus FlaC_arch PF05377.6 CCM02390.1 - 0.2 11.5 2.3 3.5 7.6 0.2 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 CCM02390.1 - 9.3 4.5 20.9 1.5 7.1 1.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Cerato-platanin PF07249.7 CCM02392.1 - 1.3e-29 102.6 1.7 1.5e-29 102.3 1.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 CCM02392.1 - 0.0091 15.6 1.0 0.017 14.7 0.7 1.4 1 1 0 1 1 1 1 Barwin family DUF1264 PF06884.6 CCM02393.1 - 1.7e-67 226.1 0.0 2.4e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF1958 PF09211.5 CCM02393.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1958) DUF3816 PF12822.2 CCM02394.1 - 7.3 6.4 15.4 1e+03 -0.6 10.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) NAC PF01849.13 CCM02395.1 - 6.5e-21 73.6 0.0 1.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 CCM02395.1 - 0.0023 17.7 0.2 0.0059 16.4 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CCM02395.1 - 0.029 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Methyltransf_11 PF08241.7 CCM02396.1 - 4.4e-07 30.3 0.0 1e-06 29.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM02396.1 - 0.014 15.9 0.0 0.024 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CCM02396.1 - 0.017 14.7 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCM02396.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_tran_28_C PF04101.11 CCM02397.1 - 1.8e-31 109.0 0.0 2.1e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CCM02397.1 - 1.9e-05 24.0 0.0 2.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 P5CR_dimer PF14748.1 CCM02398.1 - 2.1e-39 133.8 4.0 4.6e-39 132.7 0.8 2.6 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CCM02398.1 - 0.00027 21.3 0.0 0.42 11.0 0.0 2.7 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.24 CCM02399.1 - 1.8e-44 151.0 0.1 5e-44 149.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCM02399.1 - 6.7e-09 35.5 0.1 2.3e-08 33.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCM02399.1 - 7.1e-08 32.5 0.2 2.9e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCM02399.1 - 3.6e-07 30.3 0.3 1.8e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCM02399.1 - 1.3e-06 28.5 0.7 0.00036 20.6 0.4 3.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CCM02399.1 - 2.5e-06 26.6 0.0 5.5e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CCM02399.1 - 0.00012 22.0 0.0 0.0004 20.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CCM02399.1 - 0.00012 21.9 0.0 0.00065 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM02399.1 - 0.00017 21.2 0.1 0.00047 19.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CCM02399.1 - 0.00073 18.6 0.0 0.0017 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CCM02399.1 - 0.00087 18.7 0.8 0.013 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CCM02399.1 - 0.00098 19.9 0.1 0.0048 17.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCM02399.1 - 0.0012 19.1 0.0 0.011 16.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CCM02399.1 - 0.0015 18.2 0.1 0.0072 16.0 0.0 2.2 3 0 0 3 3 1 1 NTPase NACHT PF05729.7 CCM02399.1 - 0.0017 18.0 0.1 0.057 13.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.8 CCM02399.1 - 0.0018 17.0 0.0 0.0035 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 CCM02399.1 - 0.0023 18.1 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 CCM02399.1 - 0.0025 17.4 0.1 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCM02399.1 - 0.003 17.1 0.1 0.024 14.2 0.0 2.2 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 CCM02399.1 - 0.0032 16.9 0.7 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 CCM02399.1 - 0.0056 16.5 0.0 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCM02399.1 - 0.0067 16.0 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCM02399.1 - 0.0073 15.4 0.1 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI CENP-F_leu_zip PF10473.4 CCM02399.1 - 0.0079 16.0 1.5 0.015 15.1 1.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_30 PF13604.1 CCM02399.1 - 0.011 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CCM02399.1 - 0.016 14.8 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCM02399.1 - 0.021 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 CCM02399.1 - 0.021 14.5 1.5 0.25 11.0 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase AFG1_ATPase PF03969.11 CCM02399.1 - 0.023 13.5 0.0 0.06 12.1 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.13 CCM02399.1 - 0.038 13.6 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 CCM02399.1 - 0.061 12.7 0.2 1.2 8.6 0.0 2.8 3 1 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.22 CCM02399.1 - 0.096 12.9 0.1 0.72 10.1 0.0 2.5 3 0 0 3 3 2 0 ABC transporter Parvo_NS1 PF01057.12 CCM02399.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 CCM02399.1 - 0.13 11.3 1.1 0.44 9.6 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.1 CCM02399.1 - 0.22 11.7 4.3 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 CCM02400.1 - 7.8e-13 47.8 0.0 1.9e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM02400.1 - 1.2e-09 38.0 0.0 1.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM02400.1 - 7.2e-06 25.7 0.0 1.7e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3826 PF12875.2 CCM02400.1 - 0.017 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) RRM_6 PF14259.1 CCM02401.1 - 2.7e-09 36.8 0.0 1.5e-06 28.1 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCM02401.1 - 0.017 14.7 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bac_rhodopsin PF01036.13 CCM02402.1 - 5.9e-40 136.9 19.7 8e-40 136.5 13.7 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Arteri_Gl PF00951.13 CCM02402.1 - 0.87 9.1 9.9 0.051 13.1 3.1 1.7 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein ABC2_membrane_5 PF13346.1 CCM02402.1 - 1 8.6 15.3 0.29 10.3 6.2 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1777 PF08648.7 CCM02403.1 - 3.5e-19 69.2 28.0 3.5e-19 69.2 19.4 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1777) SRP-alpha_N PF04086.8 CCM02403.1 - 4.4 6.5 6.0 6.7 6.0 4.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SUI1 PF01253.17 CCM02404.1 - 2.9e-26 91.0 0.4 2.1e-13 49.8 0.1 2.1 2 0 0 2 2 2 2 Translation initiation factor SUI1 rRNA_processing PF08524.6 CCM02405.1 - 0.0091 15.7 18.2 3.8e+02 0.8 12.6 2.4 1 1 0 1 1 1 0 rRNA processing DUF2890 PF11081.3 CCM02405.1 - 0.34 10.9 15.3 0.45 10.5 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Spore_coat_CotO PF14153.1 CCM02405.1 - 3.6 6.9 9.1 4.5 6.6 6.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PPP4R2 PF09184.6 CCM02406.1 - 1.1e-21 77.6 0.1 1.9e-21 76.9 0.0 1.4 2 0 0 2 2 2 1 PPP4R2 PAP2 PF01569.16 CCM02407.1 - 9.3e-29 99.7 2.6 1.5e-28 99.0 1.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF4593 PF15263.1 CCM02408.1 - 0.083 12.7 2.5 0.18 11.6 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) RabGAP-TBC PF00566.13 CCM02409.1 - 1.4e-41 142.3 5.7 1.3e-38 132.5 1.4 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 CCM02409.1 - 3.4e-09 36.2 0.1 3.6e-05 23.1 0.0 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) ox_reductase_C PF08635.5 CCM02410.1 - 9.1e-73 242.3 0.1 1.5e-72 241.6 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal Ribosomal_S21e PF01249.13 CCM02410.1 - 2.4e-35 120.3 0.0 6.6e-35 118.9 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S21e GFO_IDH_MocA PF01408.17 CCM02410.1 - 2e-17 63.7 0.0 4.6e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCM02410.1 - 0.093 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain HALZ PF02183.13 CCM02410.1 - 0.1 12.3 0.5 0.2 11.3 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DcpS_C PF11969.3 CCM02411.1 - 6.9e-14 52.0 0.1 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CCM02411.1 - 3.6e-09 37.0 0.0 7.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 HIT domain SAP PF02037.22 CCM02413.1 - 2.4e-10 39.6 0.5 7.5e-10 38.0 0.4 1.8 2 0 0 2 2 2 1 SAP domain DUF2315 PF10231.4 CCM02414.1 - 1.3e-13 50.9 8.6 1.6e-11 44.2 6.0 2.1 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2315) DUF2524 PF10732.4 CCM02414.1 - 0.015 15.4 0.6 0.026 14.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) Nucleoporin_C PF03177.9 CCM02415.1 - 4.2e-54 184.0 5.0 6.9e-54 183.3 3.5 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCM02415.1 - 9.8e-11 41.0 0.0 2.3e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Exonuc_VII_L PF02601.10 CCM02415.1 - 0.19 10.8 1.3 0.3 10.2 0.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit PRCC PF10253.4 CCM02416.1 - 2.2e-28 100.1 0.1 2.2e-28 100.1 0.0 2.0 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Histone PF00125.19 CCM02417.1 - 1.9e-20 72.7 0.2 3.1e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCM02417.1 - 0.00023 21.1 1.5 0.00024 21.0 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCM02417.1 - 0.0018 18.5 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A MaoC_dehydratas PF01575.14 CCM02417.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain DUF3408 PF11888.3 CCM02417.1 - 0.31 10.9 4.1 0.64 9.9 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Aminotran_5 PF00266.14 CCM02419.1 - 4.2e-35 121.1 0.0 8.6e-35 120.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V SKN1 PF03935.10 CCM02420.1 - 2e-06 26.2 0.0 2.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.1 CCM02420.1 - 9.7e-05 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Neurensin His_Phos_2 PF00328.17 CCM02422.1 - 0.0053 16.1 0.4 0.14 11.5 0.3 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) EF-hand_1 PF00036.27 CCM02425.1 - 5.9e-43 140.9 12.6 2.6e-10 38.8 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCM02425.1 - 3.1e-38 129.7 3.7 5.3e-21 74.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CCM02425.1 - 2.8e-34 116.4 11.1 2.5e-16 59.0 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CCM02425.1 - 1.1e-31 105.8 7.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CCM02425.1 - 2.4e-28 96.1 7.3 8.3e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CCM02425.1 - 7.2e-15 54.6 0.2 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CCM02425.1 - 2.5e-10 40.0 0.7 6.6e-05 22.5 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CCM02425.1 - 4.8e-09 36.2 0.0 0.00049 20.1 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CCM02425.1 - 1.5e-08 34.1 0.1 0.0085 15.6 0.0 3.8 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CCM02425.1 - 2e-06 27.6 1.3 2.7e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 CCM02425.1 - 0.00033 20.1 1.2 0.00037 19.9 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 CCM02425.1 - 0.00056 19.5 0.1 0.036 13.6 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein EF-hand_like PF09279.6 CCM02425.1 - 0.0006 19.7 0.4 0.011 15.7 0.0 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 CCM02425.1 - 0.0023 17.6 0.1 0.27 10.9 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB Poly_export PF02563.11 CCM02425.1 - 0.019 14.6 0.1 3.8 7.3 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein Tenui_NCP PF04876.7 CCM02425.1 - 0.039 13.5 0.1 0.78 9.2 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 CCM02425.1 - 0.048 13.6 1.2 8.9 6.3 0.1 2.6 3 0 0 3 3 2 0 RNA polymerase Rpb4 Toprim_2 PF13155.1 CCM02425.1 - 0.056 13.7 0.7 13 6.2 0.0 2.4 1 1 0 2 2 2 0 Toprim-like MotA_activ PF09114.5 CCM02425.1 - 0.083 12.6 0.2 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 CCM02425.1 - 0.11 12.0 0.1 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) LRR_6 PF13516.1 CCM02426.1 - 1.1e-10 40.3 19.4 0.033 14.2 0.0 8.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 CCM02426.1 - 2.9e-09 36.3 16.7 0.00063 19.3 0.2 6.1 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM02426.1 - 0.0025 17.5 20.9 0.0027 17.4 0.9 4.9 4 2 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 CCM02426.1 - 0.0035 17.1 14.1 13 6.2 0.0 7.7 8 1 1 9 9 9 1 Leucine Rich Repeat GAT PF03127.9 CCM02426.1 - 0.053 13.5 0.1 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 GAT domain LRR_7 PF13504.1 CCM02426.1 - 0.41 11.0 21.4 9.4 6.9 0.0 8.3 10 0 0 10 10 10 0 Leucine rich repeat Neisseria_TspB PF05616.8 CCM02427.1 - 3.1 6.0 9.3 3.6 5.8 6.4 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein AhpC-TSA PF00578.16 CCM02428.1 - 1.3e-28 99.1 0.0 1.9e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCM02428.1 - 1.8e-18 66.4 0.0 3.2e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin HMG14_17 PF01101.13 CCM02428.1 - 0.00059 20.4 14.4 0.0016 19.0 10.0 1.7 1 0 0 1 1 1 1 HMG14 and HMG17 AhpC-TSA_2 PF13911.1 CCM02428.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme IER PF05760.7 CCM02428.1 - 0.031 14.2 3.3 0.043 13.7 2.3 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) YcfA PF07927.7 CCM02428.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 YcfA-like protein Peptidase_M20 PF01546.23 CCM02429.1 - 1.2e-16 60.7 0.0 1.7e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCM02429.1 - 4.7e-10 39.1 0.0 1e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain RhoGAP PF00620.22 CCM02430.1 - 5.1e-36 123.5 0.0 9.3e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CCM02430.1 - 4.8e-28 97.0 41.8 9e-12 44.8 5.7 4.7 4 0 0 4 4 4 4 LIM domain Ribosomal_S19 PF00203.16 CCM02431.1 - 1.3e-31 108.0 0.2 2e-31 107.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 CCM02431.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Flagellar assembly protein FliH SbcD_C PF12320.3 CCM02431.1 - 0.096 12.7 0.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Ribosomal_60s PF00428.14 CCM02432.1 - 8.5e-29 99.8 11.3 1e-28 99.5 7.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RibD_C PF01872.12 CCM02432.1 - 0.12 11.9 1.1 0.49 9.9 0.1 1.9 1 1 1 2 2 2 0 RibD C-terminal domain Fungal_trans PF04082.13 CCM02433.1 - 1.3e-14 53.7 0.3 1.9e-14 53.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosom_S12_S23 PF00164.20 CCM02433.1 - 0.032 13.6 0.0 0.098 12.0 0.0 1.7 1 1 1 2 2 2 0 Ribosomal protein S12/S23 V-ATPase_G PF03179.10 CCM02434.1 - 1.3e-30 105.8 15.3 1.5e-30 105.5 10.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Glyco_hydro_15 PF00723.16 CCM02434.1 - 0.016 13.7 0.5 0.019 13.5 0.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Neogenin_C PF06583.7 CCM02434.1 - 0.018 14.6 0.6 0.021 14.4 0.4 1.1 1 0 0 1 1 1 0 Neogenin C-terminus DUF3552 PF12072.3 CCM02434.1 - 0.47 9.6 15.2 0.9 8.7 10.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.13 CCM02434.1 - 8.2 6.2 20.6 18 5.1 12.1 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Symplekin_C PF12295.3 CCM02435.1 - 1.3e-57 194.6 0.2 3.1e-57 193.4 0.1 1.7 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 CCM02435.1 - 2.5e-48 164.5 0.2 5.4e-48 163.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) HEAT PF02985.17 CCM02435.1 - 0.05 13.7 0.1 40 4.6 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Adaptin_N PF01602.15 CCM02435.1 - 0.22 9.7 0.0 2.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region RNA_pol_Rpc4 PF05132.9 CCM02436.1 - 1.6e-24 86.3 1.2 4.3e-24 84.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase III RPC4 Pribosyltran PF00156.22 CCM02438.1 - 4.1e-07 29.7 0.0 7.5e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.14 CCM02438.1 - 0.029 13.0 0.0 0.046 12.3 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Mito_carr PF00153.22 CCM02439.1 - 1.7e-72 239.1 3.4 7.8e-24 83.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein KduI PF04962.7 CCM02439.1 - 0.051 12.6 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 KduI/IolB family TFIID_30kDa PF03540.8 CCM02440.1 - 3.1e-27 94.1 0.1 4.6e-27 93.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 CCM02440.1 - 0.13 12.0 0.1 0.32 10.7 0.0 1.7 2 1 0 2 2 2 0 Bromodomain associated Ribosomal_60s PF00428.14 CCM02440.1 - 0.64 10.4 0.0 0.64 10.4 0.0 2.5 2 1 0 2 2 2 0 60s Acidic ribosomal protein GFO_IDH_MocA PF01408.17 CCM02441.1 - 9.2e-17 61.6 0.1 1.5e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SAGA-Tad1 PF12767.2 CCM02442.1 - 8.6e-35 120.6 0.0 1.6e-34 119.7 0.0 1.4 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit STAT6_C PF14596.1 CCM02442.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 STAT6 C-terminal zf-C3HC4_2 PF13923.1 CCM02443.1 - 3.6e-05 23.7 2.4 3.6e-05 23.7 1.7 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 CCM02443.1 - 6e-05 22.6 8.4 0.043 13.5 0.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 CCM02443.1 - 0.00038 20.0 1.1 0.0011 18.5 0.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM02443.1 - 0.00065 19.3 1.1 0.0015 18.2 0.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCM02443.1 - 0.0023 17.7 5.8 0.0024 17.6 2.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCM02443.1 - 0.0085 15.7 2.2 0.036 13.7 1.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LexA_DNA_bind PF01726.11 CCM02443.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Pkinase PF00069.20 CCM02444.1 - 4.5e-43 147.2 0.0 8.3e-43 146.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02444.1 - 6.2e-20 71.3 0.0 2.3e-19 69.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM02444.1 - 0.02 14.6 0.2 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family BCL_N PF04714.8 CCM02444.1 - 0.094 12.2 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 BCL7, N-terminal conserver region ParA PF10609.4 CCM02445.1 - 2.8e-37 126.4 0.0 5.2e-37 125.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCM02445.1 - 7.5e-14 51.5 0.0 1.1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CCM02445.1 - 3.1e-06 26.4 0.5 0.0027 16.8 0.1 2.7 2 1 0 2 2 2 2 Anion-transporting ATPase AAA_25 PF13481.1 CCM02445.1 - 0.00028 20.3 0.3 0.00043 19.7 0.2 1.4 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 CCM02445.1 - 0.00073 19.5 0.0 0.0023 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CCM02445.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YjeF_N PF03853.10 CCM02445.1 - 0.017 14.7 0.0 0.79 9.2 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus YhjQ PF06564.7 CCM02445.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein MipZ PF09140.6 CCM02445.1 - 0.076 12.0 0.0 0.46 9.5 0.0 1.9 1 1 0 1 1 1 0 ATPase MipZ ArgK PF03308.11 CCM02445.1 - 0.098 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 ArgK protein VirE PF05272.6 CCM02445.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Fer4_NifH PF00142.13 CCM02445.1 - 0.13 11.4 0.0 1 8.5 0.0 2.2 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_29 PF13555.1 CCM02445.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.20 CCM02446.1 - 2.5e-73 246.4 0.0 4e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02446.1 - 2.8e-35 121.6 0.0 4.9e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM02446.1 - 0.00026 20.0 0.0 0.00064 18.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCM02446.1 - 0.0049 15.9 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM02446.1 - 0.035 13.8 0.2 0.12 12.0 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF2962 PF11176.3 CCM02447.1 - 5.6e-34 116.9 8.5 6.7e-34 116.6 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Apc15p PF05841.6 CCM02447.1 - 0.34 11.6 0.2 0.34 11.6 0.1 2.2 3 0 0 3 3 3 0 Apc15p protein Fructosamin_kin PF03881.9 CCM02448.1 - 0.19 10.6 0.1 0.29 10.0 0.1 1.2 1 0 0 1 1 1 0 Fructosamine kinase PAT1 PF09770.4 CCM02449.1 - 1.3e-149 499.9 45.3 1.6e-147 493.1 31.4 2.1 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 hDGE_amylase PF14701.1 CCM02450.1 - 4.5e-154 513.4 0.0 5.9e-154 513.0 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CCM02450.1 - 8.3e-111 370.2 0.0 1.2e-110 369.7 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CCM02450.1 - 1.6e-82 276.5 0.0 2.4e-82 276.0 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CCM02450.1 - 4e-17 61.8 0.0 8.8e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 CCM02450.1 - 0.083 12.2 0.0 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, catalytic domain SCA7 PF08313.7 CCM02451.1 - 5.5e-30 102.7 1.0 3.1e-29 100.3 0.1 2.2 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.6 CCM02451.1 - 0.0096 15.2 0.1 0.026 13.8 0.0 1.7 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-TRAF PF02176.13 CCM02451.1 - 0.13 12.6 1.3 0.62 10.4 0.1 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger UbiA PF01040.13 CCM02455.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family Peptidase_C48 PF02902.14 CCM02457.1 - 2.7e-34 118.7 0.1 1.6e-20 73.6 0.1 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SKN1 PF03935.10 CCM02458.1 - 1.3e-200 666.8 10.8 1.6e-200 666.5 7.5 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Mur_ligase_M PF08245.7 CCM02459.1 - 1.3e-09 38.3 0.0 1.2e-07 31.9 0.0 2.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CCM02459.1 - 0.014 15.3 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain RHS_repeat PF05593.9 CCM02460.1 - 1.3e-13 50.7 53.7 0.00011 22.2 0.2 13.0 12 2 4 16 16 16 7 RHS Repeat TcdB_toxin_midN PF12256.3 CCM02460.1 - 1.1e-11 44.5 18.4 0.001 18.5 0.0 8.3 5 1 2 8 8 8 5 Insecticide toxin TcdB middle/N-terminal region VCBS PF13517.1 CCM02460.1 - 1.1e-09 38.4 12.6 2.8e-05 24.4 0.3 5.7 5 0 0 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CCM02460.1 - 2.6e-05 23.7 6.4 0.036 13.7 1.7 3.5 2 0 0 2 2 2 2 FG-GAP repeat RHS PF03527.9 CCM02460.1 - 0.0014 18.3 0.1 0.0084 15.8 0.1 2.4 2 0 0 2 2 2 1 RHS protein CVNH PF08881.5 CCM02462.1 - 9e-07 29.0 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 CVNH domain ThiF PF00899.16 CCM02463.1 - 2.1e-17 63.2 0.0 8e-08 32.1 0.0 2.5 2 0 0 2 2 2 2 ThiF family Fungal_trans PF04082.13 CCM02464.1 - 8.8e-22 77.2 0.1 1.5e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM02464.1 - 2.8e-07 30.3 10.6 2.8e-07 30.3 7.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.1 CCM02465.1 - 0.00039 20.3 0.0 0.0025 17.7 0.0 2.4 2 1 1 3 3 3 1 PPR repeat family Ank_5 PF13857.1 CCM02465.1 - 0.06 13.6 0.1 0.31 11.3 0.1 2.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PPR_1 PF12854.2 CCM02465.1 - 0.17 11.3 0.0 0.52 9.8 0.0 1.9 1 0 0 1 1 1 0 PPR repeat TPR_2 PF07719.12 CCM02465.1 - 0.18 11.8 1.0 2.9 8.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat GRASP55_65 PF04495.9 CCM02466.1 - 7.9e-59 197.6 0.0 1.5e-41 141.6 0.0 2.2 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CCM02466.1 - 0.002 17.9 0.0 2.8 7.8 0.0 3.2 3 0 0 3 3 3 2 PDZ domain BTB PF00651.26 CCM02467.1 - 3.7e-06 26.8 0.0 0.11 12.4 0.0 3.4 3 0 0 3 3 3 3 BTB/POZ domain MATH PF00917.21 CCM02467.1 - 0.00079 19.6 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 MATH domain RRM_1 PF00076.17 CCM02468.1 - 1e-51 172.3 2.0 1.1e-18 66.5 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM02468.1 - 2.2e-43 146.1 0.0 1.2e-14 54.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM02468.1 - 6.1e-22 77.2 0.0 2.5e-07 30.4 0.0 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 CCM02468.1 - 4.4e-05 23.3 0.0 0.43 10.2 0.0 3.3 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) Nup35_RRM_2 PF14605.1 CCM02468.1 - 0.00043 19.9 0.0 0.27 11.0 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TPR_19 PF14559.1 CCM02468.1 - 0.0058 16.9 3.1 3.5 8.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat RRM_3 PF08777.6 CCM02468.1 - 0.012 15.4 0.0 44 4.0 0.0 3.6 3 0 0 3 3 3 0 RNA binding motif DUF4283 PF14111.1 CCM02468.1 - 0.095 11.7 0.1 2.3 7.2 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4283) TPR_14 PF13428.1 CCM02468.1 - 0.24 12.1 9.3 5.7 7.8 0.0 5.3 3 2 2 5 5 5 0 Tetratricopeptide repeat F-box-like PF12937.2 CCM02469.1 - 3.2e-13 49.1 2.1 6.9e-12 44.8 0.3 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM02469.1 - 0.0072 15.9 9.9 0.64 9.7 0.1 4.0 3 1 0 3 3 3 2 F-box domain FAD_binding_2 PF00890.19 CCM02470.1 - 6.8e-50 170.1 7.3 4.1e-43 147.7 0.1 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 CCM02470.1 - 1.4e-08 34.0 7.0 1.6e-07 30.5 4.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CCM02470.1 - 7.2e-08 31.9 6.0 7.8e-05 21.9 1.6 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 CCM02470.1 - 9.3e-06 24.7 7.3 0.00046 19.1 1.0 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 CCM02470.1 - 1.5e-05 25.0 0.6 0.084 12.7 0.9 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM02470.1 - 2.2e-05 23.1 1.0 0.075 11.4 0.2 2.7 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 CCM02470.1 - 4.1e-05 23.7 0.1 0.073 13.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 CCM02470.1 - 4.3e-05 22.8 0.0 0.022 13.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 CCM02470.1 - 0.0017 18.3 1.6 0.0017 18.3 1.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CCM02470.1 - 0.032 13.1 0.3 0.65 8.8 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 CCM02470.1 - 0.15 12.4 0.5 7.4 7.0 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CVNH PF08881.5 CCM02471.1 - 1.6e-15 57.1 0.4 1.8e-15 57.0 0.2 1.1 1 0 0 1 1 1 1 CVNH domain Gamma-thionin PF00304.15 CCM02471.1 - 2 8.4 10.8 1.6 8.8 5.5 2.3 2 1 1 3 3 3 0 Gamma-thionin family PAN_3 PF08277.7 CCM02471.1 - 6.6 6.4 9.3 4 7.1 3.7 2.1 1 1 1 2 2 2 0 PAN-like domain Abhydrolase_6 PF12697.2 CCM02472.1 - 6.3e-11 42.5 0.0 2.2e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Nab2 PF11517.3 CCM02473.1 - 0.099 12.7 0.0 1.9 8.5 0.0 2.5 3 0 0 3 3 3 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Abhydrolase_6 PF12697.2 CCM02474.1 - 2.4e-12 47.2 0.0 5.9e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Herpes_gE PF02480.11 CCM02475.1 - 0.0097 14.2 0.1 0.015 13.5 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 CCM02475.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CD34_antigen PF06365.7 CCM02475.1 - 0.034 13.7 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.1 CCM02475.1 - 0.041 13.5 0.7 0.091 12.4 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family DUF3609 PF12259.3 CCM02475.1 - 0.075 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF3301 PF11743.3 CCM02475.1 - 0.13 11.7 0.2 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) DUF912 PF06024.7 CCM02475.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2371 PF10177.4 CCM02475.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) FixQ PF05545.6 CCM02475.1 - 0.2 11.2 1.2 0.42 10.2 0.8 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ AMA-1 PF02430.10 CCM02475.1 - 0.26 10.1 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 mRNA_triPase PF02940.10 CCM02476.1 - 1.2e-48 165.7 0.0 1.5e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain E1_dh PF00676.15 CCM02477.1 - 2.4e-78 262.9 0.0 3e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Amidase02_C PF12123.3 CCM02477.1 - 0.026 14.1 0.3 0.056 13.1 0.2 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase WD40 PF00400.27 CCM02480.1 - 2.4e-36 122.3 6.5 3.2e-12 45.8 0.7 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 CCM02480.1 - 0.00083 17.6 0.1 0.071 11.2 0.2 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 NACHT PF05729.7 CCM02480.1 - 0.0021 17.7 3.0 0.011 15.3 0.2 2.3 1 1 1 2 2 2 1 NACHT domain Nucleoporin_N PF08801.6 CCM02480.1 - 0.0085 14.8 0.3 0.031 13.0 0.2 1.7 1 1 0 1 1 1 1 Nup133 N terminal like PQQ_2 PF13360.1 CCM02480.1 - 0.013 15.0 0.8 0.16 11.4 0.2 2.3 2 0 0 2 2 2 0 PQQ-like domain RicinB_lectin_2 PF14200.1 CCM02480.1 - 0.11 12.8 0.1 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Sugar_tr PF00083.19 CCM02481.1 - 2e-25 89.2 8.2 2.4e-25 89.0 5.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Pox_I5 PF04713.7 CCM02481.1 - 0.0059 16.2 1.6 0.01 15.5 0.1 1.9 2 0 0 2 2 2 1 Poxvirus protein I5 PhyH PF05721.8 CCM02483.1 - 2e-06 27.9 0.1 0.0074 16.3 0.0 2.4 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Mit_KHE1 PF10173.4 CCM02485.1 - 4.1e-54 183.2 0.4 5.3e-54 182.9 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related F-box-like PF12937.2 CCM02486.1 - 1.7e-06 27.6 0.2 4.7e-06 26.2 0.2 1.9 1 0 0 1 1 1 1 F-box-like GST_C_3 PF14497.1 CCM02486.1 - 0.076 13.5 0.9 10 6.6 0.1 3.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Elong_Iki1 PF10483.4 CCM02486.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA PF00004.24 CCM02487.1 - 6.7e-08 32.8 0.1 2e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCM02487.1 - 5.8e-05 21.9 0.0 0.0012 17.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCM02487.1 - 0.003 17.5 0.1 0.014 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CCM02487.1 - 0.0055 16.4 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CCM02487.1 - 0.05 13.7 0.1 0.38 10.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 CCM02487.1 - 0.053 12.5 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCM02487.1 - 0.06 14.1 1.0 0.17 12.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.8 CCM02487.1 - 0.063 11.9 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Cupin_8 PF13621.1 CCM02488.1 - 3.8e-55 187.1 0.0 5.1e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CCM02488.1 - 9.7e-05 22.5 0.1 0.00027 21.1 0.1 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 CCM02488.1 - 0.065 12.7 0.2 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 Cupin domain Ribosomal_L7Ae PF01248.21 CCM02489.1 - 1.6e-24 85.2 0.9 3.4e-24 84.1 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Calci_bind_CcbP PF11535.3 CCM02489.1 - 0.18 12.0 1.8 0.25 11.6 0.6 1.7 2 0 0 2 2 2 0 Calcium binding DUF603 PF04645.7 CCM02490.1 - 0.042 13.8 6.6 1.4 8.8 0.2 3.3 1 1 2 3 3 3 0 Protein of unknown function, DUF603 UPF0184 PF03670.8 CCM02490.1 - 0.35 11.0 4.0 6 7.1 1.7 3.5 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) NPV_P10 PF05531.7 CCM02490.1 - 0.38 11.0 9.9 29 4.9 0.4 4.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 CCM02490.1 - 6.3 5.7 24.0 0.17 10.9 9.6 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 RFX_DNA_binding PF02257.10 CCM02491.1 - 9.3e-26 89.7 0.0 1.8e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Metallophos PF00149.23 CCM02492.1 - 6.7e-08 32.1 0.8 8.4e-08 31.8 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SpoIIP PF07454.6 CCM02493.1 - 0.033 13.3 0.2 0.045 12.9 0.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AMP-binding PF00501.23 CCM02494.1 - 4.4e-43 147.2 0.0 6.2e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UQ_con PF00179.21 CCM02495.1 - 1.4e-36 125.0 0.1 1.6e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FimP PF09766.4 CCM02496.1 - 1.5e-32 113.0 11.9 1.9e-32 112.7 8.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein DUF948 PF06103.6 CCM02496.1 - 0.0013 18.4 3.2 0.08 12.8 1.4 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 CCM02496.1 - 0.012 15.3 5.1 0.012 15.3 3.5 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4570 PF15134.1 CCM02496.1 - 0.018 14.8 2.3 0.018 14.8 1.6 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) DUF4200 PF13863.1 CCM02496.1 - 0.051 13.5 11.0 0.79 9.6 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Paf67 PF10255.4 CCM02496.1 - 0.058 12.2 2.5 0.075 11.9 1.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 DUF3037 PF11236.3 CCM02496.1 - 0.11 12.5 0.6 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) BLOC1_2 PF10046.4 CCM02496.1 - 0.18 11.9 4.1 0.36 10.9 1.3 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 CCM02496.1 - 0.33 10.9 5.4 0.35 10.9 2.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PAH PF02671.16 CCM02496.1 - 0.58 9.8 2.4 11 5.7 0.6 2.5 2 0 0 2 2 2 0 Paired amphipathic helix repeat DUF3571 PF12095.3 CCM02496.1 - 0.7 10.1 5.4 6.9 6.9 0.6 3.0 2 1 2 4 4 3 0 Protein of unknown function (DUF3571) DUF4446 PF14584.1 CCM02496.1 - 0.86 9.4 5.1 1.1 9.1 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF3450 PF11932.3 CCM02496.1 - 1.7 7.8 10.6 3.9 6.6 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-H PF05837.7 CCM02496.1 - 2.8 8.1 7.5 1.2 9.3 3.1 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Wbp11 PF09429.5 CCM02496.1 - 7.3 6.6 10.4 0.68 9.9 3.6 1.9 2 1 0 2 2 2 0 WW domain binding protein 11 G6PD_C PF02781.11 CCM02497.1 - 4e-124 413.2 0.0 5.2e-124 412.8 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCM02497.1 - 3.2e-60 203.4 0.0 4.6e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G-alpha PF00503.15 CCM02500.1 - 1.5e-106 356.3 0.0 2.1e-106 355.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCM02500.1 - 1.4e-10 40.7 0.0 4.1e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 CCM02500.1 - 0.001 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCM02500.1 - 0.12 12.5 0.0 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CCM02500.1 - 0.13 11.7 0.1 15 5.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein La PF05383.12 CCM02501.1 - 0.00022 20.9 0.3 0.00034 20.3 0.2 1.3 1 0 0 1 1 1 1 La domain adh_short PF00106.20 CCM02502.1 - 4.5e-12 46.2 0.0 1.3e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM02502.1 - 4.6e-08 32.9 0.0 9.3e-08 31.9 0.0 1.4 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CCM02502.1 - 2.6e-05 24.1 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCM02502.1 - 8.7e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM02502.1 - 0.00029 20.8 0.2 0.00056 19.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 CCM02502.1 - 0.00095 19.2 0.4 0.0036 17.4 0.4 1.9 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 CCM02502.1 - 0.0073 15.5 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 CCM02502.1 - 0.016 14.1 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Eno-Rase_NADH_b PF12242.3 CCM02502.1 - 0.037 13.7 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ELFV_dehydrog PF00208.16 CCM02502.1 - 0.048 13.2 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 CCM02502.1 - 0.059 13.0 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 CCM02502.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.14 CCM02502.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 CCM02502.1 - 0.18 11.3 0.4 0.4 10.2 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF883 PF05957.8 CCM02504.1 - 0.00067 19.9 12.3 0.0019 18.5 2.2 2.9 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.1 CCM02504.1 - 3.6 6.4 10.0 5 5.9 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2611 PF11022.3 CCM02505.1 - 0.75 9.9 3.6 2.1 8.4 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2611) FA_desaturase PF00487.19 CCM02507.1 - 1.9e-17 63.5 22.8 3.5e-17 62.7 15.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCM02507.1 - 2.3e-14 52.9 0.1 4.7e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2034 PF10356.4 CCM02508.1 - 1.1e-21 76.7 0.0 1.5e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CCM02508.1 - 0.0013 18.4 0.3 0.0062 16.3 0.2 2.0 1 1 0 1 1 1 1 Restriction endonuclease Transp_cyt_pur PF02133.10 CCM02509.1 - 2.8e-37 128.3 31.3 3.3e-36 124.7 21.7 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4407 PF14362.1 CCM02509.1 - 8.8 5.1 5.5 25 3.6 3.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.13 CCM02512.1 - 0.011 15.4 0.8 0.083 12.6 0.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 CCM02512.1 - 0.19 12.1 0.7 1.2 9.5 0.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 CCM02512.1 - 0.41 10.6 0.1 0.41 10.6 0.0 2.3 2 0 0 2 2 2 0 bZIP transcription factor CsbD PF05532.7 CCM02515.1 - 2.1e-13 49.6 11.6 2.7e-08 33.3 1.7 2.1 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.7 CCM02516.1 - 1.2e-16 60.0 10.2 5.8e-09 35.4 0.8 2.1 1 1 1 2 2 2 2 CsbD-like Spore_III_AF PF09581.5 CCM02516.1 - 0.1 12.4 0.9 0.12 12.2 0.5 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) F-box-like PF12937.2 CCM02517.1 - 6.1e-08 32.2 0.0 2.7e-07 30.1 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM02517.1 - 0.011 15.4 1.5 4.5 7.0 0.3 3.4 2 1 0 2 2 2 0 F-box domain Pkinase_Tyr PF07714.12 CCM02518.1 - 1.2e-46 158.9 0.0 1.7e-44 151.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM02518.1 - 2e-43 148.4 0.0 2e-41 141.8 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 CCM02518.1 - 0.0003 19.9 0.0 0.00063 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM02518.1 - 0.0003 20.1 0.2 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CCM02518.1 - 0.0028 17.4 0.3 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Poty_PP PF08440.5 CCM02518.1 - 0.0092 15.0 0.3 0.038 13.0 0.2 1.9 2 0 0 2 2 2 1 Potyviridae polyprotein BTB PF00651.26 CCM02519.1 - 5.3e-09 36.0 0.0 1.3e-07 31.6 0.0 2.3 1 1 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.11 CCM02520.1 - 1.7e-30 105.9 30.8 5e-30 104.3 21.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 CCM02520.1 - 0.072 11.7 5.5 1.3 7.6 1.1 2.3 2 0 0 2 2 2 0 MMPL family BCS1_N PF08740.6 CCM02522.1 - 4.9e-26 91.4 6.2 7.6e-26 90.8 4.3 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CCM02522.1 - 1.1e-12 48.3 0.0 2.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCM02522.1 - 8.1e-05 23.4 0.9 0.00044 21.0 0.0 2.6 3 2 1 4 4 2 1 AAA domain AAA_16 PF13191.1 CCM02522.1 - 0.00026 21.0 0.3 0.0015 18.5 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CCM02522.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 CCM02522.1 - 0.0035 16.8 0.3 0.027 14.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 CCM02522.1 - 0.0047 15.8 0.0 0.0081 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CCM02522.1 - 0.0059 16.5 0.1 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCM02522.1 - 0.0067 15.5 0.0 0.041 12.9 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CCM02522.1 - 0.0081 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCM02522.1 - 0.0088 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCM02522.1 - 0.0094 15.6 0.1 0.065 12.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 CCM02522.1 - 0.018 15.0 0.2 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CCM02522.1 - 0.018 15.1 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCM02522.1 - 0.023 15.0 0.1 0.086 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CCM02522.1 - 0.026 15.0 0.1 0.27 11.7 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 CCM02522.1 - 0.034 13.7 1.5 0.099 12.2 0.2 2.1 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCM02522.1 - 0.051 13.2 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 CCM02522.1 - 0.055 13.7 0.1 0.94 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCM02522.1 - 0.057 13.7 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 CCM02522.1 - 0.083 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CCM02522.1 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 CCM02522.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus cobW PF02492.14 CCM02522.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 CCM02522.1 - 0.16 11.0 0.0 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 KaiC zf-MYND PF01753.13 CCM02523.1 - 0.039 13.8 16.6 0.12 12.2 11.5 1.8 1 1 0 1 1 1 0 MYND finger BCS1_N PF08740.6 CCM02524.1 - 1.2e-28 100.0 0.6 2.1e-28 99.2 0.4 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CCM02524.1 - 3.7e-15 56.2 0.0 2.2e-14 53.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCM02524.1 - 0.0022 17.0 0.0 0.021 13.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 CCM02524.1 - 0.0083 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CCM02524.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 CCM02524.1 - 0.035 13.2 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 CCM02524.1 - 0.061 12.8 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 CCM02524.1 - 0.073 12.1 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_17 PF13207.1 CCM02524.1 - 0.077 13.8 0.0 0.42 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pantoate_ligase PF02569.10 CCM02526.1 - 9e-80 267.4 0.0 1.7e-78 263.1 0.0 2.0 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Rep_4 PF05797.6 CCM02528.1 - 0.089 11.4 0.9 0.35 9.5 0.6 1.9 1 1 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Flagellin_N PF00669.15 CCM02528.1 - 1.1 9.1 5.0 2 8.2 1.5 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Hemerythrin PF01814.18 CCM02529.1 - 0.066 13.3 0.0 0.08 13.1 0.0 1.1 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Ifi-6-16 PF06140.8 CCM02530.1 - 0.0034 17.1 0.8 0.0034 17.1 0.6 1.8 2 0 0 2 2 2 1 Interferon-induced 6-16 family Glyco_hydro_16 PF00722.16 CCM02531.1 - 8.3e-09 34.9 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.27 CCM02532.1 - 2.1e-38 128.8 9.9 4e-08 32.8 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCM02532.1 - 0.072 11.8 0.0 0.13 11.0 0.0 1.4 1 1 0 1 1 1 0 Nup133 N terminal like SIR2 PF02146.12 CCM02533.1 - 2.6e-27 95.6 0.0 8.7e-27 93.9 0.0 1.7 1 1 0 1 1 1 1 Sir2 family DUF4451 PF14616.1 CCM02535.1 - 0.0054 16.4 1.6 0.031 14.0 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) Ebola_NP PF05505.7 CCM02535.1 - 1.3 7.0 11.6 1.9 6.4 8.1 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Methyltransf_16 PF10294.4 CCM02536.1 - 1.4e-18 66.9 0.0 2.2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCM02536.1 - 2e-07 31.5 0.0 3.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM02536.1 - 0.00091 18.8 0.1 0.008 15.7 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM02536.1 - 0.003 18.0 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 CCM02536.1 - 0.0032 16.6 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.9 CCM02536.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.11 CCM02536.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF938 PF06080.7 CCM02536.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Cript PF10235.4 CCM02537.1 - 0.012 15.9 1.7 0.012 15.9 0.0 1.7 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT SNF2_N PF00176.18 CCM02538.1 - 1.1e-09 37.5 0.5 0.00011 21.0 0.0 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-RING_5 PF14634.1 CCM02538.1 - 0.019 14.6 10.5 0.014 15.1 5.9 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCM02538.1 - 0.042 13.8 9.3 0.081 12.9 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCM02538.1 - 0.69 9.7 7.9 1.4 8.7 5.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 CCM02538.1 - 4.3 7.0 8.5 9.8 5.9 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_methylase PF00145.12 CCM02539.1 - 1.3e-13 50.8 0.0 2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Zw10 PF06248.8 CCM02541.1 - 6.1e-23 80.8 0.0 2e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 CCM02541.1 - 1e-07 31.4 0.0 2.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal DUF2450 PF10475.4 CCM02541.1 - 0.00033 19.6 0.3 0.0013 17.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Rep_fac_C PF08542.6 CCM02542.1 - 2.5e-18 65.8 0.0 6.9e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 CCM02542.1 - 3.5e-17 62.8 0.0 5.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCM02542.1 - 1.3e-16 60.6 0.1 1.3e-14 54.1 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CCM02542.1 - 6.2e-09 35.0 0.0 4e-07 29.1 0.0 2.2 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CCM02542.1 - 6.9e-07 29.2 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCM02542.1 - 3.2e-06 27.3 0.4 0.03 14.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 CCM02542.1 - 6.3e-06 25.2 0.0 9.3e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 CCM02542.1 - 7e-06 25.7 0.2 0.00091 18.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM02542.1 - 8e-06 25.5 0.0 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCM02542.1 - 2.8e-05 23.7 0.2 0.00031 20.3 0.0 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CCM02542.1 - 6e-05 22.2 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCM02542.1 - 7.2e-05 22.8 0.0 0.0015 18.5 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 CCM02542.1 - 8.6e-05 22.1 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 CCM02542.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCM02542.1 - 0.00075 19.2 0.1 0.0081 15.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CCM02542.1 - 0.0018 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DEAD PF00270.24 CCM02542.1 - 0.0022 17.4 0.1 0.048 13.1 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_24 PF13479.1 CCM02542.1 - 0.0031 17.1 0.1 0.0064 16.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CCM02542.1 - 0.0053 16.3 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 CCM02542.1 - 0.0062 15.9 0.1 0.035 13.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCM02542.1 - 0.0078 15.9 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 Archaeal ATPase ResIII PF04851.10 CCM02542.1 - 0.012 15.4 0.0 0.06 13.1 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 CCM02542.1 - 0.019 15.7 0.0 0.046 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Methyltransf_31 PF13847.1 CCM02542.1 - 0.037 13.6 0.1 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain T2SE PF00437.15 CCM02542.1 - 0.055 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 CCM02542.1 - 0.079 12.9 0.1 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 CCM02542.1 - 0.083 11.5 0.0 0.41 9.3 0.0 2.0 2 1 0 2 2 2 0 TIP49 C-terminus PIF1 PF05970.9 CCM02542.1 - 0.084 11.8 0.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.2 CCM02542.1 - 0.095 12.1 0.1 3.9 6.8 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 CCM02542.1 - 0.097 11.8 0.0 0.33 10.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 CCM02542.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 CCM02542.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ubiquitin PF00240.18 CCM02543.1 - 1.4e-34 117.2 0.7 1.4e-34 117.2 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 CCM02543.1 - 1.5e-26 91.9 1.6 3.2e-26 90.8 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CCM02543.1 - 7.5e-20 70.4 0.7 1.5e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCM02543.1 - 1.1e-05 25.5 0.4 5e-05 23.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCM02543.1 - 0.00021 21.0 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCM02543.1 - 0.00029 20.6 0.5 0.00064 19.5 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2207 PF09972.4 CCM02543.1 - 0.0041 15.7 0.8 0.0048 15.5 0.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2407 PF10302.4 CCM02543.1 - 0.0059 16.7 0.9 0.0079 16.3 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF971 PF06155.7 CCM02543.1 - 0.013 15.9 0.1 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) IBR PF01485.16 CCM02543.1 - 0.034 14.0 0.8 0.053 13.4 0.5 1.4 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 CCM02543.1 - 0.053 11.8 3.5 0.35 9.1 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Stig1 PF04885.8 CCM02543.1 - 0.065 13.4 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF2870 PF11069.3 CCM02543.1 - 0.13 12.3 1.5 0.14 12.1 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) SHR3_chaperone PF08229.6 CCM02546.1 - 1.2e-07 30.9 0.3 1.5e-07 30.6 0.2 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 RhoGAP PF00620.22 CCM02547.1 - 4.7e-41 139.9 0.0 8.9e-41 139.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 CCM02547.1 - 1.6e-12 47.5 0.0 3.2e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CCM02547.1 - 4e-08 33.4 0.0 1.1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 CCM02547.1 - 1.7e-06 27.8 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF3450 PF11932.3 CCM02547.1 - 0.043 13.0 0.5 0.082 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UAA PF08449.6 CCM02549.1 - 2e-70 237.1 10.4 2.4e-70 236.8 7.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CCM02549.1 - 5.7e-06 26.3 19.8 3.7e-05 23.7 1.7 3.2 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CCM02549.1 - 0.0018 17.9 5.5 0.0018 17.9 3.8 2.7 3 0 0 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 CCM02549.1 - 0.0082 16.3 1.7 0.0082 16.3 1.2 3.2 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF2569 PF10754.4 CCM02549.1 - 0.017 15.3 0.9 0.017 15.3 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) DUF914 PF06027.7 CCM02549.1 - 0.023 13.5 1.1 0.15 10.9 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Pkinase PF00069.20 CCM02550.1 - 2.1e-64 217.1 0.0 2.8e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02550.1 - 1.6e-36 125.6 0.0 2.4e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM02550.1 - 1.9e-08 33.6 0.0 3.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCM02550.1 - 0.0023 17.0 1.4 0.0076 15.3 0.1 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM02550.1 - 0.0034 17.1 0.7 0.0074 16.0 0.5 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CCM02550.1 - 0.014 14.7 0.5 0.065 12.5 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Vitellogenin_N PF01347.17 CCM02550.1 - 0.043 12.0 1.1 0.059 11.6 0.7 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Guanylate_kin PF00625.16 CCM02551.1 - 2.3e-67 225.9 0.0 2.6e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 CCM02551.1 - 1.9e-09 37.7 0.0 3.2e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CCM02551.1 - 1.3e-06 28.3 0.0 4.6e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCM02551.1 - 1.1e-05 25.6 0.0 0.00011 22.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCM02551.1 - 0.00017 22.4 0.1 0.003 18.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCM02551.1 - 0.00021 20.4 0.0 0.0003 19.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCM02551.1 - 0.00047 20.4 0.3 0.0057 16.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 CCM02551.1 - 0.00063 20.2 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 CCM02551.1 - 0.0008 19.3 0.0 0.0024 17.7 0.0 1.8 1 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CCM02551.1 - 0.0014 18.3 0.0 0.0036 16.9 0.0 1.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 CCM02551.1 - 0.0034 17.5 0.0 0.0082 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 CCM02551.1 - 0.0035 17.6 0.0 0.0038 17.5 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 CCM02551.1 - 0.0035 17.0 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 CCM02551.1 - 0.0038 17.1 0.0 0.0049 16.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CCM02551.1 - 0.0048 16.3 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 CCM02551.1 - 0.0051 16.2 0.1 0.015 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_28 PF13521.1 CCM02551.1 - 0.0093 15.9 0.0 0.056 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CCM02551.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.5 1 1 0 1 1 1 0 NTPase Rad17 PF03215.10 CCM02551.1 - 0.034 12.8 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CCM02551.1 - 0.054 13.2 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 CCM02551.1 - 0.065 12.1 0.0 0.87 8.4 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TRM PF02005.11 CCM02551.1 - 0.068 12.0 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase AAA PF00004.24 CCM02551.1 - 0.1 12.8 0.1 0.28 11.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 CCM02551.1 - 0.11 11.8 0.0 6 6.2 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.13 CCM02551.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 CCM02551.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF1640 PF07798.6 CCM02552.1 - 1.5e-52 178.2 10.6 1.6e-52 178.1 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) YfbU PF03887.9 CCM02552.1 - 0.026 14.1 0.6 0.046 13.2 0.1 1.6 1 1 1 2 2 2 0 YfbU domain COG5 PF10392.4 CCM02552.1 - 0.11 12.3 9.0 0.82 9.6 2.0 2.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF1822 PF08852.6 CCM02552.1 - 0.41 9.4 4.9 0.54 9.0 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) KIAA1430 PF13879.1 CCM02552.1 - 0.53 10.7 9.1 0.78 10.1 6.3 1.3 1 1 0 1 1 1 0 KIAA1430 homologue Phage_lysis PF03245.8 CCM02552.1 - 0.75 9.7 11.2 41 4.1 7.8 2.1 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein DUF4407 PF14362.1 CCM02552.1 - 0.77 8.6 7.1 1 8.2 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YscO PF07321.7 CCM02552.1 - 0.89 9.3 12.0 1.2 8.9 1.0 2.4 1 1 1 2 2 2 0 Type III secretion protein YscO TBPIP PF07106.8 CCM02552.1 - 1.2 8.7 11.2 0.94 9.0 6.5 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 CCM02552.1 - 1.6 7.0 9.6 2 6.7 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HALZ PF02183.13 CCM02552.1 - 1.8 8.3 6.9 2.1 8.0 0.8 3.5 2 2 1 3 3 3 0 Homeobox associated leucine zipper DUF2317 PF10079.4 CCM02552.1 - 2.6 6.5 9.6 4.6 5.7 6.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Baculo_PEP_C PF04513.7 CCM02552.1 - 3.4 7.4 8.0 7.6 6.3 1.7 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 CCM02552.1 - 3.7 7.5 8.4 0.87 9.5 0.8 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 CCM02552.1 - 6.3 6.3 12.9 1.3 8.5 3.0 2.8 1 1 1 2 2 2 0 Septum formation initiator Mak16 PF04874.9 CCM02553.1 - 7.2e-19 67.7 7.9 7.2e-19 67.7 5.5 3.4 1 1 2 3 3 3 2 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 CCM02553.1 - 2.5e-11 43.9 0.0 5.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L28e protein family Nop14 PF04147.7 CCM02553.1 - 0.0022 15.9 14.7 0.0024 15.8 10.2 1.2 1 0 0 1 1 1 1 Nop14-like family TFIIF_alpha PF05793.7 CCM02553.1 - 0.01 14.2 21.5 0.015 13.7 14.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 CCM02553.1 - 0.61 8.0 12.8 0.98 7.3 8.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CCM02553.1 - 6.4 5.1 18.7 7.6 4.8 13.0 1.1 1 0 0 1 1 1 0 Daxx Family FA_hydroxylase PF04116.8 CCM02554.1 - 1.2e-19 70.7 14.7 6.7e-19 68.3 4.5 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD-3 PF09765.4 CCM02555.1 - 0.016 14.5 1.4 0.019 14.2 1.0 1.0 1 0 0 1 1 1 0 WD-repeat region DASH_Hsk3 PF08227.6 CCM02555.1 - 1.4 9.1 6.1 3.8 7.7 4.3 1.8 1 1 0 1 1 1 0 DASH complex subunit Hsk3 like Kei1 PF08552.6 CCM02557.1 - 1.8e-38 132.1 3.1 2.5e-38 131.6 2.2 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 CCM02557.1 - 0.00074 19.4 3.1 0.0018 18.1 2.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4199) FixQ PF05545.6 CCM02557.1 - 0.049 13.2 0.4 0.049 13.2 0.3 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ IF4E PF01652.13 CCM02558.1 - 7.5e-46 155.6 0.0 1.1e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPT PF03151.11 CCM02559.1 - 3.6e-31 107.8 7.5 3.6e-31 107.8 5.2 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CCM02559.1 - 7e-16 58.0 20.4 9.3e-16 57.6 14.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CCM02559.1 - 5.3e-10 39.4 34.3 2.4e-08 34.0 8.3 3.6 2 1 1 3 3 3 2 EamA-like transporter family Sds3 PF08598.6 CCM02561.1 - 2.6e-06 27.1 3.7 2.6e-06 27.1 2.6 2.0 1 1 1 2 2 2 1 Sds3-like Smr PF01713.16 CCM02562.1 - 3.6e-11 43.1 0.0 1.1e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 CCM02562.1 - 0.031 14.2 4.3 0.085 12.8 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) SIR2 PF02146.12 CCM02564.1 - 1.1e-57 194.5 0.0 2.8e-57 193.3 0.0 1.7 2 0 0 2 2 2 1 Sir2 family DUF592 PF04574.8 CCM02564.1 - 0.00044 19.8 0.1 0.0046 16.5 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 CCM02564.1 - 0.048 13.4 0.6 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain RRM_1 PF00076.17 CCM02567.1 - 5e-15 54.8 0.0 9.1e-15 54.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chromo PF00385.19 CCM02567.1 - 2.5e-12 46.2 1.1 6.2e-12 44.9 0.1 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RRM_6 PF14259.1 CCM02567.1 - 2.7e-12 46.4 0.0 5.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Chromo_shadow PF01393.14 CCM02567.1 - 2.6e-09 36.7 0.0 4e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain RRM_5 PF13893.1 CCM02567.1 - 1.3e-07 31.3 0.0 2.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCM02567.1 - 0.016 15.0 0.2 0.059 13.2 0.0 2.1 1 1 1 2 2 2 0 RNA binding motif DUF3846 PF12957.2 CCM02568.1 - 0.05 13.3 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) ECR1_N PF14382.1 CCM02569.1 - 2.4e-15 55.5 0.0 4.3e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CCM02569.1 - 0.00015 21.6 0.0 0.00043 20.1 0.0 1.8 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Bclt PF15318.1 CCM02570.1 - 0.018 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis CAP_N PF01213.14 CCM02570.1 - 0.037 13.3 1.8 0.062 12.5 1.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_60s PF00428.14 CCM02570.1 - 0.14 12.6 3.8 0.21 12.0 2.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.13 CCM02570.1 - 0.42 9.7 3.5 0.62 9.1 2.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region zf-TFIIIC PF12660.2 CCM02571.1 - 1.8e-23 82.2 0.2 7.6e-23 80.2 0.2 2.1 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex FliT PF05400.8 CCM02572.1 - 0.025 14.9 2.5 0.037 14.4 1.8 1.3 1 0 0 1 1 1 0 Flagellar protein FliT CPSase_sm_chain PF00988.17 CCM02572.1 - 0.085 12.3 0.0 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain DUF2762 PF10960.3 CCM02572.1 - 0.11 12.2 6.2 0.44 10.2 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) UNC119_bdg PF15435.1 CCM02573.1 - 0.055 12.8 0.2 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue DUF2015 PF09435.5 CCM02574.1 - 3.2e-34 117.4 0.0 3.5e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF3325 PF11804.3 CCM02574.1 - 0.095 12.6 0.9 0.13 12.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) RED_N PF07808.8 CCM02575.1 - 1.5e-14 53.8 2.1 1.5e-14 53.8 1.5 2.2 2 1 0 2 2 2 1 RED-like protein N-terminal region KCl_Cotrans_1 PF03522.10 CCM02575.1 - 3.7 7.1 6.4 1.7 8.1 0.0 2.8 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) MBOAT PF03062.14 CCM02576.1 - 1.4e-24 86.8 17.6 7.2e-24 84.4 12.2 2.2 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DLH PF01738.13 CCM02577.1 - 5.5e-22 78.1 0.0 7e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family MMgT PF10270.4 CCM02577.1 - 5.2e-13 49.3 0.1 1.5e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Membrane magnesium transporter Abhydrolase_5 PF12695.2 CCM02577.1 - 8.5e-06 25.5 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM02577.1 - 0.002 18.0 0.1 0.14 12.0 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 CCM02578.1 - 1.6e-24 86.4 0.0 1.8e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCM02578.1 - 1.8e-06 27.8 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM02578.1 - 0.0074 16.1 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF383 PF04063.9 CCM02579.1 - 3.7e-56 189.7 0.0 7.5e-56 188.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CCM02579.1 - 1.9e-16 59.3 0.5 4.4e-16 58.1 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.4 CCM02579.1 - 0.011 13.9 0.2 0.06 11.5 0.0 2.0 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Spt20 PF12090.3 CCM02580.1 - 1.7e-21 76.3 0.1 2.7e-20 72.4 0.0 2.5 1 1 0 1 1 1 1 Spt20 family GATA PF00320.22 CCM02581.1 - 1.1e-13 50.2 3.2 1.9e-13 49.4 2.2 1.4 1 0 0 1 1 1 1 GATA zinc finger RR_TM4-6 PF06459.7 CCM02581.1 - 4.7 7.0 5.5 7.3 6.3 3.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DEAD PF00270.24 CCM02583.1 - 9.3e-44 148.8 0.0 4.7e-43 146.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM02583.1 - 7.2e-27 93.0 0.0 1.8e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM02583.1 - 0.0033 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S28e PF01200.13 CCM02583.1 - 0.095 12.4 0.1 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S28e TPR_11 PF13414.1 CCM02584.1 - 1.5e-10 40.5 0.3 1.4e-07 31.0 0.0 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCM02584.1 - 5.7e-06 25.8 0.4 0.0097 15.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCM02584.1 - 8.3e-05 22.0 0.8 0.21 11.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM02584.1 - 0.00011 22.0 0.3 0.022 14.6 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM02584.1 - 0.0089 16.6 0.9 0.14 12.8 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCM02584.1 - 0.055 13.8 0.2 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2183 PF09949.4 CCM02585.1 - 3.9e-25 87.7 0.0 7.5e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DLH PF01738.13 CCM02586.1 - 2.5e-22 79.2 0.0 2.9e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCM02586.1 - 1.6e-07 31.1 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM02586.1 - 0.00045 20.1 0.3 0.36 10.6 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family ADH_zinc_N PF00107.21 CCM02587.1 - 4.2e-32 110.4 0.5 6e-32 109.9 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM02587.1 - 2e-13 51.3 0.0 3.9e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM02587.1 - 1.4e-07 31.2 0.0 5.7e-07 29.2 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 CCM02587.1 - 0.017 15.1 0.6 0.027 14.4 0.4 1.3 1 0 0 1 1 1 0 NADH(P)-binding DLH PF01738.13 CCM02588.1 - 3.1e-19 69.1 0.0 3.8e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCM02588.1 - 1.6e-06 27.9 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM02588.1 - 0.0048 16.7 0.1 0.06 13.2 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Arginosuc_synth PF00764.14 CCM02589.1 - 3.2e-116 388.5 0.0 1.7e-77 261.1 0.0 2.0 1 1 1 2 2 2 2 Arginosuccinate synthase QueC PF06508.8 CCM02589.1 - 6.8e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 CCM02589.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 CCM02589.1 - 0.027 13.0 0.0 0.051 12.1 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase RTC4 PF14474.1 CCM02591.1 - 1.7e-21 76.4 0.0 4.4e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain PTS_2-RNA PF01885.11 CCM02592.1 - 2.4e-54 183.4 0.0 4.3e-31 107.6 0.0 2.0 2 0 0 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family NOA36 PF06524.7 CCM02593.1 - 0.025 13.8 1.5 0.051 12.8 1.0 1.5 1 0 0 1 1 1 0 NOA36 protein Macoilin PF09726.4 CCM02593.1 - 2.4 6.3 13.5 3.3 5.8 9.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 CCM02593.1 - 2.9 6.7 4.0 4 6.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nucleoplasmin PF03066.10 CCM02593.1 - 6.4 6.2 8.3 21 4.6 5.8 1.8 1 0 0 1 1 1 0 Nucleoplasmin HD_3 PF13023.1 CCM02595.1 - 6.2e-13 48.8 2.3 1.1e-12 48.0 1.7 1.4 1 1 0 1 1 1 1 HD domain DUF4286 PF14114.1 CCM02595.1 - 0.025 14.8 0.3 0.053 13.8 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4286) AICARFT_IMPCHas PF01808.13 CCM02596.1 - 1.5e-109 365.8 0.0 2e-109 365.5 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CCM02596.1 - 6.2e-25 86.9 0.0 1.1e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Glutaredoxin PF00462.19 CCM02598.1 - 9.5e-17 60.7 0.0 1.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin DNA_pol_B PF00136.16 CCM02599.1 - 1.9e-113 379.7 0.0 2.7e-113 379.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CCM02599.1 - 1.2e-56 191.0 0.0 2.1e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CCM02599.1 - 2.7e-27 95.4 0.0 4.3e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 CCM02599.1 - 8.7e-13 47.8 9.4 1e-12 47.6 5.4 2.2 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Flavin_Reduct PF01613.13 CCM02600.1 - 1.8e-29 102.6 0.3 2.4e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 Flavin reductase like domain HTH_DeoR PF08220.7 CCM02600.1 - 0.2 11.2 0.7 0.42 10.1 0.2 1.7 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain MFS_1 PF07690.11 CCM02601.1 - 5e-34 117.5 36.6 5e-34 117.5 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCM02601.1 - 5.6e-05 21.4 4.3 9.1e-05 20.7 3.0 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF4526 PF15029.1 CCM02601.1 - 0.19 11.2 0.5 0.53 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) RabGAP-TBC PF00566.13 CCM02603.1 - 2e-37 128.7 0.0 3.3e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 CCM02603.1 - 0.0003 20.4 2.5 0.0018 18.0 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CCM02603.1 - 0.00043 19.3 0.1 0.0013 17.9 0.1 1.9 1 0 0 1 1 1 1 EF hand GRAM PF02893.15 CCM02603.1 - 0.0014 18.0 0.0 0.0037 16.7 0.0 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.1 CCM02603.1 - 0.0023 18.0 1.0 0.0071 16.4 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CCM02603.1 - 0.031 13.6 0.4 0.12 11.7 0.1 2.2 2 0 0 2 2 2 0 EF hand WD40 PF00400.27 CCM02604.1 - 1.3e-45 151.6 19.9 5.5e-13 48.2 0.1 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CCM02604.1 - 7.7e-05 22.4 0.1 0.0058 16.3 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCM02604.1 - 0.00018 19.8 1.8 0.0088 14.2 0.6 3.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Kelch_6 PF13964.1 CCM02604.1 - 0.022 14.9 0.2 1.5 9.1 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Nucleoporin_N PF08801.6 CCM02604.1 - 0.13 11.0 4.5 0.57 8.8 0.5 2.4 1 1 0 2 2 2 0 Nup133 N terminal like CAP_N PF01213.14 CCM02604.1 - 0.91 8.7 5.1 1.3 8.2 3.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 CCM02604.1 - 1.2 8.4 7.4 1.7 7.9 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DIOX_N PF14226.1 CCM02605.1 - 9.3e-16 58.4 0.0 1.7e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM02605.1 - 9.5e-14 51.4 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SAICAR_synt PF01259.13 CCM02606.1 - 3.8e-83 278.3 0.0 5e-83 278.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase DNA_ligase_A_M PF01068.16 CCM02607.1 - 2.2e-23 82.6 0.0 4.7e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCM02607.1 - 9.1e-15 54.9 0.0 1.8e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus WD40 PF00400.27 CCM02608.1 - 2.3e-85 277.7 35.3 5.9e-13 48.1 0.5 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 CCM02608.1 - 6.8e-09 35.6 0.2 1.2e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CCM02608.1 - 8.7e-09 34.0 11.5 0.0085 14.2 0.0 4.9 3 2 3 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCM02608.1 - 0.0016 17.2 1.5 0.82 8.3 0.0 3.2 3 2 1 4 4 4 2 Nup133 N terminal like IKI3 PF04762.7 CCM02608.1 - 0.075 10.8 0.1 0.14 9.9 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Pirin PF02678.11 CCM02609.1 - 2.4e-26 91.6 0.5 3.7e-26 91.0 0.4 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 CCM02609.1 - 3.9e-07 29.4 1.7 2.6e-05 23.6 0.5 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 CCM02609.1 - 0.038 13.3 0.2 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) MMR_HSR1 PF01926.18 CCM02610.1 - 1.3e-14 54.1 0.0 1.8e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCM02610.1 - 2.1e-06 27.6 0.0 0.0031 17.3 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 CCM02610.1 - 0.00082 18.5 0.0 0.0013 17.9 0.0 1.4 1 1 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 CCM02610.1 - 0.001 18.3 0.1 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 CCM02610.1 - 0.0046 16.1 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCM02610.1 - 0.017 14.6 0.0 0.053 13.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CCM02610.1 - 0.019 14.6 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Septin PF00735.13 CCM02610.1 - 0.024 13.6 0.0 0.54 9.2 0.0 2.3 1 1 0 1 1 1 0 Septin NTPase_1 PF03266.10 CCM02610.1 - 0.055 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 NTPase Miro PF08477.8 CCM02610.1 - 0.057 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 CCM02610.1 - 0.1 12.7 0.1 0.58 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain YadA_anchor PF03895.10 CCM02611.1 - 0.049 13.6 4.6 1.5 8.8 0.1 3.0 4 0 0 4 4 4 0 YadA-like C-terminal region E1-E2_ATPase PF00122.15 CCM02613.1 - 1.1e-38 132.5 6.4 1.9e-38 131.7 4.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCM02613.1 - 3.8e-29 102.6 0.7 6.6e-29 101.8 0.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCM02613.1 - 2e-10 41.1 0.0 4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CCM02613.1 - 3.4e-08 33.4 0.1 1.1e-07 31.8 0.1 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 CCM02613.1 - 0.045 13.3 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MKT1_C PF12246.3 CCM02615.1 - 3.2e-60 203.1 0.0 4.9e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CCM02615.1 - 5.1e-26 90.8 0.0 9.7e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 CCM02615.1 - 7.8e-12 45.1 0.0 1.7e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCM02615.1 - 1.6e-08 34.7 0.0 3.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DUF2757 PF10955.3 CCM02615.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) DUF4463 PF14703.1 CCM02615.1 - 0.073 13.5 0.1 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) VPS9 PF02204.13 CCM02617.1 - 3e-19 68.9 0.0 6.7e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain CENP-B_dimeris PF09026.5 CCM02617.1 - 3.3 8.0 22.3 1.2 9.3 2.4 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Opi1 PF08618.5 CCM02619.1 - 2.3e-60 204.7 19.4 6.3e-52 176.9 5.0 3.8 2 1 1 3 3 3 2 Transcription factor Opi1 Perilipin PF03036.11 CCM02619.1 - 0.0013 17.6 0.9 0.0033 16.3 0.0 2.0 3 0 0 3 3 3 1 Perilipin family REF PF05755.7 CCM02619.1 - 0.057 13.1 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) Corona_nucleoca PF00937.13 CCM02619.1 - 0.08 11.8 0.2 0.15 11.0 0.2 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein GATA PF00320.22 CCM02620.1 - 1.6e-16 59.3 3.5 3.4e-16 58.2 2.4 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CCM02620.1 - 0.12 11.7 1.1 0.24 10.7 0.7 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding HAUS6_N PF14661.1 CCM02621.1 - 4.5e-10 39.3 0.0 3.6e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 6 N-terminus VCBS PF13517.1 CCM02623.1 - 3.6e-14 52.8 20.6 3e-05 24.2 0.7 5.3 1 1 4 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3471 PF11954.3 CCM02623.1 - 5.1e-05 23.0 0.0 21 5.0 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF3471) EF-hand_5 PF13202.1 CCM02623.1 - 0.00018 20.6 0.2 3.8 7.0 0.0 4.5 4 0 0 4 4 4 2 EF hand DIPSY PF11763.3 CCM02623.1 - 0.02 14.6 0.0 26 4.5 0.0 4.4 2 1 3 6 6 6 0 Cell-wall adhesin ligand-binding C-terminal Moricin PF06451.6 CCM02623.1 - 0.022 14.2 2.7 9.9 5.7 0.1 3.4 3 0 0 3 3 3 0 Moricin MORN_2 PF07661.8 CCM02623.1 - 0.048 13.6 0.0 57 4.2 0.0 4.0 4 0 0 4 4 4 0 MORN repeat variant GvpG PF05120.7 CCM02623.1 - 0.089 12.6 1.6 82 3.1 0.0 4.9 6 0 0 6 6 6 0 Gas vesicle protein G Peptidase_S49 PF01343.13 CCM02623.1 - 0.14 11.9 0.1 41 3.9 0.0 2.9 3 0 0 3 3 3 0 Peptidase family S49 EF-hand_6 PF13405.1 CCM02623.1 - 3.5 7.7 13.0 37 4.5 0.0 5.5 7 0 0 7 7 7 0 EF-hand domain EF-hand_1 PF00036.27 CCM02623.1 - 6.2 6.3 6.6 71 3.0 0.0 4.4 5 0 0 5 5 5 0 EF hand UQ_con PF00179.21 CCM02624.1 - 1.8e-24 85.7 0.3 4.1e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme MOZART1 PF12554.3 CCM02624.1 - 1e-23 82.5 0.6 1.7e-23 81.7 0.4 1.4 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated PAP1 PF08601.5 CCM02624.1 - 0.068 12.8 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 DOPA_dioxygen PF08883.6 CCM02625.1 - 7.1e-30 103.1 0.1 8.9e-30 102.8 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PALP PF00291.20 CCM02626.1 - 4.5e-30 104.9 0.3 5.4e-30 104.6 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1275 PF06912.6 CCM02627.1 - 3.3e-09 36.2 26.9 8e-08 31.7 18.6 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) GHMP_kinases_C PF08544.8 CCM02627.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal Vps55 PF04133.9 CCM02627.1 - 2.2 8.0 9.2 3.4 7.4 1.6 3.4 2 1 1 3 3 3 0 Vacuolar protein sorting 55 DUF4149 PF13664.1 CCM02627.1 - 3.6 7.6 9.7 8.6 6.4 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) VID27 PF08553.5 CCM02628.1 - 0.034 12.3 0.4 0.047 11.9 0.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein MFS_1 PF07690.11 CCM02629.1 - 2.3e-33 115.3 50.8 2.3e-33 115.3 35.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCM02629.1 - 5.6e-18 64.4 16.2 7.3e-18 64.0 10.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCM02629.1 - 7.4e-14 51.1 24.7 9e-14 50.8 7.3 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter SRF-TF PF00319.13 CCM02631.1 - 1e-11 43.8 0.0 1.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) OrfB_Zn_ribbon PF07282.6 CCM02632.1 - 0.15 11.7 0.2 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain VPS28 PF03997.7 CCM02633.1 - 1.3e-44 152.0 0.0 7e-36 123.6 0.0 3.0 1 1 1 2 2 2 2 VPS28 protein Cu-oxidase PF00394.17 CCM02634.1 - 1e-39 135.9 0.0 5.2e-38 130.4 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCM02634.1 - 7.3e-36 122.4 3.5 5.6e-35 119.6 0.2 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCM02634.1 - 6.7e-33 113.1 6.1 4.3e-31 107.2 0.0 3.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 CCM02635.1 - 3.7e-41 140.6 0.0 8.6e-38 129.7 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCM02635.1 - 5.5e-37 126.0 0.5 3.2e-25 88.1 0.1 4.2 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCM02635.1 - 6.6e-34 116.3 3.5 4.7e-32 110.3 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase GLTP PF08718.6 CCM02636.1 - 2.1e-08 34.3 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF4451 PF14616.1 CCM02636.1 - 6.9e-08 32.2 9.2 0.25 11.0 0.0 4.3 3 1 1 4 4 4 3 Domain of unknown function (DUF4451) zf-ribbon_3 PF13248.1 CCM02636.1 - 0.11 11.7 3.2 12 5.3 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Ecl1 PF12855.2 CCM02636.1 - 0.34 10.2 5.6 1.6 8.0 0.1 2.6 2 0 0 2 2 2 0 Life-span regulatory factor HypA PF01155.14 CCM02636.1 - 6.4 6.4 7.2 21 4.8 0.2 3.2 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family Pkinase PF00069.20 CCM02637.1 - 1.8e-59 200.9 0.0 2.2e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02637.1 - 3.3e-18 65.7 0.0 4.1e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM02637.1 - 5.4e-09 36.1 0.0 1.6e-05 24.7 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CCM02637.1 - 0.00055 19.3 0.1 0.001 18.4 0.1 1.4 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CCM02637.1 - 0.00089 18.8 0.0 0.0017 17.9 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase MA3 PF02847.12 CCM02637.1 - 0.0024 17.5 0.1 0.005 16.5 0.1 1.4 1 0 0 1 1 1 1 MA3 domain ABC1 PF03109.11 CCM02637.1 - 0.044 13.7 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC1 family DUF1679 PF07914.6 CCM02637.1 - 0.07 11.7 0.0 0.84 8.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) Kinase-like PF14531.1 CCM02637.1 - 0.092 11.6 0.0 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.4 CCM02637.1 - 0.15 11.4 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Fungal_trans PF04082.13 CCM02638.1 - 1e-13 50.7 0.0 1.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 CCM02639.1 - 5.1e-27 94.3 0.1 8.6e-27 93.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSBP1 PF06825.7 CCM02639.1 - 0.083 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 CCM02639.1 - 0.086 12.2 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Phosphoprotein PF00922.12 CCM02640.1 - 3.5 6.7 8.4 4.6 6.3 5.8 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Amidase PF01425.16 CCM02641.1 - 6.6e-105 351.5 1.4 8.8e-105 351.0 1.0 1.2 1 0 0 1 1 1 1 Amidase WD40 PF00400.27 CCM02642.1 - 4.9e-31 105.4 1.6 1.7e-09 37.2 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCM02642.1 - 0.0096 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.3 CCM02642.1 - 0.016 13.3 0.9 0.048 11.8 0.0 2.1 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCM02642.1 - 0.027 12.7 1.7 0.17 10.1 0.0 2.5 3 1 1 4 4 4 0 Cytochrome D1 heme domain RNA_pol_Rpc4 PF05132.9 CCM02642.1 - 0.13 12.1 0.1 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1604 PF07713.8 CCM02643.1 - 1.1e-35 121.2 0.7 1.1e-35 121.2 0.5 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 CCM02643.1 - 1.2e-06 28.2 0.2 3.8e-06 26.5 0.1 2.0 1 0 0 1 1 1 1 G-patch domain AA_permease PF00324.16 CCM02644.1 - 3.2e-110 368.7 36.5 9.9e-110 367.1 25.3 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCM02644.1 - 1.4e-34 119.3 36.0 2.3e-34 118.6 25.0 1.3 1 1 0 1 1 1 1 Amino acid permease DUF3487 PF11990.3 CCM02644.1 - 7.9 5.9 7.3 0.5 9.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) RhoGEF PF00621.15 CCM02646.1 - 4.2e-71 238.5 2.5 8.4e-35 120.2 0.1 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 CCM02646.1 - 1.4e-62 211.6 0.0 2.2e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CCM02646.1 - 5.9e-19 68.3 0.0 1.3e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CCM02646.1 - 7e-07 29.4 0.0 3.6e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 PH domain DEP PF00610.16 CCM02646.1 - 0.00028 20.5 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Methyltransf_23 PF13489.1 CCM02647.1 - 1.2e-12 47.8 0.0 2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM02647.1 - 2.4e-10 40.7 0.0 6.5e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM02647.1 - 1.3e-08 35.3 0.0 2.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM02647.1 - 1.7e-08 34.1 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM02647.1 - 2.8e-08 34.0 0.0 5.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM02647.1 - 4.3e-08 33.5 0.0 1.7e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM02647.1 - 0.00018 21.4 0.0 0.00061 19.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.3 CCM02647.1 - 0.0024 16.6 0.0 0.0047 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) MTS PF05175.9 CCM02647.1 - 0.014 14.7 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 CCM02647.1 - 0.15 12.8 0.0 0.32 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CNH PF00780.17 CCM02649.1 - 2.4e-43 148.5 0.0 3.3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CCM02649.1 - 6.4e-19 68.2 0.0 1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CCM02649.1 - 0.0011 19.0 0.0 0.0036 17.4 0.0 1.9 2 0 0 2 2 2 1 PH domain Lipase_3 PF01764.20 CCM02650.1 - 3.3e-23 81.8 0.0 5.3e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CCM02650.1 - 8.1e-05 22.6 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM02650.1 - 0.0049 16.6 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM02650.1 - 0.0063 16.1 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.6 CCM02650.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF915 PF06028.6 CCM02650.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CCM02651.1 - 6.4e-22 77.6 0.0 9.1e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CCM02651.1 - 0.0041 17.0 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CCM02651.1 - 0.032 13.6 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.2 CCM02651.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 CCM02651.1 - 0.042 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_8 PF06259.7 CCM02651.1 - 0.049 13.1 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 CCM02651.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CAP_GLY PF01302.20 CCM02652.1 - 8e-27 92.7 1.5 1.5e-26 91.8 1.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CCM02652.1 - 1.7e-23 82.6 0.1 2.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 CCM02652.1 - 0.0051 16.1 0.0 0.36 10.2 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin family AAA PF00004.24 CCM02653.1 - 3e-97 321.9 0.0 1.5e-47 161.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCM02653.1 - 2.6e-22 78.5 0.3 4.3e-21 74.6 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 CCM02653.1 - 9.7e-14 50.9 0.0 8.7e-06 24.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CCM02653.1 - 1.6e-13 50.9 0.0 1.3e-07 31.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CCM02653.1 - 5.9e-13 48.9 0.0 1.5e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCM02653.1 - 1.5e-12 47.4 0.5 5.1e-06 26.2 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCM02653.1 - 1.9e-12 48.0 0.0 0.0003 21.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CCM02653.1 - 1.1e-11 45.0 0.2 0.0015 18.6 0.0 4.3 3 2 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 CCM02653.1 - 4.8e-11 42.1 0.0 1.3e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 CCM02653.1 - 1.4e-10 41.4 0.0 0.0012 18.8 0.0 3.3 2 2 1 3 3 2 2 AAA ATPase domain TIP49 PF06068.8 CCM02653.1 - 3.3e-09 35.9 0.0 0.001 17.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 CCM02653.1 - 3.7e-08 32.9 2.1 0.017 14.5 0.0 3.6 2 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 CCM02653.1 - 4.3e-08 33.1 0.0 0.0037 17.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 CCM02653.1 - 4.9e-08 32.3 0.0 0.01 14.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CCM02653.1 - 6.8e-08 32.1 0.0 0.0043 16.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCM02653.1 - 2.9e-07 29.8 0.3 0.024 13.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CCM02653.1 - 3.5e-07 29.5 0.6 0.16 11.0 0.0 3.4 2 1 1 3 3 3 2 KaiC RNA_helicase PF00910.17 CCM02653.1 - 4.2e-07 30.1 0.0 0.018 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 CCM02653.1 - 5.4e-07 29.2 1.9 0.018 14.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Vps4_C PF09336.5 CCM02653.1 - 1.4e-06 28.1 0.1 1.8e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.1 CCM02653.1 - 2.5e-06 27.8 0.5 0.037 14.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.12 CCM02653.1 - 3.1e-06 26.2 0.1 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CCM02653.1 - 3.2e-06 26.8 0.1 0.065 12.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 CCM02653.1 - 4.7e-06 26.5 0.0 0.0036 17.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 CCM02653.1 - 5.2e-06 26.5 0.0 0.085 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 CCM02653.1 - 8.5e-06 24.8 0.0 0.0063 15.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CCM02653.1 - 9e-06 25.5 0.0 0.77 9.4 0.1 3.9 3 1 1 4 4 4 2 Archaeal ATPase Sigma54_activat PF00158.21 CCM02653.1 - 1.1e-05 24.9 0.0 0.31 10.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CCM02653.1 - 1.3e-05 25.2 0.0 0.33 10.9 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 CCM02653.1 - 1.7e-05 25.1 0.0 0.054 13.7 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 CCM02653.1 - 4.1e-05 23.3 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein PhoH PF02562.11 CCM02653.1 - 7.2e-05 22.1 0.3 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 CCM02653.1 - 0.00014 21.4 0.0 0.52 9.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CCM02653.1 - 0.00019 21.0 0.1 0.75 9.3 0.0 3.1 3 1 0 3 3 2 2 AAA domain NACHT PF05729.7 CCM02653.1 - 0.0002 21.0 0.1 0.56 9.8 0.0 3.4 4 0 0 4 4 3 1 NACHT domain DUF2075 PF09848.4 CCM02653.1 - 0.00052 19.0 0.0 0.75 8.7 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 CCM02653.1 - 0.00059 18.7 0.0 0.15 10.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 CCM02653.1 - 0.0015 18.1 0.0 2.9 7.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 CCM02653.1 - 0.0047 15.8 0.0 0.35 9.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 CCM02653.1 - 0.0058 16.1 0.0 0.67 9.4 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 CCM02653.1 - 0.0074 15.4 0.1 2 7.5 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase UFD1 PF03152.9 CCM02653.1 - 0.017 14.2 0.0 0.044 12.9 0.0 1.6 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 NTPase_1 PF03266.10 CCM02653.1 - 0.019 14.6 0.4 5.6 6.6 0.0 3.4 3 0 0 3 3 3 0 NTPase UPF0079 PF02367.12 CCM02653.1 - 0.036 13.7 0.1 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 CCM02653.1 - 0.041 12.8 0.0 0.95 8.3 0.0 2.7 2 2 1 3 3 3 0 KAP family P-loop domain Zot PF05707.7 CCM02653.1 - 0.059 12.8 0.2 13 5.1 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.17 CCM02653.1 - 0.072 12.9 0.0 7.1 6.4 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 CCM02653.1 - 0.12 11.5 0.0 8.4 5.5 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Molydop_binding PF01568.16 CCM02653.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain DEAD PF00270.24 CCM02653.1 - 0.17 11.3 0.4 62 3.0 0.0 3.3 2 1 1 3 3 3 0 DEAD/DEAH box helicase Torsin PF06309.6 CCM02653.1 - 0.23 11.3 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Torsin PPV_E1_C PF00519.12 CCM02653.1 - 0.42 9.1 0.0 6.4 5.2 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase DAGAT PF03982.8 CCM02654.1 - 1.7e-99 332.2 0.0 2.3e-99 331.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Cellulase PF00150.13 CCM02655.1 - 8.6e-14 51.4 0.3 2.1e-13 50.1 0.2 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NAD_binding_10 PF13460.1 CCM02656.1 - 6.4e-09 36.0 0.0 9.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM02656.1 - 1.9e-05 24.2 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCM02656.1 - 6.8e-05 23.1 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 CCM02656.1 - 0.0064 15.4 0.0 0.58 9.0 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein AAA_28 PF13521.1 CCM02656.1 - 0.035 14.0 0.2 0.096 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain Saccharop_dh PF03435.13 CCM02656.1 - 0.065 12.2 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 CCM02656.1 - 0.081 12.8 0.5 1.1 9.1 0.3 2.1 1 1 0 1 1 1 0 short chain dehydrogenase 4HBT_2 PF13279.1 CCM02657.1 - 7.3e-14 52.2 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 CCM02657.1 - 0.00037 20.5 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 CCM02657.1 - 0.0028 16.6 0.1 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase RuvA_C PF07499.8 CCM02657.1 - 0.018 15.2 0.0 0.052 13.7 0.0 1.7 2 0 0 2 2 2 0 RuvA, C-terminal domain AA_permease PF00324.16 CCM02658.1 - 8.4e-120 400.3 34.9 9.5e-120 400.1 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCM02658.1 - 3.2e-37 128.1 38.8 3.9e-37 127.8 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease Tnp_P_element PF12017.3 CCM02658.1 - 0.015 14.5 0.1 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Transposase protein Ytp1 PF10355.4 CCM02659.1 - 1.7e-70 237.3 7.8 2.5e-70 236.8 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CCM02659.1 - 5.6e-25 86.9 1.1 5.6e-25 86.9 0.7 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF2607 PF10795.4 CCM02659.1 - 0.047 13.5 0.6 0.12 12.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) HMG_box PF00505.14 CCM02660.1 - 1.6e-13 50.7 4.4 3.1e-13 49.7 3.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM02660.1 - 0.017 15.4 2.6 0.02 15.2 1.4 1.5 1 1 0 1 1 1 0 HMG-box domain UBX PF00789.15 CCM02662.1 - 1.5e-11 44.1 0.2 4.4e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 UBX domain zf-C2H2_2 PF12756.2 CCM02662.1 - 0.011 15.8 0.8 0.028 14.5 0.2 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) RWD PF05773.17 CCM02662.1 - 0.056 13.3 0.3 0.11 12.4 0.2 1.9 1 1 0 1 1 1 0 RWD domain CpXC PF14353.1 CCM02662.1 - 0.9 9.5 6.3 1.5 8.7 3.9 1.7 1 1 0 1 1 1 0 CpXC protein Ycf1 PF05758.7 CCM02662.1 - 1.2 6.7 5.2 1.2 6.7 3.6 1.1 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 CCM02662.1 - 6.9 4.8 19.1 9.2 4.4 13.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Uds1 PF15456.1 CCM02663.1 - 0.00011 22.1 13.3 0.00033 20.6 3.8 2.7 1 1 1 2 2 2 2 Up-regulated During Septation STT3 PF02516.9 CCM02664.1 - 1.4e-134 449.7 37.0 4.9e-133 444.6 25.7 2.2 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 CCM02664.1 - 0.00062 19.7 12.6 0.00062 19.7 8.7 3.7 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Thioredoxin PF00085.15 CCM02666.1 - 1.6e-09 37.3 0.0 6.7e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Ran_BP1 PF00638.13 CCM02667.1 - 2.2e-05 24.4 0.1 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Dicty_REP PF05086.7 CCM02667.1 - 3.2 5.3 4.1 4.3 4.9 2.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNase_H2_suC PF08615.6 CCM02669.1 - 2.3e-22 79.2 0.0 5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) ESCRT-II PF05871.7 CCM02671.1 - 2.4e-32 111.7 0.0 3.2e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit MFS_1 PF07690.11 CCM02672.1 - 1.6e-15 56.6 46.4 1.2e-09 37.3 15.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily HALZ PF02183.13 CCM02673.1 - 0.14 11.8 0.8 0.31 10.7 0.4 1.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper CxxCxxCC PF03692.10 CCM02674.1 - 0.04 14.4 0.7 0.04 14.4 0.5 2.3 2 1 0 2 2 2 0 Putative zinc- or iron-chelating domain Uds1 PF15456.1 CCM02674.1 - 0.09 12.7 1.1 0.2 11.6 0.8 1.5 1 0 0 1 1 1 0 Up-regulated During Septation DUF4140 PF13600.1 CCM02674.1 - 0.11 12.9 0.1 0.6 10.5 0.0 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Metal_resist PF13801.1 CCM02675.1 - 0.0053 16.7 3.4 0.0053 16.7 2.4 3.3 2 1 0 3 3 3 1 Heavy-metal resistance Fib_alpha PF08702.5 CCM02675.1 - 0.023 14.8 17.1 2 8.5 1.9 3.9 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 CCM02675.1 - 0.069 12.9 33.6 0.13 12.0 0.1 4.2 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF4047 PF13256.1 CCM02675.1 - 0.072 13.0 10.0 0.73 9.8 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) HALZ PF02183.13 CCM02675.1 - 1 9.1 13.5 12 5.7 0.9 5.0 4 1 0 4 4 4 0 Homeobox associated leucine zipper NPV_P10 PF05531.7 CCM02675.1 - 1.2 9.4 6.9 5.7 7.2 1.3 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MGC-24 PF05283.6 CCM02675.1 - 1.8 8.3 10.0 0.69 9.6 5.0 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Filament PF00038.16 CCM02675.1 - 4.3 6.7 34.9 15 4.9 0.2 3.1 2 1 0 2 2 2 0 Intermediate filament protein DUF948 PF06103.6 CCM02675.1 - 6.2 6.7 12.6 11 5.9 1.5 4.4 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 CCM02675.1 - 7.9 5.3 29.9 2.4 6.9 2.9 3.3 2 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 FMN_red PF03358.10 CCM02676.1 - 0.033 13.7 0.4 0.078 12.4 0.3 1.6 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Atg14 PF10186.4 CCM02676.1 - 0.057 12.3 13.9 0.11 11.4 9.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 CCM02676.1 - 0.12 11.3 5.8 0.2 10.6 4.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein BTV_NS2 PF04514.7 CCM02676.1 - 0.16 10.8 4.9 0.26 10.1 3.4 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Spc7 PF08317.6 CCM02676.1 - 0.16 10.6 9.1 0.27 9.8 6.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HTH_39 PF14090.1 CCM02676.1 - 0.68 9.4 3.8 4.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain DivIC PF04977.10 CCM02676.1 - 1 8.9 11.6 4 6.9 1.6 3.3 2 1 1 3 3 3 0 Septum formation initiator Fib_alpha PF08702.5 CCM02676.1 - 1.3 9.1 8.7 3 7.9 5.7 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Cut8_N PF14482.1 CCM02676.1 - 2.6 8.0 9.7 0.13 12.2 0.3 2.9 3 0 0 3 3 3 0 Cut8 proteasome-binding domain NMO PF03060.10 CCM02677.1 - 2e-71 240.8 1.0 2.5e-71 240.5 0.7 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCM02677.1 - 0.00043 19.2 0.1 0.0087 14.9 0.1 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CCM02677.1 - 0.19 10.5 4.2 0.29 9.9 2.9 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PACT_coil_coil PF10495.4 CCM02679.1 - 4.8e-12 45.6 1.1 3.1e-11 43.0 0.2 3.0 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Laminin_II PF06009.7 CCM02679.1 - 0.0041 16.8 10.1 0.0041 16.8 7.0 9.6 5 3 6 11 11 11 4 Laminin Domain II Reo_sigmaC PF04582.7 CCM02679.1 - 0.0043 16.2 43.3 0.14 11.2 0.6 6.0 3 2 2 5 5 5 4 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 CCM02679.1 - 0.16 11.6 0.0 0.16 11.6 0.0 11.6 4 2 6 12 12 12 0 TPR/MLP1/MLP2-like protein PSCyt3 PF07627.6 CCM02679.1 - 0.24 11.2 0.0 0.24 11.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) CDP-OH_P_transf PF01066.16 CCM02680.1 - 6.5e-19 68.1 4.2 6.5e-19 68.1 2.9 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase p450 PF00067.17 CCM02682.1 - 2e-66 224.4 0.0 2.4e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF148 PF02520.12 CCM02682.1 - 0.12 12.1 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF1348 PF07080.6 CCM02683.1 - 2.2e-54 183.1 4.9 2.6e-54 182.9 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 CCM02683.1 - 6.7e-07 29.4 0.3 1.3e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 CCM02683.1 - 8.9e-05 22.8 1.1 0.00011 22.5 0.1 1.7 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.7 CCM02683.1 - 0.11 12.0 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase zf-C2H2_4 PF13894.1 CCM02684.1 - 0.31 11.4 4.6 0.73 10.3 3.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM02684.1 - 0.42 11.0 7.4 0.12 12.8 2.8 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type p450 PF00067.17 CCM02686.1 - 3.1e-54 184.2 0.0 8.6e-50 169.5 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 T2SF PF00482.18 CCM02686.1 - 0.018 14.9 1.4 0.31 10.9 0.7 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F COMPASS-Shg1 PF05205.7 CCM02688.1 - 0.089 13.0 3.9 0.16 12.2 2.7 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 p450 PF00067.17 CCM02690.1 - 5.6e-60 203.1 0.0 1.5e-59 201.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM02691.1 - 3.9e-61 206.9 0.0 1.5e-60 205.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 VPEP PF07589.6 CCM02691.1 - 0.27 11.1 4.2 6 6.9 0.0 2.6 2 0 0 2 2 2 0 PEP-CTERM motif Herpes_UL79 PF03049.9 CCM02692.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 UL79 family TMEM173 PF15009.1 CCM02694.1 - 1 8.0 7.9 0.027 13.2 0.7 1.8 2 0 0 2 2 2 0 Transmembrane protein 173 HTH_31 PF13560.1 CCM02695.1 - 8.6e-05 22.6 0.0 9.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 CCM02695.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.7 CCM02695.1 - 0.014 14.7 0.1 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 CCM02695.1 - 0.015 14.8 0.0 0.078 12.5 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain GcrA PF07750.6 CCM02695.1 - 0.018 15.2 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 GcrA cell cycle regulator Sigma70_r4 PF04545.11 CCM02695.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_19 PF12844.2 CCM02695.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.1 CCM02695.1 - 0.15 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF1348 PF07080.6 CCM02696.1 - 8.9e-30 103.3 1.2 1.1e-29 103.1 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 CCM02696.1 - 3e-05 24.3 0.5 3.9e-05 23.9 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 CCM02696.1 - 0.0014 18.1 0.1 0.0016 17.9 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.1 CCM02696.1 - 0.074 13.2 0.2 0.082 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) FMO-like PF00743.14 CCM02697.1 - 2.5e-21 75.4 0.3 4e-20 71.5 0.2 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCM02697.1 - 1.5e-14 54.5 0.0 2.8e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM02697.1 - 2.5e-10 39.7 0.1 3.9e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM02697.1 - 9.2e-08 32.2 0.0 6.6e-07 29.4 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM02697.1 - 0.0032 17.8 0.0 0.13 12.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM02697.1 - 0.041 12.7 0.0 0.22 10.3 0.0 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 CCM02697.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NIR_SIR PF01077.17 CCM02699.1 - 9.8e-29 99.7 0.0 4.7e-28 97.5 0.0 2.0 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.10 CCM02699.1 - 1.9e-17 63.0 1.4 7.4e-13 48.3 1.8 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.22 CCM02699.1 - 8.5e-13 48.5 0.0 2.6e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.12 CCM02699.1 - 1.6e-11 43.6 0.0 3.5e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_2 PF07992.9 CCM02699.1 - 9.3e-09 35.4 0.6 1.9e-06 27.8 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Oxidored_molyb PF00174.14 CCM02700.1 - 2e-48 164.0 0.0 2.8e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain MFS_1 PF07690.11 CCM02700.1 - 3.5e-24 85.1 22.3 4.7e-24 84.7 15.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM02700.1 - 0.15 10.6 6.9 0.28 9.7 4.8 1.4 1 0 0 1 1 1 0 Sugar (and other) transporter NAD_binding_1 PF00175.16 CCM02701.1 - 3.5e-26 91.9 0.0 5.8e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCM02701.1 - 6.4e-23 80.7 0.0 1.2e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 CCM02701.1 - 3.4e-16 58.7 0.0 6.4e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mo-co_dimer PF03404.11 CCM02701.1 - 6.7e-13 48.4 0.4 1.2e-12 47.5 0.3 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_6 PF08030.7 CCM02701.1 - 4.5e-05 23.3 0.0 0.0015 18.4 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain CAS_CSE1 PF03378.10 CCM02704.1 - 4.2e-114 381.2 1.2 7.6e-114 380.3 0.9 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 CCM02704.1 - 5.8e-98 327.8 0.0 9e-98 327.2 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 CCM02704.1 - 3.2e-19 68.6 0.2 2.7e-18 65.6 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CCM02704.1 - 1.7e-05 25.0 9.8 0.15 12.3 0.3 4.8 4 1 0 5 5 5 3 HEAT repeats Xpo1 PF08389.7 CCM02704.1 - 0.027 14.3 0.3 0.91 9.4 0.0 3.3 3 0 0 3 3 3 0 Exportin 1-like protein DUF4419 PF14388.1 CCM02705.1 - 5.1e-83 278.7 0.0 6.1e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Grp1_Fun34_YaaH PF01184.14 CCM02706.1 - 8.6e-69 231.0 14.6 1.1e-68 230.6 10.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Acetyltransf_3 PF13302.1 CCM02707.1 - 7.8e-22 77.9 0.0 1.6e-21 76.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCM02707.1 - 3.4e-06 27.0 1.6 6.1e-05 22.9 1.1 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM02707.1 - 8.6e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCM02707.1 - 0.00033 20.3 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 CCM02707.1 - 0.024 14.6 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldedh PF00171.17 CCM02708.1 - 3.4e-183 609.2 0.1 3.8e-183 609.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pyr_redox_3 PF13738.1 CCM02709.1 - 4.2e-17 62.8 1.2 4.5e-09 36.6 0.2 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCM02709.1 - 1.2e-16 60.0 2.1 8.9e-15 53.8 0.0 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CCM02709.1 - 8.8e-12 44.5 1.0 1.6e-09 37.1 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM02709.1 - 2.6e-11 43.7 1.2 0.00063 19.6 0.0 3.5 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM02709.1 - 1.7e-08 34.7 1.1 0.011 16.1 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM02709.1 - 1.5e-07 31.3 0.4 1e-05 25.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCM02709.1 - 6.2e-06 25.4 2.4 0.00077 18.6 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 CCM02709.1 - 0.0004 19.4 9.7 0.0072 15.2 0.5 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM02709.1 - 0.00059 19.6 4.6 0.96 9.2 0.1 3.5 3 1 1 4 4 3 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 CCM02709.1 - 0.00091 18.4 0.0 0.31 10.1 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 CCM02709.1 - 0.0011 18.1 0.1 0.3 10.1 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 CCM02709.1 - 0.0054 15.6 0.4 0.0054 15.6 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 CCM02709.1 - 0.0075 15.9 1.0 0.18 11.4 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 CCM02709.1 - 0.0077 15.3 1.0 0.9 8.5 0.1 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 CCM02709.1 - 0.02 13.8 0.5 0.24 10.2 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.2 CCM02709.1 - 0.027 13.5 2.5 0.15 11.0 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 CCM02709.1 - 0.035 12.9 3.4 0.4 9.4 0.1 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.9 CCM02709.1 - 0.036 12.5 2.6 0.061 11.7 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.15 CCM02709.1 - 0.038 14.0 0.9 11 6.1 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CCM02709.1 - 0.12 12.6 0.6 25 5.2 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding p450 PF00067.17 CCM02710.1 - 2.2e-15 56.1 0.1 2.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 CCM02712.1 - 2.7e-27 95.7 2.6 3.4e-27 95.3 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM02712.1 - 3.9e-13 49.4 0.9 5.7e-13 48.9 0.7 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCM02712.1 - 0.00021 21.0 0.7 0.00048 19.8 0.5 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CCM02712.1 - 0.012 15.0 0.4 0.025 14.0 0.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 CCM02712.1 - 0.016 14.2 0.1 0.039 13.0 0.0 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 CCM02712.1 - 0.052 12.4 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phosducin PF02114.11 CCM02714.1 - 3.1e-14 52.3 0.0 1e-07 30.9 0.0 3.1 3 0 0 3 3 3 3 Phosducin p450 PF00067.17 CCM02715.1 - 3.5e-53 180.7 0.0 7.1e-53 179.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PfkB PF00294.19 CCM02716.1 - 3.7e-11 42.7 0.0 0.00041 19.5 0.0 3.1 2 1 0 3 3 3 3 pfkB family carbohydrate kinase Acetyltransf_1 PF00583.19 CCM02717.1 - 4.9e-10 39.3 0.0 8.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCM02717.1 - 1.5e-08 34.6 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCM02717.1 - 0.0004 20.2 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCM02717.1 - 0.026 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Kdo_hydroxy PF11004.3 CCM02718.1 - 0.14 11.1 0.2 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase WD40 PF00400.27 CCM02720.1 - 2.4e-46 154.0 14.0 1.2e-11 44.0 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CCM02720.1 - 0.00048 19.8 5.8 0.38 10.4 0.3 3.2 2 2 1 3 3 3 3 Transcription factor IIIC subunit delta N-term Sugar_tr PF00083.19 CCM02723.1 - 5.5e-120 400.9 23.8 8.1e-120 400.4 16.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM02723.1 - 1.5e-16 60.0 46.0 8.2e-13 47.7 12.3 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Inositol_P PF00459.20 CCM02724.1 - 6.9e-46 156.7 1.0 9.4e-40 136.6 0.1 2.0 2 0 0 2 2 2 2 Inositol monophosphatase family FHA PF00498.21 CCM02727.1 - 1.4e-08 34.7 0.0 3.3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain PIN_4 PF13638.1 CCM02728.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 PIN domain Prefoldin PF02996.12 CCM02729.1 - 1e-28 99.4 1.7 1.2e-28 99.1 1.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CCM02729.1 - 2.1e-05 24.2 2.2 0.0021 17.8 0.3 2.1 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 CCM02729.1 - 8.8e-05 22.2 0.2 0.00016 21.3 0.1 1.5 1 1 0 1 1 1 1 Prefoldin subunit TACC PF05010.9 CCM02729.1 - 0.0027 17.5 1.8 0.005 16.6 1.3 1.4 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) FlaC_arch PF05377.6 CCM02729.1 - 0.011 15.6 0.7 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) COG2 PF06148.6 CCM02729.1 - 0.011 15.5 1.2 0.93 9.3 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cep57_MT_bd PF06657.8 CCM02729.1 - 0.015 15.2 1.3 0.056 13.3 0.1 2.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Bacillus_HBL PF05791.6 CCM02729.1 - 0.019 14.3 4.3 0.39 10.0 0.3 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Seryl_tRNA_N PF02403.17 CCM02729.1 - 0.021 14.8 1.9 2.4 8.2 0.2 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 CCM02729.1 - 0.033 14.0 1.2 2.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 CCM02729.1 - 0.036 13.4 5.7 0.59 9.5 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.7 CCM02729.1 - 0.045 13.5 3.0 2.7 7.8 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 CCM02729.1 - 0.051 12.5 1.0 0.066 12.1 0.7 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) XkdW PF09636.5 CCM02729.1 - 0.074 12.9 0.5 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 XkdW protein Reo_sigmaC PF04582.7 CCM02729.1 - 0.088 11.9 0.6 4.4 6.4 0.1 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Snapin_Pallidin PF14712.1 CCM02729.1 - 0.09 13.1 4.9 1.6 9.0 0.2 2.4 1 1 1 2 2 2 0 Snapin/Pallidin Fib_alpha PF08702.5 CCM02729.1 - 0.1 12.7 6.2 0.3 11.2 1.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 CCM02729.1 - 0.11 12.3 1.6 5.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 CCM02729.1 - 0.13 12.4 3.5 7.1 6.8 0.1 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HrpB7 PF09486.5 CCM02729.1 - 0.17 11.8 3.3 4.9 7.0 0.2 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Mnd1 PF03962.10 CCM02729.1 - 0.22 11.1 4.5 1.9 8.1 3.2 1.9 1 1 0 1 1 1 0 Mnd1 family IncA PF04156.9 CCM02729.1 - 0.24 10.9 4.3 1.7 8.2 3.0 1.9 1 1 0 1 1 1 0 IncA protein DUF3296 PF11726.3 CCM02729.1 - 0.26 10.8 2.8 0.21 11.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3296) DUF4200 PF13863.1 CCM02729.1 - 0.29 11.0 7.4 3.5 7.5 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Cortex-I_coil PF09304.5 CCM02729.1 - 0.36 10.8 6.8 3.5 7.7 0.8 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF4298 PF14131.1 CCM02729.1 - 0.42 10.5 2.7 14 5.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) HR1 PF02185.11 CCM02729.1 - 0.45 10.2 3.6 5.6 6.7 0.1 2.7 2 1 0 2 2 2 0 Hr1 repeat IL6 PF00489.12 CCM02729.1 - 0.65 9.5 4.3 2 7.9 0.7 2.1 1 1 1 2 2 2 0 Interleukin-6/G-CSF/MGF family FliJ PF02050.11 CCM02729.1 - 0.92 9.5 8.4 1.6 8.8 2.3 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2347 PF09804.4 CCM02730.1 - 5.6e-44 150.5 0.0 1.2e-43 149.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 CCM02730.1 - 0.00028 21.0 0.0 0.0046 17.0 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 CCM02730.1 - 0.00038 19.0 0.1 4.1 5.7 0.1 3.2 3 0 0 3 3 3 3 Transport protein Avl9 SPA PF08616.5 CCM02730.1 - 0.004 16.8 0.0 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 Stabilization of polarity axis SAC3_GANP PF03399.11 CCM02731.1 - 2.7e-24 85.8 0.2 5.3e-24 84.9 0.2 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Fer4_17 PF13534.1 CCM02731.1 - 0.19 12.0 0.1 0.59 10.5 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pkinase PF00069.20 CCM02732.1 - 1.8e-74 250.1 0.0 2.4e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ATP_bind_1 PF03029.12 CCM02732.1 - 1.2e-71 241.0 0.0 2.1e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Pkinase_Tyr PF07714.12 CCM02732.1 - 1e-32 113.2 0.0 1.4e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FeoB_N PF02421.13 CCM02732.1 - 0.00031 20.0 0.8 0.11 11.7 0.0 2.9 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCM02732.1 - 0.00046 19.6 0.0 0.0083 15.5 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 CCM02732.1 - 0.0031 16.9 1.4 0.0046 16.3 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 CCM02732.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 CCM02732.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain APH PF01636.18 CCM02732.1 - 0.015 15.0 1.2 0.18 11.4 0.0 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family cobW PF02492.14 CCM02732.1 - 0.021 14.2 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 CCM02732.1 - 0.051 12.2 0.5 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Seadorna_VP7 PF07387.6 CCM02732.1 - 0.053 12.3 0.0 0.098 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AAA_17 PF13207.1 CCM02732.1 - 0.061 14.1 0.0 0.37 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Kinase-like PF14531.1 CCM02732.1 - 0.069 12.0 0.0 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like NB-ARC PF00931.17 CCM02732.1 - 0.13 11.0 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 CCM02732.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin WSC PF01822.14 CCM02733.1 - 9.2e-73 240.2 61.0 4.7e-20 71.2 7.2 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 CCM02733.1 - 3.7e-28 98.2 0.0 3.5e-26 91.7 0.0 3.0 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CCM02733.1 - 2.6e-22 78.7 0.1 5e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Phage_gp49_66 PF13876.1 CCM02733.1 - 5.6 7.1 5.6 20 5.3 0.6 2.5 2 0 0 2 2 2 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family RHH_1 PF01402.16 CCM02735.1 - 0.14 12.0 0.2 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Gti1_Pac2 PF09729.4 CCM02736.1 - 4.4e-55 186.0 0.0 6.3e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family Aldo_ket_red PF00248.16 CCM02737.1 - 1.8e-72 243.5 0.0 2e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MMR_HSR1 PF01926.18 CCM02738.1 - 1.2e-19 70.3 0.1 1e-14 54.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCM02738.1 - 2.4e-07 30.1 0.1 1.5e-05 24.3 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCM02738.1 - 8.6e-05 22.4 0.0 0.025 14.3 0.0 2.3 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 CCM02738.1 - 0.00015 21.3 0.0 0.0082 15.6 0.0 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCM02738.1 - 0.00015 20.9 0.0 0.0015 17.7 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCM02738.1 - 0.00061 19.8 0.4 0.27 11.1 0.0 2.7 2 2 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 CCM02738.1 - 0.0011 19.4 0.0 0.45 11.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 CCM02738.1 - 0.0012 17.7 0.1 0.0028 16.4 0.0 1.6 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 CCM02738.1 - 0.041 14.6 0.0 2.6 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CCM02738.1 - 0.059 12.8 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CCM02738.1 - 0.08 12.3 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CCM02738.1 - 0.14 11.8 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCM02738.1 - 0.22 11.8 1.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Pyr_redox_3 PF13738.1 CCM02739.1 - 6e-21 75.4 0.0 4.1e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCM02739.1 - 2.6e-15 55.6 0.1 3.2e-14 52.0 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 CCM02739.1 - 8.4e-12 44.9 0.2 2.9e-11 43.2 0.1 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CCM02739.1 - 1.4e-11 43.9 0.5 2.2e-09 36.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM02739.1 - 3.3e-06 27.1 0.0 0.00027 20.8 0.0 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM02739.1 - 7.5e-05 21.7 2.0 0.0047 15.8 0.1 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM02739.1 - 0.00072 19.3 0.5 0.2 11.4 0.1 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 CCM02739.1 - 0.016 15.3 0.0 0.97 9.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CCM02739.1 - 0.1 12.9 1.8 0.4 11.1 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCM02739.1 - 0.23 10.2 2.0 5.3 5.7 0.4 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 CCM02739.1 - 0.36 9.8 1.1 1.1 8.3 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 CCM02739.1 - 0.56 9.0 2.3 8.1 5.2 1.0 2.8 2 1 0 2 2 2 0 Lycopene cyclase protein Glyco_transf_49 PF13896.1 CCM02740.1 - 0.073 12.1 0.2 0.17 10.9 0.1 1.6 1 1 1 2 2 2 0 Glycosyl-transferase for dystroglycan MmgE_PrpD PF03972.9 CCM02741.1 - 1.6e-156 521.0 0.0 1.9e-156 520.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family GTP_EFTU PF00009.22 CCM02742.1 - 2.9e-47 160.5 0.0 1.6e-46 158.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCM02742.1 - 2.7e-31 107.6 0.0 8.6e-31 105.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 CCM02742.1 - 5.5e-30 103.0 0.0 1.1e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCM02742.1 - 3.1e-22 78.2 0.1 7.4e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCM02742.1 - 1.6e-12 47.3 0.0 4.5e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Pectinesterase PF01095.14 CCM02743.1 - 1e-23 83.3 0.0 3.3e-23 81.6 0.0 1.7 1 1 0 1 1 1 1 Pectinesterase CBM_21 PF03370.8 CCM02744.1 - 2.2e-22 79.1 0.0 6.7e-21 74.3 0.0 2.2 1 1 0 1 1 1 1 Putative phosphatase regulatory subunit TPMT PF05724.6 CCM02748.1 - 5.9e-37 127.2 0.0 7.8e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 CCM02748.1 - 1.5e-11 44.1 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM02748.1 - 5.4e-11 43.0 0.0 8.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM02748.1 - 6.4e-08 32.4 0.0 8.2e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM02748.1 - 6.5e-08 32.9 0.0 9.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM02748.1 - 7.2e-08 32.8 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM02748.1 - 1.3e-07 31.6 0.0 2.9e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM02748.1 - 2.1e-07 31.2 0.0 2.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CCM02748.1 - 2e-05 23.8 0.0 2.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 CCM02748.1 - 0.0046 16.0 0.0 0.0094 15.0 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 CCM02748.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MRI PF15325.1 CCM02749.1 - 6 7.8 6.4 1.5 9.8 2.2 1.5 2 0 0 2 2 2 0 Modulator of retrovirus infection TPR_9 PF13371.1 CCM02751.1 - 0.036 13.9 0.2 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat NST1 PF13945.1 CCM02751.1 - 0.28 11.2 11.0 0.039 14.0 3.6 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator BLVR PF06375.6 CCM02751.1 - 0.75 9.6 9.4 2.1 8.1 4.0 2.3 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DAP PF15228.1 CCM02752.1 - 0.015 16.0 1.6 0.015 16.0 1.1 2.4 1 1 1 2 2 2 0 Death-associated protein Ribosomal_L28e PF01778.12 CCM02753.1 - 8.9e-14 51.9 0.0 5.8e-07 29.9 0.0 2.2 1 1 1 2 2 2 2 Ribosomal L28e protein family O-FucT PF10250.4 CCM02754.1 - 7.8e-06 25.2 0.0 1.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HAD_2 PF13419.1 CCM02754.1 - 0.057 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 CCM02755.1 - 0.00072 19.1 1.1 0.0058 16.2 0.8 2.2 1 1 0 1 1 1 1 Homeobox domain O-FucT PF10250.4 CCM02755.1 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Homeobox_KN PF05920.6 CCM02755.1 - 0.093 12.4 0.2 0.3 10.8 0.2 1.9 1 1 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 CCM02756.1 - 0.00021 20.8 1.0 0.0017 17.9 0.3 2.5 1 1 1 2 2 2 2 Homeobox domain Homeobox_KN PF05920.6 CCM02756.1 - 0.022 14.4 1.0 0.23 11.1 0.2 2.6 2 0 0 2 2 2 0 Homeobox KN domain DUF4095 PF13338.1 CCM02756.1 - 0.1 12.7 0.1 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4095) Ribosomal_S15 PF00312.17 CCM02757.1 - 8e-19 67.1 1.0 1.4e-18 66.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 NUFIP1 PF10453.4 CCM02757.1 - 1.3 8.5 4.9 12 5.5 0.0 2.6 1 1 1 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) RhoGEF PF00621.15 CCM02758.1 - 1.6e-37 129.1 0.0 2.4e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 CCM02758.1 - 8.1e-06 25.9 0.0 3e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 PH domain NAGLU PF05089.7 CCM02759.1 - 2.3e-124 414.4 8.9 3.4e-124 413.9 6.2 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 CCM02759.1 - 2.3e-62 210.8 1.6 3.2e-62 210.3 1.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 CCM02759.1 - 4.2e-07 29.5 0.0 8.2e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain NGP1NT PF08153.7 CCM02760.1 - 3.4e-46 156.3 1.1 4.4e-46 156.0 0.0 1.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CCM02760.1 - 1.8e-19 69.8 0.1 8.5e-16 57.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCM02760.1 - 3.4e-06 26.4 0.1 5.8e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 CCM02760.1 - 0.00021 20.5 0.1 0.14 11.3 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM02760.1 - 0.00027 20.4 0.5 0.028 13.8 0.1 2.8 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCM02760.1 - 0.0004 19.6 0.1 0.00076 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCM02760.1 - 0.14 12.0 5.1 3.9 7.2 0.1 3.6 3 1 1 4 4 4 0 Dynamin family Enolase_C PF00113.17 CCM02761.1 - 2.7e-147 489.4 0.0 3.7e-147 489.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CCM02761.1 - 2.4e-56 189.3 0.2 3.8e-56 188.6 0.2 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CCM02761.1 - 5.2e-06 26.4 0.0 1.4e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 CCM02761.1 - 0.00063 18.7 0.6 0.0013 17.7 0.1 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 CCM02761.1 - 0.024 15.1 0.0 0.053 14.0 0.0 1.6 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF2051 PF09738.4 CCM02762.1 - 0.13 11.5 5.8 0.18 11.0 4.0 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Glyco_hydro_47 PF01532.15 CCM02763.1 - 1.7e-141 471.9 0.0 2e-141 471.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APH PF01636.18 CCM02764.1 - 2.7e-07 30.5 0.0 1e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 CCM02764.1 - 7.6e-06 24.8 0.0 0.023 13.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) zf-C2H2_4 PF13894.1 CCM02765.1 - 2.3e-07 30.6 9.4 0.0033 17.6 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM02765.1 - 2.8e-07 30.4 17.4 5.9e-05 23.1 1.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CCM02765.1 - 0.026 14.4 3.0 0.15 12.0 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CCM02765.1 - 0.07 13.3 0.8 17 5.7 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 CCM02765.1 - 1.9 8.1 7.0 8.5 6.1 0.1 3.0 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2 PF00096.21 CCM02767.1 - 6.3e-09 35.6 14.3 0.00024 21.2 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCM02767.1 - 2.4e-07 30.7 4.1 2.4e-07 30.7 2.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCM02767.1 - 9.7e-07 28.6 12.3 0.0012 19.0 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCM02767.1 - 1.9e-06 27.5 0.3 4.4e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.7 CCM02767.1 - 0.0085 16.1 7.9 0.017 15.2 5.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.9 CCM02767.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.3 CCM02767.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.2 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CCM02767.1 - 0.91 9.3 7.0 6 6.7 0.2 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 CCM02767.1 - 1.1 9.3 5.4 2.7 8.1 3.8 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CCM02767.1 - 1.5 9.1 4.6 0.62 10.3 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type EF-hand_1 PF00036.27 CCM02768.1 - 6.8e-24 81.3 18.4 2.9e-09 35.5 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCM02768.1 - 1e-22 80.0 14.8 7.9e-12 45.1 3.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCM02768.1 - 1e-20 71.6 15.0 1.7e-08 33.6 0.1 4.5 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CCM02768.1 - 1.7e-15 56.3 16.2 3e-09 36.3 1.6 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CCM02768.1 - 4.9e-15 54.0 7.6 8.8e-05 21.6 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 CCM02768.1 - 1.8e-10 40.6 1.3 0.00017 21.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CCM02768.1 - 7.4e-08 32.0 8.7 0.0007 19.3 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 CCM02768.1 - 0.0036 16.8 0.1 0.076 12.5 0.0 2.3 2 1 0 2 2 2 1 Caleosin related protein DUF3164 PF11363.3 CCM02768.1 - 0.036 13.4 0.6 0.87 8.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3164) SPARC_Ca_bdg PF10591.4 CCM02768.1 - 0.065 13.2 3.1 1.4 8.9 0.1 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MerR-DNA-bind PF09278.6 CCM02768.1 - 0.26 11.7 2.8 18 5.8 0.2 3.3 3 0 0 3 3 3 0 MerR, DNA binding EF-hand_like PF09279.6 CCM02768.1 - 2.2 8.3 5.4 2 8.5 0.5 2.6 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like MgtE_N PF03448.12 CCM02768.1 - 2.8 8.2 7.0 0.45 10.8 1.1 2.3 3 0 0 3 3 2 0 MgtE intracellular N domain TauD PF02668.11 CCM02769.1 - 5e-40 137.7 0.2 2.5e-38 132.2 0.1 2.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.11 CCM02770.1 - 2.3e-43 148.7 0.1 3.2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NACHT PF05729.7 CCM02771.1 - 0.059 13.0 0.1 8.6 5.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain GalKase_gal_bdg PF10509.4 CCM02772.1 - 2e-19 68.5 0.1 3.8e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CCM02772.1 - 1.2e-13 50.8 2.3 3.4e-13 49.4 1.0 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCM02772.1 - 4.9e-13 49.0 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal MFS_1 PF07690.11 CCM02774.1 - 3.4e-29 101.6 22.4 3.9e-29 101.4 13.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 CCM02774.1 - 0.041 13.9 1.5 0.92 9.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DIOX_N PF14226.1 CCM02775.1 - 1.2e-16 61.2 0.0 3.3e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM02775.1 - 7.2e-11 42.2 0.0 1.3e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1793 PF08760.6 CCM02776.1 - 1.6e-20 73.6 0.3 2.8e-20 72.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) SKG6 PF08693.5 CCM02776.1 - 0.0014 17.8 0.6 0.0014 17.8 0.4 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Syndecan PF01034.15 CCM02776.1 - 0.011 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 CCM02776.1 - 0.086 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RTBV_P12 PF06361.6 CCM02776.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.1 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein TFIIF_beta PF02270.10 CCM02777.1 - 7.5e-48 163.7 0.0 2.2e-45 155.6 0.0 2.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 CCM02777.1 - 7.4e-05 22.2 0.0 8.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Nucleoplasmin PF03066.10 CCM02777.1 - 0.23 10.9 3.4 0.5 9.8 2.4 1.6 1 0 0 1 1 1 0 Nucleoplasmin PPI_Ypi1 PF07491.6 CCM02778.1 - 2.7e-23 81.3 1.6 6.4e-23 80.1 1.1 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.9 CCM02778.1 - 0.29 9.1 2.0 0.33 8.9 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 CCM02778.1 - 0.73 8.1 7.1 0.91 7.8 4.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-MYND PF01753.13 CCM02779.1 - 3.7e-11 42.6 10.5 7.9e-11 41.6 7.3 1.6 1 0 0 1 1 1 1 MYND finger IDO PF01231.13 CCM02780.1 - 8.8e-112 373.6 0.0 1.5e-111 372.8 0.0 1.3 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1793 PF08760.6 CCM02781.1 - 3.7e-29 101.7 2.5 7.7e-29 100.7 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) SKG6 PF08693.5 CCM02781.1 - 0.00038 19.7 1.6 0.00072 18.8 1.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 CCM02781.1 - 0.038 14.3 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3713 PF12506.3 CCM02781.1 - 0.7 9.9 4.3 6 6.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) DUF1212 PF06738.7 CCM02782.1 - 3e-23 82.2 0.1 4.1e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1212) Acetyltransf_1 PF00583.19 CCM02783.1 - 3e-11 43.1 0.1 4.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCM02783.1 - 3.8e-05 23.3 0.0 6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CCM02783.1 - 6.9e-05 22.9 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCM02783.1 - 0.00082 19.3 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCM02783.1 - 0.002 18.2 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCM02783.1 - 0.0071 16.1 0.1 0.014 15.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCM02783.1 - 0.03 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.21 CCM02785.1 - 3.7e-14 52.3 0.0 6.1e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM02785.1 - 7.7e-09 35.2 0.1 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ALO PF04030.9 CCM02786.1 - 2e-06 27.5 2.0 5.3e-06 26.2 1.4 1.7 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CCM02786.1 - 2.2e-06 27.1 0.0 0.051 13.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain IncA PF04156.9 CCM02788.1 - 0.042 13.4 2.7 0.05 13.1 1.9 1.3 1 0 0 1 1 1 0 IncA protein Septin PF00735.13 CCM02789.1 - 5.7e-108 360.2 0.0 8.3e-108 359.6 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCM02789.1 - 1.8e-06 27.8 0.0 3.5e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCM02789.1 - 0.0031 16.7 0.4 0.011 14.8 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCM02789.1 - 0.0036 17.1 3.5 0.37 10.6 0.0 2.7 2 1 0 3 3 3 2 Dynamin family AIG1 PF04548.11 CCM02789.1 - 0.004 16.2 0.0 0.007 15.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_17 PF13207.1 CCM02789.1 - 0.0046 17.7 0.9 0.033 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain IIGP PF05049.8 CCM02789.1 - 0.012 14.4 0.1 0.024 13.4 0.1 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.22 CCM02789.1 - 0.014 14.8 0.0 0.13 11.6 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 CCM02789.1 - 0.02 15.4 0.1 0.052 14.0 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 CCM02789.1 - 0.021 14.3 0.1 0.043 13.2 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 CCM02789.1 - 0.088 12.6 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CCM02789.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MutS_III PF05192.13 CCM02790.1 - 3.5e-31 108.5 0.1 7.5e-31 107.5 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCM02790.1 - 2.1e-22 79.2 0.0 4.1e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CCM02790.1 - 4e-10 39.8 0.0 1.2e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_V PF00488.16 CCM02791.1 - 2.3e-82 275.9 0.0 2.8e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 MutS domain V AAA_29 PF13555.1 CCM02791.1 - 0.00067 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CCM02791.1 - 0.0048 17.2 0.0 0.0071 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCM02791.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Aconitase PF00330.15 CCM02792.1 - 4.4e-149 496.9 0.2 9.6e-148 492.5 0.1 2.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCM02792.1 - 3.7e-35 120.8 0.0 6.1e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Oxysterol_BP PF01237.13 CCM02794.1 - 1e-111 372.8 0.0 1.6e-111 372.2 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 CCM02794.1 - 1e-09 38.3 0.2 3.8e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Ras PF00071.17 CCM02795.1 - 1.2e-52 177.5 0.1 1.5e-52 177.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM02795.1 - 5.7e-18 65.5 0.0 1.1e-17 64.5 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CCM02795.1 - 7.6e-12 44.8 0.0 1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM02795.1 - 1e-06 28.3 0.0 2.5e-05 23.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCM02795.1 - 2.4e-06 27.4 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCM02795.1 - 0.0002 20.5 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 CCM02795.1 - 0.00032 20.3 0.2 0.022 14.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CCM02795.1 - 0.00063 19.2 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CCM02795.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CCM02795.1 - 0.0018 17.4 0.0 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 CCM02795.1 - 0.0027 16.7 0.2 0.07 12.1 0.0 2.2 2 1 0 2 2 2 1 Septin cobW PF02492.14 CCM02795.1 - 0.0029 17.0 0.0 0.011 15.1 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CCM02795.1 - 0.0076 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 CCM02795.1 - 0.0077 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CCM02795.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CCM02795.1 - 0.018 14.7 0.1 0.14 11.8 0.0 2.0 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CCM02795.1 - 0.023 14.1 0.1 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 CCM02795.1 - 0.026 14.5 0.0 0.05 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 CCM02795.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATG16 PF08614.6 CCM02796.1 - 1.4e-35 122.8 12.4 1.4e-35 122.8 8.6 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF2408 PF10303.4 CCM02796.1 - 0.042 13.9 10.8 0.024 14.7 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) IncA PF04156.9 CCM02796.1 - 0.083 12.4 23.8 0.32 10.5 10.3 2.1 1 1 1 2 2 2 0 IncA protein EzrA PF06160.7 CCM02796.1 - 0.09 10.9 15.4 0.13 10.4 10.7 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA PPR_2 PF13041.1 CCM02796.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 PPR repeat family Snapin_Pallidin PF14712.1 CCM02796.1 - 0.13 12.5 14.6 0.066 13.5 3.6 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Perilipin PF03036.11 CCM02796.1 - 0.45 9.2 9.7 0.21 10.4 0.4 2.1 1 1 1 2 2 2 0 Perilipin family Med10 PF09748.4 CCM02796.1 - 0.63 9.8 6.6 8.4 6.2 4.0 2.4 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Spc7 PF08317.6 CCM02796.1 - 0.78 8.3 18.8 0.47 9.0 11.1 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.7 CCM02796.1 - 0.98 9.6 19.7 2.5 8.3 5.6 2.8 2 1 0 2 2 2 0 Centromere protein H (CENP-H) FlxA PF14282.1 CCM02796.1 - 1.2 9.1 23.2 0.47 10.4 0.1 3.2 1 1 1 2 2 2 0 FlxA-like protein Reo_sigmaC PF04582.7 CCM02796.1 - 2.8 7.0 6.9 1.7 7.7 3.4 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fzo_mitofusin PF04799.8 CCM02796.1 - 3.5 6.9 7.0 0.8 9.0 1.8 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF4094 PF13334.1 CCM02796.1 - 6.1 7.3 12.7 18 5.7 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) DUF1664 PF07889.7 CCM02796.1 - 8 6.2 10.2 3.5 7.4 2.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.4 CCM02796.1 - 8.5 6.3 12.0 3.8 7.4 6.5 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein RRM_1 PF00076.17 CCM02800.1 - 8.4e-54 179.1 0.0 7.5e-19 67.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM02800.1 - 2.9e-40 136.0 0.0 3.5e-13 49.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM02800.1 - 4.8e-26 90.3 0.0 1e-08 34.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCM02800.1 - 0.0003 20.5 0.0 0.33 10.7 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 CCM02800.1 - 0.0023 17.8 0.0 3.8 7.5 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Asn_synthase PF00733.16 CCM02801.1 - 1.4e-47 162.3 0.0 4.5e-47 160.6 0.0 1.8 1 1 0 1 1 1 1 Asparagine synthase Band_7 PF01145.20 CCM02801.1 - 2.4e-24 86.2 0.2 4.6e-24 85.3 0.2 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family GATase_7 PF13537.1 CCM02801.1 - 2.9e-08 33.4 0.0 1.9e-07 30.8 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCM02801.1 - 0.033 14.1 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 Glutamine amidotransferase domain QueC PF06508.8 CCM02801.1 - 0.16 11.2 0.0 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Big_3 PF07523.7 CCM02801.1 - 0.2 11.7 0.0 0.5 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) 6PGD PF00393.14 CCM02802.1 - 2.2e-132 440.6 0.0 2.6e-132 440.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CCM02802.1 - 1.8e-50 170.9 0.0 2.8e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCM02802.1 - 0.028 14.8 0.0 0.06 13.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CCM02802.1 - 0.033 13.6 0.1 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.1 CCM02802.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 CCM02802.1 - 0.058 13.0 0.3 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCM02802.1 - 0.07 12.2 0.1 0.23 10.6 0.1 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_4 PF01063.14 CCM02803.1 - 4.2e-18 65.6 0.0 5.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Trypsin_2 PF13365.1 CCM02804.1 - 6.1e-08 32.6 0.0 9.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain SKG6 PF08693.5 CCM02805.1 - 2.4e-06 26.7 4.7 4.3e-06 25.9 3.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 CCM02805.1 - 0.00017 21.0 0.9 0.00031 20.2 0.7 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4448 PF14610.1 CCM02805.1 - 0.0053 16.2 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Shisa PF13908.1 CCM02805.1 - 0.013 15.6 0.1 0.013 15.6 0.1 2.5 1 1 1 2 2 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 CCM02805.1 - 0.014 13.6 1.4 0.026 12.8 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF2207 PF09972.4 CCM02805.1 - 0.023 13.2 0.0 0.07 11.7 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.1 CCM02805.1 - 0.055 13.8 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 CCM02805.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CBM_6 PF03422.10 CCM02805.1 - 0.075 13.1 0.4 9.1 6.4 0.1 2.6 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) Plasmodium_Vir PF05795.6 CCM02805.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Gemini_mov PF01708.11 CCM02805.1 - 0.86 9.1 0.0 0.86 9.1 0.0 2.5 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF788 PF05620.6 CCM02806.1 - 7.8e-41 139.7 0.0 8.8e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) MrpF_PhaF PF04066.8 CCM02806.1 - 0.085 13.1 0.2 0.17 12.1 0.2 1.5 1 0 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Myb_DNA-binding PF00249.26 CCM02807.1 - 8.4e-48 160.2 2.0 4.4e-13 49.0 0.1 5.5 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCM02807.1 - 3.1e-40 136.0 0.7 2.3e-11 43.5 0.0 5.7 3 2 2 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CCM02807.1 - 2.1e-07 30.9 6.5 0.22 11.6 0.0 5.9 5 2 0 5 5 5 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 CCM02807.1 - 2.8e-05 23.9 1.8 0.05 13.4 0.1 3.5 1 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 CCM02807.1 - 0.12 12.2 0.8 18 5.3 0.0 3.8 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain TAF8_C PF10406.4 CCM02808.1 - 2.2e-06 27.5 1.0 2.2e-06 27.5 0.7 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 CCM02808.1 - 0.00011 21.9 0.0 0.0012 18.4 0.0 2.1 1 1 0 1 1 1 1 Bromodomain associated Aminotran_3 PF00202.16 CCM02809.1 - 1.2e-88 297.2 0.0 1.6e-88 296.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CCM02810.1 - 2.5e-73 247.1 0.0 3.5e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCM02810.1 - 9.4e-06 24.6 0.0 2.6e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CCM02810.1 - 9.6e-05 20.8 0.0 0.00016 20.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pertussis_S1 PF02917.9 CCM02810.1 - 0.0036 16.9 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Pertussis toxin, subunit 1 DUF2373 PF10180.4 CCM02811.1 - 2.6e-17 62.1 0.2 4.9e-17 61.2 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) CDC27 PF09507.5 CCM02811.1 - 6.1 5.9 50.9 0.72 9.0 8.8 2.2 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 Arf PF00025.16 CCM02812.1 - 3.6e-71 237.9 0.0 4.3e-71 237.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCM02812.1 - 1.4e-14 53.7 0.0 1.8e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCM02812.1 - 1.1e-12 47.3 0.3 5.7e-08 31.8 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCM02812.1 - 3.8e-10 39.3 0.0 4.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CCM02812.1 - 4.7e-10 39.0 0.0 5.2e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM02812.1 - 8.7e-08 32.6 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCM02812.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thioredoxin_2 PF13098.1 CCM02812.1 - 0.15 12.2 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain WD40 PF00400.27 CCM02813.1 - 1.7e-22 78.3 12.1 6.3e-09 35.3 0.6 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Iso_dh PF00180.15 CCM02814.1 - 9.7e-100 333.8 0.0 1.1e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AvrD PF05655.6 CCM02814.1 - 0.12 11.2 0.1 1 8.1 0.0 2.0 2 0 0 2 2 2 0 Pseudomonas avirulence D protein (AvrD) Abhydrolase_6 PF12697.2 CCM02816.1 - 2.1e-34 119.4 1.0 3.2e-34 118.7 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM02816.1 - 9.1e-20 71.1 0.0 1.8e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM02816.1 - 7.9e-15 54.8 0.1 1.6e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCM02816.1 - 1.2e-06 28.2 0.0 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 CCM02816.1 - 3.2e-06 26.7 0.0 7.7e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.16 CCM02816.1 - 0.00013 21.2 0.0 0.26 10.4 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family BAAT_C PF08840.6 CCM02816.1 - 0.00014 21.6 0.0 0.07 12.8 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 CCM02816.1 - 0.0006 19.3 0.0 0.08 12.3 0.0 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 CCM02816.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase UPF0227 PF05728.7 CCM02816.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DLH PF01738.13 CCM02816.1 - 0.004 16.4 0.3 0.12 11.6 0.0 2.5 2 1 1 3 3 3 1 Dienelactone hydrolase family DUF915 PF06028.6 CCM02816.1 - 0.021 13.9 0.0 0.45 9.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 CCM02816.1 - 0.027 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF2048 PF09752.4 CCM02816.1 - 0.027 13.3 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Peptidase_S15 PF02129.13 CCM02816.1 - 0.03 13.7 0.1 0.4 10.0 0.1 2.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.9 CCM02816.1 - 0.046 12.1 0.0 0.076 11.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family Folate_carrier PF01770.13 CCM02816.1 - 0.074 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Lipase_3 PF01764.20 CCM02816.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ribosomal_S11 PF00411.14 CCM02817.1 - 4.6e-08 33.2 0.0 6.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 UCR_UQCRX_QCR9 PF05365.7 CCM02818.1 - 2.3e-26 91.1 3.1 2.6e-26 91.0 2.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like IPK PF03770.11 CCM02819.1 - 7.9e-51 172.5 0.0 1.2e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase RRM_1 PF00076.17 CCM02820.1 - 1.2e-16 60.0 0.0 1.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM02820.1 - 5.6e-14 51.8 0.0 8.7e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM02820.1 - 7e-07 29.0 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_16 PF13432.1 CCM02821.1 - 6.8e-06 26.6 0.0 0.13 12.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM02821.1 - 1.3e-05 25.3 1.1 0.06 14.0 0.1 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCM02821.1 - 0.00013 21.5 0.1 0.19 11.3 0.0 2.6 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CCM02821.1 - 0.0073 16.1 0.0 9 6.4 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCM02821.1 - 0.012 15.2 0.0 5.7 6.7 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCM02821.1 - 0.038 14.3 1.7 3.4 8.0 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.2 CCM02822.1 - 2.6e-05 23.8 0.3 6e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM02822.1 - 0.14 11.8 0.2 0.47 10.1 0.1 1.9 1 1 0 1 1 1 0 F-box domain Ribosomal_L19 PF01245.15 CCM02824.1 - 5.4e-18 64.8 0.0 8.1e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Fungal_trans PF04082.13 CCM02825.1 - 5.5e-37 127.0 0.0 8.2e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM02825.1 - 6e-09 35.6 12.8 1.3e-08 34.5 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 CCM02826.1 - 4.1e-32 111.3 0.8 6.2e-32 110.7 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 CCM02826.1 - 1.8e-13 50.9 0.5 2.9e-13 50.2 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCM02826.1 - 3.5e-13 48.8 0.0 9e-13 47.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CCM02826.1 - 2.5e-11 44.1 0.0 6.3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Hemerythrin PF01814.18 CCM02827.1 - 0.022 14.9 1.2 0.038 14.1 0.9 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain ECH PF00378.15 CCM02828.1 - 4.1e-20 71.9 0.0 5.2e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family B12-binding_2 PF02607.12 CCM02828.1 - 0.13 12.3 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain DUF2423 PF10338.4 CCM02829.1 - 2.1e-15 56.4 4.7 3.2e-15 55.8 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) BOP1NT PF08145.7 CCM02832.1 - 6.7e-100 334.1 10.7 9.6e-100 333.5 7.4 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CCM02832.1 - 5.5e-23 79.9 3.9 7.8e-07 28.7 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF1939 PF09154.5 CCM02832.1 - 0.11 12.3 0.1 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) Nop14 PF04147.7 CCM02832.1 - 2.5 5.9 24.9 3.8 5.3 17.2 1.2 1 0 0 1 1 1 0 Nop14-like family Actin PF00022.14 CCM02833.1 - 8e-113 376.8 0.0 9.1e-113 376.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCM02833.1 - 2e-07 29.9 0.0 0.015 13.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Sedlin_N PF04628.8 CCM02835.1 - 1.4e-40 138.2 0.0 1.9e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CCM02835.1 - 8.6e-09 35.2 0.0 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Sybindin-like family Spt5-NGN PF03439.8 CCM02835.1 - 0.042 13.5 0.0 0.35 10.6 0.0 2.1 1 1 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Rhomboid PF01694.17 CCM02836.1 - 9.3e-23 80.8 11.1 1.3e-22 80.4 6.6 1.9 2 0 0 2 2 2 1 Rhomboid family AAA PF00004.24 CCM02838.1 - 7.1e-33 113.6 0.0 1.4e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCM02838.1 - 4.5e-08 33.3 0.1 2.9e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM02838.1 - 1.3e-07 31.7 0.2 4.2e-07 30.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCM02838.1 - 1.7e-07 32.0 0.0 5.6e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCM02838.1 - 2.9e-06 27.2 0.0 8.4e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCM02838.1 - 5.8e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCM02838.1 - 1.3e-05 24.3 0.0 0.0077 15.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_2 PF07724.9 CCM02838.1 - 1.6e-05 24.9 0.0 4.2e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CCM02838.1 - 1.9e-05 24.2 0.0 0.00052 19.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 CCM02838.1 - 2e-05 24.4 0.1 0.026 14.2 0.1 2.2 1 1 1 2 2 2 2 Archaeal ATPase AAA_18 PF13238.1 CCM02838.1 - 3e-05 24.3 0.0 5.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCM02838.1 - 3.1e-05 23.6 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCM02838.1 - 7.8e-05 22.1 1.0 0.11 11.8 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 CCM02838.1 - 0.0001 22.0 0.1 0.00035 20.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 CCM02838.1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 CCM02838.1 - 0.00054 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 CCM02838.1 - 0.00056 18.7 0.0 0.00086 18.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 CCM02838.1 - 0.001 18.7 0.1 0.0051 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CCM02838.1 - 0.0014 18.3 0.1 0.0036 16.9 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 CCM02838.1 - 0.0023 17.9 0.0 0.0044 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCM02838.1 - 0.0024 16.9 0.0 0.0099 14.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CCM02838.1 - 0.0037 17.4 0.0 0.0096 16.0 0.0 1.7 2 0 0 2 2 1 1 RNA helicase IstB_IS21 PF01695.12 CCM02838.1 - 0.0043 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PduV-EutP PF10662.4 CCM02838.1 - 0.0059 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 CCM02838.1 - 0.0067 15.5 0.0 0.014 14.4 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_30 PF13604.1 CCM02838.1 - 0.0071 15.9 0.0 0.041 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CCM02838.1 - 0.0083 15.3 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 CCM02838.1 - 0.015 14.4 0.0 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CCM02838.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.6 CCM02838.1 - 0.027 14.0 0.1 0.091 12.3 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CCM02838.1 - 0.03 14.6 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CCM02838.1 - 0.036 13.0 0.0 0.062 12.2 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 CCM02838.1 - 0.037 13.5 0.1 0.91 8.9 0.0 2.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 CCM02838.1 - 0.041 13.5 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 CCM02838.1 - 0.048 12.6 0.0 1.3 7.9 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain CPT PF07931.7 CCM02838.1 - 0.05 13.2 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin2 PF13189.1 CCM02838.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family Rdx PF10262.4 CCM02839.1 - 3.8e-20 71.6 0.0 1.8e-19 69.5 0.0 1.8 1 1 1 2 2 2 1 Rdx family SNARE_assoc PF09335.6 CCM02840.1 - 1.3e-15 57.6 8.3 1.3e-15 57.6 5.7 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2910 PF11139.3 CCM02840.1 - 0.0078 15.3 4.5 0.016 14.3 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2910) Chromate_transp PF02417.10 CCM02840.1 - 0.047 13.2 8.2 0.017 14.7 3.5 1.9 1 1 0 1 1 1 0 Chromate transporter PDGLE PF13190.1 CCM02840.1 - 0.067 12.8 9.0 0.45 10.2 0.1 3.1 3 0 0 3 3 3 0 PDGLE domain DUF4231 PF14015.1 CCM02840.1 - 5.4 7.0 6.5 0.47 10.4 0.6 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PEX11 PF05648.9 CCM02842.1 - 1.4e-12 47.3 0.7 5.2e-06 25.8 0.0 2.4 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Tctex-1 PF03645.8 CCM02843.1 - 8.1e-06 25.6 0.0 9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF2312 PF10073.4 CCM02843.1 - 0.2 11.0 0.9 0.26 10.6 0.2 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) PPR_2 PF13041.1 CCM02845.1 - 0.00013 21.8 0.0 0.0089 15.9 0.0 3.1 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.1 CCM02845.1 - 0.28 11.5 1.6 5.9 7.4 0.0 3.6 4 0 0 4 4 4 0 Pentatricopeptide repeat domain CLASP_N PF12348.3 CCM02847.1 - 9e-76 254.2 0.0 7.5e-71 238.1 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 CCM02847.1 - 8.1e-07 28.6 0.3 0.59 10.3 0.0 4.8 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 CCM02847.1 - 0.00015 22.1 3.1 1 9.9 0.3 5.2 5 0 0 5 5 5 2 HEAT-like repeat Cohesin_HEAT PF12765.2 CCM02847.1 - 0.03 14.2 0.2 25 4.9 0.0 3.5 2 1 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF3644 PF12358.3 CCM02847.1 - 0.19 11.9 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) SHQ1 PF04925.10 CCM02849.1 - 2.2e-47 160.9 0.0 3.3e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.11 CCM02849.1 - 0.007 16.8 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 CS domain PIH1 PF08190.7 CCM02849.1 - 0.0083 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Chorismate_bind PF00425.13 CCM02850.1 - 2e-89 299.3 0.0 3.1e-89 298.7 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CCM02850.1 - 1.5e-29 102.8 0.0 1.3e-28 99.7 0.0 2.2 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.15 CCM02851.1 - 2.5e-46 157.5 0.0 4.9e-44 150.0 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S2 HSP70 PF00012.15 CCM02852.1 - 5.9e-243 807.2 3.9 7.3e-243 806.9 2.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCM02852.1 - 6.3e-16 57.8 0.1 4.3e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 CCM02852.1 - 0.004 16.0 0.6 0.041 12.7 0.2 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 CCM02852.1 - 0.0086 15.3 0.0 0.65 9.2 0.0 2.4 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.11 CCM02852.1 - 0.032 13.8 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 CCM02852.1 - 0.037 12.9 0.0 0.087 11.7 0.0 1.6 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.13 CCM02852.1 - 0.067 12.2 0.7 0.22 10.6 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase AAA PF00004.24 CCM02853.1 - 3.4e-13 49.9 0.0 9.8e-13 48.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCM02853.1 - 2.5e-12 46.7 0.0 1.6e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CCM02853.1 - 1.4e-09 37.2 0.0 2e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 CCM02853.1 - 1.7e-09 37.5 0.0 4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CCM02853.1 - 7.3e-07 29.3 0.0 3.3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCM02853.1 - 5.8e-05 23.1 0.0 0.00048 20.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CCM02853.1 - 0.00022 20.3 0.0 0.00046 19.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 CCM02853.1 - 0.00025 20.5 0.2 0.033 13.6 0.0 2.8 2 2 1 3 3 3 1 AAA-like domain AAA_19 PF13245.1 CCM02853.1 - 0.00029 20.5 0.0 0.00074 19.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CCM02853.1 - 0.00032 20.5 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCM02853.1 - 0.00079 19.0 0.0 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCM02853.1 - 0.00092 18.9 0.0 0.0042 16.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CCM02853.1 - 0.00096 18.7 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCM02853.1 - 0.0039 16.3 0.0 0.093 11.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CCM02853.1 - 0.0041 17.9 0.0 0.024 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 CCM02853.1 - 0.017 14.5 0.1 0.63 9.5 0.0 2.6 2 1 0 3 3 3 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 CCM02853.1 - 0.018 14.5 0.1 0.32 10.4 0.0 2.1 1 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 CCM02853.1 - 0.018 15.3 0.0 0.024 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CCM02853.1 - 0.024 14.2 0.0 0.064 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CCM02853.1 - 0.026 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 CCM02853.1 - 0.026 14.3 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCM02853.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CCM02853.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCM02853.1 - 0.086 12.2 0.0 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF3323 PF11796.3 CCM02853.1 - 0.1 11.8 0.1 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DUF815 PF05673.8 CCM02853.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CAF1A PF12253.3 CCM02854.1 - 3.3e-21 75.1 3.3 3.3e-21 75.1 2.3 2.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A Spc24 PF08286.6 CCM02855.1 - 0.00014 21.5 1.3 0.00014 21.5 0.9 1.6 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 CCM02855.1 - 0.00021 20.6 2.2 0.00024 20.4 1.5 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AAA_27 PF13514.1 CCM02855.1 - 0.0093 13.7 7.5 0.0097 13.6 5.2 1.0 1 0 0 1 1 1 1 AAA domain ATG16 PF08614.6 CCM02855.1 - 0.013 15.3 4.4 0.016 15.0 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 CCM02855.1 - 0.036 13.8 4.8 0.036 13.8 3.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.6 CCM02855.1 - 0.11 12.3 5.7 0.16 11.8 0.8 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Caudo_TAP PF02413.12 CCM02855.1 - 0.44 10.7 2.9 0.29 11.2 0.7 1.6 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein DUF2968 PF11180.3 CCM02855.1 - 0.58 9.5 6.1 1.1 8.6 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) APG6 PF04111.7 CCM02855.1 - 0.62 9.0 4.1 0.75 8.7 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 CCM02855.1 - 1.1 9.2 6.7 0.34 10.7 1.6 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HR1 PF02185.11 CCM02855.1 - 1.1 9.0 4.1 1.7 8.4 0.5 2.3 2 1 0 2 2 2 0 Hr1 repeat DUF4200 PF13863.1 CCM02855.1 - 1.4 8.8 6.1 0.36 10.7 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2664 PF10867.3 CCM02855.1 - 1.7 9.3 4.7 5.6 7.6 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) Velvet PF11754.3 CCM02856.1 - 2.9e-27 95.5 0.0 2.7e-26 92.4 0.0 2.0 1 1 0 1 1 1 1 Velvet factor Spc24 PF08286.6 CCM02856.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3321 PF11968.3 CCM02857.1 - 1.1e-40 139.6 0.0 1.4e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CCM02857.1 - 7.6e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM02857.1 - 0.00027 21.3 0.0 0.00049 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM02857.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CCM02857.1 - 0.022 15.3 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAD-oxidase_C PF02913.14 CCM02858.1 - 2.1e-55 187.7 0.0 4.3e-55 186.7 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCM02858.1 - 3.1e-26 91.5 0.1 1.1e-25 89.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Telomere_reg-2 PF10193.4 CCM02859.1 - 3.1e-25 88.6 0.0 6.3e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein Gly-zipper_OmpA PF13436.1 CCM02860.1 - 2 8.1 4.1 14 5.3 0.1 2.3 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain 5_nucleotid_C PF02872.13 CCM02861.1 - 9.9e-23 80.8 0.0 1.3e-21 77.2 0.0 2.3 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CCM02861.1 - 6.5e-09 35.4 0.0 2.7e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 CCM02861.1 - 0.0018 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Metallophos_2 PF12850.2 CCM02861.1 - 0.018 14.9 0.0 0.051 13.4 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 CCM02862.1 - 1e-31 109.9 34.2 1e-31 109.9 23.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.6 CCM02862.1 - 0.81 8.9 4.7 0.2 10.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Glyco_hydro_63 PF03200.11 CCM02864.1 - 5.7e-231 768.6 0.0 4.6e-230 765.6 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 CCM02864.1 - 5.7e-06 25.2 0.0 9.3e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 CCM02864.1 - 0.0043 15.8 0.0 0.0073 15.0 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase NYN PF01936.13 CCM02865.1 - 4.3e-20 72.4 0.0 7.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 NYN domain Transcrip_reg PF01709.15 CCM02866.1 - 1.7e-60 204.0 0.0 2e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Sulfate_transp PF00916.15 CCM02867.1 - 5.1e-76 255.3 6.8 9.6e-76 254.4 4.7 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCM02867.1 - 3.4e-30 103.5 4.0 3.4e-30 103.5 2.8 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCM02867.1 - 1.8e-09 37.0 0.0 3.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CCM02867.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 STAS domain WD40 PF00400.27 CCM02868.1 - 7.2e-38 127.1 19.0 4.4e-13 48.5 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat NYN PF01936.13 CCM02869.1 - 2.3e-26 92.8 0.0 3.1e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 NYN domain adh_short PF00106.20 CCM02870.1 - 5.3e-24 85.0 1.7 1.2e-23 83.8 1.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PIN_4 PF13638.1 CCM02870.1 - 2.5e-16 59.9 0.0 5.3e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 PIN domain adh_short_C2 PF13561.1 CCM02870.1 - 2e-13 50.7 0.0 5.4e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM02870.1 - 7.4e-13 48.5 0.5 1.6e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 KR domain EST1_DNA_bind PF10373.4 CCM02870.1 - 7.1e-10 38.5 0.0 1.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain NAAA-beta PF15508.1 CCM02870.1 - 0.11 12.8 0.3 14 6.0 0.0 3.4 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase UCR_14kD PF02271.11 CCM02872.1 - 3.6e-39 132.7 1.2 4.1e-39 132.5 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.16 CCM02873.1 - 1.9e-145 483.8 0.0 2.4e-145 483.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CCM02873.1 - 3.9e-44 150.2 0.0 8.2e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCM02873.1 - 5.2e-11 42.5 0.0 1.2e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CCM02873.1 - 0.00072 18.5 0.1 0.0058 15.5 0.0 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Terpene_synth PF01397.16 CCM02873.1 - 0.034 13.5 0.1 0.06 12.7 0.1 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain DUF1538 PF07556.6 CCM02873.1 - 0.059 12.4 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) Cmc1 PF08583.5 CCM02874.1 - 1.4e-12 47.2 2.0 1.6e-12 46.9 1.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 CCM02874.1 - 0.087 12.2 0.6 0.11 11.8 0.4 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Glyco_hydro_31 PF01055.21 CCM02875.1 - 1.1e-119 400.1 0.2 1.4e-119 399.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCM02875.1 - 1.3e-17 63.3 0.1 3e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like PALP PF00291.20 CCM02876.1 - 3.8e-49 167.5 0.0 5.2e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pyridoxal_deC PF00282.14 CCM02878.1 - 4.2e-63 213.0 0.0 5.7e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CCM02878.1 - 1e-05 24.4 0.0 2.3e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DNA_pol_E_B PF04042.11 CCM02879.1 - 1e-34 119.6 0.0 2.6e-17 62.7 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B Hid1 PF12722.2 CCM02881.1 - 2.7e-139 465.4 0.0 9e-139 463.7 0.0 1.6 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CCM02881.1 - 1e-61 209.0 0.2 1.6e-61 208.3 0.1 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Rad51 PF08423.6 CCM02882.1 - 7.4e-24 84.0 0.0 1.5e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CCM02882.1 - 1.5e-07 31.0 0.1 7.1e-07 28.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 CCM02882.1 - 0.0033 16.5 5.2 0.0099 15.0 0.0 2.4 3 0 0 3 3 3 2 KaiC RecA PF00154.16 CCM02882.1 - 0.0056 15.7 0.0 0.017 14.2 0.0 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 CCM02882.1 - 0.0061 15.4 0.2 0.052 12.4 0.1 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain DUF998 PF06197.8 CCM02883.1 - 0.019 14.2 0.2 0.019 14.2 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF998) Amastin PF07344.6 CCM02883.1 - 0.023 14.2 0.6 0.031 13.8 0.4 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein MIG-14_Wnt-bd PF06664.7 CCM02883.1 - 0.026 13.3 0.2 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Atg8 PF02991.11 CCM02884.1 - 4.7e-52 174.3 0.1 6e-52 173.9 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CCM02884.1 - 1.1e-06 28.7 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 UQ_con PF00179.21 CCM02885.1 - 3.6e-21 75.0 0.0 5.2e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCM02885.1 - 0.06 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain Rubredoxin PF00301.15 CCM02885.1 - 0.077 12.8 0.1 0.26 11.1 0.1 1.9 1 0 0 1 1 1 0 Rubredoxin PRP21_like_P PF12230.3 CCM02886.1 - 1.3e-56 191.6 19.4 1.3e-56 191.6 13.4 2.4 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CCM02886.1 - 1.7e-34 117.1 2.0 1.5e-16 59.8 0.1 3.0 3 0 0 3 3 3 2 Surp module ubiquitin PF00240.18 CCM02886.1 - 6.2e-10 38.3 0.0 1.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCM02886.1 - 3.5e-05 23.3 0.0 9.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Med19 PF10278.4 CCM02886.1 - 4.2 7.0 12.9 0.66 9.6 0.8 3.2 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 CMS1 PF14617.1 CCM02887.1 - 1.5e-75 253.5 0.6 1.9e-75 253.2 0.4 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF3952 PF13130.1 CCM02887.1 - 0.12 12.3 0.2 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) RNase_T PF00929.19 CCM02888.1 - 2e-08 34.7 0.0 3.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease LktC PF06261.6 CCM02889.1 - 0.00078 19.1 0.1 0.92 9.2 0.1 2.3 2 0 0 2 2 2 2 Actinobacillus actinomycetemcomitans leukotoxin activator LktC FAM196 PF15265.1 CCM02889.1 - 1.4 8.0 5.9 1.8 7.6 4.1 1.1 1 0 0 1 1 1 0 FAM196 family Ndc80_HEC PF03801.8 CCM02890.1 - 1.6e-27 95.8 0.0 3.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family Fib_alpha PF08702.5 CCM02890.1 - 0.0073 16.4 4.6 0.0073 16.4 3.2 3.2 2 1 2 4 4 4 3 Fibrinogen alpha/beta chain family Nab1 PF04902.7 CCM02890.1 - 0.41 10.1 4.9 0.81 9.1 0.7 2.4 2 0 0 2 2 2 0 Conserved region in Nab1 Mog1 PF04603.7 CCM02891.1 - 1e-30 106.5 0.0 1.5e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein PaREP1 PF05942.6 CCM02892.1 - 7.1e-05 22.6 0.2 7.1e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family DUF2383 PF09537.5 CCM02892.1 - 0.00011 22.4 4.7 0.013 15.7 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF2383) Orbi_VP5 PF00901.12 CCM02892.1 - 0.22 9.6 6.8 0.056 11.6 2.0 1.9 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 DUF972 PF06156.8 CCM02892.1 - 0.75 10.1 11.3 2.1 8.7 2.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Med9 PF07544.8 CCM02892.1 - 0.88 9.3 12.0 3.6 7.3 1.7 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Cpn60_TCP1 PF00118.19 CCM02894.1 - 9.9e-141 469.6 7.6 1.1e-140 469.4 5.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 CCM02894.1 - 0.0021 17.3 0.1 0.0056 15.9 0.0 1.8 2 0 0 2 2 2 1 Telomere recombination TPR_11 PF13414.1 CCM02895.1 - 1.6e-30 104.5 10.7 7.3e-09 35.1 0.1 6.3 4 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 CCM02895.1 - 4.8e-28 94.7 6.7 0.00021 20.9 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 CCM02895.1 - 1.4e-25 87.8 5.2 2.9e-05 23.4 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCM02895.1 - 1e-22 80.2 28.6 5.3e-07 30.1 0.3 7.0 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCM02895.1 - 2.8e-22 78.8 4.3 1.1e-05 25.7 0.0 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCM02895.1 - 1.1e-17 63.6 8.6 5.6e-06 26.2 0.0 5.5 3 1 3 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 CCM02895.1 - 2.2e-16 58.6 1.3 0.011 15.8 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCM02895.1 - 1.1e-15 56.7 13.7 0.0022 18.4 0.0 8.7 4 1 4 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCM02895.1 - 4.6e-15 54.1 0.3 0.18 11.6 0.1 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCM02895.1 - 5.8e-11 42.0 12.2 0.78 10.3 0.0 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat Apc3 PF12895.2 CCM02895.1 - 1.5e-09 37.8 7.5 0.22 11.6 0.0 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCM02895.1 - 2.9e-07 29.7 10.0 6.1 6.8 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCM02895.1 - 2.8e-06 27.1 13.5 0.003 17.3 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 CCM02895.1 - 2.4e-05 23.5 9.9 0.15 11.0 0.1 4.0 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 CCM02895.1 - 0.0034 17.4 0.3 1.9 8.6 0.0 4.4 3 2 3 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.5 CCM02895.1 - 0.064 12.0 0.0 4.9 5.8 0.0 2.3 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) PPTA PF01239.17 CCM02895.1 - 0.1 11.9 0.0 1.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat SRR1 PF07985.7 CCM02897.1 - 2.7e-19 68.8 0.2 4.8e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 SRR1 UDPG_MGDP_dh_C PF03720.10 CCM02897.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PUA PF01472.15 CCM02898.1 - 4.2e-15 55.2 0.0 7e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 PUA domain CRM1_C PF08767.6 CCM02899.1 - 2e-131 437.6 0.1 2e-131 437.6 0.1 3.7 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CCM02899.1 - 1.4e-42 145.0 8.1 1.3e-41 141.9 5.5 2.8 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 CCM02899.1 - 5.4e-08 32.6 0.0 2.3e-07 30.6 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Kdo PF06293.9 CCM02900.1 - 9.9e-07 28.0 0.0 1.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CCM02900.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 CCM02900.1 - 0.08 12.2 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family MFS_1 PF07690.11 CCM02901.1 - 2.9e-24 85.4 30.1 3.8e-19 68.6 6.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCM02901.1 - 0.37 9.1 16.7 0.51 8.6 1.6 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein Pkinase_Tyr PF07714.12 CCM02902.1 - 5e-39 133.9 0.0 8.1e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM02902.1 - 4.9e-35 120.9 0.0 8.7e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain MFS_1 PF07690.11 CCM02902.1 - 1.5e-13 50.2 29.2 1.5e-13 50.2 20.2 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Kinase-like PF14531.1 CCM02902.1 - 0.0032 16.4 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CCM02903.1 - 1.5e-37 129.0 0.0 3.1e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM02903.1 - 1e-30 106.8 0.0 2.4e-30 105.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 CCM02903.1 - 0.00085 18.3 0.0 0.0018 17.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Dicistro_VP4 PF11492.3 CCM02903.1 - 0.062 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 Zn_clus PF00172.13 CCM02904.1 - 0.00043 20.1 15.8 0.00063 19.6 11.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TGT PF01702.13 CCM02905.1 - 1.6e-18 66.8 0.1 6.4e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase DUF1945 PF09178.5 CCM02905.1 - 0.011 15.5 0.6 0.038 13.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) DUF3684 PF12449.3 CCM02906.1 - 0 1231.4 0.0 0 1231.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 CCM02906.1 - 0.0017 17.9 0.1 0.011 15.3 0.1 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCM02906.1 - 0.038 13.7 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase His_Phos_2 PF00328.17 CCM02907.1 - 3.1e-42 145.1 0.0 4.1e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 CCM02908.1 - 1.2e-55 188.5 0.0 1.9e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02908.1 - 1.7e-18 66.6 0.1 3.2e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM02908.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCM02908.1 - 0.026 13.8 0.3 0.056 12.7 0.2 1.6 1 0 0 1 1 1 0 RIO1 family AAA PF00004.24 CCM02909.1 - 1.3e-40 138.6 0.0 3.4e-40 137.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.4 CCM02909.1 - 1.4e-35 122.2 0.0 2.5e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCM02909.1 - 6e-13 48.4 0.0 2.2e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 CCM02909.1 - 5e-05 23.4 0.0 0.0024 17.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCM02909.1 - 6.7e-05 22.6 0.0 0.00026 20.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCM02909.1 - 0.00073 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CCM02909.1 - 0.0013 17.7 0.0 0.0051 15.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CCM02909.1 - 0.0015 18.5 0.0 0.0059 16.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCM02909.1 - 0.0055 17.5 0.0 0.02 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCM02909.1 - 0.0097 15.6 0.1 0.029 14.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CCM02909.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 CCM02909.1 - 0.016 14.2 0.0 0.038 13.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CCM02909.1 - 0.018 14.1 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CCM02909.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CCM02909.1 - 0.026 14.5 0.0 0.085 12.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CCM02909.1 - 0.041 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 CCM02909.1 - 0.062 13.1 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CCM02909.1 - 0.065 13.5 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.6 CCM02909.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCM02909.1 - 0.12 11.5 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CCM02909.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus ATP-synt_ab PF00006.20 CCM02910.1 - 2.6e-111 370.2 0.0 3.9e-111 369.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Fasciclin PF02469.17 CCM02910.1 - 2.2e-30 105.2 0.2 4.8e-13 49.2 0.0 4.5 4 0 0 4 4 4 4 Fasciclin domain ATP-synt_ab_C PF00306.22 CCM02910.1 - 1.8e-21 76.7 2.3 3.8e-21 75.6 1.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCM02910.1 - 8e-14 51.6 2.9 1.8e-13 50.4 2.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 CCM02910.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCM02910.1 - 0.13 11.9 0.0 5.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain IPPT PF01715.12 CCM02911.1 - 2.9e-50 170.6 0.1 1.2e-28 99.7 0.0 2.7 2 1 0 2 2 2 2 IPP transferase AAA_18 PF13238.1 CCM02911.1 - 3e-05 24.3 0.0 0.0022 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCM02911.1 - 0.00046 21.0 0.0 0.0014 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCM02911.1 - 0.0022 17.4 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCM02911.1 - 0.0092 16.1 0.0 0.047 13.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCM02911.1 - 0.022 14.9 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 CCM02911.1 - 0.025 13.9 0.1 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 CCM02911.1 - 0.094 12.6 0.5 8.9 6.2 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.5 CCM02911.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ribosomal_L18e PF00828.14 CCM02912.1 - 9.1e-22 77.8 0.0 1.6e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PRP38 PF03371.10 CCM02913.1 - 5.8e-62 208.3 1.5 3.5e-61 205.8 1.0 1.9 1 1 0 1 1 1 1 PRP38 family PHD PF00628.24 CCM02914.1 - 1.7e-05 24.4 3.4 1.7e-05 24.4 2.3 1.9 2 0 0 2 2 2 1 PHD-finger BcrAD_BadFG PF01869.15 CCM02915.1 - 4.2e-11 42.6 0.0 1.4e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family PGM_PMM_II PF02879.11 CCM02916.1 - 1.2e-20 73.7 0.0 2.6e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 CCM02916.1 - 9e-20 70.5 0.1 4e-18 65.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CCM02916.1 - 5e-17 61.9 0.1 1e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CCM02916.1 - 0.00013 21.8 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Proteasome PF00227.21 CCM02917.1 - 3.6e-37 127.5 1.0 7.4e-28 97.1 0.1 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 CCM02917.1 - 3.8e-15 54.8 0.1 9.8e-15 53.5 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Orthopox_B11R PF07033.6 CCM02917.1 - 0.47 9.9 2.5 9.9 5.7 0.1 3.0 3 1 0 3 3 3 0 Orthopoxvirus B11R protein Peptidase_C78 PF07910.8 CCM02918.1 - 4.5e-31 107.6 0.0 1.6e-30 105.8 0.0 1.9 2 1 0 2 2 2 1 Peptidase family C78 MAT1 PF06391.8 CCM02919.1 - 1.7e-46 158.3 15.3 2.2e-46 158.0 10.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 VIT1 PF01988.14 CCM02919.1 - 0.046 13.1 2.2 0.079 12.4 1.5 1.4 1 0 0 1 1 1 0 VIT family zf-C3HC4_2 PF13923.1 CCM02919.1 - 0.068 13.2 2.1 0.11 12.5 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCM02919.1 - 0.086 12.5 1.5 0.14 11.8 1.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Med8 PF10232.4 CCM02919.1 - 0.29 10.6 6.0 0.42 10.0 4.1 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 zf-RING_5 PF14634.1 CCM02919.1 - 0.31 10.8 2.1 0.51 10.0 1.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CCM02919.1 - 0.51 10.0 2.7 0.92 9.2 1.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FUSC PF04632.7 CCM02919.1 - 0.56 8.5 11.0 0.75 8.1 7.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bap31 PF05529.7 CCM02919.1 - 0.98 8.8 8.2 1.8 7.9 5.7 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like APG6 PF04111.7 CCM02919.1 - 4 6.4 13.3 5.7 5.8 9.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Pkinase PF00069.20 CCM02920.1 - 2e-62 210.6 0.0 2.7e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LigB PF02900.13 CCM02920.1 - 2.1e-38 131.8 0.0 3.1e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Pkinase_Tyr PF07714.12 CCM02920.1 - 2.9e-28 98.6 0.0 4.1e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM02920.1 - 0.0022 17.0 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2172 PF09940.4 CCM02920.1 - 0.28 9.5 0.0 0.43 8.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) Brix PF04427.13 CCM02921.1 - 6.7e-46 156.3 0.0 8.7e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.8 CCM02921.1 - 0.033 14.0 12.3 0.047 13.5 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.4 CCM02921.1 - 0.11 12.5 14.9 0.23 11.5 10.3 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RNA_pol_3_Rpc31 PF11705.3 CCM02921.1 - 6.6 6.5 20.7 13 5.6 14.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cyto_heme_lyase PF01265.12 CCM02922.1 - 1.9e-76 257.0 1.1 1.4e-75 254.2 0.7 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase MFS_1 PF07690.11 CCM02926.1 - 1.7e-38 132.3 30.8 2.5e-38 131.7 21.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM02926.1 - 2e-18 66.2 7.6 2e-18 66.2 5.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM02927.1 - 1.4e-40 139.0 21.2 1.4e-40 139.0 14.7 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM02927.1 - 9.3e-18 64.0 6.9 9.3e-18 64.0 4.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter YbgT_YccB PF08173.6 CCM02927.1 - 0.081 12.7 3.4 0.092 12.5 0.4 2.7 2 0 0 2 2 2 0 Membrane bound YbgT-like protein NMO PF03060.10 CCM02928.1 - 5.7e-25 88.1 0.2 7.4e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCM02928.1 - 0.011 14.6 0.0 0.014 14.2 0.0 1.2 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain WD40 PF00400.27 CCM02929.1 - 1.1e-20 72.5 0.8 5.5e-06 26.0 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCM02929.1 - 0.00066 18.5 0.0 0.34 9.5 0.0 2.9 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 CCM02929.1 - 0.011 13.9 0.0 0.06 11.4 0.0 2.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 CAP_N PF01213.14 CCM02929.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal LURAP PF14854.1 CCM02930.1 - 0.036 13.7 0.8 0.15 11.8 0.1 2.1 1 1 1 2 2 2 0 Leucine rich adaptor protein TPR_14 PF13428.1 CCM02931.1 - 5e-08 32.9 13.3 5.9 7.8 0.0 10.7 9 2 2 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM02931.1 - 1.1e-06 28.5 4.7 0.65 9.9 0.1 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCM02931.1 - 1.3e-06 27.8 2.9 1.1 8.9 0.1 6.1 5 1 2 7 7 7 2 TPR repeat NRDE-2 PF08424.5 CCM02931.1 - 1e-05 24.6 4.2 0.64 8.8 0.1 4.2 3 1 1 4 4 4 3 NRDE-2, necessary for RNA interference Suf PF05843.9 CCM02931.1 - 1.2e-05 25.1 9.7 5.1e-05 23.1 1.2 4.0 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 CCM02931.1 - 0.0011 19.5 16.4 0.37 11.5 0.0 6.1 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCM02931.1 - 0.0013 18.5 17.6 0.2 11.6 0.1 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat GST_C PF00043.20 CCM02931.1 - 0.031 14.2 0.1 0.11 12.5 0.1 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TPR_17 PF13431.1 CCM02931.1 - 0.034 14.3 4.9 2.6e+02 2.2 0.1 7.2 9 0 0 9 9 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CCM02931.1 - 0.045 13.5 7.9 5.9 6.6 0.3 5.0 6 0 0 6 6 6 0 Mad3/BUB1 homology region 1 HAT PF02184.11 CCM02931.1 - 1.1 9.1 11.9 2.9 7.7 0.1 6.0 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat PPTA PF01239.17 CCM02932.1 - 2.4e-44 146.8 7.5 2.8e-08 32.7 0.6 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat MetW PF07021.7 CCM02932.1 - 0.015 14.7 0.1 1.5 8.1 0.0 2.5 2 1 0 2 2 2 0 Methionine biosynthesis protein MetW FliD_N PF02465.13 CCM02934.1 - 0.037 14.3 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF445 PF04286.7 CCM02934.1 - 0.12 11.9 9.4 0.18 11.2 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Got1 PF04178.7 CCM02935.1 - 3.3e-25 88.4 20.1 4.5e-25 88.0 13.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.3 CCM02935.1 - 7.3 6.7 10.6 2.9 7.9 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) BatA PF07584.6 CCM02936.1 - 0.037 14.2 0.2 0.082 13.1 0.1 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Syndecan PF01034.15 CCM02936.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 CCM02936.1 - 0.18 11.1 0.2 0.18 11.1 0.1 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Herpes_BLLF1 PF05109.8 CCM02936.1 - 0.7 7.7 30.5 1 7.2 21.1 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TMEM154 PF15102.1 CCM02936.1 - 0.85 9.3 7.1 16 5.2 4.9 2.8 1 1 0 1 1 1 0 TMEM154 protein family Lactamase_B PF00753.22 CCM02937.1 - 1.9e-21 76.6 5.7 2.5e-21 76.2 3.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCM02937.1 - 0.059 12.9 0.1 0.079 12.4 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SRP54 PF00448.17 CCM02938.1 - 4.1e-46 156.9 0.2 1.9e-45 154.7 0.1 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CCM02938.1 - 2.2e-39 135.5 0.0 2.8e-38 131.8 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 CCM02938.1 - 1.9e-07 30.7 0.1 4.2e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 CCM02938.1 - 9.2e-07 28.8 0.0 2.8e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 CCM02938.1 - 2.2e-05 23.3 0.1 5.1e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 CCM02938.1 - 0.0028 17.3 0.1 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CCM02938.1 - 0.0058 16.7 0.0 0.031 14.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM02938.1 - 0.012 15.6 0.0 0.39 10.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.1 CCM02938.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 CCM02938.1 - 0.038 13.1 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.10 CCM02938.1 - 0.055 13.1 0.5 0.13 11.9 0.0 1.9 2 1 0 2 2 2 0 NTPase ArsA_ATPase PF02374.10 CCM02938.1 - 0.072 12.1 0.6 1.6 7.7 0.1 2.2 1 1 1 2 2 2 0 Anion-transporting ATPase RRM_1 PF00076.17 CCM02940.1 - 1.7e-66 219.7 0.0 1.8e-18 65.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM02940.1 - 2.5e-53 177.9 0.0 4.8e-13 48.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM02940.1 - 5.3e-28 96.6 0.0 1.8e-07 30.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCM02940.1 - 0.00034 20.3 0.2 10 5.9 0.0 4.8 4 2 0 4 4 4 1 Limkain b1 RRM_2 PF04059.7 CCM02940.1 - 0.00034 20.5 0.0 11 6.1 0.0 4.5 5 0 0 5 5 5 1 RNA recognition motif 2 RRM_3 PF08777.6 CCM02940.1 - 0.031 14.1 0.0 7.4 6.4 0.0 4.2 4 0 0 4 4 4 0 RNA binding motif DNA_pol_B_palm PF14792.1 CCM02941.1 - 5.4e-19 68.2 0.0 1.4e-18 66.9 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 CCM02941.1 - 2.7e-18 65.4 0.0 6e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 CCM02941.1 - 6.8e-12 45.3 0.1 1.5e-10 41.1 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CCM02941.1 - 4e-08 32.6 0.0 9.2e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 CCM02941.1 - 0.0068 16.5 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.3 CCM02941.1 - 0.017 14.9 0.0 0.066 13.1 0.0 1.8 2 0 0 2 2 2 0 Pathogenicity locus Acyl-CoA_dh_1 PF00441.19 CCM02942.1 - 3.3e-24 85.7 0.0 6.2e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCM02942.1 - 2.2e-20 71.8 0.1 6.4e-20 70.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CCM02942.1 - 1.6e-17 64.1 0.0 3e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCM02942.1 - 2.3e-05 24.6 0.1 5.8e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CCM02942.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Nitroreductase PF00881.19 CCM02943.1 - 2e-10 40.7 0.0 2.6e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.11 CCM02944.1 - 1e-51 175.7 47.1 1.3e-48 165.5 33.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCM02944.1 - 1.6e-14 53.0 22.1 2.3e-14 52.5 15.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF373 PF04123.8 CCM02944.1 - 2.4 7.1 12.5 0.016 14.2 1.3 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF373) DUF3554 PF12074.3 CCM02945.1 - 2.5e-44 152.0 7.1 1.9e-42 145.8 0.4 5.0 5 1 2 7 7 7 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 CCM02945.1 - 6.2e-38 128.9 41.8 2e-06 27.9 0.1 15.2 10 4 4 15 15 15 8 HEAT repeats HEAT_EZ PF13513.1 CCM02945.1 - 5.9e-34 115.6 32.1 1.3e-05 25.5 0.1 17.8 14 3 6 20 20 19 11 HEAT-like repeat HEAT PF02985.17 CCM02945.1 - 2.6e-33 111.0 27.0 0.19 11.8 0.0 19.8 21 0 0 21 21 20 8 HEAT repeat CLASP_N PF12348.3 CCM02945.1 - 5.5e-13 48.7 0.0 1.1e-05 24.8 0.0 6.2 5 1 0 6 6 6 3 CLASP N terminal Cnd1 PF12717.2 CCM02945.1 - 2.7e-09 37.1 0.0 0.47 10.2 0.0 7.6 5 2 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CCM02945.1 - 1.9e-08 34.5 0.2 1.5 9.2 0.0 7.6 7 1 2 9 9 9 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 CCM02945.1 - 2.3e-08 32.8 3.5 0.24 9.6 0.1 7.0 9 0 0 9 9 9 2 Adaptin N terminal region NUC173 PF08161.7 CCM02945.1 - 0.016 14.5 0.0 0.13 11.6 0.0 2.7 1 0 0 1 1 1 0 NUC173 domain MMS19_N PF14500.1 CCM02945.1 - 0.04 13.1 3.3 4 6.6 0.0 5.0 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II ATG_C PF09333.6 CCM02945.1 - 0.17 12.0 1.0 10 6.3 0.1 3.1 2 0 0 2 2 2 0 ATG C terminal domain DUF2672 PF10878.3 CCM02945.1 - 0.45 10.2 0.2 1.3 8.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) BRAP2 PF07576.7 CCM02946.1 - 4.4e-18 64.8 0.0 1.5e-15 56.7 0.0 2.4 2 0 0 2 2 2 2 BRCA1-associated protein 2 zf-UBP PF02148.14 CCM02946.1 - 1.6e-16 60.1 3.5 2.8e-16 59.3 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CCM02946.1 - 0.00015 21.5 0.5 0.00015 21.5 0.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCM02946.1 - 0.033 14.2 1.8 0.059 13.4 0.7 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM02946.1 - 0.048 13.3 0.6 0.096 12.4 0.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CCM02946.1 - 0.053 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.14 CCM02946.1 - 2 6.1 9.7 2.7 5.7 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VSG_B PF13206.1 CCM02946.1 - 2.5 7.1 10.7 3.7 6.5 7.4 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF3391 PF11871.3 CCM02946.1 - 3.7 7.7 10.4 5.3 7.2 6.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Rootletin PF15035.1 CCM02946.1 - 5.4 6.9 24.0 5 7.0 8.6 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion polyprenyl_synt PF00348.12 CCM02947.1 - 1.5e-47 161.6 0.0 5.4e-47 159.8 0.0 1.7 1 1 0 1 1 1 1 Polyprenyl synthetase GCHY-1 PF02649.9 CCM02948.1 - 0.19 10.9 1.8 0.26 10.5 1.2 1.1 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 DUF3552 PF12072.3 CCM02949.1 - 0.016 14.4 13.5 0.32 10.1 9.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF390 PF04094.9 CCM02949.1 - 0.12 10.4 16.6 0.16 9.9 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) GAGA_bind PF06217.7 CCM02949.1 - 0.19 11.6 7.6 0.62 9.9 2.4 2.1 1 1 1 2 2 2 0 GAGA binding protein-like family DUF2570 PF10828.3 CCM02949.1 - 0.42 10.2 3.3 2 8.0 2.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Silic_transp PF03842.8 CCM02951.1 - 0.0031 15.6 0.8 0.0052 14.9 0.5 1.3 1 0 0 1 1 1 1 Silicon transporter DUF4131 PF13567.1 CCM02951.1 - 1.2 8.5 9.7 2.6 7.4 2.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1077 PF06417.7 CCM02951.1 - 2.1 7.6 5.0 0.63 9.3 0.8 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1077) DUF3552 PF12072.3 CCM02953.1 - 0.0065 15.6 7.3 0.0065 15.6 5.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) DUF390 PF04094.9 CCM02953.1 - 0.25 9.3 6.6 0.36 8.8 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Mito_carr PF00153.22 CCM02954.1 - 1.4e-29 101.6 0.1 9.6e-14 50.8 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein F-box-like PF12937.2 CCM02955.1 - 2.6e-05 23.8 0.5 7.9e-05 22.2 0.4 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CCM02955.1 - 3.7e-05 23.2 0.6 0.11 12.1 0.2 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM02955.1 - 0.08 12.7 10.0 2.2 8.0 0.2 4.4 4 0 0 4 4 4 0 Leucine rich repeat BTB PF00651.26 CCM02956.1 - 9.9e-08 31.9 0.0 7.9e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain AMP-binding PF00501.23 CCM02957.1 - 1.1e-69 234.8 0.1 1.4e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCM02957.1 - 9e-12 45.7 0.1 4.4e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 CCM02960.1 - 1.4e-77 260.8 0.0 1.3e-76 257.6 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCM02960.1 - 2.6e-10 41.0 0.0 6.1e-09 36.7 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hydrolase PF00702.21 CCM02960.1 - 0.075 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cyclase PF04199.8 CCM02961.1 - 7.8e-29 100.5 0.2 9.5e-29 100.2 0.2 1.1 1 0 0 1 1 1 1 Putative cyclase CytochromB561_N PF09786.4 CCM02967.1 - 0.35 9.2 5.0 0.5 8.7 3.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Sulfate_transp PF00916.15 CCM02968.1 - 2.8e-55 187.3 9.0 2.8e-55 187.3 6.2 2.3 2 2 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCM02968.1 - 2e-25 88.2 5.1 2e-25 88.2 3.5 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCM02968.1 - 3.8e-16 58.5 0.0 7.5e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CCM02968.1 - 1.1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 STAS domain Pkinase PF00069.20 CCM02970.1 - 3.3e-67 226.3 0.0 3.9e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM02970.1 - 1.6e-36 125.7 0.0 2.1e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TP_methylase PF00590.15 CCM02971.1 - 3.6e-17 62.7 0.1 6.3e-17 61.9 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Peptidase_S8 PF00082.17 CCM02972.1 - 8.5e-52 176.0 4.5 1.2e-51 175.5 3.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CCM02972.1 - 2e-14 53.8 0.0 4.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Mito_carr PF00153.22 CCM02973.1 - 7.4e-69 227.5 3.8 2.9e-23 81.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acylphosphatase PF00708.13 CCM02974.1 - 2.6e-17 62.6 0.3 2.7e-17 62.6 0.2 1.0 1 0 0 1 1 1 1 Acylphosphatase Kinesin PF00225.18 CCM02975.1 - 4.2e-56 190.0 0.0 6.2e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain GCHY-1 PF02649.9 CCM02975.1 - 0.0054 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Type I GTP cyclohydrolase folE2 AAA_16 PF13191.1 CCM02975.1 - 0.0073 16.3 0.2 0.021 14.8 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCM02975.1 - 0.091 12.8 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ArsB PF02040.10 CCM02976.1 - 5.4e-22 78.3 22.5 1.7e-11 43.7 4.6 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein SNF2_N PF00176.18 CCM02977.1 - 1.2e-69 234.3 1.2 1.2e-69 234.3 0.8 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM02977.1 - 1.7e-13 50.1 0.1 3.4e-12 46.0 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCM02977.1 - 3.3e-05 23.4 0.0 0.0001 21.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CCM02977.1 - 5.9e-05 22.9 0.0 0.00016 21.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CCM02977.1 - 0.014 15.1 0.2 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain 3HCDH_N PF02737.13 CCM02978.1 - 2.3e-49 167.5 3.5 3.7e-48 163.5 2.4 2.3 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CCM02978.1 - 8.6e-09 35.6 0.3 1.5e-06 28.5 0.0 2.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CCM02978.1 - 0.00039 20.3 0.3 0.00088 19.1 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 CCM02978.1 - 0.00043 20.0 0.3 0.0011 18.7 0.2 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Helicase_C_2 PF13307.1 CCM02979.1 - 3.3e-48 163.8 0.0 6.1e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CCM02979.1 - 1.3e-37 128.8 0.0 1.3e-31 109.2 0.0 3.0 2 1 0 2 2 2 2 DEAD_2 AAA_22 PF13401.1 CCM02979.1 - 0.061 13.4 0.4 0.45 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain RF-1 PF00472.15 CCM02980.1 - 0.076 12.8 0.4 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 RF-1 domain Ribosomal_60s PF00428.14 CCM02980.1 - 9.4 6.7 11.4 0.58 10.5 1.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAD_binding_3 PF01494.14 CCM02981.1 - 2.9e-82 276.5 0.0 9.3e-77 258.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 CCM02981.1 - 1.4e-05 24.1 2.5 3.5e-05 22.8 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CCM02981.1 - 2.8e-05 24.1 0.0 7.3e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM02981.1 - 5.4e-05 22.3 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 CCM02981.1 - 8.2e-05 21.8 2.3 0.00031 19.9 0.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCM02981.1 - 0.00015 20.3 0.4 0.00033 19.2 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 CCM02981.1 - 0.00027 20.8 0.2 0.00098 19.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCM02981.1 - 0.0014 19.0 0.1 0.14 12.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCM02981.1 - 0.0064 15.1 0.1 0.013 14.1 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 CCM02981.1 - 0.0094 14.8 0.5 0.015 14.2 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CCM02981.1 - 0.014 15.4 0.1 0.031 14.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCM02981.1 - 0.097 11.7 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FLILHELTA PF10306.4 CCM02982.1 - 5.7e-09 35.8 0.1 1.2e-08 34.9 0.1 1.6 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 CCM02982.1 - 0.042 14.1 0.1 0.071 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) DUF2689 PF10894.3 CCM02982.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) Glyco_hydro_31 PF01055.21 CCM02984.1 - 1.4e-151 505.2 5.6 2.4e-151 504.5 3.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCM02984.1 - 1e-17 63.7 0.1 2.3e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like F-box-like PF12937.2 CCM02985.1 - 0.025 14.3 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 F-box-like SPOUT_MTase PF02590.12 CCM02986.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Cas_Cas4 PF01930.12 CCM02987.1 - 0.25 11.2 1.5 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF83 BTB PF00651.26 CCM02988.1 - 6.5e-07 29.3 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4519 PF15012.1 CCM02988.1 - 1.7 8.6 4.3 3.3 7.6 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) PAT1 PF09770.4 CCM02988.1 - 2.8 6.0 17.8 4.2 5.4 12.3 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.24 CCM02989.1 - 4.3e-15 56.0 0.0 1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCM02989.1 - 0.01 15.8 0.8 0.033 14.1 0.4 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CCM02989.1 - 0.011 15.8 0.9 0.53 10.4 0.3 2.6 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCM02989.1 - 0.014 14.5 0.1 0.034 13.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 CCM02989.1 - 0.02 14.6 0.1 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCM02989.1 - 0.079 12.8 0.3 2.2 8.1 0.2 2.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCM02989.1 - 0.1 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCM02989.1 - 0.14 11.9 0.2 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 CCM02989.1 - 0.19 11.6 1.7 2.8 7.8 0.1 2.9 2 1 1 3 3 3 0 AAA domain NACHT PF05729.7 CCM02990.1 - 3.4e-11 43.0 0.0 3.9e-09 36.3 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 CCM02990.1 - 3e-07 30.5 0.0 1.8e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CCM02990.1 - 2.1e-05 25.3 0.8 0.00099 19.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CCM02990.1 - 9.9e-05 22.6 0.0 0.00038 20.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCM02990.1 - 0.0003 20.9 0.0 0.0029 17.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CCM02990.1 - 0.00083 18.2 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 CCM02990.1 - 0.0033 17.2 0.7 0.0084 15.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 CCM02990.1 - 0.0046 17.1 0.0 0.023 14.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CCM02990.1 - 0.0095 15.6 0.0 0.034 13.9 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain KAP_NTPase PF07693.9 CCM02990.1 - 0.016 14.2 0.1 4 6.3 0.0 3.4 4 0 0 4 4 4 0 KAP family P-loop domain RNA_helicase PF00910.17 CCM02990.1 - 0.016 15.3 0.0 0.056 13.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 CCM02990.1 - 0.024 14.3 0.0 0.7 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CCM02990.1 - 0.048 13.5 0.0 1 9.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 CCM02990.1 - 0.077 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein FYVE_2 PF02318.11 CCM02990.1 - 0.13 12.1 2.6 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger NTPase_1 PF03266.10 CCM02990.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_PrkA PF08298.6 CCM02990.1 - 0.25 9.9 0.0 0.46 9.1 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain DUF2263 PF10021.4 CCM02992.1 - 3.6e-34 117.9 0.0 4.7e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF4098 PF13345.1 CCM02993.1 - 0.086 12.7 0.6 2.5 8.1 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4098) DUF3733 PF12534.3 CCM02994.1 - 0.0013 17.9 0.7 0.017 14.3 0.2 2.3 2 0 0 2 2 2 1 Leucine-rich repeat containing protein 8 tRNA-synt_2 PF00152.15 CCM02995.1 - 4e-65 219.7 0.0 5.6e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCM02995.1 - 3.6e-12 45.9 0.1 1.4e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF4539 PF15072.1 CCM02995.1 - 0.14 11.8 0.0 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) DUF4098 PF13345.1 CCM02999.1 - 0.00014 21.7 7.9 0.023 14.6 0.5 3.5 1 1 0 2 2 2 2 Domain of unknown function (DUF4098) Evr1_Alr PF04777.8 CCM03000.1 - 3.2e-28 97.4 0.8 4.3e-28 97.0 0.6 1.1 1 0 0 1 1 1 1 Erv1 / Alr family zf-CSL PF05207.8 CCM03000.1 - 0.18 11.3 1.0 9.3 5.8 0.1 2.2 2 0 0 2 2 2 0 CSL zinc finger DPBB_1 PF03330.13 CCM03001.1 - 0.00026 20.9 0.1 0.00033 20.6 0.1 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cpn60_TCP1 PF00118.19 CCM03002.1 - 6.5e-131 437.2 0.0 7.5e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 CCM03002.1 - 0.036 14.1 0.1 0.14 12.2 0.0 2.0 1 1 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor LRR_9 PF14580.1 CCM03003.1 - 0.19 11.2 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat Hce2 PF14856.1 CCM03004.1 - 0.0087 15.9 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor NAD_binding_5 PF07994.7 CCM03005.1 - 2.8e-108 361.8 0.0 3.3e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CCM03005.1 - 1.3e-43 147.3 0.0 2.3e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NIF PF03031.13 CCM03006.1 - 4.4e-34 117.4 0.0 6.5e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Bromodomain PF00439.20 CCM03007.1 - 2.5e-12 46.5 0.1 1.8e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Bromodomain Alpha_E2_glycop PF00943.14 CCM03008.1 - 0.058 12.0 0.0 0.082 11.5 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein DUF3595 PF12166.3 CCM03010.1 - 0.062 12.1 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) zf-C2H2_4 PF13894.1 CCM03011.1 - 8.1e-07 28.9 6.3 0.013 15.8 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM03011.1 - 2.8e-06 27.3 4.4 0.025 14.8 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CCM03011.1 - 1.5e-05 24.9 1.2 0.0061 16.7 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 CCM03011.1 - 0.05 13.9 3.1 0.05 13.9 2.1 2.6 3 0 0 3 3 3 0 Zinc-finger double domain NOA36 PF06524.7 CCM03011.1 - 0.16 11.2 3.4 0.27 10.4 0.1 2.1 2 0 0 2 2 2 0 NOA36 protein RhoGAP PF00620.22 CCM03013.1 - 4.1e-38 130.3 0.0 8.2e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 CCM03013.1 - 3.9e-14 52.8 0.1 2.6e-11 43.6 0.0 2.9 2 0 0 2 2 2 2 RasGEF domain PH PF00169.24 CCM03013.1 - 2.4e-08 34.1 0.2 0.0018 18.4 0.1 2.8 3 0 0 3 3 3 2 PH domain RasGEF_N PF00618.15 CCM03013.1 - 2.8e-06 27.3 0.0 2.6e-05 24.2 0.0 2.8 1 1 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.1 CCM03013.1 - 8.3e-06 25.9 0.1 0.00024 21.2 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain adh_short PF00106.20 CCM03014.1 - 0.003 17.5 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Abhydro_lipase PF04083.11 CCM03015.1 - 7.5e-22 76.4 0.1 1.5e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 CCM03015.1 - 1.2e-16 60.9 0.2 2.3e-16 60.0 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCM03015.1 - 7.6e-09 35.7 1.4 2.2e-08 34.2 1.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM03015.1 - 4.1e-08 33.0 0.1 4.3e-07 29.7 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CCM03015.1 - 0.044 13.1 0.3 0.13 11.6 0.2 1.7 1 1 0 1 1 1 0 Putative esterase FSH1 PF03959.8 CCM03015.1 - 0.06 12.7 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Aldedh PF00171.17 CCM03017.1 - 2.6e-09 35.9 0.1 2.8e-09 35.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 CCM03019.1 - 3.4e-16 59.6 0.0 3.6e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM03019.1 - 3e-09 36.8 0.1 5.1e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM03019.1 - 2.3e-07 30.8 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCM03019.1 - 7.8e-06 25.4 0.0 1.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM03019.1 - 0.0021 18.0 0.6 0.0036 17.3 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding YjeF_N PF03853.10 CCM03019.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Caleosin PF05042.8 CCM03021.1 - 7.8e-55 185.1 0.0 1e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein TMEM213 PF15192.1 CCM03021.1 - 0.023 14.7 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 TMEM213 family LRR_6 PF13516.1 CCM03022.1 - 1.1e-06 28.0 5.2 3.6 7.9 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.1 CCM03022.1 - 0.016 14.9 2.1 23 4.8 0.3 4.1 3 1 0 3 3 3 0 Leucine rich repeat zf-CCHC_2 PF13696.1 CCM03022.1 - 0.051 13.0 0.2 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle LRR_1 PF00560.28 CCM03022.1 - 0.12 12.4 4.2 5.6 7.4 0.1 5.2 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.2 CCM03022.1 - 0.46 10.1 4.8 2.3 7.9 0.0 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CCM03022.1 - 0.61 10.5 7.6 72 4.2 0.0 5.8 7 0 0 7 7 7 0 Leucine rich repeat Glyco_hydro_3 PF00933.16 CCM03024.1 - 9.9e-74 247.9 0.0 1.5e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCM03024.1 - 1.4e-67 227.5 0.1 1.1e-66 224.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCM03024.1 - 6.2e-22 77.3 0.0 1.5e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 CCM03024.1 - 1.2e-11 44.5 0.0 2.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Pkinase PF00069.20 CCM03025.1 - 8.4e-40 136.5 0.0 3.8e-21 75.4 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03025.1 - 9.3e-13 47.8 0.8 0.00046 19.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCM03025.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PrmA PF06325.8 CCM03025.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aldo_ket_red PF00248.16 CCM03026.1 - 1.8e-70 236.9 0.0 2.1e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pro-kuma_activ PF09286.6 CCM03028.1 - 2.8e-30 105.2 0.0 5.1e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM03028.1 - 4e-06 26.1 1.4 5e-06 25.8 0.4 1.6 2 0 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.6 CCM03029.1 - 8.8e-39 132.8 0.0 1.5e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM03029.1 - 7.1e-11 41.7 2.8 1.3e-10 40.8 1.9 1.5 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 CCM03030.1 - 1.3e-38 132.2 0.0 4.6e-38 130.4 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM03030.1 - 2.8e-10 39.8 3.5 2.8e-10 39.8 2.5 2.1 1 1 1 2 2 2 2 Subtilase family GFO_IDH_MocA_C PF02894.12 CCM03031.1 - 0.00025 20.8 1.2 4.4 7.1 0.0 3.9 4 0 0 4 4 4 2 Oxidoreductase family, C-terminal alpha/beta domain Pico_P1A PF02226.11 CCM03031.1 - 0.0024 17.5 0.0 28 4.5 0.0 5.7 3 3 3 6 6 6 1 Picornavirus coat protein (VP4) DUF4602 PF15375.1 CCM03031.1 - 0.014 15.4 0.0 67 3.5 0.0 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4602) DUF1801 PF08818.6 CCM03031.1 - 0.045 13.8 0.0 38 4.4 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DU1801) DUF2799 PF10973.3 CCM03031.1 - 0.1 12.6 5.6 67 3.6 0.0 5.5 7 1 0 7 7 7 0 Protein of unknown function (DUF2799) CopC PF04234.7 CCM03032.1 - 7.6e-08 32.8 5.6 27 5.4 0.0 7.4 5 2 2 7 7 7 0 CopC domain DUF2623 PF11115.3 CCM03032.1 - 0.0011 18.8 0.1 28 4.7 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2623) Hypoth_Ymh PF09509.5 CCM03032.1 - 0.0018 17.8 0.2 51 3.5 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (Hypoth_ymh) DUF1780 PF08682.5 CCM03032.1 - 0.0081 15.6 0.0 6.8 6.0 0.0 3.6 4 1 1 5 5 5 1 Protein of unknown function (DUF1780) Clathrin_lg_ch PF01086.12 CCM03032.1 - 0.25 11.2 0.3 1.8e+02 1.9 0.0 4.0 4 0 0 4 4 4 0 Clathrin light chain Adeno_PX PF05829.7 CCM03032.1 - 4.7 6.7 7.3 14 5.3 5.1 1.8 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Pyr_redox_3 PF13738.1 CCM03033.1 - 1.8e-23 83.6 0.0 2.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCM03033.1 - 1.5e-12 46.5 0.0 4.7e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 CCM03033.1 - 1.2e-10 41.1 0.0 5.8e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CCM03033.1 - 2e-08 33.5 0.2 5.8e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM03033.1 - 0.00012 22.0 0.0 0.00031 20.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCM03033.1 - 0.01 15.6 0.1 0.036 13.8 0.0 1.9 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CCM03033.1 - 0.023 13.5 2.1 0.041 12.7 1.0 1.7 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 CCM03033.1 - 0.08 13.3 0.3 3.1 8.2 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SET PF00856.23 CCM03034.1 - 0.00093 19.5 0.0 0.0085 16.4 0.0 2.2 1 1 0 1 1 1 1 SET domain Pro-kuma_activ PF09286.6 CCM03035.1 - 7.6e-35 120.0 0.1 2.1e-34 118.6 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM03035.1 - 1.3e-08 34.3 3.4 1.3e-08 34.3 2.4 1.7 2 1 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.6 CCM03036.1 - 3.5e-23 82.2 0.0 1.6e-21 76.8 0.0 2.4 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM03036.1 - 7.4e-10 38.4 4.0 2.2e-09 36.8 0.4 2.2 1 1 0 2 2 2 2 Subtilase family SET PF00856.23 CCM03037.1 - 8.4e-08 32.6 0.0 2.6e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 SET domain F-box-like PF12937.2 CCM03038.1 - 0.014 15.1 2.4 0.026 14.2 0.3 2.6 2 1 0 2 2 2 0 F-box-like DUF4032 PF13224.1 CCM03039.1 - 0.049 13.3 0.2 7.9 6.1 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4032) KAT11 PF08214.6 CCM03040.1 - 7.5e-38 130.4 0.0 9.9e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Cullin PF00888.17 CCM03041.1 - 4.2e-189 629.9 15.7 5.8e-189 629.4 10.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCM03041.1 - 7.2e-28 96.2 2.7 2.2e-27 94.6 1.9 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Rrf2 PF02082.15 CCM03041.1 - 0.0018 18.3 0.3 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulator DUF1727 PF08353.5 CCM03041.1 - 0.0047 16.5 1.6 0.039 13.5 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1727) MarR_2 PF12802.2 CCM03041.1 - 0.016 14.8 0.0 0.46 10.1 0.0 2.8 3 0 0 3 3 3 0 MarR family MarR PF01047.17 CCM03041.1 - 0.088 12.5 0.3 6.2 6.6 0.0 2.9 2 0 0 2 2 2 0 MarR family ORC6 PF05460.8 CCM03041.1 - 0.09 11.8 4.7 0.56 9.2 0.1 2.5 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Ubie_methyltran PF01209.13 CCM03042.1 - 5.8e-75 251.3 0.0 7.6e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CCM03042.1 - 5.1e-13 48.8 0.0 7.9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM03042.1 - 7.9e-12 45.5 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM03042.1 - 7.7e-11 41.9 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM03042.1 - 7.8e-10 39.1 0.0 1.9e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM03042.1 - 4.3e-08 33.7 0.0 1.8e-07 31.7 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM03042.1 - 5.7e-08 33.0 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM03042.1 - 0.00028 20.8 0.0 0.00073 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Fcf2 PF08698.6 CCM03043.1 - 1.6e-18 66.5 0.0 5.1e-18 64.9 0.0 1.8 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing CTNNBL PF08216.6 CCM03043.1 - 0.0055 16.2 1.3 0.01 15.3 0.1 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear CDC45 PF02724.9 CCM03043.1 - 0.079 10.9 2.4 0.089 10.8 1.7 1.2 1 0 0 1 1 1 0 CDC45-like protein AF-4 PF05110.8 CCM03043.1 - 0.086 10.6 17.2 0.13 10.0 12.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.7 CCM03043.1 - 0.64 9.6 9.8 0.1 12.2 3.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein adh_short PF00106.20 CCM03044.1 - 4.6e-26 91.7 1.7 7.1e-26 91.1 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM03044.1 - 2.2e-14 53.5 1.1 3.5e-14 52.8 0.8 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM03044.1 - 3.4e-07 30.2 0.1 4.6e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCM03044.1 - 7.5e-05 22.2 0.1 0.00011 21.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CCM03044.1 - 0.00029 19.8 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CCM03044.1 - 0.00071 19.3 0.8 0.0014 18.3 0.2 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 CCM03044.1 - 0.0025 16.9 0.6 0.0067 15.5 0.0 2.1 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2493 PF10686.4 CCM03044.1 - 0.015 14.8 0.1 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2493) PROCN PF08083.6 CCM03045.1 - 1.7e-218 724.9 8.2 1.1e-217 722.3 5.5 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CCM03045.1 - 2.8e-127 422.7 0.5 4.9e-127 421.9 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CCM03045.1 - 2.1e-92 306.7 1.2 5.5e-92 305.3 0.8 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CCM03045.1 - 7.3e-80 265.9 2.2 7.3e-80 265.9 1.5 2.7 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CCM03045.1 - 1.4e-68 228.7 0.0 2.6e-68 227.8 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 CCM03045.1 - 1.3e-43 146.7 0.1 3e-43 145.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 CCM03045.1 - 4.2e-35 120.1 0.0 1.1e-34 118.8 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 CCM03045.1 - 0.0043 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DIRP PF06584.8 CCM03046.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 DIRP MBOAT_2 PF13813.1 CCM03048.1 - 1.6e-19 69.7 1.4 4.1e-19 68.4 1.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family OCD_Mu_crystall PF02423.10 CCM03049.1 - 2.5e-31 108.6 0.9 4.7e-30 104.4 0.6 2.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 CCM03049.1 - 0.09 12.8 0.0 0.45 10.6 0.0 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cuticle_1 PF08140.6 CCM03050.1 - 0.63 9.9 3.9 20 5.1 0.0 3.2 3 0 0 3 3 3 0 Crustacean cuticle protein repeat MBOAT_2 PF13813.1 CCM03052.1 - 1.1e-12 47.8 6.9 4.7e-10 39.4 0.5 2.7 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family MFS_1 PF07690.11 CCM03053.1 - 1.4e-29 102.8 48.6 5.6e-21 74.6 14.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.11 CCM03054.1 - 5.6e-27 94.3 51.5 1.9e-20 72.8 18.3 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily DC_STAMP PF07782.8 CCM03054.1 - 0.095 12.3 1.1 0.54 9.8 0.1 2.3 2 0 0 2 2 2 0 DC-STAMP-like protein TPR_1 PF00515.23 CCM03055.1 - 1.4e-06 27.5 1.7 0.009 15.5 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCM03055.1 - 2.6e-06 27.5 16.5 0.022 15.3 0.2 7.0 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCM03055.1 - 2.7e-06 27.6 5.2 1 9.7 0.0 5.1 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCM03055.1 - 1.8e-05 24.3 15.3 0.0032 17.2 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCM03055.1 - 2.4e-05 23.8 9.0 0.055 13.1 0.0 6.2 5 2 3 8 8 8 2 TPR repeat TPR_8 PF13181.1 CCM03055.1 - 0.00024 20.6 3.7 0.56 10.1 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM03055.1 - 0.0062 17.1 23.6 0.068 13.8 1.0 6.2 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCM03055.1 - 0.052 13.7 3.6 17 5.9 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCM03055.1 - 0.054 13.3 0.8 1.1e+02 3.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCM03055.1 - 0.46 10.4 10.9 0.67 9.9 0.6 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat Mito_fiss_reg PF05308.6 CCM03055.1 - 1 8.6 14.0 0.0081 15.5 3.3 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator TPR_10 PF13374.1 CCM03055.1 - 3.6 7.6 6.3 50 4.0 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat SE PF08491.5 CCM03056.1 - 5.5e-92 307.5 0.0 7e-92 307.1 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 CCM03056.1 - 2.7e-09 36.4 0.1 0.0017 17.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCM03056.1 - 6.5e-09 35.3 0.5 0.00033 19.8 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CCM03056.1 - 0.00025 20.0 0.1 0.0028 16.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 CCM03056.1 - 0.00046 18.9 0.3 0.21 10.1 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.19 CCM03056.1 - 0.0014 17.6 0.3 0.19 10.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CCM03056.1 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCM03056.1 - 0.013 14.5 0.0 0.037 13.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 CCM03056.1 - 0.05 13.3 0.2 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 CCM03056.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 CCM03056.1 - 0.065 13.0 0.0 0.13 12.0 0.1 1.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 CCM03056.1 - 0.13 11.3 0.3 8.9 5.3 0.1 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Chitin_synth_2 PF03142.10 CCM03060.1 - 2.7e-239 794.9 0.2 3.9e-239 794.4 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CCM03060.1 - 2.9e-161 537.9 0.0 3.8e-161 537.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 CCM03060.1 - 8e-16 57.5 3.2 3.2e-15 55.6 1.9 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 CCM03060.1 - 6.5e-15 54.6 0.0 2.3e-09 36.9 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 CCM03060.1 - 1.1e-12 48.2 0.0 7.8e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCM03060.1 - 6.6e-12 45.5 4.4 6.6e-12 45.5 3.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CCM03060.1 - 0.00071 19.2 0.0 0.052 13.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_29 PF13555.1 CCM03060.1 - 0.04 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_21 PF13506.1 CCM03060.1 - 0.094 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 T2SE PF00437.15 CCM03060.1 - 0.11 11.3 0.1 0.43 9.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein YwiC PF14256.1 CCM03060.1 - 4.3 7.4 11.1 0.09 12.8 0.4 2.4 2 0 0 2 2 2 0 YwiC-like protein Pkinase PF00069.20 CCM03064.1 - 5.4e-40 137.1 0.0 6.5e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03064.1 - 8.6e-15 54.4 0.0 1.1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCM03064.1 - 0.0002 20.4 0.1 0.0004 19.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCM03064.1 - 0.0026 16.7 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCM03064.1 - 0.017 14.8 0.5 0.034 13.8 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CCM03064.1 - 0.07 11.9 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase STAG PF08514.6 CCM03065.1 - 6e-29 100.1 0.2 1.2e-27 95.9 0.1 2.8 1 1 1 2 2 2 1 STAG domain HEAT_2 PF13646.1 CCM03065.1 - 1e-05 25.6 1.8 0.0002 21.6 0.2 3.6 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 CCM03065.1 - 0.0057 16.6 1.4 1.4e+02 3.0 0.0 6.0 5 0 0 5 5 5 0 HEAT repeat DUF4200 PF13863.1 CCM03065.1 - 0.029 14.3 2.3 0.074 12.9 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Apc3 PF12895.2 CCM03067.1 - 7.6e-09 35.5 7.8 4e-05 23.6 0.8 1.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CCM03067.1 - 7.8e-09 35.4 0.7 0.0011 19.4 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCM03067.1 - 8.6e-09 34.6 5.2 0.0002 21.0 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCM03067.1 - 1e-07 31.4 5.3 3e-05 23.5 0.2 2.0 1 1 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 CCM03067.1 - 4.2e-07 30.2 4.0 6.9e-07 29.5 2.8 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM03067.1 - 3.1e-06 26.5 1.6 0.061 13.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM03067.1 - 1.2e-05 25.8 8.1 0.00023 21.7 1.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCM03067.1 - 1.7e-05 24.9 1.2 0.061 13.7 0.2 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM03067.1 - 1.8e-05 24.5 2.1 3.4e-05 23.6 1.2 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCM03067.1 - 7.2e-05 22.6 3.5 0.0016 18.4 0.3 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCM03067.1 - 0.0015 18.0 5.6 0.0056 16.2 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCM03067.1 - 0.0025 17.4 5.6 0.01 15.5 0.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCM03067.1 - 0.0051 16.9 2.4 0.0072 16.4 1.6 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat PPR PF01535.15 CCM03067.1 - 0.0059 16.4 1.8 0.17 11.9 0.1 2.8 2 1 1 3 3 3 1 PPR repeat PPR_3 PF13812.1 CCM03067.1 - 0.017 15.3 0.1 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_21 PF09976.4 CCM03067.1 - 0.038 13.9 3.8 0.047 13.6 2.6 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCM03067.1 - 0.083 12.8 0.6 0.89 9.5 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Spore_III_AB PF09548.5 CCM03067.1 - 0.11 12.2 2.7 0.14 11.9 1.8 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Syntaxin PF00804.20 CCM03067.1 - 0.19 11.8 3.0 0.25 11.4 2.0 1.3 1 1 0 1 1 1 0 Syntaxin Metal_resist PF13801.1 CCM03067.1 - 0.2 11.6 2.2 0.34 10.8 1.5 1.4 1 1 0 1 1 1 0 Heavy-metal resistance XhlA PF10779.4 CCM03067.1 - 0.58 10.1 6.8 6.4 6.7 0.2 2.3 1 1 1 2 2 2 0 Haemolysin XhlA Stathmin PF00836.14 CCM03067.1 - 3.1 7.4 10.9 4.9 6.7 7.6 1.3 1 1 0 1 1 1 0 Stathmin family DUF3184 PF11380.3 CCM03068.1 - 0.0049 14.8 1.6 0.016 13.1 0.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3184) Telomerase_RBD PF12009.3 CCM03069.1 - 1.4e-34 118.8 0.4 4.5e-34 117.2 0.2 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CCM03069.1 - 1.2e-11 44.3 0.6 2.3e-10 40.2 0.2 2.7 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GSHPx PF00255.14 CCM03073.1 - 8.2e-43 144.1 0.4 1e-42 143.8 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CCM03073.1 - 1.7e-05 24.5 0.1 4.3e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCM03073.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.5 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 CCM03073.1 - 0.0063 16.5 0.0 0.0095 16.0 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4174) SCO1-SenC PF02630.9 CCM03073.1 - 0.085 12.4 0.1 4.6 6.8 0.0 2.7 2 1 1 3 3 3 0 SCO1/SenC Metallophos PF00149.23 CCM03075.1 - 8.8e-08 31.7 1.6 1.5e-07 31.0 0.2 1.8 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCM03075.1 - 0.00037 20.3 0.0 0.00082 19.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.6 CCM03075.1 - 0.017 13.2 0.2 0.039 12.0 0.0 1.5 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase Cytochrom_C_2 PF01322.15 CCM03078.1 - 0.41 11.1 7.1 1.1 9.8 4.9 1.7 1 0 0 1 1 1 0 Cytochrome C' IncA PF04156.9 CCM03078.1 - 4.8 6.7 10.9 9.7 5.7 7.6 1.4 1 0 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 CCM03079.1 - 1.4e-45 155.7 22.1 2e-45 155.1 15.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM03079.1 - 3.4e-19 68.7 27.2 3.4e-19 68.7 18.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM03080.1 - 2.2e-46 158.4 24.6 2.8e-46 158.0 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM03080.1 - 1e-18 67.1 27.2 1.7e-18 66.4 18.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3669 PF12417.3 CCM03080.1 - 0.081 12.6 0.1 0.47 10.2 0.2 2.0 2 0 0 2 2 2 0 Zinc finger protein FXR1P_C PF12235.3 CCM03081.1 - 0.02 15.0 2.7 0.022 14.8 1.9 1.0 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal tRNA_synt_1c_R2 PF04557.10 CCM03081.1 - 1.3 9.7 5.7 1.9 9.2 4.0 1.5 1 1 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 RRM_1 PF00076.17 CCM03082.1 - 1.2e-15 56.8 0.0 3e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03082.1 - 3.6e-12 46.0 0.0 7.5e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM03082.1 - 1.2e-08 34.6 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TC1 PF15063.1 CCM03082.1 - 0.57 9.7 5.0 0.29 10.7 0.1 3.1 2 1 1 3 3 3 0 Thyroid cancer protein 1 TPR_11 PF13414.1 CCM03084.1 - 2.3e-33 113.6 0.3 2.9e-13 49.2 0.0 6.4 5 1 3 8 8 8 5 TPR repeat TPR_2 PF07719.12 CCM03084.1 - 7.1e-31 103.6 1.9 3.5e-07 29.6 0.0 9.0 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_1 PF00515.23 CCM03084.1 - 2.5e-26 90.1 0.4 2.6e-08 33.0 0.0 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat Apc3 PF12895.2 CCM03084.1 - 1e-22 80.0 0.4 8.6e-09 35.4 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CCM03084.1 - 2.1e-21 75.6 2.3 2.6e-12 46.4 0.0 7.3 8 1 0 9 9 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCM03084.1 - 3e-21 73.5 0.0 3.6e-08 32.6 0.0 7.6 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCM03084.1 - 2.5e-17 63.0 5.4 1.7e-07 31.6 0.0 6.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCM03084.1 - 8.1e-17 59.9 0.7 0.00028 20.8 0.0 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCM03084.1 - 2.8e-15 55.4 5.0 5.5e-05 23.4 0.0 7.3 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCM03084.1 - 2.8e-14 53.1 0.9 0.00089 19.5 0.3 6.4 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCM03084.1 - 7.6e-14 50.3 4.7 0.0019 17.8 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCM03084.1 - 6e-12 45.1 11.7 5e-05 23.4 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCM03084.1 - 1.8e-09 37.1 8.6 0.025 14.5 0.0 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 CCM03084.1 - 3.1e-07 30.1 6.5 1.4 9.5 0.1 5.7 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCM03084.1 - 0.00034 20.3 4.3 0.69 9.8 0.1 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 CCM03084.1 - 0.0022 17.7 1.2 18 5.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCM03084.1 - 0.0048 16.7 1.9 0.7 9.8 0.0 3.8 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 CCM03084.1 - 0.01 16.1 0.3 0.64 10.3 0.0 3.1 2 1 0 2 2 1 0 Bacterial transcriptional activator domain PPR PF01535.15 CCM03084.1 - 0.056 13.4 0.3 15 5.8 0.0 4.0 4 0 0 4 4 3 0 PPR repeat Cohesin_load PF10345.4 CCM03084.1 - 0.27 9.3 0.2 17 3.4 0.0 3.1 3 1 0 3 3 3 0 Cohesin loading factor Mif2_N PF15624.1 CCM03084.1 - 0.65 10.5 4.1 1.4 9.4 2.8 1.5 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Maf1 PF09174.5 CCM03085.1 - 5.4e-37 127.3 0.2 4.3e-30 104.9 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator SCP2 PF02036.12 CCM03086.1 - 1.5e-23 83.0 1.4 1.8e-23 82.7 1.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CCM03086.1 - 0.00053 19.9 0.9 0.00095 19.1 0.4 1.6 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Dynamin_N PF00350.18 CCM03087.1 - 6e-42 143.3 0.0 1.9e-41 141.7 0.0 1.9 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 CCM03087.1 - 1.1e-10 40.7 0.0 8.7e-10 37.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 CCM03087.1 - 0.00055 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCM03087.1 - 0.0038 17.7 0.0 0.0096 16.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 CCM03087.1 - 0.031 14.2 1.9 1 9.3 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 CCM03087.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain DHDPS PF00701.17 CCM03088.1 - 5.9e-42 143.2 0.0 6.8e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 CCM03088.1 - 9.3e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MTS PF05175.9 CCM03088.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain IstB_IS21_ATP PF08483.6 CCM03088.1 - 0.21 11.2 0.4 0.52 10.0 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal Med22 PF06179.7 CCM03089.1 - 2e-16 59.9 1.5 2.9e-16 59.4 1.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex ICL PF00463.16 CCM03089.1 - 0.11 10.6 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family Rad51 PF08423.6 CCM03090.1 - 4e-12 45.5 0.0 7.4e-07 28.3 0.0 3.0 2 1 0 2 2 2 2 Rad51 KaiC PF06745.8 CCM03090.1 - 2.8e-07 29.9 0.0 4.4e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 CCM03090.1 - 7.7e-07 28.7 0.0 2.5e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 CCM03090.1 - 4.3e-05 22.7 0.0 7.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 CCM03090.1 - 0.0065 15.3 0.0 0.045 12.6 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain NB-ARC PF00931.17 CCM03090.1 - 0.036 12.9 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 CCM03090.1 - 0.056 13.4 0.2 0.15 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CCM03090.1 - 0.072 12.7 0.3 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Serinc PF03348.10 CCM03091.1 - 5e-153 509.8 9.7 5.9e-153 509.6 6.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3661 PF12400.3 CCM03091.1 - 0.17 11.9 6.0 0.098 12.7 0.8 2.5 2 0 0 2 2 2 0 Vaculolar membrane protein AAA_11 PF13086.1 CCM03092.1 - 4e-27 95.3 0.0 2.2e-12 47.0 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CCM03092.1 - 3.6e-13 49.5 0.0 1.8e-12 47.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCM03092.1 - 5.4e-12 45.2 0.5 1.4e-11 43.9 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain Helicase_RecD PF05127.9 CCM03092.1 - 0.00018 21.2 0.1 0.00075 19.1 0.1 2.0 1 1 0 1 1 1 1 Helicase DEAD PF00270.24 CCM03092.1 - 0.00032 20.2 0.0 0.0009 18.7 0.0 1.8 2 0 0 2 2 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 CCM03092.1 - 0.00092 19.2 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCM03092.1 - 0.0013 18.9 0.1 0.0039 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CCM03092.1 - 0.0015 18.0 0.1 0.92 8.9 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CCM03092.1 - 0.008 15.1 0.2 0.21 10.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CCM03092.1 - 0.012 15.0 0.0 0.033 13.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.1 CCM03092.1 - 0.017 14.6 0.1 0.049 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 CCM03092.1 - 0.019 15.1 0.1 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CCM03092.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CCM03092.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.16 CCM03092.1 - 0.036 13.3 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain KaiC PF06745.8 CCM03092.1 - 0.046 12.8 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 CCM03092.1 - 0.053 12.9 0.2 0.12 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CCM03092.1 - 0.083 11.7 0.1 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 CCM03092.1 - 0.1 12.2 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CCM03092.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CCM03092.1 - 0.12 11.0 0.2 1.7 7.2 0.0 2.2 2 1 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CCM03092.1 - 0.2 12.4 0.6 0.54 11.0 0.4 1.8 1 1 0 1 1 1 0 AAA domain Pro_isomerase PF00160.16 CCM03093.1 - 1.1e-41 142.5 0.0 1.5e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.15 CCM03094.1 - 5.7e-129 430.2 0.1 6.9e-129 429.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCM03094.1 - 5.9e-13 48.4 0.1 1e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 CCM03094.1 - 0.0079 15.7 0.1 0.035 13.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 CCM03094.1 - 0.016 14.3 0.2 2 7.5 0.0 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Ras PF00071.17 CCM03094.1 - 0.055 12.8 0.0 6.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Ras family F_actin_cap_B PF01115.12 CCM03095.1 - 1.1e-103 345.6 0.0 1.3e-103 345.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit NAD_binding_9 PF13454.1 CCM03095.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding THUMP PF02926.12 CCM03096.1 - 1.5e-11 44.3 0.2 2.2e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 THUMP domain Adipokin_hormo PF06377.6 CCM03096.1 - 0.0041 17.2 0.2 2.6 8.2 0.0 3.2 2 1 0 2 2 2 2 Adipokinetic hormone Cwf_Cwc_15 PF04889.7 CCM03096.1 - 0.14 11.8 0.4 0.21 11.2 0.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HD PF01966.17 CCM03097.1 - 2.6e-05 24.2 0.4 6e-05 23.0 0.3 1.7 1 1 0 1 1 1 1 HD domain Zip PF02535.17 CCM03098.1 - 1.6e-47 162.0 15.0 2e-40 138.7 3.8 2.5 2 1 0 2 2 2 2 ZIP Zinc transporter NUDIX PF00293.23 CCM03099.1 - 4.7e-13 48.9 0.1 6.8e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain HLH PF00010.21 CCM03100.1 - 1.5e-06 27.8 0.1 3e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4604 PF15377.1 CCM03101.1 - 5.6e-23 81.9 16.4 7.2e-23 81.5 11.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Med13_C PF06333.7 CCM03101.1 - 0.16 10.4 0.9 0.19 10.2 0.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Asp PF00026.18 CCM03103.1 - 2.3e-71 240.6 2.1 2.8e-71 240.3 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM03103.1 - 6e-06 26.3 2.2 1.3e-05 25.2 0.6 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal WD40 PF00400.27 CCM03104.1 - 3.3e-12 45.7 7.6 0.047 13.6 0.0 5.9 5 2 0 5 5 5 4 WD domain, G-beta repeat SH3_9 PF14604.1 CCM03105.1 - 0.00021 20.7 0.1 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCM03105.1 - 0.0031 16.8 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain VSP PF03302.8 CCM03105.1 - 0.14 10.7 0.7 0.2 10.2 0.5 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2749 PF10907.3 CCM03105.1 - 1.1 9.1 5.8 0.34 10.8 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) SIR2 PF02146.12 CCM03106.1 - 1.2e-27 96.8 0.2 4e-27 95.0 0.0 2.0 2 1 0 2 2 2 1 Sir2 family TPP_enzyme_M PF00205.17 CCM03106.1 - 0.033 13.9 0.1 8.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain SH3_9 PF14604.1 CCM03107.1 - 7.6e-05 22.2 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF318 PF03773.8 CCM03108.1 - 0.015 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Predicted permease HTH_37 PF13744.1 CCM03108.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3650 PF12368.3 CCM03108.1 - 0.16 11.4 0.3 0.29 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) DUF350 PF03994.9 CCM03108.1 - 0.96 9.2 6.2 13 5.6 2.7 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Pex14_N PF04695.8 CCM03108.1 - 8.4 6.4 11.8 19 5.2 1.5 3.8 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region tRNA-synt_2b PF00587.20 CCM03110.1 - 3e-45 153.8 0.2 4.6e-45 153.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCM03110.1 - 4.6e-17 61.7 0.0 1e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CCM03110.1 - 9.1e-16 57.4 0.0 3e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 CCM03110.1 - 6.1e-11 42.0 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Hepar_II_III PF07940.8 CCM03112.1 - 2.9e-08 33.6 0.2 5.9e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 Heparinase II/III-like protein FAM70 PF14967.1 CCM03112.1 - 0.059 12.5 0.4 0.11 11.6 0.3 1.4 1 0 0 1 1 1 0 FAM70 protein Thiolase_N PF00108.18 CCM03113.1 - 2.2e-72 243.2 0.2 4.5e-72 242.1 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCM03113.1 - 1.8e-18 66.1 2.4 7.4e-18 64.1 1.7 2.0 1 1 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCM03113.1 - 0.0022 17.4 0.4 0.041 13.3 0.2 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CCM03113.1 - 0.09 12.4 2.0 0.29 10.8 0.0 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TatD_DNase PF01026.16 CCM03114.1 - 1.3e-42 145.7 0.0 2.8e-42 144.7 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase FNIP PF05725.7 CCM03114.1 - 0.16 11.9 0.3 0.3 11.0 0.2 1.4 1 0 0 1 1 1 0 FNIP Repeat Filament PF00038.16 CCM03115.1 - 0.1 12.0 33.0 0.97 8.8 7.8 2.6 1 1 1 2 2 2 0 Intermediate filament protein GAS PF13851.1 CCM03115.1 - 0.17 11.0 29.0 0.33 10.1 10.1 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 CCM03115.1 - 0.87 9.5 19.8 4 7.4 0.4 4.7 4 0 0 4 4 4 0 bZIP transcription factor Prominin PF05478.6 CCM03115.1 - 2.5 5.5 9.4 0.55 7.6 2.9 2.1 1 1 1 2 2 2 0 Prominin Zn_clus PF00172.13 CCM03116.1 - 1.5e-07 31.1 10.7 2.8e-07 30.3 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCM03116.1 - 3.3e-05 22.9 0.1 6.8e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TB2_DP1_HVA22 PF03134.14 CCM03117.1 - 3.3e-23 81.2 6.1 5.9e-23 80.4 4.2 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GtrA PF04138.9 CCM03117.1 - 0.092 12.6 1.8 0.23 11.4 0.3 2.0 1 1 0 2 2 2 0 GtrA-like protein TPR_11 PF13414.1 CCM03118.1 - 3.3e-11 42.6 0.2 1.5e-08 34.1 0.0 2.3 1 1 1 2 2 2 2 TPR repeat F-box-like PF12937.2 CCM03118.1 - 1.8e-07 30.7 0.0 4.4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.12 CCM03118.1 - 4.1e-07 29.4 0.3 0.005 16.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat F-box PF00646.28 CCM03118.1 - 2.1e-05 24.0 0.1 0.00014 21.4 0.0 2.5 2 0 0 2 2 2 1 F-box domain TPR_1 PF00515.23 CCM03118.1 - 2.7e-05 23.5 0.2 0.031 13.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCM03118.1 - 3.6e-05 24.2 0.8 0.03 14.9 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM03118.1 - 0.004 17.6 1.7 10 7.0 0.1 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat LRR_6 PF13516.1 CCM03118.1 - 0.0064 16.4 0.3 7.6 6.9 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeat TPR_12 PF13424.1 CCM03118.1 - 0.0065 16.3 0.2 0.18 11.7 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCM03118.1 - 0.17 12.2 0.2 29 5.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec3_C PF09763.4 CCM03119.1 - 1.1e-163 546.1 2.2 1.4e-163 545.7 1.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Glyco_transf_21 PF13506.1 CCM03119.1 - 2e-23 82.5 0.8 6.5e-18 64.6 0.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 21 Sec3-PIP2_bind PF15277.1 CCM03119.1 - 2.1e-19 69.1 0.0 5.4e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Glyco_tranf_2_3 PF13641.1 CCM03119.1 - 1.8e-18 67.1 0.1 3.3e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CCM03119.1 - 1.7e-05 24.5 0.2 5.4e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Vps52 PF04129.7 CCM03119.1 - 0.0011 17.6 1.3 0.0046 15.5 0.3 2.0 2 0 0 2 2 2 1 Vps52 / Sac2 family WD40 PF00400.27 CCM03120.1 - 7.5e-16 57.3 7.5 0.0014 18.4 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Homeobox PF00046.24 CCM03121.1 - 2e-14 52.9 0.4 2e-14 52.9 0.3 2.1 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CCM03121.1 - 0.051 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 CCM03122.1 - 7.3e-13 47.9 1.9 7.8e-13 47.8 0.5 1.7 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CCM03122.1 - 0.0006 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Octopine_DH PF02317.12 CCM03122.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F-box-like PF12937.2 CCM03123.1 - 1.2e-08 34.4 0.3 2.7e-08 33.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like PB1 PF00564.19 CCM03124.1 - 2.3e-05 23.9 0.0 4.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Aldo_ket_red PF00248.16 CCM03125.1 - 4.5e-49 166.7 0.0 5.2e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ApbA_C PF08546.6 CCM03126.1 - 1.3e-34 118.8 0.1 2.4e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CCM03126.1 - 9.3e-24 83.5 0.1 6.6e-23 80.8 0.1 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 CCM03127.1 - 2.2e-39 135.1 48.2 8.2e-39 133.3 33.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM03127.1 - 1.8e-14 53.1 50.1 5.1e-13 48.3 10.5 3.1 1 1 1 3 3 3 3 Sugar (and other) transporter Transglut_core2 PF13369.1 CCM03128.1 - 9.7e-16 57.6 0.0 1.6e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.6 CCM03128.1 - 4.2e-15 55.4 0.0 8.2e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.2 CCM03128.1 - 4.7e-06 26.2 0.6 1.8e-05 24.3 0.4 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM03128.1 - 0.00093 18.7 0.0 0.0028 17.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain Nucleopor_Nup85 PF07575.8 CCM03128.1 - 0.17 10.0 0.1 0.27 9.3 0.0 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin O-FucT PF10250.4 CCM03129.1 - 6.3e-13 48.5 0.0 3e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase TPT PF03151.11 CCM03130.1 - 1.9e-07 30.8 13.2 1.9e-07 30.8 9.1 2.8 2 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CCM03130.1 - 0.0034 17.4 30.3 0.021 14.8 6.0 2.6 2 1 1 3 3 3 2 EamA-like transporter family COPI_assoc PF08507.5 CCM03130.1 - 0.012 15.2 0.2 0.012 15.2 0.2 2.4 2 1 0 2 2 2 0 COPI associated protein Condensation PF00668.15 CCM03131.1 - 0.061 12.1 0.0 0.36 9.6 0.0 2.0 2 0 0 2 2 2 0 Condensation domain AATase PF07247.7 CCM03131.1 - 0.066 11.7 0.0 0.097 11.2 0.0 1.3 1 0 0 1 1 1 0 Alcohol acetyltransferase DUF1741 PF08427.5 CCM03132.1 - 2.4e-40 138.5 0.2 5.1e-40 137.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) GDC-P PF02347.11 CCM03133.1 - 3e-180 599.5 0.1 5.7e-172 572.2 0.0 2.7 2 1 1 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CCM03133.1 - 5.4e-05 22.1 0.4 0.00043 19.1 0.1 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCM03133.1 - 9e-05 21.7 0.1 0.00019 20.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase PPR_2 PF13041.1 CCM03134.1 - 6.5e-20 70.8 3.0 0.0018 18.2 0.1 7.8 7 2 3 10 10 10 5 PPR repeat family PPR_3 PF13812.1 CCM03134.1 - 8.3e-10 38.1 6.7 0.41 11.0 0.0 7.7 10 0 0 10 10 10 3 Pentatricopeptide repeat domain PPR PF01535.15 CCM03134.1 - 1.5e-08 34.0 7.4 0.16 11.9 0.1 8.1 8 1 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 CCM03134.1 - 3.1e-08 32.9 3.4 0.019 14.4 0.1 5.4 6 0 0 6 6 6 2 PPR repeat SecE PF00584.15 CCM03135.1 - 4.1e-15 55.1 0.1 4.6e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Vps51 PF08700.6 CCM03137.1 - 6.6e-14 51.5 0.2 3e-13 49.3 0.1 2.2 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 CCM03137.1 - 0.032 14.1 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1751 PF08551.5 CCM03138.1 - 1.8e-28 98.7 3.6 4.7e-28 97.4 2.5 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.10 CCM03138.1 - 0.00015 21.3 8.5 0.00024 20.6 5.9 1.3 1 0 0 1 1 1 1 Der1-like family DUF1754 PF08555.5 CCM03139.1 - 1.6e-13 51.0 10.4 1.6e-13 51.0 7.2 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.1 CCM03139.1 - 0.0014 17.8 0.1 0.0021 17.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) BNIP3 PF06553.7 CCM03139.1 - 0.022 14.1 4.6 0.029 13.7 3.2 1.1 1 0 0 1 1 1 0 BNIP3 Menin PF05053.8 CCM03139.1 - 0.15 10.2 8.4 0.17 10.0 5.9 1.0 1 0 0 1 1 1 0 Menin PP2C_C PF07830.8 CCM03139.1 - 0.26 11.4 1.6 0.96 9.5 0.0 2.4 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain IncA PF04156.9 CCM03139.1 - 1.1 8.7 3.9 1.6 8.2 2.7 1.2 1 0 0 1 1 1 0 IncA protein CPSF73-100_C PF11718.3 CCM03139.1 - 1.7 7.9 5.4 2 7.7 3.8 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF2956 PF11169.3 CCM03139.1 - 3.7 7.5 12.6 0.26 11.2 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) U79_P34 PF03064.11 CCM03139.1 - 4.3 6.7 11.6 5 6.5 8.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Tombus_P33 PF08500.5 CCM03139.1 - 7.1 6.3 6.0 20 4.9 4.1 1.7 1 1 0 1 1 1 0 Tombusvirus p33 RFXA_RFXANK_bdg PF15289.1 CCM03139.1 - 9.2 6.4 9.3 5.4 7.2 5.2 1.5 1 1 1 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Peptidase_M3 PF01432.15 CCM03140.1 - 5.8e-132 440.9 0.0 7.3e-132 440.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 CCM03140.1 - 0.2 11.7 0.1 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Effector protein Homeobox PF00046.24 CCM03141.1 - 1.4e-13 50.2 0.1 4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCM03141.1 - 5.8e-09 35.5 1.3 1.1e-08 34.5 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 CCM03141.1 - 0.045 12.8 0.1 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Mating_C PF12737.2 CCM03142.1 - 9.2e-09 34.6 16.2 9.2e-09 34.6 11.2 2.0 1 1 0 2 2 2 1 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.6 CCM03142.1 - 5.7e-08 32.3 0.0 1.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Mating_N PF12731.2 CCM03142.1 - 0.00011 22.0 0.1 0.00024 20.8 0.1 1.6 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox PF00046.24 CCM03142.1 - 0.0078 15.8 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain HTH_29 PF13551.1 CCM03142.1 - 0.037 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix DUF1793 PF08760.6 CCM03143.1 - 1.2e-58 197.8 0.3 2.1e-58 196.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) FAD_binding_7 PF03441.9 CCM03144.1 - 5.3e-95 317.7 0.2 7.4e-94 314.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CCM03144.1 - 9.3e-39 132.8 0.1 1.7e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 CCM03144.1 - 0.042 14.0 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Universal stress protein family Phosducin PF02114.11 CCM03146.1 - 0.022 13.4 0.3 0.04 12.6 0.2 1.4 1 1 0 1 1 1 0 Phosducin Geminin PF07412.7 CCM03146.1 - 0.044 13.4 1.5 0.13 11.9 0.9 1.7 2 0 0 2 2 2 0 Geminin Thioredoxin PF00085.15 CCM03146.1 - 0.048 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF2959 PF11172.3 CCM03146.1 - 0.076 12.7 1.3 0.1 12.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF2167 PF09935.4 CCM03146.1 - 0.13 11.0 0.3 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Kinesin-relat_1 PF12711.2 CCM03146.1 - 0.14 12.6 3.1 0.32 11.4 2.0 1.7 1 1 1 2 2 2 0 Kinesin motor Fib_alpha PF08702.5 CCM03146.1 - 0.2 11.7 1.4 1.5 8.9 0.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family eRF1_1 PF03463.10 CCM03147.1 - 1.9e-44 150.4 0.0 3.1e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 CCM03147.1 - 7.4e-23 80.9 0.0 1.4e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 CCM03147.1 - 7.7e-18 65.1 0.0 1.1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 OMPdecase PF00215.19 CCM03148.1 - 1.1e-72 244.0 0.0 1.3e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TruD PF01142.13 CCM03149.1 - 2e-40 138.6 0.0 3.1e-39 134.7 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) DUF3628 PF12300.3 CCM03149.1 - 0.51 10.3 23.7 1.3 9.0 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) RAM PF15320.1 CCM03149.1 - 8.3 6.7 15.6 17 5.7 1.0 2.9 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein TruD PF01142.13 CCM03150.1 - 1.1e-06 27.5 0.0 2.3e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) MFS_1 PF07690.11 CCM03151.1 - 1.1e-30 106.6 26.4 4.2e-30 104.6 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM03151.1 - 1.7e-06 26.8 4.5 1.7e-06 26.8 3.1 2.2 1 1 0 2 2 2 1 Sugar (and other) transporter DUF791 PF05631.9 CCM03151.1 - 0.00087 18.0 0.6 0.0015 17.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) DUF1129 PF06570.6 CCM03151.1 - 0.17 11.2 0.9 0.42 9.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Gly_transf_sug PF04488.10 CCM03152.1 - 1.2e-20 73.8 0.2 2e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CCM03152.1 - 0.00068 18.2 2.6 0.055 11.9 0.8 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 CCM03152.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PIN_4 PF13638.1 CCM03153.1 - 3.7e-24 85.3 0.7 5.8e-24 84.7 0.5 1.3 1 0 0 1 1 1 1 PIN domain DUF2369 PF10179.4 CCM03153.1 - 0.03 13.4 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) CTD_bind PF04818.8 CCM03154.1 - 0.0011 19.1 0.0 0.0031 17.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 CCM03154.1 - 0.011 15.8 0.1 0.091 12.9 0.0 2.4 2 1 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 DAP3 PF10236.4 CCM03154.1 - 0.04 12.8 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ribosomal_L6 PF00347.18 CCM03155.1 - 6.1e-30 103.5 3.8 3.4e-16 59.4 0.9 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 ICMT PF04140.9 CCM03156.1 - 1.2e-05 25.4 0.1 2.7e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF423 PF04241.10 CCM03156.1 - 0.16 11.8 5.9 0.11 12.4 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF423) GTP_EFTU PF00009.22 CCM03157.1 - 3.3e-46 157.1 0.0 5.1e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CCM03157.1 - 5.7e-17 61.3 0.0 1.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCM03157.1 - 3.6e-12 45.9 0.0 3.4e-10 39.6 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCM03157.1 - 2.3e-06 27.6 0.0 5.9e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCM03157.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase IFT43 PF15305.1 CCM03158.1 - 3.2 7.7 10.5 2.2 8.2 5.9 1.7 1 1 0 1 1 1 0 Intraflagellar transport protein 43 ADH_N PF08240.7 CCM03159.1 - 1e-30 105.6 0.3 1.7e-30 104.9 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM03159.1 - 3.1e-19 68.8 0.0 5.8e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM03159.1 - 4.2e-05 24.4 0.0 9.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CCM03159.1 - 0.0059 16.1 0.1 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 CCM03159.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 CCM03159.1 - 0.04 14.4 0.0 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Meth_synt_2 PF01717.13 CCM03160.1 - 1.2e-143 478.0 0.0 1.4e-139 464.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCM03160.1 - 9.4e-123 409.4 0.0 3.6e-110 368.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain DUF2985 PF11204.3 CCM03162.1 - 1.5e-26 91.9 1.5 2.5e-26 91.2 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF4349 PF14257.1 CCM03162.1 - 3.4 6.8 4.5 22 4.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Apt1 PF10351.4 CCM03163.1 - 2.4e-74 250.8 0.5 2.4e-74 250.8 0.3 1.9 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 CCM03163.1 - 6.4e-57 193.0 0.0 1.4e-56 191.9 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 CCM03163.1 - 5.5e-39 133.5 0.0 1.2e-38 132.5 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CCM03163.1 - 7.7e-20 71.2 0.0 1.9e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CCM03163.1 - 8.8e-12 45.3 0.0 3e-11 43.6 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DNA_pol_E_B PF04042.11 CCM03164.1 - 4.3e-41 140.4 0.4 7.1e-41 139.7 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B UPF0183 PF03676.9 CCM03165.1 - 1.5e-42 145.5 0.0 6.2e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) HAD_2 PF13419.1 CCM03166.1 - 3.6e-20 72.9 0.0 4.2e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCM03166.1 - 3e-07 30.0 0.0 6.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCM03166.1 - 5.8e-07 30.1 0.0 7.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L6e PF01159.14 CCM03167.1 - 6.8e-30 103.4 0.2 2.1e-29 101.9 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L6e 60KD_IMP PF02096.15 CCM03167.1 - 1.1e-18 67.6 0.0 1.8e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_L6e_N PF03868.10 CCM03167.1 - 5e-09 35.9 1.4 8.3e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain adh_short PF00106.20 CCM03169.1 - 3.1e-20 72.7 0.5 4.1e-20 72.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM03169.1 - 2.6e-06 27.2 0.3 4.2e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM03169.1 - 0.0024 17.6 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM03169.1 - 0.0039 17.2 0.6 0.0084 16.1 0.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 CCM03169.1 - 0.0045 16.0 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.21 CCM03169.1 - 0.014 14.8 0.1 0.057 12.9 0.0 2.1 2 1 0 2 2 2 0 Zinc-binding dehydrogenase NAD_Gly3P_dh_N PF01210.18 CCM03169.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 CCM03169.1 - 0.042 13.5 0.2 0.075 12.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CCM03169.1 - 0.054 13.9 0.1 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CCM03169.1 - 0.081 12.3 0.1 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.10 CCM03169.1 - 0.089 12.3 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein VWA_2 PF13519.1 CCM03169.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain TrkA_N PF02254.13 CCM03169.1 - 0.13 12.2 0.1 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain CRCB PF02537.10 CCM03170.1 - 1.6e-32 111.8 17.1 2.4e-19 69.3 3.8 2.3 2 0 0 2 2 2 2 CrcB-like protein PGG PF13962.1 CCM03170.1 - 0.024 14.2 2.3 0.088 12.4 1.6 2.1 1 1 0 1 1 1 0 Domain of unknown function SNARE_assoc PF09335.6 CCM03171.1 - 9.8e-15 54.8 4.4 9.8e-15 54.8 3.1 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein CK_II_beta PF01214.13 CCM03172.1 - 1.3e-76 256.2 0.0 2.3e-76 255.4 0.0 1.4 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ribosomal_L36e PF01158.13 CCM03172.1 - 6.3e-37 125.4 2.6 9.8e-37 124.8 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L36e BTB PF00651.26 CCM03173.1 - 5.4e-07 29.5 0.0 8.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain FAM196 PF15265.1 CCM03174.1 - 0.0018 17.5 18.3 0.0018 17.5 12.7 3.9 2 1 1 4 4 4 1 FAM196 family Reo_sigmaC PF04582.7 CCM03174.1 - 0.77 8.8 45.1 0.061 12.4 5.3 4.8 1 1 3 5 5 5 0 Reovirus sigma C capsid protein Filament PF00038.16 CCM03174.1 - 3 7.2 72.6 0.012 15.0 4.7 5.6 1 1 2 4 4 4 0 Intermediate filament protein BLOC1_2 PF10046.4 CCM03174.1 - 3.6 7.7 36.7 0.075 13.1 0.8 6.8 5 2 1 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoO PF09769.4 CCM03174.1 - 3.9 7.1 9.7 2.4 7.8 0.4 4.0 4 0 0 4 4 4 0 Apolipoprotein O TPR_MLP1_2 PF07926.7 CCM03174.1 - 9.8 5.9 78.8 0.012 15.3 4.0 7.5 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein Mito_carr PF00153.22 CCM03175.1 - 4.5e-65 215.4 3.3 1.4e-23 82.4 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 CCM03175.1 - 4.2e-46 153.2 20.5 1.5e-09 37.3 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat HET PF06985.6 CCM03175.1 - 5.1e-17 62.3 2.1 1.1e-14 54.7 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) EF-hand_7 PF13499.1 CCM03175.1 - 0.00053 20.0 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair PD40 PF07676.7 CCM03175.1 - 0.00085 18.9 1.0 4.1 7.1 0.0 4.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 CCM03175.1 - 0.0011 18.4 3.8 0.6 9.4 0.5 3.4 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain EF-hand_1 PF00036.27 CCM03175.1 - 0.0028 16.8 1.0 0.0083 15.3 0.1 2.2 2 0 0 2 2 2 1 EF hand Nup160 PF11715.3 CCM03175.1 - 0.0062 14.7 0.9 8.3 4.4 0.0 3.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 EF-hand_6 PF13405.1 CCM03175.1 - 0.02 14.7 0.9 0.045 13.6 0.1 2.0 2 0 0 2 2 1 0 EF-hand domain Nucleoporin_N PF08801.6 CCM03175.1 - 0.15 10.7 0.0 6.1 5.4 0.0 2.5 2 1 0 3 3 3 0 Nup133 N terminal like EF-hand_5 PF13202.1 CCM03175.1 - 0.18 11.2 1.0 0.35 10.2 0.1 1.9 2 0 0 2 2 2 0 EF hand Piwi PF02171.12 CCM03176.1 - 5.8e-78 261.9 0.0 9.5e-78 261.2 0.0 1.4 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 CCM03176.1 - 4.6e-16 57.9 0.0 1.3e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 CCM03176.1 - 6.8e-11 41.6 0.0 1.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Histidinol_dh PF00815.15 CCM03177.1 - 9.3e-177 587.7 1.2 1.3e-176 587.2 0.8 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 CCM03177.1 - 9.4e-27 92.4 0.3 2e-26 91.4 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CCM03177.1 - 1.3e-08 34.9 0.1 5e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 CCM03177.1 - 0.065 13.1 0.1 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Transket_pyr PF02779.19 CCM03178.1 - 9e-48 162.1 0.1 1.7e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCM03178.1 - 2.6e-39 133.9 0.2 8.7e-39 132.2 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Ser_hydrolase PF06821.8 CCM03178.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase adh_short PF00106.20 CCM03179.1 - 5.1e-31 107.8 1.4 7.9e-31 107.2 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM03179.1 - 1.1e-16 61.3 0.1 1.4e-16 61.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM03179.1 - 2.2e-14 53.5 1.8 3.6e-14 52.8 1.2 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCM03179.1 - 1.5e-06 28.3 0.2 2.8e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM03179.1 - 2e-06 27.4 0.0 3.6e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM03179.1 - 0.046 12.4 0.0 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.5 CCM03179.1 - 0.075 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 CCM03179.1 - 0.15 10.8 0.2 1.2 7.9 0.2 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Amidohydro_2 PF04909.9 CCM03180.1 - 8.8e-28 97.6 0.2 1.7e-27 96.6 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase Abhydrolase_6 PF12697.2 CCM03181.1 - 2.3e-06 27.6 0.0 1e-05 25.5 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM03181.1 - 0.041 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Iso_dh PF00180.15 CCM03182.1 - 2.8e-70 237.0 0.1 2e-64 217.7 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase TPPII_N PF12583.3 CCM03183.1 - 0.74 9.9 3.6 1.8 8.6 0.3 2.2 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Clat_adaptor_s PF01217.15 CCM03184.1 - 2.4e-45 153.7 1.3 2.7e-45 153.5 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RNase_T PF00929.19 CCM03185.1 - 2.5e-16 60.3 0.0 9.2e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Exonuclease TRAM_LAG1_CLN8 PF03798.11 CCM03186.1 - 5.8e-32 110.8 25.7 5.8e-32 110.8 17.8 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CCM03186.1 - 6.3e-11 41.6 0.1 1.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Peptidase_S10 PF00450.17 CCM03187.1 - 3.9e-77 260.1 6.8 6.6e-76 256.1 1.9 2.4 2 1 1 3 3 3 2 Serine carboxypeptidase HSA PF07529.8 CCM03188.1 - 0.0089 15.7 0.3 0.022 14.5 0.2 1.6 1 0 0 1 1 1 1 HSA GAS PF13851.1 CCM03188.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ORC6 PF05460.8 CCM03188.1 - 0.52 9.3 0.0 0.52 9.3 0.0 3.2 2 1 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) BLUF PF04940.7 CCM03189.1 - 0.035 13.8 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Sensors of blue-light using FAD Syntaxin-6_N PF09177.6 CCM03189.1 - 0.062 13.7 0.1 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF3740 PF12548.3 CCM03189.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Sulfatase protein Histone PF00125.19 CCM03190.1 - 1.7e-13 50.4 0.0 2.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 eIF-4B PF06273.6 CCM03190.1 - 0.16 10.7 7.0 0.18 10.4 4.9 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B GRP PF07172.6 CCM03190.1 - 0.29 11.6 18.3 0.43 11.0 12.7 1.2 1 0 0 1 1 1 0 Glycine rich protein family CAF-1_p150 PF11600.3 CCM03191.1 - 0.0044 16.4 19.5 0.0044 16.4 13.5 2.8 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1180 PF06679.7 CCM03192.1 - 0.41 10.5 2.7 0.47 10.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RTA1 PF04479.8 CCM03194.1 - 1.3e-06 28.0 2.8 2e-06 27.4 1.9 1.3 1 1 0 1 1 1 1 RTA1 like protein Claudin_3 PF06653.6 CCM03194.1 - 1.8 8.2 6.2 0.2 11.3 1.0 1.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like G-alpha PF00503.15 CCM03195.1 - 8.2e-60 202.5 0.0 4.5e-48 163.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit E3_binding PF02817.12 CCM03195.1 - 0.088 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 e3 binding domain Peptidase_M24 PF00557.19 CCM03196.1 - 2.4e-39 135.0 0.0 4.1e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCM03196.1 - 4e-18 66.1 0.0 1.7e-17 64.1 0.0 2.1 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain PX PF00787.19 CCM03198.1 - 1.2e-23 82.9 0.1 1.6e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 PX domain Trs65 PF12735.2 CCM03199.1 - 1.8e-26 93.1 0.4 1.9e-22 79.9 0.0 3.2 2 1 0 2 2 2 2 TRAPP trafficking subunit Trs65 Mito_carr PF00153.22 CCM03200.1 - 1.3e-27 95.2 2.9 1.3e-14 53.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 CCM03201.1 - 0.0085 15.7 0.0 0.03 14.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like La PF05383.12 CCM03201.1 - 0.025 14.3 0.4 6 6.7 0.0 3.2 3 1 0 3 3 3 0 La domain Arrestin_N PF00339.24 CCM03202.1 - 5.4e-10 39.2 0.1 7.5e-09 35.5 0.0 2.5 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCM03202.1 - 2.2e-09 37.5 6.8 4e-06 26.9 5.5 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 CCM03202.1 - 3.6e-05 23.3 0.0 7.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Pyridoxal_deC PF00282.14 CCM03203.1 - 9e-20 70.4 0.0 1.9e-19 69.3 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CCM03203.1 - 1.3e-08 34.0 0.0 5.3e-08 31.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CCM03203.1 - 1.7e-06 27.3 0.7 2.9e-06 26.5 0.5 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CUE PF02845.11 CCM03205.1 - 4.6e-07 29.1 0.0 7.9e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain Clathrin_lg_ch PF01086.12 CCM03205.1 - 0.0063 16.4 1.1 0.0096 15.8 0.7 1.4 1 0 0 1 1 1 1 Clathrin light chain ATP-synt_C PF00137.16 CCM03207.1 - 5.7e-28 96.6 27.4 5.5e-17 61.4 4.9 2.8 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 CCM03207.1 - 0.066 13.4 1.0 5 7.4 0.4 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.19 CCM03207.1 - 0.57 9.8 5.9 0.49 10.0 0.8 2.9 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF373 PF04123.8 CCM03207.1 - 1.2 8.0 7.5 1.9 7.3 5.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Cation_efflux PF01545.16 CCM03207.1 - 1.5 7.7 9.7 0.11 11.5 1.1 2.8 1 1 0 2 2 2 0 Cation efflux family Arf PF00025.16 CCM03208.1 - 4.7e-37 126.9 0.0 1.6e-36 125.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CCM03208.1 - 1e-12 47.5 0.0 6.5e-08 31.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CCM03208.1 - 7.4e-09 36.1 0.0 1.1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CCM03208.1 - 2.6e-07 30.1 0.0 4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CCM03208.1 - 8.6e-06 25.0 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCM03208.1 - 2.8e-05 23.4 0.0 5e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCM03208.1 - 9e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CCM03208.1 - 0.0027 17.9 0.1 0.0052 17.0 0.1 1.5 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 CCM03208.1 - 0.0028 17.1 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CCM03208.1 - 0.022 14.9 0.0 0.058 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 CCM03208.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_23 PF13476.1 CCM03208.1 - 0.023 15.0 0.6 0.041 14.2 0.4 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CCM03208.1 - 0.024 14.2 0.1 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 CCM03208.1 - 0.028 13.8 0.0 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 CCM03208.1 - 0.044 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CCM03208.1 - 0.057 12.4 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain SRP54 PF00448.17 CCM03208.1 - 0.062 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 CCM03208.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 CCM03208.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Voltage_CLC PF00654.15 CCM03209.1 - 2.1e-87 293.4 34.0 2.1e-87 293.4 23.5 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CCM03209.1 - 6.8e-13 48.1 0.1 3.7e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.20 CCM03211.1 - 2.3e-13 49.8 0.0 1.1e-11 44.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03211.1 - 0.057 12.4 0.0 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase_Tyr PF07714.12 CCM03212.1 - 3e-45 154.3 0.0 4.2e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM03212.1 - 9.6e-44 149.4 0.0 1.8e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CCM03212.1 - 2.8e-07 29.8 0.0 4.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCM03212.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3414 PF11894.3 CCM03212.1 - 0.17 8.7 0.0 0.23 8.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) Syja_N PF02383.13 CCM03213.1 - 2.3e-64 217.2 0.0 4.8e-64 216.1 0.0 1.6 1 1 0 1 1 1 1 SacI homology domain Pkinase PF00069.20 CCM03214.1 - 3e-08 33.1 0.0 5.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03214.1 - 3.3e-05 23.1 0.0 6.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NTP_transf_2 PF01909.18 CCM03214.1 - 0.0001 22.5 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CCM03214.1 - 0.023 14.6 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase TFIIE_beta PF02186.10 CCM03215.1 - 5.2e-05 23.1 0.8 0.00015 21.6 0.2 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain LSM PF01423.17 CCM03216.1 - 1.5e-18 66.0 0.0 1.8e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain HEAT_EZ PF13513.1 CCM03217.1 - 1.2e-19 70.1 12.3 2.2e-08 34.3 0.0 10.1 8 2 3 11 11 11 2 HEAT-like repeat HEAT_2 PF13646.1 CCM03217.1 - 1.4e-16 60.5 10.8 3.8e-05 23.8 0.0 7.5 3 2 5 8 8 7 5 HEAT repeats HEAT PF02985.17 CCM03217.1 - 5.7e-16 57.1 14.2 0.00025 20.8 0.0 11.5 12 1 1 13 13 13 2 HEAT repeat IBN_N PF03810.14 CCM03217.1 - 1.4e-13 50.5 1.8 1.6e-12 47.1 0.0 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 CCM03217.1 - 5.3e-09 35.5 7.7 0.0024 17.6 0.0 6.5 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CCM03217.1 - 0.0024 17.2 0.0 2 7.7 0.0 4.2 2 1 2 4 4 4 1 CLASP N terminal Adaptin_N PF01602.15 CCM03217.1 - 0.027 12.7 0.2 9.8 4.3 0.0 3.2 2 1 0 2 2 2 0 Adaptin N terminal region Lon_C PF05362.8 CCM03218.1 - 8.1e-65 217.9 0.1 1.4e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CCM03218.1 - 2.8e-23 82.5 0.0 5.6e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CCM03218.1 - 3.6e-14 52.9 0.0 7.7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 CCM03218.1 - 5.8e-10 39.0 0.0 3.1e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCM03218.1 - 3.2e-07 30.4 0.0 9.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCM03218.1 - 2.7e-06 27.4 1.0 3e-05 24.0 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain ChlI PF13541.1 CCM03218.1 - 5.6e-06 25.8 0.0 1.7e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 CCM03218.1 - 4.8e-05 23.5 0.5 0.013 15.5 0.0 3.7 2 2 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CCM03218.1 - 8.9e-05 23.2 0.0 0.00053 20.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CCM03218.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 CCM03218.1 - 0.0015 18.3 0.0 0.0041 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCM03218.1 - 0.0036 16.7 0.0 0.011 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCM03218.1 - 0.0039 16.2 0.0 0.047 12.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 CCM03218.1 - 0.005 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CCM03218.1 - 0.0086 15.8 0.0 0.026 14.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CCM03218.1 - 0.01 15.7 0.1 3.1 7.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 CCM03218.1 - 0.018 13.7 0.0 0.059 12.0 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 CCM03218.1 - 0.026 14.8 0.0 0.1 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCM03218.1 - 0.027 14.3 0.0 0.083 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CCM03218.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CCM03218.1 - 0.1 12.8 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.22 CCM03218.1 - 0.11 12.7 0.1 0.8 9.9 0.0 2.3 2 1 0 3 3 2 0 ABC transporter AAA_21 PF13304.1 CCM03218.1 - 0.2 11.5 0.7 1.7 8.5 0.0 2.6 2 1 1 3 3 3 0 AAA domain Parvo_NS1 PF01057.12 CCM03218.1 - 0.21 10.4 0.0 0.45 9.3 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 CCM03218.1 - 3.5 7.9 0.0 3.5 7.9 0.0 2.5 2 1 0 2 2 1 0 AAA domain Glyco_hydro_3 PF00933.16 CCM03219.1 - 1e-54 185.6 0.0 1.4e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCM03219.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Phage_lysis PF03245.8 CCM03219.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Amidohydro_3 PF07969.6 CCM03220.1 - 2.9e-73 247.3 0.7 3.5e-73 247.1 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 CCM03220.1 - 2e-07 30.9 0.0 7.8e-05 22.4 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 CCM03220.1 - 4.3e-05 23.2 0.0 0.00014 21.5 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CCM03220.1 - 0.0084 16.1 0.3 0.69 9.8 0.1 2.5 2 0 0 2 2 2 1 Amidohydrolase DSPc PF00782.15 CCM03221.1 - 3.4e-22 78.4 0.0 1.6e-21 76.2 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 CCM03221.1 - 0.0095 16.2 0.0 0.035 14.4 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 CCM03221.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF159 PF02586.9 CCM03223.1 - 2.3e-50 170.9 0.0 3.6e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Bromo_TP PF07524.8 CCM03224.1 - 1e-07 31.5 0.1 1.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated eIF-5a PF01287.15 CCM03225.1 - 4.3e-25 87.4 0.1 6.3e-25 86.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CCM03225.1 - 1.6e-05 24.4 0.7 3.7e-05 23.2 0.5 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CCM03225.1 - 0.0055 16.5 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain LIM PF00412.17 CCM03226.1 - 8.2e-22 77.0 22.4 1.2e-11 44.4 5.6 2.2 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 CCM03226.1 - 0.00046 20.0 16.2 1.1 9.2 0.5 4.3 4 0 0 4 4 4 4 Zinc ribbon domain zf-ribbon_3 PF13248.1 CCM03226.1 - 0.0016 17.5 19.3 0.099 11.8 0.3 4.5 4 0 0 4 4 4 3 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CCM03226.1 - 0.013 15.2 28.1 0.07 12.9 4.4 4.1 2 2 2 4 4 4 0 Transposase zinc-ribbon domain DUF2616 PF11077.3 CCM03226.1 - 0.031 13.7 3.4 1.8 8.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) UPF0547 PF10571.4 CCM03226.1 - 0.26 10.9 0.0 0.26 10.9 0.0 3.5 4 1 0 4 4 4 0 Uncharacterised protein family UPF0547 Ribosomal_S27 PF01599.14 CCM03226.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.8 2 0 0 2 2 2 0 Ribosomal protein S27a Elf1 PF05129.8 CCM03226.1 - 3.5 7.3 11.9 0.46 10.2 0.5 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 CCM03226.1 - 4.1 6.7 11.3 0.18 11.1 1.1 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Lar_restr_allev PF14354.1 CCM03226.1 - 8.6 6.7 17.5 3.1 8.1 3.9 3.1 2 2 0 2 2 2 0 Restriction alleviation protein Lar PIH1 PF08190.7 CCM03227.1 - 8.8e-29 100.9 0.0 1.4e-26 93.7 0.0 2.8 2 1 0 2 2 2 2 pre-RNA processing PIH1/Nop17 DAHP_synth_1 PF00793.15 CCM03228.1 - 4.6e-92 307.5 0.1 5.7e-92 307.2 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DAHP_synth_2 PF01474.11 CCM03228.1 - 0.078 11.3 0.2 0.47 8.7 0.1 1.9 1 1 0 1 1 1 0 Class-II DAHP synthetase family FAD-oxidase_C PF02913.14 CCM03228.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain zf-RanBP PF00641.13 CCM03229.1 - 0.054 12.6 4.7 0.098 11.7 3.2 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Adenylsucc_synt PF00709.16 CCM03230.1 - 1.9e-160 534.1 0.0 2.2e-160 533.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase VWA_2 PF13519.1 CCM03231.1 - 5.4e-14 52.6 0.1 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 CCM03231.1 - 4e-11 41.4 15.2 0.00035 19.8 0.1 3.7 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 CCM03231.1 - 1.5e-05 24.7 0.0 3.4e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Ssl1-like Actin PF00022.14 CCM03232.1 - 1.8e-156 520.4 0.0 2.1e-156 520.3 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CCM03232.1 - 0.071 13.5 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CRAL_TRIO PF00650.15 CCM03233.1 - 5.4e-35 120.2 0.0 7.9e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCM03233.1 - 1.3e-14 54.0 1.7 1.3e-14 54.0 1.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain EMG1 PF03587.9 CCM03234.1 - 8.5e-76 253.7 0.0 1.1e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UPRTase PF14681.1 CCM03235.1 - 2.6e-78 261.9 0.0 3e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CCM03235.1 - 8.7e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CoA_binding_2 PF13380.1 CCM03235.1 - 0.04 14.0 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain LNS2 PF08235.8 CCM03235.1 - 0.092 12.3 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Cpn60_TCP1 PF00118.19 CCM03236.1 - 7.1e-135 450.3 10.8 8.3e-135 450.1 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PMT PF02366.13 CCM03237.1 - 6.8e-78 261.4 16.5 6.8e-78 261.4 11.5 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCM03237.1 - 1.2e-47 161.8 0.2 2.3e-47 160.9 0.1 1.5 1 0 0 1 1 1 1 MIR domain DUF1240 PF06836.7 CCM03237.1 - 5.8 7.2 6.2 7.8 6.8 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) Cyclin_N PF00134.18 CCM03238.1 - 8.5e-12 44.7 0.1 5.4e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 CCM03238.1 - 0.0006 19.5 1.0 0.0059 16.4 0.3 2.3 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 CCM03238.1 - 0.0078 16.1 4.6 0.057 13.3 0.3 2.6 2 1 0 2 2 2 1 Cyclin, C-terminal domain Ldh_1_N PF00056.18 CCM03239.1 - 5e-42 143.0 0.0 7.1e-42 142.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCM03239.1 - 7.7e-41 139.7 0.0 1.4e-40 138.8 0.0 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CCM03239.1 - 0.0025 16.5 0.0 0.0035 16.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 CCM03239.1 - 0.072 12.4 0.1 0.63 9.3 0.0 2.1 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase WGG PF10273.4 CCM03240.1 - 2.7e-28 97.8 0.1 5.3e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF3994 PF13159.1 CCM03240.1 - 0.014 15.6 0.3 0.02 15.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3994) RRP7 PF12923.2 CCM03240.1 - 0.28 11.2 0.0 0.28 11.2 0.0 2.3 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Trypan_PARP PF05887.6 CCM03240.1 - 0.56 10.0 4.8 0.87 9.4 3.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Clp1 PF06807.9 CCM03241.1 - 3.4e-10 40.0 0.0 6.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CCM03241.1 - 1.1e-08 34.8 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCM03241.1 - 0.00037 20.4 0.6 0.00081 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCM03241.1 - 0.0004 19.9 0.0 0.0011 18.4 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family Arch_ATPase PF01637.13 CCM03241.1 - 0.00059 19.6 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 CCM03241.1 - 0.0074 16.4 0.0 0.069 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CCM03241.1 - 0.012 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Nop25 PF09805.4 CCM03241.1 - 0.013 15.5 2.0 0.022 14.8 1.4 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) AAA_16 PF13191.1 CCM03241.1 - 0.036 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 CCM03241.1 - 0.037 12.9 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 CCM03241.1 - 0.054 13.6 0.1 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase MSP1_C PF07462.6 CCM03241.1 - 0.068 11.5 0.2 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CobU PF02283.11 CCM03241.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ATP_bind_1 PF03029.12 CCM03241.1 - 0.19 11.2 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ebola_NP PF05505.7 CCM03241.1 - 0.31 9.0 3.1 0.4 8.6 2.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein p450 PF00067.17 CCM03242.1 - 2.3e-51 174.7 0.9 5.6e-51 173.5 0.6 1.6 1 1 0 1 1 1 1 Cytochrome P450 YdjC PF04794.7 CCM03242.1 - 0.035 13.5 0.3 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 YdjC-like protein p450 PF00067.17 CCM03243.1 - 6.4e-12 44.7 0.0 6.8e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RA PF00788.18 CCM03244.1 - 1.6e-14 54.1 0.0 3.5e-11 43.4 0.0 3.5 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain His_Phos_1 PF00300.17 CCM03245.1 - 8.3e-14 51.9 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Meth_synt_2 PF01717.13 CCM03246.1 - 6.2e-11 41.8 0.0 0.00049 19.1 0.0 2.8 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCM03246.1 - 0.028 13.7 0.0 2.7 7.1 0.0 2.6 3 0 0 3 3 3 0 Cobalamin-independent synthase, N-terminal domain F-box-like PF12937.2 CCM03247.1 - 2.5e-07 30.2 1.8 6.4e-07 29.0 1.3 1.7 1 0 0 1 1 1 1 F-box-like CBFD_NFYB_HMF PF00808.18 CCM03248.1 - 2.4e-16 59.5 3.0 5.5e-16 58.3 2.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCM03248.1 - 1.3e-08 34.8 0.0 1.8e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 CCM03248.1 - 0.001 18.8 1.1 0.003 17.3 0.0 2.0 2 0 0 2 2 2 1 CENP-S associating Centromere protein X TAF PF02969.12 CCM03248.1 - 0.1 12.5 0.2 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TIP49 PF06068.8 CCM03249.1 - 1.9e-173 576.7 0.0 2.2e-173 576.5 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CCM03249.1 - 3.6e-10 40.1 0.1 1.2e-06 28.7 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCM03249.1 - 8.4e-09 34.8 0.0 4.2e-07 29.2 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCM03249.1 - 1.7e-07 31.3 0.0 2.3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CCM03249.1 - 1.1e-05 25.1 0.1 0.006 16.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCM03249.1 - 1.2e-05 25.4 0.2 0.058 13.5 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCM03249.1 - 0.00026 20.6 0.3 0.001 18.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 CCM03249.1 - 0.001 19.0 0.1 0.0024 17.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCM03249.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCM03249.1 - 0.0073 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCM03249.1 - 0.0076 15.3 0.5 0.019 14.1 0.1 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CCM03249.1 - 0.0081 16.0 0.0 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCM03249.1 - 0.011 16.6 0.0 0.031 15.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 CCM03249.1 - 0.011 15.6 0.0 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CCM03249.1 - 0.02 14.0 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCM03249.1 - 0.024 14.1 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 CCM03249.1 - 0.058 13.6 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain TFIID-31kDa PF02291.10 CCM03249.1 - 0.064 13.0 0.0 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit NACHT PF05729.7 CCM03249.1 - 0.074 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 CCM03249.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CCM03249.1 - 0.16 11.8 0.0 1 9.1 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit p450 PF00067.17 CCM03251.1 - 2e-62 211.2 0.0 2e-61 207.9 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM03252.1 - 1e-09 37.4 0.0 3.3e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF3692 PF12469.3 CCM03252.1 - 0.033 14.4 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein p450 PF00067.17 CCM03253.1 - 9.3e-45 152.9 0.0 1e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 CCM03254.1 - 1.3e-27 95.1 0.8 4.2e-13 48.5 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CCM03254.1 - 8e-27 93.4 0.1 1.2e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 CCM03254.1 - 9.3e-11 40.9 0.1 9.9e-05 21.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 CCM03254.1 - 3.4e-07 30.0 0.3 3.7e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 CCM03254.1 - 3e-05 23.6 0.0 0.00068 19.2 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 CCM03254.1 - 0.0061 15.9 0.0 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Pirin_C PF05726.8 CCM03254.1 - 0.011 15.8 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Pirin C-terminal cupin domain Cupin_4 PF08007.7 CCM03254.1 - 0.013 14.7 0.1 0.27 10.4 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein ARD PF03079.9 CCM03254.1 - 0.025 14.5 0.0 0.22 11.4 0.0 2.3 3 0 0 3 3 3 0 ARD/ARD' family FdtA PF05523.6 CCM03254.1 - 0.035 13.5 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 WxcM-like, C-terminal cNMP_binding PF00027.24 CCM03254.1 - 0.086 12.6 0.0 0.62 9.9 0.0 2.3 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain DUF3682 PF12446.3 CCM03255.1 - 0.035 14.4 5.5 0.041 14.1 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Cupin_2 PF07883.6 CCM03257.1 - 1.1e-30 104.9 0.6 3.8e-15 55.1 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CCM03257.1 - 6.3e-28 97.0 0.1 4.6e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 CCM03257.1 - 4.6e-12 45.1 0.2 0.00011 21.4 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 CCM03257.1 - 7.2e-08 32.2 0.2 5.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 CCM03257.1 - 4.3e-06 26.4 0.0 9.1e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_6 PF12852.2 CCM03257.1 - 0.0016 18.1 0.0 0.39 10.2 0.0 2.5 1 1 1 2 2 2 1 Cupin ARD PF03079.9 CCM03257.1 - 0.0039 17.1 0.1 0.44 10.4 0.0 2.6 3 0 0 3 3 3 1 ARD/ARD' family 3-HAO PF06052.7 CCM03257.1 - 0.0093 15.3 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.7 CCM03257.1 - 0.017 14.3 0.1 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Cupin superfamily protein Pirin_C PF05726.8 CCM03257.1 - 0.027 14.5 0.0 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Pirin C-terminal cupin domain Cupin_8 PF13621.1 CCM03257.1 - 0.058 12.8 0.0 0.5 9.8 0.0 2.3 1 1 0 1 1 1 0 Cupin-like domain GPI PF06560.6 CCM03257.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) cNMP_binding PF00027.24 CCM03257.1 - 0.16 11.8 0.2 1.6 8.6 0.0 2.4 3 0 0 3 3 2 0 Cyclic nucleotide-binding domain Terpene_synth_C PF03936.11 CCM03258.1 - 1.9e-15 56.8 0.0 2.3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HEAT_EZ PF13513.1 CCM03260.1 - 0.06 13.8 0.1 4.3 7.9 0.0 2.8 2 1 1 3 3 3 0 HEAT-like repeat Alpha-L-AF_C PF06964.7 CCM03261.1 - 8.9e-32 110.2 0.1 1.4e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 CCM03262.1 - 2.1e-99 333.1 23.8 2.4e-99 332.9 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM03262.1 - 2e-27 95.8 45.1 3.8e-21 75.1 14.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CCM03262.1 - 0.00024 20.8 0.9 0.063 13.0 0.0 3.4 3 0 0 3 3 3 1 MFS_1 like family DUF791 PF05631.9 CCM03262.1 - 0.0066 15.1 1.3 0.0066 15.1 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TRI12 PF06609.8 CCM03262.1 - 0.087 10.9 8.0 0.012 13.8 1.5 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DEAD PF00270.24 CCM03263.1 - 7.4e-38 129.6 0.0 7.4e-36 123.1 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM03263.1 - 1.8e-21 75.7 0.0 3.4e-20 71.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM03263.1 - 0.0024 17.7 0.0 0.012 15.4 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCM03263.1 - 0.08 13.0 0.3 4.7 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF726 PF05277.7 CCM03264.1 - 0.00015 20.7 0.1 0.00018 20.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Ribosomal_60s PF00428.14 CCM03264.1 - 2 8.8 7.3 2 8.8 4.6 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein DUF155 PF02582.9 CCM03266.1 - 1.4e-46 158.5 0.0 2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 CCM03266.1 - 0.032 14.4 0.2 0.3 11.3 0.0 2.6 3 1 0 3 3 3 0 Uncharacterised protein family UPF0449 Pkinase PF00069.20 CCM03267.1 - 5.4e-68 228.9 0.0 6.3e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03267.1 - 9.8e-28 96.9 0.0 1.3e-27 96.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM03267.1 - 1.2e-06 27.7 0.0 1.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CCM03267.1 - 0.00061 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CCM03267.1 - 0.0039 16.2 0.3 0.0099 14.9 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM03267.1 - 0.004 16.9 0.3 1 9.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family TcdB_toxin_midN PF12256.3 CCM03267.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region YukC PF10140.4 CCM03267.1 - 0.064 11.8 0.0 0.084 11.4 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC NTF2 PF02136.15 CCM03268.1 - 2.1e-27 95.8 0.1 3.3e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 CCM03268.1 - 3.9e-06 26.3 0.0 6.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM03268.1 - 0.0014 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03268.1 - 0.047 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rad52_Rad22 PF04098.10 CCM03269.1 - 3.1e-59 199.1 0.0 4.8e-59 198.5 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein NDUFA12 PF05071.11 CCM03270.1 - 2.2e-11 44.1 0.5 6.8e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WW PF00397.21 CCM03271.1 - 0.005 16.6 0.2 0.17 11.7 0.0 2.8 2 0 0 2 2 2 1 WW domain Adaptin_binding PF10199.4 CCM03272.1 - 0.29 11.3 4.3 0.32 11.2 3.0 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 MRI PF15325.1 CCM03272.1 - 5.4 8.0 12.4 6.5 7.7 8.4 1.3 1 1 0 1 1 1 0 Modulator of retrovirus infection WW PF00397.21 CCM03273.1 - 0.0055 16.5 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 WW domain Peptidase_C14 PF00656.17 CCM03274.1 - 2.3e-31 109.4 0.0 2.7e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 CCM03275.1 - 8.9e-38 130.3 0.0 1.2e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 CCM03275.1 - 0.0021 17.9 0.2 0.031 14.1 0.2 2.3 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain Afi1 PF07792.7 CCM03276.1 - 2e-37 128.4 0.0 6e-37 126.8 0.0 1.8 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 CCM03276.1 - 2.8e-32 110.7 0.0 6.2e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CCM03276.1 - 0.00049 18.6 0.0 0.014 13.8 0.0 2.7 2 1 1 3 3 3 1 Transport protein Avl9 DUF2347 PF09804.4 CCM03276.1 - 0.03 13.6 0.0 0.71 9.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Coatomer_WDAD PF04053.9 CCM03278.1 - 2.3e-139 465.0 0.0 7.5e-139 463.3 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 CCM03278.1 - 1.5e-94 316.9 0.0 2.3e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CCM03278.1 - 2.8e-57 188.6 12.1 1.7e-10 40.3 0.2 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 CCM03278.1 - 0.0067 14.6 4.4 0.089 10.9 0.0 3.2 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 CCM03278.1 - 0.047 13.2 0.0 12 5.5 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.1 CCM03278.1 - 0.29 11.8 3.8 33 5.3 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCM03278.1 - 0.29 11.8 4.7 7.2 7.5 0.3 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat XPG_I PF00867.13 CCM03279.1 - 5.1e-18 64.9 0.0 1.2e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCM03279.1 - 0.00023 21.3 0.0 0.00052 20.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 CCM03279.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Nop14 PF04147.7 CCM03279.1 - 0.37 8.6 17.8 0.47 8.3 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 CCM03279.1 - 4.4 6.4 12.4 7.1 5.7 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein SWIRM PF04433.12 CCM03280.1 - 9.5e-37 125.0 0.0 1.5e-35 121.1 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 CCM03280.1 - 5.6e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 CCM03280.1 - 1.4e-08 34.1 2.9 2.4e-08 33.3 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CCM03280.1 - 2.1e-08 34.0 0.0 4.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chordopox_RPO7 PF05864.7 CCM03280.1 - 0.13 12.3 0.8 0.65 10.1 0.1 2.3 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) COesterase PF00135.23 CCM03281.1 - 4.4e-81 273.2 0.1 1.1e-80 271.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM03281.1 - 5.5e-09 35.9 0.1 1.9e-08 34.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM03281.1 - 3.9e-05 22.9 0.1 7.6e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCM03281.1 - 0.015 15.0 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIM PF00412.17 CCM03282.1 - 7.7e-31 105.9 26.6 6e-13 48.6 3.2 4.3 4 0 0 4 4 4 4 LIM domain PPR_2 PF13041.1 CCM03283.1 - 7e-17 61.1 0.2 9.3e-06 25.5 0.1 4.5 4 0 0 4 4 4 3 PPR repeat family PPR_3 PF13812.1 CCM03283.1 - 4.4e-12 45.2 7.2 0.057 13.7 0.0 5.9 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCM03283.1 - 6e-12 44.8 1.3 0.00014 21.2 0.1 4.0 4 0 0 4 4 4 3 PPR repeat PPR PF01535.15 CCM03283.1 - 3.3e-11 42.3 1.4 9e-05 22.1 0.2 5.1 5 0 0 5 5 5 3 PPR repeat SecD_SecF PF02355.11 CCM03284.1 - 0.053 12.7 0.4 0.071 12.2 0.2 1.3 1 1 0 1 1 1 0 Protein export membrane protein DUF350 PF03994.9 CCM03284.1 - 0.11 12.2 0.7 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Pkinase PF00069.20 CCM03286.1 - 3.8e-66 222.8 0.0 6.1e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03286.1 - 7.5e-32 110.4 0.0 1.3e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM03286.1 - 0.00032 20.4 0.0 0.00082 19.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Syntaxin-6_N PF09177.6 CCM03287.1 - 2.8e-23 82.1 4.2 4e-22 78.4 0.3 2.5 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 CCM03287.1 - 6.1e-12 45.0 3.1 6.1e-12 45.0 2.2 2.0 2 0 0 2 2 2 1 SNARE domain TMF_DNA_bd PF12329.3 CCM03287.1 - 0.0078 16.0 2.8 2.6 7.8 0.7 2.8 3 0 0 3 3 3 2 TATA element modulatory factor 1 DNA binding UBN2 PF14223.1 CCM03287.1 - 0.051 13.3 0.4 5.1 6.9 0.0 2.5 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF641 PF04859.7 CCM03287.1 - 0.1 12.3 3.9 0.31 10.7 0.2 2.5 2 2 0 2 2 2 0 Plant protein of unknown function (DUF641) HisKA_3 PF07730.8 CCM03287.1 - 0.14 12.5 0.2 0.14 12.5 0.1 2.9 3 1 0 3 3 3 0 Histidine kinase Laminin_II PF06009.7 CCM03287.1 - 0.14 11.8 0.9 15 5.3 0.1 2.4 2 0 0 2 2 2 0 Laminin Domain II FlaC_arch PF05377.6 CCM03287.1 - 0.18 11.7 3.1 3.8 7.4 0.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.6 CCM03287.1 - 0.18 11.1 1.1 0.5 9.7 0.1 2.1 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Cortex-I_coil PF09304.5 CCM03287.1 - 0.38 10.8 9.4 0.77 9.8 1.4 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil Laminin_I PF06008.9 CCM03287.1 - 0.6 9.3 8.3 0.57 9.4 0.2 2.6 2 1 0 2 2 2 0 Laminin Domain I TPR_MLP1_2 PF07926.7 CCM03287.1 - 1.2 8.9 4.9 8.6 6.1 1.5 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4618 PF15397.1 CCM03287.1 - 1.3 8.2 5.6 21 4.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Seryl_tRNA_N PF02403.17 CCM03287.1 - 2.9 7.9 6.0 1.6 8.7 0.3 2.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 CCM03287.1 - 6.9 7.1 8.5 0.24 11.8 0.4 2.4 3 1 1 4 4 3 0 N-terminal domain of unknown function (DUF4140) zf-C3HC4_3 PF13920.1 CCM03288.1 - 7.4e-11 41.5 5.2 2.9e-09 36.4 0.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCM03288.1 - 2.7e-06 27.2 5.0 5.5e-06 26.3 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCM03288.1 - 0.00013 21.7 4.1 0.0024 17.6 0.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCM03288.1 - 0.00018 21.0 2.1 0.00052 19.6 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM03288.1 - 0.0053 16.4 2.6 0.069 12.8 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 CCM03288.1 - 1.3 8.5 7.3 0.24 10.9 1.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF2360 PF10152.4 CCM03288.1 - 5.5 7.2 9.5 14 5.9 2.2 3.4 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Ribosomal_L18e PF00828.14 CCM03289.1 - 4.6e-37 127.2 0.2 6.4e-37 126.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RNA_pol_L_2 PF13656.1 CCM03290.1 - 6.7e-27 92.7 0.2 1.1e-26 92.0 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCM03290.1 - 2.1e-13 49.1 0.0 2.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 CCM03290.1 - 0.015 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal Zn_clus PF00172.13 CCM03291.1 - 0.43 10.5 9.8 0.68 9.8 2.3 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0220 PF05255.6 CCM03294.1 - 3.6e-52 175.9 0.0 4.6e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) adh_short PF00106.20 CCM03295.1 - 5.1e-28 98.0 0.9 6.3e-28 97.7 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM03295.1 - 2e-25 89.9 0.0 2.4e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM03295.1 - 9.9e-08 31.8 0.3 1.4e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCM03295.1 - 0.00039 20.1 0.0 0.0019 17.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 CCM03295.1 - 0.002 17.2 0.0 0.0046 16.0 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 CCM03295.1 - 0.0049 16.5 0.1 0.02 14.5 0.1 2.0 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 CCM03295.1 - 0.0092 15.4 0.2 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family OTCace PF00185.19 CCM03295.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NAD_binding_10 PF13460.1 CCM03295.1 - 0.026 14.5 0.2 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding MM_CoA_mutase PF01642.17 CCM03295.1 - 0.06 11.4 0.1 0.082 11.0 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase Aldo_ket_red PF00248.16 CCM03296.1 - 1.8e-44 151.6 0.0 2.6e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_FMN PF00724.15 CCM03296.1 - 6.4e-36 124.0 0.0 2e-34 119.1 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family LRR_4 PF12799.2 CCM03297.1 - 0.00016 21.1 1.4 3.8 7.2 0.0 4.4 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) PCMT PF01135.14 CCM03298.1 - 3.7e-64 216.1 0.0 4.5e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CCM03298.1 - 6.5e-07 29.9 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM03298.1 - 9.9e-07 28.6 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM03298.1 - 1.3e-06 28.4 0.2 7.4e-06 25.9 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM03298.1 - 2.8e-06 27.0 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCM03298.1 - 2.7e-05 23.8 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CCM03298.1 - 0.0051 17.6 0.1 0.044 14.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain EF-hand_1 PF00036.27 CCM03298.1 - 0.0078 15.4 0.0 0.028 13.7 0.0 2.0 2 0 0 2 2 2 1 EF hand Methyltransf_11 PF08241.7 CCM03298.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 CCM03298.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 CCM03298.1 - 0.046 12.8 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CCM03298.1 - 0.072 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 CCM03298.1 - 0.08 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PPTA PF01239.17 CCM03299.1 - 5.8e-44 145.6 14.8 6.1e-10 38.0 0.3 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 CCM03299.1 - 1.1 9.9 10.4 7.1 7.4 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat FoP_duplication PF13865.1 CCM03300.1 - 9.9e-07 29.1 0.5 1.2e-06 28.8 0.4 1.1 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.17 CCM03301.1 - 4.9e-10 38.8 0.0 7.9e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03301.1 - 1.2e-07 31.6 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.14 CCM03301.1 - 0.47 10.8 3.4 0.89 9.9 2.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.3 CCM03302.1 - 4.1e-32 112.0 24.9 1.3e-31 110.3 17.3 1.7 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 ATG16 PF08614.6 CCM03303.1 - 0.14 11.9 0.7 0.2 11.4 0.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SEEEED PF14797.1 CCM03303.1 - 1 9.5 15.8 1.1 9.4 10.5 1.4 1 1 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex DUF2217 PF10265.4 CCM03303.1 - 2.2 6.9 6.2 2.8 6.6 4.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PNRC PF15365.1 CCM03304.1 - 0.0014 18.5 2.4 0.0014 18.5 1.6 4.7 5 0 0 5 5 5 2 Proline-rich nuclear receptor coactivator PNRC PF15365.1 CCM03305.1 - 0.055 13.4 0.5 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator CBM_X PF06204.6 CCM03308.1 - 0.0035 16.7 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative carbohydrate binding domain DUF3317 PF11779.3 CCM03310.1 - 2.5e-08 33.2 4.2 2.5e-08 33.2 2.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3317) DUF3951 PF13131.1 CCM03310.1 - 1.9e-05 24.3 2.8 3.1e-05 23.6 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3951) Adeno_E3B PF03376.9 CCM03310.1 - 0.037 13.9 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3B protein Macoilin PF09726.4 CCM03312.1 - 0.11 10.8 18.0 0.22 9.7 12.5 1.5 1 0 0 1 1 1 0 Transmembrane protein COG2 PF06148.6 CCM03312.1 - 4.4 7.1 10.0 3.4 7.5 2.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_S7 PF00177.16 CCM03313.1 - 1.8e-40 137.9 0.7 2.2e-40 137.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Med12 PF09497.5 CCM03316.1 - 2.3e-25 88.3 0.1 6.2e-25 86.9 0.0 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 CCM03316.1 - 7e-05 21.4 0.0 0.0039 15.7 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain CPSase_sm_chain PF00988.17 CCM03318.1 - 2.6e-44 149.9 0.0 3.8e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CCM03318.1 - 7.8e-36 123.3 0.0 1.3e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCM03318.1 - 5.6e-08 32.5 0.1 6e-07 29.1 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 CCM03318.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family BSD PF03909.12 CCM03319.1 - 3.8e-06 26.5 0.2 9.8e-06 25.2 0.1 1.7 1 0 0 1 1 1 1 BSD domain DUF883 PF05957.8 CCM03319.1 - 0.017 15.5 0.2 1.1 9.7 0.0 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Nop14 PF04147.7 CCM03319.1 - 0.09 10.6 31.5 0.17 9.7 21.9 1.4 1 0 0 1 1 1 0 Nop14-like family Rhabdo_ncap PF00945.13 CCM03319.1 - 2.7 6.4 7.5 4.6 5.7 5.2 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SNF2_N PF00176.18 CCM03320.1 - 1.5e-51 174.9 0.0 4.8e-50 170.0 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.6 CCM03320.1 - 3.8e-17 62.1 0.0 8e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.13 CCM03320.1 - 1.4e-13 50.8 0.0 3.7e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_2 PF13923.1 CCM03320.1 - 5.1e-09 36.0 6.2 9.7e-09 35.1 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCM03320.1 - 9.6e-09 34.9 4.7 1.8e-08 34.0 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 CCM03320.1 - 1.9e-08 34.0 0.0 2.3e-07 30.5 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 CCM03320.1 - 2.6e-07 30.2 3.3 4.7e-07 29.3 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM03320.1 - 1e-06 28.3 3.5 2e-06 27.4 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCM03320.1 - 1.1e-06 28.1 5.8 2.2e-06 27.1 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM03320.1 - 2.9e-06 27.0 6.5 6.9e-06 25.8 4.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CCM03320.1 - 0.00027 20.6 2.3 0.00061 19.5 1.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CCM03320.1 - 0.00076 19.5 0.7 0.0019 18.2 0.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCM03320.1 - 0.0089 15.7 5.8 0.021 14.5 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 CCM03320.1 - 0.89 9.1 4.6 2.1 7.9 3.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 CCM03320.1 - 1.1 8.8 4.2 2.5 7.6 2.9 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Metallophos PF00149.23 CCM03321.1 - 0.0094 15.3 0.3 0.21 10.9 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DAGK_cat PF00781.19 CCM03322.1 - 3.9e-16 58.6 0.1 7.7e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain UDPGP PF01704.13 CCM03323.1 - 6.3e-179 594.8 1.0 7.4e-179 594.6 0.7 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase RCC1 PF00415.13 CCM03324.1 - 5.5e-15 55.3 1.4 0.0051 16.9 0.0 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCM03324.1 - 1.2e-10 40.7 18.1 0.00044 19.7 0.4 5.6 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 CCM03324.1 - 8.8e-06 25.3 1.4 2.1e-05 24.1 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM03324.1 - 0.00079 19.0 2.4 0.0014 18.1 1.7 1.5 1 0 0 1 1 1 1 F-box domain CHAT PF12770.2 CCM03325.1 - 1.6e-25 89.8 0.0 4.4e-12 45.7 0.0 2.3 1 1 1 2 2 2 2 CHAT domain TPR_12 PF13424.1 CCM03325.1 - 2.9e-13 49.5 0.0 1.6 8.6 0.0 9.1 4 1 6 10 10 10 3 Tetratricopeptide repeat DUF3745 PF12560.3 CCM03325.1 - 0.0036 16.9 0.1 1.2 8.8 0.0 4.6 7 0 0 7 7 7 1 Protein of unknown function (DUF3745) Med9 PF07544.8 CCM03325.1 - 0.017 14.8 0.1 25 4.6 0.0 4.8 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.7 CCM03325.1 - 0.51 10.7 1.9 2 8.8 0.0 2.9 3 0 0 3 3 3 0 SlyX UDPGP PF01704.13 CCM03327.1 - 4.1e-181 602.0 1.9 4.9e-181 601.8 1.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_S8e PF01201.17 CCM03328.1 - 1e-47 161.5 1.2 1.4e-47 161.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SET PF00856.23 CCM03329.1 - 1.8e-08 34.8 0.0 7.1e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 SET domain AT_hook PF02178.14 CCM03329.1 - 5.2 7.0 25.1 0.28 10.9 0.6 3.8 3 0 0 3 3 3 0 AT hook motif Cpn60_TCP1 PF00118.19 CCM03330.1 - 2.8e-148 494.5 0.1 3.9e-148 494.0 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PC_rep PF01851.17 CCM03331.1 - 0.013 15.7 15.3 2.4 8.5 0.0 5.3 6 0 0 6 6 6 0 Proteasome/cyclosome repeat Pkinase PF00069.20 CCM03332.1 - 7.2e-59 199.0 0.0 1.2e-58 198.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03332.1 - 2.8e-32 111.8 0.0 5.3e-32 110.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM03332.1 - 3.2e-06 26.3 0.0 5.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2397 PF09660.5 CCM03332.1 - 0.00077 18.1 1.1 0.0011 17.6 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) APH PF01636.18 CCM03332.1 - 0.14 11.8 2.0 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family SR-25 PF10500.4 CCM03333.1 - 0.015 14.7 3.9 0.021 14.3 2.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_L4 PF00573.17 CCM03334.1 - 2.3e-43 147.8 1.4 4.1e-43 147.0 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CCM03334.1 - 5.2e-28 96.7 3.3 5.2e-28 96.7 2.3 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain F-box-like PF12937.2 CCM03335.1 - 8.2e-05 22.2 2.1 0.00021 20.9 1.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM03335.1 - 0.058 13.0 3.0 0.07 12.8 0.5 2.3 2 0 0 2 2 2 0 F-box domain WD40 PF00400.27 CCM03336.1 - 2.9e-31 106.1 10.0 3.4e-07 29.8 0.1 7.3 6 1 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCM03336.1 - 0.0077 16.0 0.0 3.8 7.3 0.0 3.8 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.16 CCM03336.1 - 0.038 13.5 0.0 4.4 7.0 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat DUF3312 PF11768.3 CCM03336.1 - 0.1 10.7 0.0 0.88 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) F-box-like PF12937.2 CCM03337.1 - 3.4e-07 29.8 2.3 7.8e-07 28.7 1.6 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 CCM03337.1 - 0.6 10.0 3.8 3.6 7.6 0.2 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat Ten1_2 PF15490.1 CCM03338.1 - 7.5e-08 31.9 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit SKG6 PF08693.5 CCM03339.1 - 0.0029 16.8 0.2 0.0064 15.7 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 CCM03339.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.1 CCM03339.1 - 0.022 15.1 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 CCM03339.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4231 PF14015.1 CCM03339.1 - 0.16 11.9 0.1 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Spore_YhaL PF14147.1 CCM03339.1 - 3.1 7.3 0.0 3.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Sporulation protein YhaL DUF1768 PF08719.6 CCM03340.1 - 9.5e-22 77.4 0.0 1.4e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_3 PF08777.6 CCM03341.1 - 2e-06 27.6 0.0 1.8e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 RNA binding motif RRM_1 PF00076.17 CCM03341.1 - 0.00052 19.5 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03341.1 - 0.00058 19.7 0.0 2.2 8.3 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rubi_NSP_C PF12601.3 CCM03341.1 - 0.083 12.7 0.3 0.33 10.8 0.0 2.1 3 0 0 3 3 3 0 Rubivirus non-structural protein SKG6 PF08693.5 CCM03342.1 - 0.0022 17.2 0.2 0.0022 17.2 0.2 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Syndecan PF01034.15 CCM03342.1 - 0.1 12.2 0.3 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Dispanin PF04505.7 CCM03342.1 - 0.46 10.0 3.2 0.43 10.1 0.7 2.1 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Bacteriocin_IIc PF10439.4 CCM03342.1 - 1 9.5 4.7 2.7 8.1 3.3 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Beta-APP PF03494.8 CCM03342.1 - 2.3 7.7 4.0 4.3 6.8 2.8 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Mito_carr PF00153.22 CCM03343.1 - 5.1e-52 173.5 3.2 7.4e-17 60.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UQ_con PF00179.21 CCM03344.1 - 2e-20 72.6 0.0 3.6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 CCM03344.1 - 0.001 18.8 0.6 0.0036 17.1 0.4 2.0 1 0 0 1 1 1 1 UBA/TS-N domain IBR PF01485.16 CCM03344.1 - 0.0016 18.3 2.7 0.0035 17.1 1.9 1.5 1 0 0 1 1 1 1 IBR domain CENP-T PF15511.1 CCM03344.1 - 1.9 7.6 8.5 4.6 6.3 5.9 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Fungal_trans PF04082.13 CCM03345.1 - 6.6e-20 71.0 0.7 6.6e-20 71.0 0.5 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-CCHC PF00098.18 CCM03346.1 - 0.0013 18.5 37.8 0.0024 17.7 2.5 4.8 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.1 CCM03346.1 - 0.0054 16.4 18.7 0.099 12.3 1.5 4.6 3 1 1 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 CCM03346.1 - 0.02 14.5 1.8 0.02 14.5 1.3 4.7 3 1 2 5 5 5 0 Zinc knuckle ABC_tran PF00005.22 CCM03347.1 - 8.7e-16 58.4 0.0 2.8e-15 56.7 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCM03347.1 - 4.1e-10 40.1 0.8 0.00023 21.2 0.3 2.3 1 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CCM03347.1 - 0.00019 20.9 0.0 0.00044 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CCM03347.1 - 0.00044 19.4 0.0 0.16 10.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CCM03347.1 - 0.0006 19.2 0.1 0.0014 18.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CCM03347.1 - 0.0061 15.7 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SKG6 PF08693.5 CCM03347.1 - 0.0096 15.2 0.9 0.02 14.1 0.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PduV-EutP PF10662.4 CCM03347.1 - 0.026 13.9 0.1 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 CCM03347.1 - 0.062 13.6 0.1 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CCM03347.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 CCM03347.1 - 0.082 13.7 0.3 0.21 12.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CCM03347.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3609 PF12259.3 CCM03347.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) zf-C2H2 PF00096.21 CCM03348.1 - 0.00067 19.8 3.0 0.6 10.5 0.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type Alveol-reg_P311 PF11092.3 CCM03348.1 - 0.039 13.9 0.4 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Neuronal protein 3.1 (p311) zf-C2H2_4 PF13894.1 CCM03348.1 - 0.11 12.9 12.4 0.88 10.0 0.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Sporozoite_P67 PF05642.6 CCM03348.1 - 0.27 9.0 4.0 0.36 8.6 2.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-H2C2_2 PF13465.1 CCM03348.1 - 1.1 9.7 4.3 5.2 7.5 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 CCM03348.1 - 8.2 6.8 6.8 17 5.8 0.7 3.1 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Yae1_N PF09811.4 CCM03349.1 - 0.0038 16.7 5.6 0.0064 16.0 3.9 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Nucleoporin2 PF04096.9 CCM03350.1 - 2.4e-44 150.5 0.0 3.4e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CCM03350.1 - 0.027 14.7 91.8 6.5 7.0 43.4 5.3 1 1 0 2 2 2 0 Nucleoporin FG repeat region Nucleoporin_FG PF13634.1 CCM03351.1 - 1.4e-14 54.2 200.3 0.00011 22.4 26.7 6.2 2 2 2 4 4 4 3 Nucleoporin FG repeat region RNA_pol_Rpb2_6 PF00562.23 CCM03352.1 - 8e-111 370.4 0.0 1e-110 370.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCM03352.1 - 2e-31 108.4 0.0 3.2e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CCM03352.1 - 5.4e-26 90.1 0.0 1.1e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 CCM03352.1 - 1e-20 73.4 0.0 2.6e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 CCM03352.1 - 6.5e-18 64.7 0.0 2.4e-14 53.3 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 CCM03352.1 - 4.6e-13 48.9 0.0 1.4e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 CCM03352.1 - 0.01 15.8 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF4207 PF13904.1 CCM03354.1 - 2.6e-05 23.7 12.0 2.6e-05 23.7 8.3 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) zf-C2H2 PF00096.21 CCM03354.1 - 0.0083 16.4 15.0 0.21 12.0 1.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type Serinc PF03348.10 CCM03354.1 - 0.94 8.1 5.2 1.7 7.2 3.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) FimP PF09766.4 CCM03354.1 - 3.3 6.6 23.2 0.3 10.0 11.4 2.2 2 0 0 2 2 2 0 Fms-interacting protein AAA_23 PF13476.1 CCM03354.1 - 3.4 7.9 10.2 5.2 7.3 4.6 2.3 2 0 0 2 2 2 0 AAA domain zf-C2H2_4 PF13894.1 CCM03354.1 - 3.7 8.1 14.5 23 5.6 4.4 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger Methyltransf_23 PF13489.1 CCM03355.1 - 2.4e-14 53.3 0.0 3.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM03355.1 - 1.6e-09 38.0 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM03355.1 - 7.2e-09 35.4 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM03355.1 - 2e-08 34.5 0.0 4.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CCM03355.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 CCM03355.1 - 0.0052 16.1 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 CCM03355.1 - 0.0083 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM03355.1 - 0.011 16.3 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CCM03355.1 - 0.057 12.3 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family GidB PF02527.10 CCM03355.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.1 CCM03355.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CAP PF00188.21 CCM03355.1 - 0.11 12.9 0.0 0.74 10.3 0.0 2.0 2 0 0 2 2 2 0 Cysteine-rich secretory protein family FtsJ PF01728.14 CCM03355.1 - 0.12 12.2 0.0 0.27 11.2 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase tRNA_m1G_MT PF01746.16 CCM03356.1 - 5e-30 104.4 0.1 1.5e-23 83.3 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Ycf1 PF05758.7 CCM03356.1 - 0.093 10.4 3.4 0.11 10.2 2.3 1.2 1 0 0 1 1 1 0 Ycf1 DUF2058 PF09831.4 CCM03356.1 - 0.14 12.0 12.3 0.28 11.0 8.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DDRGK PF09756.4 CCM03356.1 - 0.17 11.2 15.4 0.29 10.5 10.7 1.3 1 0 0 1 1 1 0 DDRGK domain NARP1 PF12569.3 CCM03356.1 - 0.56 8.9 14.8 0.84 8.3 10.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 CCM03356.1 - 2.8 7.7 10.9 6 6.6 7.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MIP-T3 PF10243.4 CCM03356.1 - 5.3 5.3 24.1 9 4.6 16.7 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RNA_pol_Rpc4 PF05132.9 CCM03356.1 - 9.5 6.2 9.0 24 4.8 6.2 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 Abhydrolase_2 PF02230.11 CCM03357.1 - 2e-45 154.9 0.0 5e-45 153.5 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CCM03357.1 - 1.2e-07 31.5 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM03357.1 - 0.00013 21.8 0.0 0.0029 17.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 CCM03357.1 - 0.00052 19.5 0.0 0.00071 19.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 CCM03357.1 - 0.00075 18.9 0.0 0.00091 18.7 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CCM03357.1 - 0.0021 17.6 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 CCM03357.1 - 0.0065 16.2 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 CCM03357.1 - 0.012 15.2 0.1 0.35 10.3 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 CCM03357.1 - 0.023 13.9 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.20 CCM03357.1 - 0.033 13.7 0.0 0.085 12.4 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Peptidase_S9 PF00326.16 CCM03357.1 - 0.039 13.1 0.0 0.85 8.7 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.7 CCM03357.1 - 0.16 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) EVE PF01878.13 CCM03358.1 - 1.3e-40 138.6 0.1 2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 EVE domain SMK-1 PF04802.10 CCM03359.1 - 1.3e-60 204.2 5.6 1.3e-60 204.2 3.9 2.2 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RRM_1 PF00076.17 CCM03360.1 - 3.5e-11 42.5 0.2 8.4e-08 31.7 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM03360.1 - 0.011 15.5 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03360.1 - 0.066 13.1 0.0 0.75 9.8 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Band_7 PF01145.20 CCM03361.1 - 4.5e-27 95.0 2.2 8e-27 94.2 1.6 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family RGS PF00615.14 CCM03362.1 - 1.4e-05 25.2 0.0 0.00022 21.3 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain eIF2A PF08662.6 CCM03363.1 - 1.7e-42 145.3 0.6 1.1e-25 90.5 0.0 4.7 4 2 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CCM03363.1 - 2.6e-07 30.1 0.0 6.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CCM03363.1 - 1.2e-05 24.9 0.6 0.79 9.7 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat RRM_5 PF13893.1 CCM03363.1 - 0.002 17.9 0.0 0.0058 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03363.1 - 0.0041 17.0 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCM03364.1 - 2.9e-32 110.0 0.0 6.3e-16 57.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03364.1 - 2.5e-18 65.7 0.0 1.3e-09 37.9 0.0 4.2 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM03364.1 - 2e-11 43.5 0.0 7.1e-09 35.3 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCM03364.1 - 1.5e-05 24.7 0.1 4.7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCM03364.1 - 0.0033 17.1 0.0 0.0099 15.6 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif JmjC PF02373.17 CCM03365.1 - 5e-13 49.3 0.4 1.3e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CCM03365.1 - 6.6e-05 22.5 0.0 0.00024 20.7 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Prok-RING_2 PF14445.1 CCM03365.1 - 0.81 9.6 12.4 0.052 13.4 2.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 BAF1_ABF1 PF04684.8 CCM03365.1 - 3.3 6.4 9.0 7.3 5.3 6.3 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Response_reg PF00072.19 CCM03366.1 - 2.4e-24 85.4 0.1 1.1e-17 64.0 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Oxidored_nitro PF00148.14 CCM03366.1 - 0.0085 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase ATG2_CAD PF13329.1 CCM03366.1 - 0.19 11.2 0.3 0.62 9.6 0.1 1.9 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif DUF3546 PF12066.3 CCM03367.1 - 4.7e-14 52.3 0.3 4.7e-14 52.3 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 CCM03367.1 - 2.8e-11 44.0 1.8 2.8e-11 44.0 1.3 3.1 2 0 0 2 2 2 1 Arsenite-resistance protein 2 RRM_6 PF14259.1 CCM03367.1 - 1.2e-06 28.4 0.0 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCM03367.1 - 1.8e-05 24.3 0.0 0.53 9.9 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.1 CCM03367.1 - 5.7e-05 22.6 0.7 0.00021 20.8 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_5 PF13893.1 CCM03367.1 - 0.13 12.1 0.1 1.5 8.7 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Y_phosphatase3 PF13350.1 CCM03367.1 - 0.15 12.2 2.7 0.19 11.9 0.6 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family zf-C2H2_2 PF12756.2 CCM03367.1 - 0.38 10.8 2.3 3.6 7.7 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CCM03367.1 - 0.44 11.0 5.0 0.14 12.5 0.9 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type dUTPase PF00692.14 CCM03368.1 - 5.2e-40 135.8 0.0 6.5e-40 135.5 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF605 PF04652.11 CCM03369.1 - 0.76 9.1 15.2 0.97 8.7 10.5 1.1 1 0 0 1 1 1 0 Vta1 like ADH_N PF08240.7 CCM03370.1 - 8.7e-26 89.8 2.9 2.4e-25 88.4 2.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM03370.1 - 3.1e-18 65.5 0.1 5.7e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCM03370.1 - 0.014 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1686 PF07937.6 CCM03370.1 - 0.025 14.2 0.2 2.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) Vfa1 PF08432.5 CCM03371.1 - 4.8e-37 127.7 0.0 5.7e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 APC_CDC26 PF10471.4 CCM03371.1 - 0.045 14.4 2.3 0.045 14.4 1.6 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 XRCC4 PF06632.7 CCM03371.1 - 0.2 10.4 6.2 0.26 10.0 4.3 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Rtf2 PF04641.7 CCM03371.1 - 0.34 10.0 7.6 0.55 9.3 5.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.8 CCM03371.1 - 3.2 6.1 5.2 4.1 5.8 3.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nucleoside_tran PF01733.13 CCM03372.1 - 2.3e-40 138.6 11.0 2.3e-40 138.6 7.6 1.9 2 1 0 2 2 2 1 Nucleoside transporter GTP_EFTU PF00009.22 CCM03373.1 - 8.5e-46 155.7 0.0 1.4e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 CCM03373.1 - 1.7e-14 53.6 2.9 1.1e-13 51.1 0.5 2.5 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 CCM03373.1 - 5.1e-08 32.9 0.0 8.6e-07 29.0 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CCM03373.1 - 7.4e-06 25.9 0.0 6.8e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CCM03373.1 - 0.0025 17.9 0.1 0.005 16.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CCM03373.1 - 0.0048 17.3 0.0 0.1 13.0 0.0 2.6 1 1 0 1 1 1 1 Miro-like protein SSB PF00436.20 CCM03374.1 - 4.2e-17 61.9 0.0 5.5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DUF336 PF03928.9 CCM03375.1 - 0.0096 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Mg_trans_NIPA PF05653.9 CCM03376.1 - 1.6e-65 221.0 6.4 1.5e-61 207.9 1.9 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CCM03376.1 - 8e-06 26.0 0.2 8e-06 26.0 0.2 3.9 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CCM03376.1 - 5.2e-05 23.2 1.3 5.2e-05 23.2 0.9 3.7 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 CCM03376.1 - 0.027 13.3 5.2 0.019 13.8 0.8 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) WD40 PF00400.27 CCM03377.1 - 4.5e-14 51.7 1.1 8.5e-06 25.4 0.0 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat TFIID-31kDa PF02291.10 CCM03378.1 - 1.3e-31 109.0 0.0 2e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 CCM03378.1 - 0.00042 20.4 0.0 0.00084 19.4 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 CCM03378.1 - 0.00076 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 CCM03378.1 - 0.034 14.2 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF2415 PF10313.4 CCM03378.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) MBOAT PF03062.14 CCM03379.1 - 1.5e-42 145.8 3.7 3.6e-42 144.6 2.6 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.6 CCM03379.1 - 0.041 13.8 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) MARVEL PF01284.18 CCM03380.1 - 3.1e-07 30.3 20.1 4.7e-07 29.7 13.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain Oleosin PF01277.12 CCM03380.1 - 8.7 5.9 17.2 0.28 10.7 7.4 1.9 2 0 0 2 2 2 0 Oleosin Sugar_tr PF00083.19 CCM03381.1 - 2.2e-68 230.8 25.4 2.8e-51 174.5 4.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCM03381.1 - 2.2e-21 75.9 31.4 3.4e-20 72.0 15.6 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCM03381.1 - 3.3e-06 25.6 1.1 3.3e-06 25.6 0.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 CCM03383.1 - 8.2e-18 63.5 14.2 2.4e-07 30.3 0.3 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Carboxyl_trans PF01039.17 CCM03384.1 - 6.6e-145 483.2 0.1 8.2e-145 482.9 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CCM03384.1 - 0.0002 20.6 0.2 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Nop PF01798.13 CCM03385.1 - 1e-43 148.1 0.1 1.8e-43 147.4 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CCM03385.1 - 1.4e-36 125.6 3.2 2.6e-36 124.7 2.2 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 CCM03385.1 - 2.6e-19 68.7 0.0 1.4e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 NOSIC (NUC001) domain NifU_N PF01592.11 CCM03386.1 - 2.3e-51 172.9 0.0 3.2e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain DUF2838 PF10998.3 CCM03387.1 - 4.3e-38 129.6 11.7 8.6e-38 128.6 8.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) DUF2207 PF09972.4 CCM03387.1 - 0.026 13.1 1.8 0.35 9.3 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Atg14 PF10186.4 CCM03387.1 - 0.05 12.5 0.9 0.087 11.7 0.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Apolipoprotein PF01442.13 CCM03387.1 - 0.1 12.0 4.4 0.16 11.4 1.6 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain AAA_13 PF13166.1 CCM03387.1 - 0.24 9.8 1.5 0.35 9.2 1.0 1.1 1 0 0 1 1 1 0 AAA domain Curto_V3 PF07436.6 CCM03387.1 - 2.4 8.3 6.6 30 4.8 0.0 3.6 4 0 0 4 4 4 0 Curtovirus V3 protein A_deamin PF02137.13 CCM03388.1 - 5.1e-81 272.6 0.0 5.9e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain WD40 PF00400.27 CCM03390.1 - 3.2e-12 45.8 15.0 1.1e-07 31.4 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat p450 PF00067.17 CCM03391.1 - 3e-64 217.2 0.0 3.8e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 CCM03392.1 - 7.5e-24 84.5 0.3 9.6e-24 84.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM03392.1 - 2.2e-23 83.3 0.0 2.7e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM03392.1 - 1.7e-07 31.1 0.2 3.4e-07 30.1 0.0 1.4 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 CCM03392.1 - 0.0014 18.3 0.4 0.0023 17.5 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 CCM03392.1 - 0.032 14.6 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 CCM03392.1 - 0.038 13.7 0.2 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UDPG_MGDP_dh_N PF03721.9 CCM03392.1 - 0.048 13.0 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MTS PF05175.9 CCM03392.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF962 PF06127.6 CCM03393.1 - 6.4e-12 45.2 1.8 1.2e-11 44.2 1.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Longin PF13774.1 CCM03394.1 - 1.1e-30 105.0 0.1 1.5e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCM03394.1 - 5.9e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF4646 PF15496.1 CCM03395.1 - 1.2e-19 70.5 0.0 1e-18 67.5 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) YjgP_YjgQ PF03739.9 CCM03395.1 - 0.23 10.1 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family XRN_N PF03159.13 CCM03396.1 - 3.5e-106 353.9 0.6 5.4e-106 353.3 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 CCM03396.1 - 8.6e-05 22.2 1.5 0.00015 21.5 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCM03396.1 - 0.0029 17.3 1.2 0.0055 16.4 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle IF-2B PF01008.12 CCM03397.1 - 9.9e-85 283.9 0.1 1.2e-84 283.6 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family MTP18 PF10558.4 CCM03398.1 - 1.8e-57 193.4 0.7 2.1e-57 193.2 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) tRNA-synt_2 PF00152.15 CCM03399.1 - 9e-100 333.6 0.0 5.2e-52 176.6 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCM03399.1 - 3.9e-06 26.6 0.0 8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CCM03399.1 - 0.00052 19.6 0.0 0.029 13.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) IMD PF08397.6 CCM03400.1 - 3.8e-06 26.3 0.7 5.7e-06 25.8 0.5 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain Transposase_22 PF02994.9 CCM03400.1 - 0.027 12.9 0.8 0.051 12.0 0.6 1.4 1 0 0 1 1 1 0 L1 transposable element ARD PF03079.9 CCM03400.1 - 0.036 14.0 1.0 0.057 13.3 0.7 1.3 1 0 0 1 1 1 0 ARD/ARD' family WASH-7_C PF14746.1 CCM03400.1 - 0.06 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal ACPS PF01648.15 CCM03401.1 - 1.7e-13 50.4 0.0 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PfkB PF00294.19 CCM03402.1 - 2e-11 43.6 0.0 2.4e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CBFD_NFYB_HMF PF00808.18 CCM03403.1 - 8.5e-20 70.5 0.6 1.5e-19 69.7 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCM03403.1 - 0.0027 17.8 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Terpene_synth PF01397.16 CCM03403.1 - 0.024 14.0 1.4 0.028 13.8 1.0 1.2 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain MRP-S27 PF10037.4 CCM03403.1 - 0.052 12.4 3.6 0.055 12.3 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 TFIID-18kDa PF02269.11 CCM03403.1 - 0.063 13.1 0.3 0.13 12.1 0.2 1.7 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit 4HB_MCP_1 PF12729.2 CCM03403.1 - 0.51 9.6 5.0 0.54 9.5 2.9 1.5 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction LSM PF01423.17 CCM03404.1 - 3.1e-20 71.4 0.0 3.6e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCM03404.1 - 0.0041 17.0 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RRM_1 PF00076.17 CCM03405.1 - 4.2e-11 42.3 0.2 7.6e-09 35.0 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03405.1 - 3.9e-10 39.5 0.1 1.8e-09 37.4 0.1 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM03405.1 - 7.3e-06 25.7 0.0 3.4e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CCM03405.1 - 0.0083 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CCM03405.1 - 0.035 13.8 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 DEAD PF00270.24 CCM03406.1 - 5.7e-13 48.7 0.0 1.8e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM03406.1 - 0.00096 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.27 CCM03407.1 - 1.3e-57 189.7 33.0 2.3e-09 36.7 0.1 11.6 10 2 1 11 11 11 10 WD domain, G-beta repeat ACPS PF01648.15 CCM03408.1 - 3.5e-17 62.2 0.0 4e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GCV_T_C PF08669.6 CCM03409.1 - 0.019 15.0 0.0 0.045 13.7 0.0 1.7 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.16 CCM03409.1 - 0.06 12.7 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 Aminomethyltransferase folate-binding domain YppF PF14178.1 CCM03409.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 YppF-like protein GST_N_3 PF13417.1 CCM03410.1 - 6.8e-11 42.2 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCM03410.1 - 7.5e-09 35.4 0.0 1.2e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCM03410.1 - 8.7e-09 35.4 0.0 1.9e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM03410.1 - 6e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM03410.1 - 0.0039 17.0 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MT-A70 PF05063.9 CCM03411.1 - 3e-57 192.9 0.0 4.2e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 MT-A70 adh_short PF00106.20 CCM03412.1 - 1.7e-07 31.3 0.0 4.8e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM03412.1 - 0.00073 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 KR domain GMC_oxred_N PF00732.14 CCM03415.1 - 2.6e-62 210.6 0.0 3.3e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM03415.1 - 1.2e-31 109.9 0.0 1.9e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM03415.1 - 0.00012 21.1 0.1 0.013 14.3 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM03415.1 - 0.00037 19.5 0.2 0.00063 18.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCM03415.1 - 0.0073 15.1 1.0 0.59 8.9 0.2 2.5 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.12 CCM03415.1 - 0.0098 15.0 0.0 0.037 13.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 CCM03415.1 - 0.021 14.8 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CCM03415.1 - 0.086 11.4 0.1 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_4 PF07993.7 CCM03416.1 - 1.4e-29 102.7 0.0 2.3e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 CCM03416.1 - 9.3e-29 100.0 0.0 4.9e-27 94.3 0.0 2.5 3 0 0 3 3 3 1 AMP-binding enzyme Epimerase PF01370.16 CCM03416.1 - 1e-09 38.2 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CCM03416.1 - 0.0002 21.3 0.9 0.0015 18.4 0.2 2.4 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 CCM03416.1 - 0.0016 18.6 0.2 0.012 15.9 0.1 2.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 CCM03416.1 - 0.0024 17.5 0.1 0.0024 17.5 0.1 2.3 3 0 0 3 3 3 1 KR domain NAD_binding_10 PF13460.1 CCM03416.1 - 0.0028 17.6 0.0 0.015 15.3 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 CCM03416.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F-box-like PF12937.2 CCM03420.1 - 0.00029 20.4 0.2 0.001 18.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.8 CCM03420.1 - 0.91 10.1 0.1 0.91 10.1 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat DUF282 PF03380.9 CCM03422.1 - 0.034 13.8 0.8 10 5.9 0.0 3.3 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF282 DUF282 PF03380.9 CCM03423.1 - 0.11 12.3 1.6 0.78 9.5 0.2 2.6 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF282 RTA1 PF04479.8 CCM03424.1 - 3.9e-43 147.5 1.3 5.7e-43 147.0 0.9 1.1 1 0 0 1 1 1 1 RTA1 like protein p450 PF00067.17 CCM03425.1 - 6.8e-48 163.3 0.0 9.2e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Imm47 PF15586.1 CCM03425.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 47 Methyltransf_25 PF13649.1 CCM03426.1 - 1.2e-08 35.2 0.1 5.9e-08 32.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM03426.1 - 0.0039 16.7 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain SQS_PSY PF00494.14 CCM03427.1 - 3.3e-20 72.4 0.0 4.6e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase TGS PF02824.16 CCM03427.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 TGS domain polyprenyl_synt PF00348.12 CCM03428.1 - 4.7e-54 182.9 0.0 6e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 CCM03429.1 - 1.1e-43 149.4 0.0 1.7e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 CCM03430.1 - 0.035 13.3 1.1 0.049 12.8 0.8 1.3 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF3681 PF12442.3 CCM03430.1 - 0.63 10.2 4.9 1.7 8.8 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) SQS_PSY PF00494.14 CCM03431.1 - 1.9e-33 115.8 0.0 2.8e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase YxiJ PF14176.1 CCM03431.1 - 0.06 13.4 0.4 1.6 8.8 0.0 3.1 3 1 1 4 4 4 0 YxiJ-like protein p450 PF00067.17 CCM03432.1 - 2.5e-22 79.0 0.0 1.6e-11 43.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SQS_PSY PF00494.14 CCM03433.1 - 2.1e-21 76.3 0.0 3.1e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Sod_Fe_C PF02777.13 CCM03434.1 - 5.1e-37 125.9 0.1 8e-37 125.3 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCM03434.1 - 4.9e-33 113.2 3.0 4.9e-33 113.2 2.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain TisB_toxin PF13939.1 CCM03436.1 - 0.054 13.2 0.2 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system UbiA PF01040.13 CCM03439.1 - 8.2e-07 28.4 14.4 1.5e-05 24.3 9.7 2.1 1 1 0 1 1 1 1 UbiA prenyltransferase family GMC_oxred_C PF05199.8 CCM03440.1 - 3.3e-35 121.5 0.1 5.1e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CCM03440.1 - 5.1e-29 101.3 0.0 6.6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CCM03441.1 - 1.2e-66 224.8 0.4 2e-66 224.1 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM03441.1 - 2.3e-38 131.7 0.0 4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCM03441.1 - 3.9e-05 22.6 2.1 0.045 12.6 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 CCM03441.1 - 0.00077 18.4 3.1 0.0016 17.4 0.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM03441.1 - 0.00082 18.3 0.1 0.0015 17.4 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CCM03441.1 - 0.0016 18.4 0.1 0.0055 16.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCM03441.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCM03441.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pil1 PF13805.1 CCM03443.1 - 1.9e-12 46.9 0.1 3.7e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 IFT57 PF10498.4 CCM03443.1 - 0.012 14.4 0.3 0.018 13.8 0.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 MAD PF05557.8 CCM03443.1 - 0.046 11.8 0.5 0.061 11.4 0.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF1421 PF07223.6 CCM03443.1 - 0.75 9.5 17.9 0.97 9.1 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) GMC_oxred_N PF00732.14 CCM03445.1 - 1.4e-17 63.8 0.0 2.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM03445.1 - 0.00036 20.8 0.0 0.00059 20.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase VHS PF00790.14 CCM03446.1 - 2.7e-37 127.5 0.0 6.1e-37 126.3 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CCM03446.1 - 2.5e-16 59.4 0.0 5.6e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 GAT domain DUF3216 PF11505.3 CCM03446.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) p450 PF00067.17 CCM03447.1 - 1.5e-77 261.0 0.0 2.7e-64 217.4 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 vATP-synt_E PF01991.13 CCM03448.1 - 7.7e-55 185.2 13.3 8.9e-55 185.0 9.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phospholamban PF04272.9 CCM03448.1 - 0.19 11.1 1.5 0.3 10.5 0.3 1.9 2 0 0 2 2 2 0 Phospholamban Vfa1 PF08432.5 CCM03448.1 - 7.8 6.4 10.6 1.2 9.0 4.6 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Glyco_hyd_65N_2 PF14498.1 CCM03449.1 - 8.6e-33 113.9 2.2 1.2e-29 103.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 65, N-terminal domain Acetyltransf_CG PF14542.1 CCM03450.1 - 0.011 15.6 0.0 0.15 11.9 0.0 2.4 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.19 CCM03450.1 - 0.019 14.9 0.2 0.078 13.0 0.0 2.0 1 1 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CCM03450.1 - 0.068 13.0 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Bestrophin PF01062.16 CCM03451.1 - 9.1e-44 149.5 5.9 3.6e-26 91.7 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel F-box-like PF12937.2 CCM03452.1 - 1.4e-05 24.6 0.7 1.4e-05 24.6 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM03452.1 - 0.00013 21.5 0.6 0.00013 21.5 0.4 2.4 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 CCM03452.1 - 0.021 14.4 4.1 12 5.6 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) bZIP_Maf PF03131.12 CCM03453.1 - 0.024 14.9 1.3 0.056 13.7 0.9 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor ATG27 PF09451.5 CCM03455.1 - 5.2e-18 65.2 0.0 3e-17 62.7 0.0 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 CCM03455.1 - 0.00023 20.9 0.3 0.0065 16.2 0.0 2.1 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat APG12 PF04110.8 CCM03456.1 - 7.2e-31 106.2 0.0 9.3e-31 105.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 CCM03456.1 - 0.0017 18.3 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Methyltransf_3 PF01596.12 CCM03459.1 - 2.9e-46 157.1 0.0 3.3e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 CCM03459.1 - 6.9e-17 62.2 0.0 1.4e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM03459.1 - 2e-11 43.7 0.0 7.2e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM03459.1 - 6.2e-10 39.6 0.0 9.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM03459.1 - 7.9e-08 32.3 0.0 2.8e-07 30.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CCM03459.1 - 8.3e-06 25.4 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 CCM03459.1 - 0.0029 17.0 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 CCM03459.1 - 0.0045 17.4 0.0 0.048 14.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCM03459.1 - 0.048 12.7 0.0 0.1 11.6 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 CCM03459.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ADH_N PF08240.7 CCM03460.1 - 1e-17 63.8 1.0 1.7e-17 63.1 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM03460.1 - 8e-16 57.7 0.1 1.7e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase APG12 PF04110.8 CCM03461.1 - 6e-30 103.2 0.0 7e-30 103.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 CCM03461.1 - 0.0026 17.7 0.0 0.0028 17.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like GST_N_3 PF13417.1 CCM03462.1 - 2.1e-07 31.0 0.1 5.5e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM03462.1 - 0.00038 20.4 0.1 0.00069 19.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Transaldolase PF00923.14 CCM03463.1 - 9.5e-96 320.2 0.0 1.1e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Peptidase_M14 PF00246.19 CCM03464.1 - 5e-59 200.1 0.1 6.7e-59 199.7 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Beta-APP PF03494.8 CCM03465.1 - 0.048 13.1 0.2 0.079 12.4 0.1 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF2422 PF10337.4 CCM03466.1 - 2.2e-80 270.7 0.2 6e-80 269.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CCM03466.1 - 1.6e-31 109.7 0.0 3.6e-28 98.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 CCM03466.1 - 1.5e-07 31.3 18.0 1.5e-07 31.3 12.4 4.4 4 0 0 4 4 4 1 Fusaric acid resistance protein-like PTR2 PF00854.16 CCM03467.1 - 1.6e-45 155.5 9.5 3.4e-44 151.1 6.6 2.1 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 CCM03467.1 - 2.8e-09 36.1 23.4 6.5e-09 34.9 16.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3529 PF12046.3 CCM03467.1 - 0.14 11.1 0.1 0.26 10.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) DUF872 PF05915.7 CCM03467.1 - 0.63 9.9 3.8 15 5.4 1.3 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) His_Phos_2 PF00328.17 CCM03468.1 - 1.4e-31 110.0 0.0 2.4e-31 109.3 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rad17 PF03215.10 CCM03469.1 - 6.1e-55 186.8 0.0 5.7e-53 180.3 0.0 2.8 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CCM03469.1 - 7.6e-05 23.5 0.0 0.00046 21.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCM03469.1 - 0.0002 21.5 0.0 0.0006 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM03469.1 - 0.00031 20.7 0.2 0.0013 18.7 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CCM03469.1 - 0.00044 19.9 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 CCM03469.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCM03469.1 - 0.02 15.1 0.0 0.056 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CCM03469.1 - 0.032 14.1 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 CCM03469.1 - 0.035 13.6 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.9 CCM03469.1 - 0.093 10.4 0.0 0.13 9.9 0.0 1.1 1 0 0 1 1 1 0 Helicase 3-HAO PF06052.7 CCM03470.1 - 8.5e-58 194.0 0.0 9.6e-58 193.8 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 CCM03470.1 - 1.7e-07 30.6 0.1 2.5e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CCM03470.1 - 0.0041 16.5 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 CCM03470.1 - 0.0074 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain zf-tcix PF14952.1 CCM03470.1 - 0.019 14.2 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF4059 PF13268.1 CCM03473.1 - 4.8 7.4 10.0 0.33 11.1 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) DUF4482 PF14818.1 CCM03475.1 - 0.044 14.4 0.4 0.17 12.5 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) Pkinase PF00069.20 CCM03476.1 - 3.9e-11 42.5 0.0 3e-10 39.7 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03476.1 - 0.00011 21.4 0.0 0.00047 19.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Corona_NS1 PF06145.6 CCM03476.1 - 0.026 13.8 0.9 0.078 12.2 0.6 1.8 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 ThiF PF00899.16 CCM03477.1 - 1e-40 138.7 0.0 1.3e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.4 CCM03477.1 - 5.5e-20 70.4 1.9 8.9e-20 69.8 1.3 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 CCM03477.1 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.5 1 1 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCM03477.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 CCM03477.1 - 0.042 13.6 0.1 0.064 13.0 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UBACT PF02134.16 CCM03478.1 - 3.5e-28 96.9 0.2 5.7e-28 96.2 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 CCM03478.1 - 1.3e-06 28.3 0.0 3.4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DAP_C PF07932.7 CCM03479.1 - 0.13 12.3 0.0 5.1 7.3 0.0 2.3 2 0 0 2 2 2 0 D-aminopeptidase, domain C Spc24 PF08286.6 CCM03480.1 - 0.19 11.4 1.4 0.22 11.2 0.1 1.9 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4138 PF13595.1 CCM03481.1 - 0.029 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) PDR_CDR PF06422.7 CCM03481.1 - 1.4 8.6 9.6 0.62 9.7 0.1 3.2 3 1 0 3 3 3 0 CDR ABC transporter PTCB-BRCT PF12738.2 CCM03482.1 - 2e-24 85.1 5.7 1.7e-16 59.7 0.6 3.6 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.21 CCM03482.1 - 4e-17 62.1 0.0 2.1e-08 34.2 0.0 3.9 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain RabGAP-TBC PF00566.13 CCM03483.1 - 1e-31 110.0 0.0 1.6e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.12 CCM03483.1 - 0.011 15.1 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.23 CCM03483.1 - 0.27 10.6 0.2 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 SH3 domain Ribosomal_S17 PF00366.15 CCM03484.1 - 2.3e-14 53.1 0.1 3.2e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Prefoldin_2 PF01920.15 CCM03485.1 - 1.9e-24 85.4 10.0 2.6e-24 85.0 6.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 CCM03485.1 - 0.0054 16.3 10.4 0.2 11.3 1.9 2.2 2 0 0 2 2 2 2 Prefoldin subunit NPV_P10 PF05531.7 CCM03485.1 - 0.015 15.5 8.1 0.29 11.4 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.8 CCM03485.1 - 0.019 15.7 4.1 2.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain IFT57 PF10498.4 CCM03485.1 - 0.029 13.1 8.1 0.034 12.8 5.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Prefoldin_3 PF13758.1 CCM03485.1 - 0.04 13.7 4.9 0.36 10.6 3.2 2.2 1 1 0 1 1 1 0 Prefoldin subunit DUF4201 PF13870.1 CCM03485.1 - 0.064 12.7 5.9 0.93 8.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ADSL_C PF10397.4 CCM03485.1 - 0.11 12.5 0.4 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus DUF607 PF04678.8 CCM03485.1 - 0.11 12.3 2.6 0.22 11.4 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF607 Nsp1_C PF05064.8 CCM03485.1 - 0.14 11.8 10.0 0.77 9.4 0.8 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region TBPIP PF07106.8 CCM03485.1 - 0.14 11.6 12.5 0.77 9.2 1.2 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) End3 PF12761.2 CCM03485.1 - 0.15 11.6 8.3 0.24 11.0 5.8 1.3 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 CCDC-167 PF15188.1 CCM03485.1 - 0.15 11.9 3.5 1.3 8.9 0.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Tropomyosin_1 PF12718.2 CCM03485.1 - 0.17 11.7 9.7 0.5 10.2 0.7 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF972 PF06156.8 CCM03485.1 - 0.17 12.2 9.9 0.41 11.0 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 CCM03485.1 - 0.2 11.7 8.8 1.8 8.5 4.0 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 CCM03485.1 - 0.21 10.5 4.9 0.24 10.3 3.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 CCM03485.1 - 0.22 11.3 9.7 0.79 9.5 0.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 CCM03485.1 - 0.24 11.1 8.1 0.36 10.5 0.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein LLC1 PF14945.1 CCM03485.1 - 0.28 11.5 1.5 0.72 10.1 0.2 1.9 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein NEP PF10167.4 CCM03485.1 - 0.28 10.8 2.9 0.22 11.2 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein DUF641 PF04859.7 CCM03485.1 - 0.32 10.7 7.9 0.58 9.9 2.0 2.1 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) MscS_porin PF12795.2 CCM03485.1 - 0.34 10.2 12.4 1.1 8.5 2.3 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TcdA_TcdB PF12919.2 CCM03485.1 - 0.43 8.9 3.8 0.49 8.8 2.7 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Cluap1 PF10234.4 CCM03485.1 - 0.46 9.6 9.6 0.95 8.6 6.6 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 APG6 PF04111.7 CCM03485.1 - 0.7 8.8 10.1 3.4 6.6 7.0 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 CCM03485.1 - 0.88 8.6 3.2 1.5 7.9 2.3 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF4164 PF13747.1 CCM03485.1 - 0.94 9.6 5.9 1.6 8.9 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF720 PF05302.6 CCM03485.1 - 1 9.1 7.7 0.24 11.1 1.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF720) IncA PF04156.9 CCM03485.1 - 1.1 8.8 12.5 14 5.2 8.7 1.9 1 1 0 1 1 1 0 IncA protein zf-CpG_bind_C PF12269.3 CCM03485.1 - 1.2 8.5 6.0 0.33 10.3 1.0 1.9 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain DMPK_coil PF08826.5 CCM03485.1 - 1.6 8.7 13.2 0.77 9.7 2.5 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Mnd1 PF03962.10 CCM03485.1 - 1.9 8.1 8.1 8.1 6.0 5.6 1.8 1 1 0 1 1 1 0 Mnd1 family COG2 PF06148.6 CCM03485.1 - 2.4 8.0 9.7 7.1 6.5 0.7 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 CCM03485.1 - 3.3 7.5 7.7 5.8 6.7 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CCM03485.1 - 3.6 7.5 6.7 18 5.3 0.1 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) PNPase PF03726.9 CCM03485.1 - 3.7 7.8 6.5 1.7 8.9 1.3 2.0 1 1 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Cauli_AT PF03233.8 CCM03485.1 - 3.7 7.2 7.3 9.8 5.8 0.9 2.0 1 1 1 2 2 2 0 Aphid transmission protein Fib_alpha PF08702.5 CCM03485.1 - 3.8 7.6 7.6 5.9 7.0 0.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CDC37_N PF03234.9 CCM03485.1 - 3.9 7.7 8.1 8 6.7 5.6 1.6 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding YgaB PF14182.1 CCM03485.1 - 5.1 7.4 8.4 0.99 9.6 1.7 2.3 2 1 0 2 2 2 0 YgaB-like protein FlxA PF14282.1 CCM03485.1 - 8 6.4 11.0 3.1 7.7 1.9 2.3 2 0 0 2 2 2 0 FlxA-like protein V-SNARE PF05008.10 CCM03486.1 - 2.6e-21 75.5 12.4 5.1e-21 74.6 3.9 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 CCM03486.1 - 1.7e-14 53.6 7.8 1.7e-14 53.6 5.4 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CCM03486.1 - 0.0014 18.3 0.3 0.0014 18.3 0.2 1.9 2 1 0 2 2 2 1 Sec20 DUF2275 PF10039.4 CCM03486.1 - 0.019 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Prominin PF05478.6 CCM03486.1 - 0.028 11.9 2.7 0.11 10.0 1.8 1.8 1 1 0 1 1 1 0 Prominin Fusion_gly PF00523.13 CCM03486.1 - 0.074 11.1 0.2 0.14 10.1 0.2 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 YqjK PF13997.1 CCM03486.1 - 0.14 12.3 2.4 0.41 10.8 1.6 1.9 1 0 0 1 1 1 0 YqjK-like protein DUF2564 PF10819.3 CCM03486.1 - 0.28 11.3 4.9 1.4 9.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) DUF4337 PF14235.1 CCM03486.1 - 0.31 10.8 4.6 1.6 8.5 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF1366 PF07104.6 CCM03486.1 - 0.4 10.2 0.1 0.4 10.2 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1366) Sec8_exocyst PF04048.9 CCM03486.1 - 0.73 9.4 4.2 0.8 9.3 0.1 2.6 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Flagellin_N PF00669.15 CCM03486.1 - 1.6 8.5 10.6 0.29 10.9 1.6 2.6 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF2937 PF11157.3 CCM03486.1 - 6.9 5.9 11.2 0.85 8.9 0.4 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF2937) Exonuc_VII_L PF02601.10 CCM03486.1 - 7.8 5.5 9.7 3.1 6.9 0.9 2.0 1 1 0 2 2 2 0 Exonuclease VII, large subunit Mpv17_PMP22 PF04117.7 CCM03487.1 - 2.4e-25 87.9 0.8 5.4e-25 86.8 0.6 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2421 PF10334.4 CCM03488.1 - 4.8e-56 189.9 0.1 7.4e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CCM03488.1 - 8.5e-50 169.8 2.4 8.5e-50 169.8 1.7 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CCM03488.1 - 8.6e-08 32.1 17.1 8.6e-08 32.1 11.8 3.2 2 1 0 2 2 2 1 Fusaric acid resistance protein-like UNC-79 PF14776.1 CCM03488.1 - 0.049 12.0 0.2 0.074 11.4 0.1 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 LSM PF01423.17 CCM03489.1 - 1.8e-13 49.7 0.1 2.1e-13 49.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCM03489.1 - 7.3e-06 25.8 0.1 9e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Zn_clus PF00172.13 CCM03490.1 - 1.7e-09 37.3 9.5 2.7e-09 36.8 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.16 CCM03491.1 - 7.1e-149 496.5 0.1 8.6e-149 496.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family RIO1 PF01163.17 CCM03492.1 - 6.3e-50 169.1 2.9 1.5e-35 122.3 0.0 2.7 3 0 0 3 3 3 2 RIO1 family DUF4662 PF15578.1 CCM03492.1 - 0.61 9.6 6.7 1 8.8 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) RAP1 PF07218.6 CCM03494.1 - 3.4 5.6 7.1 4.4 5.2 4.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Corona_nucleoca PF00937.13 CCM03494.1 - 8.7 5.1 9.3 15 4.3 6.4 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AAA_23 PF13476.1 CCM03496.1 - 6.7e-15 55.9 30.9 6.7e-15 55.9 21.4 7.8 1 1 3 5 5 2 1 AAA domain AAA_21 PF13304.1 CCM03496.1 - 7.8e-14 52.3 5.9 6.9e-08 32.8 0.3 3.6 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 CCM03496.1 - 5.1e-11 42.3 0.0 2.1e-10 40.3 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 CCM03496.1 - 1.6e-09 36.8 122.4 2.4e-05 23.0 0.0 7.6 3 2 4 7 7 7 4 AAA domain SMC_N PF02463.14 CCM03496.1 - 1.8e-09 37.1 0.0 1.8e-09 37.1 0.0 2.9 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CCM03496.1 - 0.00021 20.4 15.6 0.00021 20.4 10.8 4.9 1 1 2 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 CCM03496.1 - 0.00063 19.2 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4094 PF13334.1 CCM03496.1 - 0.0045 17.3 4.1 0.0045 17.3 2.8 7.1 7 2 0 7 7 6 2 Domain of unknown function (DUF4094) Pox_A_type_inc PF04508.7 CCM03496.1 - 0.0054 16.4 0.5 0.0054 16.4 0.3 8.5 9 0 0 9 9 8 1 Viral A-type inclusion protein repeat TMF_DNA_bd PF12329.3 CCM03496.1 - 0.0073 16.0 1.0 0.0073 16.0 0.7 14.1 6 3 8 14 14 14 2 TATA element modulatory factor 1 DNA binding DUF2001 PF09393.5 CCM03496.1 - 0.009 15.7 0.0 0.009 15.7 0.0 6.2 6 1 0 6 6 6 1 Protein of unknown function (DUF2001) AAA_19 PF13245.1 CCM03496.1 - 0.045 13.4 0.0 0.21 11.3 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 CCM03496.1 - 2.7 7.0 38.8 0.017 14.3 3.6 6.7 3 2 6 9 9 9 0 Reovirus sigma C capsid protein DUF2205 PF10224.4 CCM03497.1 - 3e-12 45.9 0.4 3.8e-12 45.6 0.3 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 CCM03497.1 - 0.0015 18.8 0.8 0.0017 18.6 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) INT_SG_DDX_CT_C PF15300.1 CCM03497.1 - 0.037 13.4 0.1 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus RPW8 PF05659.6 CCM03497.1 - 0.038 13.5 0.2 0.044 13.3 0.2 1.0 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DAP_B PF07930.7 CCM03497.1 - 0.071 12.8 0.1 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 D-aminopeptidase, domain B bZIP_1 PF00170.16 CCM03497.1 - 0.077 12.9 0.3 0.18 11.7 0.1 1.7 1 1 1 2 2 2 0 bZIP transcription factor Sas10_Utp3 PF04000.10 CCM03497.1 - 0.098 12.8 0.1 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Proteasom_Rpn13 PF04683.8 CCM03498.1 - 4.6e-28 97.1 0.0 5.9e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Arf PF00025.16 CCM03500.1 - 3.3e-35 120.8 0.0 3.4e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCM03500.1 - 4.1e-18 65.3 0.0 4.9e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM03500.1 - 1.4e-10 41.6 0.0 2.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CCM03500.1 - 2e-08 33.7 0.0 2.3e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCM03500.1 - 2.9e-07 29.8 0.0 3.7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CCM03500.1 - 8.1e-06 24.7 0.8 1.2e-05 24.2 0.1 1.7 2 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 CCM03500.1 - 6.6e-05 22.8 0.0 8.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCM03500.1 - 0.0026 17.2 0.0 0.011 15.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCM03500.1 - 0.021 14.6 0.6 0.38 10.5 0.6 2.0 1 1 1 2 2 2 0 Dynamin family Pet127 PF08634.5 CCM03501.1 - 1.6e-93 312.8 0.0 2.2e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Usp PF00582.21 CCM03502.1 - 1.1e-09 38.5 0.4 4.5e-08 33.3 0.0 2.8 2 0 0 2 2 2 1 Universal stress protein family Pkinase PF00069.20 CCM03504.1 - 1.4e-64 217.7 0.0 1.7e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03504.1 - 2.7e-37 128.2 0.0 1.1e-35 122.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM03504.1 - 3.9e-05 22.7 0.0 0.00012 21.1 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CCM03504.1 - 0.044 12.6 0.4 0.11 11.2 0.0 1.8 3 0 0 3 3 3 0 Seadornavirus VP7 APH PF01636.18 CCM03504.1 - 0.091 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2235 PF09994.4 CCM03505.1 - 6.4e-75 252.0 0.0 9.3e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 CCM03505.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 CCM03506.1 - 6.8e-52 176.1 0.0 1.2e-51 175.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Cullin PF00888.17 CCM03506.1 - 2.3e-40 138.7 0.0 4.6e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 Cullin family Pkinase_Tyr PF07714.12 CCM03506.1 - 1.6e-33 115.9 0.0 2.6e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APC2 PF08672.6 CCM03506.1 - 2.7e-09 37.1 0.1 9.4e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Kinase-like PF14531.1 CCM03506.1 - 8.5e-05 21.6 0.0 0.00047 19.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCM03506.1 - 0.0091 15.7 0.2 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_S9 PF00326.16 CCM03507.1 - 1.9e-13 50.1 0.0 8.3e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CCM03507.1 - 4e-09 36.3 0.0 0.00019 21.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM03507.1 - 1.7e-07 31.1 0.6 1.5e-06 28.0 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CCM03507.1 - 1.1e-05 24.8 0.0 0.0091 15.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.13 CCM03507.1 - 0.0001 21.8 0.0 0.00057 19.3 0.0 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 CCM03507.1 - 0.00012 21.9 1.1 0.00025 20.9 0.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCM03507.1 - 0.029 13.8 0.1 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CCM03507.1 - 0.03 14.0 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 CCM03507.1 - 0.13 10.7 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) SIR2 PF02146.12 CCM03508.1 - 3.7e-59 199.4 0.0 5e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Peptidase_S28 PF05577.7 CCM03509.1 - 7.4e-56 189.5 0.0 3.4e-55 187.3 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 F-box-like PF12937.2 CCM03510.1 - 2.5e-06 27.0 0.5 2.5e-06 27.0 0.4 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 CCM03510.1 - 9.1 6.0 11.2 0.86 9.3 1.1 3.9 3 1 0 3 3 3 0 F-box domain peroxidase PF00141.18 CCM03511.1 - 4.8e-21 75.3 0.0 6.7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase YjeF_N PF03853.10 CCM03512.1 - 1.3e-36 125.7 0.0 2.3e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus EBP PF05241.7 CCM03513.1 - 2.6e-64 215.8 10.5 3.3e-64 215.5 7.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein 7tm_1 PF00001.16 CCM03513.1 - 0.01 15.0 0.2 0.019 14.0 0.1 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Amidohydro_1 PF01979.15 CCM03514.1 - 6.4e-26 91.7 0.0 8.2e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CCM03514.1 - 0.0018 17.6 0.3 0.016 14.4 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 CCM03514.1 - 0.0023 18.0 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 CCM03514.1 - 0.078 12.8 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Amidohydrolase BTB PF00651.26 CCM03515.1 - 1.7e-07 31.1 0.0 3.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Mon1 PF03164.9 CCM03516.1 - 1.7e-101 339.8 0.0 6e-64 216.1 0.1 2.1 2 0 0 2 2 2 2 Trafficking protein Mon1 SEEK1 PF15357.1 CCM03516.1 - 0.025 14.4 0.7 0.054 13.3 0.1 1.8 2 0 0 2 2 2 0 Psoriasis susceptibility 1 candidate 1 IGR PF09597.5 CCM03517.1 - 1.2e-14 53.9 0.1 1.7e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 IGR protein motif FHA PF00498.21 CCM03518.1 - 7.9e-18 64.3 0.0 1.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain ErmC PF06308.6 CCM03518.1 - 0.043 13.8 0.3 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 23S rRNA methylase leader peptide (ErmC) MIP-T3 PF10243.4 CCM03518.1 - 0.11 10.9 14.1 0.12 10.8 9.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Lipase_3 PF01764.20 CCM03519.1 - 2.1e-18 66.2 0.0 3.1e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CCM03519.1 - 0.0026 17.6 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM03519.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 CCM03519.1 - 0.075 12.3 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 CCM03519.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 CCM03519.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Zn_clus PF00172.13 CCM03520.1 - 8.5e-08 31.9 10.6 8.5e-08 31.9 7.4 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_5 PF13854.1 CCM03521.1 - 2.6e-16 59.1 0.4 2.4e-05 24.1 0.1 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 CCM03521.1 - 2.3e-15 56.0 3.8 0.0005 19.7 0.0 4.9 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CCM03521.1 - 2.2e-14 53.1 4.6 3.2e-05 23.9 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 CCM03521.1 - 3e-14 52.2 0.9 0.002 17.6 0.0 4.4 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CCM03521.1 - 4.9e-14 51.7 3.7 0.0077 16.3 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CCM03521.1 - 3e-12 45.7 0.7 0.0032 17.1 0.0 4.4 3 0 0 3 3 3 3 Kelch motif Pyridox_oxidase PF01243.15 CCM03522.1 - 1.1e-22 79.8 0.0 2.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 CCM03522.1 - 3.4e-18 64.8 3.4 6.2e-18 64.0 1.5 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 CCM03522.1 - 4.2e-06 27.0 0.6 7.3e-06 26.2 0.1 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Fungal_trans PF04082.13 CCM03523.1 - 4e-13 48.8 0.2 8e-13 47.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AOX PF01786.12 CCM03525.1 - 8.8e-87 289.8 0.0 1.1e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase PH_4 PF15404.1 CCM03526.1 - 1.2e-25 90.1 1.8 1.3e-23 83.4 0.7 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain Ribosom_S12_S23 PF00164.20 CCM03527.1 - 3.6e-42 142.6 1.5 4.4e-42 142.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 zf-Nse PF11789.3 CCM03528.1 - 7.1e-15 54.2 0.0 1.2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Phage_GP20 PF06810.6 CCM03528.1 - 0.012 15.0 4.5 0.033 13.6 3.1 1.7 1 0 0 1 1 1 0 Phage minor structural protein GP20 zf-RING_UBOX PF13445.1 CCM03528.1 - 0.014 15.0 0.2 0.033 13.9 0.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Occludin_ELL PF07303.8 CCM03528.1 - 0.17 12.6 4.9 0.45 11.2 3.3 1.8 1 1 0 1 1 1 0 Occludin homology domain zf-RING_2 PF13639.1 CCM03528.1 - 0.18 11.6 0.4 0.63 9.9 0.2 1.9 2 0 0 2 2 2 0 Ring finger domain SlyX PF04102.7 CCM03528.1 - 0.19 12.0 2.4 0.64 10.4 1.7 1.9 1 0 0 1 1 1 0 SlyX MRP-L47 PF06984.8 CCM03529.1 - 1.5e-21 76.0 3.2 1.7e-21 75.8 1.1 2.0 3 0 0 3 3 3 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) priB_priC PF07445.7 CCM03529.1 - 2.2e-06 27.2 0.8 2.2e-06 27.2 0.6 1.7 2 0 0 2 2 2 1 Primosomal replication protein priB and priC DUF1675 PF07897.6 CCM03529.1 - 0.082 12.7 4.0 0.11 12.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SQS_PSY PF00494.14 CCM03530.1 - 8.4e-54 182.6 0.1 9.7e-54 182.4 0.1 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Amidohydro_5 PF13594.1 CCM03532.1 - 0.0034 17.1 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_71 PF03659.9 CCM03533.1 - 1.1e-96 323.6 6.2 1.4e-96 323.3 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 zf-RING_UBOX PF13445.1 CCM03534.1 - 0.079 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger ANAPC15 PF15243.1 CCM03534.1 - 4.5 7.3 9.8 6.2 6.9 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 HAD_2 PF13419.1 CCM03535.1 - 3e-15 56.8 0.6 6.5e-10 39.4 0.0 3.1 1 1 2 3 3 3 3 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCM03535.1 - 2.7e-06 27.0 0.0 5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCM03535.1 - 0.00017 22.0 0.1 0.035 14.5 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase CS PF04969.11 CCM03536.1 - 2.2e-08 34.5 0.0 7.4e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 CS domain LRR_3 PF07725.7 CCM03536.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Leucine Rich Repeat PP2C PF00481.16 CCM03537.1 - 1.8e-57 194.6 0.8 9.4e-29 100.5 0.1 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 CCM03537.1 - 2e-05 24.4 0.2 2e-05 24.4 0.1 2.2 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) DUF4407 PF14362.1 CCM03537.1 - 0.47 9.3 3.0 0.71 8.7 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Scm3 PF10384.4 CCM03538.1 - 8e-15 54.0 2.5 2.4e-14 52.5 0.1 2.8 2 0 0 2 2 2 1 Centromere protein Scm3 CBM_19 PF03427.8 CCM03540.1 - 0.093 12.5 0.1 0.093 12.5 0.1 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) BUD22 PF09073.5 CCM03541.1 - 9.4e-59 199.5 14.5 1.5e-58 198.9 10.1 1.3 1 1 0 1 1 1 1 BUD22 DIOX_N PF14226.1 CCM03542.1 - 4.7e-28 98.0 0.0 6.9e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM03542.1 - 1.5e-18 66.9 0.0 2.2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TFCD_C PF12612.3 CCM03543.1 - 3.1e-31 108.3 0.2 2e-30 105.6 0.0 2.5 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 CCM03543.1 - 0.00032 20.5 9.0 0.12 12.5 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 CCM03543.1 - 0.0016 18.6 7.8 0.14 12.4 0.1 5.3 4 2 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 CCM03543.1 - 0.13 12.7 14.7 1.4 9.5 0.0 7.5 8 1 1 9 9 9 0 HEAT-like repeat ATP-synt_ab PF00006.20 CCM03544.1 - 9.3e-62 208.3 0.0 1.3e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCM03544.1 - 7.5e-15 55.3 0.1 1.7e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCM03544.1 - 2.5e-11 43.6 0.6 4.4e-11 42.8 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CCM03544.1 - 0.00073 19.3 0.4 0.0016 18.3 0.3 1.5 1 0 0 1 1 1 1 HAS barrel domain Tcp11 PF05794.8 CCM03545.1 - 8.6e-60 202.6 0.0 3e-42 144.8 0.0 3.5 3 1 0 3 3 3 3 T-complex protein 11 Peptidase_S9 PF00326.16 CCM03548.1 - 1.6e-49 168.0 0.2 5.1e-49 166.3 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCM03548.1 - 8.7e-12 45.0 0.0 2.9e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM03548.1 - 1.4e-11 44.7 1.6 6.8e-11 42.4 0.5 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 CCM03548.1 - 0.00048 18.7 0.0 0.079 11.4 0.0 2.4 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) AAA PF00004.24 CCM03549.1 - 8.5e-41 139.2 0.0 1.6e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCM03549.1 - 2.8e-05 24.1 0.1 0.0019 18.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCM03549.1 - 0.00041 20.5 0.4 0.018 15.1 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCM03549.1 - 0.00058 19.5 0.2 0.006 16.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CCM03549.1 - 0.00071 18.6 0.0 0.0015 17.6 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CCM03549.1 - 0.00085 19.2 0.1 0.01 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 CCM03549.1 - 0.0013 17.9 0.1 0.023 13.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 CCM03549.1 - 0.0047 16.7 0.1 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCM03549.1 - 0.0063 15.9 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCM03549.1 - 0.0085 15.8 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCM03549.1 - 0.01 16.6 0.1 0.031 15.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CCM03549.1 - 0.014 14.5 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCM03549.1 - 0.026 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCM03549.1 - 0.035 13.4 1.0 0.48 9.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.1 CCM03549.1 - 0.048 13.2 0.0 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CCM03549.1 - 0.053 12.4 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 CCM03549.1 - 0.076 12.5 0.1 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Motile_Sperm PF00635.21 CCM03552.1 - 1.2e-27 95.7 0.3 1.9e-27 95.0 0.2 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Spc42p PF11544.3 CCM03552.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body component Spc42p FixG_C PF11614.3 CCM03552.1 - 0.026 14.6 0.1 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF756 PF05506.7 CCM03552.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF756) Motile_Sperm PF00635.21 CCM03553.1 - 7.9e-26 89.8 0.4 1e-25 89.5 0.3 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ABC_membrane PF00664.18 CCM03554.1 - 4.2e-91 305.1 22.0 4.8e-48 163.9 4.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCM03554.1 - 3.6e-68 228.1 0.0 2.6e-33 115.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCM03554.1 - 1.5e-14 53.7 0.8 0.0002 20.6 0.0 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCM03554.1 - 3.5e-13 50.1 0.0 0.00013 22.0 0.0 4.2 3 1 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 CCM03554.1 - 1.3e-08 33.8 0.7 0.00091 17.9 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 CCM03554.1 - 7.7e-08 31.7 1.5 0.00076 18.9 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCM03554.1 - 7.9e-07 29.9 0.0 0.077 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCM03554.1 - 3e-06 27.3 1.4 0.028 14.4 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 CCM03554.1 - 1.6e-05 24.1 0.0 0.1 11.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCM03554.1 - 0.00031 20.2 0.2 0.26 10.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 CCM03554.1 - 0.00031 19.9 0.0 0.23 10.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 CCM03554.1 - 0.00033 20.5 0.0 0.58 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCM03554.1 - 0.00045 20.5 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCM03554.1 - 0.00072 19.6 6.5 0.43 10.7 0.1 4.5 5 1 0 5 5 3 2 AAA domain SbcCD_C PF13558.1 CCM03554.1 - 0.001 18.9 1.8 1.7 8.5 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CCM03554.1 - 0.0012 19.2 2.1 0.86 9.8 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 CCM03554.1 - 0.0012 18.4 3.2 2.7 7.5 0.0 4.3 5 0 0 5 5 4 1 AAA domain AAA_28 PF13521.1 CCM03554.1 - 0.002 18.1 1.6 0.71 9.8 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA PF00004.24 CCM03554.1 - 0.0022 18.1 2.9 2.4 8.3 0.2 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCM03554.1 - 0.0029 17.4 0.0 1.6 8.6 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 CCM03554.1 - 0.0031 17.2 0.0 1.8 8.3 0.0 3.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.15 CCM03554.1 - 0.0065 16.1 0.0 0.14 11.8 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase MobB PF03205.9 CCM03554.1 - 0.012 15.3 0.6 5 6.8 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CCM03554.1 - 0.013 15.2 0.3 7.7 6.2 0.1 3.0 3 0 0 3 3 2 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 CCM03554.1 - 0.027 13.9 0.1 10 5.5 0.0 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 CCM03554.1 - 0.039 13.3 2.8 7.4 5.9 0.0 3.5 3 1 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 CCM03554.1 - 0.042 14.0 0.0 3.2 7.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 CCM03554.1 - 0.043 13.7 0.0 14 5.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.13 CCM03554.1 - 0.045 13.2 0.0 3.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 CCM03554.1 - 0.052 13.0 0.1 4.5 6.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2628 PF10947.3 CCM03554.1 - 0.058 13.1 0.1 0.058 13.1 0.1 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF2628) Miro PF08477.8 CCM03554.1 - 0.072 13.5 0.0 18 5.8 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein AAA_15 PF13175.1 CCM03554.1 - 0.08 11.9 0.0 2.4 7.1 0.0 2.4 3 0 0 3 3 2 0 AAA ATPase domain NB-ARC PF00931.17 CCM03554.1 - 0.16 10.7 0.1 3.9 6.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.15 CCM03554.1 - 0.7 8.5 7.5 0.67 8.5 0.0 2.8 3 0 0 3 3 2 0 G-protein alpha subunit Pkinase PF00069.20 CCM03555.1 - 4.4e-69 232.5 0.0 5.4e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03555.1 - 4.9e-31 107.7 0.0 6.6e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCM03555.1 - 1.2e-09 38.5 1.3 2.7e-09 37.4 0.9 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCM03555.1 - 9.7e-05 21.4 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCM03555.1 - 0.016 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM03555.1 - 0.025 14.2 0.2 0.065 12.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM03555.1 - 0.14 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase G-patch PF01585.18 CCM03556.1 - 2e-06 27.4 0.8 1.3e-05 24.8 0.8 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CCM03556.1 - 0.026 14.3 1.8 0.13 12.1 0.6 2.4 2 0 0 2 2 2 0 DExH-box splicing factor binding site F-box-like PF12937.2 CCM03557.1 - 1.9e-11 43.5 0.1 1.1e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM03557.1 - 0.0033 17.0 0.1 0.023 14.3 0.1 2.6 1 0 0 1 1 1 1 F-box domain PQ-loop PF04193.9 CCM03558.1 - 6.2e-16 57.6 0.8 6.2e-16 57.6 0.5 2.1 3 0 0 3 3 3 1 PQ loop repeat PEMT PF04191.8 CCM03558.1 - 0.086 12.9 0.8 6.1 7.0 0.3 2.4 2 0 0 2 2 2 0 Phospholipid methyltransferase AWPM-19 PF05512.6 CCM03558.1 - 0.11 12.4 1.7 0.89 9.5 1.2 2.1 1 1 0 1 1 1 0 AWPM-19-like family NfeD PF01957.13 CCM03558.1 - 0.28 11.2 2.6 3.2 7.8 0.3 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding PepSY_TM_1 PF13172.1 CCM03558.1 - 1 9.1 3.8 1.8 8.4 0.2 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix Band_7 PF01145.20 CCM03559.1 - 2.5e-19 69.8 1.0 3.9e-19 69.2 0.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family MutS_V PF00488.16 CCM03560.1 - 3.8e-50 170.4 0.0 2e-49 168.1 0.0 2.1 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCM03560.1 - 2.4e-34 118.9 0.0 5.7e-34 117.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain III DAP3 PF10236.4 CCM03560.1 - 0.018 13.9 0.2 0.95 8.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 MutS_IV PF05190.13 CCM03560.1 - 0.028 14.5 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV AAA_22 PF13401.1 CCM03560.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCM03560.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.22 CCM03561.1 - 2.5e-40 136.1 4.1 2.1e-13 49.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NCA2 PF08637.5 CCM03563.1 - 4.7e-72 242.3 0.0 7.9e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 PRP1_N PF06424.7 CCM03564.1 - 9.9e-33 113.2 2.5 9.9e-33 113.2 1.8 2.2 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CCM03564.1 - 3.2e-27 92.5 32.1 0.036 14.6 0.4 14.6 5 5 10 15 15 15 9 Tetratricopeptide repeat TPR_16 PF13432.1 CCM03564.1 - 8.8e-24 83.5 22.4 2e-06 28.2 0.2 9.0 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCM03564.1 - 3.3e-14 52.9 22.5 0.035 14.4 0.0 9.6 7 4 3 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCM03564.1 - 1.5e-09 37.0 6.5 0.32 11.0 0.0 8.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCM03564.1 - 3e-07 29.9 9.5 0.014 15.0 0.2 7.1 5 2 2 7 7 7 2 TPR repeat TPR_6 PF13174.1 CCM03564.1 - 3.4e-07 30.2 6.3 1.1 9.9 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCM03564.1 - 1.4e-06 28.1 1.5 0.25 11.3 0.0 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCM03564.1 - 0.00039 19.9 0.1 0.61 9.9 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCM03564.1 - 0.0038 16.7 0.1 15 5.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 CCM03564.1 - 0.9 8.2 8.4 0.6 8.7 0.1 4.0 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 CCM03564.1 - 3.9 7.3 12.5 12 5.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat CsbD PF05532.7 CCM03565.1 - 0.0036 16.9 3.9 0.012 15.2 2.7 1.9 1 0 0 1 1 1 1 CsbD-like CMAS PF02353.15 CCM03566.1 - 7.7e-45 153.0 1.7 5.2e-32 111.0 0.7 3.8 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CCM03566.1 - 0.00013 22.4 0.2 0.00042 20.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM03566.1 - 0.0004 20.1 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCM03566.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain GCD14 PF08704.5 CCM03566.1 - 0.007 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 CCM03566.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CCM03566.1 - 0.025 14.6 0.1 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCM03566.1 - 0.063 13.7 0.1 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 CCM03566.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RIX1 PF08167.7 CCM03567.1 - 2.5e-05 24.0 1.5 7.4e-05 22.4 1.0 1.9 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 CCM03567.1 - 0.00076 19.9 0.5 1.6 9.2 0.0 3.6 1 1 1 2 2 2 2 HEAT-like repeat Rif1_N PF12231.3 CCM03567.1 - 0.0013 17.8 1.4 0.0026 16.7 0.9 1.4 1 1 0 1 1 1 1 Rap1-interacting factor 1 N terminal HEAT PF02985.17 CCM03567.1 - 0.0054 16.6 0.3 0.094 12.8 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 CCM03567.1 - 0.0087 16.3 2.1 0.37 11.0 0.6 3.8 3 1 0 3 3 3 1 HEAT repeats CsbD PF05532.7 CCM03569.1 - 0.0031 17.1 2.9 0.0061 16.2 2.0 1.5 1 0 0 1 1 1 1 CsbD-like Toxin_62 PF15540.1 CCM03569.1 - 0.2 11.8 4.9 0.32 11.1 3.4 1.4 1 1 0 1 1 1 0 Putative toxin 62 Asp PF00026.18 CCM03570.1 - 4.6e-43 147.6 0.1 1.6e-42 145.8 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCM03570.1 - 0.00027 21.3 1.8 0.0049 17.3 0.8 2.8 2 1 0 2 2 2 1 Aspartyl protease PARP PF00644.15 CCM03572.1 - 4.8e-06 26.1 1.0 1.4e-05 24.6 0.5 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ribosomal_L5 PF00281.14 CCM03572.1 - 0.11 12.3 0.6 22 4.9 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein L5 PARP PF00644.15 CCM03573.1 - 0.0001 21.7 0.2 0.00027 20.4 0.1 1.8 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF2638 PF10937.3 CCM03575.1 - 5.1e-13 50.0 1.1 1.8e-12 48.2 0.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) SR-25 PF10500.4 CCM03575.1 - 0.16 11.4 3.4 0.18 11.2 2.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Proteasome PF00227.21 CCM03576.1 - 9.7e-30 103.2 0.1 2.4e-29 101.9 0.1 1.6 1 1 0 1 1 1 1 Proteasome subunit RNA_pol_Rpb1_5 PF04998.12 CCM03577.1 - 1.6e-96 322.8 0.1 2.3e-96 322.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CCM03577.1 - 1.5e-90 303.9 0.0 2.1e-90 303.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CCM03577.1 - 2e-66 223.0 0.0 4e-66 222.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCM03577.1 - 8.5e-40 136.0 0.0 1.3e-38 132.2 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCM03577.1 - 5.2e-31 106.5 0.0 1.3e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 CCM03577.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 InsA N-terminal domain DUF2786 PF10979.3 CCM03577.1 - 0.086 12.5 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) IRF PF00605.12 CCM03577.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor GIT_SHD PF08518.6 CCM03578.1 - 5.3e-24 83.2 7.8 2e-13 49.4 1.6 3.3 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT Peptidase_U57 PF05582.7 CCM03578.1 - 0.02 13.9 1.3 0.042 12.8 0.9 1.6 1 0 0 1 1 1 0 YabG peptidase U57 Tropomyosin PF00261.15 CCM03578.1 - 1.6 7.7 35.6 4.3 6.3 24.6 1.7 1 0 0 1 1 1 0 Tropomyosin NPV_P10 PF05531.7 CCM03578.1 - 4.7 7.5 7.2 4 7.7 0.1 4.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Lipase_3 PF01764.20 CCM03579.1 - 4.6e-15 55.4 0.0 1.1e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_5 PF12695.2 CCM03579.1 - 0.049 13.3 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Spt4 PF06093.8 CCM03580.1 - 1.5e-30 104.8 0.2 1.8e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger CASP_C PF08172.7 CCM03581.1 - 0.13 11.3 0.4 0.48 9.4 0.2 1.9 2 0 0 2 2 2 0 CASP C terminal Mito_carr PF00153.22 CCM03583.1 - 9.3e-16 57.3 0.0 1.6e-08 34.1 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial carrier protein ATP-synt_8 PF00895.15 CCM03583.1 - 2.9 8.1 6.4 5.5 7.2 0.1 3.5 4 0 0 4 4 4 0 ATP synthase protein 8 SNF2_N PF00176.18 CCM03584.1 - 7.7e-58 195.6 0.1 1.1e-57 195.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM03584.1 - 2.3e-14 53.0 0.0 6.8e-14 51.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM03584.1 - 4.2e-06 26.7 0.0 8.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_3 PF12836.2 CCM03584.1 - 0.024 14.5 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sybindin PF04099.7 CCM03585.1 - 2.2e-15 56.5 0.0 3.5e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family ABC2_membrane_4 PF12730.2 CCM03585.1 - 0.049 12.8 0.9 0.072 12.2 0.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Ank_2 PF12796.2 CCM03586.1 - 1.7e-06 28.2 0.1 3.2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCM03586.1 - 1.9e-05 25.0 0.3 0.0099 16.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCM03586.1 - 0.0062 16.2 0.0 0.018 14.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 CCM03586.1 - 0.016 15.4 0.1 0.035 14.3 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM03586.1 - 0.082 13.1 0.2 0.71 10.2 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat DUF1168 PF06658.7 CCM03587.1 - 7.2e-40 135.7 12.7 7.2e-40 135.7 8.8 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1168) Ribosomal_S8e PF01201.17 CCM03587.1 - 1.4e-34 119.0 8.0 1.4e-34 119.0 5.6 2.7 2 1 0 2 2 2 1 Ribosomal protein S8e Yip1 PF04893.12 CCM03588.1 - 0.00013 21.4 2.0 0.00021 20.8 1.4 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1746 PF08508.5 CCM03590.1 - 0.00013 21.8 2.0 0.00046 20.1 1.0 2.1 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DUF2528 PF10800.3 CCM03591.1 - 0.032 14.6 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) Rad10 PF03834.9 CCM03593.1 - 1.1e-23 82.7 0.0 2.2e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Amidohydro_4 PF13147.1 CCM03593.1 - 9.6e-13 48.7 0.6 9.6e-13 48.7 0.4 2.5 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 CCM03593.1 - 9.6e-13 47.7 0.2 3e-10 39.7 0.1 2.6 2 0 0 2 2 2 2 Amidohydrolase HHH_5 PF14520.1 CCM03593.1 - 7.2e-09 35.6 0.0 7.3e-08 32.4 0.0 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain HHH_3 PF12836.2 CCM03593.1 - 0.00062 19.6 0.0 0.0022 17.8 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 CCM03593.1 - 0.0042 16.9 0.0 0.02 14.7 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif Amidohydro_1 PF01979.15 CCM03593.1 - 0.0045 16.6 0.1 4.1 6.9 0.0 3.1 3 1 0 3 3 3 2 Amidohydrolase family TRP PF06011.7 CCM03594.1 - 2.4e-44 151.6 15.3 3.7e-44 151.0 10.6 1.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel GP41 PF00517.12 CCM03594.1 - 1.3 8.5 3.3 4.9 6.6 1.2 2.2 2 0 0 2 2 2 0 Retroviral envelope protein OSCP PF00213.13 CCM03595.1 - 1.1e-40 139.3 1.3 1.2e-40 139.1 0.9 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Amidohydro_4 PF13147.1 CCM03596.1 - 6.8e-20 72.2 3.2 1e-19 71.6 0.4 2.5 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 CCM03596.1 - 2e-12 46.7 0.3 2e-09 37.1 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 CCM03596.1 - 3.4e-11 43.4 0.0 8.9e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CCM03596.1 - 2.9e-06 26.7 0.8 0.00011 21.5 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Hist_deacetyl PF00850.14 CCM03597.1 - 6.3e-91 304.8 0.1 1.1e-90 304.0 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CCM03597.1 - 4.2e-22 78.4 0.0 1.2e-21 76.9 0.0 1.7 2 0 0 2 2 2 1 Arb2 domain DUF3089 PF11288.3 CCM03597.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) HET PF06985.6 CCM03600.1 - 1.5e-12 47.9 4.9 3.8e-11 43.3 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.1 CCM03601.1 - 0.016 15.5 6.1 0.017 15.4 0.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM03601.1 - 0.23 11.8 0.3 0.23 11.8 0.2 2.5 2 1 0 2 2 2 0 Zinc finger, C2H2 type DUF1752 PF08550.5 CCM03602.1 - 6.8e-13 47.9 2.8 1.5e-12 46.8 1.9 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.3 CCM03602.1 - 1.1e-12 47.7 0.7 1.1e-12 47.7 0.5 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3295) 2OG-FeII_Oxy PF03171.15 CCM03603.1 - 2.1e-11 43.9 0.0 3.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CCM03603.1 - 0.0008 19.9 0.0 0.016 15.7 0.0 2.7 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal OppC_N PF12911.2 CCM03604.1 - 2 7.8 8.1 12 5.3 0.1 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DnaJ PF00226.26 CCM03605.1 - 1.4e-17 63.2 0.2 2.6e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCM03605.1 - 2.2e-07 30.6 0.1 4e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain Sigma70_ner PF04546.8 CCM03605.1 - 0.02 14.4 1.3 0.02 14.4 0.9 2.3 2 1 1 3 3 3 0 Sigma-70, non-essential region MIP-T3 PF10243.4 CCM03605.1 - 5.9 5.2 24.4 8.2 4.7 16.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Drf_GBD PF06371.8 CCM03607.1 - 3.1e-16 59.2 0.7 3.2e-15 55.9 0.5 2.0 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain WD40 PF00400.27 CCM03608.1 - 5.8e-22 76.7 12.1 7.3e-07 28.8 0.1 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 CCM03608.1 - 0.033 12.3 0.2 0.48 8.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 eIF3_subunit PF08597.5 CCM03609.1 - 1.9e-47 161.9 15.2 2.1e-47 161.7 10.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2935 PF11155.3 CCM03609.1 - 0.0057 16.7 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) DUF1227 PF06777.6 CCM03609.1 - 0.045 13.4 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) Bindin PF02084.10 CCM03609.1 - 0.42 10.6 5.1 2.1 8.3 0.1 3.0 2 1 1 3 3 3 0 Bindin GMC_oxred_N PF00732.14 CCM03610.1 - 2.6e-41 141.7 0.0 3.9e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM03610.1 - 1.8e-38 132.0 0.1 4.8e-38 130.6 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Kelch_4 PF13418.1 CCM03611.1 - 7.8e-30 102.3 13.5 2.3e-06 27.2 0.0 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 CCM03611.1 - 4.5e-19 68.0 22.0 2.9e-05 24.1 0.1 7.2 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CCM03611.1 - 3.8e-16 58.6 6.8 0.00035 20.4 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 CCM03611.1 - 9.5e-16 57.2 15.4 0.00023 21.1 0.1 6.0 3 2 2 5 5 5 5 Kelch motif Kelch_2 PF07646.10 CCM03611.1 - 1.2e-12 47.0 10.0 0.0028 17.3 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CCM03611.1 - 1e-10 40.9 0.0 0.0088 15.5 0.0 5.1 5 0 0 5 5 5 2 Kelch motif ACBP PF00887.14 CCM03612.1 - 7.4e-25 86.4 0.0 1.2e-24 85.7 0.0 1.3 1 1 0 1 1 1 1 Acyl CoA binding protein PH PF00169.24 CCM03613.1 - 1.3e-26 92.8 0.0 3.3e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 CCM03613.1 - 3.1e-10 40.2 3.9 0.0012 19.1 0.1 4.5 4 1 0 4 4 4 2 Pleckstrin homology domain PH_8 PF15409.1 CCM03613.1 - 6.7e-06 26.0 0.0 0.0029 17.6 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 CCM03613.1 - 0.00041 20.1 0.0 0.3 10.9 0.0 3.8 4 1 0 4 4 4 1 PH domain Mcp5_PH PF12814.2 CCM03613.1 - 0.0066 16.3 0.7 3.1 7.7 0.0 3.1 3 1 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 CCM03613.1 - 0.011 15.9 0.1 0.15 12.1 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain Rep_fac-A_C PF08646.5 CCM03614.1 - 2.3e-45 153.8 4.2 9.3e-44 148.6 0.4 2.6 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 CCM03614.1 - 1.7e-20 72.6 0.0 3.5e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 CCM03614.1 - 1.1e-12 47.6 2.1 1.7e-11 43.7 0.2 2.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 CCM03614.1 - 0.0034 17.4 3.5 0.0036 17.3 0.3 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF223 Tim54 PF11711.3 CCM03615.1 - 1.7e-65 221.1 0.5 1.7e-64 217.7 0.3 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF2198 PF09964.4 CCM03615.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) FAM219A PF15260.1 CCM03616.1 - 0.0012 19.1 1.5 0.0015 18.8 0.1 1.9 2 0 0 2 2 2 1 Protein family FAM219A Sec63 PF02889.11 CCM03617.1 - 7.1e-44 150.2 0.4 1.4e-43 149.3 0.3 1.4 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.26 CCM03617.1 - 1.7e-08 34.2 0.0 3.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCM03617.1 - 4.2e-07 29.6 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.1 CCM03617.1 - 0.026 14.6 0.0 0.089 12.9 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain CKS PF01111.14 CCM03618.1 - 5.1e-36 122.3 0.2 6.8e-36 121.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3822 PF12864.2 CCM03618.1 - 0.0064 15.7 0.0 0.0078 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3822) PCI_Csn8 PF10075.4 CCM03620.1 - 1.2e-14 54.2 0.0 2.4e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CCM03620.1 - 2.9e-05 23.7 0.1 3.8e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF1681 PF07933.9 CCM03621.1 - 3e-52 176.4 0.0 3.5e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Pkinase PF00069.20 CCM03623.1 - 1.7e-45 155.1 0.0 2.3e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03623.1 - 4.2e-13 48.9 0.0 6.1e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM03623.1 - 0.011 15.5 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CCM03623.1 - 0.013 14.4 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CCM03623.1 - 0.047 13.0 0.3 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family NIF PF03031.13 CCM03624.1 - 1.2e-20 73.7 0.0 1.9e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 CCM03624.1 - 2.2e-06 26.9 0.0 5.9e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family NUDIX PF00293.23 CCM03625.1 - 2.5e-11 43.3 0.0 3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain COesterase PF00135.23 CCM03627.1 - 2.3e-67 227.9 0.0 3e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM03627.1 - 1.9e-10 40.7 0.3 3.5e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM03627.1 - 0.01 15.0 0.1 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 CCM03627.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.15 CCM03627.1 - 0.061 12.7 0.7 0.32 10.3 0.5 1.9 1 1 0 1 1 1 0 Putative esterase CwfJ_C_1 PF04677.10 CCM03628.1 - 4.1e-29 100.7 0.0 7.9e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CCM03628.1 - 1.5e-19 70.2 0.0 2.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 CCM03628.1 - 2.4e-17 62.0 12.8 5.3e-07 29.0 1.0 3.5 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 CCM03628.1 - 4.6e-08 32.6 16.1 0.00017 21.3 0.2 4.2 4 0 0 4 4 4 3 Zinc knuckle eIF3g PF12353.3 CCM03628.1 - 1.5e-06 28.1 9.5 0.2 11.5 0.5 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor 3 subunit G HIT PF01230.18 CCM03628.1 - 0.028 14.9 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 HIT domain zf-CCHC_3 PF13917.1 CCM03628.1 - 1.3 8.7 6.9 29 4.4 0.0 3.3 2 1 1 3 3 3 0 Zinc knuckle DUF4428 PF14471.1 CCM03628.1 - 1.4 8.6 6.0 9.8 6.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ANAPC15 PF15243.1 CCM03629.1 - 0.0011 18.9 3.5 0.0011 18.9 2.4 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 15 Apc15p PF05841.6 CCM03629.1 - 0.02 15.6 0.3 0.047 14.4 0.0 1.7 1 1 1 2 2 2 0 Apc15p protein Na_trans_assoc PF06512.8 CCM03629.1 - 1.1 9.2 9.0 1.4 8.8 6.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Arginase PF00491.16 CCM03630.1 - 1.7e-77 260.4 0.0 2.1e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family HSP20 PF00011.16 CCM03631.1 - 8.7e-24 83.3 0.1 1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 CCM03631.1 - 0.0028 17.3 0.2 0.03 14.0 0.0 2.1 2 0 0 2 2 2 1 BON domain CS PF04969.11 CCM03631.1 - 0.0092 16.5 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF4097 PF13349.1 CCM03631.1 - 0.047 13.2 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) HMA PF00403.21 CCM03631.1 - 0.048 13.8 0.1 0.082 13.0 0.0 1.5 1 1 0 1 1 1 0 Heavy-metal-associated domain EF-hand_6 PF13405.1 CCM03633.1 - 1.5e-11 43.1 2.0 2.6e-06 26.8 0.1 3.0 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CCM03633.1 - 9.6e-11 40.1 4.9 6.6e-06 25.0 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CCM03633.1 - 1.9e-10 40.7 0.5 3.2e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CCM03633.1 - 5.7e-06 25.4 0.5 0.0039 16.4 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CCM03633.1 - 0.0021 17.6 6.4 0.43 10.2 0.2 2.9 2 2 1 3 3 3 2 EF-hand domain pair PTCB-BRCT PF12738.2 CCM03635.1 - 1.4e-10 40.8 0.3 2.4e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 twin BRCT domain NIF PF03031.13 CCM03635.1 - 1.3e-09 37.9 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.21 CCM03635.1 - 7.4e-07 29.2 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BSP PF04450.7 CCM03636.1 - 1.9e-64 216.9 0.0 2.2e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 CCM03636.1 - 1.8e-06 28.0 0.2 2.8e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 CCM03636.1 - 0.00034 20.3 0.1 0.00067 19.3 0.1 1.5 1 0 0 1 1 1 1 SprT-like family HLH PF00010.21 CCM03637.1 - 8.7e-08 31.7 0.0 1.7e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain SNF2_N PF00176.18 CCM03639.1 - 1.2e-54 185.1 0.0 2.7e-54 183.9 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM03639.1 - 3.7e-13 49.1 0.0 9.2e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 CCM03639.1 - 1.4e-10 41.0 0.0 9.4e-10 38.3 0.0 2.3 2 0 0 2 2 2 1 HIRAN domain DEAD PF00270.24 CCM03639.1 - 1.3e-05 24.7 0.0 5.9e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Cpn60_TCP1 PF00118.19 CCM03640.1 - 3e-140 468.0 0.1 3.4e-140 467.9 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.11 CCM03641.1 - 6.9e-23 80.9 16.7 1.1e-22 80.2 11.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 CCM03642.1 - 4.8e-23 81.4 14.2 7.6e-23 80.7 9.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2631 PF10939.3 CCM03642.1 - 0.023 14.5 0.1 0.07 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) WLM PF08325.5 CCM03643.1 - 5.3e-51 173.1 1.0 4.4e-50 170.1 0.0 2.2 2 1 0 2 2 2 1 WLM domain Bot1p PF12298.3 CCM03643.1 - 1.3e-27 96.8 0.1 3.6e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF45 PF01863.12 CCM03643.1 - 0.0034 17.1 1.3 0.011 15.5 0.3 2.3 3 0 0 3 3 3 1 Protein of unknown function DUF45 DUF4349 PF14257.1 CCM03643.1 - 3.8 6.6 11.5 0.42 9.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Methyltransf_11 PF08241.7 CCM03644.1 - 4.9e-12 46.1 0.0 8.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM03644.1 - 8.5e-09 35.3 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM03644.1 - 1.2e-07 31.9 0.0 2.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM03644.1 - 1.1e-06 29.0 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM03644.1 - 2.5e-06 27.1 0.0 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM03644.1 - 3.5e-06 27.5 0.0 6.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM03644.1 - 2.6e-05 24.2 0.0 5.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM03644.1 - 2.8e-05 23.3 0.0 4.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 CCM03644.1 - 0.00043 20.3 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.10 CCM03644.1 - 0.021 14.4 0.0 0.098 12.2 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.15 CCM03644.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Sas10_Utp3 PF04000.10 CCM03645.1 - 4.4e-17 62.0 0.1 1e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Lin-8 PF03353.10 CCM03645.1 - 1.3 8.2 5.1 2.4 7.3 3.5 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist F-box-like PF12937.2 CCM03646.1 - 1.7e-07 30.8 0.8 9.5e-07 28.4 0.6 2.4 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.1 CCM03646.1 - 1.2e-05 24.8 7.3 4.9 7.5 0.1 8.3 10 0 0 10 10 10 1 Leucine Rich repeat F-box PF00646.28 CCM03646.1 - 0.0063 16.1 4.9 0.019 14.6 0.1 2.8 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 CCM03646.1 - 0.024 14.2 6.0 1.7 8.3 0.0 4.8 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCM03646.1 - 0.025 14.5 10.8 8.4 6.8 0.0 6.8 7 1 0 7 7 7 0 Leucine Rich Repeat YABBY PF04690.8 CCM03647.1 - 1e-06 29.1 0.0 1.1e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 YABBY protein FlgD PF03963.9 CCM03647.1 - 0.0034 17.4 0.1 0.0045 17.0 0.1 1.1 1 0 0 1 1 1 1 Flagellar hook capping protein - N-terminal region HMG_box PF00505.14 CCM03647.1 - 0.072 13.3 0.6 0.1 12.9 0.4 1.2 1 0 0 1 1 1 0 HMG (high mobility group) box PA PF02225.17 CCM03648.1 - 3.4e-14 52.3 0.0 5.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_2 PF13639.1 CCM03648.1 - 9.3e-13 47.7 4.0 2e-12 46.6 2.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCM03648.1 - 8.8e-06 25.3 2.0 1.6e-05 24.5 1.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCM03648.1 - 1.7e-05 24.7 4.5 3.4e-05 23.7 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCM03648.1 - 5.2e-05 22.8 2.9 9.4e-05 22.0 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCM03648.1 - 0.0001 21.9 3.0 0.0002 20.9 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCM03648.1 - 0.00014 21.9 6.5 0.0003 20.8 4.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger DUF2910 PF11139.3 CCM03648.1 - 0.037 13.1 0.3 0.065 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) zf-Apc11 PF12861.2 CCM03648.1 - 0.054 13.3 2.2 0.19 11.6 1.6 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Corona_S2 PF01601.11 CCM03648.1 - 0.12 10.5 0.4 0.16 10.0 0.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein BatD PF13584.1 CCM03648.1 - 0.19 10.3 0.1 0.29 9.6 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance Sec1 PF00995.18 CCM03649.1 - 1.6e-117 393.5 0.0 1.8e-117 393.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MobC PF05713.6 CCM03649.1 - 0.075 13.0 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) cNMP_binding PF00027.24 CCM03650.1 - 4e-40 135.5 0.0 1.5e-18 66.4 0.0 4.9 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 CCM03650.1 - 3.1e-17 63.2 5.7 3e-15 56.7 3.9 2.8 1 1 0 1 1 1 1 Patatin-like phospholipase Chitin_synth_1 PF01644.12 CCM03651.1 - 1.4e-75 252.6 0.3 2e-75 252.0 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 CCM03651.1 - 2.2e-25 89.0 0.1 3.2e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 CCM03651.1 - 5.6e-23 80.4 0.0 1.5e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 CCM03651.1 - 6.7e-08 32.6 0.0 2.2e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCM03651.1 - 2.5e-07 30.6 8.3 2e-06 27.6 5.8 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Pkinase PF00069.20 CCM03652.1 - 1.7e-35 122.4 0.0 2.6e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03652.1 - 2.3e-12 46.5 0.0 3.4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCM03652.1 - 0.07 11.9 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ICL PF00463.16 CCM03653.1 - 2.5e-188 626.5 0.0 2.9e-188 626.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCM03653.1 - 2e-10 40.3 0.1 7.8e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Terpene_synth_C PF03936.11 CCM03654.1 - 1.4e-15 57.2 0.0 1.9e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF457 PF04307.9 CCM03655.1 - 0.13 11.6 2.7 0.21 10.9 1.8 1.6 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Homeobox PF00046.24 CCM03656.1 - 1.3e-47 159.1 9.8 7.7e-16 57.4 0.3 3.3 3 0 0 3 3 3 3 Homeobox domain Homeobox_KN PF05920.6 CCM03656.1 - 8.9e-14 50.9 4.8 3.1e-05 23.5 0.0 3.9 4 0 0 4 4 4 3 Homeobox KN domain HTH_3 PF01381.17 CCM03656.1 - 0.072 12.9 0.1 9.8 6.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix Homez PF11569.3 CCM03656.1 - 0.076 12.0 0.6 9.1 5.4 0.0 3.0 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Fumble PF03630.9 CCM03657.1 - 3.3e-118 394.4 0.0 1.5e-90 303.5 0.1 2.7 2 1 0 2 2 2 2 Fumble Adaptin_N PF01602.15 CCM03658.1 - 1.8e-115 386.2 0.0 2.5e-115 385.7 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CCM03658.1 - 1.8e-57 193.3 0.9 4.3e-57 192.1 0.6 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CCM03658.1 - 3.1e-13 49.7 2.4 0.00043 20.4 0.1 6.0 2 2 5 7 7 7 4 HEAT repeats HEAT PF02985.17 CCM03658.1 - 0.0027 17.6 6.2 4.4 7.6 0.1 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.11 CCM03658.1 - 0.21 12.1 2.0 42 5.0 0.0 4.6 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Cnd1 PF12717.2 CCM03658.1 - 0.22 11.3 5.7 0.91 9.3 0.1 3.3 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CCM03658.1 - 0.35 10.7 3.3 49 3.9 0.0 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Peptidase_M76 PF09768.4 CCM03659.1 - 4.2e-67 224.9 2.4 5.9e-67 224.4 1.6 1.2 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_MA_2 PF13485.1 CCM03659.1 - 0.056 13.4 0.2 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily SprT-like PF10263.4 CCM03659.1 - 0.33 10.5 4.4 0.47 10.1 1.8 1.9 1 1 1 2 2 2 0 SprT-like family WLM PF08325.5 CCM03659.1 - 0.66 9.8 2.8 0.42 10.4 0.1 1.9 2 0 0 2 2 2 0 WLM domain Pex14_N PF04695.8 CCM03659.1 - 2 8.4 9.7 0.9 9.5 4.7 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ECH PF00378.15 CCM03660.1 - 4.1e-33 114.5 0.0 5.8e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2431 PF10354.4 CCM03661.1 - 5.8e-37 127.2 0.0 1.7e-36 125.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) RAMP4 PF06624.7 CCM03662.1 - 7.7e-06 25.3 0.1 9.8e-06 25.0 0.1 1.2 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 WD40 PF00400.27 CCM03663.1 - 3.8e-34 115.3 9.4 1.8e-09 37.1 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCM03663.1 - 1.2e-27 95.5 0.4 3e-27 94.3 0.3 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex INO80_Ies4 PF08193.6 CCM03664.1 - 0.00021 21.2 1.1 0.00021 21.2 0.8 2.7 3 1 1 4 4 4 1 INO80 complex subunit Ies4 PBP1_TM PF14812.1 CCM03664.1 - 0.2 11.9 7.1 0.57 10.5 4.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 CCM03664.1 - 0.45 10.7 8.8 0.95 9.7 6.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TMEM154 PF15102.1 CCM03664.1 - 1.3 8.7 4.3 0.4 10.3 0.6 1.9 2 0 0 2 2 2 0 TMEM154 protein family RNA_pol_3_Rpc31 PF11705.3 CCM03664.1 - 2.1 8.2 8.7 4.7 7.0 6.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleoplasmin PF03066.10 CCM03664.1 - 2.7 7.4 6.8 4.5 6.7 4.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Dopey_N PF04118.9 CCM03665.1 - 2.3e-110 368.1 0.3 3.9e-109 364.1 0.0 2.8 2 0 0 2 2 2 1 Dopey, N-terminal Cohesin_HEAT PF12765.2 CCM03665.1 - 0.014 15.3 2.2 0.091 12.7 0.3 3.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion EF-hand_6 PF13405.1 CCM03666.1 - 2.5e-09 36.2 0.3 0.001 18.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CCM03666.1 - 6.8e-08 32.5 2.3 2.1e-07 30.9 0.5 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CCM03666.1 - 1.3e-06 27.5 0.2 0.0019 17.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 CCM03666.1 - 7.5e-06 24.8 0.2 0.00064 18.8 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CCM03666.1 - 0.0011 18.5 0.6 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CCM03666.1 - 0.0075 16.2 0.3 0.08 12.9 0.2 2.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region ABC2_membrane PF01061.19 CCM03667.1 - 1.9e-65 219.9 54.7 3.1e-35 121.2 16.2 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 CCM03667.1 - 4.4e-33 114.4 0.0 4.4e-15 56.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCM03667.1 - 1.4e-19 69.6 0.3 6.2e-14 51.5 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CCM03667.1 - 1.3e-07 31.5 0.0 4.7e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 CCM03667.1 - 1.9e-06 27.4 0.0 0.047 13.1 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CCM03667.1 - 1.1e-05 25.3 0.1 0.11 12.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CCM03667.1 - 1.3e-05 25.3 0.2 0.32 11.1 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CCM03667.1 - 0.00012 21.6 0.0 0.13 11.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 CCM03667.1 - 0.0016 18.4 0.6 0.82 9.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCM03667.1 - 0.0016 17.6 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 CCM03667.1 - 0.0055 16.3 0.5 2 8.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CCM03667.1 - 0.0073 17.1 0.0 1.4 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCM03667.1 - 0.0085 16.4 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCM03667.1 - 0.013 15.0 0.4 0.065 12.7 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.14 CCM03667.1 - 0.028 13.6 0.0 0.77 8.9 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CCM03667.1 - 0.029 14.2 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 CCM03667.1 - 0.044 13.9 0.0 14 5.9 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 CCM03667.1 - 0.078 12.9 0.0 3.9 7.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 CCM03667.1 - 0.11 11.8 0.5 2.2 7.6 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 CCM03667.1 - 0.16 11.4 0.1 17 4.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF4615 PF15393.1 CCM03667.1 - 0.2 11.9 0.3 0.65 10.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) AAA_19 PF13245.1 CCM03667.1 - 0.22 11.3 0.8 21 4.9 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 CCM03667.1 - 1.3 8.9 5.1 8.6 6.2 0.4 3.4 3 1 0 3 3 3 0 AAA ATPase domain Prefoldin_2 PF01920.15 CCM03668.1 - 1.2e-15 57.1 5.8 1.5e-15 56.8 4.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 CCM03668.1 - 0.00096 19.0 0.8 0.00096 19.0 0.5 1.9 2 0 0 2 2 2 1 Tropomyosin like DUF4200 PF13863.1 CCM03668.1 - 0.79 9.6 7.5 3.5 7.5 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin PF02996.12 CCM03668.1 - 3.1 7.4 8.8 5.2 6.7 1.1 2.6 2 1 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 CCM03668.1 - 5 7.0 11.1 0.41 10.4 2.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Calreticulin PF00262.13 CCM03669.1 - 1.6e-151 504.1 10.8 1.6e-151 504.1 7.5 1.7 2 0 0 2 2 2 1 Calreticulin family GTP_EFTU PF00009.22 CCM03669.1 - 3.7e-43 147.1 0.0 6.5e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCM03669.1 - 7.3e-25 86.8 0.0 2.5e-24 85.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CCM03669.1 - 3e-20 71.8 0.0 8.6e-20 70.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCM03669.1 - 6.1e-08 32.6 0.0 1.4e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCM03669.1 - 1.6e-06 28.0 0.1 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 CCM03669.1 - 6.7e-06 25.8 0.0 2.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 CCM03669.1 - 0.0026 18.2 0.2 0.0056 17.1 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CCM03669.1 - 0.022 13.9 0.1 0.055 12.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GBP PF02263.14 CCM03669.1 - 0.16 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain DSHCT PF08148.7 CCM03670.1 - 1e-53 181.2 0.2 1.9e-53 180.4 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCM03670.1 - 3.6e-22 78.6 0.1 1e-21 77.1 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 CCM03670.1 - 2e-15 56.7 0.0 2.7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 CCM03670.1 - 9.6e-06 25.3 0.1 3.5e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM03670.1 - 0.023 14.5 0.1 0.14 11.9 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3275 PF11679.3 CCM03671.1 - 0.32 10.5 1.7 0.54 9.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Methyltransf_23 PF13489.1 CCM03672.1 - 5e-05 23.0 0.0 0.077 12.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain FtsJ PF01728.14 CCM03672.1 - 0.0018 18.3 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CCM03672.1 - 0.14 12.7 0.0 8.5 6.9 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 CCM03673.1 - 5.9e-07 28.5 8.9 7.3e-07 28.2 6.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CCM03673.1 - 0.0093 14.4 5.3 0.012 14.0 3.7 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein SH3_9 PF14604.1 CCM03675.1 - 1.4e-05 24.5 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCM03675.1 - 6.6e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCM03675.1 - 0.0025 17.2 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain F-box PF00646.28 CCM03676.1 - 0.00084 18.9 0.9 0.0057 16.2 0.6 2.5 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCM03676.1 - 0.011 15.4 0.4 0.045 13.4 0.1 2.1 2 0 0 2 2 2 0 F-box-like FYRN PF05964.9 CCM03678.1 - 6.1e-15 54.4 0.2 1.1e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 CCM03678.1 - 8.3e-15 54.3 0.0 1.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus YTH PF04146.10 CCM03681.1 - 7.5e-51 171.4 0.0 1.7e-50 170.2 0.0 1.6 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 CCM03681.1 - 0.00057 19.4 0.0 0.21 11.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM03681.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03681.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CCM03683.1 - 1.2e-25 90.1 1.3 3.8e-12 45.9 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03683.1 - 2.4e-16 59.5 0.0 5.7e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CCM03683.1 - 2.9e-07 30.4 0.0 0.039 13.6 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM03683.1 - 1.2e-06 28.2 0.0 0.062 12.8 0.0 2.7 2 0 0 2 2 2 2 Choline/ethanolamine kinase Kdo PF06293.9 CCM03683.1 - 3.3e-06 26.3 0.1 0.063 12.3 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM03683.1 - 1.9e-05 24.1 0.0 0.19 11.0 0.0 2.4 2 0 0 2 2 2 2 RIO1 family DUF1217 PF06748.7 CCM03683.1 - 0.0067 16.5 0.0 5.6 7.0 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1217) Ribosomal_L4 PF00573.17 CCM03683.1 - 2.8 7.2 6.2 0.43 9.9 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L4/L1 family MutS_V PF00488.16 CCM03684.1 - 5.4e-73 245.2 0.0 1e-72 244.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCM03684.1 - 5.9e-37 127.4 0.2 1.4e-36 126.2 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCM03684.1 - 3.2e-22 78.7 0.0 6.9e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CCM03684.1 - 2e-10 40.8 0.0 7.4e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CCM03684.1 - 1.4e-08 34.8 0.3 3.5e-08 33.5 0.2 1.7 1 0 0 1 1 1 1 MutS family domain IV BORA_N PF15280.1 CCM03684.1 - 0.00058 19.2 2.3 0.0011 18.4 1.6 1.3 1 0 0 1 1 1 1 Protein aurora borealis N-terminus Spore_III_AB PF09548.5 CCM03685.1 - 0.072 12.8 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) CAP_N PF01213.14 CCM03686.1 - 4.3e-79 266.0 18.5 1.5e-78 264.2 12.8 2.5 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CCM03686.1 - 5.2e-58 194.8 2.3 6.8e-58 194.5 1.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CCM03686.1 - 0.026 13.9 3.5 0.062 12.6 2.4 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor C LETM1 PF07766.8 CCM03687.1 - 5.8e-98 327.1 0.2 5.8e-98 327.1 0.1 2.2 2 1 0 2 2 2 1 LETM1-like protein SAP PF02037.22 CCM03687.1 - 0.00018 20.9 1.6 0.015 14.7 0.0 3.6 4 0 0 4 4 4 1 SAP domain EF-hand_1 PF00036.27 CCM03687.1 - 0.0012 17.9 0.1 0.24 10.8 0.0 3.7 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.1 CCM03687.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CCM03687.1 - 0.031 14.1 0.1 13 6.0 0.0 4.0 3 0 0 3 3 3 0 EF-hand domain MCPVI PF02993.9 CCM03687.1 - 0.31 11.1 10.5 0.28 11.3 0.6 2.3 2 0 0 2 2 2 0 Minor capsid protein VI RRN7 PF11781.3 CCM03689.1 - 0.00072 18.9 1.9 0.0016 17.8 1.3 1.6 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 CCM03689.1 - 0.016 14.4 1.8 0.038 13.3 1.2 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding TFIIB PF00382.14 CCM03689.1 - 0.028 14.2 0.1 0.083 12.7 0.1 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat zf-ribbon_3 PF13248.1 CCM03689.1 - 0.16 11.2 0.3 0.29 10.3 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RF-1 PF00472.15 CCM03690.1 - 8.8e-24 83.5 3.5 8.8e-24 83.5 2.4 1.8 2 0 0 2 2 2 1 RF-1 domain Amidohydro_1 PF01979.15 CCM03690.1 - 7.7e-15 55.3 0.0 7.2e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 CCM03690.1 - 1.2e-12 48.4 0.3 1.7e-11 44.6 0.2 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 CCM03690.1 - 2.9e-12 46.2 0.0 7e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CCM03690.1 - 3.9e-06 26.3 0.2 0.0075 15.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.7 CCM03690.1 - 9.2e-05 22.0 3.1 0.018 14.6 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DNA_pol_phi PF04931.8 CCM03691.1 - 1.7e-63 214.6 16.5 4.9e-53 180.0 3.3 2.7 3 0 0 3 3 3 2 DNA polymerase phi Nt_Gln_amidase PF09764.4 CCM03693.1 - 3.3e-26 91.7 1.8 5.2e-24 84.5 1.2 2.8 1 1 0 1 1 1 1 N-terminal glutamine amidase Transferase PF02458.10 CCM03694.1 - 1.3e-33 116.1 0.0 4e-13 48.6 0.0 3.1 3 0 0 3 3 3 3 Transferase family UQ_con PF00179.21 CCM03697.1 - 1.4e-35 121.8 0.2 5.1e-18 64.8 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.8 CCM03697.1 - 0.011 15.4 1.2 0.16 11.6 0.1 2.1 1 1 0 2 2 2 0 UEV domain Prok-E2_B PF14461.1 CCM03697.1 - 0.043 13.5 0.1 7 6.4 0.0 2.2 1 1 1 2 2 2 0 Prokaryotic E2 family B SPRY PF00622.23 CCM03698.1 - 1.7e-09 37.8 0.0 1.4e-08 34.8 0.0 2.4 3 0 0 3 3 3 1 SPRY domain PhoD PF09423.5 CCM03699.1 - 1e-06 27.6 0.0 0.00081 18.0 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase MutS_V PF00488.16 CCM03700.1 - 2.4e-55 187.5 0.0 5.3e-53 179.8 0.0 2.6 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.13 CCM03700.1 - 5.6e-31 107.9 3.0 5.6e-31 107.9 2.1 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 CCM03700.1 - 1.5e-07 31.4 0.1 1.1e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 CCM03700.1 - 7e-06 26.1 0.3 2.5e-05 24.3 0.2 2.1 1 1 0 1 1 1 1 MutS domain II DAO PF01266.19 CCM03701.1 - 3.7e-35 121.4 1.9 5.6e-35 120.8 1.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCM03701.1 - 0.0018 17.2 0.2 0.0073 15.1 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCM03701.1 - 0.0041 17.1 0.2 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCM03701.1 - 0.0051 16.8 0.1 0.43 10.6 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCM03701.1 - 0.0075 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM03701.1 - 0.022 13.8 0.1 0.046 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 CCM03701.1 - 0.098 12.4 1.0 0.79 9.4 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding YmzC PF14157.1 CCM03701.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 YmzC-like protein Amidase PF01425.16 CCM03702.1 - 1.6e-18 66.8 0.0 7.1e-17 61.3 0.0 2.0 1 1 0 1 1 1 1 Amidase Amidase PF01425.16 CCM03703.1 - 1.5e-28 99.8 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF4587 PF15248.1 CCM03704.1 - 8 7.1 13.5 0.49 11.0 2.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4587) RNA_pol_Rpb1_5 PF04998.12 CCM03706.1 - 3.3e-104 348.0 0.0 5e-104 347.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCM03706.1 - 1.9e-68 229.6 0.0 3.6e-68 228.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CCM03706.1 - 1.5e-66 223.6 0.0 3.3e-66 222.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_1 PF04997.7 CCM03706.1 - 3.1e-62 210.8 0.0 4.3e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 CCM03706.1 - 9.8e-48 161.8 0.0 4.7e-47 159.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CCM03706.1 - 3e-44 150.0 1.3 4.1e-44 149.5 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CCM03706.1 - 2.5e-34 117.2 0.0 5.2e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 CCM03706.1 - 0.32 11.2 213.4 0.056 13.5 3.1 14.0 10 2 5 15 15 15 0 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_1 PF04997.7 CCM03707.1 - 1.1e-35 123.5 0.0 1.3e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 VHS PF00790.14 CCM03708.1 - 2.7e-44 150.2 0.0 3.2e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 VHS domain UIM PF02809.15 CCM03709.1 - 0.0061 16.0 14.6 0.041 13.4 1.9 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif Vps35 PF03635.12 CCM03710.1 - 0 1057.8 0.4 0 1057.6 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF3580 PF12117.3 CCM03710.1 - 0.049 13.5 2.6 0.11 12.4 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Ribonuc_L-PSP PF01042.16 CCM03710.1 - 0.084 12.6 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP DUF202 PF02656.10 CCM03711.1 - 3.6e-19 68.7 0.2 2.7e-18 65.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Pro_dh PF01619.13 CCM03712.1 - 6.8e-39 133.6 0.0 5.1e-19 68.4 0.1 3.2 2 2 0 2 2 2 2 Proline dehydrogenase AP_endonuc_2 PF01261.19 CCM03712.1 - 0.0094 15.2 0.0 0.051 12.8 0.0 2.1 3 0 0 3 3 3 1 Xylose isomerase-like TIM barrel BCIP PF13862.1 CCM03713.1 - 4.3e-59 199.3 0.0 5.2e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein TIP120 PF08623.5 CCM03714.1 - 8.7e-52 175.1 2.7 1.3e-50 171.3 0.1 3.6 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 CCM03714.1 - 7.1e-20 71.0 11.2 4.4e-05 23.6 0.1 8.3 7 1 2 9 9 7 5 HEAT repeats HEAT_EZ PF13513.1 CCM03714.1 - 1.1e-15 57.5 18.4 0.029 14.8 0.0 11.9 10 1 3 13 13 13 3 HEAT-like repeat HEAT PF02985.17 CCM03714.1 - 3.7e-15 54.5 20.6 0.004 17.1 0.0 13.0 14 0 0 14 14 13 3 HEAT repeat Adaptin_N PF01602.15 CCM03714.1 - 1.6e-13 49.8 4.6 0.0062 14.9 0.0 6.1 5 2 1 6 6 6 4 Adaptin N terminal region Cnd1 PF12717.2 CCM03714.1 - 1.1e-12 48.1 3.8 0.02 14.7 0.1 7.0 5 3 2 8 8 7 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 CCM03714.1 - 9.8e-10 38.1 5.9 0.0007 19.0 0.1 5.3 5 1 0 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 CCM03714.1 - 3.1e-06 27.4 2.8 4.2 7.8 0.0 6.4 7 2 2 9 9 7 2 Vacuolar 14 Fab1-binding region UME PF08064.8 CCM03714.1 - 0.00012 22.0 3.3 3.1 7.7 0.0 4.3 3 1 0 3 3 3 2 UME (NUC010) domain ParcG PF10274.4 CCM03714.1 - 0.0015 18.4 1.3 0.34 10.7 0.0 4.7 6 0 0 6 6 5 1 Parkin co-regulated protein CAS_CSE1 PF03378.10 CCM03714.1 - 0.0028 16.0 0.1 0.1 10.8 0.0 3.4 4 0 0 4 4 4 1 CAS/CSE protein, C-terminus DUF3385 PF11865.3 CCM03714.1 - 0.022 14.6 3.2 5.1 6.9 0.0 5.0 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) DUF1546 PF07571.8 CCM03714.1 - 0.075 13.1 0.9 11 6.1 0.0 4.4 4 1 1 5 5 4 0 Protein of unknown function (DUF1546) Arm PF00514.18 CCM03714.1 - 0.54 10.1 7.1 26 4.8 0.0 6.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.3 CCM03714.1 - 0.69 9.8 3.3 3.7 7.4 0.1 4.0 5 0 0 5 5 5 0 V-ATPase subunit H DUF2457 PF10446.4 CCM03714.1 - 5 5.7 7.5 8.1 5.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AAA PF00004.24 CCM03715.1 - 2.7e-41 140.8 0.0 4.4e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CCM03715.1 - 5e-25 87.1 0.0 3.2e-24 84.6 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CCM03715.1 - 4.6e-21 74.4 6.3 4.6e-21 74.4 4.4 2.4 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 CCM03715.1 - 2.4e-06 27.7 1.7 0.0006 19.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCM03715.1 - 6.5e-06 25.9 0.1 3.6e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CCM03715.1 - 1.5e-05 24.2 0.0 3.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCM03715.1 - 1.8e-05 25.5 0.0 6.2e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCM03715.1 - 2.1e-05 24.0 0.0 5.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 CCM03715.1 - 2.1e-05 24.5 0.1 0.00044 20.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CCM03715.1 - 5.3e-05 23.1 0.1 0.00014 21.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CCM03715.1 - 9.3e-05 21.9 0.4 0.14 11.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 CCM03715.1 - 0.00016 20.6 0.0 0.00099 18.0 0.0 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CCM03715.1 - 0.00026 20.9 0.0 0.00065 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCM03715.1 - 0.0013 18.6 0.1 0.007 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CCM03715.1 - 0.0016 17.2 0.1 0.0035 16.1 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 CCM03715.1 - 0.0027 17.8 0.0 0.008 16.3 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 CCM03715.1 - 0.0051 15.9 0.1 0.092 11.8 0.1 2.4 1 1 0 1 1 1 1 Zeta toxin KaiC PF06745.8 CCM03715.1 - 0.0054 15.8 0.1 1.5 7.9 0.0 2.3 1 1 1 2 2 2 1 KaiC AAA_24 PF13479.1 CCM03715.1 - 0.0099 15.4 0.2 0.044 13.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCM03715.1 - 0.012 15.9 1.0 0.02 15.2 0.0 2.0 3 0 0 3 3 1 0 AAA domain NACHT PF05729.7 CCM03715.1 - 0.015 14.9 0.0 0.4 10.3 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 CCM03715.1 - 0.015 15.1 0.1 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CCM03715.1 - 0.016 14.4 1.6 0.064 12.4 0.1 2.4 2 1 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 CCM03715.1 - 0.023 14.4 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 CCM03715.1 - 0.024 14.3 2.8 0.48 10.0 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 CCM03715.1 - 0.027 14.5 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 CCM03715.1 - 0.035 13.2 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 CCM03715.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 CCM03715.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.23 CCM03715.1 - 0.092 12.3 1.3 26 4.6 1.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCM03715.1 - 1.6 8.8 6.1 9.8 6.3 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Pkinase PF00069.20 CCM03716.1 - 4.1e-62 209.6 0.0 5.7e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03716.1 - 5.4e-23 81.3 0.0 7.2e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM03716.1 - 8.4e-06 24.9 0.0 1.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like GSK-3_bind PF05350.7 CCM03716.1 - 0.02 14.3 4.0 0.042 13.2 2.8 1.6 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding FAD_binding_4 PF01565.18 CCM03716.1 - 0.1 12.0 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Ribosomal_L19e PF01280.15 CCM03717.1 - 8.1e-62 207.3 12.3 8.1e-62 207.3 8.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 CCM03717.1 - 0.01 15.2 0.0 0.036 13.4 0.0 1.9 1 0 0 1 1 1 0 S4 domain DUF3049 PF11250.3 CCM03717.1 - 0.086 12.6 2.5 0.093 12.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3049) DUF349 PF03993.7 CCM03717.1 - 0.77 9.9 11.3 19 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) MOZ_SAS PF01853.13 CCM03718.1 - 3.5e-64 215.5 0.2 7.7e-64 214.4 0.1 1.6 2 0 0 2 2 2 1 MOZ/SAS family Tudor-knot PF11717.3 CCM03718.1 - 2.8e-07 30.1 0.4 6.9e-07 28.8 0.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 CCM03718.1 - 0.073 13.1 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Pkinase PF00069.20 CCM03719.1 - 3.2e-32 111.7 0.0 4.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03719.1 - 3.4e-14 52.5 0.0 5.4e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM03719.1 - 0.0076 15.2 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCM03719.1 - 0.067 12.9 6.1 0.62 9.7 0.6 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family F-box-like PF12937.2 CCM03720.1 - 6.1e-08 32.2 0.3 1.1e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM03720.1 - 6.3e-06 25.6 0.1 1e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 CCM03721.1 - 2.3e-12 46.6 0.0 3.1e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03721.1 - 2.4e-07 30.0 0.0 3.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM03721.1 - 0.0009 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM03721.1 - 0.0088 15.6 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CCM03721.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM03721.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Guanylate_kin PF00625.16 CCM03721.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase adh_short PF00106.20 CCM03722.1 - 5.4e-10 39.4 0.3 5.8e-09 36.0 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM03722.1 - 0.046 13.3 0.2 0.13 11.8 0.0 1.8 1 1 1 2 2 2 0 KR domain C1q PF00386.16 CCM03722.1 - 0.093 12.7 0.0 0.54 10.2 0.0 1.9 1 1 1 2 2 2 0 C1q domain p450 PF00067.17 CCM03723.1 - 1.7e-64 218.0 0.0 3.1e-63 213.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.1 CCM03724.1 - 1.8e-23 83.2 0.0 5.6e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM03724.1 - 1.1e-20 73.6 0.0 2e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaI_N PF07319.6 CCM03724.1 - 0.15 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus GPI-anchored PF10342.4 CCM03725.1 - 0.00056 20.3 0.4 0.00073 19.9 0.3 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA PF00004.24 CCM03726.1 - 1e-38 132.5 0.0 1.8e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCM03726.1 - 1.8e-07 30.4 0.0 3.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCM03726.1 - 6e-06 27.0 0.0 2.4e-05 25.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CCM03726.1 - 6.5e-06 26.3 0.2 0.00095 19.3 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.9 CCM03726.1 - 7e-06 26.0 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CCM03726.1 - 8.6e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM03726.1 - 2.2e-05 24.5 0.2 0.0021 18.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CCM03726.1 - 6.7e-05 22.6 0.4 0.00098 18.8 0.3 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCM03726.1 - 7.2e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCM03726.1 - 0.00013 21.1 0.1 0.00031 19.9 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin IstB_IS21 PF01695.12 CCM03726.1 - 0.0003 20.2 0.0 0.00055 19.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 CCM03726.1 - 0.00037 20.4 0.2 0.0015 18.5 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 CCM03726.1 - 0.00046 20.4 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCM03726.1 - 0.00067 18.8 0.3 0.0015 17.7 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CCM03726.1 - 0.00074 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 CCM03726.1 - 0.00079 18.8 0.5 0.07 12.5 0.2 2.5 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 CCM03726.1 - 0.0016 17.2 0.0 0.0023 16.6 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 CCM03726.1 - 0.0017 17.1 0.0 0.0034 16.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 CCM03726.1 - 0.0023 18.1 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Bac_DnaA PF00308.13 CCM03726.1 - 0.0046 16.6 0.0 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.7 CCM03726.1 - 0.0074 15.9 0.1 0.024 14.3 0.0 1.9 1 1 1 2 2 2 1 NACHT domain ABC_tran PF00005.22 CCM03726.1 - 0.0092 16.2 0.0 0.019 15.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 CCM03726.1 - 0.014 14.8 0.6 0.37 10.1 0.4 2.7 1 1 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 CCM03726.1 - 0.015 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CCM03726.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 CCM03726.1 - 0.026 14.3 0.0 0.071 12.9 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase AAA_21 PF13304.1 CCM03726.1 - 0.028 14.3 0.1 1.2 9.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCM03726.1 - 0.036 13.7 0.0 0.44 10.1 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase tRNA_lig_kinase PF08303.6 CCM03726.1 - 0.04 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain ATP-synt_ab PF00006.20 CCM03726.1 - 0.044 13.2 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 CCM03726.1 - 0.045 12.8 0.1 2.1 7.4 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_19 PF13245.1 CCM03726.1 - 0.066 12.9 0.6 0.17 11.6 0.1 2.0 2 1 0 2 2 1 0 Part of AAA domain UPF0079 PF02367.12 CCM03726.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CCM03726.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CCM03726.1 - 0.075 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 CCM03726.1 - 0.084 12.3 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 CCM03726.1 - 0.094 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CCM03726.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PduV-EutP PF10662.4 CCM03726.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Guanylate_kin PF00625.16 CCM03726.1 - 0.14 11.6 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase Trehalase PF01204.13 CCM03727.1 - 4.5e-114 381.9 5.0 8.9e-102 341.3 0.1 2.1 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 CCM03727.1 - 0.0016 17.2 0.1 0.02 13.6 0.0 2.1 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase RRM_1 PF00076.17 CCM03728.1 - 3.1e-08 33.1 0.0 8.9e-08 31.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 CCM03728.1 - 2.3e-06 27.6 0.2 5.2e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_6 PF14259.1 CCM03728.1 - 0.00076 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM03728.1 - 0.034 13.9 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sad1_UNC PF07738.8 CCM03729.1 - 5.6e-31 107.1 0.0 9.9e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ATP-synt_C PF00137.16 CCM03730.1 - 2.5e-31 107.3 31.7 3.5e-18 65.2 9.7 2.3 2 1 0 2 2 2 2 ATP synthase subunit C Pyr_redox_2 PF07992.9 CCM03731.1 - 6.4e-29 101.2 0.0 8.2e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM03731.1 - 3e-16 59.5 0.3 2.6e-13 50.1 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM03731.1 - 5e-07 29.9 0.1 0.0024 17.9 0.0 2.4 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM03731.1 - 1.6e-06 27.3 0.1 4.8e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 CCM03731.1 - 4.2e-06 25.8 0.0 0.00021 20.3 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CCM03731.1 - 1.2e-05 24.4 1.9 0.0042 16.0 0.1 3.4 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCM03731.1 - 2.9e-05 23.0 1.0 0.0021 16.9 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CCM03731.1 - 6.7e-05 22.8 0.3 0.0019 18.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 CCM03731.1 - 0.00023 21.2 0.1 0.39 10.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CCM03731.1 - 0.00076 19.7 0.1 0.044 14.0 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 CCM03731.1 - 0.0015 17.7 0.5 0.03 13.4 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCM03731.1 - 0.003 16.6 0.2 0.051 12.6 0.0 2.4 2 1 1 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 CCM03731.1 - 0.0035 16.3 0.1 0.53 9.1 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 CCM03731.1 - 0.0048 15.4 0.7 0.039 12.4 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.9 CCM03731.1 - 0.01 14.4 0.8 0.053 12.1 0.2 2.3 2 1 1 3 3 3 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 CCM03731.1 - 0.051 13.3 0.3 2 8.1 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 CCM03731.1 - 0.063 13.7 0.0 6 7.3 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.1 CCM03731.1 - 0.084 12.6 0.1 8.5 6.1 0.1 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.11 CCM03731.1 - 0.12 11.8 0.4 19 4.6 0.1 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Tetraspannin PF00335.15 CCM03732.1 - 1.6e-14 53.7 7.5 2.4e-14 53.1 5.2 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4227 PF14004.1 CCM03732.1 - 0.93 9.3 2.8 1.8 8.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) 5TM-5TMR_LYT PF07694.7 CCM03732.1 - 1.4 8.2 12.3 14 4.9 0.1 2.6 2 1 1 3 3 3 0 5TMR of 5TMR-LYT RicinB_lectin_2 PF14200.1 CCM03734.1 - 4.9e-07 30.0 1.7 1.2e-05 25.6 0.2 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CCM03734.1 - 0.017 15.1 0.3 0.65 10.0 0.0 2.2 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Glycos_transf_1 PF00534.15 CCM03735.1 - 3.6e-23 81.8 0.0 6e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCM03735.1 - 1.5e-08 34.8 0.0 2.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 FTR1 PF03239.9 CCM03735.1 - 0.13 11.1 0.2 1.5 7.7 0.0 2.3 2 1 1 3 3 3 0 Iron permease FTR1 family FMN_dh PF01070.13 CCM03736.1 - 2.3e-114 381.9 0.0 3.2e-114 381.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 CCM03736.1 - 5.8e-05 22.1 0.0 9.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 CCM03736.1 - 0.00018 20.7 0.0 0.32 10.0 0.0 3.0 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 CCM03736.1 - 0.00038 19.4 0.2 0.0021 16.9 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF814 PF05670.8 CCM03737.1 - 6.1e-17 61.2 0.1 2e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF814) NOT2_3_5 PF04153.13 CCM03738.1 - 5e-32 110.6 0.4 5e-32 110.6 0.3 2.3 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family RNA_pol_Rpb4 PF03874.11 CCM03739.1 - 1.5e-22 79.7 2.2 2.1e-22 79.3 1.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DED PF01335.16 CCM03739.1 - 0.043 13.9 0.1 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Death effector domain DUF2217 PF10265.4 CCM03739.1 - 0.12 11.1 0.4 0.14 10.9 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) ENTH PF01417.15 CCM03741.1 - 8.8e-42 141.9 0.1 1.5e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CCM03741.1 - 0.069 11.8 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 ANTH domain Glyco_hydro_20 PF00728.17 CCM03742.1 - 7.9e-81 271.9 0.1 9.6e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CCM03742.1 - 8.9e-13 49.0 0.0 1.6e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CCM03742.1 - 6e-06 26.8 0.1 2.6e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 CCT_2 PF09425.5 CCM03743.1 - 0.048 13.1 0.6 0.13 11.7 0.4 1.8 1 0 0 1 1 1 0 Divergent CCT motif Lgl_C PF08596.5 CCM03744.1 - 5.6e-17 61.2 0.0 8.5e-12 44.2 0.0 2.4 2 0 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CCM03744.1 - 2.6e-07 30.2 0.7 0.00014 21.5 0.1 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF287 PF03384.9 CCM03744.1 - 0.024 14.7 0.1 0.051 13.7 0.1 1.4 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 Synaptobrevin PF00957.16 CCM03745.1 - 0.013 15.0 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Synaptobrevin SnoaL_2 PF12680.2 CCM03746.1 - 0.0011 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.4 CCM03746.1 - 0.032 14.1 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) DUF1296 PF06972.6 CCM03746.1 - 0.086 12.8 0.2 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) Asp PF00026.18 CCM03747.1 - 1.3e-45 156.0 19.0 4.1e-45 154.4 13.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCM03747.1 - 4.3e-07 30.3 7.3 1.2e-05 25.7 1.9 3.3 3 0 0 3 3 3 1 Aspartyl protease TAXi_N PF14543.1 CCM03747.1 - 0.00011 22.2 6.4 0.0066 16.4 2.7 3.7 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 CCM03747.1 - 0.063 13.1 0.6 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 CCM03747.1 - 0.11 12.4 1.0 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-RING_2 PF13639.1 CCM03748.1 - 1.8e-13 50.0 4.6 1.8e-13 50.0 3.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CCM03748.1 - 1.8e-11 43.9 0.7 1.8e-11 43.9 0.5 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CCM03748.1 - 3.6e-07 29.8 3.0 3.6e-07 29.8 2.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCM03748.1 - 8.4e-07 28.5 9.8 9.2e-07 28.4 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCM03748.1 - 1e-06 28.6 1.7 1e-06 28.6 1.2 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCM03748.1 - 1.8e-06 27.5 4.5 1.8e-06 27.5 3.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCM03748.1 - 2.9e-06 27.0 0.3 5.8e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 CCM03748.1 - 7.8e-06 25.7 4.8 9e-06 25.5 1.5 2.3 2 0 0 2 2 2 1 zinc-finger FANCL_C PF11793.3 CCM03748.1 - 0.015 15.2 4.2 0.084 12.8 2.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CCM03748.1 - 0.044 13.4 3.2 0.12 12.1 0.9 2.4 1 1 1 2 2 2 0 RING-type zinc-finger HypA PF01155.14 CCM03748.1 - 0.14 11.8 2.9 8.3 6.1 0.2 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE_2 PF02318.11 CCM03748.1 - 0.72 9.7 3.6 2 8.3 0.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger PHD PF00628.24 CCM03748.1 - 1.7 8.3 15.5 0.52 10.0 2.8 2.6 3 0 0 3 3 3 0 PHD-finger RINGv PF12906.2 CCM03748.1 - 4 7.5 7.9 0.64 10.1 1.2 2.4 2 1 0 2 2 2 0 RING-variant domain Prok-RING_1 PF14446.1 CCM03748.1 - 6.2 6.6 11.7 1.9 8.2 3.8 2.9 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 DZR PF12773.2 CCM03748.1 - 8.4 6.3 9.7 2.9 7.7 0.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon Aldedh PF00171.17 CCM03749.1 - 4e-117 391.3 0.0 5e-117 391.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribonuclease_T2 PF00445.13 CCM03749.1 - 1.3e-38 132.5 2.1 6.8e-38 130.1 1.8 1.9 2 0 0 2 2 2 1 Ribonuclease T2 family LuxC PF05893.9 CCM03749.1 - 0.0076 15.0 1.0 0.11 11.2 0.7 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF89 PF01937.14 CCM03750.1 - 1.1e-110 369.7 0.1 1.5e-110 369.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 WD40 PF00400.27 CCM03751.1 - 1.5e-75 246.6 19.1 8.5e-09 34.9 0.1 11.6 11 0 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 CCM03751.1 - 4.2e-36 123.7 0.0 6.7e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CCM03751.1 - 0.00024 19.3 4.4 3.4 5.7 0.6 5.0 3 2 0 3 3 3 3 Nucleoporin Nup120/160 Met_synt_B12 PF02965.12 CCM03751.1 - 0.019 14.1 0.1 0.06 12.5 0.0 1.7 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain VID27 PF08553.5 CCM03751.1 - 0.11 10.7 0.0 0.17 10.0 0.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Fork_head PF00250.13 CCM03752.1 - 2.9e-17 62.4 0.1 3.3e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Fork head domain Bradykinin PF06753.7 CCM03752.1 - 0.048 13.1 0.4 0.048 13.1 0.2 3.6 3 0 0 3 3 3 0 Bradykinin NIPSNAP PF07978.8 CCM03753.1 - 1.5e-30 105.1 0.7 2.9e-24 85.0 0.1 2.2 2 0 0 2 2 2 2 NIPSNAP F5_F8_type_C PF00754.20 CCM03754.1 - 0.064 13.0 0.0 0.28 11.0 0.0 2.0 2 1 0 2 2 2 0 F5/8 type C domain Mob_synth_C PF06463.8 CCM03755.1 - 3.6e-37 126.9 0.0 8.2e-37 125.7 0.0 1.6 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 CCM03755.1 - 2.4e-26 92.8 0.1 2.8e-25 89.4 0.0 2.3 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.1 CCM03755.1 - 4.7e-07 30.0 0.0 1.7e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 CCM03755.1 - 0.00012 22.0 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain MoaC PF01967.16 CCM03756.1 - 1.5e-40 138.0 1.8 1.5e-18 66.7 0.0 3.1 2 1 0 2 2 2 2 MoaC family Acetyltransf_10 PF13673.1 CCM03757.1 - 4.8e-09 36.3 0.0 9.8e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCM03757.1 - 3e-07 30.0 0.0 5.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CCM03757.1 - 5.2e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM03757.1 - 1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CCM03757.1 - 0.0032 17.3 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PAT1 PF09770.4 CCM03758.1 - 5.5 5.0 42.1 6.8 4.7 29.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 polyprenyl_synt PF00348.12 CCM03760.1 - 6.9e-47 159.4 0.0 3.8e-43 147.2 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HTH_17 PF12728.2 CCM03761.1 - 0.055 13.7 0.1 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PAT1 PF09770.4 CCM03762.1 - 0.018 13.3 4.0 0.027 12.7 2.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Moulting_cycle PF04870.11 CCM03762.1 - 4.8 6.1 6.6 7.3 5.5 4.6 1.2 1 0 0 1 1 1 0 Moulting cycle DUF837 PF05769.6 CCM03763.1 - 1.3e-08 34.5 9.9 7.4e-06 25.6 3.2 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF837) DUF2414 PF10309.4 CCM03764.1 - 5.8e-08 32.3 0.0 1.7e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 CCM03764.1 - 4.1e-05 23.4 0.0 7.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain WD40 PF00400.27 CCM03768.1 - 1.3e-47 157.9 19.9 3.5e-08 33.0 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Tropomyosin PF00261.15 CCM03768.1 - 6.7e-05 22.0 45.7 6.7e-05 22.0 31.7 6.1 1 1 5 6 6 6 2 Tropomyosin ATG16 PF08614.6 CCM03768.1 - 0.0052 16.6 11.4 0.0052 16.6 7.9 6.6 1 1 7 8 8 8 2 Autophagy protein 16 (ATG16) eIF2A PF08662.6 CCM03768.1 - 0.024 14.3 0.0 0.89 9.2 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Reo_sigmaC PF04582.7 CCM03768.1 - 0.11 11.6 51.5 0.27 10.3 0.4 6.4 1 1 2 5 5 5 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 CCM03768.1 - 0.33 8.6 111.3 0.035 11.8 14.1 4.0 1 1 1 3 3 3 0 Myosin tail dsrm PF00035.20 CCM03769.1 - 3.7e-11 43.4 0.0 4.2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.20 CCM03770.1 - 2.5e-08 34.3 0.0 2.7e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif UCH PF00443.24 CCM03771.1 - 3e-28 98.6 0.0 4.1e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCM03771.1 - 3.5e-11 43.0 0.1 6.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein PCI PF01399.22 CCM03772.1 - 4.8e-21 75.0 0.7 1.3e-20 73.7 0.5 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CCM03772.1 - 1.7e-11 44.0 0.3 4.4e-11 42.7 0.2 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 CCM03772.1 - 0.027 14.1 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator MRP-L28 PF09812.4 CCM03773.1 - 0.0003 20.6 0.1 0.021 14.6 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 Ribosomal_L1 PF00687.16 CCM03774.1 - 1.6e-19 70.1 0.1 2.2e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Rsm22 PF09243.5 CCM03775.1 - 3.1e-44 151.0 0.0 1.9e-29 102.5 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Bromodomain PF00439.20 CCM03776.1 - 4.8e-59 196.2 0.0 3.1e-19 68.6 0.0 3.8 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 CCM03776.1 - 3.9e-09 36.1 0.1 1.6e-05 24.2 0.0 3.2 2 1 0 2 2 2 2 Peptidase family M1 HEAT_2 PF13646.1 CCM03776.1 - 0.021 15.0 3.4 2.2 8.6 0.0 3.7 4 0 0 4 4 4 0 HEAT repeats UCH PF00443.24 CCM03777.1 - 5.2e-06 25.7 0.0 1.1e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 CCM03777.1 - 0.0014 18.1 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 CCM03777.1 - 0.03 14.1 0.0 0.11 12.3 0.0 2.0 1 0 0 1 1 1 0 UBA/TS-N domain Peptidase_M16_C PF05193.16 CCM03777.1 - 0.079 12.6 0.0 0.25 11.0 0.0 1.9 1 0 0 1 1 1 0 Peptidase M16 inactive domain UIM PF02809.15 CCM03777.1 - 0.15 11.6 0.1 0.15 11.6 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin interaction motif LTV PF04180.9 CCM03778.1 - 5.4e-62 210.6 23.3 2.4e-58 198.6 5.8 4.2 2 1 2 4 4 4 3 Low temperature viability protein PIP5K PF01504.13 CCM03779.1 - 2.2e-64 217.0 0.1 3.8e-64 216.2 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CCM03779.1 - 2.7e-25 88.9 0.0 4.1e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CCM03779.1 - 7e-17 61.0 11.5 7e-17 61.0 8.0 2.0 2 0 0 2 2 2 1 FYVE zinc finger DUF3410 PF11890.3 CCM03779.1 - 0.003 17.1 3.6 0.12 12.0 0.6 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3410) Med11 PF10280.4 CCM03780.1 - 3.3e-05 23.8 0.0 4.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein TBCA PF02970.11 CCM03781.1 - 5.8e-17 61.5 6.6 1.5e-16 60.2 4.4 1.7 1 1 0 1 1 1 1 Tubulin binding cofactor A Ribosomal_L35p PF01632.14 CCM03781.1 - 0.045 13.6 1.1 0.082 12.8 0.8 1.5 1 0 0 1 1 1 0 Ribosomal protein L35 HSA PF07529.8 CCM03781.1 - 0.1 12.3 4.9 4 7.3 1.4 2.2 2 0 0 2 2 2 0 HSA DUF925 PF06042.6 CCM03781.1 - 0.42 10.1 2.8 0.97 8.9 0.3 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF925) ATP-synt_B PF00430.13 CCM03781.1 - 4.2 7.1 7.8 0.63 9.8 1.1 2.0 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) HLH PF00010.21 CCM03782.1 - 1.3e-08 34.3 2.8 1.3e-08 34.3 2.0 2.7 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.14 CCM03782.1 - 0.5 10.8 5.0 3.3 8.1 1.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein HLH PF00010.21 CCM03785.1 - 2.8e-11 42.9 1.6 8.5e-11 41.3 0.6 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HlyD PF00529.15 CCM03785.1 - 0.013 14.8 1.6 0.018 14.3 1.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF2205 PF10224.4 CCM03785.1 - 0.057 12.9 0.4 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Ribosomal_L44 PF00935.14 CCM03785.1 - 0.11 12.5 0.0 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L44 IncA PF04156.9 CCM03785.1 - 0.36 10.4 2.7 0.57 9.7 1.9 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 CCM03785.1 - 4.6 6.7 5.4 4.6 6.7 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator ATG27 PF09451.5 CCM03786.1 - 9.5e-06 25.0 0.2 3.4e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 CCM03786.1 - 3.9e-05 22.8 0.0 4.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 CCM03786.1 - 7.7e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat Complex1_49kDa PF00346.14 CCM03787.1 - 7.8e-116 385.8 0.0 3.5e-115 383.6 0.0 1.8 1 1 1 2 2 2 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 CCM03787.1 - 0.059 12.1 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase NIF3 PF01784.13 CCM03788.1 - 4.6e-63 213.0 0.0 5.5e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) NTP_transf_3 PF12804.2 CCM03788.1 - 0.024 14.7 0.1 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain Glutaredoxin PF00462.19 CCM03789.1 - 1.6e-17 63.1 0.0 2.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CCM03789.1 - 0.00041 20.1 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 CCM03789.1 - 0.00042 20.4 0.3 0.0012 19.0 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 CCM03789.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.1 CCM03789.1 - 0.021 14.8 0.1 3.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin DUF836 PF05768.9 CCM03789.1 - 0.025 14.8 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF953 PF06110.6 CCM03789.1 - 0.076 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Adaptin_N PF01602.15 CCM03790.1 - 3.4e-97 325.9 5.1 4.8e-97 325.4 3.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CCM03790.1 - 1.1e-65 219.1 0.0 2.6e-65 217.9 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CCM03790.1 - 1.8e-57 192.9 0.1 7.1e-57 191.0 0.0 2.1 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CCM03790.1 - 3.4e-11 43.2 0.1 0.0009 19.4 0.0 4.9 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.17 CCM03790.1 - 2.5e-05 23.9 0.2 0.054 13.5 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 CCM03790.1 - 0.00016 21.5 4.6 0.35 10.6 0.0 4.3 1 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Gemini_V1 PF01524.12 CCM03790.1 - 0.0072 16.2 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 1 Geminivirus V1 protein ParcG PF10274.4 CCM03790.1 - 0.013 15.4 2.8 0.83 9.5 0.0 3.1 3 1 0 3 3 3 0 Parkin co-regulated protein HEAT_EZ PF13513.1 CCM03790.1 - 0.16 12.5 0.7 21 5.7 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat Transp_cyt_pur PF02133.10 CCM03791.1 - 1.4e-22 79.9 29.2 1.8e-22 79.4 20.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YqhR PF11085.3 CCM03791.1 - 0.83 9.1 8.2 2.6 7.5 5.7 1.8 1 0 0 1 1 1 0 Conserved membrane protein YqhR COX2-transmemb PF09125.5 CCM03791.1 - 5.1 6.7 7.7 1.3 8.6 0.7 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane Kelch_4 PF13418.1 CCM03792.1 - 1.8e-17 62.7 3.5 3.5e-09 36.2 0.0 4.8 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CCM03792.1 - 3.5e-14 52.5 12.3 0.0013 18.8 0.2 7.1 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CCM03792.1 - 6.1e-10 38.8 6.5 0.0011 18.8 0.1 5.4 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 CCM03792.1 - 8.2e-09 35.2 1.4 0.0038 17.3 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 CCM03792.1 - 0.00043 19.7 4.3 0.061 12.8 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CCM03792.1 - 0.0065 16.1 8.5 0.24 11.2 0.0 4.8 6 0 0 6 6 6 2 Kelch motif PQQ_3 PF13570.1 CCM03792.1 - 0.028 14.7 0.1 3.4 8.0 0.0 3.1 2 0 0 2 2 2 0 PQQ-like domain Exo_endo_phos PF03372.18 CCM03794.1 - 4.8e-26 92.1 0.1 6.3e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3099 PF11298.3 CCM03794.1 - 2.7 7.7 6.1 6.1 6.6 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) YesK PF14150.1 CCM03794.1 - 3.6 7.7 9.6 22 5.2 4.6 2.4 2 0 0 2 2 2 0 YesK-like protein Abhydrolase_3 PF07859.8 CCM03795.1 - 8.6e-43 146.3 0.0 1.4e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M24 PF00557.19 CCM03795.1 - 1.2e-40 139.3 0.0 1.8e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2424 PF10340.4 CCM03795.1 - 1.4e-14 53.5 0.0 1.3e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCM03795.1 - 3.2e-05 23.7 0.0 6.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCM03795.1 - 0.042 13.0 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.23 CCM03795.1 - 0.12 11.0 0.0 3.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family RibD_C PF01872.12 CCM03796.1 - 2e-27 96.1 0.0 4.3e-27 95.0 0.0 1.5 1 1 0 1 1 1 1 RibD C-terminal domain RhoGEF PF00621.15 CCM03797.1 - 3e-09 37.0 0.0 5.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain BTB PF00651.26 CCM03798.1 - 0.00094 19.1 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Aminotran_4 PF01063.14 CCM03799.1 - 4e-24 85.3 0.0 5.2e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV ZZ PF00569.12 CCM03800.1 - 3e-11 42.6 15.1 3.4e-08 32.8 4.3 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type Phage_Coat_B PF05356.6 CCM03802.1 - 0.28 10.8 4.6 4.9 6.9 0.3 3.1 3 0 0 3 3 3 0 Phage Coat protein B SNF2_N PF00176.18 CCM03805.1 - 6.8e-41 140.0 0.0 5.9e-34 117.2 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM03805.1 - 3.9e-06 26.6 0.1 7.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCM03805.1 - 0.0024 17.3 0.0 0.0076 15.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SH3_9 PF14604.1 CCM03806.1 - 2.8e-07 29.9 0.0 5.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCM03806.1 - 2e-05 23.8 0.0 3.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCM03806.1 - 0.00013 21.3 0.0 0.0003 20.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain S1FA PF04689.8 CCM03806.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA MIP-T3 PF10243.4 CCM03806.1 - 1.2 7.4 13.9 1.4 7.2 9.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Septin PF00735.13 CCM03807.1 - 1.2e-109 365.7 3.1 1.4e-109 365.4 2.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCM03807.1 - 5e-08 32.9 0.0 1.2e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCM03807.1 - 2.8e-07 29.8 0.0 4.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCM03807.1 - 2.1e-06 27.0 0.0 4.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CCM03807.1 - 8e-05 22.5 0.9 0.14 11.9 0.1 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 CCM03807.1 - 0.0001 21.8 1.6 0.002 17.6 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 CCM03807.1 - 0.00031 20.3 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 CCM03807.1 - 0.0006 18.7 0.2 0.0018 17.2 0.1 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 CCM03807.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 CCM03807.1 - 0.0046 15.8 0.1 0.011 14.5 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain IIGP PF05049.8 CCM03807.1 - 0.0093 14.8 1.4 0.055 12.2 0.0 2.3 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.1 CCM03807.1 - 0.0099 16.2 0.3 0.022 15.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM03807.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CCM03807.1 - 0.015 15.5 4.2 0.054 13.7 2.9 2.1 1 1 0 1 1 1 0 ABC transporter Miro PF08477.8 CCM03807.1 - 0.02 15.3 0.0 0.06 13.8 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 CCM03807.1 - 0.021 14.9 0.0 0.056 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 CCM03807.1 - 0.024 13.7 0.2 0.28 10.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CCM03807.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 CCM03807.1 - 0.066 12.6 0.2 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 Ras family DEAD PF00270.24 CCM03807.1 - 0.079 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_14 PF13173.1 CCM03807.1 - 0.1 12.4 2.3 0.28 11.0 0.1 2.7 3 1 0 3 3 2 0 AAA domain AAA_17 PF13207.1 CCM03807.1 - 0.12 13.1 1.4 2.4 9.0 1.0 2.4 1 1 0 1 1 1 0 AAA domain F-box-like PF12937.2 CCM03808.1 - 0.015 15.0 1.4 0.029 14.0 1.0 1.6 1 0 0 1 1 1 0 F-box-like DUF1191 PF06697.7 CCM03809.1 - 0.0043 15.8 0.0 0.009 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) PTS_EIIC PF02378.13 CCM03809.1 - 0.0072 15.1 0.2 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase system, EIIC DUF1282 PF06930.7 CCM03809.1 - 0.054 13.1 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Plasmodium_Vir PF05795.6 CCM03809.1 - 0.29 10.2 0.1 0.49 9.5 0.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein P12 PF12669.2 CCM03809.1 - 0.34 11.1 1.0 0.64 10.2 0.7 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family TauE PF01925.14 CCM03809.1 - 2.1 7.7 7.8 1.1 8.6 1.6 2.1 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE PLA2_B PF01735.13 CCM03811.1 - 1.2e-98 330.4 0.4 1.9e-98 329.8 0.3 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Cohesin_load PF10345.4 CCM03812.1 - 0.0049 15.1 0.7 1.3 7.1 0.8 3.0 3 1 0 3 3 3 2 Cohesin loading factor Cpn60_TCP1 PF00118.19 CCM03815.1 - 8.2e-147 489.7 3.7 9.4e-147 489.5 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1649 PF07855.7 CCM03816.1 - 2.9e-16 59.5 0.0 3.2e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Intein_splicing PF14890.1 CCM03817.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Intein splicing domain DUF502 PF04367.8 CCM03818.1 - 0.024 14.4 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF502) MIase PF02426.11 CCM03818.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Muconolactone delta-isomerase SNF2_N PF00176.18 CCM03819.1 - 5.4e-75 251.9 0.4 9.5e-75 251.1 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCM03819.1 - 2.5e-41 140.1 0.9 2.5e-41 140.1 0.6 2.5 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 CCM03819.1 - 5e-28 97.7 3.5 5e-28 97.7 2.4 3.3 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 CCM03819.1 - 1.5e-14 53.5 0.0 4.3e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_14 PF13173.1 CCM03819.1 - 0.0067 16.3 0.2 0.033 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_flagellin PF01917.11 CCM03819.1 - 0.037 13.6 0.1 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Archaebacterial flagellin FHA PF00498.21 CCM03820.1 - 2.4e-05 24.3 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain DLH PF01738.13 CCM03821.1 - 9.2e-17 61.0 0.0 7.9e-16 57.9 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCM03821.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family ENTH PF01417.15 CCM03822.1 - 2.9e-46 156.3 0.0 5.1e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CCM03822.1 - 6.9e-09 34.8 0.3 1.3e-08 33.9 0.2 1.5 1 1 0 1 1 1 1 ANTH domain PAT1 PF09770.4 CCM03822.1 - 0.029 12.6 28.6 0.036 12.3 19.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Vps51 PF08700.6 CCM03823.1 - 4.5e-13 48.8 0.2 1.3e-12 47.3 0.2 1.9 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 CCM03823.1 - 0.00013 21.8 0.3 0.00041 20.2 0.2 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Heme_oxygenase PF01126.15 CCM03824.1 - 0.03 13.9 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Heme oxygenase PhoU PF01895.14 CCM03824.1 - 0.043 14.2 0.4 0.043 14.2 0.3 2.0 2 1 1 3 3 3 0 PhoU domain APG6 PF04111.7 CCM03824.1 - 0.19 10.7 12.5 0.099 11.6 3.4 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 CALCOCO1 PF07888.6 CCM03824.1 - 0.31 9.2 9.3 0.022 13.0 3.0 1.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 CCM03824.1 - 2.3 7.7 14.5 1.9 8.0 4.0 2.2 2 0 0 2 2 2 0 IncA protein TBPIP PF07106.8 CCM03824.1 - 4.1 6.9 10.1 0.38 10.2 2.2 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlxA PF14282.1 CCM03824.1 - 5.5 6.9 13.8 0.14 12.1 4.4 2.1 2 1 0 2 2 2 0 FlxA-like protein DUF974 PF06159.8 CCM03825.1 - 1.7e-57 194.7 0.0 2.4e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Racemase_4 PF13615.1 CCM03825.1 - 3.4e-14 52.9 0.1 1.1e-13 51.2 0.1 2.0 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 CCM03825.1 - 2.3e-09 36.8 0.1 4.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor RTC PF01137.16 CCM03826.1 - 7.8e-50 168.7 0.1 5e-26 90.9 0.0 2.0 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CCM03826.1 - 6.1e-27 93.6 0.7 1.2e-26 92.7 0.3 1.6 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain HOOK PF05622.7 CCM03827.1 - 3.4e-59 200.4 73.2 1.1e-57 195.3 19.8 3.8 1 1 2 3 3 3 2 HOOK protein TPR_MLP1_2 PF07926.7 CCM03827.1 - 0.00012 21.8 9.3 0.00012 21.8 6.4 7.7 5 1 3 8 8 8 2 TPR/MLP1/MLP2-like protein NYD-SP28_assoc PF14775.1 CCM03827.1 - 0.0016 18.1 1.7 0.0016 18.1 1.2 4.9 4 0 0 4 4 4 1 Sperm tail C-terminal domain Rootletin PF15035.1 CCM03827.1 - 0.0058 16.6 16.6 0.0058 16.6 11.5 6.1 3 2 2 5 5 5 1 Ciliary rootlet component, centrosome cohesion TSC22 PF01166.13 CCM03827.1 - 0.0075 16.2 3.1 0.0075 16.2 2.2 7.9 7 1 1 8 8 8 2 TSC-22/dip/bun family YvfG PF09628.5 CCM03827.1 - 0.013 15.6 1.3 2.5 8.3 0.0 3.1 2 1 1 3 3 3 0 YvfG protein bZIP_1 PF00170.16 CCM03827.1 - 0.013 15.3 3.2 0.013 15.3 2.2 8.3 8 3 2 10 10 10 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 CCM03827.1 - 0.48 10.2 81.1 0.27 11.0 11.8 6.5 3 2 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CCM03827.1 - 5.5 6.0 30.7 0.03 13.5 0.5 4.6 3 1 2 5 5 5 0 Reovirus sigma C capsid protein DUF1684 PF07920.6 CCM03827.1 - 6.8 6.5 9.1 0.66 9.8 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1684) p450 PF00067.17 CCM03828.1 - 1.7e-73 247.7 0.0 2.1e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDC50 PF03381.10 CCM03829.1 - 3.3e-92 308.5 0.6 4.8e-92 308.0 0.4 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Sugar_tr PF00083.19 CCM03829.1 - 1.5e-33 116.0 2.0 2.7e-33 115.2 1.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CCM03829.1 - 2.2e-05 23.0 2.3 2.2e-05 23.0 1.6 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein DUF4282 PF14110.1 CCM03829.1 - 0.6 10.3 0.0 0.6 10.3 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4282) Glyco_hydro_88 PF07470.8 CCM03830.1 - 3.7e-09 36.0 0.0 1.6e-06 27.4 0.0 3.0 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 Abhydrolase_5 PF12695.2 CCM03831.1 - 3.8e-12 46.1 0.9 8.2e-12 45.0 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCM03831.1 - 2.2e-09 36.8 0.1 6e-09 35.4 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CCM03831.1 - 2e-06 27.8 13.7 1.5e-05 25.0 7.9 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM03831.1 - 0.00043 19.9 0.3 0.0014 18.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Tannase PF07519.6 CCM03831.1 - 0.0039 15.9 0.1 0.0072 15.0 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Esterase PF00756.15 CCM03831.1 - 0.0066 15.9 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 CCM03831.1 - 0.02 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 CCM03831.1 - 0.048 13.1 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 CCM03831.1 - 0.18 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Not1 PF04054.10 CCM03832.1 - 4.1e-109 364.9 0.0 7.3e-109 364.1 0.0 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CCM03832.1 - 1.7e-52 177.0 0.3 4.5e-52 175.6 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) XPA_C PF05181.7 CCM03832.1 - 0.024 14.1 0.2 0.06 12.9 0.1 1.7 1 0 0 1 1 1 0 XPA protein C-terminus Alpha-amylase PF00128.19 CCM03833.1 - 2.8e-46 158.3 0.0 3.8e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 CCM03833.1 - 1.5e-16 60.2 0.0 2.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) TMA7 PF09072.5 CCM03834.1 - 3.1e-24 85.1 20.0 3.4e-24 85.0 13.9 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Aldo_ket_red PF00248.16 CCM03835.1 - 2.1e-63 213.7 0.0 2.4e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family V-ATPase_H_N PF03224.9 CCM03836.1 - 3.9e-85 285.6 0.1 6e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CCM03836.1 - 1.8e-43 147.1 0.3 2e-42 143.8 0.0 2.4 2 0 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.17 CCM03836.1 - 7.3e-08 31.8 0.2 0.023 14.7 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CCM03836.1 - 5.1e-07 29.8 0.0 0.0028 17.9 0.0 3.3 3 1 0 3 3 3 2 HEAT repeats Arm_2 PF04826.8 CCM03836.1 - 1.5e-05 24.2 0.1 0.00086 18.4 0.0 2.9 3 0 0 3 3 3 1 Armadillo-like Adaptin_N PF01602.15 CCM03836.1 - 0.00033 19.0 0.5 0.076 11.3 0.4 2.9 1 1 0 1 1 1 1 Adaptin N terminal region DUF2435 PF10363.4 CCM03836.1 - 0.0074 16.1 0.5 0.39 10.6 0.2 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 CCM03836.1 - 0.011 15.6 0.1 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF2019 PF09450.5 CCM03836.1 - 0.084 12.7 0.1 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) Arm PF00514.18 CCM03836.1 - 0.27 11.1 6.5 4 7.4 0.1 4.6 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat MRP-L46 PF11788.3 CCM03837.1 - 2.5e-18 66.7 0.1 5.8e-18 65.5 0.0 1.6 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 CCM03837.1 - 9.4e-06 25.3 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Endonuclease_NS PF01223.18 CCM03838.1 - 5e-52 176.5 0.0 6.1e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease R3H PF01424.17 CCM03839.1 - 2.1e-12 46.5 0.2 4.2e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.17 CCM03839.1 - 7e-07 28.8 0.0 2.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM03839.1 - 1.3e-06 28.3 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM03839.1 - 0.00047 19.9 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_4 PF12763.2 CCM03840.1 - 4.4e-31 106.7 0.0 2.8e-15 55.9 0.0 3.6 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand GAT PF03127.9 CCM03840.1 - 2.4e-17 62.7 7.7 1.1e-05 25.2 0.1 4.2 3 2 0 3 3 3 3 GAT domain EF-hand_7 PF13499.1 CCM03840.1 - 1.3e-10 41.2 0.0 3.2e-05 23.9 0.0 4.1 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 CCM03840.1 - 1.2e-07 30.4 0.1 0.0009 18.3 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CCM03840.1 - 1.1e-05 24.9 0.0 0.034 13.7 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 CCM03840.1 - 6.7e-05 22.4 0.1 0.067 13.1 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 CCM03840.1 - 0.0014 17.8 0.0 0.004 16.4 0.0 1.8 1 0 0 1 1 1 1 EF hand PPR_2 PF13041.1 CCM03840.1 - 0.05 13.5 1.0 8.4 6.4 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family PPR PF01535.15 CCM03840.1 - 0.4 10.7 1.5 17 5.6 0.1 2.6 2 0 0 2 2 2 0 PPR repeat WD40 PF00400.27 CCM03841.1 - 2.9e-45 150.5 4.0 2.5e-07 30.3 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 CCM03841.1 - 2.8e-39 134.4 3.0 2.8e-39 134.4 2.1 3.5 3 1 0 3 3 3 1 Striatin family Nucleoporin_N PF08801.6 CCM03841.1 - 0.00018 20.3 0.1 0.012 14.4 0.0 2.8 1 1 0 3 3 3 1 Nup133 N terminal like PDEase_II PF02112.10 CCM03842.1 - 3.4e-30 105.1 0.0 3.7e-29 101.7 0.0 2.4 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II EF-hand_4 PF12763.2 CCM03843.1 - 1.3e-28 98.7 0.0 2.9e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 CCM03843.1 - 4.9e-08 32.5 0.0 9.7e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 CCM03843.1 - 2e-07 31.0 0.0 3.6e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CCM03843.1 - 0.0008 18.5 0.0 0.23 10.8 0.0 3.4 3 0 0 3 3 3 1 EF hand FliJ PF02050.11 CCM03843.1 - 0.0049 16.9 9.7 0.0049 16.9 6.7 2.7 2 1 0 3 3 3 1 Flagellar FliJ protein EF-hand_8 PF13833.1 CCM03843.1 - 0.007 15.9 0.0 0.85 9.2 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CCM03843.1 - 0.011 15.5 0.2 6.3 6.9 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain CENP-F_leu_zip PF10473.4 CCM03843.1 - 0.12 12.2 43.1 0.09 12.6 14.5 3.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UQ_con PF00179.21 CCM03844.1 - 6e-44 148.8 0.0 7.2e-44 148.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCM03844.1 - 0.0012 18.7 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Tetraspannin PF00335.15 CCM03846.1 - 0.00081 18.7 17.8 0.0062 15.8 12.8 1.9 1 1 1 2 2 2 1 Tetraspanin family VirB3 PF05101.8 CCM03846.1 - 1.8 8.6 10.2 2.3 8.2 2.0 3.3 2 1 1 3 3 3 0 Type IV secretory pathway, VirB3-like protein NAD_binding_7 PF13241.1 CCM03847.1 - 3.6e-29 101.0 0.0 8e-29 99.9 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CCM03847.1 - 2.4e-21 74.7 0.4 3.8e-21 74.1 0.3 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CCM03847.1 - 1e-14 53.1 2.6 1.7e-14 52.4 1.8 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 CCM03847.1 - 0.23 11.2 1.8 0.92 9.3 0.1 2.5 2 1 1 3 3 3 0 ThiF family MBF1 PF08523.5 CCM03848.1 - 4e-16 58.7 4.1 1.2e-11 44.4 0.7 2.6 2 0 0 2 2 2 2 Multiprotein bridging factor 1 HTH_3 PF01381.17 CCM03848.1 - 2.9e-13 49.4 0.1 4.4e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 CCM03848.1 - 2.9e-07 30.4 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 CCM03848.1 - 5.8e-05 23.1 0.0 0.00013 22.0 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.1 CCM03848.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HDPD PF02924.9 CCM03848.1 - 0.081 12.7 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D Tubulin PF00091.20 CCM03849.1 - 2.7e-74 249.6 0.0 4.6e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCM03849.1 - 1.3e-47 160.9 0.1 2.5e-47 160.0 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCM03849.1 - 0.0004 20.4 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CCM03849.1 - 0.0084 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RNA12 PF10443.4 CCM03851.1 - 4.9e-116 387.7 0.2 1.8e-115 385.8 0.1 1.9 1 1 0 1 1 1 1 RNA12 protein AAA_16 PF13191.1 CCM03851.1 - 2.1e-06 27.8 1.0 0.0006 19.8 0.2 3.0 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 CCM03851.1 - 0.00019 21.2 0.0 0.0015 18.2 0.0 2.1 1 1 0 2 2 2 1 Archaeal ATPase AAA_19 PF13245.1 CCM03851.1 - 0.0011 18.6 0.3 0.76 9.5 0.1 2.9 2 0 0 2 2 2 2 Part of AAA domain DUF815 PF05673.8 CCM03851.1 - 0.0088 14.9 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CCM03851.1 - 0.036 13.9 0.3 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CCM03851.1 - 0.036 14.1 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RRM_5 PF13893.1 CCM03851.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_29 PF13555.1 CCM03851.1 - 0.082 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 CCM03851.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.17 CCM03851.1 - 0.12 11.9 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SSF PF00474.12 CCM03852.1 - 3e-18 65.6 34.9 5.3e-18 64.8 24.2 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2663 PF10864.3 CCM03852.1 - 0.0073 16.5 1.9 0.1 12.8 0.4 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2663) DUF2207 PF09972.4 CCM03852.1 - 0.12 10.9 0.0 0.12 10.9 0.0 3.4 4 1 0 4 4 4 0 Predicted membrane protein (DUF2207) Sec7 PF01369.15 CCM03853.1 - 4.9e-62 208.9 0.0 8e-62 208.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CCM03853.1 - 8.7e-21 74.0 0.7 8.2e-10 38.3 0.2 2.8 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCM03853.1 - 0.012 15.1 0.7 0.69 9.4 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1981) Epimerase PF01370.16 CCM03854.1 - 0.0011 18.4 0.0 0.0041 16.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Bac_rhodopsin PF01036.13 CCM03855.1 - 3.1e-38 131.2 26.9 3.9e-38 130.9 18.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MMR_HSR1 PF01926.18 CCM03856.1 - 3.1e-08 33.5 0.1 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 CCM03856.1 - 2.8e-06 26.6 0.0 5.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 CCM03856.1 - 5.3e-06 25.8 0.1 1.7e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 CCM03856.1 - 0.00019 20.6 0.1 0.00047 19.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 CCM03856.1 - 0.00033 19.7 0.7 0.00064 18.8 0.0 1.7 2 0 0 2 2 2 1 Septin AAA_23 PF13476.1 CCM03856.1 - 0.0017 18.7 4.1 0.098 12.9 0.7 2.3 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 CCM03856.1 - 0.033 14.0 4.6 0.48 10.2 0.0 3.1 2 1 1 3 3 3 0 Dynamin family Nup54 PF13874.1 CCM03856.1 - 0.074 12.7 6.3 0.13 11.9 4.3 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ABC_tran PF00005.22 CCM03856.1 - 0.08 13.2 0.6 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter DUF87 PF01935.12 CCM03856.1 - 0.39 10.4 2.2 2.3 7.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 GreA_GreB_N PF03449.10 CCM03856.1 - 0.44 10.6 8.8 0.17 11.9 4.1 1.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal IncA PF04156.9 CCM03856.1 - 0.62 9.6 4.0 1 8.9 2.8 1.4 1 0 0 1 1 1 0 IncA protein DUF922 PF06037.6 CCM03856.1 - 0.66 9.2 3.7 1.3 8.3 2.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) ATP_bind_1 PF03029.12 CCM03856.1 - 0.79 9.2 3.9 1.4 8.3 0.3 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AIG1 PF04548.11 CCM03857.1 - 1.2e-09 37.6 1.0 1.2e-09 37.6 0.7 1.9 1 1 1 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 CCM03857.1 - 4.6e-09 36.2 0.1 1.2e-08 34.9 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCM03857.1 - 5.2e-05 22.4 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCM03857.1 - 8.5e-05 22.4 13.0 0.037 13.8 0.1 3.5 2 2 1 3 3 3 2 Dynamin family AAA_17 PF13207.1 CCM03857.1 - 0.00028 21.7 1.1 0.0012 19.6 0.7 2.3 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CCM03857.1 - 0.0012 18.1 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCM03857.1 - 0.0017 18.8 1.1 0.0076 16.7 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 CCM03857.1 - 0.0027 18.0 3.8 0.023 15.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain Septin PF00735.13 CCM03857.1 - 0.0034 16.4 0.0 0.0034 16.4 0.0 2.3 2 1 0 2 2 2 1 Septin T2SE PF00437.15 CCM03857.1 - 0.0047 15.8 0.1 0.012 14.5 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 CCM03857.1 - 0.0053 16.7 3.0 0.055 13.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CCM03857.1 - 0.0055 17.0 13.3 0.016 15.5 9.2 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCM03857.1 - 0.0074 15.4 0.0 0.0074 15.4 0.0 2.7 2 1 1 3 3 3 1 Zeta toxin AAA_29 PF13555.1 CCM03857.1 - 0.028 13.9 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCM03857.1 - 0.036 14.3 6.4 0.67 10.2 4.4 2.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 CCM03857.1 - 0.036 13.7 0.7 1.7 8.2 0.2 3.0 2 1 1 4 4 4 0 NACHT domain FtsK_SpoIIIE PF01580.13 CCM03857.1 - 0.067 12.6 1.8 0.071 12.5 0.0 1.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family APG6 PF04111.7 CCM03857.1 - 0.1 11.6 8.9 1.5 7.7 6.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 AAA_25 PF13481.1 CCM03857.1 - 0.14 11.5 1.2 0.63 9.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain FAD_syn PF06574.7 CCM03857.1 - 0.15 11.6 0.7 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 FAD synthetase AAA_33 PF13671.1 CCM03857.1 - 0.18 11.6 0.2 0.18 11.6 0.1 2.5 2 2 1 3 3 3 0 AAA domain AAA_22 PF13401.1 CCM03857.1 - 0.79 9.8 4.1 0.36 10.9 0.2 2.4 2 2 0 2 2 2 0 AAA domain IncA PF04156.9 CCM03857.1 - 0.84 9.2 9.8 1.6 8.3 6.8 1.4 1 0 0 1 1 1 0 IncA protein AAA_10 PF12846.2 CCM03857.1 - 2.2 7.6 10.5 21 4.4 7.3 2.6 1 1 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 CCM03857.1 - 2.3 8.0 13.7 1.2 8.9 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF87 OmpH PF03938.9 CCM03857.1 - 2.4 8.0 11.6 0.67 9.8 6.0 1.7 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) AIG1 PF04548.11 CCM03859.1 - 0.045 12.8 0.1 0.084 11.9 0.0 1.6 1 1 0 1 1 1 0 AIG1 family Fmp27_WPPW PF10359.4 CCM03859.1 - 0.084 11.2 4.4 0.12 10.8 3.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Dynamin_N PF00350.18 CCM03859.1 - 0.13 12.0 0.1 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Dynamin family OmpH PF03938.9 CCM03859.1 - 0.43 10.4 8.1 0.81 9.6 5.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.7 CCM03859.1 - 0.47 8.8 1.8 0.61 8.4 1.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 CCM03859.1 - 0.84 7.9 4.7 1.2 7.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V-SNARE PF05008.10 CCM03859.1 - 1 9.5 9.0 1.9 8.6 6.2 1.5 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Strep_SA_rep PF06696.6 CCM03859.1 - 3 7.6 6.1 0.24 11.1 0.5 2.0 2 0 0 2 2 2 0 Streptococcal surface antigen repeat IncA PF04156.9 CCM03859.1 - 3.1 7.3 14.4 10 5.6 10.0 1.8 1 1 0 1 1 1 0 IncA protein DUF724 PF05266.9 CCM03859.1 - 4.3 6.9 9.0 9.1 5.8 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF612 PF04747.7 CCM03859.1 - 4.5 6.0 5.7 6.9 5.4 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF612 NAD_binding_2 PF03446.10 CCM03860.1 - 3.7e-36 124.4 0.2 5.1e-36 123.9 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CCM03860.1 - 6.3e-34 116.6 0.0 1.2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Coiled PF05710.7 CCM03860.1 - 3 8.3 8.2 0.66 10.4 1.9 2.5 2 1 0 2 2 2 0 Coiled coil Cytochrom_B561 PF03188.11 CCM03861.1 - 8e-07 28.9 8.9 8e-07 28.9 6.2 2.9 1 1 2 3 3 3 2 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 CCM03861.1 - 0.0036 17.0 0.7 0.0036 17.0 0.5 3.5 3 0 0 3 3 3 1 PepSY-associated TM helix DUF2306 PF10067.4 CCM03861.1 - 2.1 8.4 17.5 1.3 9.1 0.8 3.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Pkinase PF00069.20 CCM03862.1 - 2.1e-21 76.2 0.0 4.2e-21 75.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03862.1 - 2.2e-11 43.3 0.0 4.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DEAD PF00270.24 CCM03863.1 - 1.5e-18 66.8 0.0 2.7e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 CCM03863.1 - 1.2e-12 48.2 0.6 4e-12 46.5 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 CCM03863.1 - 6.1e-10 38.8 0.1 2.7e-08 33.5 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CDT1 PF08839.6 CCM03863.1 - 4.3e-07 30.0 0.0 8.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like Abhydrolase_6 PF12697.2 CCM03864.1 - 4.3e-32 111.8 0.0 6.8e-32 111.1 0.0 1.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM03864.1 - 4.9e-21 75.3 0.0 7e-19 68.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM03864.1 - 4e-15 55.8 0.0 5.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCM03864.1 - 4.6e-06 26.3 0.0 1.4e-05 24.7 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCM03864.1 - 0.0051 16.6 0.0 0.045 13.5 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 CCM03864.1 - 0.0052 16.6 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 CCM03864.1 - 0.012 14.7 0.1 2 7.6 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.15 CCM03864.1 - 0.015 15.5 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.6 CCM03864.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SPT16 PF08644.6 CCM03865.1 - 2.1e-56 189.9 1.1 4.8e-56 188.8 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CCM03865.1 - 3.5e-32 111.2 0.0 1.4e-30 105.9 0.0 2.7 1 1 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CCM03865.1 - 9.1e-25 87.4 0.0 1.7e-24 86.5 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CCM03865.1 - 1.1e-20 73.3 0.0 6.2e-20 70.9 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like AMP-binding PF00501.23 CCM03866.1 - 4e-14 51.8 0.3 1.5e-08 33.5 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DUF2420 PF10336.4 CCM03867.1 - 3.4e-11 42.7 0.8 1.8e-10 40.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Zip PF02535.17 CCM03867.1 - 2.2 7.2 3.2 4.4 6.2 2.2 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.27 CCM03868.1 - 1.1e-74 243.8 16.2 4.2e-12 45.4 0.1 9.0 9 0 0 9 9 9 8 WD domain, G-beta repeat PD40 PF07676.7 CCM03868.1 - 3.3e-07 29.8 6.0 6.6 6.5 0.0 6.7 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 CCM03868.1 - 0.00031 19.0 6.1 0.52 8.3 0.1 4.0 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 CCM03868.1 - 0.00073 18.7 0.8 9.8 5.1 0.0 4.6 2 2 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 CCM03868.1 - 0.02 13.2 1.1 0.69 8.1 0.1 3.3 2 2 2 4 4 4 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 CCM03868.1 - 0.042 13.1 9.6 6.6 6.1 0.0 6.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Ribonuclease PF00545.15 CCM03868.1 - 0.069 13.2 0.0 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 ribonuclease Nucleoporin_N PF08801.6 CCM03868.1 - 0.084 11.6 0.1 6.3 5.4 0.1 2.8 2 1 1 3 3 3 0 Nup133 N terminal like IKI3 PF04762.7 CCM03868.1 - 0.15 9.8 0.0 0.42 8.3 0.0 1.8 2 0 0 2 2 2 0 IKI3 family DUF1258 PF06869.7 CCM03868.1 - 0.21 10.6 0.1 57 2.6 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1258) Meth_synt_2 PF01717.13 CCM03870.1 - 5.1e-20 71.7 0.0 2.2e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCM03870.1 - 2.9e-08 33.3 0.0 0.0038 16.5 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Glyco_hydro_92 PF07971.7 CCM03871.1 - 4.1e-149 497.4 2.4 5.2e-149 497.1 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DnaJ PF00226.26 CCM03872.1 - 1.9e-20 72.3 3.9 2.3e-20 72.0 0.2 2.7 3 0 0 3 3 2 1 DnaJ domain TPR_19 PF14559.1 CCM03872.1 - 6.2e-11 42.4 12.3 0.2 12.0 0.5 5.9 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 CCM03872.1 - 8.4e-11 41.3 15.7 0.00019 21.0 0.6 5.7 5 2 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 CCM03872.1 - 2.5e-09 36.3 1.0 0.00038 19.9 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM03872.1 - 3.4e-09 37.1 11.2 0.00035 21.1 0.3 4.7 4 1 1 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 CCM03872.1 - 3.3e-08 33.5 1.2 0.0068 16.5 0.0 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CCM03872.1 - 1.5e-07 30.7 13.1 0.022 14.6 0.1 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCM03872.1 - 2.6e-07 30.4 8.6 0.0054 16.5 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM03872.1 - 2.4e-05 24.5 14.8 0.083 13.5 0.1 6.5 6 2 2 8 8 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCM03872.1 - 0.00012 21.6 8.8 1.1 9.2 0.1 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCM03872.1 - 0.00055 19.5 1.5 3.4 7.6 0.1 5.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCM03872.1 - 0.00089 19.5 7.9 2.6 8.6 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCM03872.1 - 0.002 18.0 13.0 0.0079 16.1 0.5 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 CCM03872.1 - 0.0028 17.9 2.3 8.5 7.1 0.3 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCM03872.1 - 0.039 14.1 5.9 55 4.3 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat DIOX_N PF14226.1 CCM03873.1 - 1.7e-15 57.5 0.0 3.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM03873.1 - 1.2e-13 51.1 0.0 2.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.6 CCM03875.1 - 4.7e-16 58.0 0.2 7e-16 57.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CCM03875.1 - 1.4e-14 53.7 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.13 CCM03875.1 - 8.1e-06 25.5 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.7 CCM03875.1 - 1.3e-05 24.5 0.1 2.2e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) LTD PF00932.14 CCM03875.1 - 0.016 15.3 0.2 0.049 13.6 0.0 2.1 2 1 0 2 2 2 0 Lamin Tail Domain GPI PF06560.6 CCM03875.1 - 0.042 12.8 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_8 PF13621.1 CCM03875.1 - 0.057 12.8 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Cupin-like domain Glyoxalase PF00903.20 CCM03877.1 - 1.6e-27 96.0 0.1 1.9e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CCM03877.1 - 3.7e-17 62.8 0.0 4.7e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CCM03877.1 - 3.8e-09 36.5 0.0 5.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CCM03877.1 - 0.00084 19.2 0.0 0.0022 17.9 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 CCM03878.1 - 1.5e-19 70.2 0.0 2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CCM03878.1 - 3.3e-14 53.3 0.0 4.2e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CCM03878.1 - 2.2e-06 27.6 0.0 0.00071 19.5 0.0 1.7 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PC-Esterase PF13839.1 CCM03879.1 - 3.3e-07 30.3 0.0 1.5e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Acetyltransf_1 PF00583.19 CCM03880.1 - 3e-09 36.7 0.0 8.4e-09 35.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCM03880.1 - 2.6e-07 30.7 0.0 1e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCM03880.1 - 0.00012 21.7 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 CCM03880.1 - 0.00031 20.5 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 CCM03880.1 - 0.00047 20.2 0.0 0.0014 18.7 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCM03880.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TAN PF11640.3 CCM03881.1 - 0.0078 15.9 0.2 2.8 7.6 0.0 2.1 1 1 1 2 2 2 2 Telomere-length maintenance and DNA damage repair Auxin_inducible PF02519.9 CCM03881.1 - 0.014 15.3 0.1 5.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Auxin responsive protein DUF3417 PF11897.3 CCM03881.1 - 0.018 14.9 0.9 0.98 9.3 0.1 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) D-ser_dehydrat PF14031.1 CCM03881.1 - 0.058 13.5 0.0 15 5.8 0.0 2.2 2 0 0 2 2 2 0 Putative serine dehydratase domain Fungal_trans PF04082.13 CCM03882.1 - 3.4e-11 42.5 0.5 3.4e-11 42.5 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM03882.1 - 0.0098 15.7 4.2 0.018 14.9 2.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 CCM03882.1 - 0.016 14.3 2.5 0.043 13.0 1.7 1.7 1 0 0 1 1 1 0 Copper fist DNA binding domain Glyco_hydro_18 PF00704.23 CCM03883.1 - 1.8e-61 208.5 5.6 2.3e-61 208.1 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FA_hydroxylase PF04116.8 CCM03884.1 - 2.1e-12 47.4 20.7 2.1e-12 47.4 14.4 2.3 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Mating_N PF12731.2 CCM03884.1 - 0.088 12.6 0.5 0.97 9.3 0.0 2.4 2 0 0 2 2 2 0 Mating-type protein beta 1 FUSC_2 PF13515.1 CCM03886.1 - 3e-24 85.3 9.2 3e-24 85.3 6.4 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 CCM03886.1 - 7.2e-17 61.0 21.9 2.2e-13 49.5 3.5 4.5 4 0 0 4 4 4 3 Fusaric acid resistance protein family ALMT PF11744.3 CCM03886.1 - 1.1e-12 47.3 7.1 5.6e-10 38.4 3.3 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 CCM03886.1 - 3e-11 43.3 0.2 1.7e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 CCM03886.1 - 0.0022 17.8 1.4 0.0022 17.8 1.0 3.0 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF939) API5 PF05918.6 CCM03887.1 - 2.6e-15 55.9 0.1 4.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 CCM03887.1 - 5.5e-05 23.3 0.5 0.00017 21.7 0.2 2.1 2 0 0 2 2 2 1 HEAT repeats Adaptin_N PF01602.15 CCM03887.1 - 0.0033 15.8 0.0 0.0055 15.0 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cyt-b5 PF00173.23 CCM03888.1 - 5.7e-14 51.6 0.1 7.6e-14 51.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain G-alpha PF00503.15 CCM03889.1 - 3.3e-125 417.8 0.3 4e-125 417.5 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCM03889.1 - 1.9e-16 59.7 1.8 7.8e-12 44.7 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCM03889.1 - 8.5e-05 21.7 0.7 0.0081 15.3 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCM03889.1 - 0.0002 21.8 0.1 0.16 12.4 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CCM03889.1 - 0.014 15.3 0.1 0.54 10.2 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CCM03889.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CCM03889.1 - 0.033 13.6 0.1 6.4 6.1 0.0 2.6 1 1 2 3 3 3 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 CCM03889.1 - 0.085 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family BCS1_N PF08740.6 CCM03890.1 - 9.4e-30 103.6 1.8 2e-29 102.5 1.2 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CCM03890.1 - 6.2e-15 55.5 0.3 6.2e-07 29.6 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CCM03890.1 - 9.7e-05 21.4 0.0 0.00022 20.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 CCM03890.1 - 0.00064 19.2 0.1 0.013 15.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CCM03890.1 - 0.00079 19.4 0.0 0.00079 19.4 0.0 2.6 2 1 0 2 2 1 1 AAA ATPase domain Macoilin PF09726.4 CCM03890.1 - 0.0011 17.3 7.9 0.0018 16.6 5.4 1.2 1 0 0 1 1 1 1 Transmembrane protein CAF-1_p150 PF11600.3 CCM03890.1 - 0.0045 16.3 21.7 0.0045 16.3 15.0 2.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_17 PF13207.1 CCM03890.1 - 0.037 14.8 6.6 0.043 14.6 0.0 3.1 3 1 0 3 3 3 0 AAA domain DUF4262 PF14081.1 CCM03890.1 - 0.044 13.8 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) Viral_helicase1 PF01443.13 CCM03890.1 - 0.066 12.7 0.1 0.21 11.0 0.0 1.8 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 CCM03890.1 - 0.071 12.9 1.3 0.19 11.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CCM03890.1 - 0.092 13.0 1.9 0.14 12.5 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 CCM03890.1 - 0.13 12.6 10.1 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain HTH_29 PF13551.1 CCM03892.1 - 1 9.5 4.0 0.43 10.7 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix DIOX_N PF14226.1 CCM03893.1 - 1.1e-28 100.0 0.1 1.9e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM03893.1 - 8.1e-17 61.3 0.0 1.5e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PWWP PF00855.12 CCM03895.1 - 1.3e-18 66.9 1.2 2.3e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 CCM03895.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain DUF1675 PF07897.6 CCM03895.1 - 1.6 8.5 16.6 1.1 9.1 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Sec2p PF06428.6 CCM03896.1 - 2.8e-08 33.5 12.4 2.8e-08 33.5 8.6 2.9 3 2 1 4 4 3 1 GDP/GTP exchange factor Sec2p SPX PF03105.14 CCM03896.1 - 0.051 13.3 7.8 0.14 11.9 5.4 1.8 1 1 0 1 1 1 0 SPX domain APG6 PF04111.7 CCM03896.1 - 0.15 11.1 7.9 0.38 9.7 5.5 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 CCM03896.1 - 0.17 10.5 10.6 0.34 9.5 7.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.4 CCM03896.1 - 0.23 9.8 6.6 0.44 8.8 4.6 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF342 PF03961.8 CCM03896.1 - 0.27 9.6 4.0 0.56 8.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Herpes_UL25 PF01499.11 CCM03896.1 - 0.3 9.3 10.7 0.13 10.5 1.5 2.3 1 1 1 2 2 2 0 Herpesvirus UL25 family V_ATPase_I PF01496.14 CCM03896.1 - 0.61 7.8 2.2 0.94 7.2 1.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps51 PF08700.6 CCM03896.1 - 0.69 9.7 8.0 4.2 7.2 2.9 3.0 2 1 0 2 2 2 0 Vps51/Vps67 DUF4140 PF13600.1 CCM03896.1 - 0.76 10.2 20.3 0.26 11.7 0.8 3.6 4 1 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) DUF501 PF04417.7 CCM03896.1 - 3.4 7.5 7.9 1 9.1 2.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF501) Exonuc_VII_L PF02601.10 CCM03896.1 - 8.6 5.4 9.9 0.59 9.2 2.3 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Pkinase PF00069.20 CCM03897.1 - 2.9e-12 46.3 0.0 5.9e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03897.1 - 0.0044 16.1 0.0 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CCM03897.1 - 0.082 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2348 PF09807.4 CCM03898.1 - 3.6e-09 36.0 0.0 4.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) MMtag PF10159.4 CCM03899.1 - 1.9e-31 107.9 3.5 1.9e-31 107.9 2.4 3.3 3 0 0 3 3 3 1 Kinase phosphorylation protein GAGA_bind PF06217.7 CCM03899.1 - 0.25 11.2 7.8 0.37 10.6 5.4 1.4 1 1 0 1 1 1 0 GAGA binding protein-like family DEAD PF00270.24 CCM03901.1 - 1.9e-08 33.9 0.3 3.4e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 CCM03901.1 - 3e-05 23.5 0.4 0.00011 21.7 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 CCM03901.1 - 7.6e-05 22.8 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCM03901.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 CCM03901.1 - 0.0092 15.8 0.1 4.3 7.1 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.11 CCM03901.1 - 0.018 14.2 0.1 0.097 11.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 CCM03901.1 - 0.028 13.9 0.0 0.049 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCM03901.1 - 0.031 14.5 0.1 0.064 13.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.9 CCM03901.1 - 0.04 13.6 0.1 0.078 12.7 0.1 1.5 1 1 0 1 1 1 0 Flavivirus DEAD domain Myosin_head PF00063.16 CCM03901.1 - 0.047 11.7 0.0 0.058 11.4 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Zeta_toxin PF06414.7 CCM03901.1 - 0.062 12.3 0.0 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF2758 PF10957.3 CCM03901.1 - 0.074 12.8 0.0 19 5.1 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2758) KaiC PF06745.8 CCM03901.1 - 0.096 11.7 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CCM03901.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCM03901.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CCM03901.1 - 0.15 11.8 0.3 0.31 10.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CCM03901.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 CCM03901.1 - 0.17 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 CCM03902.1 - 4.9e-06 26.2 12.7 0.011 15.6 0.0 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat adh_short PF00106.20 CCM03903.1 - 2.6e-11 43.7 8.6 6.1e-07 29.5 0.2 2.8 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCM03903.1 - 7.4e-05 22.4 3.5 0.00024 20.7 0.1 2.7 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CCM03903.1 - 0.00017 21.4 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM03903.1 - 0.00078 19.5 4.1 0.021 14.8 0.2 2.8 2 1 1 3 3 3 2 NADH(P)-binding Semialdhyde_dh PF01118.19 CCM03903.1 - 0.04 14.2 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CCM03903.1 - 0.061 12.2 0.0 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Hydrophobin PF01185.13 CCM03904.1 - 3.6e-16 59.3 6.2 6.3e-16 58.5 4.3 1.4 1 0 0 1 1 1 1 Fungal hydrophobin DUF605 PF04652.11 CCM03904.1 - 0.41 10.0 14.8 0.48 9.7 10.3 1.2 1 0 0 1 1 1 0 Vta1 like Toxin_12 PF07740.7 CCM03904.1 - 1.1 9.7 6.7 3.2 8.3 0.2 2.5 2 1 0 2 2 2 0 Ion channel inhibitory toxin ABC_tran PF00005.22 CCM03907.1 - 2.6e-48 163.8 0.0 2.7e-28 98.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCM03907.1 - 1.3e-34 119.8 39.8 4.4e-19 68.9 9.0 4.2 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 CCM03907.1 - 4.4e-12 45.7 3.0 0.0048 16.1 0.3 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCM03907.1 - 4.1e-11 43.3 2.1 0.016 15.1 0.1 4.2 2 2 0 3 3 3 3 AAA domain AAA_23 PF13476.1 CCM03907.1 - 7.3e-09 36.2 0.6 0.00013 22.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 CCM03907.1 - 5.4e-08 32.4 0.0 0.0074 15.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 CCM03907.1 - 5.8e-07 28.9 0.0 0.039 13.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CCM03907.1 - 6.9e-06 26.1 2.8 0.057 13.4 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CCM03907.1 - 4.2e-05 23.1 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 CCM03907.1 - 6.5e-05 21.9 0.1 0.024 13.5 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein Miro PF08477.8 CCM03907.1 - 7.7e-05 23.1 0.1 0.3 11.5 0.0 3.3 3 1 0 3 3 2 1 Miro-like protein MobB PF03205.9 CCM03907.1 - 7.8e-05 22.4 0.3 0.63 9.7 0.1 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CCM03907.1 - 8.2e-05 22.4 0.0 0.015 15.0 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 CCM03907.1 - 0.00015 22.5 0.6 0.66 10.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCM03907.1 - 0.00018 21.4 0.4 0.21 11.5 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCM03907.1 - 0.00065 18.9 0.0 0.63 9.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCM03907.1 - 0.00071 19.7 1.7 0.29 11.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 CCM03907.1 - 0.00095 17.9 0.0 0.0066 15.1 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein DUF87 PF01935.12 CCM03907.1 - 0.0012 18.7 1.3 0.07 12.9 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 CCM03907.1 - 0.0018 17.7 3.3 1.4 8.2 0.0 3.1 2 1 1 3 3 3 2 AAA-like domain AAA_18 PF13238.1 CCM03907.1 - 0.002 18.4 0.0 2.3 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCM03907.1 - 0.0023 17.3 0.2 1.9 7.8 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCM03907.1 - 0.0067 15.5 0.0 0.37 9.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.1 CCM03907.1 - 0.0069 15.9 0.0 0.031 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM03907.1 - 0.012 15.3 0.0 1 9.1 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 CCM03907.1 - 0.015 15.1 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 CCM03907.1 - 0.02 14.6 0.3 8 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 CCM03907.1 - 0.021 14.6 0.1 3.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Dynamin family DEAD PF00270.24 CCM03907.1 - 0.024 14.1 0.1 6.7 6.1 0.1 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase Pox_A32 PF04665.7 CCM03907.1 - 0.031 13.5 0.4 4.2 6.5 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 CCM03907.1 - 0.061 13.2 0.1 0.77 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCM03907.1 - 0.063 13.4 0.8 1.8 8.7 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 CCM03907.1 - 0.17 10.9 0.0 0.33 9.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 CCM03907.1 - 0.36 10.2 2.7 1.2 8.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CCM03907.1 - 0.87 9.2 4.9 2.9 7.5 0.1 3.1 3 0 0 3 3 3 0 NACHT domain Peptidase_M56 PF05569.6 CCM03908.1 - 0.14 11.1 0.0 0.14 11.1 0.0 1.9 1 1 1 2 2 2 0 BlaR1 peptidase M56 DctQ PF04290.7 CCM03908.1 - 6.3 6.5 11.2 0.095 12.4 1.2 2.6 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DoxD PF04173.8 CCM03908.1 - 7.2 6.2 8.5 2.8 7.5 0.4 3.1 1 1 2 3 3 3 0 TQO small subunit DoxD Lipase_GDSL_2 PF13472.1 CCM03909.1 - 3.7e-30 105.3 0.9 4.5e-30 105.1 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CCM03909.1 - 3.7e-25 89.1 0.0 4.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HECT PF00632.20 CCM03910.1 - 1.3e-91 307.0 0.0 1.8e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CCM03910.1 - 9.3e-35 118.1 21.5 1.4e-11 43.9 4.1 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CCM03910.1 - 3.8e-14 52.2 0.1 8.8e-14 51.1 0.1 1.7 1 0 0 1 1 1 1 C2 domain MHC_II_alpha PF00993.15 CCM03910.1 - 0.0084 15.6 0.4 0.11 12.1 0.0 3.0 4 0 0 4 4 4 1 Class II histocompatibility antigen, alpha domain Peptidase_M1 PF01433.15 CCM03911.1 - 1.2e-85 287.9 0.0 7.3e-48 163.5 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 CCM03911.1 - 1.3e-57 195.5 0.4 1.9e-57 194.9 0.3 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCM03911.1 - 2.5e-05 24.3 0.2 0.0011 19.0 0.1 2.6 1 1 0 1 1 1 1 Peptidase MA superfamily Bestrophin PF01062.16 CCM03913.1 - 9.5e-48 162.6 0.2 1.9e-26 92.6 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel 2Fe-2S_thioredx PF01257.14 CCM03914.1 - 5.1e-57 191.5 0.1 6.2e-57 191.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Pkinase PF00069.20 CCM03915.1 - 5e-62 209.4 0.0 5.8e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM03915.1 - 1.1e-24 86.9 0.0 1.4e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM03915.1 - 0.00022 20.2 0.0 0.00041 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CCM03915.1 - 0.0069 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CCM03915.1 - 0.0096 15.6 0.0 0.031 14.0 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.27 CCM03916.1 - 4.8e-52 172.0 24.5 1.3e-09 37.5 0.1 8.5 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 CCM03916.1 - 8.9e-13 47.7 1.8 9.2e-13 47.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 CCM03916.1 - 7.3e-11 40.9 12.6 0.0013 16.9 0.2 5.3 1 1 3 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.28 CCM03916.1 - 1.6e-10 40.3 0.1 3.9e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain zf-CCHC PF00098.18 CCM03916.1 - 8.2 6.5 13.2 0.43 10.5 4.0 2.7 2 0 0 2 2 2 0 Zinc knuckle MIF4G PF02854.14 CCM03917.1 - 4.4e-50 170.0 0.2 8.4e-50 169.0 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CCM03917.1 - 8.5e-18 64.0 0.6 4.9e-17 61.5 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 CCM03917.1 - 2.7e-08 33.5 0.3 1.1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 MA3 domain MIP-T3 PF10243.4 CCM03917.1 - 8.1e-06 24.5 43.6 8.1e-06 24.5 30.2 2.2 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 DUF4064 PF13273.1 CCM03918.1 - 0.15 12.1 8.9 0.39 10.8 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3445 PF11927.3 CCM03919.1 - 4e-58 196.7 0.0 5.1e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF2678 PF10856.3 CCM03920.1 - 0.45 10.2 3.6 0.11 12.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Cupredoxin_1 PF13473.1 CCM03922.1 - 0.092 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain FAD_binding_3 PF01494.14 CCM03923.1 - 1.1e-78 264.8 0.0 1.4e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 CCM03923.1 - 5e-05 22.3 0.1 0.0096 14.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 CCM03923.1 - 0.00019 20.6 0.0 0.00036 19.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CCM03923.1 - 0.00026 20.9 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM03923.1 - 0.0015 18.4 0.0 0.0048 16.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCM03923.1 - 0.0045 15.5 0.2 0.028 12.9 0.0 2.2 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 CCM03923.1 - 0.0057 17.0 0.5 1.3 9.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 CCM03923.1 - 0.019 14.7 0.0 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 CCM03923.1 - 0.08 11.7 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CCM03923.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_8 PF01501.15 CCM03924.1 - 9.3e-15 54.6 0.0 1.6e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_30 PF05430.6 CCM03924.1 - 0.072 12.7 0.0 10 5.7 0.0 2.9 3 0 0 3 3 3 0 S-adenosyl-L-methionine-dependent methyltransferase Nucleotid_trans PF03407.11 CCM03924.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_transf_8 PF01501.15 CCM03925.1 - 8e-16 58.1 0.0 1.5e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 CATSPERB PF15149.1 CCM03925.1 - 0.17 10.0 0.1 0.23 9.5 0.1 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family UPF0029 PF01205.14 CCM03926.1 - 1.1e-15 57.2 0.0 2.3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF221 PF02714.10 CCM03927.1 - 3.9e-89 298.7 22.3 3.9e-89 298.7 15.5 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCM03927.1 - 3.9e-37 127.2 2.1 3.9e-37 127.2 1.4 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CCM03927.1 - 2.2e-17 63.3 0.1 4.7e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Glyco_transf_8 PF01501.15 CCM03928.1 - 1.3e-18 67.2 0.0 2.4e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 CCM03928.1 - 0.024 14.4 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_transf_8 PF01501.15 CCM03929.1 - 1.9e-17 63.4 0.0 3.4e-17 62.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 CCM03929.1 - 0.0088 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PPR_3 PF13812.1 CCM03930.1 - 4.4e-12 45.2 9.6 0.0063 16.7 0.0 7.3 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 CCM03930.1 - 2.5e-08 33.7 0.0 0.00064 19.6 0.0 4.9 3 2 1 4 4 4 1 PPR repeat family PPR PF01535.15 CCM03930.1 - 0.015 15.1 5.3 2 8.5 0.2 5.5 6 1 0 6 6 6 0 PPR repeat FSH1 PF03959.8 CCM03931.1 - 1.6e-43 148.5 0.0 1.1e-42 145.9 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 CCM03931.1 - 1.3e-07 31.7 0.3 0.00064 19.6 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM03931.1 - 2.9e-06 27.1 0.0 7.6e-06 25.7 0.0 1.6 1 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CCM03931.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 CCM03931.1 - 0.084 11.7 0.0 8.5 5.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) PE-PPE PF08237.6 CCM03931.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain HEAT PF02985.17 CCM03932.1 - 3.2e-22 76.5 12.0 2.1e-05 24.2 0.0 10.0 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 CCM03932.1 - 9.7e-20 70.6 1.1 8.4e-05 22.7 0.0 7.7 5 3 3 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 CCM03932.1 - 2e-19 69.4 22.3 4e-12 46.2 0.0 9.6 8 3 3 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCM03932.1 - 7e-10 39.1 0.0 0.026 14.8 0.0 5.4 5 1 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CCM03932.1 - 2e-06 27.7 1.3 0.089 12.6 0.1 5.6 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CCM03932.1 - 4.2e-05 23.1 1.4 0.22 11.3 0.0 5.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 CCM03932.1 - 0.00032 20.5 0.9 1.9 8.5 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 CCM03932.1 - 0.0052 15.1 1.0 1 7.6 0.1 3.6 4 0 0 4 4 4 1 Adaptin N terminal region DUF3437 PF11919.3 CCM03932.1 - 0.016 14.9 0.0 7.3 6.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) CLASP_N PF12348.3 CCM03932.1 - 0.11 11.8 0.0 49 3.1 0.0 3.6 4 1 0 4 4 4 0 CLASP N terminal RRM_6 PF14259.1 CCM03933.1 - 1.8e-36 123.9 0.5 9.7e-11 41.4 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCM03933.1 - 5.9e-28 96.3 2.5 4.8e-09 35.7 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM03933.1 - 1.3e-16 60.1 0.0 0.0003 20.5 0.1 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCM03933.1 - 5.1e-05 23.0 1.2 0.066 13.0 0.1 2.6 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 CCM03933.1 - 0.017 14.9 0.0 0.22 11.2 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Hydrolase_4 PF12146.3 CCM03934.1 - 1.4e-15 56.8 1.4 2.7e-15 55.9 0.9 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 CCM03934.1 - 3e-14 53.4 0.4 4.1e-14 53.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM03934.1 - 2.4e-12 46.8 0.1 8.9e-12 44.9 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM03934.1 - 3.6e-05 23.4 0.0 7e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CCM03934.1 - 0.0044 16.6 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.16 CCM03934.1 - 0.015 14.5 0.3 0.77 8.9 0.1 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family DUF900 PF05990.7 CCM03934.1 - 0.018 14.3 0.1 0.073 12.3 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 CCM03934.1 - 0.024 14.8 0.0 0.065 13.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_3 PF07859.8 CCM03934.1 - 0.04 13.5 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 CCM03934.1 - 0.14 11.6 0.1 0.36 10.3 0.1 1.7 1 1 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.7 CCM03934.1 - 0.18 10.3 1.4 0.32 9.4 0.1 2.0 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Clat_adaptor_s PF01217.15 CCM03935.1 - 2.3e-15 56.5 0.0 4.1e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Metallophos PF00149.23 CCM03935.1 - 1.4e-06 27.8 0.1 2.7e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase N2227 PF07942.7 CCM03936.1 - 6.3e-67 225.3 0.0 8.4e-67 224.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 CCM03936.1 - 2.6e-06 27.2 0.0 6.3e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM03936.1 - 0.0047 17.3 0.0 0.016 15.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM03936.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SH3_1 PF00018.23 CCM03938.1 - 6.5e-11 41.4 0.1 1.3e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCM03938.1 - 4.3e-08 32.6 0.1 1.1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCM03938.1 - 0.00012 21.4 0.0 0.00032 20.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Bac_rhodopsin PF01036.13 CCM03940.1 - 5.7e-38 130.4 18.7 7.6e-38 130.0 12.9 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PsbX PF06596.6 CCM03940.1 - 1.3 8.7 4.1 0.59 9.8 0.6 2.1 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DUF2975 PF11188.3 CCM03941.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) zf-FPG_IleRS PF06827.9 CCM03942.1 - 0.0025 17.4 0.4 0.0049 16.4 0.3 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 CCM03942.1 - 0.0034 17.2 4.3 0.0055 16.6 3.0 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-CHY PF05495.7 CCM03942.1 - 0.0075 16.4 2.9 0.0098 16.0 2.0 1.2 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_2 PF13240.1 CCM03942.1 - 0.012 15.1 2.4 0.08 12.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DRP PF06044.7 CCM03942.1 - 0.023 13.6 0.2 0.023 13.6 0.2 1.1 1 0 0 1 1 1 0 Dam-replacing family zf-RING_3 PF14369.1 CCM03942.1 - 0.026 14.5 2.2 0.06 13.3 1.5 1.7 1 1 0 1 1 1 0 zinc-finger HypA PF01155.14 CCM03942.1 - 0.029 14.0 0.5 0.034 13.8 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 CCM03942.1 - 0.035 14.0 3.7 0.059 13.3 2.6 1.4 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C3HC4_3 PF13920.1 CCM03942.1 - 0.04 13.6 1.2 0.06 13.0 0.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNHCP PF12647.2 CCM03942.1 - 0.09 12.6 0.9 0.12 12.1 0.6 1.2 1 0 0 1 1 1 0 RNHCP domain Zn_Tnp_IS1595 PF12760.2 CCM03942.1 - 0.11 12.3 2.5 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 CCM03942.1 - 0.12 12.1 2.9 0.24 11.2 2.0 1.4 1 1 0 1 1 1 0 Double zinc ribbon LIM PF00412.17 CCM03942.1 - 0.13 12.3 3.2 0.18 11.9 2.2 1.3 1 0 0 1 1 1 0 LIM domain zinc-ribbons_6 PF07191.7 CCM03942.1 - 0.6 9.9 3.3 1.8 8.4 2.3 1.7 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_4 PF13717.1 CCM03942.1 - 0.61 9.8 8.8 3.3 7.4 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CCM03942.1 - 0.69 9.2 4.0 1.6 7.9 2.8 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 CCM03942.1 - 0.83 10.0 6.6 3.9 7.9 1.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zinc_ribbon_5 PF13719.1 CCM03942.1 - 1.2 8.8 8.9 4.2 7.0 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF2197 PF09963.4 CCM03942.1 - 1.2 9.1 5.2 6.5 6.7 1.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) TFIIS_C PF01096.13 CCM03942.1 - 1.2 8.7 3.9 6.2 6.5 0.4 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2 PF00096.21 CCM03942.1 - 1.8 9.0 6.8 1.3 9.5 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cys_rich_KTR PF14205.1 CCM03942.1 - 2.4 7.6 6.3 48 3.5 4.4 2.2 1 1 0 1 1 1 0 Cysteine-rich KTR zf-DNL PF05180.7 CCM03942.1 - 3.3 7.4 7.5 41 3.9 5.2 2.1 1 1 0 1 1 1 0 DNL zinc finger VIT1 PF01988.14 CCM03943.1 - 0.014 14.8 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 VIT family DUF2871 PF11070.3 CCM03943.1 - 0.58 10.3 5.1 2.3 8.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) Ank_3 PF13606.1 CCM03944.1 - 9.5e-14 50.1 0.2 2.7e-05 23.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCM03944.1 - 2.7e-13 49.6 2.1 4.8e-06 26.6 0.3 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCM03944.1 - 4.5e-12 46.1 0.1 9.8e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCM03944.1 - 7.1e-11 41.3 0.9 5.9e-05 22.6 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CCM03944.1 - 2.4e-09 37.4 0.9 0.0002 21.7 0.1 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Neil1-DNA_bind PF09292.5 CCM03944.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind NPIP PF06409.6 CCM03945.1 - 0.0023 16.7 0.0 0.0055 15.4 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore complex interacting protein (NPIP) Mo-nitro_C PF06967.6 CCM03946.1 - 0.092 12.9 1.0 11 6.2 0.1 2.3 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Sperm_act_pep PF08250.6 CCM03946.1 - 2.5 8.5 8.0 9.8 6.7 0.7 2.9 2 0 0 2 2 2 0 Sperm-activating peptides Cwf_Cwc_15 PF04889.7 CCM03947.1 - 1.1e-65 221.7 22.2 1.7e-65 221.1 15.4 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SGT1 PF07093.6 CCM03947.1 - 0.0057 15.0 11.3 0.0061 15.0 7.9 1.1 1 0 0 1 1 1 1 SGT1 protein CDC45 PF02724.9 CCM03947.1 - 0.02 12.9 15.5 0.024 12.7 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 CCM03947.1 - 0.021 14.1 22.2 0.03 13.6 15.4 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 CCM03947.1 - 0.024 12.5 27.4 0.029 12.3 19.0 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 CCM03947.1 - 0.33 10.1 22.4 0.43 9.7 15.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 CCM03947.1 - 3.8 5.8 21.9 4.7 5.5 15.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF506 PF04720.7 CCM03947.1 - 9.2 5.8 11.0 7.1 6.1 6.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF506) Aldedh PF00171.17 CCM03948.1 - 4.9e-118 394.3 4.5 6.1e-118 394.0 3.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_zinc_N_2 PF13602.1 CCM03949.1 - 1.2e-17 64.9 0.0 3.8e-17 63.3 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCM03949.1 - 1.4e-07 31.0 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM03949.1 - 0.0039 16.9 0.0 0.027 14.2 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.19 CCM03950.1 - 9.2e-86 288.1 28.7 1.1e-85 287.9 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM03950.1 - 2.1e-27 95.7 60.7 3.2e-25 88.6 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCM03950.1 - 2.2e-05 23.0 0.8 2.2e-05 23.0 0.5 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein Gate PF07670.9 CCM03950.1 - 1.9 8.4 9.0 6.9 6.6 6.2 2.1 1 1 0 1 1 1 0 Nucleoside recognition DUF1777 PF08648.7 CCM03951.1 - 0.0049 16.6 38.5 0.0049 16.6 26.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) THRAP3_BCLAF1 PF15440.1 CCM03951.1 - 0.0095 14.6 33.7 0.013 14.2 23.4 1.1 1 0 0 1 1 1 1 THRAP3/BCLAF1 family Pox_RNA_pol PF03293.9 CCM03951.1 - 0.089 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit SR-25 PF10500.4 CCM03951.1 - 0.11 11.9 45.0 0.0099 15.3 27.6 1.7 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2413 PF10310.4 CCM03951.1 - 3.2 6.4 13.7 4.8 5.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SOBP PF15279.1 CCM03951.1 - 7.9 6.7 8.4 10 6.4 5.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.17 CCM03951.1 - 8 5.3 11.0 11 4.9 7.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ABC_tran PF00005.22 CCM03952.1 - 1e-47 161.8 0.0 1.5e-28 99.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCM03952.1 - 2.9e-38 131.8 38.6 1.3e-20 74.0 2.9 3.6 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 CCM03952.1 - 2e-11 43.5 5.0 0.0054 15.9 0.3 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCM03952.1 - 3.9e-11 43.4 1.4 0.021 14.8 0.1 4.2 2 2 0 3 3 3 3 AAA domain AAA_25 PF13481.1 CCM03952.1 - 5.3e-08 32.4 0.0 0.0075 15.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 CCM03952.1 - 9.2e-08 32.6 2.6 0.00015 22.1 1.6 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCM03952.1 - 9.5e-07 28.2 0.1 0.052 13.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 CCM03952.1 - 2.4e-05 23.3 0.3 0.015 14.1 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CCM03952.1 - 3.8e-05 23.2 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 CCM03952.1 - 5.2e-05 23.3 5.0 0.046 13.7 0.2 2.9 3 0 0 3 3 2 2 AAA ATPase domain MobB PF03205.9 CCM03952.1 - 8.9e-05 22.2 0.4 0.63 9.7 0.1 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CCM03952.1 - 9.8e-05 22.2 0.2 0.21 11.5 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 CCM03952.1 - 0.0001 22.7 0.0 0.26 11.7 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 CCM03952.1 - 0.00014 22.6 0.0 0.98 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CCM03952.1 - 0.00032 20.4 0.0 0.068 12.8 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 CCM03952.1 - 0.00088 19.4 2.1 0.31 11.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 CCM03952.1 - 0.0012 18.7 1.7 0.079 12.7 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 CCM03952.1 - 0.0015 17.6 0.0 0.97 8.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCM03952.1 - 0.0019 18.5 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CCM03952.1 - 0.002 17.6 2.8 1.5 8.1 0.1 2.8 2 1 1 3 3 3 2 AAA-like domain Adeno_IVa2 PF02456.10 CCM03952.1 - 0.0027 16.4 0.0 0.018 13.6 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein IstB_IS21 PF01695.12 CCM03952.1 - 0.0039 16.6 0.3 3 7.2 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCM03952.1 - 0.0076 15.3 0.1 0.47 9.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DEAD PF00270.24 CCM03952.1 - 0.0078 15.7 0.1 3 7.3 0.1 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 CCM03952.1 - 0.0083 15.7 0.0 0.037 13.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 CCM03952.1 - 0.024 14.4 0.2 2.7 7.7 0.0 2.8 3 0 0 3 3 3 0 Dynamin family ResIII PF04851.10 CCM03952.1 - 0.025 14.4 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 CCM03952.1 - 0.034 13.8 1.0 7.8 6.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 CCM03952.1 - 0.045 13.0 0.6 5.4 6.2 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.17 CCM03952.1 - 0.077 13.1 0.0 21 5.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 CCM03952.1 - 0.083 13.0 1.5 2.3 8.4 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 CCM03952.1 - 0.12 10.9 3.1 4.8 5.6 0.2 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.7 CCM03952.1 - 0.2 11.2 3.2 2.7 7.6 0.0 3.1 3 0 0 3 3 3 0 NACHT domain cobW PF02492.14 CCM03952.1 - 0.4 10.0 3.1 0.98 8.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 CCM03952.1 - 0.47 9.4 0.0 0.9 8.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PQQ_2 PF13360.1 CCM03953.1 - 0.087 12.2 0.0 2.1 7.7 0.0 2.7 2 1 1 3 3 3 0 PQQ-like domain ABC2_membrane PF01061.19 CCM03954.1 - 3e-71 238.9 64.4 2.6e-41 141.1 9.5 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 CCM03954.1 - 1.2e-32 113.0 0.0 2.5e-15 56.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCM03954.1 - 1.7e-29 101.4 13.6 9.9e-28 95.8 0.0 3.6 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CCM03954.1 - 6e-07 29.4 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 CCM03954.1 - 7.8e-07 28.4 0.0 3.7e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCM03954.1 - 8.6e-07 28.5 0.0 0.0069 15.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CCM03954.1 - 7.3e-06 26.1 0.0 0.029 14.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCM03954.1 - 8.2e-06 25.9 0.1 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.2 CCM03954.1 - 2.8e-05 23.3 49.8 0.0026 16.8 14.8 3.6 2 2 1 3 3 3 2 ABC-2 family transporter protein AAA_17 PF13207.1 CCM03954.1 - 0.00036 21.3 0.0 0.11 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCM03954.1 - 0.00044 20.1 0.1 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCM03954.1 - 0.00046 19.8 0.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 CCM03954.1 - 0.00073 19.0 0.2 0.047 13.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCM03954.1 - 0.00087 18.8 0.0 0.078 12.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CCM03954.1 - 0.0031 17.4 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 CCM03954.1 - 0.0051 16.4 0.5 0.42 10.2 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 CCM03954.1 - 0.0054 16.1 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CCM03954.1 - 0.006 16.3 0.5 0.26 11.0 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_21 PF13304.1 CCM03954.1 - 0.0075 16.2 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCM03954.1 - 0.0091 16.3 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CCM03954.1 - 0.011 14.9 0.0 0.15 11.2 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CCM03954.1 - 0.017 14.5 0.1 3.3 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 CCM03954.1 - 0.018 14.5 0.0 1.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 CCM03954.1 - 0.038 13.8 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 CCM03954.1 - 0.058 13.3 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CCM03954.1 - 0.11 12.0 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCM03954.1 - 0.15 12.2 0.0 4.8 7.3 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 CCM03954.1 - 0.27 10.1 0.1 9.3 5.1 0.1 2.2 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 CCM03954.1 - 0.29 11.4 0.0 0.47 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 CCM03954.1 - 0.73 8.8 0.0 4 6.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SNF2_N PF00176.18 CCM03956.1 - 9.1e-46 155.9 0.5 1.5e-44 151.9 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM03956.1 - 4.8e-15 55.1 0.0 1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCM03956.1 - 1.1e-06 27.6 0.0 5.2e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CCM03956.1 - 0.024 14.4 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit YlbD_coat PF14071.1 CCM03956.1 - 0.07 13.1 1.8 0.19 11.8 1.2 1.7 1 0 0 1 1 1 0 Putative coat protein ITAM PF02189.10 CCM03956.1 - 0.13 12.6 0.0 0.42 11.0 0.0 1.9 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif F-box PF00646.28 CCM03957.1 - 6e-05 22.5 0.3 0.00016 21.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCM03957.1 - 8.6e-05 22.1 0.2 0.00018 21.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like Senescence PF06911.7 CCM03958.1 - 2.2e-07 30.7 12.8 9.4e-07 28.6 6.0 2.6 1 1 1 2 2 2 2 Senescence-associated protein Bacteriocin_IIc PF10439.4 CCM03958.1 - 0.027 14.6 11.2 0.68 10.0 1.3 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide AA_permease_2 PF13520.1 CCM03960.1 - 5.3e-66 222.9 46.9 6.4e-66 222.6 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3366 PF11846.3 CCM03960.1 - 1.2 9.0 5.0 0.93 9.3 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) LIM_bind PF01803.11 CCM03961.1 - 1e-53 181.9 0.6 5.9e-53 179.4 0.0 2.4 2 0 0 2 2 2 1 LIM-domain binding protein HMG_box PF00505.14 CCM03962.1 - 1.1e-16 60.8 2.3 1.8e-16 60.1 1.6 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM03962.1 - 2.7e-08 34.0 1.6 4.9e-08 33.2 1.1 1.5 1 0 0 1 1 1 1 HMG-box domain BUD22 PF09073.5 CCM03962.1 - 0.0076 15.3 12.0 0.0093 15.0 8.3 1.2 1 0 0 1 1 1 1 BUD22 YABBY PF04690.8 CCM03962.1 - 0.0097 16.1 0.1 0.0097 16.1 0.1 2.0 2 0 0 2 2 2 1 YABBY protein CDC45 PF02724.9 CCM03962.1 - 0.31 9.0 5.2 0.36 8.7 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.6 CCM03962.1 - 0.65 9.6 4.5 1.1 8.9 3.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) WW PF00397.21 CCM03963.1 - 0.0057 16.4 1.9 0.0057 16.4 1.3 2.4 2 0 0 2 2 2 1 WW domain Yae1_N PF09811.4 CCM03963.1 - 0.03 13.8 0.4 0.065 12.7 0.3 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal DUF2076 PF09849.4 CCM03963.1 - 0.18 11.8 5.3 0.29 11.1 3.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MFS_1 PF07690.11 CCM03964.1 - 5.2e-33 114.2 27.4 8e-33 113.5 19.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CCM03964.1 - 0.0028 17.4 3.0 0.0046 16.7 0.1 2.7 2 0 0 2 2 2 1 MFS_1 like family Glyco_transf_8 PF01501.15 CCM03965.1 - 1.4e-31 109.7 0.0 2.3e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.1 CCM03965.1 - 5.6e-17 62.5 0.1 2.2e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 CCM03965.1 - 0.001 18.2 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Epimerase PF01370.16 CCM03966.1 - 1.3e-42 145.9 0.0 1.8e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM03966.1 - 8.6e-14 50.9 0.0 1.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCM03966.1 - 1.5e-07 30.6 0.0 3.3e-05 22.9 0.0 2.5 2 1 1 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.1 CCM03966.1 - 2e-07 31.2 0.0 3.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CCM03966.1 - 0.00017 20.5 0.0 0.0005 19.0 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 CCM03966.1 - 0.0026 17.0 0.0 0.0057 15.9 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CCM03966.1 - 0.0051 16.7 0.1 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCM03966.1 - 0.019 13.8 0.0 0.28 10.0 0.1 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Glycos_transf_2 PF00535.21 CCM03967.1 - 4.4e-13 49.2 0.1 6.8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCM03967.1 - 1.3e-05 25.0 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CCM03967.1 - 0.003 16.6 0.0 0.0082 15.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 SNF2_N PF00176.18 CCM03968.1 - 4.1e-68 229.3 0.0 6.2e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM03968.1 - 1.2e-11 44.2 0.0 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM03968.1 - 1.7e-07 31.2 0.0 3.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 CCM03968.1 - 8.1e-06 25.5 4.3 8.1e-06 25.5 3.0 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCM03968.1 - 2.5e-05 23.8 5.3 2.5e-05 23.8 3.6 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCM03968.1 - 8.5e-05 22.4 4.3 8.5e-05 22.4 3.0 2.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCM03968.1 - 0.00099 19.1 1.1 0.0026 17.8 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CCM03968.1 - 0.0015 18.1 4.0 0.0015 18.1 2.8 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CCM03968.1 - 0.0025 17.3 3.7 0.0056 16.1 2.5 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CCM03968.1 - 0.012 15.4 3.9 0.012 15.4 2.7 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CCM03968.1 - 0.014 15.2 0.3 0.034 13.9 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 CCM03968.1 - 0.023 14.4 1.1 0.053 13.3 0.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HDA2-3 PF11496.3 CCM03968.1 - 0.037 12.8 0.4 0.25 10.1 0.0 2.4 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 zf-RING_UBOX PF13445.1 CCM03968.1 - 1.4 8.7 5.6 1.1 9.0 2.1 2.3 2 0 0 2 2 1 0 RING-type zinc-finger DEAD_2 PF06733.10 CCM03968.1 - 4.1 6.7 6.6 0.6 9.5 0.1 2.7 3 1 0 3 3 3 0 DEAD_2 PEMT PF04191.8 CCM03969.1 - 3.1e-14 52.9 4.3 3.9e-13 49.4 0.3 3.1 2 1 1 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 CCM03969.1 - 1.9e-12 47.2 0.4 5.1e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 CCM03969.1 - 0.00017 20.2 0.0 0.00041 19.0 0.0 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CCM03969.1 - 0.017 14.4 0.4 0.017 14.4 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Acyl-CoA_dh_1 PF00441.19 CCM03970.1 - 4e-30 104.9 0.3 6.6e-30 104.2 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCM03970.1 - 7.7e-19 66.9 0.3 2.7e-18 65.2 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 CCM03970.1 - 4.3e-17 61.6 0.0 1.6e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 CCM03970.1 - 9e-11 42.3 0.0 2.7e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCM03970.1 - 5.6e-05 23.4 0.1 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain dCMP_cyt_deam_1 PF00383.17 CCM03971.1 - 5.6e-22 77.3 0.3 7.7e-22 76.8 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CCM03971.1 - 0.00024 20.9 3.3 0.014 15.2 2.3 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 CCM03971.1 - 0.0018 17.8 0.0 0.0025 17.4 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Mito_carr PF00153.22 CCM03972.1 - 1.3e-65 217.1 1.0 1.5e-21 75.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S9_N PF02897.10 CCM03973.1 - 1.3e-89 300.6 3.9 1.9e-89 300.1 2.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CCM03973.1 - 2.2e-53 180.6 0.0 5.2e-53 179.4 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family IF3_C PF00707.17 CCM03973.1 - 4.5e-06 26.3 0.1 1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 CCM03973.1 - 4.1e-05 23.0 0.4 9e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Abhydrolase_3 PF07859.8 CCM03973.1 - 0.00069 19.2 0.4 0.0046 16.5 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold HAD_2 PF13419.1 CCM03973.1 - 0.066 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PPR_2 PF13041.1 CCM03974.1 - 2.8e-08 33.5 0.0 0.035 14.0 0.0 4.9 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 CCM03974.1 - 5.6e-05 22.8 6.8 3 8.0 0.0 6.2 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 CCM03974.1 - 0.0004 20.4 10.6 7.4 7.1 0.0 6.5 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCM03974.1 - 0.00094 18.6 0.0 0.28 10.7 0.1 3.4 3 0 0 3 3 3 1 PPR repeat MIF4G_like PF09088.6 CCM03975.1 - 2.1e-58 196.8 0.0 4.1e-58 195.9 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 CCM03975.1 - 3.7e-40 137.7 0.0 5.9e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 CCM03975.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 MIF4G domain UAA PF08449.6 CCM03976.1 - 2.7e-69 233.3 5.3 2.3e-38 131.8 0.1 2.3 2 0 0 2 2 2 2 UAA transporter family TPT PF03151.11 CCM03976.1 - 0.0022 17.6 3.7 0.0032 17.1 0.8 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family Cyclin PF08613.6 CCM03977.1 - 1.6e-13 51.2 0.0 4.4e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCM03977.1 - 1.8e-11 43.7 0.0 2.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SH3_9 PF14604.1 CCM03978.1 - 7.9e-14 50.9 0.2 1.3e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCM03978.1 - 1.3e-13 50.0 0.1 2.5e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCM03978.1 - 2e-11 43.1 0.0 3.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L2_C PF03947.13 CCM03979.1 - 1.4e-42 144.6 1.9 2.2e-42 143.9 1.3 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCM03979.1 - 1.8e-14 53.4 0.0 3.9e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain FGGY_C PF02782.11 CCM03980.1 - 2.6e-47 161.0 1.2 3.9e-47 160.4 0.8 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCM03980.1 - 1.6e-21 76.7 0.1 7.3e-21 74.5 0.0 2.2 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 CCM03980.1 - 5.1e-05 22.7 0.4 0.24 10.6 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family UPF0075 PF03702.9 CCM03980.1 - 0.014 14.3 0.2 0.033 13.0 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0075) FYRC PF05965.9 CCM03980.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 F/Y rich C-terminus MreB_Mbl PF06723.8 CCM03980.1 - 0.083 11.4 0.1 0.22 10.0 0.0 1.7 1 0 0 1 1 1 0 MreB/Mbl protein Cyclin_N PF00134.18 CCM03982.1 - 1.5e-05 24.5 0.1 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCM03982.1 - 5.5e-05 23.6 0.2 9.8e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCM03983.1 - 1.5e-08 34.2 0.3 2.3e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCM03983.1 - 0.00036 20.9 0.2 0.00069 20.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin Ribosomal_S25 PF03297.10 CCM03984.1 - 8.5e-42 141.4 2.2 9.8e-42 141.2 1.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 CCM03984.1 - 0.006 15.9 0.3 0.0095 15.3 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 CCM03984.1 - 0.058 13.1 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 MarR family PRKCSH-like PF12999.2 CCM03985.1 - 3.9e-48 163.3 0.3 1e-47 161.9 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CCM03985.1 - 3.1e-28 98.1 0.0 7.1e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CCM03985.1 - 3.9e-09 37.1 2.7 1.7e-08 35.1 1.9 2.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 CCM03985.1 - 0.16 11.8 11.9 0.24 11.3 0.4 2.6 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF3359 PF11839.3 CCM03985.1 - 0.69 10.2 3.7 0.34 11.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) Cyclin PF08613.6 CCM03987.1 - 1.7e-40 138.8 0.2 1e-39 136.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin WD40 PF00400.27 CCM03988.1 - 5e-08 32.5 1.2 0.36 10.7 0.0 3.7 3 1 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 CCM03989.1 - 3.3e-09 36.2 5.8 1.3e-08 34.3 0.8 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CCM03989.1 - 0.064 11.5 0.0 0.074 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain eIF2A PF08662.6 CCM03989.1 - 0.081 12.6 0.1 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF2454 PF10521.4 CCM03990.1 - 3.6e-29 101.6 0.0 1.6e-28 99.5 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2454) DUF3445 PF11927.3 CCM03992.1 - 1.4e-15 57.3 0.0 1.9e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3445 PF11927.3 CCM03993.1 - 1.8e-12 47.1 0.0 2.4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ADH_zinc_N_2 PF13602.1 CCM03994.1 - 3.3e-05 24.7 0.1 0.0021 18.9 0.1 2.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase GN3L_Grn1 PF08701.6 CCM03995.1 - 6.1e-24 83.7 20.8 6.1e-24 83.7 14.4 2.6 3 1 0 3 3 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 CCM03995.1 - 1.7e-14 53.7 0.4 8.2e-12 45.1 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 CCM03995.1 - 9.6e-08 31.3 0.0 1.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CCM03995.1 - 7.6e-07 29.1 6.1 3.6e-06 26.9 0.4 3.2 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 CCM03995.1 - 1.7e-05 24.0 0.2 2.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Nop14 PF04147.7 CCM03995.1 - 9e-05 20.6 16.2 9e-05 20.6 11.3 2.6 2 1 0 2 2 1 1 Nop14-like family FeoB_N PF02421.13 CCM03995.1 - 0.00022 20.5 0.0 0.0011 18.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 CCM03995.1 - 0.0041 17.6 0.0 0.022 15.2 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Septin PF00735.13 CCM03995.1 - 0.0043 16.1 0.0 0.0089 15.0 0.0 1.4 1 0 0 1 1 1 1 Septin MobB PF03205.9 CCM03995.1 - 0.013 15.1 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 CCM03995.1 - 0.023 13.5 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.5 CCM03995.1 - 0.028 13.6 0.1 0.068 12.3 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Spore_IV_A PF09547.5 CCM03995.1 - 0.053 12.2 0.0 0.43 9.2 0.0 2.0 1 1 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) GBP PF02263.14 CCM03995.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain NAD_binding_10 PF13460.1 CCM03998.1 - 1.6e-06 28.2 0.0 2.8e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding HAD_2 PF13419.1 CCM04000.1 - 3.5e-24 85.9 0.0 8.8e-24 84.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCM04000.1 - 3.8e-05 24.1 0.0 0.0001 22.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AMP-binding PF00501.23 CCM04001.1 - 1.2e-70 238.0 0.0 1.7e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCM04001.1 - 6.7e-67 225.0 0.0 1.2e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CCM04001.1 - 2.7e-12 46.7 0.0 6.9e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CCM04001.1 - 3.4e-10 39.7 0.0 6.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 CCM04001.1 - 1.4e-08 35.5 0.0 5.1e-08 33.7 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 CCM04001.1 - 0.00018 20.3 0.0 0.00066 18.4 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 CCM04001.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 Condensation domain adh_short PF00106.20 CCM04001.1 - 0.057 13.3 0.4 0.73 9.7 0.3 2.4 1 1 0 1 1 1 0 short chain dehydrogenase DEAD PF00270.24 CCM04003.1 - 1.1e-38 132.4 0.0 5.1e-38 130.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM04003.1 - 7.7e-15 54.5 0.1 1.8e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCM04003.1 - 0.00038 19.3 0.0 0.00061 18.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain KH_1 PF00013.24 CCM04004.1 - 1.3e-07 31.0 0.1 6e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 KH domain K_channel_TID PF07941.6 CCM04004.1 - 0.0029 17.8 4.0 0.0068 16.5 2.8 1.6 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain KH_3 PF13014.1 CCM04004.1 - 0.003 17.1 0.9 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 KH domain Trp_repressor PF01371.14 CCM04004.1 - 0.041 13.7 0.1 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Trp repressor protein DUF4160 PF13711.1 CCM04004.1 - 0.11 12.3 0.2 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Mito_fiss_reg PF05308.6 CCM04004.1 - 2.8 7.2 13.3 2.5 7.4 1.0 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator 3Beta_HSD PF01073.14 CCM04005.1 - 6e-31 107.1 0.0 5.9e-30 103.9 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCM04005.1 - 5e-14 52.3 0.0 8.1e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCM04005.1 - 1.7e-13 50.0 0.0 6.9e-10 38.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 CCM04005.1 - 1.9e-07 31.1 0.6 3.9e-06 26.8 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCM04005.1 - 4.6e-06 25.7 0.0 5.9e-05 22.1 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CCM04005.1 - 2.9e-05 24.1 0.0 0.00011 22.2 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CCM04005.1 - 3.2e-05 23.6 0.0 7.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CCM04005.1 - 0.0083 15.0 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain CTP_synth_N PF06418.9 CCM04006.1 - 1e-88 297.0 0.4 2.3e-75 253.2 0.1 2.1 1 1 1 2 2 2 2 CTP synthase N-terminus GATase PF00117.23 CCM04006.1 - 2.1e-48 164.3 0.0 3.1e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCM04006.1 - 0.0073 15.7 0.0 0.038 13.4 0.0 2.1 2 1 0 2 2 2 1 Peptidase C26 ADH_N PF08240.7 CCM04007.1 - 1.5e-29 101.9 1.6 3.6e-29 100.6 1.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM04007.1 - 1.3e-10 40.9 0.0 2.4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 CCM04007.1 - 8.4e-05 21.7 0.4 0.00012 21.2 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N_2 PF13602.1 CCM04007.1 - 0.00023 22.0 0.0 0.001 19.9 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CCM04007.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 CCM04007.1 - 0.0099 15.9 0.1 0.021 14.9 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CCM04007.1 - 0.013 15.8 0.1 0.76 10.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CCM04007.1 - 0.021 15.1 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 CCM04007.1 - 0.045 13.7 0.8 0.2 11.7 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ADH_N_assoc PF13823.1 CCM04007.1 - 0.062 12.9 0.2 0.16 11.6 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 CCM04007.1 - 0.068 13.1 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF2338 PF10100.4 CCM04007.1 - 0.11 10.7 0.0 0.18 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Lgl_C PF08596.5 CCM04007.1 - 0.13 10.7 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal DUF2512 PF10710.4 CCM04008.1 - 0.013 14.9 0.2 0.013 14.9 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2512) TauE PF01925.14 CCM04008.1 - 0.95 8.8 12.0 1.9 7.9 8.3 1.5 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE WD40 PF00400.27 CCM04009.1 - 9e-32 107.8 10.8 2.8e-07 30.1 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat VGCC_beta4Aa_N PF12052.3 CCM04010.1 - 1.6 8.6 6.5 0.17 11.7 0.8 2.1 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal JTB PF05439.7 CCM04012.1 - 0.00026 20.7 0.1 0.00026 20.7 0.1 1.6 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) SRP19 PF01922.12 CCM04013.1 - 1.2e-19 70.6 0.1 3.2e-19 69.2 0.0 1.7 1 1 0 1 1 1 1 SRP19 protein F-box-like PF12937.2 CCM04016.1 - 1.9e-09 37.0 1.2 9.3e-09 34.8 0.4 2.3 2 0 0 2 2 2 1 F-box-like Hexokinase_2 PF03727.11 CCM04017.1 - 1.4e-63 214.3 0.0 1.3e-36 126.0 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 CCM04017.1 - 3.9e-63 212.4 0.0 5.7e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.7 CCM04017.1 - 0.011 15.4 0.1 0.055 13.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Mt_ATP-synt_D PF05873.7 CCM04018.1 - 7.5e-10 38.6 2.4 8.8e-10 38.4 1.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) GAS PF13851.1 CCM04018.1 - 0.0085 15.3 2.3 0.012 14.8 1.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Prominin PF05478.6 CCM04018.1 - 0.024 12.2 0.6 0.026 12.0 0.4 1.0 1 0 0 1 1 1 0 Prominin DUF2408 PF10303.4 CCM04018.1 - 0.086 12.9 0.7 0.13 12.4 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) EF-hand_1 PF00036.27 CCM04019.1 - 1.2e-27 93.0 11.7 3.5e-08 32.1 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCM04019.1 - 2.4e-26 91.6 2.0 2.4e-13 50.0 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CCM04019.1 - 1e-21 75.1 12.4 1.9e-06 26.9 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CCM04019.1 - 3.9e-21 72.9 7.0 3.1e-05 23.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CCM04019.1 - 2.8e-14 52.4 11.8 3.8e-05 23.2 0.6 4.4 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CCM04019.1 - 8.2e-06 25.8 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CCM04019.1 - 2.9e-05 23.7 5.9 0.012 15.3 0.2 3.8 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCM04019.1 - 0.0092 15.8 0.0 1.5 8.7 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain PMBR PF09373.5 CCM04019.1 - 0.073 13.0 0.0 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat TrmE_N PF10396.4 CCM04020.1 - 1.5e-33 115.1 0.0 3.9e-33 113.7 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 CCM04020.1 - 1.1e-19 70.5 0.0 4.4e-19 68.6 0.0 2.1 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 CCM04020.1 - 3.3e-18 65.7 0.0 8.5e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCM04020.1 - 1.8e-06 27.8 0.0 0.00024 20.9 0.0 2.9 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 CCM04020.1 - 0.00028 20.1 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCM04020.1 - 0.0006 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 CCM04020.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCM04020.1 - 0.011 16.5 0.1 0.041 14.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCM04020.1 - 0.036 14.3 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CCM04020.1 - 0.077 12.1 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HEAT_EZ PF13513.1 CCM04020.1 - 0.092 13.2 0.5 1.1 9.8 0.1 2.8 2 0 0 2 2 2 0 HEAT-like repeat QRPTase_C PF01729.14 CCM04020.1 - 0.095 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Adap_comp_sub PF00928.16 CCM04021.1 - 1.9e-51 174.6 0.0 2.2e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCM04021.1 - 0.00029 20.5 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Marek_A PF02124.10 CCM04021.1 - 0.12 11.8 0.0 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 Marek's disease glycoprotein A Sod_Fe_C PF02777.13 CCM04022.1 - 1e-14 54.2 0.2 3.1e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DAD PF02109.11 CCM04023.1 - 1.2e-47 160.6 0.9 1.4e-47 160.4 0.6 1.0 1 0 0 1 1 1 1 DAD family DUF1600 PF07667.6 CCM04023.1 - 0.094 12.8 0.8 0.16 12.0 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) DUF1748 PF08520.5 CCM04024.1 - 1.7e-26 91.6 0.0 1.8e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Isochorismatase PF00857.15 CCM04025.1 - 1.7e-12 47.6 0.0 2.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family TPR_MLP1_2 PF07926.7 CCM04026.1 - 0.06 13.0 8.5 12 5.7 0.0 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cluap1 PF10234.4 CCM04026.1 - 0.91 8.6 6.8 2.1 7.5 4.7 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 CENP-F_leu_zip PF10473.4 CCM04026.1 - 1.1 9.0 21.9 0.17 11.7 0.4 3.4 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 CCM04026.1 - 1.3 9.0 8.7 3.4 7.7 4.6 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 CCM04026.1 - 3.1 7.3 15.0 16 5.0 9.4 2.5 1 1 0 1 1 1 0 IncA protein LRS4 PF10422.4 CCM04026.1 - 3.2 7.0 18.4 0.76 9.0 1.4 4.0 3 0 0 3 3 3 0 Monopolin complex subunit LRS4 Fungal_trans PF04082.13 CCM04027.1 - 2e-14 53.0 0.0 3.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_11 PF13414.1 CCM04028.1 - 1.2e-60 201.0 23.7 1.3e-18 66.4 0.2 6.4 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 CCM04028.1 - 5.4e-50 165.0 20.5 2.3e-07 30.1 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 CCM04028.1 - 1.4e-43 143.2 22.0 8.1e-06 25.3 0.1 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 CCM04028.1 - 2.2e-24 85.5 24.6 1.6e-07 31.7 0.1 7.0 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCM04028.1 - 5e-24 84.0 20.1 1.2e-13 50.7 0.0 6.5 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCM04028.1 - 1.9e-23 80.8 11.2 0.0031 18.0 0.0 9.1 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCM04028.1 - 1.5e-21 76.4 8.6 1.1e-07 32.0 0.0 7.0 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCM04028.1 - 8.7e-20 69.2 9.0 0.0018 18.3 0.1 7.6 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 CCM04028.1 - 1.4e-19 68.2 12.0 0.0023 17.5 0.0 8.2 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 CCM04028.1 - 3.6e-19 67.0 13.9 0.0015 18.1 0.0 8.7 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 CCM04028.1 - 1.4e-10 40.9 8.9 2.4e-05 24.1 0.0 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CCM04028.1 - 1.2e-09 38.2 13.4 0.00022 21.2 0.1 5.5 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCM04028.1 - 5.6e-09 35.8 19.9 1.6 9.3 0.0 9.1 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.1 CCM04028.1 - 5.2e-05 23.0 10.2 0.35 10.8 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat PPR PF01535.15 CCM04028.1 - 0.0002 21.1 0.1 1.1 9.4 0.0 4.8 4 0 0 4 4 4 1 PPR repeat NARP1 PF12569.3 CCM04028.1 - 0.0046 15.7 1.1 0.0046 15.7 0.8 4.0 3 3 2 5 5 5 1 NMDA receptor-regulated protein 1 TPR_3 PF07720.7 CCM04028.1 - 0.035 13.8 16.5 0.17 11.7 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.4 CCM04028.1 - 0.051 12.9 11.0 7.2 5.9 0.6 5.2 3 1 2 5 5 5 0 26S proteasome subunit RPN7 PPR_2 PF13041.1 CCM04028.1 - 0.079 12.9 0.0 3.2 7.7 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family TPR_20 PF14561.1 CCM04028.1 - 0.12 12.4 16.4 12 6.1 0.1 5.5 3 2 2 5 5 5 0 Tetratricopeptide repeat XPC-binding PF09280.6 CCM04028.1 - 0.99 8.9 6.9 1.8 8.0 0.5 2.6 2 0 0 2 2 2 0 XPC-binding domain MIT PF04212.13 CCM04028.1 - 3.7 7.4 16.9 20 5.1 0.1 5.9 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain Aldo_ket_red PF00248.16 CCM04029.1 - 2.6e-39 134.7 0.0 3.1e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nup160 PF11715.3 CCM04030.1 - 1.3e-33 116.0 0.0 2.6e-33 114.9 0.0 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 B12D PF06522.6 CCM04030.1 - 1.2e-13 50.4 2.4 6.2e-13 48.2 0.1 2.8 3 0 0 3 3 3 1 NADH-ubiquinone reductase complex 1 MLRQ subunit TPR_16 PF13432.1 CCM04030.1 - 0.061 14.0 3.1 0.16 12.6 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 CCM04030.1 - 0.073 13.5 1.4 0.97 10.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Cyt-b5 PF00173.23 CCM04032.1 - 5.1e-11 42.2 0.0 1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGS PF00615.14 CCM04033.1 - 2.9e-38 130.5 0.2 7e-38 129.3 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 CCM04033.1 - 5.9e-14 51.5 0.0 8e-07 28.7 0.0 2.9 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.1 CCM04033.1 - 0.047 13.4 0.1 2.6 7.9 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DUF2458 PF10454.4 CCM04035.1 - 1.3e-08 34.8 1.3 1.9e-08 34.3 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.6 CCM04035.1 - 0.017 14.6 0.9 0.025 14.0 0.6 1.2 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Epimerase PF01370.16 CCM04036.1 - 1.1e-42 146.1 0.0 1.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM04036.1 - 1.2e-09 37.2 0.0 1.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CCM04036.1 - 1.7e-09 36.9 0.0 2.3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CCM04036.1 - 6e-09 35.1 0.2 6.3e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 CCM04036.1 - 9.7e-07 27.9 0.1 0.0009 18.2 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CCM04036.1 - 1.4e-05 25.1 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CCM04036.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Bystin PF05291.6 CCM04037.1 - 3.8e-114 380.6 0.0 1.9e-103 345.5 0.0 2.1 2 0 0 2 2 2 2 Bystin PUF PF00806.14 CCM04038.1 - 1.8e-20 71.1 0.0 5.7e-06 25.5 0.0 7.7 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat SAD_SRA PF02182.12 CCM04038.1 - 0.022 14.0 0.1 0.052 12.8 0.1 1.5 1 0 0 1 1 1 0 SAD/SRA domain ATP_bind_3 PF01171.15 CCM04039.1 - 2.6e-18 66.1 0.0 6.6e-18 64.8 0.0 1.7 2 0 0 2 2 2 1 PP-loop family DUF2392 PF10288.4 CCM04039.1 - 0.005 17.1 0.0 0.012 15.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 CCM04039.1 - 0.02 13.4 0.0 0.033 12.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.12 CCM04039.1 - 0.12 11.2 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 NAD synthase DCR PF14047.1 CCM04039.1 - 0.19 12.0 2.2 3.8 7.8 0.0 3.1 3 0 0 3 3 3 0 Dppa2/4 conserved region DUF4428 PF14471.1 CCM04039.1 - 0.92 9.3 4.9 1.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF2616 PF11077.3 CCM04039.1 - 1.5 8.2 7.1 0.95 8.9 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) Na_H_Exchanger PF00999.16 CCM04040.1 - 1.1e-50 172.3 23.2 1.3e-50 172.0 16.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DS PF01916.12 CCM04041.1 - 3.7e-137 456.3 0.0 4.3e-137 456.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Sec7 PF01369.15 CCM04042.1 - 2.8e-66 222.8 0.2 9.8e-66 221.0 0.1 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CCM04042.1 - 1.4e-54 184.0 6.1 5.6e-54 182.0 4.2 2.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCM04042.1 - 3.2e-32 109.9 5.4 4.2e-31 106.3 0.1 4.8 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) HEAT PF02985.17 CCM04042.1 - 0.0037 17.2 0.4 6.6 7.0 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Cas_APE2256 PF09651.5 CCM04042.1 - 0.035 13.8 0.0 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) SH3_1 PF00018.23 CCM04044.1 - 3.4e-38 128.7 6.4 3e-15 55.3 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.1 CCM04044.1 - 4.5e-37 125.3 11.0 2.4e-13 49.4 0.2 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.12 CCM04044.1 - 1.3e-26 91.8 0.1 1.2e-08 34.3 0.0 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 CCM04044.1 - 5.9e-08 32.7 3.8 0.28 11.3 0.1 3.4 3 0 0 3 3 3 3 Bacterial SH3 domain hSH3 PF14603.1 CCM04044.1 - 0.00087 19.2 1.3 1.7 8.6 0.0 3.7 3 1 1 4 4 4 1 Helically-extended SH3 domain GTP_EFTU PF00009.22 CCM04045.1 - 6.3e-48 162.6 0.0 9.8e-48 162.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCM04045.1 - 6e-24 84.0 0.5 2.5e-23 82.0 0.1 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCM04045.1 - 6.2e-11 42.2 0.2 1.9e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCM04045.1 - 0.00038 20.4 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ApoA-II PF04711.8 CCM04045.1 - 0.028 14.3 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) G-alpha PF00503.15 CCM04045.1 - 0.082 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PAM2 PF07145.10 CCM04045.1 - 0.098 12.2 0.2 0.098 12.2 0.1 2.0 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Gtr1_RagA PF04670.7 CCM04045.1 - 0.14 11.2 0.0 0.73 8.9 0.0 2.1 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region DUF3275 PF11679.3 CCM04045.1 - 0.41 10.2 3.4 0.89 9.1 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF605 PF04652.11 CCM04045.1 - 1.5 8.1 13.2 2.4 7.4 9.2 1.3 1 0 0 1 1 1 0 Vta1 like 14-3-3 PF00244.15 CCM04046.1 - 4.6e-74 248.4 3.9 5.2e-74 248.2 2.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Aldo_ket_red PF00248.16 CCM04047.1 - 1.3e-56 191.5 0.0 1.6e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2052 PF09747.4 CCM04048.1 - 3.5e-10 40.0 7.1 5.1e-10 39.5 4.9 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF676 PF05057.9 CCM04049.1 - 5.4e-08 32.3 0.0 9.2e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CCM04049.1 - 8.9e-07 29.0 2.5 1.7e-06 28.0 1.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM04049.1 - 2.7e-05 23.9 2.9 0.00017 21.3 2.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CCM04049.1 - 4.6e-05 23.0 0.0 7.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CCM04049.1 - 0.00058 19.5 0.0 0.0018 17.8 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF915 PF06028.6 CCM04049.1 - 0.0032 16.6 0.0 0.82 8.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 CCM04049.1 - 0.0057 16.2 0.4 0.01 15.4 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 CCM04049.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.3 CCM04049.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF900 PF05990.7 CCM04049.1 - 0.059 12.6 0.0 0.33 10.2 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 CCM04049.1 - 0.085 12.3 0.2 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acetyltransf_1 PF00583.19 CCM04050.1 - 2.7e-14 52.9 0.1 3.6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCM04050.1 - 4.7e-06 26.2 0.1 6.2e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCM04050.1 - 5.2e-06 26.5 0.1 6.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCM04050.1 - 0.00015 21.8 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCM04050.1 - 0.0062 16.7 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCM04050.1 - 0.0094 15.8 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain LRR_4 PF12799.2 CCM04051.1 - 2.1e-16 59.0 5.1 0.078 12.6 0.0 7.5 6 1 0 7 7 7 4 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CCM04051.1 - 8.5e-10 38.2 2.6 8.5e-10 38.2 1.8 2.4 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 CCM04051.1 - 1.4e-07 30.8 14.3 45 4.5 0.0 11.2 12 0 0 12 12 12 0 Leucine Rich repeat LRR_1 PF00560.28 CCM04051.1 - 5.8e-07 28.6 13.5 1.8 8.9 0.1 9.1 9 1 1 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.1 CCM04051.1 - 0.00012 21.6 23.4 2.1 8.1 0.1 7.0 4 2 4 8 8 8 4 Leucine rich repeat Phosphoprotein PF00922.12 CCM04051.1 - 2.8 7.0 6.7 2.4 7.2 3.5 1.6 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein Ste50p-SAM PF09235.5 CCM04051.1 - 4 7.5 14.1 31 4.7 0.0 5.5 5 2 1 6 6 6 0 Ste50p, sterile alpha motif DUF4050 PF13259.1 CCM04052.1 - 0.00039 20.3 0.1 0.00079 19.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) LSM PF01423.17 CCM04053.1 - 9.9e-19 66.6 0.1 1.2e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain zf-U1 PF06220.7 CCM04054.1 - 1.7e-20 72.2 4.1 2.3e-20 71.8 2.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 CCM04054.1 - 0.017 15.2 2.3 0.03 14.4 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Sua5_yciO_yrdC PF01300.13 CCM04055.1 - 3.3e-52 176.3 0.0 6.6e-52 175.3 0.0 1.5 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 CCM04055.1 - 1.1e-26 93.4 0.0 2.1e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.24 CCM04056.1 - 6.5e-36 123.3 0.0 1.2e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM04056.1 - 3.5e-23 81.2 0.0 7e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM04056.1 - 0.023 14.5 0.2 0.057 13.2 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Mob1_phocein PF03637.12 CCM04058.1 - 7.6e-73 243.8 0.0 8.8e-73 243.6 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DJ-1_PfpI PF01965.19 CCM04059.1 - 7.8e-22 77.3 0.1 1e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 CCM04059.1 - 6.2e-11 41.6 0.1 6.2e-11 41.6 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family RRM_1 PF00076.17 CCM04060.1 - 1.5e-17 62.9 0.1 2e-07 30.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04060.1 - 1.4e-12 47.3 0.0 2.8e-05 24.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM04060.1 - 3.5e-12 45.9 0.0 1.1e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim54 PF11711.3 CCM04060.1 - 0.0014 17.2 0.4 0.002 16.8 0.2 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 CCM04060.1 - 0.04 11.8 4.2 0.045 11.6 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 CCM04060.1 - 1.3 8.6 3.9 2.9 7.5 2.7 1.6 1 0 0 1 1 1 0 FAM176 family TRAM_LAG1_CLN8 PF03798.11 CCM04061.1 - 4.4e-40 137.3 25.9 5.7e-40 136.9 18.0 1.1 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 CCM04061.1 - 2.4e-09 36.5 2.9 3.1e-08 32.9 0.0 3.3 3 0 0 3 3 3 1 TRAM1-like protein Snf7 PF03357.16 CCM04062.1 - 7.7e-35 119.7 14.3 7.7e-35 119.7 9.9 1.3 2 0 0 2 2 2 1 Snf7 Heme_oxygenase PF01126.15 CCM04062.1 - 0.0057 16.2 0.5 0.0098 15.4 0.4 1.4 1 0 0 1 1 1 1 Heme oxygenase DUF3135 PF11333.3 CCM04062.1 - 0.13 12.4 3.5 3.3 7.9 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3135) TraF_2 PF13729.1 CCM04062.1 - 0.47 9.2 7.2 2.5 6.8 0.4 2.2 1 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein DUF29 PF01724.11 CCM04062.1 - 0.97 9.2 6.5 0.096 12.5 0.6 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 RNA_pol_Rpb1_5 PF04998.12 CCM04062.1 - 1 8.5 5.8 1.2 8.3 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Rapamycin_bind PF08771.6 CCM04062.1 - 1 9.4 4.9 1.3 9.1 0.3 2.5 1 1 2 3 3 3 0 Rapamycin binding domain Atg14 PF10186.4 CCM04062.1 - 1.4 7.8 15.5 2.2 7.1 10.1 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3138 PF11336.3 CCM04062.1 - 2.8 5.9 7.7 3.2 5.8 4.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DUF342 PF03961.8 CCM04062.1 - 3 6.1 12.3 4.2 5.6 7.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Viral_P18 PF04521.8 CCM04062.1 - 4.5 6.7 10.6 3.8 6.9 3.3 2.5 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ribosomal_L6e PF01159.14 CCM04062.1 - 6.1 7.1 8.0 21 5.4 2.3 2.4 1 1 1 2 2 2 0 Ribosomal protein L6e Macoilin PF09726.4 CCM04062.1 - 6.7 4.8 17.9 6.9 4.8 11.5 1.5 1 1 1 2 2 2 0 Transmembrane protein NIF PF03031.13 CCM04063.1 - 2.4e-49 167.0 0.0 3.3e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_hydro_2 PF00703.16 CCM04064.1 - 7e-08 32.9 0.0 1.7e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 CCM04064.1 - 4.3e-05 23.1 0.1 8.3e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 CCM04064.1 - 8.7e-05 21.5 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF2563 PF10817.3 CCM04064.1 - 0.067 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) Ras PF00071.17 CCM04065.1 - 1.6e-46 157.6 0.5 1.9e-46 157.4 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM04065.1 - 1.6e-14 54.4 0.5 2.5e-14 53.7 0.2 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCM04065.1 - 1.6e-07 30.7 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM04065.1 - 2.6e-06 26.9 0.5 1.2e-05 24.8 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCM04065.1 - 8.3e-05 22.5 0.0 0.00011 22.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCM04065.1 - 0.0063 15.7 0.1 0.0074 15.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CCM04065.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCM04065.1 - 0.014 15.1 0.1 0.015 15.0 0.1 1.4 1 1 0 1 1 1 0 Archaeal ATPase Spo12 PF05032.7 CCM04066.1 - 2.1e-08 33.6 3.9 3.4e-08 32.9 2.7 1.3 1 0 0 1 1 1 1 Spo12 family PCNP PF15473.1 CCM04066.1 - 3.3 8.0 8.8 5.1 7.3 5.9 1.6 1 1 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family Chitin_synth_1 PF01644.12 CCM04067.1 - 1.4e-61 207.0 0.1 2.1e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCM04067.1 - 2.7e-28 97.4 0.2 5.1e-28 96.5 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCM04067.1 - 4.9e-24 84.6 1.0 3.1e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CCM04067.1 - 2.9e-11 43.4 6.3 3.3e-10 39.9 4.3 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCM04067.1 - 2.2e-07 30.9 0.0 7.1e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Terpene_synth_C PF03936.11 CCM04069.1 - 2.3e-18 66.4 0.1 3.5e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 CCM04071.1 - 2.5e-18 66.2 0.2 3.6e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 CCM04072.1 - 3.2e-62 210.5 0.0 4.3e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 CCM04074.1 - 0.0021 18.0 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF829 PF05705.9 CCM04076.1 - 6.2e-34 117.7 0.0 1.6e-33 116.4 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Acyl-CoA_dh_M PF02770.14 CCM04077.1 - 0.0009 18.7 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain p450 PF00067.17 CCM04078.1 - 6.1e-63 212.9 0.0 1.6e-45 155.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 CCM04080.1 - 2e-36 125.4 56.5 2e-36 125.4 39.2 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCM04080.1 - 5e-22 77.8 24.7 8.3e-22 77.1 17.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCM04080.1 - 3.9e-15 55.3 17.7 3.9e-15 55.3 12.3 3.2 1 1 1 3 3 3 2 Sugar (and other) transporter adh_short PF00106.20 CCM04082.1 - 1.6e-24 86.6 0.1 2.9e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM04082.1 - 3.7e-14 53.0 0.0 4.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM04082.1 - 3.4e-07 30.0 0.1 7.5e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCM04082.1 - 5.4e-06 26.5 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 CCM04082.1 - 0.00027 20.1 0.0 0.0012 18.1 0.0 2.0 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 CCM04082.1 - 0.0027 17.1 0.0 0.0045 16.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CCM04082.1 - 0.023 13.6 0.0 0.057 12.2 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain rve_3 PF13683.1 CCM04082.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DUF3328 PF11807.3 CCM04083.1 - 1.9e-17 63.6 0.8 2.2e-17 63.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Coq4 PF05019.8 CCM04084.1 - 1.9e-57 193.7 0.0 1.6e-28 99.1 0.0 2.1 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Chitin_synth_1 PF01644.12 CCM04085.1 - 1.3e-67 226.6 0.0 2.2e-67 225.9 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCM04085.1 - 3e-26 90.9 0.0 9.6e-26 89.2 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCM04085.1 - 6.5e-24 84.1 3.6 3.7e-16 58.6 0.1 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 CCM04085.1 - 1.8e-06 27.8 0.0 6.3e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Xpo1 PF08389.7 CCM04086.1 - 6.3e-12 45.6 0.1 1.2e-09 38.2 0.0 4.0 4 1 1 5 5 5 1 Exportin 1-like protein CRM1_C PF08767.6 CCM04086.1 - 0.0072 15.2 0.1 0.016 14.1 0.0 1.7 2 0 0 2 2 2 1 CRM1 C terminal IBN_N PF03810.14 CCM04086.1 - 0.033 14.0 0.0 0.76 9.7 0.0 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain MMS22L_C PF14911.1 CCM04086.1 - 0.11 11.5 0.0 3.4 6.6 0.1 2.9 3 0 0 3 3 3 0 S-phase genomic integrity recombination mediator, C-terminal Adaptin_N PF01602.15 CCM04086.1 - 0.28 9.4 0.0 3.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region LRR19-TM PF15176.1 CCM04087.1 - 0.14 11.9 0.1 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2613 PF11021.3 CCM04087.1 - 1.5 8.5 5.4 5.9 6.6 3.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) ATP_synt_I PF03899.10 CCM04088.1 - 0.096 12.8 9.3 0.74 10.0 0.3 3.2 3 0 0 3 3 3 0 ATP synthase I chain EMP70 PF02990.11 CCM04088.1 - 0.35 9.2 8.2 0.71 8.2 5.7 1.5 1 1 0 1 1 1 0 Endomembrane protein 70 MFS_1 PF07690.11 CCM04088.1 - 0.54 8.9 10.8 4 6.0 6.8 2.1 1 1 0 1 1 1 0 Major Facilitator Superfamily HUN PF08729.5 CCM04089.1 - 4.4e-11 42.4 0.6 1.1e-10 41.1 0.4 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 CCM04089.1 - 4.5e-06 26.5 0.0 0.0056 16.3 0.0 2.4 2 0 0 2 2 2 2 Ubinuclein conserved middle domain DNA_pol_lambd_f PF10391.4 CCM04091.1 - 1.3e-18 66.2 0.1 7e-17 60.7 0.1 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 CCM04091.1 - 6e-18 64.7 0.0 6.5e-17 61.4 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.1 CCM04091.1 - 1.3e-16 60.5 0.0 9.7e-16 57.8 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_5 PF14520.1 CCM04091.1 - 0.0011 19.1 0.1 0.02 15.0 0.0 2.5 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.18 CCM04091.1 - 0.0033 17.0 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif NTP_transf_2 PF01909.18 CCM04091.1 - 0.018 15.3 0.0 0.049 13.9 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain Pol_alpha_B_N PF08418.5 CCM04091.1 - 3.7 7.0 7.6 3.5 7.0 0.0 2.9 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal Methyltransf_23 PF13489.1 CCM04092.1 - 4.1e-08 33.0 0.0 8.2e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM04092.1 - 2.1e-07 30.6 0.0 7e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM04092.1 - 2.2e-07 31.2 0.0 4.2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM04092.1 - 0.00011 21.4 0.0 0.00075 18.6 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CCM04092.1 - 0.00028 21.2 0.0 0.00071 19.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM04092.1 - 0.0007 20.0 0.0 0.0029 18.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCM04092.1 - 0.0011 18.0 0.0 0.0045 16.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.11 CCM04092.1 - 0.0063 14.9 0.0 0.0089 14.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.14 CCM04092.1 - 0.018 15.0 0.1 0.055 13.4 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CCM04092.1 - 0.026 15.0 0.0 0.33 11.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 CCM04092.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Peptidase_M16 PF00675.15 CCM04093.1 - 1.8e-18 66.7 0.1 2.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCM04093.1 - 0.012 15.2 0.0 0.1 12.2 0.0 2.3 1 1 0 1 1 1 0 Peptidase M16 inactive domain PLA2_B PF01735.13 CCM04094.1 - 3.2e-89 299.3 0.0 4.4e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF4470 PF14737.1 CCM04095.1 - 7.6e-23 80.1 0.0 1.4e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 CCM04095.1 - 1.5e-10 40.7 13.7 3.2e-10 39.7 9.5 1.6 1 0 0 1 1 1 1 MYND finger FMO-like PF00743.14 CCM04096.1 - 5.9e-24 84.1 0.0 9.5e-24 83.4 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCM04096.1 - 1.5e-22 80.6 0.0 1e-21 77.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM04096.1 - 3.6e-11 42.5 0.0 1.3e-08 34.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM04096.1 - 5.9e-09 36.0 0.0 2.8e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCM04096.1 - 4e-05 23.7 0.0 0.003 17.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CCM04096.1 - 0.00018 21.8 0.0 0.35 11.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCM04096.1 - 0.00041 20.1 0.5 0.23 11.2 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding TrkA_N PF02254.13 CCM04096.1 - 0.0039 17.1 0.1 0.067 13.2 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain CPSase_L_chain PF00289.17 CCM04096.1 - 0.0041 17.1 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain AlaDh_PNT_C PF01262.16 CCM04096.1 - 0.008 15.7 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CCM04096.1 - 0.013 15.1 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCM04096.1 - 0.017 14.2 1.5 0.38 9.8 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 CCM04096.1 - 0.026 13.4 0.0 0.63 8.8 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CCM04096.1 - 0.073 13.3 0.0 5.8 7.2 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 CCM04096.1 - 0.12 11.1 0.0 1.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CCM04096.1 - 0.13 11.3 0.0 0.3 10.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 CCM04096.1 - 0.13 10.6 0.0 0.41 9.0 0.0 1.8 3 0 0 3 3 3 0 HI0933-like protein Velvet PF11754.3 CCM04097.1 - 2.5e-43 148.0 0.3 1.1e-42 145.9 0.2 2.0 1 1 0 1 1 1 1 Velvet factor Pyr_redox_3 PF13738.1 CCM04098.1 - 2.8e-19 69.9 0.0 5.4e-18 65.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM04098.1 - 5.6e-10 39.0 2.5 9.3e-07 28.7 0.1 3.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CCM04098.1 - 7.8e-08 31.6 0.0 3.8e-06 26.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 CCM04098.1 - 1.4e-07 30.1 0.0 2.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CCM04098.1 - 5.8e-07 29.5 0.1 0.021 14.6 0.1 3.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM04098.1 - 1.2e-06 28.8 0.1 0.0088 16.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM04098.1 - 1.6e-06 27.2 0.2 0.0053 15.7 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 CCM04098.1 - 7.1e-06 25.2 0.2 0.00043 19.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 CCM04098.1 - 1.4e-05 24.9 1.0 0.25 11.0 0.1 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CCM04098.1 - 3.3e-05 23.1 0.2 0.00071 18.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 CCM04098.1 - 0.00011 22.3 0.0 0.079 13.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 CCM04098.1 - 0.00014 21.0 0.0 1.6 7.7 0.0 3.2 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 CCM04098.1 - 0.00071 18.5 0.0 0.16 10.8 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCM04098.1 - 0.00085 18.2 0.2 0.00085 18.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 CCM04098.1 - 0.0019 17.6 0.9 0.036 13.4 0.1 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 CCM04098.1 - 0.0032 17.7 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 CCM04098.1 - 0.013 13.9 1.8 0.018 13.5 0.1 2.0 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 CCM04098.1 - 0.017 13.8 2.4 1.3 7.5 0.1 3.0 3 0 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.16 CCM04098.1 - 0.018 14.8 0.9 0.068 12.9 0.0 2.1 2 0 0 2 2 2 0 ThiF family NAD_Gly3P_dh_N PF01210.18 CCM04098.1 - 0.053 13.2 0.6 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 CCM04098.1 - 0.089 11.6 0.7 5.4 5.7 0.1 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A F420_oxidored PF03807.12 CCM04098.1 - 0.089 13.2 0.4 24 5.4 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 CCM04098.1 - 0.13 12.2 0.4 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain ACOX PF01756.14 CCM04099.1 - 1.1e-18 67.2 0.0 1.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CCM04099.1 - 5.3e-12 46.1 0.0 8.5e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CCM04099.1 - 3.3e-07 29.7 0.8 9.4e-07 28.2 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CCM04099.1 - 1e-06 28.9 0.6 2.3e-06 27.8 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CHZ PF09649.5 CCM04100.1 - 5.3e-10 38.3 0.2 5.3e-10 38.3 0.1 2.9 3 0 0 3 3 3 1 Histone chaperone domain CHZ DUF2890 PF11081.3 CCM04100.1 - 0.0022 18.0 3.4 0.0022 18.0 2.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2890) La PF05383.12 CCM04101.1 - 3.3e-11 42.7 0.0 6.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CCM04101.1 - 3.5e-06 26.5 0.1 8.3e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04101.1 - 5.4e-05 23.0 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCM04101.1 - 0.00028 20.7 0.0 0.00062 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif AMP-binding PF00501.23 CCM04102.1 - 3.2e-87 292.6 0.0 4.4e-87 292.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCM04102.1 - 0.092 13.7 0.1 0.45 11.5 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain PLDc_N PF13396.1 CCM04104.1 - 0.032 13.8 0.2 0.032 13.8 0.1 3.1 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal Pkinase_Tyr PF07714.12 CCM04105.1 - 6.3e-37 127.0 0.0 1.3e-36 125.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM04105.1 - 3.5e-36 124.7 0.0 4.5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RicinB_lectin_2 PF14200.1 CCM04105.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Abhydrolase_6 PF12697.2 CCM04106.1 - 8.4e-28 97.7 0.0 9.9e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM04106.1 - 1.2e-17 64.2 0.0 3e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM04106.1 - 9.3e-08 31.9 0.0 4.4e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CCM04106.1 - 0.0025 18.1 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 CCM04106.1 - 0.029 14.2 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S15 PF02129.13 CCM04106.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AA_permease_2 PF13520.1 CCM04107.1 - 6.9e-57 192.8 38.9 9.1e-57 192.4 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCM04107.1 - 5.8e-17 61.1 31.5 9.1e-17 60.5 21.8 1.2 1 0 0 1 1 1 1 Amino acid permease Fanconi_A PF03511.9 CCM04107.1 - 0.056 13.2 0.1 4.9 6.9 0.1 2.9 2 0 0 2 2 2 0 Fanconi anaemia group A protein DUF2207 PF09972.4 CCM04107.1 - 1.1 7.7 5.4 3.6 6.0 1.8 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) AA_permease_2 PF13520.1 CCM04108.1 - 4.9e-47 160.4 33.7 8.4e-47 159.6 23.4 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCM04108.1 - 7.7e-09 34.4 31.7 0.00014 20.3 15.5 2.1 2 0 0 2 2 2 2 Amino acid permease Orai-1 PF07856.7 CCM04108.1 - 0.044 13.3 1.1 0.074 12.6 0.0 1.9 2 0 0 2 2 2 0 Mediator of CRAC channel activity GST_C_2 PF13410.1 CCM04109.1 - 2.2e-05 24.2 0.1 3.7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCM04109.1 - 6.3e-05 23.1 0.1 0.00012 22.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM04109.1 - 0.0098 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GPI-anchored PF10342.4 CCM04110.1 - 3.4e-13 49.8 7.0 3.4e-13 49.8 4.9 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF515 PF04415.7 CCM04110.1 - 6.1 4.9 5.9 7 4.7 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) G-alpha PF00503.15 CCM04111.1 - 4.4e-122 407.5 0.0 5.1e-122 407.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCM04111.1 - 1.3e-10 40.7 0.6 2.1e-06 27.0 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCM04111.1 - 0.00028 20.1 0.0 0.3 10.1 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CCM04111.1 - 0.0032 16.9 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CCM04111.1 - 0.055 12.5 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin GTP_EFTU PF00009.22 CCM04111.1 - 0.061 12.7 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 CCM04111.1 - 0.063 13.7 0.0 0.32 11.4 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 CCM04111.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RAP1 PF07218.6 CCM04112.1 - 1.2 7.1 10.2 2 6.3 7.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Na_H_Exchanger PF00999.16 CCM04113.1 - 5.5e-67 225.9 36.2 6.8e-67 225.6 25.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF202 PF02656.10 CCM04114.1 - 0.04 14.1 2.2 0.072 13.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pyr_redox_3 PF13738.1 CCM04115.1 - 1.2e-14 54.9 0.0 2.4e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM04115.1 - 2.5e-07 29.9 0.1 1.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM04115.1 - 4.5e-05 23.4 0.0 0.024 14.5 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCM04115.1 - 0.00035 20.3 0.4 0.28 10.9 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF202 PF02656.10 CCM04116.1 - 0.18 12.0 6.0 1.7 8.8 4.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) FA_desaturase PF00487.19 CCM04116.1 - 1.1 8.6 7.5 2.4 7.5 5.2 1.5 1 1 0 1 1 1 0 Fatty acid desaturase 60KD_IMP PF02096.15 CCM04117.1 - 3.7e-29 101.7 8.6 5.3e-29 101.3 5.9 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein BING4CT PF08149.6 CCM04118.1 - 3.6e-24 84.0 0.0 1.1e-23 82.5 0.0 1.7 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 CCM04118.1 - 6.4e-09 35.3 0.1 1.6e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 CCM04118.1 - 0.0036 15.5 0.0 0.0038 15.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 OPT PF03169.10 CCM04119.1 - 1.5e-119 400.1 37.7 1.7e-119 400.0 26.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Myosin_tail_1 PF01576.14 CCM04120.1 - 0.00056 17.7 13.8 0.00056 17.7 9.5 7.2 2 2 2 7 7 7 4 Myosin tail Spc7 PF08317.6 CCM04120.1 - 1.2 7.6 115.5 0.0045 15.7 4.7 8.6 3 1 6 9 9 9 0 Spc7 kinetochore protein WD40_alt PF14077.1 CCM04120.1 - 1.3 8.6 8.2 5.5 6.7 0.1 5.4 4 0 0 4 4 4 0 Alternative WD40 repeat motif Reo_sigmaC PF04582.7 CCM04120.1 - 6.5 5.8 70.4 1.3 8.1 6.1 8.3 2 2 4 8 8 8 0 Reovirus sigma C capsid protein HSBP1 PF06825.7 CCM04120.1 - 8.2 6.0 14.3 1.2 8.7 0.2 4.7 5 0 0 5 5 5 0 Heat shock factor binding protein 1 OGFr_N PF04664.8 CCM04122.1 - 6.9e-38 130.1 0.1 1.1e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region DUF727 PF05303.7 CCM04123.1 - 1.6e-05 24.6 0.0 1.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Sec1 PF00995.18 CCM04124.1 - 1.6e-134 449.6 0.0 1.9e-134 449.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family IncA PF04156.9 CCM04125.1 - 0.01 15.4 19.0 0.01 15.4 13.2 4.4 1 1 3 4 4 4 0 IncA protein Tropomyosin_1 PF12718.2 CCM04125.1 - 0.011 15.6 10.4 0.011 15.6 7.2 4.6 1 1 4 5 5 5 0 Tropomyosin like Reo_sigmaC PF04582.7 CCM04125.1 - 0.025 13.7 26.3 0.072 12.2 1.1 3.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Fez1 PF06818.10 CCM04125.1 - 0.11 12.4 59.1 0.052 13.5 3.1 3.6 1 1 1 3 3 3 0 Fez1 Spc7 PF08317.6 CCM04125.1 - 0.32 9.6 45.5 0.19 10.3 8.4 3.7 1 1 2 3 3 3 0 Spc7 kinetochore protein WEMBL PF05701.6 CCM04125.1 - 1.5 7.2 76.7 6.1 5.1 30.4 2.3 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 CCM04125.1 - 2 6.0 73.1 0.18 9.5 16.3 4.0 1 1 2 4 4 4 0 Myosin tail DUF4201 PF13870.1 CCM04125.1 - 3.1 7.2 41.5 0.058 12.8 6.3 5.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4201) Filament PF00038.16 CCM04125.1 - 3.2 7.1 59.7 0.021 14.2 8.7 4.6 1 1 3 4 4 4 0 Intermediate filament protein ATG16 PF08614.6 CCM04125.1 - 3.3 7.4 60.6 4.2 7.1 5.5 4.4 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) COPIIcoated_ERV PF07970.7 CCM04126.1 - 1e-68 231.3 2.7 1.8e-68 230.4 1.3 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCM04126.1 - 2.5e-31 107.4 0.2 2.5e-31 107.4 0.2 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3672 PF12421.3 CCM04126.1 - 0.11 12.6 0.2 0.32 11.1 0.1 1.9 1 1 0 1 1 1 0 Fibronectin type III protein Nitroreductase PF00881.19 CCM04128.1 - 9.1e-14 51.6 0.0 1.1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Filament PF00038.16 CCM04129.1 - 0.002 17.6 25.7 0.0021 17.6 5.9 2.2 1 1 1 2 2 2 2 Intermediate filament protein MCC-bdg_PDZ PF10506.4 CCM04129.1 - 0.026 14.3 2.0 0.026 14.3 1.4 2.9 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Reo_sigmaC PF04582.7 CCM04129.1 - 0.43 9.6 5.2 0.46 9.6 2.4 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CCM04129.1 - 1.3 7.3 20.2 0.1 11.0 10.3 1.5 1 1 0 1 1 1 0 AAA domain PspB PF06667.7 CCM04130.1 - 0.5 10.3 4.0 10 6.1 0.5 2.6 2 0 0 2 2 2 0 Phage shock protein B Pinin_SDK_memA PF04696.8 CCM04130.1 - 1.1 8.8 12.8 1.6 8.3 0.5 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region p450 PF00067.17 CCM04133.1 - 1.4e-22 79.9 0.0 1.6e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Noc2 PF03715.8 CCM04134.1 - 9.9e-50 169.0 3.2 1.5e-49 168.4 0.1 2.6 4 0 0 4 4 4 1 Noc2p family rve PF00665.21 CCM04134.1 - 0.00093 19.3 0.0 0.0039 17.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Peptidase_C37 PF05416.7 CCM04134.1 - 1.3 7.1 6.3 2.6 6.2 4.3 1.4 1 0 0 1 1 1 0 Southampton virus-type processing peptidase SNF2_N PF00176.18 CCM04135.1 - 1.4e-38 132.3 0.0 3.9e-38 130.9 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM04135.1 - 2.1e-09 37.0 0.0 5.3e-06 26.2 0.0 3.4 2 1 1 3 3 3 2 Helicase conserved C-terminal domain VIGSSK PF14773.1 CCM04135.1 - 1.3e-05 24.9 0.1 4.3e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal AAA_14 PF13173.1 CCM04135.1 - 0.092 12.6 0.0 2.6 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain tRNA-synt_1 PF00133.17 CCM04136.1 - 5.8e-40 136.8 0.0 1.3e-30 106.0 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CCM04136.1 - 5.1e-16 58.3 0.0 7.6e-09 34.7 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCM04136.1 - 1.1e-15 57.7 0.0 2.6e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CCM04136.1 - 7.9e-08 31.7 0.0 1.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain HMG_box PF00505.14 CCM04137.1 - 2.9e-24 85.0 1.7 2.9e-24 85.0 1.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM04137.1 - 4.2e-19 68.6 2.3 4.2e-19 68.6 1.6 1.7 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.7 CCM04137.1 - 0.00044 19.8 0.0 0.00076 19.1 0.0 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.8 CCM04137.1 - 0.00056 20.1 1.4 0.00063 20.0 0.6 1.4 1 1 0 1 1 1 1 YABBY protein HMG_box_5 PF14887.1 CCM04137.1 - 0.0093 15.7 4.0 0.0093 15.7 2.8 2.0 1 1 1 2 2 2 1 HMG (high mobility group) box 5 Hc1 PF07432.8 CCM04137.1 - 3.6 7.7 13.7 0.9 9.7 5.1 2.1 2 0 0 2 2 2 0 Histone H1-like protein Hc1 Oxysterol_BP PF01237.13 CCM04138.1 - 8.4e-75 251.4 0.5 2.9e-74 249.6 0.3 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein Peptidase_C65 PF10275.4 CCM04139.1 - 7.3e-67 225.2 0.0 8.1e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 CCM04139.1 - 0.00012 22.6 0.0 0.27 11.8 0.0 2.4 2 0 0 2 2 2 2 OTU-like cysteine protease Aminotran_4 PF01063.14 CCM04140.1 - 4.1e-17 62.4 0.0 6.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV PseudoU_synth_1 PF01416.15 CCM04141.1 - 1.8e-24 86.1 0.0 1.3e-14 54.5 0.0 3.3 2 2 0 2 2 2 2 tRNA pseudouridine synthase BAALC_N PF06989.7 CCM04141.1 - 0.1 12.9 0.1 0.1 12.9 0.0 2.4 3 0 0 3 3 3 0 BAALC N-terminus SurE PF01975.12 CCM04142.1 - 1.3e-36 125.7 0.1 1.8e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE CHB_HEX_C_1 PF13290.1 CCM04142.1 - 0.055 13.2 0.5 0.15 11.9 0.4 1.7 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Cerato-platanin PF07249.7 CCM04143.1 - 6.8e-29 100.2 3.3 8.6e-29 99.9 2.3 1.1 1 0 0 1 1 1 1 Cerato-platanin SurE PF01975.12 CCM04144.1 - 1.2e-28 99.7 0.2 1.8e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE p450 PF00067.17 CCM04145.1 - 2.7e-63 214.1 0.0 4e-63 213.5 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 HSP20 PF00011.16 CCM04146.1 - 4.3e-23 81.0 0.1 5.9e-23 80.6 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 CCM04146.1 - 0.012 15.4 0.2 0.31 10.8 0.1 2.3 2 0 0 2 2 2 0 BON domain p450 PF00067.17 CCM04147.1 - 5.7e-77 259.1 0.0 9.1e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM04148.1 - 2.8e-36 125.0 0.0 3.3e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_11 PF13414.1 CCM04149.1 - 1.1e-19 69.8 19.6 7.2e-05 22.3 0.0 7.6 7 1 0 7 7 7 5 TPR repeat TPR_16 PF13432.1 CCM04149.1 - 2e-13 50.5 22.9 0.00019 21.9 0.1 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCM04149.1 - 2e-11 42.9 24.0 0.0025 17.6 0.6 9.8 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCM04149.1 - 3.7e-11 43.2 19.5 0.0024 18.1 0.1 7.4 8 1 1 9 9 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCM04149.1 - 2.2e-10 40.2 24.7 2.4 9.0 0.0 10.3 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCM04149.1 - 1.7e-09 36.7 6.6 0.51 10.2 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCM04149.1 - 3.8e-09 36.0 4.7 0.017 15.2 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCM04149.1 - 3.2e-08 32.8 14.6 0.2 11.3 0.1 8.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCM04149.1 - 4.8e-08 32.8 33.1 0.00054 19.8 0.6 8.3 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCM04149.1 - 2.1e-07 30.2 21.7 0.098 12.5 0.0 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 CCM04149.1 - 1.2e-05 25.3 10.2 6.7 6.9 0.2 6.3 6 2 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.1 CCM04149.1 - 4.3e-05 23.7 3.1 0.14 12.4 0.1 3.4 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation TPR_20 PF14561.1 CCM04149.1 - 0.00028 20.9 6.6 0.92 9.6 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCM04149.1 - 0.0023 18.2 13.2 8.3 7.1 0.2 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat UPF0253 PF06786.7 CCM04149.1 - 0.068 13.2 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) TPR_9 PF13371.1 CCM04149.1 - 0.13 12.1 13.5 0.25 11.2 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCM04149.1 - 1.6 8.7 17.3 27 4.8 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat p450 PF00067.17 CCM04150.1 - 8.6e-77 258.6 0.0 1.4e-76 257.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SICA_C PF12879.2 CCM04150.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain DUF1212 PF06738.7 CCM04151.1 - 5.2e-26 91.2 3.2 5.2e-26 91.2 2.2 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CCM04151.1 - 6.7e-17 61.6 10.9 6.7e-17 61.6 7.6 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3815) Gti1_Pac2 PF09729.4 CCM04152.1 - 1.8e-26 92.9 8.9 2e-23 83.0 0.4 3.0 2 1 1 3 3 3 2 Gti1/Pac2 family MutL_C PF08676.6 CCM04153.1 - 4.5e-19 68.4 0.1 2.3e-18 66.1 0.0 2.1 3 0 0 3 3 3 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CCM04153.1 - 5.1e-16 58.1 0.0 9.4e-16 57.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCM04153.1 - 2.4e-12 46.6 0.0 5.1e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCM04153.1 - 1.1e-11 44.4 0.2 2.9e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-MYND PF01753.13 CCM04154.1 - 5.1e-11 42.2 15.9 9.8e-11 41.3 11.0 1.5 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.2 CCM04154.1 - 4.3e-09 36.6 0.0 1.3e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCM04154.1 - 5.8e-06 26.0 0.1 0.023 14.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 CCM04154.1 - 2.1e-05 24.0 0.1 0.096 12.5 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCM04154.1 - 0.0011 19.1 0.3 0.041 14.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCM04154.1 - 0.0081 16.6 0.0 0.19 12.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2039 PF10217.4 CCM04154.1 - 0.012 15.6 3.8 0.021 14.8 2.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-HIT PF04438.11 CCM04154.1 - 9.8 5.9 15.0 5 6.8 7.7 2.5 2 1 0 2 2 2 0 HIT zinc finger Methyltransf_22 PF13383.1 CCM04155.1 - 5.8e-26 91.5 0.0 9.3e-26 90.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 CCM04155.1 - 4.1e-08 33.3 0.0 1.2e-07 31.8 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase FkbM domain Pkinase_Tyr PF07714.12 CCM04156.1 - 1.4e-51 175.0 0.0 2.8e-51 174.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM04156.1 - 1.1e-44 152.5 0.0 1.8e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCM04156.1 - 0.0017 18.1 0.2 0.0076 16.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCM04156.1 - 0.0039 16.2 0.0 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CK2S PF15011.1 CCM04156.1 - 0.031 14.0 0.1 0.093 12.5 0.0 1.8 2 0 0 2 2 2 0 Casein Kinase 2 substrate ATXN-1_C PF12547.3 CCM04157.1 - 0.13 12.2 6.9 0.031 14.2 1.8 2.2 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator DUF4239 PF14023.1 CCM04158.1 - 0.0036 16.6 0.4 0.0074 15.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) TLD PF07534.11 CCM04159.1 - 4.2e-28 98.0 0.0 9.7e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 TLD DUF3433 PF11915.3 CCM04159.1 - 4e-27 94.2 5.6 6.8e-17 61.4 0.8 3.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) IncA PF04156.9 CCM04161.1 - 0.07 12.7 0.2 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 IncA protein DUF3338 PF11819.3 CCM04161.1 - 0.079 12.4 0.4 0.16 11.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) KdpC PF02669.10 CCM04161.1 - 0.086 12.5 0.7 0.28 10.8 0.5 1.8 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Leu_zip PF15294.1 CCM04161.1 - 0.1 11.6 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Leucine zipper Peptidase_S64 PF08192.6 CCM04161.1 - 0.28 9.4 0.3 0.43 8.8 0.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF904 PF06005.7 CCM04161.1 - 0.3 11.4 1.3 0.5 10.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Zip PF02535.17 CCM04164.1 - 8.9e-39 133.3 7.8 1e-38 133.1 5.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.17 CCM04165.1 - 6.1e-51 173.3 8.1 8e-51 172.9 5.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 CCM04165.1 - 0.85 8.7 4.1 0.17 11.0 0.2 1.7 2 0 0 2 2 2 0 UNC-50 family Glyco_hydro_47 PF01532.15 CCM04166.1 - 1.8e-128 429.0 0.0 2.1e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2781 PF10914.3 CCM04167.1 - 1.9e-35 121.8 10.7 2.3e-35 121.5 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) 7tm_1 PF00001.16 CCM04167.1 - 0.0062 15.6 0.5 0.01 15.0 0.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2628 PF10947.3 CCM04167.1 - 1.1 9.1 6.0 2.4 8.0 4.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) WD40 PF00400.27 CCM04168.1 - 6e-12 44.9 0.4 0.0016 18.2 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat CPSF_A PF03178.10 CCM04168.1 - 0.0012 18.0 0.0 0.0095 15.0 0.0 2.2 2 1 0 2 2 2 1 CPSF A subunit region Cys_Met_Meta_PP PF01053.15 CCM04169.1 - 2.9e-53 180.5 0.0 1e-50 172.1 0.0 2.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_47 PF01532.15 CCM04172.1 - 5.5e-135 450.5 0.0 6.3e-135 450.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.8 CCM04173.1 - 7.3e-30 102.7 0.1 1.7e-29 101.5 0.1 1.6 2 0 0 2 2 2 1 Erv1 / Alr family NmrA PF05368.8 CCM04174.1 - 1.8e-33 115.7 0.0 2.3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CCM04174.1 - 1.5e-09 38.0 0.7 3.3e-09 37.0 0.5 1.6 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 CCM04174.1 - 0.00043 20.1 0.5 0.0009 19.1 0.4 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 CCM04174.1 - 0.00055 19.6 0.4 0.00097 18.8 0.3 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 CCM04174.1 - 0.018 15.3 0.4 0.029 14.6 0.3 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CCM04174.1 - 0.058 12.0 0.7 0.17 10.5 0.4 1.8 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCM04174.1 - 0.081 12.3 0.8 0.17 11.2 0.1 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CCM04174.1 - 0.38 10.6 2.9 3.9 7.3 2.0 2.1 1 1 0 1 1 1 0 short chain dehydrogenase SH3_1 PF00018.23 CCM04175.1 - 2.9e-10 39.3 0.0 4.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCM04175.1 - 8.3e-08 31.6 0.0 1.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CCM04175.1 - 9.5e-08 31.5 0.0 1.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.8 CCM04175.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Phage_holin_1 PF04531.8 CCM04175.1 - 0.54 10.3 4.6 45 4.2 2.4 3.0 3 0 0 3 3 3 0 Bacteriophage holin ABC2_membrane_5 PF13346.1 CCM04175.1 - 4.1 6.6 15.3 6 6.0 10.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein adh_short PF00106.20 CCM04176.1 - 1.4e-28 99.9 2.5 2.1e-28 99.3 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04176.1 - 1.2e-13 51.1 0.9 1.8e-13 50.5 0.6 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCM04176.1 - 0.00031 20.4 0.1 0.038 13.7 0.1 2.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 CCM04176.1 - 0.0058 15.5 0.0 0.0088 14.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 CCM04176.1 - 0.0091 15.4 0.1 0.017 14.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 CCM04176.1 - 0.02 13.9 0.1 0.066 12.2 0.1 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 CCM04176.1 - 0.063 12.4 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 CCM04177.1 - 2.8e-29 102.1 2.3 4e-29 101.6 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04177.1 - 2.5e-12 46.8 0.9 3.7e-12 46.2 0.7 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCM04177.1 - 3.4e-05 23.5 2.8 0.0042 16.8 1.7 2.6 2 1 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 CCM04177.1 - 0.0033 16.3 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF2244 PF10003.4 CCM04177.1 - 0.021 14.1 0.0 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) THF_DHG_CYH_C PF02882.14 CCM04177.1 - 0.022 13.8 0.1 0.047 12.7 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 CCM04177.1 - 0.058 12.8 0.1 0.091 12.1 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PA PF02225.17 CCM04177.1 - 0.096 12.3 0.6 0.2 11.3 0.4 1.5 1 0 0 1 1 1 0 PA domain NmrA PF05368.8 CCM04178.1 - 9.7e-35 119.9 0.0 1.3e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CCM04178.1 - 6.1e-11 42.6 1.6 1e-10 41.8 1.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 CCM04178.1 - 3.8e-06 26.1 0.1 5.1e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 CCM04178.1 - 0.00017 21.2 0.2 0.0003 20.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 CCM04178.1 - 0.00018 21.4 0.1 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 CCM04178.1 - 0.0088 16.0 0.2 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 CCM04178.1 - 0.014 15.3 0.5 0.027 14.4 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DXP_reductoisom PF02670.11 CCM04178.1 - 0.018 15.6 0.1 0.048 14.1 0.1 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 CCM04178.1 - 0.034 14.4 0.2 0.065 13.5 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CCM04178.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CCM04178.1 - 0.17 12.3 3.7 15 6.1 2.6 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Paf1 PF03985.8 CCM04179.1 - 8.2e-61 206.0 0.0 1e-60 205.7 0.0 1.0 1 0 0 1 1 1 1 Paf1 CRAL_TRIO PF00650.15 CCM04180.1 - 6.2e-29 100.5 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCM04180.1 - 4.2e-05 23.5 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Histone PF00125.19 CCM04181.1 - 5.7e-30 103.2 0.7 9.4e-30 102.5 0.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCM04181.1 - 2.3e-05 24.5 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCM04181.1 - 0.0045 17.0 1.2 0.0055 16.7 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CCM04181.1 - 0.0095 15.2 0.9 0.0098 15.1 0.6 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCM04181.1 - 0.08 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CCM04182.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCM04182.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CCM04182.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CCM04182.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CCM04182.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CCM04182.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit F-box-like PF12937.2 CCM04183.1 - 0.00083 19.0 0.0 0.0022 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like RhoGAP PF00620.22 CCM04184.1 - 2.2e-44 150.7 0.0 4.2e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 CCM04184.1 - 8.5e-17 61.1 1.7 2e-16 59.9 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Baculo_PEP_C PF04513.7 CCM04184.1 - 0.14 11.9 0.6 11 5.8 0.0 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_16 PF10294.4 CCM04185.1 - 3.6e-26 91.6 0.0 5e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CCM04185.1 - 0.0061 16.3 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rhomboid PF01694.17 CCM04186.1 - 2.2e-13 50.4 18.2 3e-12 46.7 12.6 2.6 1 1 0 1 1 1 1 Rhomboid family RNase_T PF00929.19 CCM04187.1 - 5.7e-09 36.4 0.0 1.4e-08 35.2 0.0 1.6 2 0 0 2 2 2 1 Exonuclease Cas1_AcylT PF07779.7 CCM04188.1 - 2.4e-158 527.6 21.1 2.5e-157 524.2 14.6 2.0 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF605 PF04652.11 CCM04188.1 - 3.2e-73 247.3 18.7 1.6e-37 129.8 12.7 2.8 2 1 0 2 2 2 2 Vta1 like PC-Esterase PF13839.1 CCM04188.1 - 4.3e-29 102.1 0.0 7.1e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p adh_short_C2 PF13561.1 CCM04189.1 - 1.8e-25 90.1 0.0 2.1e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCM04189.1 - 1.5e-23 83.5 0.0 1.9e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04189.1 - 9.6e-10 38.4 0.0 1.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCM04189.1 - 0.00059 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 CCM04189.1 - 0.0037 16.4 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Arrestin_C PF02752.17 CCM04190.1 - 7.5e-12 45.5 0.0 4.8e-11 42.9 0.0 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCM04190.1 - 0.095 12.5 0.0 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain FR47 PF08445.5 CCM04191.1 - 2.3e-07 30.4 0.0 4.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 CCM04191.1 - 4.3e-07 29.8 0.0 8.6e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCM04191.1 - 1e-06 28.8 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCM04191.1 - 2.2e-05 24.5 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCM04191.1 - 0.0027 17.6 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCM04191.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCM04191.1 - 0.044 13.9 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNase_P_pop3 PF08228.6 CCM04192.1 - 1.8e-14 53.8 0.0 5.7e-12 45.7 0.0 2.6 2 1 0 2 2 2 2 RNase P subunit Pop3 HEAT_2 PF13646.1 CCM04193.1 - 0.0038 17.4 2.7 0.42 10.9 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 CCM04193.1 - 0.0054 17.1 2.0 4 8.0 0.1 3.6 2 0 0 2 2 2 2 HEAT-like repeat HEAT PF02985.17 CCM04193.1 - 0.61 10.3 7.6 2 8.7 0.0 4.7 6 0 0 6 6 6 0 HEAT repeat Chorismate_bind PF00425.13 CCM04194.1 - 2.5e-66 223.6 0.0 5.2e-66 222.6 0.0 1.5 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 CCM04194.1 - 6.5e-37 126.8 0.0 8.9e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CCM04194.1 - 2.1e-17 63.4 0.0 5.4e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CCM04194.1 - 3e-05 23.5 0.3 9.9e-05 21.8 0.2 1.8 1 1 0 1 1 1 1 Peptidase C26 2OG-FeII_Oxy PF03171.15 CCM04195.1 - 0.0013 19.0 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CCM04195.1 - 0.067 13.7 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal UQ_con PF00179.21 CCM04196.1 - 1.5e-39 134.6 0.1 1.8e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CCM04196.1 - 0.0028 17.3 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 CCM04196.1 - 0.014 15.2 0.3 0.018 14.9 0.2 1.3 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 CCM04196.1 - 0.054 13.2 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_6 PF14259.1 CCM04197.1 - 7.7e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCM04197.1 - 1.1e-07 31.4 0.0 6.8e-07 28.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM04197.1 - 0.001 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 CCM04197.1 - 1.2 7.1 5.2 1.2 7.1 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.7 CCM04197.1 - 9.2 5.1 8.3 15 4.4 5.7 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Syntaxin PF00804.20 CCM04198.1 - 3.5e-16 59.2 3.7 3.5e-16 59.2 2.5 3.0 3 1 0 3 3 2 1 Syntaxin SNARE PF05739.14 CCM04198.1 - 2.2e-14 52.8 0.9 2.2e-14 52.8 0.6 3.4 3 1 1 4 4 4 1 SNARE domain Syntaxin-18_N PF10496.4 CCM04198.1 - 0.00066 19.4 4.1 0.017 14.9 0.1 3.5 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Sed5p PF11416.3 CCM04198.1 - 0.0014 18.0 0.2 0.0053 16.1 0.1 2.1 1 0 0 1 1 1 1 Integral membrane protein Sed5p zf-C4H2 PF10146.4 CCM04198.1 - 0.0045 17.0 2.1 0.49 10.3 0.1 2.2 2 0 0 2 2 2 2 Zinc finger-containing protein Cluap1 PF10234.4 CCM04198.1 - 0.061 12.5 10.3 0.044 13.0 1.9 2.4 2 1 0 2 2 2 0 Clusterin-associated protein-1 BLOC1_2 PF10046.4 CCM04198.1 - 0.38 10.9 8.3 2 8.6 0.5 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 CCM04198.1 - 0.45 10.3 8.8 1.5 8.6 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Osmo_CC PF08946.5 CCM04198.1 - 0.47 10.5 4.5 1.1 9.3 0.2 3.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil NPV_P10 PF05531.7 CCM04198.1 - 0.75 10.0 10.5 0.34 11.1 1.1 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.16 CCM04198.1 - 3.8 7.8 8.6 0.52 10.6 0.3 2.8 3 1 0 3 3 3 0 Spectrin repeat SlyX PF04102.7 CCM04198.1 - 4.7 7.6 8.9 3.4 8.0 0.7 3.2 3 0 0 3 3 3 0 SlyX Phage_GPL PF05926.6 CCM04198.1 - 7.6 6.3 7.7 0.42 10.4 0.4 2.4 3 2 0 3 3 3 0 Phage head completion protein (GPL) IncA PF04156.9 CCM04198.1 - 8.5 5.9 14.2 3.7 7.1 0.9 2.5 2 1 0 2 2 2 0 IncA protein NAD_Gly3P_dh_C PF07479.9 CCM04199.1 - 5.3e-48 162.5 0.3 8.1e-48 161.9 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 CCM04199.1 - 1.2e-32 112.7 0.0 1.9e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 CCM04199.1 - 3.2e-06 27.4 0.0 1.3e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CCM04199.1 - 5.9e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 CCM04199.1 - 0.00087 19.2 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.10 CCM04199.1 - 0.0037 17.1 0.0 0.0097 15.7 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 CCM04199.1 - 0.13 12.2 0.0 0.81 9.6 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding Ank_2 PF12796.2 CCM04200.1 - 3.8e-09 36.7 0.0 7.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCM04200.1 - 1.4e-08 34.0 0.0 7.7e-06 25.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CCM04200.1 - 1.5e-06 28.5 0.0 3.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCM04200.1 - 1.1e-05 25.4 0.0 3.8e-05 23.7 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM04200.1 - 1.3e-05 24.9 0.0 0.018 15.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat zf-CCCH_2 PF14608.1 CCM04200.1 - 0.00013 21.8 4.4 0.00013 21.8 3.1 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CCM04200.1 - 0.00038 20.0 10.3 0.04 13.6 1.4 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GARS_A PF01071.14 CCM04201.1 - 2.9e-78 261.9 0.0 4e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CCM04201.1 - 2.1e-34 117.9 0.0 6.3e-34 116.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 CCM04201.1 - 3.3e-30 105.1 0.0 6.5e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 CCM04201.1 - 1e-27 96.0 0.1 2.7e-27 94.7 0.1 1.8 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 CCM04201.1 - 4.3e-18 65.3 0.7 2e-17 63.2 0.3 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 CCM04201.1 - 2.3e-09 37.2 0.0 6.2e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCM04201.1 - 1.2e-07 30.8 0.0 2.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 CCM04201.1 - 4.8e-05 22.7 0.0 8.7e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 CCM04201.1 - 0.0073 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCM04201.1 - 0.038 13.3 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CCM04201.1 - 0.19 11.5 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP11 PF06644.6 CCM04202.1 - 0.055 12.9 0.4 0.1 12.0 0.3 1.4 1 0 0 1 1 1 0 ATP11 protein Pal1 PF08316.6 CCM04202.1 - 0.14 12.5 0.0 0.14 12.5 0.0 3.1 3 1 0 3 3 3 0 Pal1 cell morphology protein MRP-S25 PF13741.1 CCM04204.1 - 2.5e-48 164.5 0.3 4.2e-48 163.8 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 CCM04204.1 - 0.029 14.2 5.8 0.54 10.1 3.1 2.6 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 PCI PF01399.22 CCM04205.1 - 2.2e-17 63.2 0.0 7.4e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_20 PF14561.1 CCM04205.1 - 0.055 13.5 0.5 0.21 11.7 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Drc1-Sld2 PF11719.3 CCM04206.1 - 5.3e-14 52.1 2.4 5.3e-14 52.1 1.7 2.5 1 1 1 2 2 2 1 DNA replication and checkpoint protein Pal1 PF08316.6 CCM04207.1 - 0.037 14.4 0.9 0.093 13.1 0.0 2.2 2 0 0 2 2 2 0 Pal1 cell morphology protein zf-met PF12874.2 CCM04208.1 - 1.6e-06 28.0 1.2 3e-06 27.2 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 CCM04208.1 - 0.018 14.3 0.6 0.034 13.4 0.4 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like S1 PF00575.18 CCM04209.1 - 4e-52 174.2 20.9 1.5e-11 44.2 0.0 10.5 10 0 0 10 10 10 8 S1 RNA binding domain TPR_12 PF13424.1 CCM04209.1 - 5.1e-07 29.5 1.0 0.02 14.7 0.0 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM04209.1 - 8.9e-07 29.4 0.0 0.017 15.8 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM04209.1 - 2.8e-06 27.4 0.0 0.021 15.3 0.0 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCM04209.1 - 3e-06 27.4 0.0 0.045 14.0 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCM04209.1 - 0.00011 21.4 1.6 0.049 12.6 0.1 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCM04209.1 - 0.0013 18.5 0.8 4.9 7.3 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat EXOSC1 PF10447.4 CCM04209.1 - 0.0021 17.9 0.2 1.6 8.7 0.0 4.3 3 0 0 3 3 3 1 Exosome component EXOSC1/CSL4 TPR_21 PF09976.4 CCM04209.1 - 0.0028 17.5 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCM04209.1 - 0.0093 15.5 0.0 0.19 11.4 0.0 2.6 1 1 2 3 3 3 2 TPR repeat TPR_7 PF13176.1 CCM04209.1 - 0.018 14.8 0.3 0.12 12.2 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCM04209.1 - 0.039 14.4 0.1 8.7 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCM04209.1 - 0.15 12.3 0.0 78 3.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCM04209.1 - 0.26 10.9 0.0 7.8 6.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Kelch_3 PF13415.1 CCM04210.1 - 1e-38 130.6 13.6 1.6e-07 31.2 0.0 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CCM04210.1 - 1.2e-34 117.7 4.1 3.8e-09 36.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 CCM04210.1 - 1.1e-32 111.5 16.7 1.8e-08 34.0 0.0 7.3 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CCM04210.1 - 4e-28 96.3 5.4 2.9e-07 30.3 0.3 6.5 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 CCM04210.1 - 5.6e-24 82.9 7.0 2.4e-05 23.9 0.2 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CCM04210.1 - 8.4e-23 79.6 1.3 3.8e-06 26.3 0.5 6.0 6 0 0 6 6 6 4 Kelch motif WEMBL PF05701.6 CCM04210.1 - 0.00078 18.0 25.2 0.00078 18.0 17.5 3.7 2 1 1 3 3 3 1 Weak chloroplast movement under blue light RabGAP-TBC PF00566.13 CCM04212.1 - 5.2e-48 163.3 0.0 7.9e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M4 PF01447.13 CCM04212.1 - 0.065 13.3 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain COX6B PF02297.12 CCM04213.1 - 1e-21 76.6 1.2 1.4e-21 76.3 0.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 CCM04213.1 - 0.033 14.2 0.3 0.043 13.8 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Aldedh PF00171.17 CCM04215.1 - 4e-85 285.8 0.0 4.7e-85 285.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LRR_4 PF12799.2 CCM04216.1 - 0.81 9.3 2.9 2.4 7.8 0.0 3.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) BCS1_N PF08740.6 CCM04217.1 - 5e-45 153.4 2.5 6.7e-45 153.0 1.7 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CCM04217.1 - 2.1e-17 63.5 0.0 4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCM04217.1 - 5.5e-05 23.9 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCM04217.1 - 0.00012 21.9 0.0 0.00072 19.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCM04217.1 - 0.0002 20.7 0.0 0.00043 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCM04217.1 - 0.0014 18.1 0.0 0.0038 16.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CCM04217.1 - 0.0029 17.6 0.1 0.012 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CCM04217.1 - 0.0037 16.2 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 CCM04217.1 - 0.0096 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCM04217.1 - 0.011 15.4 0.0 0.037 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CCM04217.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCM04217.1 - 0.021 14.5 0.0 0.076 12.7 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CCM04217.1 - 0.022 14.9 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCM04217.1 - 0.03 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 CCM04217.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 CCM04217.1 - 0.067 13.1 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CCM04217.1 - 0.097 12.1 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 CCM04217.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MBOAT PF03062.14 CCM04219.1 - 4.2e-27 95.1 23.5 1.3e-25 90.2 9.7 2.6 1 1 1 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family CK_II_beta PF01214.13 CCM04220.1 - 1.8e-71 239.4 0.0 2.1e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Arrestin_N PF00339.24 CCM04221.1 - 0.003 17.3 0.0 0.0076 16.0 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain TPR_11 PF13414.1 CCM04222.1 - 6.4e-14 51.3 8.3 1.5e-09 37.3 4.9 2.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 CCM04222.1 - 1e-12 47.0 6.1 3.1e-05 23.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCM04222.1 - 2.1e-11 42.8 6.7 0.00013 21.5 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM04222.1 - 5.5e-09 36.4 9.2 3.6e-06 27.5 3.8 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCM04222.1 - 1.6e-08 34.7 8.7 2.4e-07 31.0 2.0 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM04222.1 - 6.6e-08 32.5 9.1 0.0011 19.3 0.1 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCM04222.1 - 0.00015 22.0 1.9 0.37 11.3 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCM04222.1 - 0.00033 20.2 4.7 0.014 15.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCM04222.1 - 0.00043 20.1 7.1 0.042 13.7 3.2 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCM04222.1 - 0.0017 17.9 1.0 2.1 8.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCM04222.1 - 0.0024 17.7 2.9 1.2 9.0 0.6 3.5 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 CCM04222.1 - 0.02 14.8 3.2 0.46 10.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCM04222.1 - 0.033 14.0 6.6 0.046 13.5 1.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCM04222.1 - 8.5 6.8 7.9 13 6.2 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Metallophos PF00149.23 CCM04223.1 - 1.2e-08 34.6 0.4 4.6e-08 32.7 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCM04223.1 - 1.7e-06 27.9 0.0 3.7e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HSP20 PF00011.16 CCM04224.1 - 1.8e-05 24.5 0.1 3.5e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Muted PF14942.1 CCM04224.1 - 1.1 9.1 8.9 2.5 7.9 6.2 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein UvrD_C PF13361.1 CCM04225.1 - 3.1e-73 247.2 0.0 7.4e-73 246.0 0.0 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCM04225.1 - 2.5e-64 217.5 0.0 4.1e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 CCM04225.1 - 1.3e-15 56.9 0.1 7e-14 51.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 CCM04225.1 - 1.1e-12 48.0 0.0 4.3e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 CCM04225.1 - 6.2e-06 25.9 0.0 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CCM04225.1 - 1.6e-05 24.5 3.4 0.072 12.5 0.0 3.6 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 CCM04225.1 - 0.004 16.5 0.0 0.041 13.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain Sugar_tr PF00083.19 CCM04226.1 - 5.7e-117 391.0 27.0 8.7e-117 390.4 18.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM04226.1 - 2.8e-25 88.7 46.4 8.3e-19 67.5 12.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C14 PF00656.17 CCM04227.1 - 9e-68 228.6 0.0 1.1e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Abhydrolase_1 PF00561.15 CCM04229.1 - 0.023 14.2 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCM04229.1 - 0.09 12.6 0.0 0.09 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family SAM_PNT PF02198.11 CCM04231.1 - 0.00093 18.9 0.1 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Cupin_2 PF07883.6 CCM04232.1 - 2.6e-27 94.0 0.6 1.2e-12 47.1 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CCM04232.1 - 1.9e-26 92.2 0.0 3.4e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 CCM04232.1 - 5.8e-09 35.2 0.1 0.00027 20.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 CCM04232.1 - 6.2e-05 22.6 0.1 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 CCM04232.1 - 0.00024 20.7 0.0 0.0037 16.8 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 CCM04232.1 - 0.0058 16.0 0.0 0.039 13.3 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 CCM04232.1 - 0.066 13.1 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family Cupin_4 PF08007.7 CCM04232.1 - 0.086 12.0 0.1 0.62 9.2 0.0 1.9 2 0 0 2 2 2 0 Cupin superfamily protein Pirin_C PF05726.8 CCM04232.1 - 0.087 12.9 0.0 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Pirin C-terminal cupin domain GPI PF06560.6 CCM04232.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) UCH PF00443.24 CCM04233.1 - 2.3e-31 108.9 0.0 3e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM04233.1 - 1.9e-14 53.8 0.0 2.8e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CCM04233.1 - 0.039 13.2 1.3 0.94 8.7 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Atrophin-1 PF03154.10 CCM04233.1 - 6 4.8 6.4 9.1 4.2 4.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family CDC45 PF02724.9 CCM04234.1 - 7.1 4.5 7.7 9.3 4.1 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Thg1C PF14413.1 CCM04235.1 - 2.7e-46 156.1 0.0 4.2e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 CCM04235.1 - 2.6e-24 85.3 0.0 3.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Pterin_4a PF01329.14 CCM04236.1 - 0.0027 17.4 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PSCyt3 PF07627.6 CCM04236.1 - 0.031 14.1 1.6 0.085 12.7 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) Fork_head PF00250.13 CCM04237.1 - 1.1e-27 95.8 0.2 2.1e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Fork head domain NAD_binding_4 PF07993.7 CCM04238.1 - 1.6e-28 99.3 0.0 5.2e-28 97.6 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 CCM04238.1 - 6.5e-26 90.6 0.0 1.5e-25 89.4 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 CCM04238.1 - 3.4e-06 26.6 0.0 6.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CCM04238.1 - 0.0018 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site FAM117 PF15388.1 CCM04238.1 - 0.23 10.6 0.0 0.43 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein Family FAM117 Cerato-platanin PF07249.7 CCM04239.1 - 8.4e-52 174.2 6.4 1.1e-25 89.9 1.4 2.1 2 0 0 2 2 2 2 Cerato-platanin SOG2 PF10428.4 CCM04240.1 - 4.7 5.7 8.5 6 5.4 5.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.20 CCM04241.1 - 1.2e-34 119.6 0.0 1.6e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM04241.1 - 4e-12 45.7 0.0 5.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DSBA PF01323.15 CCM04242.1 - 2.5e-31 108.7 0.0 3.3e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 CCM04242.1 - 3e-09 37.1 0.2 1.1e-08 35.2 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.1 CCM04242.1 - 0.0004 20.0 0.3 0.0007 19.2 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCM04242.1 - 0.0093 16.1 0.0 3.8 7.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 CCM04242.1 - 0.027 14.2 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain AAA_10 PF12846.2 CCM04242.1 - 0.074 12.4 0.1 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Frag1 PF10277.4 CCM04243.1 - 1.1e-37 129.5 20.3 1.3e-37 129.3 14.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2207 PF09972.4 CCM04243.1 - 0.008 14.8 1.2 0.008 14.8 0.8 2.9 1 1 2 3 3 3 1 Predicted membrane protein (DUF2207) Kinocilin PF15033.1 CCM04243.1 - 0.2 11.2 4.3 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Kinocilin protein Vps51 PF08700.6 CCM04244.1 - 1.9e-23 82.0 1.6 2.5e-23 81.6 1.1 1.2 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 CCM04244.1 - 0.0013 17.2 1.3 0.0018 16.8 0.9 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 CCM04244.1 - 0.003 17.5 1.9 0.0044 16.9 1.3 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 FlgN PF05130.7 CCM04244.1 - 0.0064 16.7 2.2 0.0094 16.2 1.6 1.2 1 0 0 1 1 1 1 FlgN protein Aldedh PF00171.17 CCM04245.1 - 8e-112 373.9 0.4 1e-111 373.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCM04245.1 - 4e-06 25.7 0.1 3.5e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) DUF427 PF04248.7 CCM04246.1 - 1.2e-36 124.2 0.1 1.8e-29 101.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Epimerase PF01370.16 CCM04248.1 - 3.3e-23 82.3 0.2 4.5e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM04248.1 - 1.5e-15 56.6 0.0 2.5e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCM04248.1 - 5.3e-15 55.8 0.4 1.2e-14 54.7 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCM04248.1 - 2.5e-12 46.2 0.1 9.7e-12 44.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CCM04248.1 - 4.1e-07 29.4 0.1 6.1e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CCM04248.1 - 5.7e-07 29.5 1.0 6.2e-06 26.2 0.2 2.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCM04248.1 - 0.0013 17.7 0.1 0.0017 17.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CCM04248.1 - 0.0029 17.2 0.4 0.032 13.9 0.2 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM04249.1 - 4.9e-23 81.7 0.1 7.6e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM04249.1 - 9.2e-16 57.3 0.0 2.4e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCM04249.1 - 7.6e-12 45.6 1.0 1.5e-11 44.6 0.7 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCM04249.1 - 1.3e-10 40.6 0.1 1.2e-09 37.4 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CCM04249.1 - 1.2e-05 24.4 0.2 2.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CCM04249.1 - 2e-05 23.9 0.4 3.9e-05 23.0 0.2 1.6 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 CCM04249.1 - 0.0011 17.8 0.1 1.3 7.8 0.0 2.5 2 1 0 2 2 2 2 RmlD substrate binding domain Methyltransf_26 PF13659.1 CCM04249.1 - 0.012 15.6 0.2 0.028 14.4 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 CCM04249.1 - 0.012 15.4 2.3 0.086 12.7 1.2 2.4 1 1 1 2 2 2 0 short chain dehydrogenase KR PF08659.5 CCM04249.1 - 0.029 14.0 1.1 0.36 10.4 0.8 2.2 1 1 0 1 1 1 0 KR domain Epimerase PF01370.16 CCM04250.1 - 5e-26 91.5 0.0 6.6e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM04250.1 - 3.3e-19 68.6 0.0 4.5e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCM04250.1 - 2.1e-15 57.1 0.0 3.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCM04250.1 - 1.6e-11 43.6 0.0 3e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CCM04250.1 - 6.8e-07 28.7 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CCM04250.1 - 4.1e-05 23.5 0.2 0.00014 21.8 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCM04250.1 - 0.0013 17.7 0.1 0.0022 16.9 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UPF0020 PF01170.13 CCM04250.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 KR PF08659.5 CCM04250.1 - 0.0033 17.1 0.3 0.078 12.6 0.2 2.2 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CCM04250.1 - 0.021 13.7 0.2 0.22 10.3 0.1 2.5 1 1 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 CCM04251.1 - 1.4e-21 77.0 0.1 2.2e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM04251.1 - 2.1e-18 66.0 0.0 3.3e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCM04251.1 - 1.2e-15 57.9 0.2 4.1e-15 56.2 0.1 1.9 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCM04251.1 - 1.1e-09 37.5 0.2 4.3e-09 35.6 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CCM04251.1 - 3.2e-06 26.5 0.1 2.8e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 CCM04251.1 - 1.4e-05 25.0 1.7 2.2e-05 24.4 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCM04251.1 - 0.00044 19.2 0.1 0.0007 18.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CCM04251.1 - 0.0011 18.6 0.9 0.0039 16.8 0.2 2.2 2 1 0 2 2 2 1 KR domain Toprim_3 PF13362.1 CCM04251.1 - 0.043 14.0 0.1 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Toprim domain Pkinase PF00069.20 CCM04252.1 - 3.9e-46 157.3 0.0 6.9e-25 87.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM04252.1 - 8.8e-23 80.6 0.0 1e-11 44.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCM04252.1 - 1.1e-08 34.4 0.0 3.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCM04252.1 - 3.9e-06 26.7 0.2 2.4e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3316 PF11777.3 CCM04252.1 - 0.059 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) RNB PF00773.14 CCM04254.1 - 4.2e-50 170.8 0.0 6.5e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 RNB domain p450 PF00067.17 CCM04255.1 - 2.1e-69 234.2 0.0 2.7e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP_synt_H PF05493.8 CCM04256.1 - 6.8e-24 83.7 5.4 7.9e-24 83.5 3.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 CCM04256.1 - 0.00033 20.1 1.2 0.00033 20.1 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) ARL6IP6 PF15062.1 CCM04256.1 - 0.024 14.5 0.1 0.026 14.4 0.1 1.3 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix Intg_mem_TP0381 PF09529.5 CCM04256.1 - 0.03 13.5 1.1 0.033 13.4 0.8 1.0 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) Glucos_trans_II PF14264.1 CCM04256.1 - 0.035 13.1 1.1 0.039 12.9 0.7 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF1469 PF07332.6 CCM04256.1 - 0.039 13.6 0.9 0.045 13.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF4149 PF13664.1 CCM04256.1 - 0.082 12.9 0.8 0.085 12.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Cyto_ox_2 PF02322.10 CCM04256.1 - 0.085 12.0 2.0 0.092 11.8 1.4 1.0 1 0 0 1 1 1 0 Cytochrome oxidase subunit II DUF4173 PF13777.1 CCM04256.1 - 0.12 11.6 5.1 0.14 11.3 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) DUF2142 PF09913.4 CCM04256.1 - 0.12 10.9 0.9 0.13 10.9 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) RhodobacterPufX PF11511.3 CCM04256.1 - 0.17 11.2 0.1 0.17 11.2 0.1 1.5 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF2484 PF10658.4 CCM04256.1 - 0.18 11.9 4.1 0.23 11.6 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) DUF3488 PF11992.3 CCM04256.1 - 0.36 9.4 4.2 0.42 9.2 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Internalin_N PF12354.3 CCM04256.1 - 0.98 9.0 5.0 1.3 8.6 0.3 2.0 1 1 1 2 2 2 0 Bacterial adhesion/invasion protein N terminal DUF4381 PF14316.1 CCM04256.1 - 2.2 8.4 5.1 7 6.7 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) YrhC PF14143.1 CCM04256.1 - 2.6 8.0 4.4 6.1 6.8 0.1 2.0 1 1 1 2 2 2 0 YrhC-like protein HAMP PF00672.20 CCM04256.1 - 3.1 8.0 5.5 24 5.2 0.1 2.1 2 0 0 2 2 2 0 HAMP domain DUF4006 PF13179.1 CCM04256.1 - 8.1 6.0 6.3 17 5.0 0.6 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF4006) Methyltransf_23 PF13489.1 CCM04257.1 - 4.9e-06 26.3 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM04257.1 - 0.0015 18.1 0.1 0.66 9.5 0.2 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 CCM04257.1 - 0.0032 17.8 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM04257.1 - 0.036 14.5 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 CCM04257.1 - 0.08 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW zf-C3HC PF07967.8 CCM04258.1 - 1.6e-28 99.0 0.0 5.8e-24 84.3 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 CCM04258.1 - 2.6e-18 65.6 0.5 5.7e-12 45.3 0.0 3.0 3 0 0 3 3 3 2 Rsm1-like DM PF00751.13 CCM04258.1 - 0.084 12.4 0.2 5.8 6.5 0.0 2.7 2 0 0 2 2 2 0 DM DNA binding domain DUF2370 PF10176.4 CCM04259.1 - 3.7e-57 193.3 0.5 1.2e-56 191.7 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) SLAC1 PF03595.12 CCM04259.1 - 0.00014 20.6 2.7 0.0014 17.3 0.6 2.0 2 0 0 2 2 2 2 Voltage-dependent anion channel DUF2668 PF10873.3 CCM04259.1 - 0.037 14.2 1.3 0.037 14.2 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Epimerase PF01370.16 CCM04261.1 - 3.7e-21 75.6 0.1 6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM04261.1 - 1.7e-11 44.4 0.3 2.7e-11 43.8 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCM04261.1 - 3.2e-10 39.1 0.0 5.9e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCM04261.1 - 4.2e-10 38.9 0.1 4.3e-07 29.1 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.8 CCM04261.1 - 0.0011 18.3 0.5 0.0017 17.6 0.3 1.5 1 1 0 1 1 1 1 NmrA-like family SLH PF00395.15 CCM04261.1 - 0.0039 16.9 0.6 0.011 15.4 0.4 1.8 1 0 0 1 1 1 1 S-layer homology domain adh_short PF00106.20 CCM04261.1 - 0.11 12.3 4.8 1.9 8.3 1.3 2.8 2 1 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.16 CCM04264.1 - 4.8e-25 88.3 0.2 1.3e-20 73.8 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM04264.1 - 4.2e-19 68.3 0.1 3.1e-17 62.1 0.0 2.6 3 1 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCM04264.1 - 8.7e-16 58.4 2.4 2.5e-14 53.6 1.6 2.4 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCM04264.1 - 4.8e-12 45.3 0.2 1.1e-11 44.1 0.1 1.6 1 1 0 1 1 1 1 Male sterility protein UPF0020 PF01170.13 CCM04264.1 - 7.9e-07 28.8 0.0 0.031 13.8 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 adh_short PF00106.20 CCM04264.1 - 5.7e-06 26.3 2.9 1.4e-05 25.0 1.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 CCM04264.1 - 2e-05 23.9 0.3 4.8e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 NmrA-like family Methyltransf_26 PF13659.1 CCM04264.1 - 4.5e-05 23.4 0.0 0.091 12.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CCM04264.1 - 0.00055 19.3 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Polysacc_synt_2 PF02719.10 CCM04264.1 - 0.00086 18.2 0.1 0.0014 17.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CCM04264.1 - 0.0022 17.6 1.2 0.019 14.6 0.9 2.1 1 1 0 1 1 1 1 KR domain SBP_bac_1 PF01547.20 CCM04264.1 - 0.046 13.4 6.4 2.3 7.8 0.1 2.8 3 1 0 3 3 3 0 Bacterial extracellular solute-binding protein Eco57I PF07669.6 CCM04264.1 - 0.061 13.6 0.0 21 5.5 0.0 2.8 3 0 0 3 3 3 0 Eco57I restriction-modification methylase Glyco_transf_20 PF00982.16 CCM04265.1 - 6.4e-187 621.7 0.0 4.4e-186 618.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CCM04265.1 - 0.0074 15.7 0.3 2.9 7.2 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferases group 1 DNA_pol3_delta2 PF13177.1 CCM04266.1 - 1.2e-12 47.8 0.0 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CCM04266.1 - 3.7e-07 30.4 0.4 7.4e-07 29.4 0.3 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCM04266.1 - 0.00025 19.8 0.0 0.00033 19.4 0.0 1.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCM04266.1 - 0.00038 20.5 0.4 0.062 13.2 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 CCM04266.1 - 0.00042 19.8 0.0 0.00065 19.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 CCM04266.1 - 0.00043 20.4 0.5 0.0021 18.1 0.3 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCM04266.1 - 0.00047 19.2 0.2 0.22 10.5 0.0 2.5 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CCM04266.1 - 0.0015 17.7 0.2 0.0053 15.9 0.1 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CCM04266.1 - 0.0015 18.5 0.2 0.037 14.0 0.2 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_29 PF13555.1 CCM04266.1 - 0.0042 16.5 0.0 0.0078 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 CCM04266.1 - 0.011 15.4 0.1 0.024 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CCM04266.1 - 0.016 14.6 0.1 0.04 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain TSC21 PF15217.1 CCM04266.1 - 0.033 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 TSC21 family Bac_DnaA PF00308.13 CCM04266.1 - 0.044 13.4 1.2 1 8.9 0.1 2.4 1 1 1 2 2 2 0 Bacterial dnaA protein T4SS-DNA_transf PF02534.9 CCM04266.1 - 0.064 11.8 0.0 0.096 11.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AAA_23 PF13476.1 CCM04266.1 - 0.066 13.5 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 CCM04266.1 - 0.079 11.7 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ank_2 PF12796.2 CCM04267.1 - 1.6e-13 50.8 0.1 2.7e-12 46.8 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCM04267.1 - 2e-11 43.0 0.7 4.5e-07 29.3 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 CCM04267.1 - 8.9e-09 35.3 0.2 0.0016 18.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.13 CCM04267.1 - 2.2e-07 30.6 13.9 2.2e-07 30.6 9.6 1.9 2 0 0 2 2 2 1 MYND finger Ank_4 PF13637.1 CCM04267.1 - 9.3e-07 29.2 2.4 0.00016 22.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM04267.1 - 1.1e-06 28.2 0.2 2.7e-05 23.9 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat SEC-C PF02810.10 CCM04267.1 - 0.019 14.4 22.2 0.041 13.4 1.1 3.4 3 0 0 3 3 3 0 SEC-C motif PNP_UDP_1 PF01048.15 CCM04268.1 - 4e-27 94.7 0.0 4.8e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_tran_WecB PF03808.8 CCM04268.1 - 0.034 13.5 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family HMG_box PF00505.14 CCM04269.1 - 1.9e-15 56.8 1.9 3.4e-15 56.0 1.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM04269.1 - 1.3e-13 51.0 0.7 2.8e-13 50.0 0.5 1.5 1 0 0 1 1 1 1 HMG-box domain adh_short_C2 PF13561.1 CCM04270.1 - 3.4e-29 102.3 0.1 5.2e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCM04270.1 - 9.2e-12 45.1 1.7 1.2e-11 44.8 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04270.1 - 3.2e-05 23.6 0.7 5.3e-05 22.9 0.1 1.6 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 CCM04270.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase His_biosynth PF00977.16 CCM04270.1 - 0.098 11.9 0.4 0.22 10.7 0.1 1.7 2 1 0 2 2 2 0 Histidine biosynthesis protein Flavodoxin_4 PF12682.2 CCM04270.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin Glyco_hydro_31 PF01055.21 CCM04271.1 - 1.8e-161 537.9 1.3 2.3e-161 537.5 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCM04271.1 - 0.00094 18.9 0.1 0.0033 17.2 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Lipocalin_4 PF13648.1 CCM04271.1 - 0.042 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Lipocalin-like domain F-box-like PF12937.2 CCM04274.1 - 0.014 15.1 1.0 0.014 15.1 0.7 3.3 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.2 CCM04275.1 - 0.0063 16.2 1.4 0.015 15.0 1.0 1.7 1 0 0 1 1 1 1 F-box-like Utp12 PF04003.7 CCM04275.1 - 0.098 12.5 0.0 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Dip2/Utp12 Family p450 PF00067.17 CCM04276.1 - 7.2e-62 209.4 0.0 2e-61 207.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 CCM04276.1 - 1e-05 25.1 1.3 4.2e-05 23.1 0.9 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM04276.1 - 0.041 13.5 1.4 0.13 11.9 0.0 2.6 2 0 0 2 2 2 0 F-box domain p450 PF00067.17 CCM04277.1 - 5.1e-58 196.7 0.0 8.6e-58 195.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 CCM04278.1 - 0.047 13.4 5.4 0.044 13.5 2.4 2.0 2 0 0 2 2 2 0 F-box-like AAA_12 PF13087.1 CCM04279.1 - 2.6e-36 124.9 0.0 6.1e-36 123.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCM04279.1 - 2.4e-25 89.5 0.1 9.5e-24 84.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM04279.1 - 5.8e-08 32.3 0.0 2.1e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCM04279.1 - 2.9e-07 30.2 0.8 2.6e-06 27.1 0.0 2.9 4 0 0 4 4 4 1 AAA domain zf-CCCH PF00642.19 CCM04279.1 - 7e-06 25.5 8.9 0.00013 21.5 0.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UvrD_C_2 PF13538.1 CCM04279.1 - 0.0004 20.4 0.0 0.0013 18.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain zf-RING_2 PF13639.1 CCM04279.1 - 0.0013 18.4 0.1 0.0013 18.4 0.1 2.8 3 1 1 4 4 3 1 Ring finger domain DUF2075 PF09848.4 CCM04279.1 - 0.0015 17.5 0.1 0.16 10.9 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 CCM04279.1 - 0.0068 15.8 0.0 0.043 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 CCM04279.1 - 0.024 14.6 0.4 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 CCM04279.1 - 0.044 13.5 0.0 0.17 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCM04279.1 - 0.067 13.3 0.0 0.56 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCM04279.1 - 0.079 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCM04279.1 - 0.1 13.3 0.0 0.38 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain zf-CCCH_2 PF14608.1 CCM04279.1 - 0.18 11.8 1.7 0.48 10.4 1.2 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Mac PF12464.3 CCM04279.1 - 0.23 11.5 2.7 0.29 11.1 0.3 2.4 2 0 0 2 2 2 0 Maltose acetyltransferase DUF1191 PF06697.7 CCM04280.1 - 0.00083 18.2 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 CCM04280.1 - 0.0043 15.3 0.2 0.017 13.4 0.0 1.8 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF844 PF05815.6 CCM04280.1 - 0.008 15.0 0.1 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF844) PepSY_TM_2 PF13703.1 CCM04280.1 - 0.16 12.1 0.1 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Podoplanin PF05808.6 CCM04280.1 - 0.17 11.4 7.5 0.37 10.3 5.2 1.5 1 0 0 1 1 1 0 Podoplanin Shisa PF13908.1 CCM04280.1 - 2.2 8.4 0.0 2.2 8.4 0.0 3.1 3 1 0 4 4 4 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 CCM04280.1 - 2.5 7.7 11.0 11 5.7 7.6 1.9 1 1 0 1 1 1 0 TMEM154 protein family Brix PF04427.13 CCM04281.1 - 9.2e-30 103.7 0.0 1.2e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain DBR1 PF05011.8 CCM04282.1 - 7.9e-31 106.9 0.0 1.3e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CCM04282.1 - 7.3e-07 28.7 0.9 1.1e-06 28.2 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3328 PF11807.3 CCM04285.1 - 4.4e-53 180.1 0.8 5.9e-53 179.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2360 PF10152.4 CCM04287.1 - 8.9 6.5 8.1 11 6.3 5.6 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) GFO_IDH_MocA PF01408.17 CCM04289.1 - 2.9e-05 24.5 0.0 6.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_C13 PF01650.13 CCM04290.1 - 2.1e-44 151.7 0.3 3e-44 151.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase C13 family HAMP PF00672.20 CCM04291.1 - 1.4e-48 162.9 24.1 1.2e-07 31.8 0.1 8.3 7 0 0 7 7 7 7 HAMP domain HATPase_c PF02518.21 CCM04291.1 - 1.6e-27 95.3 0.1 5e-27 93.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCM04291.1 - 2.8e-25 88.4 0.8 1.4e-23 83.0 0.2 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 CCM04291.1 - 1.6e-17 63.2 1.0 6.9e-17 61.2 0.7 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Syntaxin PF00804.20 CCM04291.1 - 0.94 9.6 5.0 12 6.1 0.2 4.2 3 2 0 3 3 3 0 Syntaxin AcylCoA_dehyd_C PF12186.3 CCM04291.1 - 3.3 7.5 12.2 81 3.1 0.0 6.2 7 0 0 7 7 7 0 Acyl-CoA dehydrogenase C terminal F-box-like_2 PF13013.1 CCM04293.1 - 0.00058 19.5 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain DEAD PF00270.24 CCM04294.1 - 2.3e-29 102.0 0.0 3.3e-28 98.2 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM04294.1 - 1e-20 73.3 0.0 2.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM04294.1 - 2.1e-08 34.2 0.5 1.4e-07 31.4 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCM04294.1 - 0.0086 15.8 0.2 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CCM04294.1 - 0.51 10.4 5.7 0.29 11.2 0.5 2.7 2 1 0 2 2 2 0 AAA domain XLF PF09302.6 CCM04295.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) DUF3511 PF12023.3 CCM04295.1 - 0.05 12.9 0.5 0.097 12.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) TFIIF_alpha PF05793.7 CCM04295.1 - 2.5 6.3 13.9 3.5 5.8 9.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) G-patch PF01585.18 CCM04296.1 - 2.6e-09 36.7 0.7 6e-09 35.5 0.5 1.7 1 0 0 1 1 1 1 G-patch domain FHA PF00498.21 CCM04296.1 - 5.1e-08 32.9 0.0 1.7e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 FHA domain G-patch_2 PF12656.2 CCM04296.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site LRR_6 PF13516.1 CCM04297.1 - 0.0064 16.4 0.6 0.4 10.8 0.0 3.8 4 0 0 4 4 4 1 Leucine Rich repeat LRR_8 PF13855.1 CCM04297.1 - 0.045 13.5 1.3 1.9 8.2 0.2 3.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CCM04297.1 - 0.055 13.1 0.6 3.1 7.5 0.0 3.3 2 1 1 3 3 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCM04297.1 - 0.098 12.7 4.1 8 6.9 0.0 4.8 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 CCM04297.1 - 5.3 7.7 7.5 61 4.4 0.1 5.1 5 0 0 5 5 5 0 Leucine rich repeat Na_Ca_ex PF01699.19 CCM04299.1 - 2.1e-38 131.1 34.1 2.4e-20 72.5 9.4 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein adh_short PF00106.20 CCM04300.1 - 2.5e-60 203.1 20.2 4e-32 111.4 2.2 2.5 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 CCM04300.1 - 1.8e-28 98.3 0.0 4.5e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 CCM04300.1 - 3.6e-27 95.1 14.9 4.8e-14 52.4 1.3 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 CCM04300.1 - 1.7e-15 57.4 5.3 5.3e-10 39.4 0.9 2.6 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 CCM04300.1 - 1.9e-12 47.1 0.0 1.3e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.13 CCM04300.1 - 0.002 17.8 12.8 0.17 11.5 1.4 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4161 PF13722.1 CCM04300.1 - 0.03 14.6 1.7 0.55 10.5 0.1 2.6 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) DUF543 PF04418.7 CCM04300.1 - 8.9 6.3 9.9 9.4 6.2 0.4 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF543) UPRTase PF14681.1 CCM04301.1 - 5.2e-48 162.9 0.0 4.7e-46 156.6 0.0 2.2 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 CCM04301.1 - 6.3e-48 162.9 0.0 8.9e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 CCM04301.1 - 0.0001 23.1 0.0 0.0003 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCM04301.1 - 0.00019 21.3 0.0 0.00055 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCM04301.1 - 0.00045 20.5 0.1 0.0018 18.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCM04301.1 - 0.0019 17.3 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 CCM04301.1 - 0.016 14.9 0.0 0.92 9.3 0.0 2.8 3 0 0 3 3 3 0 Part of AAA domain CoaE PF01121.15 CCM04301.1 - 0.045 13.1 0.3 0.29 10.5 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase SOG2 PF10428.4 CCM04303.1 - 1.2 7.7 16.4 1.4 7.4 11.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PRMT5 PF05185.11 CCM04304.1 - 6.5e-155 516.4 0.0 8.2e-155 516.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Ank_4 PF13637.1 CCM04304.1 - 2.3e-14 53.4 0.0 4.2e-06 27.1 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCM04304.1 - 1.5e-13 50.8 0.0 2.6e-12 46.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCM04304.1 - 4.3e-13 49.0 0.0 3.2e-11 43.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CCM04304.1 - 7.3e-10 38.1 0.1 4.5e-06 26.2 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCM04304.1 - 3.2e-08 33.0 0.0 0.00011 22.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat ABM PF03992.11 CCM04304.1 - 0.0086 16.0 0.3 0.03 14.3 0.2 1.9 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Methyltransf_11 PF08241.7 CCM04304.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GATA PF00320.22 CCM04305.1 - 6.6e-14 50.9 3.9 1.6e-13 49.7 2.7 1.7 1 0 0 1 1 1 1 GATA zinc finger LRR_4 PF12799.2 CCM04306.1 - 2.2e-40 135.6 21.5 1.3e-09 37.4 2.0 7.2 5 1 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM04306.1 - 8.2e-28 95.9 34.7 9.1e-12 44.5 0.6 5.7 2 1 4 7 7 7 6 Leucine rich repeat LRR_9 PF14580.1 CCM04306.1 - 6e-17 61.7 12.5 5e-08 32.7 0.5 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 CCM04306.1 - 2e-15 54.4 22.0 1.4 9.2 0.1 10.7 11 0 0 11 11 11 7 Leucine Rich Repeat LRR_6 PF13516.1 CCM04306.1 - 1.2e-09 37.2 18.0 4.1 7.7 0.2 9.8 6 3 3 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 CCM04306.1 - 1.7e-09 36.3 22.0 7.5 7.2 0.0 10.3 11 1 0 11 11 11 3 Leucine rich repeat DUF4078 PF13300.1 CCM04307.1 - 2e-19 69.4 3.1 2e-19 69.4 2.2 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) DUF1180 PF06679.7 CCM04307.1 - 1.7 8.5 9.1 1.3 8.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Lactamase_B PF00753.22 CCM04308.1 - 1.4e-07 31.3 4.0 8.8e-05 22.2 0.0 2.4 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCM04308.1 - 0.00064 19.3 0.5 0.0015 18.1 0.4 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Tannase PF07519.6 CCM04309.1 - 1.1e-77 261.7 2.3 1e-76 258.5 1.6 2.1 1 1 0 1 1 1 1 Tannase and feruloyl esterase ThiS PF02597.15 CCM04309.1 - 7.1e-05 23.1 0.0 0.00058 20.2 0.0 2.4 2 0 0 2 2 2 1 ThiS family TPK_B1_binding PF04265.9 CCM04310.1 - 1.8e-18 66.0 0.3 2.4e-18 65.6 0.2 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 CCM04310.1 - 1.7e-17 63.1 0.0 2.6e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain PH PF00169.24 CCM04310.1 - 0.059 13.5 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 PH domain CS PF04969.11 CCM04311.1 - 1.2e-09 38.5 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 CS domain DUF4597 PF15366.1 CCM04311.1 - 0.065 12.8 3.1 2.8 7.5 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Cyclin_N PF00134.18 CCM04313.1 - 4.3e-42 142.6 0.3 9e-42 141.6 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCM04313.1 - 4e-24 84.8 0.0 8.8e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Tannase PF07519.6 CCM04314.1 - 9.9e-78 261.9 0.2 2.2e-77 260.7 0.1 1.5 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 CCM04314.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Tannase PF07519.6 CCM04315.1 - 4.3e-12 45.4 0.0 4.6e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Steroid_dh PF02544.11 CCM04316.1 - 4.1e-35 120.7 6.1 6.6e-35 120.0 4.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 CCM04316.1 - 0.011 15.8 0.5 0.011 15.8 0.4 1.9 2 0 0 2 2 2 0 Phospholipid methyltransferase DUF410 PF04190.8 CCM04317.1 - 4.4e-37 128.0 0.0 5.5e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_11 PF13414.1 CCM04317.1 - 0.15 11.7 1.1 9.3 5.9 0.0 3.0 2 1 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 CCM04317.1 - 0.39 10.6 2.9 1.7 8.6 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HSBP1 PF06825.7 CCM04318.1 - 3.7e-16 58.4 1.1 5e-16 58.0 0.8 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 BLOC1_2 PF10046.4 CCM04318.1 - 0.018 15.1 0.1 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 CCM04318.1 - 0.027 14.3 1.0 0.034 13.9 0.7 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.4 CCM04318.1 - 0.049 12.9 0.2 0.22 10.9 0.1 1.9 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin ApoO PF09769.4 CCM04318.1 - 0.058 13.1 0.1 0.073 12.7 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein O DUF935 PF06074.7 CCM04318.1 - 0.092 11.4 0.1 0.1 11.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Lamp PF01299.12 CCM04318.1 - 0.95 8.5 4.6 1.1 8.2 3.2 1.0 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Pol_alpha_B_N PF08418.5 CCM04318.1 - 9.1 5.7 8.2 27 4.1 5.7 1.6 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Gti1_Pac2 PF09729.4 CCM04319.1 - 9.1e-27 93.9 2.8 6e-19 68.5 0.2 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family nlz1 PF12402.3 CCM04319.1 - 0.025 14.9 0.1 0.1 12.9 0.1 2.1 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 Tfb2 PF03849.9 CCM04320.1 - 1.2e-128 428.8 0.0 1.4e-128 428.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CCM04320.1 - 2e-05 24.3 0.0 4.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ank PF00023.25 CCM04321.1 - 6.4e-47 155.0 1.4 8.4e-13 47.4 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 CCM04321.1 - 4.2e-41 139.1 0.4 1.5e-21 76.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCM04321.1 - 2.1e-40 136.3 4.4 3.1e-13 49.8 0.0 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCM04321.1 - 2.8e-35 119.5 10.7 1.4e-10 41.0 0.1 6.0 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM04321.1 - 9.5e-33 108.9 0.1 2.2e-07 30.4 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Aldo_ket_red PF00248.16 CCM04322.1 - 2.5e-49 167.6 0.0 3e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RING_2 PF13639.1 CCM04323.1 - 0.0049 16.6 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCM04323.1 - 0.016 14.8 0.1 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.3 CCM04323.1 - 0.21 11.1 0.7 8.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit MFS_1 PF07690.11 CCM04325.1 - 2.6e-31 108.6 23.6 2.6e-31 108.6 16.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM04325.1 - 1.2e-06 27.4 24.5 8.3e-06 24.6 17.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CCM04325.1 - 2.8e-06 25.9 26.9 0.0017 16.8 7.4 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Apt1 PF10351.4 CCM04325.1 - 0.23 10.2 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ATG22 PF11700.3 CCM04325.1 - 1.2 7.5 21.0 0.0084 14.6 1.9 3.9 3 1 1 4 4 4 0 Vacuole effluxer Atg22 like Pertussis_S2S3 PF02918.10 CCM04327.1 - 0.029 14.1 0.5 0.058 13.1 0.2 1.5 1 1 1 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain adh_short PF00106.20 CCM04328.1 - 3e-25 89.0 1.1 3.4e-25 88.8 0.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM04328.1 - 6e-24 85.1 0.0 7.3e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM04328.1 - 3.5e-08 33.3 0.0 6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CCM04328.1 - 0.00058 19.5 0.2 0.014 15.0 0.0 2.3 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 CCM04328.1 - 0.0015 18.0 0.1 0.0025 17.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 CCM04328.1 - 0.012 15.0 0.1 0.66 9.4 0.0 2.4 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA B12-binding PF02310.14 CCM04328.1 - 0.014 15.2 0.4 0.056 13.3 0.0 1.9 1 1 1 2 2 2 0 B12 binding domain F420_oxidored PF03807.12 CCM04328.1 - 0.14 12.5 1.0 1.1 9.7 0.1 2.7 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Transp_cyt_pur PF02133.10 CCM04329.1 - 5.3e-111 371.2 36.6 6.1e-111 371.0 25.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin BTB PF00651.26 CCM04331.1 - 6.7e-08 32.5 0.1 1.9e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 CCM04332.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Atrophin-1 PF03154.10 CCM04332.1 - 0.037 12.1 3.3 0.11 10.6 2.3 1.7 2 0 0 2 2 2 0 Atrophin-1 family O-FucT PF10250.4 CCM04333.1 - 0.078 12.0 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase zf-C2H2 PF00096.21 CCM04336.1 - 0.00046 20.3 0.4 0.00046 20.3 0.3 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM04336.1 - 0.0016 18.6 0.4 0.0016 18.6 0.3 4.2 4 2 0 4 4 4 1 C2H2-type zinc finger zf-CCHC_5 PF14787.1 CCM04336.1 - 0.01 15.2 1.0 0.029 13.8 0.7 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-H2C2_5 PF13909.1 CCM04336.1 - 0.014 15.5 5.5 2.1 8.7 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CCM04336.1 - 0.02 14.7 2.3 0.046 13.6 0.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 CCM04336.1 - 0.02 14.6 3.2 0.7 9.6 0.1 2.7 3 0 0 3 3 3 0 BED zinc finger OrfB_Zn_ribbon PF07282.6 CCM04336.1 - 0.061 12.9 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Di19 PF05605.7 CCM04336.1 - 0.062 13.4 1.5 0.85 9.7 0.2 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CCM04336.1 - 0.068 13.4 1.1 5.1 7.5 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 CCM04336.1 - 0.98 9.1 6.2 0.67 9.6 1.9 2.6 3 1 0 3 3 3 0 zinc-finger of a C2HC-type Ribosomal_60s PF00428.14 CCM04337.1 - 6.2 7.2 10.2 1.3 9.4 4.6 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C2H2_4 PF13894.1 CCM04339.1 - 0.00088 19.4 1.0 2.3 8.7 0.0 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM04339.1 - 0.0012 19.0 2.4 0.21 11.9 0.2 3.2 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 CCM04339.1 - 0.0026 17.8 1.0 0.043 13.9 0.2 2.4 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 CCM04339.1 - 0.045 14.1 4.4 0.91 9.9 0.2 2.6 2 1 0 3 3 3 0 TRAF-type zinc finger Sgf11 PF08209.6 CCM04339.1 - 0.081 12.2 0.6 0.51 9.7 0.2 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 CCM04339.1 - 1.4 9.3 5.1 5.1 7.5 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.10 CCM04339.1 - 4.4 7.1 5.5 4.3 7.1 0.0 3.0 3 1 1 4 4 4 0 BED zinc finger zf-C2H2 PF00096.21 CCM04340.1 - 8.7e-06 25.7 0.4 0.00026 21.1 0.1 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM04340.1 - 0.00014 21.9 3.3 0.0012 19.0 0.2 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CCM04340.1 - 0.01 15.5 1.2 0.038 13.6 0.2 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type OrfB_Zn_ribbon PF07282.6 CCM04340.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Di19 PF05605.7 CCM04340.1 - 0.13 12.4 0.2 0.13 12.4 0.1 3.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 CCM04340.1 - 0.51 10.6 8.5 4.7 7.6 0.0 3.7 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 CCM04341.1 - 0.002 18.3 2.7 0.019 15.2 0.1 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CCM04341.1 - 0.0046 16.8 0.1 0.014 15.2 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CCM04341.1 - 0.038 14.3 6.2 0.35 11.3 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CCM04342.1 - 0.0021 18.2 8.4 0.015 15.6 0.2 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM04342.1 - 0.022 15.1 0.4 0.022 15.1 0.3 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type LRRNT_2 PF08263.7 CCM04342.1 - 4.9 7.2 5.8 3.5 7.6 0.0 2.8 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain zf-C2H2 PF00096.21 CCM04343.1 - 1.1 9.7 5.2 0.17 12.2 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM04343.1 - 3.1 8.3 5.2 3.1 8.3 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger AAA_16 PF13191.1 CCM04345.1 - 0.0012 18.8 0.3 0.0033 17.4 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 CCM04345.1 - 0.029 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 CCM04345.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain WD40 PF00400.27 CCM04346.1 - 1.5e-140 452.6 70.3 7e-14 51.0 1.1 13.3 13 0 0 13 13 13 12 WD domain, G-beta repeat PQQ_3 PF13570.1 CCM04346.1 - 8.9e-17 60.7 1.2 3.7 7.9 0.0 11.8 11 1 1 12 12 12 1 PQQ-like domain Nucleoporin_N PF08801.6 CCM04346.1 - 5.3e-11 41.9 34.4 0.36 9.5 0.0 11.2 1 1 8 10 10 10 7 Nup133 N terminal like BBS2_Mid PF14783.1 CCM04346.1 - 1.4e-10 40.9 2.6 0.85 9.4 0.0 9.3 9 2 0 9 9 9 2 Ciliary BBSome complex subunit 2, middle region SLH PF00395.15 CCM04346.1 - 9.5e-09 34.8 0.0 12 5.7 0.0 8.9 11 0 0 11 11 11 1 S-layer homology domain Nup160 PF11715.3 CCM04346.1 - 3.4e-08 32.0 27.8 0.45 8.5 0.1 10.2 3 3 7 10 10 10 6 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCM04346.1 - 3.4e-06 26.7 15.1 0.019 14.4 1.4 5.1 1 1 1 2 2 2 1 PQQ-like domain Peptidase_S9_N PF02897.10 CCM04346.1 - 0.0022 16.6 4.3 23 3.4 0.0 6.6 3 3 3 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4353 PF14262.1 CCM04346.1 - 0.004 16.4 0.3 2.6 7.1 0.0 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF4353) PD40 PF07676.7 CCM04346.1 - 0.02 14.5 0.1 1e+02 2.7 0.0 5.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat VID27 PF08553.5 CCM04346.1 - 0.16 10.2 3.5 10 4.1 0.0 3.6 4 1 1 5 5 5 0 VID27 cytoplasmic protein EFF-AFF PF14884.1 CCM04346.1 - 1 7.3 2.1 17 3.3 0.0 3.3 2 1 2 4 4 4 0 Type I membrane glycoproteins cell-cell fusogen ADH_N PF08240.7 CCM04347.1 - 8.5e-12 44.8 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3735 PF12537.3 CCM04348.1 - 0.39 10.7 3.2 0.98 9.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) Pkinase PF00069.20 CCM04349.1 - 8.3e-07 28.4 0.0 1.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CCM04350.1 - 2.1e-51 174.5 0.0 2.6e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM04350.1 - 7.5e-31 107.1 0.0 9e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM04350.1 - 6.9e-06 25.2 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCM04350.1 - 0.0006 18.9 0.0 0.0011 18.1 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Toxin_42 PF15522.1 CCM04350.1 - 0.006 15.7 0.4 0.0093 15.1 0.3 1.2 1 0 0 1 1 1 1 Putative toxin 42 APH PF01636.18 CCM04350.1 - 0.015 15.0 0.5 0.19 11.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Synaptobrevin PF00957.16 CCM04351.1 - 4.2e-34 115.9 4.3 5.3e-34 115.7 3.0 1.1 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 CCM04351.1 - 0.011 14.3 0.8 0.013 14.0 0.6 1.1 1 0 0 1 1 1 0 TMEM117 protein family Shisa PF13908.1 CCM04351.1 - 0.12 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2842 PF11003.3 CCM04352.1 - 0.75 9.7 0.1 0.75 9.7 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2842) RRM_1 PF00076.17 CCM04353.1 - 1.5e-53 178.2 0.0 2.5e-16 59.0 0.0 6.5 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04353.1 - 3.1e-44 148.7 0.0 3.7e-11 42.8 0.0 5.9 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM04353.1 - 6.4e-11 41.9 0.0 0.27 11.0 0.0 5.7 6 0 0 6 6 6 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAP_assoc PF03828.14 CCM04354.1 - 9.8e-06 25.4 0.0 0.0028 17.5 0.0 3.6 3 1 0 3 3 3 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CCM04354.1 - 3.7e-05 23.9 0.0 7.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain ERAP1_C PF11838.3 CCM04355.1 - 8.9e-38 130.3 0.0 4.6e-37 127.9 0.0 1.8 1 1 1 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.15 CCM04356.1 - 2.6e-71 240.7 0.2 4.8e-70 236.6 0.2 2.4 1 1 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CCM04356.1 - 1.7e-05 24.8 0.1 3.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Paf67 PF10255.4 CCM04357.1 - 5.1e-152 506.4 0.1 6.5e-152 506.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 CCM04357.1 - 0.014 15.2 0.0 0.087 12.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCM04357.1 - 0.044 13.7 0.2 4.4 7.3 0.0 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat SNARE PF05739.14 CCM04358.1 - 3.5e-11 42.6 0.6 3.5e-11 42.6 0.4 3.0 2 1 1 3 3 3 1 SNARE domain Sec20 PF03908.8 CCM04358.1 - 0.069 12.8 0.2 0.78 9.4 0.0 2.6 2 1 0 2 2 2 0 Sec20 Mss4 PF04421.8 CCM04359.1 - 9.3e-10 38.2 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_1 PF00583.19 CCM04359.1 - 2.4e-07 30.6 0.0 5.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCM04359.1 - 2.8e-06 27.3 0.0 5.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCM04359.1 - 0.0091 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCM04359.1 - 0.022 14.4 0.0 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_13 PF13880.1 CCM04359.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF3749 PF12568.3 CCM04359.1 - 0.052 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCM04359.1 - 0.093 12.6 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 CCM04361.1 - 7.6e-72 241.5 0.0 9.7e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM04361.1 - 1.3e-35 122.7 0.0 1.7e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCM04361.1 - 9.7e-12 45.2 3.5 2.5e-11 43.9 2.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCM04361.1 - 0.00017 20.6 0.0 0.00036 19.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCM04361.1 - 0.021 14.5 0.0 0.044 13.5 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CCM04361.1 - 0.039 13.0 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GATase PF00117.23 CCM04362.1 - 6.2e-10 38.8 0.1 2.2e-09 37.0 0.1 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCM04362.1 - 0.0027 17.1 0.3 0.015 14.7 0.2 2.3 1 1 0 1 1 1 1 Peptidase C26 SSF PF00474.12 CCM04363.1 - 7.9e-20 70.8 34.5 1.4e-19 70.0 23.9 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Pex24p PF06398.6 CCM04364.1 - 0.00011 21.1 5.4 0.00013 20.9 3.7 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin polyprenyl_synt PF00348.12 CCM04365.1 - 1.5e-67 227.1 0.0 1.9e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase YqeY PF09424.5 CCM04366.1 - 1.2e-17 64.1 0.8 3e-17 62.7 0.5 1.6 1 1 0 1 1 1 1 Yqey-like protein TipAS PF07739.8 CCM04366.1 - 0.25 11.6 3.0 0.66 10.2 0.1 2.4 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain DUF2781 PF10914.3 CCM04367.1 - 0.0018 18.0 0.1 0.004 16.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) zf-rbx1 PF12678.2 CCM04367.1 - 0.0021 18.1 0.1 0.0046 17.0 0.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger Transposase_28 PF04195.7 CCM04367.1 - 0.0076 15.5 0.1 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Putative gypsy type transposon zf-RING_2 PF13639.1 CCM04367.1 - 0.27 11.0 4.2 3.8 7.4 2.9 2.3 1 1 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 CCM04367.1 - 0.29 10.8 4.5 0.95 9.2 3.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Amidohydro_3 PF07969.6 CCM04368.1 - 7.6e-67 226.2 0.1 9e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CCM04368.1 - 2.8e-05 24.2 0.2 0.23 11.4 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 CCM04368.1 - 0.0001 22.0 0.0 0.0055 16.4 0.0 2.6 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 CCM04368.1 - 0.0055 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase SNF2_N PF00176.18 CCM04369.1 - 8.9e-22 77.2 0.0 1.3e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CCM04369.1 - 0.027 14.3 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2439 PF10382.4 CCM04369.1 - 0.027 14.6 0.1 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) SNF2_N PF00176.18 CCM04370.1 - 4.8e-23 81.3 0.0 6.9e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM04370.1 - 1.2e-10 41.1 0.0 2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCM04370.1 - 1.2e-06 27.5 0.0 2.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Peptidase_M22 PF00814.20 CCM04372.1 - 1.2e-69 234.7 0.0 1.9e-69 234.1 0.0 1.3 1 1 0 1 1 1 1 Glycoprotease family FAD_binding_3 PF01494.14 CCM04373.1 - 7.9e-15 54.7 0.2 3.3e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CCM04373.1 - 3e-12 46.1 0.7 8.7e-07 28.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCM04373.1 - 3.3e-09 36.6 0.3 2.1e-08 34.0 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCM04373.1 - 4.2e-08 32.0 0.0 7.9e-08 31.1 0.0 1.4 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 CCM04373.1 - 7.8e-08 31.5 0.6 1.3e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CCM04373.1 - 3.8e-07 30.4 0.0 1.2e-06 28.8 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCM04373.1 - 1.5e-06 28.2 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CCM04373.1 - 4.3e-06 26.3 0.0 8.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 CCM04373.1 - 3.6e-05 22.8 0.5 0.0003 19.8 0.1 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 CCM04373.1 - 0.00017 20.6 0.6 0.00038 19.4 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 CCM04373.1 - 0.00022 19.9 0.2 0.0046 15.6 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 CCM04373.1 - 0.00047 20.2 0.2 0.0021 18.1 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM04373.1 - 0.00059 19.0 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 CCM04373.1 - 0.0089 15.8 1.1 0.71 9.6 1.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 CCM04373.1 - 0.013 14.6 0.2 0.17 10.9 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ApbA PF02558.11 CCM04373.1 - 0.04 13.3 0.1 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 CCM04373.1 - 0.066 12.2 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCM04374.1 - 1.6e-14 53.7 0.0 2.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCM04374.1 - 1e-12 47.6 0.1 3.1e-07 29.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCM04374.1 - 3.4e-09 36.5 0.2 9.4e-09 35.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCM04374.1 - 9.3e-07 29.1 0.0 2.3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCM04374.1 - 1.2e-06 27.7 0.0 1.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CCM04374.1 - 6.2e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM04374.1 - 1.7e-05 23.5 0.1 7e-05 21.4 0.1 1.9 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 CCM04374.1 - 2.7e-05 24.1 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM04374.1 - 3.6e-05 22.8 0.1 0.00027 19.9 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 CCM04374.1 - 0.0002 20.0 0.0 0.016 13.8 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 CCM04374.1 - 0.00027 19.9 0.1 0.00048 19.1 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 CCM04374.1 - 0.00075 19.1 0.1 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 CCM04374.1 - 0.00096 18.3 0.1 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 CCM04374.1 - 0.0014 18.3 0.2 0.041 13.6 0.1 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 CCM04374.1 - 0.021 13.9 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 CCM04374.1 - 0.099 11.7 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 CCM04374.1 - 0.15 12.0 0.1 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Aldo_ket_red PF00248.16 CCM04375.1 - 7.2e-62 208.7 0.0 8.5e-62 208.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_GP20 PF06810.6 CCM04376.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Con-6 PF10346.4 CCM04377.1 - 2.2e-44 148.5 16.4 5.8e-17 60.8 1.2 3.6 4 0 0 4 4 4 3 Conidiation protein 6 SpoIIIAH PF12685.2 CCM04377.1 - 0.0053 16.2 2.1 0.14 11.6 0.0 2.9 1 1 1 2 2 2 1 SpoIIIAH-like protein BEX PF04538.7 CCM04377.1 - 0.15 12.3 1.6 1.8 8.8 0.5 2.2 2 0 0 2 2 2 0 Brain expressed X-linked like family YhzD PF14120.1 CCM04377.1 - 3.5 7.6 8.3 18 5.2 0.1 3.4 4 0 0 4 4 4 0 YhzD-like protein ATP-synt_DE PF00401.15 CCM04377.1 - 3.8 7.4 8.3 3.6 7.5 0.0 3.2 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain adh_short PF00106.20 CCM04378.1 - 2.4e-21 76.3 0.3 3.6e-21 75.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM04378.1 - 3.4e-11 43.3 0.0 4.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM04378.1 - 7.7e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 KR domain p450 PF00067.17 CCM04380.1 - 2.1e-39 135.3 0.0 6.1e-39 133.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Vitellogenin_N PF01347.17 CCM04382.1 - 0.016 13.4 0.1 0.019 13.2 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region E1-E2_ATPase PF00122.15 CCM04383.1 - 8.1e-22 77.3 0.0 1.6e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCM04383.1 - 1.1e-17 64.8 0.5 2.7e-17 63.5 0.2 1.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCM04383.1 - 5.1e-15 56.4 1.2 9.2e-14 52.3 0.8 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCM04383.1 - 1.5e-13 50.4 0.0 4.9e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCM04383.1 - 0.025 14.1 0.1 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RsgI_N PF12791.2 CCM04383.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma factor N-terminus TPR_11 PF13414.1 CCM04385.1 - 7.8e-14 51.0 8.5 9.3e-08 31.6 0.3 3.8 3 1 2 5 5 5 3 TPR repeat PB1 PF00564.19 CCM04385.1 - 7.1e-13 48.0 0.0 1.7e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.23 CCM04385.1 - 3.1e-09 36.0 6.7 1.6e-05 24.2 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCM04385.1 - 6.3e-08 31.9 5.2 0.0012 18.5 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCM04385.1 - 3.3e-07 29.6 2.9 6.3e-05 22.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCM04385.1 - 5e-06 26.3 3.5 0.0014 18.5 0.6 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM04385.1 - 0.00041 20.9 1.1 0.032 14.9 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM04385.1 - 0.0043 16.7 0.7 0.046 13.5 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCM04385.1 - 0.0045 17.0 0.1 0.46 10.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCM04385.1 - 0.0048 17.4 1.5 0.052 14.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCM04385.1 - 0.21 12.1 3.1 23 5.7 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Pkinase PF00069.20 CCM04386.1 - 4.5e-70 235.7 0.0 5.5e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM04386.1 - 3.2e-29 101.7 0.0 4.6e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM04386.1 - 0.01 15.6 0.1 0.031 13.9 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CCM04386.1 - 0.084 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCM04386.1 - 0.12 11.2 0.0 0.28 10.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Aldo_ket_red PF00248.16 CCM04387.1 - 4.2e-56 189.8 0.0 5e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.5 CCM04387.1 - 0.15 11.8 0.0 18 5.1 0.0 3.1 3 0 0 3 3 3 0 Slx4 endonuclease Atrophin-1 PF03154.10 CCM04390.1 - 0.01 14.0 0.4 0.01 14.0 0.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF3782 PF12644.2 CCM04390.1 - 0.028 14.2 0.5 0.05 13.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) HMG_box PF00505.14 CCM04391.1 - 1.3e-11 44.5 0.3 2.8e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM04391.1 - 0.03 14.6 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain Thioredoxin PF00085.15 CCM04393.1 - 1.1e-55 185.7 0.0 9.4e-27 92.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin UQ_con PF00179.21 CCM04393.1 - 1.5e-50 170.2 0.0 2.3e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ERp29 PF07749.7 CCM04393.1 - 1.9e-21 76.4 0.1 4.3e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 CCM04393.1 - 2.5e-19 69.5 0.1 2.7e-09 37.2 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CCM04393.1 - 7.3e-11 41.9 0.0 0.00039 20.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CCM04393.1 - 4.1e-10 39.6 0.3 0.00045 20.2 0.0 4.1 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_6 PF13848.1 CCM04393.1 - 1.8e-08 34.4 0.0 0.0059 16.4 0.0 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Redoxin PF08534.5 CCM04393.1 - 4.1e-05 23.1 0.1 0.023 14.2 0.0 2.3 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.16 CCM04393.1 - 0.00011 21.8 0.0 0.099 12.3 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Prok-E2_B PF14461.1 CCM04393.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Glutaredoxin PF00462.19 CCM04393.1 - 0.0066 16.4 0.2 0.25 11.3 0.0 2.7 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_4 PF13462.1 CCM04393.1 - 0.0067 16.4 0.6 2.5 8.0 0.0 3.2 3 1 1 4 4 4 1 Thioredoxin RWD PF05773.17 CCM04393.1 - 0.0082 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain Thioredoxin_9 PF14595.1 CCM04393.1 - 0.013 15.0 1.1 2.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_3 PF13192.1 CCM04393.1 - 0.024 14.4 0.0 0.52 10.1 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain ABC_tran PF00005.22 CCM04394.1 - 7.2e-32 110.5 0.1 2.4e-17 63.4 0.0 3.2 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CCM04394.1 - 6.5e-14 51.2 4.9 1.6e-13 49.9 3.4 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CCM04394.1 - 7.7e-14 52.3 4.0 0.01 15.8 0.0 4.5 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 CCM04394.1 - 9.3e-10 38.1 3.6 0.013 14.7 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 CCM04394.1 - 5.9e-07 28.8 3.2 5.9e-07 28.8 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 CCM04394.1 - 7.4e-06 26.1 0.0 0.0081 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CCM04394.1 - 1.3e-05 25.3 0.0 0.1 12.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 CCM04394.1 - 2e-05 23.8 1.4 4.9 6.0 0.1 4.1 3 1 1 4 4 4 0 AAA ATPase domain AAA_17 PF13207.1 CCM04394.1 - 2.7e-05 24.9 0.4 0.11 13.2 0.1 3.1 2 2 0 2 2 2 2 AAA domain Miro PF08477.8 CCM04394.1 - 4e-05 24.0 0.1 0.014 15.9 0.0 3.1 4 0 0 4 4 2 1 Miro-like protein DUF258 PF03193.11 CCM04394.1 - 5.8e-05 22.3 1.5 0.26 10.4 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 NACHT PF05729.7 CCM04394.1 - 9.5e-05 22.1 0.7 0.043 13.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 CCM04394.1 - 0.0001 22.1 0.0 0.033 14.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCM04394.1 - 0.00015 21.1 0.8 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CCM04394.1 - 0.00028 21.1 0.1 0.33 11.2 0.0 3.2 2 1 1 3 3 3 1 AAA domain Fer4_6 PF12837.2 CCM04394.1 - 0.0007 19.3 2.3 0.0007 19.3 1.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain SbcCD_C PF13558.1 CCM04394.1 - 0.00088 19.1 0.1 1.3 8.9 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 CCM04394.1 - 0.00092 19.2 0.7 0.32 10.9 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 CCM04394.1 - 0.0013 18.8 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase VirE PF05272.6 CCM04394.1 - 0.0013 18.2 0.0 0.99 8.8 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_2 PF12797.2 CCM04394.1 - 0.0017 18.1 1.8 0.0017 18.1 1.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain SRP54 PF00448.17 CCM04394.1 - 0.0018 17.7 1.4 0.39 10.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_10 PF13237.1 CCM04394.1 - 0.0023 17.7 0.8 0.0023 17.7 0.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 CCM04394.1 - 0.0024 17.6 11.5 0.0047 16.7 8.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CCM04394.1 - 0.0026 18.1 1.9 0.0026 18.1 1.3 2.3 1 1 2 3 3 3 2 4Fe-4S dicluster domain UPF0079 PF02367.12 CCM04394.1 - 0.0039 16.7 0.5 0.093 12.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 CCM04394.1 - 0.0042 16.8 0.9 3.1 7.5 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CCM04394.1 - 0.0072 15.7 0.6 3.2 7.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 CCM04394.1 - 0.014 15.1 1.1 0.58 9.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Fer4_16 PF13484.1 CCM04394.1 - 0.014 16.0 0.1 0.014 16.0 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 CCM04394.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_28 PF13521.1 CCM04394.1 - 0.019 14.9 0.1 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 CCM04394.1 - 0.019 14.3 0.2 2.6 7.3 0.0 3.0 2 1 1 3 3 3 0 Thymidylate kinase AAA_23 PF13476.1 CCM04394.1 - 0.02 15.2 5.0 0.51 10.6 0.4 2.5 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CCM04394.1 - 0.022 14.6 1.2 5 7.0 0.0 3.3 2 2 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 CCM04394.1 - 0.027 14.7 12.3 0.082 13.1 8.5 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Rad17 PF03215.10 CCM04394.1 - 0.048 12.3 0.0 0.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.4 CCM04394.1 - 0.086 12.3 0.6 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_8 PF13183.1 CCM04394.1 - 0.11 12.4 8.8 0.099 12.6 0.8 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.17 CCM04394.1 - 0.14 11.0 0.2 3 6.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 CCM04394.1 - 0.24 10.9 0.1 8.5 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 CCM04394.1 - 0.32 9.4 0.0 0.32 9.4 0.0 2.5 2 1 0 3 3 3 0 AAA domain AAA_24 PF13479.1 CCM04394.1 - 0.34 10.4 1.1 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CCM04394.1 - 0.43 10.2 2.2 28 4.3 0.1 3.3 4 0 0 4 4 3 0 NTPase Fer4_4 PF12800.2 CCM04394.1 - 0.53 10.7 13.4 0.092 13.1 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 CCM04394.1 - 3.2 8.4 8.5 0.23 12.0 0.9 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain PIG-S PF10510.4 CCM04395.1 - 5.3e-124 414.7 6.6 1.5e-112 376.9 3.0 2.0 1 1 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Myb_DNA-binding PF00249.26 CCM04396.1 - 3.2e-14 52.7 0.0 1.3e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCM04396.1 - 6.9e-07 29.2 0.0 0.034 14.2 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rotamase PF00639.16 CCM04397.1 - 9.9e-16 58.2 0.2 2e-15 57.2 0.2 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CCM04397.1 - 3.7e-15 56.2 0.1 6.1e-15 55.5 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CCM04397.1 - 0.00019 22.0 0.0 0.00024 21.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Elongin_A PF06881.6 CCM04400.1 - 2.3e-12 47.2 0.0 4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Gti1_Pac2 PF09729.4 CCM04401.1 - 9.4e-29 100.4 0.3 2.2e-27 95.9 0.2 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family cwf18 PF08315.7 CCM04402.1 - 8.3e-30 103.8 7.6 1.1e-29 103.4 5.3 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF4238 PF14022.1 CCM04402.1 - 0.15 11.3 0.9 0.23 10.6 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) GTP_EFTU PF00009.22 CCM04403.1 - 2.2e-45 154.4 0.1 3.4e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CCM04403.1 - 6.8e-40 135.3 0.1 1.4e-39 134.2 0.1 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CCM04403.1 - 4.5e-16 58.4 0.0 9.6e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCM04403.1 - 2.6e-06 27.1 0.0 8e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 CCM04403.1 - 1.5e-05 24.4 0.0 3.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CCM04403.1 - 2.8e-05 24.0 0.0 8e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCM04403.1 - 0.0068 15.7 0.0 0.031 13.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCM04403.1 - 0.027 14.9 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 CCM04403.1 - 0.034 13.3 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.20 CCM04403.1 - 0.084 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Thioredoxin PF00085.15 CCM04404.1 - 2.9e-09 36.5 0.0 3.4e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCM04404.1 - 3.6e-06 27.1 0.0 3.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 CCM04404.1 - 0.016 15.1 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE A_deaminase PF00962.17 CCM04405.1 - 5.4e-54 183.3 0.0 1.1e-53 182.3 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 CCM04405.1 - 0.12 12.3 0.9 1.9 8.5 0.6 2.4 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Baculo_PEP_C PF04513.7 CCM04406.1 - 0.12 12.2 2.4 0.14 11.9 0.4 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.1 CCM04406.1 - 1.6 8.6 18.8 0.6 10.0 1.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4140 PF13600.1 CCM04406.1 - 1.8 9.0 12.8 0.59 10.6 0.5 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 CCM04406.1 - 9 5.2 17.8 23 3.8 12.3 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Asparaginase PF00710.15 CCM04407.1 - 9.5e-118 392.6 0.0 1.2e-117 392.2 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 CCM04407.1 - 9.2e-15 54.7 0.1 1.9e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCM04407.1 - 1.6e-11 43.3 5.5 2.2e-05 24.0 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCM04407.1 - 3.7e-10 39.0 1.0 0.0017 18.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CCM04407.1 - 2.4e-08 34.2 1.4 6.4e-06 26.5 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCM04407.1 - 4.6e-06 26.7 1.9 0.00092 19.3 0.2 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Trp_syntA PF00290.15 CCM04408.1 - 2.2e-85 285.3 0.1 3.1e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 CCM04408.1 - 1.8e-44 152.2 0.2 2.5e-44 151.7 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 CCM04408.1 - 0.00021 20.6 0.0 0.00066 19.0 0.0 1.8 1 0 0 1 1 1 1 Histidine biosynthesis protein PA PF02225.17 CCM04408.1 - 0.018 14.7 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 PA domain DUF812 PF05667.6 CCM04410.1 - 0.00057 18.5 3.9 0.00089 17.8 2.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF812) Muted PF14942.1 CCM04410.1 - 0.026 14.4 1.5 0.044 13.6 1.0 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Spc7 PF08317.6 CCM04410.1 - 0.084 11.5 4.4 0.12 11.0 3.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Mnd1 PF03962.10 CCM04410.1 - 0.21 11.2 6.9 0.36 10.4 4.7 1.5 1 1 0 1 1 1 0 Mnd1 family IncA PF04156.9 CCM04410.1 - 0.21 11.1 8.4 9.3 5.7 6.2 2.0 1 1 1 2 2 2 0 IncA protein DUF3323 PF11796.3 CCM04410.1 - 0.27 10.5 3.1 0.36 10.1 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) ADIP PF11559.3 CCM04410.1 - 0.29 11.0 9.1 0.16 11.8 2.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF883 PF05957.8 CCM04410.1 - 3.3 8.1 6.6 4.2 7.8 1.3 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Brix PF04427.13 CCM04411.1 - 9e-39 133.1 0.1 1.1e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 Brix domain IF-2B PF01008.12 CCM04412.1 - 4.4e-64 216.1 0.0 5.3e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family IncA PF04156.9 CCM04413.1 - 0.00046 19.8 16.3 0.00066 19.3 10.5 1.7 1 1 0 1 1 1 1 IncA protein zf-C3HC4_3 PF13920.1 CCM04413.1 - 0.00051 19.6 3.4 0.00051 19.6 2.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM04413.1 - 0.00077 19.1 4.5 0.00077 19.1 3.1 2.0 2 0 0 2 2 1 1 zinc-RING finger domain MAD PF05557.8 CCM04413.1 - 0.0011 17.1 8.0 0.0014 16.8 5.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein zf-C3HC4_2 PF13923.1 CCM04413.1 - 0.0016 18.4 3.6 0.0016 18.4 2.5 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DUF3584 PF12128.3 CCM04413.1 - 0.0048 14.3 6.4 0.0058 14.0 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TRCF PF03461.10 CCM04413.1 - 0.0062 16.4 0.4 0.013 15.4 0.2 1.5 1 1 0 1 1 1 1 TRCF domain zf-RING_2 PF13639.1 CCM04413.1 - 0.01 15.6 6.1 0.011 15.5 2.5 2.2 2 0 0 2 2 2 0 Ring finger domain Syntaxin PF00804.20 CCM04413.1 - 0.011 15.9 3.6 0.021 14.9 2.5 1.5 1 0 0 1 1 1 0 Syntaxin AAA_13 PF13166.1 CCM04413.1 - 0.019 13.4 3.1 0.025 13.0 2.2 1.1 1 0 0 1 1 1 0 AAA domain PhaP_Bmeg PF09602.5 CCM04413.1 - 0.028 14.2 2.6 1.8 8.3 0.1 2.3 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Cob_adeno_trans PF01923.13 CCM04413.1 - 0.042 13.6 2.3 0.29 10.8 0.4 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Sigma70_ner PF04546.8 CCM04413.1 - 0.05 13.2 5.3 0.14 11.7 2.1 2.0 1 1 1 2 2 2 0 Sigma-70, non-essential region Reo_sigmaC PF04582.7 CCM04413.1 - 0.067 12.3 3.9 0.48 9.5 2.8 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein FUSC PF04632.7 CCM04413.1 - 0.091 11.1 9.5 0.12 10.8 6.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.6 CCM04413.1 - 0.11 11.1 5.7 0.16 10.5 4.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Apt1 PF10351.4 CCM04413.1 - 0.15 10.8 5.0 0.21 10.4 3.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPV_P10 PF05531.7 CCM04413.1 - 0.19 12.0 1.6 13 6.1 0.1 2.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 CCM04413.1 - 0.36 9.9 10.1 0.054 12.6 2.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-C3HC4_4 PF15227.1 CCM04413.1 - 0.37 10.7 4.2 1.1 9.1 2.9 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Syntaxin_2 PF14523.1 CCM04413.1 - 0.55 10.2 5.8 1.9 8.5 2.0 2.2 1 1 1 2 2 2 0 Syntaxin-like protein COG2 PF06148.6 CCM04413.1 - 0.58 10.0 3.4 7.5 6.4 0.0 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 CCM04413.1 - 0.98 8.3 9.4 1.4 7.8 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C3HC4 PF00097.20 CCM04413.1 - 1.1 8.9 9.4 0.085 12.5 2.8 2.0 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) OmpH PF03938.9 CCM04413.1 - 1.2 9.0 8.5 2.1 8.2 5.9 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Striatin PF08232.7 CCM04413.1 - 1.4 9.2 7.8 2.9 8.2 5.4 1.5 1 1 0 1 1 1 0 Striatin family DUF904 PF06005.7 CCM04413.1 - 1.6 9.1 12.2 0.66 10.3 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF4201 PF13870.1 CCM04413.1 - 2.4 7.5 11.7 71 2.7 8.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) KfrA_N PF11740.3 CCM04413.1 - 3 8.2 13.5 4.9 7.6 8.4 2.1 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term zf-MIZ PF02891.15 CCM04413.1 - 3.1 7.3 5.2 2.3 7.7 2.0 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 CCM04413.1 - 4.9 6.8 6.9 2 8.0 2.7 1.9 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain KH_1 PF00013.24 CCM04414.1 - 2.4e-39 132.7 8.2 1.8e-14 53.0 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCM04414.1 - 9e-30 101.7 13.4 5e-10 38.7 0.1 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCM04414.1 - 3.9e-15 55.1 5.6 1.1e-05 24.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCM04414.1 - 1.9e-05 24.1 1.3 0.35 10.5 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 CCM04414.1 - 0.0059 16.3 4.8 1.9 8.3 0.1 3.5 3 0 0 3 3 3 1 NusA-like KH domain Macoilin PF09726.4 CCM04414.1 - 1.2 7.3 4.6 1.4 7.1 3.2 1.2 1 0 0 1 1 1 0 Transmembrane protein CPDase PF07823.6 CCM04416.1 - 7.4e-15 54.9 0.0 1.3e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CCM04416.1 - 1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 CCM04416.1 - 9.2e-05 22.3 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase DUF1776 PF08643.5 CCM04418.1 - 3.1e-12 46.2 0.0 4.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF883 PF05957.8 CCM04418.1 - 0.12 12.7 0.2 0.41 11.0 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RdRP PF05183.7 CCM04418.1 - 0.27 9.8 0.0 0.39 9.3 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Mito_fiss_reg PF05308.6 CCM04418.1 - 3.6 6.9 6.4 6.9 5.9 4.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 CCM04418.1 - 8.5 5.5 7.3 17 4.5 4.8 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ATP-synt_ab PF00006.20 CCM04419.1 - 1.4e-63 214.2 0.0 2.5e-63 213.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCM04419.1 - 4.7e-26 91.4 0.7 8.9e-26 90.5 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCM04419.1 - 3.1e-22 78.5 1.1 7.3e-22 77.3 0.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.17 CCM04419.1 - 0.01 14.7 0.9 0.029 13.2 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 CCM04419.1 - 0.021 15.0 0.0 0.31 11.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CCM04419.1 - 0.023 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 CCM04419.1 - 0.024 14.2 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 CCM04419.1 - 0.03 13.7 0.1 0.064 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CCM04419.1 - 0.034 13.8 0.2 2 8.1 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CCM04419.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCM04419.1 - 0.044 12.9 0.1 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCM04419.1 - 0.044 13.7 0.3 0.15 12.0 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 CCM04419.1 - 0.046 12.8 0.1 0.08 12.0 0.1 1.4 1 0 0 1 1 1 0 KaiC Med2 PF11214.3 CCM04419.1 - 0.14 12.1 0.1 0.4 10.7 0.0 1.8 2 0 0 2 2 1 0 Mediator complex subunit 2 RNA_helicase PF00910.17 CCM04419.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase GATase_2 PF00310.16 CCM04420.1 - 1.1e-19 70.3 0.0 1.8e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.22 CCM04420.1 - 4.6e-14 52.2 0.7 7.6e-14 51.5 0.5 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 CCM04420.1 - 1.5e-13 50.8 0.0 2.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCM04420.1 - 2.1e-10 40.4 0.0 3.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCM04420.1 - 1.5e-06 27.1 0.0 3.1e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Na_Ca_ex PF01699.19 CCM04421.1 - 5.6e-40 136.1 36.6 5e-25 87.7 7.1 3.7 2 1 1 3 3 3 3 Sodium/calcium exchanger protein Na_Ca_ex PF01699.19 CCM04422.1 - 1.6e-29 102.3 19.8 1.2e-14 54.0 1.6 3.3 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 CCM04422.1 - 0.023 14.5 1.1 0.54 10.1 0.1 2.7 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Gtr1_RagA PF04670.7 CCM04423.1 - 3e-81 271.9 0.0 4.4e-81 271.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CCM04423.1 - 1.1e-07 31.4 0.0 1.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CCM04423.1 - 1.9e-05 23.9 0.0 3.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCM04423.1 - 3.3e-05 23.8 0.0 9.4e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CCM04423.1 - 0.00011 22.6 0.0 0.00024 21.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CCM04423.1 - 0.0068 15.8 0.1 0.094 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 CCM04423.1 - 0.027 14.0 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Svf1 PF08622.5 CCM04423.1 - 0.033 13.1 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Svf1-like AAA_29 PF13555.1 CCM04423.1 - 0.09 12.3 0.3 0.19 11.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DMRL_synthase PF00885.14 CCM04424.1 - 3.5e-48 162.9 0.1 3.8e-29 101.2 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase ATP_bind_3 PF01171.15 CCM04425.1 - 2e-28 99.1 0.0 3.3e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family YTH PF04146.10 CCM04426.1 - 1.1e-46 157.8 0.0 1.8e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain WD40 PF00400.27 CCM04428.1 - 5.9e-79 257.3 12.3 1.8e-11 43.4 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CCM04428.1 - 5.6e-08 31.3 6.9 0.051 11.7 0.0 5.2 2 2 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCM04428.1 - 6e-06 25.2 1.0 0.25 10.0 0.1 4.3 2 2 2 4 4 4 2 Nup133 N terminal like eIF2A PF08662.6 CCM04428.1 - 0.00029 20.5 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1652 PF07865.6 CCM04428.1 - 0.0021 17.6 0.0 8.6 6.0 0.0 4.3 5 0 0 5 5 5 2 Protein of unknown function (DUF1652) ADIP PF11559.3 CCM04428.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 CCM04428.1 - 0.11 12.3 0.6 0.21 11.4 0.4 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DASH_Dad3 PF08656.5 CCM04430.1 - 6e-23 80.3 0.2 6.8e-23 80.1 0.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 WD40 PF00400.27 CCM04431.1 - 5.3e-19 67.3 4.7 1.7e-06 27.6 0.0 4.9 4 1 0 4 4 4 4 WD domain, G-beta repeat Rax2 PF12768.2 CCM04431.1 - 0.00055 19.2 0.1 0.0078 15.4 0.0 2.4 3 0 0 3 3 3 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 CCM04431.1 - 0.0029 16.2 0.9 0.13 10.8 0.1 2.8 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 CCM04431.1 - 0.0071 16.0 0.2 0.43 10.2 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Acetyltransf_7 PF13508.1 CCM04432.1 - 6e-13 48.7 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCM04432.1 - 1.4e-09 38.0 0.0 2.8e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM04432.1 - 1.1e-06 28.6 0.0 2.8e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 CCM04432.1 - 0.0046 17.1 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCM04432.1 - 0.0087 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 CCM04432.1 - 0.013 15.3 0.0 0.2 11.5 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 CCM04432.1 - 0.017 14.8 0.0 0.06 13.0 0.0 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase FR47 PF08445.5 CCM04432.1 - 0.053 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein TPR_MLP1_2 PF07926.7 CCM04433.1 - 0.00036 20.2 6.5 0.0023 17.6 2.1 2.7 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein Lebercilin PF15619.1 CCM04433.1 - 0.00064 19.2 11.4 0.0064 15.9 6.5 2.0 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease HAUS5 PF14817.1 CCM04433.1 - 0.0042 15.6 3.3 0.004 15.7 2.3 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF3418 PF11898.3 CCM04433.1 - 0.013 13.8 1.8 0.014 13.8 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Filament PF00038.16 CCM04433.1 - 0.026 13.9 9.6 0.015 14.7 3.6 1.9 2 0 0 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 CCM04433.1 - 0.034 13.9 11.4 0.18 11.6 5.0 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 CCM04433.1 - 0.051 13.3 5.1 0.37 10.6 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lipoprotein_7 PF01540.11 CCM04433.1 - 0.052 12.6 0.5 0.057 12.4 0.4 1.0 1 0 0 1 1 1 0 Adhesin lipoprotein CorA PF01544.13 CCM04433.1 - 0.071 12.1 1.7 0.11 11.4 1.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ATG16 PF08614.6 CCM04433.1 - 0.18 11.5 10.6 0.21 11.3 3.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) STAG PF08514.6 CCM04433.1 - 0.19 11.4 3.5 0.18 11.5 1.5 1.7 1 1 0 1 1 1 0 STAG domain DUF1515 PF07439.6 CCM04433.1 - 0.19 11.5 2.1 0.49 10.2 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) COG2 PF06148.6 CCM04433.1 - 0.24 11.2 5.7 0.23 11.3 1.9 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mod_r PF07200.8 CCM04433.1 - 0.24 11.3 7.2 0.061 13.2 2.1 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Snapin_Pallidin PF14712.1 CCM04433.1 - 0.31 11.3 5.2 1.2 9.5 1.4 2.9 2 1 0 2 2 2 0 Snapin/Pallidin PspA_IM30 PF04012.7 CCM04433.1 - 0.38 10.0 10.8 0.091 12.1 5.1 1.7 2 0 0 2 2 2 0 PspA/IM30 family OmpH PF03938.9 CCM04433.1 - 0.53 10.2 3.3 0.8 9.6 2.3 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 CCM04433.1 - 0.65 9.5 7.6 0.33 10.5 1.5 2.2 2 0 0 2 2 2 0 IncA protein HR1 PF02185.11 CCM04433.1 - 0.71 9.6 8.7 4.3 7.1 1.1 3.4 3 1 0 3 3 3 0 Hr1 repeat DivIC PF04977.10 CCM04433.1 - 0.76 9.3 7.0 1.9 8.0 2.9 2.6 2 1 0 2 2 2 0 Septum formation initiator DUF4482 PF14818.1 CCM04433.1 - 0.97 10.0 7.6 1.9 9.1 5.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) DUF972 PF06156.8 CCM04433.1 - 1.1 9.5 5.2 1.2 9.5 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 CCM04433.1 - 1.3 7.8 10.8 1.9 7.3 7.5 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 CCM04433.1 - 1.8 8.4 11.1 1.2 8.9 1.9 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 CCM04433.1 - 2.6 8.4 5.4 6.4 7.2 0.1 2.9 2 1 1 3 3 3 0 SlyX APG6 PF04111.7 CCM04433.1 - 3.3 6.6 8.6 6.7 5.6 6.0 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 CCM04433.1 - 4.1 7.0 10.9 15 5.1 7.6 1.9 1 1 0 1 1 1 0 Mnd1 family DivIVA PF05103.8 CCM04433.1 - 5.9 6.9 9.5 1.9 8.5 3.7 2.1 2 1 0 2 2 2 0 DivIVA protein Spc24 PF08286.6 CCM04433.1 - 7.8 6.2 7.0 3.4 7.4 2.2 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 adh_short PF00106.20 CCM04434.1 - 1.5e-22 80.3 0.1 2.2e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04434.1 - 8.6e-12 45.0 0.0 4.9e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCM04434.1 - 0.00014 20.8 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF883 PF05957.8 CCM04435.1 - 0.044 14.1 10.7 3.6 8.0 0.8 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) CENP-F_leu_zip PF10473.4 CCM04435.1 - 0.11 12.3 0.4 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spiralin PF05215.8 CCM04435.1 - 0.14 11.2 5.7 0.18 10.8 3.5 1.4 1 1 0 1 1 1 0 Spiralin Mnd1 PF03962.10 CCM04435.1 - 0.16 11.6 4.1 0.18 11.4 2.8 1.2 1 0 0 1 1 1 0 Mnd1 family Prominin PF05478.6 CCM04435.1 - 0.33 8.4 2.5 0.41 8.1 1.7 1.0 1 0 0 1 1 1 0 Prominin Glyco_transf_8 PF01501.15 CCM04436.1 - 7.8e-33 113.8 0.0 1.2e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 ABC1 PF03109.11 CCM04437.1 - 3.4e-22 78.6 0.0 1.1e-20 73.7 0.0 2.4 1 1 0 1 1 1 1 ABC1 family Oxidored_FMN PF00724.15 CCM04438.1 - 1.8e-36 125.8 0.0 2.3e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ComA PF02679.10 CCM04438.1 - 0.0083 15.1 0.0 3.3 6.6 0.0 2.1 2 0 0 2 2 2 2 (2R)-phospho-3-sulfolactate synthase (ComA) Oxidored_FMN PF00724.15 CCM04439.1 - 2.1e-22 79.5 0.0 2.5e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fructosamin_kin PF03881.9 CCM04440.1 - 5.2e-63 212.7 0.0 6e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 CCM04440.1 - 2e-06 27.7 0.0 3.3e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RNA_pol_Rpb2_6 PF00562.23 CCM04441.1 - 1e-127 426.1 0.1 1.5e-127 425.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCM04441.1 - 1.1e-68 230.1 0.0 1.7e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCM04441.1 - 3.9e-47 160.1 0.3 7.8e-47 159.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCM04441.1 - 3e-29 101.0 0.0 6.7e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCM04441.1 - 8.3e-28 95.9 0.7 2.3e-27 94.5 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCM04441.1 - 2.3e-23 81.7 0.1 4.6e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCM04441.1 - 4.6e-21 74.5 0.2 1e-20 73.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MHC_II_alpha PF00993.15 CCM04441.1 - 0.062 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain Lung_7-TM_R PF06814.8 CCM04443.1 - 4.1e-61 206.5 14.8 4.9e-61 206.2 10.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PepSY_TM_2 PF13703.1 CCM04443.1 - 0.0043 17.1 13.8 0.2 11.8 5.4 3.3 2 1 1 3 3 3 2 PepSY-associated TM helix Oxidored_q2 PF00420.19 CCM04443.1 - 0.81 9.3 17.2 2.3 7.8 6.4 3.0 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PX PF00787.19 CCM04444.1 - 3.5e-18 65.4 0.3 1.3e-17 63.6 0.3 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CCM04444.1 - 0.00025 20.3 3.6 0.0015 17.8 0.9 2.9 1 1 2 3 3 3 1 Vps5 C terminal like HORMA PF02301.13 CCM04445.1 - 1.6e-19 70.2 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Fungal_trans PF04082.13 CCM04446.1 - 1.2e-35 122.6 2.1 1.9e-35 121.9 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM04446.1 - 4.7e-06 26.4 10.9 7.8e-06 25.7 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CWC25 PF12542.3 CCM04447.1 - 1.9e-25 89.1 2.0 1.9e-25 89.1 1.4 4.1 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 CCM04447.1 - 1.5e-12 47.2 13.0 1.5e-12 47.2 9.0 4.4 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Bac_luciferase PF00296.15 CCM04447.1 - 0.029 13.4 0.2 0.029 13.4 0.1 1.8 2 0 0 2 2 2 0 Luciferase-like monooxygenase Ion_trans PF00520.26 CCM04448.1 - 2.1e-05 23.8 2.6 2.1e-05 23.8 1.8 1.6 2 0 0 2 2 2 1 Ion transport protein SUR7 PF06687.7 CCM04448.1 - 0.0089 15.6 1.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 SUR7/PalI family MFS_3 PF05977.8 CCM04448.1 - 0.14 10.2 2.5 0.19 9.8 1.7 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector I_LWEQ PF01608.12 CCM04450.1 - 1.4e-62 210.1 8.3 1.4e-62 210.1 5.7 4.9 4 1 0 5 5 5 1 I/LWEQ domain ANTH PF07651.11 CCM04450.1 - 6.2e-56 189.1 3.6 4.8e-55 186.2 0.0 3.1 3 0 0 3 3 3 1 ANTH domain TcdB_N PF12918.2 CCM04450.1 - 0.0018 18.3 0.5 0.015 15.3 0.0 2.8 2 0 0 2 2 2 1 TcdB toxin N-terminal helical domain FAD_binding_4 PF01565.18 CCM04450.1 - 0.22 10.9 1.7 3.5 7.1 0.0 3.2 4 0 0 4 4 4 0 FAD binding domain SURF1 PF02104.10 CCM04451.1 - 3.1e-50 170.9 0.0 7.8e-50 169.6 0.0 1.6 1 0 0 1 1 1 1 SURF1 family Myb_DNA-binding PF00249.26 CCM04453.1 - 3.9e-08 33.2 0.0 7.6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCM04453.1 - 0.00069 19.6 0.5 0.005 16.9 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Peptidase_M15 PF01427.12 CCM04453.1 - 0.076 12.6 1.0 0.54 9.8 0.5 2.1 2 0 0 2 2 2 0 D-ala-D-ala dipeptidase Rad51 PF08423.6 CCM04454.1 - 2.5e-114 380.5 0.0 3.5e-114 380.0 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CCM04454.1 - 3.7e-12 46.0 0.0 5.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CCM04454.1 - 9.3e-12 44.6 0.3 1.3e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CCM04454.1 - 1.2e-06 27.7 0.7 2.1e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 KaiC HHH_5 PF14520.1 CCM04454.1 - 0.0082 16.2 0.1 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA PF00004.24 CCM04454.1 - 0.014 15.5 0.2 0.1 12.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCM04454.1 - 0.021 14.9 0.1 0.056 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_pol_A_CTD PF03118.10 CCM04454.1 - 0.023 14.0 0.1 0.05 13.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain HHH PF00633.18 CCM04454.1 - 0.031 13.9 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_3 PF12836.2 CCM04454.1 - 0.086 12.7 0.4 0.33 10.9 0.1 2.2 2 1 0 2 2 2 0 Helix-hairpin-helix motif EthD PF07110.6 CCM04455.1 - 1.9e-06 28.7 0.1 0.042 14.7 0.0 2.6 2 1 0 2 2 2 2 EthD domain DUF4286 PF14114.1 CCM04455.1 - 0.00052 20.2 0.4 0.71 10.1 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) ABM PF03992.11 CCM04455.1 - 0.0049 16.8 0.4 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Ribonuclease_T2 PF00445.13 CCM04456.1 - 2.4e-34 118.5 0.1 4e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family DREV PF05219.7 CCM04457.1 - 0.036 12.9 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Peptidase_M16 PF00675.15 CCM04458.1 - 1.5e-39 135.1 0.0 2.6e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCM04458.1 - 2.3e-34 118.6 0.0 1.6e-33 115.9 0.0 2.3 2 1 0 2 2 2 1 Peptidase M16 inactive domain BRCA-2_OB1 PF09103.5 CCM04459.1 - 9.4e-28 96.2 0.0 1.7e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 CCM04459.1 - 2e-07 30.7 0.2 4.1e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 BRCA2, helical Lum_binding PF00677.12 CCM04460.1 - 1.5e-28 98.5 0.0 8.5e-14 51.2 0.0 3.5 3 0 0 3 3 3 3 Lumazine binding domain Ino80_Iec3 PF14612.1 CCM04460.1 - 0.21 11.6 3.2 0.12 12.4 0.5 1.8 2 0 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling UDPGP PF01704.13 CCM04463.1 - 5.3e-52 176.7 0.0 6.9e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CCM04463.1 - 0.0055 16.8 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 MobA-like NTP transferase domain DUF4119 PF13494.1 CCM04463.1 - 0.018 15.0 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Taxilin PF09728.4 CCM04464.1 - 9e-13 47.9 35.0 3e-07 29.8 4.4 2.7 2 1 1 3 3 3 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.3 CCM04464.1 - 6.1e-07 29.0 0.4 0.012 15.2 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CCM04464.1 - 0.0033 16.7 0.6 0.08 12.3 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin family CorA PF01544.13 CCM04464.1 - 0.28 10.1 11.2 3.7 6.4 0.0 3.2 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF3070 PF11270.3 CCM04464.1 - 2.3 8.0 9.8 0.16 11.7 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3070) Ceramidase PF05875.7 CCM04465.1 - 7e-70 235.1 5.6 7.9e-70 234.9 3.9 1.0 1 0 0 1 1 1 1 Ceramidase Neurensin PF14927.1 CCM04465.1 - 0.033 13.5 0.8 10 5.4 0.0 3.3 3 0 0 3 3 3 0 Neurensin Myosin_head PF00063.16 CCM04466.1 - 1.3e-230 767.1 0.5 2.1e-230 766.4 0.3 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CCM04466.1 - 4.9e-45 153.3 0.0 7.8e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 Myosin tail SH3_2 PF07653.12 CCM04466.1 - 1.3e-09 37.4 0.0 2.9e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CCM04466.1 - 2.7e-09 36.4 0.2 5.9e-09 35.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCM04466.1 - 6.4e-08 31.8 0.9 1.3e-07 30.8 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 CCM04466.1 - 0.00032 20.8 0.9 0.001 19.1 0.6 1.9 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 CCM04466.1 - 0.0074 16.4 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCM04466.1 - 0.027 13.5 0.0 0.073 12.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 CCM04466.1 - 0.056 14.2 0.0 0.24 12.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCM04466.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Hpr_kinase_C PF07475.7 CCM04466.1 - 0.058 12.6 1.3 5 6.4 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 CCM04466.1 - 0.099 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CCM04466.1 - 0.16 11.9 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AMP-binding PF00501.23 CCM04467.1 - 4.8e-31 107.5 0.1 8e-30 103.5 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 CCM04467.1 - 8.1e-06 26.0 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site UNC45-central PF11701.3 CCM04468.1 - 8.4e-11 41.7 0.1 2.2e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Gcd10p PF04189.8 CCM04469.1 - 3.6e-70 236.4 0.0 1.9e-69 234.0 0.0 1.9 1 1 0 1 1 1 1 Gcd10p family UBX PF00789.15 CCM04469.1 - 0.11 12.5 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 UBX domain PXA PF02194.10 CCM04470.1 - 4.4e-42 143.7 0.2 3.9e-41 140.6 0.1 2.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 CCM04470.1 - 1.9e-32 111.6 0.1 1.9e-30 105.2 0.0 3.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 CCM04470.1 - 7.2e-18 64.4 0.2 4e-17 62.0 0.0 2.3 2 0 0 2 2 2 1 PX domain RGS PF00615.14 CCM04470.1 - 7.6e-09 35.7 0.1 3.6e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain GMC_oxred_N PF00732.14 CCM04471.1 - 2.2e-63 214.1 0.0 2.7e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM04471.1 - 3.2e-37 128.0 0.1 5.8e-37 127.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCM04471.1 - 2.9e-05 23.1 0.2 0.00052 18.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CCM04471.1 - 3.9e-05 22.7 0.1 0.00019 20.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCM04471.1 - 0.00063 19.7 0.7 0.0023 17.9 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 CCM04471.1 - 0.0075 16.2 0.1 0.025 14.6 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.22 CCM04471.1 - 0.018 15.4 0.1 0.046 14.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCM04471.1 - 0.021 13.9 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 CCM04471.1 - 0.028 13.2 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 CCM04471.1 - 0.036 13.9 0.1 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM04471.1 - 0.039 12.8 0.2 0.063 12.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CCM04471.1 - 0.16 11.9 0.0 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM04471.1 - 0.26 9.6 0.1 0.43 8.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Mito_carr PF00153.22 CCM04472.1 - 1.3e-43 146.5 0.3 7.3e-16 57.6 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein COesterase PF00135.23 CCM04473.1 - 4.9e-86 289.5 0.0 6.6e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM04473.1 - 7.8e-09 35.4 0.0 1.9e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM04473.1 - 0.0023 17.1 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCM04473.1 - 0.0077 15.9 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DAO PF01266.19 CCM04475.1 - 3.4e-23 82.1 2.8 1.4e-22 80.1 1.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCM04475.1 - 0.041 14.2 0.2 0.088 13.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCM04475.1 - 0.056 13.3 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCM04475.1 - 0.11 11.1 0.4 0.18 10.3 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Adeno_E4_34 PF04528.8 CCM04477.1 - 0.52 9.8 2.7 0.66 9.5 1.9 1.3 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Thr_synth_N PF14821.1 CCM04479.1 - 2.3e-27 94.7 0.0 6.6e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 CCM04479.1 - 7.4e-18 64.8 0.0 1.3e-17 64.0 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.27 CCM04480.1 - 8.8e-54 177.5 25.5 1.3e-10 40.7 0.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 CCM04480.1 - 2.8e-09 36.5 2.7 5.9e-09 35.5 1.9 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CCM04480.1 - 3.7e-09 35.2 0.6 0.0072 14.5 0.0 4.3 2 1 2 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 CCM04480.1 - 5.5e-07 29.0 2.6 1.4e-06 27.8 1.8 1.8 1 0 0 1 1 1 1 F-box domain NT-C2 PF10358.4 CCM04481.1 - 6.4e-18 64.6 0.0 4.9e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Iso_dh PF00180.15 CCM04482.1 - 1.4e-69 234.6 0.0 1.6e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SIR2 PF02146.12 CCM04483.1 - 9.6e-32 110.1 0.0 1e-30 106.8 0.0 2.3 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.11 CCM04483.1 - 0.0093 14.7 0.3 0.016 14.0 0.0 1.4 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.17 CCM04483.1 - 0.055 13.2 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Ribosomal_L28 PF00830.14 CCM04484.1 - 2.2e-23 81.8 1.4 3.2e-23 81.3 1.0 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Pkinase PF00069.20 CCM04485.1 - 4.6e-69 232.4 0.0 8.9e-69 231.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM04485.1 - 7.2e-30 103.9 0.0 1.1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM04485.1 - 1.1e-05 24.6 0.0 1.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCM04485.1 - 0.0014 17.7 0.1 0.0026 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM04485.1 - 0.0081 15.9 0.0 0.026 14.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CCM04485.1 - 0.035 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL P_C PF06640.6 CCM04488.1 - 0.35 10.8 2.6 0.18 11.7 0.2 1.6 2 0 0 2 2 2 0 P protein C-terminus TisB_toxin PF13939.1 CCM04489.1 - 0.15 11.8 0.2 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system PNP_UDP_1 PF01048.15 CCM04490.1 - 1e-36 126.1 0.4 1.3e-36 125.7 0.3 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2013 PF09431.5 CCM04492.1 - 8.2e-43 145.5 5.7 8.6e-43 145.4 0.3 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2013) PhzC-PhzF PF02567.11 CCM04493.1 - 5.1e-36 124.3 0.0 8.7e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein BPD_transp_2 PF02653.11 CCM04493.1 - 0.029 13.3 0.2 0.05 12.5 0.1 1.3 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component BTB PF00651.26 CCM04494.1 - 2.9e-08 33.6 0.0 5.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-ISL3 PF14690.1 CCM04494.1 - 0.053 13.5 0.1 0.87 9.6 0.0 2.7 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 AAA_4 PF04326.9 CCM04494.1 - 0.06 13.4 0.0 0.47 10.6 0.0 2.3 2 1 0 2 2 2 0 Divergent AAA domain DUF3669 PF12417.3 CCM04494.1 - 0.12 12.1 0.1 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Zinc finger protein Glucan_synthase PF02364.10 CCM04495.1 - 0 1362.2 0.0 0 1361.8 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCM04495.1 - 1.1e-38 131.7 0.0 3.6e-38 130.0 0.0 1.9 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Asp PF00026.18 CCM04495.1 - 1.1e-21 77.4 0.1 2.5e-21 76.2 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic aspartyl protease Velvet PF11754.3 CCM04496.1 - 1.8e-22 79.9 0.0 2.6e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 Velvet factor UQ_con PF00179.21 CCM04497.1 - 3.6e-45 152.8 0.0 4.2e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCM04497.1 - 1.6e-08 34.3 0.1 9.2e-07 28.6 0.0 2.0 1 1 1 2 2 2 2 Prokaryotic E2 family B Nup54 PF13874.1 CCM04498.1 - 1.2e-34 119.0 1.6 2.2e-34 118.1 1.1 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 WD40 PF00400.27 CCM04498.1 - 4.5e-30 102.4 0.1 1.5e-08 34.2 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_FG PF13634.1 CCM04498.1 - 4.6e-25 88.0 211.5 3.9e-08 33.5 32.0 7.2 2 2 4 6 6 6 5 Nucleoporin FG repeat region eIF2A PF08662.6 CCM04498.1 - 0.0042 16.8 0.0 0.23 11.1 0.0 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 CCM04498.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region eIF-5_eIF-2B PF01873.12 CCM04499.1 - 8.9e-46 154.6 0.2 1.3e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 CCM04499.1 - 0.0091 15.2 0.4 0.024 13.9 0.3 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding XPC-binding PF09280.6 CCM04499.1 - 0.091 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 XPC-binding domain CPSF100_C PF13299.1 CCM04499.1 - 0.12 12.5 0.7 0.2 11.8 0.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ykof PF07615.6 CCM04499.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 YKOF-related Family zf-HYPF PF07503.7 CCM04499.1 - 2.8 7.4 8.7 4.8 6.6 0.0 3.1 4 0 0 4 4 4 0 HypF finger ATP-synt PF00231.14 CCM04500.1 - 3.3e-74 249.8 6.8 3.8e-74 249.6 4.7 1.0 1 0 0 1 1 1 1 ATP synthase DNA_Packaging PF11053.3 CCM04500.1 - 0.072 12.7 0.2 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Terminase DNA packaging enzyme BRO1 PF03097.13 CCM04501.1 - 6.3e-113 377.3 1.0 1.2e-112 376.3 0.7 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCM04501.1 - 3.5e-59 200.1 7.0 6.4e-59 199.3 4.9 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Catalase PF00199.14 CCM04502.1 - 3.1e-141 470.5 0.9 7.8e-141 469.1 0.6 1.5 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCM04502.1 - 3.1e-16 58.9 0.0 9.4e-16 57.4 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive TB2_DP1_HVA22 PF03134.14 CCM04503.1 - 1.5e-26 91.9 8.4 2.1e-26 91.4 5.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Pheromone PF08015.6 CCM04503.1 - 1.3 9.9 6.2 4.3 8.2 4.3 2.0 1 0 0 1 1 1 0 Fungal mating-type pheromone Ferritin_2 PF13668.1 CCM04504.1 - 9.5e-39 132.4 0.0 1.4e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.1 CCM04505.1 - 7.3e-40 136.0 0.0 1.1e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Cerato-platanin PF07249.7 CCM04506.1 - 4.3e-44 149.3 1.9 5.5e-44 148.9 1.3 1.0 1 0 0 1 1 1 1 Cerato-platanin POC1 PF10450.4 CCM04506.1 - 0.041 12.6 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 POC1 chaperone HMG_box PF00505.14 CCM04507.1 - 7.9e-13 48.4 3.0 1.5e-12 47.6 2.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM04507.1 - 8e-06 26.1 1.0 1.4e-05 25.3 0.7 1.4 1 0 0 1 1 1 1 HMG-box domain RSN1_TM PF13967.1 CCM04508.1 - 0.14 11.6 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Vpu PF00558.14 CCM04508.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Vpu protein ADH_N PF08240.7 CCM04509.1 - 1.2e-26 92.6 3.3 1.8e-26 91.9 2.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM04509.1 - 4.8e-19 68.1 0.0 8.7e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM04509.1 - 2.4e-05 25.2 0.0 3.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCM04509.1 - 6.3e-05 22.2 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CCM04509.1 - 0.00026 20.5 0.0 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CCM04509.1 - 0.0061 16.4 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ELFV_dehydrog PF00208.16 CCM04509.1 - 0.045 13.3 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 CCM04509.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain E1-E2_ATPase PF00122.15 CCM04510.1 - 4e-60 202.7 5.0 7.6e-60 201.7 3.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCM04510.1 - 2.6e-25 90.1 0.0 7e-25 88.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CCM04510.1 - 5.8e-24 84.6 17.4 4.9e-18 65.3 0.8 4.2 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 CCM04510.1 - 1.9e-19 69.3 0.0 4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCM04510.1 - 2e-15 55.9 0.0 4.2e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CCM04510.1 - 8.5e-11 42.3 0.0 2.6e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCM04510.1 - 0.00017 21.2 0.6 0.026 14.0 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Rpp20 PF12328.3 CCM04511.1 - 2.7e-05 23.8 0.0 0.0051 16.4 0.0 3.0 3 1 1 4 4 4 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 CCM04511.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Alba Prok-E2_B PF14461.1 CCM04511.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF605 PF04652.11 CCM04511.1 - 3.8 6.8 8.5 5 6.4 5.9 1.1 1 0 0 1 1 1 0 Vta1 like eRF1_2 PF03464.10 CCM04512.1 - 1.3e-45 155.0 0.1 2.7e-45 153.9 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCM04512.1 - 4.7e-39 133.1 0.4 9.5e-39 132.1 0.3 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CCM04512.1 - 6.5e-27 93.7 0.0 1.4e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Phosducin PF02114.11 CCM04513.1 - 3.7e-05 22.6 0.0 6.1e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Phosducin MRI PF15325.1 CCM04513.1 - 1.2 10.1 5.0 1.6 9.7 1.7 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection p450 PF00067.17 CCM04514.1 - 1.5e-80 271.0 0.0 1.9e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 CCM04514.1 - 6e-31 107.6 0.0 9.4e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCM04514.1 - 4.6e-15 55.8 1.5 3.1e-11 43.4 0.1 2.9 2 1 1 3 3 3 2 Flavodoxin NAD_binding_1 PF00175.16 CCM04514.1 - 1.1e-09 38.8 0.0 2.9e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ribonuclease_3 PF00636.21 CCM04515.1 - 7.3e-40 135.9 0.0 1.6e-20 73.6 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCM04515.1 - 7.7e-31 106.7 0.2 3.6e-16 59.2 0.0 4.0 3 1 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 CCM04515.1 - 9.2e-15 54.5 0.0 2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM04515.1 - 3.5e-14 52.4 0.0 8.1e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM04515.1 - 4.5e-14 52.6 0.0 1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.9 CCM04515.1 - 5.9e-10 38.7 0.0 1.6e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain CMD PF02627.15 CCM04516.1 - 0.00034 20.3 0.0 0.0061 16.3 0.0 2.4 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family RRM_1 PF00076.17 CCM04517.1 - 3.3e-34 116.3 0.0 1.6e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04517.1 - 3.2e-17 62.2 0.0 1.1e-08 34.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM04517.1 - 1.4e-09 37.6 0.0 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CCM04517.1 - 0.049 13.1 0.3 0.47 9.9 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 CCM04517.1 - 0.15 11.8 0.0 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 F-box-like PF12937.2 CCM04520.1 - 1.9e-08 33.8 2.0 4.3e-08 32.7 1.4 1.7 1 0 0 1 1 1 1 F-box-like Glycos_transf_1 PF00534.15 CCM04521.1 - 6.4e-21 74.5 0.0 9.3e-14 51.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCM04521.1 - 6.5e-14 52.3 0.3 6.3e-13 49.1 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CCM04521.1 - 3.2e-10 39.9 0.0 1.8e-09 37.5 0.1 2.2 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CCM04521.1 - 1.6e-05 25.0 0.0 6.7e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CCM04521.1 - 0.0047 17.1 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3768 PF12599.3 CCM04522.1 - 0.09 12.7 0.1 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3768) DUF4251 PF14059.1 CCM04522.1 - 0.11 12.3 0.1 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4251) Corona_nucleoca PF00937.13 CCM04523.1 - 3.5 6.5 9.6 5 5.9 6.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3984 PF13136.1 CCM04523.1 - 7.6 5.6 13.5 19 4.3 7.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) FA_desaturase PF00487.19 CCM04524.1 - 6.4e-27 94.6 27.6 1.4e-26 93.4 19.2 1.5 1 1 0 1 1 1 1 Fatty acid desaturase UPF0158 PF03682.8 CCM04525.1 - 0.061 12.9 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF2947 PF11163.3 CCM04525.1 - 0.069 12.7 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) DUF1014 PF06244.7 CCM04526.1 - 7.1e-23 81.1 23.4 7.8e-22 77.7 16.2 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Allexi_40kDa PF05549.6 CCM04526.1 - 0.3 10.3 2.0 0.37 10.0 0.0 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein FRG1 PF06229.7 CCM04526.1 - 1.5 8.2 12.3 11 5.4 7.5 2.4 2 0 0 2 2 2 0 FRG1-like family DUF2639 PF11121.3 CCM04526.1 - 3.1 7.3 4.7 2.3 7.7 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2639) Ycf1 PF05758.7 CCM04526.1 - 4.9 4.7 8.2 5 4.6 5.7 1.1 1 0 0 1 1 1 0 Ycf1 Calcipressin PF04847.7 CCM04527.1 - 8.8e-35 119.9 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Calcipressin DUF4381 PF14316.1 CCM04529.1 - 0.078 13.0 2.6 0.14 12.2 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ras PF00071.17 CCM04530.1 - 2.2e-63 212.4 0.3 2.6e-63 212.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM04530.1 - 9.2e-20 71.3 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM04530.1 - 4e-16 58.7 0.0 5.4e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCM04530.1 - 1.8e-06 27.2 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCM04530.1 - 3.6e-05 23.2 0.1 8e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCM04530.1 - 0.00014 21.8 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCM04530.1 - 0.00057 19.1 0.0 0.00072 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCM04530.1 - 0.0068 16.5 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCM04530.1 - 0.0085 16.0 0.1 0.021 14.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 CCM04530.1 - 0.012 14.8 0.0 0.05 12.8 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 CCM04530.1 - 0.02 15.1 0.1 0.48 10.6 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCM04530.1 - 0.041 13.0 0.0 0.082 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 CCM04530.1 - 0.043 13.5 0.0 0.066 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CCM04530.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 CCM04530.1 - 0.48 9.0 2.4 8.1 5.0 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA PF00004.24 CCM04531.1 - 7.6e-43 145.8 0.0 1.4e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCM04531.1 - 4.5e-08 33.2 0.0 1.9e-05 24.7 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CCM04531.1 - 4.9e-07 29.5 0.1 7e-06 25.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCM04531.1 - 4.4e-06 26.7 0.0 2.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCM04531.1 - 8.5e-06 25.9 0.0 0.00076 19.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCM04531.1 - 8.5e-06 24.9 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCM04531.1 - 5.9e-05 22.7 0.8 0.00025 20.7 0.6 2.0 1 1 1 2 2 2 1 Part of AAA domain DUF815 PF05673.8 CCM04531.1 - 0.001 18.0 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CCM04531.1 - 0.0011 19.7 0.2 0.0031 18.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCM04531.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCM04531.1 - 0.0022 17.4 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCM04531.1 - 0.0024 16.9 0.3 0.0089 15.1 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 CCM04531.1 - 0.0028 16.8 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCM04531.1 - 0.0028 17.5 0.0 0.009 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCM04531.1 - 0.0031 17.6 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CCM04531.1 - 0.0046 15.7 0.0 0.0084 14.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 CCM04531.1 - 0.0057 16.9 0.1 0.024 14.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 CCM04531.1 - 0.0069 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CCM04531.1 - 0.0073 15.5 0.1 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein Sigma54_activat PF00158.21 CCM04531.1 - 0.0095 15.4 0.0 0.033 13.6 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 CCM04531.1 - 0.011 15.1 0.3 0.071 12.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CCM04531.1 - 0.013 15.1 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CCM04531.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CCM04531.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CCM04531.1 - 0.018 15.3 0.1 5.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CCM04531.1 - 0.028 14.1 0.0 0.11 12.1 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.1 CCM04531.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 CCM04531.1 - 0.056 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 CCM04531.1 - 0.056 12.5 0.7 0.16 11.0 0.0 2.1 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 CCM04531.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 CCM04531.1 - 0.095 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TPR_MLP1_2 PF07926.7 CCM04531.1 - 0.1 12.3 0.3 0.1 12.3 0.2 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_11 PF13086.1 CCM04531.1 - 0.18 11.3 0.6 0.38 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF4140 PF13600.1 CCM04531.1 - 0.23 11.9 1.6 0.35 11.3 0.2 2.0 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.1 CCM04531.1 - 0.37 10.7 5.6 0.055 13.4 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IMS PF00817.15 CCM04532.1 - 6.6e-41 139.5 0.1 1.3e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CCM04532.1 - 5.2e-18 65.1 0.0 1.4e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CCM04532.1 - 5.5e-06 26.1 0.0 1.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif PTCB-BRCT PF12738.2 CCM04532.1 - 0.00011 21.9 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 CCM04532.1 - 0.0014 18.7 0.0 0.0047 17.0 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4414 PF14377.1 CCM04532.1 - 0.024 14.5 0.0 5 7.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) DUF1805 PF08827.6 CCM04532.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Methyltransf_23 PF13489.1 CCM04533.1 - 5e-17 62.0 0.0 1.1e-16 60.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM04533.1 - 4.7e-13 49.4 0.0 8.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM04533.1 - 4.9e-13 48.9 0.0 6.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM04533.1 - 1.2e-11 44.9 0.0 2.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM04533.1 - 1.5e-09 38.4 0.0 1e-08 35.7 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM04533.1 - 4.4e-07 30.2 0.2 9.7e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM04533.1 - 1.8e-05 24.7 0.0 4.8e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM04533.1 - 2.4e-05 23.5 0.0 8.5e-05 21.7 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 CCM04533.1 - 0.042 12.8 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF433 PF04255.9 CCM04533.1 - 0.23 10.9 0.6 18 4.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF433) p450 PF00067.17 CCM04534.1 - 3.7e-58 197.1 0.0 9.1e-51 172.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 CCM04535.1 - 5.7e-63 213.0 0.0 8.1e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 CCM04535.1 - 3.1e-36 124.8 25.0 3.1e-36 124.8 17.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM04535.1 - 8.9e-07 27.8 6.0 8.9e-07 27.8 4.2 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter Ubie_methyltran PF01209.13 CCM04536.1 - 0.00025 20.2 0.2 0.00052 19.2 0.2 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Sir1 PF11603.3 CCM04536.1 - 0.019 15.1 0.6 0.06 13.5 0.2 1.8 2 0 0 2 2 2 0 Regulatory protein Sir1 Flavodoxin_1 PF00258.20 CCM04536.1 - 0.029 14.3 0.0 0.1 12.6 0.0 1.9 1 1 0 1 1 1 0 Flavodoxin Phage_Gp19 PF09355.5 CCM04536.1 - 0.073 12.9 0.3 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Aegerolysin PF06355.8 CCM04537.1 - 1.5e-48 164.0 0.2 1.8e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 Aegerolysin Glyco_hydro_31 PF01055.21 CCM04538.1 - 5.6e-151 503.3 1.7 7.2e-151 502.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCM04538.1 - 5.9e-10 38.8 0.2 2.2e-09 37.0 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Myb_DNA-bind_2 PF08914.6 CCM04539.1 - 7.7e-18 64.0 9.3 1.2e-10 41.0 2.6 2.9 2 0 0 2 2 2 2 Rap1 Myb domain GP41 PF00517.12 CCM04539.1 - 4.3 6.8 7.5 0.63 9.5 1.8 1.8 2 0 0 2 2 2 0 Retroviral envelope protein Rap1-DNA-bind PF09197.5 CCM04539.1 - 5.3 7.6 11.6 3.6 8.1 0.6 3.6 3 0 0 3 3 3 0 Rap1, DNA-binding Pkinase PF00069.20 CCM04540.1 - 5e-45 153.6 0.0 6.8e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM04540.1 - 8e-26 90.6 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM04540.1 - 0.0033 16.4 0.0 0.0073 15.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCM04540.1 - 0.049 13.3 0.4 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Asp-B-Hydro_N PF05279.6 CCM04542.1 - 4.1 7.1 11.4 4.9 6.9 7.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FLO_LFY PF01698.11 CCM04542.1 - 4.5 6.0 12.3 5.5 5.7 8.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4557 PF15101.1 CCM04542.1 - 6.6 6.5 9.3 8.4 6.1 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) HOASN PF14515.1 CCM04542.1 - 7.5 7.0 7.5 5.2 7.5 3.0 2.0 1 1 1 2 2 2 0 Haem-oxygenase-associated N-terminal helices Shugoshin_C PF07557.6 CCM04543.1 - 1.5e-09 37.1 2.3 1.5e-09 37.1 1.6 3.6 3 0 0 3 3 3 1 Shugoshin C terminus Shugoshin_N PF07558.6 CCM04543.1 - 3.6e-05 23.3 2.2 8.1e-05 22.2 1.6 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Rtf2 PF04641.7 CCM04543.1 - 0.64 9.1 7.6 1.3 8.1 5.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Myb_DNA-bind_2 PF08914.6 CCM04544.1 - 0.0061 16.3 0.8 0.021 14.5 0.6 2.0 1 1 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 CCM04544.1 - 0.12 12.9 2.2 0.57 10.7 1.5 2.1 1 1 0 1 1 1 0 Rap1, DNA-binding MFS_1 PF07690.11 CCM04545.1 - 6e-43 146.9 42.4 1.7e-40 138.8 30.5 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCM04545.1 - 2.3e-08 32.7 11.8 2.5e-08 32.5 7.9 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCM04545.1 - 7.9e-07 27.9 11.6 7.9e-07 27.9 8.0 3.9 2 2 2 4 4 4 2 Sugar (and other) transporter Cyclase PF04199.8 CCM04546.1 - 4.5e-15 55.7 0.0 6.2e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Aegerolysin PF06355.8 CCM04547.1 - 4.9e-47 159.0 1.2 6.6e-47 158.6 0.9 1.2 1 0 0 1 1 1 1 Aegerolysin Imm15 PF15590.1 CCM04547.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 15 Ubie_methyltran PF01209.13 CCM04548.1 - 0.0001 21.4 0.3 0.00023 20.3 0.2 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Sir1 PF11603.3 CCM04548.1 - 0.021 14.9 0.3 0.049 13.7 0.2 1.5 1 0 0 1 1 1 0 Regulatory protein Sir1 Cyclase PF04199.8 CCM04549.1 - 6.4e-15 55.2 0.0 1.1e-14 54.4 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase Pkinase PF00069.20 CCM04550.1 - 4.4e-50 170.2 0.0 6.6e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM04550.1 - 4.1e-24 85.0 0.0 9.6e-24 83.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CCM04550.1 - 0.0049 16.2 0.4 1.1 8.5 0.0 2.8 1 1 0 2 2 2 2 RIO1 family Pox_ser-thr_kin PF05445.6 CCM04550.1 - 0.011 14.6 0.1 0.011 14.6 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase p450 PF00067.17 CCM04551.1 - 5.3e-45 153.8 0.0 7.1e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.19 CCM04552.1 - 1.2e-16 60.9 19.6 1.2e-16 60.9 13.6 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCM04552.1 - 6.2e-15 54.7 0.0 1.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PP2C PF00481.16 CCM04553.1 - 1.4e-30 106.5 0.0 2.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CCM04553.1 - 1.7e-05 24.6 0.1 0.0012 18.6 0.0 3.0 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CCM04553.1 - 0.00022 20.6 0.0 0.00086 18.7 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C DUF1408 PF07193.6 CCM04555.1 - 0.088 12.3 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) ABC2_membrane PF01061.19 CCM04556.1 - 1.6e-73 246.3 59.3 1.8e-42 144.8 14.5 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 CCM04556.1 - 1.5e-36 125.6 0.0 2.4e-17 63.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCM04556.1 - 1.1e-31 108.5 10.1 1.7e-29 101.4 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.1 CCM04556.1 - 1.6e-07 30.9 0.0 0.0033 16.8 0.0 3.6 4 0 0 4 4 4 2 AAA domain ABC_trans_N PF14510.1 CCM04556.1 - 5.1e-07 29.7 0.1 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_22 PF13401.1 CCM04556.1 - 2.1e-06 27.9 0.0 0.06 13.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCM04556.1 - 3.5e-06 26.3 0.0 5.1e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCM04556.1 - 5.9e-06 26.4 0.4 0.01 15.8 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 CCM04556.1 - 0.00036 20.2 0.0 0.41 10.2 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.1 CCM04556.1 - 0.00045 19.6 0.9 0.046 13.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 CCM04556.1 - 0.00077 18.9 0.1 0.71 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 CCM04556.1 - 0.00087 18.8 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 CCM04556.1 - 0.00093 20.0 0.0 0.2 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CCM04556.1 - 0.0018 17.7 0.2 0.049 13.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CCM04556.1 - 0.0036 17.1 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCM04556.1 - 0.0046 17.2 0.0 0.56 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 CCM04556.1 - 0.0056 15.7 51.3 0.033 13.2 17.1 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein MMR_HSR1 PF01926.18 CCM04556.1 - 0.0066 16.3 0.0 1.7 8.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CCM04556.1 - 0.0092 15.7 0.2 1.7 8.4 0.2 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_21 PF13304.1 CCM04556.1 - 0.017 15.0 0.0 0.63 9.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 CCM04556.1 - 0.019 14.4 0.3 1.2 8.5 0.1 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CCM04556.1 - 0.023 13.7 0.0 6 5.7 0.0 2.2 2 0 0 2 2 2 0 Septin UPF0079 PF02367.12 CCM04556.1 - 0.024 14.2 0.2 0.46 10.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 CCM04556.1 - 0.046 14.2 0.0 13 6.3 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein SMC_N PF02463.14 CCM04556.1 - 0.055 12.6 0.0 2.9 7.0 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CCM04556.1 - 0.057 13.3 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CCM04556.1 - 0.12 12.5 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 CCM04556.1 - 0.14 11.7 0.3 4.4 6.8 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 CCM04556.1 - 0.15 12.2 0.0 8.1 6.6 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CCM04556.1 - 0.21 11.5 0.2 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCM04556.1 - 0.27 11.5 0.2 0.51 10.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain ketoacyl-synt PF00109.21 CCM04557.1 - 7.7e-47 159.9 2.6 1.4e-46 159.0 0.3 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CCM04557.1 - 1.8e-41 142.5 0.0 4.7e-41 141.1 0.0 1.7 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 CCM04557.1 - 1.6e-27 95.6 1.1 3.4e-27 94.6 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 CCM04557.1 - 6.2e-23 81.3 0.0 1.3e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 CCM04557.1 - 2.2e-18 66.5 0.1 1.1e-16 61.0 0.0 2.5 2 0 0 2 2 2 1 KR domain Thioesterase PF00975.15 CCM04557.1 - 5.1e-18 66.1 0.0 1e-17 65.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain adh_short PF00106.20 CCM04557.1 - 4.1e-17 62.6 0.2 1.9e-16 60.4 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.7 CCM04557.1 - 6.2e-13 49.0 0.0 1.7e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM04557.1 - 6.7e-12 45.4 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM04557.1 - 8.1e-08 31.9 0.0 2.6e-07 30.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM04557.1 - 1.1e-07 32.1 0.0 8.5e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 CCM04557.1 - 3.8e-07 30.2 0.0 9.5e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 CCM04557.1 - 4.2e-05 24.1 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 CCM04557.1 - 0.00023 20.2 0.0 0.00053 19.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 CCM04557.1 - 0.00027 20.5 2.4 0.0015 18.1 0.8 2.9 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.21 CCM04557.1 - 0.0042 16.6 0.0 0.29 10.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 CCM04557.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CCM04557.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-RING_2 PF13639.1 CCM04557.1 - 0.15 11.8 0.0 0.45 10.3 0.0 1.7 1 0 0 1 1 1 0 Ring finger domain DUF2974 PF11187.3 CCM04557.1 - 0.47 9.7 0.2 3.2 7.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Epimerase PF01370.16 CCM04558.1 - 9.3e-68 228.1 0.1 1.2e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CCM04558.1 - 1.7e-05 23.8 0.0 2.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CCM04558.1 - 0.0091 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CCM04558.1 - 0.045 12.9 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 CCM04558.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding Epimerase_Csub PF13950.1 CCM04558.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Pro_Al_protease PF02983.9 CCM04558.1 - 0.15 12.0 1.0 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Alpha-lytic protease prodomain zf-MYND PF01753.13 CCM04559.1 - 1.1e-08 34.7 7.6 2.1e-08 33.8 5.3 1.5 1 0 0 1 1 1 1 MYND finger Cellulase PF00150.13 CCM04560.1 - 2.7e-12 46.5 0.2 2.9e-08 33.2 0.1 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 CCM04560.1 - 0.089 12.1 0.1 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Lipase_3 PF01764.20 CCM04561.1 - 5.2e-07 29.3 0.2 5.8e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CCM04561.1 - 0.043 13.5 0.1 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 CCM04561.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 CCM04561.1 - 0.085 12.4 0.1 0.19 11.2 0.1 1.5 2 0 0 2 2 2 0 PGAP1-like protein eIF2A PF08662.6 CCM04562.1 - 2.5e-74 249.1 0.0 2.3e-72 242.7 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CCM04562.1 - 0.008 16.0 0.6 0.62 10.0 0.1 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Proteasome_A_N PF10584.4 CCM04562.1 - 0.024 13.9 8.3 1.9 7.9 0.0 4.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature CDV3 PF15359.1 CCM04562.1 - 0.68 10.0 6.8 0.2 11.7 1.8 2.3 2 1 1 3 3 3 0 Carnitine deficiency-associated protein 3 ORC6 PF05460.8 CCM04562.1 - 1.2 8.1 6.0 2 7.4 4.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) OPA3 PF07047.7 CCM04563.1 - 3.8e-08 33.1 0.3 7.4e-08 32.2 0.0 1.5 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) Dor1 PF04124.7 CCM04563.1 - 0.044 12.2 1.5 0.059 11.8 1.1 1.1 1 0 0 1 1 1 0 Dor1-like family HLH PF00010.21 CCM04563.1 - 0.068 12.8 0.5 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain NYD-SP28 PF14772.1 CCM04563.1 - 0.07 13.2 7.1 0.098 12.7 4.9 1.2 1 0 0 1 1 1 0 Sperm tail IncA PF04156.9 CCM04563.1 - 0.084 12.4 2.1 0.11 12.0 1.4 1.2 1 0 0 1 1 1 0 IncA protein L31 PF09784.4 CCM04563.1 - 0.11 12.6 0.3 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 RIC3 PF15361.1 CCM04563.1 - 0.27 11.4 2.5 0.48 10.6 0.1 2.0 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 FlxA PF14282.1 CCM04563.1 - 0.85 9.6 9.9 0.039 13.9 3.2 1.4 2 0 0 2 2 2 0 FlxA-like protein IPK PF03770.11 CCM04564.1 - 2.2e-40 138.3 0.0 1.6e-39 135.6 0.0 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase CobT PF06213.7 CCM04564.1 - 0.04 13.0 17.4 0.062 12.4 12.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 CCM04564.1 - 0.1 11.9 11.7 0.15 11.3 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 CCM04564.1 - 0.17 10.7 0.9 0.25 10.1 0.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CENP-T PF15511.1 CCM04564.1 - 0.22 10.7 7.2 0.31 10.2 5.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Tim54 PF11711.3 CCM04564.1 - 0.25 9.8 1.8 0.37 9.3 1.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2201_N PF13203.1 CCM04564.1 - 0.38 9.8 3.4 0.58 9.2 2.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain SDA1 PF05285.7 CCM04564.1 - 1.7 7.8 23.2 2.5 7.2 16.1 1.2 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.8 CCM04564.1 - 3.1 7.5 18.3 4.4 7.1 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.6 CCM04564.1 - 4.3 5.3 6.9 5.5 4.9 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC73 PF05179.9 CCM04565.1 - 1.1e-53 182.3 0.9 1.5e-53 181.8 0.6 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family RhoGEF PF00621.15 CCM04566.1 - 1.1e-43 149.2 1.1 1.8e-43 148.4 0.8 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 CCM04566.1 - 3.7e-21 74.2 0.5 4.8e-12 45.0 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CCM04566.1 - 1.5e-19 69.3 2.9 9.3e-09 34.7 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.2 CCM04566.1 - 5e-17 61.5 0.0 1.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 CCM04566.1 - 7.6e-12 44.5 0.0 2.3e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 CCM04566.1 - 3.6e-09 35.9 0.5 1.1e-08 34.3 0.4 1.9 1 0 0 1 1 1 1 WH2 motif PH PF00169.24 CCM04566.1 - 1e-05 25.6 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.1 CCM04566.1 - 5e-05 23.3 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CCM04566.1 - 0.00018 20.5 0.0 0.099 12.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CCM04566.1 - 0.0055 16.4 0.0 3.8 7.6 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain RestrictionMunI PF11407.3 CCM04566.1 - 0.04 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme MunI EF-hand_8 PF13833.1 CCM04566.1 - 0.046 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair SUV3_C PF12513.3 CCM04569.1 - 9e-15 53.8 0.0 2e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CCM04569.1 - 1.2e-09 37.9 0.1 3.5e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MRP-S33 PF08293.6 CCM04570.1 - 2.1e-23 82.1 0.1 4.4e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 p450 PF00067.17 CCM04571.1 - 2.6e-10 39.4 0.2 5.1e-10 38.4 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 tRNA-synt_1b PF00579.20 CCM04572.1 - 8.5e-73 245.0 0.0 1e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Mak10 PF04112.8 CCM04573.1 - 2.7e-34 117.8 0.0 4.4e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase HhH-GPD PF00730.20 CCM04574.1 - 6.8e-44 148.5 0.0 3.9e-22 78.5 0.0 2.4 2 0 0 2 2 2 2 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCM04574.1 - 5.5e-18 63.5 0.0 1.7e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 CCM04574.1 - 3.2e-07 30.4 0.4 0.16 12.1 0.0 3.9 4 0 0 4 4 4 2 Helix-hairpin-helix domain HHH_2 PF12826.2 CCM04574.1 - 0.13 12.1 0.0 22 5.0 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Phos_pyr_kin PF08543.7 CCM04575.1 - 1.5e-81 273.2 1.3 4.7e-80 268.3 0.9 2.1 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CCM04575.1 - 1.5e-45 155.5 0.0 2.2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CCM04575.1 - 0.0012 18.0 0.1 0.012 14.8 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RTA1 PF04479.8 CCM04576.1 - 5e-45 153.7 4.7 6.3e-45 153.3 3.3 1.1 1 0 0 1 1 1 1 RTA1 like protein FBPase PF00316.15 CCM04577.1 - 1.3e-129 431.7 0.0 1.4e-129 431.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CCM04577.1 - 0.00019 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family RdRP PF05183.7 CCM04578.1 - 1.3e-150 502.9 0.0 1.9e-150 502.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Pmp3 PF01679.12 CCM04579.1 - 3.2e-16 58.7 5.6 4.2e-16 58.3 3.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.3 CCM04579.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal PNGaseA PF12222.3 CCM04580.1 - 9.2e-82 275.1 8.3 1.4e-81 274.6 5.8 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A HTH_45 PF14947.1 CCM04580.1 - 0.011 15.5 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix FTHFS PF01268.14 CCM04581.1 - 1.3e-257 855.3 0.4 1.7e-257 854.8 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CCM04581.1 - 1.4e-67 225.8 0.2 4.2e-67 224.2 0.1 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCM04581.1 - 5.7e-34 116.6 0.5 1.6e-33 115.2 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GrpE PF01025.14 CCM04582.1 - 9.5e-45 152.1 0.1 1.3e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 GrpE tRNA-synt_2d PF01409.15 CCM04583.1 - 5e-46 156.9 0.0 1.1e-26 93.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CCM04583.1 - 1.8e-22 79.3 0.0 3.5e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain His_Phos_2 PF00328.17 CCM04583.1 - 0.16 11.2 0.1 0.26 10.5 0.1 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) GCIP PF13324.1 CCM04584.1 - 1.2e-07 31.2 0.0 2.6e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting RRM_1 PF00076.17 CCM04585.1 - 2.2e-05 23.9 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CCM04585.1 - 6.8e-05 22.4 2.7 0.0002 20.9 1.9 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CCM04585.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.1 CCM04585.1 - 0.022 14.7 1.8 0.056 13.4 1.2 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type RRM_6 PF14259.1 CCM04585.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RTA1 PF04479.8 CCM04586.1 - 5.2e-16 58.8 3.2 6.4e-16 58.5 2.2 1.0 1 0 0 1 1 1 1 RTA1 like protein ThiF PF00899.16 CCM04587.1 - 8.7e-39 132.4 0.1 3.2e-38 130.6 0.0 1.8 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 CCM04587.1 - 3.3e-25 87.6 0.3 5.4e-25 86.9 0.2 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 CCM04587.1 - 5.4e-19 67.5 0.3 1.3e-18 66.2 0.2 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCM04587.1 - 5.9e-18 63.9 1.5 1.2e-17 62.9 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CCM04587.1 - 0.0025 17.9 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 CCM04587.1 - 0.0048 16.4 0.4 0.041 13.4 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain ApbA PF02558.11 CCM04587.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 CCM04587.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UAE_UbL PF14732.1 CCM04587.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain RTC PF01137.16 CCM04588.1 - 3e-65 219.2 0.0 3.7e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CCM04588.1 - 2.9e-34 117.1 0.0 4.4e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain NPR2 PF06218.6 CCM04589.1 - 2.8e-96 322.8 0.0 3.7e-79 266.4 0.0 2.4 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 CCM04589.1 - 0.0033 16.0 0.3 0.059 11.8 0.1 2.0 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 ketoacyl-synt PF00109.21 CCM04590.1 - 1.4e-57 195.1 1.6 2.9e-57 194.0 1.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CCM04590.1 - 5.1e-40 137.7 0.0 1.1e-39 136.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 CCM04590.1 - 3.2e-36 124.6 0.0 8.1e-36 123.3 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CCM04590.1 - 4.2e-32 111.3 0.8 2.3e-31 108.9 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 CCM04590.1 - 3.1e-27 94.7 0.2 6.8e-27 93.6 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 CCM04590.1 - 1.7e-23 83.2 0.0 3.3e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 CCM04590.1 - 1.3e-19 71.3 0.0 3.4e-19 69.9 0.0 1.7 2 0 0 2 2 1 1 Thioesterase domain Methyltransf_23 PF13489.1 CCM04590.1 - 4.4e-13 49.2 0.0 1.1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM04590.1 - 2.3e-12 47.2 0.0 7e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM04590.1 - 5.8e-08 32.4 0.0 2.3e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM04590.1 - 1.7e-07 31.6 0.0 1.2e-06 28.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 CCM04590.1 - 4.2e-07 30.1 0.0 1.2e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 CCM04590.1 - 4.8e-06 27.1 0.0 1.8e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 CCM04590.1 - 0.00059 18.8 0.1 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 CCM04590.1 - 0.00089 18.8 2.1 0.006 16.2 1.5 2.5 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.21 CCM04590.1 - 0.0011 18.4 0.0 0.17 11.4 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PCMT PF01135.14 CCM04590.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 CCM04590.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF2974 PF11187.3 CCM04590.1 - 0.21 10.8 0.0 4 6.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Aldo_ket_red PF00248.16 CCM04591.1 - 2.2e-39 134.9 0.0 3.2e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3140 PF11338.3 CCM04592.1 - 0.2 11.8 0.2 0.57 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) Snf7 PF03357.16 CCM04593.1 - 4.2e-17 62.0 13.8 7e-17 61.3 9.6 1.3 1 0 0 1 1 1 1 Snf7 Baculo_PEP_C PF04513.7 CCM04593.1 - 0.35 10.6 2.8 0.22 11.3 0.6 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.1 CCM04593.1 - 1.1 9.2 7.9 0.073 13.0 1.2 2.3 2 0 0 2 2 2 0 FlxA-like protein Seryl_tRNA_N PF02403.17 CCM04593.1 - 1.9 8.5 14.9 0.15 12.0 1.5 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 CCM04593.1 - 3.2 8.0 7.1 6.9 6.9 0.7 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 CCM04593.1 - 3.5 6.4 8.1 0.2 10.5 1.6 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMEM51 PF15345.1 CCM04594.1 - 3.6e-05 23.5 0.2 3.6e-05 23.5 0.1 2.2 3 1 0 3 3 3 1 Transmembrane protein 51 gpUL132 PF11359.3 CCM04594.1 - 0.0021 17.4 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycoprotein UL132 TMEM154 PF15102.1 CCM04594.1 - 0.0059 16.3 0.1 0.0059 16.3 0.1 2.5 3 0 0 3 3 3 1 TMEM154 protein family Mid2 PF04478.7 CCM04594.1 - 0.024 14.0 0.3 0.052 12.9 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor CD34_antigen PF06365.7 CCM04594.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family SNF2_N PF00176.18 CCM04596.1 - 3.6e-66 222.9 0.0 5.1e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 CCM04596.1 - 1e-33 116.7 9.9 1.9e-33 115.8 6.9 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 CCM04596.1 - 2.3e-14 52.9 0.0 4.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCM04596.1 - 3.6e-09 35.8 0.0 1.4e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 CCM04596.1 - 0.0074 16.4 0.1 0.24 11.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain GYF PF02213.11 CCM04597.1 - 2.3e-05 23.8 0.1 5.3e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 GYF domain SPT16 PF08644.6 CCM04597.1 - 0.15 11.8 1.4 0.34 10.7 0.9 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4407 PF14362.1 CCM04597.1 - 0.98 8.3 7.5 1.6 7.6 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PQ-loop PF04193.9 CCM04598.1 - 1e-35 121.0 10.9 5e-18 64.3 0.0 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 CCM04598.1 - 0.024 14.5 0.9 0.059 13.2 0.6 1.7 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange CLTH PF10607.4 CCM04599.1 - 1.6e-13 50.5 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CCM04599.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 LisH Ribosomal_L30_N PF08079.7 CCM04601.1 - 3.5e-25 87.8 18.5 8e-25 86.6 12.8 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CCM04601.1 - 6.9e-20 70.3 1.2 1.6e-19 69.1 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e p450 PF00067.17 CCM04602.1 - 3.7e-74 249.9 0.0 4.2e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CotH PF08757.6 CCM04602.1 - 0.12 11.5 0.1 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 CotH protein DNA_methylase PF00145.12 CCM04603.1 - 4.3e-41 141.1 0.0 1.2e-40 139.6 0.0 1.7 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.3 CCM04603.1 - 6.7e-11 42.0 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.13 CCM04603.1 - 9.8e-07 28.5 0.0 0.0003 20.5 0.0 2.6 2 0 0 2 2 2 2 BAH domain Met_10 PF02475.11 CCM04603.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein TniQ PF06527.6 CCM04603.1 - 0.11 12.6 1.2 1 9.5 0.1 2.8 2 1 1 3 3 3 0 TniQ DUF2372 PF10178.4 CCM04605.1 - 0.0051 16.9 0.0 0.036 14.1 0.0 2.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) DUF2665 PF11654.3 CCM04606.1 - 9.1e-17 60.3 0.7 1e-16 60.2 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) NatB_MDM20 PF09797.4 CCM04607.1 - 5e-70 236.0 2.6 1e-69 235.0 1.8 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit RPA_C PF08784.6 CCM04607.1 - 1.1e-10 41.8 0.1 4.9e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Replication protein A C terminal TPR_14 PF13428.1 CCM04607.1 - 5.4e-07 29.6 0.4 0.22 12.2 0.0 5.5 3 1 3 6 6 6 1 Tetratricopeptide repeat tRNA_anti-codon PF01336.20 CCM04607.1 - 7.2e-07 28.9 0.1 1.5e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TPR_19 PF14559.1 CCM04607.1 - 2e-05 24.8 7.1 0.26 11.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 CCM04607.1 - 3.5e-05 24.1 0.0 3.5e-05 24.1 0.0 3.6 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_16 PF13432.1 CCM04607.1 - 0.0005 20.6 5.3 0.89 10.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat GRP PF07172.6 CCM04607.1 - 0.034 14.6 12.4 0.062 13.7 8.6 1.4 1 0 0 1 1 1 0 Glycine rich protein family TPR_11 PF13414.1 CCM04607.1 - 0.077 12.6 2.3 0.29 10.8 0.1 2.9 3 0 0 3 3 3 0 TPR repeat HTH_6 PF01418.12 CCM04607.1 - 0.083 12.6 0.0 0.29 10.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family FAD-oxidase_C PF02913.14 CCM04608.1 - 9.7e-56 188.8 0.0 1.4e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCM04608.1 - 4e-14 52.2 0.0 1e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain tRNA_anti-codon PF01336.20 CCM04609.1 - 0.004 16.9 0.1 0.0076 16.0 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 CCM04609.1 - 0.058 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal Lipase_GDSL PF00657.17 CCM04610.1 - 1.3e-09 38.2 0.0 1.6e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CCM04610.1 - 4.6e-08 33.4 0.0 9.3e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ribosomal_L24e PF01246.15 CCM04611.1 - 2.7e-30 104.0 3.9 7.3e-30 102.6 2.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 CCM04611.1 - 0.039 13.5 5.3 0.069 12.7 3.7 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif SH2_2 PF14633.1 CCM04612.1 - 5e-70 234.9 0.5 5e-70 234.9 0.3 2.0 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 CCM04612.1 - 8.1e-32 109.7 1.4 8.1e-32 109.7 1.0 3.3 5 0 0 5 5 5 1 Death-like domain of SPT6 HHH_7 PF14635.1 CCM04612.1 - 3.2e-29 101.0 0.0 7.2e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 CCM04612.1 - 4.4e-29 100.9 0.0 1.1e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 CCM04612.1 - 8.2e-21 73.9 29.9 8.2e-21 73.9 20.7 5.7 4 1 2 6 6 6 2 Acidic N-terminal SPT6 HTH_44 PF14641.1 CCM04612.1 - 2.3e-16 59.8 0.1 7.4e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 CCM04612.1 - 6e-08 32.3 0.0 5.4e-06 26.1 0.0 2.8 3 0 0 3 3 3 1 SH2 domain S1 PF00575.18 CCM04612.1 - 0.0026 17.8 0.2 0.0061 16.6 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.2 CCM04612.1 - 0.015 15.1 0.0 0.053 13.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif WD40 PF00400.27 CCM04614.1 - 2.1e-09 36.9 17.2 0.016 15.1 0.3 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat PEPCK_ATP PF01293.15 CCM04614.1 - 0.11 10.9 0.0 0.22 10.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase SRP54 PF00448.17 CCM04615.1 - 1.4e-74 249.8 0.9 2.1e-74 249.2 0.6 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 CCM04615.1 - 1.3e-15 57.2 2.9 2.6e-15 56.2 2.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 CCM04615.1 - 1.7e-06 27.9 0.1 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CCM04615.1 - 1.9e-06 27.4 0.2 3.6e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 CCM04615.1 - 0.00026 20.4 0.4 0.002 17.6 0.2 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 CCM04615.1 - 0.00035 20.3 0.1 0.00073 19.2 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CCM04615.1 - 0.0011 18.0 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 CCM04615.1 - 0.0026 16.5 0.2 0.0067 15.2 0.0 1.8 1 1 1 2 2 2 1 ArgK protein AAA_31 PF13614.1 CCM04615.1 - 0.013 15.4 0.0 6 6.7 0.0 2.5 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCM04615.1 - 0.02 15.7 0.0 0.055 14.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain 6PF2K PF01591.13 CCM04615.1 - 0.045 12.8 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2201 PF09967.4 CCM04615.1 - 0.046 13.7 0.4 0.29 11.1 0.0 2.2 2 1 1 3 3 3 0 VWA-like domain (DUF2201) AAA_22 PF13401.1 CCM04615.1 - 0.052 13.6 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CCM04615.1 - 0.055 13.0 0.8 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CCM04615.1 - 0.065 11.8 0.3 0.57 8.7 0.0 2.4 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SRP_SPB PF02978.14 CCM04616.1 - 2.4e-12 47.0 0.1 2.4e-12 47.0 0.1 3.5 3 0 0 3 3 3 1 Signal peptide binding domain Snf7 PF03357.16 CCM04616.1 - 0.12 11.7 6.9 0.21 10.9 4.8 1.4 1 0 0 1 1 1 0 Snf7 RRM_1 PF00076.17 CCM04617.1 - 6.7e-82 269.1 4.0 2.7e-20 71.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04617.1 - 4.2e-58 193.2 0.7 5.3e-16 58.3 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM04617.1 - 2.9e-43 145.5 0.3 1.1e-10 41.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CCM04617.1 - 3.2e-28 97.1 2.4 4.4e-28 96.7 0.8 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 CCM04617.1 - 0.0019 17.9 2.9 3.6 7.4 0.1 4.0 4 0 0 4 4 4 1 Limkain b1 OB_RNB PF08206.6 CCM04617.1 - 0.0092 15.4 1.6 11 5.5 0.0 3.4 3 0 0 3 3 3 1 Ribonuclease B OB domain DUF939_C PF11728.3 CCM04617.1 - 0.022 14.6 2.2 0.024 14.4 0.1 2.0 2 0 0 2 2 2 0 DUF939 C-terminal domain Nup35_RRM_2 PF14605.1 CCM04617.1 - 0.023 14.4 0.3 7.2 6.4 0.0 3.8 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 CCM04617.1 - 0.047 13.9 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis central region SCAMP PF04144.8 CCM04618.1 - 1.2e-41 142.5 2.5 1.4e-41 142.2 1.7 1.0 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.3 CCM04618.1 - 0.24 10.5 1.6 0.39 9.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CtnDOT_TraJ PF07863.6 CCM04618.1 - 1.2 9.7 7.3 0.23 11.9 1.5 2.2 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Isochorismatase PF00857.15 CCM04619.1 - 3.9e-18 65.9 0.0 7.7e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family ADK PF00406.17 CCM04620.1 - 1.3e-43 148.4 0.0 2.2e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCM04620.1 - 2.9e-12 46.0 0.0 7.1e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid NAD_binding_10 PF13460.1 CCM04620.1 - 1.4e-10 41.5 0.0 3.4e-09 36.9 0.0 2.9 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CCM04620.1 - 4.6e-06 26.2 0.1 3.4e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_17 PF13207.1 CCM04620.1 - 2.2e-05 25.2 0.0 4.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCM04620.1 - 2.8e-05 23.9 0.0 9.8e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCM04620.1 - 0.00015 22.1 0.0 0.00032 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain 3Beta_HSD PF01073.14 CCM04620.1 - 0.05 12.3 0.0 0.1 11.3 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AAA_24 PF13479.1 CCM04620.1 - 0.079 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Methyltransf_PK PF05891.7 CCM04621.1 - 2.8e-34 118.3 0.0 1.5e-32 112.6 0.0 2.5 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 CCM04621.1 - 0.00089 19.8 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM04621.1 - 0.0039 16.9 0.0 0.005 16.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CCM04621.1 - 0.0068 15.6 0.0 0.024 13.8 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_11 PF08241.7 CCM04621.1 - 0.083 13.3 0.0 3.3 8.2 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Swi3 PF07962.7 CCM04622.1 - 4.8e-27 93.4 0.1 7.3e-27 92.8 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 EzrA PF06160.7 CCM04624.1 - 0.12 10.5 18.1 0.18 9.9 12.6 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Filament PF00038.16 CCM04624.1 - 0.15 11.5 21.6 0.24 10.8 6.8 2.5 1 1 1 2 2 2 0 Intermediate filament protein Prominin PF05478.6 CCM04624.1 - 0.16 9.4 8.2 0.27 8.6 5.7 1.3 1 0 0 1 1 1 0 Prominin DUF262 PF03235.9 CCM04624.1 - 0.2 11.6 3.1 0.32 10.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 Spc7 PF08317.6 CCM04624.1 - 0.2 10.2 21.2 0.32 9.6 5.1 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CCM04624.1 - 0.39 9.8 4.0 1 8.4 2.1 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF342 PF03961.8 CCM04624.1 - 0.75 8.1 10.7 1 7.6 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 CCM04624.1 - 0.89 9.4 5.6 4.4 7.2 0.2 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 CCM04624.1 - 1.1 6.4 22.4 1.5 6.0 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EAP30 PF04157.11 CCM04624.1 - 1.4 8.0 13.2 2.2 7.3 8.3 1.9 2 0 0 2 2 2 0 EAP30/Vps36 family ACCA PF03255.9 CCM04624.1 - 1.6 8.2 14.0 4.4 6.8 4.5 3.8 1 1 3 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit UPF0242 PF06785.6 CCM04624.1 - 2 7.0 12.0 2.8 6.5 8.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Atg14 PF10186.4 CCM04624.1 - 2.3 7.0 19.4 4.2 6.2 13.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 CCM04624.1 - 2.7 5.7 11.3 4.7 4.9 7.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myb_DNA-bind_4 PF13837.1 CCM04624.1 - 3.5 7.8 12.7 3.3 7.9 6.0 2.9 3 1 1 4 4 3 0 Myb/SANT-like DNA-binding domain HAUS-augmin3 PF14932.1 CCM04624.1 - 7.1 5.7 21.9 23 4.0 15.2 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Cluap1 PF10234.4 CCM04624.1 - 7.6 5.6 17.5 21 4.1 11.9 1.9 1 1 0 1 1 1 0 Clusterin-associated protein-1 Peptidase_C6 PF00851.13 CCM04624.1 - 9.2 4.7 10.4 14 4.2 7.2 1.2 1 0 0 1 1 1 0 Helper component proteinase HSP70 PF00012.15 CCM04625.1 - 0.088 10.7 0.1 0.71 7.7 0.0 2.1 2 1 0 2 2 2 0 Hsp70 protein Epimerase PF01370.16 CCM04626.1 - 1.4e-15 57.3 0.0 2.2e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM04626.1 - 1.9e-07 31.3 1.5 4e-07 30.2 1.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCM04626.1 - 1.9e-05 24.0 1.6 3.1e-05 23.3 1.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 CCM04626.1 - 4.6e-05 22.4 0.2 0.0068 15.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 CCM04626.1 - 0.00032 19.4 0.0 0.00045 19.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCM04626.1 - 0.035 14.0 4.8 0.24 11.2 3.3 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Spore_YpjB PF09577.5 CCM04627.1 - 0.012 15.2 0.1 0.045 13.3 0.0 1.9 1 1 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) SlyX PF04102.7 CCM04627.1 - 0.098 13.0 6.1 0.077 13.3 1.9 2.5 2 1 1 3 3 3 0 SlyX Ten1_2 PF15490.1 CCM04627.1 - 0.13 11.8 2.6 0.31 10.6 1.8 1.7 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit HSP70 PF00012.15 CCM04628.1 - 0.15 9.9 0.1 0.26 9.1 0.0 1.3 2 0 0 2 2 2 0 Hsp70 protein RNase_T PF00929.19 CCM04629.1 - 7e-22 78.4 0.0 9.9e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CCM04629.1 - 0.00046 19.7 0.0 0.00094 18.7 0.0 1.4 1 1 0 1 1 1 1 3'-5' exonuclease Mito_carr PF00153.22 CCM04630.1 - 4.8e-56 186.4 2.8 3.3e-20 71.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 CCM04630.1 - 2.3 8.0 7.4 13 5.6 0.0 3.0 3 0 0 3 3 3 0 Colicin V production protein CENP-Q PF13094.1 CCM04633.1 - 1.2 9.1 13.7 1.1 9.2 1.8 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cornichon PF03311.9 CCM04634.1 - 1.8e-45 154.1 2.1 2e-45 154.0 1.4 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 CCM04634.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DUF3760 PF12586.3 CCM04635.1 - 0.017 14.9 0.1 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) RRM_1 PF00076.17 CCM04636.1 - 1.3e-08 34.3 0.0 2.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04636.1 - 6.7e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM04636.1 - 4.4e-05 23.2 0.0 7.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCM04636.1 - 0.0019 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif API5 PF05918.6 CCM04636.1 - 0.25 9.8 2.2 0.37 9.2 1.5 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Tetraspannin PF00335.15 CCM04637.1 - 5.5 6.2 9.5 5.5 6.1 4.1 2.5 1 1 1 2 2 2 0 Tetraspanin family Glyco_transf_49 PF13896.1 CCM04638.1 - 3.9e-33 114.9 0.0 1.2e-32 113.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Cupin_1 PF00190.17 CCM04638.1 - 5.3e-06 25.9 0.0 1.6e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Cupin Cupin_2 PF07883.6 CCM04638.1 - 1.7e-05 24.2 0.0 4.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 CCM04638.1 - 8.6e-05 22.2 0.2 0.00019 21.0 0.0 1.6 2 0 0 2 2 2 1 Cupin AraC_binding PF02311.14 CCM04638.1 - 0.00033 20.3 0.1 0.00069 19.3 0.1 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Methyltransf_11 PF08241.7 CCM04639.1 - 2.5e-07 31.0 0.0 4.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM04639.1 - 2.4e-06 27.3 0.0 3.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM04639.1 - 1.8e-05 24.4 0.0 8.2e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM04639.1 - 2.8e-05 23.3 0.0 4.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CCM04639.1 - 0.00082 19.7 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM04639.1 - 0.012 15.6 0.0 0.041 13.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCM04639.1 - 0.03 14.8 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 CCM04639.1 - 0.046 13.2 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CCM04639.1 - 0.055 14.0 0.0 0.2 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 CCM04639.1 - 0.11 11.9 0.0 0.45 9.9 0.0 1.8 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit adh_short PF00106.20 CCM04640.1 - 4e-10 39.8 0.0 7.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM04640.1 - 1.1e-07 31.8 0.0 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM04640.1 - 5.8e-06 26.4 0.0 8.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_2 PF00891.13 CCM04641.1 - 1.1e-27 96.7 0.0 1.6e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 CCM04641.1 - 0.0001 22.8 0.0 0.00022 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM04641.1 - 0.0011 18.7 0.0 0.004 16.8 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM04641.1 - 0.0026 17.3 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCM04641.1 - 0.041 13.2 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.11 CCM04642.1 - 1.7e-28 99.3 30.8 8.1e-27 93.8 11.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1156 PF06634.7 CCM04642.1 - 0.081 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) 2-Hacid_dh_C PF02826.14 CCM04643.1 - 1.2e-49 167.8 0.0 1.7e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCM04643.1 - 1.4e-18 66.6 0.0 1.6e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCM04643.1 - 2.7e-07 30.5 0.0 4.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CCM04643.1 - 0.00075 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 CCM04644.1 - 1.2e-50 171.0 0.0 1.7e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCM04644.1 - 2.2e-17 62.7 0.0 2.7e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCM04644.1 - 1.6e-05 24.8 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CCM04644.1 - 0.0051 16.1 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Pyr_redox PF00070.22 CCM04644.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2367 PF10164.4 CCM04645.1 - 0.018 14.8 0.1 0.018 14.8 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) DUF3530 PF12048.3 CCM04645.1 - 0.037 13.0 0.8 0.04 12.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PAT1 PF09770.4 CCM04645.1 - 4.6 5.3 11.2 5 5.2 7.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CCM04645.1 - 4.9 6.4 15.2 5.3 6.3 10.6 1.0 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 CCM04646.1 - 7.9e-38 130.0 23.5 7.9e-38 130.0 16.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM04646.1 - 6.9e-13 47.9 13.7 9.5e-13 47.5 9.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1156 PF06634.7 CCM04646.1 - 0.098 12.4 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) 2-Hacid_dh_C PF02826.14 CCM04647.1 - 4.2e-51 172.6 0.0 6.1e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCM04647.1 - 1.1e-16 60.5 0.0 1.3e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCM04647.1 - 2.5e-05 24.1 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CCM04647.1 - 0.089 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain RE_MjaI PF09568.5 CCM04647.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 MjaI restriction endonuclease DUF2263 PF10021.4 CCM04648.1 - 8.6e-20 71.2 0.0 1.9e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF218 PF02698.12 CCM04648.1 - 0.0068 15.9 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 1 DUF218 domain Peptidase_M20 PF01546.23 CCM04649.1 - 6.8e-21 74.6 0.0 1.1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCM04649.1 - 2.3e-08 33.7 0.1 5.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain 2-Hacid_dh_C PF02826.14 CCM04652.1 - 9.9e-52 174.6 0.0 1.4e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCM04652.1 - 3.9e-14 52.2 0.0 5.3e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCM04652.1 - 0.00044 20.1 0.0 0.00069 19.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CCM04652.1 - 0.0022 17.4 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 CCM04652.1 - 0.055 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RE_MjaI PF09568.5 CCM04652.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 MjaI restriction endonuclease MFS_1 PF07690.11 CCM04654.1 - 3.7e-14 52.2 54.3 3.9e-11 42.2 22.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CCM04654.1 - 0.0085 15.8 0.8 0.0085 15.8 0.6 2.3 2 0 0 2 2 2 1 MFS_1 like family DUF3810 PF12725.2 CCM04654.1 - 0.037 12.9 1.0 0.063 12.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) p450 PF00067.17 CCM04655.1 - 1.5e-73 247.9 0.0 2.9e-73 246.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 CCM04656.1 - 1e-48 166.0 0.0 4.9e-48 163.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CCM04656.1 - 2e-44 152.2 0.0 3.6e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 CCM04656.1 - 1e-32 113.0 0.0 1.7e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.1 CCM04656.1 - 3.6e-32 111.6 0.0 9.4e-32 110.3 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 CCM04656.1 - 3.3e-30 105.0 1.0 3.1e-26 92.1 0.2 2.8 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 CCM04656.1 - 1.9e-26 92.9 0.8 7.2e-23 81.3 0.2 2.8 2 0 0 2 2 2 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 CCM04656.1 - 1.5e-25 89.3 0.0 3e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 CCM04656.1 - 1.8e-08 34.1 0.0 4.5e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CCM04656.1 - 4e-07 30.1 0.1 1.2e-06 28.7 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 CCM04656.1 - 0.015 14.2 0.1 0.04 12.9 0.0 1.6 2 0 0 2 2 2 0 Thiolase, N-terminal domain ACP_syn_III PF08545.5 CCM04656.1 - 0.019 14.6 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.10 CCM04656.1 - 0.025 13.4 0.1 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 CCM04656.1 - 0.15 12.4 0.0 0.57 10.5 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Gelsolin PF00626.17 CCM04656.1 - 0.21 11.3 0.0 0.49 10.1 0.0 1.5 1 0 0 1 1 1 0 Gelsolin repeat NmrA PF05368.8 CCM04656.1 - 0.48 9.6 0.0 0.91 8.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family PTCB-BRCT PF12738.2 CCM04659.1 - 2.6e-12 46.4 0.0 4.2e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.21 CCM04659.1 - 2.2e-08 34.1 0.0 2.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 CCM04660.1 - 1.5e-12 47.2 0.2 3e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 WGR domain DUF3561 PF12084.3 CCM04663.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3561) PTCB-BRCT PF12738.2 CCM04664.1 - 9.5e-28 95.8 0.0 2.8e-14 52.6 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 CCM04664.1 - 1.4e-25 89.2 0.0 7.1e-09 35.6 0.0 4.6 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain DUF4139 PF13598.1 CCM04665.1 - 8.8e-55 186.2 1.1 7.2e-35 120.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 CCM04665.1 - 3e-10 40.4 3.4 2.9e-09 37.3 0.0 3.2 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 CCM04665.1 - 1.2 9.4 21.2 16 5.7 14.7 2.2 1 1 0 1 1 1 0 Nucleoporin FG repeat region DUF3748 PF12566.3 CCM04666.1 - 0.12 12.2 0.0 17 5.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3748) NAD_binding_10 PF13460.1 CCM04668.1 - 2.8e-17 63.3 0.3 5.2e-17 62.4 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM04668.1 - 1.7e-10 40.7 0.0 7.3e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CCM04668.1 - 0.00016 20.9 0.1 0.00022 20.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 CCM04668.1 - 0.00017 20.5 0.0 0.17 10.7 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain UDPG_MGDP_dh_N PF03721.9 CCM04668.1 - 0.00027 20.3 0.0 0.00044 19.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 CCM04668.1 - 0.0011 18.9 0.1 0.003 17.4 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 CCM04668.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 CCM04668.1 - 0.0032 16.2 0.0 0.99 8.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 CCM04668.1 - 0.0037 16.9 0.5 0.0066 16.1 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 CCM04668.1 - 0.0057 16.6 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.22 CCM04668.1 - 0.016 15.5 0.2 0.031 14.6 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Eno-Rase_NADH_b PF12242.3 CCM04668.1 - 0.019 14.7 0.3 0.055 13.2 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DapB_N PF01113.15 CCM04668.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fibrillarin PF01269.12 CCM04668.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin NAD_binding_4 PF07993.7 CCM04668.1 - 0.12 11.2 0.0 4.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Ldh_1_N PF00056.18 CCM04668.1 - 0.15 11.8 0.0 0.95 9.2 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.11 CCM04669.1 - 3.1e-24 85.3 16.3 2.3e-16 59.4 7.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Med7 PF05983.6 CCM04670.1 - 0.11 12.2 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 MED7 protein DUF1664 PF07889.7 CCM04671.1 - 0.095 12.4 0.7 1.5 8.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) AAA PF00004.24 CCM04672.1 - 2.8e-93 309.0 0.0 6.3e-47 159.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCM04672.1 - 1.4e-15 56.9 0.0 1.9e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCM04672.1 - 1.9e-12 47.4 0.2 0.0032 17.6 0.0 4.9 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 CCM04672.1 - 3.3e-12 47.2 0.0 1.4e-06 29.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCM04672.1 - 4.3e-12 46.4 6.3 0.00025 21.0 0.1 5.1 4 2 0 4 4 4 2 AAA ATPase domain AAA_33 PF13671.1 CCM04672.1 - 1e-10 41.6 0.0 5.4e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCM04672.1 - 1.2e-10 41.2 0.4 0.00071 19.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCM04672.1 - 7.1e-10 39.0 0.0 0.00093 19.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CCM04672.1 - 9.1e-10 38.5 0.0 0.0008 19.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CCM04672.1 - 4.3e-09 35.5 0.0 5.6e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 CCM04672.1 - 1.3e-08 34.2 0.0 0.0026 16.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CCM04672.1 - 3.9e-08 32.9 0.0 0.0082 15.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 CCM04672.1 - 5.4e-08 32.9 0.0 0.018 15.2 0.0 2.8 2 1 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 CCM04672.1 - 2.6e-07 30.2 3.3 0.42 9.9 0.0 4.3 2 2 1 4 4 4 2 AAA domain AAA_19 PF13245.1 CCM04672.1 - 3.2e-07 29.9 7.7 0.0027 17.4 0.1 4.7 5 1 0 5 5 3 2 Part of AAA domain Mg_chelatase PF01078.16 CCM04672.1 - 4.1e-07 29.3 0.2 0.028 13.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCM04672.1 - 4.7e-07 29.9 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CCM04672.1 - 6.7e-07 29.1 0.4 0.083 12.5 0.0 3.8 3 1 1 4 4 4 2 NACHT domain AAA_3 PF07726.6 CCM04672.1 - 2.9e-06 26.9 0.0 0.0075 15.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CCM04672.1 - 5e-06 26.8 0.0 0.088 13.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_18 PF13238.1 CCM04672.1 - 8.3e-06 26.1 0.0 0.074 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 CCM04672.1 - 2.4e-05 23.5 0.1 0.61 9.1 0.0 3.2 2 1 1 3 3 3 2 KaiC Sigma54_activ_2 PF14532.1 CCM04672.1 - 5.1e-05 23.3 0.0 0.44 10.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 CCM04672.1 - 5.2e-05 22.7 0.0 0.39 10.1 0.0 3.4 2 1 0 2 2 2 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 CCM04672.1 - 0.00012 22.0 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 CCM04672.1 - 0.00018 21.4 0.0 0.78 9.5 0.0 2.8 3 0 0 3 3 2 2 Shikimate kinase NB-ARC PF00931.17 CCM04672.1 - 0.00023 20.1 0.0 0.36 9.6 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.8 CCM04672.1 - 0.00025 20.0 0.0 0.011 14.6 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 CCM04672.1 - 0.00038 20.0 0.0 0.55 9.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 CCM04672.1 - 0.0005 19.8 0.0 1.9 8.1 0.0 3.1 2 2 1 3 3 3 1 Archaeal ATPase PhoH PF02562.11 CCM04672.1 - 0.00083 18.6 0.3 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Rad17 PF03215.10 CCM04672.1 - 0.0012 17.6 0.0 0.32 9.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 CCM04672.1 - 0.0012 17.7 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 CCM04672.1 - 0.0014 18.2 0.0 0.79 9.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Vps4_C PF09336.5 CCM04672.1 - 0.0023 17.7 0.1 0.5 10.2 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ATP-synt_ab PF00006.20 CCM04672.1 - 0.0033 16.9 0.0 0.78 9.1 0.0 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 CCM04672.1 - 0.012 15.2 0.0 2.1 8.0 0.0 2.8 2 1 0 3 3 2 0 NTPase AAA_11 PF13086.1 CCM04672.1 - 0.014 15.0 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCM04672.1 - 0.016 14.8 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CCM04672.1 - 0.018 14.0 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.13 CCM04672.1 - 0.026 14.1 0.0 3.6 7.1 0.0 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein CPT PF07931.7 CCM04672.1 - 0.048 13.2 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AFG1_ATPase PF03969.11 CCM04672.1 - 0.059 12.1 0.0 2.9 6.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase PduV-EutP PF10662.4 CCM04672.1 - 0.062 12.7 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CCM04672.1 - 0.064 12.6 0.1 15 4.9 0.0 3.2 3 1 0 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.18 CCM04672.1 - 0.07 13.0 0.0 13 5.7 0.0 3.2 2 1 1 3 3 3 0 50S ribosome-binding GTPase T2SE PF00437.15 CCM04672.1 - 0.075 11.9 0.0 4.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.10 CCM04672.1 - 0.081 12.7 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IPT PF01745.11 CCM04672.1 - 0.21 10.7 0.0 16 4.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase SRPRB PF09439.5 CCM04672.1 - 0.21 10.7 0.0 21 4.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CCM04672.1 - 0.27 10.4 0.2 7.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Abhydrolase_6 PF12697.2 CCM04673.1 - 1.6e-23 83.7 1.2 2e-23 83.4 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM04673.1 - 2e-09 37.3 0.0 5.6e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM04673.1 - 8.8e-07 28.7 0.0 2.3e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCM04673.1 - 1.1e-06 28.4 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CCM04673.1 - 0.00036 20.8 0.0 0.00049 20.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2305 PF10230.4 CCM04673.1 - 0.0025 17.2 0.0 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) NAD_binding_10 PF13460.1 CCM04674.1 - 2e-16 60.5 0.1 2.9e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM04674.1 - 2.1e-11 43.7 0.0 3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CCM04674.1 - 4.1e-06 26.0 0.2 5.2e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 CCM04674.1 - 0.00023 20.5 0.1 0.0003 20.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CCM04674.1 - 0.00024 21.0 0.3 0.00047 20.1 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 CCM04674.1 - 0.0055 16.5 0.1 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 CCM04674.1 - 0.0081 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CCM04674.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Fibrillarin PF01269.12 CCM04674.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin RmlD_sub_bind PF04321.12 CCM04674.1 - 0.033 13.0 0.1 0.17 10.7 0.0 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.12 CCM04674.1 - 0.079 13.3 0.6 0.16 12.4 0.4 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 CCM04674.1 - 0.096 11.3 0.0 4.1 6.0 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Rossmann-like PF10727.4 CCM04674.1 - 0.097 12.3 0.3 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Rossmann-like domain p450 PF00067.17 CCM04675.1 - 2.4e-70 237.3 0.0 1.8e-69 234.4 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 APH PF01636.18 CCM04676.1 - 2.8e-10 40.3 0.0 1.3e-09 38.1 0.0 2.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Rifin_STEVOR PF02009.11 CCM04677.1 - 0.0014 18.3 0.3 0.0041 16.8 0.0 1.8 2 0 0 2 2 2 1 Rifin/stevor family Rubrerythrin PF02915.12 CCM04677.1 - 0.0037 17.5 0.8 0.0068 16.7 0.6 1.3 1 0 0 1 1 1 1 Rubrerythrin TMEM154 PF15102.1 CCM04677.1 - 0.0058 16.3 0.1 0.0058 16.3 0.1 2.3 2 0 0 2 2 2 1 TMEM154 protein family Mid2 PF04478.7 CCM04677.1 - 0.045 13.1 1.2 0.13 11.7 0.9 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor p450 PF00067.17 CCM04678.1 - 1.1e-67 228.5 0.0 1.4e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YchF-GTPase_C PF06071.8 CCM04679.1 - 8.8e-36 121.5 0.1 2.1e-35 120.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CCM04679.1 - 6.8e-12 45.3 0.0 3.9e-11 42.9 0.0 2.0 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCM04679.1 - 0.0094 15.2 0.2 0.019 14.2 0.2 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RPAP1_N PF08621.5 CCM04679.1 - 0.025 14.1 1.7 0.047 13.2 1.2 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal IIGP PF05049.8 CCM04679.1 - 0.072 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) BetaGal_dom3 PF13363.1 CCM04679.1 - 0.087 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Pex14_N PF04695.8 CCM04680.1 - 0.21 11.6 4.2 0.3 11.1 2.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAP PF07174.6 CCM04680.1 - 0.38 10.0 11.9 0.47 9.6 8.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF3295 PF11702.3 CCM04680.1 - 0.56 9.1 3.8 0.61 9.0 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Sporozoite_P67 PF05642.6 CCM04680.1 - 9.7 3.9 17.6 11 3.6 12.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA_13 PF13166.1 CCM04682.1 - 0.071 11.5 2.4 0.11 10.9 1.6 1.2 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 CCM04682.1 - 0.093 11.1 0.7 0.14 10.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CALCOCO1 PF07888.6 CCM04682.1 - 0.36 9.0 6.6 0.73 8.0 4.6 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fmp27_WPPW PF10359.4 CCM04682.1 - 3 6.1 4.5 4.8 5.4 3.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PITH PF06201.8 CCM04683.1 - 3.5e-39 133.9 0.0 4.3e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain UBX PF00789.15 CCM04684.1 - 3.3e-07 30.2 1.5 1e-06 28.7 1.0 1.8 1 1 0 1 1 1 1 UBX domain Pro_isomerase PF00160.16 CCM04685.1 - 3e-43 147.6 0.0 6.8e-43 146.5 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 CCM04686.1 - 1e-48 165.0 0.0 3.2e-47 160.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ras PF00071.17 CCM04686.1 - 5.3e-40 136.4 0.0 2e-39 134.5 0.0 1.8 2 0 0 2 2 2 1 Ras family Helicase_C PF00271.26 CCM04686.1 - 3.2e-28 97.3 0.0 6.8e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Miro PF08477.8 CCM04686.1 - 1.3e-15 57.9 0.0 1.7e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CCM04686.1 - 8.7e-07 28.5 0.0 2.8e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ResIII PF04851.10 CCM04686.1 - 1.2e-05 25.2 0.0 3.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CCM04686.1 - 0.011 14.1 0.0 0.083 11.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 CCM04686.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF2443 PF10398.4 CCM04686.1 - 0.032 14.0 0.2 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) MMR_HSR1 PF01926.18 CCM04686.1 - 0.068 13.1 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase GRP PF07172.6 CCM04686.1 - 0.64 10.5 69.8 3.9 8.0 20.3 2.6 2 0 0 2 2 2 0 Glycine rich protein family Abhydrolase_5 PF12695.2 CCM04687.1 - 3.3e-12 46.3 0.0 5.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM04687.1 - 3.9e-08 33.4 0.7 7.5e-08 32.5 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCM04687.1 - 0.001 18.3 0.0 0.0049 16.1 0.0 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 CCM04687.1 - 0.0036 16.7 0.0 0.0068 15.8 0.0 1.6 1 1 0 1 1 1 1 Putative esterase PhoPQ_related PF10142.4 CCM04687.1 - 0.0038 15.7 0.0 0.0089 14.5 0.0 1.6 1 1 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Alba PF01918.16 CCM04689.1 - 0.023 14.2 0.0 0.25 10.9 0.0 2.5 1 1 0 1 1 1 0 Alba PHD PF00628.24 CCM04690.1 - 8.9e-09 34.9 7.2 1.7e-08 34.0 5.0 1.5 1 0 0 1 1 1 1 PHD-finger APC10 PF03256.11 CCM04691.1 - 1.6e-46 158.3 0.0 1.9e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 CCM04691.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.6 1 1 0 1 1 1 0 F5/8 type C domain ThiF PF00899.16 CCM04692.1 - 3.9e-46 156.2 0.2 6.2e-46 155.5 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CCM04692.1 - 1e-27 95.5 0.4 3.2e-27 93.9 0.1 2.1 3 0 0 3 3 3 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 CCM04692.1 - 7.4e-05 22.8 0.5 0.0011 19.0 0.4 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CCM04692.1 - 0.11 12.7 0.1 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding zf-Tim10_DDP PF02953.10 CCM04693.1 - 2.4e-21 74.7 2.4 2.9e-21 74.5 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.6 CCM04693.1 - 0.012 15.4 0.9 0.015 15.0 0.7 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Paramyxo_PNT PF13825.1 CCM04693.1 - 0.11 11.7 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus DnaJ PF00226.26 CCM04694.1 - 1.6e-24 85.3 0.7 4.3e-24 84.0 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 CCM04694.1 - 1.2e-11 44.4 2.3 1.1e-08 34.9 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM04694.1 - 1.4e-10 40.9 4.6 1.6e-07 31.2 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCM04694.1 - 1.3e-07 31.6 0.6 0.013 15.6 0.0 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CCM04694.1 - 1.9e-05 24.6 3.5 0.04 14.2 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM04694.1 - 5.8e-05 23.1 2.1 0.28 11.6 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCM04694.1 - 0.00021 21.0 1.5 0.091 12.6 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger Metaviral_G PF09595.5 CCM04694.1 - 7.7 6.1 14.0 0.39 10.3 5.0 2.2 3 0 0 3 3 3 0 Metaviral_G glycoprotein Prp18 PF02840.10 CCM04695.1 - 1e-52 177.8 0.0 1e-52 177.8 0.0 3.0 4 0 0 4 4 4 1 Prp18 domain PRP4 PF08799.6 CCM04695.1 - 6.7e-11 41.2 5.6 2.1e-10 39.6 3.9 2.0 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Atrophin-1 PF03154.10 CCM04695.1 - 5.7 4.9 9.9 4 5.4 5.5 1.6 2 0 0 2 2 2 0 Atrophin-1 family COX6B PF02297.12 CCM04696.1 - 2.4e-18 65.9 7.5 3e-18 65.6 5.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 CCM04696.1 - 0.029 14.2 1.8 0.083 12.8 1.1 1.9 1 1 1 2 2 2 0 CHCH domain RRM_1 PF00076.17 CCM04697.1 - 9.4e-14 50.8 0.2 1.5e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04697.1 - 2e-12 46.9 0.0 3.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM04697.1 - 0.0083 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) P34-Arc PF04045.9 CCM04698.1 - 2.5e-102 341.3 0.0 2.9e-102 341.0 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Homeobox PF00046.24 CCM04699.1 - 9.5e-19 66.7 4.1 3.2e-18 65.0 2.8 1.9 2 0 0 2 2 2 1 Homeobox domain RRM_1 PF00076.17 CCM04700.1 - 4.8e-18 64.5 0.0 8.5e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04700.1 - 2.5e-17 62.5 0.0 4e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 CCM04700.1 - 1e-16 60.9 0.2 1.6e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 CCM04700.1 - 2.3e-08 33.7 0.0 4.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UbiA PF01040.13 CCM04701.1 - 1.4e-28 99.8 19.2 1.9e-28 99.3 13.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Mcp5_PH PF12814.2 CCM04701.1 - 0.0093 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology AKAP2_C PF15304.1 CCM04702.1 - 0.0012 18.5 2.3 0.0012 18.5 1.6 2.0 2 0 0 2 2 2 1 A-kinase anchor protein 2 C-terminus zf-C2H2_jaz PF12171.3 CCM04702.1 - 0.036 14.2 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCM04702.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Citrate_synt PF00285.16 CCM04703.1 - 1.5e-97 326.5 0.0 1.7e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 CCM04703.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Methyltransf_4 PF02390.12 CCM04704.1 - 4.8e-55 185.6 0.0 6.3e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCM04704.1 - 2.2e-05 24.9 0.0 4.1e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM04704.1 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM04704.1 - 0.0027 18.0 0.0 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM04704.1 - 0.011 16.1 0.0 0.12 12.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCM04704.1 - 0.032 14.6 0.0 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 CCM04704.1 - 0.04 13.2 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 CCM04704.1 - 0.18 11.3 0.0 0.38 10.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain RNase_PH PF01138.16 CCM04705.1 - 4.7e-37 127.2 0.1 9.6e-37 126.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCM04705.1 - 0.00028 20.7 0.0 0.00058 19.7 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NAPRTase PF04095.11 CCM04706.1 - 1.4e-54 184.9 0.0 2.1e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Suppressor_P21 PF11479.3 CCM04706.1 - 0.089 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 RNA silencing suppressor P21 Terpene_synth_C PF03936.11 CCM04708.1 - 4.8e-21 75.2 0.0 6.9e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain WD40 PF00400.27 CCM04709.1 - 8.1e-45 149.1 19.8 5.8e-09 35.4 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 CCM04709.1 - 6.2e-13 48.2 2.3 6.2e-13 48.2 1.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM04709.1 - 1.6e-10 40.3 6.9 2.1e-09 36.7 1.6 2.8 3 0 0 3 3 3 2 F-box domain Nup160 PF11715.3 CCM04709.1 - 6.8e-06 24.4 4.5 0.18 9.8 0.2 3.7 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 CCM04709.1 - 0.01 14.9 0.4 0.35 9.9 0.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 CCM04709.1 - 0.044 13.2 0.3 3.8 6.8 0.0 2.5 1 1 0 2 2 2 0 PQQ-like domain Aminotran_5 PF00266.14 CCM04710.1 - 1.1e-81 274.4 0.3 1.5e-66 224.6 0.1 2.1 1 1 1 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCM04710.1 - 1.9e-08 33.8 0.8 3.5e-08 32.9 0.6 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCM04710.1 - 2.3e-05 23.6 0.2 0.00011 21.3 0.2 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CCM04710.1 - 0.0092 14.3 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 CCM04710.1 - 0.072 12.9 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain Peripla_BP_4 PF13407.1 CCM04710.1 - 0.12 11.7 0.1 0.47 9.7 0.0 1.9 2 1 1 3 3 3 0 Periplasmic binding protein domain RRM_1 PF00076.17 CCM04711.1 - 4.3e-30 103.1 0.0 9.2e-17 60.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04711.1 - 1.9e-23 82.2 0.0 4.5e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM04711.1 - 8.8e-14 51.1 0.0 2.7e-07 30.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCM04711.1 - 3.6e-05 23.5 0.0 0.00047 19.9 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCM04711.1 - 0.00014 21.5 0.0 0.005 16.5 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CCM04711.1 - 0.00018 21.1 0.2 0.044 13.5 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 HET PF06985.6 CCM04712.1 - 4e-18 65.9 1.8 1.9e-14 53.9 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3429 PF11911.3 CCM04713.1 - 1.4e-35 122.3 14.8 2.1e-35 121.7 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) MerC PF03203.9 CCM04713.1 - 1.1 9.6 4.6 1.1 9.5 2.2 1.7 1 1 1 2 2 2 0 MerC mercury resistance protein CAP_GLY PF01302.20 CCM04714.1 - 2e-19 69.0 0.4 3.4e-19 68.3 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 CCM04714.1 - 2.2e-14 52.9 3.4 3.7e-07 29.8 0.3 5.1 1 1 6 7 7 7 5 Leucine rich repeat LRR_4 PF12799.2 CCM04714.1 - 6.2e-13 48.0 8.5 2.9e-06 26.7 0.1 5.8 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CCM04714.1 - 0.0002 20.9 0.0 0.003 17.1 0.0 2.2 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.28 CCM04714.1 - 0.00073 19.2 13.9 0.14 12.2 0.1 6.9 5 2 1 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 CCM04714.1 - 0.071 13.2 10.2 2.2 8.5 0.1 5.8 7 0 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 CCM04714.1 - 0.085 13.1 9.7 14 6.4 0.0 6.8 8 1 0 8 8 8 0 Leucine rich repeat ECH_C PF13766.1 CCM04715.1 - 5.9e-30 103.8 0.1 1.5e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CCM04715.1 - 5.7e-23 81.2 0.0 5.5e-22 78.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2497 PF10691.4 CCM04715.1 - 0.031 14.2 0.2 3.9 7.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2497) Skp1 PF01466.14 CCM04716.1 - 1.5e-39 133.8 1.2 2.4e-39 133.2 0.9 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CCM04716.1 - 1.2e-24 86.1 0.4 3.1e-24 84.8 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CCM04716.1 - 0.00052 19.9 0.0 0.022 14.7 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF4375 PF14300.1 CCM04716.1 - 0.066 13.1 0.7 0.33 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Ribosomal_L27 PF01016.14 CCM04717.1 - 3.8e-32 109.9 0.3 5e-32 109.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein F-box-like PF12937.2 CCM04718.1 - 1.3e-09 37.6 2.1 5.1e-09 35.7 1.4 2.1 1 0 0 1 1 1 1 F-box-like DUF3074 PF11274.3 CCM04719.1 - 1.8e-33 115.6 0.0 2.6e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Gln-synt_C PF00120.19 CCM04720.1 - 6.8e-54 182.7 0.0 1.7e-52 178.1 0.0 2.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Skp1 PF01466.14 CCM04720.1 - 2e-19 69.4 0.0 3.4e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CCM04720.1 - 0.043 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain WD40 PF00400.27 CCM04721.1 - 0.0037 17.0 4.2 0.28 11.1 0.0 4.9 5 1 0 5 5 5 1 WD domain, G-beta repeat Reg_prop PF07494.6 CCM04721.1 - 0.05 13.6 0.2 24 5.4 0.0 3.7 3 0 0 3 3 3 0 Two component regulator propeller Utp21 PF04192.7 CCM04722.1 - 1.6e-57 194.3 1.5 2.9e-57 193.5 1.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CCM04722.1 - 4.2e-19 67.6 12.2 3.9e-06 26.5 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCM04722.1 - 0.015 13.4 1.5 0.56 8.2 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 SRPRB PF09439.5 CCM04723.1 - 7e-23 80.7 0.0 9.3e-23 80.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CCM04723.1 - 3.5e-17 62.1 0.0 5.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCM04723.1 - 2.7e-10 39.8 0.0 3.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCM04723.1 - 1.2e-07 32.2 0.0 1.7e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCM04723.1 - 1.3e-07 31.5 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCM04723.1 - 2.2e-05 23.9 0.3 0.019 14.3 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.17 CCM04723.1 - 0.00071 18.9 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CCM04723.1 - 0.0023 16.7 0.7 0.16 10.6 0.0 2.3 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.1 CCM04723.1 - 0.01 15.3 0.1 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 CCM04723.1 - 0.022 14.0 0.1 0.054 12.7 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.1 CCM04723.1 - 0.041 13.8 0.5 0.095 12.6 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CCM04723.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CCM04723.1 - 0.11 12.2 0.1 5.4 6.8 0.0 2.2 1 1 1 2 2 2 0 Dynamin family ABC_tran PF00005.22 CCM04723.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mannosyl_trans PF05007.8 CCM04724.1 - 9.9e-76 254.7 20.0 1.3e-75 254.3 13.9 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) Arf PF00025.16 CCM04724.1 - 8e-63 210.8 0.0 1.2e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PIG-U PF06728.8 CCM04724.1 - 3.7e-11 42.5 5.3 3.7e-11 42.5 3.7 1.9 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U SRPRB PF09439.5 CCM04724.1 - 7.7e-10 38.2 0.0 1.2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCM04724.1 - 2.2e-08 33.1 0.1 1.2e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CCM04724.1 - 8e-06 25.7 0.0 1.8e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CCM04724.1 - 1e-05 26.0 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CCM04724.1 - 6.6e-05 22.3 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CCM04724.1 - 0.0013 17.8 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CCM04724.1 - 0.12 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Cofilin_ADF PF00241.15 CCM04725.1 - 2.4e-10 40.3 0.0 2.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MFS_1 PF07690.11 CCM04726.1 - 1.7e-21 76.3 31.4 6e-17 61.3 13.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM04726.1 - 6.5e-06 24.9 7.2 6.5e-06 24.9 5.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM04727.1 - 1.6e-23 83.0 31.9 1.3e-15 57.0 16.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Exo_endo_phos PF03372.18 CCM04728.1 - 7.7e-16 58.7 0.1 9.8e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L3 PF00297.17 CCM04729.1 - 5.1e-41 140.8 1.3 1e-39 136.5 0.9 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 PCYCGC PF13798.1 CCM04729.1 - 0.41 10.3 1.8 4.3 7.0 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function with PCYCGC motif Rrn6 PF10214.4 CCM04730.1 - 1.2e-11 43.4 5.2 9e-07 27.3 0.1 2.9 2 1 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Mito_carr PF00153.22 CCM04731.1 - 8.3e-40 134.4 1.2 9.6e-15 54.0 0.0 4.0 4 1 0 4 4 4 3 Mitochondrial carrier protein MOR2-PAG1_N PF14222.1 CCM04734.1 - 6.6e-144 480.6 0.0 1.1e-142 476.6 0.0 2.2 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 CCM04734.1 - 6.4e-80 268.6 1.1 2.2e-79 266.9 0.5 2.2 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 CCM04734.1 - 4.9e-19 67.5 0.1 1.4e-11 42.8 0.0 3.1 3 0 0 3 3 3 3 Cell morphogenesis central region Nucleoplasmin PF03066.10 CCM04735.1 - 0.064 12.7 0.4 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 CCM04735.1 - 0.18 12.1 2.1 0.49 10.7 1.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_mis_repair PF01119.14 CCM04736.1 - 1.1e-28 99.0 0.0 1.9e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCM04736.1 - 2.1e-13 50.0 0.0 5e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCM04736.1 - 1.8e-11 43.7 0.0 3.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BRF1 PF07741.8 CCM04736.1 - 0.098 12.8 1.8 0.23 11.7 1.2 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PC_rep PF01851.17 CCM04738.1 - 1.5e-23 81.6 14.4 2.1e-05 24.4 0.1 8.4 7 0 0 7 7 7 7 Proteasome/cyclosome repeat DSPc PF00782.15 CCM04740.1 - 9.6e-05 21.9 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCM04740.1 - 0.011 15.9 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCM04740.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Acetyltransf_9 PF13527.1 CCM04741.1 - 0.0021 17.8 0.0 0.0058 16.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCM04741.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF917 PF06032.7 CCM04742.1 - 3e-109 364.7 0.0 4.2e-109 364.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 CCM04742.1 - 1.6e-16 60.3 6.0 1.6e-16 60.2 1.7 2.5 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Amidase PF01425.16 CCM04743.1 - 9.7e-75 252.0 0.0 1.1e-74 251.8 0.0 1.0 1 0 0 1 1 1 1 Amidase BTV_NS2 PF04514.7 CCM04744.1 - 0.0037 16.2 0.8 0.0046 15.8 0.5 1.1 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 Fic PF02661.13 CCM04745.1 - 3.4e-07 30.8 0.0 8.4e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Fic/DOC family adh_short PF00106.20 CCM04748.1 - 1.4e-29 103.1 3.0 2e-29 102.6 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04748.1 - 4e-15 55.9 1.7 4e-15 55.9 1.2 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CCM04748.1 - 2.1e-07 30.6 0.1 4e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CCM04748.1 - 0.00014 20.9 0.1 0.00023 20.1 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CCM04748.1 - 0.00014 21.5 0.7 0.00037 20.2 0.2 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 CCM04748.1 - 0.078 12.0 0.2 0.24 10.4 0.0 1.7 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DASH_Dam1 PF08653.5 CCM04749.1 - 1.3e-17 63.3 0.0 2.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF4519 PF15012.1 CCM04749.1 - 0.019 14.8 2.6 0.031 14.1 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Pneumo_att_G PF05539.6 CCM04749.1 - 1.7 7.9 5.9 2.3 7.4 4.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Daxx PF03344.10 CCM04750.1 - 1.7e-05 23.5 16.0 2.4e-05 23.0 11.1 1.2 1 0 0 1 1 1 1 Daxx Family TFIIF_alpha PF05793.7 CCM04750.1 - 0.002 16.5 20.8 0.003 16.0 14.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 CCM04750.1 - 0.0042 16.4 18.5 0.0069 15.7 12.8 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 CCM04750.1 - 0.0043 15.1 12.3 0.0073 14.4 8.5 1.3 1 0 0 1 1 1 1 CDC45-like protein DUF2457 PF10446.4 CCM04750.1 - 0.053 12.2 19.3 0.097 11.3 13.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 CCM04750.1 - 0.081 10.8 23.2 0.12 10.2 16.1 1.2 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 CCM04750.1 - 0.083 11.3 13.0 0.13 10.7 9.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ATG_C PF09333.6 CCM04750.1 - 0.093 12.8 0.1 1.5 8.9 0.0 2.5 3 0 0 3 3 3 0 ATG C terminal domain Ycf1 PF05758.7 CCM04750.1 - 0.23 9.1 0.0 0.25 9.0 0.0 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CCM04750.1 - 0.76 7.3 4.2 0.91 7.1 2.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRN3 PF05327.6 CCM04750.1 - 2.6 6.0 7.8 3.5 5.6 5.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF605 PF04652.11 CCM04750.1 - 3.8 6.8 22.2 0.086 12.2 8.2 2.1 2 0 0 2 2 2 0 Vta1 like Lin-8 PF03353.10 CCM04750.1 - 7.2 5.7 10.7 13 4.9 7.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cnd1 PF12717.2 CCM04752.1 - 3.9e-62 209.2 4.3 1.4e-57 194.3 0.3 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CCM04752.1 - 2.7e-52 176.8 0.0 2.7e-52 176.8 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 CCM04752.1 - 6e-09 36.0 7.1 0.0099 16.1 0.4 5.7 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 CCM04752.1 - 0.00014 21.6 4.4 6 7.2 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.15 CCM04752.1 - 0.0043 15.4 10.3 0.059 11.6 0.5 3.6 3 2 1 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.1 CCM04752.1 - 0.031 14.7 8.6 1.8 9.1 0.1 5.1 6 0 0 6 6 6 0 HEAT-like repeat PIP5K PF01504.13 CCM04753.1 - 1.7e-87 292.6 0.0 2.6e-87 292.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF1295 PF06966.7 CCM04754.1 - 1.6e-10 40.6 0.1 1.7e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CCM04754.1 - 0.057 13.6 0.1 0.057 13.6 0.0 1.1 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Asp PF00026.18 CCM04756.1 - 3e-45 154.8 6.2 8.1e-45 153.4 4.3 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM04756.1 - 0.0062 16.4 0.4 0.12 12.3 0.1 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCM04756.1 - 0.31 11.5 3.7 0.71 10.4 0.1 3.1 4 0 0 4 4 4 0 Aspartyl protease TAXi_C PF14541.1 CCM04756.1 - 0.75 9.3 4.0 0.41 10.1 0.1 2.3 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Asp PF00026.18 CCM04757.1 - 1.1e-45 156.2 5.9 3e-45 154.8 4.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM04757.1 - 0.00042 20.3 1.2 0.0083 16.0 0.5 2.9 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCM04757.1 - 0.019 15.4 4.5 0.51 10.8 0.1 3.7 3 1 0 3 3 3 0 Aspartyl protease DDE_1 PF03184.14 CCM04757.1 - 0.046 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease TAXi_C PF14541.1 CCM04757.1 - 0.059 12.9 0.0 0.18 11.3 0.0 1.9 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal NMD3 PF04981.8 CCM04758.1 - 1.1e-73 247.3 0.3 1.4e-73 246.9 0.2 1.1 1 0 0 1 1 1 1 NMD3 family Rpr2 PF04032.11 CCM04758.1 - 0.01 15.7 1.2 1.9 8.4 0.2 2.6 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 CCM04758.1 - 0.016 14.9 4.5 0.041 13.7 1.7 2.4 2 1 0 2 2 2 0 Double zinc ribbon NinF PF05810.7 CCM04758.1 - 0.2 11.4 1.9 0.45 10.3 0.6 2.1 2 0 0 2 2 2 0 NinF protein GFA PF04828.9 CCM04758.1 - 0.68 9.9 3.1 5.6 6.9 0.1 3.0 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_3 PF13920.1 CCM04758.1 - 4.1 7.1 6.2 0.35 10.5 0.3 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 CCM04759.1 - 1.9e-20 73.4 0.0 2.5e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04759.1 - 1.5e-08 34.5 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 CCM04759.1 - 0.007 15.3 0.0 0.025 13.5 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Zeta_toxin PF06414.7 CCM04759.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF3639 PF12341.3 CCM04759.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) ADH_zinc_N PF00107.21 CCM04759.1 - 0.12 11.8 0.0 0.3 10.6 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.20 CCM04760.1 - 4.1e-19 69.0 0.0 5.2e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04760.1 - 6e-06 26.0 0.0 6.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM04760.1 - 0.00097 18.9 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM04760.1 - 0.11 12.4 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_4 PF07993.7 CCM04760.1 - 0.16 10.8 0.1 2.9 6.7 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein PEP_mutase PF13714.1 CCM04762.1 - 9.2e-48 162.5 2.2 1.1e-47 162.2 1.5 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 CCM04762.1 - 2e-20 72.5 0.5 2.8e-20 72.0 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family TIM-br_sig_trns PF09370.5 CCM04762.1 - 0.049 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 TIM-barrel signal transduction protein GLE1 PF07817.8 CCM04763.1 - 2.4e-30 105.3 0.0 2.4e-30 105.3 0.0 2.1 2 0 0 2 2 2 1 GLE1-like protein DUF4238 PF14022.1 CCM04763.1 - 0.34 10.1 12.1 0.55 9.4 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Mitofilin PF09731.4 CCM04763.1 - 1.3 7.5 33.8 1.9 7.0 23.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WD40 PF00400.27 CCM04764.1 - 1.4e-48 161.0 30.3 2.9e-12 45.9 0.2 8.7 10 0 0 10 10 10 6 WD domain, G-beta repeat F-box-like PF12937.2 CCM04764.1 - 8.9e-14 50.9 0.7 8.9e-14 50.9 0.5 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM04764.1 - 1.7e-07 30.7 0.4 1.7e-07 30.7 0.3 1.8 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 CCM04764.1 - 5.4e-07 28.1 3.5 0.14 10.2 0.1 4.3 2 1 2 4 4 4 4 Nucleoporin Nup120/160 SWIM PF04434.12 CCM04764.1 - 0.017 14.6 0.1 0.039 13.4 0.1 1.6 1 0 0 1 1 1 0 SWIM zinc finger PQQ_3 PF13570.1 CCM04764.1 - 0.2 11.9 6.8 0.31 11.3 0.0 4.1 5 1 0 5 5 5 0 PQQ-like domain Nucleoporin_N PF08801.6 CCM04764.1 - 0.21 10.2 0.1 1.4 7.6 0.0 2.1 1 1 2 3 3 3 0 Nup133 N terminal like Thymidylat_synt PF00303.14 CCM04765.1 - 2.1e-107 358.1 0.0 2.4e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Cnd3 PF12719.2 CCM04766.1 - 1.8e-77 260.3 0.5 7.6e-77 258.2 0.1 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CCM04766.1 - 4.7e-06 26.7 1.3 0.00078 19.6 0.1 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 CCM04766.1 - 0.0007 19.4 5.6 2.9 8.2 0.0 6.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 CCM04766.1 - 0.25 11.8 2.0 19 5.9 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat adh_short PF00106.20 CCM04769.1 - 9.5e-14 51.6 0.1 1.7e-12 47.5 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04769.1 - 9.8e-06 25.3 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 KR domain LacAB_rpiB PF02502.13 CCM04769.1 - 0.039 13.6 0.4 0.95 9.1 0.2 2.2 1 1 0 2 2 2 0 Ribose/Galactose Isomerase adh_short_C2 PF13561.1 CCM04770.1 - 1e-05 25.4 0.0 0.089 12.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase TFIIE_alpha PF02002.12 CCM04771.1 - 2.7e-17 62.2 0.4 4.8e-17 61.3 0.3 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 CCM04771.1 - 6e-05 22.2 0.4 0.00014 21.1 0.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-C2H2_6 PF13912.1 CCM04771.1 - 0.018 14.9 0.4 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger RecO_N_2 PF13114.1 CCM04771.1 - 0.12 12.0 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 RecO N terminal zf-C2H2 PF00096.21 CCM04771.1 - 0.28 11.6 2.2 0.51 10.7 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type TFIIE-A_C-term PF11521.3 CCM04771.1 - 0.32 10.9 6.9 0.055 13.4 1.1 2.5 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha zf-C4_ClpX PF06689.8 CCM04771.1 - 0.57 9.7 2.2 5.8 6.5 1.6 2.3 1 1 1 2 2 2 0 ClpX C4-type zinc finger UPF0547 PF10571.4 CCM04771.1 - 1.8 8.2 4.0 7.8 6.2 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 LRR_6 PF13516.1 CCM04772.1 - 1.9e-07 30.4 5.9 0.39 10.9 0.0 5.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 CCM04772.1 - 0.0081 15.7 8.9 0.0096 15.5 0.1 3.8 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CCM04772.1 - 0.033 13.9 0.4 0.072 12.8 0.3 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 CCM04772.1 - 0.093 12.4 1.2 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 F-box domain GPI-anchored PF10342.4 CCM04773.1 - 6.5e-08 32.9 0.4 8.2e-08 32.6 0.3 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mem_trans PF03547.13 CCM04774.1 - 2e-42 144.8 0.2 5.3e-37 127.0 0.0 2.3 2 1 0 2 2 2 2 Membrane transport protein GPI-anchored PF10342.4 CCM04775.1 - 3.3e-08 33.8 0.3 3.9e-08 33.6 0.2 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 CCM04776.1 - 6.1e-08 33.0 2.6 7.4e-08 32.7 1.8 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family He_PIG PF05345.7 CCM04776.1 - 0.22 11.5 1.8 11 6.1 0.1 2.3 2 0 0 2 2 2 0 Putative Ig domain Uso1_p115_head PF04869.9 CCM04778.1 - 4.4e-49 166.9 0.0 3e-48 164.2 0.0 2.1 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 CCM04778.1 - 1.1e-09 38.3 17.9 2e-09 37.4 12.4 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Rcd1 PF04078.8 CCM04778.1 - 0.004 16.0 0.1 0.0086 14.9 0.0 1.5 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TMF_TATA_bd PF12325.3 CCM04778.1 - 0.0047 16.6 8.3 0.0093 15.6 5.8 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Cnd1 PF12717.2 CCM04778.1 - 0.02 14.7 1.4 0.091 12.6 0.2 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 COMP PF11598.3 CCM04778.1 - 0.081 13.0 0.7 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Cep57_MT_bd PF06657.8 CCM04778.1 - 0.084 12.8 8.4 0.038 13.9 1.7 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FlxA PF14282.1 CCM04778.1 - 0.28 11.1 7.2 0.53 10.2 5.0 1.4 1 0 0 1 1 1 0 FlxA-like protein IncA PF04156.9 CCM04778.1 - 0.41 10.2 10.3 0.83 9.2 7.2 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CCM04778.1 - 0.7 8.8 11.2 1.4 7.9 7.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 CCM04778.1 - 0.78 10.1 4.2 1.7 9.0 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) OmpH PF03938.9 CCM04778.1 - 0.78 9.6 6.4 2 8.3 4.4 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 CCM04778.1 - 0.91 8.4 6.2 1.4 7.8 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) POX PF07526.6 CCM04778.1 - 0.98 9.6 4.1 1.8 8.8 2.8 1.3 1 0 0 1 1 1 0 Associated with HOX DUF2968 PF11180.3 CCM04778.1 - 2.7 7.3 11.1 5.8 6.2 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) F-box-like PF12937.2 CCM04779.1 - 0.02 14.6 0.0 0.068 12.9 0.0 2.0 1 0 0 1 1 1 0 F-box-like Saccharop_dh PF03435.13 CCM04780.1 - 2.7e-12 46.3 0.3 1.3e-09 37.4 0.0 2.2 1 1 1 2 2 2 2 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CCM04780.1 - 2.6e-08 34.1 0.2 4.4e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM04780.1 - 6.4e-06 25.7 0.0 9.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCM04780.1 - 9.6e-05 22.6 0.0 0.00026 21.2 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 CCM04780.1 - 9.8e-05 22.3 0.3 9.8e-05 22.3 0.2 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM04780.1 - 0.00014 21.5 0.3 0.00043 19.9 0.2 1.8 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 CCM04780.1 - 0.00017 20.8 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CCM04780.1 - 0.0064 15.2 0.0 0.009 14.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CCM04780.1 - 0.077 13.4 0.0 0.3 11.5 0.0 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_M20 PF01546.23 CCM04782.1 - 1.1e-27 96.7 0.0 1.6e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCM04782.1 - 2.3e-08 33.7 0.1 4.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DDE_Tnp_4 PF13359.1 CCM04783.1 - 2.1e-28 98.8 0.0 2.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 CCM04783.1 - 9.4e-09 35.1 0.0 3.1e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 Transposase DDE domain ApoLp-III PF07464.6 CCM04784.1 - 0.034 14.1 0.3 0.049 13.6 0.2 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF641 PF04859.7 CCM04784.1 - 0.3 10.8 3.1 0.42 10.3 1.7 1.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) tRNA-synt_2d PF01409.15 CCM04785.1 - 6e-84 281.1 0.0 5.3e-55 186.3 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 CCM04785.1 - 2.9e-05 23.0 0.1 0.0039 16.0 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 CCM04785.1 - 0.00019 21.0 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pex2_Pex12 PF04757.9 CCM04786.1 - 9.7e-34 116.7 9.9 1.3e-33 116.3 6.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 CCM04786.1 - 0.00014 21.4 2.8 0.00018 21.1 0.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCM04786.1 - 0.0017 18.1 2.5 0.016 14.9 0.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCM04786.1 - 0.0018 17.8 3.1 0.016 14.8 2.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCM04786.1 - 0.0082 16.1 1.2 0.0082 16.1 0.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM04786.1 - 0.0097 15.7 0.9 0.024 14.4 0.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CCM04786.1 - 0.067 13.3 1.1 1.1 9.4 0.8 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCM04786.1 - 0.17 11.6 0.5 0.62 9.8 0.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Cullin PF00888.17 CCM04787.1 - 3.7e-61 207.3 1.1 5.1e-61 206.9 0.6 1.3 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCM04787.1 - 2.6e-23 81.5 5.9 8.5e-23 79.9 3.8 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain Cullin PF00888.17 CCM04788.1 - 4.2e-06 25.5 0.0 4.5e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Cullin family Sulfotransfer_3 PF13469.1 CCM04788.1 - 0.12 13.2 0.2 0.24 12.3 0.0 1.6 2 0 0 2 2 2 0 Sulfotransferase family CDC27 PF09507.5 CCM04789.1 - 4.2e-44 151.4 51.9 7e-43 147.4 36.0 2.1 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 IBN_N PF03810.14 CCM04790.1 - 6.1e-11 42.0 0.1 2.9e-06 27.1 0.2 3.4 2 0 0 2 2 2 2 Importin-beta N-terminal domain Slx4 PF09494.5 CCM04791.1 - 1.3e-05 24.8 0.4 2.6e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Slx4 endonuclease Mur_ligase_M PF08245.7 CCM04792.1 - 0.00063 19.8 0.2 0.041 13.9 0.2 2.7 1 1 0 1 1 1 1 Mur ligase middle domain Fe-ADH PF00465.14 CCM04793.1 - 1.6e-87 293.5 0.0 2e-87 293.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CCM04793.1 - 5.4e-10 38.9 0.0 6.4e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase ATP-synt_C PF00137.16 CCM04793.1 - 0.37 10.7 2.6 0.54 10.1 1.0 1.8 2 0 0 2 2 2 0 ATP synthase subunit C Asp PF00026.18 CCM04794.1 - 1.1e-36 126.6 0.6 2.5e-35 122.2 0.4 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM04794.1 - 0.00081 19.3 1.5 0.016 15.1 0.3 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal PPR_2 PF13041.1 CCM04795.1 - 4e-15 55.5 0.5 1.3e-07 31.4 0.0 4.7 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.15 CCM04795.1 - 7.2e-05 22.5 6.1 4.4 7.5 0.0 6.1 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 CCM04795.1 - 0.081 12.4 3.7 9.2 5.8 0.0 3.9 4 0 0 4 4 4 0 PPR repeat PPR_3 PF13812.1 CCM04795.1 - 0.32 11.3 8.5 1e+02 3.5 0.0 6.5 8 1 0 8 8 8 0 Pentatricopeptide repeat domain DAO PF01266.19 CCM04796.1 - 2.3e-22 79.4 0.0 3.4e-22 78.8 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase VQ PF05678.9 CCM04796.1 - 0.64 9.1 2.0 16 4.6 0.1 2.4 2 0 0 2 2 2 0 VQ motif TPR_11 PF13414.1 CCM04797.1 - 2.1e-23 81.7 8.4 3.8e-15 55.2 0.1 2.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 CCM04797.1 - 1.6e-14 52.8 6.2 8.7e-07 28.2 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCM04797.1 - 3.1e-10 39.1 3.7 5.1e-05 22.8 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCM04797.1 - 0.0011 19.4 0.0 0.088 13.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCM04797.1 - 0.0015 18.4 0.8 0.084 12.8 0.1 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM04797.1 - 0.0045 16.6 0.2 2.8 7.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CCM04797.1 - 0.008 16.2 1.3 0.015 15.4 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CCM04797.1 - 0.018 15.3 0.0 1.3 9.4 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCM04797.1 - 0.02 15.0 0.3 1.2 9.4 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1666 PF07891.7 CCM04797.1 - 0.044 13.1 0.5 0.092 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) TPR_8 PF13181.1 CCM04797.1 - 0.067 12.9 0.1 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Spindle_Spc25 PF08234.7 CCM04798.1 - 1.9e-19 69.4 1.4 2.4e-19 69.1 0.2 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4200 PF13863.1 CCM04798.1 - 0.013 15.4 9.4 0.019 14.9 5.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) IncA PF04156.9 CCM04798.1 - 0.034 13.7 8.9 0.044 13.3 6.2 1.2 1 0 0 1 1 1 0 IncA protein RICH PF05062.7 CCM04798.1 - 0.13 12.3 2.2 0.28 11.3 1.4 1.6 1 1 0 1 1 1 0 RICH domain Ribosomal_S7e PF01251.13 CCM04799.1 - 3.7e-86 287.4 4.0 4.1e-86 287.3 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.17 CCM04800.1 - 4.7e-47 159.3 0.0 8.8e-44 148.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCM04800.1 - 2.1e-21 76.5 0.0 4.4e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM04800.1 - 3.5e-11 42.6 0.0 8.1e-11 41.4 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCM04800.1 - 2.4e-06 27.4 0.0 4.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCM04800.1 - 0.00022 20.4 0.0 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCM04800.1 - 0.00075 18.7 0.4 0.002 17.3 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CCM04800.1 - 0.0021 17.5 0.1 0.062 12.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CCM04800.1 - 0.0051 16.9 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCM04800.1 - 0.0064 16.3 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Tir_receptor_C PF07489.6 CCM04800.1 - 0.015 15.0 0.1 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF258 PF03193.11 CCM04800.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CCM04800.1 - 0.064 12.9 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 CCM04800.1 - 0.15 11.0 0.1 0.5 9.3 0.0 1.7 2 0 0 2 2 2 0 Septin FeoB_N PF02421.13 CCM04800.1 - 0.19 11.0 0.2 1.9 7.7 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B AMMECR1 PF01871.12 CCM04801.1 - 7.1e-38 129.4 0.0 7.2e-26 90.3 0.0 2.0 2 0 0 2 2 2 2 AMMECR1 RXT2_N PF08595.6 CCM04801.1 - 0.099 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Ribosomal_L3 PF00297.17 CCM04802.1 - 4.2e-121 403.3 8.0 5.8e-121 402.8 5.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 PPR PF01535.15 CCM04802.1 - 1.7e-07 30.7 1.4 0.0096 15.8 0.0 5.7 6 0 0 6 6 6 1 PPR repeat PPR_2 PF13041.1 CCM04802.1 - 3.9e-07 29.9 2.1 0.044 13.7 0.0 4.5 4 1 1 5 5 5 2 PPR repeat family PPR_1 PF12854.2 CCM04802.1 - 3.8e-05 23.0 0.5 0.18 11.3 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 CCM04802.1 - 0.00013 21.9 4.6 0.41 11.0 0.1 5.7 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TPR_16 PF13432.1 CCM04802.1 - 0.029 15.0 2.7 47 4.8 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCM04802.1 - 0.03 14.9 2.2 55 4.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MRC1 PF09444.5 CCM04803.1 - 3.7e-21 75.9 21.9 3.7e-21 75.9 15.2 4.2 4 0 0 4 4 4 1 MRC1-like domain Tho2 PF11262.3 CCM04804.1 - 5.8e-62 209.4 0.0 9.7e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CCM04804.1 - 2.9e-25 87.8 0.0 6.1e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit GTP_cyclohydroI PF01227.17 CCM04805.1 - 3.3e-74 248.0 0.2 4e-74 247.7 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CCM04805.1 - 0.00042 20.2 0.0 0.0011 18.8 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 CCM04805.1 - 0.045 13.5 0.5 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain ABC_tran PF00005.22 CCM04806.1 - 6.3e-16 58.9 0.0 1.8e-15 57.4 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCM04806.1 - 2.5e-06 27.6 0.0 2.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 CCM04806.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CCM04806.1 - 0.007 15.4 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 CCM04806.1 - 0.016 14.4 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 CCM04806.1 - 0.15 10.4 0.0 0.27 9.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L12 PF00542.14 CCM04806.1 - 0.22 11.5 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Ank_2 PF12796.2 CCM04807.1 - 7.6e-45 151.1 3.1 8e-13 48.5 0.0 4.4 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Pex2_Pex12 PF04757.9 CCM04807.1 - 6.3e-43 146.8 5.2 2.5e-42 144.8 3.6 1.9 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region Ank PF00023.25 CCM04807.1 - 2.1e-31 106.1 10.2 0.00031 20.3 0.1 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 CCM04807.1 - 2.1e-28 98.1 5.7 1.4e-08 35.0 0.1 5.2 5 1 1 6 6 5 4 Ankyrin repeats (many copies) SPX PF03105.14 CCM04807.1 - 1.3e-27 97.3 0.1 1.7e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 SPX domain Ank_5 PF13857.1 CCM04807.1 - 2.9e-23 81.3 6.5 2.4e-06 27.5 0.1 6.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM04807.1 - 1.3e-22 77.6 5.1 0.00086 19.3 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat GDPD PF03009.12 CCM04807.1 - 5.1e-12 45.8 0.0 1.5e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family zf-C3HC4_2 PF13923.1 CCM04807.1 - 0.025 14.5 0.1 0.077 13.0 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCM04807.1 - 0.29 10.8 0.0 0.78 9.4 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM04807.1 - 0.3 11.0 0.2 0.64 9.9 0.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3722 PF12519.3 CCM04810.1 - 1e-89 300.1 4.4 1.2e-67 227.9 0.0 2.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3722) Paramyx_P_V_C PF03210.8 CCM04811.1 - 1.2 8.9 4.2 3.9 7.3 0.1 2.8 3 1 0 3 3 3 0 Paramyxovirus P/V phosphoprotein C-terminal Brix PF04427.13 CCM04812.1 - 1.4e-36 125.9 0.7 5.2e-35 120.8 0.1 2.2 2 0 0 2 2 2 2 Brix domain LSM PF01423.17 CCM04812.1 - 8.4e-13 47.6 0.0 1.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 LSM domain Peptidase_M18 PF02127.10 CCM04813.1 - 6.7e-150 499.3 0.0 7.6e-150 499.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CCM04813.1 - 1.5e-07 30.5 0.1 6e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase WD40 PF00400.27 CCM04814.1 - 4.4e-71 232.4 23.2 5.7e-09 35.5 0.0 11.7 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 CCM04814.1 - 4.8e-20 71.5 0.2 8.2e-20 70.7 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CCM04814.1 - 2.9e-06 25.7 4.9 0.36 8.9 0.0 4.7 4 2 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCM04814.1 - 1.1e-05 24.4 5.9 0.024 13.3 0.2 5.4 4 2 2 6 6 6 2 Nup133 N terminal like BBS2_Mid PF14783.1 CCM04814.1 - 0.0029 17.3 0.1 12 5.6 0.0 5.6 5 2 1 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 CCM04814.1 - 0.0092 15.4 0.0 31 4.1 0.0 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 CCM04814.1 - 0.1 12.2 0.2 5 6.7 0.0 3.3 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A DPBB_1 PF03330.13 CCM04815.1 - 2.4e-07 30.6 0.0 7e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cys_Met_Meta_PP PF01053.15 CCM04816.1 - 1.2e-55 188.3 0.0 4.4e-55 186.5 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Acyltransferase PF01553.16 CCM04817.1 - 0.075 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase SNARE_assoc PF09335.6 CCM04818.1 - 4e-14 52.8 8.8 4e-14 52.8 6.1 3.2 3 1 0 3 3 3 1 SNARE associated Golgi protein HAMP PF00672.20 CCM04818.1 - 0.0058 16.7 0.6 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 HAMP domain Alg6_Alg8 PF03155.10 CCM04819.1 - 3.1e-132 441.7 32.6 4.4e-132 441.2 22.6 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Syntaxin-18_N PF10496.4 CCM04819.1 - 4.3e-10 39.2 0.2 1.1e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus VMA21 PF09446.5 CCM04820.1 - 3.5e-12 46.0 5.8 5e-12 45.5 4.0 1.2 1 0 0 1 1 1 1 VMA21-like domain UPF0104 PF03706.8 CCM04820.1 - 0.0041 16.4 0.3 0.0044 16.3 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF1469 PF07332.6 CCM04820.1 - 0.017 14.8 1.2 0.019 14.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF973 PF06157.6 CCM04820.1 - 0.076 11.9 0.8 0.085 11.8 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) PhaG_MnhG_YufB PF03334.9 CCM04820.1 - 0.17 11.9 2.0 0.43 10.6 0.1 2.0 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Ribonuc_red_sm PF00268.16 CCM04821.1 - 3e-120 400.4 0.4 3.6e-120 400.1 0.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 CCM04822.1 - 4.7e-118 393.2 3.4 5.7e-118 392.9 2.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TGS PF02824.16 CCM04823.1 - 2.4e-24 84.9 0.1 4.3e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CCM04823.1 - 5.8e-18 64.9 0.2 2.5e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCM04823.1 - 2.9e-08 33.1 0.0 6.4e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCM04823.1 - 0.0055 16.5 0.6 3.3 7.5 0.0 2.6 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 CCM04823.1 - 0.0093 14.7 0.2 0.02 13.6 0.2 1.5 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 CCM04823.1 - 0.021 15.3 0.0 0.065 13.7 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein Mor PF08765.6 CCM04823.1 - 0.022 14.5 0.1 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 Mor transcription activator family Peptidase_S24 PF00717.18 CCM04825.1 - 4.2e-10 39.1 0.1 9.7e-10 37.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CCM04825.1 - 0.0014 18.1 0.0 0.27 10.7 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 ATE_C PF04377.10 CCM04826.1 - 3.3e-27 95.0 0.2 4.8e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus mRNA_cap_enzyme PF01331.14 CCM04826.1 - 0.065 12.9 0.1 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain WD40 PF00400.27 CCM04827.1 - 0.00072 19.3 0.7 0.26 11.2 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 CCM04827.1 - 0.12 11.4 0.0 8.7 5.3 0.0 2.1 2 0 0 2 2 2 0 CPSF A subunit region DUF1513 PF07433.6 CCM04827.1 - 0.13 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF839 PF05787.8 CCM04827.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) EF-hand_7 PF13499.1 CCM04829.1 - 6.9e-25 86.9 5.0 2.7e-15 56.2 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCM04829.1 - 1.1e-24 83.7 9.7 4e-08 31.9 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 CCM04829.1 - 5.2e-20 69.4 5.1 3.6e-06 26.4 0.1 5.0 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 CCM04829.1 - 5.8e-14 50.6 9.1 0.00022 20.4 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CCM04829.1 - 2.2e-11 43.1 7.9 7.5e-05 22.2 0.7 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 CCM04829.1 - 1.9e-06 27.5 3.1 0.21 11.3 0.0 3.8 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CCM04829.1 - 8.8e-05 22.5 1.3 0.013 15.5 0.1 3.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CCM04829.1 - 0.015 14.9 1.1 12 5.7 0.0 3.9 4 0 0 4 4 4 0 EF hand EF-hand_9 PF14658.1 CCM04829.1 - 0.02 14.7 1.1 0.38 10.7 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain S10_plectin PF03501.10 CCM04829.1 - 0.026 14.3 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.6 CCM04829.1 - 0.059 13.4 0.0 2 8.5 0.0 2.7 3 0 0 3 3 3 0 EF hand DUF106 PF01956.11 CCM04830.1 - 6.2e-48 162.4 0.1 8.7e-48 162.0 0.0 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 Sec63 PF02889.11 CCM04831.1 - 2.4e-84 283.2 0.0 3.3e-84 282.8 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CCM04831.1 - 3.3e-29 101.5 0.1 1.7e-11 43.9 0.0 4.3 3 1 1 4 4 4 3 DEAD/DEAH box helicase ResIII PF04851.10 CCM04831.1 - 3.2e-08 33.6 0.0 0.038 13.8 0.0 3.4 2 1 1 3 3 3 3 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCM04831.1 - 1.5e-07 31.1 0.0 5.2e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCM04831.1 - 4.2e-07 30.1 0.6 0.0085 16.2 0.2 3.3 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 CCM04831.1 - 7.9e-05 22.8 0.1 0.026 14.7 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCM04831.1 - 0.00058 19.3 0.1 1.5 8.1 0.0 3.9 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 CCM04831.1 - 0.00082 18.8 2.1 4.3 6.7 0.0 3.9 3 1 0 3 3 3 2 IstB-like ATP binding protein T2SE PF00437.15 CCM04831.1 - 0.0027 16.6 0.0 0.53 9.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 CCM04831.1 - 0.0041 16.6 0.0 2 7.7 0.0 3.0 2 1 1 3 3 3 1 AAA-like domain PhoH PF02562.11 CCM04831.1 - 0.0043 16.3 0.1 3.1 6.9 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 CCM04831.1 - 0.0058 16.3 0.1 0.45 10.3 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CCM04831.1 - 0.018 14.5 0.2 2.9 7.3 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.12 CCM04831.1 - 0.022 14.6 0.6 0.9 9.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_11 PF13086.1 CCM04831.1 - 0.08 12.5 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.16 CCM04832.1 - 4.3e-64 216.7 0.0 4.9e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CCM04832.1 - 2.9e-08 33.1 0.0 4.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CCM04832.1 - 1.3e-06 27.0 0.0 2.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CCM04832.1 - 0.00014 21.1 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCM04832.1 - 0.00049 18.9 0.0 0.0046 15.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Ank PF00023.25 CCM04833.1 - 1.8e-32 109.5 1.1 6.6e-07 28.8 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CCM04833.1 - 3.1e-32 109.8 3.9 6.4e-10 38.9 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCM04833.1 - 7.7e-32 109.1 6.8 1.1e-12 48.1 0.3 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCM04833.1 - 9.4e-32 109.2 0.2 4.2e-21 75.0 0.0 4.3 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCM04833.1 - 2.2e-24 83.0 0.2 9.2e-05 22.3 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.16 CCM04833.1 - 0.00015 21.5 0.7 0.00015 21.5 0.5 2.3 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.1 CCM04833.1 - 0.00042 20.0 4.7 0.00089 19.0 0.8 2.5 2 0 0 2 2 2 1 Ring finger domain Pex24p PF06398.6 CCM04833.1 - 0.11 11.3 0.2 0.23 10.2 0.1 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Cir_N PF10197.4 CCM04834.1 - 6.4 6.8 8.7 0.77 9.8 2.2 2.2 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR PI31_Prot_N PF11566.3 CCM04835.1 - 2.8e-26 91.9 0.0 3.5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 CCM04835.1 - 8.6e-09 35.9 19.0 8.6e-09 35.9 13.2 3.4 3 0 0 3 3 3 1 PI31 proteasome regulator DEAD PF00270.24 CCM04836.1 - 5.9e-47 159.2 0.0 7.9e-46 155.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM04836.1 - 1.5e-23 82.4 0.0 3.8e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCM04836.1 - 0.025 13.4 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Sugar_tr PF00083.19 CCM04837.1 - 3.6e-105 352.1 24.6 4.2e-105 351.9 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM04837.1 - 9.7e-22 77.1 35.0 1.4e-15 56.8 6.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CCM04837.1 - 0.0082 16.1 3.9 0.16 11.9 0.3 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) MFS_1_like PF12832.2 CCM04837.1 - 0.011 15.4 1.2 1.1 9.0 0.2 2.9 2 0 0 2 2 2 0 MFS_1 like family Herpes_LMP1 PF05297.6 CCM04837.1 - 0.91 8.3 5.3 1.7 7.5 3.7 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-MYND PF01753.13 CCM04839.1 - 0.00093 19.0 3.3 0.00093 19.0 2.3 1.9 2 0 0 2 2 2 1 MYND finger DUF1793 PF08760.6 CCM04841.1 - 5.9e-20 71.8 0.1 8.2e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) MFS_1 PF07690.11 CCM04842.1 - 1.5e-29 102.8 16.3 2.3e-29 102.2 9.5 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Cyt_c_ox_IV PF12270.3 CCM04842.1 - 0.47 10.1 10.0 2.2 8.0 1.1 3.6 4 0 0 4 4 4 0 Cytochrome c oxidase subunit IV Ytp1 PF10355.4 CCM04843.1 - 1.3e-89 299.9 9.1 2.3e-89 299.2 6.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CCM04843.1 - 8e-14 51.0 0.2 8e-14 51.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) SAE2 PF08573.5 CCM04843.1 - 0.066 13.9 0.2 17 6.1 0.1 2.4 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus ChaC PF04752.7 CCM04844.1 - 1.1e-51 175.3 0.0 1.2e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein AIG2 PF06094.7 CCM04844.1 - 0.0081 16.6 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family UbiA PF01040.13 CCM04845.1 - 8.3e-36 123.5 16.0 1e-35 123.2 11.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ost4 PF10215.4 CCM04845.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Oligosaccaryltransferase Rho_GDI PF02115.12 CCM04846.1 - 2.2e-54 183.9 0.0 2.7e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.10 CCM04846.1 - 0.079 13.2 0.1 0.34 11.1 0.1 2.1 1 1 0 1 1 1 0 ML domain Packaging_FI PF14000.1 CCM04847.1 - 0.0039 17.3 0.2 0.0075 16.4 0.1 1.5 1 0 0 1 1 1 1 DNA packaging protein FI MbeD_MobD PF04899.7 CCM04847.1 - 0.07 13.0 1.0 0.74 9.7 0.0 2.5 1 1 1 2 2 2 0 MbeD/MobD like Nsp1_C PF05064.8 CCM04848.1 - 1.6e-32 111.6 0.1 2.9e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 CCM04848.1 - 3e-13 49.9 193.6 1.7e-05 25.0 33.6 6.1 1 1 4 5 5 5 3 Nucleoporin FG repeat region CDC27 PF09507.5 CCM04848.1 - 0.07 12.3 10.5 0.12 11.5 7.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Tetraspannin PF00335.15 CCM04849.1 - 6 6.0 9.3 12 5.1 6.5 1.4 1 0 0 1 1 1 0 Tetraspanin family Nup88 PF10168.4 CCM04850.1 - 1.7e-18 65.8 1.3 7.4e-09 34.0 0.0 3.1 2 1 0 2 2 2 2 Nuclear pore component ABC_tran_2 PF12848.2 CCM04850.1 - 0.12 12.2 3.1 0.32 10.8 2.2 1.7 1 0 0 1 1 1 0 ABC transporter Proteasome PF00227.21 CCM04851.1 - 4.3e-46 156.6 0.0 5.3e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCM04851.1 - 3.8e-13 48.4 0.1 7.3e-13 47.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SAC3_GANP PF03399.11 CCM04852.1 - 4.6e-33 114.5 0.0 6.1e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCM04852.1 - 8.4e-33 113.1 0.1 1.3e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Proteasome PF00227.21 CCM04853.1 - 4e-46 156.7 0.1 4.5e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF448 PF04296.8 CCM04854.1 - 0.027 14.0 0.1 0.41 10.3 0.1 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF448) GFO_IDH_MocA PF01408.17 CCM04855.1 - 1.3e-20 74.1 0.3 2.1e-20 73.3 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCM04855.1 - 1.4e-07 31.2 0.0 1.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 CCM04855.1 - 0.014 15.8 0.1 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CCM04855.1 - 0.016 14.6 0.0 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 CCM04855.1 - 0.046 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 CCM04855.1 - 0.11 11.5 0.3 0.16 10.9 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1793 PF08760.6 CCM04856.1 - 1.9e-21 76.6 0.1 2.5e-21 76.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Herpes_gE PF02480.11 CCM04856.1 - 0.16 10.1 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E adh_short PF00106.20 CCM04858.1 - 6.5e-26 91.2 0.1 9.8e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM04858.1 - 1.6e-12 47.7 0.0 2.2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM04858.1 - 2.1e-09 37.3 0.1 5.5e-09 35.9 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM04858.1 - 2.2e-05 23.9 0.0 4.8e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM04858.1 - 0.00013 22.0 0.2 0.00017 21.6 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CCM04858.1 - 0.00049 19.0 0.1 0.00081 18.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Arabinose_Isome PF02610.10 CCM04858.1 - 0.046 12.6 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 L-arabinose isomerase DUF347 PF03988.7 CCM04859.1 - 0.028 14.2 0.6 0.072 12.9 0.4 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) cNMP_binding PF00027.24 CCM04860.1 - 9.8e-36 121.4 0.0 2.3e-18 65.7 0.0 2.5 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CCM04860.1 - 2.5e-12 45.9 0.8 1.2e-11 43.8 0.2 2.2 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit ubiquitin PF00240.18 CCM04861.1 - 3e-06 26.5 0.0 5.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 CCM04861.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UPRTase PF14681.1 CCM04862.1 - 4.8e-70 234.9 0.0 5.5e-70 234.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CCM04862.1 - 0.00012 21.8 0.0 0.00015 21.4 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_1 PF00667.15 CCM04863.1 - 3.9e-50 170.3 0.0 5.8e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CCM04863.1 - 4e-10 40.2 0.0 8.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCM04863.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Transketolase_C PF02780.15 CCM04863.1 - 0.086 12.7 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain NUDIX PF00293.23 CCM04864.1 - 2.9e-12 46.3 0.2 1.1e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain GFO_IDH_MocA PF01408.17 CCM04865.1 - 4.1e-22 78.9 0.0 8.2e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCM04865.1 - 1.5e-08 34.3 0.0 2.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 CCM04865.1 - 0.0024 18.1 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 CCM04865.1 - 0.021 15.2 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 CCM04865.1 - 0.085 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain GFO_IDH_MocA PF01408.17 CCM04866.1 - 3.6e-20 72.6 0.1 7.3e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCM04866.1 - 2.3e-09 37.0 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 CCM04866.1 - 0.00028 21.1 0.0 0.00046 20.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 CCM04866.1 - 0.0022 18.3 0.1 0.0039 17.5 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 CCM04866.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_8 PF05148.10 CCM04867.1 - 4.7e-61 206.2 0.0 1.3e-31 109.9 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_23 PF13489.1 CCM04867.1 - 5.1e-06 26.2 0.0 8.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM04867.1 - 1.4e-05 25.5 0.1 0.0003 21.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM04867.1 - 0.0027 17.2 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM04867.1 - 0.054 13.8 0.1 23 5.4 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.2 CCM04867.1 - 0.11 13.1 0.1 0.5 10.9 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain AAA_10 PF12846.2 CCM04868.1 - 2.6e-12 46.8 0.0 5.1e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 CCM04868.1 - 9e-08 31.8 0.0 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 CCM04868.1 - 3.7e-06 27.0 0.0 0.013 15.6 0.0 3.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CCM04868.1 - 0.0024 18.0 0.1 0.11 12.6 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 CCM04868.1 - 0.014 15.1 0.0 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CCM04868.1 - 0.019 14.4 0.0 0.65 9.4 0.0 2.5 2 1 0 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.24 CCM04868.1 - 0.11 11.9 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase Ribosomal_S3Ae PF01015.13 CCM04869.1 - 2.3e-85 284.8 4.2 2.7e-85 284.6 2.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family mRNA_cap_C PF03919.10 CCM04869.1 - 0.028 14.7 0.2 0.054 13.8 0.1 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Abhydro_lipase PF04083.11 CCM04869.1 - 0.045 13.1 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Autophagy_act_C PF03987.10 CCM04870.1 - 7.7e-13 48.4 1.0 1.9e-12 47.1 0.7 1.7 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Thiolase_N PF00108.18 CCM04871.1 - 2.9e-88 295.2 1.5 4e-88 294.8 1.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCM04871.1 - 5e-40 135.7 1.5 5e-40 135.7 1.1 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCM04871.1 - 0.0026 17.2 5.7 0.049 13.1 2.9 2.3 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 CCM04871.1 - 0.054 13.5 0.1 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 CCM04871.1 - 0.15 11.7 1.9 1.2 8.8 0.6 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.11 CCM04872.1 - 4.3e-33 114.4 15.4 4.3e-33 114.4 10.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily BTB PF00651.26 CCM04873.1 - 0.0015 18.4 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.11 CCM04874.1 - 2.3e-19 69.3 8.0 2.8e-19 69.0 5.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 CCM04875.1 - 8.4e-07 28.0 3.8 9.4e-07 27.8 2.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily EcsB PF05975.7 CCM04875.1 - 0.011 14.1 1.3 0.014 13.9 0.9 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB DUF1435 PF07256.7 CCM04875.1 - 0.11 12.4 1.5 0.2 11.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) MFS_2 PF13347.1 CCM04875.1 - 0.2 10.0 6.3 1.9 6.8 2.4 2.0 1 1 1 2 2 2 0 MFS/sugar transport protein DUF3464 PF11947.3 CCM04875.1 - 0.22 10.9 0.5 0.38 10.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Atg14 PF10186.4 CCM04876.1 - 0.083 11.8 2.7 0.12 11.3 1.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CAF-1_p150 PF11600.3 CCM04876.1 - 4.1 6.7 14.7 7.3 5.8 10.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4337 PF14235.1 CCM04876.1 - 4.5 7.0 5.2 7.1 6.4 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DIOX_N PF14226.1 CCM04877.1 - 3.4e-23 82.3 0.2 5.5e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM04877.1 - 3.8e-19 68.7 0.0 7.9e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Spermine_synth PF01564.12 CCM04878.1 - 5.6e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 CCM04878.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM04878.1 - 0.012 16.1 0.0 0.021 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Alpha-amylase_C PF02806.13 CCM04879.1 - 1.4e-22 79.6 0.1 4.2e-22 78.0 0.1 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CCM04879.1 - 4e-18 65.8 0.0 2.9e-13 49.9 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 CCM04879.1 - 3.1e-14 52.7 0.0 9.1e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Acetyltransf_9 PF13527.1 CCM04879.1 - 0.074 12.9 0.5 7.8 6.3 0.2 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Peptidase_M28 PF04389.12 CCM04880.1 - 8.1e-15 55.0 0.1 1.8e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CCM04880.1 - 1e-11 44.4 0.0 8.7e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CCM04880.1 - 5.7e-05 22.7 0.2 0.00013 21.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Polysacc_deac_1 PF01522.16 CCM04881.1 - 2.7e-20 72.2 0.0 6.3e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase ATG11 PF10377.4 CCM04884.1 - 5.7e-33 113.5 0.1 1.3e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 11 Sugar_tr PF00083.19 CCM04885.1 - 4e-65 220.1 19.3 4.5e-65 219.9 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM04885.1 - 9.9e-12 44.2 16.9 9.9e-12 44.2 11.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Gate PF07670.9 CCM04885.1 - 6.8 6.6 9.3 32 4.4 6.5 2.1 1 1 0 1 1 1 0 Nucleoside recognition ADH_zinc_N PF00107.21 CCM04886.1 - 0.0012 18.4 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM04886.1 - 0.0031 18.4 0.0 0.0032 18.3 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM04887.1 - 1.7e-28 98.5 0.7 2.7e-28 97.8 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM04887.1 - 1e-08 34.8 0.5 1e-08 34.8 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase p450 PF00067.17 CCM04888.1 - 6.5e-88 295.2 0.0 1.1e-87 294.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 CCM04888.1 - 5.4e-28 97.9 0.0 8.6e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCM04888.1 - 2.3e-22 79.5 0.1 9e-22 77.6 0.0 2.1 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.16 CCM04888.1 - 3.3e-10 40.4 0.0 7.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 CCM04888.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 CCM04888.1 - 0.028 14.4 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain FAD_binding_6 PF00970.19 CCM04888.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EphA2_TM PF14575.1 CCM04889.1 - 0.0018 18.5 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 CCM04889.1 - 0.0056 15.9 0.3 0.011 15.0 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 CCM04889.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Glycophorin A Protocadherin PF08374.6 CCM04889.1 - 0.087 12.4 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Protocadherin Yip1 PF04893.12 CCM04889.1 - 0.11 11.9 2.0 0.63 9.5 0.0 2.4 2 1 0 2 2 2 0 Yip1 domain DUF1517 PF07466.6 CCM04889.1 - 0.52 9.2 5.8 0.089 11.7 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Gly-zipper_YMGG PF13441.1 CCM04889.1 - 0.62 9.6 12.2 1.6 8.3 8.4 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper FMO-like PF00743.14 CCM04891.1 - 1.6e-34 119.0 0.0 6.5e-29 100.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCM04891.1 - 4e-15 56.4 0.0 7.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCM04891.1 - 2.8e-06 27.1 0.4 0.58 9.9 0.0 3.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCM04891.1 - 3e-06 27.2 0.0 0.0011 18.8 0.0 3.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM04891.1 - 0.00021 20.3 0.0 0.0011 17.9 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 CCM04891.1 - 0.019 14.0 0.1 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Sec20 PF03908.8 CCM04892.1 - 2.7e-18 65.4 1.6 2.7e-18 65.4 1.1 2.6 3 1 0 3 3 3 1 Sec20 DUF1204 PF06721.6 CCM04892.1 - 0.031 13.5 5.2 0.056 12.6 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) HBS1_N PF08938.5 CCM04892.1 - 0.095 12.8 4.5 8.9 6.5 1.8 3.6 2 1 0 2 2 2 0 HBS1 N-terminus KxDL PF10241.4 CCM04892.1 - 0.46 10.4 4.4 0.17 11.8 0.2 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF3829 PF12889.2 CCM04892.1 - 6 5.9 6.8 0.88 8.7 1.8 1.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3829) Mito_carr PF00153.22 CCM04893.1 - 1.6e-54 181.5 3.4 1.9e-20 72.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_zinc_N PF00107.21 CCM04894.1 - 4.7e-14 52.0 0.0 9.3e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM04894.1 - 1e-10 41.3 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PHD PF00628.24 CCM04895.1 - 1.2e-09 37.6 0.6 2.5e-09 36.6 0.4 1.4 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.19 CCM04895.1 - 0.00058 19.4 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Sugar_tr PF00083.19 CCM04896.1 - 4.3e-70 236.5 26.6 5.5e-70 236.1 18.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM04896.1 - 8.2e-24 83.9 28.2 8.2e-24 83.9 19.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Rho_N PF07498.7 CCM04896.1 - 0.00012 21.7 0.2 0.00012 21.7 0.1 1.7 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain Armet PF10208.4 CCM04896.1 - 0.024 14.2 0.1 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding zf-HIT PF04438.11 CCM04896.1 - 0.086 12.5 1.0 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-C3HC4_3 PF13920.1 CCM04896.1 - 0.11 12.1 0.3 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF221 PF02714.10 CCM04897.1 - 2.5e-102 342.0 21.8 3.5e-102 341.5 15.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCM04897.1 - 2.7e-25 88.7 1.7 1.2e-24 86.6 1.2 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CCM04897.1 - 2.5e-13 49.7 0.0 5.2e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CCM04897.1 - 1.7e-11 44.4 1.7 4.4e-11 43.1 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) F-box-like PF12937.2 CCM04900.1 - 0.0042 16.7 0.1 0.0093 15.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM04900.1 - 0.076 12.6 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 F-box domain Lactamase_B PF00753.22 CCM04901.1 - 2.4e-09 37.1 1.9 5.5e-09 35.9 1.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCM04901.1 - 0.00029 20.4 0.2 0.00036 20.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2668 PF10873.3 CCM04901.1 - 0.14 12.3 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) LRR_4 PF12799.2 CCM04902.1 - 0.041 13.5 0.5 0.67 9.6 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Phage_ASH PF10554.4 CCM04902.1 - 0.05 13.9 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Ash protein family F-box-like PF12937.2 CCM04902.1 - 0.075 12.7 0.2 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 F-box-like Sugar_tr PF00083.19 CCM04904.1 - 3.7e-24 85.1 7.6 4.2e-24 84.9 5.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter COX2-transmemb PF09125.5 CCM04904.1 - 3.5 7.2 7.2 0.7 9.4 0.8 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane SH3_1 PF00018.23 CCM04906.1 - 3.6e-14 51.8 0.0 6.9e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCM04906.1 - 2.9e-13 49.1 0.2 6.1e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCM04906.1 - 7.2e-11 41.4 0.0 1.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 CCM04906.1 - 2.7e-07 30.3 0.2 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 2 WW domain Skp1_POZ PF03931.10 CCM04906.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain RasGEF PF00617.14 CCM04907.1 - 5.1e-54 182.8 0.2 7.8e-54 182.2 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCM04907.1 - 1.1e-18 67.2 0.0 4.5e-18 65.2 0.0 2.1 2 1 0 2 2 2 1 RasGEF N-terminal motif Hydrolase PF00702.21 CCM04909.1 - 3.5e-12 47.2 0.0 1.8e-11 44.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCM04909.1 - 1.8e-11 44.5 0.1 6.6e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCM04909.1 - 4.5e-08 32.6 0.0 1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCM04909.1 - 0.0059 16.8 0.0 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 CCM04910.1 - 5.9e-14 51.4 0.0 8.3e-14 50.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1825 PF08855.5 CCM04910.1 - 0.12 12.3 0.1 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) BHD_3 PF10405.4 CCM04912.1 - 1.7e-28 98.1 0.1 3.1e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CCM04912.1 - 1.6e-23 82.7 0.0 4.9e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 CCM04912.1 - 2e-18 65.6 0.0 6.3e-18 64.0 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CCM04912.1 - 1.2e-11 44.7 0.1 1.2e-11 44.7 0.1 3.4 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CCM04912.1 - 3e-06 27.4 0.0 3.5e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 Transglutaminase-like superfamily FAM176 PF14851.1 CCM04912.1 - 1.9 8.1 0.0 1.9 8.1 0.0 3.4 3 0 0 3 3 3 0 FAM176 family DNA_pol_viral_N PF00242.12 CCM04912.1 - 7.4 5.4 8.5 13 4.6 5.9 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain GCD14 PF08704.5 CCM04913.1 - 8.9e-81 271.0 0.2 7.4e-58 195.9 0.0 2.9 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 CCM04913.1 - 0.00097 19.1 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CCM04913.1 - 0.049 14.4 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CCM04913.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PAS_3 PF08447.6 CCM04914.1 - 3.4e-07 30.2 0.0 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 CCM04914.1 - 3.1e-05 23.7 0.0 0.00027 20.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 CCM04914.1 - 0.00079 19.3 0.0 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.1 CCM04914.1 - 0.004 17.5 0.0 0.036 14.4 0.0 2.1 2 0 0 2 2 2 1 PAS domain p450 PF00067.17 CCM04915.1 - 1.4e-49 168.8 0.0 2.1e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.24 CCM04917.1 - 8.7e-20 70.8 0.0 1.5e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM04917.1 - 4.3e-14 52.1 0.1 1.8e-10 40.4 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain CN_hydrolase PF00795.17 CCM04918.1 - 1.8e-10 40.4 0.0 2.6e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 3Beta_HSD PF01073.14 CCM04919.1 - 1.4e-60 204.4 0.0 2e-57 194.0 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCM04919.1 - 9.4e-32 110.3 0.1 1.3e-31 109.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM04919.1 - 9.1e-16 58.3 0.0 1.5e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCM04919.1 - 3.5e-14 52.3 0.0 8e-10 38.0 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 CCM04919.1 - 4.3e-12 45.5 0.1 6.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CCM04919.1 - 4.8e-06 25.6 0.1 1.8e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CCM04919.1 - 0.014 15.3 0.2 0.058 13.3 0.2 2.2 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 CCM04919.1 - 0.077 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family KR PF08659.5 CCM04919.1 - 0.078 12.6 0.2 0.42 10.2 0.1 2.1 1 1 0 1 1 1 0 KR domain Mito_carr PF00153.22 CCM04921.1 - 6.6e-58 192.4 0.2 1.3e-23 82.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF898 PF05987.8 CCM04922.1 - 0.011 14.6 1.4 0.051 12.4 1.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) HAMP PF00672.20 CCM04922.1 - 0.21 11.8 1.1 0.46 10.6 0.7 1.6 1 0 0 1 1 1 0 HAMP domain Macoilin PF09726.4 CCM04922.1 - 4.4 5.4 7.8 5.3 5.1 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Carn_acyltransf PF00755.15 CCM04923.1 - 1.9e-165 551.3 0.0 2.4e-165 551.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sulfotransfer_3 PF13469.1 CCM04923.1 - 0.031 15.1 0.6 19 6.1 0.0 2.6 2 0 0 2 2 2 0 Sulfotransferase family DUF3818 PF12825.2 CCM04924.1 - 0.05 12.2 0.0 0.39 9.3 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function in PX-proteins (DUF3818) Linker_histone PF00538.14 CCM04925.1 - 1.5e-06 28.1 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family zf-CCCH PF00642.19 CCM04926.1 - 2.2e-23 81.4 23.1 6.9e-09 35.1 2.6 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCM04926.1 - 0.023 14.6 20.3 0.025 14.5 0.2 3.8 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Heme_oxygenase PF01126.15 CCM04927.1 - 5.7e-37 127.2 0.0 8.1e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase WD40 PF00400.27 CCM04928.1 - 0.014 15.2 0.6 2.7 7.9 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Asp PF00026.18 CCM04929.1 - 6.7e-47 160.2 17.5 1.2e-46 159.4 12.2 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM04929.1 - 6.6e-07 29.4 7.1 3.6e-06 27.0 3.6 2.9 1 1 2 3 3 3 1 Xylanase inhibitor N-terminal SelP_N PF04592.9 CCM04929.1 - 0.13 11.5 1.5 0.19 11.0 1.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Asp_protease_2 PF13650.1 CCM04929.1 - 0.14 12.7 10.5 0.098 13.1 1.1 3.3 3 0 0 3 3 3 0 Aspartyl protease F-box-like PF12937.2 CCM04930.1 - 0.0035 17.0 0.0 0.0091 15.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like BTB PF00651.26 CCM04931.1 - 9.9e-05 22.3 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_S8 PF00410.14 CCM04932.1 - 4.6e-27 94.4 0.1 6.5e-27 93.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 CCM04933.1 - 2.8e-45 153.0 0.0 3.5e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Aldo_ket_red PF00248.16 CCM04934.1 - 5.5e-51 173.0 0.0 7e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.26 CCM04935.1 - 0.00099 19.0 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ribonuc_red_lgC PF02867.10 CCM04937.1 - 2.8e-212 706.0 0.0 3.7e-212 705.6 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CCM04937.1 - 5.2e-21 74.2 0.0 1.4e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CCM04937.1 - 3.8e-07 30.4 0.2 1.4e-06 28.6 0.1 2.0 1 0 0 1 1 1 1 ATP cone domain Glyco_hydro_30 PF02055.11 CCM04938.1 - 2.4e-29 101.9 2.7 4.3e-29 101.0 1.9 1.3 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Pkinase PF00069.20 CCM04939.1 - 2.5e-07 30.0 0.0 0.016 14.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain FA_desaturase PF00487.19 CCM04940.1 - 6.9e-29 101.0 16.2 1.1e-28 100.4 11.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CCM04940.1 - 0.04 13.9 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Ribosomal_S19e PF01090.14 CCM04941.1 - 6.6e-56 187.6 0.0 7.6e-56 187.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e F-box-like PF12937.2 CCM04942.1 - 2.3e-10 40.0 2.4 7e-10 38.4 0.1 2.7 3 0 0 3 3 3 1 F-box-like A_deaminase PF00962.17 CCM04943.1 - 1.7e-108 362.4 0.8 2.1e-108 362.1 0.6 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase TPP_enzyme_N PF02776.13 CCM04944.1 - 4.1e-38 130.5 0.1 8e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCM04944.1 - 2.5e-23 82.3 0.0 6.2e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCM04944.1 - 1.3e-12 47.5 0.2 8.6e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1192 PF06698.6 CCM04944.1 - 0.09 12.5 0.3 0.29 10.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Peptidase_C97 PF05903.9 CCM04945.1 - 4.6e-32 110.8 0.0 8.7e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 CCM04945.1 - 3.3e-28 98.2 0.6 5.7e-28 97.4 0.4 1.4 1 1 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 CCM04945.1 - 1.4e-14 53.6 0.0 2.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCM04945.1 - 6.5e-05 23.1 0.1 0.00039 20.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 CCM04945.1 - 0.0026 17.3 0.0 0.018 14.5 0.0 2.2 2 1 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 CCM04945.1 - 0.028 14.4 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.1 CCM04945.1 - 0.065 13.3 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like DUF4284 PF14112.1 CCM04946.1 - 0.072 13.5 0.7 0.17 12.3 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) RFC1 PF08519.7 CCM04947.1 - 3.1e-51 173.2 0.0 2.2e-49 167.1 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 CCM04947.1 - 1.9e-13 50.3 0.0 5.7e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 CCM04947.1 - 3.2e-08 33.8 0.0 8.6e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCM04947.1 - 0.00046 19.0 0.1 0.0071 15.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCM04947.1 - 0.0013 18.8 0.0 0.0038 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCM04947.1 - 0.0018 18.1 0.0 0.0058 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCM04947.1 - 0.0019 17.8 0.1 0.0019 17.8 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CCM04947.1 - 0.0024 17.5 0.0 0.0068 16.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CCM04947.1 - 0.005 15.9 0.0 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CCM04947.1 - 0.0077 16.1 0.1 0.065 13.1 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CCM04947.1 - 0.011 15.7 0.1 0.043 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain FerA PF08165.6 CCM04947.1 - 0.023 14.3 0.8 1.6 8.4 0.1 2.6 2 0 0 2 2 2 0 FerA (NUC095) domain AAA_5 PF07728.9 CCM04947.1 - 0.042 13.5 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CCM04947.1 - 0.045 13.4 0.1 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 CCM04947.1 - 0.13 11.9 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CCM04947.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 CCM04947.1 - 0.15 12.8 0.1 0.15 12.8 0.0 2.5 3 0 0 3 3 1 0 AAA domain Asp PF00026.18 CCM04948.1 - 9.6e-75 251.7 0.3 1.1e-74 251.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCM04948.1 - 0.00034 21.0 0.1 1.7 9.1 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 CCM04948.1 - 0.00034 20.2 0.4 0.0038 16.7 0.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 CCM04948.1 - 0.0012 18.8 0.4 0.01 15.7 0.2 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal SH3_9 PF14604.1 CCM04949.1 - 2.4e-08 33.4 0.0 3.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCM04949.1 - 0.0031 16.8 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCM04949.1 - 0.049 13.1 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Tad PF13400.1 CCM04949.1 - 0.086 12.8 1.7 0.16 12.0 1.1 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF1634 PF07843.6 CCM04950.1 - 0.075 12.6 0.0 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) GMC_oxred_N PF00732.14 CCM04951.1 - 3.8e-63 213.3 0.0 6.4e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM04951.1 - 2.7e-34 118.5 0.0 5.6e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 CCM04951.1 - 2.6e-05 23.3 0.1 4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCM04951.1 - 0.0053 15.6 0.8 0.021 13.6 0.5 1.9 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CCM04951.1 - 0.0093 15.0 0.2 0.072 12.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 CCM04951.1 - 0.014 15.3 0.3 0.029 14.2 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gemini_AL1_M PF08283.6 CCM04951.1 - 0.14 12.0 0.2 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Geminivirus rep protein central domain HI0933_like PF03486.9 CCM04951.1 - 0.15 10.5 0.7 0.24 9.8 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Borrelia_P83 PF05262.6 CCM04952.1 - 0.0001 20.7 0.8 0.00013 20.3 0.6 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Rnk_N PF14760.1 CCM04952.1 - 0.026 14.5 2.4 0.026 14.5 1.7 2.0 2 0 0 2 2 2 0 Rnk N-terminus Cluap1 PF10234.4 CCM04952.1 - 0.027 13.6 1.5 0.039 13.1 1.1 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 EcoEI_R_C PF08463.5 CCM04952.1 - 0.028 14.2 7.3 0.17 11.7 0.9 2.3 2 1 0 2 2 2 0 EcoEI R protein C-terminal DivIC PF04977.10 CCM04952.1 - 0.066 12.7 3.5 0.088 12.3 1.3 2.0 1 1 1 2 2 2 0 Septum formation initiator AAA PF00004.24 CCM04953.1 - 2.1e-49 167.0 0.0 9.1e-42 142.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCM04953.1 - 2.6e-09 37.3 1.2 2.4e-06 27.6 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 CCM04953.1 - 3.5e-07 29.8 0.0 3.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 CCM04953.1 - 1.3e-06 28.5 0.1 0.0026 17.8 0.1 3.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM04953.1 - 1.1e-05 25.0 0.3 0.0037 16.9 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain AAA_2 PF07724.9 CCM04953.1 - 2e-05 24.6 0.0 4.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CCM04953.1 - 2.2e-05 24.3 0.0 0.011 15.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCM04953.1 - 0.00039 21.2 0.1 0.03 15.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 CCM04953.1 - 0.00069 19.3 0.0 0.017 14.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CCM04953.1 - 0.0027 17.6 0.0 0.067 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCM04953.1 - 0.0036 16.7 0.1 0.075 12.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain Torsin PF06309.6 CCM04953.1 - 0.0093 15.8 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 1 Torsin AAA_30 PF13604.1 CCM04953.1 - 0.018 14.6 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCM04953.1 - 0.018 15.3 1.4 0.039 14.2 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 CCM04953.1 - 0.019 14.9 0.0 0.085 12.8 0.0 2.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCM04953.1 - 0.021 15.0 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Sigma54_activ_2 PF14532.1 CCM04953.1 - 0.022 14.8 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 CCM04953.1 - 0.028 14.0 0.0 0.098 12.2 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CCM04953.1 - 0.034 14.4 0.0 0.27 11.5 0.0 2.5 3 0 0 3 3 2 0 ABC transporter Sigma54_activat PF00158.21 CCM04953.1 - 0.034 13.6 0.0 1.3 8.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.11 CCM04953.1 - 0.041 13.1 0.0 0.096 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.16 CCM04953.1 - 0.049 12.7 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CCM04953.1 - 0.054 13.1 0.2 0.46 10.1 0.0 2.6 2 1 0 2 2 2 0 NACHT domain TIP49 PF06068.8 CCM04953.1 - 0.072 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 CCM04953.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 CCM04953.1 - 0.12 11.1 0.0 0.51 9.1 0.0 2.0 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 PIF1 PF05970.9 CCM04953.1 - 0.44 9.4 0.0 0.76 8.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Glyco_hydro_85 PF03644.8 CCM04954.1 - 1.9e-74 250.6 0.0 2.7e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 RRM_1 PF00076.17 CCM04956.1 - 8.2e-27 92.6 0.3 2.8e-15 55.7 0.2 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM04956.1 - 1.3e-20 73.1 0.5 8e-10 38.5 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM04956.1 - 1e-07 31.7 0.4 0.0051 16.6 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 CCM04957.1 - 9.9e-69 232.1 0.0 2.6e-66 224.2 0.0 3.0 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CCM04957.1 - 0.0005 20.4 3.6 1.6 9.5 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat FTCD_C PF04961.7 CCM04957.1 - 0.004 16.5 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Formiminotransferase-cyclodeaminase TPR_16 PF13432.1 CCM04957.1 - 0.0046 17.5 4.5 0.1 13.2 0.6 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCM04957.1 - 0.16 12.4 1.2 8.4 7.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCM04957.1 - 0.2 12.0 9.1 15 5.9 0.1 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.1 CCM04957.1 - 0.26 10.3 7.8 0.4 9.7 0.1 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Cupin_2 PF07883.6 CCM04958.1 - 1.3e-19 69.4 0.1 4.4e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CCM04958.1 - 1e-16 60.6 0.1 1e-10 41.2 0.0 2.7 2 1 1 3 3 3 2 Cupin AraC_binding PF02311.14 CCM04958.1 - 2.8e-07 30.2 0.1 2.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.7 CCM04958.1 - 1.7e-05 24.1 0.0 0.00035 19.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 CCM04958.1 - 0.01 15.4 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 Cupin ARD PF03079.9 CCM04958.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.7 CCM04958.1 - 0.029 13.7 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Cupin_8 PF13621.1 CCM04958.1 - 0.031 13.7 0.0 0.079 12.4 0.0 1.8 1 1 0 1 1 1 0 Cupin-like domain DUF1971 PF09313.6 CCM04958.1 - 0.042 13.5 0.0 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) Cupin_4 PF08007.7 CCM04958.1 - 0.1 11.8 0.0 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein GPI PF06560.6 CCM04958.1 - 0.13 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.6 CCM04960.1 - 7.6e-29 99.0 0.9 6e-14 51.2 0.4 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CCM04960.1 - 4.1e-25 87.8 0.0 1.6e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 CCM04960.1 - 5.7e-09 35.2 0.2 0.00095 18.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 CCM04960.1 - 2.1e-05 24.1 0.0 0.00049 19.7 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 CCM04960.1 - 3.8e-05 23.3 1.0 0.0021 17.7 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_4 PF08007.7 CCM04960.1 - 0.01 15.1 0.1 0.084 12.1 0.0 2.0 2 0 0 2 2 2 0 Cupin superfamily protein FdtA PF05523.6 CCM04960.1 - 0.059 12.8 0.0 0.86 9.1 0.0 2.2 2 0 0 2 2 2 0 WxcM-like, C-terminal Pirin_C PF05726.8 CCM04960.1 - 0.071 13.1 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Pirin C-terminal cupin domain GPI PF06560.6 CCM04960.1 - 0.081 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) ARD PF03079.9 CCM04960.1 - 0.1 12.5 0.1 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family Mucin PF01456.12 CCM04960.1 - 0.17 11.6 14.5 0.41 10.4 10.0 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein SNO PF01174.14 CCM04961.1 - 2e-50 171.0 0.0 1.5e-48 164.9 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 CCM04961.1 - 3.4e-07 29.9 0.1 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.12 CCM04961.1 - 9e-05 22.2 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DUF4066 PF13278.1 CCM04961.1 - 0.007 15.6 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 CCM04961.1 - 0.014 14.8 0.1 0.054 12.9 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 CCM04961.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S10 PF00450.17 CCM04962.1 - 4e-78 263.4 0.0 5.5e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.17 CCM04963.1 - 2.4e-11 43.4 0.0 2.7e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase HisKA PF00512.20 CCM04966.1 - 4.5e-15 55.3 0.4 2.1e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.21 CCM04966.1 - 8.8e-15 54.3 0.1 1.9e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCM04966.1 - 1e-10 41.6 0.0 1.2e-09 38.1 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 CCM04966.1 - 2.7e-06 27.5 1.3 2.8e-05 24.2 0.0 2.9 3 1 0 3 3 3 1 GAF domain GAF_3 PF13492.1 CCM04966.1 - 2.7e-05 24.2 0.1 0.079 13.0 0.0 3.1 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 CCM04966.1 - 0.00012 22.5 0.0 1.6 9.2 0.0 3.7 3 0 0 3 3 3 2 GAF domain Rtt106 PF08512.7 CCM04966.1 - 0.19 11.7 0.0 0.59 10.1 0.0 1.8 1 0 0 1 1 1 0 Histone chaperone Rttp106-like Cys_Met_Meta_PP PF01053.15 CCM04967.1 - 6e-31 107.0 0.0 8e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 CCM04967.1 - 2.6e-20 72.2 0.0 1.4e-19 69.8 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCM04967.1 - 1.3e-05 25.3 2.2 5e-05 23.4 0.1 3.0 2 1 1 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 CCM04967.1 - 0.00045 19.4 0.0 0.0011 18.1 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Cys_Met_Meta_PP PF01053.15 CCM04968.1 - 3.3e-73 246.2 0.2 4.3e-73 245.8 0.2 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SelA PF03841.8 CCM04968.1 - 1.4e-05 24.0 0.0 0.00012 20.9 0.0 1.9 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Aminotran_1_2 PF00155.16 CCM04968.1 - 0.00016 20.8 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 CCM04968.1 - 0.0013 17.1 0.0 0.013 13.8 0.0 1.9 2 0 0 2 2 2 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 CCM04968.1 - 0.0023 17.1 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCM04968.1 - 0.011 14.7 0.2 0.019 14.0 0.1 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Wbp11 PF09429.5 CCM04969.1 - 0.15 12.1 3.0 0.31 11.0 0.2 2.2 2 1 0 2 2 2 0 WW domain binding protein 11 adh_short PF00106.20 CCM04970.1 - 1.9e-14 53.8 2.3 1.6e-12 47.6 1.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM04970.1 - 4.5e-07 29.6 0.9 8.7e-07 28.7 0.1 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CCM04970.1 - 7e-07 29.4 0.2 3.4e-05 23.9 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 CCM04970.1 - 1.2e-05 25.2 0.5 0.00035 20.4 0.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCM04970.1 - 0.0018 17.7 0.0 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CCM04970.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 CCM04970.1 - 0.0096 15.5 0.2 0.073 12.6 0.1 2.0 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 CCM04970.1 - 0.096 11.5 0.0 0.22 10.3 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Abhydrolase_1 PF00561.15 CCM04971.1 - 1.5e-35 122.8 0.0 2.3e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCM04971.1 - 3.7e-11 43.3 2.2 1.7e-10 41.1 1.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AATase PF07247.7 CCM04972.1 - 3.6e-39 134.6 0.0 4.6e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CCM04972.1 - 8.6e-12 44.5 0.2 3.3e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Condensation domain Transferase PF02458.10 CCM04972.1 - 0.049 12.0 0.0 0.069 11.5 0.0 1.2 1 0 0 1 1 1 0 Transferase family WES_acyltransf PF03007.11 CCM04972.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Terpene_synth_C PF03936.11 CCM04973.1 - 1.3e-14 54.1 0.5 2.1e-14 53.4 0.2 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain HMGL-like PF00682.14 CCM04974.1 - 7.3e-70 235.3 0.3 1.2e-69 234.5 0.2 1.4 1 0 0 1 1 1 1 HMGL-like Terpene_synth_C PF03936.11 CCM04975.1 - 1e-12 47.8 0.6 1.5e-12 47.3 0.4 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.14 CCM04976.1 - 3.1e-35 119.6 0.2 6e-35 118.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CCM04976.1 - 4.9e-30 103.7 0.6 8.6e-30 103.0 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 CCM04976.1 - 0.00073 19.3 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 Restriction endonuclease Penicillinase_R PF03965.11 CCM04976.1 - 0.12 12.5 0.1 0.66 10.0 0.0 2.2 3 0 0 3 3 3 0 Penicillinase repressor WD40 PF00400.27 CCM04977.1 - 1.8e-22 78.3 1.7 1.2e-06 28.1 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CCM04977.1 - 0.15 10.1 0.0 0.26 9.3 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Acetyltransf_3 PF13302.1 CCM04978.1 - 9.5e-13 48.5 0.0 1.2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCM04978.1 - 2.6e-05 24.1 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TRAP_alpha PF03896.11 CCM04979.1 - 2.4e-07 30.0 0.0 3.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit NDUFB10 PF10249.4 CCM04980.1 - 0.0041 17.2 0.7 0.0045 17.1 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 RAG2_PHD PF13341.1 CCM04980.1 - 0.052 13.5 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 RAG2 PHD domain ABC_tran_2 PF12848.2 CCM04980.1 - 0.26 11.1 2.1 0.29 11.0 1.1 1.4 1 1 0 1 1 1 0 ABC transporter Asp PF00026.18 CCM04981.1 - 4.5e-63 213.4 2.1 5.4e-63 213.1 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM04981.1 - 3.3e-05 23.8 0.7 0.00015 21.7 0.5 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Pkinase PF00069.20 CCM04982.1 - 3.5e-56 190.2 0.0 4.7e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM04982.1 - 4.3e-18 65.3 0.0 1.1e-17 64.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CCM04982.1 - 0.06 12.6 0.1 0.17 11.1 0.1 1.6 1 1 1 2 2 2 0 RIO1 family MOZ_SAS PF01853.13 CCM04983.1 - 1.9e-76 255.5 0.0 2.7e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 CCM04983.1 - 3.3e-19 68.3 21.1 4.4e-10 39.0 4.3 3.3 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 CCM04983.1 - 0.0041 16.4 12.8 0.027 13.8 1.2 3.4 3 0 0 3 3 3 2 PHD-finger DUF1295 PF06966.7 CCM04984.1 - 2.6e-42 144.7 0.1 3.3e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CCM04984.1 - 6e-06 26.3 0.1 1.3e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM04984.1 - 9.7e-05 22.4 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 CCM04984.1 - 0.0043 16.8 0.1 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Thioredoxin PF00085.15 CCM04985.1 - 0.00056 19.5 0.2 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 CCM04985.1 - 0.0015 18.0 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCM04985.1 - 0.0023 17.6 0.1 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 CCM04985.1 - 0.0035 17.4 0.1 0.0075 16.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Amidohydro_1 PF01979.15 CCM04988.1 - 6.9e-57 193.5 0.6 1.3e-56 192.6 0.4 1.5 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 CCM04988.1 - 2.6e-56 188.9 0.8 5e-56 188.0 0.5 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 CCM04988.1 - 7.2e-42 141.2 0.1 1.9e-41 139.9 0.0 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 CCM04988.1 - 2.7e-37 126.7 0.1 8.6e-37 125.1 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 CCM04988.1 - 0.00011 21.9 1.0 0.00029 20.5 0.7 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CCM04988.1 - 0.01 15.0 0.7 0.4 9.8 0.0 2.6 2 1 1 3 3 3 0 Amidohydrolase family EVC2_like PF12297.3 CCM04988.1 - 0.12 11.0 1.4 0.17 10.4 0.9 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein RNA_pol_Rpc82 PF05645.8 CCM04989.1 - 0.015 14.8 0.3 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 zf-NF-X1 PF01422.12 CCM04989.1 - 0.027 14.4 3.6 0.047 13.6 2.5 1.3 1 0 0 1 1 1 0 NF-X1 type zinc finger Acyl-CoA_dh_1 PF00441.19 CCM04990.1 - 3.7e-33 114.7 1.4 5.2e-33 114.2 1.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 CCM04990.1 - 6.7e-17 61.0 0.1 1.9e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 CCM04990.1 - 1.7e-13 49.8 0.7 4.7e-13 48.4 0.5 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CCM04990.1 - 5.6e-09 36.5 0.0 1.8e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCM04990.1 - 0.00011 22.4 0.9 0.00021 21.5 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RRM_6 PF14259.1 CCM04991.1 - 0.00012 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCM04991.1 - 0.00026 20.5 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPT2 PF08243.6 CCM04992.1 - 3.2e-14 53.2 12.6 3.2e-14 53.2 8.7 5.0 4 1 1 5 5 5 1 SPT2 chromatin protein MFS_1 PF07690.11 CCM04993.1 - 5.9e-35 120.6 55.7 6.7e-29 100.7 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.23 CCM04993.1 - 5.2e-11 42.3 5.8 1.6e-10 40.7 4.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCM04993.1 - 5.2e-07 29.6 0.0 2.2e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2945 PF11160.3 CCM04994.1 - 2.2e-05 24.2 0.1 0.026 14.3 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2945) Glyco_hydro_59 PF02057.10 CCM04994.1 - 0.12 10.4 0.0 0.13 10.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 TOM13 PF08219.6 CCM04995.1 - 1.7e-13 50.1 0.1 5.9e-13 48.3 0.0 2.0 1 0 0 1 1 1 1 Outer membrane protein TOM13 DUF3106 PF11304.3 CCM04995.1 - 0.029 14.7 6.1 0.069 13.5 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) MAP7 PF05672.6 CCM04995.1 - 0.2 11.0 18.3 0.5 9.7 12.8 1.7 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family FNIP_N PF14636.1 CCM04995.1 - 1.1 9.7 6.7 1.1 9.7 0.0 2.5 2 1 0 2 2 2 0 Folliculin-interacting protein N-terminus SPA PF08616.5 CCM04996.1 - 6.1e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CCM04996.1 - 0.033 12.6 0.0 0.048 12.1 0.0 1.2 1 0 0 1 1 1 0 Transport protein Avl9 Tcp11 PF05794.8 CCM05001.1 - 1e-13 50.8 0.0 1.6e-11 43.5 0.0 3.1 1 1 0 1 1 1 1 T-complex protein 11 Abhydrolase_6 PF12697.2 CCM05002.1 - 2.7e-10 40.5 0.0 3.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM05002.1 - 0.00013 21.7 0.0 0.00024 20.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 CCM05003.1 - 4.7e-64 216.6 0.0 6.9e-64 216.0 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Mg_trans_NIPA PF05653.9 CCM05004.1 - 6.7e-19 67.9 14.3 7e-10 38.3 1.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CCM05004.1 - 1.5e-05 25.1 3.6 1.5e-05 25.1 2.5 4.5 3 2 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CCM05004.1 - 0.00013 21.9 31.2 0.0035 17.3 6.1 3.7 3 1 0 3 3 3 2 EamA-like transporter family DUF788 PF05620.6 CCM05004.1 - 2.5 7.9 6.1 3.7 7.3 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF788) DUF262 PF03235.9 CCM05005.1 - 1.7e-08 34.7 0.1 5.4e-08 33.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF262 DUF2036 PF09724.4 CCM05006.1 - 1.8e-60 204.8 0.0 2.1e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Cation_efflux PF01545.16 CCM05007.1 - 6.8e-48 163.1 11.7 1.9e-45 155.1 8.1 2.4 1 1 0 1 1 1 1 Cation efflux family NicO PF03824.11 CCM05007.1 - 0.0094 15.2 2.1 0.0094 15.2 1.5 2.0 2 0 0 2 2 2 1 High-affinity nickel-transport protein Fe-ADH PF00465.14 CCM05008.1 - 6.2e-67 225.7 0.0 7.4e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CCM05008.1 - 2.5e-17 63.0 0.0 4.5e-17 62.1 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase ETF PF01012.16 CCM05008.1 - 0.07 12.8 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Electron transfer flavoprotein domain Fungal_trans PF04082.13 CCM05010.1 - 6.2e-24 84.2 0.0 1.9e-23 82.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Flavin_Reduct PF01613.13 CCM05012.1 - 2e-22 79.7 0.8 2.8e-22 79.2 0.6 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 CCM05012.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Sec7 PF01369.15 CCM05013.1 - 4.5e-20 72.1 0.0 6.9e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain FixG_C PF11614.3 CCM05013.1 - 0.02 15.0 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase CHCH PF06747.8 CCM05015.1 - 2.8e-07 30.2 3.4 5.5e-07 29.3 2.4 1.5 1 0 0 1 1 1 1 CHCH domain Lactamase_B PF00753.22 CCM05016.1 - 1.4e-07 31.3 0.2 2.4e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCM05016.1 - 7.3e-05 22.4 0.1 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain COPI_assoc PF08507.5 CCM05016.1 - 0.06 13.0 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 COPI associated protein E1-E2_ATPase PF00122.15 CCM05018.1 - 4.1e-29 101.2 0.0 8.1e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCM05018.1 - 2.6e-24 86.4 0.0 5.7e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCM05018.1 - 8e-22 78.7 0.0 3.2e-20 73.4 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 CCM05018.1 - 3.9e-20 71.8 0.1 8.7e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter V-SNARE_C PF12352.3 CCM05018.1 - 1.6e-16 60.0 0.1 3.7e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Cation_ATPase_C PF00689.16 CCM05018.1 - 7.4e-07 28.8 5.7 1.8e-06 27.6 3.9 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 CCM05018.1 - 0.00023 21.0 0.1 0.00079 19.3 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Sec20 PF03908.8 CCM05018.1 - 0.0032 17.1 0.0 0.0099 15.5 0.0 1.8 1 0 0 1 1 1 1 Sec20 Cation_ATPase_N PF00690.21 CCM05018.1 - 0.013 14.9 0.0 0.037 13.5 0.0 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCM05018.1 - 0.048 13.2 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Methyltransf_16 PF10294.4 CCM05019.1 - 3.4e-15 55.9 0.0 5.1e-14 52.0 0.0 2.5 1 1 0 1 1 1 1 Putative methyltransferase Nop25 PF09805.4 CCM05020.1 - 4.1e-21 75.4 19.8 4.1e-21 75.4 13.7 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF349 PF03993.7 CCM05020.1 - 0.012 15.7 1.2 0.012 15.7 0.8 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Ish1 PF10281.4 CCM05020.1 - 0.17 11.9 1.3 8.9 6.4 0.1 2.8 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein OPT PF03169.10 CCM05021.1 - 3.2e-200 666.7 60.6 3.7e-200 666.5 42.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Lactamase_B PF00753.22 CCM05022.1 - 9.3e-09 35.2 1.0 1.5e-08 34.4 0.7 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCM05022.1 - 7.6e-05 22.3 0.4 0.00011 21.7 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.9 CCM05023.1 - 1.4e-40 139.3 0.5 2.2e-40 138.7 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CCM05023.1 - 9.9e-31 106.0 0.0 1.8e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CCM05023.1 - 2.7e-20 72.5 5.0 6.3e-19 68.1 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM05023.1 - 1.7e-10 41.2 0.1 3.8e-07 30.3 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM05023.1 - 3.3e-08 32.4 1.8 0.0055 15.2 0.3 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 CCM05023.1 - 1.1e-07 31.2 0.2 2.6e-07 30.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 CCM05023.1 - 2.9e-06 26.4 0.0 4.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 CCM05023.1 - 0.0019 17.3 0.4 0.0045 16.1 0.1 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 CCM05023.1 - 0.005 15.7 2.1 0.005 15.7 1.5 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCM05023.1 - 0.0075 15.1 4.4 0.18 10.6 1.7 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 CCM05023.1 - 0.011 15.5 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CCM05023.1 - 0.016 15.1 1.2 0.052 13.5 0.8 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 CCM05023.1 - 0.064 12.8 0.1 0.064 12.8 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain APH PF01636.18 CCM05026.1 - 1.4e-08 34.8 1.2 3.8e-07 30.0 0.8 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM05026.1 - 0.0048 16.5 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 CCM05026.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Dynamin_M PF01031.15 CCM05028.1 - 1.3e-102 342.6 0.0 2.5e-102 341.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CCM05028.1 - 7.8e-55 185.2 0.0 1.4e-54 184.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CCM05028.1 - 1.8e-29 101.4 3.5 4.4e-29 100.2 2.4 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCM05028.1 - 0.00019 21.3 0.1 0.0024 17.8 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCM05028.1 - 0.027 14.9 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Glyco_hydro_88 PF07470.8 CCM05029.1 - 5.5e-14 51.9 0.7 6.6e-14 51.6 0.5 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 NTF2 PF02136.15 CCM05030.1 - 2.3e-32 111.8 0.0 2.6e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 CCM05030.1 - 0.0038 17.0 0.0 0.0043 16.8 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 TBP PF00352.16 CCM05033.1 - 1.9e-68 225.8 0.2 3.9e-34 115.8 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CCM05033.1 - 0.0058 16.6 5.6 1.1 9.3 0.0 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF3378) Gag_spuma PF03276.9 CCM05033.1 - 8 4.6 22.0 12 4.1 15.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein PAT1 PF09770.4 CCM05033.1 - 9.9 4.2 24.4 11 4.0 16.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Biotin_lipoyl PF00364.17 CCM05034.1 - 5.2e-20 70.8 0.1 1e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CCM05034.1 - 2.7e-08 33.2 0.1 8.1e-08 31.7 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CCM05034.1 - 0.0018 17.8 0.2 0.023 14.3 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like Pex14_N PF04695.8 CCM05034.1 - 3.2 7.7 7.8 0.25 11.3 1.4 2.0 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sterol-sensing PF12349.3 CCM05035.1 - 5.4e-37 126.5 8.9 5.4e-37 126.5 6.1 2.3 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CCM05035.1 - 2.9e-15 55.3 3.5 4.2e-15 54.7 2.5 1.1 1 0 0 1 1 1 1 Patched family ABM PF03992.11 CCM05036.1 - 0.00018 21.5 0.0 0.36 10.8 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Arginase PF00491.16 CCM05037.1 - 1.7e-81 273.5 0.1 2.1e-81 273.2 0.1 1.0 1 0 0 1 1 1 1 Arginase family DUF3535 PF12054.3 CCM05038.1 - 2.5e-95 319.7 3.2 3.5e-95 319.2 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CCM05038.1 - 1.5e-76 257.0 0.0 2.2e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 CCM05038.1 - 9.8e-14 50.1 17.6 1.2 9.3 0.0 9.9 10 0 0 10 10 10 5 HEAT repeat Helicase_C PF00271.26 CCM05038.1 - 7.3e-13 48.1 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 CCM05038.1 - 7.9e-06 26.2 17.2 15 6.1 0.0 9.6 9 1 2 11 11 11 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCM05038.1 - 0.00094 19.5 0.0 1.7 9.1 0.0 2.9 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CCM05038.1 - 0.0019 17.6 0.0 0.0097 15.2 0.0 2.2 2 0 0 2 2 2 1 CLASP N terminal DUF1546 PF07571.8 CCM05038.1 - 0.019 15.0 0.7 1.1 9.3 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1546) DUF3385 PF11865.3 CCM05038.1 - 0.098 12.5 0.0 0.95 9.3 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) Cupin_8 PF13621.1 CCM05039.1 - 2.5e-36 125.4 0.1 3.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CCM05039.1 - 1.4e-06 27.7 0.0 4.1e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.6 CCM05039.1 - 0.0011 18.4 0.0 0.003 17.0 0.0 1.7 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.17 CCM05039.1 - 0.0016 18.6 0.0 0.01 16.0 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_3 PF05899.7 CCM05039.1 - 0.041 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 CCM05039.1 - 0.051 13.2 0.2 0.19 11.3 0.0 2.0 3 0 0 3 3 3 0 AraC-like ligand binding domain RabGAP-TBC PF00566.13 CCM05040.1 - 6.5e-29 100.9 0.1 3.8e-28 98.4 0.1 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain FAD_binding_2 PF00890.19 CCM05041.1 - 5.5e-126 420.7 3.3 7e-126 420.4 2.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CCM05041.1 - 1.2e-47 160.9 0.3 1.8e-47 160.3 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 CCM05041.1 - 2.2e-07 30.9 0.2 6.2e-05 22.9 0.2 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM05041.1 - 2.4e-06 26.8 0.1 0.0082 15.2 0.0 3.0 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 CCM05041.1 - 8.2e-06 24.9 1.9 0.008 15.0 1.5 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 CCM05041.1 - 2.7e-05 23.2 0.6 0.00084 18.3 0.4 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCM05041.1 - 0.0038 16.3 0.1 0.0064 15.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CCM05041.1 - 0.081 12.9 0.2 1 9.3 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transaldolase PF00923.14 CCM05041.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Transaldolase HI0933_like PF03486.9 CCM05041.1 - 0.13 10.6 2.7 0.33 9.3 0.6 2.5 3 1 0 3 3 3 0 HI0933-like protein G-patch PF01585.18 CCM05042.1 - 8e-07 28.7 3.3 2.5e-06 27.1 2.3 1.9 1 0 0 1 1 1 1 G-patch domain p450 PF00067.17 CCM05043.1 - 6.7e-68 229.2 0.0 7.9e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cullin_binding PF03556.10 CCM05044.1 - 5.6e-27 94.2 1.6 8.5e-27 93.6 1.1 1.2 1 0 0 1 1 1 1 Cullin binding DUF59 PF01883.14 CCM05046.1 - 8.5e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 UCH_1 PF13423.1 CCM05048.1 - 5e-50 170.6 0.1 7.4e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CCM05048.1 - 8.9e-25 87.8 0.0 1.8e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 CCM05048.1 - 1.2e-10 41.0 0.0 2.3e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 CCM05048.1 - 0.001 18.8 1.2 0.2 11.6 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Sas10_Utp3 PF04000.10 CCM05049.1 - 9e-09 35.4 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family HisKA_3 PF07730.8 CCM05049.1 - 0.013 15.7 0.6 0.048 14.0 0.1 2.3 2 0 0 2 2 2 0 Histidine kinase Abhydrolase_6 PF12697.2 CCM05050.1 - 4.6e-22 79.0 0.0 6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM05050.1 - 3.1e-17 62.9 0.0 5.9e-16 58.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM05050.1 - 1.3e-05 24.9 0.0 5.4e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CCM05050.1 - 0.00033 20.1 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S10 PF00450.17 CCM05050.1 - 0.012 14.7 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Serine carboxypeptidase Copper-bind PF00127.15 CCM05051.1 - 0.0026 17.9 1.9 2.4 8.4 0.0 2.9 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 CCM05051.1 - 0.0032 17.3 0.1 0.51 10.2 0.0 2.9 3 0 0 3 3 3 1 Cupredoxin-like domain Cu_bind_like PF02298.12 CCM05051.1 - 0.047 13.4 0.7 22 4.9 0.2 3.4 2 1 0 2 2 2 0 Plastocyanin-like domain dsDNA_bind PF01984.15 CCM05052.1 - 1.8e-26 92.1 9.4 2.1e-26 92.0 6.5 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PCI PF01399.22 CCM05052.1 - 0.033 14.5 0.1 0.045 14.0 0.1 1.3 1 0 0 1 1 1 0 PCI domain zf-RING_4 PF14570.1 CCM05053.1 - 4.3e-22 77.4 11.7 7e-22 76.7 8.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CCM05053.1 - 1.7e-05 24.3 7.9 3.3e-05 23.4 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 CCM05053.1 - 0.00011 21.8 0.0 0.00035 20.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM05053.1 - 0.00055 19.7 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CCM05053.1 - 0.0027 17.7 12.5 0.0046 16.9 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CCM05053.1 - 0.033 13.9 3.2 0.077 12.7 2.2 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 CCM05053.1 - 0.046 13.4 3.7 0.087 12.5 2.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 CCM05053.1 - 0.11 12.1 11.8 0.19 11.3 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PsbQ PF05757.6 CCM05055.1 - 0.055 12.8 0.0 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) zf-RING_2 PF13639.1 CCM05056.1 - 1.5e-09 37.5 17.9 4.9e-08 32.6 8.2 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 CCM05056.1 - 1e-07 31.4 13.2 1e-07 31.4 9.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM05056.1 - 2.2e-07 30.5 17.2 7.9e-07 28.7 8.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCM05056.1 - 5e-07 29.2 16.3 6.8e-07 28.8 7.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCM05056.1 - 1.8e-06 27.8 13.1 1.8e-06 27.8 9.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM05056.1 - 3.8e-06 26.6 13.3 3.8e-06 26.6 9.2 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCM05056.1 - 5.8e-06 25.9 5.5 2e-05 24.2 3.8 2.0 1 1 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 CCM05056.1 - 3.4e-05 23.7 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.1 CCM05056.1 - 3.8e-05 23.3 4.5 3.8e-05 23.3 3.1 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein PRP21_like_P PF12230.3 CCM05056.1 - 0.016 14.7 1.6 0.18 11.3 0.1 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein hDGE_amylase PF14701.1 CCM05056.1 - 0.045 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF1796 PF08795.5 CCM05056.1 - 0.079 12.5 0.3 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) zf-rbx1 PF12678.2 CCM05056.1 - 0.079 13.0 11.8 0.049 13.7 5.5 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CCM05056.1 - 0.42 10.2 16.1 0.093 12.3 5.1 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain NIF PF03031.13 CCM05057.1 - 5.5e-50 169.1 0.0 8.1e-50 168.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mitofilin PF09731.4 CCM05057.1 - 1.4 7.4 5.9 2 7.0 4.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Med4 PF10018.4 CCM05058.1 - 0.0032 16.8 1.4 0.0056 16.0 1.0 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 KTI12 PF08433.5 CCM05059.1 - 2.8e-20 72.6 0.0 3.3e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 O-FucT PF10250.4 CCM05060.1 - 6.4e-05 22.2 0.0 9.7e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase BTB PF00651.26 CCM05061.1 - 1.8e-11 43.9 0.0 3.7e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain RhoGAP PF00620.22 CCM05062.1 - 3e-41 140.5 0.1 1.9e-40 137.9 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CCM05062.1 - 4.8e-16 58.5 17.2 6.6e-08 32.5 5.8 2.4 2 0 0 2 2 2 2 LIM domain DUF2603 PF10788.4 CCM05062.1 - 0.18 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) DUF2685 PF10886.3 CCM05062.1 - 0.62 10.1 4.8 23 5.0 0.6 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2685) COesterase PF00135.23 CCM05063.1 - 2.1e-95 320.4 0.0 3.1e-95 319.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM05063.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM05063.1 - 0.029 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family adh_short PF00106.20 CCM05064.1 - 3e-18 66.2 0.0 4.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM05064.1 - 1.7e-11 44.3 0.0 2.1e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM05064.1 - 3.1e-05 23.7 0.0 6.9e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CCM05064.1 - 6.4e-05 23.0 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM05064.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCM05064.1 - 0.0066 15.4 0.0 0.16 10.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCM05065.1 - 5.6e-17 62.1 0.3 7.6e-17 61.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM05065.1 - 6.6e-14 52.2 0.0 8.6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM05065.1 - 3.1e-05 23.7 0.0 7.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCM05065.1 - 5.2e-05 23.3 0.1 0.00017 21.6 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM05065.1 - 0.0028 17.1 0.0 0.0055 16.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CCM05065.1 - 0.0059 15.7 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 CCM05065.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Amidase PF01425.16 CCM05066.1 - 4e-99 332.4 0.0 5e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF3439 PF11921.3 CCM05066.1 - 0.046 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NIF PF03031.13 CCM05067.1 - 1.5e-53 180.6 0.3 2.4e-53 180.0 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTPLA PF04387.9 CCM05068.1 - 3.1e-50 169.8 11.4 6.9e-50 168.6 7.9 1.6 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA bZIP_1 PF00170.16 CCM05068.1 - 1.7e-05 24.6 6.8 1.7e-05 24.6 4.7 2.1 2 0 0 2 2 2 1 bZIP transcription factor Asp PF00026.18 CCM05069.1 - 7.1e-55 186.4 0.5 9.8e-55 186.0 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM05069.1 - 1.1e-05 25.4 4.5 2.5e-05 24.2 1.9 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal adh_short_C2 PF13561.1 CCM05070.1 - 5.2e-15 55.8 0.0 6.4e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCM05070.1 - 1.6e-14 54.2 0.0 2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM05070.1 - 0.00073 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_hydro_16 PF00722.16 CCM05071.1 - 0.0001 21.6 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PPR_2 PF13041.1 CCM05072.1 - 5.5e-33 112.7 0.3 9e-05 22.3 0.0 8.7 5 4 4 9 9 9 8 PPR repeat family PPR_3 PF13812.1 CCM05072.1 - 4.6e-23 79.5 9.0 0.00095 19.2 0.0 10.2 12 0 0 12 12 12 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCM05072.1 - 2e-10 39.9 0.6 0.45 10.0 0.0 6.1 6 0 0 6 6 6 4 PPR repeat PPR PF01535.15 CCM05072.1 - 2.4e-10 39.6 2.3 3.4 7.8 0.0 8.4 10 0 0 10 10 10 4 PPR repeat ECSIT PF06239.6 CCM05072.1 - 0.0099 14.7 0.4 11 4.8 0.1 3.8 2 1 1 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway GMP_synt_C PF00958.17 CCM05072.1 - 0.046 13.4 0.0 14 5.4 0.0 3.4 2 1 0 2 2 2 0 GMP synthase C terminal domain Rad21_Rec8_N PF04825.8 CCM05073.1 - 1.1e-29 102.6 0.4 2.4e-29 101.4 0.3 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CCM05073.1 - 4.7e-09 35.3 0.0 9.8e-09 34.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF4201 PF13870.1 CCM05073.1 - 0.2 11.0 28.3 0.39 10.1 9.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) PALP PF00291.20 CCM05074.1 - 7.5e-64 215.8 0.1 8.6e-64 215.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.16 CCM05075.1 - 7.8e-77 256.4 0.0 1e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCM05075.1 - 9.7e-13 47.8 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCM05075.1 - 2.3e-11 43.2 0.0 4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCM05075.1 - 5.3e-11 41.8 1.3 2.5e-07 29.7 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCM05075.1 - 1.8e-09 37.0 0.0 2.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCM05075.1 - 7.2e-07 29.7 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCM05075.1 - 0.00051 19.9 0.1 0.0013 18.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CCM05075.1 - 0.032 13.2 0.1 0.053 12.5 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase L27 PF02828.11 CCM05075.1 - 0.078 12.6 1.2 0.34 10.6 0.1 2.4 3 0 0 3 3 3 0 L27 domain LRR_4 PF12799.2 CCM05076.1 - 5.4e-16 57.8 17.4 3.2e-06 26.6 1.1 5.9 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM05076.1 - 2.7e-14 52.6 14.1 6e-10 38.7 3.8 4.6 4 1 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 CCM05076.1 - 5e-08 31.9 16.6 0.15 12.2 0.5 7.4 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 CCM05076.1 - 0.0035 17.2 12.7 8 7.1 0.3 5.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CCM05076.1 - 0.063 13.3 17.0 1.1 9.5 0.3 5.4 6 1 0 6 6 6 0 Leucine Rich repeat ubiquitin PF00240.18 CCM05077.1 - 1.5e-20 72.3 2.3 2.2e-20 71.8 1.6 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CCM05077.1 - 1.5e-13 50.1 0.2 2.3e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 CCM05077.1 - 5.2e-09 35.6 2.5 8.3e-09 35.0 1.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CCM05077.1 - 2.2e-05 24.2 0.1 5.4e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCM05077.1 - 4.8e-05 23.4 0.6 9.1e-05 22.5 0.1 1.6 1 1 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 CCM05077.1 - 0.0093 16.2 0.4 0.015 15.5 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain UBA_3 PF09288.5 CCM05077.1 - 0.049 13.2 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain CUE PF02845.11 CCM05077.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 CUE domain DEC-1_N PF04625.8 CCM05077.1 - 0.21 10.2 15.2 0.31 9.6 10.6 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FAP PF07174.6 CCM05077.1 - 6.6 5.9 25.8 10 5.2 17.9 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) p450 PF00067.17 CCM05078.1 - 4.9e-43 147.3 0.0 1.7e-23 82.8 0.0 3.1 1 1 1 2 2 2 2 Cytochrome P450 Thioredox_DsbH PF03190.10 CCM05079.1 - 6e-68 227.6 0.0 1e-67 226.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 CCM05079.1 - 3.9e-11 42.8 0.0 1.5e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CCM05079.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain A_deaminase PF00962.17 CCM05080.1 - 7.2e-47 159.9 0.0 1.6e-46 158.7 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 CCM05080.1 - 0.0016 18.3 0.2 0.026 14.5 0.1 2.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Macro_2 PF14519.1 CCM05081.1 - 9.8e-06 24.8 0.0 0.044 12.9 0.0 2.2 2 0 0 2 2 2 2 Macro-like domain Macro PF01661.16 CCM05081.1 - 0.0046 16.8 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 Macro domain Methyltransf_25 PF13649.1 CCM05081.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase_Tyr PF07714.12 CCM05082.1 - 1.2e-43 149.1 0.0 1.8e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM05082.1 - 4.2e-40 137.5 0.0 7.1e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CCM05082.1 - 0.0072 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCM05082.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM05082.1 - 0.17 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FAD_binding_4 PF01565.18 CCM05083.1 - 8.7e-14 51.1 0.1 1.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CCM05083.1 - 1.9e-09 37.3 0.4 4.2e-09 36.1 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Macro_2 PF14519.1 CCM05084.1 - 8e-05 21.8 0.1 0.01 14.9 0.1 2.5 2 1 0 2 2 2 2 Macro-like domain Methyltransf_25 PF13649.1 CCM05084.1 - 0.089 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 CCM05085.1 - 0.014 14.0 0.1 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DUF647 PF04884.9 CCM05086.1 - 8.4e-72 241.3 3.8 1.2e-70 237.5 2.6 2.1 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cu-oxidase PF00394.17 CCM05087.1 - 1.5e-42 145.1 0.0 1.4e-36 125.8 0.1 3.5 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCM05087.1 - 2.5e-34 117.5 7.0 2.1e-32 111.2 0.3 3.9 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCM05087.1 - 8.2e-34 116.0 3.9 6.1e-33 113.2 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase FTR1 PF03239.9 CCM05088.1 - 9.7e-65 218.5 3.7 1.1e-64 218.2 2.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family ETRAMP PF09716.5 CCM05088.1 - 0.3 11.0 2.2 7.5 6.5 0.0 2.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) p450 PF00067.17 CCM05089.1 - 3.5e-54 184.0 0.0 4.7e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_28 PF13521.1 CCM05089.1 - 0.015 15.2 0.7 0.041 13.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain Ndr PF03096.9 CCM05089.1 - 0.17 10.3 0.0 0.32 9.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family zf-C2H2_4 PF13894.1 CCM05090.1 - 2.3e-05 24.3 0.3 0.011 15.9 0.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_3 PF14369.1 CCM05090.1 - 0.12 12.3 3.4 0.72 9.9 0.1 2.4 2 0 0 2 2 2 0 zinc-finger zf-Di19 PF05605.7 CCM05090.1 - 0.39 10.8 5.2 0.62 10.2 0.7 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding p450 PF00067.17 CCM05091.1 - 9.2e-44 149.7 0.0 1.3e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AT_hook PF02178.14 CCM05092.1 - 0.9 9.4 10.5 0.054 13.1 1.9 3.3 2 0 0 2 2 2 0 AT hook motif Methyltransf_16 PF10294.4 CCM05093.1 - 2.9e-05 23.5 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 CCM05093.1 - 0.0065 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM05093.1 - 0.14 11.7 0.0 6.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain F-box-like PF12937.2 CCM05094.1 - 0.0021 17.7 1.2 0.0059 16.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like DUF4336 PF14234.1 CCM05095.1 - 2.1e-15 56.6 0.0 3.4e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) ChAPs PF09295.5 CCM05097.1 - 5.2e-147 489.7 0.0 9.4e-146 485.6 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 CCM05097.1 - 1.7e-09 37.8 2.2 3.5e-06 27.2 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CCM05097.1 - 1.9e-08 34.3 2.8 0.0096 16.0 0.1 3.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CCM05097.1 - 4e-05 23.1 3.5 0.0036 16.9 0.1 3.8 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.1 CCM05097.1 - 6.8e-05 23.1 3.5 12 6.8 0.0 6.6 5 1 3 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCM05097.1 - 0.00036 20.2 5.6 0.73 9.9 0.0 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCM05097.1 - 0.0022 17.8 5.6 0.81 9.6 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.3 CCM05097.1 - 0.0034 16.1 0.7 0.018 13.8 0.0 2.0 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 CCM05097.1 - 0.0042 16.1 4.9 0.75 8.7 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCM05097.1 - 0.0059 16.3 0.2 4.5 7.2 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCM05097.1 - 0.019 15.5 0.5 7.6 7.3 0.0 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat Sugar_tr PF00083.19 CCM05098.1 - 7.4e-41 140.1 24.0 3.8e-39 134.5 16.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM05098.1 - 1.9e-17 63.0 37.0 3.2e-10 39.2 11.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCM05098.1 - 0.00032 19.2 21.4 0.031 12.6 3.0 3.4 2 1 1 3 3 3 3 MFS/sugar transport protein DUF606 PF04657.8 CCM05098.1 - 0.39 10.7 22.3 0.15 12.1 1.9 4.1 4 0 0 4 4 4 0 Protein of unknown function, DUF606 BT1 PF03092.11 CCM05098.1 - 2.5 6.7 10.2 21 3.6 7.1 2.2 1 1 0 1 1 1 0 BT1 family G-alpha PF00503.15 CCM05099.1 - 1.9e-75 253.9 0.0 2.4e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 CCM05099.1 - 0.0018 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CCM05099.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DAP3 PF10236.4 CCM05099.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AA_kinase PF00696.23 CCM05100.1 - 7.8e-40 136.9 0.0 1e-38 133.3 0.0 2.2 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 CCM05100.1 - 2.3e-12 46.1 0.7 2.1e-06 27.1 0.0 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 CCM05100.1 - 1.8e-08 33.8 0.7 3.4e-06 26.4 0.1 2.6 2 0 0 2 2 2 2 ACT domain Sugar_tr PF00083.19 CCM05101.1 - 1.5e-36 125.9 29.0 6.4e-36 123.9 20.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM05101.1 - 5e-16 58.3 39.2 1.2e-09 37.3 13.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily VirB3 PF05101.8 CCM05101.1 - 0.024 14.5 1.1 0.1 12.6 0.7 2.1 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein TRI12 PF06609.8 CCM05101.1 - 0.027 12.6 5.9 0.013 13.7 1.4 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 CCM05101.1 - 0.036 12.7 5.8 0.71 8.5 4.0 2.2 1 1 0 1 1 1 0 BT1 family DUF606 PF04657.8 CCM05101.1 - 8.7 6.4 27.2 0.045 13.8 2.6 4.3 4 1 0 4 4 4 0 Protein of unknown function, DUF606 DUF4387 PF14330.1 CCM05102.1 - 6.6e-35 119.4 0.0 1.3e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 CCM05102.1 - 5.1e-17 61.3 0.0 1.8e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1446) MFS_1 PF07690.11 CCM05103.1 - 2.2e-20 72.7 75.4 9.2e-17 60.7 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCM05103.1 - 0.00057 18.4 22.6 0.0019 16.6 15.0 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein adh_short PF00106.20 CCM05104.1 - 2.1e-32 112.3 0.4 2.6e-32 112.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM05104.1 - 3.4e-24 85.9 0.0 4.5e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM05104.1 - 2.7e-10 40.1 0.3 4.3e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCM05104.1 - 0.085 12.8 0.5 0.17 11.8 0.3 1.6 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 CCM05104.1 - 0.11 12.1 0.2 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CCM05104.1 - 0.12 11.0 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCM05105.1 - 4.3e-25 88.5 1.7 8.1e-25 87.6 1.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM05105.1 - 8.4e-11 41.8 1.0 1.6e-10 40.9 0.6 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM05105.1 - 1.1e-07 31.9 0.0 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCM05106.1 - 1.7e-31 109.4 4.7 2.1e-31 109.1 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM05106.1 - 1.1e-18 67.8 0.7 2e-18 67.0 0.5 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM05106.1 - 7.7e-09 35.4 3.0 1.2e-08 34.8 2.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CCM05106.1 - 0.11 12.1 1.0 0.19 11.3 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0254 PF06787.6 CCM05106.1 - 0.18 11.3 6.7 0.072 12.6 0.6 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0254) C1_1 PF00130.17 CCM05109.1 - 0.018 14.7 0.7 0.038 13.7 0.5 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CENP-B_dimeris PF09026.5 CCM05109.1 - 0.051 13.8 2.3 1 9.6 0.3 3.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-RING_2 PF13639.1 CCM05109.1 - 0.11 12.3 1.1 0.27 11.0 0.8 1.6 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 CCM05109.1 - 0.29 11.1 1.2 0.66 9.9 0.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Nucleoplasmin PF03066.10 CCM05109.1 - 5 6.6 5.8 1.8 8.0 0.7 2.2 2 0 0 2 2 2 0 Nucleoplasmin NARP1 PF12569.3 CCM05111.1 - 9e-173 575.7 3.6 8.7e-172 572.4 1.2 2.4 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CCM05111.1 - 4.3e-15 55.1 5.8 0.005 16.4 0.0 6.8 6 1 1 7 7 6 3 TPR repeat TPR_16 PF13432.1 CCM05111.1 - 5.4e-14 52.4 17.5 0.0065 17.1 0.3 9.1 8 2 1 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCM05111.1 - 2.7e-12 45.6 7.1 0.0083 15.9 0.0 8.4 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCM05111.1 - 3.4e-09 36.5 15.5 1.1 10.1 0.1 10.8 9 3 4 13 13 11 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCM05111.1 - 6.7e-09 35.9 22.7 0.016 15.5 0.1 8.7 6 3 2 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCM05111.1 - 4.9e-08 32.2 6.3 0.0048 16.4 0.2 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM05111.1 - 3e-07 30.2 9.8 0.24 11.3 0.3 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 CCM05111.1 - 2.1e-06 27.7 3.3 0.003 17.6 0.2 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCM05111.1 - 0.00065 19.3 0.6 1.6 8.6 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCM05111.1 - 0.0011 19.0 0.0 54 4.3 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 CCM05111.1 - 0.021 15.2 4.7 1.7 9.3 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCM05111.1 - 0.027 14.3 5.2 13 5.7 0.0 5.1 5 1 1 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.12 CCM05111.1 - 0.08 13.2 3.8 0.17 12.2 0.4 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain MIT PF04212.13 CCM05111.1 - 0.091 12.6 3.3 0.16 11.8 0.0 3.2 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 CCM05111.1 - 0.45 10.4 0.1 0.45 10.4 0.0 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCM05111.1 - 2.6 8.6 13.7 96 3.7 0.0 7.5 9 0 0 9 9 7 0 Tetratricopeptide repeat CLASP_N PF12348.3 CCM05112.1 - 9.9e-05 21.7 3.9 0.094 12.0 0.0 4.5 3 3 2 5 5 5 2 CLASP N terminal HEAT_2 PF13646.1 CCM05112.1 - 0.00052 20.2 8.3 0.034 14.4 0.1 4.6 2 2 1 3 3 3 1 HEAT repeats HEAT PF02985.17 CCM05112.1 - 0.0058 16.6 2.3 2 8.6 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat DUF1416 PF07210.7 CCM05112.1 - 0.021 14.4 0.0 0.07 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Ribosomal_L44 PF00935.14 CCM05113.1 - 3.4e-33 113.4 10.2 3.4e-33 113.4 7.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L44 DUF2277 PF10041.4 CCM05113.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) Pkinase PF00069.20 CCM05114.1 - 1e-66 224.7 0.0 1.3e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05114.1 - 4.3e-31 107.9 0.0 6.5e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PLA2_B PF01735.13 CCM05117.1 - 4.8e-100 335.0 0.0 5.7e-100 334.8 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 CCM05118.1 - 3.4e-96 322.3 0.0 4.3e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Aminotran_1_2 PF00155.16 CCM05119.1 - 4.6e-36 124.5 0.0 2.7e-34 118.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CCM05119.1 - 9.1e-06 24.1 0.0 1.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCM05119.1 - 2.2e-05 23.7 0.1 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CCM05119.1 - 0.00043 19.5 0.0 0.00065 18.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCM05119.1 - 0.036 12.8 0.0 0.06 12.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V DUF836 PF05768.9 CCM05120.1 - 2.7e-13 50.0 0.0 4.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 CCM05120.1 - 0.0034 17.1 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain zf-CCHC PF00098.18 CCM05120.1 - 0.036 13.9 0.4 0.061 13.2 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCM05120.1 - 0.051 13.2 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF2975 PF11188.3 CCM05121.1 - 0.52 10.0 8.4 9.4 5.9 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) COPI_assoc PF08507.5 CCM05121.1 - 3 7.5 10.3 8.9 5.9 7.0 1.8 1 1 0 1 1 1 0 COPI associated protein MFS_1 PF07690.11 CCM05122.1 - 2.6e-36 125.0 31.6 2.6e-36 125.0 21.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM05122.1 - 9.1e-18 64.0 29.2 1.3e-17 63.5 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 CCM05122.1 - 0.29 9.1 8.8 37 2.1 6.1 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RNase_H PF00075.19 CCM05124.1 - 1e-25 90.5 0.0 3.8e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.11 CCM05124.1 - 4.7e-17 61.7 0.2 8.9e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin adh_short PF00106.20 CCM05125.1 - 9.2e-28 97.2 4.8 1.2e-27 96.8 3.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM05125.1 - 3.2e-21 76.2 0.1 3.9e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM05125.1 - 2.7e-11 43.4 1.9 4.2e-11 42.8 1.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM05125.1 - 0.0046 16.4 0.1 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CCM05125.1 - 0.012 15.2 0.2 0.11 12.1 0.3 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HTH_Tnp_IS1 PF12759.2 CCM05125.1 - 0.031 13.7 0.2 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 InsA C-terminal domain F420_oxidored PF03807.12 CCM05125.1 - 0.14 12.5 1.1 0.32 11.4 0.2 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 CCM05125.1 - 0.17 11.8 1.4 0.34 10.9 1.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding APH PF01636.18 CCM05127.1 - 8.3e-06 25.7 0.0 5.6e-05 22.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM05127.1 - 1.9e-05 24.3 0.1 0.0016 18.0 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase RIO1 PF01163.17 CCM05127.1 - 0.00014 21.3 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CCM05127.1 - 0.0021 17.1 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CCM05127.1 - 0.0055 15.9 0.0 0.0076 15.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain EcKinase PF02958.15 CCM05127.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase AP_endonuc_2 PF01261.19 CCM05128.1 - 6.1e-27 94.3 0.1 1e-26 93.5 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Caerin_1 PF07440.7 CCM05128.1 - 0.13 12.1 0.2 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Caerin 1 protein Clathrin PF00637.15 CCM05130.1 - 2.6e-16 59.5 0.1 7.8e-14 51.4 0.2 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 CCM05130.1 - 0.00038 20.2 0.1 0.001 18.9 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 CCM05130.1 - 0.0029 17.3 8.2 0.0029 17.3 5.7 2.0 2 0 0 2 2 2 1 Ring finger domain Vps39_1 PF10366.4 CCM05130.1 - 0.005 16.8 0.1 0.034 14.1 0.0 2.5 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Hamartin PF04388.7 CCM05130.1 - 0.048 12.3 0.2 0.064 11.9 0.2 1.2 1 0 0 1 1 1 0 Hamartin protein zf-RING_5 PF14634.1 CCM05130.1 - 0.099 12.3 7.8 0.17 11.6 5.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCM05130.1 - 0.23 11.4 9.7 0.077 13.0 4.8 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCM05130.1 - 5.2 6.8 7.5 9.6 5.9 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCM05130.1 - 5.8 7.1 7.2 13 5.9 5.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger ParA PF10609.4 CCM05131.1 - 1.5e-30 104.9 0.1 2.6e-30 104.1 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCM05131.1 - 1.3e-15 57.3 0.0 2.4e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CCM05131.1 - 2.9e-08 33.7 0.1 1.2e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 CCM05131.1 - 0.00031 19.8 1.3 0.012 14.7 1.3 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 CCM05131.1 - 0.00092 18.3 0.2 0.0016 17.5 0.0 1.4 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.1 CCM05131.1 - 0.0045 16.4 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CCM05131.1 - 0.048 12.8 0.3 0.1 11.7 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NAD_binding_10 PF13460.1 CCM05132.1 - 9.3e-06 25.7 0.0 0.26 11.2 0.0 3.0 2 1 0 2 2 2 2 NADH(P)-binding Abhydrolase_6 PF12697.2 CCM05133.1 - 4.1e-11 43.1 0.9 8.3e-11 42.2 0.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM05133.1 - 0.00087 19.0 0.0 0.0019 17.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM05133.1 - 0.0053 16.3 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CCM05133.1 - 0.0064 16.1 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 CCM05133.1 - 0.16 11.5 0.5 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.20 CCM05133.1 - 0.16 11.5 0.0 5 6.7 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) zf-C2H2 PF00096.21 CCM05134.1 - 2.9e-05 24.1 1.1 0.2 12.0 0.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCM05134.1 - 0.00012 22.1 0.4 0.12 12.5 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCM05134.1 - 0.00028 21.0 2.6 0.038 14.3 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CCM05134.1 - 0.067 13.3 1.5 3.3 7.9 1.6 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CCM05134.1 - 0.16 12.0 1.1 1.7 8.8 0.7 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) BTB PF00651.26 CCM05135.1 - 2.8e-07 30.4 0.0 1.5e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain AAA_10 PF12846.2 CCM05135.1 - 0.075 12.4 0.1 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain zf-RING_2 PF13639.1 CCM05137.1 - 6.2e-06 25.9 6.7 1.7e-05 24.5 4.6 1.8 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.24 CCM05137.1 - 6.2e-05 22.6 7.1 0.00015 21.4 4.9 1.7 1 1 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 CCM05137.1 - 0.00036 20.4 5.6 0.00036 20.4 3.9 2.0 2 0 0 2 2 2 1 FANCL C-terminal domain SWIM PF04434.12 CCM05137.1 - 0.00094 18.5 0.2 0.0019 17.6 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.2 CCM05137.1 - 0.0092 16.0 3.1 0.0092 16.0 2.2 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-PHD-like PF15446.1 CCM05137.1 - 0.0096 15.2 3.5 0.0096 15.2 2.4 2.0 2 1 0 2 2 2 1 PHD/FYVE-zinc-finger like domain EURL PF06937.6 CCM05137.1 - 0.012 15.0 0.2 0.012 15.0 0.2 1.6 2 0 0 2 2 2 0 EURL protein PHD_2 PF13831.1 CCM05137.1 - 0.027 13.7 5.7 0.23 10.7 4.1 2.3 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 CCM05137.1 - 0.027 14.5 7.2 0.027 14.5 5.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 CCM05137.1 - 0.067 12.9 7.7 0.066 12.9 2.3 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.1 CCM05137.1 - 0.81 9.4 10.9 0.039 13.6 3.5 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM05137.1 - 7.9 6.3 13.4 0.25 11.1 4.8 1.9 2 0 0 2 2 2 0 zinc-RING finger domain CHAT PF12770.2 CCM05138.1 - 4.9e-33 114.4 0.0 1.1e-32 113.3 0.0 1.6 2 0 0 2 2 2 1 CHAT domain TPR_11 PF13414.1 CCM05138.1 - 1.4e-11 43.8 4.5 0.064 12.9 0.0 7.8 6 2 2 8 8 8 3 TPR repeat TPR_12 PF13424.1 CCM05138.1 - 6e-07 29.3 3.7 0.21 11.5 0.0 7.2 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCM05138.1 - 1.8e-05 24.9 7.0 12 6.8 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCM05138.1 - 0.00017 22.1 4.1 12 6.7 0.0 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM05138.1 - 0.0015 18.2 1.4 6.5 6.8 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCM05138.1 - 0.0021 17.8 13.6 8.9 6.5 0.1 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCM05138.1 - 0.025 14.2 12.1 4.9 6.9 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCM05138.1 - 0.12 12.9 5.8 24 5.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCM05138.1 - 0.24 11.2 6.7 71 3.5 0.0 6.9 8 1 1 9 9 9 0 Tetratricopeptide repeat IIGP PF05049.8 CCM05139.1 - 2.7e-22 79.1 0.0 5.3e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 CCM05139.1 - 5.3e-06 26.3 0.0 1.6e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CCM05139.1 - 0.0013 18.1 0.6 0.003 17.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 CCM05139.1 - 0.0018 18.7 0.0 0.0079 16.6 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CCM05139.1 - 0.0059 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCM05139.1 - 0.02 14.3 0.4 0.048 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 CCM05139.1 - 0.02 15.1 0.1 0.02 15.1 0.0 3.3 3 1 0 3 3 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 CCM05139.1 - 0.029 13.8 1.1 0.047 13.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_21 PF13304.1 CCM05139.1 - 0.032 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2005 PF09407.5 CCM05139.1 - 0.039 12.7 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2005) AAA_17 PF13207.1 CCM05139.1 - 0.13 13.0 0.2 0.13 13.0 0.1 2.8 2 2 0 2 2 1 0 AAA domain AAA_23 PF13476.1 CCM05139.1 - 0.93 9.7 0.0 0.93 9.7 0.0 3.4 3 1 0 4 4 2 0 AAA domain IIGP PF05049.8 CCM05140.1 - 1.8e-20 73.1 0.0 2.8e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 CCM05140.1 - 7.1e-05 22.7 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCM05140.1 - 0.0046 16.1 0.0 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCM05140.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCM05140.1 - 0.026 14.7 0.0 0.026 14.7 0.0 3.0 3 1 0 3 3 3 0 ABC transporter AAA_21 PF13304.1 CCM05140.1 - 0.067 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CCM05140.1 - 0.1 13.1 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein p450 PF00067.17 CCM05142.1 - 4.2e-09 35.4 0.0 4.7e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 CCM05143.1 - 4.6e-14 52.2 0.5 7.9e-14 51.4 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCM05143.1 - 7e-07 28.9 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CCM05143.1 - 1.1e-05 25.4 0.2 1.8e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCM05143.1 - 8.7e-05 22.5 0.0 0.00019 21.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCM05143.1 - 0.0012 18.9 0.2 0.0022 18.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CCM05143.1 - 0.034 13.7 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUC153 PF08159.7 CCM05143.1 - 0.059 12.9 0.1 0.18 11.3 0.1 1.8 1 0 0 1 1 1 0 NUC153 domain ESSS PF10183.4 CCM05144.1 - 3.4e-24 85.2 0.2 3.5e-24 85.2 0.2 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GTP_EFTU PF00009.22 CCM05145.1 - 4.8e-59 198.9 0.3 8.3e-59 198.1 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GCV_H PF01597.14 CCM05145.1 - 7.4e-38 128.9 0.1 1.5e-37 128.0 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein GTP_EFTU_D3 PF03143.12 CCM05145.1 - 3.6e-23 81.6 0.0 2.1e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCM05145.1 - 4.9e-18 65.0 3.3 1.2e-17 63.8 2.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCM05145.1 - 1.2e-05 25.2 0.1 8.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Biotin_lipoyl PF00364.17 CCM05145.1 - 0.0013 18.3 0.2 0.0013 18.3 0.1 2.6 3 0 0 3 3 3 1 Biotin-requiring enzyme Miro PF08477.8 CCM05145.1 - 0.0015 19.0 0.0 0.0037 17.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 CCM05145.1 - 0.0041 16.7 0.4 0.013 15.1 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 RnfC_N PF13375.1 CCM05145.1 - 0.012 15.2 0.1 0.036 13.7 0.1 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain cobW PF02492.14 CCM05145.1 - 0.032 13.6 0.7 0.057 12.8 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CCM05145.1 - 0.039 13.4 0.3 7.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M23 PF01551.17 CCM05145.1 - 0.095 12.7 0.2 4.2 7.4 0.0 2.9 1 1 1 2 2 2 0 Peptidase family M23 CbiA PF01656.18 CCM05145.1 - 0.11 11.8 1.1 9.1 5.6 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 CCM05145.1 - 0.14 11.8 0.7 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pex14_N PF04695.8 CCM05146.1 - 4.9e-28 97.8 1.0 4.9e-28 97.8 0.7 2.4 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ING PF12998.2 CCM05146.1 - 0.00026 21.2 7.0 0.00064 19.9 4.8 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Mt_ATP-synt_D PF05873.7 CCM05146.1 - 0.0004 20.0 2.8 0.00065 19.3 1.9 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) zf-C4H2 PF10146.4 CCM05146.1 - 0.0013 18.7 3.7 0.0013 18.7 2.6 1.5 2 0 0 2 2 1 1 Zinc finger-containing protein DUF1759 PF03564.10 CCM05146.1 - 0.0014 18.4 0.6 0.0014 18.4 0.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1759) Laminin_I PF06008.9 CCM05146.1 - 0.0043 16.4 11.8 0.0078 15.5 8.2 1.4 1 0 0 1 1 1 1 Laminin Domain I IncA PF04156.9 CCM05146.1 - 0.0046 16.5 5.0 0.0088 15.6 3.4 1.5 1 0 0 1 1 1 1 IncA protein AAA_13 PF13166.1 CCM05146.1 - 0.0078 14.7 3.4 0.011 14.3 2.4 1.1 1 0 0 1 1 1 1 AAA domain IFT57 PF10498.4 CCM05146.1 - 0.013 14.2 9.9 0.043 12.5 4.8 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Filament PF00038.16 CCM05146.1 - 0.014 14.9 10.3 0.022 14.2 7.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein Mnd1 PF03962.10 CCM05146.1 - 0.02 14.5 5.4 0.039 13.6 3.8 1.5 1 0 0 1 1 1 0 Mnd1 family Zwint PF15556.1 CCM05146.1 - 0.028 13.6 8.5 0.043 13.0 5.9 1.2 1 0 0 1 1 1 0 ZW10 interactor DUF342 PF03961.8 CCM05146.1 - 0.033 12.5 2.7 0.046 12.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2317 PF10079.4 CCM05146.1 - 0.037 12.6 6.9 0.052 12.1 4.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Prominin PF05478.6 CCM05146.1 - 0.056 10.9 2.4 0.076 10.5 1.7 1.1 1 0 0 1 1 1 0 Prominin Z1 PF10593.4 CCM05146.1 - 0.07 12.3 2.0 0.11 11.7 1.4 1.2 1 0 0 1 1 1 0 Z1 domain Pox_F16 PF04708.7 CCM05146.1 - 0.081 12.1 0.3 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein ALMT PF11744.3 CCM05146.1 - 0.088 11.4 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PMSI1 PF15322.1 CCM05146.1 - 0.089 11.8 4.6 0.14 11.2 3.2 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Methyltransf_14 PF08484.6 CCM05146.1 - 0.095 12.2 2.3 0.16 11.5 1.6 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Rsd_AlgQ PF04353.8 CCM05146.1 - 0.1 12.2 5.2 0.068 12.8 1.5 1.9 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ V_ATPase_I PF01496.14 CCM05146.1 - 0.11 10.3 4.8 0.15 9.8 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mitofilin PF09731.4 CCM05146.1 - 0.14 10.7 11.9 0.058 12.0 5.0 2.0 1 1 1 2 2 2 0 Mitochondrial inner membrane protein Phage_GPO PF05929.6 CCM05146.1 - 0.15 11.2 4.0 0.23 10.6 2.8 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TBPIP PF07106.8 CCM05146.1 - 0.17 11.4 10.2 0.3 10.6 7.1 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LXG PF04740.7 CCM05146.1 - 0.2 11.3 8.9 0.35 10.6 6.1 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Laminin_II PF06009.7 CCM05146.1 - 0.24 11.1 13.3 0.059 13.1 6.6 1.8 2 0 0 2 2 2 0 Laminin Domain II GAS PF13851.1 CCM05146.1 - 0.27 10.4 15.6 0.39 9.8 6.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 CCM05146.1 - 0.27 11.3 7.8 0.51 10.4 5.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4613 PF15390.1 CCM05146.1 - 0.27 9.3 3.9 0.37 8.9 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) FH2 PF02181.18 CCM05146.1 - 0.36 9.6 7.6 0.57 9.0 5.3 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain APG6 PF04111.7 CCM05146.1 - 0.37 9.7 13.8 0.61 9.0 9.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF334 PF03904.8 CCM05146.1 - 0.74 9.0 8.5 0.13 11.5 3.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF334) DUF1002 PF06207.6 CCM05146.1 - 0.96 8.7 6.4 1.5 8.0 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF948 PF06103.6 CCM05146.1 - 1 9.2 3.9 1.9 8.3 2.4 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.3 CCM05146.1 - 1 6.5 10.7 1.4 6.1 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.8 CCM05146.1 - 1.1 8.2 3.8 1.6 7.7 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein YkuI_C PF10388.4 CCM05146.1 - 1.1 8.9 8.2 8.5 6.0 0.0 3.1 3 1 1 4 4 4 0 EAL-domain associated signalling protein domain Atg14 PF10186.4 CCM05146.1 - 1.5 7.7 10.0 2.6 6.9 6.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MutS_III PF05192.13 CCM05146.1 - 1.7 8.3 4.8 6.1 6.5 3.7 1.6 1 1 0 1 1 1 0 MutS domain III HALZ PF02183.13 CCM05146.1 - 2.6 7.8 7.1 19 5.0 0.4 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF1664 PF07889.7 CCM05146.1 - 3.1 7.5 10.8 26 4.6 6.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 CCM05146.1 - 3.3 7.5 14.3 1.1 9.1 2.6 2.6 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vma12 PF11712.3 CCM05146.1 - 3.5 7.3 5.7 5 6.8 3.4 1.7 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Med9 PF07544.8 CCM05146.1 - 4.6 7.0 12.1 22 4.8 0.9 3.2 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2203 PF09969.4 CCM05146.1 - 6.7 6.9 7.6 19 5.4 5.3 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) NPV_P10 PF05531.7 CCM05146.1 - 7.8 6.8 15.0 2.2 8.5 4.5 3.5 3 1 1 4 4 2 0 Nucleopolyhedrovirus P10 protein Med5 PF08689.5 CCM05148.1 - 3.9e-17 61.3 0.0 3.9e-17 61.3 0.0 2.6 2 1 0 2 2 2 1 Mediator complex subunit Med5 GRIP PF01465.15 CCM05148.1 - 3.3e-07 29.7 0.2 8.9e-07 28.3 0.1 1.8 1 0 0 1 1 1 1 GRIP domain Cation_efflux PF01545.16 CCM05149.1 - 1.5e-81 273.6 4.5 2.8e-81 272.7 3.1 1.4 1 1 0 1 1 1 1 Cation efflux family JAB PF01398.16 CCM05150.1 - 1.2e-09 37.8 0.0 2.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DPBB_1 PF03330.13 CCM05151.1 - 5.7e-06 26.2 1.0 2.6e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Ipi1_N PF12333.3 CCM05152.1 - 1e-13 51.1 0.0 6.4e-11 42.1 0.0 3.5 2 1 2 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 CCM05152.1 - 6.9e-05 23.0 0.2 0.0025 18.0 0.0 2.8 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 CCM05152.1 - 0.048 14.1 0.2 0.39 11.2 0.1 2.7 2 0 0 2 2 2 0 HEAT-like repeat Cellulase PF00150.13 CCM05153.1 - 1.1e-17 64.1 0.2 1.5e-17 63.7 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 CCM05153.1 - 6.7e-06 26.4 0.0 2.9e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Sugar-binding cellulase-like DUF4038 PF13204.1 CCM05153.1 - 0.00019 20.8 0.1 0.00034 20.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) RNase_T PF00929.19 CCM05154.1 - 1.5e-24 87.1 0.0 2.6e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease E1_DerP2_DerF2 PF02221.10 CCM05154.1 - 4.8e-23 81.8 0.0 8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 ML domain MRAP PF15183.1 CCM05155.1 - 0.0095 15.5 0.2 0.18 11.4 0.1 2.2 2 0 0 2 2 2 1 Melanocortin-2 receptor accessory protein family Tetraspannin PF00335.15 CCM05155.1 - 0.014 14.7 4.6 0.058 12.6 3.4 1.8 2 0 0 2 2 2 0 Tetraspanin family ADH_N PF08240.7 CCM05158.1 - 9.3e-30 102.6 0.7 1.6e-29 101.8 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM05158.1 - 9.8e-13 47.7 0.0 3.5e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 CCM05158.1 - 7e-05 22.4 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 CCM05158.1 - 0.00086 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 CCM05158.1 - 0.0023 18.4 0.0 0.0054 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM05158.1 - 0.0084 16.5 0.0 0.025 15.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain F420_oxidored PF03807.12 CCM05158.1 - 0.026 14.9 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FANCL_C PF11793.3 CCM05158.1 - 0.051 13.5 0.4 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain SGL PF08450.7 CCM05159.1 - 3.1e-44 151.2 0.0 4.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Ribosomal_L17 PF01196.14 CCM05159.1 - 7.7e-33 112.9 0.0 1.5e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 PP-binding PF00550.20 CCM05159.1 - 4e-12 46.2 0.6 6.9e-12 45.4 0.4 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CCM05159.1 - 1.1e-08 35.0 0.8 2.2e-08 34.0 0.4 1.6 1 1 0 1 1 1 1 Acyl-carrier Arylesterase PF01731.15 CCM05159.1 - 0.0023 17.8 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Arylesterase Ribosomal_L13 PF00572.13 CCM05160.1 - 5.2e-27 94.4 0.0 7.6e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 KH_1 PF00013.24 CCM05161.1 - 8.4e-40 134.2 9.3 1.2e-15 56.9 0.2 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCM05161.1 - 1.8e-28 97.6 9.7 3e-10 39.5 1.1 3.7 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 CCM05161.1 - 1.4e-10 40.5 1.7 0.007 15.9 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCM05161.1 - 1.9e-10 40.2 0.2 0.029 13.9 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 CCM05161.1 - 0.00019 21.1 3.0 0.13 12.1 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain NUFIP1 PF10453.4 CCM05162.1 - 2.4e-16 58.9 0.2 5e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) API5 PF05918.6 CCM05162.1 - 2 6.8 3.4 2.9 6.3 2.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Peptidase_M16_C PF05193.16 CCM05163.1 - 1.2e-17 64.1 0.0 2.6e-09 37.0 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCM05163.1 - 1.7e-06 27.8 0.0 0.0002 21.1 0.0 2.7 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) PDT PF00800.13 CCM05164.1 - 1.5e-47 161.5 0.0 1.9e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase p450 PF00067.17 CCM05165.1 - 1.8e-51 175.1 0.0 6.7e-51 173.2 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 zf-CCCH PF00642.19 CCM05166.1 - 7.8e-15 54.1 28.7 4.4e-05 23.0 0.4 4.8 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 CCM05166.1 - 0.00015 21.5 4.7 0.00057 19.6 3.3 2.1 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCM05166.1 - 0.0062 16.2 1.2 0.016 14.9 0.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.1 CCM05166.1 - 0.068 13.1 0.3 0.068 13.1 0.2 5.2 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type DUF1115 PF06544.7 CCM05166.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) Fungal_trans PF04082.13 CCM05167.1 - 8.4e-11 41.2 0.0 1.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UPF0047 PF01894.12 CCM05168.1 - 2.6e-18 65.9 0.0 2.9e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RhoGEF PF00621.15 CCM05170.1 - 6.3e-16 58.7 0.0 9.6e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain RAP1 PF07218.6 CCM05170.1 - 8.9 4.2 6.1 18 3.2 4.2 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Exo_endo_phos PF03372.18 CCM05171.1 - 1.2e-13 51.5 0.1 1.7e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Acyltransferase PF01553.16 CCM05171.1 - 0.028 13.8 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase Ras PF00071.17 CCM05172.1 - 4.9e-39 133.3 0.0 5.9e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM05172.1 - 3.1e-10 40.5 0.0 4.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CCM05172.1 - 0.0036 16.7 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CCM05172.1 - 0.032 13.4 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family His_Phos_1 PF00300.17 CCM05173.1 - 2.3e-28 99.2 0.1 2.8e-28 98.9 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) IncA PF04156.9 CCM05174.1 - 0.0022 17.5 8.0 0.0022 17.5 5.5 7.9 2 1 4 6 6 6 3 IncA protein Tropomyosin_1 PF12718.2 CCM05174.1 - 0.0061 16.4 24.3 0.0061 16.4 16.9 7.1 2 2 3 6 6 6 2 Tropomyosin like F-box-like PF12937.2 CCM05175.1 - 9.2e-05 22.0 0.2 0.00037 20.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like Mito_carr PF00153.22 CCM05176.1 - 1.1e-29 102.0 10.0 3.4e-14 52.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.7 CCM05177.1 - 1.1e-10 40.9 1.3 1.8e-10 40.3 0.4 1.7 1 1 0 1 1 1 1 Mpv17 / PMP22 family Amidase02_C PF12123.3 CCM05177.1 - 0.14 11.7 0.2 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase TRAPPC-Trs85 PF12739.2 CCM05178.1 - 9.8e-27 93.6 0.1 7e-20 71.0 0.0 2.7 2 1 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.12 CCM05178.1 - 0.008 16.0 1.7 3.5 7.7 0.0 3.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TRAPPC9-Trs120 PF08626.6 CCM05178.1 - 0.041 11.2 0.0 0.29 8.4 0.0 1.9 1 1 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_16 PF13432.1 CCM05178.1 - 0.042 14.5 0.1 2.4 8.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MBD PF01429.14 CCM05179.1 - 0.0048 16.3 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 2 Methyl-CpG binding domain LCCL PF03815.14 CCM05180.1 - 4.3e-15 55.4 0.0 7.4e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Limkain-b1 PF11608.3 CCM05181.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Seipin PF06775.9 CCM05183.1 - 2.3e-14 53.3 0.0 4.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) SH3BGR PF04908.10 CCM05184.1 - 4.7e-06 26.4 0.1 1.4e-05 24.9 0.0 1.7 1 1 1 2 2 2 1 SH3-binding, glutamic acid-rich protein Aldedh PF00171.17 CCM05185.1 - 4.3e-127 424.2 0.1 4.9e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCM05185.1 - 0.0012 17.6 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) LMWPc PF01451.16 CCM05186.1 - 3.9e-20 72.5 0.0 4.3e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pox_MCEL PF03291.11 CCM05186.1 - 0.016 14.0 0.0 0.019 13.8 0.0 1.0 1 0 0 1 1 1 0 mRNA capping enzyme GDI PF00996.13 CCM05188.1 - 2.9e-206 684.9 0.0 3.3e-206 684.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor TipAS PF07739.8 CCM05188.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Rav1p_C PF12234.3 CCM05189.1 - 1.3e-188 628.1 0.0 2.4e-188 627.2 0.0 1.4 1 1 0 1 1 1 1 RAVE protein 1 C terminal Fasciclin PF02469.17 CCM05190.1 - 1.7e-66 222.0 0.0 1.2e-16 60.9 0.0 5.5 5 1 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.22 CCM05191.1 - 2.7e-66 219.2 5.7 8.6e-22 76.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Not3 PF04065.10 CCM05192.1 - 0.23 10.7 0.2 1 8.5 0.0 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF619 PF04768.8 CCM05193.1 - 3e-36 124.4 0.0 4.6e-21 74.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF619) F-box-like PF12937.2 CCM05194.1 - 6.2e-06 25.8 0.7 1.4e-05 24.7 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM05194.1 - 0.059 13.0 0.6 0.2 11.3 0.4 1.9 1 0 0 1 1 1 0 F-box domain UQ_con PF00179.21 CCM05195.1 - 2.2e-20 72.4 0.0 3.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SKN1 PF03935.10 CCM05196.1 - 1.4e-187 623.9 6.1 1.6e-187 623.6 4.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Imm44 PF15584.1 CCM05196.1 - 0.029 14.2 0.3 3.4 7.5 0.1 2.4 2 0 0 2 2 2 0 Immunity protein 44 SNAPc_SNAP43 PF09808.4 CCM05197.1 - 1.4e-05 24.8 0.1 3.2e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ima1_N PF09779.4 CCM05198.1 - 8.2e-16 58.6 0.1 1.3e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain Tox-PL PF15644.1 CCM05198.1 - 0.046 14.4 0.0 0.087 13.5 0.0 1.4 1 0 0 1 1 1 0 Papain fold toxin 1 Nucleoporin_C PF03177.9 CCM05199.1 - 1.6e-75 254.8 0.0 2.1e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCM05199.1 - 4.7e-58 196.9 0.0 6.6e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Ribonucleas_3_3 PF14622.1 CCM05200.1 - 1.3e-10 41.3 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CCM05200.1 - 9.7e-10 38.9 0.0 2.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain HORMA PF02301.13 CCM05201.1 - 1.6e-36 125.7 0.0 1.9e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 CCM05201.1 - 0.0047 16.3 0.3 0.021 14.2 0.2 1.9 1 1 0 1 1 1 1 Autophagy-related protein 13 NAD_binding_6 PF08030.7 CCM05202.1 - 6.2e-25 87.9 0.0 1.1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CCM05202.1 - 3.4e-21 75.0 0.0 6.6e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CCM05202.1 - 2.2e-14 53.6 16.7 4.7e-14 52.5 11.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 CCM05202.1 - 0.0016 18.5 0.0 0.0076 16.3 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCM05202.1 - 0.0029 18.1 0.0 0.13 12.8 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain WD40 PF00400.27 CCM05203.1 - 1.1e-40 136.0 5.9 4.5e-10 39.0 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CCM05203.1 - 1.5e-30 106.1 0.0 5.3e-30 104.3 0.0 1.8 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit LisH PF08513.6 CCM05203.1 - 0.0081 15.8 0.1 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 LisH Nup160 PF11715.3 CCM05203.1 - 0.028 12.5 0.1 0.81 7.7 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCM05203.1 - 0.062 11.5 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Syndecan PF01034.15 CCM05205.1 - 0.016 14.8 0.5 0.029 14.0 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.11 CCM05205.1 - 0.064 11.5 0.1 0.095 10.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Bacteriocin_IIc PF10439.4 CCM05205.1 - 1.7 8.8 7.3 0.54 10.4 1.5 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide FA_desaturase PF00487.19 CCM05206.1 - 1.6e-32 112.9 26.2 3.8e-32 111.7 18.1 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCM05206.1 - 3.5e-11 42.7 0.0 8.4e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CbtA PF09490.5 CCM05206.1 - 0.029 13.6 0.8 0.055 12.7 0.6 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Ribosomal_L13e PF01294.13 CCM05207.1 - 7e-64 214.5 3.3 1e-63 214.0 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Meth_synt_2 PF01717.13 CCM05208.1 - 4e-19 68.7 0.0 4.5e-18 65.3 0.0 2.0 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCM05208.1 - 3.8e-07 29.6 0.0 3.9e-05 23.0 0.0 3.1 2 1 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain DUF445 PF04286.7 CCM05209.1 - 0.052 13.0 0.3 0.088 12.3 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) SlyX PF04102.7 CCM05209.1 - 5.7 7.4 6.2 29 5.1 1.2 3.1 2 2 2 4 4 4 0 SlyX Rossmann-like PF10727.4 CCM05210.1 - 0.049 13.3 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain DUF202 PF02656.10 CCM05210.1 - 0.07 13.3 3.5 0.95 9.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF4131 PF13567.1 CCM05210.1 - 8.4 5.7 7.8 1.2e+02 1.9 5.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ER_lumen_recept PF00810.13 CCM05211.1 - 5.6e-57 192.3 11.1 1.6e-56 190.8 7.7 1.7 1 0 0 1 1 1 1 ER lumen protein retaining receptor Lectin_leg-like PF03388.8 CCM05211.1 - 7.3e-33 113.6 0.0 1.1e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family DnaJ PF00226.26 CCM05212.1 - 5.9e-14 51.5 0.1 9.2e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Clathrin_lg_ch PF01086.12 CCM05213.1 - 5.5e-43 147.4 6.1 7.3e-41 140.5 4.2 2.0 1 1 0 1 1 1 1 Clathrin light chain Ribosomal_L30_N PF08079.7 CCM05213.1 - 4.7 7.3 12.8 8.8 6.4 8.9 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain LRR_8 PF13855.1 CCM05214.1 - 2.8e-10 39.8 15.0 2.5e-06 27.1 0.9 4.1 2 2 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 CCM05214.1 - 5.8e-08 32.1 20.0 0.0012 18.4 1.7 5.0 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCM05214.1 - 7.4e-06 25.2 7.9 0.65 10.2 0.0 6.4 6 0 0 6 6 6 1 Leucine Rich Repeat LRRNT_2 PF08263.7 CCM05214.1 - 0.019 14.9 0.3 0.06 13.3 0.2 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 CCM05214.1 - 0.037 13.7 2.9 0.061 13.0 0.9 2.1 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) DUF1510 PF07423.6 CCM05214.1 - 0.19 11.0 0.0 0.44 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) LRR_6 PF13516.1 CCM05214.1 - 0.29 11.3 10.4 3 8.1 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 CCM05214.1 - 5.8 7.5 10.9 7.5 7.2 0.4 5.5 5 1 0 5 5 5 0 Leucine rich repeat Calpain_III PF01067.17 CCM05215.1 - 7.2e-26 90.5 0.1 6.5e-13 48.5 0.0 4.0 2 2 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 CCM05215.1 - 2.6e-08 33.2 0.0 6e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease MIT PF04212.13 CCM05215.1 - 4.1e-05 23.3 1.8 7.2e-05 22.5 1.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Init_tRNA_PT PF04179.7 CCM05216.1 - 1.6e-88 297.5 0.0 2.6e-88 296.8 0.0 1.3 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DSPc PF00782.15 CCM05216.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Med9 PF07544.8 CCM05217.1 - 0.00083 19.0 2.1 0.0022 17.6 0.7 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF4203 PF13886.1 CCM05218.1 - 5e-08 32.6 18.6 7.9e-08 32.0 12.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) FAD_binding_3 PF01494.14 CCM05219.1 - 2.3e-77 260.4 0.0 2.9e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 CCM05219.1 - 0.00017 20.5 1.6 0.00048 19.1 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CCM05219.1 - 0.00029 19.9 0.1 0.00056 19.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 CCM05219.1 - 0.00047 20.5 0.1 0.19 12.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCM05219.1 - 0.00053 19.9 0.0 0.0019 18.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCM05219.1 - 0.00078 18.6 0.4 0.0059 15.7 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCM05219.1 - 0.001 19.0 0.1 0.003 17.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCM05219.1 - 0.0011 17.4 0.3 0.0039 15.7 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 CCM05219.1 - 0.0017 17.3 1.1 0.19 10.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCM05219.1 - 0.03 14.3 0.0 0.083 12.9 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCM05219.1 - 0.079 12.0 0.0 0.46 9.4 0.0 2.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.17 CCM05219.1 - 0.091 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CCM05220.1 - 9.1e-75 251.9 0.0 1.2e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 CCM05220.1 - 1.2e-05 24.3 0.1 0.0015 17.4 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 CCM05220.1 - 6.4e-05 23.2 0.0 0.0053 17.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM05220.1 - 0.00063 19.7 0.1 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCM05220.1 - 0.0016 18.3 0.0 0.013 15.3 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM05220.1 - 0.0016 18.5 0.1 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM05220.1 - 0.0017 16.9 0.1 0.0037 15.7 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 CCM05220.1 - 0.0039 16.3 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 CCM05220.1 - 0.012 14.5 0.2 0.023 13.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 CCM05220.1 - 0.016 14.1 0.2 0.14 11.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1212 PF06738.7 CCM05223.1 - 1.2e-38 132.5 1.0 1.2e-38 132.5 0.7 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CCM05223.1 - 2.5e-14 53.3 6.6 2.5e-14 53.3 4.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Saccharop_dh PF03435.13 CCM05225.1 - 2.5e-109 365.8 0.1 8.6e-109 364.0 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 CCM05225.1 - 2.8e-91 304.8 0.0 7.7e-91 303.4 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 CCM05225.1 - 1.6e-09 37.9 0.2 5.7e-08 32.9 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 CCM05225.1 - 1.8e-05 25.2 0.0 8.4e-05 23.1 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM05225.1 - 0.00097 19.5 0.0 0.048 14.1 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 CCM05225.1 - 0.0015 18.5 0.7 0.0038 17.2 0.4 1.8 2 0 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 CCM05225.1 - 0.0045 17.3 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MTS PF05175.9 CCM05225.1 - 0.024 14.0 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain GFO_IDH_MocA PF01408.17 CCM05225.1 - 0.12 12.9 0.3 0.47 10.9 0.1 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Prenyltrans PF00432.16 CCM05226.1 - 1e-29 101.7 13.1 6e-08 32.1 0.2 6.3 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCM05226.1 - 3e-16 59.8 0.0 1.9e-11 44.3 0.0 3.6 2 2 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCM05226.1 - 0.025 14.5 0.0 0.52 10.3 0.0 3.0 2 1 2 4 4 4 0 Prenyltransferase-like F-box-like PF12937.2 CCM05227.1 - 4.2e-08 32.7 2.3 6.2e-08 32.2 0.1 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 CCM05227.1 - 0.00019 21.0 0.1 0.00072 19.1 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCM05228.1 - 8.6e-09 34.9 0.3 1.8e-07 30.7 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM05228.1 - 0.013 15.1 0.6 0.013 15.1 0.4 2.7 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.2 CCM05228.1 - 0.22 11.1 10.9 3 7.5 0.0 5.8 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CCM05228.1 - 2.1 8.6 6.8 56 4.2 0.0 6.1 8 0 0 8 8 8 0 Leucine Rich repeat ADH_N PF08240.7 CCM05229.1 - 2.9e-19 68.8 0.4 5e-19 68.0 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCM05229.1 - 9.1e-15 54.3 0.0 1.4e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3348 PF11828.3 CCM05230.1 - 0.022 14.1 0.5 0.028 13.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Pyr_redox_3 PF13738.1 CCM05231.1 - 3e-20 73.1 0.0 1.7e-19 70.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCM05231.1 - 8.3e-20 70.4 0.0 1e-16 60.3 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CCM05231.1 - 1.6e-13 50.9 0.0 1.2e-09 38.3 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM05231.1 - 6.8e-11 41.6 0.2 5.7e-08 32.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 CCM05231.1 - 3.6e-05 22.9 0.1 0.00014 21.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CCM05231.1 - 6.5e-05 21.9 0.0 0.004 16.0 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM05231.1 - 8.9e-05 22.3 0.0 0.17 11.6 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CCM05231.1 - 0.00011 22.0 0.1 0.00043 20.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 CCM05231.1 - 0.00032 20.7 0.6 0.086 12.9 0.1 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CCM05231.1 - 0.00033 21.0 0.9 0.015 15.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM05231.1 - 0.0014 17.6 0.6 0.02 13.8 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 CCM05231.1 - 0.0017 17.5 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 CCM05231.1 - 0.0023 16.4 0.1 0.0023 16.4 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 CCM05231.1 - 0.0032 16.3 6.8 0.15 10.9 0.0 2.7 3 1 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 CCM05231.1 - 0.011 15.9 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 CCM05231.1 - 0.011 14.5 1.5 0.026 13.3 1.1 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 CCM05231.1 - 0.022 13.8 0.9 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 CCM05231.1 - 0.022 14.3 0.1 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 CCM05231.1 - 0.035 13.1 0.2 0.062 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ABM PF03992.11 CCM05232.1 - 1.5e-08 34.5 0.3 1.8e-08 34.2 0.2 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Lactamase_B_2 PF12706.2 CCM05233.1 - 1.6e-10 40.8 0.0 3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3446 PF11928.3 CCM05233.1 - 0.0022 18.1 0.3 0.0022 18.1 0.2 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3446) Sugar_tr PF00083.19 CCM05234.1 - 5.9e-97 325.0 27.3 7e-97 324.8 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM05234.1 - 8.1e-24 83.9 30.2 8.9e-23 80.5 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_binding_1 PF01035.15 CCM05235.1 - 1.8e-12 46.7 0.0 2.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4224 PF13986.1 CCM05235.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) HET PF06985.6 CCM05236.1 - 4e-16 59.4 0.4 3e-13 50.1 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) G-alpha PF00503.15 CCM05237.1 - 2.2e-115 385.4 0.0 2.8e-115 385.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCM05237.1 - 2.2e-13 49.8 0.0 4.6e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 CCM05237.1 - 0.00066 19.1 0.0 0.0019 17.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 CCM05237.1 - 0.018 15.5 0.0 2.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DUF815 PF05673.8 CCM05237.1 - 0.058 12.3 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GTP_EFTU PF00009.22 CCM05237.1 - 0.071 12.5 0.0 12 5.2 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain FmdA_AmdA PF03069.10 CCM05238.1 - 1.8e-56 191.4 0.0 8.2e-32 110.3 0.1 2.3 1 1 1 2 2 2 2 Acetamidase/Formamidase family PCNA_N PF00705.13 CCM05240.1 - 6.5e-51 171.1 3.1 1.4e-50 170.0 2.2 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CCM05240.1 - 9.7e-43 145.1 0.2 4.1e-20 72.0 0.0 2.7 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CCM05240.1 - 2.3e-08 33.4 0.0 1.6e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Rad9 Daxx PF03344.10 CCM05240.1 - 0.12 10.8 23.2 0.15 10.4 16.1 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CCM05240.1 - 0.39 8.5 32.7 0.35 8.7 21.9 1.4 2 0 0 2 2 2 0 Nop14-like family Hus1 PF04005.7 CCM05240.1 - 0.77 8.6 7.3 1.3 7.8 0.0 3.6 3 1 1 4 4 4 0 Hus1-like protein BUD22 PF09073.5 CCM05240.1 - 1.3 7.9 34.1 1.8 7.5 23.6 1.1 1 0 0 1 1 1 0 BUD22 Mod_r PF07200.8 CCM05241.1 - 0.18 11.7 0.1 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TatD_DNase PF01026.16 CCM05242.1 - 2.5e-43 148.1 0.0 3.1e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CCM05242.1 - 0.00081 19.0 0.1 0.0023 17.5 0.0 2.0 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 CCM05242.1 - 0.025 14.2 0.1 0.67 9.5 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family p450 PF00067.17 CCM05245.1 - 2.7e-66 223.9 0.0 1.2e-63 215.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 GMC_oxred_N PF00732.14 CCM05247.1 - 1.1e-42 146.1 0.0 6.9e-41 140.3 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM05247.1 - 1.6e-29 103.0 0.0 2.7e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM05247.1 - 0.00066 18.6 0.2 0.002 17.1 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCM05247.1 - 0.00096 19.1 0.1 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCM05247.1 - 0.0017 17.2 0.1 0.0074 15.1 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 CCM05247.1 - 0.0063 15.4 0.1 0.009 14.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CCM05247.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 CCM05247.1 - 0.098 12.5 0.1 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM05247.1 - 0.11 12.4 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM05247.1 - 0.13 10.6 0.1 0.55 8.6 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 CCM05249.1 - 1.1e-06 27.6 9.7 9.4e-06 24.5 6.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily GMC_oxred_N PF00732.14 CCM05250.1 - 1.6e-54 185.1 0.0 2.1e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM05250.1 - 3.3e-33 115.0 0.0 5.2e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM05250.1 - 4.5e-05 22.5 0.3 0.00056 18.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCM05250.1 - 0.00021 20.2 3.8 0.0026 16.6 2.6 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCM05250.1 - 0.0022 17.9 0.2 0.0053 16.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CCM05250.1 - 0.0066 15.4 0.0 0.0096 14.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CCM05250.1 - 0.0079 16.2 0.1 1.2 9.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM05250.1 - 0.021 13.3 0.1 0.57 8.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 CCM05250.1 - 0.022 14.6 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM05250.1 - 0.14 11.2 0.2 0.27 10.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Abhydrolase_3 PF07859.8 CCM05251.1 - 1.3e-25 90.2 0.0 1.7e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCM05251.1 - 2.3e-11 42.9 0.0 5.1e-11 41.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCM05251.1 - 0.0024 17.6 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 CCM05253.1 - 1.3e-56 191.9 0.4 1.1e-55 188.8 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CCM05253.1 - 8.1e-40 137.0 0.0 1.3e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 CCM05253.1 - 2.4e-34 118.3 0.0 3.6e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 CCM05253.1 - 4.4e-34 117.7 0.4 2.5e-30 105.4 0.0 2.8 2 1 0 2 2 2 2 KR domain adh_short PF00106.20 CCM05253.1 - 1.8e-32 112.5 1.3 1.4e-28 99.9 0.0 3.2 3 0 0 3 3 3 2 short chain dehydrogenase PS-DH PF14765.1 CCM05253.1 - 1.6e-30 106.3 0.0 3.9e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 CCM05253.1 - 2.9e-28 98.1 0.0 1.1e-27 96.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 CCM05253.1 - 5.9e-11 42.2 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CCM05253.1 - 5.3e-05 23.3 2.5 0.00011 22.4 0.5 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 CCM05253.1 - 0.0057 15.6 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 CCM05253.1 - 0.072 11.9 0.3 0.22 10.3 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CCM05253.1 - 0.099 11.3 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCM05256.1 - 0.00079 19.4 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CCM05256.1 - 0.027 14.7 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 CCM05256.1 - 0.057 12.8 0.0 0.089 12.2 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2564 PF10819.3 CCM05257.1 - 0.37 10.9 4.0 1.6 8.9 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) p450 PF00067.17 CCM05258.1 - 7.3e-67 225.8 0.0 1.3e-66 225.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ferritin-like PF12902.2 CCM05260.1 - 4.2e-36 124.6 0.0 5.7e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like Trp_halogenase PF04820.9 CCM05261.1 - 1.5e-17 63.3 0.9 2.2e-11 43.0 0.1 2.4 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 CCM05261.1 - 3.1e-07 29.8 1.8 0.01 14.9 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 CCM05261.1 - 1.6e-06 27.2 0.2 2.9e-06 26.4 0.1 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CCM05261.1 - 7.7e-06 25.2 0.2 2.2e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM05261.1 - 9.8e-05 21.4 1.6 0.00069 18.6 0.3 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCM05261.1 - 0.00013 20.9 1.5 0.0002 20.3 1.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCM05261.1 - 0.00063 19.6 0.1 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCM05261.1 - 0.0021 16.9 0.4 0.0037 16.1 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CCM05261.1 - 0.0027 17.6 0.2 0.0064 16.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCM05261.1 - 0.0028 16.2 0.1 0.0039 15.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 CCM05261.1 - 0.024 13.7 0.1 0.24 10.4 0.0 2.4 3 0 0 3 3 3 0 Thi4 family Pyr_redox_3 PF13738.1 CCM05261.1 - 0.16 12.0 0.4 0.28 11.2 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM05263.1 - 1.4e-23 84.0 0.1 1.8e-22 80.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCM05263.1 - 1.6e-16 59.6 0.0 4.5e-16 58.1 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CCM05263.1 - 2.5e-13 49.6 0.4 1.7e-10 40.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM05263.1 - 3.5e-09 36.8 0.0 1.5e-07 31.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCM05263.1 - 0.00046 20.0 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CCM05263.1 - 0.00083 19.3 0.3 0.0047 16.9 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCM05263.1 - 0.0014 17.7 0.2 0.0045 16.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CCM05263.1 - 0.0017 17.3 0.0 0.53 9.1 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 CCM05263.1 - 0.0018 17.2 0.3 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.13 CCM05263.1 - 0.0018 18.2 0.1 0.046 13.7 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain Shikimate_DH PF01488.15 CCM05263.1 - 0.0022 18.0 0.1 1.7 8.7 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 CCM05263.1 - 0.0032 16.0 0.2 0.0066 14.9 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 CCM05263.1 - 0.0063 15.4 0.2 0.014 14.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CCM05263.1 - 0.007 15.3 0.0 0.047 12.6 0.0 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 CCM05263.1 - 0.014 14.4 0.0 0.04 13.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 CCM05263.1 - 0.03 14.7 0.2 2.7 8.4 0.0 2.9 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 CCM05263.1 - 0.069 12.3 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 CCM05264.1 - 3.9e-57 193.6 0.0 4.9e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM05264.1 - 1.2e-36 126.2 0.1 2e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCM05264.1 - 1.7e-05 23.8 0.2 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 CCM05264.1 - 4.9e-05 23.4 0.1 0.02 14.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM05264.1 - 5.5e-05 22.2 0.1 8.4e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CCM05264.1 - 7.8e-05 22.6 0.0 0.0008 19.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCM05264.1 - 0.00014 20.9 0.2 0.0021 17.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCM05264.1 - 0.0033 17.3 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCM05264.1 - 0.0043 16.1 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CCM05264.1 - 0.013 14.6 0.1 0.1 11.6 0.0 2.1 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 CCM05264.1 - 0.02 13.4 0.1 0.032 12.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 CCM05264.1 - 0.11 12.2 0.1 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding WD40 PF00400.27 CCM05265.1 - 2.9e-158 508.8 62.0 3.1e-12 45.8 0.6 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat PQQ_3 PF13570.1 CCM05265.1 - 4.1e-18 65.0 14.2 1 9.7 0.1 12.8 9 4 5 14 14 14 5 PQQ-like domain Nup160 PF11715.3 CCM05265.1 - 1.8e-15 56.0 18.1 0.0033 15.6 0.0 10.1 4 2 5 9 9 9 6 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCM05265.1 - 6.4e-11 42.1 13.6 0.019 14.4 3.3 5.8 1 1 3 5 5 5 5 PQQ-like domain Nucleoporin_N PF08801.6 CCM05265.1 - 1.3e-08 34.0 22.2 0.033 12.9 0.5 8.3 1 1 2 5 5 5 5 Nup133 N terminal like NACHT PF05729.7 CCM05265.1 - 7.4e-07 28.9 0.0 2.1e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 CCM05265.1 - 1.7e-06 27.5 0.0 51 3.6 0.0 9.1 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 CCM05265.1 - 4.8e-06 26.6 0.1 2e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain FeThRed_A PF02941.10 CCM05265.1 - 1.6e-05 24.7 12.0 35 4.4 0.0 9.9 8 2 4 12 12 12 0 Ferredoxin thioredoxin reductase variable alpha chain DUF727 PF05303.7 CCM05265.1 - 0.00013 21.7 7.0 32 4.3 0.0 8.2 9 0 0 9 9 9 0 Protein of unknown function (DUF727) Me-amine-dh_H PF06433.6 CCM05265.1 - 0.00089 17.9 0.0 4.3 5.8 0.0 4.0 3 1 1 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) PQQ PF01011.16 CCM05265.1 - 0.0011 18.3 0.0 10 5.8 0.0 6.0 7 0 0 7 7 7 0 PQQ enzyme repeat NB-ARC PF00931.17 CCM05265.1 - 0.0026 16.6 0.0 0.005 15.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Peptidase_S9_N PF02897.10 CCM05265.1 - 0.0073 14.9 1.9 45 2.4 0.0 5.6 4 3 2 7 7 7 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Cytochrom_D1 PF02239.11 CCM05265.1 - 0.11 10.7 14.7 0.13 10.5 0.4 4.9 4 1 1 5 5 5 0 Cytochrome D1 heme domain MFS_1 PF07690.11 CCM05266.1 - 2.1e-20 72.7 18.8 3.2e-20 72.1 13.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily WSC PF01822.14 CCM05267.1 - 1.4e-27 95.3 19.8 1.8e-14 53.4 6.1 2.1 2 0 0 2 2 2 2 WSC domain PAN_3 PF08277.7 CCM05267.1 - 5.7 6.6 8.2 2.1 8.0 0.8 2.5 2 0 0 2 2 2 0 PAN-like domain DUF3486 PF11985.3 CCM05268.1 - 0.016 15.2 0.3 0.025 14.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) MxiH PF09392.5 CCM05268.1 - 0.028 14.9 0.1 0.4 11.2 0.1 2.3 1 1 0 1 1 1 0 Type III secretion needle MxiH like DUF3294 PF07957.6 CCM05268.1 - 0.03 13.8 0.3 1.9 7.9 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3294) FlaC_arch PF05377.6 CCM05268.1 - 0.053 13.4 0.1 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FliT PF05400.8 CCM05268.1 - 0.1 13.0 2.1 0.2 12.0 0.5 2.2 3 1 0 3 3 3 0 Flagellar protein FliT ERG4_ERG24 PF01222.12 CCM05269.1 - 2e-06 26.6 0.0 2.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 CCM05269.1 - 0.00059 19.9 0.1 0.002 18.2 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM05269.1 - 0.064 13.3 0.2 0.92 9.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipid methyltransferase DUF3446 PF11928.3 CCM05271.1 - 5.9 7.1 12.3 5.5 7.2 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) WD40 PF00400.27 CCM05272.1 - 1.6e-80 262.3 11.2 1.8e-11 43.4 0.0 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 CCM05272.1 - 9.3e-12 45.0 0.0 0.00027 20.7 0.0 3.4 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 CCM05272.1 - 7.1e-06 25.6 7.2 0.13 11.6 0.2 3.8 1 1 2 3 3 3 3 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 CCM05272.1 - 7.2e-05 22.3 2.1 30 4.4 0.0 5.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 CCM05272.1 - 0.00021 19.5 1.2 0.022 12.9 0.0 3.8 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCM05272.1 - 0.0023 16.2 0.1 1.1 7.5 0.0 3.5 2 1 2 4 4 4 2 Cytochrome D1 heme domain Nbas_N PF15492.1 CCM05272.1 - 0.02 14.0 1.0 10 5.0 0.0 3.8 2 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 CCM05272.1 - 0.024 13.9 3.7 45 3.4 0.1 5.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature TruB_C PF09142.6 CCM05272.1 - 0.56 9.8 8.6 1.1 8.9 0.1 3.7 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Ras PF00071.17 CCM05273.1 - 3.8e-14 52.3 0.1 5.9e-09 35.5 0.0 2.1 1 1 1 2 2 2 2 Ras family GCV_T PF01571.16 CCM05273.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Cys_Met_Meta_PP PF01053.15 CCM05275.1 - 2.3e-128 427.7 0.0 8.4e-128 425.9 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCM05275.1 - 9.6e-11 41.3 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CCM05275.1 - 2.4e-09 36.4 0.0 3.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCM05275.1 - 7.2e-09 35.0 0.0 1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCM05275.1 - 0.02 14.0 0.0 0.26 10.3 0.0 2.6 1 1 0 1 1 1 0 Beta-eliminating lyase GDC-P PF02347.11 CCM05275.1 - 0.043 12.5 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein HET PF06985.6 CCM05276.1 - 2.4e-18 66.6 4.3 1.1e-14 54.7 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Peptidase_S9 PF00326.16 CCM05277.1 - 8.4e-37 126.4 0.0 1.5e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCM05277.1 - 2.9e-09 36.8 0.0 7.7e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCM05277.1 - 0.00019 21.4 0.1 0.00094 19.1 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CCM05277.1 - 0.00085 17.9 0.1 0.013 14.0 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 CCM05277.1 - 0.011 15.0 0.1 0.037 13.2 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.8 CCM05277.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 CCM05277.1 - 0.12 11.9 0.3 0.34 10.4 0.2 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 CCM05278.1 - 6.4e-29 100.7 50.3 1.8e-27 96.0 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 CCM05278.1 - 3.4 7.8 10.6 6.4 6.9 0.0 3.2 3 1 0 3 3 3 0 NfeD-like C-terminal, partner-binding zf-C2H2_jaz PF12171.3 CCM05279.1 - 1.1e-08 34.9 16.9 2.7e-07 30.5 0.0 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CCM05279.1 - 0.00085 19.5 38.1 0.16 12.3 0.2 6.8 6 1 1 7 7 7 3 Zinc finger, C2H2 type zf-met PF12874.2 CCM05279.1 - 0.00086 19.4 0.3 0.00086 19.4 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CCM05279.1 - 0.0066 16.7 34.0 0.065 13.6 0.2 5.8 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCM05279.1 - 0.016 15.0 0.1 0.016 15.0 0.0 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCM05279.1 - 0.037 14.1 0.5 0.037 14.1 0.4 4.1 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 CCM05279.1 - 0.16 12.2 18.1 11 6.5 1.0 5.6 5 0 0 5 5 5 0 Zinc-finger double domain AKAP95 PF04988.7 CCM05279.1 - 0.17 11.6 4.5 2.2 8.0 0.1 2.7 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 CCM05280.1 - 3.2e-06 27.1 4.2 0.031 14.5 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM05280.1 - 0.00019 21.5 4.6 0.26 11.7 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCM05280.1 - 0.0023 18.0 0.8 0.018 15.1 0.1 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CCM05280.1 - 0.031 14.4 1.2 0.054 13.6 0.4 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM05280.1 - 0.07 13.3 0.4 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCM05280.1 - 0.15 11.9 0.6 0.15 11.9 0.4 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM05281.1 - 0.00013 22.0 7.1 0.071 13.4 1.1 3.2 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CCM05281.1 - 0.016 15.3 2.9 0.033 14.2 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CCM05281.1 - 0.019 15.2 9.0 0.12 12.7 1.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.7 CCM05281.1 - 0.17 11.7 2.0 0.23 11.2 0.3 2.0 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_6 PF13912.1 CCM05281.1 - 2.8 7.9 6.1 0.75 9.7 0.9 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CCM05282.1 - 5.4e-08 32.6 14.5 0.22 11.9 0.1 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCM05282.1 - 1.6e-07 31.2 5.1 0.0013 18.8 1.5 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCM05282.1 - 1.9e-07 31.0 8.1 0.00098 19.2 0.8 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CCM05282.1 - 5.9e-06 26.3 18.1 0.5 10.8 0.2 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CCM05282.1 - 0.0001 22.3 4.3 0.089 12.9 0.0 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CCM05282.1 - 0.00017 21.3 14.0 1.1 9.2 0.2 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-DBF PF07535.7 CCM05282.1 - 2.6 7.7 4.9 6.8 6.4 0.5 2.5 2 0 0 2 2 2 0 DBF zinc finger zf-H2C2_2 PF13465.1 CCM05282.1 - 9.7 6.6 13.5 5.6 7.4 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger double domain Pkinase PF00069.20 CCM05283.1 - 1.9e-36 125.5 0.0 7.1e-18 64.6 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05283.1 - 0.00013 21.1 0.0 0.35 9.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Tyr-DNA_phospho PF06087.7 CCM05286.1 - 1.9e-54 185.0 0.0 3.2e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DUF1620 PF07774.8 CCM05286.1 - 2.3e-45 154.5 0.0 9.9e-45 152.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CCM05286.1 - 1.5e-12 47.5 1.8 3.3e-06 26.7 0.1 4.1 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 CCM05286.1 - 2.4e-09 36.2 0.3 0.038 13.5 0.0 4.8 4 0 0 4 4 4 2 PQQ enzyme repeat PLDc_2 PF13091.1 CCM05286.1 - 0.00048 19.8 0.0 0.5 10.1 0.0 3.6 2 1 0 2 2 2 1 PLD-like domain UIM PF02809.15 CCM05286.1 - 0.28 10.8 9.8 1.1 8.9 0.5 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif His_Phos_2 PF00328.17 CCM05287.1 - 2.1e-16 60.1 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RNB PF00773.14 CCM05288.1 - 6.7e-61 206.3 0.0 7.8e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 RNB domain Viral_helicase1 PF01443.13 CCM05289.1 - 0.038 13.5 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RXT2_N PF08595.6 CCM05289.1 - 0.05 13.4 0.1 0.061 13.1 0.1 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Myc_N PF01056.13 CCM05289.1 - 1.2 8.2 5.2 0.21 10.7 1.2 1.5 2 0 0 2 2 2 0 Myc amino-terminal region DUF2890 PF11081.3 CCM05289.1 - 3.9 7.4 7.9 5.6 6.9 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Med8 PF10232.4 CCM05291.1 - 0.017 14.6 7.1 0.031 13.8 4.4 1.8 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 FeoC PF09012.5 CCM05291.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator DUF904 PF06005.7 CCM05291.1 - 0.18 12.1 2.7 1.1 9.6 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF904) HMG_box PF00505.14 CCM05292.1 - 1.7e-15 57.0 5.9 2e-07 31.1 1.3 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM05292.1 - 1.7e-14 53.9 2.2 5.4e-06 26.6 1.1 2.7 2 0 0 2 2 2 2 HMG-box domain SUKH-4 PF14435.1 CCM05292.1 - 0.015 15.0 0.2 0.043 13.5 0.0 1.8 2 0 0 2 2 2 0 SUKH-4 immunity protein DUF1289 PF06945.8 CCM05292.1 - 0.069 12.6 1.7 8.4 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Catalase-rel PF06628.7 CCM05292.1 - 0.077 12.8 0.6 21 5.0 0.1 3.0 2 1 0 2 2 2 0 Catalase-related immune-responsive YABBY PF04690.8 CCM05292.1 - 1.5 9.0 6.3 0.38 10.9 0.7 2.0 1 1 1 2 2 2 0 YABBY protein RGS PF00615.14 CCM05293.1 - 4.4e-10 39.6 0.9 9.8e-05 22.4 0.1 2.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain Solute_trans_a PF03619.11 CCM05294.1 - 1.9e-98 329.1 8.1 2.6e-98 328.7 5.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Barttin PF15462.1 CCM05294.1 - 0.72 9.4 3.5 1.2 8.7 2.4 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Pex19 PF04614.7 CCM05295.1 - 8.1e-57 192.6 6.3 1.3e-56 191.9 4.4 1.3 1 0 0 1 1 1 1 Pex19 protein family MRP-S27 PF10037.4 CCM05295.1 - 0.012 14.5 1.2 0.012 14.5 0.8 1.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 UCH PF00443.24 CCM05295.1 - 0.31 10.1 2.2 0.56 9.2 1.4 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase IATP PF04568.7 CCM05295.1 - 0.68 10.0 5.6 0.19 11.8 1.0 2.0 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Mito_carr PF00153.22 CCM05296.1 - 5.5e-55 183.0 0.5 5.5e-18 64.4 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein RNase_P_p30 PF01876.11 CCM05297.1 - 3e-28 97.9 0.0 5.6e-28 97.0 0.0 1.4 2 0 0 2 2 2 1 RNase P subunit p30 Fungal_trans PF04082.13 CCM05299.1 - 4.7e-25 87.9 0.0 7.7e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM05299.1 - 3.8e-10 39.5 11.5 8.1e-10 38.4 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.18 CCM05300.1 - 7.6e-29 100.9 0.0 3.9e-14 52.6 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM05300.1 - 0.025 14.5 0.8 0.18 11.7 0.6 2.1 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCM05300.1 - 0.12 12.9 0.2 1.4 9.5 0.1 2.7 2 1 0 2 2 2 0 Aspartyl protease Sigma_1s PF02454.11 CCM05300.1 - 0.21 11.3 0.3 0.38 10.5 0.2 1.3 1 0 0 1 1 1 0 Sigma 1s protein HAD PF12710.2 CCM05301.1 - 6.6e-15 55.7 0.0 3.1e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCM05301.1 - 1.8e-14 54.6 1.5 1.4e-12 48.5 1.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCM05301.1 - 2.1e-14 53.1 0.1 2.1e-14 53.1 0.1 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CCM05301.1 - 2.2e-12 46.7 0.0 4.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCM05301.1 - 0.00037 20.1 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCM05301.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SGL PF08450.7 CCM05302.1 - 4.2e-32 111.4 0.0 1.2e-31 109.9 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CCM05302.1 - 1.2e-05 25.2 0.0 0.00028 20.8 0.0 3.1 3 1 0 3 3 3 1 Strictosidine synthase Arylesterase PF01731.15 CCM05302.1 - 0.00055 19.8 0.0 0.0099 15.8 0.0 2.4 1 1 1 2 2 2 1 Arylesterase PD40 PF07676.7 CCM05302.1 - 0.028 14.0 4.3 3.1 7.5 0.2 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat NHL PF01436.16 CCM05302.1 - 0.081 12.9 2.3 4.1 7.5 0.0 3.2 3 0 0 3 3 3 0 NHL repeat F-box-like PF12937.2 CCM05303.1 - 5.2e-09 35.7 0.0 1.3e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like RepB-RCR_reg PF10723.4 CCM05303.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Replication regulatory protein RepB CDKN3 PF05706.7 CCM05304.1 - 3.7e-05 23.2 0.2 5.2e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.15 CCM05304.1 - 4.4e-05 23.0 0.0 7.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCM05304.1 - 0.00039 19.8 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCM05304.1 - 0.00072 19.6 0.1 0.0027 17.7 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CCM05304.1 - 0.0018 18.5 0.3 0.11 12.7 0.2 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Rhv PF00073.15 CCM05305.1 - 0.12 12.0 0.0 0.87 9.2 0.0 2.0 1 1 0 1 1 1 0 picornavirus capsid protein Pkinase PF00069.20 CCM05307.1 - 1.5e-60 204.5 0.0 1.9e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05307.1 - 2.9e-26 92.1 0.0 3.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM05307.1 - 1.2e-05 24.4 0.0 7.4e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCM05307.1 - 0.0062 16.2 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCM05307.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C14 PF00656.17 CCM05308.1 - 2.1e-62 211.0 0.2 2.9e-62 210.6 0.1 1.1 1 0 0 1 1 1 1 Caspase domain DUF4038 PF13204.1 CCM05308.1 - 0.029 13.7 0.2 0.068 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4038) PBP PF01161.15 CCM05312.1 - 1.4e-19 70.4 0.0 1.6e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF2984 PF11203.3 CCM05313.1 - 0.062 13.4 0.1 0.12 12.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2984) Pkinase PF00069.20 CCM05314.1 - 1.6e-62 211.0 0.0 6.2e-34 117.3 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05314.1 - 2.1e-31 108.9 0.0 3.6e-15 55.7 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 CCM05314.1 - 1.1e-23 83.7 3.4 2.7e-23 82.5 0.0 2.4 2 1 0 2 2 2 1 Anticodon binding domain of tRNAs RWD PF05773.17 CCM05314.1 - 1.4e-14 53.8 0.1 3.8e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 CCM05314.1 - 6.8e-13 48.3 0.3 2.1e-12 46.7 0.0 2.0 2 1 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 CCM05314.1 - 0.00015 21.5 0.1 0.002 17.9 0.0 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCM05314.1 - 0.013 14.5 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Methyltransf_16 PF10294.4 CCM05316.1 - 1.1e-16 60.7 0.0 8.5e-16 57.8 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCM05316.1 - 3.5e-08 34.0 0.0 7.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM05316.1 - 0.00034 21.0 0.0 0.00099 19.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM05316.1 - 0.00053 20.0 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM05316.1 - 0.0012 18.4 0.0 0.0034 16.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CCM05316.1 - 0.0076 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CCM05316.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.1 CCM05316.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CCM05316.1 - 0.025 15.0 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CCM05316.1 - 0.095 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_L7Ae PF01248.21 CCM05318.1 - 7.2e-22 76.7 0.5 1.2e-21 76.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cupin_8 PF13621.1 CCM05320.1 - 1.2e-20 74.0 0.0 2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CCM05320.1 - 1e-18 67.6 0.2 1.7e-18 66.8 0.2 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase 4HBT PF03061.17 CCM05321.1 - 5.6e-09 35.9 0.0 9.2e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily ERCC4 PF02732.10 CCM05322.1 - 1.1e-27 96.5 0.0 2.2e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain FTCD_C PF04961.7 CCM05322.1 - 0.031 13.6 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Acyltransferase PF01553.16 CCM05324.1 - 6.4e-09 35.3 0.0 2.7e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase F-box-like PF12937.2 CCM05325.1 - 0.012 15.3 0.5 0.034 13.8 0.3 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 CCM05325.1 - 0.062 12.9 0.0 1.9 8.2 0.0 2.7 2 0 0 2 2 2 0 F-box domain HET PF06985.6 CCM05326.1 - 2.1e-24 86.2 0.0 4.1e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 CCM05330.1 - 0.00014 21.5 0.8 0.00031 20.4 0.6 1.7 1 0 0 1 1 1 1 F-box-like PIG-X PF08320.7 CCM05331.1 - 3.3e-26 91.8 0.0 4.2e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 6PF2K PF01591.13 CCM05332.1 - 5.5e-73 244.7 0.1 7.7e-73 244.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCM05332.1 - 1.8e-32 112.6 0.0 3.1e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCM05332.1 - 1.9e-07 31.0 0.1 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCM05332.1 - 0.00019 22.2 0.2 0.00076 20.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCM05332.1 - 0.014 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin GBP PF02263.14 CCM05332.1 - 0.057 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Methyltransf_32 PF13679.1 CCM05332.1 - 0.13 11.8 0.1 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Glyco_transf_8 PF01501.15 CCM05333.1 - 3.5e-05 23.2 0.0 8.3e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF1627 PF07789.7 CCM05333.1 - 0.026 14.0 0.1 0.076 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) Peptidase_M1 PF01433.15 CCM05334.1 - 4.8e-52 177.3 0.0 5.7e-25 88.2 0.0 3.4 2 1 1 3 3 3 3 Peptidase family M1 ERAP1_C PF11838.3 CCM05334.1 - 1e-51 176.1 0.2 1.6e-51 175.5 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Aldo_ket_red PF00248.16 CCM05335.1 - 8.8e-57 192.0 0.0 1.2e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3602 PF12223.3 CCM05340.1 - 2.5e-17 63.0 30.0 4.2e-05 23.8 1.4 4.7 2 1 3 5 5 5 4 Protein of unknown function (DUF3602) IBR PF01485.16 CCM05342.1 - 3.9e-13 49.0 32.7 7.7e-09 35.3 3.7 3.7 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 CCM05342.1 - 6.3e-06 26.1 4.4 6.3e-06 26.1 3.1 4.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM05342.1 - 2.6e-05 23.9 5.8 2.6e-05 23.9 4.0 3.9 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Caldesmon PF02029.10 CCM05342.1 - 5.6e-05 21.7 7.1 8.9e-05 21.1 4.9 1.2 1 0 0 1 1 1 1 Caldesmon zf-C3HC4 PF00097.20 CCM05342.1 - 0.00011 21.7 4.3 0.00011 21.7 3.0 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCM05342.1 - 0.00039 20.0 3.5 0.00039 20.0 2.4 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 CCM05342.1 - 0.0006 19.5 6.5 0.0006 19.5 4.5 4.0 2 1 1 3 3 3 1 Ring finger domain IBR PF01485.16 CCM05343.1 - 3.7e-15 55.5 28.8 5.9e-09 35.6 4.4 3.8 3 0 0 3 3 3 2 IBR domain zf-CCCH PF00642.19 CCM05343.1 - 4.1e-12 45.4 15.9 6.7e-06 25.6 4.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 CCM05343.1 - 8.3e-06 25.7 3.6 8.3e-06 25.7 2.5 4.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM05343.1 - 2.2e-05 24.2 5.5 2.2e-05 24.2 3.8 3.9 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CCM05343.1 - 4.7e-05 23.1 5.4 4.7e-05 23.1 3.8 3.8 2 1 1 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CCM05343.1 - 0.00017 21.2 2.7 0.00017 21.2 1.9 2.2 2 0 0 2 2 1 1 RING-type zinc-finger RRM_1 PF00076.17 CCM05343.1 - 0.00045 19.7 0.1 0.15 11.7 0.0 3.7 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM05343.1 - 0.0029 17.5 0.1 2.9 7.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CCM05343.1 - 0.0061 16.2 4.5 0.0061 16.2 3.1 3.9 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM05343.1 - 0.0096 15.6 4.9 0.0096 15.6 3.4 3.8 2 1 1 3 3 1 1 zinc-RING finger domain zf-CCCH_2 PF14608.1 CCM05343.1 - 4.6 7.4 22.2 0.031 14.2 3.0 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type MFS_1 PF07690.11 CCM05345.1 - 7.4e-11 41.3 23.6 7e-06 24.9 1.7 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sulfate_tra_GLY PF13792.1 CCM05345.1 - 0.23 11.1 3.6 5.2 6.8 0.5 2.9 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif MFS_1 PF07690.11 CCM05346.1 - 1.2e-12 47.2 21.2 1.2e-12 47.2 14.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2781 PF10914.3 CCM05346.1 - 0.64 9.7 4.2 0.67 9.7 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2781) Pkinase PF00069.20 CCM05348.1 - 5.4e-14 51.9 0.2 1e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05348.1 - 1.2e-08 34.3 0.1 5.9e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCM05348.1 - 0.0022 17.7 0.2 0.027 14.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCM05348.1 - 0.0056 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CCM05348.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 CCM05348.1 - 0.021 13.9 0.1 0.037 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SLAC1 PF03595.12 CCM05349.1 - 1.9e-66 223.9 51.3 2.1e-66 223.8 35.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Ammonium_transp PF00909.16 CCM05350.1 - 1.4e-116 389.2 31.1 1.6e-116 389.0 21.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Abhydrolase_3 PF07859.8 CCM05351.1 - 5.2e-65 218.9 0.0 6.2e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CCM05351.1 - 3.6e-10 39.1 0.1 7.9e-10 38.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 CCM05351.1 - 2.8e-06 26.2 0.0 3.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCM05351.1 - 0.00049 19.8 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CCM05351.1 - 0.0017 17.2 0.0 0.0023 16.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 CCM05351.1 - 0.0027 16.5 0.0 0.0036 16.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.16 CCM05351.1 - 0.008 15.4 0.0 0.52 9.4 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Snurportin1 PF11538.3 CCM05353.1 - 0.0016 18.1 1.3 0.0037 17.0 0.9 1.6 1 0 0 1 1 1 1 Snurportin1 DUF563 PF04577.9 CCM05354.1 - 4.1e-19 69.3 0.5 6.3e-18 65.4 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF563) Methyltransf_16 PF10294.4 CCM05355.1 - 8.4e-18 64.4 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCM05355.1 - 0.0015 19.0 0.0 0.0024 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 CCM05355.1 - 0.0063 15.6 0.0 0.0092 15.1 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.9 CCM05355.1 - 0.0081 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CCM05355.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3280 PF11684.3 CCM05356.1 - 0.00097 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) zf-MYND PF01753.13 CCM05356.1 - 0.066 13.1 5.6 0.12 12.2 3.9 1.4 1 0 0 1 1 1 0 MYND finger PRP3 PF08572.5 CCM05357.1 - 5e-65 219.0 5.9 8.1e-65 218.3 4.1 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CCM05357.1 - 6.5e-33 113.1 0.8 1.8e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Ribosomal_L16 PF00252.13 CCM05359.1 - 6e-39 132.8 0.4 7.1e-39 132.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DCP1 PF06058.8 CCM05360.1 - 1.3e-17 63.9 0.1 3e-17 62.8 0.0 1.5 2 0 0 2 2 2 1 Dcp1-like decapping family NP1-WLL PF11733.3 CCM05362.1 - 1.7 8.9 6.9 21 5.4 1.1 2.8 2 0 0 2 2 2 0 Non-capsid protein NP1 Josephin PF02099.12 CCM05363.1 - 1e-40 138.9 0.1 1.6e-40 138.3 0.1 1.2 1 0 0 1 1 1 1 Josephin ATG27 PF09451.5 CCM05364.1 - 4.4e-47 160.5 0.0 5.6e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 CCM05364.1 - 0.00022 20.3 0.0 0.00034 19.7 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Aldo_ket_red PF00248.16 CCM05366.1 - 5e-66 222.4 0.0 5.7e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 CCM05367.1 - 1.1e-63 215.3 0.0 3.2e-54 184.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HSP9_HSP12 PF04119.7 CCM05368.1 - 2.5e-20 72.3 5.1 2.5e-20 72.3 3.5 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 MOFRL PF05161.8 CCM05368.1 - 0.1 12.7 2.2 1.3 9.1 0.5 2.0 1 1 1 2 2 2 0 MOFRL family zf-RING_2 PF13639.1 CCM05369.1 - 6.2e-13 48.3 9.2 9.5e-13 47.7 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 CCM05369.1 - 1.4e-06 28.0 2.6 3.5e-06 26.7 1.8 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCM05369.1 - 1.4e-06 28.3 3.4 2.5e-06 27.5 2.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 CCM05369.1 - 4.6e-05 22.9 5.7 6.8e-05 22.3 4.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CCM05369.1 - 4.8e-05 23.3 8.1 7.9e-05 22.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCM05369.1 - 6.6e-05 22.4 3.5 0.00011 21.7 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCM05369.1 - 0.00039 20.0 6.4 0.0006 19.4 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM05369.1 - 0.00081 19.0 5.9 0.0012 18.4 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 CCM05369.1 - 0.07 13.1 4.8 0.16 11.9 3.3 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CCM05369.1 - 0.77 9.8 6.8 1.3 9.1 4.7 1.4 1 0 0 1 1 1 0 RING-variant domain p450 PF00067.17 CCM05371.1 - 2e-62 211.2 0.0 4.9e-62 209.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM05372.1 - 1.1e-68 231.8 0.0 2.3e-68 230.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM05373.1 - 1.1e-65 221.9 0.0 2.1e-65 221.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Herpes_UL36 PF03586.8 CCM05373.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Sec10 PF07393.6 CCM05375.1 - 5.5e-134 447.9 0.0 7.4e-134 447.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 CCM05375.1 - 0.00018 21.1 0.3 0.00057 19.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM05375.1 - 0.0022 17.6 0.1 0.005 16.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain ECM11 PF15463.1 CCM05377.1 - 0.083 13.1 0.0 0.083 13.1 0.0 2.4 3 0 0 3 3 3 0 Extracellular mutant protein 11 4HBT PF03061.17 CCM05378.1 - 5.8e-09 35.9 0.0 9.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 CCM05378.1 - 4.2e-06 27.2 0.0 5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 CCM05378.1 - 0.0022 16.9 0.5 0.0091 14.9 0.7 1.7 2 0 0 2 2 2 1 Acyl-ACP thioesterase ECH PF00378.15 CCM05379.1 - 1.8e-72 243.3 0.4 2.3e-72 243.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CCM05379.1 - 1.1e-05 25.2 0.2 0.00099 18.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 ECH_C PF13766.1 CCM05379.1 - 0.00021 21.3 0.1 0.0084 16.2 0.1 2.3 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region WD40 PF00400.27 CCM05380.1 - 1e-29 101.3 9.5 1.1e-07 31.4 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCM05380.1 - 0.0065 15.2 0.5 0.014 14.1 0.0 1.7 2 0 0 2 2 2 1 Nup133 N terminal like Nha1_C PF08619.5 CCM05380.1 - 0.1 11.8 5.5 0.19 10.9 3.8 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Copper-fist PF00649.13 CCM05381.1 - 1e-20 72.6 0.9 2.4e-20 71.4 0.6 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain zf-UBR PF02207.15 CCM05381.1 - 3.5 7.4 12.5 1.5 8.5 1.1 2.6 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Aminotran_1_2 PF00155.16 CCM05382.1 - 1.1e-35 123.2 0.0 2.4e-35 122.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCM05382.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3651 PF12371.3 CCM05382.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3651) DUF775 PF05603.7 CCM05383.1 - 2.2e-35 122.0 0.0 2.8e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) PQ-loop PF04193.9 CCM05384.1 - 5.7e-10 38.5 0.6 5.7e-10 38.5 0.4 1.9 2 0 0 2 2 2 1 PQ loop repeat ATP-synt_8 PF00895.15 CCM05384.1 - 0.28 11.4 5.9 0.53 10.5 3.5 2.0 1 1 0 1 1 1 0 ATP synthase protein 8 DUF485 PF04341.7 CCM05384.1 - 9.4 6.0 7.6 6.7 6.4 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Adap_comp_sub PF00928.16 CCM05385.1 - 3e-70 236.3 0.0 4.7e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Dus PF01207.12 CCM05385.1 - 2.2e-50 171.2 0.0 6.4e-50 169.7 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Clat_adaptor_s PF01217.15 CCM05385.1 - 9.3e-07 28.6 0.6 1.5e-06 27.9 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-CCCH PF00642.19 CCM05385.1 - 0.00012 21.6 5.3 0.14 11.8 0.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mon1 PF03164.9 CCM05385.1 - 0.14 10.7 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 HMGL-like PF00682.14 CCM05386.1 - 8.4e-42 143.4 0.6 2.5e-41 141.9 0.4 1.7 1 1 0 1 1 1 1 HMGL-like DUF4536 PF15055.1 CCM05387.1 - 0.00012 22.0 1.0 0.00012 22.0 0.7 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) Fungal_trans PF04082.13 CCM05389.1 - 1.1e-36 126.0 0.0 3.4e-36 124.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM05389.1 - 5.3e-07 29.4 13.5 8.7e-07 28.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.1 CCM05391.1 - 4.4e-22 77.9 3.8 6.9e-22 77.3 2.7 1.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Nucleoplasmin PF03066.10 CCM05392.1 - 0.087 12.3 2.9 0.077 12.5 2.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 CCM05392.1 - 0.15 12.3 4.2 0.15 12.3 2.9 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 CCM05392.1 - 0.56 9.7 4.6 0.52 9.9 3.2 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region TFIIE-A_C-term PF11521.3 CCM05392.1 - 0.57 10.1 4.8 0.67 9.9 3.3 1.2 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DUF4611 PF15387.1 CCM05392.1 - 1.5 9.0 4.4 1.8 8.7 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SUZ PF12752.2 CCM05393.1 - 2.7e-11 43.8 1.1 2.7e-11 43.8 0.7 2.7 1 1 1 2 2 2 1 SUZ domain SPATIAL PF15256.1 CCM05393.1 - 0.16 12.0 0.5 0.19 11.7 0.3 1.1 1 0 0 1 1 1 0 SPATIAL Aminotran_1_2 PF00155.16 CCM05394.1 - 3.5e-52 177.5 0.0 1.8e-44 152.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.15 CCM05394.1 - 2.5e-05 23.0 0.0 5.7e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 CCM05394.1 - 0.0041 16.3 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCM05394.1 - 0.0043 15.8 0.0 0.0083 14.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF4080 PF13311.1 CCM05394.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) UDPG_MGDP_dh_N PF03721.9 CCM05395.1 - 4.7e-56 189.0 0.0 8.2e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 CCM05395.1 - 1.5e-35 121.5 0.1 7.7e-34 116.0 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 CCM05395.1 - 1.7e-31 108.2 0.0 3.4e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_7 PF13241.1 CCM05395.1 - 0.0023 18.1 1.0 0.087 13.0 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 CCM05395.1 - 0.0034 17.1 0.1 0.11 12.1 0.0 2.6 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 CCM05395.1 - 0.024 15.0 0.6 4.5 7.7 0.0 3.2 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent HET PF06985.6 CCM05396.1 - 1.9e-17 63.7 0.0 3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Striatin PF08232.7 CCM05397.1 - 0.067 13.5 1.7 0.24 11.6 1.2 1.9 1 0 0 1 1 1 0 Striatin family DUF4436 PF14494.1 CCM05398.1 - 2.9e-10 39.8 0.8 5.1e-10 39.0 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Proteasome PF00227.21 CCM05399.1 - 3e-37 127.7 0.0 3.4e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 CCM05400.1 - 3.5e-24 83.7 20.0 8.5e-08 31.8 0.0 6.5 5 1 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CCM05400.1 - 1.4e-05 24.9 0.1 0.0056 16.4 0.0 3.2 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Pro-kuma_activ PF09286.6 CCM05401.1 - 2.2e-43 147.7 0.0 1e-42 145.5 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM05401.1 - 2.1e-05 23.8 2.3 3.1e-05 23.2 1.6 1.2 1 0 0 1 1 1 1 Subtilase family Vma12 PF11712.3 CCM05402.1 - 2.2e-11 43.6 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4231 PF14015.1 CCM05402.1 - 0.044 13.7 0.9 0.083 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) TauE PF01925.14 CCM05402.1 - 0.066 12.6 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Atx10homo_assoc PF09759.4 CCM05403.1 - 6.6e-25 86.8 0.1 1.3e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 CCM05403.1 - 0.0058 16.4 0.1 0.022 14.5 0.0 2.1 1 1 0 1 1 1 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCM05403.1 - 0.069 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats LGT PF01790.13 CCM05403.1 - 0.081 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase Leo1 PF04004.8 CCM05404.1 - 2.3e-52 177.1 0.2 2.3e-52 177.1 0.1 2.0 2 0 0 2 2 2 1 Leo1-like protein TPR_11 PF13414.1 CCM05405.1 - 3.3e-17 61.8 6.5 2.1e-12 46.4 1.5 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCM05405.1 - 2.2e-07 30.2 3.9 0.09 12.4 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCM05405.1 - 1.9e-06 27.3 3.8 0.17 11.8 0.1 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCM05405.1 - 0.0014 18.5 3.3 0.046 13.6 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 CCM05405.1 - 0.002 17.9 0.3 0.002 17.9 0.2 2.3 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 CCM05405.1 - 0.0037 17.5 2.1 0.97 9.8 0.2 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCM05405.1 - 0.0099 16.5 5.1 0.7 10.6 1.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCM05405.1 - 0.031 14.0 0.3 5.1 7.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 CCM05405.1 - 0.042 13.9 0.6 9.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCM05405.1 - 0.047 14.1 1.6 0.82 10.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCM05405.1 - 0.07 12.9 0.8 5 7.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCM05405.1 - 0.26 12.0 6.6 14 6.6 0.1 4.0 4 1 1 5 5 4 0 Tetratricopeptide repeat FA_desaturase PF00487.19 CCM05407.1 - 1.6e-25 89.9 31.1 3.2e-25 89.0 21.5 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CCM05407.1 - 1.6e-06 28.1 0.0 4e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) DNA_pol_A_exo1 PF01612.15 CCM05408.1 - 3.7e-08 33.0 0.1 5.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.1 CCM05408.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DnaJ PF00226.26 CCM05409.1 - 4.1e-18 64.8 0.5 1.7e-17 62.8 0.3 2.1 1 0 0 1 1 1 1 DnaJ domain EST1_DNA_bind PF10373.4 CCM05411.1 - 4.4e-31 108.1 0.0 8.9e-31 107.1 0.0 1.5 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CCM05411.1 - 1.1e-13 51.3 0.0 2.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_12 PF13424.1 CCM05411.1 - 0.019 14.9 0.5 0.25 11.3 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCM05411.1 - 0.02 14.4 0.4 0.02 14.4 0.3 1.9 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 CCM05411.1 - 0.026 14.4 1.1 0.15 12.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCM05411.1 - 3.3 7.4 5.9 0.3 10.7 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SNF2_N PF00176.18 CCM05412.1 - 1e-74 251.0 0.2 1.4e-74 250.5 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM05412.1 - 2.7e-15 55.9 0.0 6.6e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM05412.1 - 4.2e-05 23.4 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 CCM05412.1 - 0.037 13.4 0.5 0.35 10.2 0.0 2.6 3 0 0 3 3 3 0 DEAD_2 zf-piccolo PF05715.8 CCM05412.1 - 0.12 12.4 2.5 0.26 11.3 1.7 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger TPT PF03151.11 CCM05413.1 - 1.1e-09 38.1 12.2 1.1e-09 38.1 8.5 2.7 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CCM05413.1 - 0.082 12.9 30.8 0.44 10.5 7.3 2.8 2 2 0 2 2 2 0 EamA-like transporter family Mre11_DNA_bind PF04152.9 CCM05414.1 - 2.1e-48 164.4 0.2 2.1e-48 164.4 0.2 2.2 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CCM05414.1 - 2.7e-22 79.1 0.8 4.2e-22 78.5 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCM05414.1 - 2.2e-05 24.3 0.1 0.00011 22.0 0.1 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain ArfGap PF01412.13 CCM05416.1 - 2.8e-21 75.4 0.1 3.9e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf IncA PF04156.9 CCM05417.1 - 0.06 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 IncA protein PAPS_reduct PF01507.14 CCM05418.1 - 2.1e-28 99.2 0.0 3e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RVT_3 PF13456.1 CCM05418.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like TPR_14 PF13428.1 CCM05419.1 - 1.4e-22 78.0 26.1 0.0017 18.7 0.0 12.3 5 2 8 13 13 12 6 Tetratricopeptide repeat HAT PF02184.11 CCM05419.1 - 7.5e-20 70.3 59.8 1.6e-08 34.0 2.1 13.6 14 2 0 14 14 13 5 HAT (Half-A-TPR) repeat TPR_2 PF07719.12 CCM05419.1 - 5.7e-14 50.8 1.8 0.2 11.6 0.0 8.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCM05419.1 - 9.9e-14 51.4 3.4 0.21 11.9 0.0 8.2 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCM05419.1 - 1.3e-12 47.9 20.3 7.5e-05 23.2 0.0 8.0 6 3 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 CCM05419.1 - 1.8e-09 37.0 4.0 0.031 13.9 0.0 6.6 5 2 2 7 7 7 1 TPR repeat TPR_12 PF13424.1 CCM05419.1 - 5.2e-08 32.7 7.3 0.13 12.2 0.0 6.7 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCM05419.1 - 1.2e-06 28.1 1.9 0.065 13.4 0.0 5.9 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCM05419.1 - 9.9e-06 24.8 20.9 0.32 10.0 0.5 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.1 CCM05419.1 - 3.3e-05 23.1 5.4 0.003 16.7 0.1 3.7 3 1 0 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 CCM05419.1 - 4.6e-05 22.9 14.5 1.5 8.8 0.0 8.1 10 1 1 11 11 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCM05419.1 - 4.7e-05 22.8 0.2 7.7 6.3 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCM05419.1 - 7.2e-05 22.9 9.7 24 5.6 0.2 7.9 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCM05419.1 - 0.00015 21.3 0.7 16 5.5 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CCM05419.1 - 0.00098 18.9 16.1 1.5 8.6 0.1 6.9 5 2 1 6 6 6 1 Mad3/BUB1 homology region 1 Fis1_TPR_C PF14853.1 CCM05419.1 - 0.0027 17.5 0.5 12 5.8 0.1 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.6 CCM05419.1 - 0.0081 15.8 20.5 0.058 13.1 0.5 6.7 5 3 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 c-SKI_SMAD_bind PF08782.5 CCM05419.1 - 0.25 11.4 5.0 24 5.1 0.1 4.9 5 0 0 5 5 5 0 c-SKI Smad4 binding domain RNA_pol_Rpc34 PF05158.7 CCM05420.1 - 2.5e-75 253.7 9.1 4.6e-64 216.6 1.6 2.3 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit Borrelia_P83 PF05262.6 CCM05420.1 - 6.2e-05 21.4 21.4 6.5e-05 21.4 14.9 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein DUF936 PF06075.7 CCM05420.1 - 0.54 9.1 33.5 0.84 8.4 23.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Herpes_DNAp_acc PF04929.7 CCM05420.1 - 0.6 9.0 0.0 0.6 9.0 0.0 3.0 1 1 2 3 3 3 0 Herpes DNA replication accessory factor MIP-T3 PF10243.4 CCM05420.1 - 1.6 7.1 68.1 2.7 6.3 47.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 CCM05420.1 - 1.8 6.9 39.7 2.8 6.3 27.5 1.2 1 0 0 1 1 1 0 Daxx Family MFS_1 PF07690.11 CCM05421.1 - 7.5e-20 70.9 65.9 6.5e-17 61.2 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BPL_N PF09825.4 CCM05422.1 - 4e-31 108.1 0.0 2.3e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CCM05422.1 - 1.7e-17 63.5 0.0 2.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DSRB PF10781.4 CCM05422.1 - 0.03 13.7 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Dextransucrase DSRB ABC_transp_aux PF09822.4 CCM05422.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system WBS_methylT PF12589.3 CCM05423.1 - 2 8.9 5.9 0.45 11.0 0.9 2.3 2 1 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome C2 PF00168.25 CCM05424.1 - 9.3e-25 86.3 0.0 6.9e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain Epimerase PF01370.16 CCM05426.1 - 8.2e-50 169.4 0.0 1.3e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CCM05426.1 - 3.1e-07 29.5 0.0 6.7e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CCM05426.1 - 2.4e-06 26.6 0.2 0.00081 18.3 0.1 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CCM05426.1 - 0.00083 18.1 0.0 0.0016 17.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CM1 PF03026.10 CCM05427.1 - 0.051 12.6 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M1 protein Semialdhyde_dh PF01118.19 CCM05427.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain eIF3_N PF09440.5 CCM05430.1 - 3.9e-26 91.7 1.2 9.6e-25 87.2 0.7 2.4 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 CCM05430.1 - 4.9e-09 36.4 0.1 1.9e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CCM05430.1 - 0.0092 15.7 0.1 0.031 14.0 0.1 1.9 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 CagZ PF09053.5 CCM05430.1 - 0.15 11.3 3.1 0.76 9.0 0.1 2.2 2 0 0 2 2 2 0 CagZ PQ-loop PF04193.9 CCM05431.1 - 9.7e-24 82.7 3.4 7.1e-11 41.4 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat TauE PF01925.14 CCM05431.1 - 0.16 11.4 11.4 1.6 8.1 0.4 2.2 1 1 0 2 2 2 0 Sulfite exporter TauE/SafE ox_reductase_C PF08635.5 CCM05432.1 - 3e-32 111.0 0.0 4.9e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 CCM05432.1 - 2.8e-14 53.6 0.0 4.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.20 CCM05434.1 - 2.6e-21 76.2 0.1 5.5e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM05434.1 - 2.1e-08 34.0 0.1 4.4e-08 33.0 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CCM05434.1 - 9e-06 25.6 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCM05434.1 - 0.00015 21.3 0.1 0.00087 18.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM05434.1 - 0.00033 20.6 0.1 0.00072 19.6 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 CCM05434.1 - 0.0064 16.5 0.1 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HECT PF00632.20 CCM05435.1 - 3.2e-93 312.3 0.0 4.8e-93 311.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 CCM05435.1 - 0.046 13.3 1.0 0.12 12.0 0.7 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF397 PF04149.7 CCM05435.1 - 0.13 11.8 0.1 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF397) Arginase PF00491.16 CCM05436.1 - 2.8e-69 233.5 0.4 9.9e-35 120.1 0.0 2.1 1 1 1 2 2 2 2 Arginase family MatE PF01554.13 CCM05437.1 - 2.7e-54 183.1 20.0 7.5e-29 100.4 4.9 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 CCM05437.1 - 6.4e-05 22.7 3.4 6.4e-05 22.7 2.3 4.2 3 2 2 5 5 5 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 CCM05438.1 - 6.4e-52 175.4 22.9 5.4e-30 104.1 6.3 2.5 2 0 0 2 2 2 2 MatE DUF4234 PF14018.1 CCM05438.1 - 0.035 13.8 0.9 11 5.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) Zip PF02535.17 CCM05440.1 - 3.3e-28 98.6 13.0 6.1e-28 97.7 8.9 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter UPF0016 PF01169.14 CCM05440.1 - 0.042 13.9 3.1 2.3 8.4 0.0 3.1 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 Fe-ADH PF00465.14 CCM05441.1 - 2.9e-57 193.9 2.2 3.8e-57 193.5 1.5 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CCM05441.1 - 1.8e-35 122.4 0.1 2.2e-35 122.1 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 CCM05441.1 - 3.4e-05 22.9 1.4 0.062 12.2 0.1 2.5 2 1 0 2 2 2 2 3-dehydroquinate synthase DUF3713 PF12506.3 CCM05442.1 - 0.06 13.4 0.3 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) ETF_alpha PF00766.14 CCM05443.1 - 5.4e-35 118.8 0.3 1e-34 117.9 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 CCM05443.1 - 9.2e-33 113.2 0.1 1.8e-32 112.3 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain FAD_binding_3 PF01494.14 CCM05444.1 - 6.4e-05 22.1 0.0 8.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NUC173 PF08161.7 CCM05445.1 - 8e-35 119.9 0.6 9.4e-33 113.2 0.0 2.9 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.17 CCM05445.1 - 0.026 14.5 0.7 4.9 7.5 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Acyltransferase PF01553.16 CCM05446.1 - 1.1e-12 47.5 0.0 3.5e-12 45.8 0.0 1.9 3 0 0 3 3 3 1 Acyltransferase Claudin_3 PF06653.6 CCM05447.1 - 0.0045 16.7 0.9 1.8 8.2 0.3 2.2 2 0 0 2 2 2 2 Tight junction protein, Claudin-like ABC2_membrane_2 PF12679.2 CCM05447.1 - 0.049 12.4 2.0 0.058 12.2 0.5 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2919 PF11143.3 CCM05447.1 - 0.1 12.4 3.2 0.072 12.9 0.8 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) 7TM-7TMR_HD PF07698.6 CCM05447.1 - 0.82 9.0 6.1 1.1 8.6 2.5 2.1 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase SUR7 PF06687.7 CCM05447.1 - 2.3 7.7 8.5 0.24 10.9 0.7 2.6 2 1 1 3 3 3 0 SUR7/PalI family Tetraspannin PF00335.15 CCM05447.1 - 2.5 7.3 8.6 5.6 6.1 2.7 2.4 2 1 0 2 2 2 0 Tetraspanin family Choline_transpo PF04515.7 CCM05448.1 - 3.3e-20 72.0 9.9 3.3e-20 72.0 6.9 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter PP2C PF00481.16 CCM05449.1 - 1.5e-66 224.4 0.1 6e-52 176.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 CCM05449.1 - 0.0037 16.9 0.4 0.032 13.9 0.2 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) W2 PF02020.13 CCM05450.1 - 2.9e-19 68.8 0.4 2.9e-19 68.8 0.3 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Fungal_trans PF04082.13 CCM05451.1 - 3e-08 32.8 0.0 4.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.28 CCM05452.1 - 0.017 14.7 0.4 0.031 13.9 0.3 1.4 1 0 0 1 1 1 0 F-box domain Mem_trans PF03547.13 CCM05453.1 - 8.5e-24 83.5 17.3 1.3e-12 46.7 0.1 2.0 2 0 0 2 2 2 2 Membrane transport protein NmrA PF05368.8 CCM05454.1 - 6.3e-18 64.8 0.0 1.4e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 CCM05454.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 CCM05454.1 - 0.0035 17.2 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 CCM05454.1 - 0.006 16.8 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 CCM05454.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_3 PF03447.11 CCM05454.1 - 0.063 13.6 0.1 0.72 10.2 0.0 2.2 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.8 CCM05455.1 - 7.9e-16 58.0 0.2 1.8e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 CCM05455.1 - 1.1e-05 25.6 0.1 0.00031 21.0 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 CCM05455.1 - 0.012 15.5 0.2 0.028 14.3 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 CCM05455.1 - 0.027 14.4 0.4 0.054 13.4 0.3 1.6 1 1 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 CCM05456.1 - 5.8e-51 173.4 0.0 7.3e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mnd1 PF03962.10 CCM05457.1 - 1.1e-46 158.8 0.0 2.1e-46 157.9 0.0 1.4 1 1 0 1 1 1 1 Mnd1 family Penicillinase_R PF03965.11 CCM05457.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Penicillinase repressor Oxidored_q6 PF01058.17 CCM05459.1 - 2e-22 79.1 0.1 3.1e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.20 CCM05460.1 - 6.6e-48 163.1 0.0 9e-34 116.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05460.1 - 4.4e-17 62.0 0.0 1.8e-16 60.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM05460.1 - 0.00018 21.3 0.0 0.00054 19.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCM05460.1 - 0.0005 19.1 0.0 0.00086 18.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCM05460.1 - 0.097 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CCM05460.1 - 0.1 12.1 0.1 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase HhH-GPD PF00730.20 CCM05461.1 - 1.6e-16 60.5 0.0 3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PLA2_B PF01735.13 CCM05463.1 - 2.9e-83 279.7 3.6 3.7e-83 279.3 2.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain zf-UBR PF02207.15 CCM05463.1 - 0.091 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) SecY PF00344.15 CCM05464.1 - 5.2e-97 324.8 11.5 6.6e-97 324.5 7.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CCM05464.1 - 1.7e-19 69.0 0.2 6e-19 67.2 0.1 2.0 2 0 0 2 2 2 1 Plug domain of Sec61p DUF4449 PF14613.1 CCM05466.1 - 2.9e-19 69.5 3.0 1.2e-18 67.5 0.0 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) AMP-binding PF00501.23 CCM05467.1 - 1.3e-87 293.9 0.0 1.5e-87 293.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCM05467.1 - 2.1e-13 51.0 0.1 1.2e-12 48.6 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CW_binding_2 PF04122.7 CCM05467.1 - 0.18 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 PLA2_B PF01735.13 CCM05468.1 - 3.5e-84 282.7 2.7 4.5e-84 282.3 1.9 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain zf-UBR PF02207.15 CCM05468.1 - 0.091 12.4 0.2 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) ThiF PF00899.16 CCM05469.1 - 8.4e-35 119.5 1.0 1.2e-34 119.0 0.2 1.6 2 0 0 2 2 2 1 ThiF family Saccharop_dh PF03435.13 CCM05469.1 - 0.00051 19.1 0.1 0.00092 18.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 CCM05469.1 - 0.0074 15.9 0.3 0.025 14.2 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CCM05469.1 - 0.015 15.5 0.1 0.041 14.1 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.19 CCM05469.1 - 0.069 12.0 0.7 0.13 11.1 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.11 CCM05470.1 - 7.7e-18 64.3 56.7 1.3e-17 63.5 35.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Arteri_Gl PF00951.13 CCM05470.1 - 0.16 11.5 4.5 0.1 12.1 1.0 2.0 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein DUF4234 PF14018.1 CCM05470.1 - 0.19 11.4 0.1 0.19 11.4 0.1 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4234) MFS_1_like PF12832.2 CCM05470.1 - 0.45 10.3 8.9 0.17 11.6 1.1 3.3 3 0 0 3 3 3 0 MFS_1 like family p450 PF00067.17 CCM05472.1 - 3.2e-66 223.7 0.0 4.4e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 CCM05473.1 - 1.6e-43 149.0 0.0 2e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM05473.1 - 1.7e-38 132.1 0.0 2.9e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Vps26 PF03643.10 CCM05475.1 - 4.1e-128 425.9 2.4 4.7e-128 425.7 1.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CCM05475.1 - 0.0013 18.6 1.3 1.8 8.3 0.0 3.8 2 1 2 5 5 5 2 Arrestin (or S-antigen), N-terminal domain CLN3 PF02487.12 CCM05476.1 - 8.8e-48 163.0 0.1 1.4e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 CLN3 protein AAA_5 PF07728.9 CCM05477.1 - 4.4e-65 217.6 0.0 7.9e-27 93.6 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCM05477.1 - 0.0032 17.4 1.0 0.035 14.0 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain VWA_2 PF13519.1 CCM05477.1 - 0.03 14.4 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_22 PF13401.1 CCM05477.1 - 0.048 13.8 0.0 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.26 CCM05478.1 - 3.9e-07 30.0 0.1 8e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCM05478.1 - 0.00042 20.3 1.6 0.0012 18.9 0.2 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain LXG PF04740.7 CCM05478.1 - 0.062 13.0 0.7 0.14 11.9 0.5 1.6 1 0 0 1 1 1 0 LXG domain of WXG superfamily TMEM237 PF15383.1 CCM05478.1 - 0.29 10.2 0.8 0.58 9.2 0.5 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 Aminotran_1_2 PF00155.16 CCM05479.1 - 3.3e-39 134.8 0.0 4e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 CCM05479.1 - 0.027 13.0 0.0 0.056 11.9 0.0 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 CCM05479.1 - 0.081 11.1 0.0 0.36 9.0 0.0 1.8 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme adh_short PF00106.20 CCM05480.1 - 8.7e-12 45.2 0.1 1.4e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CCM05480.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CCM05480.1 - 0.0041 16.7 0.1 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_4 PF04669.8 CCM05481.1 - 3.5e-15 55.8 1.7 2e-09 37.0 0.1 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis Cul7 PF11515.3 CCM05481.1 - 0.052 13.4 0.3 7.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 adh_short PF00106.20 CCM05482.1 - 1.4e-26 93.4 0.0 3.1e-26 92.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM05482.1 - 7.7e-19 68.4 0.1 1.5e-18 67.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM05482.1 - 3.7e-07 29.9 0.0 6.9e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 CCM05482.1 - 0.00017 20.7 0.2 0.00037 19.6 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 CCM05482.1 - 0.0036 17.0 0.7 0.039 13.7 0.3 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CCM05482.1 - 0.0047 16.3 0.1 0.5 9.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM05482.1 - 0.014 15.3 0.0 0.045 13.7 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 CCM05482.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CCM05482.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 CCM05482.1 - 0.048 13.7 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Transferrin PF00405.12 CCM05482.1 - 0.11 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Transferrin DUF3848 PF12959.2 CCM05483.1 - 0.032 14.1 0.1 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) RRF_GI PF12614.3 CCM05483.1 - 0.069 12.9 1.6 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Ribosome recycling factor ISG65-75 PF11727.3 CCM05483.1 - 2.8 6.9 8.7 0.58 9.1 0.1 2.8 3 0 0 3 3 3 0 Invariant surface glycoprotein Sel1 PF08238.7 CCM05485.1 - 3.8e-11 43.2 13.9 4.5e-05 23.9 0.1 5.1 5 0 0 5 5 5 4 Sel1 repeat TPR_11 PF13414.1 CCM05485.1 - 0.0036 16.9 1.0 0.0071 15.9 0.0 2.0 2 0 0 2 2 2 1 TPR repeat DUF294_C PF10335.4 CCM05485.1 - 0.013 15.1 0.3 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain TPR_1 PF00515.23 CCM05485.1 - 0.054 13.1 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCM05485.1 - 0.26 11.3 3.8 0.38 10.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.24 CCM05486.1 - 1.2e-44 151.7 0.0 7.1e-44 149.2 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCM05486.1 - 2.2e-25 87.9 0.1 4.6e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCM05486.1 - 3.2e-20 71.7 0.0 6.8e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM05486.1 - 0.013 15.3 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCM05486.1 - 0.039 13.9 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain TATR PF03430.8 CCM05487.1 - 0.32 9.5 4.9 0.43 9.1 3.4 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator EpuA PF11772.3 CCM05489.1 - 0.79 9.2 5.6 1.5 8.3 3.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta SPC12 PF06645.8 CCM05489.1 - 7.8 6.3 6.3 1.8 8.4 1.2 2.1 1 1 2 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 CCM05490.1 - 3.9e-25 88.3 27.5 3.9e-25 88.3 19.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TIMELESS PF04821.9 CCM05491.1 - 5.6e-57 193.0 0.1 5.6e-57 193.0 0.1 2.4 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.8 CCM05491.1 - 4.1e-12 45.8 0.1 4.1e-12 45.8 0.0 4.1 3 1 2 5 5 5 1 Timeless protein C terminal region DUF1985 PF09331.6 CCM05491.1 - 0.15 11.8 2.6 0.55 10.0 1.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) LEP503 PF15221.1 CCM05492.1 - 0.0046 16.6 0.5 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 Lens epithelial cell protein LEP503 SAP PF02037.22 CCM05493.1 - 3e-05 23.4 1.3 5.7e-05 22.5 0.9 1.5 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.8 CCM05493.1 - 0.00055 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 LETM1-like protein F-box PF00646.28 CCM05496.1 - 0.0048 16.5 0.0 0.0048 16.5 0.0 2.5 3 0 0 3 3 3 1 F-box domain Peptidase_U35 PF04586.12 CCM05496.1 - 0.035 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Caudovirus prohead protease F-box-like PF12937.2 CCM05497.1 - 0.0019 17.8 0.0 0.0055 16.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Pro-kuma_activ PF09286.6 CCM05500.1 - 1.1e-35 122.7 0.0 4.1e-35 120.9 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM05500.1 - 8e-10 38.3 3.0 1.6e-09 37.3 2.1 1.4 1 0 0 1 1 1 1 Subtilase family F-box-like PF12937.2 CCM05503.1 - 0.0018 17.9 0.4 0.0061 16.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM05503.1 - 0.014 15.0 0.1 0.058 13.0 0.1 2.2 1 0 0 1 1 1 0 F-box domain DUF2005 PF09407.5 CCM05503.1 - 0.043 12.5 0.1 0.065 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2005) DivIC PF04977.10 CCM05504.1 - 0.00023 20.5 0.2 0.00054 19.3 0.1 1.7 1 1 0 1 1 1 1 Septum formation initiator WEMBL PF05701.6 CCM05504.1 - 0.0062 15.0 0.1 0.0083 14.6 0.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 CCM05504.1 - 0.0076 16.1 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.8 CCM05504.1 - 0.0077 16.0 2.6 0.023 14.4 1.9 1.7 1 1 0 1 1 1 1 Lipoprotein leucine-zipper Paramyx_P_V_C PF03210.8 CCM05504.1 - 0.016 15.1 0.3 0.043 13.6 0.1 1.8 1 1 1 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal FlaC_arch PF05377.6 CCM05504.1 - 0.021 14.6 0.1 2.4 8.1 0.0 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 CCM05504.1 - 0.029 14.0 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4201 PF13870.1 CCM05504.1 - 0.03 13.7 0.1 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Atg14 PF10186.4 CCM05504.1 - 0.039 12.8 0.1 0.057 12.3 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 CCM05504.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 CCM05504.1 - 0.073 11.7 0.1 0.094 11.3 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 CCM05504.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF812 PF05667.6 CCM05504.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CCDC144C PF14915.1 CCM05504.1 - 0.13 11.1 0.5 0.3 9.9 0.4 1.6 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF1664 PF07889.7 CCM05504.1 - 0.14 11.9 0.3 0.37 10.5 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 CCM05504.1 - 0.15 11.9 0.2 0.21 11.4 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4618 PF15397.1 CCM05504.1 - 0.15 11.3 0.0 0.45 9.8 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DSPc PF00782.15 CCM05505.1 - 2.4e-33 114.5 0.0 2.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 CCM05505.1 - 0.0017 17.3 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 CCM05505.1 - 0.0048 16.9 0.0 0.008 16.2 0.0 1.4 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CCM05505.1 - 0.0061 15.9 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MMR_HSR1 PF01926.18 CCM05506.1 - 0.00022 21.1 0.8 0.00045 20.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CCM05506.1 - 0.0045 16.4 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 CCM05506.1 - 0.0091 16.3 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CCM05506.1 - 0.011 16.1 0.3 0.027 14.9 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein AAA_5 PF07728.9 CCM05506.1 - 0.013 15.2 0.0 0.05 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 CCM05506.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 CCM05506.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Septin MobB PF03205.9 CCM05506.1 - 0.025 14.3 0.1 0.055 13.1 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 CCM05506.1 - 0.028 13.5 0.5 0.077 12.0 0.0 1.9 2 1 0 2 2 2 0 AIG1 family T2SE PF00437.15 CCM05506.1 - 0.04 12.8 0.1 0.093 11.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 CCM05506.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 CCM05506.1 - 0.067 13.3 0.1 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCM05506.1 - 0.085 12.8 1.6 0.34 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 CCM05506.1 - 0.18 10.7 0.0 0.3 10.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain SMP PF04927.7 CCM05507.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Seed maturation protein Sugar_tr PF00083.19 CCM05508.1 - 9.7e-41 139.7 14.9 2.9e-40 138.2 10.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM05508.1 - 3.3e-19 68.8 28.1 9.1e-12 44.3 3.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PrgI PF12666.2 CCM05508.1 - 0.55 10.4 5.0 9.2 6.4 0.0 3.5 3 0 0 3 3 3 0 PrgI family protein FMO-like PF00743.14 CCM05509.1 - 3.9e-31 107.8 0.0 2.8e-21 75.3 0.0 2.7 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCM05509.1 - 1.5e-13 51.3 0.0 3.3e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCM05509.1 - 2.7e-06 27.4 0.0 6.5e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM05509.1 - 3.7e-06 26.0 0.0 0.00041 19.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCM05509.1 - 0.00067 19.6 2.3 0.00076 19.4 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCM05509.1 - 0.0017 18.1 0.0 0.0017 18.1 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 CCM05509.1 - 0.0035 16.4 0.1 0.7 8.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Ras PF00071.17 CCM05510.1 - 1.1e-50 171.1 0.0 1.4e-49 167.5 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CCM05510.1 - 2.2e-13 50.7 0.0 4.9e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein O-FucT PF10250.4 CCM05510.1 - 5.5e-12 45.4 0.6 2.7e-05 23.4 0.1 3.3 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase Arf PF00025.16 CCM05510.1 - 0.00013 21.2 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCM05510.1 - 0.053 12.7 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AKAP7_NLS PF10469.4 CCM05511.1 - 4.2e-21 75.6 0.0 1.1e-19 71.0 0.0 2.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Dyp_perox PF04261.7 CCM05512.1 - 2.3e-05 23.3 0.0 0.013 14.2 0.0 3.0 3 0 0 3 3 3 2 Dyp-type peroxidase family 4HBT PF03061.17 CCM05515.1 - 2.3e-08 34.0 0.3 4.5e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Thioesterase superfamily EutB PF06751.6 CCM05515.1 - 0.087 11.1 0.1 1.3 7.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine ammonia lyase large subunit (EutB) ubiquitin PF00240.18 CCM05516.1 - 1.4e-23 82.0 0.0 1.6e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCM05516.1 - 1.5e-14 53.4 0.2 1.6e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCM05516.1 - 0.0004 20.5 0.0 0.00076 19.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain SAP18 PF06487.7 CCM05517.1 - 6.5e-23 80.8 0.0 8.4e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF1777 PF08648.7 CCM05517.1 - 0.052 13.2 24.4 0.078 12.7 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Atrophin-1 PF03154.10 CCM05517.1 - 0.11 10.6 3.6 0.14 10.2 2.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family TAF4 PF05236.9 CCM05518.1 - 1.3e-26 93.4 0.7 1.3e-26 93.4 0.5 2.7 3 0 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family TSA PF03249.8 CCM05518.1 - 6.2 5.2 14.9 13 4.2 10.3 1.4 1 0 0 1 1 1 0 Type specific antigen Nucleoporin_FG PF13634.1 CCM05519.1 - 0.0094 16.1 192.0 0.48 10.6 29.4 6.3 1 1 3 4 4 4 2 Nucleoporin FG repeat region Nucleoplasmin PF03066.10 CCM05526.1 - 5.6 6.4 7.1 8.3 5.9 4.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin Pkinase PF00069.20 CCM05529.1 - 6e-55 186.1 0.0 7.9e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05529.1 - 5.3e-29 101.0 0.0 6.7e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM05529.1 - 5.6e-06 26.2 0.0 0.00073 19.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CCM05529.1 - 0.00061 18.8 0.0 0.0017 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCM05529.1 - 0.0091 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CCM05529.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase 4HBT PF03061.17 CCM05530.1 - 0.00049 20.1 1.3 0.001 19.1 0.9 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Ham1p_like PF01725.11 CCM05531.1 - 2.5e-54 183.5 0.0 3e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family SMC_N PF02463.14 CCM05532.1 - 9.3e-20 70.8 0.2 1.5e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCM05532.1 - 2.5e-18 67.1 0.1 2.5e-18 67.1 0.0 5.3 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 CCM05532.1 - 0.00012 22.1 4.1 0.0006 19.8 1.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_13 PF13166.1 CCM05532.1 - 0.0029 16.1 61.7 0.0029 16.1 0.0 4.7 3 2 1 4 4 4 3 AAA domain HTH_16 PF12645.2 CCM05532.1 - 0.0031 17.3 0.0 0.024 14.5 0.0 2.6 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_29 PF13555.1 CCM05532.1 - 0.0056 16.1 0.0 0.029 13.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CCM05532.1 - 0.021 14.2 0.2 0.17 11.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCM05532.1 - 0.16 12.7 0.0 0.16 12.7 0.0 4.3 4 2 0 4 4 4 0 AAA domain ABC_tran PF00005.22 CCM05532.1 - 0.2 11.9 0.0 0.2 11.9 0.0 4.7 3 2 0 3 3 3 0 ABC transporter RNase_PH PF01138.16 CCM05533.1 - 2.3e-27 95.8 0.0 4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCM05533.1 - 0.00022 21.0 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Semialdhyde_dhC PF02774.13 CCM05534.1 - 4.1e-38 131.0 0.0 5.9e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CCM05534.1 - 1.1e-22 80.5 0.0 2.4e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CCM05534.1 - 0.042 13.7 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 CCM05534.1 - 0.072 13.6 0.0 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Rab5ip PF07019.7 CCM05535.1 - 3.1e-16 59.2 1.1 4.2e-16 58.8 0.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_11 PF13414.1 CCM05537.1 - 2e-14 52.9 0.1 4.8e-07 29.3 0.0 5.5 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.1 CCM05537.1 - 1.3e-08 34.5 1.2 0.0013 18.5 0.0 5.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCM05537.1 - 2e-08 33.4 3.9 0.081 12.8 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCM05537.1 - 7.5e-08 31.9 0.0 0.028 14.6 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCM05537.1 - 1.8e-07 30.4 0.1 2.2 8.0 0.0 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCM05537.1 - 2.9e-06 27.8 3.5 0.007 17.0 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCM05537.1 - 4.3e-05 22.9 2.6 4.2 7.3 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCM05537.1 - 0.0012 19.2 13.4 2.9 8.7 0.0 7.3 6 2 2 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCM05537.1 - 0.0026 17.5 10.9 0.0032 17.2 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCM05537.1 - 0.018 14.9 2.5 12 5.9 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCM05537.1 - 0.021 14.6 0.0 9.7 6.2 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PH PF00169.24 CCM05538.1 - 1.6e-13 50.7 0.0 4.1e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 CCM05538.1 - 6.5e-13 48.3 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 CCM05538.1 - 8.9e-13 47.6 0.3 2.4e-12 46.2 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 CCM05538.1 - 1.5e-11 44.2 0.1 3.6e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 CCM05538.1 - 1.9e-09 36.7 0.5 4.8e-09 35.4 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CCM05538.1 - 2.7e-09 36.3 0.5 6.7e-09 35.1 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain PH_11 PF15413.1 CCM05538.1 - 0.0079 16.4 0.2 0.018 15.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 CCM05538.1 - 0.011 15.7 0.2 0.034 14.1 0.1 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.11 CCM05538.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain BRO1 PF03097.13 CCM05539.1 - 0.0062 15.3 0.6 0.011 14.5 0.4 1.3 1 0 0 1 1 1 1 BRO1-like domain UAF_Rrn10 PF05234.6 CCM05539.1 - 0.0085 16.1 0.0 0.071 13.1 0.0 2.1 2 0 0 2 2 2 1 UAF complex subunit Rrn10 Vfa1 PF08432.5 CCM05539.1 - 0.042 13.8 2.8 0.1 12.6 2.0 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_L13 PF00572.13 CCM05540.1 - 4e-46 156.2 0.1 4.7e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 X PF00739.14 CCM05540.1 - 0.07 13.0 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Trans-activation protein X Peptidase_M24 PF00557.19 CCM05542.1 - 4.2e-40 137.5 0.0 5.2e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 2OG-FeII_Oxy_2 PF13532.1 CCM05543.1 - 8.8e-15 55.0 0.0 1.5e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CCM05543.1 - 5.8e-05 23.3 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 CCM05546.1 - 5.7e-13 49.2 2.7 7.7e-13 48.8 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM05546.1 - 0.053 13.2 0.1 0.32 10.7 0.1 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Asp PF00026.18 CCM05547.1 - 3e-65 220.5 0.4 3.6e-65 220.2 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCM05547.1 - 2.2e-07 31.2 0.0 0.012 16.1 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 CCM05547.1 - 4.1e-06 26.8 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Syja_N PF02383.13 CCM05549.1 - 1.4e-74 250.7 0.0 1.8e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CCM05549.1 - 1.5e-18 67.6 0.0 2.6e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3449 PF11931.3 CCM05550.1 - 7.2e-71 237.7 0.2 7.2e-71 237.7 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-met PF12874.2 CCM05550.1 - 1.8e-06 27.9 5.8 4e-06 26.8 0.7 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.3 CCM05550.1 - 1.6e-05 24.3 1.1 3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 CCM05550.1 - 1.9e-05 24.6 0.5 1.9e-05 24.6 0.4 2.9 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCM05550.1 - 0.00059 19.9 1.4 0.044 13.8 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 CCM05550.1 - 0.1 12.2 4.3 0.67 9.6 0.1 2.7 2 0 0 2 2 2 0 DBF zinc finger DUF951 PF06107.6 CCM05550.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DEAD PF00270.24 CCM05551.1 - 6.9e-42 142.7 0.1 1.4e-41 141.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM05551.1 - 8.2e-28 96.0 0.2 1.7e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CCM05551.1 - 0.011 15.4 0.1 0.031 14.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 CCM05551.1 - 0.017 14.9 0.0 0.056 13.2 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCM05551.1 - 0.026 14.6 0.2 0.11 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 CCM05551.1 - 0.041 12.9 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) RRM_1 PF00076.17 CCM05553.1 - 4e-19 68.0 1.2 4.4e-19 67.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM05553.1 - 1.4e-15 57.0 0.0 2.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM05553.1 - 3.5e-10 39.5 0.0 3.5e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCM05553.1 - 0.098 12.5 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 RNA binding motif Usp PF00582.21 CCM05553.1 - 0.13 12.4 0.2 0.17 12.0 0.1 1.1 1 0 0 1 1 1 0 Universal stress protein family RNA_pol_Rpb1_5 PF04998.12 CCM05554.1 - 9.7e-86 287.4 0.0 6.4e-85 284.7 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCM05554.1 - 8.6e-60 201.4 0.0 1.8e-59 200.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCM05554.1 - 6.1e-37 126.7 0.0 1.2e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 CCM05554.1 - 1.1e-24 87.3 2.5 2.9e-17 62.9 0.0 3.3 1 1 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 CCM05554.1 - 5e-21 74.4 0.0 1.4e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TPR_14 PF13428.1 CCM05556.1 - 0.0064 17.0 0.5 1.2 9.9 0.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat RIX1 PF08167.7 CCM05557.1 - 6.7e-24 84.4 1.0 6.7e-24 84.4 0.7 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Sec10 PF07393.6 CCM05558.1 - 1e-106 357.8 0.2 1.4e-106 357.3 0.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 Filament PF00038.16 CCM05558.1 - 0.016 14.7 2.6 0.031 13.7 1.8 1.6 1 0 0 1 1 1 0 Intermediate filament protein Exo70 PF03081.10 CCM05558.1 - 0.017 13.9 1.4 0.95 8.1 0.1 2.6 2 1 0 2 2 2 0 Exo70 exocyst complex subunit CTD_bind PF04818.8 CCM05558.1 - 0.02 15.1 0.5 0.5 10.6 0.0 3.0 2 1 0 2 2 2 0 RNA polymerase II-binding domain. Laminin_II PF06009.7 CCM05558.1 - 0.057 13.1 0.5 0.16 11.7 0.3 1.7 1 0 0 1 1 1 0 Laminin Domain II DUF1664 PF07889.7 CCM05558.1 - 0.093 12.5 1.0 0.28 11.0 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.15 CCM05558.1 - 0.1 11.6 5.4 0.21 10.6 3.7 1.5 1 1 0 1 1 1 0 Tropomyosin IFT20 PF14931.1 CCM05558.1 - 0.11 12.4 5.1 0.061 13.2 1.6 2.0 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Occludin_ELL PF07303.8 CCM05558.1 - 0.12 13.0 2.6 0.26 12.0 0.3 2.5 1 1 1 2 2 2 0 Occludin homology domain Sec10 PF07393.6 CCM05559.1 - 6.4e-110 368.4 0.0 8.5e-110 368.0 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 OppC_N PF12911.2 CCM05560.1 - 0.0044 16.3 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C Amidohydro_2 PF04909.9 CCM05562.1 - 1.6e-25 90.2 0.2 5.6e-25 88.4 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 CCM05562.1 - 0.085 12.0 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 TatD related DNase CP12 PF02672.10 CCM05562.1 - 0.16 12.4 0.4 0.72 10.3 0.1 2.1 1 1 1 2 2 2 0 CP12 domain Asparaginase PF00710.15 CCM05562.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Asparaginase QRPTase_C PF01729.14 CCM05563.1 - 2.6e-50 170.2 0.1 3.2e-50 169.9 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 CCM05563.1 - 1.2e-21 76.3 0.0 3.3e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain GPI-anchored PF10342.4 CCM05564.1 - 3.3e-17 62.7 7.3 3.3e-17 62.7 5.1 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SIP1 PF04938.7 CCM05565.1 - 1e-17 64.2 0.1 1.4e-16 60.5 0.1 2.0 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3245 PF11595.3 CCM05566.1 - 2.1e-06 28.0 0.2 2.1e-06 28.0 0.1 3.1 3 1 1 4 4 4 2 Protein of unknown function (DUF3245) Protoglobin PF11563.3 CCM05568.1 - 2e-35 121.7 0.0 2.6e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protoglobin DSPc PF00782.15 CCM05569.1 - 3.3e-30 104.3 0.0 3.9e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCM05569.1 - 0.00033 20.0 0.0 0.00041 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Tubulin PF00091.20 CCM05570.1 - 4.7e-67 225.9 0.0 8e-67 225.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCM05570.1 - 3.9e-46 156.1 0.0 7.4e-46 155.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Abhydrolase_3 PF07859.8 CCM05570.1 - 9.6e-33 113.5 0.1 3.9e-26 91.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CCM05570.1 - 9.4e-06 24.4 0.0 4.1e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Tubulin_3 PF14881.1 CCM05570.1 - 0.0023 17.4 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 CCM05570.1 - 0.045 13.3 0.2 6.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Lipase (class 3) Tubulin PF00091.20 CCM05571.1 - 1e-56 192.1 0.0 1.6e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCM05571.1 - 3.2e-45 153.2 0.0 4.6e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.20 CCM05571.1 - 0.013 15.1 0.1 4 7.0 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) Tubulin_3 PF14881.1 CCM05571.1 - 0.16 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Bin3 PF06859.7 CCM05572.1 - 3.1e-36 123.6 0.0 3.8e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 CCM05572.1 - 1.3e-05 25.7 0.0 2.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM05572.1 - 6.5e-05 23.3 0.0 0.00016 22.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM05572.1 - 0.00012 21.8 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM05572.1 - 0.00062 20.1 0.0 0.0012 19.2 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM05572.1 - 0.0036 16.9 0.0 0.0042 16.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 CCM05572.1 - 0.03 13.6 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 CCM05572.1 - 0.031 13.4 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_25 PF13649.1 CCM05572.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CCM05572.1 - 0.16 11.0 0.0 0.46 9.5 0.0 1.7 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family HAD_2 PF13419.1 CCM05573.1 - 4.8e-18 65.9 0.0 9.8e-18 64.9 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCM05573.1 - 3.8e-13 50.3 0.1 6.3e-12 46.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCM05573.1 - 8.6e-12 44.6 0.0 1.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCM05573.1 - 0.0024 18.0 0.0 0.0045 17.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CPSF100_C PF13299.1 CCM05574.1 - 3.7e-26 92.2 0.0 3.7e-26 92.2 0.0 2.9 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CCM05574.1 - 2.8e-22 78.9 0.0 8.3e-22 77.4 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain CDC45 PF02724.9 CCM05574.1 - 1.4 6.8 7.7 2.1 6.2 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 CCM05574.1 - 5.1 4.7 9.2 8 4.1 6.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Arf PF00025.16 CCM05575.1 - 8.7e-79 262.7 0.1 1e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCM05575.1 - 1.4e-14 53.7 0.0 1.7e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CCM05575.1 - 9.5e-13 47.8 0.0 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CCM05575.1 - 3e-12 45.9 1.3 3.7e-09 35.7 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCM05575.1 - 4.5e-11 42.3 0.0 5.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCM05575.1 - 2.2e-09 37.8 0.0 3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCM05575.1 - 5.3e-06 26.3 0.0 6.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CCM05575.1 - 0.007 15.4 0.3 0.013 14.5 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CCM05575.1 - 0.0097 15.3 0.1 0.084 12.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CCM05575.1 - 0.087 12.6 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CCM05575.1 - 0.13 11.7 0.3 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sec15 PF04091.7 CCM05576.1 - 6e-69 232.7 1.0 1.3e-68 231.5 0.7 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 CCM05576.1 - 2.3e-07 30.8 0.6 2.3e-07 30.8 0.4 3.5 3 1 1 4 4 4 1 Golgi transport complex subunit 5 Vps51 PF08700.6 CCM05576.1 - 3.7e-05 23.4 2.3 8.9e-05 22.2 0.3 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.9 CCM05576.1 - 0.0012 18.5 2.3 0.0012 18.5 1.6 2.1 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 CCM05576.1 - 0.0027 17.4 1.6 0.018 14.7 0.0 2.8 3 0 0 3 3 3 1 Exocyst complex component Sec5 COG2 PF06148.6 CCM05576.1 - 0.013 15.3 0.9 0.013 15.3 0.6 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DDE_Tnp_ISL3 PF01610.12 CCM05576.1 - 0.035 13.6 0.1 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Transposase AAA_14 PF13173.1 CCM05576.1 - 0.097 12.5 0.9 0.39 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain Cortex-I_coil PF09304.5 CCM05576.1 - 0.18 11.8 3.7 1.9 8.5 0.3 3.3 2 1 1 3 3 3 0 Cortexillin I, coiled coil DUF2450 PF10475.4 CCM05576.1 - 0.77 8.5 9.5 0.7 8.7 0.6 3.3 3 1 1 4 4 4 0 Protein of unknown function N-terminal domain (DUF2450) tRNA-synt_1c PF00749.16 CCM05577.1 - 1.4e-103 345.8 0.0 1.8e-103 345.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CCM05577.1 - 1.8e-32 112.4 0.0 3.6e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 CCM05577.1 - 5.5e-28 97.5 0.1 8.9e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 CCM05577.1 - 4.5e-08 33.6 0.8 4.5e-08 33.6 0.6 2.3 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 AAA PF00004.24 CCM05578.1 - 9.1e-22 77.6 0.0 1.6e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCM05578.1 - 0.00016 21.7 0.2 0.091 12.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 CCM05578.1 - 0.042 13.8 0.0 1.1 9.2 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain DAP3 PF10236.4 CCM05578.1 - 0.042 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_33 PF13671.1 CCM05578.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCM05578.1 - 0.15 11.8 0.0 1 9.1 0.0 2.3 3 0 0 3 3 3 0 Part of AAA domain T2SE PF00437.15 CCM05578.1 - 0.18 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MAS20 PF02064.10 CCM05579.1 - 9e-19 67.5 0.3 2.8e-18 65.9 0.2 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor SET PF00856.23 CCM05579.1 - 2.2e-07 31.3 0.0 2.6e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 SET domain Ecl1 PF12855.2 CCM05579.1 - 0.00058 19.0 0.8 0.0012 18.1 0.6 1.5 1 0 0 1 1 1 1 Life-span regulatory factor PGC7_Stella PF15549.1 CCM05579.1 - 0.41 10.6 5.1 0.4 10.6 0.2 2.4 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Metallothio_Pro PF02069.11 CCM05579.1 - 0.68 9.7 5.1 1.3 8.9 0.7 2.5 2 0 0 2 2 2 0 Prokaryotic metallothionein WD40 PF00400.27 CCM05582.1 - 3.9e-59 194.5 17.7 6.9e-15 54.2 0.0 6.1 6 0 0 6 6 5 4 WD domain, G-beta repeat eIF2A PF08662.6 CCM05582.1 - 9.2e-08 32.0 0.0 0.0048 16.6 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 CCM05582.1 - 8.7e-07 28.7 0.0 2.8e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain PD40 PF07676.7 CCM05582.1 - 8.6e-06 25.3 0.7 4.7 6.9 0.0 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 CCM05582.1 - 0.0003 19.1 0.1 0.048 11.9 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 CCM05582.1 - 0.00044 18.5 0.2 0.81 7.7 0.0 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCM05582.1 - 0.0031 16.3 0.1 5 5.7 0.0 3.7 1 1 2 4 4 4 1 Nup133 N terminal like AAA_16 PF13191.1 CCM05582.1 - 0.0083 16.1 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Proteasome_A_N PF10584.4 CCM05582.1 - 0.011 15.0 1.4 59 3.1 0.0 4.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature RicinB_lectin_2 PF14200.1 CCM05582.1 - 0.026 14.8 0.2 0.2 12.0 0.2 2.4 2 1 1 3 3 2 0 Ricin-type beta-trefoil lectin domain-like PQQ_3 PF13570.1 CCM05582.1 - 0.036 14.3 5.3 40 4.6 0.1 4.3 4 0 0 4 4 4 0 PQQ-like domain NB-ARC PF00931.17 CCM05582.1 - 0.037 12.8 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_2 PF07724.9 CCM05583.1 - 2.4e-33 115.4 0.0 1e-31 110.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CCM05583.1 - 1.8e-19 69.3 1.9 7.7e-19 67.3 0.1 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CCM05583.1 - 1.4e-18 67.3 0.1 1.4e-09 38.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCM05583.1 - 2.2e-10 40.3 0.0 6e-06 26.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCM05583.1 - 1.1e-08 35.2 4.2 0.00061 19.8 0.0 4.2 3 2 2 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 CCM05583.1 - 7e-08 32.6 0.3 0.014 15.5 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 CCM05583.1 - 1.3e-07 32.4 2.2 0.005 17.6 0.0 4.1 5 0 0 5 5 4 2 AAA domain AAA_23 PF13476.1 CCM05583.1 - 1.4e-06 28.7 2.8 0.1 12.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CCM05583.1 - 1.5e-06 28.5 0.1 0.077 13.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 CCM05583.1 - 1.2e-05 25.2 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CCM05583.1 - 0.00016 21.1 0.5 0.17 11.3 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein ABC_tran PF00005.22 CCM05583.1 - 0.00035 20.8 0.7 0.055 13.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 CCM05583.1 - 0.00072 19.2 0.0 1.2 8.9 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 CCM05583.1 - 0.0008 18.8 0.0 2.5 7.4 0.0 3.2 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 CCM05583.1 - 0.00086 18.5 0.1 0.4 9.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCM05583.1 - 0.0011 19.1 0.0 0.86 9.8 0.0 2.9 3 0 0 3 3 2 1 RNA helicase RuvB_N PF05496.7 CCM05583.1 - 0.0011 18.0 0.4 0.54 9.2 0.0 2.9 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 CCM05583.1 - 0.0012 18.2 0.1 0.0035 16.8 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 CCM05583.1 - 0.0016 18.4 0.5 1.9 8.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 CCM05583.1 - 0.0019 17.9 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 CCM05583.1 - 0.0042 16.6 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCM05583.1 - 0.0069 15.5 2.6 0.1 11.6 0.0 2.8 3 1 0 3 3 3 1 Zeta toxin NTPase_1 PF03266.10 CCM05583.1 - 0.01 15.5 0.3 6.7 6.3 0.0 3.6 4 0 0 4 4 4 0 NTPase NACHT PF05729.7 CCM05583.1 - 0.015 14.9 0.0 2.9 7.5 0.0 2.8 2 1 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 CCM05583.1 - 0.033 13.8 5.7 10 5.7 0.0 4.5 3 2 2 5 5 5 0 Archaeal ATPase AAA_29 PF13555.1 CCM05583.1 - 0.048 13.2 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 CCM05583.1 - 0.061 12.5 0.1 2.6 7.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF258 SRP54 PF00448.17 CCM05583.1 - 0.065 12.6 0.0 0.67 9.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 CCM05583.1 - 0.1 12.1 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein LCD1 PF09798.4 CCM05583.1 - 2.5 5.9 5.3 4.3 5.2 3.7 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein APG6 PF04111.7 CCM05583.1 - 6.7 5.6 9.1 11 4.9 6.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 SHS2_Rpb7-N PF03876.12 CCM05584.1 - 8.8e-15 54.5 0.0 1.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CCM05584.1 - 1.5e-11 44.1 0.6 3.5e-11 43.0 0.4 1.6 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 CCM05584.1 - 0.0021 18.2 0.1 0.0037 17.4 0.1 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 BNR PF02012.15 CCM05585.1 - 0.0066 16.1 0.4 2 8.5 0.0 3.1 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR PF02012.15 CCM05586.1 - 2.4e-10 38.6 45.4 0.22 11.4 0.0 10.1 9 0 0 9 9 9 8 BNR/Asp-box repeat Mo-co_dimer PF03404.11 CCM05586.1 - 0.084 12.5 0.9 9.4 5.8 0.1 4.3 5 1 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain UCR_UQCRX_QCR9 PF05365.7 CCM05586.1 - 0.42 10.2 3.3 8.4 6.1 0.0 3.3 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-C2H2_4 PF13894.1 CCM05587.1 - 2 8.9 17.2 7.7 7.1 1.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM05587.1 - 3.7 8.0 12.8 7.9 7.0 1.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type ADH_zinc_N PF00107.21 CCM05588.1 - 2.6e-15 56.1 0.0 4.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM05588.1 - 7.2e-05 22.5 0.1 0.00021 20.9 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Plant_vir_prot PF01307.12 CCM05588.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Plant viral movement protein ADH_zinc_N_2 PF13602.1 CCM05588.1 - 0.026 15.4 0.0 0.053 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F-box-like PF12937.2 CCM05589.1 - 0.023 14.4 0.7 0.053 13.2 0.5 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 CCM05589.1 - 0.12 12.0 1.5 0.33 10.6 0.1 2.3 2 0 0 2 2 2 0 F-box domain GMC_oxred_N PF00732.14 CCM05590.1 - 5.3e-59 199.7 0.0 8.4e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM05590.1 - 1.5e-33 116.1 0.0 3.1e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM05590.1 - 9.1e-06 24.8 0.8 0.0003 19.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCM05590.1 - 4.6e-05 23.3 0.5 0.0001 22.2 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCM05590.1 - 0.00034 19.5 3.0 0.0085 14.9 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CCM05590.1 - 0.0022 18.0 0.0 0.41 10.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCM05590.1 - 0.0036 17.2 0.3 0.053 13.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM05590.1 - 0.0038 16.1 0.4 0.0059 15.5 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 CCM05590.1 - 0.0086 14.5 1.6 0.017 13.5 0.1 2.1 2 1 1 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.9 CCM05590.1 - 0.08 11.5 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 CCM05590.1 - 0.095 12.4 0.2 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 CCM05590.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family dCMP_cyt_deam_1 PF00383.17 CCM05591.1 - 2.6e-17 62.3 0.2 4.2e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CCM05591.1 - 2.5e-08 33.9 0.5 1.1e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CCM05591.1 - 0.00035 20.0 2.0 0.13 11.6 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases ADH_N PF08240.7 CCM05591.1 - 0.018 14.7 0.2 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Phos_pyr_kin PF08543.7 CCM05591.1 - 0.12 11.5 0.2 0.19 10.8 0.1 1.4 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase FAD_binding_4 PF01565.18 CCM05592.1 - 2.4e-18 65.9 2.2 7e-18 64.4 1.6 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CCM05592.1 - 2.8e-07 30.3 0.4 5.9e-07 29.3 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like DnaJ PF00226.26 CCM05592.1 - 0.011 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain Cytokin-bind PF09265.5 CCM05592.1 - 0.045 12.9 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding GCV_T PF01571.16 CCM05594.1 - 3.3e-65 219.3 0.0 4.2e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCM05594.1 - 2.3e-24 85.2 0.1 4.9e-24 84.1 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF1900 PF08954.6 CCM05595.1 - 1.9e-48 163.4 0.0 1.7e-47 160.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CCM05595.1 - 1e-25 89.1 0.1 1.8e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CCM05595.1 - 6.2e-22 76.6 1.3 1.6e-08 34.0 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat CCDC144C PF14915.1 CCM05595.1 - 0.005 15.8 1.4 0.0064 15.4 1.0 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF3053 PF11254.3 CCM05595.1 - 0.22 10.7 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) RCC1 PF00415.13 CCM05596.1 - 7.9e-22 77.2 3.3 0.00011 22.3 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CCM05596.1 - 1e-13 51.2 0.0 1e-06 28.6 0.0 3.4 2 1 1 3 3 3 2 BTB/POZ domain Ank_4 PF13637.1 CCM05596.1 - 6.3e-13 48.8 2.1 2.1e-09 37.6 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCM05596.1 - 2e-09 37.3 3.0 2.5e-06 27.5 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 CCM05596.1 - 9.9e-08 31.4 5.3 1.4e-06 27.7 0.0 4.7 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 CCM05596.1 - 3.4e-07 30.5 0.0 1.1e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCM05596.1 - 6.8e-07 28.9 0.3 0.062 13.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 CCM05596.1 - 1.9e-05 24.2 0.3 0.028 14.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Nuc_deoxyrib_tr PF05014.10 CCM05596.1 - 0.18 11.6 0.0 0.5 10.2 0.0 1.7 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Epimerase PF01370.16 CCM05598.1 - 1.3e-17 64.0 0.0 1.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM05598.1 - 1.3e-10 41.5 3.3 3.7e-10 40.0 2.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCM05598.1 - 1.1e-08 34.1 0.1 2e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CCM05598.1 - 1.1e-06 28.0 2.3 2e-06 27.2 1.6 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CCM05598.1 - 0.0018 18.1 3.1 0.0036 17.2 2.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CCM05598.1 - 0.0076 15.2 0.3 0.16 10.8 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CCM05598.1 - 0.0096 14.8 0.2 0.015 14.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 CCM05599.1 - 6.9e-12 45.2 0.1 1.5e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM05599.1 - 1.2e-09 38.4 3.0 2.4e-09 37.4 2.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCM05599.1 - 6.2e-08 32.1 0.4 6e-07 28.9 0.8 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 CCM05599.1 - 0.089 11.6 0.0 10 4.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein adh_short PF00106.20 CCM05599.1 - 1.1 9.2 4.1 2.9 7.7 2.8 1.8 1 1 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.20 CCM05600.1 - 7.7e-19 68.2 0.4 1.9e-18 66.9 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM05600.1 - 1e-07 31.7 0.1 2.1e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM05600.1 - 2.7e-05 24.0 0.1 5.2e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM05600.1 - 0.0015 18.5 0.1 0.0036 17.3 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCM05600.1 - 0.039 13.3 0.1 0.056 12.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_33 PF10017.4 CCM05601.1 - 1.6e-33 115.2 0.0 2.6e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 CCM05601.1 - 2e-21 76.5 2.0 2.5e-11 43.4 0.0 2.5 3 0 0 3 3 3 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 CCM05601.1 - 0.00056 20.2 0.2 0.0012 19.1 0.2 1.5 1 0 0 1 1 1 1 DinB superfamily zf-DHHC PF01529.15 CCM05602.1 - 0.0005 19.5 5.3 0.0005 19.5 3.7 2.0 2 1 1 3 3 3 1 DHHC palmitoyltransferase DNA_pol_A_exo1 PF01612.15 CCM05603.1 - 2.3e-48 163.9 0.7 3.3e-48 163.4 0.5 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 CCM05603.1 - 4.7e-13 48.6 0.1 1.5e-12 47.0 0.0 2.0 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.7 CCM05603.1 - 0.11 12.7 0.2 0.69 10.2 0.1 2.4 3 0 0 3 3 3 0 PMC2NT (NUC016) domain DUF3184 PF11380.3 CCM05604.1 - 0.0013 16.8 0.2 0.005 14.8 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3184) Tubulin PF00091.20 CCM05604.1 - 0.3 10.8 0.0 0.55 10.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain SNF5 PF04855.7 CCM05607.1 - 1.8e-70 237.1 0.5 3.1e-70 236.4 0.3 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Elf1 PF05129.8 CCM05607.1 - 0.035 13.7 0.3 0.12 12.0 0.2 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF563 PF04577.9 CCM05607.1 - 0.08 12.8 0.0 0.73 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF563) GATA PF00320.22 CCM05607.1 - 0.5 9.7 5.6 1.1 8.7 3.9 1.6 1 0 0 1 1 1 0 GATA zinc finger TPT PF03151.11 CCM05608.1 - 4.3e-26 91.4 15.9 5.5e-23 81.2 2.8 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 CCM05608.1 - 7.1e-10 38.2 14.4 2.9e-06 26.4 3.2 2.5 2 1 1 3 3 3 2 UAA transporter family EamA PF00892.15 CCM05608.1 - 4.3e-06 26.7 29.2 0.0021 18.0 8.8 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CCM05608.1 - 0.0074 16.4 5.4 0.0074 16.4 3.7 3.0 2 1 1 3 3 3 2 Multidrug resistance efflux transporter zf-C3HC4_3 PF13920.1 CCM05609.1 - 3.1e-07 29.9 4.6 3.1e-07 29.9 3.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCM05609.1 - 2.7e-06 27.3 7.5 2.7e-06 27.3 5.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCM05609.1 - 4.2e-06 26.4 8.0 4.2e-06 26.4 5.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCM05609.1 - 5.4e-06 25.9 6.4 5.4e-06 25.9 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM05609.1 - 6.6e-05 22.7 4.0 6.6e-05 22.7 2.8 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCM05609.1 - 6.7e-05 22.5 4.7 6.7e-05 22.5 3.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCM05609.1 - 0.0058 16.3 3.5 0.012 15.3 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CCM05609.1 - 0.018 14.8 0.1 0.018 14.8 0.1 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein WH1 PF00568.18 CCM05610.1 - 1.7e-12 47.0 0.0 3.2e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 WH1 domain PBD PF00786.23 CCM05610.1 - 0.025 14.9 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain Pyr_redox_2 PF07992.9 CCM05611.1 - 1.1e-25 90.7 0.0 3.4e-25 89.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM05611.1 - 5.2e-13 49.2 0.0 4e-10 39.9 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM05611.1 - 0.0019 18.3 0.0 0.011 15.8 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 CCM05612.1 - 3.2e-22 78.7 23.5 4.8e-16 58.4 13.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily AAA_18 PF13238.1 CCM05612.1 - 0.12 12.6 0.1 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain FNIP_M PF14637.1 CCM05612.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Polysacc_deac_1 PF01522.16 CCM05613.1 - 0.054 13.1 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide deacetylase Pyridoxal_deC PF00282.14 CCM05614.1 - 1.5e-112 375.7 0.0 1.8e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Smg4_UPF3 PF03467.10 CCM05615.1 - 4.4e-32 111.4 0.4 4.4e-32 111.4 0.3 1.8 2 0 0 2 2 2 1 Smg-4/UPF3 family Med3 PF11593.3 CCM05615.1 - 0.00099 18.4 26.3 0.043 13.0 2.4 2.4 1 1 1 2 2 2 2 Mediator complex subunit 3 fungal DUF4121 PF13497.1 CCM05615.1 - 0.059 12.3 0.1 0.09 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) SYF2 PF08231.7 CCM05616.1 - 2.2e-49 167.4 10.0 2.2e-49 167.4 6.9 1.9 2 0 0 2 2 2 1 SYF2 splicing factor 5_nucleotid PF05761.9 CCM05616.1 - 2.5 6.5 11.9 11 4.4 8.2 2.1 1 1 0 1 1 1 0 5' nucleotidase family GPI-anchored PF10342.4 CCM05617.1 - 3.1e-08 33.9 2.8 3.1e-08 33.9 1.9 2.1 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NmrA PF05368.8 CCM05618.1 - 4.5e-37 127.5 0.0 1.4e-36 125.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family ORC3_N PF07034.6 CCM05618.1 - 3e-16 59.3 0.5 1.2e-15 57.3 0.4 1.9 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus NAD_binding_10 PF13460.1 CCM05618.1 - 1.1e-12 48.3 0.0 3.5e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCM05618.1 - 0.00015 20.5 0.0 0.00025 19.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCM05618.1 - 0.016 14.6 0.0 0.095 12.1 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 CCM05618.1 - 0.043 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain GST_N_3 PF13417.1 CCM05619.1 - 5.7e-17 61.7 0.0 9.4e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCM05619.1 - 7.6e-17 61.2 0.0 1.3e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCM05619.1 - 1.1e-14 54.1 0.0 1.6e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCM05619.1 - 2.7e-12 46.5 0.0 4.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM05619.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCM05619.1 - 0.00088 19.7 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UcrQ PF02939.11 CCM05620.1 - 9.2e-18 63.8 3.1 1.7e-16 59.7 2.2 2.1 1 1 0 1 1 1 1 UcrQ family AtpR PF12966.2 CCM05620.1 - 0.03 14.4 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 N-ATPase, AtpR subunit DUF2741 PF10890.3 CCM05620.1 - 0.084 13.0 0.3 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2741) Melibiase PF02065.13 CCM05621.1 - 0.00025 19.8 0.1 0.0011 17.7 0.1 1.8 1 1 0 1 1 1 1 Melibiase SAE2 PF08573.5 CCM05622.1 - 1.6e-14 54.3 4.3 1.6e-14 54.3 3.0 3.6 4 1 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus TPR_MLP1_2 PF07926.7 CCM05622.1 - 0.04 13.6 13.0 0.032 13.9 0.8 3.5 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.1 CCM05622.1 - 1.6 8.8 12.6 0.15 12.2 2.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Gpi1 PF05024.10 CCM05623.1 - 3.8e-50 170.1 11.8 3.8e-50 170.1 8.2 1.9 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) F-box-like PF12937.2 CCM05624.1 - 0.049 13.3 1.0 0.11 12.1 0.7 1.7 1 0 0 1 1 1 0 F-box-like GPI-anchored PF10342.4 CCM05625.1 - 4.5e-05 23.8 0.3 4.5e-05 23.8 0.2 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MoCF_biosynth PF00994.19 CCM05626.1 - 8.6e-34 116.0 0.0 1.4e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MCM PF00493.18 CCM05627.1 - 1.4e-135 451.3 0.0 2e-135 450.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCM05627.1 - 3.9e-22 78.9 0.1 1.9e-21 76.7 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 CCM05627.1 - 2e-08 34.0 0.0 6.6e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCM05627.1 - 7.5e-08 31.7 0.2 4.5e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCM05627.1 - 0.00015 21.3 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCM05627.1 - 0.0015 18.0 0.1 0.97 8.8 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain GTP1_OBG PF01018.17 CCM05628.1 - 6.8e-36 123.2 0.6 5.1e-25 87.9 0.1 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CCM05628.1 - 1.7e-16 60.2 0.0 4.7e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCM05628.1 - 0.00022 21.0 0.0 0.00086 19.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin family AAA_17 PF13207.1 CCM05628.1 - 0.002 18.9 1.9 0.2 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 CCM05628.1 - 0.0033 16.7 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.22 CCM05628.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 ABC transporter cobW PF02492.14 CCM05628.1 - 0.0055 16.1 0.2 0.71 9.2 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 CCM05628.1 - 0.0079 15.4 0.2 0.74 9.0 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CCM05628.1 - 0.0081 16.6 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CCM05628.1 - 0.0089 15.4 0.1 3.6 6.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCM05628.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 CCM05628.1 - 0.083 13.2 0.0 0.083 13.2 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_21 PF13304.1 CCM05628.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CCM05628.1 - 0.26 10.0 1.5 0.75 8.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein EphA2_TM PF14575.1 CCM05629.1 - 0.045 14.1 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HLH PF00010.21 CCM05630.1 - 5.9e-05 22.6 0.2 0.00012 21.6 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_S24 PF00717.18 CCM05631.1 - 1.2e-08 34.4 0.0 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Transp_cyt_pur PF02133.10 CCM05632.1 - 2e-30 105.7 33.9 9.2e-30 103.5 23.5 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 CCM05633.1 - 2.4e-35 121.9 30.8 8.6e-35 120.1 21.3 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 CCM05634.1 - 7.6e-16 57.7 0.0 1.3e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM05634.1 - 6.9e-06 25.8 9.1 1.1e-05 25.1 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FHA PF00498.21 CCM05638.1 - 2.6e-08 33.8 0.0 7.5e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 FHA domain GCP5-Mod21 PF14609.1 CCM05638.1 - 8.1 4.4 4.4 12 3.8 3.1 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Usp PF00582.21 CCM05639.1 - 1.3e-09 38.4 0.0 1.8e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family WW PF00397.21 CCM05640.1 - 5.1e-06 26.2 6.7 1.5e-05 24.6 4.6 1.9 1 0 0 1 1 1 1 WW domain Nop53 PF07767.6 CCM05641.1 - 3.3e-71 240.3 15.9 1.4e-70 238.2 11.0 1.8 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BHD_2 PF10404.4 CCM05641.1 - 6 7.2 7.5 1.9 8.8 2.2 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 PAS_8 PF13188.1 CCM05642.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 PAS domain Pribosyltran PF00156.22 CCM05643.1 - 5e-15 55.3 0.1 6.8e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCM05643.1 - 0.041 13.0 0.0 0.066 12.4 0.0 1.4 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.15 CCM05644.1 - 9.6e-127 423.3 0.0 1.3e-126 422.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 CCM05644.1 - 3.1e-09 36.4 0.1 6.4e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.7 CCM05645.1 - 1.4e-14 53.5 4.6 2.4e-07 30.4 0.2 3.1 2 1 1 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.2 CCM05645.1 - 0.89 9.4 4.2 5.1 7.0 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon ORC6 PF05460.8 CCM05645.1 - 0.9 8.5 7.5 1.1 8.2 5.2 1.3 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-ribbon_3 PF13248.1 CCM05645.1 - 2.2 7.5 5.1 14 5.0 0.8 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DUF4658 PF15555.1 CCM05646.1 - 0.31 10.9 3.4 1.6 8.6 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Sterile PF03015.14 CCM05648.1 - 0.018 15.2 0.7 0.03 14.6 0.1 1.6 2 0 0 2 2 2 0 Male sterility protein Ribonuclease_3 PF00636.21 CCM05650.1 - 4.1e-42 143.2 0.0 8.7e-21 74.4 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCM05650.1 - 7.4e-25 87.3 0.0 4.7e-10 39.5 0.0 4.4 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.9 CCM05650.1 - 3.1e-09 36.5 0.0 8.2e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain PAZ PF02170.17 CCM05650.1 - 0.00021 20.6 0.0 0.0005 19.3 0.0 1.7 1 0 0 1 1 1 1 PAZ domain Helicase_C PF00271.26 CCM05650.1 - 0.053 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain COX7C PF02935.11 CCM05651.1 - 7.4e-12 44.8 0.2 9e-12 44.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc MFS_1 PF07690.11 CCM05652.1 - 3.9e-09 35.6 16.4 4.2e-09 35.6 8.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF202 PF02656.10 CCM05652.1 - 4.9 7.4 7.5 2.4 8.4 1.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF202) MFS_1 PF07690.11 CCM05653.1 - 9.8e-65 218.5 58.3 3.5e-39 134.5 22.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 CCM05655.1 - 4.2e-19 68.6 0.3 1.2e-09 38.4 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCM05655.1 - 2.1e-18 65.1 0.3 7.3e-09 35.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CCM05655.1 - 5.1e-15 55.5 0.5 1.6e-09 38.0 0.0 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCM05655.1 - 2e-14 53.2 0.1 2.9e-06 27.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM05655.1 - 1.5e-12 46.3 0.3 0.00057 19.8 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 CCM05655.1 - 0.00032 20.2 0.1 0.0016 18.0 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain DUF3122 PF11320.3 CCM05655.1 - 0.038 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) Tup_N PF08581.5 CCM05655.1 - 0.42 10.8 3.8 8 6.7 0.1 2.7 2 1 0 2 2 2 0 Tup N-terminal DUF972 PF06156.8 CCM05655.1 - 0.97 9.8 2.9 17 5.7 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DSPn PF14671.1 CCM05656.1 - 1.5e-39 135.1 0.0 6.7e-38 129.8 0.0 2.7 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CCM05656.1 - 1.9e-15 56.6 0.0 4.4e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCM05656.1 - 8.5e-06 25.2 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCM05656.1 - 0.00034 20.6 0.0 0.00058 19.9 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CCM05656.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family URO-D PF01208.12 CCM05657.1 - 1.1e-125 419.1 0.0 1.2e-125 418.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TT_ORF2a PF08197.6 CCM05657.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 pORF2a truncated protein COMPASS-Shg1 PF05205.7 CCM05658.1 - 1.8e-11 44.2 0.7 2.4e-11 43.8 0.1 1.7 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 MFS_1 PF07690.11 CCM05660.1 - 1e-30 106.6 28.5 1.6e-30 106.0 19.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Chitin_synth_2 PF03142.10 CCM05660.1 - 0.058 11.7 0.8 0.093 11.1 0.6 1.2 1 0 0 1 1 1 0 Chitin synthase DUF4231 PF14015.1 CCM05660.1 - 3.7 7.5 8.4 2.5 8.1 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Mod_r PF07200.8 CCM05661.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein EAF PF09816.4 CCM05662.1 - 1.2e-18 67.0 0.0 2.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Pkinase PF00069.20 CCM05665.1 - 9.6e-70 234.6 0.0 1.6e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05665.1 - 1.1e-31 109.8 0.0 4.4e-30 104.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM05665.1 - 8.3e-05 21.6 1.9 0.72 8.7 0.3 3.4 3 1 0 3 3 3 2 Kinase-like RIO1 PF01163.17 CCM05665.1 - 0.00012 21.4 0.8 0.00021 20.6 0.5 1.3 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 CCM05665.1 - 0.055 12.2 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RicinB_lectin_2 PF14200.1 CCM05666.1 - 0.001 19.3 0.0 0.0018 18.6 0.0 1.4 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Kinesin PF00225.18 CCM05667.1 - 5.4e-108 360.6 0.0 9.6e-108 359.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 CCM05667.1 - 5.9e-40 136.1 0.1 1.7e-39 134.7 0.0 1.9 2 0 0 2 2 2 1 Kinesin protein PH PF00169.24 CCM05667.1 - 1.4e-11 44.4 0.1 8.9e-11 41.9 0.0 2.4 3 0 0 3 3 3 1 PH domain KIF1B PF12423.3 CCM05667.1 - 5.3e-07 29.5 0.6 1.3e-06 28.3 0.4 1.7 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 CCM05667.1 - 8.3e-07 29.0 0.0 6.2e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.1 CCM05667.1 - 0.037 14.2 0.2 2.2 8.5 0.0 3.6 3 0 0 3 3 3 0 Pleckstrin homology domain Ribosomal_S4 PF00163.14 CCM05668.1 - 2e-12 47.2 0.3 3e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCM05668.1 - 2.2e-12 46.1 0.0 3.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain PaaB PF06243.6 CCM05668.1 - 0.018 15.1 0.2 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Phenylacetic acid degradation B Fe-ADH PF00465.14 CCM05669.1 - 2.1e-55 187.8 2.1 2.7e-55 187.4 1.5 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CCM05669.1 - 1.1e-33 116.6 0.1 1.4e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 CCM05669.1 - 5.7e-05 22.1 0.9 0.057 12.3 0.1 2.2 2 0 0 2 2 2 2 3-dehydroquinate synthase Big_2 PF02368.13 CCM05669.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) PHD PF00628.24 CCM05670.1 - 6e-08 32.2 10.8 1.2e-07 31.3 7.5 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 CCM05670.1 - 0.0025 18.1 0.0 0.011 16.0 0.0 2.1 1 0 0 1 1 1 1 SET domain PHD_2 PF13831.1 CCM05670.1 - 0.0082 15.4 10.2 0.019 14.2 7.1 1.6 1 0 0 1 1 1 1 PHD-finger DUF1423 PF07227.6 CCM05670.1 - 0.042 12.4 1.5 0.074 11.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Trypsin_2 PF13365.1 CCM05671.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 CCM05671.1 - 0.05 12.5 0.2 0.16 10.9 0.1 1.7 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Aconitase PF00330.15 CCM05672.1 - 7.4e-177 588.4 0.6 1.7e-176 587.3 0.4 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCM05672.1 - 1.2e-46 158.1 0.0 2.2e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Sld5 PF05916.6 CCM05675.1 - 0.00063 20.0 0.0 0.00096 19.4 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein ThiF PF00899.16 CCM05676.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CCM05676.1 - 0.014 14.9 0.0 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 MoeZ/MoeB domain LysM PF01476.15 CCM05677.1 - 2.4e-15 56.1 0.3 4.8e-07 29.5 0.1 2.2 2 0 0 2 2 2 2 LysM domain MSP1_C PF07462.6 CCM05677.1 - 3.2 6.0 5.0 4.3 5.6 3.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus p450 PF00067.17 CCM05680.1 - 1.3e-14 53.5 0.0 1.4e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM05681.1 - 2.5e-07 29.5 0.0 2.9e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.16 CCM05682.1 - 1.9e-42 145.0 0.0 2.2e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cir_N PF10197.4 CCM05683.1 - 0.00038 20.3 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR Barttin PF15462.1 CCM05684.1 - 0.25 10.9 1.3 0.42 10.2 0.8 1.4 1 1 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) FPN1 PF06963.7 CCM05685.1 - 3.9e-123 411.0 15.2 4.7e-123 410.7 10.5 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF218 PF02698.12 CCM05685.1 - 8.8e-06 25.2 0.0 2.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 DUF218 domain Hydrolase_6 PF13344.1 CCM05686.1 - 3e-24 84.8 0.0 5.6e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCM05686.1 - 2.6e-21 75.1 0.0 1.2e-20 72.9 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 CCM05686.1 - 0.00016 21.9 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCM05686.1 - 0.00033 21.1 0.0 0.009 16.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 CCM05687.1 - 5.4e-22 77.9 0.1 5.6e-11 42.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCM05687.1 - 2.2e-19 68.2 4.2 6.5e-08 32.0 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CCM05687.1 - 2.3e-16 59.4 2.8 5.6e-09 35.9 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCM05687.1 - 9.3e-15 54.6 1.1 3.5e-07 30.5 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM05687.1 - 1.2e-14 52.8 0.8 0.00042 20.2 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Spc42p PF11544.3 CCM05687.1 - 0.18 11.7 0.2 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Spindle pole body component Spc42p Fungal_trans PF04082.13 CCM05688.1 - 5.9e-16 58.1 0.6 1e-15 57.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 CCM05688.1 - 1.7e-05 24.8 7.3 0.0019 18.3 1.7 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCM05688.1 - 4.6e-05 23.4 2.9 4.6e-05 23.4 2.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM05688.1 - 0.0037 17.5 2.7 0.0037 17.5 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF563 PF04577.9 CCM05689.1 - 9.8e-22 77.8 0.9 1.3e-20 74.2 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF563) DUF2062 PF09835.4 CCM05691.1 - 0.078 12.5 0.1 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) MPC PF03650.8 CCM05692.1 - 2e-40 137.4 0.1 2.4e-40 137.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Lysis_S PF04971.7 CCM05693.1 - 1.8 8.3 5.2 0.43 10.3 0.8 2.0 2 1 0 2 2 2 0 Lysis protein S Sugar_tr PF00083.19 CCM05695.1 - 2.4e-81 273.6 27.4 1.7e-80 270.7 19.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM05695.1 - 8.2e-09 34.6 44.4 2.1e-08 33.2 21.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP_synth_reg PF14960.1 CCM05695.1 - 0.97 8.6 3.1 9.9 5.4 0.0 2.9 2 0 0 2 2 2 0 ATP synthase regulation WD40 PF00400.27 CCM05696.1 - 3e-17 61.7 2.4 0.00012 21.7 0.0 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleos_tra2_C PF07662.8 CCM05697.1 - 2e-64 216.9 7.3 2e-64 216.9 5.1 1.8 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CCM05697.1 - 3.1e-16 59.4 5.8 3.1e-16 59.4 4.0 4.3 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus DUF1771 PF08590.5 CCM05698.1 - 2.5e-18 65.8 7.0 2.5e-18 65.8 4.8 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1771) Smr PF01713.16 CCM05698.1 - 5.9e-15 55.2 0.1 1.7e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Smr domain DnaJ PF00226.26 CCM05698.1 - 0.00049 19.7 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain ODC_AZ PF02100.12 CCM05700.1 - 1.3e-17 63.2 0.0 2.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribosomal_S5 PF00333.15 CCM05701.1 - 9.7e-28 95.7 1.5 9.7e-28 95.7 1.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CCM05701.1 - 1.7e-21 75.2 0.0 2.9e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Na_H_Exchanger PF00999.16 CCM05702.1 - 5.9e-52 176.4 16.3 1.1e-51 175.5 11.3 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Sigma_1_2 PF03084.9 CCM05703.1 - 0.087 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family RRM_1 PF00076.17 CCM05704.1 - 1.9e-12 46.6 0.1 4.9e-05 22.8 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM05704.1 - 7.2e-11 41.9 0.0 0.00017 21.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM05704.1 - 3.9e-05 23.4 0.1 0.00046 19.9 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.22 CCM05705.1 - 1.8e-29 102.9 0.0 4.6e-29 101.5 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Asp PF00026.18 CCM05706.1 - 3.2e-23 82.4 0.1 3.1e-22 79.2 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCM05706.1 - 0.001 19.5 0.1 0.94 10.0 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease 7TM_GPCR_Srd PF10317.4 CCM05706.1 - 0.043 12.8 0.1 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd SLAC1 PF03595.12 CCM05707.1 - 1.5e-52 178.2 42.7 1.8e-52 178.0 29.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Peptidase_A22B PF04258.8 CCM05708.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase HCV_NS4a PF01006.15 CCM05708.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.6 1 1 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Asp PF00026.18 CCM05709.1 - 4.1e-74 249.6 8.4 4.8e-74 249.4 5.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM05709.1 - 2.4e-07 30.8 0.8 5.1e-07 29.7 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCM05709.1 - 0.0025 17.4 0.4 0.027 14.0 0.2 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal GATA PF00320.22 CCM05710.1 - 1.2e-18 66.1 2.3 2.5e-18 65.1 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CCM05710.1 - 2.8e-13 49.1 1.6 5.8e-13 48.1 1.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Sec7 PF01369.15 CCM05711.1 - 1.8e-37 128.8 0.0 3.3e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CCM05711.1 - 4.1e-28 97.9 0.0 9.6e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Lzipper-MIP1 PF14389.1 CCM05711.1 - 0.00076 19.5 0.9 0.0025 17.8 0.6 1.9 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 PH PF00169.24 CCM05711.1 - 0.052 13.7 0.0 0.23 11.6 0.0 2.1 1 1 0 1 1 1 0 PH domain CBF_beta PF02312.12 CCM05713.1 - 0.016 14.8 0.0 0.018 14.6 0.0 1.0 1 0 0 1 1 1 0 Core binding factor beta subunit CsoSCA PF08936.5 CCM05713.1 - 0.058 11.7 0.0 0.058 11.7 0.0 1.0 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase CDC27 PF09507.5 CCM05714.1 - 2 7.5 13.8 3.4 6.7 9.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SOG2 PF10428.4 CCM05714.1 - 2.8 6.5 11.1 2.7 6.5 7.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF605 PF04652.11 CCM05714.1 - 4.3 6.6 22.4 5.6 6.2 15.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 CCM05714.1 - 7.8 5.9 13.5 10 5.5 9.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) CPSF73-100_C PF11718.3 CCM05716.1 - 1.2e-56 191.5 0.0 1.8e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CCM05716.1 - 1.1e-30 106.1 0.0 3.7e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CCM05716.1 - 5.4e-13 49.0 0.3 5.4e-13 49.0 0.2 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 CCM05716.1 - 5e-11 42.2 0.2 1.1e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CCM05716.1 - 9.3e-09 35.1 0.4 9.3e-09 35.1 0.3 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CCM05716.1 - 1.6e-06 27.8 0.0 1e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain G_glu_transpept PF01019.16 CCM05719.1 - 3.1e-136 454.8 0.0 3.7e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.13 CCM05720.1 - 2e-25 89.5 2.3 2.8e-25 89.0 1.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 CCM05720.1 - 0.003 17.9 0.0 0.0065 16.8 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 CCM05720.1 - 0.0076 15.1 0.0 0.026 13.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 CCM05720.1 - 0.044 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase Beta_propel PF09826.4 CCM05720.1 - 0.082 11.2 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Beta propeller domain Aminotran_4 PF01063.14 CCM05721.1 - 1.9e-20 73.3 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Lactamase_B PF00753.22 CCM05721.1 - 7.5e-20 71.4 2.4 1.2e-19 70.6 0.9 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCM05721.1 - 0.0097 15.4 0.3 0.016 14.7 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Inhibitor_I9 PF05922.11 CCM05723.1 - 0.0003 21.2 0.0 0.00057 20.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ifi-6-16 PF06140.8 CCM05725.1 - 1.6e-07 30.9 13.8 2.6e-07 30.3 9.6 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family IMPDH PF00478.20 CCM05726.1 - 2.6e-133 444.3 0.0 6e-133 443.0 0.0 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CCM05726.1 - 8.2e-19 67.1 0.1 2.3e-08 33.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 CCM05726.1 - 3.3e-11 42.6 1.4 7.2e-11 41.5 1.0 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 CCM05726.1 - 2.9e-09 36.5 4.2 1.1e-06 28.0 2.8 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 CCM05726.1 - 0.00012 21.4 2.3 0.00051 19.3 0.6 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 CCM05726.1 - 0.0032 16.5 0.9 0.0061 15.6 0.6 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Abhydrolase_6 PF12697.2 CCM05727.1 - 1.8e-22 80.3 0.3 2.4e-22 79.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM05727.1 - 3.2e-14 53.0 0.0 6.4e-14 52.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM05727.1 - 5.6e-06 26.1 0.0 8.4e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 CCM05727.1 - 0.069 13.0 0.2 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Epoxide hydrolase N terminus PNP_UDP_1 PF01048.15 CCM05730.1 - 9.6e-35 119.6 0.1 1.9e-34 118.6 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily SH3_2 PF07653.12 CCM05731.1 - 0.00021 20.7 0.0 0.00044 19.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCM05731.1 - 0.00054 19.2 0.0 0.00097 18.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCM05731.1 - 0.0009 18.7 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 CCM05733.1 - 8.4e-63 211.9 0.0 1.5e-62 211.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05733.1 - 3e-38 131.3 0.0 4.3e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM05733.1 - 3.9e-07 29.3 0.0 1.6e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCM05733.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1395 PF07160.7 CCM05733.1 - 0.039 13.4 3.5 0.061 12.8 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) APH PF01636.18 CCM05733.1 - 0.055 13.2 0.2 2 8.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family 2-Hacid_dh_C PF02826.14 CCM05734.1 - 2.9e-47 160.0 0.0 4.8e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCM05734.1 - 8.8e-20 70.5 0.0 1.3e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCM05734.1 - 8.1e-05 22.5 0.0 0.00026 20.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.14 CCM05734.1 - 0.011 14.8 0.4 2.7 7.0 0.1 2.4 1 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GFO_IDH_MocA PF01408.17 CCM05734.1 - 0.021 15.3 0.0 0.069 13.6 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.1 CCM05734.1 - 0.079 13.2 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.12 CCM05734.1 - 0.081 13.3 0.1 0.45 10.9 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 CCM05735.1 - 1.1e-68 231.1 0.0 1.8e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05735.1 - 5.5e-48 163.2 0.0 1e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Syntaxin_2 PF14523.1 CCM05735.1 - 4.9e-20 71.4 2.2 4.9e-20 71.4 1.5 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 CCM05735.1 - 1.1e-16 60.2 0.6 3.4e-16 58.6 0.4 2.0 1 0 0 1 1 1 1 SNARE domain Ribosomal_L5_C PF00673.16 CCM05735.1 - 1.5e-12 47.0 0.0 3.8e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Kinase-like PF14531.1 CCM05735.1 - 0.00048 19.1 0.0 0.0025 16.8 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Peptidase_M64 PF09471.5 CCM05737.1 - 5.5e-27 95.0 0.0 8.1e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 ADH_zinc_N PF00107.21 CCM05738.1 - 6.7e-28 96.8 0.2 1.2e-27 96.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM05738.1 - 1.3e-16 61.6 0.5 3e-16 60.4 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM05738.1 - 9.3e-13 47.8 0.1 2.8e-11 43.1 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain HupF_HypC PF01455.13 CCM05738.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 HupF/HypC family RPAP1_C PF08620.5 CCM05739.1 - 2e-18 66.0 0.0 3.9e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CCM05739.1 - 1.3e-10 40.6 8.0 2.4e-10 39.8 5.5 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal Methyltransf_26 PF13659.1 CCM05740.1 - 2.6e-12 46.7 0.1 2.2e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CCM05740.1 - 1.7e-11 43.9 0.0 3.6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCM05740.1 - 2.7e-11 43.1 0.1 5.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCM05740.1 - 8e-11 42.5 0.1 1.1e-09 38.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM05740.1 - 2.7e-10 40.5 0.0 1.2e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM05740.1 - 2.9e-08 33.6 0.0 6.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCM05740.1 - 2.6e-07 30.1 0.0 4.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CCM05740.1 - 1.3e-06 28.7 0.0 1.4e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM05740.1 - 1.4e-06 28.5 0.0 8.8e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 CCM05740.1 - 4.7e-06 26.3 0.1 8.7e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.11 CCM05740.1 - 0.00059 18.8 0.0 0.00099 18.1 0.0 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TehB PF03848.9 CCM05740.1 - 0.0014 17.8 0.0 0.0025 17.0 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 CCM05740.1 - 0.0027 16.4 0.0 0.0039 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 CCM05740.1 - 0.0028 17.6 0.1 0.0088 16.0 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Cons_hypoth95 PF03602.10 CCM05740.1 - 0.003 16.9 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.1 CCM05740.1 - 0.0087 16.8 0.1 0.027 15.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 CCM05740.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 CCM05740.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 CCM05740.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 CCM05740.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 CCM05741.1 - 2e-26 92.9 1.2 2.5e-26 92.5 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM05741.1 - 5e-10 39.5 0.0 7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM05741.1 - 1.3e-07 31.4 0.5 2e-07 30.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCM05741.1 - 0.014 15.1 0.3 0.027 14.2 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase WD40 PF00400.27 CCM05742.1 - 4.4e-18 64.4 2.2 8.8e-09 34.9 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.7 CCM05742.1 - 4.3e-05 23.2 0.1 0.00016 21.3 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CCM05742.1 - 0.00011 22.2 0.1 0.00035 20.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 CCM05742.1 - 0.0025 16.6 0.0 0.0088 14.9 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 CCM05742.1 - 0.0036 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Nucleoporin_N PF08801.6 CCM05742.1 - 0.0085 14.8 1.1 1 7.9 0.0 2.2 1 1 1 2 2 2 2 Nup133 N terminal like Arch_ATPase PF01637.13 CCM05742.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 CCM05742.1 - 0.026 14.7 0.0 0.1 12.7 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RicinB_lectin_2 PF14200.1 CCM05742.1 - 0.078 13.3 0.1 0.65 10.3 0.0 2.4 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Pyr_redox_3 PF13738.1 CCM05743.1 - 3.1e-24 86.1 0.0 9.5e-24 84.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCM05743.1 - 7.8e-15 54.0 0.1 1.1e-13 50.2 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CCM05743.1 - 6.2e-14 52.3 0.0 1.6e-08 34.7 0.0 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM05743.1 - 3.5e-12 45.9 0.2 2.3e-10 39.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 CCM05743.1 - 4.9e-11 42.8 2.9 0.0012 19.1 0.3 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCM05743.1 - 2.5e-08 33.8 0.4 2.3e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCM05743.1 - 1.5e-07 30.6 1.2 0.0061 15.5 0.0 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCM05743.1 - 3.8e-07 29.4 0.2 3.4e-05 23.0 0.2 2.9 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 CCM05743.1 - 7.9e-05 21.2 0.3 0.02 13.3 0.1 2.9 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_9 PF13454.1 CCM05743.1 - 0.00034 20.4 1.8 0.75 9.5 0.1 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CCM05743.1 - 0.00059 18.7 3.0 0.012 14.4 1.0 3.0 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 CCM05743.1 - 0.0012 18.0 0.1 0.11 11.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SnoaL_2 PF12680.2 CCM05743.1 - 0.005 17.2 0.9 0.16 12.3 0.1 2.6 2 0 0 2 2 2 1 SnoaL-like domain Amino_oxidase PF01593.19 CCM05743.1 - 0.005 15.9 3.6 0.053 12.5 0.3 3.0 4 0 0 4 4 4 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 CCM05743.1 - 0.015 14.3 0.2 1.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 CCM05743.1 - 0.02 13.8 0.5 0.37 9.6 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein SnoaL_3 PF13474.1 CCM05743.1 - 0.027 14.5 0.1 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 CCM05743.1 - 0.029 14.5 0.6 0.077 13.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) 3HCDH_N PF02737.13 CCM05743.1 - 0.05 13.2 0.5 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 CCM05743.1 - 0.24 10.4 6.5 0.083 11.9 0.6 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 CCM05743.1 - 0.38 9.5 3.6 0.83 8.4 0.3 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A ABC_tran PF00005.22 CCM05744.1 - 6.4e-47 159.2 0.0 5.6e-28 97.9 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCM05744.1 - 4.4e-43 147.6 25.4 8.3e-22 77.8 5.5 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 CCM05744.1 - 2.1e-11 44.3 1.2 0.092 12.6 0.1 4.3 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 CCM05744.1 - 6.4e-10 38.6 5.7 0.023 13.9 0.3 4.3 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CCM05744.1 - 6e-08 32.3 0.1 0.0088 15.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CCM05744.1 - 2.5e-06 27.5 2.2 0.0011 18.9 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CCM05744.1 - 6.1e-06 25.6 0.1 0.088 12.3 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CCM05744.1 - 9.9e-05 22.7 9.7 0.028 14.7 3.8 3.5 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 CCM05744.1 - 0.00014 21.8 0.1 0.2 11.5 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CCM05744.1 - 0.00015 21.3 0.4 0.14 11.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 CCM05744.1 - 0.00027 21.0 1.2 0.53 10.4 0.6 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCM05744.1 - 0.00028 21.6 0.0 1.8 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CCM05744.1 - 0.0012 19.3 0.2 2.3 8.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 CCM05744.1 - 0.0013 17.6 0.2 0.87 8.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Adeno_IVa2 PF02456.10 CCM05744.1 - 0.0014 17.3 0.0 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein MobB PF03205.9 CCM05744.1 - 0.0015 18.2 0.5 0.61 9.7 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCM05744.1 - 0.0021 18.3 0.1 4.2 7.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 CCM05744.1 - 0.0026 17.6 0.7 0.063 13.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 CCM05744.1 - 0.0049 15.9 0.0 0.27 10.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 CCM05744.1 - 0.0056 15.8 0.3 2.6 7.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCM05744.1 - 0.0058 16.1 2.3 3.6 6.9 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain IstB_IS21 PF01695.12 CCM05744.1 - 0.0095 15.3 0.3 6.7 6.0 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein ResIII PF04851.10 CCM05744.1 - 0.027 14.2 0.0 4.9 6.9 0.0 2.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CCM05744.1 - 0.039 13.6 0.0 9.1 5.9 0.0 2.9 2 1 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 CCM05744.1 - 0.059 13.0 0.4 23 4.6 0.0 3.5 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 CCM05744.1 - 0.56 10.0 5.6 5.4 6.8 0.0 3.5 4 0 0 4 4 4 0 Dynamin family 2OG-FeII_Oxy PF03171.15 CCM05745.1 - 6.2e-22 77.7 0.0 8.7e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CCM05745.1 - 2.3e-05 24.9 0.0 4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AA_permease_2 PF13520.1 CCM05746.1 - 3.9e-60 203.5 49.4 4.6e-60 203.3 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCM05746.1 - 1.1e-19 70.1 44.6 1.5e-19 69.6 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 CCM05747.1 - 2e-64 217.8 0.0 7.4e-64 215.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.23 CCM05748.1 - 1.1e-30 106.5 0.0 1.8e-30 105.8 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCM05748.1 - 3.3e-08 33.2 0.0 5.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain ELFV_dehydrog PF00208.16 CCM05749.1 - 1.4e-48 165.6 0.0 1.9e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CCM05749.1 - 4.7e-19 67.4 0.0 3.4e-13 48.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 CCM05749.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TTSSLRR PF12468.3 CCM05752.1 - 0.0019 17.6 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Type III secretion system leucine rich repeat protein Aminotran_5 PF00266.14 CCM05754.1 - 3.6e-31 108.2 0.0 3e-30 105.2 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCM05754.1 - 0.0068 15.5 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2795 PF11387.3 CCM05754.1 - 0.081 12.8 0.1 6.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) SelP_N PF04592.9 CCM05754.1 - 0.33 10.2 7.6 0.61 9.4 5.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region IKI3 PF04762.7 CCM05755.1 - 1.5e-235 784.2 0.0 3.9e-233 776.2 0.0 2.1 1 1 0 1 1 1 1 IKI3 family Clathrin PF00637.15 CCM05755.1 - 0.03 13.9 1.2 1.6 8.2 0.1 3.2 2 1 1 3 3 3 0 Region in Clathrin and VPS DUF4602 PF15375.1 CCM05755.1 - 0.037 14.0 0.3 0.075 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) Apolipoprotein PF01442.13 CCM05755.1 - 0.57 9.6 7.6 0.52 9.7 0.6 3.0 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain RVT_thumb PF06817.9 CCM05756.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase thumb domain CBM_21 PF03370.8 CCM05758.1 - 5.3e-31 106.9 0.1 9.5e-31 106.1 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit ChitinaseA_N PF08329.5 CCM05758.1 - 0.14 11.9 0.2 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Pkinase PF00069.20 CCM05759.1 - 7.1e-49 166.2 0.0 1.3e-47 162.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05759.1 - 3.1e-26 92.0 0.0 2.8e-25 88.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM05759.1 - 0.0069 15.3 0.0 0.018 14.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCM05759.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC2_membrane PF01061.19 CCM05760.1 - 1.6e-35 122.1 20.4 1.6e-35 122.1 14.2 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CCM05760.1 - 2.5e-22 79.6 0.0 5.4e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CCM05760.1 - 0.00045 19.3 23.0 0.00045 19.3 15.9 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein SbcCD_C PF13558.1 CCM05760.1 - 0.17 11.8 0.1 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 CCM05760.1 - 0.25 11.2 0.1 2.2 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain hEGF PF12661.2 CCM05760.1 - 3.7 7.8 20.1 2.5 8.3 3.8 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF RNA_polI_A34 PF08208.6 CCM05761.1 - 1.2e-12 47.9 2.7 3.5e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Ada3 PF10198.4 CCM05762.1 - 1e-22 80.2 0.1 1e-22 80.2 0.1 2.9 4 0 0 4 4 4 1 Histone acetyltransferases subunit 3 Rrn6 PF10214.4 CCM05762.1 - 4.2 5.3 11.1 7.5 4.5 7.7 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MgtE PF01769.11 CCM05763.1 - 8.6e-21 74.6 25.3 8.7e-12 45.4 4.1 3.9 3 1 1 4 4 4 3 Divalent cation transporter Hist_deacetyl PF00850.14 CCM05764.1 - 2e-80 270.3 0.3 2.9e-80 269.8 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RAP1 PF07218.6 CCM05764.1 - 9 4.2 5.5 13 3.7 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Per1 PF04080.8 CCM05765.1 - 1.8e-94 316.1 6.6 2.5e-94 315.6 4.6 1.2 1 0 0 1 1 1 1 Per1-like Pribosyltran_N PF13793.1 CCM05766.1 - 7.1e-48 161.1 0.4 2.5e-47 159.3 0.1 2.1 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCM05766.1 - 3.3e-36 124.7 0.3 2.8e-31 108.6 0.1 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCM05766.1 - 1.6e-10 40.7 0.7 7.9e-10 38.5 0.3 2.2 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCM05766.1 - 0.0039 16.4 0.1 0.0066 15.6 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase OCD_Mu_crystall PF02423.10 CCM05766.1 - 0.052 12.3 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family AA_kinase PF00696.23 CCM05767.1 - 3.7e-41 141.2 1.5 5.2e-41 140.7 1.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CCM05767.1 - 1.8e-12 46.8 1.0 1.4e-05 24.7 0.1 2.7 3 0 0 3 3 3 2 PUA domain DOPA_dioxygen PF08883.6 CCM05768.1 - 1.5e-06 28.1 0.0 0.0017 18.4 0.0 2.2 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family YtxH PF12732.2 CCM05769.1 - 0.025 14.9 0.4 0.077 13.3 0.0 2.0 2 0 0 2 2 2 0 YtxH-like protein HET PF06985.6 CCM05770.1 - 5.6e-18 65.4 2.1 7e-15 55.4 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ADK PF00406.17 CCM05771.1 - 1.1e-58 197.3 0.1 4.7e-58 195.3 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase ADK_lid PF05191.9 CCM05771.1 - 3.4e-14 52.2 0.0 9.1e-14 50.8 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid Fungal_trans PF04082.13 CCM05771.1 - 7.2e-13 48.0 0.4 1.4e-12 47.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM05771.1 - 0.00013 21.8 3.2 0.0003 20.6 2.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_33 PF13671.1 CCM05771.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CCM05771.1 - 0.013 16.2 0.0 0.044 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain FlxA PF14282.1 CCM05771.1 - 0.036 14.0 0.2 0.036 14.0 0.2 2.7 3 0 0 3 3 2 0 FlxA-like protein Zeta_toxin PF06414.7 CCM05771.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Copper-fist PF00649.13 CCM05771.1 - 0.12 11.6 1.0 0.27 10.4 0.7 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain Not3 PF04065.10 CCM05771.1 - 0.23 10.6 0.8 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Allexi_40kDa PF05549.6 CCM05771.1 - 0.57 9.4 3.7 0.19 11.0 0.4 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein DDOST_48kD PF03345.9 CCM05772.1 - 2.6e-105 352.4 0.0 2.9e-105 352.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta V_ATPase_I PF01496.14 CCM05773.1 - 1.9e-276 918.8 0.0 2.2e-276 918.6 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ABC_tran PF00005.22 CCM05774.1 - 4.4e-43 146.8 0.0 1.4e-20 73.9 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCM05774.1 - 1.5e-15 57.9 3.3 1.8e-06 28.1 0.2 3.9 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 CCM05774.1 - 6.9e-13 48.3 0.3 0.0021 17.3 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCM05774.1 - 1.8e-08 33.7 0.2 0.0073 15.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_2 PF13646.1 CCM05774.1 - 3.3e-07 30.4 16.0 0.0002 21.5 0.1 4.6 3 1 2 5 5 4 3 HEAT repeats AAA_16 PF13191.1 CCM05774.1 - 8.6e-07 29.1 1.8 0.0092 15.9 0.0 4.4 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 CCM05774.1 - 1.3e-06 28.5 0.0 0.027 14.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CCM05774.1 - 1.5e-06 29.0 0.2 0.01 16.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CCM05774.1 - 3.7e-06 26.7 0.0 0.019 14.8 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CCM05774.1 - 4.3e-06 26.7 0.0 0.0028 17.4 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 Miro PF08477.8 CCM05774.1 - 3.1e-05 24.4 0.1 0.22 11.9 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 CCM05774.1 - 3.2e-05 23.5 0.2 0.047 13.1 0.1 2.9 3 0 0 3 3 2 2 AAA-like domain MMR_HSR1 PF01926.18 CCM05774.1 - 3.4e-05 23.7 0.0 0.093 12.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 CCM05774.1 - 3.5e-05 24.1 2.6 0.0057 16.9 0.1 3.2 4 0 0 4 4 2 1 AAA domain Chromo PF00385.19 CCM05774.1 - 4.4e-05 23.0 0.1 0.00011 21.8 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.7 CCM05774.1 - 6.2e-05 22.7 0.1 0.23 11.1 0.0 2.8 3 0 0 3 3 2 2 NACHT domain DUF258 PF03193.11 CCM05774.1 - 6.7e-05 22.1 0.0 0.079 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 CCM05774.1 - 0.00011 21.9 0.0 0.25 11.0 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CCM05774.1 - 0.00012 22.2 0.0 0.3 11.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 CCM05774.1 - 0.00016 21.8 0.0 2.8 8.1 0.0 4.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCM05774.1 - 0.00038 19.9 0.0 2 7.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain Arch_ATPase PF01637.13 CCM05774.1 - 0.00046 19.9 0.1 2.7 7.6 0.0 3.6 3 0 0 3 3 3 1 Archaeal ATPase HEAT_EZ PF13513.1 CCM05774.1 - 0.00046 20.5 12.0 0.49 10.9 0.2 5.3 3 2 2 5 5 5 2 HEAT-like repeat AAA_33 PF13671.1 CCM05774.1 - 0.00055 19.8 0.0 0.49 10.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 CCM05774.1 - 0.00057 19.0 0.2 0.8 8.6 0.0 3.5 2 1 0 3 3 3 1 AAA ATPase domain ArgK PF03308.11 CCM05774.1 - 0.00058 18.7 0.3 0.42 9.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein HEAT PF02985.17 CCM05774.1 - 0.00059 19.6 6.4 0.52 10.5 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat AAA_28 PF13521.1 CCM05774.1 - 0.0018 18.2 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCM05774.1 - 0.0024 17.4 0.1 0.61 9.5 0.0 2.9 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 CCM05774.1 - 0.0041 17.4 11.6 0.071 13.4 0.0 3.5 3 1 1 4 4 4 1 AAA domain KAP_NTPase PF07693.9 CCM05774.1 - 0.0055 15.7 0.2 0.023 13.7 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.1 CCM05774.1 - 0.0057 16.2 0.1 3.6 7.1 0.1 3.0 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 CCM05774.1 - 0.0087 15.0 0.1 3.2 6.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CCM05774.1 - 0.01 15.7 0.0 2.3 8.1 0.0 3.4 2 2 0 2 2 2 0 AAA domain AAA_13 PF13166.1 CCM05774.1 - 0.014 13.8 1.9 2 6.7 0.0 2.9 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 CCM05774.1 - 0.028 14.2 0.0 0.94 9.2 0.0 2.7 2 0 0 2 2 2 0 Dynamin family DUF1546 PF07571.8 CCM05774.1 - 0.048 13.7 0.1 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) NTPase_1 PF03266.10 CCM05774.1 - 0.05 13.3 0.1 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.17 CCM05774.1 - 0.067 12.0 0.5 3.4 6.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain U3snoRNP10 PF12397.3 CCM05774.1 - 0.11 12.4 2.3 0.19 11.6 0.8 2.1 2 0 0 2 2 1 0 U3 small nucleolar RNA-associated protein 10 cobW PF02492.14 CCM05774.1 - 0.11 11.9 2.4 14 5.1 0.1 3.6 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 CCM05774.1 - 0.22 11.2 4.4 14 5.4 0.1 4.2 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCM05774.1 - 0.62 9.8 5.7 1.6 8.5 0.0 3.6 4 0 0 4 4 3 0 Part of AAA domain Peptidase_M50B PF13398.1 CCM05775.1 - 9.2e-46 155.7 13.5 1.3e-45 155.2 9.4 1.2 1 0 0 1 1 1 1 Peptidase M50B-like DUF202 PF02656.10 CCM05775.1 - 0.6 10.3 12.0 25 5.1 1.3 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Ras PF00071.17 CCM05777.1 - 2.1e-56 189.8 2.2 2.4e-52 176.6 0.2 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCM05777.1 - 1.7e-15 57.5 0.2 3.6e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 CCM05777.1 - 3.2e-08 33.0 0.1 4.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM05777.1 - 3.2e-05 23.4 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCM05777.1 - 0.0029 17.5 0.5 0.012 15.5 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCM05777.1 - 0.005 16.9 0.2 0.017 15.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain DUF718 PF05336.8 CCM05778.1 - 2.6e-30 104.3 0.1 3e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) MIF4G PF02854.14 CCM05779.1 - 5.1e-29 101.1 1.5 2.3e-28 99.0 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CCM05779.1 - 4.5e-24 84.3 0.1 1e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 MA3 domain Lactamase_B PF00753.22 CCM05780.1 - 1.7e-05 24.5 0.1 2.8e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily VCBS PF13517.1 CCM05781.1 - 6.1e-26 90.5 17.0 2.3e-08 34.2 1.3 5.6 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CCM05781.1 - 7.5e-17 60.4 13.1 0.013 15.2 0.0 7.1 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 CCM05781.1 - 2.9e-07 30.1 4.1 0.92 8.9 0.0 6.1 5 1 1 6 6 6 5 Insecticide toxin TcdB middle/N-terminal region Ras PF00071.17 CCM05783.1 - 6.9e-54 181.5 0.0 8e-54 181.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM05783.1 - 2.9e-16 60.0 0.0 4.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM05783.1 - 2.1e-07 30.3 0.0 2.9e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1077 PF06417.7 CCM05784.1 - 7e-22 77.1 0.1 8.3e-22 76.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Piwi PF02171.12 CCM05785.1 - 4.2e-66 222.9 0.0 8.8e-66 221.9 0.0 1.6 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 CCM05785.1 - 5.7e-15 54.4 0.1 1.6e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 CCM05785.1 - 1.3e-05 24.5 0.0 2.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ORC2 PF04084.9 CCM05786.1 - 9.4e-67 225.1 0.0 1.1e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 HET PF06985.6 CCM05787.1 - 1.5e-24 86.7 0.0 3e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Baculo_DNA_bind PF04786.7 CCM05787.1 - 0.032 13.4 0.1 0.053 12.6 0.1 1.2 1 0 0 1 1 1 0 ssDNA binding protein zf-C2H2 PF00096.21 CCM05788.1 - 5.6 7.5 9.6 1.3 9.5 0.4 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Peptidase_S10 PF00450.17 CCM05789.1 - 4.5e-102 342.3 0.0 5.7e-102 341.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCM05789.1 - 0.0003 20.7 0.0 0.0016 18.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family tRNA-synt_1b PF00579.20 CCM05790.1 - 9.9e-17 60.9 0.0 2.7e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Lipase_GDSL_2 PF13472.1 CCM05791.1 - 1.4e-06 28.6 0.0 3.9e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CCM05791.1 - 3.4e-05 23.7 0.0 0.0092 15.8 0.0 2.9 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Rad1 PF02144.11 CCM05792.1 - 4e-71 239.0 0.0 5.3e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PI-PLC-X PF00388.14 CCM05793.1 - 1.5e-06 27.6 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Lysine_decarbox PF03641.9 CCM05794.1 - 1e-29 102.9 0.0 1.5e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Hemerythrin PF01814.18 CCM05798.1 - 2.1e-10 40.8 9.7 2.1e-10 40.8 6.7 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain BTB PF00651.26 CCM05799.1 - 2.3e-06 27.5 0.0 9.8e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF2889 PF11136.3 CCM05799.1 - 0.095 12.9 0.6 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2889) Acyl-CoA_dh_1 PF00441.19 CCM05800.1 - 9.6e-06 25.7 0.1 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCM05800.1 - 0.002 17.5 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain p450 PF00067.17 CCM05801.1 - 1.4e-55 188.7 0.2 1.9e-55 188.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Kelch_4 PF13418.1 CCM05802.1 - 7.3e-19 67.2 1.9 1.6e-06 27.7 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CCM05802.1 - 3.4e-15 55.6 0.7 1.6e-05 24.7 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 CCM05802.1 - 1.1e-13 50.8 0.4 0.00014 21.9 0.0 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CCM05802.1 - 3.3e-13 49.1 1.8 0.011 15.8 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CCM05802.1 - 2e-12 46.3 0.6 0.0013 18.3 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 CCM05802.1 - 3.2e-12 45.7 0.0 0.012 15.1 0.0 4.1 4 0 0 4 4 4 3 Kelch motif RAG2 PF03089.9 CCM05802.1 - 0.00041 19.1 0.0 0.00075 18.3 0.0 1.4 1 0 0 1 1 1 1 Recombination activating protein 2 DUF2828 PF11443.3 CCM05803.1 - 2.5e-148 494.6 0.0 5.9e-148 493.3 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) Amidohydro_4 PF13147.1 CCM05803.1 - 0.095 12.7 0.3 9.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase CcoS PF03597.10 CCM05804.1 - 1.6 8.2 4.6 12 5.4 3.3 2.4 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Pro_CA PF00484.14 CCM05805.1 - 2.8e-37 128.0 0.3 3.4e-37 127.7 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Isochorismatase PF00857.15 CCM05805.1 - 0.0061 16.5 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family SNARE PF05739.14 CCM05805.1 - 0.064 12.9 0.9 0.12 12.0 0.2 1.8 2 0 0 2 2 2 0 SNARE domain PMI_typeI PF01238.16 CCM05807.1 - 1.6e-74 251.1 0.0 1.9e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 CCM05807.1 - 2e-05 23.9 0.4 0.0035 16.8 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Beta-lactamase PF00144.19 CCM05808.1 - 4.6e-20 71.9 0.1 5.9e-16 58.3 0.0 2.3 1 1 1 2 2 2 2 Beta-lactamase DUF2005 PF09407.5 CCM05808.1 - 0.026 13.2 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2005) p450 PF00067.17 CCM05809.1 - 2.4e-39 135.1 0.0 2.9e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DPBB_1 PF03330.13 CCM05810.1 - 0.003 17.5 0.2 0.033 14.1 0.0 2.3 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DPBB_1 PF03330.13 CCM05811.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Ycf9 PF01737.12 CCM05811.1 - 0.091 12.2 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 YCF9 BTB PF00651.26 CCM05812.1 - 0.00012 22.0 0.1 0.028 14.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Pkinase_Tyr PF07714.12 CCM05813.1 - 6.9e-52 176.0 0.0 1e-51 175.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM05813.1 - 5.9e-46 156.7 0.0 1.2e-45 155.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CCM05813.1 - 0.0015 17.6 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM05813.1 - 0.018 14.4 0.0 0.048 13.0 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 CCM05813.1 - 0.041 12.8 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Oscp1 PF10188.4 CCM05813.1 - 0.05 13.4 0.6 0.098 12.4 0.4 1.4 1 0 0 1 1 1 0 Organic solute transport protein 1 LRR_4 PF12799.2 CCM05815.1 - 0.0014 18.1 7.7 0.097 12.3 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM05815.1 - 0.82 9.4 15.8 2.2 8.0 0.0 5.3 6 1 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 CCM05815.1 - 7.8 6.9 11.6 6.2 7.2 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat DPBB_1 PF03330.13 CCM05816.1 - 0.012 15.6 0.4 0.13 12.3 0.0 2.4 2 1 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel 4HBT_2 PF13279.1 CCM05817.1 - 0.031 14.7 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily zf-MYND PF01753.13 CCM05818.1 - 3.8e-12 45.8 17.6 4.8e-12 45.5 10.1 2.2 2 0 0 2 2 2 1 MYND finger Ank_2 PF12796.2 CCM05818.1 - 1.6e-11 44.3 0.1 6.3e-11 42.4 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCM05818.1 - 2.4e-07 30.2 0.2 0.31 10.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCM05818.1 - 1.4e-05 25.2 0.3 0.00018 21.6 0.0 2.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCM05818.1 - 0.0016 18.9 0.0 0.035 14.6 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM05818.1 - 0.002 18.1 0.1 7.7 7.0 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat zf-ribbon_3 PF13248.1 CCM05818.1 - 0.054 12.7 2.6 0.13 11.4 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-HIT PF04438.11 CCM05818.1 - 1.6 8.4 12.0 0.091 12.4 4.6 1.8 2 0 0 2 2 2 0 HIT zinc finger Ank_2 PF12796.2 CCM05821.1 - 2.6e-37 127.0 1.5 6.1e-15 55.3 0.0 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CCM05821.1 - 1.4e-35 119.3 8.7 7.2e-09 35.0 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CCM05821.1 - 9.9e-31 105.0 9.0 3.4e-12 46.1 0.1 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCM05821.1 - 2.2e-28 98.0 3.6 1.3e-08 35.0 0.1 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCM05821.1 - 1.8e-23 80.2 2.2 0.00018 21.4 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat GPI-anchored PF10342.4 CCM05821.1 - 0.015 15.7 0.1 3.1 8.3 0.0 2.9 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Epimerase PF01370.16 CCM05823.1 - 4.4e-08 32.8 0.1 1e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CCM05823.1 - 2.3e-07 30.3 0.0 3.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 CCM05823.1 - 1.6e-06 27.3 0.1 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 CCM05823.1 - 2.9e-06 27.6 0.0 5.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCM05823.1 - 0.00011 22.2 0.1 0.00023 21.2 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 CCM05823.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 CCM05823.1 - 0.0018 17.2 0.1 0.0038 16.1 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 CCM05823.1 - 0.018 13.7 0.0 0.031 12.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CCM05823.1 - 0.023 15.1 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 CCM05823.1 - 0.043 12.7 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 CCM05823.1 - 0.048 13.3 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 CCM05823.1 - 0.086 12.7 1.4 0.27 11.1 0.2 2.2 2 1 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 CCM05823.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 CCM05824.1 - 2.3e-07 30.2 0.1 3.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CCM05824.1 - 2.7e-06 27.0 0.1 5.8e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM05824.1 - 8.4e-06 25.9 0.2 1.7e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CCM05824.1 - 1.7e-05 25.0 0.1 3.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CCM05824.1 - 2.1e-05 23.6 0.1 3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 CCM05824.1 - 6.6e-05 21.9 0.3 0.00013 20.9 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Shikimate_DH PF01488.15 CCM05824.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CCM05824.1 - 0.0086 16.4 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 CCM05824.1 - 0.01 14.5 0.1 0.022 13.4 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CCM05824.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 CCM05825.1 - 4.4e-06 26.1 0.0 7.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CCM05825.1 - 4.8e-06 26.1 0.0 0.0014 18.1 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCM05825.1 - 2.6e-05 24.4 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCM05825.1 - 7.1e-05 22.8 0.1 0.00011 22.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCM05825.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 CCM05825.1 - 0.0062 16.6 0.1 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CCM05825.1 - 0.015 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 CCM05825.1 - 0.044 12.4 0.1 0.083 11.5 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family LRR_8 PF13855.1 CCM05826.1 - 0.0011 18.6 0.0 3.4 7.4 0.0 4.0 4 1 0 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 CCM05826.1 - 0.19 12.0 2.5 15 6.3 0.0 4.6 6 0 0 6 6 6 0 Leucine rich repeat Zn_clus PF00172.13 CCM05828.1 - 0.009 15.9 13.3 0.014 15.3 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAM33 PF02330.11 CCM05829.1 - 1.5e-29 103.2 5.2 8e-27 94.3 3.6 2.2 1 1 0 1 1 1 1 Mitochondrial glycoprotein Lipocalin PF00061.18 CCM05829.1 - 0.1 12.5 0.1 17 5.3 0.0 2.3 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Med3 PF11593.3 CCM05830.1 - 0.014 14.7 0.5 0.02 14.1 0.3 1.2 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.17 CCM05831.1 - 7.8e-48 159.9 0.0 2.7e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM05831.1 - 1.1e-34 118.1 0.0 1e-11 44.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM05831.1 - 1.3e-18 66.5 0.0 9.5e-06 25.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCM05831.1 - 0.00051 19.7 0.0 0.016 14.9 0.0 3.1 3 1 0 3 3 3 1 Limkain b1 DUF3343 PF11823.3 CCM05831.1 - 0.11 11.7 0.0 0.35 10.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) MIP-T3 PF10243.4 CCM05831.1 - 0.96 7.8 40.9 1.3 7.3 28.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_transf_20 PF00982.16 CCM05832.1 - 8.1e-94 314.7 0.4 1.6e-75 254.4 0.0 2.3 2 1 1 3 3 3 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCM05832.1 - 2e-71 239.6 0.0 4.4e-71 238.5 0.0 1.5 2 0 0 2 2 2 1 Trehalose-phosphatase Lipase_GDSL_3 PF14606.1 CCM05832.1 - 0.16 11.7 0.0 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family His_Phos_2 PF00328.17 CCM05833.1 - 1.6e-43 149.3 0.0 2e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DNA_pol_A PF00476.15 CCM05834.1 - 1.7e-92 310.0 0.0 3.7e-92 308.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family A Cellulase PF00150.13 CCM05837.1 - 1.4e-14 53.9 0.0 2.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 CCM05837.1 - 0.00074 19.9 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like DUF1590 PF07629.6 CCM05837.1 - 1.7 8.3 5.1 1.3 8.7 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) F-box-like PF12937.2 CCM05838.1 - 8.3e-08 31.8 0.1 2.5e-07 30.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like Arrestin_N PF00339.24 CCM05839.1 - 1.7e-10 40.8 0.1 8.4e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCM05839.1 - 1.3e-05 25.3 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.5 CCM05839.1 - 0.18 10.8 0.2 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Rgp1 Arrestin_C PF02752.17 CCM05840.1 - 5.1e-08 33.1 0.1 0.00075 19.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCM05840.1 - 1.3e-06 28.3 0.0 5.4e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain adh_short PF00106.20 CCM05842.1 - 7.6e-10 38.9 0.0 1.2e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM05842.1 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 CCM05842.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 CCM05843.1 - 4.9e-11 42.8 0.0 6.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM05843.1 - 4.4e-06 26.4 0.0 7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Peptidase_C14 PF00656.17 CCM05844.1 - 1.6e-35 122.9 0.0 8e-35 120.7 0.0 1.9 1 1 0 1 1 1 1 Caspase domain adh_short PF00106.20 CCM05845.1 - 1.1e-08 35.1 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM05845.1 - 5.6e-06 26.1 0.0 8.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 CCM05845.1 - 0.088 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ycf34 PF10718.4 CCM05846.1 - 0.16 12.3 0.0 29 5.1 0.0 2.4 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 Ctr PF04145.10 CCM05847.1 - 8.5e-09 35.6 7.4 1.2e-08 35.1 4.8 1.3 1 1 0 1 1 1 1 Ctr copper transporter family DUF4310 PF14187.1 CCM05847.1 - 0.023 14.2 0.2 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) SMP PF04927.7 CCM05851.1 - 0.037 14.0 0.1 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Seed maturation protein Peptidase_C14 PF00656.17 CCM05852.1 - 5.1e-28 98.4 0.1 4.8e-27 95.2 0.0 2.0 1 1 0 1 1 1 1 Caspase domain adh_short PF00106.20 CCM05853.1 - 8.8e-10 38.7 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM05853.1 - 2.4e-05 24.0 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 CCM05854.1 - 1.4e-18 66.0 5.5 7.3e-08 32.0 0.3 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1961 PF09224.6 CCM05854.1 - 0.00066 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) AA_permease_2 PF13520.1 CCM05855.1 - 3e-59 200.6 42.9 2.2e-49 168.1 23.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 CCM05855.1 - 1.6e-08 33.3 29.1 1.6e-08 33.3 20.2 2.0 1 1 1 2 2 2 1 Amino acid permease HMG_box PF00505.14 CCM05857.1 - 3.5e-09 36.7 7.6 1.8e-08 34.5 5.3 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM05857.1 - 5.8e-09 36.1 3.2 1.3e-08 35.0 2.2 1.6 1 0 0 1 1 1 1 HMG-box domain Myc_target_1 PF15179.1 CCM05857.1 - 0.0092 15.5 0.7 0.0092 15.5 0.5 2.3 3 0 0 3 3 3 1 Myc target protein 1 Pkinase PF00069.20 CCM05860.1 - 2.5e-49 167.7 0.0 3.3e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05860.1 - 2.1e-27 95.8 0.0 2.8e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM05860.1 - 1.4e-07 30.8 0.0 2.7e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCM05860.1 - 0.024 14.3 0.1 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CCM05860.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WAPL PF07814.8 CCM05861.1 - 3.1e-14 52.4 0.6 2e-10 39.9 0.0 3.1 3 0 0 3 3 3 3 Wings apart-like protein regulation of heterochromatin BIR PF00653.16 CCM05862.1 - 4.2e-37 126.3 4.9 6.7e-19 68.0 1.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 CCM05862.1 - 2e-05 24.3 0.0 0.13 11.9 0.0 2.7 2 1 0 2 2 2 2 C3HC zinc finger-like zf-BED PF02892.10 CCM05862.1 - 0.0073 16.0 0.0 3.6 7.4 0.0 2.7 2 0 0 2 2 2 2 BED zinc finger Pkinase PF00069.20 CCM05863.1 - 2.7e-56 190.6 0.0 3.5e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05863.1 - 7.4e-28 97.3 0.0 9.4e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM05863.1 - 0.0013 17.8 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CCM05863.1 - 0.0023 16.8 0.2 0.0077 15.0 0.1 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CCM05863.1 - 0.0046 16.0 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CCM05863.1 - 0.042 13.1 0.1 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RRM_6 PF14259.1 CCM05864.1 - 9.2e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CCM05864.1 - 1.9e-05 24.2 3.3 3.1e-05 23.5 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 CCM05864.1 - 0.00056 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 CCM05864.1 - 0.001 18.6 4.0 0.0017 17.9 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCM05864.1 - 0.0014 18.2 4.1 0.0024 17.5 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCM05864.1 - 0.73 9.7 4.3 1.2 8.9 3.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CCM05864.1 - 3 7.9 5.3 4.9 7.2 3.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MRJP PF03022.11 CCM05865.1 - 2.5e-23 82.7 0.0 4.4e-23 81.9 0.0 1.4 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 CCM05865.1 - 7.3e-07 28.8 0.0 4.8e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 CCM05865.1 - 8.1e-05 22.5 2.6 0.023 14.6 0.0 3.5 3 1 1 4 4 4 2 Arylesterase DUF3429 PF11911.3 CCM05866.1 - 1.5e-35 122.2 13.8 2.3e-35 121.6 9.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) zf-Di19 PF05605.7 CCM05866.1 - 0.027 14.6 1.6 0.027 14.6 1.1 2.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF2378 PF09536.5 CCM05866.1 - 0.029 13.8 0.1 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) zf-C2H2_4 PF13894.1 CCM05866.1 - 5.1 7.6 6.1 1.9 9.0 0.9 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCM05867.1 - 0.023 14.9 2.5 0.63 10.4 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 CCM05867.1 - 0.032 14.5 0.2 0.032 14.5 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM05867.1 - 0.76 10.2 8.9 0.45 10.9 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger SIN1 PF05422.7 CCM05868.1 - 1.1e-42 146.2 0.0 3.6e-28 98.3 0.0 2.3 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 CCM05868.1 - 0.00045 20.0 0.0 0.002 18.0 0.0 2.1 3 0 0 3 3 3 1 GLUT4 regulating protein TUG Daxx PF03344.10 CCM05868.1 - 0.069 11.6 6.5 0.11 10.9 4.5 1.3 1 0 0 1 1 1 0 Daxx Family RBD PF02196.10 CCM05868.1 - 0.086 12.6 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Raf-like Ras-binding domain RA PF00788.18 CCM05868.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain TFIIA PF03153.8 CCM05868.1 - 0.76 9.6 5.3 1.4 8.7 3.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fe-S_biosyn PF01521.15 CCM05869.1 - 8e-13 48.3 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis bZIP_1 PF00170.16 CCM05871.1 - 0.00019 21.3 3.9 0.00028 20.7 2.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCM05871.1 - 0.014 15.1 3.3 0.022 14.6 2.3 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Fmp27_WPPW PF10359.4 CCM05872.1 - 0.017 13.5 0.1 0.023 13.1 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Lzipper-MIP1 PF14389.1 CCM05872.1 - 0.035 14.2 1.2 0.08 13.0 0.8 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 FlgD_ig PF13860.1 CCM05872.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 FlgD Ig-like domain TSC22 PF01166.13 CCM05872.1 - 2.9 7.9 4.5 2.2 8.2 1.2 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.13 CCM05872.1 - 3.7 7.3 5.5 17 5.2 0.8 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper YCII PF03795.9 CCM05874.1 - 0.00022 21.3 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain CTP_transf_2 PF01467.21 CCM05875.1 - 3.8e-27 95.2 0.0 4.9e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Amidohydro_1 PF01979.15 CCM05876.1 - 1.3e-18 67.8 0.1 1.5e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 CCM05876.1 - 1.7e-17 64.3 0.7 2.7e-09 37.4 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 CCM05876.1 - 2.1e-07 30.5 0.0 4.9e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 CCM05876.1 - 2.7e-05 23.8 0.0 7.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase DnaJ PF00226.26 CCM05877.1 - 0.031 14.0 1.3 0.41 10.4 0.0 2.7 2 0 0 2 2 2 0 DnaJ domain Spore_coat_CotO PF14153.1 CCM05877.1 - 0.037 13.4 10.2 0.18 11.2 0.2 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Laminin_I PF06008.9 CCM05878.1 - 0.024 13.9 8.1 0.44 9.8 0.5 2.1 1 1 1 2 2 2 0 Laminin Domain I Intein_splicing PF14890.1 CCM05878.1 - 0.029 13.2 0.2 0.045 12.6 0.1 1.3 1 0 0 1 1 1 0 Intein splicing domain DUF3452 PF11934.3 CCM05878.1 - 0.055 12.7 0.4 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Asp-B-Hydro_N PF05279.6 CCM05878.1 - 0.062 13.1 1.2 0.089 12.6 0.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Imm46 PF15585.1 CCM05878.1 - 0.091 12.8 0.3 0.35 10.9 0.0 2.0 1 1 0 2 2 2 0 Immunity protein 46 NYD-SP28 PF14772.1 CCM05878.1 - 0.12 12.5 5.7 0.81 9.8 1.4 2.3 1 1 1 2 2 2 0 Sperm tail TBPIP PF07106.8 CCM05878.1 - 0.17 11.4 9.1 0.29 10.6 2.1 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2497 PF10691.4 CCM05878.1 - 0.42 10.6 4.2 0.75 9.8 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2497) DUF4546 PF15079.1 CCM05878.1 - 0.57 9.3 3.3 1.1 8.3 2.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4546) DUF4047 PF13256.1 CCM05878.1 - 2.2 8.2 8.4 15 5.5 5.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) ABC_membrane PF00664.18 CCM05879.1 - 1.5e-45 155.7 5.9 2.1e-45 155.3 4.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCM05879.1 - 1.6e-30 106.1 0.0 4e-30 104.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCM05879.1 - 2.4e-06 26.9 0.2 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCM05879.1 - 0.002 18.1 0.1 0.15 11.9 0.0 2.4 1 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 CCM05879.1 - 0.008 16.0 0.1 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_17 PF13207.1 CCM05879.1 - 0.017 15.9 0.0 0.038 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CCM05879.1 - 0.045 13.2 0.1 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CCM05879.1 - 0.062 13.2 0.7 0.26 11.2 0.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.1 CCM05879.1 - 0.092 12.6 0.2 0.33 10.9 0.2 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 CCM05879.1 - 0.12 11.4 0.0 0.35 9.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin PGP_phosphatase PF09419.5 CCM05880.1 - 4.5e-46 156.2 0.0 6e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 CCM05880.1 - 0.048 13.3 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF3608 PF12257.3 CCM05881.1 - 8.8e-61 205.2 0.0 1.3e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 CCM05881.1 - 3.6e-18 65.0 0.0 7.3e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) BTB PF00651.26 CCM05882.1 - 9.7e-15 54.5 0.0 7.6e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain zf-H2C2 PF09337.5 CCM05882.1 - 0.03 13.7 0.2 0.065 12.6 0.2 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Fer4_11 PF13247.1 CCM05882.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pantoate_transf PF02548.10 CCM05883.1 - 3e-98 328.1 0.1 3.4e-98 327.9 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CCM05883.1 - 4.1e-08 32.7 0.5 2e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Kri1_C PF12936.2 CCM05885.1 - 1.7e-27 95.1 0.1 1.7e-27 95.1 0.1 5.2 7 0 0 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.7 CCM05885.1 - 8.8e-22 77.2 9.3 8.8e-22 77.2 6.5 6.9 7 1 0 7 7 7 3 KRI1-like family SAP PF02037.22 CCM05885.1 - 1.6 8.3 12.0 0.36 10.3 0.2 3.3 3 0 0 3 3 3 0 SAP domain DUF4646 PF15496.1 CCM05886.1 - 9.4e-37 125.8 0.0 1.6e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) PARP PF00644.15 CCM05888.1 - 2.1e-05 24.0 0.6 5e-05 22.8 0.3 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Cyclin PF08613.6 CCM05891.1 - 2.5e-05 24.7 0.5 4.5e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCM05891.1 - 5.9e-05 22.6 0.1 9.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain AF-4 PF05110.8 CCM05892.1 - 3.2 5.4 34.3 0.31 8.8 20.6 1.6 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Hid1 PF12722.2 CCM05892.1 - 3.3 5.2 9.8 4.6 4.8 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pex14_N PF04695.8 CCM05892.1 - 4.5 7.3 14.1 4.7 7.2 8.6 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec63 PF02889.11 CCM05893.1 - 2e-25 89.6 0.0 3.7e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 CCM05893.1 - 1.9e-15 56.3 0.0 4.8e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Na_H_Exchanger PF00999.16 CCM05894.1 - 3.8e-23 81.6 26.7 1.8e-11 43.2 2.2 4.2 3 2 0 3 3 3 3 Sodium/hydrogen exchanger family p450 PF00067.17 CCM05895.1 - 1.3e-56 192.0 0.0 4.4e-56 190.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 CCM05897.1 - 7.7e-09 34.7 0.0 1.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM05897.1 - 6.4e-05 22.7 7.4 6.4e-05 22.7 5.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gp_dh_C PF02800.15 CCM05898.1 - 5.8e-71 237.0 0.0 9.2e-71 236.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCM05898.1 - 1.4e-52 177.6 0.0 2.6e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 CCM05898.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Complex1_LYR PF05347.10 CCM05900.1 - 1.4e-10 40.7 0.7 2.1e-10 40.2 0.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCM05900.1 - 6.5e-08 32.6 0.3 1.1e-07 31.9 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like PP28 PF10252.4 CCM05901.1 - 5.6e-24 83.9 16.2 5.6e-24 83.9 11.2 2.7 3 1 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 SOBP PF15279.1 CCM05901.1 - 0.66 10.2 7.8 0.95 9.7 5.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PPR_2 PF13041.1 CCM05902.1 - 0.0024 17.7 0.0 0.053 13.4 0.0 3.0 3 0 0 3 3 3 1 PPR repeat family DUF2310 PF10071.4 CCM05902.1 - 0.03 13.3 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) RRM_1 PF00076.17 CCM05903.1 - 2.5e-14 52.6 0.0 3.4e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM05903.1 - 3.8e-10 39.6 0.0 5.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM05903.1 - 1.1e-06 28.3 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCM05903.1 - 0.0004 20.0 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 CCM05903.1 - 0.18 10.2 19.0 0.21 9.9 13.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RINGv PF12906.2 CCM05904.1 - 4.7e-06 26.5 8.7 8.8e-06 25.6 6.0 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CCM05904.1 - 0.0005 19.8 5.3 0.00087 19.0 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain PhnA_Zn_Ribbon PF08274.7 CCM05904.1 - 0.015 15.0 0.2 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-rbx1 PF12678.2 CCM05904.1 - 0.024 14.7 4.4 0.044 13.9 3.1 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 CCM05904.1 - 0.075 12.9 4.3 0.14 12.1 3.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 CCM05904.1 - 0.09 12.4 3.8 0.16 11.6 2.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCM05904.1 - 0.23 11.5 3.2 0.62 10.1 2.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.4 CCM05904.1 - 1.9 7.1 5.3 2.7 6.6 3.7 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor eIF2_C PF09173.6 CCM05905.1 - 4.3e-35 119.6 0.4 8.8e-35 118.6 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 CCM05905.1 - 3.7e-17 62.3 0.4 6.9e-17 61.4 0.3 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CCM05905.1 - 1.7e-11 44.0 0.4 1.7e-11 44.0 0.3 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Dak1_2 PF13684.1 CCM05905.1 - 0.081 11.8 0.4 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family DUF1778 PF08681.6 CCM05905.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) GTP_EFTU PF00009.22 CCM05906.1 - 1.7e-07 30.8 0.9 4.2e-07 29.5 0.6 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CCM05906.1 - 0.071 11.7 0.0 0.082 11.5 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.1 CCM05906.1 - 0.13 11.7 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 CCM05906.1 - 0.13 12.0 0.9 0.22 11.3 0.1 1.7 2 0 0 2 2 2 0 Dynamin family RasGEF PF00617.14 CCM05908.1 - 1.1e-20 74.1 0.0 2.7e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCM05908.1 - 1.2e-10 41.3 0.1 2.6e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif AAA_27 PF13514.1 CCM05908.1 - 0.16 9.6 0.2 0.23 9.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain Ldh_1_N PF00056.18 CCM05909.1 - 4.1e-45 153.0 0.3 6e-45 152.5 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCM05909.1 - 6.4e-39 133.4 0.0 9.5e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CCM05909.1 - 0.00027 19.7 0.0 0.00035 19.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 CCM05909.1 - 0.13 11.3 1.8 1.6 7.8 0.1 2.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GMC_oxred_N PF00732.14 CCM05910.1 - 2.9e-59 200.6 0.0 3.9e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM05910.1 - 1.5e-34 119.3 0.4 2.9e-34 118.4 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM05910.1 - 0.00026 19.9 1.2 0.0065 15.4 0.4 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM05910.1 - 0.0032 16.4 0.1 0.005 15.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCM05910.1 - 0.013 14.3 0.3 0.24 10.2 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain GMC_oxred_N PF00732.14 CCM05911.1 - 5e-57 193.2 0.0 7.6e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM05911.1 - 9e-35 120.0 0.1 1.6e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM05911.1 - 6.1e-05 22.0 1.2 0.017 14.0 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM05911.1 - 0.00012 21.1 0.3 0.00021 20.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCM05911.1 - 0.0023 16.8 0.6 0.095 11.5 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CCM05911.1 - 0.081 12.0 0.2 0.23 10.5 0.1 1.8 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 CCM05911.1 - 0.12 12.4 0.7 0.94 9.5 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CCM05911.1 - 0.18 10.3 0.1 0.26 9.8 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.14 CCM05912.1 - 6.4e-54 183.1 0.0 8.5e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM05912.1 - 5.4e-34 117.5 0.0 9.3e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM05912.1 - 0.0011 18.0 0.5 0.23 10.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM05912.1 - 0.0013 17.7 0.2 0.0021 17.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein RinB PF06116.7 CCM05912.1 - 0.024 14.2 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 Transcriptional activator RinB GMC_oxred_N PF00732.14 CCM05913.1 - 2e-65 220.8 0.0 2.6e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM05913.1 - 4.7e-34 117.7 0.1 8.4e-34 116.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCM05913.1 - 6.8e-05 21.9 0.7 0.0091 14.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM05913.1 - 0.00013 21.0 0.6 0.00023 20.1 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCM05913.1 - 0.0017 17.2 1.4 0.11 11.2 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CCM05913.1 - 0.0035 17.3 0.2 0.012 15.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCM05913.1 - 0.032 13.3 0.2 0.083 11.9 0.2 1.6 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 CCM05913.1 - 1.1 9.0 3.8 7.3 6.4 0.2 3.0 3 0 0 3 3 3 0 ThiF family RNA_pol_I_A49 PF06870.7 CCM05914.1 - 2.7e-97 325.7 0.2 3.1e-97 325.6 0.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SET PF00856.23 CCM05915.1 - 9.2e-19 68.3 0.6 1.1e-17 64.8 0.1 2.8 2 1 0 2 2 2 1 SET domain SRI PF08236.6 CCM05915.1 - 1.5e-17 63.2 9.5 3.4e-17 62.1 6.6 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Ish1 PF10281.4 CCM05916.1 - 1.2e-35 121.2 25.8 3.9e-07 30.0 1.3 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 CCM05916.1 - 0.041 13.4 0.0 73 3.0 0.0 4.6 5 0 0 5 5 5 0 HeH/LEM domain DUF883 PF05957.8 CCM05916.1 - 8.5 6.8 12.4 10 6.6 0.5 4.3 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.11 CCM05917.1 - 1.6e-18 66.5 42.2 7.9e-14 51.1 11.7 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1365 PF07103.6 CCM05918.1 - 3.4e-34 118.0 0.0 1.6e-33 115.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) Lipase_GDSL PF00657.17 CCM05919.1 - 7.2e-21 75.0 0.9 1.7e-15 57.5 0.2 3.1 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase DUF1989 PF09347.5 CCM05919.1 - 0.0033 16.8 0.1 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1989) Pkinase_Tyr PF07714.12 CCM05920.1 - 1.4e-40 139.0 0.0 1.9e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCM05920.1 - 2.8e-40 138.0 0.0 5.8e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CCM05920.1 - 1.8e-09 36.9 0.0 3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCM05920.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCM05920.1 - 0.065 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ASF1_hist_chap PF04729.8 CCM05921.1 - 1.9e-59 199.7 0.0 2.3e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone F-box PF00646.28 CCM05922.1 - 9.6e-05 21.9 0.2 0.00028 20.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCM05922.1 - 0.0023 17.5 0.8 0.0023 17.5 0.5 2.2 2 0 0 2 2 2 1 F-box-like DUF86 PF01934.12 CCM05922.1 - 0.13 11.9 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF86 GAS PF13851.1 CCM05923.1 - 0.028 13.6 7.0 0.65 9.1 0.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 CCM05923.1 - 0.029 12.6 8.2 0.038 12.3 5.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Hemerythrin PF01814.18 CCM05923.1 - 0.077 13.1 5.2 0.22 11.7 0.4 2.3 1 1 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF342 PF03961.8 CCM05923.1 - 0.13 10.6 5.9 0.051 12.0 1.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF1515 PF07439.6 CCM05923.1 - 0.15 11.8 1.6 0.26 11.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF1664 PF07889.7 CCM05923.1 - 0.38 10.5 2.2 1.2 8.9 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) GBP_C PF02841.9 CCM05923.1 - 0.41 9.7 4.6 1.1 8.3 0.1 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain FlaC_arch PF05377.6 CCM05923.1 - 0.5 10.2 4.4 28 4.6 0.0 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 CCM05923.1 - 0.52 10.2 12.6 0.67 9.8 1.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 CCM05923.1 - 0.72 8.8 12.7 0.13 11.2 2.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1640 PF07798.6 CCM05923.1 - 1.1 9.3 6.6 2.1 8.3 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) Striatin PF08232.7 CCM05923.1 - 1.2 9.4 9.6 0.34 11.2 3.9 2.0 1 1 1 2 2 2 0 Striatin family bZIP_1 PF00170.16 CCM05923.1 - 1.7 8.6 11.5 0.79 9.7 1.5 3.3 2 2 0 3 3 3 0 bZIP transcription factor Atg14 PF10186.4 CCM05923.1 - 2.7 6.8 12.8 0.88 8.4 2.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 CCM05923.1 - 2.8 7.6 11.8 0.58 9.9 1.3 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 CCM05923.1 - 3.9 7.0 17.6 4 6.9 1.3 3.8 2 2 2 4 4 4 0 Septum formation initiator Tropomyosin_1 PF12718.2 CCM05923.1 - 4.2 7.2 18.4 5.6 6.8 7.1 2.7 1 1 1 2 2 2 0 Tropomyosin like DUF1043 PF06295.7 CCM05923.1 - 5.7 6.5 6.5 1.3 8.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4201 PF13870.1 CCM05923.1 - 7 6.0 13.3 6.1 6.2 2.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) UCH PF00443.24 CCM05924.1 - 6.3e-41 140.2 0.0 9.6e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCM05924.1 - 9.1e-13 48.2 0.4 4.9e-12 45.9 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CCM05924.1 - 4.5e-05 22.7 0.0 0.00012 21.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Bap31 PF05529.7 CCM05925.1 - 4.7e-54 182.7 2.8 5.3e-54 182.5 1.9 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF2140 PF09911.4 CCM05925.1 - 0.027 13.6 0.4 0.027 13.6 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Cortexin PF11057.3 CCM05925.1 - 0.058 12.9 1.8 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 Cortexin of kidney DUF724 PF05266.9 CCM05925.1 - 0.51 9.9 5.9 0.69 9.4 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) OmpH PF03938.9 CCM05925.1 - 0.63 9.9 10.5 1 9.2 7.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.1 CCM05925.1 - 9 6.1 9.6 14 5.4 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BAG PF02179.11 CCM05926.1 - 2.2e-06 27.6 0.2 1.8e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 BAG domain DUF1150 PF06620.6 CCM05926.1 - 0.037 13.8 0.1 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) dCMP_cyt_deam_1 PF00383.17 CCM05927.1 - 6.2e-08 32.2 0.1 9.1e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PEMT PF04191.8 CCM05928.1 - 2.6e-46 156.0 12.7 5.4e-28 97.1 1.7 4.2 5 0 0 5 5 5 2 Phospholipid methyltransferase PP-binding PF00550.20 CCM05928.1 - 0.0095 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site PID PF00640.18 CCM05928.1 - 0.09 12.7 0.0 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Sas10 PF09368.5 CCM05929.1 - 1.1e-24 86.4 5.4 1.1e-24 86.4 3.7 2.4 3 0 0 3 3 3 1 Sas10 C-terminal domain DUF507 PF04368.8 CCM05929.1 - 0.081 12.5 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Fungal_trans PF04082.13 CCM05930.1 - 4.9e-10 38.7 0.3 7.8e-10 38.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM05930.1 - 5.9e-05 22.8 4.0 5.9e-05 22.8 2.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tom22 PF04281.8 CCM05931.1 - 2e-42 143.9 1.4 2.5e-42 143.6 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NAD_binding_10 PF13460.1 CCM05932.1 - 1.6e-18 67.3 0.0 2.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCM05932.1 - 1.8e-12 47.0 0.0 2.4e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 CCM05932.1 - 4.7e-11 42.1 0.0 1.7e-09 36.9 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 CCM05932.1 - 6.1e-11 42.1 0.3 1.8e-09 37.4 0.2 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM05932.1 - 3e-09 35.9 0.1 8.1e-09 34.5 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCM05932.1 - 1.5e-07 30.5 1.1 0.0021 17.0 0.8 3.4 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 CCM05932.1 - 0.009 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 CCM05932.1 - 0.067 12.0 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 CCM05932.1 - 0.092 12.6 0.3 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase DUF2462 PF09495.5 CCM05933.1 - 3.1e-17 63.0 14.2 3.7e-17 62.8 9.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) HTH_Tnp_Tc5 PF03221.11 CCM05934.1 - 4.5e-14 52.0 0.1 1.1e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.1 CCM05934.1 - 0.00062 19.3 0.1 0.0081 15.7 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.8 CCM05934.1 - 0.0027 17.0 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 CCM05934.1 - 0.0028 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.1 CCM05934.1 - 0.0077 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_31 PF13560.1 CCM05934.1 - 0.0078 16.3 0.1 3.1 8.0 0.0 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain Tap-RNA_bind PF09162.5 CCM05934.1 - 0.01 15.4 0.1 0.022 14.3 0.1 1.5 1 0 0 1 1 1 0 Tap, RNA-binding Sigma70_r4 PF04545.11 CCM05934.1 - 0.011 15.0 0.0 0.034 13.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 CCM05934.1 - 0.016 14.7 0.6 0.044 13.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1633 PF07794.6 CCM05934.1 - 0.028 12.3 2.9 0.042 11.8 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) MarR_2 PF12802.2 CCM05934.1 - 0.037 13.7 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_Tnp_4 PF13613.1 CCM05934.1 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease TrmB PF01978.14 CCM05934.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CAF1 PF04857.15 CCM05935.1 - 8.7e-67 225.2 0.0 1.3e-66 224.5 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease SH3_9 PF14604.1 CCM05936.1 - 3.7e-15 55.2 0.8 5.4e-09 35.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CCM05936.1 - 3.7e-13 48.7 1.2 1.8e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 CCM05936.1 - 4.7e-13 49.1 0.2 4.7e-13 49.1 0.1 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 CCM05936.1 - 1.5e-12 47.0 1.9 2.7e-12 46.2 1.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 CCM05936.1 - 6.2e-11 41.5 3.1 9e-06 24.9 0.4 2.7 2 1 0 2 2 2 2 SH3 domain SH3_3 PF08239.6 CCM05936.1 - 0.00053 20.1 0.6 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain FUSC PF04632.7 CCM05936.1 - 2 6.7 4.9 3.4 5.9 3.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DPBB_1 PF03330.13 CCM05937.1 - 0.0039 17.1 0.4 0.024 14.6 0.0 2.3 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CCM05937.1 - 0.014 15.1 0.1 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Barwin family GPI-anchored PF10342.4 CCM05938.1 - 1.8e-05 25.1 2.6 1.8e-05 25.1 1.8 3.4 2 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CCM05938.1 - 0.0051 16.3 0.2 0.012 15.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) zf-C3H1 PF10650.4 CCM05939.1 - 0.0092 15.4 0.9 0.017 14.6 0.7 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Bac_rhamnosid PF05592.6 CCM05941.1 - 2.9e-27 95.0 0.5 7.2e-26 90.4 1.7 2.1 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 CCM05941.1 - 0.019 13.6 4.5 0.031 13.0 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Trehalase PF01204.13 CCM05941.1 - 0.056 12.0 0.3 0.082 11.5 0.2 1.1 1 0 0 1 1 1 0 Trehalase Bac_rhamnosid PF05592.6 CCM05942.1 - 1.4e-28 99.4 4.2 6.1e-28 97.3 2.9 2.0 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 CCM05942.1 - 1.3e-05 24.1 4.8 2e-05 23.4 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 CCM05942.1 - 0.00053 18.7 0.4 0.00079 18.1 0.3 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 CCM05942.1 - 0.028 13.1 1.7 0.11 11.1 1.2 1.8 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase STE PF02200.11 CCM05944.1 - 1.5e-47 160.2 0.3 8e-47 157.9 0.0 2.1 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 CCM05944.1 - 2.5e-11 43.2 13.6 3e-05 24.0 2.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM05944.1 - 6.9e-09 35.4 16.7 0.00011 22.2 1.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCM05944.1 - 2.2e-06 27.6 3.8 2.2e-06 27.6 2.7 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCM05944.1 - 0.0042 17.1 5.6 0.33 11.1 0.7 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCM05944.1 - 0.014 15.2 0.9 0.014 15.2 0.6 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 CCM05944.1 - 0.6 9.9 3.8 10 6.0 0.7 2.5 2 0 0 2 2 2 0 BED zinc finger OTU PF02338.14 CCM05945.1 - 3.2e-14 53.5 0.0 6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CCM05945.1 - 0.00017 21.0 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain EAP30 PF04157.11 CCM05946.1 - 4.3e-29 101.2 0.0 6.7e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CCM05946.1 - 3.6e-21 74.7 0.0 6.5e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 CCM05946.1 - 1.4e-06 27.2 4.4 0.0071 15.4 0.6 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF742 PF05331.6 CCM05946.1 - 0.041 13.4 0.1 0.81 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF742) DZR PF12773.2 CCM05946.1 - 0.1 12.4 6.2 0.25 11.1 0.5 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 CCM05946.1 - 0.66 9.5 5.0 1.3 8.6 0.0 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.1 CCM05946.1 - 1.8 7.8 6.3 6.2 6.1 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Tnp_zf-ribbon_2 PF13842.1 CCM05946.1 - 3.8 8.0 5.4 17 5.9 0.7 2.5 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon PigN PF04987.9 CCM05948.1 - 1e-104 350.7 33.0 5.4e-92 308.7 16.0 2.1 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CCM05948.1 - 8.7e-13 48.3 1.0 2.8e-09 36.7 0.4 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CCM05948.1 - 0.00017 20.8 0.1 0.00028 20.1 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CCM05948.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PEMT PF04191.8 CCM05950.1 - 5.4e-28 97.1 5.4 6.1e-28 97.0 2.8 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1097 PF06496.6 CCM05950.1 - 0.1 12.3 0.3 0.1 12.3 0.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1097) ABC1 PF03109.11 CCM05951.1 - 4.5e-25 87.9 0.0 8.1e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family adh_short_C2 PF13561.1 CCM05953.1 - 3.5e-16 59.7 0.2 4.6e-16 59.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCM05953.1 - 5.7e-16 58.8 0.1 2.1e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM05953.1 - 3.3e-07 30.1 0.1 9e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 CCM05953.1 - 0.0057 15.8 0.0 0.0075 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Aldo_ket_red PF00248.16 CCM05954.1 - 1.6e-65 220.7 0.2 1.8e-65 220.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_fiss_reg PF05308.6 CCM05956.1 - 1.3 8.3 4.9 1.5 8.1 3.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator Aldo_ket_red PF00248.16 CCM05958.1 - 2.1e-56 190.8 0.0 1e-53 182.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TPR_12 PF13424.1 CCM05959.1 - 7.6e-14 51.4 0.0 1 9.3 0.0 8.8 5 3 5 10 10 10 3 Tetratricopeptide repeat TPR_10 PF13374.1 CCM05959.1 - 4.5e-05 23.2 10.8 12 6.0 0.1 9.4 11 0 0 11 11 11 0 Tetratricopeptide repeat bZIP_Maf PF03131.12 CCM05959.1 - 8.6e-05 22.7 0.0 1.7 8.9 0.0 4.6 5 0 0 5 5 5 2 bZIP Maf transcription factor Flp_Fap PF04964.9 CCM05959.1 - 0.00011 21.6 0.9 42 3.8 0.0 6.9 9 0 0 9 9 9 0 Flp/Fap pilin component KRAP_IP3R_bind PF14722.1 CCM05959.1 - 0.0013 18.3 0.6 32 4.0 0.0 6.2 7 2 2 9 9 9 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain TBCA PF02970.11 CCM05959.1 - 0.0016 18.5 1.0 25 5.0 0.0 5.7 7 0 0 7 7 7 0 Tubulin binding cofactor A FmdE PF02663.9 CCM05959.1 - 0.0017 18.2 0.0 3.7 7.4 0.0 3.9 5 0 0 5 5 5 1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF3247 PF11607.3 CCM05959.1 - 0.0056 16.8 1.3 11 6.2 0.0 4.5 4 1 1 5 5 5 1 Protein of unknown function (DUF3247) DUF2790 PF10976.3 CCM05959.1 - 0.034 13.9 0.0 9.4 6.1 0.0 4.1 3 2 2 5 5 5 0 Protein of unknown function (DUF2790) PMAIP1 PF15150.1 CCM05959.1 - 0.11 12.2 12.1 18 5.2 0.0 6.1 6 1 1 7 7 7 0 Phorbol-12-myristate-13-acetate-induced Fis1_TPR_N PF14852.1 CCM05959.1 - 0.11 11.8 0.0 36 3.7 0.0 3.5 4 0 0 4 4 4 0 Fis1 N-terminal tetratricopeptide repeat DUF3788 PF12663.2 CCM05959.1 - 1.5 8.5 3.0 39 3.9 0.0 4.7 7 0 0 7 7 7 0 Protein of unknown function (DUF3788) BLOC1_2 PF10046.4 CCM05959.1 - 2.6 8.2 5.6 56 3.9 0.0 5.4 7 0 0 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_12 PF13424.1 CCM05960.1 - 4.4e-10 39.3 0.0 7.3 6.6 0.0 9.4 7 3 4 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCM05960.1 - 3.9e-08 32.8 0.0 2 8.1 0.0 7.6 7 2 3 10 10 10 2 TPR repeat TPR_14 PF13428.1 CCM05960.1 - 9.5e-06 25.8 0.8 17 6.4 0.2 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCM05960.1 - 0.068 13.1 0.0 51 4.1 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 CCM05961.1 - 5.5e-20 72.1 0.0 9.1e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Caspase domain DUF3632 PF12311.3 CCM05962.1 - 7.4e-42 143.2 0.0 1.1e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) CHAT PF12770.2 CCM05963.1 - 1.1e-32 113.3 0.0 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 CCM05963.1 - 6.2e-12 44.9 0.0 11 5.7 0.0 11.6 9 4 7 16 16 16 2 TPR repeat TPR_8 PF13181.1 CCM05963.1 - 3.8e-11 41.9 0.0 24 4.9 0.0 12.0 14 0 0 14 14 14 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCM05963.1 - 9.1e-05 22.0 0.0 41 4.4 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat MCR_C PF04609.7 CCM05963.1 - 0.0053 15.6 0.0 13 4.4 0.0 4.8 5 1 1 6 6 6 1 Methyl-coenzyme M reductase operon protein C TSGP1 PF07771.6 CCM05963.1 - 1.2 9.0 2.5 2.3 8.1 1.7 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 Pea-VEAacid PF08111.6 CCM05963.1 - 2.6 8.3 6.5 0.7 10.1 0.0 3.5 3 0 0 3 3 3 0 Pea-VEAacid family Dus PF01207.12 CCM05964.1 - 3.4e-71 239.6 0.0 4.4e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.12 CCM05964.1 - 0.0027 17.3 0.0 0.029 13.9 0.0 2.0 1 1 1 2 2 2 1 SOR/SNZ family ThiG PF05690.9 CCM05964.1 - 0.0036 16.4 0.0 0.0056 15.7 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CCM05964.1 - 0.032 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TFIIA_gamma_C PF02751.9 CCM05966.1 - 4.8e-25 87.1 0.2 6.6e-25 86.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 CCM05966.1 - 9.1e-17 60.3 0.7 1.4e-16 59.7 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Scytalone_dh PF02982.9 CCM05966.1 - 0.073 12.6 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Scytalone dehydratase zf-C2H2_4 PF13894.1 CCM05970.1 - 0.15 12.4 13.7 0.24 11.8 4.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 CCM05970.1 - 0.24 11.5 4.8 0.52 10.4 2.8 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CCM05970.1 - 1.8 9.0 11.3 4.8 7.7 4.9 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type ADH_zinc_N PF00107.21 CCM05971.1 - 2.3e-31 108.0 0.0 4.1e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM05971.1 - 1.2e-14 55.3 0.5 3.1e-14 53.9 0.0 1.9 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCM05971.1 - 9.8e-08 31.7 0.1 4.2e-07 29.7 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.1 CCM05971.1 - 0.045 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 SIS domain R3H PF01424.17 CCM05973.1 - 8e-11 41.4 0.1 1.5e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-Di19 PF05605.7 CCM05974.1 - 0.00019 21.4 0.5 0.00058 19.9 0.1 2.0 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CCM05974.1 - 0.0064 16.7 0.2 0.023 15.0 0.1 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM05974.1 - 0.0092 16.2 0.2 0.0092 16.2 0.1 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CCM05975.1 - 0.055 13.8 5.9 0.055 13.8 4.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCM05975.1 - 0.065 13.5 0.2 0.065 13.5 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.7 CCM05975.1 - 0.36 10.9 8.0 0.48 10.5 4.5 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CCM05975.1 - 1.8 9.0 13.2 0.52 10.7 5.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM05976.1 - 0.029 14.7 6.7 0.1 12.9 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM05976.1 - 0.03 14.6 0.2 0.03 14.6 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Phage_integrase PF00589.17 CCM05978.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Phage integrase family Oxidored_FMN PF00724.15 CCM05979.1 - 3.5e-74 249.8 0.0 4.5e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.13 CCM05979.1 - 0.0068 15.2 1.1 0.024 13.5 0.3 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Dus PF01207.12 CCM05979.1 - 0.14 10.9 0.0 0.66 8.7 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 CCM05980.1 - 1.7e-73 247.5 0.0 2.1e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.13 CCM05980.1 - 0.011 14.5 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Dus PF01207.12 CCM05980.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Pkinase PF00069.20 CCM05981.1 - 1.2e-74 250.7 0.0 2.2e-74 249.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM05981.1 - 1.9e-45 154.9 0.0 3.3e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CCM05981.1 - 1.1e-30 105.3 2.6 2.5e-19 69.0 0.2 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CCM05981.1 - 8.5e-11 41.3 0.0 7.2e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCM05981.1 - 0.01 14.9 0.0 0.083 11.9 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4520 PF15016.1 CCM05981.1 - 0.03 13.8 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) APH PF01636.18 CCM05981.1 - 0.052 13.2 0.2 0.52 10.0 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Nop14 PF04147.7 CCM05983.1 - 1.9 6.2 15.2 3.6 5.4 10.5 1.3 1 0 0 1 1 1 0 Nop14-like family Aldedh PF00171.17 CCM05988.1 - 1.1e-170 567.9 0.3 1.2e-170 567.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CCM05988.1 - 0.057 12.6 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Cupin_2 PF07883.6 CCM05994.1 - 8.1e-07 28.4 0.0 5e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 CCM05994.1 - 3.9e-05 23.1 0.0 4.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Cupin GPI PF06560.6 CCM05994.1 - 0.0091 15.0 0.0 0.01 14.8 0.0 1.3 1 1 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Oxidored_FMN PF00724.15 CCM05995.1 - 1.5e-07 30.7 0.0 1.8e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TaqI_C PF12950.2 CCM05997.1 - 0.15 11.7 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain adh_short_C2 PF13561.1 CCM05998.1 - 1.6e-30 106.6 1.3 3e-30 105.7 0.9 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCM05998.1 - 5e-25 88.3 4.7 3.4e-24 85.6 3.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM05998.1 - 8.4e-12 45.1 0.7 2.1e-11 43.8 0.3 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CCM05998.1 - 1.9e-06 27.5 0.1 5e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CCM05998.1 - 7.3e-05 22.0 0.0 0.0001 21.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.10 CCM05998.1 - 0.00079 19.0 1.9 0.005 16.4 1.5 2.1 2 1 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.14 CCM05998.1 - 0.013 14.6 0.4 0.026 13.6 0.3 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HAD PF12710.2 CCM05998.1 - 0.019 15.1 0.2 0.2 11.8 0.1 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase adh_short PF00106.20 CCM05999.1 - 4.4e-19 69.0 0.1 6.2e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM05999.1 - 2.3e-08 33.9 0.1 3.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CCM06000.1 - 8.3e-20 71.3 0.0 1.1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM06000.1 - 1.8e-08 34.2 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCM06000.1 - 0.09 12.7 0.1 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 CCM06000.1 - 0.1 11.4 0.2 0.49 9.2 0.1 2.1 1 1 0 1 1 1 0 Male sterility protein adh_short PF00106.20 CCM06001.1 - 3e-16 59.7 0.0 4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM06001.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Peptidase_S10 PF00450.17 CCM06004.1 - 1.8e-111 373.2 0.0 2.4e-111 372.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCM06004.1 - 1.6e-06 28.2 0.2 3.3e-05 23.8 0.2 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family CcoS PF03597.10 CCM06006.1 - 0.076 12.4 2.4 0.21 11.0 1.7 1.8 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type adh_short PF00106.20 CCM06007.1 - 1.4e-19 70.6 0.3 1.9e-19 70.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM06007.1 - 8.5e-08 32.2 0.0 1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM06007.1 - 1.2e-06 28.3 0.0 1.6e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCM06007.1 - 0.031 14.2 0.1 0.069 13.1 0.1 1.5 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 CCM06007.1 - 0.034 13.5 0.1 0.047 13.1 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family BRI3BP PF14965.1 CCM06008.1 - 0.0013 18.1 0.7 0.0013 18.1 0.5 2.9 2 1 0 3 3 3 2 Negative regulator of p53/TP53 WD40 PF00400.27 CCM06010.1 - 9.9e-33 110.8 8.3 5.4e-12 45.0 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCM06010.1 - 1.2e-06 27.5 5.4 0.0054 15.5 0.1 3.1 1 1 2 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 CCM06010.1 - 0.0011 18.6 0.0 12 5.7 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 CCM06010.1 - 0.0026 17.2 6.4 0.0088 15.4 1.7 2.8 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 CCM06010.1 - 0.0041 15.3 1.7 0.47 8.5 0.0 2.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCM06010.1 - 0.0057 14.9 4.0 0.018 13.3 0.5 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain Mid2 PF04478.7 CCM06010.1 - 0.0077 15.6 0.0 0.78 9.1 0.0 2.6 1 1 2 3 3 3 2 Mid2 like cell wall stress sensor PQQ_2 PF13360.1 CCM06010.1 - 0.015 14.7 0.1 0.096 12.1 0.1 2.1 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.1 CCM06010.1 - 0.034 14.4 0.1 30 5.0 0.0 3.3 2 1 1 3 3 3 0 PQQ-like domain DUF4448 PF14610.1 CCM06011.1 - 0.024 14.1 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Sarcoglycan_2 PF05510.8 CCM06011.1 - 0.033 12.4 0.0 0.043 12.1 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Shisa PF13908.1 CCM06011.1 - 0.061 13.4 4.2 0.29 11.3 2.9 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator RabGAP-TBC PF00566.13 CCM06012.1 - 4.3e-09 36.1 0.5 5.9e-05 22.6 0.1 2.2 1 1 1 2 2 2 2 Rab-GTPase-TBC domain Pro-kuma_activ PF09286.6 CCM06013.1 - 4.5e-47 159.7 0.0 9.2e-47 158.6 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCM06013.1 - 6.3e-07 28.8 1.7 9.7e-07 28.2 1.2 1.3 1 0 0 1 1 1 1 Subtilase family Vps39_1 PF10366.4 CCM06014.1 - 4.8e-08 32.9 0.2 9e-06 25.6 0.0 2.9 1 1 1 2 2 2 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CCM06014.1 - 2.9e-07 30.6 0.0 8.4e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 CCM06014.1 - 4.4e-05 23.1 0.0 0.0011 18.5 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS CNH PF00780.17 CCM06015.1 - 2.8e-05 23.6 0.0 0.013 14.9 0.0 2.4 2 1 0 2 2 2 2 CNH domain CBS PF00571.23 CCM06016.1 - 3.5e-17 61.9 1.3 1.1e-05 25.1 0.0 4.6 4 1 1 5 5 5 4 CBS domain Perilipin PF03036.11 CCM06017.1 - 3.5e-15 55.7 7.6 8.2e-10 38.0 0.0 2.3 2 1 0 2 2 2 2 Perilipin family Apolipoprotein PF01442.13 CCM06017.1 - 6e-05 22.6 4.0 0.013 15.0 2.8 2.8 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF3437 PF11919.3 CCM06017.1 - 0.0062 16.2 0.6 0.017 14.7 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3437) Hormone_1 PF00103.15 CCM06017.1 - 0.032 13.5 2.0 0.072 12.4 1.4 1.6 1 0 0 1 1 1 0 Somatotropin hormone family DUF883 PF05957.8 CCM06017.1 - 0.035 14.4 7.2 1.8 8.9 0.3 3.3 4 1 0 4 4 3 0 Bacterial protein of unknown function (DUF883) DUF4088 PF13317.1 CCM06017.1 - 0.06 12.6 0.3 1.4 8.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4088) Phasin PF05597.6 CCM06017.1 - 0.14 11.8 1.9 10 5.8 0.0 3.0 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) COG2 PF06148.6 CCM06017.1 - 0.15 11.9 1.2 0.75 9.6 0.3 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.6 CCM06017.1 - 0.15 11.8 4.4 0.26 11.0 3.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 CCM06017.1 - 0.17 12.0 3.2 4.7 7.4 1.4 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 CCM06017.1 - 0.55 10.0 11.3 0.089 12.6 0.9 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ISG65-75 PF11727.3 CCM06017.1 - 0.57 9.1 3.5 2.4 7.1 0.9 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein TPR_MLP1_2 PF07926.7 CCM06017.1 - 3.7 7.2 7.2 62 3.3 4.9 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein COesterase PF00135.23 CCM06018.1 - 1.6e-56 192.1 0.0 4.5e-56 190.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM06018.1 - 2.7e-07 30.3 0.0 5.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold F-box-like PF12937.2 CCM06019.1 - 3.9e-07 29.7 0.5 1.1e-06 28.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like Polyketide_cyc2 PF10604.4 CCM06020.1 - 2.9e-08 33.9 0.2 0.00011 22.3 0.0 2.1 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport DUF791 PF05631.9 CCM06022.1 - 1.8e-56 191.3 4.5 3e-56 190.6 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 CCM06022.1 - 1.7e-16 59.9 18.2 1.7e-16 59.9 12.6 2.0 3 0 0 3 3 3 1 Major Facilitator Superfamily Sec23_trunk PF04811.10 CCM06023.1 - 1.7e-74 250.2 0.0 2.6e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCM06023.1 - 2.5e-35 120.0 0.3 5.6e-35 118.8 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCM06023.1 - 9.9e-29 99.7 0.3 2.1e-28 98.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCM06023.1 - 8.6e-17 60.4 6.6 1.7e-16 59.5 4.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCM06023.1 - 5.8e-13 48.3 0.0 1.9e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Oxidored_FMN PF00724.15 CCM06024.1 - 1.5e-71 241.1 0.0 1.9e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glycos_transf_1 PF00534.15 CCM06026.1 - 1.8e-20 73.0 0.0 4.8e-20 71.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCM06026.1 - 2.4e-08 34.2 0.0 5.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CCM06026.1 - 5.3e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 EI24 PF07264.6 CCM06027.1 - 1.9e-26 92.8 13.9 2.5e-26 92.4 9.6 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) tRNA_int_endo PF01974.12 CCM06028.1 - 9.3e-16 57.4 0.0 1.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF1682 PF07946.9 CCM06028.1 - 4.9 5.8 7.4 7 5.4 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Rhodanese PF00581.15 CCM06029.1 - 9.4e-13 48.5 0.0 2.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Pox_MCEL PF03291.11 CCM06030.1 - 5.7e-77 258.8 0.0 8.4e-76 254.9 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 CCM06030.1 - 2.9e-10 40.0 0.0 5.1e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM06030.1 - 4.9e-10 39.7 0.0 1.1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM06030.1 - 1.4e-09 38.4 0.0 2.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM06030.1 - 4.5e-09 36.6 0.0 8.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM06030.1 - 5.5e-09 35.7 0.0 8.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM06030.1 - 7.9e-08 32.5 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCM06030.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CCM06030.1 - 0.0032 16.4 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.9 CCM06030.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain HrpB4 PF09502.5 CCM06031.1 - 0.042 13.0 0.6 0.084 12.0 0.4 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) Phage_Treg PF04761.7 CCM06031.1 - 0.12 12.1 0.2 0.36 10.6 0.1 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator Dynamin_N PF00350.18 CCM06033.1 - 3.5e-27 95.2 0.0 6.5e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 CCM06033.1 - 4e-19 68.4 0.0 4.4e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 CCM06033.1 - 2e-06 27.5 1.7 2.3e-05 24.1 0.0 2.9 4 0 0 4 4 4 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCM06033.1 - 0.0018 18.1 0.0 0.025 14.5 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CCM06033.1 - 0.012 15.1 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CCM06033.1 - 0.025 14.0 0.0 1.1 8.6 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CCM06033.1 - 0.038 14.2 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Miro PF08477.8 CCM06033.1 - 0.048 14.1 0.0 0.3 11.5 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 CCM06033.1 - 0.076 12.9 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCM06033.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ceramidase_alk PF04734.8 CCM06034.1 - 2.1e-258 858.7 0.0 2.5e-258 858.4 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Sporozoite_P67 PF05642.6 CCM06035.1 - 0.0068 14.3 10.1 0.074 10.9 0.1 2.1 2 0 0 2 2 2 2 Sporozoite P67 surface antigen CobT PF06213.7 CCM06035.1 - 0.013 14.5 17.9 0.69 8.9 10.6 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT eIF-3c_N PF05470.7 CCM06035.1 - 0.048 11.7 2.4 0.087 10.8 1.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Afi1 PF07792.7 CCM06035.1 - 0.28 11.2 4.8 0.52 10.3 1.7 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Anoctamin PF04547.7 CCM06035.1 - 0.69 8.4 0.8 1.7 7.2 0.4 1.6 2 0 0 2 2 2 0 Calcium-activated chloride channel Radial_spoke PF04712.7 CCM06035.1 - 0.84 8.3 18.2 1.7 7.3 12.6 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein Daxx PF03344.10 CCM06035.1 - 1 7.7 19.4 0.03 12.8 8.6 1.7 2 0 0 2 2 2 0 Daxx Family Myc_N PF01056.13 CCM06035.1 - 2.5 7.1 18.3 0.06 12.4 7.8 1.8 2 0 0 2 2 2 0 Myc amino-terminal region FlxA PF14282.1 CCM06035.1 - 3.3 7.6 10.9 0.37 10.7 3.8 2.0 2 0 0 2 2 2 0 FlxA-like protein Adeno_terminal PF02459.10 CCM06035.1 - 6.1 4.8 8.4 8.6 4.3 5.8 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Vfa1 PF08432.5 CCM06035.1 - 7.3 6.5 11.1 4.4 7.2 3.7 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 His_Phos_2 PF00328.17 CCM06037.1 - 4.8e-05 22.8 0.0 0.00029 20.2 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) SRP72 PF08492.7 CCM06038.1 - 1.5e-08 34.8 0.3 1.5e-08 34.8 0.2 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 CCM06038.1 - 3.2e-07 30.3 0.6 8.6e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CCM06038.1 - 1.6e-05 25.1 0.4 0.0001 22.5 0.0 2.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCM06038.1 - 8.1e-05 23.1 0.3 0.093 13.4 0.0 2.7 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCM06038.1 - 0.0001 21.8 0.2 0.31 10.7 0.0 2.5 2 1 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 CCM06038.1 - 0.0013 19.2 0.1 0.37 11.5 0.0 3.3 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCM06038.1 - 0.0027 16.8 0.2 0.086 11.8 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCM06038.1 - 0.017 14.9 0.4 18 5.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCM06038.1 - 0.021 14.6 0.2 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pinin_SDK_memA PF04696.8 CCM06039.1 - 7e-11 41.8 23.1 1.8e-10 40.5 8.2 2.8 3 0 0 3 3 3 2 pinin/SDK/memA/ protein conserved region Vfa1 PF08432.5 CCM06039.1 - 0.4 10.6 18.8 0.19 11.7 5.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Snf7 PF03357.16 CCM06040.1 - 1.2e-35 122.4 8.5 1.2e-35 122.4 5.9 2.0 2 0 0 2 2 2 1 Snf7 DUF4186 PF13811.1 CCM06040.1 - 0.15 11.7 1.1 0.61 9.8 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4186) Atg14 PF10186.4 CCM06040.1 - 0.97 8.3 5.4 1.8 7.4 3.7 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Viral_P18 PF04521.8 CCM06040.1 - 3.6 7.0 6.2 3.5 7.0 0.7 2.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DRIM PF07539.7 CCM06042.1 - 2.3e-37 127.5 0.1 1.2e-36 125.1 0.0 2.5 2 0 0 2 2 2 1 Down-regulated in metastasis CTK3 PF12243.3 CCM06043.1 - 3.6e-29 101.1 0.0 6.5e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 AAA_12 PF13087.1 CCM06043.1 - 1.7e-21 76.5 0.3 7.8e-21 74.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCM06043.1 - 2.5e-20 73.0 0.7 2e-09 37.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 CCM06043.1 - 2.3e-17 63.1 0.6 6.5e-11 42.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain CTK3_C PF12350.3 CCM06043.1 - 6.7e-16 58.0 4.6 5e-15 55.2 3.2 2.5 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus AAA_19 PF13245.1 CCM06043.1 - 6.4e-09 35.4 0.0 9.6e-08 31.6 0.0 2.8 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 CCM06043.1 - 0.00069 19.6 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 CCM06043.1 - 0.0037 16.5 0.0 0.037 13.2 0.0 2.1 1 1 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.13 CCM06043.1 - 0.0042 16.6 0.5 1.2 8.5 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CCM06043.1 - 0.011 15.8 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCM06043.1 - 0.037 14.2 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 CCM06043.1 - 0.059 12.5 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 CCM06043.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GMC_oxred_N PF00732.14 CCM06044.1 - 1.5e-58 198.3 0.0 2e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM06044.1 - 4e-36 124.4 0.0 8.3e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCM06044.1 - 0.00017 20.5 0.7 0.18 10.6 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 CCM06044.1 - 0.0038 17.2 0.2 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CCM06044.1 - 0.013 14.4 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 CCM06044.1 - 0.045 12.8 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 CCM06044.1 - 0.074 12.9 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM06044.1 - 0.088 11.6 0.1 0.26 10.1 0.1 1.8 1 0 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 CCM06045.1 - 7.7e-63 212.3 0.0 1e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM06045.1 - 7.6e-34 117.0 0.0 1.3e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CCM06045.1 - 0.00079 19.4 1.5 0.0039 17.1 0.9 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCM06045.1 - 0.0052 15.7 0.7 0.037 12.9 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM06045.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCM06045.1 - 0.019 13.8 1.7 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 CCM06045.1 - 0.047 12.7 0.1 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 CCM06045.1 - 0.088 12.6 0.1 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RhoGAP PF00620.22 CCM06049.1 - 2.6e-16 59.5 0.0 5.3e-15 55.3 0.0 2.5 1 1 0 1 1 1 1 RhoGAP domain GPI-anchored PF10342.4 CCM06050.1 - 2.8e-08 34.1 0.1 3.5e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CCM06050.1 - 0.13 11.7 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Aminotran_5 PF00266.14 CCM06051.1 - 6.3e-39 133.7 0.0 8e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V GMC_oxred_N PF00732.14 CCM06052.1 - 3.5e-57 193.8 0.0 4.6e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCM06052.1 - 9.3e-35 120.0 0.0 1.5e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CCM06052.1 - 0.0012 18.7 0.7 0.0029 17.5 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCM06052.1 - 0.0021 16.9 0.9 1.5 7.5 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 CCM06052.1 - 0.044 12.8 0.1 0.25 10.3 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 CCM06052.1 - 0.055 13.3 0.0 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCM06052.1 - 0.074 11.9 0.3 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 CCM06052.1 - 0.096 11.5 2.0 0.22 10.3 0.3 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase PS_Dcarbxylase PF02666.10 CCM06055.1 - 1.1e-47 161.9 0.0 1.4e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase COesterase PF00135.23 CCM06056.1 - 9.8e-74 248.9 0.0 3.8e-71 240.4 0.0 2.3 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM06056.1 - 8.3e-10 38.5 0.4 3.6e-09 36.4 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM06056.1 - 4.4e-05 22.8 0.1 8.2e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCM06056.1 - 0.14 11.9 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pterin_bind PF00809.17 CCM06058.1 - 3.2e-50 170.4 0.0 8.4e-50 169.0 0.0 1.7 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 CCM06058.1 - 7.6e-33 112.9 0.0 1.3e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 CCM06058.1 - 1.3e-28 99.3 0.0 5.7e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase Fibrillarin PF01269.12 CCM06058.1 - 0.1 11.5 0.1 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin SSP160 PF06933.6 CCM06059.1 - 0.04 11.9 12.9 0.043 11.8 8.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UNC-79 PF14776.1 CCM06059.1 - 0.11 10.8 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Med3 PF11593.3 CCM06059.1 - 0.42 9.7 5.7 0.43 9.7 4.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RAP1 PF07218.6 CCM06059.1 - 3.7 5.5 7.7 4 5.4 5.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.4 CCM06059.1 - 8.6 5.7 10.8 10 5.5 7.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CFEM PF05730.6 CCM06060.1 - 2.2e-10 40.2 17.9 7.7e-10 38.4 12.4 2.0 1 0 0 1 1 1 1 CFEM domain DUF3956 PF13104.1 CCM06061.1 - 0.069 12.7 1.8 3.1 7.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3956) RHS_repeat PF05593.9 CCM06065.1 - 3.6e-14 52.4 59.2 4e-05 23.6 0.2 12.5 11 3 4 15 15 15 6 RHS Repeat VCBS PF13517.1 CCM06065.1 - 3.1e-05 24.2 6.1 0.00013 22.2 0.6 5.8 7 0 0 7 7 7 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RHS PF03527.9 CCM06065.1 - 0.0012 18.5 0.1 0.0047 16.6 0.1 2.1 1 0 0 1 1 1 1 RHS protein FG-GAP PF01839.18 CCM06065.1 - 0.0012 18.4 12.7 0.034 13.8 1.4 4.1 4 0 0 4 4 4 2 FG-GAP repeat RNA_pol_A_bac PF01000.21 CCM06067.1 - 2.2e-25 88.9 0.0 3.8e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCM06067.1 - 4.1e-13 48.2 0.0 5.6e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cyclophil_like PF04126.8 CCM06067.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin-like Cpn60_TCP1 PF00118.19 CCM06070.1 - 4.2e-117 391.7 7.3 4.9e-117 391.5 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transp_cyt_pur PF02133.10 CCM06071.1 - 4.5e-92 308.9 40.7 5.2e-92 308.6 28.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HEAT PF02985.17 CCM06072.1 - 7.8e-15 53.5 9.4 4.3e-07 29.4 0.0 7.3 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 CCM06072.1 - 2.2e-14 53.4 9.6 3.1e-06 27.5 0.0 8.3 7 1 2 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.1 CCM06072.1 - 2e-12 47.2 8.8 4.2e-05 23.7 0.0 6.0 5 2 2 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.2 CCM06072.1 - 1.5e-08 34.8 0.0 8.5e-07 29.2 0.0 3.5 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 CCM06072.1 - 2.2e-05 24.2 3.1 0.0017 18.0 0.0 4.5 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 CCM06072.1 - 0.0011 17.3 0.0 0.016 13.5 0.0 2.6 2 1 0 2 2 2 1 Adaptin N terminal region MMS19_C PF12460.3 CCM06072.1 - 0.0032 16.2 3.6 0.0093 14.7 0.0 3.2 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal DUF4042 PF13251.1 CCM06072.1 - 0.021 14.3 1.1 1.4 8.3 0.0 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4042) Cnd1 PF12717.2 CCM06072.1 - 0.027 14.3 0.0 20 4.9 0.0 3.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 FAD_binding_3 PF01494.14 CCM06073.1 - 4.9e-21 75.1 0.3 3.2e-20 72.5 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCM06073.1 - 5e-07 28.9 1.4 0.00016 20.7 1.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCM06073.1 - 4e-06 26.0 0.2 0.0072 15.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 CCM06073.1 - 4.4e-06 26.6 0.6 1.1e-05 25.3 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCM06073.1 - 1.5e-05 25.2 0.5 0.012 16.0 0.1 3.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCM06073.1 - 0.00027 19.6 1.6 0.035 12.7 0.9 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 CCM06073.1 - 0.0009 19.1 1.4 0.0023 17.8 0.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 CCM06073.1 - 0.0018 17.1 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.19 CCM06073.1 - 0.0024 16.7 4.8 0.0039 16.0 3.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CCM06073.1 - 0.007 15.4 0.2 0.013 14.6 0.2 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CCM06073.1 - 0.011 14.6 0.2 0.014 14.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 CCM06073.1 - 0.028 14.0 0.3 0.05 13.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 CCM06073.1 - 0.043 13.5 0.1 0.083 12.6 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain FAD_oxidored PF12831.2 CCM06073.1 - 0.065 12.3 0.3 0.091 11.8 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCM06073.1 - 0.08 12.9 0.2 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 CCM06073.1 - 0.18 11.6 1.3 0.38 10.5 0.9 1.5 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 CCM06073.1 - 0.23 9.8 1.2 0.97 7.8 1.1 1.7 2 0 0 2 2 2 0 HI0933-like protein PAH PF02671.16 CCM06074.1 - 4.2e-16 58.2 0.0 5.9e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Paired amphipathic helix repeat CN_hydrolase PF00795.17 CCM06076.1 - 4.3e-25 88.1 0.0 5.6e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_6 PF13964.1 CCM06076.1 - 0.094 12.9 0.0 0.69 10.1 0.0 2.4 3 0 0 3 3 3 0 Kelch motif DAGK_cat PF00781.19 CCM06077.1 - 5.3e-15 55.0 0.0 9.8e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ADK PF00406.17 CCM06078.1 - 5.2e-46 156.2 0.2 1.2e-45 155.1 0.1 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CCM06078.1 - 3.3e-07 30.6 0.0 6.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CCM06078.1 - 2.8e-06 26.8 1.7 3.2e-05 23.4 1.2 2.2 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 CCM06078.1 - 6.5e-06 26.0 0.0 7.9e-05 22.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCM06078.1 - 1e-05 26.3 0.0 2.9e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain F-box PF00646.28 CCM06078.1 - 8.2e-05 22.1 0.0 0.00028 20.4 0.0 1.9 1 0 0 1 1 1 1 F-box domain Zeta_toxin PF06414.7 CCM06078.1 - 0.073 12.1 0.2 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DnaJ PF00226.26 CCM06079.1 - 4.7e-22 77.4 1.6 7.8e-22 76.7 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCM06079.1 - 7e-19 67.5 2.4 7.5e-18 64.2 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCM06079.1 - 5.3e-15 55.2 20.1 1.1e-14 54.1 13.9 1.6 1 0 0 1 1 1 1 DnaJ central domain WD40 PF00400.27 CCM06079.1 - 0.0002 21.1 3.9 0.0025 17.6 0.1 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat HypA PF01155.14 CCM06079.1 - 0.9 9.2 11.4 1.2 8.8 2.0 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family COG4 PF08318.7 CCM06080.1 - 1.1e-53 182.1 0.0 1.8e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.8 CCM06080.1 - 0.016 13.7 0.0 0.043 12.3 0.0 1.6 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Pkip-1 PF06878.6 CCM06080.1 - 0.04 13.7 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Pkip-1 protein Ras PF00071.17 CCM06081.1 - 2.3e-52 176.6 0.0 2.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM06081.1 - 9.2e-17 61.6 0.0 1.2e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM06081.1 - 8.8e-08 31.5 0.0 1.9e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCM06081.1 - 0.021 13.9 0.0 0.049 12.7 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CCM06081.1 - 0.084 12.3 0.0 5.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CCM06081.1 - 0.1 12.7 0.0 1.3 9.1 0.0 2.2 1 1 0 2 2 2 0 AAA domain F-box-like PF12937.2 CCM06082.1 - 0.89 9.3 8.4 0.066 12.9 0.5 3.0 4 0 0 4 4 4 0 F-box-like F-box-like PF12937.2 CCM06085.1 - 0.0049 16.5 0.1 0.017 14.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like Plus-3 PF03126.13 CCM06085.1 - 0.11 12.4 0.1 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Plus-3 domain FAD_binding_3 PF01494.14 CCM06086.1 - 0.0035 16.4 0.0 0.016 14.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCM06086.1 - 0.019 13.8 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase PRP1_N PF06424.7 CCM06086.1 - 0.18 12.1 0.4 1.4 9.2 0.0 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal F-box-like PF12937.2 CCM06087.1 - 0.0012 18.5 0.1 0.0031 17.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like Mis14 PF08641.7 CCM06089.1 - 0.0011 19.0 3.0 0.0011 19.0 2.1 1.9 2 1 0 2 2 2 1 Kinetochore protein Mis14 like Transposase_22 PF02994.9 CCM06089.1 - 0.014 13.9 6.8 0.083 11.3 3.4 2.0 1 1 1 2 2 2 0 L1 transposable element Mitofilin PF09731.4 CCM06089.1 - 0.33 9.5 10.1 0.49 8.9 0.7 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Gar1 PF04410.9 CCM06090.1 - 1.2e-37 128.7 0.0 1.7e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.24 CCM06091.1 - 1.8e-64 215.8 0.0 2.2e-44 150.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCM06091.1 - 6.2e-10 39.9 0.0 0.0011 19.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCM06091.1 - 3.1e-08 33.8 2.2 0.0066 16.4 0.0 4.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.9 CCM06091.1 - 2.4e-07 30.5 0.0 0.02 14.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CCM06091.1 - 3e-07 30.7 0.0 0.012 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCM06091.1 - 8.6e-07 28.6 0.0 0.0037 16.9 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain RuvB_N PF05496.7 CCM06091.1 - 1.3e-06 27.6 0.0 0.0055 15.7 0.0 2.6 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CCM06091.1 - 8.9e-06 24.6 0.1 0.036 12.7 0.0 2.6 3 0 0 3 3 3 2 TIP49 C-terminus AAA_22 PF13401.1 CCM06091.1 - 9.9e-06 25.7 0.1 0.0053 16.8 0.0 3.8 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCM06091.1 - 1.8e-05 24.2 0.1 0.0011 18.4 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CCM06091.1 - 4.5e-05 23.3 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CCM06091.1 - 5.6e-05 22.6 0.1 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CCM06091.1 - 0.00015 21.8 0.0 0.067 13.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 CCM06091.1 - 0.00021 21.2 0.0 0.096 12.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 CCM06091.1 - 0.00022 20.4 0.1 0.036 13.2 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCM06091.1 - 0.00031 20.3 0.0 0.57 9.7 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCM06091.1 - 0.00056 19.4 0.0 1.5 8.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 CCM06091.1 - 0.00058 19.7 0.0 0.14 12.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain KaiC PF06745.8 CCM06091.1 - 0.00098 18.2 0.0 0.0046 16.1 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_2 PF07724.9 CCM06091.1 - 0.0016 18.4 0.0 0.026 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 CCM06091.1 - 0.0019 18.2 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 CCM06091.1 - 0.0058 16.2 0.4 0.078 12.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCM06091.1 - 0.0059 16.2 0.1 1.8 8.2 0.0 3.4 4 0 0 4 4 4 1 NACHT domain Zeta_toxin PF06414.7 CCM06091.1 - 0.0095 15.0 0.0 0.4 9.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 CCM06091.1 - 0.012 15.3 0.0 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 NTPase Parvo_NS1 PF01057.12 CCM06091.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 CCM06091.1 - 0.014 14.9 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CCM06091.1 - 0.02 13.7 0.0 1.9 7.2 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain PhoH PF02562.11 CCM06091.1 - 0.027 13.6 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Vps4_C PF09336.5 CCM06091.1 - 0.03 14.1 0.5 4.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain UPF0079 PF02367.12 CCM06091.1 - 0.066 12.8 0.0 0.87 9.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Molydop_binding PF01568.16 CCM06091.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_30 PF13604.1 CCM06091.1 - 0.084 12.4 0.0 2.5 7.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain SKI PF01202.17 CCM06091.1 - 0.097 12.5 0.0 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase DUF815 PF05673.8 CCM06091.1 - 0.12 11.3 0.0 0.73 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 CCM06091.1 - 0.24 10.3 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoD PF09423.5 CCM06092.1 - 1.2e-44 152.6 0.1 1.4e-36 126.0 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase DUF572 PF04502.8 CCM06093.1 - 5e-86 288.8 8.2 5.8e-86 288.6 5.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 CCM06093.1 - 0.017 14.7 1.2 0.36 10.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HrpA_pilin PF09589.5 CCM06093.1 - 0.033 14.6 0.1 0.06 13.7 0.1 1.5 1 0 0 1 1 1 0 HrpA pilus formation protein DUF866 PF05907.8 CCM06093.1 - 0.04 13.4 1.4 0.049 13.1 0.3 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) eIF3_subunit PF08597.5 CCM06093.1 - 0.82 9.1 14.9 0.95 8.9 9.9 1.4 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit OB_NTP_bind PF07717.11 CCM06094.1 - 4.3e-19 68.4 0.0 8.2e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCM06094.1 - 1.6e-18 66.6 0.0 3.1e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCM06094.1 - 8.3e-15 54.4 0.0 2e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1690 PF07956.6 CCM06094.1 - 5.9e-12 45.7 0.3 1.7e-11 44.2 0.2 1.8 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) DEAD PF00270.24 CCM06094.1 - 2.7e-07 30.2 0.0 4.9e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCM06094.1 - 9.6e-06 25.7 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCM06094.1 - 0.0029 16.5 0.0 0.0055 15.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 CCM06094.1 - 0.0031 17.1 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCM06094.1 - 0.032 14.1 0.1 0.51 10.2 0.1 2.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCM06094.1 - 0.048 12.7 0.6 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 CCM06094.1 - 0.16 10.8 0.0 0.31 9.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Herpes_gE PF02480.11 CCM06095.1 - 0.0037 15.6 0.1 0.0049 15.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4381 PF14316.1 CCM06095.1 - 0.056 13.5 0.3 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Myb_Cef PF11831.3 CCM06096.1 - 6.8e-56 189.0 2.3 6.8e-56 189.0 1.6 3.6 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 CCM06096.1 - 1.8e-20 72.6 5.7 8.3e-11 41.7 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCM06096.1 - 1.7e-17 63.2 7.9 3.1e-12 46.4 2.3 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2340 PF10209.4 CCM06097.1 - 2e-44 150.6 0.4 2.3e-44 150.4 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Ubiquitin_2 PF14560.1 CCM06097.1 - 0.074 13.3 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Glyco_hydro_3 PF00933.16 CCM06098.1 - 6.2e-68 228.9 0.0 9.1e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCM06098.1 - 4e-61 206.4 0.0 1.4e-60 204.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCM06098.1 - 8.5e-22 76.8 0.4 1.7e-21 75.9 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 CCM06098.1 - 8e-11 41.7 0.0 1.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.4 CCM06098.1 - 0.2 10.2 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Myosin_head PF00063.16 CCM06099.1 - 4.1e-239 795.2 0.0 6.2e-239 794.6 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 CCM06099.1 - 8.6e-34 115.5 1.5 8.6e-34 115.5 1.0 2.4 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 CCM06099.1 - 7.8e-15 53.0 31.8 0.0026 17.2 0.5 7.2 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.1 CCM06099.1 - 0.016 15.3 4.2 0.062 13.4 0.0 3.6 3 1 0 3 3 3 0 AAA domain DUF4559 PF15112.1 CCM06099.1 - 1.7 7.6 14.1 3.3 6.7 9.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) SlyX PF04102.7 CCM06099.1 - 7.6 6.9 18.5 0.94 9.8 1.4 3.5 2 1 1 3 3 3 0 SlyX Fe-ADH PF00465.14 CCM06102.1 - 1.8e-54 184.8 1.7 2.4e-54 184.4 1.2 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CCM06102.1 - 3.7e-35 121.4 0.1 4.6e-35 121.1 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 CCM06102.1 - 1.1e-05 24.5 0.5 0.00023 20.1 0.3 2.4 1 1 0 1 1 1 1 3-dehydroquinate synthase S-methyl_trans PF02574.11 CCM06103.1 - 1.6e-34 119.6 0.0 1.6e-18 67.0 0.0 2.7 1 1 1 2 2 2 2 Homocysteine S-methyltransferase Glucosamine_iso PF01182.15 CCM06104.1 - 1.5e-22 80.3 0.0 2.6e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase LRR_4 PF12799.2 CCM06105.1 - 2.4e-54 180.1 49.1 3.8e-09 35.9 1.3 13.2 8 2 5 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCM06105.1 - 1.4e-44 149.6 54.6 9.8e-16 57.2 3.2 9.6 4 3 9 13 13 13 10 Leucine rich repeat PP2C PF00481.16 CCM06105.1 - 2.1e-41 141.9 0.0 3.5e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 CCM06105.1 - 1e-29 97.9 52.6 0.0064 16.3 0.1 18.8 19 0 0 19 19 19 11 Leucine Rich Repeat Guanylate_cyc PF00211.15 CCM06105.1 - 2.2e-23 82.5 0.0 3.7e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_7 PF13504.1 CCM06105.1 - 7.9e-13 46.3 55.8 3.5 8.2 0.1 18.7 20 0 0 20 20 20 5 Leucine rich repeat RA PF00788.18 CCM06105.1 - 7.1e-07 29.6 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.6 CCM06105.1 - 0.00052 19.2 0.2 0.0016 17.7 0.1 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.1 CCM06105.1 - 0.064 12.9 0.2 5.4 6.7 0.0 2.9 2 1 0 2 2 2 0 Leucine rich repeats (6 copies) LRR_6 PF13516.1 CCM06105.1 - 0.088 12.9 55.7 9.8 6.6 0.0 16.3 17 2 1 18 18 18 0 Leucine Rich repeat Acyltransferase PF01553.16 CCM06106.1 - 1.6e-18 66.3 0.0 2.9e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SPC22 PF04573.7 CCM06107.1 - 9.1e-37 125.9 0.1 5.8e-30 103.8 0.0 2.0 2 0 0 2 2 2 2 Signal peptidase subunit Zn_clus PF00172.13 CCM06108.1 - 0.00019 21.2 9.3 0.0004 20.2 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mg_trans_NIPA PF05653.9 CCM06109.1 - 3.9e-83 278.8 28.8 5.4e-83 278.4 20.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CCM06109.1 - 3.7e-07 30.2 7.7 3.7e-07 30.2 5.4 3.8 3 1 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 CCM06109.1 - 9.1e-05 22.6 13.8 9.1e-05 22.6 9.6 4.0 1 1 2 3 3 3 1 Multidrug resistance efflux transporter Neurensin PF14927.1 CCM06109.1 - 2.6 7.4 5.6 7.7 5.8 0.0 2.9 2 0 0 2 2 2 0 Neurensin AAA_16 PF13191.1 CCM06110.1 - 0.013 15.5 0.1 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 CCM06110.1 - 0.022 13.6 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.15 CCM06110.1 - 0.038 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.7 CCM06110.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Torsin PF06309.6 CCM06110.1 - 0.081 12.8 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Torsin Abhydrolase_6 PF12697.2 CCM06111.1 - 0.0041 17.0 0.5 0.0072 16.2 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.7 CCM06111.1 - 0.012 15.3 0.1 0.019 14.6 0.1 1.4 1 1 0 1 1 1 0 NACHT domain WD40 PF00400.27 CCM06113.1 - 1.6e-46 154.5 17.3 1.5e-13 50.0 0.3 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Gmad1 PF10647.4 CCM06113.1 - 5.5e-07 29.2 9.8 3e-05 23.5 1.7 2.6 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 CCM06113.1 - 5.4e-06 24.8 5.1 0.047 11.8 0.0 3.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCM06113.1 - 0.00043 19.8 5.2 0.011 15.2 0.2 2.0 1 1 1 2 2 2 2 PQQ-like domain PD40 PF07676.7 CCM06113.1 - 0.0027 17.3 1.6 13 5.5 0.0 4.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 CCM06113.1 - 0.0036 17.5 1.1 5.1 7.4 0.0 3.8 3 1 1 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.6 CCM06113.1 - 0.0088 14.8 6.9 0.98 8.0 0.1 3.6 1 1 2 4 4 4 2 Nup133 N terminal like Peptidase_S9_N PF02897.10 CCM06113.1 - 0.08 11.5 0.3 2.5 6.5 0.0 2.7 2 2 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Ribosomal_TL5_C PF14693.1 CCM06113.1 - 0.086 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain DUF2388 PF09498.5 CCM06113.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) NYD-SP28_assoc PF14775.1 CCM06113.1 - 0.26 11.0 2.9 83 2.9 0.0 4.4 5 0 0 5 5 5 0 Sperm tail C-terminal domain WD40 PF00400.27 CCM06114.1 - 1.2e-165 532.1 55.0 6.4e-13 48.0 0.1 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCM06114.1 - 3.9e-17 62.1 31.1 0.21 10.2 0.1 12.3 1 1 9 10 10 10 9 Nup133 N terminal like Nup160 PF11715.3 CCM06114.1 - 1.9e-08 32.9 22.7 0.19 9.8 0.0 9.8 1 1 8 10 10 10 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCM06114.1 - 1e-07 31.7 20.6 0.32 10.4 4.2 6.0 1 1 3 4 4 4 4 PQQ-like domain NACHT PF05729.7 CCM06114.1 - 2.1e-07 30.7 0.0 2.9e-06 27.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain PQQ_3 PF13570.1 CCM06114.1 - 4.4e-06 26.7 14.0 15 5.9 0.0 9.9 9 4 3 12 12 12 0 PQQ-like domain PD40 PF07676.7 CCM06114.1 - 2.7e-05 23.6 11.9 27 4.5 0.0 9.2 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 CCM06114.1 - 0.00014 20.2 0.0 1.2 7.2 0.0 5.0 3 1 2 5 5 5 1 Protein of unknown function (DUF3312) AAA_16 PF13191.1 CCM06114.1 - 0.00039 20.4 0.1 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ASCH PF04266.9 CCM06114.1 - 0.007 16.7 1.9 59 4.1 0.0 5.7 5 0 0 5 5 5 0 ASCH domain NB-ARC PF00931.17 CCM06114.1 - 0.092 11.5 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ketoacyl-synt PF00109.21 CCM06115.1 - 3.5e-55 187.2 1.1 5.5e-55 186.5 0.2 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CCM06115.1 - 1.4e-30 106.7 0.0 2.8e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 CCM06115.1 - 3.5e-28 98.5 1.0 1.2e-15 57.6 0.1 2.7 1 1 1 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.17 CCM06115.1 - 1.3e-27 95.9 0.2 3.3e-27 94.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 CCM06115.1 - 7e-23 81.3 5.8 2.2e-21 76.4 1.9 3.2 2 1 0 2 2 1 1 short chain dehydrogenase PS-DH PF14765.1 CCM06115.1 - 5.3e-22 78.3 0.0 1.2e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 CCM06115.1 - 1.8e-18 67.6 0.0 3.5e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Methyltransf_12 PF08242.7 CCM06115.1 - 9.8e-13 48.4 0.0 2.7e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM06115.1 - 4.5e-11 42.7 0.0 9.9e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 CCM06115.1 - 1.2e-08 35.1 0.0 5.5e-08 32.9 0.0 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 CCM06115.1 - 5.2e-08 33.2 0.0 5.9e-07 29.8 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM06115.1 - 9.9e-08 31.7 0.0 3.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ACP_syn_III PF08545.5 CCM06115.1 - 3e-05 23.5 1.7 0.00019 20.9 1.2 2.5 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_18 PF12847.2 CCM06115.1 - 4.4e-05 24.0 0.0 0.00015 22.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 CCM06115.1 - 0.0005 19.1 0.0 0.0011 17.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.21 CCM06115.1 - 0.0019 17.7 0.0 0.0087 15.6 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 CCM06115.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CCM06115.1 - 0.036 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_I_A49 PF06870.7 CCM06115.1 - 0.71 8.3 0.0 1.1 7.7 0.0 1.2 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor NACHT PF05729.7 CCM06117.1 - 9.2e-06 25.4 0.1 8.2e-05 22.3 0.1 2.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CCM06117.1 - 6.1e-05 23.0 0.1 0.0004 20.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 CCM06117.1 - 0.00027 19.8 0.0 0.00052 18.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 CCM06117.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 CCM06118.1 - 3e-64 216.6 0.0 5.3e-64 215.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06118.1 - 4.9e-36 124.1 0.0 1.4e-22 80.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCM06118.1 - 1.4e-05 24.1 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCM06118.1 - 8.6e-05 22.3 4.9 0.012 15.3 0.1 3.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family LEA_6 PF10714.4 CCM06118.1 - 0.054 13.3 1.0 0.1 12.3 0.2 1.9 1 1 0 1 1 1 0 Late embryogenesis abundant protein 18 DASH_Dad4 PF08650.5 CCM06119.1 - 1.4e-19 69.7 1.1 1.6e-19 69.5 0.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 CCM06119.1 - 0.018 14.7 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 Pneumovirus_M2 PF06436.6 CCM06119.1 - 0.039 13.1 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) NDUF_B12 PF08122.7 CCM06120.1 - 0.098 12.4 2.2 19 5.1 0.0 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Lge1 PF11488.3 CCM06120.1 - 0.21 11.8 1.7 4.9 7.4 0.1 2.8 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 APH PF01636.18 CCM06121.1 - 0.006 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CCM06121.1 - 0.032 13.3 0.0 0.15 11.2 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 CCM06121.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 CCM06122.1 - 0.017 14.3 0.0 0.22 10.6 0.0 2.2 1 1 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 CCM06122.1 - 0.046 13.0 0.2 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family CoA_transf_3 PF02515.12 CCM06125.1 - 1e-63 214.0 0.0 1.5e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Transket_pyr PF02779.19 CCM06126.1 - 1.5e-65 220.0 0.0 2.4e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CCM06126.1 - 8.8e-57 192.0 0.0 1.2e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF663 PF04950.7 CCM06127.1 - 2.2e-88 296.1 1.5 3.3e-88 295.4 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCM06127.1 - 2.3e-28 97.5 0.0 6.8e-28 96.0 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CCM06127.1 - 2.3e-08 33.6 0.1 5.1e-05 22.7 0.0 3.0 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 CCM06127.1 - 1.9e-06 28.7 1.8 0.00028 21.6 0.0 3.7 2 2 1 3 3 3 1 AAA domain AAA_22 PF13401.1 CCM06127.1 - 5.9e-05 23.2 0.7 0.00031 20.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCM06127.1 - 7e-05 22.5 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 CCM06127.1 - 7.7e-05 22.4 0.2 0.00024 20.8 0.1 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CCM06127.1 - 0.00011 21.7 0.1 0.00032 20.2 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 CCM06127.1 - 0.00012 22.1 0.3 0.00059 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 CCM06127.1 - 0.00045 20.7 0.1 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein NB-ARC PF00931.17 CCM06127.1 - 0.00092 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.1 CCM06127.1 - 0.0014 19.0 1.5 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CCM06127.1 - 0.0018 18.5 0.0 0.0018 18.5 0.0 2.7 3 0 0 3 3 2 1 ABC transporter AAA PF00004.24 CCM06127.1 - 0.0019 18.4 0.1 0.006 16.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCM06127.1 - 0.0024 17.7 0.0 0.0069 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCM06127.1 - 0.0052 16.6 1.5 0.0076 16.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CCM06127.1 - 0.0056 16.9 6.2 0.0068 16.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 CCM06127.1 - 0.0061 15.7 0.1 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CCM06127.1 - 0.0066 16.3 0.5 0.031 14.2 0.2 2.3 2 1 0 2 2 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 CCM06127.1 - 0.01 15.5 0.1 0.028 14.1 0.1 1.8 1 0 0 1 1 1 0 NTPase cobW PF02492.14 CCM06127.1 - 0.016 14.6 0.1 0.041 13.3 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 CCM06127.1 - 0.019 14.3 0.0 0.064 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 CCM06127.1 - 0.019 15.1 0.0 0.074 13.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CCM06127.1 - 0.024 14.2 1.5 0.027 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 CCM06127.1 - 0.051 13.2 0.0 0.051 13.2 0.0 2.2 2 0 0 2 2 1 0 Archaeal ATPase AAA_19 PF13245.1 CCM06127.1 - 0.087 12.5 0.3 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain ATP_bind_1 PF03029.12 CCM06127.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 CCM06127.1 - 4.9 6.5 7.0 0.14 11.5 0.1 1.9 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Cep57_MT_bd PF06657.8 CCM06128.1 - 3e-14 52.7 17.5 3.6e-11 42.8 0.1 4.3 4 1 0 4 4 4 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 CCM06128.1 - 6.4e-12 45.2 6.5 6.4e-12 45.2 4.5 3.2 3 1 1 4 4 4 1 Centrosome localisation domain of PPC89 IFT57 PF10498.4 CCM06128.1 - 0.024 13.3 8.1 0.2 10.3 0.8 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4407 PF14362.1 CCM06128.1 - 2.9 6.7 11.2 1.2 8.0 0.7 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) IncA PF04156.9 CCM06128.1 - 3 7.3 25.8 0.056 13.0 6.9 2.4 1 1 1 2 2 2 0 IncA protein Nipped-B_C PF12830.2 CCM06130.1 - 3e-53 180.2 0.2 7.3e-53 178.9 0.1 1.7 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus HA2 PF04408.18 CCM06130.1 - 9.4e-22 76.9 0.5 4.7e-21 74.7 0.0 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) Cohesin_HEAT PF12765.2 CCM06130.1 - 2.5e-13 49.6 0.6 2.6e-12 46.4 0.3 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Helicase_C PF00271.26 CCM06130.1 - 2.2e-12 46.6 0.0 5.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CCM06130.1 - 4.1e-08 33.0 0.0 1.4e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CCM06130.1 - 5.3e-06 26.0 0.1 1.3e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCM06130.1 - 7.1e-06 26.2 0.0 5.1e-05 23.4 0.0 2.6 1 0 0 1 1 1 1 AAA domain Adaptin_N PF01602.15 CCM06130.1 - 0.0019 16.5 0.4 0.0049 15.2 0.3 1.6 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 CCM06130.1 - 0.033 14.2 0.3 2.4 8.4 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat AAA_29 PF13555.1 CCM06130.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 CCM06130.1 - 0.062 12.4 0.1 0.18 10.8 0.1 1.7 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CCM06130.1 - 0.19 12.0 0.7 0.56 10.4 0.5 1.8 1 0 0 1 1 1 0 AAA domain KR PF08659.5 CCM06132.1 - 2.8e-27 95.5 1.8 1.8e-23 83.1 0.0 2.9 3 0 0 3 3 3 2 KR domain adh_short PF00106.20 CCM06132.1 - 6.1e-25 88.0 3.3 1.3e-19 70.6 0.0 3.3 3 0 0 3 3 3 2 short chain dehydrogenase NAD_binding_4 PF07993.7 CCM06132.1 - 5.4e-22 77.9 0.1 2.2e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein PP-binding PF00550.20 CCM06132.1 - 3.9e-06 27.0 3.6 1.1e-05 25.5 0.1 2.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Nnf1 PF03980.9 CCM06133.1 - 6.7e-12 45.3 0.7 6.7e-12 45.3 0.5 1.6 2 0 0 2 2 2 1 Nnf1 TMF_TATA_bd PF12325.3 CCM06133.1 - 0.0054 16.4 1.4 0.0054 16.4 1.0 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 CCM06133.1 - 0.051 13.8 2.2 0.051 13.8 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 CCM06133.1 - 0.1 12.5 0.5 0.1 12.5 0.4 2.1 2 1 0 2 2 2 0 bZIP transcription factor CCDC155 PF14662.1 CCM06133.1 - 0.11 12.0 6.8 0.34 10.4 4.8 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 CASP_C PF08172.7 CCM06133.1 - 0.16 10.9 3.4 0.24 10.3 2.3 1.4 1 1 0 1 1 1 0 CASP C terminal THOC7 PF05615.8 CCM06133.1 - 0.23 11.7 3.5 0.94 9.7 0.3 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 ORC3_N PF07034.6 CCM06133.1 - 0.3 10.0 2.6 0.16 10.9 0.3 1.6 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus DivIC PF04977.10 CCM06133.1 - 0.56 9.7 2.5 0.96 8.9 0.5 2.0 2 0 0 2 2 2 0 Septum formation initiator Herpes_BLRF2 PF05812.7 CCM06133.1 - 0.78 9.5 4.5 0.77 9.5 1.0 2.0 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein APG6 PF04111.7 CCM06133.1 - 2.1 7.3 8.0 10 5.0 5.1 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 FliD_C PF07195.7 CCM06134.1 - 0.081 12.2 1.7 0.17 11.1 1.2 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus NTR2 PF15458.1 CCM06134.1 - 0.16 11.2 4.2 0.42 9.8 0.0 2.5 3 0 0 3 3 3 0 Nineteen complex-related protein 2 DUF848 PF05852.6 CCM06134.1 - 0.24 11.2 7.7 0.17 11.7 2.2 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin PF00804.20 CCM06134.1 - 0.78 9.9 5.2 1.8 8.8 1.6 2.7 1 1 1 2 2 2 0 Syntaxin BLOC1_2 PF10046.4 CCM06134.1 - 1.3 9.2 6.5 0.23 11.6 1.2 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nucleopor_Nup85 PF07575.8 CCM06137.1 - 1.3e-53 182.0 0.0 2.3e-32 111.9 0.0 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin Histone PF00125.19 CCM06138.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCM06138.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CCM06138.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CCM06138.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CCM06138.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CCM06138.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 CCM06139.1 - 4.2e-30 103.6 0.8 6.7e-30 103.0 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCM06139.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCM06139.1 - 0.0013 18.7 1.4 0.0014 18.6 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCM06139.1 - 0.015 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 CCM06139.1 - 0.16 11.2 1.6 0.18 11.0 1.1 1.2 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Nol1_Nop2_Fmu PF01189.12 CCM06140.1 - 1.4e-35 123.0 0.0 1.4e-31 109.9 0.0 2.6 2 1 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CCM06140.1 - 0.015 15.2 0.0 0.045 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 CCM06140.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Abhydrolase_6 PF12697.2 CCM06142.1 - 3.3e-20 72.9 0.0 4e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM06142.1 - 1.2e-08 34.8 0.1 6.7e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM06142.1 - 0.00019 21.1 0.0 0.00051 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Asp PF00026.18 CCM06143.1 - 2.3e-66 224.2 4.6 2.8e-66 223.9 3.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM06143.1 - 1.2e-06 28.6 0.0 1.9e-05 24.6 0.0 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCM06143.1 - 0.2 12.1 1.3 3.5 8.2 0.2 3.2 2 1 0 2 2 2 0 Aspartyl protease TAS2R PF05296.8 CCM06144.1 - 0.038 12.8 3.1 0.091 11.6 2.2 1.6 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) p450 PF00067.17 CCM06147.1 - 1.2e-52 179.0 0.0 6.6e-52 176.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM06148.1 - 3.9e-62 210.2 0.0 2.4e-61 207.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.6 CCM06149.1 - 6.3e-27 94.4 0.1 1.4e-26 93.3 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 CCM06150.1 - 7.2e-64 215.9 0.0 1.9e-63 214.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 CCM06151.1 - 2.5e-19 69.8 0.0 3.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM06151.1 - 7.4e-10 39.0 0.0 9.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM06151.1 - 8.4e-07 29.1 0.0 3.1e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CCM06151.1 - 1.1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM06151.1 - 0.0039 16.6 0.0 0.012 15.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM06151.1 - 0.052 12.2 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCM06151.1 - 0.066 12.1 0.0 1.9 7.3 0.0 2.2 1 1 0 1 1 1 0 Male sterility protein Glyco_hydro_35 PF01301.14 CCM06152.1 - 1.5e-40 139.4 0.0 1.9e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CCM06152.1 - 0.00061 19.0 2.0 0.0014 17.8 0.1 1.9 1 1 1 2 2 2 1 Beta-galactosidase Sperm_Ag_HE2 PF05324.8 CCM06152.1 - 0.095 12.6 0.4 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Sperm antigen HE2 Peptidase_M3 PF01432.15 CCM06153.1 - 2.9e-39 135.3 0.0 3.4e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 MFS_1 PF07690.11 CCM06156.1 - 8.1e-28 97.1 49.3 6.7e-24 84.2 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.5 CCM06156.1 - 0.27 10.9 0.6 0.57 9.8 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 adh_short PF00106.20 CCM06157.1 - 5.5e-25 88.2 0.4 7.7e-25 87.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM06157.1 - 4.5e-21 75.7 0.1 2.8e-20 73.1 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM06157.1 - 1.1e-07 31.7 0.2 6.8e-07 29.1 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CCM06157.1 - 0.069 12.5 0.0 4.3 6.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM06157.1 - 0.092 12.7 0.2 0.28 11.1 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 CCM06157.1 - 0.1 11.6 0.0 0.34 9.9 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glycos_transf_3 PF00591.16 CCM06158.1 - 5.1e-76 255.4 0.0 6.3e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CCM06158.1 - 3.6e-06 26.4 0.0 9.7e-06 25.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Nop16 PF09420.5 CCM06160.1 - 1.6e-16 60.8 0.0 3e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 QCR10 PF09796.4 CCM06161.1 - 6.6e-16 57.7 0.0 7.7e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 CCM06161.1 - 0.048 13.3 1.5 0.11 12.2 1.1 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein HAD_2 PF13419.1 CCM06162.1 - 9.4e-15 55.2 0.0 9.6e-11 42.2 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCM06162.1 - 0.0004 20.0 0.0 0.00073 19.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 CCM06162.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Glyco_hydro_28 PF00295.12 CCM06163.1 - 1.1e-36 126.4 0.2 4.2e-36 124.5 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.8 CCM06163.1 - 0.0041 16.2 2.6 0.0082 15.3 1.8 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.1 CCM06163.1 - 0.053 13.2 9.3 0.14 11.9 6.0 2.1 1 1 0 1 1 1 0 Right handed beta helix region v110 PF01639.12 CCM06164.1 - 0.091 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Viral family 110 zf-C2H2 PF00096.21 CCM06166.1 - 0.00015 21.8 1.4 0.00015 21.8 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM06166.1 - 0.00025 21.1 7.3 0.02 15.2 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCM06166.1 - 0.023 14.6 2.8 0.058 13.3 1.9 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CCM06166.1 - 0.034 13.8 0.6 0.084 12.5 0.4 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type NfeD PF01957.13 CCM06167.1 - 1.2 9.2 4.0 2 8.5 2.2 1.8 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF3328 PF11807.3 CCM06168.1 - 8.5e-14 51.7 0.1 1.1e-13 51.3 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2742 PF10888.3 CCM06168.1 - 0.13 12.1 0.3 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) DUF3328 PF11807.3 CCM06170.1 - 2e-13 50.5 1.2 2.2e-13 50.3 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Synaptobrevin PF00957.16 CCM06172.1 - 0.048 13.2 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Synaptobrevin p450 PF00067.17 CCM06173.1 - 8.3e-66 222.4 0.0 1e-65 222.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mucin PF01456.12 CCM06174.1 - 8.8 6.0 30.3 0.85 9.3 17.8 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Mucin PF01456.12 CCM06175.1 - 1.2 8.8 18.9 2.3 7.9 13.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF607 PF04678.8 CCM06176.1 - 4.6e-42 143.9 0.1 9.6e-42 142.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF607 AA_permease_2 PF13520.1 CCM06177.1 - 4.7e-38 130.8 42.0 4.7e-38 130.8 29.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCM06177.1 - 4.1e-14 51.7 44.3 6e-14 51.2 30.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2649 PF10854.3 CCM06177.1 - 3.1 7.9 9.5 1.9 8.6 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2649) DIOX_N PF14226.1 CCM06178.1 - 5.1e-16 59.2 0.0 1.4e-15 57.8 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM06178.1 - 5.2e-13 49.1 0.0 1.3e-12 47.8 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CCM06179.1 - 1e-15 58.2 0.0 1.9e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM06179.1 - 3.2e-10 40.1 0.0 4.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4449 PF14613.1 CCM06183.1 - 3.2e-29 101.9 2.5 5.9e-29 101.1 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) p450 PF00067.17 CCM06184.1 - 4.2e-66 223.3 0.0 4.9e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 CCM06185.1 - 5e-17 62.3 0.0 8e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM06185.1 - 8e-07 28.8 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM06185.1 - 6.7e-05 22.4 0.1 9.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CCM06185.1 - 8.6e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CCM06185.1 - 0.0026 16.7 0.3 0.0035 16.2 0.2 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CCM06185.1 - 0.011 15.7 0.1 0.034 14.1 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 CCM06185.1 - 0.03 14.4 0.2 0.05 13.7 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 CCM06185.1 - 0.095 11.9 0.2 0.18 11.0 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family Ran_BP1 PF00638.13 CCM06188.1 - 3.4e-17 62.6 0.0 6.9e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain F-box-like PF12937.2 CCM06189.1 - 0.0011 18.6 2.7 0.0027 17.3 1.8 1.7 1 0 0 1 1 1 1 F-box-like DUF4611 PF15387.1 CCM06189.1 - 0.59 10.3 4.2 1.5 8.9 2.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) adh_short PF00106.20 CCM06190.1 - 2.1e-20 73.3 0.0 4.4e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM06190.1 - 9.7e-10 38.3 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCM06190.1 - 1.3e-05 25.1 0.2 3.1e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCM06190.1 - 0.00026 20.5 0.2 0.00056 19.4 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM06190.1 - 0.0042 17.1 0.0 0.014 15.4 0.0 2.0 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 CCM06190.1 - 0.0057 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 CCM06190.1 - 0.051 12.4 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DnaJ PF00226.26 CCM06192.1 - 1.3e-17 63.3 0.5 1.6e-17 62.9 0.3 1.1 1 0 0 1 1 1 1 DnaJ domain p450 PF00067.17 CCM06194.1 - 4e-71 239.9 0.0 5.2e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 CCM06195.1 - 4.1e-42 144.1 42.3 4.1e-42 144.1 29.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM06195.1 - 6.1e-09 34.9 12.0 6.4e-07 28.3 2.6 3.7 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 CCM06195.1 - 0.00048 18.3 4.3 0.00085 17.5 3.0 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector PHF5 PF03660.9 CCM06196.1 - 5.6e-51 171.1 8.0 6.2e-51 170.9 5.5 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 CCM06196.1 - 0.27 11.0 14.7 0.047 13.5 4.6 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 CCM06196.1 - 0.43 10.3 14.3 2.3 7.9 0.3 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 CCM06196.1 - 1.3 8.7 14.1 0.034 13.8 3.7 2.5 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 CCM06196.1 - 6.6 4.2 6.4 7.2 4.1 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 CCM06196.1 - 9.6 6.0 13.0 10 5.9 4.9 2.7 1 1 0 1 1 1 0 zinc-ribbons HECT PF00632.20 CCM06197.1 - 5.8e-85 285.2 0.0 8.3e-85 284.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 CCM06197.1 - 0.055 13.3 2.0 0.5 10.2 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Aminotran_3 PF00202.16 CCM06198.1 - 2.4e-73 246.8 0.0 3.2e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III GCFC PF07842.7 CCM06199.1 - 7.7e-81 271.4 5.8 1.2e-80 270.8 4.0 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 CCM06199.1 - 1.4e-17 63.6 10.2 1.4e-17 63.6 7.1 2.8 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.18 CCM06199.1 - 1.7e-12 46.9 2.3 5.1e-12 45.3 1.6 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CCM06199.1 - 1.2e-07 31.5 5.2 1.3e-06 28.0 1.4 3.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site Ribosomal_S4e PF00900.15 CCM06201.1 - 6.9e-32 108.9 0.2 1.3e-31 108.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 CCM06201.1 - 4.1e-21 74.5 3.8 1.3e-20 72.9 2.8 1.7 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 CCM06201.1 - 1.7e-05 24.1 0.0 3.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CCM06201.1 - 6.9e-05 22.3 4.0 6.9e-05 22.3 2.7 2.1 2 0 0 2 2 2 1 KOW motif E1-E2_ATPase PF00122.15 CCM06202.1 - 2.7e-25 88.7 0.0 5.9e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCM06202.1 - 6.2e-22 79.0 0.0 4.4e-21 76.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCM06202.1 - 7e-20 72.0 0.0 1.3e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCM06202.1 - 1.8e-05 24.5 0.0 4.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCM06202.1 - 0.0039 16.6 0.0 0.0091 15.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCM06202.1 - 0.045 13.3 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase An_peroxidase PF03098.10 CCM06203.1 - 2.6e-68 230.6 0.0 8.9e-55 186.0 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase DUF676 PF05057.9 CCM06205.1 - 1.2e-37 129.3 0.0 1.7e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CCM06205.1 - 7.2e-06 25.6 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CCM06205.1 - 0.0054 16.6 0.1 0.019 14.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM06205.1 - 0.035 13.8 0.0 0.084 12.6 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 CCM06205.1 - 0.071 13.3 0.2 0.4 10.8 0.0 2.1 2 1 1 3 3 3 0 Thioesterase domain PGAP1 PF07819.8 CCM06205.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein p450 PF00067.17 CCM06206.1 - 4.3e-44 150.7 0.0 5.3e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mesd PF10185.4 CCM06207.1 - 0.26 10.9 3.7 0.93 9.1 0.1 2.6 3 0 0 3 3 3 0 Chaperone for wingless signalling and trafficking of LDL receptor NADH_B2 PF14813.1 CCM06208.1 - 0.00025 20.6 0.4 0.00035 20.1 0.2 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 zf-C3HC4_2 PF13923.1 CCM06210.1 - 4.4e-08 33.0 6.4 1.1e-07 31.7 2.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCM06210.1 - 1e-06 28.5 6.3 4.9e-06 26.3 2.0 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCM06210.1 - 2.3e-06 27.2 8.0 1.4e-05 24.6 2.1 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCM06210.1 - 3.1e-06 26.9 14.6 2.3e-05 24.1 10.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCM06210.1 - 4.8e-06 26.1 8.5 5.2e-06 26.0 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCM06210.1 - 5.1e-06 26.1 2.6 5.1e-06 26.1 1.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CCM06210.1 - 2e-05 24.1 7.1 0.00022 20.7 1.4 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CCM06210.1 - 0.018 14.7 0.3 0.038 13.7 0.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FlxA PF14282.1 CCM06210.1 - 0.032 14.1 6.3 0.032 14.1 4.4 2.6 2 1 0 2 2 2 0 FlxA-like protein zf-rbx1 PF12678.2 CCM06210.1 - 0.23 11.5 7.7 0.29 11.2 2.7 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 CCM06210.1 - 0.77 9.3 6.0 0.15 11.6 1.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 UPF0547 PF10571.4 CCM06210.1 - 0.99 9.1 4.5 12 5.7 0.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 IBR PF01485.16 CCM06210.1 - 2.6 8.0 8.9 8.8 6.2 3.4 2.7 2 1 0 2 2 2 0 IBR domain Golgin_A5 PF09787.4 CCM06210.1 - 2.6 6.4 10.4 4.5 5.6 7.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-RING_4 PF14570.1 CCM06210.1 - 5.8 6.5 6.8 21 4.7 1.7 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain MBOAT_2 PF13813.1 CCM06211.1 - 3.4e-21 75.1 1.0 7.9e-21 73.9 0.7 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 CCM06212.1 - 6.6e-37 127.1 0.0 7.2e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 CCM06213.1 - 0.014 15.2 0.0 0.17 11.7 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Nup160 PF11715.3 CCM06213.1 - 0.047 11.8 0.0 0.076 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Pkinase PF00069.20 CCM06214.1 - 1.9e-44 151.7 0.0 3.1e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06214.1 - 4.7e-22 78.3 0.0 2.2e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCM06214.1 - 1.3e-06 27.6 0.0 2.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCM06214.1 - 0.0015 18.3 2.5 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM06214.1 - 0.17 11.4 3.3 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CCM06214.1 - 0.58 8.8 0.0 0.89 8.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1974 PF09317.6 CCM06214.1 - 0.89 8.8 7.0 1.6 8.0 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) TPR_MLP1_2 PF07926.7 CCM06215.1 - 1.4e-20 73.4 14.6 1.4e-20 73.4 10.1 15.5 5 4 7 12 12 12 5 TPR/MLP1/MLP2-like protein DivIC PF04977.10 CCM06215.1 - 0.0049 16.3 0.3 0.0049 16.3 0.2 24.4 19 8 8 27 27 27 5 Septum formation initiator adh_short PF00106.20 CCM06216.1 - 2.2e-08 34.1 0.0 4.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM06216.1 - 0.00086 19.1 0.0 0.00099 18.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ICMT PF04140.9 CCM06217.1 - 3.1e-11 43.3 0.0 1.8e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM06217.1 - 2.7e-09 37.0 0.1 1e-08 35.2 0.1 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CCM06217.1 - 7e-06 24.8 0.0 1.1e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family APH PF01636.18 CCM06218.1 - 1.7e-09 37.7 0.1 2.7e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C2H2 PF00096.21 CCM06219.1 - 2.7e-07 30.5 11.3 0.0032 17.6 0.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM06219.1 - 1.6e-05 24.9 10.1 0.029 14.7 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CCM06219.1 - 0.0015 18.6 6.3 0.87 9.9 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 CCM06219.1 - 0.0016 18.6 9.0 0.32 11.3 1.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 CCM06219.1 - 0.0024 17.9 5.1 1.6 8.9 1.2 3.0 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.1 CCM06219.1 - 0.0086 15.2 2.4 0.79 9.0 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CCM06219.1 - 0.023 14.1 3.0 0.74 9.3 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 CCM06219.1 - 0.039 13.6 1.7 3.7 7.3 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DZR PF12773.2 CCM06219.1 - 0.096 12.5 3.1 6.4 6.6 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_3 PF14369.1 CCM06219.1 - 0.13 12.2 1.3 5.3 7.1 0.1 2.5 2 0 0 2 2 2 0 zinc-finger Ferric_reduct PF01794.14 CCM06220.1 - 5.2e-16 58.8 13.9 5.2e-16 58.8 9.6 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CCM06220.1 - 8.5e-11 41.6 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CCM06220.1 - 2.4e-10 40.5 0.0 2.7e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 CCM06220.1 - 0.061 13.8 0.0 0.7 10.4 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain adh_short PF00106.20 CCM06221.1 - 2e-08 34.3 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM06221.1 - 0.0023 17.7 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Amidase PF01425.16 CCM06222.1 - 1.5e-98 330.5 0.0 1.8e-98 330.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Hexapep PF00132.19 CCM06223.1 - 7.3e-15 53.7 12.1 8.7e-07 28.1 0.6 3.7 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 CCM06223.1 - 4.4e-08 32.9 0.7 4.4e-08 32.9 0.5 4.2 4 1 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep_2 PF14602.1 CCM06223.1 - 1e-07 31.3 8.7 0.017 14.7 0.1 3.6 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 CCM06223.1 - 7.9e-07 28.6 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Nop14 PF04147.7 CCM06223.1 - 1.8e-05 22.9 19.7 1.8e-05 22.9 13.7 3.1 3 0 0 3 3 3 1 Nop14-like family NTP_transf_3 PF12804.2 CCM06223.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Abhydrolase_3 PF07859.8 CCM06224.1 - 3.5e-10 39.8 0.0 5.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM06224.1 - 4.2e-07 29.8 0.0 9.2e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CCM06224.1 - 0.17 10.5 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family PRA1 PF03208.14 CCM06227.1 - 0.23 10.8 8.6 0.31 10.3 6.0 1.1 1 0 0 1 1 1 0 PRA1 family protein ABC2_membrane_3 PF12698.2 CCM06227.1 - 0.28 10.1 5.9 0.37 9.7 4.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2244 PF10003.4 CCM06227.1 - 0.87 8.9 3.7 0.55 9.5 0.2 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4131 PF13567.1 CCM06227.1 - 1.3 8.4 6.7 2.4 7.5 4.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Zn_Tnp_IS1595 PF12760.2 CCM06229.1 - 0.013 15.2 1.2 0.038 13.7 0.9 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 CCM06229.1 - 0.15 12.0 3.4 0.19 11.7 1.0 2.0 2 0 0 2 2 2 0 zinc-finger FYVE_2 PF02318.11 CCM06229.1 - 0.59 10.0 2.5 8.5 6.3 0.1 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger Asp PF00026.18 CCM06230.1 - 1.4e-48 165.8 1.3 1.7e-48 165.4 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCM06230.1 - 0.00026 21.4 1.5 0.039 14.4 0.2 3.4 2 2 0 2 2 2 1 Aspartyl protease Ras PF00071.17 CCM06231.1 - 1.3e-59 200.2 1.0 1.7e-59 199.8 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM06231.1 - 1.8e-15 57.4 0.8 7.1e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCM06231.1 - 3.7e-14 52.3 0.2 4.5e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM06231.1 - 1.7e-06 27.6 0.2 2.4e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCM06231.1 - 0.0041 16.2 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region rve PF00665.21 CCM06231.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Cyclin_N PF00134.18 CCM06232.1 - 1.7e-08 34.1 0.1 8.9e-08 31.7 0.1 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain SOR_SNZ PF01680.12 CCM06234.1 - 4.8e-113 375.8 5.7 7.1e-113 375.3 4.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 CCM06234.1 - 2.1e-10 40.0 2.4 8.3e-07 28.3 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 CCM06234.1 - 0.0005 19.0 0.0 0.78 8.5 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 CCM06234.1 - 0.018 13.9 0.2 0.36 9.7 0.0 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 CCM06234.1 - 0.041 13.1 0.1 1.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein NMO PF03060.10 CCM06234.1 - 0.088 11.9 0.2 0.088 11.9 0.2 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase Bunya_G1 PF03557.10 CCM06234.1 - 0.13 10.0 0.0 0.18 9.5 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 RicinB_lectin_2 PF14200.1 CCM06236.1 - 0.024 14.9 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like NACHT PF05729.7 CCM06237.1 - 1.5e-06 28.0 0.4 7.5e-06 25.7 0.2 2.1 1 1 0 1 1 1 1 NACHT domain F-box-like PF12937.2 CCM06237.1 - 0.032 13.9 0.6 3.5 7.4 0.1 2.6 2 0 0 2 2 2 0 F-box-like GFO_IDH_MocA PF01408.17 CCM06238.1 - 1.2e-26 93.5 0.0 2.3e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCM06238.1 - 4.8e-05 23.1 0.0 9.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 CCM06238.1 - 0.0029 17.9 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 CCM06238.1 - 0.017 15.6 0.0 0.072 13.6 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Fungal_trans PF04082.13 CCM06239.1 - 1.1e-26 93.3 0.0 2.4e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM06239.1 - 9.8e-11 41.3 3.9 2.2e-10 40.2 2.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GRIM-19 PF06212.7 CCM06240.1 - 1.7e-26 92.4 0.0 4.1e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 GRIM-19 protein HMG_box_2 PF09011.5 CCM06240.1 - 2.4e-14 53.4 12.0 1.1e-06 28.8 0.4 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 CCM06240.1 - 3.6e-13 49.5 14.5 3.8e-08 33.4 1.7 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box Lysis_col PF02402.11 CCM06240.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Lysis protein EFP_N PF08207.7 CCM06241.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain APH PF01636.18 CCM06242.1 - 0.0033 17.1 0.8 0.0042 16.8 0.5 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CCM06242.1 - 0.0036 16.4 0.0 0.004 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CCM06242.1 - 0.051 12.6 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 CCM06242.1 - 0.098 11.7 0.0 1.5 7.8 0.0 1.9 1 1 1 2 2 2 0 Ecdysteroid kinase WD40 PF00400.27 CCM06243.1 - 5.6e-68 222.5 19.6 1.2e-11 43.9 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat PD40 PF07676.7 CCM06243.1 - 1.5e-09 37.3 6.1 0.62 9.8 0.0 6.8 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 CCM06243.1 - 2.3e-08 33.7 12.5 1.6e-06 27.6 1.2 4.1 2 2 2 4 4 4 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 CCM06243.1 - 4.5e-07 28.4 0.8 0.015 13.5 0.1 2.7 2 1 1 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.6 CCM06243.1 - 3.6e-05 23.5 0.0 0.62 9.7 0.0 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 CCM06243.1 - 0.036 13.3 16.8 2.2 7.6 0.0 6.5 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature F-box-like PF12937.2 CCM06244.1 - 2.3e-05 24.0 0.9 7.3e-05 22.4 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM06244.1 - 0.013 15.1 0.2 0.078 12.6 0.1 2.3 1 0 0 1 1 1 0 F-box domain Pkinase PF00069.20 CCM06245.1 - 0.082 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Sugar_tr PF00083.19 CCM06248.1 - 9.4e-92 307.9 20.8 9.9e-80 268.2 5.5 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCM06248.1 - 8e-17 60.9 41.1 1.7e-07 30.3 1.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily NAD_binding_4 PF07993.7 CCM06250.1 - 6.3e-30 103.9 0.0 1.1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 CCM06250.1 - 4.5e-26 91.1 0.1 7.2e-23 80.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 CCM06250.1 - 3.9e-09 36.3 0.0 1.3e-08 34.5 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCM06250.1 - 8.4e-06 25.9 0.0 0.00016 21.7 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CCM06250.1 - 0.001 19.0 0.6 0.0021 18.0 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM06250.1 - 0.038 13.6 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 CCM06250.1 - 0.092 11.4 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCM06250.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CCM06250.1 - 0.27 10.1 0.0 1.6 7.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FGGY_N PF00370.16 CCM06251.1 - 0.00029 20.2 0.0 0.4 9.9 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CCM06251.1 - 0.0016 18.1 0.0 0.057 13.0 0.0 2.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain SGS PF05002.10 CCM06251.1 - 0.25 11.1 0.4 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 SGS domain Methyltransf_2 PF00891.13 CCM06253.1 - 5e-24 84.8 0.1 6.2e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase OPT PF03169.10 CCM06254.1 - 1.2e-121 407.2 32.0 7.3e-121 404.5 22.2 2.1 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DNA_pol_viral_N PF00242.12 CCM06255.1 - 7.8 5.4 8.8 9.7 5.1 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Mannosyl_trans2 PF04188.8 CCM06256.1 - 2.4e-58 198.1 21.7 2.9e-58 197.8 15.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Abhydrolase_6 PF12697.2 CCM06257.1 - 6e-08 32.8 0.1 6.7e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM06257.1 - 1.8e-06 27.8 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CCM06257.1 - 0.089 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.3 CCM06257.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_6 PF12697.2 CCM06258.1 - 0.0043 16.9 0.0 0.0047 16.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tri3 PF07428.6 CCM06259.1 - 8.5e-05 21.4 0.0 0.00029 19.6 0.0 1.7 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 Abhydrolase_6 PF12697.2 CCM06260.1 - 4.7e-20 72.4 1.5 2.3e-11 43.9 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM06260.1 - 4.7e-05 23.1 0.0 0.13 12.0 0.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S32 PF05579.8 CCM06263.1 - 0.00074 18.5 0.0 0.0034 16.4 0.1 1.8 2 0 0 2 2 2 1 Equine arteritis virus serine endopeptidase S32 DUF1110 PF06533.7 CCM06263.1 - 0.0013 18.6 0.6 0.0019 18.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1110) Peptidase_S64 PF08192.6 CCM06263.1 - 0.0045 15.3 0.0 0.0064 14.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.1 CCM06263.1 - 0.023 14.6 0.0 0.098 12.6 0.0 2.0 1 1 0 1 1 1 0 Trypsin-like peptidase domain DUF1515 PF07439.6 CCM06263.1 - 0.11 12.2 0.6 0.23 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) BRE1 PF08647.6 CCM06263.1 - 0.31 11.0 2.5 0.51 10.3 1.7 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Ras PF00071.17 CCM06264.1 - 6.9e-52 175.0 0.4 8.5e-52 174.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM06264.1 - 2.6e-13 50.5 0.0 3.7e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCM06264.1 - 2.2e-10 40.0 0.1 2.8e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCM06264.1 - 1.2e-06 28.0 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCM06264.1 - 0.0087 15.2 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF385 PF04075.9 CCM06264.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF385) RRM_1 PF00076.17 CCM06265.1 - 2.3e-13 49.5 0.1 3.2e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM06265.1 - 1.9e-08 34.0 0.0 4e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM06265.1 - 5.4e-08 32.7 0.2 0.00034 20.5 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CCM06265.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Calcipressin COesterase PF00135.23 CCM06269.1 - 9.1e-45 153.3 0.1 1e-44 153.1 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Pkinase PF00069.20 CCM06270.1 - 0.0018 17.4 0.1 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCM06270.1 - 0.0096 15.6 0.0 0.022 14.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Cast PF10174.4 CCM06271.1 - 0.0042 15.2 0.1 0.0065 14.5 0.1 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Como_LCP PF02247.11 CCM06272.1 - 0.14 10.5 0.1 0.21 9.9 0.1 1.2 1 0 0 1 1 1 0 Large coat protein 2OG-FeII_Oxy_2 PF13532.1 CCM06275.1 - 1.4e-21 77.2 0.0 1.8e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CCM06275.1 - 5.1e-05 23.4 0.1 8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily G-patch PF01585.18 CCM06277.1 - 1.1e-07 31.4 0.1 1.1e-07 31.4 0.0 2.8 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 CCM06277.1 - 0.00021 21.0 0.1 0.00021 21.0 0.1 4.2 5 0 0 5 5 5 1 DExH-box splicing factor binding site SR-25 PF10500.4 CCM06277.1 - 0.042 13.3 38.8 0.11 11.9 9.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.6 CCM06277.1 - 0.55 9.8 36.3 0.049 13.3 7.9 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4604 PF15377.1 CCM06277.1 - 0.82 9.8 37.4 1.5 8.9 9.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) SAPS PF04499.10 CCM06277.1 - 7.3 5.1 15.2 0.55 8.8 1.2 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF1777 PF08648.7 CCM06277.1 - 9 5.9 39.1 0.094 12.4 10.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) DNA_ligase_A_M PF01068.16 CCM06278.1 - 7.2e-50 169.1 0.2 2.4e-49 167.4 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCM06278.1 - 5.7e-29 101.1 0.3 6.4e-26 91.2 0.0 3.2 2 1 1 3 3 3 2 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CCM06278.1 - 6.9e-13 48.8 0.0 2.1e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 CCM06278.1 - 7.1e-09 35.6 0.0 0.00014 21.8 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Leu_zip PF15294.1 CCM06278.1 - 0.1 11.6 2.8 0.22 10.5 0.1 2.1 2 0 0 2 2 2 0 Leucine zipper Fork_head PF00250.13 CCM06279.1 - 3.4e-22 78.2 0.0 6.9e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Adaptin_N PF01602.15 CCM06280.1 - 4.9e-131 437.6 5.8 6.1e-131 437.3 4.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CCM06280.1 - 1.5e-22 80.0 0.1 3.2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CCM06280.1 - 0.0001 22.4 2.2 0.23 11.7 0.0 4.4 3 2 0 3 3 3 1 HEAT repeats HEAT PF02985.17 CCM06280.1 - 0.0015 18.4 2.6 30 5.0 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.2 CCM06280.1 - 0.0017 18.2 4.0 0.074 12.8 0.7 3.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 CCM06280.1 - 0.0052 16.3 1.3 0.02 14.5 0.2 2.3 1 1 1 2 2 2 1 TATA-binding protein interacting (TIP20) RIX1 PF08167.7 CCM06280.1 - 0.028 14.0 2.4 0.47 10.1 0.0 3.6 3 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Arm PF00514.18 CCM06280.1 - 0.055 13.3 0.5 89 3.1 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 CCM06280.1 - 0.14 12.1 0.3 3.2 7.7 0.0 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SF3b1 PF08920.5 CCM06281.1 - 2.8e-22 79.3 9.1 2.8e-22 79.3 6.3 2.9 2 1 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CCM06281.1 - 3.5e-12 46.4 11.7 3.5e-05 24.0 0.0 7.4 6 2 1 8 8 8 3 HEAT repeats HEAT PF02985.17 CCM06281.1 - 2.2e-11 42.8 7.5 0.025 14.6 0.0 9.9 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 CCM06281.1 - 1.2e-10 41.5 2.5 0.039 14.4 0.0 8.5 7 2 2 9 9 8 1 HEAT-like repeat Adaptin_N PF01602.15 CCM06281.1 - 4.7e-07 28.5 1.9 0.021 13.1 0.0 3.4 2 1 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CCM06281.1 - 5e-07 30.0 1.4 0.49 10.8 0.0 5.2 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region NUC173 PF08161.7 CCM06281.1 - 0.00046 19.5 0.8 9.1 5.5 0.0 4.6 4 1 1 5 5 5 2 NUC173 domain CLASP_N PF12348.3 CCM06281.1 - 0.0006 19.2 1.8 0.69 9.2 0.0 3.8 3 1 0 3 3 3 2 CLASP N terminal MMS19_C PF12460.3 CCM06281.1 - 0.0054 15.5 0.0 3.5 6.2 0.0 3.7 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 CCM06281.1 - 0.094 12.5 5.7 41 3.9 0.0 5.4 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CCM06281.1 - 0.13 12.1 0.4 9.6 6.2 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pro_isomerase PF00160.16 CCM06282.1 - 2.2e-38 131.9 0.0 4.6e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GTP_CH_N PF12471.3 CCM06283.1 - 3.6e-50 170.2 0.0 5.2e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 CCM06283.1 - 9.3e-15 54.2 0.0 1.3e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribonuclease_3 PF00636.21 CCM06284.1 - 1.4e-39 135.0 0.0 6.6e-20 71.6 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCM06284.1 - 1.3e-23 83.3 0.9 1.2e-10 41.4 0.0 4.2 3 1 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 CCM06284.1 - 5.7e-16 58.4 0.0 1.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM06284.1 - 1.6e-13 50.3 0.1 2e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 CCM06284.1 - 2.2e-13 49.7 0.1 8e-13 47.9 0.1 2.0 1 1 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 CCM06284.1 - 1.7e-11 44.2 0.0 3.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ion_trans_2 PF07885.11 CCM06285.1 - 8.8e-13 47.7 1.1 8.8e-13 47.7 0.7 2.4 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.26 CCM06285.1 - 4.2e-11 42.4 16.2 1.7e-05 24.1 5.9 2.5 2 1 1 3 3 3 2 Ion transport protein Lig_chan PF00060.21 CCM06285.1 - 0.025 14.3 4.2 0.14 11.8 0.1 2.3 2 0 0 2 2 2 0 Ligand-gated ion channel Flavoprotein PF02441.14 CCM06287.1 - 4.7e-40 136.2 0.1 6.7e-40 135.7 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein Homeobox PF00046.24 CCM06288.1 - 0.00031 20.3 0.5 0.0005 19.6 0.3 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 CCM06288.1 - 0.046 13.4 0.7 0.099 12.3 0.5 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF3357 PF11837.3 CCM06289.1 - 0.097 12.5 1.4 0.45 10.3 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Endomucin PF07010.7 CCM06290.1 - 0.033 13.5 0.2 0.044 13.1 0.2 1.2 1 0 0 1 1 1 0 Endomucin Zip PF02535.17 CCM06290.1 - 0.35 9.8 7.9 0.77 8.7 5.5 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter Mob1_phocein PF03637.12 CCM06291.1 - 2e-64 216.4 1.0 2.6e-64 216.1 0.7 1.1 1 0 0 1 1 1 1 Mob1/phocein family SKN1 PF03935.10 CCM06292.1 - 1.8e-06 26.4 0.0 2.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.1 CCM06292.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Neurensin OPT PF03169.10 CCM06293.1 - 1.2e-94 317.9 45.5 1.6e-94 317.5 31.5 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cu_amine_oxid PF01179.15 CCM06294.1 - 1.1e-95 320.8 2.3 2.9e-94 316.1 1.6 2.0 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 CCM06294.1 - 3.6e-13 49.2 0.0 9.8e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 CCM06294.1 - 0.00072 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Longin PF13774.1 CCM06295.1 - 7.3e-17 60.6 0.0 1.3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCM06295.1 - 2.4e-14 52.7 0.7 3.5e-14 52.1 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin DUF2218 PF09981.4 CCM06295.1 - 0.14 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) Peptidase_M50 PF02163.17 CCM06296.1 - 1.1e-12 47.3 0.0 2.3e-11 43.0 0.0 2.6 2 1 0 2 2 2 1 Peptidase family M50 CAAD PF14159.1 CCM06296.1 - 0.54 9.9 5.0 0.2 11.2 0.7 2.3 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Pkinase PF00069.20 CCM06297.1 - 2.9e-12 46.3 0.0 3.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06297.1 - 0.00095 18.3 0.0 0.0019 17.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCM06297.1 - 0.021 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM06297.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 CCM06298.1 - 0.0072 15.5 0.0 0.0084 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Nrap PF03813.9 CCM06300.1 - 4.6e-219 729.5 0.0 7.4e-219 728.8 0.0 1.3 1 1 0 1 1 1 1 Nrap protein TPR_1 PF00515.23 CCM06303.1 - 8.9e-52 170.7 26.9 6.8e-08 31.8 0.0 11.0 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 CCM06303.1 - 2.2e-48 158.3 18.3 7.5e-06 25.4 0.3 10.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 CCM06303.1 - 2.2e-47 158.5 18.3 1.8e-10 40.2 0.0 6.7 3 2 3 7 7 7 6 TPR repeat TPR_8 PF13181.1 CCM06303.1 - 6.5e-36 119.4 17.5 0.00093 18.8 0.0 10.3 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 CCM06303.1 - 1.7e-32 111.2 18.1 1.8e-07 31.0 0.4 6.7 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCM06303.1 - 2.9e-31 107.4 13.2 1.1e-05 25.9 0.0 7.4 3 1 3 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 CCM06303.1 - 4.5e-27 92.0 17.1 0.0044 17.5 0.1 10.8 4 2 7 11 11 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 CCM06303.1 - 1.7e-26 90.1 17.7 0.00011 22.1 0.2 10.4 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 CCM06303.1 - 6.5e-26 88.0 9.4 0.026 14.3 0.2 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_6 PF13174.1 CCM06303.1 - 2.9e-24 83.8 11.6 0.038 14.4 0.0 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 CCM06303.1 - 2.7e-22 78.8 18.3 4.4e-05 23.7 0.2 7.0 5 1 2 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 CCM06303.1 - 4.4e-13 49.1 13.4 4.6e-06 26.6 0.8 4.8 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CCM06303.1 - 1.3e-12 47.4 14.4 0.023 14.5 0.3 5.9 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_15 PF13429.1 CCM06303.1 - 2.6e-09 36.5 10.1 0.00087 18.4 0.3 5.4 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_21 PF09976.4 CCM06303.1 - 2.9e-05 24.0 7.5 0.0063 16.4 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCM06303.1 - 4.2e-05 23.5 1.1 0.0046 17.0 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.1 CCM06303.1 - 0.0002 20.6 12.6 0.044 12.9 0.5 4.5 1 1 4 5 5 5 2 Soluble NSF attachment protein, SNAP DUF2225 PF09986.4 CCM06303.1 - 0.0035 16.8 2.9 1.1 8.6 0.1 3.6 2 2 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.1 CCM06303.1 - 0.052 13.4 0.1 8.9 6.2 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 CCM06303.1 - 0.058 12.1 0.7 9.9 4.8 0.0 2.4 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.4 CCM06303.1 - 0.11 11.8 4.9 11 5.3 0.0 4.5 4 2 2 6 6 6 0 26S proteasome subunit RPN7 TPR_3 PF07720.7 CCM06303.1 - 0.61 9.9 23.2 3.5 7.5 0.7 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCM06303.1 - 2.1 8.4 20.0 10 6.1 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.13 CCM06303.1 - 5.8 6.8 21.1 2.7 7.9 0.0 6.0 6 1 0 7 7 7 0 MIT (microtubule interacting and transport) domain DUF4231 PF14015.1 CCM06304.1 - 0.048 13.6 0.9 0.21 11.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) CRCB PF02537.10 CCM06304.1 - 0.055 13.3 1.2 0.078 12.8 0.1 1.7 2 0 0 2 2 2 0 CrcB-like protein CoatB PF10389.4 CCM06304.1 - 2.6 7.9 7.9 0.45 10.4 2.1 2.2 2 0 0 2 2 2 0 Bacteriophage coat protein B Glyco_transf_20 PF00982.16 CCM06307.1 - 1.1e-144 482.5 0.0 1.4e-144 482.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCM06307.1 - 1e-20 73.6 0.0 1.7e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 CCM06307.1 - 0.053 13.0 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Cellulase PF00150.13 CCM06308.1 - 2e-06 27.2 0.1 3.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_12 PF01670.11 CCM06310.1 - 1.2e-15 57.6 4.8 2.6e-14 53.2 2.6 2.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 DUF2990 PF11693.3 CCM06310.1 - 0.017 14.9 0.0 0.057 13.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) MFS_1 PF07690.11 CCM06311.1 - 1.2e-36 126.1 69.5 2.1e-34 118.8 35.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCM06311.1 - 1.4e-06 26.8 3.2 1.4e-06 26.8 2.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AAA_29 PF13555.1 CCM06314.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 CCM06314.1 - 0.041 12.7 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 CCM06314.1 - 0.057 12.8 0.1 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCM06314.1 - 0.072 12.8 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CCM06314.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CCM06314.1 - 0.13 11.7 0.0 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family MipZ PF09140.6 CCM06314.1 - 0.14 11.2 0.2 0.66 9.0 0.0 1.9 2 0 0 2 2 2 0 ATPase MipZ adh_short PF00106.20 CCM06315.1 - 3.1e-18 66.2 0.2 8.9e-18 64.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM06315.1 - 7.4e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM06315.1 - 2.3e-05 23.9 0.1 5.6e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CCM06315.1 - 2.4e-05 24.2 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM06315.1 - 0.0018 18.3 1.0 0.012 15.5 0.2 2.6 2 1 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 CCM06315.1 - 0.057 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CCM06315.1 - 0.12 11.3 0.1 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 CCM06317.1 - 5.3e-15 55.7 0.4 3.9e-09 36.6 0.2 2.3 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCM06317.1 - 1.1e-06 28.4 0.1 1.9e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM06317.1 - 2.2e-05 24.0 0.5 0.00016 21.2 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CCM06317.1 - 0.0013 18.8 0.1 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 CCM06317.1 - 0.0017 18.4 0.8 0.0032 17.5 0.1 1.9 2 1 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 CCM06317.1 - 0.0041 16.9 0.2 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CCM06317.1 - 0.05 12.4 0.1 0.078 11.8 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 CCM06317.1 - 0.066 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding HMG_box PF00505.14 CCM06318.1 - 1.3e-14 54.1 0.3 2.5e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCM06318.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain F-box-like PF12937.2 CCM06319.1 - 0.0026 17.4 1.0 0.0026 17.4 0.7 2.0 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 CCM06320.1 - 0.063 13.0 0.8 0.55 9.9 0.6 2.3 1 1 0 1 1 1 0 F-box-like domain RPN7 PF10602.4 CCM06321.1 - 1e-41 142.2 1.3 1.5e-41 141.6 0.9 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CCM06321.1 - 5.2e-16 58.8 0.7 1.4e-15 57.4 0.1 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CCM06321.1 - 0.00061 19.5 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 GST_N_3 PF13417.1 CCM06322.1 - 1.4e-12 47.6 0.1 9.3e-11 41.8 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM06322.1 - 1.5e-08 34.3 0.3 5.5e-08 32.5 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCM06322.1 - 2.6e-08 33.7 0.0 5.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCM06322.1 - 2.7e-05 24.0 0.0 8.6e-05 22.4 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCM06322.1 - 6e-05 23.1 0.0 0.00019 21.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCM06322.1 - 0.015 15.7 0.1 0.033 14.6 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SGS PF05002.10 CCM06323.1 - 1.1e-30 105.1 0.9 1.7e-30 104.6 0.6 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CCM06323.1 - 1.3e-07 31.9 0.0 1.9e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 CS domain DHFR_1 PF00186.14 CCM06324.1 - 3e-26 91.9 0.0 5e-26 91.2 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase Metallophos PF00149.23 CCM06325.1 - 4e-18 65.5 0.0 1.1e-12 47.7 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Ribosomal_S17 PF00366.15 CCM06326.1 - 6.1e-31 106.2 1.0 1e-30 105.5 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Retrotrans_gag PF03732.12 CCM06327.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.22 CCM06328.1 - 6.6e-20 71.3 0.1 1.5e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCM06328.1 - 0.091 11.7 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PSP1 PF04468.7 CCM06329.1 - 7.8e-32 109.1 1.7 1.2e-31 108.5 1.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RicinB_lectin_2 PF14200.1 CCM06330.1 - 0.0043 17.3 0.1 0.021 15.1 0.1 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DSHCT PF08148.7 CCM06332.1 - 0.088 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain Cu_amine_oxid PF01179.15 CCM06334.1 - 3.3e-154 513.5 0.0 4.3e-154 513.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 CCM06334.1 - 1.1e-12 47.8 0.0 2.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 CCM06334.1 - 6.4e-07 29.3 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain p450 PF00067.17 CCM06335.1 - 3.2e-38 131.4 0.0 3.4e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PLD_C PF12357.3 CCM06335.1 - 0.027 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D C terminal MFS_1 PF07690.11 CCM06336.1 - 1.4e-49 168.6 39.1 9.1e-47 159.4 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CCM06336.1 - 0.0001 21.9 4.7 0.0028 17.3 0.2 3.7 3 1 0 3 3 3 1 MFS_1 like family OATP PF03137.15 CCM06336.1 - 0.038 12.0 6.6 0.9 7.5 0.3 2.9 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Med9 PF07544.8 CCM06339.1 - 3.4e-08 33.0 1.7 4.3e-08 32.7 1.2 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Sigma70_r1_1 PF03979.9 CCM06339.1 - 0.074 12.9 0.3 0.13 12.1 0.2 1.5 1 1 0 1 1 1 0 Sigma-70 factor, region 1.1 HsbA PF12296.3 CCM06339.1 - 0.08 12.8 1.0 0.23 11.3 0.1 1.9 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Syntaxin-6_N PF09177.6 CCM06339.1 - 0.13 12.6 2.1 0.36 11.2 1.5 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal SlyX PF04102.7 CCM06339.1 - 0.43 10.9 4.0 0.68 10.3 0.3 2.2 2 0 0 2 2 2 0 SlyX DUF802 PF05650.6 CCM06339.1 - 0.71 10.0 6.9 1.1 9.4 2.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF802) HisKA_3 PF07730.8 CCM06339.1 - 1.1 9.6 4.2 0.84 10.0 1.2 1.9 1 1 1 2 2 2 0 Histidine kinase COesterase PF00135.23 CCM06340.1 - 3.3e-99 333.0 0.0 6.2e-99 332.1 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CCM06340.1 - 3.9e-05 22.9 0.0 5.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CCM06340.1 - 6.3e-05 22.6 0.2 0.00016 21.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PCI PF01399.22 CCM06341.1 - 1.5e-06 28.4 0.2 1.5e-06 28.4 0.2 2.5 3 0 0 3 3 3 1 PCI domain DUF3142 PF11340.3 CCM06341.1 - 0.038 13.6 1.4 0.21 11.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3142) FLO_LFY PF01698.11 CCM06341.1 - 1.4 7.6 13.0 3.1 6.5 9.0 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4407 PF14362.1 CCM06341.1 - 5.1 5.9 22.8 3.4 6.5 10.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.20 CCM06342.1 - 1.9e-13 50.1 0.1 2.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06342.1 - 1.1e-07 31.1 0.0 1.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCM06342.1 - 0.0023 17.0 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCM06342.1 - 0.0039 16.9 0.1 0.0075 16.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM06342.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 CCM06342.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Nucleoplasmin PF03066.10 CCM06344.1 - 0.006 16.1 4.5 0.0078 15.7 3.1 1.2 1 0 0 1 1 1 1 Nucleoplasmin Nop14 PF04147.7 CCM06344.1 - 0.031 12.2 4.2 0.033 12.1 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.6 CCM06344.1 - 0.035 13.3 19.0 0.045 13.0 13.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 CCM06344.1 - 0.06 12.6 5.7 0.082 12.1 3.9 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 CCM06344.1 - 0.2 11.8 13.8 0.36 11.0 9.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 CCM06344.1 - 0.34 9.6 9.7 0.52 8.9 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 CCM06344.1 - 0.45 8.4 2.1 0.43 8.5 1.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TEX19 PF15553.1 CCM06344.1 - 0.46 10.3 4.9 0.76 9.6 3.4 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Daxx PF03344.10 CCM06344.1 - 0.79 8.1 7.5 0.96 7.8 5.2 1.1 1 0 0 1 1 1 0 Daxx Family Myc_N PF01056.13 CCM06344.1 - 1.2 8.1 3.1 1.6 7.7 2.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 CCM06344.1 - 4.2 5.1 13.0 5.1 4.8 9.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 CCM06344.1 - 7.4 6.1 9.8 11 5.6 6.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region F-box PF00646.28 CCM06345.1 - 0.0012 18.4 3.7 0.0012 18.4 0.2 2.9 3 0 0 3 3 3 1 F-box domain Glyco_hydro_44 PF12891.2 CCM06345.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 44 LRRNT_2 PF08263.7 CCM06350.1 - 0.048 13.6 1.8 0.97 9.4 0.0 2.9 2 1 0 2 2 2 0 Leucine rich repeat N-terminal domain zf-C2H2_4 PF13894.1 CCM06350.1 - 0.052 13.8 0.3 0.052 13.8 0.2 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM06350.1 - 0.17 12.2 0.3 0.17 12.2 0.2 4.1 4 1 0 4 4 4 0 Zinc finger, C2H2 type SAP30_Sin3_bdg PF13867.1 CCM06352.1 - 2.1e-06 27.4 0.3 4.2e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Med3 PF11593.3 CCM06352.1 - 6 5.9 6.0 6.8 5.8 4.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sel1 PF08238.7 CCM06354.1 - 2.1e-17 63.1 6.6 1.9e-07 31.4 0.7 3.6 3 0 0 3 3 3 3 Sel1 repeat TPR_16 PF13432.1 CCM06354.1 - 0.084 13.5 0.2 0.21 12.2 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCM06354.1 - 0.28 11.1 1.1 37 4.5 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PBP PF01161.15 CCM06355.1 - 1.2e-17 64.1 0.2 2.1e-17 63.3 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DNA_topoisoIV PF00521.15 CCM06356.1 - 3.3e-125 418.3 0.0 7.5e-125 417.1 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CCM06356.1 - 5.8e-36 123.3 2.7 1.3e-35 122.2 1.9 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CCM06356.1 - 1.6e-15 56.8 0.0 7.5e-15 54.7 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CCM06356.1 - 2.8e-08 33.4 0.0 1e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Secretin_N PF03958.12 CCM06356.1 - 0.056 13.6 1.1 1.7 8.9 0.0 3.3 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain UPF0016 PF01169.14 CCM06357.1 - 7.8e-44 147.7 17.1 5.2e-22 77.7 3.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 CCM06357.1 - 0.034 13.5 0.4 0.034 13.5 0.3 2.4 2 0 0 2 2 2 0 Integral membrane protein TerC family Peptidase_M17 PF00883.16 CCM06358.1 - 9.9e-78 261.1 0.1 1.5e-77 260.5 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CCM06358.1 - 8.9e-08 31.9 0.5 2e-07 30.8 0.3 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain F-box PF00646.28 CCM06359.1 - 0.0016 17.9 0.0 0.0058 16.2 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCM06359.1 - 0.029 14.1 0.0 0.097 12.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like FHA PF00498.21 CCM06360.1 - 9.4e-16 57.6 0.0 1.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF1664 PF07889.7 CCM06360.1 - 2.2 8.0 10.2 0.17 11.6 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Mac PF12464.3 CCM06360.1 - 3.8 7.5 6.5 0.48 10.4 0.6 2.4 2 0 0 2 2 2 0 Maltose acetyltransferase NPV_P10 PF05531.7 CCM06360.1 - 4.8 7.5 10.0 31 4.9 0.0 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Cation_ATPase_C PF00689.16 CCM06361.1 - 0.012 15.2 1.5 0.012 15.2 1.0 1.8 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus BTB PF00651.26 CCM06362.1 - 7.2e-22 77.4 0.2 1.4e-10 41.1 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain HMA PF00403.21 CCM06362.1 - 0.087 12.9 0.5 0.16 12.1 0.4 1.5 1 0 0 1 1 1 0 Heavy-metal-associated domain DUF1752 PF08550.5 CCM06363.1 - 7e-07 28.7 9.4 1.2e-06 27.9 6.5 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) BTB PF00651.26 CCM06364.1 - 9.1e-20 70.7 0.0 1.6e-12 47.3 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain CAP_GLY PF01302.20 CCM06365.1 - 7.5e-19 67.2 0.8 1.3e-18 66.4 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF904 PF06005.7 CCM06365.1 - 0.0015 18.8 5.8 0.0015 18.8 4.0 8.8 5 3 1 6 6 6 2 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 CCM06365.1 - 0.013 14.6 40.3 0.0067 15.6 2.6 5.4 2 2 4 6 6 6 0 Reovirus sigma C capsid protein DUF2870 PF11069.3 CCM06365.1 - 0.8 9.7 9.5 0.065 13.2 0.4 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Shugoshin_N PF07558.6 CCM06365.1 - 5.8 6.7 15.6 1.9 8.2 1.8 4.5 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region zf-CCHC_4 PF14392.1 CCM06365.1 - 7.5 6.3 8.3 15 5.3 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle CLASP_N PF12348.3 CCM06366.1 - 5.7e-23 81.4 0.0 8.2e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal SAP PF02037.22 CCM06367.1 - 0.00026 20.3 0.2 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.7 CCM06367.1 - 0.0056 16.4 0.7 0.012 15.3 0.1 1.9 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain HeH PF12949.2 CCM06367.1 - 0.039 13.5 1.0 0.075 12.5 0.7 1.4 1 0 0 1 1 1 0 HeH/LEM domain CCT_2 PF09425.5 CCM06367.1 - 0.2 11.2 0.2 0.2 11.2 0.1 2.4 2 0 0 2 2 2 0 Divergent CCT motif CBFB_NFYA PF02045.10 CCM06368.1 - 3e-28 98.1 7.6 3e-28 98.1 5.3 2.1 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_S13 PF00416.17 CCM06370.1 - 1.9e-41 140.8 1.4 2.4e-41 140.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCM06370.1 - 0.0079 14.7 0.0 0.0081 14.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CCM06370.1 - 0.019 14.9 0.2 0.053 13.5 0.1 1.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif Rotavirus_VP1 PF12289.3 CCM06370.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Rotavirus VP1 structural protein PP28 PF10252.4 CCM06370.1 - 0.13 12.3 0.3 0.32 11.0 0.2 1.7 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 tRNA-synt_2c PF01411.14 CCM06371.1 - 3.4e-197 656.1 0.0 4.5e-197 655.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CCM06371.1 - 4.6e-16 58.4 1.4 4.1e-15 55.3 0.3 2.5 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CCM06371.1 - 0.0013 18.4 1.8 0.0013 18.4 1.2 2.6 2 0 0 2 2 2 1 DHHA1 domain RPW8 PF05659.6 CCM06371.1 - 0.033 13.7 0.4 0.74 9.3 0.0 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3328 PF11807.3 CCM06372.1 - 9e-58 195.5 0.6 1.1e-57 195.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 CCM06373.1 - 2.4e-32 112.4 4.9 2.7e-32 112.2 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 CCM06374.1 - 6.8e-07 29.1 0.0 8.2e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_C50 PF03568.12 CCM06375.1 - 6.7e-97 324.5 0.0 9.2e-97 324.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 CCM06375.1 - 8.3e-05 22.4 3.3 0.45 10.4 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat CHAT PF12770.2 CCM06375.1 - 0.0024 17.0 0.0 0.13 11.3 0.0 2.4 1 1 0 1 1 1 1 CHAT domain TPR_2 PF07719.12 CCM06375.1 - 0.0038 17.0 2.9 4.6 7.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCM06375.1 - 0.013 15.1 2.3 0.58 9.8 0.1 3.0 1 1 1 2 2 2 0 TPR repeat TPR_10 PF13374.1 CCM06375.1 - 0.014 15.3 2.5 0.16 11.9 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CCM06375.1 - 0.022 14.8 0.4 0.083 13.0 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CCM06375.1 - 0.12 13.1 5.1 8.1 7.3 0.3 4.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Ric8 PF10165.4 CCM06376.1 - 8.2e-73 245.7 0.0 1.3e-72 245.1 0.0 1.3 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Med10 PF09748.4 CCM06376.1 - 3.5e-10 39.7 0.0 8.7e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex RRM_1 PF00076.17 CCM06377.1 - 8.3e-45 150.2 0.0 2.4e-22 78.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM06377.1 - 6.9e-33 112.4 0.0 2.8e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCM06377.1 - 5.2e-21 74.2 0.0 2e-09 37.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCM06377.1 - 0.013 15.2 0.0 0.089 12.5 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 CCM06377.1 - 0.014 14.9 0.0 0.3 10.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) GDI PF00996.13 CCM06378.1 - 9.8e-58 195.5 0.0 1.3e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CCM06378.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ING PF12998.2 CCM06380.1 - 5.5e-09 36.2 0.8 1.5e-07 31.6 0.5 2.4 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Nuf2 PF03800.9 CCM06381.1 - 5.9e-29 100.9 0.0 1.7e-28 99.4 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family DUF812 PF05667.6 CCM06381.1 - 0.0019 16.8 33.0 0.0024 16.4 22.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GAS PF13851.1 CCM06381.1 - 0.011 14.9 45.1 0.094 11.9 3.8 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 CCM06381.1 - 0.032 14.5 35.2 0.16 12.3 0.3 4.4 2 2 2 4 4 4 0 Protein of unknown function (DUF972) Spc7 PF08317.6 CCM06381.1 - 1.8 7.1 46.9 0.58 8.7 7.9 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 CCM06381.1 - 1.8 8.1 50.4 2.9 7.4 21.0 2.6 1 1 1 2 2 2 0 IncA protein Filament PF00038.16 CCM06381.1 - 2.1 7.7 45.8 2.1 7.7 19.0 3.0 1 1 1 2 2 2 0 Intermediate filament protein APG6 PF04111.7 CCM06381.1 - 3.5 6.5 46.8 0.31 10.0 5.0 3.1 1 1 1 3 3 3 0 Autophagy protein Apg6 Atg14 PF10186.4 CCM06381.1 - 3.7 6.4 43.4 1.1 8.1 8.9 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 N_NLPC_P60 PF12912.2 CCM06381.1 - 3.9 7.5 6.5 3.7 7.6 0.1 3.0 3 1 0 3 3 3 0 NLPC_P60 stabilising domain, N term Reo_sigmaC PF04582.7 CCM06381.1 - 7.4 5.6 12.1 4.2 6.4 3.9 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF148 PF02520.12 CCM06381.1 - 8.2 6.2 26.0 0.71 9.6 5.4 4.2 3 1 1 4 4 4 0 Domain of unknown function DUF148 DEAD PF00270.24 CCM06382.1 - 3.4e-18 65.7 0.0 2e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM06382.1 - 3.3e-17 62.0 0.1 6.6e-16 57.9 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 CCM06382.1 - 1.2e-13 50.6 0.0 3.1e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 RQC domain DegV PF02645.11 CCM06382.1 - 0.21 10.6 0.0 1.7 7.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein, DegV family COG1307 FUSC PF04632.7 CCM06383.1 - 7.5e-09 34.5 2.8 7.5e-09 34.5 2.0 2.2 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF2421 PF10334.4 CCM06383.1 - 4.4e-07 29.7 2.8 7.8e-07 28.9 0.2 2.5 2 2 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 CCM06383.1 - 0.095 11.3 0.1 0.095 11.3 0.1 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter DEAD PF00270.24 CCM06384.1 - 1.5e-43 148.2 0.0 1.2e-42 145.2 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCM06384.1 - 1.2e-22 79.5 0.0 3.6e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM06384.1 - 0.00061 19.6 0.0 0.2 11.5 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCM06384.1 - 0.0028 17.6 0.0 0.0083 16.0 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 CCM06384.1 - 0.0046 15.4 0.2 0.064 11.6 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) DUF2608 PF11019.3 CCM06384.1 - 0.012 14.5 0.1 0.026 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) CMS1 PF14617.1 CCM06384.1 - 0.47 9.4 9.5 0.87 8.6 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Usp PF00582.21 CCM06384.1 - 0.88 9.7 6.5 2.4 8.3 4.5 1.7 1 0 0 1 1 1 0 Universal stress protein family RR_TM4-6 PF06459.7 CCM06384.1 - 2.8 7.7 10.8 4.6 7.0 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GalP_UDP_transf PF01087.17 CCM06385.1 - 9.4e-64 214.8 0.0 4e-63 212.7 0.0 1.8 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CCM06385.1 - 9.9e-47 158.5 0.0 2e-46 157.5 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 CCM06385.1 - 0.015 15.8 2.3 0.1 13.1 0.6 2.8 3 1 0 3 3 3 0 HIT domain DcpS_C PF11969.3 CCM06385.1 - 0.54 10.5 2.4 2.1 8.5 0.6 2.5 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding SLT PF01464.15 CCM06386.1 - 9.1e-12 44.5 0.0 1.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain DAG1 PF05454.6 CCM06386.1 - 0.012 14.7 0.0 0.035 13.2 0.0 1.7 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF588 PF04535.7 CCM06386.1 - 0.041 13.4 5.6 0.31 10.6 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF588) Herpes_gE PF02480.11 CCM06386.1 - 0.098 10.9 0.0 0.19 9.9 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1180 PF06679.7 CCM06386.1 - 0.17 11.7 1.3 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1485 PF07364.7 CCM06387.1 - 0.099 11.8 0.1 1.6 7.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1485) MFS_1 PF07690.11 CCM06389.1 - 4.1e-42 144.1 37.0 4.1e-42 144.1 25.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CCM06389.1 - 3.1e-08 32.2 4.9 4.6e-06 25.1 1.1 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) T2SM PF04612.7 CCM06389.1 - 0.13 12.0 0.1 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Redoxin PF08534.5 CCM06390.1 - 2.1e-38 131.1 0.0 2.4e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCM06390.1 - 6.8e-14 51.6 0.0 8.4e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family LPAM_1 PF08139.7 CCM06391.1 - 8.4 6.7 9.3 0.27 11.5 2.3 1.6 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site DUF2392 PF10288.4 CCM06392.1 - 4.5e-10 39.8 0.0 1.5e-07 31.6 0.0 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) Gin PF10764.4 CCM06392.1 - 0.062 13.0 0.1 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin Aminotran_5 PF00266.14 CCM06393.1 - 3.5e-13 49.0 0.0 2.6e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCM06393.1 - 7.3e-06 25.1 0.0 4.8e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CCM06393.1 - 0.0027 16.8 0.0 0.46 9.4 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_S11 PF00411.14 CCM06395.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S11 Sugar_tr PF00083.19 CCM06396.1 - 3.9e-107 358.6 22.8 4.4e-107 358.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM06396.1 - 5.5e-20 71.3 38.4 6.5e-19 67.8 21.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NUFIP1 PF10453.4 CCM06397.1 - 0.025 14.0 1.1 7.4 6.1 0.0 3.0 3 0 0 3 3 3 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) CTP_transf_3 PF02348.14 CCM06397.1 - 0.094 12.3 0.2 5.4 6.5 0.0 2.3 1 1 1 2 2 2 0 Cytidylyltransferase DUF3328 PF11807.3 CCM06398.1 - 7e-52 176.2 0.4 8.4e-52 175.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) YqhR PF11085.3 CCM06400.1 - 0.017 14.6 3.2 0.85 9.1 0.1 2.3 2 0 0 2 2 2 0 Conserved membrane protein YqhR Sulfate_tra_GLY PF13792.1 CCM06400.1 - 0.21 11.2 3.9 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Sulfate transporter N-terminal domain with GLY motif F-box PF00646.28 CCM06401.1 - 0.064 12.9 0.0 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.1 CCM06401.1 - 0.13 11.9 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 CCM06401.1 - 0.32 10.7 5.2 0.07 12.8 1.0 2.0 2 0 0 2 2 2 0 F-box-like Ammonium_transp PF00909.16 CCM06402.1 - 1.9e-105 352.5 24.3 2.4e-105 352.3 16.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family LIP PF03583.9 CCM06402.1 - 0.014 14.5 1.9 0.027 13.6 1.3 1.4 1 0 0 1 1 1 0 Secretory lipase Innate_immun PF12782.2 CCM06403.1 - 0.079 12.1 5.5 0.11 11.7 3.8 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family WD40 PF00400.27 CCM06407.1 - 7.7e-130 418.7 50.2 1.9e-13 49.7 0.4 10.1 10 0 0 10 10 10 10 WD domain, G-beta repeat PQQ_3 PF13570.1 CCM06407.1 - 3.4e-12 46.1 8.5 1.9 8.8 0.0 9.4 9 1 1 10 10 10 2 PQQ-like domain Nucleoporin_N PF08801.6 CCM06407.1 - 1.6e-09 37.0 37.9 0.056 12.1 0.1 9.6 1 1 7 10 10 10 7 Nup133 N terminal like PD40 PF07676.7 CCM06407.1 - 1.4e-07 31.0 0.1 28 4.5 0.0 8.2 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat DUF4072 PF13284.1 CCM06407.1 - 1.7e-07 31.3 7.7 13 6.0 0.0 8.5 9 0 0 9 9 9 0 Domain of unknown function (DUF4072) DUF1598 PF07643.6 CCM06407.1 - 0.00079 19.4 0.1 1e+02 2.9 0.0 6.1 7 0 0 7 7 7 0 Protein of unknown function (DUF1598) AsnC_trans_reg PF01037.16 CCM06407.1 - 0.0013 18.3 6.4 7.2 6.3 0.0 6.7 9 0 0 9 9 9 1 AsnC family T2SJ PF11612.3 CCM06407.1 - 0.0018 18.0 2.3 14 5.3 0.1 4.8 2 1 3 5 5 5 0 Type II secretion system (T2SS), protein J DUF727 PF05303.7 CCM06407.1 - 0.0095 15.7 9.3 10 5.9 0.0 7.3 8 2 2 10 10 10 1 Protein of unknown function (DUF727) DUF422 PF04240.7 CCM06407.1 - 0.13 11.6 0.3 22 4.3 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF422) Nup160 PF11715.3 CCM06407.1 - 0.14 10.2 33.4 0.53 8.3 0.6 8.5 1 1 7 8 8 8 0 Nucleoporin Nup120/160 CHAP PF05257.11 CCM06407.1 - 1.8 8.2 23.5 4.4 6.9 1.4 7.2 3 2 3 6 6 6 0 CHAP domain AAA_16 PF13191.1 CCM06409.1 - 0.00079 19.4 1.7 0.0021 18.0 0.1 2.5 3 1 0 3 3 3 1 AAA ATPase domain PARP PF00644.15 CCM06411.1 - 3.3e-05 23.3 0.0 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 CCM06412.1 - 1.5e-32 112.5 0.0 2.3e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.6 CCM06414.1 - 1.3e-26 93.1 1.9 2.2e-26 92.4 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1768) RPAP2_Rtr1 PF04181.8 CCM06415.1 - 0.026 14.6 4.6 8.7 6.5 0.1 3.1 3 0 0 3 3 3 0 Rtr1/RPAP2 family Ecl1 PF12855.2 CCM06415.1 - 0.58 9.4 6.6 0.9 8.8 0.5 2.4 2 0 0 2 2 2 0 Life-span regulatory factor OHA PF14418.1 CCM06416.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 OST-HTH Associated domain MFS_Mycoplasma PF07672.8 CCM06416.1 - 0.1 11.7 1.6 0.12 11.4 0.9 1.4 1 1 0 1 1 1 0 Mycoplasma MFS transporter DUF2427 PF10348.4 CCM06416.1 - 0.13 11.8 1.8 5.2 6.6 0.4 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF2165 PF09933.4 CCM06416.1 - 0.14 11.9 0.9 0.66 9.6 0.1 2.2 1 1 2 3 3 3 0 Predicted small integral membrane protein (DUF2165) OppC_N PF12911.2 CCM06416.1 - 3.7 6.9 5.3 0.47 9.8 0.3 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C PARP PF00644.15 CCM06417.1 - 2.4e-13 50.0 1.8 1.1e-09 37.9 0.1 2.8 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Aminotran_1_2 PF00155.16 CCM06418.1 - 7.2e-25 87.7 0.0 8.7e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CCM06418.1 - 1.2e-11 43.8 0.0 1.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase RVT_1 PF00078.22 CCM06420.1 - 0.099 11.9 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) SET PF00856.23 CCM06421.1 - 4.1e-12 46.6 0.1 2.9e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.7 CCM06421.1 - 0.0013 19.0 0.0 0.0096 16.2 0.0 2.3 2 0 0 2 2 2 1 SAF domain C2 PF00168.25 CCM06422.1 - 1.8e-08 34.1 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain Peroxidase_2 PF01328.12 CCM06423.1 - 1.4e-25 89.6 0.2 3.1e-25 88.5 0.1 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 polyprenyl_synt PF00348.12 CCM06424.1 - 1.2e-50 171.7 0.0 1.5e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Cupin_2 PF07883.6 CCM06425.1 - 5.1e-26 89.9 0.2 4.2e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CCM06425.1 - 5.7e-26 90.6 0.0 5.2e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 CCM06425.1 - 5.3e-06 25.7 0.0 0.00025 20.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 CCM06425.1 - 1.3e-05 24.9 0.2 3.2e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 CCM06425.1 - 0.0006 19.4 0.0 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 CCM06425.1 - 0.0069 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 CCM06425.1 - 0.031 14.2 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 ARD/ARD' family 2OG-FeII_Oxy_5 PF13759.1 CCM06425.1 - 0.045 14.0 0.1 14 6.0 0.1 3.6 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase Cupin_6 PF12852.2 CCM06425.1 - 0.047 13.2 0.0 0.33 10.5 0.0 2.3 3 0 0 3 3 3 0 Cupin GPI PF06560.6 CCM06425.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Asp PF00026.18 CCM06426.1 - 2.2e-28 99.4 1.3 2.2e-28 99.4 0.9 2.5 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCM06426.1 - 8.1e-06 26.2 0.2 2.8e-05 24.5 0.2 2.0 1 0 0 1 1 1 1 Aspartyl protease Trp_oprn_chp PF09534.5 CCM06426.1 - 0.024 14.2 2.5 0.043 13.4 1.7 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Exo_endo_phos PF03372.18 CCM06427.1 - 3.8e-06 27.0 0.0 8.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Adaptin_N PF01602.15 CCM06428.1 - 4.4e-114 381.6 0.1 1.1e-113 380.3 0.1 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCM06428.1 - 4.2e-11 42.9 5.5 0.00023 21.3 0.0 4.5 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 CCM06428.1 - 7.6e-06 25.5 8.1 0.34 11.0 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 CCM06428.1 - 3.8e-05 24.0 3.9 0.19 12.2 0.0 4.3 4 0 0 4 4 4 2 HEAT-like repeat Cohesin_HEAT PF12765.2 CCM06428.1 - 0.0017 18.2 0.4 0.49 10.4 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 CCM06428.1 - 0.11 12.4 5.0 9.7 5.9 0.1 3.3 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HTH_36 PF13730.1 CCM06428.1 - 0.12 12.4 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Nop14 PF04147.7 CCM06428.1 - 2.7 5.8 18.4 1.8 6.4 11.3 1.7 2 0 0 2 2 2 0 Nop14-like family p450 PF00067.17 CCM06429.1 - 3e-46 157.9 0.0 1.7e-42 145.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 ICMT PF04140.9 CCM06430.1 - 9.6e-14 51.3 7.4 1.1e-13 51.1 1.4 2.9 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM06430.1 - 2.4e-11 43.6 3.0 2.4e-11 43.6 2.1 2.3 2 1 1 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CCM06430.1 - 0.00013 20.6 0.8 0.00017 20.2 0.6 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sina PF03145.11 CCM06432.1 - 0.0015 18.2 4.9 0.031 13.9 1.6 2.2 2 0 0 2 2 2 2 Seven in absentia protein family Neisseria_TspB PF05616.8 CCM06432.1 - 0.96 7.7 4.1 1.5 7.0 2.9 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein zf-Di19 PF05605.7 CCM06432.1 - 6.7 6.9 8.8 26 5.0 0.4 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Kisspeptin PF15152.1 CCM06432.1 - 6.9 7.4 6.5 35 5.1 0.8 3.0 3 0 0 3 3 3 0 Kisspeptin Aconitase PF00330.15 CCM06433.1 - 7.7e-71 238.9 0.1 3.3e-42 144.5 0.0 3.1 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCM06433.1 - 4e-19 69.0 0.0 8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 CCM06433.1 - 0.0088 14.6 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Aconitase_2_N PF06434.8 CCM06433.1 - 0.063 12.6 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus TauD PF02668.11 CCM06434.1 - 6.7e-42 143.9 0.0 8.7e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 CCM06434.1 - 0.0026 16.7 0.1 0.014 14.3 0.0 1.9 2 0 0 2 2 2 1 CsiD 2OG-FeII_Oxy_3 PF13640.1 CCM06434.1 - 0.061 13.8 0.4 0.53 10.8 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF2678 PF10856.3 CCM06435.1 - 6.9 6.4 7.3 5.7 6.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) Methyltransf_2 PF00891.13 CCM06436.1 - 3.2e-32 111.6 0.0 5.4e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 CCM06436.1 - 3.8e-08 33.9 0.0 8.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HTH_IclR PF09339.5 CCM06436.1 - 0.0057 16.2 0.0 0.5 10.0 0.0 2.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain Methyltransf_23 PF13489.1 CCM06436.1 - 0.029 14.0 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 CCM06436.1 - 0.034 13.7 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CCM06436.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HTH_24 PF13412.1 CCM06436.1 - 0.16 11.4 0.0 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding FMO-like PF00743.14 CCM06437.1 - 9.4e-21 73.5 0.2 2.4e-19 68.9 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCM06437.1 - 1.1e-14 54.9 0.0 2.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM06437.1 - 1.6e-09 37.1 0.1 2.4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM06437.1 - 3.1e-06 27.1 0.0 1.1e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM06437.1 - 0.0015 18.8 0.0 0.12 12.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM06437.1 - 0.0051 15.7 0.1 0.029 13.2 0.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 CCM06437.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain COesterase PF00135.23 CCM06438.1 - 7.4e-68 229.5 0.5 1.2e-46 159.5 0.0 2.2 1 1 1 2 2 2 2 Carboxylesterase family p450 PF00067.17 CCM06438.1 - 9.9e-11 40.8 0.0 1.3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 CCM06438.1 - 0.00025 20.6 0.3 0.00075 19.1 0.1 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCM06438.1 - 0.0014 17.8 0.1 0.0025 17.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_GDSL PF00657.17 CCM06439.1 - 1.5e-13 51.1 0.5 1.9e-13 50.7 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Adap_comp_sub PF00928.16 CCM06440.1 - 3.1e-86 288.7 0.2 4e-86 288.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCM06440.1 - 5.9e-05 22.8 0.5 0.00017 21.3 0.4 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain ABM PF03992.11 CCM06440.1 - 0.043 13.8 0.2 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase CENP-C_C PF11699.3 CCM06441.1 - 1.7e-28 98.4 1.6 2.9e-28 97.6 1.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 CCM06441.1 - 4.6e-05 22.8 0.0 9.1e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CCM06441.1 - 0.0033 17.1 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Arteri_nucleo PF01481.11 CCM06441.1 - 0.048 13.7 0.6 1.7 8.7 0.1 2.9 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein PAP_assoc PF03828.14 CCM06442.1 - 3.6e-18 65.2 0.1 1.7e-17 63.0 0.1 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CCM06442.1 - 1.1e-06 28.8 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain F-box PF00646.28 CCM06443.1 - 0.00027 20.4 1.6 0.0018 17.8 0.0 2.8 3 1 0 3 3 3 1 F-box domain F-box-like PF12937.2 CCM06443.1 - 0.00073 19.2 0.1 0.0018 17.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 CCM06445.1 - 3.8e-10 39.3 0.0 5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06445.1 - 8.9e-07 28.2 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCM06445.1 - 0.026 13.5 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family E2R135 PF11570.3 CCM06445.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 PLU-1 PF08429.6 CCM06448.1 - 5.7e-46 156.9 6.7 5.7e-46 156.9 4.6 2.3 2 1 1 3 3 3 2 PLU-1-like protein JmjC PF02373.17 CCM06448.1 - 1.7e-41 141.0 0.4 1.7e-41 141.0 0.3 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 CCM06448.1 - 8.2e-20 70.4 0.0 2.1e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 CCM06448.1 - 2.7e-16 58.7 0.1 5.9e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 CCM06448.1 - 5.5e-16 58.3 11.2 1.8e-15 56.6 7.7 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 CCM06448.1 - 7.5e-16 57.5 40.8 7.1e-11 41.6 6.1 4.6 4 0 0 4 4 4 3 PHD-finger Prok-RING_1 PF14446.1 CCM06448.1 - 0.021 14.5 28.5 0.05 13.3 5.2 3.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CCM06448.1 - 7.6 5.9 24.0 0.74 9.1 1.1 4.0 4 0 0 4 4 4 0 PHD-finger NST1 PF13945.1 CCM06449.1 - 5.7e-56 189.6 2.2 5.7e-56 189.6 1.5 4.5 2 1 2 4 4 4 1 Salt tolerance down-regulator E1-E2_ATPase PF00122.15 CCM06450.1 - 1.3e-23 83.2 0.0 1.3e-23 83.2 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCM06450.1 - 2.8e-17 63.8 0.0 1.3e-16 61.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCM06450.1 - 4.1e-11 43.4 0.1 9e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCM06450.1 - 1.9e-06 27.7 0.0 8.1e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCM06450.1 - 9e-05 22.1 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Staphylcoagulse PF04022.7 CCM06450.1 - 6.8 6.1 6.4 3.4 7.1 0.8 2.5 2 0 0 2 2 2 0 Staphylocoagulase repeat FMO-like PF00743.14 CCM06451.1 - 5.7e-25 87.5 0.0 1e-24 86.6 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCM06451.1 - 5.9e-22 78.7 0.0 1.6e-21 77.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM06451.1 - 2.5e-11 43.1 0.0 2.3e-08 33.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCM06451.1 - 3.5e-10 40.0 0.0 2.5e-07 30.7 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCM06451.1 - 6.2e-05 23.1 0.0 0.0049 16.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 CCM06451.1 - 0.00032 20.6 0.1 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.1 CCM06451.1 - 0.00074 19.3 0.6 0.63 9.7 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 CCM06451.1 - 0.0013 19.0 0.0 3.3 8.1 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CCM06451.1 - 0.0038 16.9 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 CCM06451.1 - 0.011 14.6 0.2 1.2 8.0 0.0 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CCM06451.1 - 0.02 14.4 0.0 0.057 12.9 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CPSase_L_chain PF00289.17 CCM06451.1 - 0.028 14.5 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_8 PF13450.1 CCM06451.1 - 0.029 14.3 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 CCM06451.1 - 0.036 13.2 0.1 0.42 9.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 CCM06451.1 - 0.15 10.5 0.0 0.49 8.8 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lsm_interact PF05391.6 CCM06453.1 - 0.032 13.6 0.8 0.065 12.6 0.5 1.4 1 0 0 1 1 1 0 Lsm interaction motif F-box-like PF12937.2 CCM06454.1 - 0.011 15.4 0.3 0.023 14.4 0.2 1.5 1 0 0 1 1 1 0 F-box-like DUF3110 PF11360.3 CCM06457.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) p450 PF00067.17 CCM06458.1 - 2e-21 76.0 0.0 2.3e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.22 CCM06459.1 - 0.00042 19.7 0.4 0.0063 15.8 0.1 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like PF12937.2 CCM06460.1 - 7.5e-11 41.5 0.5 7.5e-11 41.5 0.3 3.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 CCM06460.1 - 9.9 5.9 12.6 2.6 7.7 2.7 3.9 3 1 0 3 3 3 0 F-box domain TPR_12 PF13424.1 CCM06462.1 - 0.01 15.7 0.1 0.07 13.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat P-II PF00543.17 CCM06462.1 - 0.031 14.7 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II TPR_11 PF13414.1 CCM06462.1 - 0.033 13.8 0.0 6.1 6.5 0.0 3.1 2 1 0 2 2 2 0 TPR repeat BTB PF00651.26 CCM06462.1 - 0.062 13.3 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain TPR_8 PF13181.1 CCM06462.1 - 0.12 12.1 0.0 24 4.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ndc1_Nup PF09531.5 CCM06463.1 - 0.45 8.8 3.0 0.56 8.5 2.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TSGP1 PF07771.6 CCM06463.1 - 9.5 6.1 7.6 2.3 8.1 0.6 2.2 1 1 1 2 2 2 0 Tick salivary peptide group 1 DUF2062 PF09835.4 CCM06464.1 - 0.041 13.4 0.8 0.086 12.4 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF2407_C PF13373.1 CCM06464.1 - 0.21 11.5 1.1 0.92 9.4 0.0 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain RTA1 PF04479.8 CCM06469.1 - 9.4e-39 133.2 8.4 1.9e-38 132.1 5.8 1.5 1 1 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.11 CCM06470.1 - 1.1e-44 152.5 46.9 1.4e-44 152.2 30.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCM06470.1 - 2.3e-15 55.8 12.9 3.6e-15 55.1 8.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) APH PF01636.18 CCM06471.1 - 0.0027 17.4 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CCM06471.1 - 0.0045 16.1 0.1 0.0077 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CCM06472.1 - 0.0016 17.6 0.1 0.0026 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCM06472.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 CCM06481.1 - 1.2e-58 198.3 0.0 3.3e-58 196.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06481.1 - 6.9e-29 100.6 0.1 3.2e-20 72.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCM06481.1 - 3.3e-05 22.9 0.7 0.0016 17.4 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 CCM06481.1 - 0.0046 16.7 0.2 0.048 13.3 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CCM06481.1 - 0.0094 15.0 0.0 0.024 13.6 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM06481.1 - 0.019 14.3 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.11 CCM06482.1 - 2.9e-13 49.2 32.5 5.4e-13 48.3 22.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 CCM06482.1 - 2.2e-10 40.2 6.8 6.4e-10 38.7 4.7 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 TB2_DP1_HVA22 PF03134.14 CCM06483.1 - 5.3e-27 93.3 3.7 9.5e-27 92.5 2.5 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TFIIS_C PF01096.13 CCM06483.1 - 1.8e-10 40.2 0.1 1.8e-10 40.2 0.1 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCM06483.1 - 1.5e-07 31.0 5.5 1.1e-06 28.2 2.2 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 CCM06483.1 - 0.0014 18.3 4.2 0.024 14.4 0.9 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.1 CCM06483.1 - 0.0094 15.1 8.6 1.1 8.5 0.0 3.2 3 0 0 3 3 3 2 zinc-ribbon domain UPF0547 PF10571.4 CCM06483.1 - 0.029 14.0 6.3 0.62 9.8 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1595 PF12760.2 CCM06483.1 - 0.054 13.3 2.8 1.2 8.9 0.0 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CCM06483.1 - 0.094 12.3 0.6 8.9 6.0 0.1 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.8 CCM06483.1 - 0.22 11.0 2.4 3.4 7.2 0.2 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DNA_ligase_ZBD PF03119.11 CCM06483.1 - 0.32 10.7 2.9 15 5.4 0.4 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_2 PF13240.1 CCM06483.1 - 0.33 10.4 11.3 1.7 8.2 2.5 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Mito_fiss_reg PF05308.6 CCM06483.1 - 0.45 9.8 6.2 0.74 9.1 4.2 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator Zn-ribbon_8 PF09723.5 CCM06483.1 - 0.61 10.0 6.1 17 5.4 0.1 3.0 2 1 1 3 3 3 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 CCM06483.1 - 2.8 7.3 8.5 9.5 5.6 0.1 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding zf-tcix PF14952.1 CCM06483.1 - 4.4 6.7 5.2 11 5.4 0.0 2.6 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding PhnA_Zn_Ribbon PF08274.7 CCM06483.1 - 8.2 6.3 8.9 16 5.3 0.1 3.0 2 1 1 3 3 3 0 PhnA Zinc-Ribbon Peptidase_M1 PF01433.15 CCM06484.1 - 7.1e-61 206.4 0.0 9.7e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CCM06484.1 - 2.3e-26 92.0 0.0 4.8e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CCM06484.1 - 1.8e-12 47.4 0.2 3.2e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily ArfGap PF01412.13 CCM06485.1 - 2.3e-42 143.4 0.2 3.4e-42 142.9 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1631 PF07793.6 CCM06485.1 - 2.6 6.0 7.3 3.5 5.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) L51_S25_CI-B8 PF05047.11 CCM06487.1 - 1.5e-08 34.2 0.1 2.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain YL1 PF05764.8 CCM06488.1 - 3.7e-22 79.1 13.1 4.9e-22 78.7 9.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 CCM06488.1 - 4.8e-12 45.2 0.0 9.9e-12 44.2 0.0 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain AAA PF00004.24 CCM06492.1 - 2.2e-40 137.8 0.0 9e-14 51.8 0.0 5.2 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 CCM06492.1 - 2.5e-38 131.4 0.0 9e-38 129.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCM06492.1 - 4.1e-29 101.8 20.7 1.2e-24 87.1 0.0 6.6 6 0 0 6 6 6 2 AAA domain AAA_19 PF13245.1 CCM06492.1 - 1.3e-21 76.0 2.6 2.5e-07 30.3 0.0 5.3 4 0 0 4 4 4 4 Part of AAA domain AAA_22 PF13401.1 CCM06492.1 - 5.8e-14 52.3 9.8 0.0025 17.9 0.0 8.0 5 3 0 5 5 5 2 AAA domain AAA_5 PF07728.9 CCM06492.1 - 2.5e-13 49.9 3.4 0.005 16.5 0.0 5.3 5 0 0 5 5 4 3 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 CCM06492.1 - 7.5e-13 48.5 0.4 0.017 14.6 0.0 5.3 5 0 0 5 5 5 3 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 CCM06492.1 - 2.2e-12 46.5 0.7 0.038 13.1 0.0 4.9 5 0 0 5 5 5 4 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CCM06492.1 - 3.8e-12 47.0 16.1 0.027 15.2 0.0 6.5 7 0 0 7 7 5 4 AAA domain IstB_IS21 PF01695.12 CCM06492.1 - 7.8e-10 38.4 0.1 0.079 12.3 0.0 4.7 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_30 PF13604.1 CCM06492.1 - 1.6e-09 37.6 22.3 0.0015 18.1 0.0 6.9 7 1 0 7 7 5 4 AAA domain AAA_18 PF13238.1 CCM06492.1 - 4.4e-09 36.7 6.2 0.28 11.5 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA_24 PF13479.1 CCM06492.1 - 3.4e-07 30.0 2.8 0.51 9.8 0.0 4.7 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.17 CCM06492.1 - 5.7e-07 29.6 0.1 3.5 7.8 0.0 4.5 4 0 0 4 4 4 1 RNA helicase Sigma54_activat PF00158.21 CCM06492.1 - 8.3e-07 28.6 0.5 1.5 8.2 0.0 5.3 5 1 0 5 5 5 1 Sigma-54 interaction domain AAA_16 PF13191.1 CCM06492.1 - 1.1e-06 28.8 24.6 0.11 12.5 0.0 6.7 6 1 0 6 6 5 3 AAA ATPase domain AAA_14 PF13173.1 CCM06492.1 - 1.2e-06 28.4 0.0 0.42 10.5 0.0 4.3 4 0 0 4 4 4 2 AAA domain DUF2075 PF09848.4 CCM06492.1 - 3.7e-06 26.1 4.7 0.059 12.3 0.0 5.8 5 1 0 5 5 5 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CCM06492.1 - 1.1e-05 25.3 0.8 0.019 14.8 0.0 4.5 5 0 0 5 5 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CCM06492.1 - 2.1e-05 23.8 0.6 1.9 7.6 0.0 4.6 4 0 0 4 4 4 2 PhoH-like protein AAA_33 PF13671.1 CCM06492.1 - 0.0003 20.6 21.5 0.4 10.5 0.1 6.0 6 0 0 6 6 5 3 AAA domain KTI12 PF08433.5 CCM06492.1 - 0.00036 19.8 0.9 6.1 5.9 0.0 4.0 4 0 0 4 4 4 0 Chromatin associated protein KTI12 NACHT PF05729.7 CCM06492.1 - 0.00088 18.9 1.7 5.3 6.6 0.0 4.6 4 0 0 4 4 4 0 NACHT domain SRP54 PF00448.17 CCM06492.1 - 0.0014 18.0 1.3 0.75 9.2 0.0 3.9 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain 6PF2K PF01591.13 CCM06492.1 - 0.0016 17.5 0.1 0.069 12.2 0.0 2.8 3 0 0 3 3 3 1 6-phosphofructo-2-kinase KaiC PF06745.8 CCM06492.1 - 0.011 14.8 7.3 1.6 7.8 0.0 4.6 5 0 0 5 5 4 0 KaiC AAA_3 PF07726.6 CCM06492.1 - 0.011 15.3 0.3 27 4.3 0.0 4.2 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CCM06492.1 - 0.013 15.1 3.1 5.3 6.7 0.0 3.9 4 0 0 4 4 3 0 NTPase VirE PF05272.6 CCM06492.1 - 0.021 14.2 0.0 0.076 12.4 0.0 1.9 2 0 0 2 2 1 0 Virulence-associated protein E Aminotran_1_2 PF00155.16 CCM06492.1 - 0.059 12.3 0.0 0.26 10.1 0.0 2.1 3 0 0 3 3 3 0 Aminotransferase class I and II G-alpha PF00503.15 CCM06492.1 - 0.066 11.8 0.1 0.066 11.8 0.0 4.1 4 1 0 4 4 2 0 G-protein alpha subunit NB-ARC PF00931.17 CCM06492.1 - 0.073 11.9 0.5 3.9 6.2 0.0 3.3 3 0 0 3 3 3 0 NB-ARC domain AAA_28 PF13521.1 CCM06492.1 - 0.13 12.2 0.0 0.13 12.2 0.0 6.1 6 1 0 6 6 4 0 AAA domain AAA_25 PF13481.1 CCM06492.1 - 0.13 11.6 12.6 5.9 6.2 0.0 4.8 5 0 0 5 5 4 0 AAA domain MobB PF03205.9 CCM06492.1 - 0.14 11.8 0.5 30 4.3 0.0 3.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ADK PF00406.17 CCM06492.1 - 0.32 10.8 2.6 45 3.8 0.0 4.0 4 0 0 4 4 3 0 Adenylate kinase ABC_tran PF00005.22 CCM06492.1 - 6.7 7.0 10.8 24 5.2 0.0 5.1 6 0 0 6 6 4 0 ABC transporter Sugar_tr PF00083.19 CCM06493.1 - 5.6e-90 302.0 20.6 8.8e-81 271.7 7.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCM06493.1 - 8.4e-18 64.1 20.5 8.4e-18 64.1 14.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCM06493.1 - 3e-05 22.4 2.1 3e-05 22.4 1.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 CCM06493.1 - 0.0007 18.1 1.5 0.0007 18.1 1.0 3.2 3 1 1 4 4 4 2 MFS/sugar transport protein Ecl1 PF12855.2 CCM06495.1 - 0.00017 20.7 0.2 0.0075 15.5 0.1 2.4 2 0 0 2 2 2 2 Life-span regulatory factor DUF4131 PF13567.1 CCM06496.1 - 0.5 9.7 5.0 0.86 8.9 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PRA1 PF03208.14 CCM06496.1 - 8.4 5.7 10.5 13 5.0 7.3 1.3 1 0 0 1 1 1 0 PRA1 family protein DUF972 PF06156.8 CCM06497.1 - 0.16 12.3 0.1 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CSTF_C PF14304.1 CCM06497.1 - 0.26 10.5 0.1 0.26 10.5 0.1 1.9 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal ETX_MTX2 PF03318.8 CCM06498.1 - 1.3e-11 44.4 1.6 2.2e-11 43.7 1.1 1.4 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.15 CCM06498.1 - 1.2e-05 24.4 0.4 1.6e-05 24.0 0.3 1.1 1 0 0 1 1 1 1 Aerolysin toxin Fascin PF06268.8 CCM06498.1 - 7.8e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Fascin domain Binary_toxB PF03495.9 CCM06498.1 - 0.0058 15.3 4.6 0.039 12.5 3.2 1.9 1 1 0 1 1 1 1 Clostridial binary toxin B/anthrax toxin PA ETX_MTX2 PF03318.8 CCM06500.1 - 5.7e-09 35.8 4.1 9.2e-09 35.1 2.8 1.3 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Fascin PF06268.8 CCM06500.1 - 3.2e-05 23.9 0.0 6.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Fascin domain Aerolysin PF01117.15 CCM06500.1 - 0.012 14.5 1.6 0.019 13.9 1.1 1.2 1 0 0 1 1 1 0 Aerolysin toxin PKD PF00801.15 CCM06500.1 - 0.021 14.5 4.0 0.26 11.0 1.9 3.1 2 1 0 2 2 2 0 PKD domain Binary_toxB PF03495.9 CCM06500.1 - 0.1 11.2 4.1 2.5 6.6 0.1 2.1 1 1 1 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Aldedh PF00171.17 CCM06502.1 - 1.5e-173 577.3 0.1 1.7e-173 577.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCM06502.1 - 0.031 12.9 0.0 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 CCM06502.1 - 0.032 13.4 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF1275 PF06912.6 CCM06503.1 - 4.7e-20 71.6 15.3 5.5e-20 71.4 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Citrate_synt PF00285.16 CCM06504.1 - 2.9e-17 62.4 0.0 3e-15 55.8 0.0 2.6 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 CCM06504.1 - 1.6e-15 57.0 0.0 3.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 CCM06504.1 - 7.7e-13 48.7 0.0 2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 CCM06504.1 - 2.4e-08 33.6 0.0 4.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CCM06504.1 - 8.3e-05 22.2 0.0 0.00029 20.4 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain zf-Di19 PF05605.7 CCM06506.1 - 0.052 13.6 6.2 1.6 8.9 0.3 3.0 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding p47_phox_C PF08944.6 CCM06506.1 - 0.057 13.6 0.3 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Zn_Tnp_IS1 PF03811.8 CCM06506.1 - 0.065 12.7 5.9 0.86 9.1 0.2 3.8 3 0 0 3 3 3 0 InsA N-terminal domain Thioredoxin PF00085.15 CCM06507.1 - 3e-25 87.8 0.0 3.7e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCM06507.1 - 6.6e-07 29.5 0.1 5e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCM06507.1 - 1.1e-06 28.6 0.0 1.2e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CCM06507.1 - 5.6e-05 22.7 0.0 7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CCM06507.1 - 0.00024 20.7 0.0 0.0012 18.5 0.0 1.8 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CCM06507.1 - 0.00076 19.0 0.1 0.036 13.6 0.0 2.1 1 1 1 2 2 2 1 Redoxin HyaE PF07449.6 CCM06507.1 - 0.089 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Asp_protease_2 PF13650.1 CCM06509.1 - 0.042 14.3 0.0 0.097 13.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Pkinase PF00069.20 CCM06511.1 - 2.2e-20 72.8 0.0 3.6e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06511.1 - 9.4e-05 21.6 0.2 0.0027 16.8 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CCM06511.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM06511.1 - 0.062 12.6 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CCM06511.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family EHN PF06441.7 CCM06512.1 - 4.5e-33 113.5 0.2 3.3e-32 110.7 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CCM06512.1 - 1.7e-12 47.7 4.1 3.7e-12 46.5 2.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM06512.1 - 1e-11 44.8 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM06512.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family ABC_tran PF00005.22 CCM06514.1 - 8.2e-28 97.4 0.1 1.7e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCM06514.1 - 6e-05 22.3 0.8 0.025 13.7 0.1 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCM06514.1 - 0.0014 18.6 0.4 0.0051 16.8 0.3 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CCM06514.1 - 0.0027 17.7 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain Fungal_trans PF04082.13 CCM06514.1 - 0.0033 16.3 0.2 0.0073 15.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_25 PF13481.1 CCM06514.1 - 0.004 16.5 0.1 0.025 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CCM06514.1 - 0.019 14.8 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_29 PF13555.1 CCM06514.1 - 0.028 13.9 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCM06514.1 - 0.036 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CCM06514.1 - 0.053 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DctQ PF04290.7 CCM06514.1 - 0.17 11.6 5.5 3.5 7.4 0.9 2.5 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component AAA_10 PF12846.2 CCM06514.1 - 0.18 11.2 1.5 2 7.7 0.1 2.2 1 1 0 2 2 2 0 AAA-like domain WD40 PF00400.27 CCM06516.1 - 0.015 15.1 0.4 0.36 10.7 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Epimerase PF01370.16 CCM06517.1 - 2.7e-21 76.0 0.0 3.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCM06517.1 - 2.7e-09 36.1 0.0 3.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CCM06517.1 - 7.3e-07 28.3 0.0 1.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CCM06517.1 - 5.3e-06 26.5 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCM06517.1 - 2.1e-05 23.5 0.0 0.0071 15.2 0.1 2.3 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 CCM06517.1 - 2.4e-05 23.3 0.0 9.6e-05 21.4 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 CCM06517.1 - 0.00011 22.1 0.0 0.00027 20.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM06517.1 - 0.0022 17.6 0.1 0.041 13.5 0.1 2.2 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.13 CCM06519.1 - 5.4e-16 58.2 1.0 9.3e-16 57.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCM06519.1 - 5.7e-06 26.1 10.1 1e-05 25.2 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 CCM06520.1 - 4.3e-32 111.0 0.0 2e-30 105.5 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme RVT_1 PF00078.22 CCM06525.1 - 4e-19 68.8 0.0 1.1e-18 67.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF221 PF02714.10 CCM06528.1 - 4.2e-102 341.3 22.8 6.7e-102 340.6 15.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCM06528.1 - 1.1e-33 115.9 1.8 1.1e-33 115.9 1.2 2.9 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CCM06528.1 - 9.7e-14 51.6 0.0 2.2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 CCM06528.1 - 0.1 12.6 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 CCM06529.1 - 5.6e-42 142.4 0.0 7.1e-42 142.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CCM06529.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 UEV domain GATA PF00320.22 CCM06531.1 - 3.4e-09 35.8 6.2 6.6e-09 34.9 4.3 1.5 1 0 0 1 1 1 1 GATA zinc finger PHD_3 PF13922.1 CCM06531.1 - 2.4 8.4 4.6 18 5.6 2.0 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Thiolase_N PF00108.18 CCM06532.1 - 5e-82 274.8 4.5 9.1e-82 273.9 1.3 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCM06532.1 - 6.5e-47 157.9 0.3 1.4e-46 156.8 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCM06532.1 - 0.0068 15.9 4.9 0.0098 15.3 1.1 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CCM06532.1 - 0.011 15.3 1.3 3.2 7.4 0.1 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abi PF02517.11 CCM06533.1 - 1.7 8.7 10.8 0.24 11.5 2.1 2.4 2 0 0 2 2 2 0 CAAX protease self-immunity YqhR PF11085.3 CCM06533.1 - 9.1 5.7 13.1 1.4 8.3 2.9 2.1 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF2976 PF11190.3 CCM06534.1 - 3.6 7.1 6.0 0.87 9.1 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) Como_LCP PF02247.11 CCM06535.1 - 0.031 12.6 0.1 0.065 11.6 0.1 1.4 1 0 0 1 1 1 0 Large coat protein Pyr_redox_3 PF13738.1 CCM06537.1 - 2e-25 90.0 0.1 9.8e-25 87.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCM06537.1 - 2.6e-20 72.1 0.5 9.3e-17 60.4 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CCM06537.1 - 2.5e-13 50.3 0.0 1.2e-11 44.9 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCM06537.1 - 9.6e-13 47.7 0.2 2.6e-09 36.4 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 CCM06537.1 - 2.3e-09 37.5 1.2 0.003 17.9 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCM06537.1 - 7e-07 28.4 4.8 0.025 13.4 0.4 3.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCM06537.1 - 4.9e-06 26.4 0.1 0.51 10.1 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CCM06537.1 - 6.2e-06 26.1 0.2 0.0001 22.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCM06537.1 - 1.9e-05 23.8 0.7 0.00018 20.6 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 CCM06537.1 - 0.0023 16.4 0.2 0.082 11.3 0.1 2.8 3 0 0 3 3 3 1 HI0933-like protein 2-Hacid_dh_C PF02826.14 CCM06537.1 - 0.0023 17.1 0.0 0.026 13.6 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 CCM06537.1 - 0.0036 16.4 0.1 0.083 11.9 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 CCM06537.1 - 0.0047 15.8 0.7 0.039 12.8 0.5 2.4 3 1 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.13 CCM06537.1 - 0.005 16.5 1.0 0.15 11.7 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 CCM06537.1 - 0.013 14.8 0.3 1.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 CCM06537.1 - 0.032 13.1 0.1 0.11 11.3 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein DUF2914 PF11141.3 CCM06537.1 - 0.032 13.7 1.2 0.44 10.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) Shikimate_DH PF01488.15 CCM06537.1 - 0.15 12.1 0.1 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 CCM06538.1 - 5.9e-23 81.9 0.0 7.3e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM06538.1 - 7.4e-10 38.7 0.0 7.4e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCM06538.1 - 3.9e-06 26.6 0.0 6.6e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCM06538.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF3357 PF11837.3 CCM06540.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ERGIC_N PF13850.1 CCM06540.1 - 0.099 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Methyltrans_Mon PF14314.1 CCM06540.1 - 0.12 10.1 0.0 0.15 9.9 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase DUF3328 PF11807.3 CCM06541.1 - 1.2e-16 61.1 0.7 1.8e-16 60.4 0.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) WD40 PF00400.27 CCM06543.1 - 1.6e-168 541.2 78.6 5.7e-13 48.1 0.1 15.9 16 0 0 16 16 16 14 WD domain, G-beta repeat PQQ_3 PF13570.1 CCM06543.1 - 1.1e-28 98.6 7.2 0.072 13.3 0.0 14.1 12 2 2 14 14 14 4 PQQ-like domain Nup160 PF11715.3 CCM06543.1 - 1.1e-16 60.0 25.8 0.33 9.0 0.2 12.1 1 1 10 12 12 12 8 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCM06543.1 - 1.2e-13 50.6 40.0 0.032 13.0 2.8 12.0 1 1 5 7 7 7 5 Nup133 N terminal like Cytochrom_D1 PF02239.11 CCM06543.1 - 6.8e-12 44.3 17.1 0.0055 15.0 0.2 6.1 3 2 3 6 6 6 6 Cytochrome D1 heme domain PQQ_2 PF13360.1 CCM06543.1 - 3.5e-09 36.4 13.7 0.00013 21.5 5.2 4.8 1 1 3 4 4 4 4 PQQ-like domain Peptidase_S9_N PF02897.10 CCM06543.1 - 6.2e-08 31.6 4.3 0.12 10.9 0.1 7.9 4 2 4 8 8 8 1 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_16 PF13191.1 CCM06543.1 - 9.4e-06 25.7 0.2 2.4e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 CCM06543.1 - 0.00012 21.7 0.0 0.00033 20.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 CCM06543.1 - 0.00093 18.1 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 CCM06543.1 - 0.0041 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain FeThRed_A PF02941.10 CCM06543.1 - 0.0051 16.7 11.2 54 3.8 0.0 8.6 8 2 2 10 10 10 0 Ferredoxin thioredoxin reductase variable alpha chain bPH_4 PF06713.6 CCM06543.1 - 0.0096 15.7 0.0 2.4 8.0 0.0 4.4 5 0 0 5 5 4 1 Bacterial PH domain AAA_22 PF13401.1 CCM06543.1 - 0.011 15.8 0.0 0.037 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCM06543.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 CCM06543.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SLH PF00395.15 CCM06543.1 - 0.1 12.3 0.0 40 4.0 0.0 4.4 5 0 0 5 5 5 0 S-layer homology domain AAA PF00004.24 CCM06543.1 - 0.16 12.1 0.0 0.69 10.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) F-box PF00646.28 CCM06544.1 - 0.3 10.7 3.6 0.65 9.7 1.2 2.5 2 1 0 2 2 2 0 F-box domain FHA PF00498.21 CCM06547.1 - 6.5e-15 55.0 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CCM06547.1 - 5e-09 35.8 10.1 9e-09 35.0 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCM06547.1 - 2.2e-05 24.4 6.6 4.6e-05 23.4 4.6 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCM06547.1 - 6e-05 22.6 9.8 0.0001 21.8 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCM06547.1 - 0.00024 20.8 2.0 0.00046 19.9 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 CCM06547.1 - 0.0064 16.1 4.6 0.013 15.1 3.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_4 PF15227.1 CCM06547.1 - 0.0083 15.9 1.5 0.022 14.6 1.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCM06547.1 - 0.012 15.3 8.5 0.021 14.5 5.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCM06547.1 - 0.023 14.6 11.0 0.043 13.8 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCM06547.1 - 0.025 14.2 6.5 0.047 13.3 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCM06547.1 - 3.9 7.2 6.7 11 5.8 4.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Ras PF00071.17 CCM06548.1 - 3.8e-34 117.4 0.2 4.5e-34 117.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCM06548.1 - 6.8e-23 81.4 0.1 5.2e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 CCM06548.1 - 2.7e-08 33.2 0.2 3.3e-08 32.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CCM06548.1 - 3.9e-08 32.7 0.1 4.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCM06548.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 CCM06548.1 - 0.018 13.7 0.8 0.061 11.9 0.0 2.1 1 1 2 3 3 3 0 G-protein alpha subunit DLIC PF05783.6 CCM06548.1 - 0.12 11.0 0.7 7.9 5.0 0.0 2.0 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) polyprenyl_synt PF00348.12 CCM06549.1 - 8.2e-22 77.2 0.0 9.3e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase OPT PF03169.10 CCM06550.1 - 7.2e-80 269.1 17.9 9e-80 268.8 12.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Shisa PF13908.1 CCM06551.1 - 0.0068 16.6 1.5 0.0068 16.6 1.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Choline_transpo PF04515.7 CCM06551.1 - 0.0077 15.0 0.2 0.0083 14.8 0.1 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter EphA2_TM PF14575.1 CCM06551.1 - 0.022 15.1 1.7 0.039 14.3 1.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.6 CCM06551.1 - 0.037 13.3 7.9 0.062 12.6 5.5 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Herpes_gE PF02480.11 CCM06551.1 - 0.27 9.4 1.0 0.29 9.3 0.7 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ODV-E18 PF10717.4 CCM06551.1 - 0.95 8.9 2.8 1.7 8.1 2.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RhodobacterPufX PF11511.3 CCM06551.1 - 1.2 8.5 10.1 2 7.8 7.0 1.3 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Corona_S2 PF01601.11 CCM06551.1 - 1.8 6.5 3.9 2.4 6.1 2.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF912 PF06024.7 CCM06551.1 - 3.1 7.8 5.6 4.5 7.3 3.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) COX5A PF02284.11 CCM06553.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Mucin PF01456.12 CCM06554.1 - 0.038 13.7 28.6 0.084 12.6 19.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.1 CCM06554.1 - 0.51 10.0 8.0 0.86 9.3 5.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family Sporozoite_P67 PF05642.6 CCM06554.1 - 0.58 7.9 6.2 0.73 7.6 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen rve PF00665.21 CCM06557.1 - 6.3e-09 35.9 0.0 7.3e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CCM06558.1 - 2e-10 40.3 0.1 9.9e-10 38.1 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aldedh PF00171.17 CCM06559.1 - 2.7e-110 368.8 0.2 3.2e-110 368.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_3_C PF01915.17 CCM06563.1 - 3e-53 180.6 0.0 4.2e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCM06563.1 - 1.3e-18 66.6 0.2 2.6e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 CCM06563.1 - 5.6e-18 64.9 0.0 9.4e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain polyprenyl_synt PF00348.12 CCM06564.1 - 0.0041 16.0 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Peptidase_M91 PF14891.1 CCM06567.1 - 0.037 14.0 0.3 0.039 14.0 0.2 1.1 1 0 0 1 1 1 0 Effector protein MutL PF13941.1 CCM06567.1 - 0.037 12.3 0.4 0.043 12.1 0.3 1.0 1 0 0 1 1 1 0 MutL protein DUF1876 PF08962.6 CCM06567.1 - 0.12 12.1 0.5 0.16 11.8 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1876) DUF1675 PF07897.6 CCM06567.1 - 0.19 11.5 1.3 0.22 11.3 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) WD40 PF00400.27 CCM06569.1 - 1.2e-17 62.9 27.8 0.00069 19.4 0.0 10.5 10 0 0 10 10 10 5 WD domain, G-beta repeat NACHT PF05729.7 CCM06569.1 - 1.7e-07 31.0 0.0 3.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CCM06569.1 - 8.5e-06 25.8 0.1 2.9e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CCM06569.1 - 0.023 14.9 0.0 0.11 12.6 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 CCM06569.1 - 0.035 13.7 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase SDA1 PF05285.7 CCM06569.1 - 1.8 7.7 16.7 3.3 6.8 11.6 1.3 1 0 0 1 1 1 0 SDA1 Ribonuc_2-5A PF06479.7 CCM06570.1 - 2.7e-43 146.8 0.6 4.5e-43 146.1 0.4 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 CCM06570.1 - 2.3e-39 135.1 0.0 3.2e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06570.1 - 3.6e-18 65.5 0.0 1.3e-17 63.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 CCM06570.1 - 0.004 16.6 0.0 0.012 15.1 0.0 1.9 1 0 0 1 1 1 1 PQQ enzyme repeat PQQ_2 PF13360.1 CCM06570.1 - 0.015 14.7 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain Kdo PF06293.9 CCM06570.1 - 0.054 12.5 0.1 0.092 11.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family His_biosynth PF00977.16 CCM06572.1 - 3.4e-06 26.5 0.0 5.4e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Histidine biosynthesis protein DUF1954 PF09199.5 CCM06573.1 - 0.15 12.2 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1954) SSP160 PF06933.6 CCM06574.1 - 2.1 6.2 9.0 2.7 5.8 6.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.11 CCM06575.1 - 6.7e-13 48.0 10.3 1.7e-12 46.7 6.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 CCM06575.1 - 0.049 12.8 0.1 0.049 12.8 0.0 2.9 2 1 1 3 3 3 0 Nodulin-like DUF2244 PF10003.4 CCM06575.1 - 0.19 11.0 2.6 0.22 10.9 0.0 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Peptidase_S10 PF00450.17 CCM06576.1 - 5.4e-61 206.9 0.0 7.4e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase YiaAB PF05360.9 CCM06576.1 - 0.24 10.9 0.9 10 5.7 0.1 2.6 3 0 0 3 3 3 0 yiaA/B two helix domain Peptidase_S10 PF00450.17 CCM06577.1 - 2.4e-51 175.1 4.1 3.3e-51 174.7 2.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase BTB PF00651.26 CCM06578.1 - 0.00011 22.1 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Dimer_Tnp_hAT PF05699.9 CCM06579.1 - 0.0069 15.9 0.1 0.0078 15.8 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Furin-like PF00757.15 CCM06581.1 - 0.028 14.0 3.2 0.052 13.2 2.2 1.4 1 0 0 1 1 1 0 Furin-like cysteine rich region UBN2_3 PF14244.1 CCM06582.1 - 4.8e-09 35.9 0.1 5.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CCM06582.1 - 0.016 14.5 0.3 0.033 13.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) RVT_2 PF07727.9 CCM06583.1 - 1.7e-89 299.0 0.0 2.6e-89 298.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCM06583.1 - 1.1e-27 96.5 0.0 4.3e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CCM06583.1 - 6.7e-12 44.8 0.0 1.9e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CCM06583.1 - 7.7e-05 22.1 0.0 0.0002 20.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain eIF3g PF12353.3 CCM06583.1 - 0.0026 17.6 0.9 0.0052 16.6 0.6 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G UBN2 PF14223.1 CCM06583.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CCM06583.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF601 PF04642.7 CCM06583.1 - 0.17 11.2 8.0 0.026 13.9 2.8 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF601 F-box-like PF12937.2 CCM06585.1 - 0.00074 19.1 0.1 0.0029 17.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCM06585.1 - 0.0055 16.3 0.2 0.035 13.7 0.0 2.5 2 0 0 2 2 2 1 F-box domain DLIC PF05783.6 CCM06586.1 - 0.05 12.2 2.5 0.062 11.9 1.7 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF1115 PF06544.7 CCM06586.1 - 0.11 12.2 0.8 0.22 11.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) CT47 PF15623.1 CCM06586.1 - 0.19 11.4 14.4 0.28 10.8 10.0 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Cupin_2 PF07883.6 CCM06587.1 - 8.9e-30 102.0 0.5 3.8e-14 51.9 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CCM06587.1 - 2.2e-28 98.4 0.1 5.9e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 CCM06587.1 - 4.6e-11 41.9 0.1 0.00012 21.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 CCM06587.1 - 1.7e-07 31.0 0.3 4.8e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 CCM06587.1 - 4.8e-06 26.2 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 CCM06587.1 - 0.003 16.9 0.0 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.2 CCM06587.1 - 0.0034 17.0 0.0 0.31 10.6 0.0 2.3 1 1 1 2 2 2 1 Cupin Pirin_C PF05726.8 CCM06587.1 - 0.0079 16.2 0.0 3.9 7.5 0.0 2.3 2 0 0 2 2 2 2 Pirin C-terminal cupin domain Cupin_4 PF08007.7 CCM06587.1 - 0.016 14.5 0.1 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Cupin superfamily protein GPI PF06560.6 CCM06587.1 - 0.034 13.1 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) ARD PF03079.9 CCM06587.1 - 0.06 13.2 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 ARD/ARD' family Cupin_8 PF13621.1 CCM06587.1 - 0.11 11.9 0.0 0.9 8.9 0.0 2.4 1 1 0 1 1 1 0 Cupin-like domain cNMP_binding PF00027.24 CCM06587.1 - 0.18 11.6 0.2 1.3 8.8 0.0 2.3 3 0 0 3 3 2 0 Cyclic nucleotide-binding domain Meth_synt_2 PF01717.13 CCM06588.1 - 3.6e-19 68.9 0.0 4.8e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCM06588.1 - 1.7e-07 30.8 0.0 0.035 13.3 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain ApoO PF09769.4 CCM06590.1 - 3.1e-31 108.2 0.2 7.5e-31 106.9 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O GST_N PF02798.15 CCM06590.1 - 2.3e-15 56.5 0.0 4.5e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCM06590.1 - 3.7e-14 52.6 0.0 8.6e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCM06590.1 - 1e-11 44.6 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCM06590.1 - 4.8e-09 36.0 0.0 9.4e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCM06590.1 - 5e-07 29.5 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-C2H2 PF00096.21 CCM06591.1 - 3e-10 39.8 15.9 0.0033 17.6 2.0 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCM06591.1 - 1.9e-07 30.9 8.4 0.0001 22.3 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCM06591.1 - 2.5e-07 30.5 15.4 0.012 15.9 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCM06591.1 - 0.085 13.0 3.4 24 5.2 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 CCM06591.1 - 0.2 11.4 2.9 0.44 10.3 2.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SprT-like PF10263.4 CCM06591.1 - 0.29 10.8 4.3 0.63 9.6 2.3 1.8 1 1 1 2 2 2 0 SprT-like family Mut7-C PF01927.11 CCM06591.1 - 0.73 9.8 4.0 0.56 10.1 0.7 2.2 2 0 0 2 2 2 0 Mut7-C RNAse domain C1_4 PF07975.7 CCM06591.1 - 1.2 9.2 3.5 4.6 7.3 2.4 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 CCM06591.1 - 2.1 8.1 6.2 6.2 6.7 0.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_6 PF13912.1 CCM06591.1 - 4.6 7.2 8.4 18 5.4 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Pyr_redox_dim PF02852.17 CCM06592.1 - 5.2e-43 145.5 2.2 2.7e-42 143.2 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CCM06592.1 - 1.8e-41 142.2 1.7 2.8e-41 141.6 0.4 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCM06592.1 - 7.7e-23 80.6 6.3 5e-19 68.4 1.3 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM06592.1 - 5.9e-12 46.0 0.1 4.6e-07 30.0 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCM06592.1 - 8.3e-10 38.0 6.4 7.5e-09 34.9 0.8 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CCM06592.1 - 1.1e-09 38.2 2.0 5.5e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CCM06592.1 - 3.1e-09 36.4 12.6 4e-09 36.0 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCM06592.1 - 3.4e-07 29.4 1.0 3.4e-07 29.4 0.7 4.1 3 1 0 4 4 4 1 FAD binding domain DAO PF01266.19 CCM06592.1 - 6.5e-07 28.5 17.3 0.027 13.4 0.2 4.2 2 2 2 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.9 CCM06592.1 - 1e-06 27.5 10.8 0.00061 18.3 0.0 4.1 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 CCM06592.1 - 1.3e-06 27.6 2.4 0.002 17.2 0.0 2.4 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.1 CCM06592.1 - 1e-05 24.6 1.5 0.027 13.3 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 CCM06592.1 - 4.6e-05 22.6 10.1 0.089 11.8 0.1 3.4 3 0 0 3 3 3 3 FAD binding domain AlaDh_PNT_C PF01262.16 CCM06592.1 - 7.4e-05 22.3 1.1 0.038 13.5 0.1 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DUF4479 PF14794.1 CCM06592.1 - 0.09 12.3 1.2 6.2 6.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4479) THF_DHG_CYH_C PF02882.14 CCM06592.1 - 0.1 11.6 3.9 0.053 12.5 0.4 2.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.7 CCM06592.1 - 0.28 10.0 7.4 0.77 8.5 0.1 3.4 3 1 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CCM06592.1 - 0.47 10.0 4.0 0.71 9.5 0.8 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GST_N PF02798.15 CCM06593.1 - 1.9e-17 63.1 0.0 1.6e-16 60.2 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM06593.1 - 4.4e-14 52.2 0.0 8.9e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCM06593.1 - 2.2e-13 50.1 0.0 3.7e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCM06593.1 - 2.6e-12 46.5 0.1 4.4e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCM06593.1 - 6.1e-07 29.2 0.4 1e-06 28.5 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCM06593.1 - 0.00013 22.3 0.1 0.00021 21.7 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Atg8 PF02991.11 CCM06593.1 - 0.063 13.2 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like HHH PF00633.18 CCM06598.1 - 0.11 12.2 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif Nitroreductase PF00881.19 CCM06599.1 - 0.13 12.1 0.3 0.21 11.4 0.2 1.2 1 0 0 1 1 1 0 Nitroreductase family ETF PF01012.16 CCM06600.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain FAD_binding_3 PF01494.14 CCM06603.1 - 5.7e-09 35.4 0.0 1.3e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCM06603.1 - 5.7e-08 32.0 2.8 8.8e-08 31.4 1.4 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCM06603.1 - 9.9e-08 31.2 0.1 5e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CCM06603.1 - 1.2e-07 31.6 0.6 4e-07 29.9 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCM06603.1 - 3.4e-06 27.3 1.7 0.0046 17.3 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCM06603.1 - 2.6e-05 24.3 0.2 6.2e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCM06603.1 - 4.9e-05 21.9 0.9 0.004 15.6 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 CCM06603.1 - 0.00024 20.3 1.4 0.00048 19.3 0.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCM06603.1 - 0.00033 20.5 0.3 0.0015 18.4 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCM06603.1 - 0.00039 19.5 0.1 0.0007 18.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 CCM06603.1 - 0.00041 19.3 0.8 0.15 10.9 0.2 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.17 CCM06603.1 - 0.0077 15.1 0.1 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 CCM06603.1 - 0.016 14.3 0.2 0.1 11.6 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 CCM06603.1 - 0.018 13.6 1.9 0.033 12.8 0.5 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ThuA PF06283.6 CCM06604.1 - 1.5e-54 184.9 0.0 1.8e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF544 PF04424.8 CCM06605.1 - 3.5e-16 59.1 0.0 5.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) LRR_4 PF12799.2 CCM06606.1 - 2.1e-05 24.0 0.1 0.24 11.0 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CCM06606.1 - 0.00067 19.4 0.4 0.48 10.6 0.0 3.6 3 1 1 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 CCM06606.1 - 0.11 12.3 0.8 0.45 10.3 0.2 2.2 2 0 0 2 2 2 0 Leucine rich repeat MFS_1 PF07690.11 CCM06609.1 - 7.6e-18 64.3 36.6 8.9e-16 57.5 11.4 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCM06609.1 - 0.21 10.0 19.5 0.0055 15.3 8.3 1.9 2 0 0 2 2 2 0 Sugar (and other) transporter Pkinase PF00069.20 CCM06612.1 - 9.6e-07 28.2 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain p450 PF00067.17 CCM06613.1 - 4.7e-77 259.4 0.0 5.3e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nanovirus_coat PF04660.7 CCM06613.1 - 0.13 11.9 0.0 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 Nanovirus coat protein ICMT PF04140.9 CCM06614.1 - 7.4e-11 42.1 0.0 1.8e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCM06614.1 - 7.5e-10 38.8 0.1 2.8e-09 37.0 0.0 1.9 1 1 1 2 2 2 1 Phospholipid methyltransferase adh_short PF00106.20 CCM06616.1 - 0.026 14.4 1.2 3 7.7 0.5 2.2 1 1 1 2 2 2 0 short chain dehydrogenase Rib_5-P_isom_A PF06026.9 CCM06617.1 - 5.5e-56 188.6 0.0 6.9e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF3612 PF12268.3 CCM06617.1 - 0.093 12.5 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Tbf5 PF06331.7 CCM06618.1 - 3.1e-13 49.2 0.9 3.8e-12 45.8 0.4 2.0 2 0 0 2 2 2 1 Transcription factor TFIIH complex subunit Tfb5 MFS_1 PF07690.11 CCM06621.1 - 2.3e-46 158.1 35.3 1.1e-30 106.5 10.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 CCM06621.1 - 0.00038 19.0 24.4 0.016 13.7 5.0 2.3 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like DUF3487 PF11990.3 CCM06621.1 - 0.99 8.8 0.0 0.99 8.8 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3487) MFS_1_like PF12832.2 CCM06621.1 - 2.9 7.7 9.0 0.92 9.3 0.1 3.9 5 0 0 5 5 5 0 MFS_1 like family UbiA PF01040.13 CCM06623.1 - 1.2e-29 103.3 12.7 1.6e-29 102.9 8.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Peroxin-13_N PF04088.8 CCM06625.1 - 3.9e-41 140.6 0.0 6.3e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 CCM06625.1 - 2.7e-10 39.4 1.6 0.00074 18.8 1.4 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CCM06625.1 - 3.1e-09 36.1 0.0 4.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CCM06625.1 - 1.3e-07 31.0 0.9 2.8e-07 29.9 0.6 1.6 1 1 0 1 1 1 1 Variant SH3 domain Gln-synt_C PF00120.19 CCM06626.1 - 3.4e-50 170.6 0.0 4.4e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Pmp3 PF01679.12 CCM06627.1 - 3.7e-22 77.7 8.3 4.8e-22 77.4 5.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.6 CCM06627.1 - 0.073 13.1 0.6 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) PrgI PF12666.2 CCM06627.1 - 0.17 12.0 1.0 0.24 11.5 0.7 1.2 1 0 0 1 1 1 0 PrgI family protein Pkinase PF00069.20 CCM06628.1 - 6.9e-05 22.1 0.0 9.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCM06628.1 - 0.00037 20.3 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCM06628.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SDA1 PF05285.7 CCM06628.1 - 0.48 9.6 8.4 0.62 9.2 5.8 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 CCM06628.1 - 1.7 7.0 10.6 2.1 6.6 7.3 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CCM06628.1 - 3.5 5.4 14.0 4.5 5.0 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family Y_phosphatase PF00102.22 CCM06630.1 - 2.3e-50 171.1 0.0 6.8e-42 143.4 0.0 3.8 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 CCM06630.1 - 1.2e-07 32.0 0.0 3.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 CCM06630.1 - 0.063 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family VASP_tetra PF08776.6 CCM06630.1 - 0.08 12.2 0.6 0.95 8.8 0.0 2.3 2 0 0 2 2 2 0 VASP tetramerisation domain DSPc PF00782.15 CCM06630.1 - 0.28 10.7 0.0 0.5 9.9 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Chromo PF00385.19 CCM06632.1 - 5.6e-09 35.5 0.2 1.6e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Fungal_trans_2 PF11951.3 CCM06634.1 - 1.3e-17 63.5 0.0 1.5e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-SNARE_C PF12352.3 CCM06634.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Zn_clus PF00172.13 CCM06635.1 - 2.1e-06 27.5 8.0 3.6e-06 26.7 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HPP PF04982.8 CCM06638.1 - 2.9e-38 130.3 7.0 4.2e-38 129.8 4.9 1.2 1 0 0 1 1 1 1 HPP family PSGP PF07276.6 CCM06638.1 - 0.25 11.5 2.6 0.54 10.5 1.8 1.5 1 0 0 1 1 1 0 Apopolysialoglycoprotein (PSGP) Asp PF00026.18 CCM06639.1 - 3.6e-25 88.8 1.1 5.3e-22 78.4 0.8 2.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCM06639.1 - 1.6e-05 25.2 1.1 0.0001 22.7 0.3 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CCM06639.1 - 0.062 13.1 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.1 CCM06639.1 - 0.091 12.7 0.3 2.7 7.9 0.2 2.4 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Asp PF00026.18 CCM06640.1 - 2.7e-05 23.5 0.2 3.1e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Peroxidase_2 PF01328.12 CCM06641.1 - 8.9e-20 70.5 0.2 1.4e-19 69.9 0.2 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 TIP_N PF12457.3 CCM06642.1 - 0.093 12.8 3.7 0.14 12.2 2.2 1.5 1 1 0 1 1 1 0 Tuftelin interacting protein N terminal CDC45 PF02724.9 CCM06642.1 - 3.3 5.6 4.9 4 5.3 3.4 1.0 1 0 0 1 1 1 0 CDC45-like protein GAS PF13851.1 CCM06643.1 - 0.46 9.6 21.9 0.7 9.0 15.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2951 PF11166.3 CCM06643.1 - 5.2 6.9 8.5 17 5.3 3.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) APG6 PF04111.7 CCM06643.1 - 8.9 5.2 18.5 15 4.4 12.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ETX_MTX2 PF03318.8 CCM06644.1 - 4.1e-10 39.5 4.0 6.2e-10 39.0 2.8 1.3 1 1 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.15 CCM06644.1 - 2.3e-05 23.5 1.2 3e-05 23.1 0.8 1.1 1 0 0 1 1 1 1 Aerolysin toxin Binary_toxB PF03495.9 CCM06644.1 - 0.0052 15.4 5.2 0.014 14.0 3.4 1.8 1 1 0 1 1 1 1 Clostridial binary toxin B/anthrax toxin PA PKD PF00801.15 CCM06644.1 - 0.053 13.2 4.0 0.48 10.2 2.8 2.2 1 1 0 1 1 1 0 PKD domain PA-IIL PF07472.6 CCM06647.1 - 0.13 12.4 0.1 0.53 10.5 0.0 1.9 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) PA-IIL PF07472.6 CCM06648.1 - 0.0066 16.6 0.4 0.21 11.8 0.0 2.2 2 0 0 2 2 2 2 Fucose-binding lectin II (PA-IIL) WD40 PF00400.27 CCM06649.1 - 1.9e-14 52.8 2.6 5.5e-13 48.2 0.1 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCM06649.1 - 0.023 13.4 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Nup133 N terminal like Whib PF02467.11 CCM06650.1 - 0.099 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Transcription factor WhiB F-box-like PF12937.2 CCM06651.1 - 1.3e-06 27.9 4.9 2.5e-06 27.1 3.4 1.4 1 0 0 1 1 1 1 F-box-like TPR_MLP1_2 PF07926.7 CCM06651.1 - 0.017 14.8 2.4 0.024 14.3 1.7 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein MAD PF05557.8 CCM06651.1 - 0.072 11.1 2.4 0.092 10.8 1.7 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Tropomyosin PF00261.15 CCM06651.1 - 0.087 11.8 2.8 0.11 11.5 1.9 1.1 1 0 0 1 1 1 0 Tropomyosin F-box PF00646.28 CCM06651.1 - 0.15 11.7 3.2 0.39 10.4 2.2 1.7 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 CCM06652.1 - 2.5e-10 39.9 0.8 6.1e-10 38.6 0.6 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 CCM06652.1 - 0.87 9.3 5.6 0.91 9.3 0.1 3.8 5 0 0 5 5 5 0 Leucine rich repeat DUF2457 PF10446.4 CCM06652.1 - 1.4 7.5 10.0 1.8 7.1 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SH3_1 PF00018.23 CCM06653.1 - 0.003 16.8 0.2 0.0051 16.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCM06653.1 - 0.05 13.1 0.2 0.05 13.1 0.1 1.5 2 0 0 2 2 2 0 Variant SH3 domain Mito_carr PF00153.22 CCM06654.1 - 7.9e-17 60.7 0.0 8.4e-17 60.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.22 CCM06655.1 - 2.3e-22 78.4 0.4 2.5e-22 78.3 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Glyco_hydro_72 PF03198.9 CCM06656.1 - 6.6e-98 327.5 0.3 2.1e-52 178.1 0.2 2.0 2 0 0 2 2 2 2 Glucanosyltransferase X8 PF07983.8 CCM06656.1 - 3.1e-18 66.0 2.5 7.1e-18 64.8 1.7 1.6 1 0 0 1 1 1 1 X8 domain Flavin_Reduct PF01613.13 CCM06658.1 - 7.3e-24 84.3 0.0 1.1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain MACPF PF01823.14 CCM06659.1 - 0.00086 19.0 0.3 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 MAC/Perforin domain Laminin_G_3 PF13385.1 CCM06659.1 - 0.005 17.0 0.1 0.0094 16.1 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CHDCT2 PF08074.6 CCM06659.1 - 0.029 14.1 0.2 0.075 12.7 0.2 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF3228 PF11539.3 CCM06659.1 - 0.051 12.6 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) Acetyltransf_9 PF13527.1 CCM06660.1 - 0.0015 18.3 0.1 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 CCM06660.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.1 CCM06660.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RVT_1 PF00078.22 CCM06661.1 - 4.1e-06 26.3 0.0 1.2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PNRC PF15365.1 CCM06662.1 - 5 7.2 6.9 0.54 10.2 1.3 2.0 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator RVT_1 PF00078.22 CCM06663.1 - 1.4e-15 57.2 0.1 3.2e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PyrI PF01948.13 CCM06664.1 - 0.029 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Minor_capsid_3 PF12691.2 CCM06664.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage NB-ARC PF00931.17 CCM06665.1 - 3.7e-05 22.7 0.0 6.5e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 CCM06665.1 - 3.8e-05 23.4 0.3 0.00023 20.8 0.2 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CCM06665.1 - 0.00021 21.3 0.1 0.00065 19.7 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain Fanconi_A PF03511.9 CCM06665.1 - 0.09 12.5 0.0 0.84 9.4 0.0 2.5 3 0 0 3 3 3 0 Fanconi anaemia group A protein PMSR PF01625.16 CCM06666.1 - 9.4e-56 188.0 0.1 1.2e-55 187.7 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase p450 PF00067.17 CCM06667.1 - 2.6e-54 184.5 0.0 3.2e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.22 CCM06668.1 - 2.5e-18 66.2 0.1 6.1e-18 64.9 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aldedh PF00171.17 CCM06669.1 - 2.6e-09 35.9 0.1 2.8e-09 35.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 CCM06670.1 - 5e-17 62.3 0.0 4.5e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCM06670.1 - 1.9e-09 37.4 0.1 3.4e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCM06670.1 - 8.6e-07 28.6 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CCM06670.1 - 1.1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCM06670.1 - 0.00027 20.9 0.8 0.0005 20.1 0.5 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCM06670.1 - 0.0063 15.4 0.0 0.013 14.4 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein YjeF_N PF03853.10 CCM06670.1 - 0.044 13.3 0.1 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Shikimate_DH PF01488.15 CCM06670.1 - 0.1 12.7 0.7 0.25 11.4 0.5 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sulfatase_C PF14707.1 CCM06671.1 - 0.00019 21.7 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4109 PF13397.1 CCM06671.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) zf-C2H2_4 PF13894.1 CCM06673.1 - 0.083 13.2 1.7 0.083 13.2 1.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger CHORD PF04968.7 CCM06673.1 - 2.8 8.2 5.8 28 5.0 0.0 2.8 2 1 0 2 2 2 0 CHORD Nop10p PF04135.7 CCM06675.1 - 0.099 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family MFS_1 PF07690.11 CCM06676.1 - 2.2e-26 92.4 7.8 2.6e-26 92.1 5.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.6 CCM06676.1 - 0.028 13.5 1.6 0.04 13.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF3753 PF12575.3 CCM06676.1 - 0.93 9.3 3.2 0.71 9.7 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) 2TM PF13239.1 CCM06676.1 - 7.8 6.6 13.8 5.3 7.1 1.9 2.6 2 0 0 2 2 2 0 2TM domain Use1 PF09753.4 CCM06676.1 - 8 5.8 6.5 13 5.1 4.5 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Bax1-I PF01027.15 CCM06677.1 - 0.18 11.3 7.2 0.24 10.9 5.0 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF204 PF02659.10 CCM06677.1 - 0.78 9.9 4.5 4 7.6 3.1 2.2 1 1 0 1 1 1 0 Domain of unknown function DUF MARVEL PF01284.18 CCM06677.1 - 3.6 7.3 9.0 4.7 7.0 0.1 2.1 1 1 1 2 2 2 0 Membrane-associating domain p450 PF00067.17 CCM06679.1 - 4e-34 117.9 0.0 5e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM06680.1 - 2.1e-49 168.3 0.0 5.4e-49 166.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 DUF3435 PF11917.3 CCM06682.1 - 2.8e-33 115.2 0.8 6.2e-32 110.8 0.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 CCM06682.1 - 0.0083 15.8 0.2 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 Phage integrase family DUF4543 PF15076.1 CCM06682.1 - 0.059 13.4 0.3 3.8 7.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) AIP3 PF03915.8 CCM06684.1 - 4.5e-64 216.9 9.7 5.1e-64 216.7 6.7 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 Muted PF14942.1 CCM06684.1 - 0.0035 17.2 3.1 0.0035 17.2 2.2 2.2 2 1 0 2 2 2 1 Organelle biogenesis, Muted-like protein BEX PF04538.7 CCM06684.1 - 0.0056 16.8 3.0 0.073 13.2 0.2 2.3 2 0 0 2 2 2 1 Brain expressed X-linked like family Tmemb_cc2 PF10267.4 CCM06684.1 - 0.016 13.8 4.3 0.031 12.8 3.0 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1664 PF07889.7 CCM06684.1 - 0.017 14.8 4.6 0.048 13.4 2.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Tht1 PF04163.7 CCM06684.1 - 0.046 12.1 1.3 0.06 11.7 0.9 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein ISG65-75 PF11727.3 CCM06684.1 - 0.066 12.2 8.1 0.0098 14.9 1.5 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF3810 PF12725.2 CCM06684.1 - 0.16 10.8 0.9 0.25 10.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) WXG100 PF06013.7 CCM06684.1 - 0.16 12.0 3.9 4.4 7.3 0.2 3.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG EMP24_GP25L PF01105.19 CCM06684.1 - 0.24 11.1 5.1 1.2 8.8 3.4 2.2 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.6 CCM06684.1 - 0.58 10.0 13.1 0.37 10.7 1.0 3.5 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF1319 PF07028.6 CCM06684.1 - 0.8 9.9 11.3 1.9 8.6 4.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) NPV_P10 PF05531.7 CCM06684.1 - 0.96 9.7 6.2 9.3 6.5 3.7 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 CCM06684.1 - 2.3 7.7 10.0 0.88 9.0 4.4 2.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RicinB_lectin_2 PF14200.1 CCM06685.1 - 3e-09 37.1 2.5 1.8e-05 25.0 0.2 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF3712 PF12505.3 CCM06685.1 - 0.00018 21.4 0.0 0.00063 19.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3712) Gal-bind_lectin PF00337.17 CCM06685.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Galactoside-binding lectin Pkinase PF00069.20 CCM06689.1 - 1e-29 103.4 0.0 4.2e-29 101.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06689.1 - 1.3e-10 40.7 0.0 6.2e-05 22.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase RIO1 PF01163.17 CCM06689.1 - 0.0071 15.7 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Tir_receptor_C PF07489.6 CCM06690.1 - 0.01 15.6 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SdrG_C_C PF10425.4 CCM06690.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin p450 PF00067.17 CCM06692.1 - 4.2e-11 42.0 0.1 4.2e-11 42.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 CCM06693.1 - 2.7e-51 174.9 0.0 3.3e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCM06693.1 - 0.0008 19.0 0.2 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CCM06694.1 - 2.7e-09 36.3 0.0 3.3e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF2243 PF10002.4 CCM06694.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) NOD PF06816.8 CCM06694.1 - 0.15 11.1 0.0 0.39 9.8 0.0 1.7 1 0 0 1 1 1 0 NOTCH protein Flavokinase PF01687.12 CCM06695.1 - 5.4e-23 81.2 0.0 7e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Fungal_lectin PF07938.7 CCM06696.1 - 0.00022 20.6 0.0 0.00023 20.5 0.0 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin ABC_tran PF00005.22 CCM06697.1 - 1.4e-29 103.1 0.0 2.8e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CCM06697.1 - 2.4e-19 69.7 13.1 3.6e-19 69.2 9.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CCM06697.1 - 1.2e-05 24.6 2.3 0.0029 16.8 0.3 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCM06697.1 - 0.0013 18.7 0.2 0.11 12.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCM06697.1 - 0.0021 17.4 0.1 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCM06697.1 - 0.0084 16.1 0.4 0.021 14.8 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.12 CCM06697.1 - 0.0085 15.9 0.1 0.024 14.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_29 PF13555.1 CCM06697.1 - 0.017 14.6 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CCM06697.1 - 0.024 14.6 0.0 0.073 13.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CCM06697.1 - 0.041 13.3 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 CCM06697.1 - 0.071 12.8 0.2 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CCM06697.1 - 0.087 12.2 0.3 0.38 10.1 0.1 1.9 1 1 1 2 2 2 0 AAA-like domain AAA_17 PF13207.1 CCM06697.1 - 0.093 13.5 0.1 0.27 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Esterase_phd PF10503.4 CCM06698.1 - 0.12 11.6 0.1 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF3435 PF11917.3 CCM06699.1 - 8.3e-15 54.4 0.8 1e-11 44.2 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3435) ATG16 PF08614.6 CCM06704.1 - 0.028 14.2 0.2 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FdhE PF04216.7 CCM06704.1 - 0.065 12.9 0.5 0.086 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-H2C2_5 PF13909.1 CCM06705.1 - 0.0026 17.9 2.0 0.029 14.5 0.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 CCM06705.1 - 0.0068 16.6 0.1 0.0068 16.6 0.1 3.5 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM06705.1 - 0.31 11.4 0.1 0.31 11.4 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Ribosomal_L17 PF01196.14 CCM06706.1 - 0.19 12.2 7.1 48 4.6 0.2 4.8 1 1 3 4 4 4 0 Ribosomal protein L17 Ribosomal_L23eN PF03939.8 CCM06706.1 - 0.47 10.5 10.6 92 3.1 0.0 5.6 2 2 4 6 6 6 0 Ribosomal protein L23, N-terminal domain DUF3328 PF11807.3 CCM06707.1 - 6.8e-52 176.2 0.2 8.2e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HSF_DNA-bind PF00447.12 CCM06712.1 - 5.2e-20 71.5 0.0 1.1e-19 70.4 0.0 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding DUF1152 PF06626.7 CCM06713.1 - 0.0085 15.2 0.0 0.01 14.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1152) Pkinase PF00069.20 CCM06714.1 - 7e-13 48.3 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06714.1 - 2.8e-08 33.1 0.0 4.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM06714.1 - 0.00063 19.5 0.2 0.0079 15.9 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM06714.1 - 0.003 17.1 0.1 0.016 14.7 0.0 2.1 3 0 0 3 3 3 1 Choline/ethanolamine kinase Kdo PF06293.9 CCM06714.1 - 0.0086 15.1 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM06714.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family COQ7 PF03232.8 CCM06716.1 - 5.1e-63 211.6 0.4 4.2e-51 172.8 0.1 2.0 1 1 1 2 2 2 2 Ubiquinone biosynthesis protein COQ7 NDUF_B4 PF07225.7 CCM06717.1 - 1.3e-05 25.0 0.1 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.18 CCM06718.1 - 1.2e-13 50.6 1.6 2e-13 49.9 1.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CCM06718.1 - 3.4e-07 30.0 1.2 1.5e-06 27.9 0.8 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-C2H2_jaz PF12171.3 CCM06718.1 - 0.0001 22.3 0.3 0.00021 21.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCM06718.1 - 0.033 14.2 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CCM06718.1 - 0.04 14.2 0.4 0.083 13.2 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.2 CCM06718.1 - 0.071 13.3 0.5 0.13 12.5 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CCM06718.1 - 0.11 12.9 0.4 0.26 11.6 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger RED_N PF07808.8 CCM06718.1 - 3.6 6.7 11.9 0.12 11.6 2.8 2.1 2 1 0 2 2 2 0 RED-like protein N-terminal region Aldedh PF00171.17 CCM06719.1 - 1.6e-181 603.7 0.9 1.8e-181 603.5 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCM06719.1 - 0.0012 17.7 0.0 0.003 16.3 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 CCM06719.1 - 0.031 13.5 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) p450 PF00067.17 CCM06720.1 - 3.3e-48 164.3 0.0 3.7e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 CCM06722.1 - 4.5e-24 83.4 2.5 4.5e-09 35.8 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCM06722.1 - 0.06 12.8 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Sugar_tr PF00083.19 CCM06723.1 - 2.9e-34 118.4 25.6 5.8e-34 117.4 17.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM06723.1 - 2.7e-30 105.2 31.5 5.2e-30 104.3 21.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CCM06723.1 - 0.0013 18.5 4.7 0.27 11.0 0.1 2.8 3 0 0 3 3 3 2 MFS_1 like family B12D PF06522.6 CCM06725.1 - 0.81 9.4 3.4 4 7.2 0.9 2.4 1 1 1 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit AGTRAP PF06396.6 CCM06725.1 - 4.7 6.8 7.2 0.27 10.8 0.5 1.9 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) GFO_IDH_MocA PF01408.17 CCM06726.1 - 2.1e-25 89.5 0.1 4e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCM06726.1 - 4.7e-08 32.8 0.1 8.5e-06 25.5 0.0 3.0 3 1 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 CCM06726.1 - 0.0012 19.1 0.0 0.015 15.5 0.0 2.2 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain SspH PF08141.7 CCM06726.1 - 0.014 15.4 0.1 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein H family Methyltransf_25 PF13649.1 CCM06727.1 - 1.7e-06 28.3 0.0 5.8e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain GBA2_N PF12215.3 CCM06728.1 - 0.0014 17.8 0.2 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal CFEM PF05730.6 CCM06730.1 - 7.9e-11 41.6 15.6 1.3e-10 40.9 10.8 1.3 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 CCM06730.1 - 0.011 15.7 0.2 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 Gamma-thionin family DUF963 PF06131.6 CCM06732.1 - 0.012 14.8 10.0 0.012 14.8 6.9 3.0 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) APC2 PF08672.6 CCM06732.1 - 0.2 11.9 0.1 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 ORC6 PF05460.8 CCM06732.1 - 8.4 5.3 12.5 15 4.5 8.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Copper-fist PF00649.13 CCM06733.1 - 0.029 13.5 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain Pep_M12B_propep PF01562.14 CCM06733.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Reprolysin family propeptide CD99L2 PF12301.3 CCM06734.1 - 0.098 12.3 6.3 0.1 12.2 4.4 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Neisseria_TspB PF05616.8 CCM06734.1 - 2.5 6.3 9.0 3 6.1 6.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Herpes_LMP1 PF05297.6 CCM06734.1 - 3.5 6.4 8.8 4 6.2 6.1 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) LRR_7 PF13504.1 CCM06736.1 - 0.74 10.2 2.8 34 5.2 0.0 3.8 3 0 0 3 3 3 0 Leucine rich repeat DUF4027 PF13219.1 CCM06740.1 - 4.2 6.8 6.2 6.2 6.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4027) ABC_membrane PF00664.18 CCM06744.1 - 1.5e-11 44.2 8.1 7.5e-10 38.6 0.0 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region DUF2673 PF10880.3 CCM06745.1 - 1.2 9.2 5.8 0.4 10.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2673) Glyco_hydro_3 PF00933.16 CCM06746.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain AAA_2 PF07724.9 CCM06747.1 - 1.1e-50 171.8 0.0 5.8e-47 159.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CCM06747.1 - 7.3e-23 80.2 1.9 1.3e-22 79.4 0.2 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CCM06747.1 - 9.7e-23 80.8 0.0 9e-12 45.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.15 CCM06747.1 - 3e-16 59.0 6.4 4.5e-12 45.7 0.4 4.4 4 0 0 4 4 4 1 Clp amino terminal domain AAA_5 PF07728.9 CCM06747.1 - 4.4e-16 58.8 0.1 4.4e-08 32.9 0.0 3.8 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCM06747.1 - 3.9e-11 43.2 3.7 0.00027 20.9 0.0 4.8 2 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 CCM06747.1 - 2.3e-10 40.7 0.0 0.0016 18.5 0.0 4.0 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CCM06747.1 - 2.3e-08 33.6 0.0 3.8e-05 23.2 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 CCM06747.1 - 1.2e-06 28.1 0.0 0.0034 16.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCM06747.1 - 4.7e-06 25.9 0.0 0.01 15.0 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CCM06747.1 - 5.9e-06 26.6 0.0 0.019 15.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCM06747.1 - 9.6e-06 26.4 3.0 0.26 12.1 1.5 4.0 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 CCM06747.1 - 0.00011 21.0 2.4 0.27 9.9 0.0 3.4 3 1 1 4 4 4 2 TIP49 C-terminus Zeta_toxin PF06414.7 CCM06747.1 - 0.00016 20.8 0.4 0.014 14.4 0.0 3.1 3 1 1 4 4 4 1 Zeta toxin RNA_helicase PF00910.17 CCM06747.1 - 0.00019 21.5 0.1 1.1 9.4 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_24 PF13479.1 CCM06747.1 - 0.00034 20.2 0.0 0.014 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCM06747.1 - 0.00036 20.2 1.0 1.4 8.7 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_33 PF13671.1 CCM06747.1 - 0.00051 19.9 0.0 0.18 11.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCM06747.1 - 0.0031 17.1 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Laminin_II PF06009.7 CCM06747.1 - 0.0063 16.2 2.4 0.015 15.0 0.4 2.4 2 0 0 2 2 2 1 Laminin Domain II AAA_29 PF13555.1 CCM06747.1 - 0.014 14.9 0.0 7.4 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCM06747.1 - 0.015 15.6 0.6 3 8.1 0.0 3.2 3 0 0 3 3 3 0 ABC transporter Torsin PF06309.6 CCM06747.1 - 0.035 14.0 0.0 0.4 10.5 0.0 2.4 3 0 0 3 3 2 0 Torsin Arch_ATPase PF01637.13 CCM06747.1 - 0.058 13.0 3.8 3.5 7.2 0.1 4.2 4 1 0 4 4 3 0 Archaeal ATPase DUF258 PF03193.11 CCM06747.1 - 0.083 12.0 0.0 4.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCM06747.1 - 0.084 12.2 4.0 4.3 6.6 0.0 3.9 3 1 0 3 3 3 0 AAA-like domain MAD PF05557.8 CCM06747.1 - 0.11 10.5 8.9 0.2 9.6 6.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein AAA_25 PF13481.1 CCM06747.1 - 0.15 11.4 3.7 9.9 5.5 0.0 3.6 3 1 1 4 4 4 0 AAA domain DUF4337 PF14235.1 CCM06747.1 - 0.77 9.5 7.7 0.51 10.1 3.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) AAA_13 PF13166.1 CCM06747.1 - 5.1 5.4 8.8 1.3 7.3 3.8 1.7 2 0 0 2 2 2 0 AAA domain Mnd1 PF03962.10 CCM06747.1 - 9 5.9 10.5 10 5.7 6.0 2.0 1 1 0 1 1 1 0 Mnd1 family zf-CHCC PF10276.4 CCM06748.1 - 4.6e-11 42.3 1.2 6.8e-11 41.8 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.20 CCM06749.1 - 1.2e-56 191.7 0.0 2.3e-56 190.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06749.1 - 6.5e-24 84.3 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CAF-1_p150 PF11600.3 CCM06749.1 - 0.14 11.4 8.5 0.3 10.4 5.9 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LsmAD PF06741.8 CCM06749.1 - 0.5 10.5 2.7 1.1 9.4 1.8 1.5 1 0 0 1 1 1 0 LsmAD domain HVSL PF09749.4 CCM06750.1 - 0.017 14.1 0.0 0.017 14.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein Helicase_C PF00271.26 CCM06752.1 - 1.2e-09 37.9 0.0 1.2e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PspA_IM30 PF04012.7 CCM06753.1 - 4.8e-05 22.8 0.0 5.3e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 PspA/IM30 family Baculo_PEP_C PF04513.7 CCM06753.1 - 0.001 18.8 2.1 0.0014 18.4 1.4 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CCM06753.1 - 0.0025 17.0 0.1 0.0027 16.9 0.1 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF2730 PF10805.3 CCM06753.1 - 0.019 14.6 0.2 0.039 13.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Fib_alpha PF08702.5 CCM06753.1 - 0.021 14.9 0.1 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Paramyx_P_V_C PF03210.8 CCM06753.1 - 0.029 14.2 3.8 1.3 8.8 2.5 2.3 1 1 1 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal HTH_11 PF08279.7 CCM06753.1 - 0.041 13.5 1.4 6 6.5 0.1 3.1 1 1 1 3 3 3 0 HTH domain WEMBL PF05701.6 CCM06753.1 - 0.044 12.2 0.0 0.047 12.1 0.0 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FlaC_arch PF05377.6 CCM06753.1 - 0.047 13.5 0.5 0.48 10.3 0.3 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 CCM06753.1 - 0.049 12.2 0.0 0.054 12.1 0.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.1 CCM06753.1 - 0.051 12.0 0.0 0.054 11.9 0.0 1.0 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 CCM06753.1 - 0.061 13.2 0.0 0.073 12.9 0.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Prefoldin PF02996.12 CCM06753.1 - 0.078 12.6 0.5 0.26 10.9 0.3 1.8 1 1 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.7 CCM06753.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 CCM06753.1 - 0.094 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HsbA PF12296.3 CCM06753.1 - 0.12 12.2 4.2 0.19 11.6 2.4 1.6 1 1 1 2 2 2 0 Hydrophobic surface binding protein A NUMOD3 PF07460.6 CCM06754.1 - 0.12 12.2 7.5 49 3.9 0.0 4.0 4 0 0 4 4 4 0 NUMOD3 motif (2 copies) Sds3 PF08598.6 CCM06758.1 - 0.24 10.8 2.0 1.1 8.7 0.1 1.9 2 0 0 2 2 2 0 Sds3-like Pyridoxal_deC PF00282.14 CCM06759.1 - 3.1e-18 65.3 0.0 8.6e-13 47.4 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Pkinase PF00069.20 CCM06760.1 - 8.7e-13 48.0 0.1 1.7e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM06760.1 - 1.6e-08 33.9 0.0 2.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCM06760.1 - 0.0027 17.4 0.1 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCM06760.1 - 0.008 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CCM06760.1 - 0.014 14.4 0.0 0.014 14.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCM06760.1 - 0.05 12.9 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family F-box PF00646.28 CCM06761.1 - 1.5e-05 24.4 0.2 7.4e-05 22.2 0.2 2.3 1 0 0 1 1 1 1 F-box domain Prenyltransf PF01255.14 CCM06762.1 - 1e-75 253.6 0.0 1.3e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.19 CCM06762.1 - 0.11 11.7 0.1 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel zf-CCHC PF00098.18 CCM06767.1 - 3.3e-06 26.7 3.4 7.8e-06 25.5 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 CCM06767.1 - 0.001 18.9 1.8 0.0023 17.8 1.3 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.1 CCM06767.1 - 0.45 10.0 4.3 1.2 8.6 2.7 1.8 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger MIS13 PF08202.6 CCM06771.1 - 2.3e-28 99.1 5.5 2.3e-28 99.1 3.8 2.0 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Cytochrom_C PF00034.16 CCM06772.1 - 6.4e-09 36.5 0.1 1.3e-08 35.5 0.1 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CCM06772.1 - 2.8e-08 33.8 1.8 2e-07 31.0 1.3 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CCM06772.1 - 0.00058 19.3 1.4 0.0032 16.9 1.0 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain RHSP PF07999.6 CCM06773.1 - 0.13 10.8 0.1 2.1 6.8 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon hot spot protein AAA_10 PF12846.2 CCM06773.1 - 0.13 11.6 0.0 0.4 10.0 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 CCM06773.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mid2 PF04478.7 CCM06774.1 - 0.0045 16.4 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Shisa PF13908.1 CCM06774.1 - 0.052 13.7 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ABC1 PF03109.11 CCM06775.1 - 2.1e-27 95.4 0.1 3.9e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 CCM06775.1 - 0.0075 16.0 0.7 0.15 11.7 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family adh_short PF00106.20 CCM06776.1 - 3.3e-30 105.1 3.3 4e-30 104.9 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCM06776.1 - 2.1e-15 57.1 0.1 2.8e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCM06776.1 - 1e-09 38.2 3.3 1.8e-09 37.4 2.3 1.3 1 1 0 1 1 1 1 KR domain DUF881 PF05949.7 CCM06776.1 - 0.13 11.7 1.5 0.19 11.1 1.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) DUF3024 PF11225.3 CCM06777.1 - 2.3e-05 24.1 8.8 21 5.0 0.0 6.0 3 2 3 6 6 6 5 Protein of unknown function (DUF3024) DUF3461 PF11944.3 CCM06777.1 - 0.025 14.4 7.2 0.17 11.6 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) DUF2971 PF11185.3 CCM06777.1 - 0.28 11.9 6.7 64 4.3 4.2 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2971) Ribosomal_L17 PF01196.14 CCM06777.1 - 4.4 7.9 7.8 26 5.4 0.6 2.8 1 1 1 2 2 2 0 Ribosomal protein L17 DUF3328 PF11807.3 CCM06778.1 - 4.6e-28 98.3 0.5 5.3e-28 98.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UDPGT PF00201.13 CCM06778.1 - 0.12 10.8 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF3328 PF11807.3 CCM06779.1 - 7.4e-10 38.8 0.0 7.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Multi_ubiq PF14452.1 CCM06779.1 - 0.0077 16.1 0.0 0.0084 16.0 0.0 1.0 1 0 0 1 1 1 1 Multiubiquitin Auxin_BP PF02041.11 CCM06780.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein RVT_2 PF07727.9 CCM06782.1 - 2e-32 112.1 0.0 2.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCM06782.1 - 0.0024 17.9 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCM06782.1 - 0.043 13.4 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain TMEM240 PF15207.1 CCM06783.1 - 0.059 12.9 0.0 0.059 12.9 0.0 1.4 2 0 0 2 2 2 0 TMEM240 family E1-E2_ATPase PF00122.15 CCM06783.1 - 0.48 9.4 2.4 0.66 8.9 1.6 1.1 1 0 0 1 1 1 0 E1-E2 ATPase DUF2109 PF09882.4 CCM06783.1 - 0.76 9.7 5.0 0.33 10.9 0.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Neurensin PF14927.1 CCM06783.1 - 1.2 8.4 4.6 21 4.4 3.2 2.1 1 1 0 1 1 1 0 Neurensin DUF1049 PF06305.6 CCM06783.1 - 1.4 8.4 14.6 0.65 9.5 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF4131 PF13567.1 CCM06783.1 - 3.2 7.1 9.3 7.5 5.9 6.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3328 PF11807.3 CCM06783.1 - 5.4 6.6 6.5 1.4 8.5 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) NUDIX_4 PF14815.1 CCM06786.1 - 0.034 13.5 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 NUDIX domain zf-C2H2 PF00096.21 CCM06787.1 - 1.9e-19 68.7 17.0 1.5e-05 25.0 1.0 6.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCM06787.1 - 1.1e-14 53.8 24.2 8.3e-07 28.9 1.2 6.0 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCM06787.1 - 5.5e-06 26.3 36.7 0.0078 16.4 0.1 7.2 8 0 0 8 8 8 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCM06787.1 - 0.00035 20.3 11.3 0.59 10.1 0.3 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCM06787.1 - 0.00036 20.5 2.2 0.013 15.6 0.3 3.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 CCM06787.1 - 0.0052 16.4 7.7 0.47 10.1 0.0 4.3 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-met PF12874.2 CCM06787.1 - 0.37 11.0 3.9 6.4 7.1 0.1 3.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF629 PF04780.7 CCM06787.1 - 1.9 6.9 3.0 22 3.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF629) RTA1 PF04479.8 CCM06794.1 - 1e-32 113.4 1.6 2e-32 112.5 0.6 1.7 1 1 1 2 2 2 1 RTA1 like protein DUF1189 PF06691.6 CCM06795.1 - 0.07 12.4 0.6 0.079 12.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) DUF3412 PF11892.3 CCM06795.1 - 0.13 12.0 0.1 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) RVT_1 PF00078.22 CCM06796.1 - 8.4e-11 41.6 0.0 1.5e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bd3614-deam PF14439.1 CCM06797.1 - 0.056 13.3 0.2 0.063 13.1 0.1 1.1 1 0 0 1 1 1 0 Bd3614-like deaminase SNF2_N PF00176.18 CCM06798.1 - 5.7e-08 31.9 0.0 1.5e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCM06798.1 - 3.9e-07 29.8 0.0 9.8e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCM06798.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pyr_redox PF00070.22 CCM06798.1 - 0.19 12.1 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OPT PF03169.10 CCM06802.1 - 2.1e-125 419.5 21.3 2.5e-125 419.3 14.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Aldo_ket_red PF00248.16 CCM06803.1 - 1.7e-66 223.9 0.0 1.9e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1722 PF08349.6 CCM06803.1 - 0.047 13.5 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF2532 PF10811.3 CCM06803.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) F-box-like PF12937.2 CCM06804.1 - 0.00056 19.5 0.4 0.002 17.8 0.3 2.0 1 0 0 1 1 1 1 F-box-like HpcH_HpaI PF03328.9 CCM06807.1 - 9.7e-27 93.2 0.0 4.4e-19 68.2 0.0 2.1 2 0 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 CCM06807.1 - 0.025 13.2 0.0 0.036 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain HET PF06985.6 CCM06808.1 - 6.8e-24 84.6 0.0 1.3e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DcpS_C PF11969.3 CCM06810.1 - 5e-24 84.7 0.0 8.1e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 CCM06810.1 - 3e-19 69.4 0.0 5.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Peroxidase_2 PF01328.12 CCM06811.1 - 2.6e-23 82.1 1.9 1.1e-19 70.2 0.6 2.2 2 0 0 2 2 2 2 Peroxidase, family 2 Gmad1 PF10647.4 CCM06812.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain DUF29 PF01724.11 CCM06813.1 - 0.033 14.0 2.4 4.3 7.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF29 Daxx PF03344.10 CCM06813.1 - 2.5 6.4 14.3 3.6 5.9 9.9 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CCM06813.1 - 3.4 5.4 15.9 5.4 4.7 11.0 1.3 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 CCM06822.1 - 1.8e-26 92.6 27.5 9.2e-20 70.6 14.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.7 CCM06822.1 - 0.0057 15.0 0.0 2 6.7 0.0 2.2 2 0 0 2 2 2 2 Ferroportin1 (FPN1) ATG22 PF11700.3 CCM06822.1 - 0.052 12.0 12.5 0.016 13.6 4.8 2.2 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Retrotrans_gag PF03732.12 CCM06823.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_2 PF07727.9 CCM06824.1 - 2.6e-44 151.0 0.0 3.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCM06824.1 - 1.4e-18 67.1 0.0 5.6e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CCM06824.1 - 2.5e-10 39.8 0.0 6.5e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 CCM06824.1 - 8.2e-07 28.8 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CCM06824.1 - 0.0022 17.5 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CCM06824.1 - 0.03 13.8 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain UBN2_3 PF14244.1 CCM06824.1 - 0.05 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 CCM06825.1 - 0.082 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3699 PF12480.3 CCM06826.1 - 0.072 12.7 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) DUF2393 PF09624.5 CCM06826.1 - 0.63 9.5 9.7 0.03 13.8 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2393) DUF4131 PF13567.1 CCM06826.1 - 1.7 8.0 7.6 2.6 7.4 5.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Choline_transpo PF04515.7 CCM06826.1 - 9.1 4.9 12.0 12 4.5 6.5 1.8 1 1 1 2 2 2 0 Plasma-membrane choline transporter ATP-synt_8 PF00895.15 CCM06828.1 - 3.4 7.9 14.4 0.26 11.5 3.4 2.2 2 0 0 2 2 2 0 ATP synthase protein 8 DIOX_N PF14226.1 CCM06830.1 - 4.9e-14 52.8 0.1 1.1e-13 51.6 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCM06830.1 - 8.9e-11 41.9 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3328 PF11807.3 CCM06831.1 - 4.4e-35 121.3 4.7 4.9e-35 121.1 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) YagB_YeeU_YfjZ PF06154.6 CCM06831.1 - 0.054 13.7 0.1 0.11 12.6 0.1 1.5 1 1 0 1 1 1 0 YagB/YeeU/YfjZ family Flavokinase PF01687.12 CCM06832.1 - 2e-24 85.8 0.0 2.6e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Fungal_lectin PF07938.7 CCM06833.1 - 1.5e-06 27.7 0.2 4.6e-06 26.1 0.1 1.7 1 1 1 2 2 2 1 Fungal fucose-specific lectin AMP-binding PF00501.23 CCM06837.1 - 8.9e-29 100.1 0.0 5.8e-27 94.1 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme DUF3328 PF11807.3 CCM06839.1 - 2.2e-08 34.0 0.0 3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF29 PF01724.11 CCM06840.1 - 0.019 14.8 0.5 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF29 GvpL_GvpF PF06386.6 CCM06840.1 - 0.07 12.7 2.0 3.7 7.0 0.0 2.4 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Daxx PF03344.10 CCM06840.1 - 0.26 9.7 15.1 0.26 9.7 9.6 1.4 1 1 0 1 1 1 0 Daxx Family CTP_transf_1 PF01148.15 CCM06842.1 - 0.029 14.0 8.0 0.035 13.7 5.5 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family Ibs_toxin PF13956.1 CCM06842.1 - 0.092 12.5 0.3 0.092 12.5 0.2 2.2 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system EmrE PF13536.1 CCM06842.1 - 0.17 12.1 6.1 0.1 12.8 3.0 1.6 1 1 0 1 1 1 0 Multidrug resistance efflux transporter TraL PF07178.6 CCM06842.1 - 0.2 11.6 5.1 3.8 7.6 0.7 2.0 1 1 1 2 2 2 0 TraL protein DUF443 PF04276.7 CCM06842.1 - 0.21 11.0 5.1 0.27 10.6 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF4131 PF13567.1 CCM06842.1 - 0.22 10.9 4.6 0.28 10.5 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PTS_EIIC_2 PF13303.1 CCM06842.1 - 0.72 8.6 7.7 0.85 8.4 5.4 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF4064 PF13273.1 CCM06842.1 - 0.84 9.7 5.3 1.6 8.8 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Yip1 PF04893.12 CCM06842.1 - 1.9 7.9 12.1 3.9 6.9 8.1 1.6 1 1 0 1 1 1 0 Yip1 domain SUR7 PF06687.7 CCM06842.1 - 4.2 6.8 10.8 5.4 6.5 7.5 1.1 1 0 0 1 1 1 0 SUR7/PalI family PRA1 PF03208.14 CCM06842.1 - 7.9 5.8 10.2 10 5.4 7.1 1.1 1 0 0 1 1 1 0 PRA1 family protein DUF3329 PF11808.3 CCM06842.1 - 8.5 6.5 7.1 1.8 8.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DUF3328 PF11807.3 CCM06845.1 - 2.3e-35 122.2 4.3 2.7e-35 122.0 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 CCM06847.1 - 2.4e-51 174.5 20.0 3.6e-34 118.0 0.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 CCM06847.1 - 5.4e-05 21.8 27.2 0.0018 16.8 6.6 2.3 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 CCM06847.1 - 0.0045 16.7 0.2 0.0045 16.7 0.1 3.2 4 1 0 4 4 4 1 MFS_1 like family OATP PF03137.15 CCM06847.1 - 0.016 13.2 2.7 2.9 5.8 0.0 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MF_alpha_N PF05436.6 CCM06847.1 - 0.018 14.7 0.5 0.25 11.0 0.0 2.7 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus DUF3487 PF11990.3 CCM06847.1 - 1.1 8.6 0.0 1.1 8.6 0.0 3.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3487) p450 PF00067.17 CCM06848.1 - 7.8e-46 156.5 0.0 9.3e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TEX12 PF15219.1 CCM06851.1 - 0.043 13.8 0.6 0.35 10.8 0.1 2.4 2 0 0 2 2 2 0 Testis-expressed 12 Sugar_tr PF00083.19 CCM06853.1 - 2.9e-82 276.6 26.8 3.8e-82 276.2 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM06853.1 - 2.5e-32 111.9 42.7 4.5e-24 84.8 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCM06853.1 - 1.7e-07 29.9 3.9 1.7e-07 29.9 2.7 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein F-box-like PF12937.2 CCM06855.1 - 2e-06 27.4 0.1 7e-06 25.6 0.1 2.1 1 0 0 1 1 1 1 F-box-like zf-C2H2_4 PF13894.1 CCM06857.1 - 3.7e-05 23.7 0.2 0.35 11.3 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCM06857.1 - 0.0035 17.5 0.1 0.3 11.5 0.0 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2 PF00096.21 CCM06858.1 - 0.00056 20.1 3.6 0.17 12.3 0.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCM06858.1 - 0.057 13.7 4.3 3.4 8.1 0.9 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CCM06858.1 - 0.17 12.1 1.3 2.1 8.7 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain RVP_2 PF08284.6 CCM06860.1 - 0.042 13.7 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease adh_short PF00106.20 CCM06864.1 - 1.6e-11 44.4 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCM06864.1 - 4e-08 33.1 0.0 5.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.17 CCM06866.1 - 3.4e-41 141.2 0.0 4.1e-28 98.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 WD40 PF00400.27 CCM06867.1 - 4e-20 70.8 15.8 6.1e-09 35.4 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF3312 PF11768.3 CCM06867.1 - 0.47 8.6 0.0 0.68 8.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) RrnaAD PF00398.15 CCM06868.1 - 7.2e-21 74.3 0.0 1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF747 PF05346.6 CCM06869.1 - 5.2e-76 255.8 6.2 9.1e-76 255.0 4.3 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family SMC_N PF02463.14 CCM06869.1 - 4.8e-43 146.9 1.6 7.3e-43 146.3 1.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCM06869.1 - 6e-26 90.7 0.1 3.4e-25 88.3 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCM06869.1 - 1e-06 28.9 0.8 3.6e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 CCM06869.1 - 0.00023 20.4 21.2 0.047 12.8 0.3 4.8 2 2 1 4 4 4 3 Reovirus sigma C capsid protein ICAP-1_inte_bdg PF10480.4 CCM06870.1 - 0.99 9.1 8.5 1.8 8.3 5.9 1.3 1 0 0 1 1 1 0 Beta-1 integrin binding protein DUF4363 PF14276.1 CCM06873.1 - 0.042 13.5 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) LAT PF15234.1 CCM06873.1 - 0.057 12.8 1.3 0.061 12.7 0.9 1.0 1 0 0 1 1 1 0 Linker for activation of T-cells DUF4131 PF13567.1 CCM06873.1 - 0.12 11.7 0.5 0.12 11.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ATP-synt_8 PF00895.15 CCM06873.1 - 5 7.3 11.6 0.9 9.7 5.3 1.9 2 1 0 2 2 2 0 ATP synthase protein 8 CTP_transf_2 PF01467.21 CCM06878.1 - 6.4e-10 39.2 0.0 1.8e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 CCM06878.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase p450 PF00067.17 CCM06879.1 - 2.7e-68 230.5 0.0 3.3e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 CCM06880.1 - 2.4e-06 26.8 0.0 3.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain p450 PF00067.17 CCM06881.1 - 5.6e-57 193.2 0.0 6e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidoligase_2 PF12224.3 CCM06886.1 - 0.038 13.6 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme CoatB PF10389.4 CCM06889.1 - 0.028 14.2 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage coat protein B DUF2976 PF11190.3 CCM06889.1 - 0.1 12.1 0.2 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) COX14 PF14880.1 CCM06889.1 - 0.11 12.0 0.4 0.15 11.6 0.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly RVT_1 PF00078.22 CCM06890.1 - 4.8e-18 65.2 0.1 8.2e-18 64.5 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC2_membrane_3 PF12698.2 CCM06891.1 - 0.12 11.4 3.6 0.17 10.9 2.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SUR7 PF06687.7 CCM06891.1 - 0.74 9.3 5.3 0.99 8.9 3.7 1.2 1 0 0 1 1 1 0 SUR7/PalI family VirB3 PF05101.8 CCM06891.1 - 5.7 6.9 7.5 0.48 10.4 0.3 2.1 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein DnaB PF00772.16 CCM06896.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain WD40 PF00400.27 CCM06898.1 - 4.9e-143 460.5 66.8 6.1e-12 44.9 0.2 13.5 12 1 1 13 13 13 13 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCM06898.1 - 3.3e-16 59.0 44.4 0.0045 15.7 0.1 11.3 1 1 8 9 9 9 8 Nup133 N terminal like Nup160 PF11715.3 CCM06898.1 - 3.7e-11 41.8 31.3 0.78 7.8 0.3 10.7 1 1 8 9 9 9 7 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CCM06898.1 - 8.9e-08 32.1 12.6 0.59 10.4 0.0 9.9 7 4 5 12 12 12 2 PQQ-like domain PD40 PF07676.7 CCM06898.1 - 1.1e-07 31.2 5.3 24 4.7 0.0 10.4 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat DUF2375 PF09558.5 CCM06898.1 - 1.6e-06 27.8 0.0 22 4.9 0.0 8.0 8 1 1 9 9 9 0 Protein of unknown function (DUF2375) Cytochrom_D1 PF02239.11 CCM06898.1 - 1.8e-06 26.5 13.0 0.5 8.5 0.1 6.0 3 2 3 7 7 7 4 Cytochrome D1 heme domain PQQ_2 PF13360.1 CCM06898.1 - 3.2e-06 26.7 18.2 0.028 13.8 1.6 6.0 1 1 4 5 5 5 5 PQQ-like domain SoxZ PF08770.6 CCM06898.1 - 0.15 11.4 0.0 57 3.2 0.0 4.3 4 1 0 4 4 4 0 Sulphur oxidation protein SoxZ VID27 PF08553.5 CCM06898.1 - 0.68 8.0 2.4 22 3.0 0.0 3.4 4 0 0 4 4 4 0 VID27 cytoplasmic protein FG-GAP_2 PF14312.1 CCM06898.1 - 0.92 9.5 45.7 35 4.4 0.0 12.5 13 0 0 13 13 13 0 FG-GAP repeat RVT_1 PF00078.22 CCM06899.1 - 2.2e-17 63.1 0.0 2.6e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CCM06900.1 - 1.9e-08 33.9 0.0 4.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase EFP_N PF08207.7 CCM06900.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Exo_endo_phos PF03372.18 CCM06900.1 - 0.0056 16.6 0.3 0.0056 16.6 0.2 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M15_4 PF13539.1 CCM06900.1 - 0.084 13.3 0.1 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DUF4005 PF13178.1 CCM06901.1 - 0.0093 16.1 1.6 0.028 14.6 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4005) zf-ribbon_3 PF13248.1 CCM06901.1 - 0.023 13.8 0.7 0.023 13.8 0.5 2.9 3 0 0 3 3 3 0 zinc-ribbon domain RVT_1 PF00078.22 CCM06905.1 - 0.00021 20.7 0.0 0.00053 19.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCM06906.1 - 2.6e-14 53.0 0.1 3.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Frataxin_Cyay PF01491.11 CCM06908.1 - 0.034 13.9 1.1 0.097 12.4 0.2 1.8 1 1 1 2 2 2 0 Frataxin-like domain Occludin_ELL PF07303.8 CCM06908.1 - 0.11 13.1 1.1 0.15 12.8 0.8 1.3 1 0 0 1 1 1 0 Occludin homology domain DUF2968 PF11180.3 CCM06908.1 - 0.13 11.6 1.5 1.4 8.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF16 PF01519.11 CCM06908.1 - 0.15 12.2 3.6 0.2 11.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 FlxA PF14282.1 CCM06908.1 - 1.1 9.2 4.8 1.4 8.9 3.1 1.4 1 1 0 1 1 1 0 FlxA-like protein RRM_1 PF00076.17 CCM06911.1 - 3.9e-08 32.8 0.0 8.8e-08 31.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM06911.1 - 1.4e-07 31.4 0.0 4.1e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCM06911.1 - 1.4e-05 24.8 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCM06911.1 - 0.0047 16.6 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 CCM06911.1 - 0.05 13.4 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_Packaging PF11053.3 CCM06911.1 - 0.058 13.0 0.3 0.13 11.8 0.2 1.6 1 1 0 1 1 1 0 Terminase DNA packaging enzyme RRM_1 PF00076.17 CCM06912.1 - 2.6e-10 39.7 0.0 4.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCM06912.1 - 2.9e-09 36.7 0.0 4.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCM06912.1 - 2.2e-05 24.2 0.0 4.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCM06912.1 - 7.4e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif EHN PF06441.7 CCM06913.1 - 1.4e-66 221.4 1.0 1e-31 109.1 0.0 3.4 4 0 0 4 4 4 2 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CCM06913.1 - 5e-21 75.6 3.5 5e-10 39.6 0.0 3.0 2 2 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM06913.1 - 7e-16 58.4 0.2 5.8e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold cobW PF02492.14 CCM06915.1 - 5.1e-32 110.7 0.0 6.4e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CCM06915.1 - 0.00021 20.1 0.1 0.053 12.2 0.0 2.1 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 CCM06915.1 - 0.0058 16.0 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CCM06915.1 - 0.0059 16.5 0.0 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 CCM06915.1 - 0.034 14.9 0.1 0.061 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCM06915.1 - 0.069 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 CCM06915.1 - 0.098 12.0 0.0 4.4 6.7 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.12 CCM06915.1 - 0.098 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 CCM06915.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCM06915.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CCM06915.1 - 0.16 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus Methyltransf_11 PF08241.7 CCM06916.1 - 2.5e-18 66.3 0.0 5.7e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCM06916.1 - 1.7e-17 63.3 0.0 2.6e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCM06916.1 - 4.6e-17 62.1 0.0 6.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM06916.1 - 1.2e-14 54.7 0.0 2.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM06916.1 - 3.6e-13 49.8 0.0 5.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCM06916.1 - 7.6e-11 41.5 0.1 9.3e-09 34.7 0.0 2.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CCM06916.1 - 1.2e-10 41.5 0.0 2.9e-10 40.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 CCM06916.1 - 1.8e-09 37.1 0.0 3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 CCM06916.1 - 3.6e-09 36.4 0.1 8.1e-09 35.3 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 CCM06916.1 - 6.8e-08 31.5 0.0 9e-08 31.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 CCM06916.1 - 1.3e-06 28.4 0.4 3.4e-06 27.0 0.3 1.7 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CCM06916.1 - 0.00025 20.0 0.0 0.00033 19.6 0.0 1.4 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.1 CCM06916.1 - 0.0005 19.7 0.6 0.0016 18.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.5 CCM06916.1 - 0.0005 19.6 0.0 0.00073 19.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit ADH_zinc_N PF00107.21 CCM06916.1 - 0.00051 19.5 0.2 0.0019 17.7 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PrmA PF06325.8 CCM06916.1 - 0.00062 18.9 0.1 0.0044 16.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 CCM06916.1 - 0.00083 18.5 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 CCM06916.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 CCM06916.1 - 0.0061 15.6 0.0 0.0082 15.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 CCM06916.1 - 0.0084 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DUF938 PF06080.7 CCM06916.1 - 0.011 15.2 0.0 0.035 13.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Fibrillarin PF01269.12 CCM06916.1 - 0.036 12.9 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin DUF433 PF04255.9 CCM06916.1 - 0.061 12.7 0.0 0.26 10.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF433) CheR PF01739.13 CCM06916.1 - 0.16 11.2 0.0 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain ABC2_membrane_3 PF12698.2 CCM06917.1 - 0.058 12.4 8.1 0.075 12.0 5.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF373 PF04123.8 CCM06917.1 - 0.87 8.5 3.6 1.6 7.6 2.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) zf-DHHC PF01529.15 CCM06917.1 - 2.8 7.3 5.3 8.9 5.6 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase SUR7 PF06687.7 CCM06917.1 - 2.8 7.4 7.8 7.2 6.1 5.4 1.7 1 1 0 1 1 1 0 SUR7/PalI family Med13_C PF06333.7 CCM06918.1 - 0.32 9.4 1.6 0.4 9.1 1.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal zf-ribbon_3 PF13248.1 CCM06919.1 - 0.0049 16.0 0.7 0.011 14.9 0.5 1.6 1 0 0 1 1 1 1 zinc-ribbon domain RVT_1 PF00078.22 CCM06920.1 - 2.5e-24 85.8 0.0 4.2e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CCM06920.1 - 4.2e-08 32.8 0.1 8.9e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase EFP_N PF08207.7 CCM06920.1 - 0.0015 18.3 0.1 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Exo_endo_phos PF03372.18 CCM06920.1 - 0.0049 16.8 0.4 0.011 15.6 0.3 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-MIZ PF02891.15 CCM06923.1 - 0.041 13.4 2.1 12 5.4 0.1 3.1 2 1 1 3 3 3 0 MIZ/SP-RING zinc finger ATP-synt_8 PF00895.15 CCM06923.1 - 0.074 13.2 0.8 0.074 13.2 0.5 3.0 2 1 0 2 2 2 0 ATP synthase protein 8 zf-DHHC PF01529.15 CCM06923.1 - 0.45 9.8 5.1 0.75 9.1 3.5 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase CTP_transf_1 PF01148.15 CCM06923.1 - 0.65 9.5 5.5 0.7 9.4 3.8 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family DUF4064 PF13273.1 CCM06923.1 - 1.3 9.1 6.4 16 5.6 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4395 PF14340.1 CCM06923.1 - 3 7.9 9.2 5.6 7.0 6.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) DUF3329 PF11808.3 CCM06923.1 - 5 7.2 9.4 8 6.6 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) SUR7 PF06687.7 CCM06923.1 - 6.8 6.1 14.2 24 4.3 9.9 1.8 1 1 0 1 1 1 0 SUR7/PalI family DUF3753 PF12575.3 CCM06923.1 - 8.2 6.3 10.2 12 5.8 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) RVT_1 PF00078.22 CCM06924.1 - 0.058 12.7 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CCM06925.1 - 3.2e-11 42.7 0.2 1.9e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain VirB3 PF05101.8 CCM06926.1 - 0.045 13.7 3.0 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein SUR7 PF06687.7 CCM06926.1 - 0.11 12.0 3.6 0.24 10.9 2.4 1.5 1 1 0 1 1 1 0 SUR7/PalI family ABC2_membrane_3 PF12698.2 CCM06926.1 - 0.17 10.8 3.4 0.25 10.3 2.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2393 PF09624.5 CCM06926.1 - 0.45 10.0 3.1 0.21 11.0 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) DUF2244 PF10003.4 CCM06926.1 - 0.74 9.1 4.6 0.23 10.7 0.1 2.1 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) ATP-synt_8 PF00895.15 CCM06926.1 - 2.1 8.6 10.3 0.28 11.4 0.9 2.5 2 1 0 2 2 2 0 ATP synthase protein 8 DUF3329 PF11808.3 CCM06926.1 - 8.7 6.5 6.5 2.9 8.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) WD40 PF00400.27 CCM06928.1 - 1.1e-49 164.6 17.6 1e-12 47.3 0.2 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCM06928.1 - 2.6e-07 29.7 9.8 0.028 13.1 0.1 4.0 1 1 3 4 4 4 3 Nup133 N terminal like BBS2_Mid PF14783.1 CCM06928.1 - 6e-06 26.0 0.5 3.6 7.3 0.0 4.1 3 1 1 4 4 4 3 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CCM06928.1 - 7.8e-05 20.9 7.9 0.086 10.9 2.5 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Gmad1 PF10647.4 CCM06928.1 - 0.0011 18.3 7.2 0.0067 15.8 5.0 2.0 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain FAM72 PF14976.1 CCM06930.1 - 9.7e-11 41.7 1.4 5.8e-09 35.9 0.7 2.3 2 0 0 2 2 2 2 FAM72 protein Yippee-Mis18 PF03226.9 CCM06930.1 - 0.5 10.4 7.3 4.3 7.4 5.1 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Metallophos PF00149.23 CCM06931.1 - 7.8e-14 51.5 0.3 1.3e-13 50.8 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase p450 PF00067.17 CCM06932.1 - 2.4e-46 158.2 0.1 5.2e-46 157.1 0.1 1.5 2 0 0 2 2 2 1 Cytochrome P450 PRA1 PF03208.14 CCM06935.1 - 4.9 6.4 10.7 0.16 11.2 0.9 2.2 2 0 0 2 2 2 0 PRA1 family protein DUF1049 PF06305.6 CCM06938.1 - 0.055 12.9 0.6 0.055 12.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF4131 PF13567.1 CCM06938.1 - 0.14 11.5 2.5 1.7 8.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) VirB8 PF04335.8 CCM06938.1 - 0.62 9.6 3.7 7.1 6.1 0.1 2.2 2 0 0 2 2 2 0 VirB8 protein DUF972 PF06156.8 CCM06941.1 - 0.011 16.0 1.8 0.016 15.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) PA-IIL PF07472.6 CCM06941.1 - 0.062 13.5 1.0 5.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) IRF PF00605.12 CCM06941.1 - 0.11 12.3 0.2 0.37 10.5 0.0 1.9 2 1 0 2 2 2 0 Interferon regulatory factor transcription factor Acetyltransf_11 PF13720.1 CCM06941.1 - 0.18 12.0 1.1 13 6.1 0.0 2.8 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 RNase_H PF00075.19 CCM06941.1 - 0.32 11.3 2.2 0.48 10.7 1.4 1.5 1 1 0 1 1 1 0 RNase H IncA PF04156.9 CCM06941.1 - 0.35 10.4 5.7 27 4.2 3.9 2.2 1 1 0 2 2 2 0 IncA protein MRP-S33 PF08293.6 CCM06941.1 - 0.55 10.2 3.6 5.6 7.0 0.1 3.2 4 0 0 4 4 4 0 Mitochondrial ribosomal subunit S27 KaiB PF07689.7 CCM06946.1 - 0.018 14.4 0.1 0.04 13.3 0.1 1.6 1 0 0 1 1 1 0 KaiB domain Retrotrans_gag PF03732.12 CCM06947.1 - 0.067 13.2 0.2 0.65 10.1 0.0 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.1 CCM06951.1 - 2.1e-08 34.5 0.0 3.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CCM06951.1 - 0.00013 21.5 0.2 0.0002 20.9 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Drf_GBD PF06371.8 CCM06951.1 - 0.011 15.0 0.7 0.019 14.3 0.5 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF4588 PF15251.1 CCM06953.1 - 7.4 6.4 17.1 89 2.9 11.9 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) HTH_Tnp_Tc5 PF03221.11 CCM06954.1 - 3.6e-10 39.5 0.1 8.2e-10 38.3 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain F-box-like PF12937.2 CCM06959.1 - 0.00034 20.2 0.0 0.00092 18.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCM06959.1 - 0.024 14.2 0.6 0.44 10.2 0.1 3.2 2 1 0 2 2 2 0 F-box domain VirB3 PF05101.8 CCM06962.1 - 0.21 11.6 7.8 0.54 10.2 0.1 2.1 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF2189 PF09955.4 CCM06962.1 - 0.34 10.8 8.8 0.78 9.6 1.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) Amnionless PF14828.1 CCM06962.1 - 1.3 7.3 3.2 0.41 9.0 0.3 1.5 1 1 1 2 2 2 0 Amnionless DUF4131 PF13567.1 CCM06962.1 - 1.4 8.2 8.9 3.4 7.0 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DRMBL PF07522.9 CCM06966.1 - 7.4e-30 103.2 0.0 1.8e-29 101.9 0.0 1.7 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CCM06966.1 - 8.1e-11 41.8 0.0 2.1e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FtsK_SpoIIIE PF01580.13 CCM06967.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family B12-binding PF02310.14 CCM06967.1 - 0.038 13.8 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain Peptidase_S10 PF00450.17 CCM06968.1 - 1.4e-08 34.3 0.0 2.8e-08 33.3 0.0 1.4 2 0 0 2 2 2 1 Serine carboxypeptidase RIIa PF02197.12 CCM06968.1 - 0.02 14.2 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Peptidase_S10 PF00450.17 CCM06969.1 - 7.4e-47 160.4 1.8 1.9e-46 159.1 1.3 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase DUF1049 PF06305.6 CCM06971.1 - 0.12 11.8 0.4 0.12 11.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ABC2_membrane_3 PF12698.2 CCM06971.1 - 0.93 8.4 6.0 1.5 7.7 4.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein CoA_binding_3 PF13727.1 CCM06971.1 - 1.9 8.2 5.1 9.7 5.9 1.9 2.1 2 0 0 2 2 2 0 CoA-binding domain PRA1 PF03208.14 CCM06971.1 - 3.3 7.0 11.4 6 6.1 7.8 1.5 1 1 0 1 1 1 0 PRA1 family protein AA_permease_C PF13906.1 CCM06971.1 - 5.3 6.9 10.1 0.41 10.5 2.8 2.2 2 0 0 2 2 2 0 C-terminus of AA_permease RVT_1 PF00078.22 CCM06980.1 - 4.9e-17 62.0 0.1 7.1e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YIF1 PF03878.10 CCM06985.1 - 5e-67 225.5 0.3 7e-67 225.0 0.2 1.1 1 0 0 1 1 1 1 YIF1 Ribosomal_L38e PF01781.13 CCM06985.1 - 2.6e-28 97.5 0.6 3.8e-28 97.0 0.4 1.3 1 0 0 1 1 1 1 Ribosomal L38e protein family Yip1 PF04893.12 CCM06985.1 - 5.1e-06 26.0 0.6 7.9e-06 25.4 0.4 1.2 1 0 0 1 1 1 1 Yip1 domain CMAS PF02353.15 CCM06986.1 - 9.5e-64 215.1 0.0 1.2e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CCM06986.1 - 8.3e-13 48.3 0.0 5.3e-12 45.7 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCM06986.1 - 1.4e-07 31.8 0.1 1.4e-06 28.7 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCM06986.1 - 5.6e-07 30.1 0.0 3.8e-06 27.4 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCM06986.1 - 8.8e-06 26.1 0.0 2.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCM06986.1 - 8.4e-05 22.8 0.1 0.00034 20.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 CCM06986.1 - 0.00085 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CCM06986.1 - 0.0019 18.2 0.0 0.0075 16.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CCM06986.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CCM06986.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 CCM06986.1 - 0.043 13.3 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Herpes_heli_pri PF05774.6 CCM06986.1 - 0.055 13.4 0.5 0.098 12.6 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component RCC1 PF00415.13 CCM06989.1 - 1.1e-32 111.9 9.4 1.3e-07 31.6 1.2 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCM06989.1 - 1.8e-08 33.8 31.3 0.005 16.4 0.8 6.9 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Nucleoporin_FG PF13634.1 CCM06990.1 - 2.5e-05 24.4 16.4 4.5e-05 23.6 11.3 1.4 1 0 0 1 1 1 1 Nucleoporin FG repeat region HMG_CoA_synt_C PF08540.5 CCM06991.1 - 3.3e-88 295.8 0.2 4.5e-88 295.3 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 CCM06991.1 - 2.6e-84 281.0 0.2 5.1e-84 280.1 0.1 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.5 CCM06991.1 - 0.00053 19.9 0.0 0.048 13.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal F-box-like PF12937.2 CCM06992.1 - 7e-09 35.2 2.2 1.2e-08 34.5 0.6 2.2 2 0 0 2 2 2 1 F-box-like BTB PF00651.26 CCM06993.1 - 5.3e-11 42.4 0.9 4.2e-07 29.9 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain Skp1_POZ PF03931.10 CCM06993.1 - 0.017 15.1 0.5 5.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Carb_kinase PF01256.12 CCM06994.1 - 1.1e-49 168.8 0.0 1.7e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CCM06994.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DDE_3 PF13358.1 CCM06997.1 - 4.7e-14 52.3 0.0 6.2e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4501 PF14946.1 CCM07002.1 - 2.2e-05 24.0 0.7 0.076 12.4 0.1 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4501) 2TM PF13239.1 CCM07002.1 - 0.0018 18.3 2.8 0.25 11.4 0.1 2.1 2 0 0 2 2 2 2 2TM domain DUF2244 PF10003.4 CCM07002.1 - 0.0051 16.1 6.4 0.11 11.8 0.4 2.1 2 0 0 2 2 2 2 Integral membrane protein (DUF2244) DUF3366 PF11846.3 CCM07002.1 - 0.029 14.2 3.2 0.51 10.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) DUF2803 PF10972.3 CCM07002.1 - 0.086 12.3 0.4 2.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2803) DUF2189 PF09955.4 CCM07002.1 - 0.49 10.3 11.6 0.75 9.7 1.2 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) RCR PF12273.3 CCM07002.1 - 0.52 10.8 2.7 13 6.3 0.3 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red PRA1 PF03208.14 CCM07002.1 - 0.54 9.5 8.5 3.1 7.1 0.5 2.0 2 0 0 2 2 2 0 PRA1 family protein EI24 PF07264.6 CCM07002.1 - 0.78 9.1 16.1 10 5.4 11.1 1.9 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF3753 PF12575.3 CCM07002.1 - 1.3 8.8 15.9 1.5 8.6 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Nitrate_red_gam PF02665.9 CCM07002.1 - 1.8 7.8 9.8 2.5 7.3 1.3 2.1 2 0 0 2 2 2 0 Nitrate reductase gamma subunit DUF2182 PF09948.4 CCM07002.1 - 2.5 7.9 6.1 9.8 6.0 0.2 2.1 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) PgaD PF13994.1 CCM07002.1 - 3.3 7.1 8.6 3.8 6.9 0.5 2.1 2 0 0 2 2 2 0 PgaD-like protein DUF1218 PF06749.7 CCM07002.1 - 3.7 8.0 9.2 6.2 7.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2975 PF11188.3 CCM07002.1 - 5.7 6.6 13.5 0.78 9.4 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) BatA PF07584.6 CCM07002.1 - 7.6 6.8 16.1 6 7.1 1.5 2.6 2 1 0 2 2 2 0 Aerotolerance regulator N-terminal ATP-synt_8 PF00895.15 CCM07002.1 - 8 6.7 14.6 5.1 7.3 2.2 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 DUF912 PF06024.7 CCM07002.1 - 9 6.4 6.5 4.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tetraspannin PF00335.15 CCM07002.1 - 9.2 5.4 9.4 9.5 5.4 1.1 2.0 2 0 0 2 2 2 0 Tetraspanin family DUF4449 PF14613.1 CCM07009.1 - 3.2e-24 85.7 0.1 3.2e-24 85.7 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Abhydrolase_3 PF07859.8 CCM07010.1 - 7e-25 87.8 0.0 9.4e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCM07010.1 - 3.4e-09 35.8 0.0 5.3e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 CCM07010.1 - 0.00023 21.1 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM07010.1 - 0.059 13.1 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-CCHC PF00098.18 CCM07016.1 - 1.6e-06 27.7 2.3 2.9e-06 26.9 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 CCM07016.1 - 5.1e-05 23.1 1.1 9e-05 22.3 0.8 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.1 CCM07016.1 - 0.0073 15.7 3.3 0.028 13.8 2.0 2.0 1 1 1 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.1 CCM07016.1 - 0.023 14.3 0.4 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 CCM07016.1 - 0.045 13.4 0.7 0.08 12.6 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4501 PF14946.1 CCM07018.1 - 0.052 13.0 0.1 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) DUF4233 PF14017.1 CCM07019.1 - 2.8 7.9 9.1 1.9 8.4 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) Chromo PF00385.19 CCM07020.1 - 9.6e-10 37.9 1.2 3e-09 36.3 0.1 2.2 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF605 PF04652.11 CCM07024.1 - 1 8.6 6.4 1.3 8.3 4.4 1.1 1 0 0 1 1 1 0 Vta1 like zf-CCHC PF00098.18 CCM07032.1 - 7.9e-05 22.3 3.4 0.00014 21.6 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 CCM07032.1 - 0.00066 19.5 0.6 0.0015 18.3 0.4 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 CCM07032.1 - 0.14 11.7 0.4 0.24 10.9 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCM07032.1 - 0.16 11.6 0.8 0.34 10.6 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Miro PF08477.8 CCM07034.1 - 0.00023 21.6 0.0 0.00044 20.7 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCM07034.1 - 0.0004 20.3 0.0 0.00054 19.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 CCM07034.1 - 0.00067 18.9 0.0 0.00082 18.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 CCM07034.1 - 0.0014 17.8 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCM07034.1 - 0.0015 19.3 0.2 0.0034 18.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CCM07034.1 - 0.0061 15.6 0.0 0.0061 15.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 CCM07034.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CCM07034.1 - 0.032 13.9 0.1 0.064 12.9 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase G-alpha PF00503.15 CCM07034.1 - 0.039 12.6 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 CCM07034.1 - 0.04 14.2 0.1 0.051 13.8 0.0 1.2 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 CCM07034.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.13 CCM07034.1 - 0.095 11.9 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 CCM07034.1 - 0.1 11.6 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.4 CCM07034.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 CCM07034.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 CCM07034.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.21 CCM07036.1 - 5.2e-17 61.6 0.0 1.4e-16 60.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCM07036.1 - 1.7e-06 28.9 0.0 1.6e-05 25.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 CCM07036.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain SIS_2 PF13580.1 CCM07036.1 - 0.05 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 SIS domain DUF2855 PF11017.3 CCM07036.1 - 0.086 11.9 0.1 0.32 10.1 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2855) ETX_MTX2 PF03318.8 CCM07037.1 - 6.7e-12 45.4 4.4 1.1e-11 44.8 2.4 1.6 1 1 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.15 CCM07037.1 - 1.9e-06 27.0 1.2 2.5e-06 26.6 0.8 1.1 1 0 0 1 1 1 1 Aerolysin toxin Fascin PF06268.8 CCM07037.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Fascin domain Binary_toxB PF03495.9 CCM07037.1 - 0.017 13.7 5.4 0.04 12.5 3.7 1.6 1 1 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA AIG1 PF04548.11 CCM07038.1 - 2.4e-09 36.6 0.2 9.4e-09 34.6 0.0 2.1 1 1 1 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 CCM07038.1 - 8.1e-06 25.7 2.8 4e-05 23.5 0.2 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.13 CCM07038.1 - 0.00017 20.7 0.2 0.00017 20.7 0.1 2.1 2 0 0 2 2 2 1 Septin FtsK_SpoIIIE PF01580.13 CCM07038.1 - 0.00049 19.6 1.1 0.0011 18.4 0.0 2.1 3 0 0 3 3 2 1 FtsK/SpoIIIE family MobB PF03205.9 CCM07038.1 - 0.00053 19.6 1.7 0.0012 18.5 0.1 2.5 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CCM07038.1 - 0.00062 18.9 0.4 0.00062 18.9 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 T2SE PF00437.15 CCM07038.1 - 0.0013 17.6 0.3 0.0048 15.8 0.2 1.9 1 0 0 1 1 1 1 Type II/IV secretion system protein GTP_EFTU PF00009.22 CCM07038.1 - 0.0014 18.0 4.6 0.0082 15.5 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 CCM07038.1 - 0.0034 17.0 0.1 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CCM07038.1 - 0.0035 17.7 18.7 0.53 10.5 13.0 2.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCM07038.1 - 0.0041 16.2 1.7 0.049 12.7 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 CCM07038.1 - 0.0048 16.6 0.1 0.025 14.2 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CCM07038.1 - 0.0061 16.6 1.6 0.052 13.6 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.1 CCM07038.1 - 0.007 15.8 0.1 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CCM07038.1 - 0.0073 16.6 0.1 0.0073 16.6 0.1 2.9 4 1 0 4 4 3 1 ABC transporter AAA_16 PF13191.1 CCM07038.1 - 0.0077 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain UPF0122 PF04297.9 CCM07038.1 - 0.0096 15.9 0.9 0.0096 15.9 0.6 2.9 2 1 1 3 3 3 1 Putative helix-turn-helix protein, YlxM / p13 like AAA PF00004.24 CCM07038.1 - 0.017 15.3 1.0 0.056 13.6 0.0 2.5 2 1 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCM07038.1 - 0.024 14.1 0.0 0.065 12.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 CCM07038.1 - 0.028 14.7 0.1 0.028 14.7 0.0 3.4 5 0 0 5 5 4 0 AAA domain NACHT PF05729.7 CCM07038.1 - 0.028 14.0 0.1 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 CCM07038.1 - 0.03 13.7 0.1 0.095 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CCM07038.1 - 0.032 13.7 1.1 0.088 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CCM07038.1 - 0.034 14.6 2.5 0.12 12.8 0.0 2.8 2 1 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 CCM07038.1 - 0.088 13.6 0.0 0.088 13.6 0.0 2.6 4 0 0 4 4 2 0 AAA domain DUF4094 PF13334.1 CCM07038.1 - 2.9 8.3 6.1 2.2 8.7 0.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) CM2 PF03021.9 CCM07043.1 - 0.041 13.4 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M2 protein p450 PF00067.17 CCM07044.1 - 4.2e-51 173.9 0.0 4.4e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM07045.1 - 5.9e-57 193.2 0.0 6.7e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 CCM07046.1 - 1.8e-27 96.1 0.0 6.7e-27 94.2 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 CCM07046.1 - 1.1e-05 26.0 0.0 0.00023 21.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MarR_2 PF12802.2 CCM07046.1 - 7.2e-05 22.3 0.0 0.00058 19.4 0.0 2.2 2 0 0 2 2 2 1 MarR family RPA_C PF08784.6 CCM07046.1 - 0.0016 18.8 0.0 0.0032 17.8 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal Methyltransf_23 PF13489.1 CCM07046.1 - 0.0023 17.6 0.0 0.36 10.5 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCM07046.1 - 0.0038 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain HTH_IclR PF09339.5 CCM07046.1 - 0.019 14.5 0.1 0.075 12.6 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Methyltransf_16 PF10294.4 CCM07046.1 - 0.029 13.8 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MarR PF01047.17 CCM07046.1 - 0.03 14.0 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 MarR family Methyltransf_4 PF02390.12 CCM07046.1 - 0.053 12.5 0.0 0.13 11.3 0.0 1.6 1 1 1 2 2 2 0 Putative methyltransferase Dimerisation PF08100.6 CCM07046.1 - 0.095 12.5 0.0 0.32 10.8 0.0 2.0 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_31 PF13847.1 CCM07046.1 - 0.095 12.2 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Rrf2 PF02082.15 CCM07046.1 - 0.096 12.8 0.0 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator HTH_28 PF13518.1 CCM07046.1 - 0.11 12.5 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain ATP-synt_DE PF00401.15 CCM07050.1 - 0.097 12.5 2.3 0.15 11.9 1.6 1.3 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain SH PF01445.12 CCM07050.1 - 0.11 12.1 0.6 0.18 11.5 0.4 1.3 1 0 0 1 1 1 0 Viral small hydrophobic protein Fungal_trans PF04082.13 CCM07053.1 - 2.1e-15 56.2 0.1 3.2e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain cobW PF02492.14 CCM07054.1 - 1.6e-38 131.9 0.0 2.4e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DnaJ PF00226.26 CCM07054.1 - 4.6e-15 55.1 0.1 1.1e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain MobB PF03205.9 CCM07054.1 - 0.005 16.5 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.9 CCM07054.1 - 0.073 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain DUF572 PF04502.8 CCM07055.1 - 6.2e-58 196.5 0.3 8.4e-58 196.1 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Ribosomal_S10 PF00338.17 CCM07056.1 - 1.2e-30 105.1 0.5 1.4e-30 104.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Exo_endo_phos PF03372.18 CCM07057.1 - 1.2e-13 51.5 1.2 5.6e-10 39.5 0.1 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Voldacs PF03517.8 CCM07058.1 - 1.9e-28 98.9 0.2 2.7e-28 98.5 0.2 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling SH3_1 PF00018.23 CCM07059.1 - 7.6e-13 47.6 0.2 1.1e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCM07059.1 - 2e-11 43.3 0.1 2.8e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCM07059.1 - 5.8e-11 41.7 0.0 8.8e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain RVT_1 PF00078.22 CCM07062.1 - 1.7e-20 73.2 0.1 3.8e-20 72.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2525 PF10733.4 CCM07064.1 - 0.011 15.5 0.2 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) DUF4035 PF13227.1 CCM07067.1 - 0.08 12.3 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) DUF4501 PF14946.1 CCM07069.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) DUF3329 PF11808.3 CCM07069.1 - 7.5 6.7 7.5 3 7.9 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) CD99L2 PF12301.3 CCM07072.1 - 0.11 12.1 8.1 0.15 11.7 5.6 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 zf-CCCH PF00642.19 CCM07076.1 - 1.3e-09 37.4 25.4 0.0001 21.9 1.7 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cnd2 PF05786.9 CCM07077.1 - 9.9e-147 490.4 3.5 1.5e-145 486.5 2.4 2.1 1 1 0 1 1 1 1 Condensin complex subunit 2 SpoVIF PF14069.1 CCM07078.1 - 0.018 14.7 1.6 0.03 14.0 1.1 1.3 1 0 0 1 1 1 0 Stage VI sporulation protein F Sugar_tr PF00083.19 CCM07079.1 - 4.2e-124 414.5 26.0 4.7e-124 414.3 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCM07079.1 - 4.2e-16 58.5 44.4 5.1e-16 58.3 27.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 CCM07079.1 - 0.19 11.7 1.9 0.53 10.2 0.1 2.7 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Ecl1 PF12855.2 CCM07081.1 - 0.0034 16.6 0.6 0.0055 15.9 0.4 1.3 1 0 0 1 1 1 1 Life-span regulatory factor RVT_1 PF00078.22 CCM07082.1 - 4.2e-19 68.7 0.0 1.1e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CCM07082.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.22 CCM07084.1 - 0.036 13.4 0.0 3.3 7.0 0.0 2.1 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Nop10p PF04135.7 CCM07085.1 - 0.044 13.5 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family NUDIX PF00293.23 CCM07088.1 - 2.5e-10 40.1 0.0 4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GST_N PF02798.15 CCM07089.1 - 5.1e-15 55.4 0.0 1.2e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCM07089.1 - 1.8e-14 53.7 0.0 2.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCM07089.1 - 1.6e-13 50.4 0.0 5.2e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCM07089.1 - 2.8e-11 43.2 0.0 3.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCM07089.1 - 7e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCM07089.1 - 0.015 15.7 0.1 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.2 CCM07091.1 - 4.3e-20 72.5 2.0 6.9e-20 71.9 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCM07091.1 - 5.8e-11 42.3 0.1 8.3e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCM07091.1 - 4.5e-09 36.2 0.2 6.7e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCM07091.1 - 1.3e-05 24.9 0.0 2.6e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 CCM07091.1 - 0.00027 20.3 0.1 0.0039 16.4 0.1 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family p450 PF00067.17 CCM07093.1 - 2.1e-28 99.0 0.0 2.6e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pex24p PF06398.6 CCM07095.1 - 1.3e-07 30.8 4.6 1.8e-07 30.3 3.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HSCB_C PF07743.8 CCM07096.1 - 2.7e-12 46.9 2.6 2.7e-12 46.9 1.8 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CCM07096.1 - 1.8e-08 33.9 0.0 3.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain FCD PF07729.7 CCM07096.1 - 0.0079 16.5 3.1 0.015 15.6 0.6 2.1 2 0 0 2 2 2 1 FCD domain DUF349 PF03993.7 CCM07096.1 - 0.053 13.6 1.8 0.14 12.3 0.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) HA2 PF04408.18 CCM07097.1 - 4.3e-19 68.4 0.1 1.2e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCM07097.1 - 9.1e-12 44.6 0.1 2.1e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 CCM07097.1 - 2.4e-10 40.8 0.1 6.6e-05 23.4 0.0 2.9 3 0 0 3 3 3 2 Double-stranded RNA binding motif DEAD PF00270.24 CCM07097.1 - 2.6e-06 27.0 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CCM07097.1 - 6.3e-06 25.9 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AGTRAP PF06396.6 CCM07098.1 - 0.00039 20.1 1.6 0.00098 18.8 1.1 1.6 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) TMEM169 PF15052.1 CCM07098.1 - 0.042 13.7 0.5 0.057 13.3 0.4 1.2 1 0 0 1 1 1 0 TMEM169 protein family Transaldolase PF00923.14 CCM07099.1 - 3.2e-34 118.3 1.2 4.2e-34 117.9 0.8 1.2 1 0 0 1 1 1 1 Transaldolase DNA_pol_B PF00136.16 CCM07100.1 - 1.2e-92 311.1 0.0 1.6e-92 310.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCM07100.1 - 5.1e-14 51.8 0.0 9.9e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCM07100.1 - 4e-13 49.1 2.6 7.5e-13 48.2 1.8 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CCM07100.1 - 0.15 10.7 0.1 0.23 10.0 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral MFS_1 PF07690.11 CCM07102.1 - 0.029 13.1 0.5 0.029 13.0 0.4 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Fun_ATP-synt_8 PF05933.8 CCM07102.1 - 0.076 13.0 4.2 0.13 12.2 2.9 1.4 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) ATP-synt_8 PF00895.15 CCM07102.1 - 0.45 10.7 11.2 0.041 14.1 4.1 1.9 2 0 0 2 2 2 0 ATP synthase protein 8 TarH PF02203.10 CCM07102.1 - 7.7 6.3 5.5 10 5.9 3.8 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue Ribosomal_L39 PF00832.15 CCM07104.1 - 0.083 12.3 0.3 0.094 12.1 0.2 1.1 1 0 0 1 1 1 0 Ribosomal L39 protein RhaA PF06134.6 CCM07110.1 - 0.015 14.2 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) RVT_1 PF00078.22 CCM07112.1 - 9.1e-12 44.7 0.0 1.4e-11 44.1 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CCM07113.1 - 6.3e-09 35.3 0.6 1.7e-08 34.0 0.0 2.0 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Virulence_fact PF13769.1 CCM07116.1 - 0.042 13.7 0.6 0.15 11.9 0.4 1.8 1 1 0 1 1 1 0 Virulence factor Ribosomal_S13_N PF08069.7 CCM07117.1 - 4.9 7.0 6.9 1.4 8.8 0.1 2.5 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain RVT_1 PF00078.22 CCM07119.1 - 5.1e-11 42.3 0.0 1.1e-07 31.3 0.0 2.7 1 1 3 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCM07120.1 - 0.043 13.9 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain VirB3 PF05101.8 CCM07121.1 - 0.012 15.5 2.0 0.9 9.5 0.0 2.1 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein ABC2_membrane_3 PF12698.2 CCM07121.1 - 0.12 11.3 4.4 0.17 10.8 3.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein LAT PF15234.1 CCM07121.1 - 1.5 8.2 3.3 0.51 9.7 0.3 1.6 1 1 1 2 2 2 0 Linker for activation of T-cells ATP-synt_8 PF00895.15 CCM07121.1 - 6 7.1 13.4 0.2 11.8 4.3 2.0 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3377 PF11857.3 CCM07122.1 - 0.13 11.9 0.3 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) ThiF PF00899.16 CCM07128.1 - 8e-32 109.9 0.0 2.3e-31 108.4 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 CCM07128.1 - 0.025 14.6 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MR_MLE_C PF13378.1 CCM07130.1 - 0.073 13.0 0.5 0.52 10.3 0.1 2.5 2 1 0 2 2 2 0 Enolase C-terminal domain-like Chromo PF00385.19 CCM07132.1 - 2.9e-09 36.4 1.7 9.6e-09 34.7 0.0 2.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CCM07132.1 - 0.00023 21.2 0.0 0.00048 20.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain eIF3g PF12353.3 CCM07133.1 - 0.0011 18.9 1.5 0.0029 17.5 1.1 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.18 CCM07133.1 - 0.0022 17.8 1.9 0.0057 16.5 1.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 CCM07133.1 - 0.046 13.1 4.2 0.14 11.6 2.6 2.0 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger Cript PF10235.4 CCM07133.1 - 2 8.8 6.2 1.2 9.4 1.4 2.5 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Cpn10 PF00166.16 CCM07136.1 - 7.8e-25 86.6 0.0 1.5e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit zf-MYND PF01753.13 CCM07136.1 - 9.9e-08 31.7 12.8 1.8e-07 30.9 8.9 1.4 1 0 0 1 1 1 1 MYND finger Pho88 PF10032.4 CCM07137.1 - 1.7e-73 245.9 0.6 1.9e-73 245.8 0.4 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Retrotrans_gag PF03732.12 CCM07139.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein AMNp_N PF10423.4 CCM07140.1 - 0.029 13.9 1.8 5.3 6.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus Ibs_toxin PF13956.1 CCM07142.1 - 0.078 12.7 2.3 0.078 12.7 1.6 1.6 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system SUR7 PF06687.7 CCM07142.1 - 0.088 12.3 0.2 0.082 12.4 0.1 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF3328 PF11807.3 CCM07142.1 - 0.11 12.2 0.9 0.12 12.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) CAP_N PF01213.14 CCM07142.1 - 0.11 11.7 1.0 0.12 11.6 0.7 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SUR7 PF06687.7 CCM07153.1 - 0.015 14.8 4.0 0.019 14.5 2.8 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF3329 PF11808.3 CCM07153.1 - 0.27 11.3 8.2 1.8 8.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) VirB3 PF05101.8 CCM07153.1 - 1.2 9.1 9.8 0.3 11.1 0.3 2.1 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein RVT_1 PF00078.22 CCM07154.1 - 0.0035 16.7 0.0 0.0086 15.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RE_ApaLI PF09499.5 CCM07155.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease MPC PF03650.8 CCM07158.1 - 0.0089 15.9 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) FA_desaturase PF00487.19 CCM07159.1 - 2.8e-14 53.1 20.1 2.8e-14 53.1 13.9 2.9 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 CCM07159.1 - 1.4e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) RVT_1 PF00078.22 CCM07168.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Neisseria_TspB PF05616.8 CCM07169.1 - 7.1 4.8 12.3 8.5 4.6 8.5 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ADH_N PF08240.7 CCM07171.1 - 4.8e-12 45.5 0.0 6.6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fe-ADH PF00465.14 CCM07177.1 - 3.7e-54 183.7 1.4 4.9e-54 183.3 1.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CCM07177.1 - 1.8e-33 115.9 0.1 2.2e-33 115.5 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 CCM07177.1 - 0.00046 19.1 1.7 0.046 12.6 0.0 2.7 2 1 0 2 2 2 2 3-dehydroquinate synthase Pkinase PF00069.20 CCM07178.1 - 1.4e-60 204.6 0.0 1.3e-59 201.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCM07178.1 - 8.2e-28 97.1 0.0 5.4e-15 55.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 CCM07178.1 - 0.00023 21.6 6.1 0.00023 21.6 4.2 3.5 3 1 0 3 3 3 1 Protein kinase C terminal domain PX PF00787.19 CCM07178.1 - 0.0014 18.3 0.0 0.0088 15.8 0.0 2.2 1 1 0 1 1 1 1 PX domain Kdo PF06293.9 CCM07178.1 - 0.0017 17.4 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCM07178.1 - 0.0092 14.9 0.0 0.81 8.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like GRAM PF02893.15 CCM07179.1 - 7e-15 54.3 0.0 1.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Asp PF00026.18 CCM07181.1 - 4.9e-45 154.1 8.9 6.6e-44 150.4 6.2 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCM07181.1 - 1.2e-05 25.2 2.5 0.00027 20.9 1.2 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCM07181.1 - 0.0039 17.6 1.4 0.064 13.7 0.2 2.7 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 CCM07181.1 - 0.078 12.5 0.1 0.25 10.8 0.0 1.9 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Methyltransf_2 PF00891.13 CCM07183.1 - 1.4e-15 57.1 0.1 7.5e-08 31.8 0.0 3.1 3 0 0 3 3 3 2 O-methyltransferase Auxin_BP PF02041.11 CCM07185.1 - 0.031 13.7 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein p450 PF00067.17 CCM07188.1 - 1e-17 63.8 0.0 1.3e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CCM07189.1 - 4.5e-48 163.9 0.0 1.8e-25 89.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 CCM07190.1 - 1.5e-69 234.7 0.0 2.4e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 PMP1_2 PF08114.6 CCM07190.1 - 0.045 13.2 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 ATPase proteolipid family p450 PF00067.17 CCM07191.1 - 6.4e-78 262.3 0.0 1.3e-77 261.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 G-alpha PF00503.15 CCM07192.1 - 3.2e-124 414.5 2.1 4e-124 414.2 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCM07192.1 - 1.3e-14 53.8 0.1 9.4e-09 34.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCM07192.1 - 0.0014 17.7 0.1 0.51 9.4 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CCM07192.1 - 0.026 15.0 0.0 0.74 10.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 CCM07192.1 - 0.048 13.1 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CCM07192.1 - 0.076 12.4 0.0 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Chromo PF00385.19 CCM07196.1 - 1.9e-08 33.8 0.8 4e-08 32.8 0.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4404 PF14357.1 CCM07196.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) dUTPase PF00692.14 CCM07196.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 dUTPase DUF4397 PF14344.1 CCM07198.1 - 0.16 12.2 0.7 54 4.1 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4397) CDRN PF05174.7 CCM07199.1 - 0.1 12.0 0.2 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus 2TM PF13239.1 CCM07204.1 - 0.15 12.1 0.3 0.23 11.5 0.2 1.2 1 0 0 1 1 1 0 2TM domain Chromo PF00385.19 CCM07205.1 - 1.8e-11 43.5 0.2 4.1e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DNA_pol3_delta PF06144.8 CCM07205.1 - 0.089 12.2 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Retrotrans_gag PF03732.12 CCM07206.1 - 0.011 15.7 2.4 0.027 14.5 0.0 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein Bacillus_HBL PF05791.6 CCM07206.1 - 0.025 13.9 0.2 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Tetraspannin PF00335.15 CCM07211.1 - 0.011 15.0 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family LAT PF15234.1 CCM07211.1 - 0.014 14.8 1.5 0.014 14.8 1.1 1.0 1 0 0 1 1 1 0 Linker for activation of T-cells DUF3328 PF11807.3 CCM07211.1 - 0.061 12.9 1.8 0.088 12.4 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) ATP-synt_8 PF00895.15 CCM07211.1 - 5.5 7.2 10.5 0.83 9.9 2.3 2.4 2 1 0 2 2 2 0 ATP synthase protein 8 DUF2244 PF10003.4 CCM07212.1 - 0.098 12.0 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF3328 PF11807.3 CCM07212.1 - 0.11 12.2 0.8 0.13 11.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) O-antigen_lig PF13425.1 CCM07212.1 - 0.26 11.2 4.1 0.3 11.0 2.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2393 PF09624.5 CCM07212.1 - 0.31 10.5 1.2 0.38 10.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Fun_ATP-synt_8 PF05933.8 CCM07212.1 - 5.5 7.1 6.9 3 7.9 3.5 1.5 1 1 1 2 2 2 0 Fungal ATP synthase protein 8 (A6L) DUF3432 PF11914.3 CCM07216.1 - 0.13 12.2 5.4 0.23 11.4 3.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Metallothio_11 PF02066.10 CCM07216.1 - 5.1 7.0 7.1 0.55 10.1 0.4 2.1 2 0 0 2 2 2 0 Metallothionein family 11 DUF3573 PF12097.3 CCM07218.1 - 0.17 10.4 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SDA1 PF05285.7 CCM07219.1 - 0.8 8.9 6.8 0.97 8.6 4.7 1.1 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 CCM07219.1 - 2.7 7.4 9.3 4.2 6.8 6.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF4501 PF14946.1 CCM07221.1 - 0.12 11.7 2.2 0.12 11.9 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) DUF4131 PF13567.1 CCM07221.1 - 0.66 9.3 3.6 0.64 9.4 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2244 PF10003.4 CCM07221.1 - 0.96 8.8 3.7 0.93 8.8 2.6 1.0 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) SdpI PF13630.1 CCM07221.1 - 4.5 7.0 6.6 4.4 7.0 4.6 1.0 1 0 0 1 1 1 0 SdpI/YhfL protein family 2OG-FeII_Oxy_2 PF13532.1 CCM07222.1 - 2.6e-37 128.5 0.0 1.1e-34 120.0 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily ATP12 PF07542.6 CCM07223.1 - 1.1e-40 138.3 0.1 1.7e-40 137.7 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Oligomerisation PF02410.10 CCM07223.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Oligomerisation domain SHR3_chaperone PF08229.6 CCM07224.1 - 6e-26 90.6 0.1 6.7e-25 87.1 0.1 1.9 1 1 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.1 CCM07224.1 - 0.042 14.2 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) RVT_thumb PF06817.9 CCM07226.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 Reverse transcriptase thumb domain RVT_1 PF00078.22 CCM07227.1 - 0.0022 17.4 0.0 0.0044 16.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CCM07227.1 - 0.0083 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 CCM07230.1 - 8.5e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCM07233.1 - 0.0023 17.3 0.0 0.0061 15.9 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADH_N PF08240.7 CCM07239.1 - 4.5e-22 77.8 0.6 8.8e-22 76.9 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_6 PF12697.2 CCM07239.1 - 4.8e-17 62.6 4.7 8e-15 55.3 3.3 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family ADH_zinc_N PF00107.21 CCM07239.1 - 4.5e-15 55.3 0.1 9.6e-15 54.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_5 PF12695.2 CCM07239.1 - 3.7e-09 36.4 0.3 2e-08 34.1 0.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CCM07239.1 - 2.2e-05 24.2 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 CCM07239.1 - 0.00048 19.9 0.1 0.0015 18.3 0.1 1.8 1 0 0 1 1 1 1 Putative lysophospholipase 2-Hacid_dh_C PF02826.14 CCM07239.1 - 0.08 12.0 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.15 CCM07239.1 - 0.11 12.0 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold ELFV_dehydrog PF00208.16 CCM07239.1 - 0.15 11.6 0.1 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RVT_1 PF00078.22 CCM07244.1 - 2e-18 66.5 0.2 6.9e-17 61.5 0.1 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding PF00501.23 CCM07254.1 - 2.9e-36 124.7 0.0 3.8e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCM07254.1 - 2.6e-06 28.2 0.4 5.8e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sybindin PF04099.7 CCM07256.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sybindin-like family TMEM173 PF15009.1 CCM07256.1 - 0.19 10.4 3.6 2.1 7.0 0.3 2.1 2 0 0 2 2 2 0 Transmembrane protein 173 Abhydrolase_3 PF07859.8 CCM07257.1 - 2.5e-23 82.7 0.0 3.5e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCM07257.1 - 3.3e-07 29.2 0.0 5.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF2974 PF11187.3 CCM07257.1 - 0.023 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 CCM07257.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCM07257.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family RVT_1 PF00078.22 CCM07259.1 - 1.2e-17 63.9 0.2 2e-17 63.3 0.1 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Yip1 PF04893.12 CCM07260.1 - 0.0052 16.2 7.3 0.0064 16.0 5.1 1.1 1 0 0 1 1 1 1 Yip1 domain DUF4131 PF13567.1 CCM07260.1 - 0.18 11.1 6.6 0.31 10.4 4.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Neurensin PF14927.1 CCM07260.1 - 0.4 10.0 4.7 0.52 9.6 3.3 1.1 1 0 0 1 1 1 0 Neurensin EXS PF03124.9 CCM07260.1 - 2.3 7.1 7.6 2.5 7.0 5.3 1.1 1 0 0 1 1 1 0 EXS family p450 PF00067.17 CCM07264.1 - 2.3e-32 112.1 0.0 2.7e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S58 PF03576.9 CCM07266.1 - 6.6 5.8 9.4 7.5 5.6 6.5 1.0 1 0 0 1 1 1 0 Peptidase family S58 GATase_2 PF00310.16 CCM07267.1 - 0.078 11.6 0.0 0.086 11.5 0.0 1.0 1 0 0 1 1 1 0 Glutamine amidotransferases class-II FUSC_2 PF13515.1 CCM07268.1 - 0.066 13.1 5.4 0.17 11.8 1.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein-like ABC2_membrane_3 PF12698.2 CCM07268.1 - 1.2 8.0 7.5 1.7 7.6 5.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SUR7 PF06687.7 CCM07268.1 - 1.6 8.2 8.4 2 7.9 5.8 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF3377 PF11857.3 CCM07268.1 - 1.8 8.2 3.8 5.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF4131 PF13567.1 CCM07268.1 - 7.8 5.8 10.5 20 4.5 7.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131)