# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Sec10 PF07393.6 AET37261.1 - 7.5e-41 140.1 1.9 8e-41 140.0 1.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 NAD_Gly3P_dh_C PF07479.9 AET37261.1 - 0.1 12.2 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Homeobox_KN PF05920.6 AET37262.1 - 4.8e-07 29.3 0.5 1.1e-06 28.1 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 AET37262.1 - 3.7e-06 26.4 0.4 1.1e-05 24.9 0.2 1.8 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 AET37262.1 - 0.0004 19.3 0.0 0.00076 18.4 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 AET37262.1 - 0.03 14.3 0.0 0.077 13.1 0.0 1.7 1 1 0 1 1 1 0 Helicase associated domain HTH_28 PF13518.1 AET37262.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1160 PF06648.6 AET37262.1 - 0.12 12.1 1.4 0.31 10.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) MAT_Alpha1 PF04769.7 AET37263.1 - 3.5e-10 39.5 5.5 9.8e-10 38.0 0.9 2.5 1 1 0 1 1 1 1 Mating-type protein MAT alpha 1 SUI1 PF01253.17 AET37264.1 - 7.9e-29 99.3 0.4 9.5e-29 99.0 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.3 AET37264.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Cas_Csa5 PF09702.5 AET37264.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) PALP PF00291.20 AET37265.1 - 2.4e-58 197.8 0.0 2.7e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CoA_binding_2 PF13380.1 AET37265.1 - 0.073 13.2 0.0 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 CoA binding domain MRC1 PF09444.5 AET37267.1 - 7e-39 133.4 6.8 7e-39 133.4 4.7 5.6 4 2 2 6 6 6 2 MRC1-like domain KH_1 PF00013.24 AET37268.1 - 0.0089 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 AET37268.1 - 0.049 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 KH domain DUF543 PF04418.7 AET37269.1 - 2.9e-29 100.8 0.3 3.2e-29 100.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Peptidase_M3 PF01432.15 AET37270.1 - 7.7e-148 493.3 0.2 9.8e-148 492.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 AET37270.1 - 0.24 10.7 0.4 0.36 10.1 0.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like HisKA PF00512.20 AET37271.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain 2OG-FeII_Oxy_2 PF13532.1 AET37272.1 - 7.7e-21 74.8 0.1 1e-20 74.3 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2225 PF09986.4 AET37272.1 - 0.018 14.4 0.4 0.029 13.8 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) 2OG-FeII_Oxy PF03171.15 AET37272.1 - 0.057 13.7 0.2 0.35 11.1 0.1 2.4 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Zn_ribbon_recom PF13408.1 AET37272.1 - 0.4 10.9 4.5 1.3 9.3 3.1 1.8 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Tuberculin PF12198.3 AET37273.1 - 0.03 14.2 0.1 0.094 12.6 0.1 1.8 1 0 0 1 1 1 0 Theoretical tuberculin protein Voltage_CLC PF00654.15 AET37274.1 - 3.1e-87 292.8 17.9 3.1e-87 292.8 12.4 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel ATP-synt_8 PF00895.15 AET37274.1 - 0.46 10.7 3.9 0.3 11.3 0.7 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 Sp38 PF07354.7 AET37275.1 - 0.0038 15.9 0.4 0.0063 15.2 0.3 1.3 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) MT-A70 PF05063.9 AET37276.1 - 7.3e-14 51.7 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 MT-A70 CMAS PF02353.15 AET37277.1 - 1.3e-62 211.4 0.2 1.5e-62 211.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 AET37277.1 - 7.9e-12 45.1 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AET37277.1 - 3.8e-09 36.9 0.0 7.9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AET37277.1 - 2.1e-07 31.3 0.0 4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET37277.1 - 2.3e-07 31.4 0.0 4.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET37277.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET37277.1 - 0.00037 20.5 0.0 0.00091 19.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET37277.1 - 0.0029 17.9 0.0 0.0069 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AET37277.1 - 0.0082 16.1 0.1 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 AET37277.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.8 AET37277.1 - 0.038 13.3 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.14 AET37277.1 - 0.098 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spermine_synth PF01564.12 AET37277.1 - 0.15 10.9 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase DUF3381 PF11861.3 AET37278.1 - 2.4e-53 179.9 18.5 2.4e-53 179.9 12.8 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 AET37278.1 - 7.7e-53 179.1 1.3 3.5e-52 177.0 0.1 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase Spb1_C PF07780.7 AET37278.1 - 1.3e-49 168.6 10.4 1.3e-49 168.6 7.2 3.3 3 0 0 3 3 3 1 Spb1 C-terminal domain PIG-X PF08320.7 AET37279.1 - 1.1e-47 162.0 0.5 1.9e-47 161.2 0.3 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 Toxin_4 PF00706.12 AET37280.1 - 0.1 12.7 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Anenome neurotoxin UCR_14kD PF02271.11 AET37281.1 - 1.4e-42 143.6 0.1 1.7e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit ATP_transf PF09830.4 AET37282.1 - 3.9e-17 61.7 0.0 7.4e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 AET37282.1 - 6.8e-05 23.3 0.0 0.00022 21.6 0.0 1.8 1 0 0 1 1 1 1 HIT domain Fumble PF03630.9 AET37283.1 - 8.5e-109 363.5 3.9 2.9e-107 358.4 0.7 2.0 1 1 1 2 2 2 2 Fumble RPAP1_C PF08620.5 AET37284.1 - 4.4e-30 103.3 0.0 9.7e-30 102.2 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 AET37284.1 - 7.2e-17 60.7 0.2 1.8e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal Asp_Glu_race PF01177.17 AET37285.1 - 4.7e-15 56.0 0.0 8e-15 55.3 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF4231 PF14015.1 AET37286.1 - 0.66 9.9 3.3 0.85 9.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Period_C PF12114.3 AET37286.1 - 1.9 8.0 5.1 2 7.9 3.5 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Enamelin PF15362.1 AET37286.1 - 2.6 6.0 4.6 2.9 5.8 3.2 1.0 1 0 0 1 1 1 0 Enamelin CDK2AP PF09806.4 AET37286.1 - 3.1 7.9 7.8 3.4 7.8 5.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein QCR10 PF09796.4 AET37286.1 - 5.9 6.6 8.4 2.5 7.8 2.7 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) ArfGap PF01412.13 AET37287.1 - 7.3e-31 106.3 0.6 3.4e-30 104.2 0.2 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 AET37287.1 - 4.9e-12 45.9 1.5 1.8e-11 44.1 0.2 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 AET37287.1 - 0.01 16.0 0.1 0.035 14.2 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.20 AET37288.1 - 1.1e-68 231.1 0.0 1.5e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37288.1 - 5.1e-48 163.4 0.0 7.5e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET37288.1 - 3.4e-05 22.9 0.0 0.00013 21.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like DUF4404 PF14357.1 AET37288.1 - 0.051 14.0 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Recep_L_domain PF01030.19 AET37289.1 - 4.1e-09 36.3 8.6 0.0029 17.5 0.0 4.3 1 1 4 5 5 5 4 Receptor L domain FGF-BP1 PF06473.7 AET37289.1 - 0.57 9.7 5.3 0.88 9.1 3.7 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) LRR_4 PF12799.2 AET37289.1 - 0.6 9.8 10.9 7.3 6.3 3.1 4.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Zn_clus PF00172.13 AET37290.1 - 6e-05 22.8 6.0 0.00013 21.7 4.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTP_transf_2 PF01467.21 AET37291.1 - 8.6e-08 32.3 0.2 3e-07 30.6 0.2 1.8 1 1 0 1 1 1 1 Cytidylyltransferase HIGH_NTase1 PF05636.6 AET37291.1 - 0.043 12.8 1.3 3.5 6.5 0.1 2.1 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase DUF1620 PF07774.8 AET37292.1 - 1.3e-68 230.4 2.8 1.3e-68 230.4 1.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ PF01011.16 AET37292.1 - 0.0022 17.4 0.0 0.03 13.8 0.0 2.6 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 AET37292.1 - 0.004 16.6 0.0 0.038 13.4 0.0 2.5 2 1 1 3 3 3 1 PQQ-like domain Mgr1 PF08602.5 AET37293.1 - 2.7e-130 434.6 0.0 3.2e-130 434.3 0.0 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit Thioredoxin PF00085.15 AET37294.1 - 7.2e-53 176.6 0.3 6.5e-25 86.8 0.0 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 AET37294.1 - 2.2e-25 89.5 2.3 1.3e-18 67.4 0.2 3.7 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 AET37294.1 - 1.6e-10 41.1 0.9 0.00028 21.0 0.0 3.6 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AET37294.1 - 1.4e-08 34.6 0.0 0.0087 16.0 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 AET37294.1 - 5.6e-06 26.3 0.2 0.044 13.9 0.0 3.6 2 2 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 AET37294.1 - 2.6e-05 23.8 0.1 0.035 13.7 0.0 3.1 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 AET37294.1 - 0.0014 18.2 0.0 0.071 12.6 0.0 2.5 2 0 0 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 AET37294.1 - 0.011 15.2 0.0 6.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.1 AET37294.1 - 0.073 13.0 0.1 13 5.7 0.0 3.2 2 1 1 3 3 3 0 Thioredoxin GRASP55_65 PF04495.9 AET37295.1 - 1.1e-34 119.3 0.0 7.6e-33 113.4 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Hexokinase_2 PF03727.11 AET37296.1 - 9e-87 290.2 0.0 1.2e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 AET37296.1 - 3.1e-69 232.4 0.0 8.7e-69 230.9 0.0 1.7 2 0 0 2 2 2 1 Hexokinase WD40 PF00400.27 AET37297.1 - 3.7e-20 70.9 12.6 6.7e-05 22.6 0.0 7.1 6 1 0 6 6 6 4 WD domain, G-beta repeat BBS2_N PF14781.1 AET37297.1 - 0.00011 21.8 0.6 0.5 9.9 0.1 3.1 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal ATG22 PF11700.3 AET37298.1 - 5.6e-158 526.3 30.1 6.3e-158 526.1 20.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 AET37298.1 - 3.5e-08 32.5 17.4 3.5e-08 32.5 12.1 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily La PF05383.12 AET37299.1 - 2e-18 65.8 0.0 4.4e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 La domain Mre11_DNA_bind PF04152.9 AET37300.1 - 0.065 13.0 0.3 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain Flocculin_t3 PF13928.1 AET37301.1 - 5.4e-13 48.8 58.3 3.5e-06 27.0 4.8 4.7 4 1 0 4 4 4 3 Flocculin type 3 repeat Glutaredoxin PF00462.19 AET37302.1 - 4.4e-16 58.6 0.0 6.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 AET37302.1 - 0.0032 17.6 0.1 0.0052 16.9 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 AET37302.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 AET37302.1 - 0.03 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin CENP_C_N PF15622.1 AET37302.1 - 0.071 12.3 0.1 0.09 12.0 0.1 1.1 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal GAT PF03127.9 AET37303.1 - 3.5e-06 26.9 0.2 3.5e-06 26.9 0.2 2.2 2 1 0 2 2 2 1 GAT domain BAG PF02179.11 AET37303.1 - 0.037 14.1 1.3 2.6 8.2 0.0 3.3 3 0 0 3 3 3 0 BAG domain VHS PF00790.14 AET37303.1 - 0.051 13.2 0.1 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 VHS domain RIH_assoc PF08454.6 AET37303.1 - 0.084 12.5 0.5 6.5 6.4 0.0 3.1 3 1 0 3 3 3 0 RyR and IP3R Homology associated SelR PF01641.13 AET37304.1 - 3.3e-50 168.9 0.1 4e-50 168.6 0.1 1.1 1 0 0 1 1 1 1 SelR domain DUF3252 PF11623.3 AET37304.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3252) Yippee-Mis18 PF03226.9 AET37304.1 - 0.13 12.3 2.6 0.72 9.9 1.8 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly A2L_zn_ribbon PF08792.5 AET37304.1 - 1.6 8.2 6.5 0.49 9.9 0.2 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF3128 PF11326.3 AET37305.1 - 3.5e-28 97.5 0.9 3.9e-28 97.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) CHCH PF06747.8 AET37305.1 - 1.5 8.8 5.0 4.2 7.4 0.3 2.2 2 0 0 2 2 2 0 CHCH domain RA PF00788.18 AET37306.1 - 6.6e-16 58.5 0.1 1.5e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ste50p-SAM PF09235.5 AET37306.1 - 5.3e-14 51.9 1.7 6.1e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Ste50p, sterile alpha motif SAM_2 PF07647.12 AET37306.1 - 0.072 12.9 0.7 3.7 7.4 0.0 2.8 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) RRP7 PF12923.2 AET37307.1 - 6e-32 110.4 9.3 9.4e-32 109.7 6.5 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) DUF814 PF05670.8 AET37307.1 - 0.0036 17.1 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Adenyl_cycl_N PF12633.2 AET37307.1 - 0.02 14.4 0.1 0.045 13.2 0.1 1.7 1 0 0 1 1 1 0 Adenylate cyclase NT domain Complex1_LYR PF05347.10 AET37308.1 - 1.4e-08 34.4 0.1 4.2e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AET37308.1 - 1.9e-08 34.3 0.7 4.4e-08 33.2 0.0 1.9 3 0 0 3 3 3 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 AET37308.1 - 1.1e-05 25.8 0.2 1.7e-05 25.2 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Histidinol_dh PF00815.15 AET37309.1 - 5.6e-184 611.5 1.9 7.4e-184 611.1 1.3 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 AET37309.1 - 1.6e-26 91.7 0.0 3e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 AET37309.1 - 2e-10 40.8 0.9 4e-10 39.8 0.2 1.8 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase CAP_GLY PF01302.20 AET37310.1 - 1.5e-15 56.6 0.4 3.7e-15 55.3 0.2 1.7 1 0 0 1 1 1 1 CAP-Gly domain Tropomyosin_1 PF12718.2 AET37310.1 - 0.00034 20.4 12.3 0.00034 20.4 8.5 3.1 3 1 1 4 4 4 1 Tropomyosin like CCDC144C PF14915.1 AET37310.1 - 0.0089 14.9 33.6 0.009 14.9 21.0 2.2 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region MinE PF03776.9 AET37310.1 - 0.011 15.2 4.7 0.035 13.6 3.3 1.9 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE GAS PF13851.1 AET37310.1 - 0.023 13.9 36.9 0.052 12.7 17.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 AET37310.1 - 0.38 8.0 33.8 0.73 7.0 16.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 AET37310.1 - 1 9.1 33.4 0.14 11.8 6.8 3.7 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 AET37310.1 - 1.4 7.8 35.5 1.7 7.5 14.6 2.7 2 1 1 3 3 3 0 Autophagy protein Apg6 Corona_S2 PF01601.11 AET37310.1 - 4 5.4 7.7 0.17 9.9 0.3 2.0 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein Allexi_40kDa PF05549.6 AET37310.1 - 4.3 6.5 14.5 0.28 10.4 3.2 2.4 1 1 1 2 2 2 0 Allexivirus 40kDa protein TPR_11 PF13414.1 AET37311.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 TPR repeat CAP PF00188.21 AET37312.1 - 4.5e-21 75.6 2.1 7.1e-21 74.9 1.4 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SH3_9 PF14604.1 AET37313.1 - 2.9e-05 23.5 0.0 0.0002 20.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 AET37313.1 - 0.02 14.2 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 SH3 domain DUF1201 PF06716.6 AET37313.1 - 0.1 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) AA_permease PF00324.16 AET37314.1 - 1.2e-126 422.8 37.7 1.4e-126 422.6 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET37314.1 - 1.5e-30 106.1 37.8 1.8e-30 105.8 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 AET37314.1 - 0.72 8.3 11.1 0.61 8.5 1.3 3.1 2 2 0 2 2 2 0 Predicted membrane protein (DUF2207) Rad60-SLD PF11976.3 AET37315.1 - 3.8e-20 71.3 0.1 4.9e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 AET37315.1 - 7.6e-10 38.0 0.0 9.6e-10 37.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 AET37315.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Pkinase PF00069.20 AET37316.1 - 4.7e-73 245.5 0.0 2.5e-72 243.1 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37316.1 - 9.8e-34 116.5 0.0 2.5e-33 115.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET37316.1 - 4.8e-07 29.0 0.0 4.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Cu-oxidase_2 PF07731.9 AET37317.1 - 8.6e-33 112.7 3.0 3.1e-26 91.5 0.7 3.5 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 AET37317.1 - 4.4e-28 97.3 3.1 6.4e-27 93.6 0.5 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 AET37317.1 - 1.9e-24 86.3 1.1 2.2e-22 79.6 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase PSP1 PF04468.7 AET37318.1 - 4.8e-33 112.9 3.5 4.8e-33 112.9 2.4 3.0 2 1 0 2 2 2 1 PSP1 C-terminal conserved region OmpH PF03938.9 AET37318.1 - 8.4e-06 25.7 19.1 1.7e-05 24.8 13.2 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DDHD PF02862.12 AET37318.1 - 0.59 9.8 18.9 0.22 11.2 7.3 2.7 2 0 0 2 2 2 0 DDHD domain eIF-3_zeta PF05091.7 AET37318.1 - 3.6 6.0 21.3 5.7 5.4 14.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FLO_LFY PF01698.11 AET37318.1 - 4.4 6.0 14.9 8.4 5.1 10.3 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Suf PF05843.9 AET37318.1 - 5.3 6.6 27.5 16 5.0 17.0 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 AET37318.1 - 6.1 6.6 27.9 18 5.1 19.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Tim54 PF11711.3 AET37318.1 - 8.5 4.8 14.6 15 4.0 10.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PBP PF01161.15 AET37319.1 - 1.4e-29 102.8 0.0 1.6e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Cupin_3 PF05899.7 AET37319.1 - 0.00065 19.0 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) PAP2 PF01569.16 AET37320.1 - 2.9e-20 72.2 5.1 3e-20 72.2 2.3 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 AET37320.1 - 0.00025 21.2 1.0 0.0018 18.4 0.6 2.4 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 AET37320.1 - 0.015 14.8 0.1 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 PAP2 superfamily S-AdoMet_synt_C PF02773.11 AET37321.1 - 1.1e-73 245.5 0.2 1.7e-73 244.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 AET37321.1 - 1.4e-46 157.3 0.0 3.2e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 AET37321.1 - 3.8e-44 148.9 0.1 7.3e-44 148.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DUF605 PF04652.11 AET37322.1 - 4.4e-42 144.8 11.1 2.6e-25 89.6 0.1 2.0 1 1 1 2 2 2 2 Vta1 like DUF4508 PF14969.1 AET37322.1 - 0.11 12.5 0.1 0.31 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Ank PF00023.25 AET37323.1 - 1.1e-12 47.0 0.5 1.5e-06 27.7 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 AET37323.1 - 4.5e-12 46.1 0.0 5.7e-05 23.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AET37323.1 - 1.3e-10 40.4 1.0 3.3e-05 23.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 AET37323.1 - 8.3e-10 38.5 10.3 1.9e-07 31.1 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AET37323.1 - 6.5e-08 32.8 0.1 0.0013 19.1 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) IncA PF04156.9 AET37323.1 - 0.011 15.2 7.1 0.016 14.8 1.1 2.3 2 0 0 2 2 2 0 IncA protein OmpH PF03938.9 AET37323.1 - 0.045 13.6 8.1 0.15 12.0 2.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FHA PF00498.21 AET37324.1 - 1e-06 28.7 2.2 7e-06 26.0 0.0 3.3 4 0 0 4 4 4 1 FHA domain Ribosomal_L37e PF01907.14 AET37325.1 - 2e-28 97.9 11.7 2e-28 97.9 8.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 AET37325.1 - 0.00059 19.6 1.6 0.00089 19.0 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 AET37325.1 - 0.007 16.0 0.3 0.0089 15.7 0.2 1.2 1 0 0 1 1 1 1 SelR domain C1_1 PF00130.17 AET37325.1 - 0.041 13.6 2.5 0.066 12.9 1.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_6 PF14599.1 AET37325.1 - 0.042 13.6 1.9 0.06 13.1 1.3 1.2 1 0 0 1 1 1 0 Zinc-ribbon GATA PF00320.22 AET37325.1 - 0.16 11.3 6.2 0.56 9.5 1.0 2.4 1 1 1 2 2 2 0 GATA zinc finger zinc_ribbon_2 PF13240.1 AET37325.1 - 0.38 10.2 4.4 2.3 7.8 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AET37325.1 - 0.43 9.8 4.6 3.2 7.0 3.2 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 AET37325.1 - 2 8.1 5.6 3.2 7.4 3.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LCD1 PF09798.4 AET37326.1 - 7.6e-193 642.0 25.9 9.4e-193 641.7 17.9 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein EMG1 PF03587.9 AET37327.1 - 2.1e-76 255.7 0.0 2.5e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF1282 PF06930.7 AET37328.1 - 0.01 15.4 0.2 0.01 15.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1282) CD34_antigen PF06365.7 AET37328.1 - 0.032 13.8 0.2 0.65 9.6 0.0 2.9 3 0 0 3 3 3 0 CD34/Podocalyxin family Shisa PF13908.1 AET37328.1 - 0.035 14.2 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tape_meas_lam_C PF09718.5 AET37328.1 - 0.65 9.9 5.5 2.9 7.8 0.8 3.0 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DELLA PF12041.3 AET37328.1 - 0.83 9.3 4.2 1.3 8.7 0.8 2.8 2 1 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal SecE PF00584.15 AET37328.1 - 5.2 6.7 10.6 0.063 12.8 1.0 2.6 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex PH PF00169.24 AET37329.1 - 9.3e-07 29.0 0.0 0.00048 20.2 0.0 2.9 2 0 0 2 2 2 2 PH domain CsgF PF10614.4 AET37329.1 - 0.032 14.2 0.1 0.089 12.7 0.1 1.7 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein ABC_membrane PF00664.18 AET37330.1 - 1.5e-55 188.5 2.7 1.9e-55 188.2 1.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AET37330.1 - 7.7e-30 103.9 0.0 1.7e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 AET37330.1 - 1.5e-07 30.9 0.0 1.2e-05 24.6 0.0 2.3 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 AET37330.1 - 0.0015 19.3 0.0 0.0033 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 AET37330.1 - 0.0023 16.5 0.1 0.0038 15.8 0.1 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_21 PF13304.1 AET37330.1 - 0.0026 17.7 3.3 0.23 11.3 0.7 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AET37330.1 - 0.013 15.5 1.1 0.12 12.3 0.8 2.5 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 AET37330.1 - 0.021 14.6 0.1 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 AET37330.1 - 0.032 13.6 0.2 0.86 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 AET37330.1 - 0.035 13.8 0.0 0.2 11.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AET37330.1 - 0.042 13.9 0.2 0.46 10.6 0.1 2.4 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AET37330.1 - 0.07 13.0 0.6 0.39 10.6 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 AET37330.1 - 0.072 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 6PF2K PF01591.13 AET37330.1 - 0.087 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.24 AET37330.1 - 0.088 13.0 0.4 1.5 9.0 0.2 2.7 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AET37330.1 - 0.094 13.0 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AET37330.1 - 0.1 12.1 0.2 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Abhydrolase_1 PF00561.15 AET37331.1 - 1.6e-57 194.7 0.0 2.4e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AET37331.1 - 1.7e-12 47.7 0.4 7.7e-12 45.5 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AET37331.1 - 0.0002 21.1 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 AET37331.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein GRAM PF02893.15 AET37332.1 - 1.7e-26 91.4 1.1 4.8e-16 58.0 0.3 3.5 3 0 0 3 3 3 2 GRAM domain Glyco_transf_28 PF03033.15 AET37332.1 - 2.9e-25 88.6 0.0 6.6e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 AET37332.1 - 1.1e-08 35.2 4.3 2.6e-08 33.9 0.6 3.3 3 1 1 4 4 4 1 PH domain UDPGT PF00201.13 AET37332.1 - 0.00028 19.5 0.5 0.0008 18.0 0.3 1.7 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Exo_endo_phos PF03372.18 AET37333.1 - 9.8e-18 64.9 0.2 1.3e-17 64.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spindle_Spc25 PF08234.7 AET37334.1 - 5.3e-18 64.7 0.3 1.3e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 GAS PF13851.1 AET37334.1 - 0.0005 19.3 22.4 0.00085 18.5 15.5 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding APG6 PF04111.7 AET37334.1 - 0.0035 16.4 19.4 0.0051 15.9 13.4 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 UPF0184 PF03670.8 AET37334.1 - 0.021 14.9 6.2 0.093 12.9 2.7 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) AAA_13 PF13166.1 AET37334.1 - 0.025 13.0 14.9 0.032 12.6 10.3 1.1 1 0 0 1 1 1 0 AAA domain CCDC71L PF15374.1 AET37334.1 - 0.043 13.1 3.2 0.065 12.5 2.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Filament PF00038.16 AET37334.1 - 0.046 13.1 17.6 0.072 12.5 12.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein YjcZ PF13990.1 AET37334.1 - 0.15 11.1 5.6 0.23 10.5 3.9 1.3 1 0 0 1 1 1 0 YjcZ-like protein DUF342 PF03961.8 AET37334.1 - 0.2 10.0 11.2 0.3 9.4 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nup88 PF10168.4 AET37334.1 - 0.25 9.1 11.6 0.14 9.9 6.7 1.6 2 0 0 2 2 2 0 Nuclear pore component DUF3867 PF12983.2 AET37334.1 - 0.27 11.2 8.4 0.39 10.6 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) DUF972 PF06156.8 AET37334.1 - 0.45 10.8 16.5 0.19 12.1 7.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 AET37334.1 - 0.5 8.1 9.2 0.65 7.7 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC84 PF14968.1 AET37334.1 - 1 8.7 7.9 5.3 6.4 0.0 2.1 1 1 1 2 2 2 0 Coiled coil protein 84 DUF3450 PF11932.3 AET37334.1 - 2.3 7.4 18.4 0.27 10.4 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) AAA_11 PF13086.1 AET37334.1 - 2.7 7.4 9.1 4.2 6.8 6.3 1.3 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 AET37334.1 - 3.8 7.6 15.6 7 6.7 10.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 AET37334.1 - 5.3 6.5 20.4 5.9 6.3 10.8 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 AET37334.1 - 5.5 5.8 22.0 36 3.1 15.1 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Nup54 PF13874.1 AET37334.1 - 7.5 6.2 16.2 23 4.6 0.0 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Per1 PF04080.8 AET37335.1 - 1.5e-91 306.5 13.6 1.8e-91 306.3 9.4 1.0 1 0 0 1 1 1 1 Per1-like SET PF00856.23 AET37335.1 - 0.072 13.3 0.2 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 SET domain Ferric_reduct PF01794.14 AET37335.1 - 0.16 12.0 6.7 0.42 10.7 4.6 1.9 1 1 0 1 1 1 0 Ferric reductase like transmembrane component HCO3_cotransp PF00955.16 AET37336.1 - 7.3e-53 179.9 10.0 5.7e-34 117.6 1.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family Sulfate_tra_GLY PF13792.1 AET37336.1 - 0.095 12.3 4.8 2.9 7.6 0.3 3.2 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif PDR_assoc PF08370.6 AET37336.1 - 0.15 11.5 2.3 0.46 10.0 1.6 1.8 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Tic20 PF09685.5 AET37337.1 - 0.048 13.6 0.1 0.062 13.2 0.1 1.2 1 0 0 1 1 1 0 Tic20-like protein Sad1_UNC PF07738.8 AET37338.1 - 1.6e-34 118.6 0.0 3e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CCSMST1 PF15013.1 AET37338.1 - 0.066 13.1 0.1 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 CCSMST1 family Cyclin_N PF00134.18 AET37339.1 - 4.5e-32 110.2 1.2 1.2e-31 108.9 0.8 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AET37339.1 - 0.00044 20.1 0.2 0.0012 18.7 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain TIMELESS PF04821.9 AET37340.1 - 3.2e-48 164.3 0.0 1.8e-46 158.5 0.0 2.4 1 1 0 1 1 1 1 Timeless protein Aa_trans PF01490.13 AET37341.1 - 6.2e-84 281.8 31.1 7.2e-84 281.6 21.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sec2p PF06428.6 AET37342.1 - 2.3e-27 94.7 11.1 2.3e-27 94.7 7.7 3.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p LMBR1 PF04791.11 AET37342.1 - 0.022 13.3 1.1 0.073 11.6 0.8 1.9 1 1 0 1 1 1 0 LMBR1-like membrane protein GlnE PF03710.10 AET37342.1 - 1.7 7.8 8.7 3 7.0 5.4 1.9 1 1 1 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase FH2 PF02181.18 AET37343.1 - 1.5e-81 274.1 11.0 1.5e-81 274.1 7.6 3.4 5 0 0 5 5 5 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 AET37343.1 - 1.8e-48 164.5 8.5 1.9e-47 161.2 0.0 3.7 3 0 0 3 3 3 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 AET37343.1 - 1.4e-30 106.0 1.0 1.4e-30 106.0 0.7 3.7 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain VIT1 PF01988.14 AET37343.1 - 2.3 7.6 5.5 2.5 7.5 0.9 2.9 3 1 0 3 3 3 0 VIT family AA_permease PF00324.16 AET37344.1 - 3.3e-132 441.2 44.2 4e-132 440.9 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET37344.1 - 1.6e-34 119.2 50.6 2.6e-34 118.4 35.0 1.4 1 1 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.3 AET37344.1 - 1.6 8.2 9.3 0.19 11.1 0.2 3.2 3 0 0 3 3 3 0 Intrinsic membrane protein PufX AA_permease PF00324.16 AET37345.1 - 7.1e-130 433.5 46.7 8.1e-130 433.3 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET37345.1 - 6.5e-38 130.3 52.9 8.2e-38 130.0 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.3 AET37345.1 - 1.6 8.1 10.5 0.14 11.5 0.2 3.6 4 0 0 4 4 4 0 Intrinsic membrane protein PufX PI3_PI4_kinase PF00454.22 AET37346.1 - 6e-32 111.0 0.1 1.3e-31 109.9 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 AET37346.1 - 1.1e-20 73.0 2.0 3.7e-20 71.4 1.4 2.0 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 AET37346.1 - 1.2e-06 27.7 0.6 3.6e-06 26.2 0.4 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 AET37346.1 - 0.012 14.6 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Mmp37 PF09139.6 AET37347.1 - 1.8e-105 352.5 9.1 4.9e-97 324.8 1.1 2.0 1 1 1 2 2 2 2 Mitochondrial matrix Mmp37 Ist1 PF03398.9 AET37348.1 - 2e-55 186.7 2.0 3e-55 186.1 1.4 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF1771 PF08590.5 AET37348.1 - 0.17 11.9 3.6 0.31 11.0 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) ADH_N PF08240.7 AET37349.1 - 4.9e-27 93.8 4.6 1e-26 92.8 3.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AET37349.1 - 2.9e-18 65.6 0.0 4.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AET37349.1 - 8.1e-05 21.8 0.1 0.00014 21.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 AET37349.1 - 0.0062 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 AET37349.1 - 0.025 14.5 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 AET37349.1 - 0.06 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 AET37349.1 - 0.061 13.7 1.2 0.27 11.6 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.17 AET37349.1 - 0.074 13.5 0.0 0.18 12.3 0.0 1.6 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.11 AET37349.1 - 0.11 11.8 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UFD1 PF03152.9 AET37350.1 - 3.6e-71 237.9 0.0 4.5e-71 237.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF2422 PF10337.4 AET37351.1 - 1.1e-50 172.7 2.4 1.5e-50 172.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 AET37351.1 - 1.1e-11 44.7 12.6 1.1e-11 44.7 8.7 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 AET37351.1 - 6.8e-05 22.5 0.1 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 AET37351.1 - 0.00031 19.5 9.0 0.017 13.7 2.8 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter CRAL_TRIO PF00650.15 AET37352.1 - 1.8e-38 131.5 0.0 2.9e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AET37352.1 - 2.3e-12 46.8 1.5 7.5e-12 45.1 0.2 2.4 2 1 1 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AET37352.1 - 2.2e-05 24.3 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UBA_4 PF14555.1 AET37352.1 - 0.033 13.7 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain DnaJ PF00226.26 AET37353.1 - 5.1e-16 58.1 1.5 8.7e-16 57.4 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain Acyl-CoA_ox_N PF14749.1 AET37353.1 - 2.3 8.5 7.2 2.1 8.6 2.6 2.4 2 1 1 3 3 3 0 Acyl-coenzyme A oxidase N-terminal YIF1 PF03878.10 AET37354.1 - 1.4e-70 237.2 6.4 1.7e-70 236.8 4.5 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 AET37354.1 - 0.0012 18.3 1.5 0.0012 18.3 1.1 1.7 2 0 0 2 2 2 1 Yip1 domain Glyco_transf_52 PF07922.6 AET37354.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 52 DUF1744 PF08490.7 AET37355.1 - 1e-148 495.1 7.1 1.6e-148 494.5 4.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 AET37355.1 - 2.4e-68 230.3 3.8 6.2e-68 229.0 2.6 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 AET37355.1 - 2.6e-24 85.8 2.7 1.1e-21 77.1 0.4 2.6 2 0 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 AET37355.1 - 1.6e-07 31.1 0.7 8.7e-07 28.6 0.3 2.5 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB ORC5_C PF14630.1 AET37356.1 - 1.5e-65 221.3 0.4 2.2e-65 220.8 0.3 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 AET37356.1 - 5.7e-06 26.4 0.0 2.4e-05 24.4 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain CRAL_TRIO_2 PF13716.1 AET37356.1 - 0.0006 19.7 0.9 0.006 16.5 0.1 2.6 2 2 1 3 3 3 1 Divergent CRAL/TRIO domain AAA_22 PF13401.1 AET37356.1 - 0.0033 17.5 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF4211 PF13926.1 AET37356.1 - 0.054 12.9 0.2 0.2 11.0 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) Glypican PF01153.14 AET37356.1 - 0.16 10.5 0.1 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Glypican GYF PF02213.11 AET37357.1 - 1.6e-08 34.0 1.7 1.6e-08 34.0 1.2 2.1 2 0 0 2 2 2 1 GYF domain Yae1_N PF09811.4 AET37358.1 - 8.8e-08 31.5 5.5 4.7e-07 29.2 3.8 2.0 1 1 0 1 1 1 1 Essential protein Yae1, N terminal RTC4 PF14474.1 AET37359.1 - 4.8e-34 116.9 0.0 1e-33 115.9 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain HSP20 PF00011.16 AET37360.1 - 6.9e-20 70.8 0.1 1e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 AET37360.1 - 0.021 14.5 0.1 4 7.2 0.0 2.5 2 0 0 2 2 2 0 BON domain MRP-L46 PF11788.3 AET37361.1 - 3.7e-38 130.5 0.2 6.9e-38 129.7 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 RRM_1 PF00076.17 AET37362.1 - 1.5e-07 30.9 0.0 3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET37362.1 - 8e-07 28.9 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET37362.1 - 2.1e-05 24.2 0.0 4.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 AET37362.1 - 3.6 5.7 13.9 4.6 5.3 9.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Rad50_zn_hook PF04423.9 AET37363.1 - 1.1e-12 47.1 3.3 1.1e-12 47.1 2.3 5.7 5 0 0 5 5 5 1 Rad50 zinc hook motif SbcCD_C PF13558.1 AET37363.1 - 4.2e-11 42.6 0.0 1.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 AET37363.1 - 2.1e-08 33.6 0.1 2.1e-08 33.6 0.1 3.1 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AET37363.1 - 3.1e-08 34.1 146.5 2.2e+03 -1.3 0.5 8.4 1 1 2 3 3 1 0 AAA domain AAA_13 PF13166.1 AET37363.1 - 1.1e-07 30.7 133.1 5e-05 21.9 0.0 6.9 2 1 2 6 6 6 4 AAA domain IncA PF04156.9 AET37363.1 - 0.00046 19.8 14.7 0.00046 19.8 10.2 8.9 2 1 5 7 7 6 2 IncA protein AAA_21 PF13304.1 AET37363.1 - 0.00053 20.0 0.0 0.00053 20.0 0.0 6.5 3 1 2 5 5 4 1 AAA domain APG6 PF04111.7 AET37363.1 - 0.0025 16.9 9.2 0.0025 16.9 6.4 8.5 1 1 9 11 11 10 3 Autophagy protein Apg6 AAA_29 PF13555.1 AET37363.1 - 0.005 16.3 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spectrin PF00435.16 AET37363.1 - 0.0094 16.2 3.6 0.0094 16.2 2.5 10.0 5 2 8 13 13 12 2 Spectrin repeat ABC_tran PF00005.22 AET37363.1 - 0.015 15.6 0.0 0.015 15.6 0.0 6.5 4 2 0 4 4 3 0 ABC transporter AAA_16 PF13191.1 AET37363.1 - 0.017 15.0 5.2 0.32 10.9 0.0 3.9 2 1 1 3 3 3 0 AAA ATPase domain HAMP PF00672.20 AET37363.1 - 0.25 11.5 1.2 1.7 8.8 0.1 3.0 3 0 0 3 3 2 0 HAMP domain AAA_19 PF13245.1 AET37363.1 - 0.26 11.0 0.0 0.6 9.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Laminin_II PF06009.7 AET37363.1 - 1.3 8.7 81.9 0.03 14.0 3.1 9.7 5 3 4 9 9 9 0 Laminin Domain II RNA_pol_I_A49 PF06870.7 AET37364.1 - 7.3e-130 432.9 1.5 8.2e-130 432.8 1.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Zwint PF15556.1 AET37364.1 - 0.019 14.2 1.2 0.18 11.0 0.0 2.5 3 0 0 3 3 3 0 ZW10 interactor DnaJ PF00226.26 AET37365.1 - 7.4e-18 64.0 1.8 9.9e-18 63.6 1.2 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 AET37365.1 - 3.9e-17 61.5 0.4 6.4e-17 60.8 0.3 1.4 1 0 0 1 1 1 1 CSL zinc finger RPT PF13446.1 AET37365.1 - 0.00021 20.6 0.0 0.00046 19.5 0.0 1.5 2 0 0 2 2 2 1 A repeated domain in UCH-protein NAP PF00956.13 AET37366.1 - 5.3e-19 68.2 3.1 1.7e-12 47.0 0.2 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) SUI1 PF01253.17 AET37367.1 - 7.9e-29 99.3 0.4 9.5e-29 99.0 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.3 AET37367.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Cas_Csa5 PF09702.5 AET37367.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) MAT_Alpha1 PF04769.7 AET37368.1 - 3.5e-10 39.5 5.5 9.8e-10 38.0 0.9 2.5 1 1 0 1 1 1 1 Mating-type protein MAT alpha 1 Homeobox_KN PF05920.6 AET37369.1 - 4.8e-07 29.3 0.5 1.1e-06 28.1 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 AET37369.1 - 3.7e-06 26.4 0.4 1.1e-05 24.9 0.2 1.8 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 AET37369.1 - 0.0004 19.3 0.0 0.00076 18.4 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 AET37369.1 - 0.03 14.3 0.0 0.077 13.1 0.0 1.7 1 1 0 1 1 1 0 Helicase associated domain HTH_28 PF13518.1 AET37369.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1160 PF06648.6 AET37369.1 - 0.12 12.1 1.4 0.31 10.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Sec10 PF07393.6 AET37370.1 - 1.4e-55 188.8 8.4 1.2e-54 185.7 5.3 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec10 NAD_Gly3P_dh_C PF07479.9 AET37370.1 - 0.022 14.5 0.1 1.6 8.4 0.0 2.7 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus PRP21_like_P PF12230.3 AET37371.1 - 4.4e-35 121.2 8.5 4.4e-35 121.2 5.9 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 AET37371.1 - 2.5e-05 23.8 4.7 0.00042 19.8 0.0 2.8 2 0 0 2 2 2 2 Surp module zf-CCHC PF00098.18 AET37372.1 - 4.5e-51 168.4 51.9 4.1e-09 35.9 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 AET37372.1 - 1.4e-08 34.2 45.5 0.015 14.9 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 AET37372.1 - 0.00094 18.8 42.3 2.3 8.0 0.7 7.1 1 1 6 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 AET37372.1 - 0.36 10.3 50.1 0.17 11.4 0.5 7.0 2 2 5 7 7 7 0 Zinc knuckle Pterin_bind PF00809.17 AET37373.1 - 2.3e-48 164.3 0.4 4.7e-47 160.0 0.3 2.4 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 AET37373.1 - 4e-37 126.7 0.0 8.6e-37 125.7 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 AET37373.1 - 1.3e-35 121.9 1.3 1.1e-17 64.2 0.0 3.1 3 0 0 3 3 3 2 Dihydroneopterin aldolase FAD_binding_3 PF01494.14 AET37374.1 - 6e-17 61.7 0.1 1.2e-07 31.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.7 AET37374.1 - 8.6e-06 24.9 0.0 0.0039 16.1 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 AET37374.1 - 0.00072 18.5 0.0 0.016 14.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AET37374.1 - 0.0074 16.2 0.1 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AET37374.1 - 0.0099 14.9 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.9 AET37374.1 - 0.013 14.1 0.1 0.21 10.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 AET37374.1 - 0.022 13.6 0.1 0.038 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 AET37374.1 - 0.026 14.3 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 AET37374.1 - 0.059 12.1 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.22 AET37374.1 - 0.12 12.7 0.0 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AET37374.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 AET37374.1 - 0.13 10.7 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.1 AET37374.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) RRM_1 PF00076.17 AET37375.1 - 6.9e-17 60.8 0.1 1.4e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 AET37375.1 - 7.6e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_6 PF14259.1 AET37375.1 - 2.8e-14 52.8 0.0 5.7e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET37375.1 - 5.5e-13 48.5 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AET37375.1 - 0.046 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif OB_RNB PF08206.6 AET37375.1 - 0.082 12.4 0.5 1.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain PGAP1 PF07819.8 AET37376.1 - 1.6e-07 31.1 0.0 3.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 AET37376.1 - 4.1e-05 22.9 0.0 7.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.6 AET37376.1 - 0.0002 20.5 0.0 0.0024 17.0 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 AET37376.1 - 0.00033 20.2 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 AET37376.1 - 0.0023 16.9 0.1 0.0076 15.2 0.0 1.6 1 1 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 AET37376.1 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PFK PF00365.15 AET37376.1 - 0.031 13.2 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase Abhydrolase_5 PF12695.2 AET37376.1 - 0.057 13.1 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family PH PF00169.24 AET37377.1 - 2e-06 27.9 0.2 2.7e-05 24.3 0.1 3.0 1 1 0 1 1 1 1 PH domain HMA PF00403.21 AET37378.1 - 9.6e-10 38.4 0.1 1.2e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Allantoicase PF03561.10 AET37379.1 - 1.2e-99 330.0 0.1 8e-55 184.4 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DUF793 PF05633.6 AET37379.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Methyltransf_16 PF10294.4 AET37380.1 - 1.7e-16 60.1 0.5 4.4e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 AET37380.1 - 0.036 13.4 0.0 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 AET37380.1 - 0.077 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF948 PF06103.6 AET37381.1 - 0.32 10.8 2.7 1.3 8.9 0.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GAS PF13851.1 AET37381.1 - 0.54 9.4 24.1 1.4 8.0 1.3 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF349 PF03993.7 AET37381.1 - 0.69 10.1 6.1 1.5 9.0 4.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Myosin_tail_1 PF01576.14 AET37381.1 - 1.8 6.2 27.7 1.3 6.6 12.8 2.3 1 1 0 2 2 2 0 Myosin tail Cauli_AT PF03233.8 AET37381.1 - 3 7.5 10.8 0.15 11.7 2.9 2.2 2 1 1 3 3 3 0 Aphid transmission protein APG6 PF04111.7 AET37381.1 - 3.2 6.7 25.8 0.097 11.6 10.8 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 MCC-bdg_PDZ PF10506.4 AET37381.1 - 3.9 7.3 11.7 3.9 7.3 1.8 3.7 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF2570 PF10828.3 AET37381.1 - 4.4 6.9 12.7 0.97 9.0 5.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) TPR_MLP1_2 PF07926.7 AET37381.1 - 10 5.9 30.0 6.4 6.5 15.9 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Dus PF01207.12 AET37382.1 - 2.5e-79 266.3 0.0 3.3e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M28 PF04389.12 AET37383.1 - 3e-16 59.6 0.0 5.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 AET37383.1 - 2.4e-14 52.9 0.0 5.8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M20 PF01546.23 AET37383.1 - 1.5e-05 24.5 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.17 AET37383.1 - 1.8e-05 24.3 0.0 7.3e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 PA domain NumbF PF06311.7 AET37383.1 - 0.037 14.1 0.2 4.7 7.3 0.1 2.5 2 0 0 2 2 2 0 NUMB domain DUF1415 PF07209.7 AET37383.1 - 0.13 12.0 0.2 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) Pro_isomerase PF00160.16 AET37384.1 - 1.7e-47 161.4 0.1 2e-47 161.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M50 PF02163.17 AET37384.1 - 0.1 11.5 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 ENTH PF01417.15 AET37385.1 - 4.9e-41 139.5 0.0 7.5e-41 138.8 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Herpes_UL17 PF04559.7 AET37385.1 - 0.097 11.2 0.1 0.21 10.1 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus UL17 protein Sybindin PF04099.7 AET37386.1 - 1.3e-20 73.5 0.1 1.6e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Sybindin-like family Zn_clus PF00172.13 AET37387.1 - 0.0021 17.9 7.9 0.0037 17.1 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SBP PF03110.9 AET37387.1 - 0.048 13.8 3.0 0.15 12.2 2.1 1.8 1 0 0 1 1 1 0 SBP domain HMG-CoA_red PF00368.13 AET37388.1 - 3.6e-158 526.1 0.1 4.6e-158 525.7 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 AET37388.1 - 7.7e-41 139.3 1.3 1.5e-40 138.3 0.9 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 AET37388.1 - 1.2e-08 34.5 7.3 3.2e-08 33.1 5.0 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation FKBP_C PF00254.23 AET37389.1 - 5.9e-28 96.7 0.6 3.1e-27 94.4 0.1 2.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase AAA_11 PF13086.1 AET37389.1 - 0.28 10.7 10.9 0.1 12.1 0.6 2.2 2 0 0 2 2 2 0 AAA domain GAGA_bind PF06217.7 AET37389.1 - 5.6 6.8 21.3 4.5 7.1 2.5 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Ribosomal_L6e PF01159.14 AET37390.1 - 3.6e-41 139.7 2.7 5.6e-41 139.1 1.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e DUF3616 PF12275.3 AET37390.1 - 0.059 12.3 0.6 0.08 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) C2 PF00168.25 AET37391.1 - 2.1e-37 126.8 0.2 6e-17 61.2 0.0 5.5 5 0 0 5 5 5 4 C2 domain DUF92 PF01940.11 AET37391.1 - 0.0034 16.5 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Integral membrane protein DUF92 Dor1 PF04124.7 AET37392.1 - 9.6e-22 76.8 16.2 7.1e-20 70.7 11.2 2.1 1 1 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 AET37392.1 - 7.7e-07 29.0 3.1 1.6e-06 27.9 0.4 2.4 1 1 1 2 2 2 1 Exocyst complex component Sec5 HrcA PF01628.16 AET37392.1 - 0.016 14.8 4.7 0.28 10.7 0.6 2.8 3 0 0 3 3 3 0 HrcA protein C terminal domain PhoU PF01895.14 AET37392.1 - 0.047 14.1 7.9 17 5.9 1.7 4.3 2 2 1 3 3 3 0 PhoU domain Dockerin_1 PF00404.13 AET37392.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Dockerin type I repeat YfcL PF08891.6 AET37392.1 - 0.13 12.2 1.0 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 YfcL protein vATP-synt_AC39 PF01992.11 AET37393.1 - 8.8e-85 284.7 0.8 1e-84 284.5 0.6 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit cNMP_binding PF00027.24 AET37394.1 - 1.5e-37 127.3 0.4 1.6e-17 63.1 0.0 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain F-box PF00646.28 AET37394.1 - 4e-07 29.5 1.3 1.7e-06 27.4 0.9 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AET37394.1 - 7.9e-06 25.4 0.5 2.7e-05 23.7 0.4 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 AET37394.1 - 3.9e-05 23.2 26.4 0.29 11.3 0.1 7.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 AET37394.1 - 0.0022 17.6 19.2 0.0028 17.2 1.2 6.0 5 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AET37394.1 - 0.014 15.2 24.5 4.9 7.5 0.2 9.1 8 2 1 9 9 9 0 Leucine Rich Repeat Dynamin_M PF01031.15 AET37394.1 - 0.015 14.0 0.1 0.032 12.9 0.0 1.5 1 0 0 1 1 1 0 Dynamin central region LRR_7 PF13504.1 AET37394.1 - 1.6 9.2 19.2 2.9 8.4 0.2 6.7 7 0 0 7 7 7 0 Leucine rich repeat Cyt-b5 PF00173.23 AET37395.1 - 1.7e-08 34.1 0.1 4.6e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Hexokinase_1 PF00349.16 AET37396.1 - 1.7e-07 30.7 0.2 4.7e-07 29.3 0.1 1.6 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.11 AET37396.1 - 0.023 13.9 0.0 3.8 6.6 0.0 2.2 1 1 1 2 2 2 0 Hexokinase CoA_binding_2 PF13380.1 AET37397.1 - 5.6e-22 78.1 0.0 9.2e-22 77.4 0.0 1.3 1 1 0 1 1 1 1 CoA binding domain Zn_clus PF00172.13 AET37398.1 - 9.7e-08 31.7 8.9 1.7e-07 31.0 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF16 PF01519.11 AET37398.1 - 3.9 7.7 7.7 0.58 10.3 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 BAR PF03114.13 AET37399.1 - 6.7e-16 58.4 0.8 1.8e-15 57.0 0.5 1.6 1 1 0 1 1 1 1 BAR domain SH3_9 PF14604.1 AET37399.1 - 6.1e-14 51.3 0.1 1.4e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AET37399.1 - 1.1e-12 47.1 0.1 2.2e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AET37399.1 - 8.7e-12 44.3 0.0 1.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF948 PF06103.6 AET37399.1 - 0.15 11.9 1.7 15 5.5 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 AET37399.1 - 1.3 9.4 6.3 16 5.8 2.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Dak1 PF02733.12 AET37400.1 - 3.2e-132 440.0 0.9 4.3e-132 439.6 0.7 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 AET37400.1 - 2.8e-44 150.8 0.0 4.7e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 DAK2 domain SSrecog PF03531.9 AET37401.1 - 2.5e-71 239.5 1.3 6.6e-71 238.1 0.4 2.1 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 AET37401.1 - 2.6e-28 97.8 0.1 3.1e-26 91.1 0.0 3.3 4 0 0 4 4 4 1 Histone chaperone Rttp106-like COPIIcoated_ERV PF07970.7 AET37402.1 - 3.7e-27 95.4 0.1 5.5e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AET37402.1 - 3.5e-20 71.7 0.0 7e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) GpcrRhopsn4 PF10192.4 AET37403.1 - 0.029 13.5 7.6 0.057 12.6 2.0 2.7 3 1 0 3 3 3 0 Rhodopsin-like GPCR transmembrane domain SUR7 PF06687.7 AET37404.1 - 4.5e-08 32.9 9.5 7.9e-08 32.1 6.6 1.4 1 0 0 1 1 1 1 SUR7/PalI family Transp_cyt_pur PF02133.10 AET37404.1 - 0.00057 18.5 0.5 0.0011 17.6 0.4 1.5 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF912 PF06024.7 AET37404.1 - 0.037 14.0 0.2 0.037 14.0 0.2 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3300 PF11737.3 AET37404.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) AAA PF00004.24 AET37405.1 - 6.2e-19 68.5 0.0 1.3e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AET37405.1 - 5.6e-08 32.9 0.0 6.7e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AET37405.1 - 1.5e-07 31.6 0.0 1.1e-06 28.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AET37405.1 - 2.5e-07 30.6 5.4 4.6e-06 26.5 0.0 2.9 3 0 0 3 3 3 2 Archaeal ATPase BAH PF01426.13 AET37405.1 - 2.4e-06 27.2 0.1 8e-06 25.6 0.1 2.0 1 0 0 1 1 1 1 BAH domain AAA_18 PF13238.1 AET37405.1 - 0.0018 18.5 0.5 0.019 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AET37405.1 - 0.0026 18.5 0.0 0.013 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AET37405.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 AET37405.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Ras PF00071.17 AET37406.1 - 5.2e-30 103.9 0.1 6.4e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET37406.1 - 6.6e-19 68.5 0.0 1.8e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AET37406.1 - 7.2e-05 22.0 0.1 9.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET37406.1 - 0.00012 21.3 0.1 0.00015 21.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AET37406.1 - 0.00092 18.6 0.1 0.016 14.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AET37406.1 - 0.0036 17.2 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 AET37406.1 - 0.051 13.0 0.3 0.36 10.3 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 AET37406.1 - 0.081 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_S3Ae PF01015.13 AET37407.1 - 8.3e-80 266.7 7.3 9.7e-80 266.4 5.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 AET37407.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ribosomal_L22 PF00237.14 AET37407.1 - 0.14 12.1 1.6 4.2 7.3 1.0 2.5 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e THOC7 PF05615.8 AET37408.1 - 3.4e-12 46.8 3.3 6.9e-12 45.8 0.8 2.4 2 0 0 2 2 2 1 Tho complex subunit 7 DUF4546 PF15079.1 AET37408.1 - 0.01 15.0 0.3 0.01 15.0 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4546) IncA PF04156.9 AET37408.1 - 3 7.4 7.6 20 4.6 0.1 2.7 2 1 0 2 2 2 0 IncA protein Sec39 PF08314.6 AET37409.1 - 4.8e-128 428.1 8.4 5.5e-128 427.9 5.8 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 PIF1 PF05970.9 AET37410.1 - 1.1e-68 231.8 2.3 1.2e-52 179.0 0.2 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 AET37410.1 - 4.1e-11 42.8 0.0 8.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AET37410.1 - 1.1e-05 25.5 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 AET37410.1 - 0.00029 20.9 0.1 0.0039 17.2 0.0 2.7 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 AET37410.1 - 0.00035 18.4 0.1 0.0032 15.3 0.0 2.1 2 0 0 2 2 2 1 Helicase T2SE PF00437.15 AET37410.1 - 0.00071 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 AET37410.1 - 0.026 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 AET37410.1 - 0.032 13.9 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 AET37410.1 - 0.043 13.4 0.1 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 AET37410.1 - 0.049 13.5 0.1 0.41 10.5 0.0 2.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AET37410.1 - 0.066 13.3 0.0 0.27 11.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 AET37410.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 AET37410.1 - 0.081 13.1 0.1 0.31 11.2 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 AET37410.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 AET37410.1 - 0.17 10.8 3.3 0.23 10.3 0.0 2.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) MRP-L47 PF06984.8 AET37411.1 - 4.5e-24 84.1 2.7 1.3e-23 82.7 1.9 1.8 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2884 PF11101.3 AET37411.1 - 0.033 13.5 3.2 0.045 13.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) LSM PF01423.17 AET37412.1 - 1.2e-17 63.1 0.1 1.4e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2272 PF10030.4 AET37412.1 - 0.044 13.2 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) cNMP_binding PF00027.24 AET37413.1 - 3.2e-36 123.0 0.6 3.4e-15 55.6 0.0 4.6 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 AET37413.1 - 1.6e-19 70.6 1.3 1.2e-12 48.1 0.6 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase Fibrinogen_BP PF08017.6 AET37413.1 - 0.0049 15.1 1.4 0.0079 14.4 1.0 1.2 1 0 0 1 1 1 1 Fibrinogen binding protein Aminotran_3 PF00202.16 AET37414.1 - 2e-104 349.1 0.0 2.4e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 AET37414.1 - 3.4e-06 26.4 0.0 6.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase RNR_inhib PF08591.5 AET37415.1 - 1.1e-16 61.5 0.1 2e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor UCH PF00443.24 AET37416.1 - 7.9e-35 120.2 5.5 3.4e-32 111.6 0.5 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SH3_1 PF00018.23 AET37417.1 - 3.1e-24 84.0 0.0 2.5e-12 45.9 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 AET37417.1 - 1.3e-15 56.7 0.1 6.7e-11 41.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 AET37417.1 - 7.8e-14 51.4 0.0 1.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 AET37417.1 - 6.1e-11 41.6 0.0 5e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.19 AET37417.1 - 6.5e-06 25.7 0.2 1.4e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 PB1 domain SelB-wing_2 PF09106.6 AET37417.1 - 0.013 15.4 0.1 4.6 7.2 0.0 2.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix VPS9 PF02204.13 AET37419.1 - 1.2e-17 63.7 1.9 3.4e-17 62.3 1.3 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain polyprenyl_synt PF00348.12 AET37420.1 - 5.7e-43 146.6 0.0 7.2e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DER1 PF04511.10 AET37421.1 - 0.00047 19.7 6.7 0.0011 18.5 4.7 1.6 1 1 0 1 1 1 1 Der1-like family TraC PF07820.7 AET37422.1 - 0.083 13.0 0.3 1.6 8.9 0.1 2.9 3 0 0 3 3 3 0 TraC-like protein Nnf1 PF03980.9 AET37422.1 - 4 7.4 6.7 4.4 7.3 1.8 2.9 2 1 0 2 2 2 0 Nnf1 MCM PF00493.18 AET37423.1 - 1.3e-134 448.2 0.0 2e-134 447.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AET37423.1 - 7.7e-26 90.9 0.1 2.4e-25 89.3 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AET37423.1 - 4.4e-07 29.2 0.0 7.6e-05 21.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AET37423.1 - 2.6e-06 27.1 0.0 1.9e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 AET37423.1 - 0.00016 22.0 1.0 0.00045 20.5 0.3 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AET37423.1 - 0.035 13.7 0.0 0.14 11.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AHS1 PF02682.11 AET37423.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 VPS28 PF03997.7 AET37425.1 - 2.1e-68 229.6 1.1 2.5e-68 229.4 0.8 1.0 1 0 0 1 1 1 1 VPS28 protein DUF3890 PF13029.1 AET37425.1 - 0.0083 16.1 1.7 0.3 11.1 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3890) DUF2465 PF10239.4 AET37425.1 - 0.013 14.6 0.7 0.03 13.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2465) DUF1759 PF03564.10 AET37425.1 - 0.28 10.9 6.5 0.75 9.5 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) Pro_isomerase PF00160.16 AET37426.1 - 7e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc82 PF05645.8 AET37426.1 - 0.017 14.6 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 NIF PF03031.13 AET37427.1 - 2.1e-38 131.4 0.0 4.4e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase F-box-like PF12937.2 AET37428.1 - 0.019 14.6 0.0 0.053 13.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like Abhydrolase_6 PF12697.2 AET37429.1 - 6.4e-16 58.9 0.0 1.1e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AET37429.1 - 3.3e-07 30.1 0.0 7.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 AET37429.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 AET37429.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF2424 PF10340.4 AET37430.1 - 2.6e-36 125.0 0.1 2.8e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 AET37430.1 - 1.1e-10 41.4 0.0 1.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGP_phosphatase PF09419.5 AET37430.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Glyco_transf_15 PF01793.11 AET37431.1 - 3.7e-125 417.2 8.1 4.6e-125 416.9 5.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CorA PF01544.13 AET37432.1 - 0.00039 19.5 7.5 0.00079 18.5 5.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Dict-STAT-coil PF09267.5 AET37432.1 - 0.015 15.5 0.3 0.015 15.5 0.2 2.8 4 1 0 4 4 4 0 Dictyostelium STAT, coiled coil FTR1 PF03239.9 AET37433.1 - 1.7e-96 322.7 10.6 2e-96 322.5 7.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Amidase PF01425.16 AET37434.1 - 2.3e-88 297.0 0.0 3.6e-88 296.3 0.0 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 AET37434.1 - 9.1e-83 277.6 0.0 1.5e-82 276.9 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 AET37434.1 - 3.1e-64 216.1 0.0 6e-64 215.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 AET37434.1 - 8.3e-46 156.0 0.0 1.8e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 AET37434.1 - 4.3e-37 126.5 0.0 2.1e-36 124.3 0.0 2.3 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AET37434.1 - 9e-34 115.6 0.0 2.2e-33 114.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 AET37434.1 - 9e-18 63.6 1.3 2.5e-17 62.2 0.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 AET37434.1 - 4.1e-17 62.5 0.0 9.7e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AET37434.1 - 9.1e-12 44.7 0.3 2.8e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 AET37434.1 - 2.2e-10 39.8 0.0 1.9e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AET37434.1 - 1.3e-05 24.6 0.0 2.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 AET37434.1 - 0.00036 20.2 0.2 0.0013 18.4 0.1 1.9 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain RimK PF08443.6 AET37434.1 - 0.0006 19.3 0.0 0.0045 16.4 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 AET37434.1 - 0.0018 18.1 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 AET37434.1 - 0.0022 17.6 0.3 0.25 11.0 0.0 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like Toxin_59 PF15537.1 AET37434.1 - 0.022 14.8 0.7 0.22 11.5 0.0 2.7 3 0 0 3 3 2 0 Putative toxin 59 AMP-binding PF00501.23 AET37435.1 - 6.2e-73 245.5 0.0 8.4e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Glutaredoxin PF00462.19 AET37436.1 - 1.4e-17 63.3 0.0 2.5e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Exo5 PF09810.4 AET37437.1 - 1.9e-29 102.9 0.1 2.3e-28 99.3 0.0 2.3 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 AET37437.1 - 1.4e-06 27.8 0.0 2.6e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 AET37437.1 - 0.00079 19.3 1.0 0.076 12.9 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function DUF83 UAA PF08449.6 AET37438.1 - 2.9e-19 69.1 21.9 3.5e-19 68.8 15.2 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 AET37438.1 - 1.2e-09 37.9 6.8 1.2e-09 37.9 4.7 2.9 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 AET37438.1 - 0.0011 18.9 25.7 0.066 13.2 7.2 2.5 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 AET37438.1 - 0.0043 16.1 2.9 0.0043 16.1 2.0 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter PHO4 PF01384.15 AET37438.1 - 0.011 14.3 1.4 0.011 14.3 0.9 2.6 2 1 0 2 2 2 0 Phosphate transporter family Multi_Drug_Res PF00893.14 AET37438.1 - 0.65 10.5 12.3 0.87 10.0 2.4 3.2 3 1 0 3 3 3 0 Small Multidrug Resistance protein Nse5 PF08691.5 AET37439.1 - 5.2e-26 91.2 15.5 6.4e-26 90.9 10.8 1.2 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 HAD_2 PF13419.1 AET37440.1 - 3.8e-24 85.8 0.0 5.2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AET37440.1 - 0.00014 22.3 0.0 0.0054 17.1 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 AET37440.1 - 0.14 11.8 0.0 12 5.5 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase Vps51 PF08700.6 AET37441.1 - 0.051 13.4 1.0 0.21 11.4 0.1 2.3 2 0 0 2 2 2 0 Vps51/Vps67 ABC_tran PF00005.22 AET37442.1 - 1.3e-49 167.9 0.0 1.1e-24 87.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 AET37442.1 - 5.9e-22 78.9 2.4 3.2e-06 27.3 0.0 4.4 2 2 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 AET37442.1 - 1.3e-21 76.2 1.2 1.3e-21 76.2 0.8 3.2 3 0 0 3 3 2 1 ABC transporter AAA_17 PF13207.1 AET37442.1 - 5.3e-10 40.1 0.2 0.00031 21.5 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 AET37442.1 - 4.6e-09 35.6 0.0 0.00075 18.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 AET37442.1 - 1.6e-08 34.7 0.1 0.0071 16.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 AET37442.1 - 2.2e-08 34.4 0.9 0.016 15.5 0.0 4.0 4 1 0 4 4 3 2 AAA domain SMC_N PF02463.14 AET37442.1 - 2.5e-08 33.4 7.5 0.67 9.1 0.0 5.4 4 1 1 6 6 6 4 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 AET37442.1 - 2.7e-07 29.8 0.0 0.00027 20.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 AET37442.1 - 2.9e-07 30.9 0.2 0.021 15.3 0.0 3.1 3 0 0 3 3 3 2 Miro-like protein AAA_33 PF13671.1 AET37442.1 - 6.1e-07 29.4 0.1 0.081 12.7 0.0 3.6 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 AET37442.1 - 8.8e-06 25.4 0.4 0.16 11.6 0.0 2.9 3 0 0 3 3 2 2 NACHT domain MMR_HSR1 PF01926.18 AET37442.1 - 1.2e-05 25.2 0.0 0.044 13.7 0.1 3.3 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 AET37442.1 - 2.5e-05 24.6 0.3 0.0059 16.9 0.0 4.3 3 2 0 4 4 3 2 AAA domain AAA_14 PF13173.1 AET37442.1 - 3.5e-05 23.6 0.1 0.69 9.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 AET37442.1 - 6e-05 23.1 1.0 0.6 10.0 0.0 3.3 4 0 0 4 4 2 2 AAA ATPase domain AAA_15 PF13175.1 AET37442.1 - 7.5e-05 21.9 0.0 0.33 9.9 0.0 3.4 4 1 0 4 4 3 2 AAA ATPase domain RNA_helicase PF00910.17 AET37442.1 - 7.9e-05 22.7 0.0 0.52 10.5 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 AET37442.1 - 8.4e-05 22.7 2.5 0.21 11.7 0.0 3.6 4 2 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 AET37442.1 - 0.00014 21.5 2.6 0.001 18.7 0.1 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 AET37442.1 - 0.00016 21.7 0.1 0.85 9.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 AET37442.1 - 0.00016 21.2 0.7 0.25 10.7 0.1 3.2 4 0 0 4 4 3 1 AAA-like domain MCM PF00493.18 AET37442.1 - 0.00039 19.3 1.3 0.28 9.9 0.0 2.9 3 0 0 3 3 3 2 MCM2/3/5 family AAA_25 PF13481.1 AET37442.1 - 0.00049 19.5 0.0 0.58 9.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 AET37442.1 - 0.00073 18.4 0.0 1.3 7.8 0.0 3.0 2 1 0 2 2 2 2 NB-ARC domain Arch_ATPase PF01637.13 AET37442.1 - 0.00097 18.9 2.1 0.69 9.5 0.0 3.2 4 0 0 4 4 3 1 Archaeal ATPase ArgK PF03308.11 AET37442.1 - 0.0011 17.8 0.0 0.14 10.9 0.0 2.7 3 0 0 3 3 3 1 ArgK protein DUF815 PF05673.8 AET37442.1 - 0.0013 17.6 0.3 1.6 7.5 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) VirE PF05272.6 AET37442.1 - 0.0018 17.8 0.1 0.66 9.4 0.0 2.9 3 0 0 3 3 3 1 Virulence-associated protein E AAA_5 PF07728.9 AET37442.1 - 0.0049 16.5 0.1 2 8.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 AET37442.1 - 0.0077 16.1 0.3 1.4 8.8 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 AET37442.1 - 0.011 15.4 0.1 1 9.0 0.0 2.6 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 AET37442.1 - 0.014 14.2 0.3 0.2 10.5 0.0 2.6 3 1 0 3 3 3 0 Type II/IV secretion system protein DAP3 PF10236.4 AET37442.1 - 0.016 14.1 0.6 5.2 5.9 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.10 AET37442.1 - 0.042 12.5 0.1 2.5 6.6 0.0 2.6 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein Dynamin_N PF00350.18 AET37442.1 - 0.044 13.6 5.0 4 7.2 0.0 3.9 4 1 1 5 5 5 0 Dynamin family FtsK_SpoIIIE PF01580.13 AET37442.1 - 0.052 13.0 0.0 2.2 7.6 0.0 2.8 2 1 1 3 3 3 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 AET37442.1 - 0.056 12.9 1.8 9.2 5.7 0.0 3.5 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 AET37442.1 - 0.074 12.6 0.5 14 5.3 0.0 3.2 2 1 1 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 FeoB_N PF02421.13 AET37442.1 - 0.093 11.9 0.0 2.8 7.1 0.0 2.6 3 0 0 3 3 2 0 Ferrous iron transport protein B DUF87 PF01935.12 AET37442.1 - 1.7 8.4 10.8 14 5.4 0.0 4.3 4 1 1 5 5 5 0 Domain of unknown function DUF87 BRF1 PF07741.8 AET37442.1 - 9.8 6.4 14.1 0.4 10.9 4.9 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain MCM_N PF14551.1 AET37444.1 - 0.021 15.3 0.5 0.033 14.6 0.3 1.4 1 0 0 1 1 1 0 MCM N-terminal domain NIF3 PF01784.13 AET37445.1 - 4.2e-63 213.1 0.5 5.1e-63 212.8 0.3 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 AET37446.1 - 1.3e-17 63.4 0.0 1.6e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Kinesin PF00225.18 AET37448.1 - 5.4e-112 373.7 0.3 9.8e-112 372.9 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 AET37448.1 - 0.068 13.0 0.1 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 AET37448.1 - 5 6.3 12.1 1.8 7.8 4.6 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Cyclin PF08613.6 AET37449.1 - 4e-05 24.0 0.0 7.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AET37449.1 - 0.0056 16.2 0.0 0.017 14.6 0.0 1.9 1 1 0 1 1 1 1 Cyclin, N-terminal domain TFIIA PF03153.8 AET37449.1 - 2.2 8.1 8.1 3.9 7.2 5.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 AET37450.1 - 3.9e-17 61.4 18.1 1.5e-06 27.8 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 AET37450.1 - 0.021 14.3 0.0 9 5.8 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 AET37450.1 - 0.024 12.4 0.1 0.11 10.3 0.0 1.8 2 0 0 2 2 2 0 IKI3 family PX PF00787.19 AET37451.1 - 1.4e-10 40.9 0.3 4e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 AET37451.1 - 3.5e-08 33.0 7.8 7.4e-08 31.9 5.4 1.6 1 0 0 1 1 1 1 SNARE domain COMP PF11598.3 AET37451.1 - 0.23 11.5 2.3 5.3 7.2 0.9 3.0 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein ATP_bind_3 PF01171.15 AET37452.1 - 1.5e-16 60.4 0.0 2.8e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 AET37452.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 AET37452.1 - 0.04 12.4 0.0 0.07 11.6 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase Ras PF00071.17 AET37454.1 - 1.7e-60 203.0 0.3 2e-60 202.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET37454.1 - 9e-20 71.3 0.0 1.5e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET37454.1 - 1.9e-13 50.0 0.0 2.6e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AET37454.1 - 1.8e-07 31.0 0.0 3.2e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AET37454.1 - 1.5e-05 24.5 0.1 4.9e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 AET37454.1 - 0.0002 20.5 0.4 0.00025 20.2 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 AET37454.1 - 0.00043 19.5 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 AET37454.1 - 0.00074 18.7 0.1 0.0018 17.4 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 AET37454.1 - 0.0026 16.9 0.0 0.0043 16.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 AET37454.1 - 0.0088 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 AET37454.1 - 0.014 15.5 0.1 0.025 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AET37454.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 AET37454.1 - 0.026 14.5 0.3 0.1 12.5 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain TraG_N PF07916.6 AET37454.1 - 0.052 11.9 0.1 0.063 11.7 0.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Septin PF00735.13 AET37454.1 - 0.059 12.3 0.0 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin SpoIIID PF12116.3 AET37454.1 - 0.069 13.0 0.0 3.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D ABC_tran PF00005.22 AET37454.1 - 0.075 13.3 0.5 0.11 12.7 0.3 1.6 1 1 0 1 1 1 0 ABC transporter DUF1128 PF06569.6 AET37454.1 - 0.12 12.0 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) CHZ PF09649.5 AET37455.1 - 2.5e-19 68.2 1.9 2.5e-19 68.2 1.3 4.1 4 1 0 4 4 4 1 Histone chaperone domain CHZ DUF591 PF04569.9 AET37455.1 - 0.061 13.3 0.7 0.061 13.3 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function Herpes_PAP PF03325.8 AET37455.1 - 6.7 6.1 9.6 7.6 5.9 6.7 1.2 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein LSM PF01423.17 AET37456.1 - 1.8e-15 56.2 0.0 2.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain CO_deh_flav_C PF03450.12 AET37456.1 - 0.033 14.1 0.5 0.054 13.4 0.3 1.4 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain AMPKBI PF04739.10 AET37457.1 - 1.2e-30 105.3 1.6 2.2e-30 104.5 1.1 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain AJAP1_PANP_C PF15298.1 AET37457.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus SPT16 PF08644.6 AET37458.1 - 1.1e-52 177.9 0.2 1.1e-52 177.9 0.2 2.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 AET37458.1 - 1.7e-45 154.4 0.6 7.2e-45 152.4 0.0 2.3 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 AET37458.1 - 2.4e-25 89.3 0.0 4.2e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 AET37458.1 - 3.9e-18 65.2 0.1 4.7e-17 61.7 0.1 2.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Clathrin PF00637.15 AET37459.1 - 4.1e-191 626.2 49.1 8.5e-33 112.9 0.0 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 AET37459.1 - 1.1e-25 89.3 2.4 2.4e-25 88.2 0.2 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 AET37459.1 - 8.2e-14 50.8 1.5 0.0012 18.9 0.1 5.9 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.5 AET37459.1 - 6.4e-08 31.4 3.6 8.4e-08 31.0 0.5 2.5 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_7 PF13176.1 AET37459.1 - 0.0047 16.6 7.9 17 5.4 0.0 7.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_12 PF13424.1 AET37459.1 - 0.055 13.4 11.1 6.5 6.7 0.2 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 AET37459.1 - 0.17 12.2 5.9 88 3.5 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 AET37459.1 - 0.23 11.5 4.2 28 4.9 0.1 4.6 3 1 1 4 4 4 0 PPR repeat TPR_1 PF00515.23 AET37459.1 - 0.25 11.0 10.2 57 3.5 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat ACOX PF01756.14 AET37461.1 - 1.9e-45 154.5 0.0 3.3e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 AET37461.1 - 7.2e-18 63.8 0.7 1.4e-17 62.8 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 AET37461.1 - 1.8e-09 37.9 0.0 4.2e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 AET37461.1 - 0.00018 21.6 0.0 0.0032 17.5 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SDH_beta PF03315.10 AET37461.1 - 0.066 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Serine dehydratase beta chain CDP-OH_P_transf PF01066.16 AET37462.1 - 2.7e-11 43.6 4.7 5.3e-11 42.7 3.3 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase She2p PF11435.3 AET37462.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding protein She2p Peptidase_S10 PF00450.17 AET37464.1 - 4.9e-104 348.7 0.0 6.2e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 AET37464.1 - 0.013 15.4 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Phosphorylase PF00343.15 AET37465.1 - 0 1018.2 0.1 0 1017.8 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate phosphorylase Striatin PF08232.7 AET37465.1 - 0.25 11.6 1.1 0.52 10.6 0.1 1.9 2 0 0 2 2 2 0 Striatin family MCM PF00493.18 AET37466.1 - 4.8e-139 462.7 0.9 7e-139 462.2 0.6 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AET37466.1 - 1.5e-19 70.6 3.0 3e-19 69.6 0.0 2.7 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AET37466.1 - 4.5e-07 29.2 0.0 1.5e-06 27.5 0.0 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AET37466.1 - 0.004 16.6 0.0 0.0081 15.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 AET37466.1 - 0.0071 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AET37466.1 - 0.011 15.4 0.0 0.051 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SKN1 PF03935.10 AET37467.1 - 2.1e-256 850.9 3.8 2.4e-256 850.6 2.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SIS PF01380.17 AET37468.1 - 1.6e-16 60.0 0.1 2.5e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 AET37468.1 - 6.8e-05 22.6 0.4 0.026 14.2 0.2 2.5 1 1 0 1 1 1 1 SIS domain Tir_receptor_C PF07489.6 AET37468.1 - 0.058 13.1 1.4 0.1 12.3 1.0 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus ABC2_membrane PF01061.19 AET37469.1 - 1.5e-48 164.7 57.3 4.5e-26 91.3 16.8 2.8 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 AET37469.1 - 3.9e-23 81.0 5.9 1.3e-16 60.0 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 AET37469.1 - 2.7e-12 47.1 0.1 1.5e-11 44.7 0.0 2.2 3 0 0 3 3 3 1 ABC transporter ABC2_membrane_3 PF12698.2 AET37469.1 - 1.1e-05 24.7 19.3 1.1e-05 24.7 13.4 3.2 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.1 AET37469.1 - 1.8e-05 24.8 5.1 9.7e-05 22.4 1.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 AET37469.1 - 8.2e-05 21.8 0.0 0.0057 15.7 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 AET37469.1 - 0.00035 20.9 0.2 0.00071 19.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 AET37469.1 - 0.00077 18.6 0.1 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 AET37469.1 - 0.0012 18.1 0.0 0.01 15.0 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AET37469.1 - 0.012 15.0 0.2 0.041 13.3 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 AET37469.1 - 0.017 15.1 0.1 0.044 13.7 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 AET37469.1 - 0.025 13.9 0.3 0.12 11.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 AET37469.1 - 0.033 14.3 0.2 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AET37469.1 - 0.045 14.0 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AET37469.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 AET37469.1 - 0.1 13.4 0.1 0.29 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AET37469.1 - 0.14 11.5 0.2 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain SRP1_TIP1 PF00660.12 AET37470.1 - 3e-26 91.2 0.0 4.5e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Seripauperin and TIP1 family Med3 PF11593.3 AET37470.1 - 0.86 8.7 5.0 0.98 8.5 3.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BASP1 PF05466.7 AET37470.1 - 1.3 8.8 14.3 1.7 8.3 9.9 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DEC-1_N PF04625.8 AET37470.1 - 2.7 6.5 7.8 3.6 6.1 5.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1517 PF07466.6 AET37470.1 - 3.8 6.4 7.2 5.5 5.9 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF946 PF06101.6 AET37472.1 - 5.3e-06 24.7 4.4 9.4e-06 23.8 3.0 1.5 1 1 0 1 1 1 1 Plant protein of unknown function (DUF946) GCR1_C PF12550.3 AET37473.1 - 3.2e-17 62.1 0.1 7.2e-17 61.0 0.1 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NCA2 PF08637.5 AET37474.1 - 3.8e-95 318.1 4.7 6e-95 317.4 3.3 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 SH3_1 PF00018.23 AET37475.1 - 9.6e-15 53.7 0.0 1.5e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AET37475.1 - 8.3e-14 50.9 0.0 1.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AET37475.1 - 8e-12 44.4 0.0 1.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 AET37475.1 - 5.4 6.3 19.2 1.4 8.1 11.3 1.5 2 0 0 2 2 2 0 Vta1 like Proteasome PF00227.21 AET37476.1 - 4.8e-59 198.8 0.3 5.8e-59 198.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AET37476.1 - 1.6e-13 49.6 0.3 4.1e-13 48.3 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2533 PF10752.4 AET37476.1 - 0.13 12.5 0.1 2.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) FF PF01846.14 AET37477.1 - 3.6e-10 39.6 1.8 3.6e-10 39.6 1.2 3.0 2 1 0 2 2 2 1 FF domain WW PF00397.21 AET37477.1 - 0.00053 19.7 2.8 0.0012 18.6 2.0 1.6 1 0 0 1 1 1 1 WW domain CENP-B_dimeris PF09026.5 AET37477.1 - 0.013 15.7 10.3 0.59 10.3 0.4 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 AET37477.1 - 1.9 7.9 15.9 5 6.6 3.2 2.6 2 0 0 2 2 2 0 Nucleoplasmin Vps39_1 PF10366.4 AET37477.1 - 2.4 8.2 7.2 0.39 10.7 1.2 2.3 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Pet20 PF08692.5 AET37479.1 - 2.7e-16 59.7 0.0 2.7e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet20 UQ_con PF00179.21 AET37480.1 - 5.2e-36 123.1 0.0 5.8e-36 123.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 AET37480.1 - 0.022 14.4 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 AET37480.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain Band_7 PF01145.20 AET37481.1 - 4.2e-24 85.4 4.8 6.1e-24 84.9 3.0 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family MARVEL PF01284.18 AET37482.1 - 1.6e-27 96.0 10.9 2e-27 95.7 7.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain SCAMP PF04144.8 AET37482.1 - 8 6.2 8.3 97 2.7 5.7 2.6 1 1 0 1 1 1 0 SCAMP family DUF3573 PF12097.3 AET37483.1 - 0.011 14.4 0.2 0.011 14.4 0.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3573) IFT20 PF14931.1 AET37483.1 - 2.1 8.2 24.8 2.4 8.0 6.6 3.4 1 1 3 4 4 4 0 Intraflagellar transport complex B, subunit 20 Vac_Fusion PF02346.11 AET37483.1 - 4.4 6.8 6.9 1.7 8.1 0.1 3.1 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Reo_sigmaC PF04582.7 AET37483.1 - 9.1 5.3 25.9 0.026 13.7 2.1 4.0 2 1 2 4 4 4 0 Reovirus sigma C capsid protein ATG16 PF08614.6 AET37483.1 - 9.4 6.0 40.8 3.8 7.2 21.6 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BAR_2 PF10455.4 AET37484.1 - 4.7e-95 317.8 12.4 4.7e-95 317.8 8.6 1.4 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SYF2 PF08231.7 AET37485.1 - 4.1e-11 43.2 10.3 9.5e-11 42.0 7.2 1.6 1 1 0 1 1 1 1 SYF2 splicing factor CCDC-167 PF15188.1 AET37485.1 - 3.8 7.5 6.3 0.53 10.2 0.5 2.5 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2305 PF10230.4 AET37486.1 - 7e-69 232.2 0.0 8e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 AET37486.1 - 3.4e-08 33.6 0.0 4.3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AET37486.1 - 0.00085 19.0 0.0 0.0016 18.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET37486.1 - 0.05 13.1 0.0 0.12 11.8 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold PAH PF02671.16 AET37486.1 - 0.34 10.5 1.5 18 5.0 0.1 3.0 3 0 0 3 3 3 0 Paired amphipathic helix repeat NRDE PF05742.7 AET37487.1 - 6.7e-52 176.4 0.1 8.4e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 NRDE protein Asn_synthase PF00733.16 AET37488.1 - 1.8e-69 234.1 0.0 2.4e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 AET37488.1 - 2.9e-33 114.2 0.0 5.2e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 AET37488.1 - 5e-26 91.2 0.0 5.2e-25 87.9 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 AET37488.1 - 7.5e-05 22.0 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 AET37488.1 - 0.0032 16.4 0.0 0.0071 15.2 0.0 1.6 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 AET37488.1 - 0.013 14.1 0.0 2.2 6.9 0.0 2.7 1 1 2 3 3 3 0 Glutamine amidotransferases class-II CBF PF03914.12 AET37489.1 - 4.9e-47 159.4 0.5 4.9e-47 159.4 0.3 1.9 2 0 0 2 2 2 1 CBF/Mak21 family CDP-OH_P_transf PF01066.16 AET37490.1 - 1.6e-18 66.8 5.7 1.8e-18 66.7 3.4 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Mito_carr PF00153.22 AET37491.1 - 2.6e-58 193.7 2.8 7e-23 80.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyt_c_ox_IV PF12270.3 AET37491.1 - 0.03 14.0 0.1 3.8 7.2 0.0 2.7 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV RNase_PH PF01138.16 AET37492.1 - 5.9e-14 52.5 0.0 2.1e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AET37492.1 - 0.0055 16.6 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 tRNA-synt_1 PF00133.17 AET37493.1 - 2.4e-228 759.0 0.0 2.4e-228 759.0 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AET37493.1 - 2.8e-31 108.3 0.6 2.8e-31 108.3 0.4 2.5 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AET37493.1 - 1.9e-16 59.7 6.0 2.9e-09 36.0 0.0 4.7 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 AET37493.1 - 9.6e-11 41.3 5.8 6.1e-07 28.9 0.0 3.4 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 AET37493.1 - 4.8e-05 23.3 5.6 4.8e-05 23.3 3.9 2.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 AET37493.1 - 0.29 10.1 0.0 0.29 10.1 0.0 3.4 4 1 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain LETM1 PF07766.8 AET37494.1 - 5.8e-100 333.7 3.5 9.6e-100 333.0 2.4 1.3 1 0 0 1 1 1 1 LETM1-like protein GPAT_N PF14829.1 AET37494.1 - 0.029 14.0 0.1 0.71 9.6 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal RNA_pol_3_Rpc31 PF11705.3 AET37494.1 - 3.5 7.5 13.9 12 5.7 5.0 2.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Ctr PF04145.10 AET37495.1 - 3e-26 92.1 0.3 6.2e-26 91.1 0.2 1.5 1 0 0 1 1 1 1 Ctr copper transporter family DUF4229 PF14012.1 AET37495.1 - 2 8.3 14.6 0.06 13.2 5.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DASH_Dam1 PF08653.5 AET37496.1 - 2.2e-28 97.7 0.5 2.2e-28 97.7 0.4 1.6 2 0 0 2 2 2 1 DASH complex subunit Dam1 MCPVI PF02993.9 AET37496.1 - 0.0039 17.3 3.7 0.0039 17.3 2.6 2.1 1 1 1 2 2 2 1 Minor capsid protein VI Paramyxo_C PF01692.13 AET37496.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.1 1 1 1 2 2 2 0 Paramyxovirus non-structural protein c Suppressor_APC PF11414.3 AET37496.1 - 0.17 11.6 0.4 0.6 9.9 0.1 2.0 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein SURF1 PF02104.10 AET37497.1 - 1.2e-59 201.7 0.0 1.9e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 SURF1 family Ribosomal_S5 PF00333.15 AET37498.1 - 2.3e-23 81.6 0.1 7.9e-23 79.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AET37498.1 - 1.7e-19 68.8 0.0 3.6e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain HMG_box PF00505.14 AET37499.1 - 9.8e-12 44.9 6.4 9.8e-12 44.9 4.4 2.8 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AET37499.1 - 5.9e-06 26.5 0.9 1.9e-05 24.9 0.6 1.9 1 0 0 1 1 1 1 HMG-box domain Enkurin PF13864.1 AET37499.1 - 1.8 8.7 11.3 0.29 11.3 0.6 2.6 2 0 0 2 2 2 0 Calmodulin-binding Peptidase_M41 PF01434.13 AET37500.1 - 7.6e-74 247.7 0.1 1.1e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AET37500.1 - 2e-41 141.2 0.0 6.3e-41 139.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 AET37500.1 - 1.7e-10 41.0 0.1 3.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 AET37500.1 - 0.0012 19.6 0.1 0.0076 17.0 0.0 2.5 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 AET37500.1 - 0.0078 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 AET37500.1 - 0.013 14.2 0.1 0.024 13.3 0.1 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 AET37500.1 - 0.017 14.8 0.1 0.076 12.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AET37500.1 - 0.024 14.7 0.9 0.49 10.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 AET37500.1 - 0.025 13.6 0.2 0.075 12.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 AET37500.1 - 0.037 13.7 1.7 0.061 13.0 0.5 1.9 2 0 0 2 2 2 0 Part of AAA domain CARD PF00619.16 AET37500.1 - 0.037 13.8 0.1 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain AAA_28 PF13521.1 AET37500.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AET37500.1 - 0.088 13.1 0.4 0.41 10.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.7 AET37500.1 - 0.12 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AET37500.1 - 0.19 11.1 1.1 0.62 9.4 0.4 2.1 2 1 1 3 3 3 0 AAA domain EB1 PF03271.12 AET37501.1 - 8.1e-18 64.2 0.6 1.8e-17 63.1 0.4 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 AET37501.1 - 1.9e-06 27.8 0.3 3.8e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF1202 PF06717.6 AET37501.1 - 0.00022 20.5 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1202) BRE1 PF08647.6 AET37501.1 - 0.026 14.4 0.1 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase SlyX PF04102.7 AET37501.1 - 0.43 10.9 1.6 0.55 10.6 0.3 1.8 2 0 0 2 2 2 0 SlyX GCR1_C PF12550.3 AET37502.1 - 2.1e-17 62.7 2.1 4.4e-17 61.7 1.4 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes RRM_5 PF13893.1 AET37503.1 - 5.9e-12 45.2 0.0 8e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET37503.1 - 1e-08 34.6 0.1 2e-08 33.7 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET37503.1 - 2.4e-07 30.6 0.0 4.5e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ubiquitin_2 PF14560.1 AET37503.1 - 0.033 14.4 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Limkain-b1 PF11608.3 AET37503.1 - 0.037 13.7 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 DAO PF01266.19 AET37504.1 - 1.5e-07 30.7 0.0 1.1e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AET37504.1 - 5.7e-07 29.4 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AET37504.1 - 9.2e-05 22.7 0.1 0.015 15.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 AET37504.1 - 0.0015 16.8 0.0 0.079 11.1 0.0 2.4 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 AET37504.1 - 0.0035 17.2 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AET37504.1 - 0.011 15.8 0.0 0.85 9.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AET37504.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 AET37504.1 - 0.02 14.6 0.0 0.93 9.2 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 AET37504.1 - 0.074 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HA2 PF04408.18 AET37505.1 - 8.7e-28 96.3 0.2 3.3e-27 94.4 0.0 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AET37505.1 - 2.4e-24 85.3 0.0 6.5e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AET37505.1 - 9.2e-13 47.8 0.0 3.3e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 AET37505.1 - 4.2e-11 42.7 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 AET37505.1 - 3.7e-06 26.5 0.1 8.6e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 AET37505.1 - 3.7e-05 22.7 0.1 0.00092 18.1 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 AET37505.1 - 4.3e-05 23.6 0.1 0.00019 21.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 AET37505.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 AET37505.1 - 0.002 17.9 0.6 0.35 10.6 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 AET37505.1 - 0.0021 16.9 0.0 0.0068 15.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 AET37505.1 - 0.0028 17.9 4.6 1.1 9.5 0.0 3.5 2 1 0 3 3 3 2 ABC transporter AAA_14 PF13173.1 AET37505.1 - 0.01 15.7 0.1 0.13 12.1 0.0 2.7 1 1 0 1 1 1 0 AAA domain PWI PF01480.12 AET37505.1 - 0.011 15.8 0.7 0.73 9.9 0.2 2.9 2 0 0 2 2 2 0 PWI domain SRP54 PF00448.17 AET37505.1 - 0.033 13.6 0.1 0.087 12.2 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Miro PF08477.8 AET37505.1 - 0.038 14.4 0.3 0.82 10.1 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 AET37505.1 - 0.051 13.0 0.1 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 AET37505.1 - 0.063 13.0 0.1 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 AET37505.1 - 0.94 9.7 0.0 0.94 9.7 0.0 3.9 4 1 0 4 4 3 0 AAA domain Proteasome PF00227.21 AET37506.1 - 2.8e-40 137.6 0.0 3.2e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DNA_primase_S PF01896.14 AET37507.1 - 3e-53 179.5 1.3 5.5e-53 178.6 0.9 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Cellulase PF00150.13 AET37508.1 - 2.2e-10 40.2 2.9 3.3e-05 23.2 0.9 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) LETM1 PF07766.8 AET37509.1 - 1.2e-102 342.5 7.5 1.9e-102 341.9 5.2 1.3 1 0 0 1 1 1 1 LETM1-like protein DUF1746 PF08508.5 AET37510.1 - 0.29 11.0 5.4 0.62 10.0 3.7 1.6 1 1 0 1 1 1 0 Fungal domain of unknown function (DUF1746) Rpr2 PF04032.11 AET37511.1 - 5.3e-18 64.6 1.6 7.1e-18 64.2 1.1 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Rhabdo_matrix PF03397.9 AET37511.1 - 0.036 13.4 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein zf-CSL PF05207.8 AET37511.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 CSL zinc finger Med16 PF11635.3 AET37511.1 - 0.13 10.2 0.5 0.15 9.9 0.3 1.0 1 0 0 1 1 1 0 Mediator complex subunit 16 TOM13 PF08219.6 AET37512.1 - 5.2e-27 93.4 0.2 1.1e-26 92.3 0.0 1.6 1 1 1 2 2 2 1 Outer membrane protein TOM13 Proteasome PF00227.21 AET37513.1 - 2.8e-56 189.8 0.0 3.6e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AET37513.1 - 1.2e-12 46.8 0.9 1.6e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature APC_CDC26 PF10471.4 AET37513.1 - 1.4 9.6 5.2 3 8.6 3.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 RNA_pol_Rpb1_3 PF04983.13 AET37514.1 - 0.003 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 bZIP_2 PF07716.10 AET37515.1 - 0.00017 21.3 11.9 0.00017 21.3 8.2 3.1 3 1 1 4 4 4 2 Basic region leucine zipper bZIP_1 PF00170.16 AET37515.1 - 0.016 15.1 14.2 0.039 13.9 7.6 2.6 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 AET37515.1 - 5.3 6.5 6.9 5.3 6.5 3.0 2.1 2 0 0 2 2 2 0 IncA protein Pkinase PF00069.20 AET37516.1 - 8.4e-72 241.4 0.0 1.3e-71 240.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37516.1 - 2.5e-42 144.7 0.0 3.5e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET37516.1 - 0.0039 16.1 0.0 0.02 13.8 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 AET37516.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AET37516.1 - 0.068 12.5 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF4074 PF13293.1 AET37516.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4074) Glycogen_syn PF05693.8 AET37517.1 - 0 1084.0 0.0 0 1083.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 AET37517.1 - 2e-09 37.1 0.0 3.2e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AET37517.1 - 4e-06 27.0 0.4 8.9e-06 25.9 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 AET37517.1 - 6.3e-05 22.5 0.1 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain SH3BGR PF04908.10 AET37519.1 - 0.0013 18.6 0.0 0.0053 16.6 0.0 2.1 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 AET37519.1 - 0.041 13.8 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin Citrate_synt PF00285.16 AET37520.1 - 7.3e-101 337.4 0.0 8.6e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Cupin_8 PF13621.1 AET37521.1 - 5e-12 45.8 0.1 1.4e-11 44.4 0.1 1.7 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 AET37521.1 - 2.7e-11 43.7 0.3 9.8e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase F-box-like PF12937.2 AET37521.1 - 0.00046 19.8 1.7 0.00073 19.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like Elongin_A PF06881.6 AET37521.1 - 0.0028 18.0 0.5 0.0028 18.0 0.4 2.2 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Cupin_2 PF07883.6 AET37521.1 - 0.016 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ribosomal_L32p PF01783.18 AET37522.1 - 4.9e-11 42.6 7.0 7.6e-11 42.0 4.8 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family CpXC PF14353.1 AET37522.1 - 0.01 15.7 1.3 0.016 15.1 0.8 1.4 1 1 0 1 1 1 0 CpXC protein RecR PF02132.10 AET37522.1 - 0.026 13.9 0.3 0.045 13.1 0.2 1.4 1 0 0 1 1 1 0 RecR protein DUF2930 PF11152.3 AET37522.1 - 0.095 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) Septin PF00735.13 AET37523.1 - 5.9e-106 353.6 2.0 6.9e-106 353.3 1.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AET37523.1 - 1.2e-09 38.1 0.2 1.9e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AET37523.1 - 1.1e-07 31.4 0.7 3.9e-06 26.4 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 AET37523.1 - 1.3e-06 27.7 0.6 4.1e-06 26.0 0.4 1.9 1 1 0 1 1 1 1 AIG1 family DUF258 PF03193.11 AET37523.1 - 2.1e-06 27.0 0.0 3.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AET37523.1 - 4.5e-06 26.5 1.8 0.0065 16.3 0.4 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 AET37523.1 - 0.00079 19.9 0.8 0.0018 18.7 0.2 1.9 1 1 1 2 2 2 1 Miro-like protein AAA_16 PF13191.1 AET37523.1 - 0.00099 19.1 0.1 0.0035 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AET37523.1 - 0.0015 18.4 0.4 0.035 13.9 0.6 2.8 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AET37523.1 - 0.0022 17.4 0.1 0.004 16.6 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 AET37523.1 - 0.0031 17.8 1.2 0.007 16.6 0.6 1.8 1 1 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 AET37523.1 - 0.0048 16.4 0.1 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 AET37523.1 - 0.0085 16.4 0.3 0.015 15.6 0.2 1.5 1 1 0 1 1 1 1 AAA domain IIGP PF05049.8 AET37523.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 AET37523.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AET37523.1 - 0.014 14.9 0.3 0.028 14.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AET37523.1 - 0.016 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 AET37523.1 - 0.025 14.2 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 AET37523.1 - 0.036 13.9 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AET37523.1 - 0.043 13.2 0.1 0.98 8.9 0.0 2.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 AET37523.1 - 0.044 13.1 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 AET37523.1 - 0.049 12.4 0.4 0.079 11.7 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 AET37523.1 - 0.078 13.1 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_17 PF13207.1 AET37523.1 - 0.13 13.0 0.3 0.27 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain eRF1_2 PF03464.10 AET37524.1 - 1.4e-29 103.1 0.0 2.1e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AET37524.1 - 7.9e-27 93.7 0.1 2.3e-25 89.0 0.0 2.4 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 AET37524.1 - 7.9e-16 57.8 0.0 1.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Peroxin-22 PF12827.2 AET37524.1 - 0.057 13.1 0.3 0.26 10.9 0.1 2.2 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family DUF2778 PF10908.3 AET37524.1 - 0.096 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) Rer1 PF03248.8 AET37525.1 - 1.8e-76 255.6 8.5 2.1e-76 255.4 5.9 1.0 1 0 0 1 1 1 1 Rer1 family DUF4191 PF13829.1 AET37525.1 - 0.03 13.4 0.6 3.4 6.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4400 PF14348.1 AET37525.1 - 0.054 12.8 5.7 0.16 11.3 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) CitMHS PF03600.11 AET37525.1 - 0.077 11.5 0.6 0.092 11.2 0.4 1.1 1 0 0 1 1 1 0 Citrate transporter Selenoprotein_S PF06936.6 AET37525.1 - 0.086 12.3 0.4 0.78 9.2 0.0 2.0 1 1 1 2 2 2 0 Selenoprotein S (SelS) DUF2208 PF09973.4 AET37525.1 - 2.3 7.3 6.6 0.67 9.1 1.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) PLDc_2 PF13091.1 AET37526.1 - 1.1e-15 57.4 0.0 1.9e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AET37526.1 - 3.9e-12 45.5 0.5 1.2e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif ATP_synt_H PF05493.8 AET37528.1 - 5.1e-22 77.7 4.9 5.7e-22 77.5 3.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H MgtE PF01769.11 AET37528.1 - 0.0053 17.0 1.7 0.0055 16.9 1.2 1.0 1 0 0 1 1 1 1 Divalent cation transporter Cyt_c_ox_IV PF12270.3 AET37528.1 - 0.029 14.1 0.8 0.031 14.0 0.5 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV 7TM-7TMR_HD PF07698.6 AET37528.1 - 0.032 13.6 3.2 0.035 13.5 2.2 1.0 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF3624 PF12292.3 AET37528.1 - 0.045 14.1 3.9 0.089 13.2 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3624) AzlD PF05437.7 AET37528.1 - 0.046 13.6 4.1 0.051 13.5 0.1 2.1 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Git3 PF11710.3 AET37528.1 - 0.077 12.5 1.1 0.078 12.5 0.7 1.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 GWT1 PF06423.7 AET37528.1 - 0.078 13.0 1.5 0.098 12.7 1.0 1.1 1 0 0 1 1 1 0 GWT1 DUF3112 PF11309.3 AET37528.1 - 0.12 12.1 1.6 0.12 12.1 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) YfhO PF09586.5 AET37528.1 - 0.18 9.7 1.7 0.19 9.6 1.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4131 PF13567.1 AET37528.1 - 0.26 10.6 1.1 0.27 10.6 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2721 PF11026.3 AET37528.1 - 5.7 6.5 6.7 6.5 6.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Internalin_N PF12354.3 AET37528.1 - 8.6 6.0 6.2 5 6.8 0.9 2.0 1 1 1 2 2 2 0 Bacterial adhesion/invasion protein N terminal UEV PF05743.8 AET37529.1 - 2.3e-24 85.3 0.1 9.1e-24 83.4 0.0 2.0 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 AET37529.1 - 9.7e-24 82.7 0.3 1.7e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 Vps23 core domain Fib_alpha PF08702.5 AET37529.1 - 1.5 8.9 4.4 0.9 9.6 1.6 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DKCLD PF08068.7 AET37530.1 - 9.7e-30 102.2 0.2 3.7e-29 100.4 0.1 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 AET37530.1 - 6.3e-23 81.5 1.7 2.8e-20 72.9 0.0 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 AET37530.1 - 3.1e-20 71.6 1.3 7.2e-20 70.4 0.9 1.7 1 0 0 1 1 1 1 PUA domain DUF4139 PF13598.1 AET37530.1 - 0.00074 18.9 0.4 0.001 18.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) CTDII PF01556.13 AET37531.1 - 2e-25 88.5 0.2 1.3e-21 76.3 0.0 2.5 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 AET37531.1 - 1.3e-23 82.4 0.3 2.2e-23 81.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 AET37532.1 - 2e-50 166.9 18.1 3.6e-12 45.6 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 AET37532.1 - 1.9e-10 39.5 11.5 0.0086 14.2 0.1 5.0 1 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AET37532.1 - 2.5e-06 26.5 1.6 0.2 10.3 0.1 4.0 1 1 3 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 AET37532.1 - 3.3e-05 22.3 0.0 0.00015 20.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Coatomer_WDAD PF04053.9 AET37532.1 - 0.024 13.4 0.0 0.073 11.8 0.0 1.6 1 1 0 2 2 2 0 Coatomer WD associated region Ribosomal_L30 PF00327.15 AET37533.1 - 5.8e-14 51.4 1.9 8.3e-14 50.9 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_viral_C PF00336.13 AET37533.1 - 0.098 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Iso_dh PF00180.15 AET37534.1 - 6.2e-128 426.6 0.0 7.2e-128 426.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_5 PF00266.14 AET37535.1 - 3.6e-99 332.0 0.0 4.4e-99 331.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AET37535.1 - 1.1e-08 34.5 0.2 1e-07 31.3 0.0 2.4 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 AET37535.1 - 1.4e-08 34.2 0.0 2.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 AET37535.1 - 0.027 12.9 0.1 0.039 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain TraT PF05818.7 AET37535.1 - 0.049 13.0 0.1 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Mito_carr PF00153.22 AET37536.1 - 4.1e-53 177.0 3.6 2.5e-21 75.1 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2036 PF09724.4 AET37537.1 - 2.2e-83 280.1 0.0 2.5e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF3507 PF12015.3 AET37538.1 - 1.1e-63 214.0 0.0 2.1e-63 213.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2015 PF09435.5 AET37539.1 - 1.5e-39 134.7 0.1 1.6e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) VirD1 PF07328.6 AET37539.1 - 0.014 15.2 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 SPK PF04435.13 AET37539.1 - 0.13 12.2 0.3 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF545) DUF3687 PF12459.3 AET37539.1 - 0.16 11.2 0.3 0.27 10.4 0.2 1.4 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein RRM_1 PF00076.17 AET37540.1 - 2.4e-42 142.4 0.1 2.8e-17 62.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET37540.1 - 2.4e-22 78.7 0.0 4.1e-09 36.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET37540.1 - 2.8e-10 39.8 0.2 2.2e-06 27.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1325 PF07039.6 AET37541.1 - 9.3e-36 122.3 0.0 1.6e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.7 AET37541.1 - 0.0081 16.2 0.1 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Agenet domain DUF4537 PF15057.1 AET37541.1 - 0.029 14.1 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Ribosomal_L27 PF01016.14 AET37542.1 - 9.6e-31 105.4 0.0 1.7e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein ALS_ss_C PF10369.4 AET37543.1 - 4.6e-19 67.9 0.0 4.9e-18 64.6 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 AET37543.1 - 6.5e-09 35.0 0.0 1.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 AET37543.1 - 1.3e-06 28.0 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain Iso_dh PF00180.15 AET37544.1 - 1e-69 235.1 0.0 1.2e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAD PF12710.2 AET37545.1 - 5.4e-12 46.2 0.3 7.2e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 AET37545.1 - 3.1e-09 36.3 0.5 4.5e-09 35.8 0.3 1.2 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 AET37545.1 - 6.3e-08 32.2 0.0 7.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 AET37545.1 - 0.071 13.5 0.0 9.6 6.5 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UPF0052 PF01933.13 AET37546.1 - 6.1e-59 199.8 0.0 8e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF3842 PF12953.2 AET37546.1 - 0.0026 17.9 0.1 0.0049 17.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3842) EF-hand_6 PF13405.1 AET37547.1 - 8.7e-05 22.0 3.0 0.025 14.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 AET37547.1 - 0.00019 21.4 1.8 0.00019 21.4 1.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AET37547.1 - 0.00044 19.3 4.0 0.039 13.2 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 AET37547.1 - 0.026 14.1 2.5 0.091 12.3 0.9 2.4 2 1 0 2 2 2 0 EF-hand domain pair Polyhedrin PF00738.13 AET37547.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Polyhedrin PLA2_B PF01735.13 AET37549.1 - 4.1e-86 289.0 3.7 5.7e-80 268.8 0.5 2.1 2 0 0 2 2 2 2 Lysophospholipase catalytic domain AstB PF04996.7 AET37549.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase ABC_tran PF00005.22 AET37550.1 - 6.9e-44 149.4 0.0 6.9e-23 81.4 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AET37550.1 - 1e-17 65.0 0.2 0.0017 18.3 0.0 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 AET37550.1 - 3.2e-15 55.9 0.0 5e-06 25.9 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AET37550.1 - 2.8e-09 36.3 0.0 0.003 17.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AET37550.1 - 3.8e-09 37.1 2.8 0.0017 18.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 AET37550.1 - 3e-08 34.5 0.0 0.003 18.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AET37550.1 - 3.4e-08 32.8 0.0 0.00046 19.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AET37550.1 - 3.5e-08 33.6 0.0 0.002 18.2 0.0 4.1 4 1 0 4 4 3 2 AAA domain Dynamin_N PF00350.18 AET37550.1 - 2.7e-07 30.5 0.0 1.5e-05 24.9 0.0 2.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 AET37550.1 - 4.7e-07 29.7 0.2 0.0054 16.6 0.0 3.2 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 AET37550.1 - 1.4e-06 28.3 0.0 0.008 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AET37550.1 - 2e-06 27.7 0.0 0.074 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AET37550.1 - 4e-06 27.1 0.0 0.016 15.5 0.0 3.4 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 AET37550.1 - 4.3e-06 25.7 0.0 0.063 12.0 0.0 2.5 2 0 0 2 2 2 2 ArgK protein SbcCD_C PF13558.1 AET37550.1 - 4.5e-06 26.4 0.0 0.0095 15.8 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 AET37550.1 - 5.4e-06 26.6 0.0 0.53 10.4 0.0 4.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AET37550.1 - 5.6e-06 26.0 0.1 0.24 10.8 0.0 3.4 4 0 0 4 4 4 2 AAA-like domain AAA_15 PF13175.1 AET37550.1 - 5.8e-06 25.6 0.0 0.75 8.7 0.0 4.3 3 1 1 4 4 4 1 AAA ATPase domain HEAT_2 PF13646.1 AET37550.1 - 5.9e-06 26.4 0.8 0.013 15.8 0.0 3.4 1 1 2 3 3 3 2 HEAT repeats Miro PF08477.8 AET37550.1 - 6.1e-06 26.7 0.0 0.045 14.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein RNA_helicase PF00910.17 AET37550.1 - 9.7e-06 25.7 0.0 0.11 12.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 AET37550.1 - 7.5e-05 22.4 0.0 0.33 10.6 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 AET37550.1 - 0.00011 22.2 0.3 0.28 11.1 0.0 3.9 5 0 0 5 5 3 1 AAA ATPase domain AAA_13 PF13166.1 AET37550.1 - 0.00011 20.8 2.0 2.5 6.4 0.0 4.0 3 1 1 4 4 4 2 AAA domain Arch_ATPase PF01637.13 AET37550.1 - 0.00015 21.5 0.0 0.33 10.5 0.0 3.2 3 0 0 3 3 2 1 Archaeal ATPase MutS_V PF00488.16 AET37550.1 - 0.00034 20.0 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 1 MutS domain V DUF87 PF01935.12 AET37550.1 - 0.00068 19.5 0.8 0.3 10.8 0.0 3.6 4 0 0 4 4 3 1 Domain of unknown function DUF87 CLASP_N PF12348.3 AET37550.1 - 0.00069 19.0 0.6 0.56 9.5 0.0 2.9 2 1 0 3 3 3 1 CLASP N terminal AAA_14 PF13173.1 AET37550.1 - 0.00088 19.1 0.0 2.9 7.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 AET37550.1 - 0.00094 18.8 0.0 0.75 9.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain MMS19_C PF12460.3 AET37550.1 - 0.00097 17.9 0.8 0.38 9.4 0.0 3.1 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal AAA_30 PF13604.1 AET37550.1 - 0.0033 17.0 0.1 3.9 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 AET37550.1 - 0.0038 16.7 0.0 0.32 10.4 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ParcG PF10274.4 AET37550.1 - 0.005 16.7 0.3 3.1 7.6 0.0 3.0 2 1 0 3 3 3 0 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 AET37550.1 - 0.0096 16.2 0.1 2.2 8.7 0.0 3.4 3 1 1 5 5 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 AET37550.1 - 0.013 15.4 1.1 22 5.4 0.0 4.7 5 0 0 5 5 3 0 HEAT repeat HEAT_EZ PF13513.1 AET37550.1 - 0.014 15.8 5.9 10 6.7 0.0 4.9 4 2 2 6 6 5 0 HEAT-like repeat Zeta_toxin PF06414.7 AET37550.1 - 0.015 14.4 0.2 3 6.8 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin cobW PF02492.14 AET37550.1 - 0.017 14.5 3.4 1.4 8.3 0.0 3.2 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 AET37550.1 - 0.02 14.0 0.1 1.1 8.3 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 AET37550.1 - 0.021 13.7 0.0 0.48 9.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.1 AET37550.1 - 0.024 14.0 0.0 12 5.2 0.0 3.3 3 0 0 3 3 2 0 AAA domain UME PF08064.8 AET37550.1 - 0.035 14.0 0.3 0.19 11.6 0.1 2.2 1 1 1 2 2 2 0 UME (NUC010) domain Cnd1 PF12717.2 AET37550.1 - 0.038 13.8 0.1 0.5 10.2 0.0 2.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 AET37550.1 - 0.046 12.0 5.6 0.72 8.1 0.9 2.9 1 1 1 3 3 3 0 Adaptin N terminal region FtsK_SpoIIIE PF01580.13 AET37550.1 - 0.052 13.0 0.4 3 7.2 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 AET37550.1 - 0.054 12.9 0.0 12 5.2 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Septin PF00735.13 AET37550.1 - 0.057 12.4 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_19 PF13245.1 AET37550.1 - 0.075 12.7 0.1 5.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain DUF3385 PF11865.3 AET37550.1 - 0.076 12.9 0.2 4.9 7.0 0.1 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF3385) ATP_bind_1 PF03029.12 AET37550.1 - 0.082 12.4 1.1 7.8 5.9 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Pkinase PF00069.20 AET37551.1 - 3.1e-36 124.8 0.0 4.5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37551.1 - 6.4e-11 41.8 0.0 1.2e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET37551.1 - 0.0015 17.5 0.1 0.041 12.8 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Sugar_tr PF00083.19 AET37552.1 - 5.1e-175 582.3 33.8 5.8e-175 582.1 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET37552.1 - 2e-35 122.1 39.3 2.1e-28 99.0 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_1d PF00750.14 AET37553.1 - 1.1e-104 350.0 6.4 1.4e-104 349.7 4.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 AET37553.1 - 1.2e-30 105.8 0.1 4.1e-29 100.9 0.0 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 AET37553.1 - 1.1e-05 25.8 0.0 3.5e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Sugar_tr PF00083.19 AET37554.1 - 3.4e-175 582.9 35.4 3.9e-175 582.7 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET37554.1 - 5.6e-36 123.9 44.1 1.4e-28 99.6 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Svf1 PF08622.5 AET37555.1 - 7.5e-130 432.6 1.3 8.7e-130 432.4 0.9 1.0 1 0 0 1 1 1 1 Svf1-like Sod_Fe_C PF02777.13 AET37556.1 - 1.2e-10 41.2 0.9 0.00046 19.9 0.0 2.4 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Pal1 PF08316.6 AET37557.1 - 8.2e-55 185.0 1.7 2.3e-54 183.6 1.2 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein Sec23_trunk PF04811.10 AET37558.1 - 4.9e-55 186.5 0.0 9.2e-55 185.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AET37558.1 - 1.6e-19 69.1 0.6 4.4e-19 67.8 0.4 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AET37558.1 - 1.8e-13 50.8 0.0 3.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AET37558.1 - 1.8e-13 49.8 6.9 3.5e-13 48.8 4.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AET37558.1 - 1.8e-05 24.3 0.3 0.00012 21.6 0.0 2.4 3 0 0 3 3 3 1 Gelsolin repeat Asp PF00026.18 AET37559.1 - 6.9e-25 87.9 0.7 2.5e-24 86.1 0.5 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease FAT PF02259.18 AET37560.1 - 1.8e-71 240.9 8.3 3.8e-71 239.9 5.7 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 AET37560.1 - 1.7e-41 142.2 4.0 2.2e-41 141.8 0.7 2.9 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 AET37560.1 - 1.8e-07 30.4 0.1 6e-07 28.7 0.0 2.0 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 AET37560.1 - 0.0066 16.0 5.0 0.076 12.6 0.5 3.4 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 AET37560.1 - 0.038 13.9 2.1 0.9 9.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PGP_phosphatase PF09419.5 AET37561.1 - 2e-66 222.4 0.0 2.3e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 AET37561.1 - 3.8e-05 23.3 0.0 6.3e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AET37561.1 - 0.034 14.5 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.1 AET37562.1 - 8.4e-09 34.9 6.3 8.4e-09 34.9 4.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AET37562.1 - 0.004 16.7 9.4 0.004 16.7 6.5 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET37562.1 - 0.011 15.7 8.8 0.011 15.7 6.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Pex2_Pex12 PF04757.9 AET37563.1 - 1.5e-33 116.1 4.5 1.9e-33 115.7 3.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 AET37563.1 - 3.8e-08 33.2 18.0 7e-08 32.3 12.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET37563.1 - 6.3e-08 32.3 18.0 1e-07 31.6 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AET37563.1 - 4.6e-06 26.2 18.8 7.1e-06 25.5 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AET37563.1 - 1.3e-05 24.6 16.1 2.4e-05 23.8 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET37563.1 - 3.1e-05 23.6 13.3 5.9e-05 22.7 9.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AET37563.1 - 0.005 16.6 16.9 0.01 15.7 11.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 AET37563.1 - 0.012 15.6 12.4 0.024 14.7 8.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 AET37563.1 - 0.016 14.9 12.3 0.079 12.6 7.9 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 AET37563.1 - 0.88 9.3 11.3 1.8 8.4 7.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein UNC45-central PF11701.3 AET37564.1 - 1.4e-20 73.5 7.4 7.7e-20 71.1 1.2 2.9 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central Ank_2 PF12796.2 AET37565.1 - 3e-46 155.6 0.1 4.1e-17 62.2 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 AET37565.1 - 1.4e-34 116.1 0.5 2.4e-07 30.2 0.0 6.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 AET37565.1 - 3.1e-26 88.7 0.6 0.00075 19.5 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 AET37565.1 - 4.9e-26 90.1 0.2 1.3e-07 31.5 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 AET37565.1 - 3.3e-23 81.6 0.5 4.5e-08 33.3 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) zf-DHHC PF01529.15 AET37565.1 - 1.3e-22 80.0 4.3 1.3e-22 80.0 3.0 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase XPG_N PF00752.12 AET37566.1 - 1.6e-24 86.1 0.0 3.2e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 AET37566.1 - 1.8e-21 76.0 0.0 4.3e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 AET37566.1 - 0.0003 20.9 0.0 0.0028 17.8 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 AET37566.1 - 0.0077 16.0 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif Sugar_tr PF00083.19 AET37567.1 - 1.7e-53 181.8 23.6 1.8e-52 178.4 16.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET37567.1 - 3e-17 62.3 41.0 1.5e-08 33.7 14.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF606 PF04657.8 AET37567.1 - 0.0088 16.1 4.1 0.0088 16.1 2.9 3.5 3 1 0 3 3 3 1 Protein of unknown function, DUF606 HLH PF00010.21 AET37568.1 - 6.9e-20 70.5 0.5 1.4e-19 69.4 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Fasciclin PF02469.17 AET37569.1 - 8.5e-07 29.0 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain PDCD2_C PF04194.8 AET37570.1 - 4.9e-40 136.8 0.7 4.5e-38 130.4 0.0 2.9 2 1 1 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain Argos PF11581.3 AET37570.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos GTP_EFTU PF00009.22 AET37571.1 - 3.2e-33 114.7 5.8 2.8e-32 111.6 4.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AET37571.1 - 5.6e-23 80.9 0.0 1.7e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.10 AET37571.1 - 1.3e-07 31.1 0.0 3.4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 AET37571.1 - 1.9e-06 28.3 0.7 3e-05 24.4 0.2 2.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU_D2 PF03144.20 AET37571.1 - 3.3e-06 27.1 1.7 0.00079 19.4 0.0 3.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AET37571.1 - 5.6e-06 26.2 2.8 1.5e-05 24.8 0.4 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 AET37571.1 - 0.014 14.8 1.7 0.054 12.9 1.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 AET37571.1 - 0.016 14.5 1.6 0.018 14.4 0.3 1.7 2 0 0 2 2 2 0 Ras family Dynamin_N PF00350.18 AET37571.1 - 0.033 14.0 3.1 6 6.6 0.2 3.3 2 1 1 3 3 3 0 Dynamin family TauD PF02668.11 AET37572.1 - 2.7e-39 135.4 0.0 3.8e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 AET37572.1 - 8.6e-06 26.0 0.0 0.0077 16.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.5 AET37572.1 - 0.0079 15.1 0.0 2.4 6.9 0.0 2.2 2 0 0 2 2 2 2 CsiD Presenilin PF01080.12 AET37573.1 - 1.4 7.6 5.5 0.68 8.6 2.7 1.3 1 1 0 1 1 1 0 Presenilin DUF2893 PF11459.3 AET37574.1 - 0.064 13.0 0.0 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) PGK PF00162.14 AET37575.1 - 6.4e-153 508.8 0.1 7.3e-153 508.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DNA_pol_B_palm PF14792.1 AET37576.1 - 2.9e-15 56.2 0.0 9e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 AET37576.1 - 1.7e-14 53.2 0.0 4e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 AET37576.1 - 1.6e-11 43.5 0.2 3.5e-11 42.4 0.2 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 AET37576.1 - 5.6e-11 42.4 0.0 1.5e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 AET37576.1 - 0.0017 18.6 0.0 0.0065 16.7 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain BRCT PF00533.21 AET37576.1 - 0.094 12.8 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HAD PF12710.2 AET37577.1 - 1.2e-09 38.6 0.0 1.6e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 AET37577.1 - 0.16 11.1 0.4 3 6.9 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase DUF2373 PF10180.4 AET37578.1 - 8.5e-22 76.4 0.0 1.7e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Sugar_tr PF00083.19 AET37579.1 - 1.4e-102 343.5 28.1 1.9e-102 343.1 19.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET37579.1 - 2e-24 85.9 30.7 1.9e-23 82.7 15.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.4 AET37580.1 - 7.4e-33 113.8 9.9 7.4e-33 113.8 6.8 3.9 4 2 0 4 4 4 1 Frag1/DRAM/Sfk1 family SieB PF14163.1 AET37580.1 - 0.13 11.8 5.0 0.44 10.1 0.1 2.8 2 0 0 2 2 2 0 Superinfection exclusion protein B Alpha-amylase_C PF02806.13 AET37581.1 - 2.9e-25 88.2 0.1 8e-25 86.8 0.1 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 AET37581.1 - 1.3e-18 67.4 0.3 1.5e-17 64.0 0.1 2.4 2 1 0 2 2 2 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 AET37581.1 - 2.6e-13 49.7 0.2 9.3e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 AET37581.1 - 0.0015 17.0 0.0 0.0026 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 UQ_con PF00179.21 AET37582.1 - 5.2e-39 132.8 0.1 6.8e-39 132.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AET37582.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.7 1 1 0 1 1 1 0 RWD domain HOOK PF05622.7 AET37583.1 - 0.0061 14.4 0.8 0.0064 14.3 0.5 1.0 1 0 0 1 1 1 1 HOOK protein Snurportin1 PF11538.3 AET37583.1 - 0.13 12.0 1.1 0.24 11.1 0.8 1.6 1 0 0 1 1 1 0 Snurportin1 LSM PF01423.17 AET37584.1 - 3.6e-07 29.6 0.3 5.8e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 LSM domain IPT PF01745.11 AET37584.1 - 0.1 11.7 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase PfkB PF00294.19 AET37585.1 - 2.5e-06 26.8 0.0 3.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Arm PF00514.18 AET37586.1 - 1.2e-67 221.6 31.5 8.2e-12 44.4 0.0 10.9 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AET37586.1 - 9.7e-26 89.8 8.8 2.1e-06 27.9 0.1 7.0 3 3 3 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 AET37586.1 - 7.5e-18 64.4 15.6 3e-05 24.3 0.2 7.5 6 2 2 8 8 7 5 HEAT-like repeat HEAT PF02985.17 AET37586.1 - 1.9e-15 55.4 21.8 0.025 14.6 0.1 9.7 10 0 0 10 10 10 4 HEAT repeat Adaptin_N PF01602.15 AET37586.1 - 4.3e-13 48.4 9.3 2.8e-08 32.5 2.4 2.3 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 AET37586.1 - 6.2e-11 41.8 9.1 3e-07 29.8 2.7 3.5 3 1 0 3 3 3 2 Armadillo-like KAP PF05804.7 AET37586.1 - 2.2e-08 32.5 1.5 2.2e-08 32.5 1.1 2.5 2 1 0 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 AET37586.1 - 7.4e-06 25.3 5.9 0.0074 15.4 0.2 3.6 1 1 2 3 3 3 3 V-ATPase subunit H DUF2454 PF10521.4 AET37586.1 - 1.3e-05 24.3 0.3 0.047 12.6 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF2454) Cnd1 PF12717.2 AET37586.1 - 0.00025 20.9 3.7 0.43 10.4 0.0 4.6 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 AET37586.1 - 0.00031 21.0 0.5 0.85 10.0 0.0 3.7 2 1 0 3 3 2 2 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 AET37586.1 - 0.0034 17.3 4.2 0.16 11.8 0.1 4.4 3 2 1 4 4 4 1 V-ATPase subunit H DUF1981 PF09324.5 AET37586.1 - 0.0081 15.6 0.3 15 5.1 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1981) Phage_30_3 PF08010.6 AET37586.1 - 0.095 12.1 0.0 0.28 10.6 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 YjeF_N PF03853.10 AET37587.1 - 3.2e-27 95.1 0.0 5.3e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 AET37587.1 - 6.7e-06 26.5 7.7 6.7e-06 26.5 5.4 2.5 1 1 1 2 2 2 1 FDF domain Phosphodiest PF01663.17 AET37588.1 - 1.7e-48 165.8 0.5 2.4e-48 165.3 0.4 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4573 PF15140.1 AET37588.1 - 0.00011 21.8 23.7 0.00043 19.9 16.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) SR-25 PF10500.4 AET37589.1 - 0.017 14.6 13.6 0.023 14.1 9.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3256 PF11644.3 AET37590.1 - 0.001 18.6 0.8 0.0016 18.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3256) DUF87 PF01935.12 AET37590.1 - 0.061 13.1 1.4 0.085 12.6 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 zf-Nse PF11789.3 AET37591.1 - 1.1e-18 66.5 0.1 2.1e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 AET37591.1 - 9.6e-08 31.6 0.5 3e-07 30.0 0.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 AET37591.1 - 6.8e-05 22.7 0.1 0.00025 20.9 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-RING_2 PF13639.1 AET37591.1 - 0.00018 21.2 0.3 0.00035 20.3 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AET37591.1 - 0.0014 18.5 0.4 0.0027 17.7 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 AET37591.1 - 0.0033 16.9 0.4 0.0061 16.0 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Rtf2 PF04641.7 AET37591.1 - 0.0041 16.3 0.1 0.0041 16.3 0.1 1.5 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 AET37591.1 - 0.011 15.4 0.1 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AET37591.1 - 0.038 14.0 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 AET37591.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger tRNA-synt_2 PF00152.15 AET37592.1 - 1e-71 241.5 0.0 1.3e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AET37592.1 - 7.1e-08 32.1 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AET37592.1 - 0.022 13.9 0.0 0.9 8.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) TPP_enzyme_N PF02776.13 AET37593.1 - 4.7e-37 127.1 0.0 7.7e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AET37593.1 - 1e-23 83.5 0.0 2.2e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AET37593.1 - 3.7e-23 81.7 0.9 1.4e-22 79.8 0.2 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 AET37593.1 - 0.064 12.1 0.1 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase zf-Tim10_DDP PF02953.10 AET37595.1 - 1e-21 75.9 6.1 1.5e-21 75.4 4.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pepsin-I3 PF06394.8 AET37595.1 - 0.056 13.1 1.8 0.57 9.8 0.1 2.1 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Gemini_AL1_M PF08283.6 AET37595.1 - 0.085 12.6 0.2 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Geminivirus rep protein central domain Mmp37 PF09139.6 AET37595.1 - 0.091 11.7 0.3 0.096 11.6 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Ku_PK_bind PF08785.6 AET37595.1 - 0.17 11.7 2.6 0.21 11.4 1.8 1.1 1 0 0 1 1 1 0 Ku C terminal domain like DUF842 PF05811.8 AET37595.1 - 0.3 10.5 8.2 0.69 9.3 5.7 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Vicilin_N PF04702.7 AET37595.1 - 0.76 9.3 6.4 1.1 8.8 4.4 1.2 1 0 0 1 1 1 0 Vicilin N terminal region OMPdecase PF00215.19 AET37596.1 - 8.2e-74 247.8 0.0 9.6e-74 247.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mito_carr PF00153.22 AET37597.1 - 2.8e-11 42.9 2.4 3.2e-08 33.1 0.1 3.7 4 1 0 4 4 4 2 Mitochondrial carrier protein Sec7 PF01369.15 AET37598.1 - 2.8e-63 213.0 1.1 2.8e-63 213.0 0.8 1.8 2 0 0 2 2 2 1 Sec7 domain DivIVA PF05103.8 AET37598.1 - 0.065 13.2 3.6 0.17 11.9 2.5 1.6 1 0 0 1 1 1 0 DivIVA protein Pro_isomerase PF00160.16 AET37599.1 - 8.8e-40 136.4 0.2 1.5e-39 135.6 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 AET37599.1 - 3.3e-12 45.8 4.2 1.2e-05 24.8 0.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AET37599.1 - 7.6e-09 34.8 14.5 1.4e-08 33.9 2.7 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 AET37599.1 - 1.7e-08 33.7 11.9 4.7e-06 26.1 1.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AET37599.1 - 9.3e-07 28.6 2.7 1.5e-05 24.8 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AET37599.1 - 0.00078 19.0 2.1 0.00078 19.0 1.5 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 AET37599.1 - 0.031 14.9 0.2 0.19 12.4 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 AET37599.1 - 0.059 13.8 1.3 0.19 12.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 AET37599.1 - 0.37 11.1 0.1 0.37 11.1 0.1 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Rav1p_C PF12234.3 AET37600.1 - 2.1e-241 802.5 11.1 3.8e-241 801.7 7.7 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 AET37600.1 - 0.012 15.5 7.3 0.63 10.0 0.1 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Pet191_N PF10203.4 AET37601.1 - 1e-26 92.7 3.9 1.5e-26 92.2 2.7 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 AET37601.1 - 0.021 14.6 2.9 0.62 9.8 0.1 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like SNF2_N PF00176.18 AET37602.1 - 5.1e-76 255.3 0.4 5.1e-76 255.3 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AET37602.1 - 5e-14 51.9 0.0 3.9e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UvsW PF11637.3 AET37602.1 - 0.0065 16.1 9.1 0.018 14.7 0.2 4.2 4 0 0 4 4 4 2 ATP-dependant DNA helicase UvsW AAA_11 PF13086.1 AET37602.1 - 0.51 9.8 0.0 0.51 9.8 0.0 3.6 3 1 0 4 4 4 0 AAA domain DUF2235 PF09994.4 AET37603.1 - 1.7e-83 280.1 0.0 2.5e-83 279.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) UCR_TM PF02921.9 AET37604.1 - 4.8e-23 81.1 2.2 9.9e-23 80.1 1.6 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 AET37604.1 - 8.3e-18 63.7 0.0 1.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF2516 PF10724.4 AET37604.1 - 0.06 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) Transp_cyt_pur PF02133.10 AET37604.1 - 0.1 11.1 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin HECT PF00632.20 AET37605.1 - 5e-88 295.2 5.3 2.7e-87 292.8 0.3 2.6 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) Ribosomal_L7Ae PF01248.21 AET37608.1 - 1.3e-27 95.1 0.0 1.5e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AET37608.1 - 0.01 15.6 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 AET37608.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Voltage_CLC PF00654.15 AET37609.1 - 2e-80 270.5 20.7 2e-80 270.5 14.3 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 AET37609.1 - 3.1e-10 39.6 0.0 3.2e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain Urb2 PF10441.4 AET37610.1 - 2.6e-61 207.1 3.9 2.6e-61 207.1 2.7 2.6 3 0 0 3 3 3 1 Urb2/Npa2 family Nucleopor_Nup85 PF07575.8 AET37611.1 - 5.5e-168 559.7 12.4 6.4e-168 559.4 8.6 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin ATP-synt_C PF00137.16 AET37612.1 - 4.8e-31 106.4 29.7 1.3e-18 66.6 7.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 AET37612.1 - 0.32 10.6 7.3 0.16 11.6 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) CDC27 PF09507.5 AET37613.1 - 0.016 14.4 34.1 0.01 15.1 20.9 2.4 2 1 0 2 2 2 0 DNA polymerase subunit Cdc27 CTK3_C PF12350.3 AET37613.1 - 0.064 13.2 5.6 0.2 11.7 3.9 1.9 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus Phage_GPO PF05929.6 AET37613.1 - 0.18 11.0 5.6 0.27 10.4 3.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-C2H2 PF00096.21 AET37614.1 - 1.4e-06 28.2 9.1 0.0075 16.5 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET37614.1 - 0.00017 21.7 0.2 0.00017 21.7 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET37614.1 - 0.0027 17.9 13.3 0.063 13.6 2.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger Nipped-B_C PF12830.2 AET37614.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Hus1 PF04005.7 AET37614.1 - 0.047 12.6 1.0 0.072 12.0 0.7 1.3 1 0 0 1 1 1 0 Hus1-like protein zf-C2H2_jaz PF12171.3 AET37614.1 - 0.11 12.7 3.0 0.15 12.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AET37614.1 - 0.59 10.4 5.1 0.7 10.1 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type F-box-like PF12937.2 AET37615.1 - 9.9e-11 41.1 0.2 2.1e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AET37615.1 - 1.4e-09 37.3 0.2 3.2e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain Thg1 PF04446.7 AET37615.1 - 0.033 13.8 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 tRNAHis guanylyltransferase FAD_binding_6 PF00970.19 AET37616.1 - 1.8e-24 85.7 0.0 2.7e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AET37616.1 - 1.1e-23 83.9 0.0 1.8e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AET37616.1 - 5.4e-06 26.3 0.0 0.0002 21.3 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF4131 PF13567.1 AET37616.1 - 0.054 12.9 0.2 0.11 11.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) FAD_binding_9 PF08021.6 AET37616.1 - 0.067 13.1 0.0 0.22 11.4 0.0 1.9 1 1 1 2 2 2 0 Siderophore-interacting FAD-binding domain DNA_pol3_a_NII PF11490.3 AET37616.1 - 0.096 12.3 0.1 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II ALO PF04030.9 AET37617.1 - 1.5e-103 345.8 2.1 1.6e-103 345.8 0.6 1.6 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 AET37617.1 - 4e-28 97.6 0.0 6.1e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SIS_2 PF13580.1 AET37617.1 - 0.019 14.6 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 SIS domain BBE PF08031.7 AET37617.1 - 0.026 14.4 0.3 0.093 12.6 0.1 2.0 2 0 0 2 2 2 0 Berberine and berberine like Tubulin PF00091.20 AET37618.1 - 1.2e-69 234.4 0.0 1.9e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AET37618.1 - 1.1e-48 164.3 0.1 1.8e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Sugar_tr PF00083.19 AET37619.1 - 1.2e-41 142.7 20.0 1.7e-41 142.3 13.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET37619.1 - 2.4e-20 72.5 15.8 2e-11 43.2 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DMA PF03474.9 AET37619.1 - 0.13 12.1 0.2 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 DMRTA motif SQS_PSY PF00494.14 AET37620.1 - 1.8e-38 132.4 0.0 2.5e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase CppA_C PF14507.1 AET37620.1 - 0.071 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 CppA C-terminal Pept_tRNA_hydro PF01195.14 AET37621.1 - 4.3e-40 137.1 0.0 5.2e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Gtr1_RagA PF04670.7 AET37622.1 - 6e-95 316.7 4.4 8.9e-95 316.2 1.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.17 AET37622.1 - 4.5e-09 35.9 0.1 8e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 AET37622.1 - 2.2e-08 33.5 0.8 3.7e-08 32.8 0.0 1.8 2 1 1 3 3 3 1 ADP-ribosylation factor family Miro PF08477.8 AET37622.1 - 3e-07 30.9 0.2 7.6e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 AET37622.1 - 3.3e-06 27.0 0.0 8.9e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AET37622.1 - 0.005 17.1 0.3 0.012 15.9 0.1 1.9 2 1 0 2 2 2 1 ABC transporter SopD PF11047.3 AET37622.1 - 0.013 14.5 0.8 0.024 13.5 0.6 1.4 1 0 0 1 1 1 0 Salmonella outer protein D AIG1 PF04548.11 AET37622.1 - 0.027 13.5 0.7 0.28 10.2 0.1 2.3 1 1 1 2 2 2 0 AIG1 family AAA_29 PF13555.1 AET37622.1 - 0.033 13.7 0.1 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 AET37622.1 - 0.033 13.1 0.2 0.066 12.1 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) DUF258 PF03193.11 AET37622.1 - 0.073 12.2 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HNH_3 PF13392.1 AET37622.1 - 0.12 11.7 0.1 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease Guanylate_kin PF00625.16 AET37622.1 - 0.12 11.7 4.6 0.32 10.3 0.6 2.9 2 1 0 2 2 2 0 Guanylate kinase Pyr_redox_2 PF07992.9 AET37623.1 - 1.3e-26 93.7 1.9 3.4e-19 69.5 0.0 3.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AET37623.1 - 1.1e-13 51.3 0.1 1.7e-10 41.1 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AET37623.1 - 1.6e-09 38.1 0.0 0.00015 21.9 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_3 PF12000.3 AET37623.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group RRM_1 PF00076.17 AET37624.1 - 4.5e-07 29.4 0.2 1.3e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET37624.1 - 2.3e-06 27.3 0.2 1.2e-05 25.0 0.3 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET37624.1 - 0.0024 17.8 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AET37624.1 - 0.005 16.5 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AET37624.1 - 0.54 10.1 3.5 0.42 10.4 0.1 2.2 1 1 0 1 1 1 0 RNA binding motif DEAD PF00270.24 AET37625.1 - 2.7e-47 160.4 0.7 6.4e-44 149.4 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AET37625.1 - 2.2e-28 97.9 0.1 5.2e-28 96.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET37625.1 - 0.0005 19.9 0.3 0.0021 17.9 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Tyr-DNA_phospho PF06087.7 AET37625.1 - 0.008 14.8 0.1 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Helicase_C_4 PF13871.1 AET37625.1 - 0.053 12.9 0.1 0.23 10.8 0.1 2.0 1 1 0 1 1 1 0 Helicase_C-like TPR_11 PF13414.1 AET37626.1 - 6.9e-23 80.0 11.5 3e-09 36.4 1.3 4.1 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 AET37626.1 - 2.5e-19 68.0 2.5 5.5e-06 25.7 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 AET37626.1 - 9.3e-17 59.5 4.5 7.3e-05 22.3 0.1 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 AET37626.1 - 3.4e-13 49.8 0.7 0.0001 22.8 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AET37626.1 - 3.9e-12 45.6 1.4 0.0018 18.7 0.1 5.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 AET37626.1 - 2e-10 40.0 1.6 0.11 12.7 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 AET37626.1 - 1.4e-09 38.1 2.4 0.0085 16.4 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 AET37626.1 - 1.5e-08 34.6 0.6 0.0056 16.7 0.1 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AET37626.1 - 1.3e-06 27.7 0.7 0.29 11.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 AET37626.1 - 2.9e-06 27.0 0.5 0.0095 15.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AET37626.1 - 1.8e-05 24.6 5.3 0.0032 17.3 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 AET37626.1 - 0.00031 20.3 0.1 1.4 8.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 AET37626.1 - 0.0049 15.9 1.1 0.39 9.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 AET37626.1 - 0.0072 16.7 0.6 41 4.9 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 AET37626.1 - 0.21 11.8 0.1 0.21 11.8 0.0 2.3 2 1 1 3 3 2 0 Bacterial transcriptional activator domain Glyco_transf_34 PF05637.7 AET37627.1 - 4.2e-75 252.3 0.0 5e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 AET37627.1 - 0.043 13.1 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF273 ARID PF01388.16 AET37628.1 - 1.7e-20 72.6 0.1 7.8e-20 70.5 0.1 2.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain MTHFR PF02219.12 AET37629.1 - 4.6e-102 340.9 0.0 6.3e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF4612 PF15389.1 AET37629.1 - 0.026 15.1 0.1 0.061 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) Sybindin PF04099.7 AET37631.1 - 3.2e-38 130.6 0.2 6.6e-24 84.2 0.1 2.1 2 0 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.8 AET37631.1 - 1.4e-09 37.9 0.0 2.9e-09 36.8 0.0 1.5 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Serglycin PF04360.7 AET37631.1 - 0.073 12.7 0.6 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Serglycin FRQ PF09421.5 AET37631.1 - 0.32 8.7 3.1 0.39 8.4 2.2 1.1 1 0 0 1 1 1 0 Frequency clock protein DUF3020 PF11223.3 AET37632.1 - 7.2e-16 58.3 5.4 7.2e-16 58.3 3.7 8.9 8 2 1 9 9 9 1 Protein of unknown function (DUF3020) zf-H2C2_2 PF13465.1 AET37633.1 - 0.00017 21.7 13.5 0.0019 18.3 0.9 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 AET37633.1 - 0.0007 19.7 1.7 0.0007 19.7 1.2 4.3 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET37633.1 - 0.0019 18.3 20.1 0.013 15.8 0.7 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AET37633.1 - 0.023 14.8 11.1 0.46 10.6 0.9 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 AET37633.1 - 0.031 14.0 0.8 0.031 14.0 0.6 3.0 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.1 AET37633.1 - 0.11 12.4 5.1 2.3 8.2 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger TPT PF03151.11 AET37634.1 - 7.3e-38 129.6 9.5 7.3e-38 129.6 6.6 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AET37634.1 - 2.8e-16 59.3 13.9 2.8e-15 56.0 9.6 2.1 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 AET37634.1 - 1.8e-06 27.2 0.7 0.03 13.4 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 AET37634.1 - 3.5e-05 23.8 28.4 0.0012 18.8 7.7 3.2 2 2 1 3 3 3 2 EamA-like transporter family UPF0546 PF10639.4 AET37634.1 - 0.00019 21.2 8.6 0.31 10.8 0.1 3.4 3 0 0 3 3 3 2 Uncharacterised protein family UPF0546 EmrE PF13536.1 AET37634.1 - 0.0039 17.3 19.8 0.0049 17.0 0.3 3.1 3 1 1 4 4 4 2 Multidrug resistance efflux transporter MRP-L28 PF09812.4 AET37635.1 - 3e-40 137.5 2.8 3.7e-40 137.3 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Nop25 PF09805.4 AET37635.1 - 0.0034 17.4 0.3 0.0052 16.8 0.2 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) DUF413 PF04219.7 AET37635.1 - 0.044 13.5 0.3 0.062 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF FYRC PF05965.9 AET37635.1 - 0.14 11.9 0.4 0.33 10.7 0.1 1.7 2 0 0 2 2 2 0 F/Y rich C-terminus Ras PF00071.17 AET37636.1 - 1.9e-50 170.3 0.0 2.4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET37636.1 - 3.6e-19 69.3 0.0 5.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET37636.1 - 6.6e-09 35.2 0.1 8e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AET37636.1 - 5.4e-07 29.2 0.0 1e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AET37636.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AET37636.1 - 0.096 12.8 0.4 1 9.5 0.2 2.3 1 1 0 1 1 1 0 AAA domain Gly_transf_sug PF04488.10 AET37637.1 - 1.3e-12 48.0 0.0 3.2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 AET37637.1 - 0.032 12.7 0.1 0.38 9.1 0.0 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Isochorismatase PF00857.15 AET37638.1 - 3e-22 79.3 0.0 4.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family NUC153 PF08159.7 AET37640.1 - 4.5e-13 48.5 4.6 8.5e-13 47.6 3.2 1.5 1 0 0 1 1 1 1 NUC153 domain SNARE PF05739.14 AET37641.1 - 0.0038 16.8 2.5 0.0038 16.8 1.7 4.5 4 2 0 4 4 4 2 SNARE domain Ecl1 PF12855.2 AET37642.1 - 1.6e-14 52.8 1.1 3.5e-14 51.8 0.7 1.6 1 0 0 1 1 1 1 Life-span regulatory factor DUF2544 PF11245.3 AET37642.1 - 0.018 14.3 0.3 0.022 14.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) zf-MYND PF01753.13 AET37642.1 - 0.019 14.7 2.2 0.047 13.5 1.5 1.7 1 0 0 1 1 1 0 MYND finger zf-C2H2 PF00096.21 AET37643.1 - 3.9e-09 36.3 10.6 0.00045 20.4 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET37643.1 - 4.4e-07 29.8 17.5 5e-06 26.5 1.3 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET37643.1 - 1.3e-06 28.3 9.8 0.0042 17.3 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger PDGF_N PF04692.8 AET37643.1 - 0.9 10.0 6.8 0.13 12.7 1.0 2.4 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region TBPIP PF07106.8 AET37646.1 - 6.8e-50 168.9 8.3 8.2e-50 168.6 5.7 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ku_PK_bind PF08785.6 AET37646.1 - 0.0046 16.8 2.9 0.069 13.0 0.1 2.7 2 1 1 3 3 3 1 Ku C terminal domain like HsbA PF12296.3 AET37646.1 - 0.025 14.4 0.2 0.94 9.3 0.0 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A IncA PF04156.9 AET37646.1 - 0.029 13.9 2.3 0.031 13.8 1.6 1.2 1 0 0 1 1 1 0 IncA protein Fcf2 PF08698.6 AET37646.1 - 0.033 14.1 1.7 0.068 13.1 1.2 1.5 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing Phasin PF05597.6 AET37646.1 - 0.14 11.9 3.4 0.15 11.8 1.2 1.8 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Mnd1 PF03962.10 AET37646.1 - 0.22 11.1 7.7 0.8 9.3 5.3 2.0 1 1 0 1 1 1 0 Mnd1 family AAA_13 PF13166.1 AET37646.1 - 0.22 9.9 7.3 0.076 11.4 3.0 1.6 1 1 1 2 2 2 0 AAA domain TMPIT PF07851.8 AET37646.1 - 0.24 10.4 2.3 0.33 9.9 1.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.17 AET37646.1 - 0.71 9.9 11.5 0.11 12.5 3.9 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1279 PF06916.8 AET37647.1 - 3.4e-25 88.1 0.0 5.4e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SCFA_trans PF02667.9 AET37647.1 - 0.13 11.0 0.1 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter Ribosomal_L24e PF01246.15 AET37649.1 - 2.9e-34 116.7 0.4 2.9e-34 116.7 0.2 2.3 2 1 0 2 2 2 1 Ribosomal protein L24e PVL_ORF50 PF07768.6 AET37649.1 - 1.2 9.1 10.9 1.5 8.7 7.6 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family RR_TM4-6 PF06459.7 AET37649.1 - 4.9 6.9 9.0 5.9 6.7 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L7Ae PF01248.21 AET37650.1 - 4.1e-25 87.1 0.1 4.6e-25 86.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2838 PF10998.3 AET37651.1 - 4.2e-41 139.2 14.2 4.2e-41 139.2 9.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) MbeD_MobD PF04899.7 AET37651.1 - 0.037 13.9 0.3 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 MbeD/MobD like PPR_2 PF13041.1 AET37652.1 - 5e-14 52.0 1.4 1.6e-08 34.3 0.1 4.1 2 2 2 4 4 4 2 PPR repeat family PPR_3 PF13812.1 AET37652.1 - 6e-08 32.3 2.1 0.08 13.2 0.0 5.0 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 AET37652.1 - 0.00012 21.7 4.9 0.00024 20.8 0.1 4.0 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.2 AET37652.1 - 0.003 17.0 0.4 0.023 14.1 0.1 2.5 2 0 0 2 2 2 1 PPR repeat Cgr1 PF03879.9 AET37653.1 - 8e-38 128.9 29.8 9.3e-38 128.7 20.7 1.0 1 0 0 1 1 1 1 Cgr1 family DRY_EERY PF09750.4 AET37653.1 - 0.039 14.0 6.2 0.044 13.8 4.3 1.1 1 0 0 1 1 1 0 Alternative splicing regulator Type_III_YscX PF09474.5 AET37653.1 - 0.21 11.6 2.8 0.27 11.2 1.9 1.2 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) DUF342 PF03961.8 AET37653.1 - 0.33 9.3 12.2 0.35 9.2 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PRP1_N PF06424.7 AET37653.1 - 1 9.6 11.3 1.3 9.3 7.9 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Peptidase_S49_N PF08496.5 AET37653.1 - 8 6.2 13.1 11 5.7 9.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF706 PF05153.10 AET37654.1 - 1.5e-121 404.5 7.4 2.2e-121 403.9 5.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 AET37654.1 - 0.037 14.0 2.7 0.45 10.5 0.2 3.0 1 1 1 2 2 2 0 HD domain Glyco_hydro_63 PF03200.11 AET37655.1 - 6.3e-210 699.0 6.9 4.5e-209 696.2 4.8 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trp_syntA PF00290.15 AET37656.1 - 5.9e-89 297.0 0.1 9e-89 296.4 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 AET37656.1 - 2.5e-46 158.3 0.3 5.2e-46 157.2 0.2 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 AET37656.1 - 0.058 12.6 0.3 0.18 11.0 0.1 1.8 3 0 0 3 3 3 0 PcrB family Med3 PF11593.3 AET37657.1 - 4.8e-77 259.7 27.8 2e-74 251.1 19.3 2.1 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal DUF3867 PF12983.2 AET37657.1 - 0.05 13.5 0.1 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) zf-C4H2 PF10146.4 AET37657.1 - 2.2 8.2 8.1 9.4 6.1 5.6 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein PCI_Csn8 PF10075.4 AET37658.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 YfiO PF13525.1 AET37658.1 - 0.052 13.0 0.1 0.21 11.0 0.1 1.9 2 0 0 2 2 2 0 Outer membrane lipoprotein DUF1654 PF07867.6 AET37658.1 - 0.074 12.4 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) TPR_18 PF13512.1 AET37658.1 - 0.12 12.3 0.4 0.7 9.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Formyl_trans_N PF00551.14 AET37659.1 - 1.6e-30 106.0 0.1 2.8e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 AET37659.1 - 6.8e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Acyltransferase PF01553.16 AET37660.1 - 8.1e-10 38.2 0.0 4.8e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase FYVE PF01363.16 AET37661.1 - 8.3e-15 54.4 6.1 1.5e-14 53.6 4.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 AET37661.1 - 2.7 7.9 12.8 6.8 6.6 8.8 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger STT3 PF02516.9 AET37662.1 - 7.3e-135 450.6 43.7 5.7e-132 441.0 29.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Hamartin PF04388.7 AET37662.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Hamartin protein DUF3635 PF12330.3 AET37663.1 - 1.8e-11 43.9 1.2 8.5e-11 41.7 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 AET37663.1 - 0.00013 21.2 0.1 0.00025 20.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Telomerase_RBD PF12009.3 AET37664.1 - 1.4e-29 102.7 1.5 1.4e-29 102.7 1.0 2.4 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 AET37664.1 - 1.8e-10 40.5 1.6 6.5e-10 38.7 0.2 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AIP3 PF03915.8 AET37665.1 - 6.7e-153 509.5 11.2 6.7e-153 509.5 7.8 2.4 2 1 0 2 2 2 1 Actin interacting protein 3 PMC2NT PF08066.7 AET37665.1 - 0.0074 16.5 2.5 0.077 13.3 1.6 2.9 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HSBP1 PF06825.7 AET37665.1 - 0.039 13.5 1.3 0.11 12.1 0.1 2.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 FliL PF03748.9 AET37665.1 - 0.2 11.6 6.1 0.28 11.1 0.1 3.5 4 0 0 4 4 4 0 Flagellar basal body-associated protein FliL Mus7 PF09462.5 AET37666.1 - 2.2e-41 142.4 20.8 1.5e-27 96.7 4.5 3.1 2 1 1 3 3 3 2 Mus7/MMS22 family Myb_DNA-bind_6 PF13921.1 AET37667.1 - 8.9 6.5 8.7 0.82 9.8 0.3 3.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain Cullin PF00888.17 AET37668.1 - 2.4e-101 340.1 13.3 2.4e-101 340.1 9.2 1.6 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 AET37668.1 - 1.1e-17 63.5 2.9 4.3e-17 61.6 2.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain zf-CCCH PF00642.19 AET37669.1 - 6.2e-10 38.5 3.0 1.5e-09 37.2 2.0 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 AET37669.1 - 7.1e-09 35.1 7.8 1.3e-08 34.3 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET37669.1 - 5.4e-08 32.7 10.5 5.4e-08 32.7 7.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET37669.1 - 2e-07 30.7 6.0 5.2e-07 29.3 4.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AET37669.1 - 3e-07 30.0 11.2 6e-07 29.0 7.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AET37669.1 - 1.4e-06 27.8 11.8 1.4e-06 27.8 8.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AET37669.1 - 0.00021 20.9 6.4 0.00029 20.5 1.9 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AET37669.1 - 0.0044 16.8 9.7 0.0044 16.8 6.8 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 AET37669.1 - 0.0059 16.1 3.6 0.014 14.9 2.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 AET37669.1 - 0.0072 16.0 1.5 0.014 15.1 1.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein PolC_DP2 PF03833.8 AET37669.1 - 0.026 12.2 3.5 0.034 11.8 2.4 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-P11 PF03854.9 AET37669.1 - 0.12 11.8 5.2 0.28 10.6 3.6 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-rbx1 PF12678.2 AET37669.1 - 2.1 8.4 11.9 2.2 8.4 6.4 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger Pex24p PF06398.6 AET37670.1 - 2.6e-94 315.9 8.8 3.4e-94 315.6 6.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_L38e PF01781.13 AET37671.1 - 1.9e-26 91.6 3.8 2.1e-26 91.4 2.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF1395 PF07160.7 AET37671.1 - 0.047 13.1 0.2 0.06 12.8 0.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1395) TFIIF_beta PF02270.10 AET37672.1 - 1e-93 314.1 18.6 1.7e-93 313.4 12.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Prp18 PF02840.10 AET37673.1 - 8e-35 119.7 0.1 1.8e-34 118.6 0.0 1.5 1 1 0 1 1 1 1 Prp18 domain CTP_transf_2 PF01467.21 AET37674.1 - 1e-18 67.8 0.2 3.5e-13 49.9 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase HABP4_PAI-RBP1 PF04774.10 AET37675.1 - 1.5e-05 25.4 0.1 1.6e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RE_LlaJI PF09563.5 AET37675.1 - 0.018 13.7 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 LlaJI restriction endonuclease DnaJ PF00226.26 AET37676.1 - 1.1e-25 89.0 4.0 2.3e-25 88.0 2.7 1.6 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 AET37676.1 - 2.6e-23 81.7 0.4 1.3e-17 63.4 0.1 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AET37676.1 - 4e-11 42.8 19.7 7.7e-11 41.8 13.7 1.5 1 0 0 1 1 1 1 DnaJ central domain Antiterm PF03589.8 AET37676.1 - 0.12 12.4 8.7 12 6.0 1.3 3.7 1 1 2 3 3 3 0 Antitermination protein DUF3006 PF11213.3 AET37676.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) HypA PF01155.14 AET37676.1 - 2 8.1 8.4 0.21 11.2 1.3 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 AET37676.1 - 6.1 7.2 9.4 20 5.6 6.6 1.8 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 AET37676.1 - 8.8 6.0 13.0 31 4.2 9.1 1.9 1 1 0 1 1 1 0 Cytochrome c7 DUF2781 PF10914.3 AET37677.1 - 5.2e-25 87.9 9.7 8.3e-25 87.3 6.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) Acetyltransf_1 PF00583.19 AET37679.1 - 1.1e-14 54.2 0.0 1.6e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AET37679.1 - 8.1e-10 38.7 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AET37679.1 - 0.00039 20.2 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AET37679.1 - 0.0042 17.1 0.0 0.0054 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain JmjN PF02375.12 AET37679.1 - 0.068 12.6 0.4 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 jmjN domain MadL PF03817.8 AET37679.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 Malonate transporter MadL subunit LSM PF01423.17 AET37680.1 - 1e-15 56.9 0.1 1.2e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain Mannitol_dh_C PF08125.8 AET37680.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain Pyr_redox_dim PF02852.17 AET37681.1 - 3.8e-42 142.7 0.1 1.3e-41 141.0 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 AET37681.1 - 3.5e-36 124.9 12.8 4.4e-35 121.3 8.9 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AET37681.1 - 2.2e-20 72.8 5.4 1.3e-17 63.9 0.4 3.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AET37681.1 - 8.9e-12 44.8 0.9 4.1e-05 23.5 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 AET37681.1 - 1.6e-11 43.9 3.3 2.6e-10 39.9 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 AET37681.1 - 1.8e-09 36.9 7.8 4e-08 32.5 2.6 2.9 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 AET37681.1 - 5.8e-08 33.0 0.3 7.5e-06 26.1 0.1 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AET37681.1 - 8.4e-08 31.4 9.3 0.0033 16.3 0.1 4.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AET37681.1 - 3.6e-07 29.4 2.4 3.6e-07 29.4 1.6 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 AET37681.1 - 9e-06 24.4 11.7 0.00018 20.1 0.7 3.9 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.14 AET37681.1 - 4.2e-05 22.7 7.7 0.031 13.3 0.2 3.4 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 AET37681.1 - 0.00015 20.9 1.3 0.00015 20.9 0.9 2.4 1 1 1 2 2 2 1 Thi4 family K_oxygenase PF13434.1 AET37681.1 - 0.00024 20.1 1.3 2.1 7.2 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 AET37681.1 - 0.00032 20.2 1.5 0.081 12.4 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 AET37681.1 - 0.0023 17.5 0.2 0.0023 17.5 0.1 3.0 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AET37681.1 - 0.02 14.2 2.9 0.034 13.5 0.1 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.1 AET37681.1 - 0.043 14.1 0.0 8.2 6.7 0.0 2.8 3 0 0 3 3 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.7 AET37681.1 - 0.081 11.8 3.0 0.66 8.8 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3115 PF11312.3 AET37681.1 - 0.13 11.1 0.2 0.33 9.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3115) Trp_halogenase PF04820.9 AET37681.1 - 0.71 8.4 4.2 1.9 7.0 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GATA PF00320.22 AET37682.1 - 4.9e-17 60.9 2.9 4.9e-17 60.9 2.0 2.4 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 AET37682.1 - 0.11 11.8 0.3 0.33 10.2 0.2 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding Fcf2 PF08698.6 AET37683.1 - 4.2e-32 110.1 0.1 7.9e-32 109.2 0.1 1.4 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing tRNA-synt_2d PF01409.15 AET37685.1 - 8.2e-91 303.5 0.0 1.1e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 AET37685.1 - 8e-07 28.7 0.1 1.8e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 AET37685.1 - 9.2e-07 27.9 1.4 2.6e-05 23.1 0.1 3.0 3 1 0 4 4 4 1 tRNA synthetases class II (D, K and N) PaaX PF07848.7 AET37685.1 - 0.046 13.7 0.0 4.2 7.4 0.0 3.0 3 0 0 3 3 3 0 PaaX-like protein tRNA-synt_His PF13393.1 AET37685.1 - 0.074 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Imm19 PF15567.1 AET37686.1 - 0.097 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 19 Daxx PF03344.10 AET37687.1 - 0.11 10.9 21.8 0.029 12.8 10.5 2.1 2 0 0 2 2 2 0 Daxx Family Nucleoplasmin PF03066.10 AET37687.1 - 2 7.9 18.2 8.1 5.9 12.6 2.1 1 0 0 1 1 1 0 Nucleoplasmin GCR1_C PF12550.3 AET37688.1 - 3.7e-11 42.7 3.1 8.9e-10 38.3 1.0 2.5 2 0 0 2 2 2 2 Transcriptional activator of glycolytic enzymes DUF3835 PF12927.2 AET37689.1 - 2.3e-14 54.1 0.1 2.3e-14 54.1 0.1 5.2 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) Prefoldin PF02996.12 AET37689.1 - 5.1e-09 35.8 1.1 9e-08 31.7 0.0 3.2 4 0 0 4 4 4 1 Prefoldin subunit EPL1 PF10513.4 AET37690.1 - 1.3e-31 110.0 2.9 1.3e-31 110.0 2.0 3.4 3 1 0 3 3 3 1 Enhancer of polycomb-like PGAP1 PF07819.8 AET37691.1 - 3.1e-87 291.8 0.0 4.6e-87 291.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 AET37691.1 - 8.4e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AET37691.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 AET37691.1 - 0.0079 15.5 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 AET37691.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 AET37691.1 - 0.033 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 AET37691.1 - 0.045 13.2 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.15 AET37691.1 - 0.18 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase STE2 PF02116.10 AET37692.1 - 2.5e-99 331.9 25.4 3e-99 331.6 17.6 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR CybS PF05328.7 AET37693.1 - 1.3e-49 167.2 0.0 1.5e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 AET37693.1 - 0.047 13.5 0.3 0.47 10.2 0.2 2.1 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Phage_holin_3 PF05106.7 AET37693.1 - 0.19 11.7 1.3 0.34 10.9 0.9 1.5 1 1 0 1 1 1 0 Phage holin family (Lysis protein S) Acyltransferase PF01553.16 AET37694.1 - 0.00073 18.9 0.3 0.0021 17.4 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase LRR_6 PF13516.1 AET37695.1 - 1.1e-11 43.4 17.2 1 9.6 0.0 8.9 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 AET37695.1 - 2.3e-09 36.6 35.2 0.19 11.3 1.1 7.6 5 2 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AET37695.1 - 2.4e-07 29.8 15.8 3.5 8.0 0.0 8.2 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_8 PF13855.1 AET37695.1 - 2.3e-06 27.2 24.2 0.03 14.0 1.1 5.8 4 1 1 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 AET37695.1 - 8.4e-06 25.1 15.3 8.1 7.1 0.1 8.3 7 1 0 7 7 7 1 Leucine rich repeat MBF1 PF08523.5 AET37696.1 - 8.1e-26 89.8 1.4 1.3e-25 89.1 1.0 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 AET37696.1 - 7.7e-10 38.4 0.1 1.4e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 AET37696.1 - 0.00062 19.7 0.1 0.00092 19.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 AET37696.1 - 0.00062 19.9 0.0 0.0016 18.5 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain TFIID-31kDa PF02291.10 AET37697.1 - 7.3e-53 177.7 0.0 8.1e-53 177.6 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit ChAPs PF09295.5 AET37698.1 - 1.2e-165 551.0 0.0 1.6e-165 550.6 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 AET37698.1 - 0.0022 17.5 1.2 0.65 9.6 0.1 3.9 4 0 0 4 4 4 1 TPR repeat Apc3 PF12895.2 AET37698.1 - 0.031 14.3 0.5 6.8 6.9 0.5 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_32N PF00251.15 AET37699.1 - 7.1e-85 285.0 12.3 1.1e-84 284.4 8.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 AET37699.1 - 3.9e-06 27.1 0.1 8.8e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_76 PF03663.9 AET37700.1 - 4.9e-144 480.2 11.1 6.2e-144 479.9 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 zf-C2H2 PF00096.21 AET37701.1 - 6.6e-05 23.0 2.2 6.6e-05 23.0 1.5 4.1 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET37701.1 - 0.00013 22.0 15.7 0.004 17.3 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET37701.1 - 0.00025 21.1 0.9 0.00025 21.1 0.6 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger TTSSLRR PF12468.3 AET37701.1 - 6 6.4 7.2 0.41 10.2 0.8 2.2 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein RGS PF00615.14 AET37702.1 - 0.017 15.2 0.3 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain DUF4414 PF14377.1 AET37702.1 - 0.065 13.1 1.3 4.8 7.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Leader_CPA1 PF08252.6 AET37703.1 - 3.3e-14 51.7 6.1 3.4e-14 51.6 4.3 1.0 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide CPSase_sm_chain PF00988.17 AET37704.1 - 3.3e-42 143.0 0.0 5e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 AET37704.1 - 4e-41 140.5 0.0 6.3e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AET37704.1 - 5.6e-06 25.9 0.1 0.00046 19.7 0.1 2.9 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 AET37704.1 - 0.072 12.5 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family RCC1 PF00415.13 AET37705.1 - 1.8e-13 50.4 2.0 0.00011 22.3 0.1 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 AET37705.1 - 8.6e-08 32.1 0.5 5e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 BTB/POZ domain RCC1_2 PF13540.1 AET37705.1 - 1.1e-07 31.2 11.5 1.4e-06 27.7 0.2 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat SNF2_N PF00176.18 AET37706.1 - 2.1e-80 269.7 0.4 3.4e-80 269.0 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 AET37706.1 - 1e-42 144.5 2.8 1e-42 144.5 1.9 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 AET37706.1 - 1.1e-34 119.1 2.7 1.1e-34 119.1 1.9 2.8 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 AET37706.1 - 4.9e-16 58.3 0.0 1.1e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET37706.1 - 2.4e-10 40.5 0.1 3.2e-09 36.8 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AET37706.1 - 1.7e-05 24.4 0.0 4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 AET37706.1 - 0.0033 17.4 0.0 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 AET37706.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 AET37706.1 - 0.03 14.2 2.3 0.078 12.8 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 AET37706.1 - 0.26 11.4 2.1 0.87 9.7 0.1 3.0 3 1 0 3 3 3 0 AAA domain Ribonuclease_3 PF00636.21 AET37707.1 - 3.5e-17 62.9 0.0 1.1e-16 61.2 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AET37707.1 - 5.1e-13 49.1 0.0 1.1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 AET37707.1 - 0.00016 22.1 0.8 0.00047 20.6 0.0 2.2 3 0 0 3 3 3 1 Double-stranded RNA binding motif DUF382 PF04037.8 AET37708.1 - 3.2e-50 169.2 0.0 8.2e-50 167.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 AET37708.1 - 1.5e-18 65.8 1.3 2.6e-18 65.1 0.9 1.4 1 0 0 1 1 1 1 PSP TPR_MLP1_2 PF07926.7 AET37709.1 - 0.022 14.5 1.9 0.025 14.3 1.3 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FokI_N PF02981.10 AET37709.1 - 0.051 13.2 0.2 0.055 13.0 0.1 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain Ribosomal_S7e PF01251.13 AET37709.1 - 0.078 12.4 0.4 0.09 12.2 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S7e Med11 PF10280.4 AET37709.1 - 0.11 12.5 1.3 0.14 12.1 0.9 1.3 1 1 0 1 1 1 0 Mediator complex protein Nsp1_C PF05064.8 AET37709.1 - 0.23 11.1 3.0 0.32 10.6 2.0 1.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF3763 PF12592.3 AET37709.1 - 1.4 8.6 5.4 9.2 5.9 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3763) DUF2034 PF10356.4 AET37710.1 - 4.7e-58 195.4 0.1 5.4e-58 195.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 AET37710.1 - 2e-05 24.3 0.1 0.008 15.9 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease Mito_carr PF00153.22 AET37711.1 - 1.6e-29 101.4 6.1 7.6e-13 47.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SART-1 PF03343.8 AET37712.1 - 1.5e-70 238.3 32.3 5.6e-69 233.0 22.4 2.0 1 1 0 1 1 1 1 SART-1 family DEAD PF00270.24 AET37712.1 - 0.023 14.1 0.1 0.071 12.6 0.1 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF3596 PF12167.3 AET37712.1 - 0.48 9.9 2.9 2.1 7.9 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) Nop PF01798.13 AET37713.1 - 7.7e-60 200.5 0.9 2.9e-59 198.6 0.7 2.0 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AET37713.1 - 3.4e-26 90.7 0.0 6e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AET37713.1 - 6.3e-19 67.9 3.0 6.3e-19 67.9 2.1 3.0 2 1 1 3 3 3 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 AET37713.1 - 0.36 10.7 22.5 0.72 9.7 15.6 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 AET37713.1 - 1.1 9.1 30.3 2.7 7.8 21.0 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ebola_NP PF05505.7 AET37713.1 - 7.1 4.5 18.5 9.2 4.1 12.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein CTP_transf_1 PF01148.15 AET37714.1 - 2.5e-21 76.5 9.4 2.3e-17 63.5 5.6 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Ribosomal_L18ae PF01775.12 AET37715.1 - 2.6e-57 192.0 0.8 3.3e-57 191.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DDE_Tnp_1_3 PF13612.1 AET37715.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 Transposase DDE domain NTP_transf_3 PF12804.2 AET37716.1 - 0.098 12.7 0.1 0.38 10.8 0.0 2.0 3 0 0 3 3 3 0 MobA-like NTP transferase domain Cation_efflux PF01545.16 AET37718.1 - 3.9e-82 275.5 7.8 4.6e-82 275.2 5.4 1.0 1 0 0 1 1 1 1 Cation efflux family SUN PF03856.8 AET37719.1 - 3.7e-83 278.6 19.4 4.5e-83 278.3 13.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Bac_rhodopsin PF01036.13 AET37720.1 - 1.7e-39 135.4 17.1 2e-39 135.1 11.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein TPPK_C PF12555.3 AET37720.1 - 3.5 7.4 7.5 15 5.4 0.0 4.0 4 0 0 4 4 4 0 Thiamine pyrophosphokinase C terminal COX6B PF02297.12 AET37721.1 - 1.3e-22 79.6 3.1 1.6e-22 79.2 2.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb RabGAP-TBC PF00566.13 AET37722.1 - 8.2e-20 71.2 7.3 4e-19 68.9 3.1 2.4 2 1 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.27 AET37723.1 - 3.3e-12 45.7 3.1 0.098 12.5 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat CDC45 PF02724.9 AET37723.1 - 0.39 8.6 29.6 0.071 11.1 15.8 2.2 2 0 0 2 2 2 0 CDC45-like protein CENP-T PF15511.1 AET37723.1 - 4.2 6.4 34.8 7.7 5.6 20.0 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T ABC_tran PF00005.22 AET37724.1 - 4e-18 66.0 0.0 1.2e-17 64.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AET37724.1 - 1.3e-12 48.2 1.4 2.8e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AET37724.1 - 6.7e-07 28.7 0.0 0.02 13.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 AET37724.1 - 1.6e-05 24.2 0.3 0.067 12.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AET37724.1 - 5.1e-05 23.6 0.2 6.1e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AET37724.1 - 0.00049 19.3 0.0 0.00075 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AET37724.1 - 0.00093 18.6 0.2 0.0018 17.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 AET37724.1 - 0.0019 17.7 0.1 0.055 12.8 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 AET37724.1 - 0.0079 16.3 0.7 0.088 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AET37724.1 - 0.02 15.6 0.5 0.037 14.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AET37724.1 - 0.036 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 AET37724.1 - 0.042 13.7 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.1 AET37724.1 - 0.05 12.0 0.1 0.073 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 AET37724.1 - 0.057 13.2 0.1 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Dynamin family DUF3584 PF12128.3 AET37724.1 - 0.068 10.4 0.1 0.09 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_24 PF13479.1 AET37724.1 - 0.07 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain FA_hydroxylase PF04116.8 AET37725.1 - 2.3e-10 40.8 20.5 2.3e-10 40.8 14.2 2.9 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Pkinase PF00069.20 AET37726.1 - 7e-37 126.9 0.4 3.8e-36 124.5 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37726.1 - 4e-23 81.7 0.0 5.9e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AET37726.1 - 7e-06 25.2 0.1 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET37726.1 - 1.6e-05 24.7 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AET37726.1 - 0.0066 16.0 0.1 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 AET37726.1 - 0.0087 15.4 0.2 0.02 14.2 0.2 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 AET37726.1 - 0.053 12.4 0.1 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.4 AET37726.1 - 0.09 12.0 0.1 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_47 PF01532.15 AET37727.1 - 2.8e-83 280.1 1.5 3.4e-83 279.8 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Myb_DNA-bind_4 PF13837.1 AET37728.1 - 6e-06 26.2 0.4 1.1e-05 25.4 0.1 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 AET37728.1 - 0.079 12.8 1.4 0.25 11.2 0.2 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain CysG_dimeriser PF10414.4 AET37728.1 - 0.14 11.6 0.5 16 5.0 0.2 2.7 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region SHMT PF00464.14 AET37729.1 - 4e-205 680.7 0.0 4.6e-205 680.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 AET37729.1 - 3.1e-06 26.3 0.0 7.6e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AET37729.1 - 0.00012 21.3 0.0 0.0002 20.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AET37729.1 - 0.00035 19.4 0.0 0.00057 18.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V FR47 PF08445.5 AET37729.1 - 0.096 12.4 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Baculo_DNA_bind PF04786.7 AET37729.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 ssDNA binding protein DUF4559 PF15112.1 AET37729.1 - 0.2 10.8 0.1 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) bZIP_2 PF07716.10 AET37730.1 - 0.00013 21.7 7.4 0.00013 21.7 5.2 1.6 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 AET37730.1 - 0.00022 21.1 5.6 0.00041 20.2 3.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor RNase_T PF00929.19 AET37731.1 - 5.2e-31 108.1 0.1 7.6e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.20 AET37732.1 - 4.6e-57 193.1 0.2 3e-36 124.9 0.5 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AET37732.1 - 1.8e-24 86.2 0.1 5.9e-20 71.4 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AET37732.1 - 4.1e-06 25.9 0.0 1.2e-05 24.3 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Response_reg PF00072.19 AET37732.1 - 0.00034 20.6 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain Kdo PF06293.9 AET37732.1 - 0.00064 18.8 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 AET37732.1 - 0.0082 16.5 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 AET37732.1 - 0.013 15.3 0.5 0.048 13.4 0.0 2.2 2 0 0 2 2 2 0 PAS fold APH PF01636.18 AET37732.1 - 0.015 15.0 0.0 0.17 11.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family B3_4 PF03483.12 AET37733.1 - 2e-29 102.2 0.0 3.1e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 AET37733.1 - 2.6e-19 68.8 0.0 3.6e-16 58.7 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 AET37733.1 - 0.01 14.9 0.1 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein SLS PF14611.1 AET37733.1 - 0.048 13.0 0.1 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Ribosomal_L22e PF01776.12 AET37734.1 - 6e-43 145.3 0.5 7.4e-43 145.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF3115 PF11312.3 AET37735.1 - 6e-100 334.1 0.0 7e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Methyltransf_31 PF13847.1 AET37735.1 - 0.036 13.6 0.1 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain NMT1 PF09084.6 AET37735.1 - 0.037 13.6 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 NMT1/THI5 like Mob1_phocein PF03637.12 AET37736.1 - 1.3e-72 243.1 1.3 1.6e-72 242.8 0.9 1.1 1 0 0 1 1 1 1 Mob1/phocein family RNA_pol PF00940.14 AET37737.1 - 7e-164 545.1 0.3 1.2e-163 544.3 0.0 1.5 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 AET37737.1 - 6.5e-87 291.7 0.5 1.3e-86 290.8 0.3 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal YxiJ PF14176.1 AET37737.1 - 0.42 10.7 4.6 1.9 8.6 0.0 3.6 3 0 0 3 3 3 0 YxiJ-like protein Tubulin PF00091.20 AET37738.1 - 6.4e-70 235.3 0.0 1.1e-69 234.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AET37738.1 - 3.4e-49 166.0 0.1 6.4e-49 165.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 AET37738.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 AET37738.1 - 0.013 15.5 0.0 0.039 13.9 0.0 1.8 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain YbaJ PF10757.4 AET37739.1 - 4.6 7.3 5.6 0.93 9.6 0.5 2.3 3 1 1 4 4 4 0 Biofilm formation regulator YbaJ Ras PF00071.17 AET37740.1 - 2e-63 212.5 0.5 2.4e-63 212.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET37740.1 - 1.9e-21 76.7 0.1 3.1e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET37740.1 - 3e-18 65.6 0.2 3.8e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET37740.1 - 3.8e-07 29.4 0.1 5.3e-07 29.0 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AET37740.1 - 2.1e-05 24.0 0.2 4.8e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AET37740.1 - 3.8e-05 23.6 0.1 5.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AET37740.1 - 0.00042 19.5 0.1 0.00067 18.9 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 AET37740.1 - 0.002 18.2 0.0 0.0035 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AET37740.1 - 0.0069 16.5 0.0 0.14 12.3 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 AET37740.1 - 0.014 14.6 0.2 0.089 12.0 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 AET37740.1 - 0.017 14.2 0.0 0.033 13.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 AET37740.1 - 0.022 14.7 0.1 0.087 12.8 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 AET37740.1 - 0.025 13.5 0.2 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 AET37740.1 - 0.034 13.6 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 AET37740.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 AET37740.1 - 0.074 13.3 0.1 0.12 12.6 0.1 1.6 1 1 0 1 1 1 0 ABC transporter CENP-M PF11111.3 AET37740.1 - 0.077 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) PduV-EutP PF10662.4 AET37740.1 - 0.09 12.2 0.1 1.8 8.0 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF788 PF05620.6 AET37741.1 - 2.2e-33 115.5 0.1 2.3e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Actin PF00022.14 AET37742.1 - 1.9e-160 533.6 0.0 2.1e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 AET37742.1 - 0.085 13.2 0.1 0.38 11.1 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Sugar_tr PF00083.19 AET37743.1 - 8.2e-71 238.9 33.2 1e-70 238.5 23.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET37743.1 - 8.5e-18 64.1 34.0 2.2e-16 59.5 13.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily SPC22 PF04573.7 AET37744.1 - 3.4e-55 185.9 0.5 3.9e-55 185.7 0.4 1.0 1 0 0 1 1 1 1 Signal peptidase subunit rRNA_processing PF08524.6 AET37745.1 - 9.3e-35 119.5 23.5 1.1e-34 119.4 16.3 1.0 1 0 0 1 1 1 1 rRNA processing Peptidase_U35_2 PF14550.1 AET37745.1 - 0.049 13.2 0.0 0.066 12.8 0.0 1.3 1 1 0 1 1 1 0 Putative phage protease XkdF DUF501 PF04417.7 AET37745.1 - 1 9.1 6.1 1.6 8.6 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF501) GTP_EFTU PF00009.22 AET37746.1 - 6.3e-60 201.8 0.4 1.4e-59 200.7 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AET37746.1 - 2.1e-32 111.2 0.0 4.7e-32 110.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 AET37746.1 - 4.6e-32 109.6 0.0 1.1e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AET37746.1 - 1.8e-24 85.4 0.0 4.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AET37746.1 - 1.2e-13 50.9 0.3 4.3e-13 49.1 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 AET37746.1 - 0.018 15.5 0.0 0.048 14.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Cu-oxidase_3 PF07732.10 AET37747.1 - 1e-40 138.1 6.7 1.6e-36 124.5 1.5 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AET37747.1 - 4.4e-40 136.3 12.6 3.4e-37 127.0 1.0 3.1 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 AET37747.1 - 2.1e-34 118.7 6.7 3.2e-30 105.1 0.1 3.4 3 0 0 3 3 3 2 Multicopper oxidase Antitoxin-MazE PF04014.13 AET37747.1 - 0.0082 15.8 0.0 6.3 6.6 0.0 3.3 3 0 0 3 3 3 2 Antidote-toxin recognition MazE Cupredoxin_1 PF13473.1 AET37747.1 - 0.012 15.4 0.0 2.1 8.2 0.0 3.7 4 1 0 4 4 4 0 Cupredoxin-like domain Med14 PF08638.6 AET37748.1 - 3.1e-63 212.5 0.6 1e-62 210.8 0.4 2.0 1 0 0 1 1 1 1 Mediator complex subunit MED14 USP8_dimer PF08969.6 AET37749.1 - 7.9e-07 29.0 0.8 1.3e-06 28.3 0.2 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain CutA1 PF03091.10 AET37749.1 - 0.096 12.3 0.2 15 5.3 0.0 2.6 2 1 0 2 2 2 0 CutA1 divalent ion tolerance protein OTU PF02338.14 AET37750.1 - 2.5e-11 44.2 0.0 4.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_jaz PF12171.3 AET37751.1 - 4.3e-10 39.4 6.2 1.8e-09 37.4 3.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AET37751.1 - 0.00015 21.8 0.1 0.00026 21.0 0.1 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-AD PF07776.10 AET37751.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-U1 PF06220.7 AET37751.1 - 0.041 13.4 1.4 0.069 12.7 1.0 1.3 1 0 0 1 1 1 0 U1 zinc finger zf-met PF12874.2 AET37751.1 - 0.067 13.4 2.3 0.067 13.4 1.6 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 AET37751.1 - 0.086 13.2 2.0 0.11 12.9 0.5 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AET37751.1 - 3.3 8.1 5.4 1.4 9.3 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double domain Ribosomal_L16 PF00252.13 AET37752.1 - 1.1e-34 119.0 0.1 1.4e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTBV_P46 PF06216.6 AET37752.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein PMM PF03332.8 AET37753.1 - 4.1e-111 369.8 0.4 4.6e-111 369.6 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 AET37753.1 - 4.3e-07 29.7 0.0 2.8e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 AET37753.1 - 0.02 13.9 0.1 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Chordopox_A13L PF05961.6 AET37753.1 - 0.024 14.5 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF1640 PF07798.6 AET37754.1 - 3.7e-62 209.4 8.2 4.4e-62 209.2 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3523 PF12037.3 AET37754.1 - 0.037 12.9 7.7 0.054 12.4 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) PLRV_ORF5 PF01690.12 AET37754.1 - 0.13 11.4 0.3 0.25 10.4 0.0 1.5 1 1 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1732 PF08340.6 AET37754.1 - 0.14 11.9 7.7 0.26 11.1 5.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) FlaC_arch PF05377.6 AET37754.1 - 0.19 11.6 2.5 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TBPIP PF07106.8 AET37754.1 - 1.4 8.4 9.0 2.7 7.5 6.2 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1359 PF07097.6 AET37754.1 - 1.8 8.6 6.6 1.1 9.2 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1359) Baculo_PEP_C PF04513.7 AET37754.1 - 2.6 7.8 5.6 2.9 7.7 1.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 AET37754.1 - 2.8 7.7 6.0 9.5 6.0 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_lysis PF03245.8 AET37754.1 - 5.2 7.0 10.2 0.65 10.0 0.6 2.3 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein YlqD PF11068.3 AET37754.1 - 6.1 6.8 10.6 0.79 9.7 3.2 2.1 1 1 2 3 3 3 0 YlqD protein RCC1 PF00415.13 AET37755.1 - 1.2e-26 92.6 2.8 9.3e-06 25.7 0.0 5.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AET37755.1 - 1.7e-15 56.1 7.7 3.7e-09 35.9 0.1 4.5 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat V-SNARE_C PF12352.3 AET37756.1 - 6e-07 29.4 4.1 6e-07 29.4 2.8 3.2 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 AET37756.1 - 0.0034 17.0 0.8 0.0034 17.0 0.5 2.6 2 1 0 2 2 2 1 Sec20 BBP1_C PF15272.1 AET37756.1 - 0.0035 16.9 3.6 0.0035 16.9 2.5 2.0 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal DUF489 PF04356.7 AET37756.1 - 0.0043 16.6 1.1 0.27 10.7 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF489) Apc4 PF12896.2 AET37756.1 - 0.0049 16.1 1.4 0.057 12.7 0.1 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 Med30 PF11315.3 AET37756.1 - 0.014 15.4 2.8 0.16 12.0 0.2 2.4 2 0 0 2 2 2 0 Mediator complex subunit 30 V_ATPase_I PF01496.14 AET37756.1 - 0.015 13.2 6.7 0.023 12.5 4.5 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec5 PF15469.1 AET37756.1 - 0.2 11.3 6.0 1.2 8.7 0.1 2.4 2 1 0 2 2 2 0 Exocyst complex component Sec5 EMP24_GP25L PF01105.19 AET37756.1 - 0.25 11.0 4.0 1.7 8.2 0.4 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Use1 PF09753.4 AET37756.1 - 0.29 10.5 8.8 6.9 6.0 6.1 2.1 1 1 0 1 1 1 0 Membrane fusion protein Use1 CENP-H PF05837.7 AET37756.1 - 0.52 10.5 5.1 0.9 9.7 0.4 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.6 AET37756.1 - 0.53 8.8 8.4 0.093 11.3 1.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 AET37756.1 - 3.9 7.0 14.1 9.8 5.7 0.4 2.6 2 1 0 2 2 2 0 IncA protein Snapin_Pallidin PF14712.1 AET37756.1 - 6 7.2 12.2 1.3 9.3 1.4 2.7 3 0 0 3 3 3 0 Snapin/Pallidin IFP_35_N PF07334.8 AET37756.1 - 7.3 6.6 7.3 0.77 9.7 0.3 2.8 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus RNA_bind PF08675.6 AET37757.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain FCH PF00611.18 AET37758.1 - 2.3e-17 62.9 2.7 2.9e-17 62.6 0.0 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 AET37758.1 - 2.4e-12 46.3 0.0 5.5e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 AET37758.1 - 1.5e-09 37.6 1.3 3.1e-09 36.6 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain TFIIA_gamma_N PF02268.11 AET37758.1 - 0.082 12.5 0.0 6.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Transcription initiation factor IIA, gamma subunit, helical domain Rdx PF10262.4 AET37759.1 - 4e-27 94.0 0.0 5.2e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family Lectin_leg-like PF03388.8 AET37760.1 - 1.8e-39 135.2 0.1 2.6e-39 134.7 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family CRC_subunit PF08624.5 AET37761.1 - 6.1e-41 139.5 0.1 9.6e-41 138.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit GFO_IDH_MocA PF01408.17 AET37762.1 - 7.2e-20 71.7 0.1 1.4e-19 70.7 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AET37762.1 - 4.5e-09 36.1 0.0 7.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DCP1 PF06058.8 AET37763.1 - 4.5e-18 65.4 1.3 1.9e-09 37.5 0.0 3.0 2 1 1 3 3 3 3 Dcp1-like decapping family Spt20 PF12090.3 AET37764.1 - 5.2e-53 179.0 13.0 5.2e-53 179.0 9.0 3.8 3 1 0 3 3 3 1 Spt20 family PEX11 PF05648.9 AET37765.1 - 5.3e-61 205.7 0.6 6.1e-61 205.5 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sld5 PF05916.6 AET37766.1 - 5.8e-11 42.6 0.0 7.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein TPR_11 PF13414.1 AET37767.1 - 9e-30 102.1 20.6 3.9e-07 29.6 0.0 10.0 7 4 4 11 11 11 7 TPR repeat TPR_12 PF13424.1 AET37767.1 - 5e-27 93.6 17.6 4.5e-07 29.7 0.1 10.5 8 2 1 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 AET37767.1 - 2.2e-25 86.4 29.1 0.0028 17.4 0.1 14.8 15 1 1 16 16 16 7 Tetratricopeptide repeat TPR_1 PF00515.23 AET37767.1 - 4.5e-22 76.6 27.5 0.00051 19.5 0.0 13.3 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_16 PF13432.1 AET37767.1 - 4.7e-20 71.7 7.4 0.0003 21.3 0.3 8.6 8 3 4 12 12 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 AET37767.1 - 3.8e-18 65.5 19.5 0.00027 21.2 0.1 10.4 8 3 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 AET37767.1 - 7.9e-18 63.3 9.8 0.38 11.5 0.0 13.3 11 3 4 15 15 14 3 Tetratricopeptide repeat Apc3 PF12895.2 AET37767.1 - 3.3e-13 49.5 18.9 0.00021 21.3 0.1 7.7 5 3 3 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AET37767.1 - 2.9e-12 45.4 40.4 0.051 13.3 0.0 14.9 19 1 0 19 19 19 5 Tetratricopeptide repeat TPR_6 PF13174.1 AET37767.1 - 4.6e-10 39.2 27.6 0.11 13.0 0.0 13.5 14 1 0 14 14 14 2 Tetratricopeptide repeat TPR_17 PF13431.1 AET37767.1 - 1e-05 25.3 7.8 3.9 7.8 0.0 10.3 12 1 0 12 12 12 1 Tetratricopeptide repeat TPR_9 PF13371.1 AET37767.1 - 0.00039 20.2 0.7 0.47 10.3 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 AET37767.1 - 0.12 12.3 20.0 2.7 8.0 0.0 7.2 8 1 1 9 9 9 0 Tetratricopeptide repeat RRM_5 PF13893.1 AET37768.1 - 3.3e-07 30.0 0.1 6.6e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET37768.1 - 0.00031 20.3 0.0 0.00065 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMRL_synthase PF00885.14 AET37769.1 - 3.1e-44 150.1 0.1 3.9e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Hist_deacetyl PF00850.14 AET37770.1 - 1.1e-80 271.3 0.0 1.6e-80 270.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DnaJ PF00226.26 AET37771.1 - 3.9e-06 26.5 0.1 6.5e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain RE_CfrBI PF09516.5 AET37771.1 - 0.033 13.0 0.1 0.04 12.8 0.1 1.1 1 0 0 1 1 1 0 CfrBI restriction endonuclease Pam16 PF03656.8 AET37771.1 - 0.062 13.1 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 Pam16 zf-DHHC PF01529.15 AET37773.1 - 3.9e-35 120.7 14.2 3.9e-35 120.7 9.8 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase OMP_b-brl_2 PF13568.1 AET37773.1 - 0.031 14.0 1.0 0.044 13.5 0.7 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Syja_N PF02383.13 AET37775.1 - 1.2e-91 306.8 0.2 1.2e-91 306.8 0.1 2.7 2 1 1 4 4 4 1 SacI homology domain DUF3533 PF12051.3 AET37776.1 - 2.7e-106 355.5 9.1 3.1e-106 355.3 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) CDC50 PF03381.10 AET37777.1 - 4.4e-90 301.6 0.8 5.8e-90 301.2 0.0 1.6 2 1 1 3 3 3 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Aminotran_3 PF00202.16 AET37778.1 - 1.3e-100 336.5 0.0 1.5e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Na_Ca_ex PF01699.19 AET37780.1 - 5.9e-27 93.9 35.8 1.3e-18 66.9 7.4 4.0 5 1 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 AET37780.1 - 4.7e-12 46.1 3.0 4.7e-12 46.1 2.0 4.2 5 1 0 5 5 5 1 Domain of unknown function (DUF307) Trs65 PF12735.2 AET37780.1 - 0.044 13.0 0.4 0.092 12.0 0.3 1.4 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Shisa PF13908.1 AET37780.1 - 0.062 13.4 1.0 0.2 11.8 0.7 1.9 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4094 PF13334.1 AET37780.1 - 0.082 13.2 0.4 0.84 10.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) IF4E PF01652.13 AET37781.1 - 2.4e-57 193.0 0.1 3.6e-57 192.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Abhydrolase_5 PF12695.2 AET37782.1 - 1.9e-17 63.3 0.0 2.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AET37782.1 - 8.1e-14 52.0 0.0 2.5e-12 47.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET37782.1 - 1.4e-07 31.3 0.4 0.00018 21.1 0.2 2.8 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AET37782.1 - 6e-06 25.6 0.0 2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 AET37782.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 AET37782.1 - 0.049 13.3 0.0 0.73 9.5 0.0 2.4 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 AET37782.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF818 PF05677.7 AET37782.1 - 0.11 11.2 0.3 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) WD40 PF00400.27 AET37783.1 - 2.1e-16 59.1 10.5 4.3e-07 29.5 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat zf-rbx1 PF12678.2 AET37783.1 - 0.0038 17.2 5.8 0.0099 15.9 4.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AET37783.1 - 0.92 9.3 14.5 0.045 13.5 5.8 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 AET37783.1 - 1.4 8.6 8.6 0.4 10.3 2.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.11 AET37784.1 - 1.9e-20 72.8 40.1 3.4e-12 45.7 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AET37784.1 - 0.035 12.6 38.4 0.69 8.4 26.7 2.2 1 1 0 1 1 1 0 Sugar (and other) transporter WD40 PF00400.27 AET37785.1 - 8.4e-39 130.1 11.7 2.7e-09 36.5 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 AET37785.1 - 2.3e-06 27.4 3.1 0.00035 20.3 0.8 3.5 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 AET37785.1 - 0.0062 15.3 2.4 4.8 5.8 0.1 3.6 1 1 1 3 3 3 2 Nup133 N terminal like 6PF2K PF01591.13 AET37786.1 - 6.9e-48 162.6 0.2 1.1e-47 162.0 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_17 PF13207.1 AET37786.1 - 0.00043 21.0 0.0 0.001 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AET37786.1 - 0.0006 19.6 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 AET37786.1 - 0.0084 15.3 0.0 0.018 14.2 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 AET37786.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.18 AET37786.1 - 0.065 12.6 0.1 0.55 9.5 0.1 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 AET37786.1 - 0.11 12.7 0.3 0.24 11.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AET37786.1 - 0.13 11.5 0.1 0.5 9.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain Med7 PF05983.6 AET37787.1 - 1.6e-65 219.8 0.4 1.8e-65 219.6 0.3 1.0 1 0 0 1 1 1 1 MED7 protein zf-rbx1 PF12678.2 AET37788.1 - 1.6e-31 108.2 13.9 2e-31 107.8 9.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AET37788.1 - 7.4e-17 60.9 10.7 9.5e-17 60.6 7.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 AET37788.1 - 4e-07 29.7 12.4 3.3e-06 26.8 8.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AET37788.1 - 0.0014 18.2 12.0 0.0067 16.0 8.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET37788.1 - 0.0082 16.1 2.2 0.0082 16.1 1.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 AET37788.1 - 0.077 12.5 3.0 0.16 11.5 2.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 AET37788.1 - 0.16 11.6 10.7 10 5.8 7.5 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 AET37788.1 - 0.39 10.8 9.8 30 4.8 6.8 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 AET37788.1 - 0.47 10.4 9.6 1.3 9.0 6.6 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 AET37788.1 - 1.5 8.8 10.2 6.7 6.7 7.2 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 AET37788.1 - 1.8 8.5 7.4 1.3 9.0 0.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AET37788.1 - 2.3 7.9 11.8 15 5.3 8.2 2.2 1 1 0 1 1 1 0 zinc-RING finger domain PDT PF00800.13 AET37789.1 - 9.7e-50 168.6 0.0 1.2e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 AET37789.1 - 0.0025 17.2 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain ATP11 PF06644.6 AET37790.1 - 1.1e-95 320.1 3.8 1.3e-95 319.9 2.6 1.0 1 0 0 1 1 1 1 ATP11 protein Capsule_synth PF05159.9 AET37790.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein TPR_11 PF13414.1 AET37791.1 - 1.1e-14 53.8 4.5 7.6e-09 35.1 0.1 5.1 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.1 AET37791.1 - 9.3e-10 38.2 0.1 0.054 14.1 0.1 5.8 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 AET37791.1 - 6.1e-08 32.4 0.1 0.0086 15.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 AET37791.1 - 8.5e-08 32.6 0.3 0.5 11.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 AET37791.1 - 6.9e-07 28.7 5.2 0.0032 17.2 0.0 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 AET37791.1 - 4.3e-06 26.1 1.1 0.57 10.0 0.0 5.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 AET37791.1 - 2.7e-05 24.3 0.6 0.33 11.3 0.2 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 AET37791.1 - 5.4e-05 22.6 2.8 0.11 12.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 AET37791.1 - 0.00014 21.3 2.3 0.19 11.5 0.0 4.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 AET37791.1 - 0.00026 20.9 4.6 0.081 13.1 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 AET37791.1 - 0.0032 17.2 0.8 3.6 7.5 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat RPA_C PF08784.6 AET37792.1 - 1.8e-09 37.9 0.2 8.4e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 AET37792.1 - 2.9e-07 30.2 0.4 4.9e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Glyco_hydro_72 PF03198.9 AET37793.1 - 2.1e-131 437.6 0.8 2.8e-131 437.2 0.5 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 AET37793.1 - 0.004 16.3 0.1 0.039 13.1 0.1 2.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.3 AET37793.1 - 0.052 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core F-box-like PF12937.2 AET37794.1 - 2.8e-06 26.9 2.1 2.8e-06 26.9 1.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AET37794.1 - 1.5e-05 24.5 6.4 4e-05 23.1 2.7 2.6 2 0 0 2 2 2 1 F-box domain zf-DNL PF05180.7 AET37795.1 - 9.6e-32 108.5 1.7 1.5e-31 107.8 1.2 1.3 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 AET37795.1 - 0.034 13.8 0.5 0.059 13.0 0.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PHD PF00628.24 AET37795.1 - 0.056 13.1 2.0 1.3 8.8 0.4 2.6 2 1 0 2 2 2 0 PHD-finger zinc_ribbon_5 PF13719.1 AET37795.1 - 0.13 11.8 1.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-CSL PF05207.8 AET37795.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_4 PF13717.1 AET37795.1 - 1.9 8.2 5.3 13 5.5 0.1 2.5 1 1 1 2 2 2 0 zinc-ribbon domain CorA PF01544.13 AET37797.1 - 1.1e-43 149.3 0.2 1.9e-25 89.4 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein UPF0220 PF05255.6 AET37798.1 - 3.1e-62 208.6 1.6 3.5e-62 208.5 1.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.20 AET37799.1 - 1e-57 195.2 0.0 1.2e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37799.1 - 1.4e-29 102.9 0.0 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET37799.1 - 1.1e-06 27.8 0.0 1.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AET37799.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AET37799.1 - 0.0075 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 AET37799.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S11 PF00411.14 AET37800.1 - 2e-06 27.9 0.0 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L23 PF00276.15 AET37801.1 - 6.6e-21 74.0 2.3 6.6e-21 74.0 1.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 AET37801.1 - 1.6e-19 69.6 9.3 1.6e-19 69.6 6.5 2.3 3 1 0 3 3 3 1 Ribosomal protein L23, N-terminal domain Lipoprotein_1 PF00820.14 AET37801.1 - 0.01 14.9 0.3 0.015 14.3 0.2 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein DUF3667 PF12412.3 AET37802.1 - 9 5.6 7.0 5.9 6.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) Ldh_1_N PF00056.18 AET37803.1 - 4.6e-39 133.4 0.5 7.7e-39 132.7 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AET37803.1 - 6.3e-31 107.4 0.0 1.4e-30 106.2 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain TRM13 PF05206.9 AET37804.1 - 8.5e-77 257.8 0.0 1.2e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 AET37804.1 - 2.7e-11 42.6 2.7 2.7e-11 42.6 1.8 2.5 3 0 0 3 3 3 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 AET37804.1 - 1.1e-09 37.8 1.3 1.1e-09 37.8 0.9 2.4 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 AET37804.1 - 0.0011 18.7 0.2 0.0035 17.0 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ras PF00071.17 AET37805.1 - 2.3e-31 108.3 0.1 6e-27 94.0 0.0 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 AET37805.1 - 2e-10 41.1 0.2 2.1e-06 28.2 0.0 3.0 2 1 0 3 3 3 2 Miro-like protein Arf PF00025.16 AET37805.1 - 5.5e-08 32.2 0.3 3.1e-07 29.8 0.1 2.1 3 0 0 3 3 3 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET37805.1 - 0.0003 19.9 0.5 0.0095 15.0 0.1 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AET37805.1 - 0.0016 17.8 0.0 0.0044 16.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF1947 PF09183.5 AET37805.1 - 0.064 13.0 4.3 0.53 10.0 0.1 3.6 3 2 1 4 4 4 0 Domain of unknown function (DUF1947) AAA_5 PF07728.9 AET37805.1 - 0.078 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 AET37805.1 - 0.12 11.9 0.8 0.28 10.7 0.6 1.7 1 1 0 1 1 1 0 AAA domain UPF0020 PF01170.13 AET37806.1 - 5.4e-14 52.1 0.0 1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 AET37806.1 - 5.2e-09 36.1 0.0 9.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 AET37806.1 - 0.0099 15.3 0.6 4.5 6.6 0.0 2.8 2 1 1 3 3 3 2 D12 class N6 adenine-specific DNA methyltransferase N6_Mtase PF02384.11 AET37806.1 - 0.03 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Cons_hypoth95 PF03602.10 AET37806.1 - 0.048 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RRM_1 PF00076.17 AET37807.1 - 4.1e-37 125.6 0.2 5e-19 67.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET37807.1 - 2.1e-33 114.1 0.0 2.5e-16 59.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET37807.1 - 1.6e-12 47.0 0.0 1.4e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF948 PF06103.6 AET37807.1 - 1.9 8.4 7.5 1.4 8.8 1.8 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Nramp PF01566.13 AET37808.1 - 2e-85 286.7 16.9 3.8e-85 285.8 11.7 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein PBP1_TM PF14812.1 AET37808.1 - 0.029 14.6 0.1 0.029 14.6 0.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S19e PF01090.14 AET37809.1 - 1.6e-55 186.3 0.0 1.8e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18e PF00828.14 AET37810.1 - 5.2e-23 81.8 0.1 9.8e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 MFS_1 PF07690.11 AET37811.1 - 1.8e-31 109.1 36.6 1.8e-31 109.1 25.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 AET37811.1 - 0.0001 20.8 38.4 0.0001 20.8 26.6 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 AET37811.1 - 0.00042 19.0 44.6 0.0026 16.3 10.4 3.4 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 AET37811.1 - 0.00081 19.1 0.6 0.00081 19.1 0.4 3.0 3 1 1 4 4 4 1 MFS_1 like family NS3_envE PF02723.9 AET37811.1 - 0.029 14.2 5.3 0.054 13.4 0.4 2.8 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Redoxin PF08534.5 AET37812.1 - 9.4e-28 96.5 0.0 1.1e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 AET37812.1 - 3.3e-10 39.7 0.0 3.9e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family PCI PF01399.22 AET37813.1 - 0.0053 17.0 5.5 0.17 12.2 0.1 3.5 2 2 1 3 3 3 1 PCI domain YvbH_ext PF11724.3 AET37813.1 - 0.017 14.7 0.0 0.048 13.3 0.0 1.7 1 0 0 1 1 1 0 YvbH-like oligomerisation region DUF285 PF03382.9 AET37813.1 - 0.02 14.4 1.7 0.049 13.2 0.6 2.0 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 TPR_2 PF07719.12 AET37813.1 - 0.02 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 AET37813.1 - 0.073 12.9 0.0 0.28 11.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 AET37813.1 - 0.11 12.9 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 AET37813.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat GCR1_C PF12550.3 AET37815.1 - 4.1e-25 87.4 0.2 8.1e-25 86.5 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Suf PF05843.9 AET37815.1 - 0.27 10.9 15.2 0.73 9.5 2.9 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 AET37815.1 - 1 7.4 38.2 0.11 10.6 7.9 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 AET37815.1 - 2.2 8.0 28.6 4.3 7.1 6.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hom_end_hint PF05203.11 AET37816.1 - 1 9.0 4.9 1.6 8.3 3.4 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint DUF1311 PF07007.7 AET37816.1 - 1.3 9.1 6.6 0.76 9.9 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) Kelch_3 PF13415.1 AET37818.1 - 2.5e-35 119.8 2.1 3e-06 27.2 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 AET37818.1 - 1.2e-31 108.1 8.1 5.5e-05 23.0 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 AET37818.1 - 2.2e-24 84.9 8.0 9.3e-06 25.3 0.3 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 AET37818.1 - 9.8e-23 79.3 5.8 2.4e-06 27.4 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 AET37818.1 - 1.4e-20 72.5 0.3 3.4e-08 32.9 0.1 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 AET37818.1 - 5e-10 38.7 3.5 0.26 11.1 0.0 6.6 7 0 0 7 7 7 3 Kelch motif HALZ PF02183.13 AET37818.1 - 3.9 7.2 39.2 0.1 12.3 0.9 6.7 5 2 2 7 7 7 0 Homeobox associated leucine zipper ApoO PF09769.4 AET37822.1 - 4.7e-38 130.3 0.0 7.3e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein O BRCT PF00533.21 AET37823.1 - 3e-23 81.7 10.6 3.4e-06 27.1 0.1 6.2 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AET37823.1 - 5.1e-20 71.0 4.8 2.2e-14 53.0 0.2 4.2 5 0 0 5 5 5 2 twin BRCT domain Cir_N PF10197.4 AET37824.1 - 0.0075 16.2 1.0 0.0075 16.2 0.7 2.1 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF2454 PF10521.4 AET37824.1 - 0.19 10.6 0.6 0.23 10.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) DUF3602 PF12223.3 AET37824.1 - 3.3 8.1 7.2 2.7 8.4 2.9 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3602) CRM1_C PF08767.6 AET37825.1 - 3.4e-131 436.9 2.7 3.4e-131 436.9 1.8 3.3 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 AET37825.1 - 5.8e-38 130.1 6.0 5.8e-38 130.1 4.2 4.1 5 1 0 6 6 6 1 Exportin 1-like protein IBN_N PF03810.14 AET37825.1 - 1.8e-13 50.1 2.3 8.7e-13 48.0 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Ribosomal_L3 PF00297.17 AET37826.1 - 6.6e-41 140.4 1.4 1.2e-39 136.3 1.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L6 PF00347.18 AET37827.1 - 1.1e-22 80.3 0.7 9.6e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S4 PF00163.14 AET37828.1 - 4.5e-22 78.2 1.9 7e-22 77.6 1.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AET37828.1 - 1.3e-11 43.7 0.0 4.4e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.6 AET37828.1 - 0.0039 15.6 0.0 0.0046 15.4 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus Latent membrane protein 2 RRM_1 PF00076.17 AET37829.1 - 0.0024 17.4 0.1 0.011 15.3 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 AET37830.1 - 0.044 13.6 0.0 1.8 8.5 0.0 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.27 AET37831.1 - 1.7e-12 46.6 9.7 0.0012 18.6 0.0 6.3 8 0 0 8 8 8 3 WD domain, G-beta repeat LuxE PF04443.7 AET37831.1 - 0.061 12.0 0.0 0.095 11.3 0.0 1.2 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE Pex24p PF06398.6 AET37832.1 - 1.5e-76 257.5 0.8 2e-76 257.1 0.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin NAAA-beta PF15508.1 AET37832.1 - 0.047 14.0 0.1 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF639 PF04842.7 AET37832.1 - 0.091 10.9 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Lectin_C PF00059.16 AET37833.1 - 0.00013 22.5 0.3 0.038 14.6 0.3 2.6 2 0 0 2 2 2 2 Lectin C-type domain DIE2_ALG10 PF04922.7 AET37834.1 - 1.3e-114 383.2 36.4 1.6e-114 382.8 25.3 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family SMI1_KNR4 PF09346.5 AET37835.1 - 6e-38 129.7 0.0 1.7e-37 128.3 0.0 1.8 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Spo12 PF05032.7 AET37836.1 - 1.3e-19 69.4 4.5 1.3e-19 69.4 3.1 2.3 2 0 0 2 2 2 1 Spo12 family Ank_2 PF12796.2 AET37837.1 - 1.8e-48 162.7 5.3 5.8e-19 68.2 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 AET37837.1 - 8.7e-36 119.9 0.7 3.6e-08 32.8 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 AET37837.1 - 6.6e-34 115.6 4.1 7.8e-09 35.8 0.1 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET37837.1 - 9.8e-32 105.8 0.7 3e-05 23.8 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 AET37837.1 - 2.9e-30 103.5 1.5 6.7e-07 29.3 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ion_trans PF00520.26 AET37838.1 - 4.7e-87 290.4 100.9 2.1e-33 115.2 7.2 5.8 6 0 0 6 6 6 5 Ion transport protein EF-hand_6 PF13405.1 AET37838.1 - 0.02 14.7 0.2 0.11 12.4 0.1 2.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 AET37838.1 - 0.024 13.9 0.3 0.024 13.9 0.2 2.4 2 0 0 2 2 2 0 EF hand Gpi1 PF05024.10 AET37839.1 - 2.3e-48 164.4 17.2 2.3e-48 164.4 11.9 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) MRP-S33 PF08293.6 AET37840.1 - 1.3e-32 111.6 0.4 1.4e-32 111.5 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribosomal_S2 PF00318.15 AET37841.1 - 6.6e-40 136.5 0.0 9.2e-20 70.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Glucan_synthase PF02364.10 AET37842.1 - 1.3e-299 995.7 1.2 2e-299 995.1 0.8 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 AET37842.1 - 2.2e-30 104.9 2.2 6.3e-30 103.4 1.5 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF4640 PF15480.1 AET37842.1 - 0.67 9.4 0.0 1.1 8.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) TPR_11 PF13414.1 AET37843.1 - 5.5e-18 64.3 0.2 8e-18 63.8 0.1 1.2 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 AET37843.1 - 5e-12 44.8 0.4 4e-07 29.3 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 AET37843.1 - 3.6e-10 38.9 0.1 2.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 AET37843.1 - 1.3e-07 30.9 0.0 0.00057 19.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 AET37843.1 - 4.3e-07 29.7 0.0 0.0014 18.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AET37843.1 - 1e-06 28.7 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AET37843.1 - 3.6e-06 26.7 0.2 0.0017 18.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AET37843.1 - 5.3e-05 22.7 0.4 0.0015 18.1 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 AET37843.1 - 5.4e-05 23.4 0.0 8.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 AET37843.1 - 0.0033 17.9 0.0 0.38 11.5 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AET37843.1 - 0.0033 18.0 0.0 0.005 17.4 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 AET37843.1 - 0.012 15.4 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 AET37843.1 - 0.043 13.6 0.2 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat UPF0029 PF01205.14 AET37844.1 - 1.2e-29 102.2 0.0 1.8e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 AET37844.1 - 1.1e-11 44.6 0.1 2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain WD40 PF00400.27 AET37846.1 - 1.3e-56 186.5 16.0 6.2e-13 48.0 0.2 12.5 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 AET37846.1 - 5.6e-25 87.3 0.0 8.8e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 AET37846.1 - 3.2e-09 36.7 6.1 0.0006 19.5 0.1 6.2 5 1 3 8 8 8 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AET37846.1 - 7.9e-07 27.5 3.1 0.23 9.5 0.0 4.4 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 AET37846.1 - 2.3e-06 26.9 0.3 1.6 7.7 0.0 4.4 3 1 1 4 4 4 3 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 AET37846.1 - 0.00021 20.7 0.4 2.1 7.6 0.2 3.8 3 1 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Proteasome_A_N PF10584.4 AET37846.1 - 0.15 11.3 1.8 2.5 7.4 0.2 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Atx10homo_assoc PF09759.4 AET37847.1 - 2.6e-38 129.8 0.9 7.4e-38 128.3 0.6 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain DUF2363 PF10155.4 AET37847.1 - 0.91 9.4 5.3 12 5.8 0.2 3.2 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2363) Thr_synth_N PF14821.1 AET37848.1 - 3.4e-26 91.0 0.0 1e-25 89.5 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 AET37848.1 - 1.4e-17 63.9 0.0 2.1e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACCA PF03255.9 AET37849.1 - 0.017 14.7 1.0 0.28 10.7 0.0 2.8 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ribosomal_L9_N PF01281.14 AET37850.1 - 2.8e-05 23.2 0.2 0.00017 20.7 0.2 2.1 1 1 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L14e PF01929.12 AET37850.1 - 0.052 13.8 0.3 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L14 DUF1682 PF07946.9 AET37851.1 - 1.2e-83 280.6 10.2 1.5e-83 280.3 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ank_5 PF13857.1 AET37852.1 - 2.7e-17 62.3 0.1 2.6e-12 46.5 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AET37852.1 - 4.4e-12 46.1 0.2 3.2e-09 37.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AET37852.1 - 2.6e-11 43.7 0.4 7.2e-07 29.5 0.2 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET37852.1 - 3e-08 33.1 0.7 0.00032 20.6 0.1 4.1 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 AET37852.1 - 5.3e-08 32.2 4.1 6.4e-05 22.5 0.2 4.1 4 0 0 4 4 4 1 Ankyrin repeat MRG PF05712.8 AET37852.1 - 0.034 13.0 0.6 0.57 9.0 0.1 2.2 2 0 0 2 2 2 0 MRG Peptidase_M76 PF09768.4 AET37853.1 - 8e-75 250.0 3.4 9.8e-75 249.7 2.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family Dicty_spore_N PF04562.7 AET37853.1 - 0.38 11.0 4.3 0.11 12.8 0.5 1.9 2 1 0 2 2 2 0 Dictyostelium spore coat protein, N terminus MBOAT PF03062.14 AET37854.1 - 1.7e-51 175.2 43.0 3.1e-51 174.4 29.8 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 AET37854.1 - 0.0009 19.2 4.3 0.0032 17.5 3.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WBS_methylT PF12589.3 AET37855.1 - 1.1e-15 57.9 7.3 2.3e-15 56.8 5.0 1.7 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 AET37855.1 - 2.9e-13 50.1 0.0 6.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET37855.1 - 9.7e-10 38.2 0.0 1.8e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AET37855.1 - 1.1e-07 31.7 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET37855.1 - 5.9e-07 29.7 0.0 2.3e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AET37855.1 - 7e-07 29.6 0.0 2.3e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET37855.1 - 1.5e-06 28.7 0.0 3.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET37855.1 - 3.3e-05 23.8 0.0 6.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AET37855.1 - 5.1e-05 22.8 0.0 0.00071 19.1 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 AET37855.1 - 0.00013 21.1 0.0 0.00032 19.8 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 AET37855.1 - 0.00056 19.1 0.3 0.0048 16.0 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 AET37855.1 - 0.0022 17.3 0.0 0.0064 15.8 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.8 AET37855.1 - 0.0055 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 AET37855.1 - 0.042 13.5 0.2 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TPMT PF05724.6 AET37855.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ribosomal_L19 PF01245.15 AET37856.1 - 3.6e-13 49.2 0.1 5.3e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 HIG_1_N PF04588.8 AET37857.1 - 0.00012 21.7 0.5 0.00022 20.8 0.4 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Peptidase_S8 PF00082.17 AET37858.1 - 5.6e-47 160.2 1.7 8.4e-47 159.6 1.2 1.2 1 0 0 1 1 1 1 Subtilase family PAZ_siRNAbind PF12212.3 AET37858.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain Tim17 PF02466.14 AET37859.1 - 1.1e-26 93.3 2.4 1.3e-26 93.0 1.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ACC_central PF08326.7 AET37860.1 - 4.9e-265 881.1 0.1 6.5e-265 880.6 0.1 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 AET37860.1 - 3.1e-176 586.5 0.0 4.2e-176 586.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 AET37860.1 - 9e-51 172.1 0.0 1.8e-50 171.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AET37860.1 - 2.2e-25 88.9 0.0 4.8e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AET37860.1 - 2.4e-20 72.5 0.0 6.6e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 AET37860.1 - 1.4e-14 53.5 0.0 3.5e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 AET37860.1 - 4.8e-09 36.2 0.0 1.8e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AET37860.1 - 6.2e-09 35.0 0.0 0.00071 18.4 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AET37860.1 - 0.00012 22.0 0.0 0.00066 19.5 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AET37860.1 - 0.00033 20.0 0.0 0.00085 18.7 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 AET37860.1 - 0.054 12.8 0.0 0.41 9.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Dus PF01207.12 AET37861.1 - 3.6e-52 177.1 0.0 1.7e-51 174.9 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF1708 PF08101.6 AET37862.1 - 4.4e-73 246.5 4.7 8.1e-73 245.6 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SPX PF03105.14 AET37864.1 - 8.8e-42 143.7 0.2 1.6e-41 142.9 0.1 1.4 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 AET37864.1 - 4.7e-28 98.2 42.9 6.3e-28 97.8 29.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 AET37864.1 - 3.1e-15 55.6 44.2 1.4e-14 53.5 13.4 2.4 1 1 1 2 2 2 2 Citrate transporter PRK PF00485.13 AET37865.1 - 6.6e-62 208.5 0.0 9.6e-62 207.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 AET37865.1 - 2.7e-33 114.9 0.1 6.4e-33 113.7 0.0 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 AET37865.1 - 7.5e-09 36.4 0.0 1.9e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AET37865.1 - 2.5e-08 34.2 0.0 7.6e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 AET37865.1 - 0.0025 17.4 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 AET37865.1 - 0.005 15.9 0.0 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin CoaE PF01121.15 AET37865.1 - 0.031 13.6 0.1 6.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_33 PF13671.1 AET37865.1 - 0.034 14.0 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.1 AET37865.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain dNK PF01712.14 AET37865.1 - 0.15 11.9 0.7 15 5.5 0.0 2.7 3 0 0 3 3 3 0 Deoxynucleoside kinase HA2 PF04408.18 AET37866.1 - 3.9e-16 58.9 0.0 1.5e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AET37866.1 - 1e-15 57.5 0.0 2.4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AET37866.1 - 1.5e-14 53.5 0.0 4e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AET37866.1 - 1.8e-06 27.5 0.1 4.1e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 AET37866.1 - 0.00013 20.9 0.0 0.00027 19.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 AET37866.1 - 0.00021 21.4 0.1 0.00069 19.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 AET37866.1 - 0.0056 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain KaiC PF06745.8 AET37866.1 - 0.014 14.4 0.0 0.25 10.4 0.0 2.6 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.1 AET37866.1 - 0.037 13.7 0.1 0.087 12.5 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 AET37866.1 - 0.04 13.7 0.1 3.5 7.4 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 AET37866.1 - 0.058 13.6 0.3 0.6 10.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 AET37866.1 - 0.069 12.7 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 AET37866.1 - 0.078 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PFK PF00365.15 AET37867.1 - 1.5e-164 545.8 3.3 3e-124 413.5 2.2 2.2 2 0 0 2 2 2 2 Phosphofructokinase Inp1 PF12634.2 AET37868.1 - 3.2e-30 104.7 0.5 7.2e-30 103.5 0.1 1.8 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 Porin_3 PF01459.17 AET37869.1 - 1.8e-84 283.3 0.2 2e-84 283.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Med9 PF07544.8 AET37870.1 - 9.6e-21 73.3 0.2 1.3e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Peptidase_M9_N PF08453.5 AET37870.1 - 0.034 13.4 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M9 N-terminal DUF3610 PF12272.3 AET37870.1 - 0.085 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) ERG2_Sigma1R PF04622.7 AET37871.1 - 1.3e-85 286.1 0.3 1.5e-85 285.8 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Whi5 PF08528.6 AET37872.1 - 1.4e-08 34.0 0.4 2.8e-08 33.1 0.3 1.5 1 0 0 1 1 1 1 Whi5 like DUF3719 PF12516.3 AET37872.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) LCAT PF02450.10 AET37873.1 - 1.7e-122 409.1 0.0 2.3e-122 408.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 AET37873.1 - 0.0026 17.5 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 AET37873.1 - 0.032 13.5 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) DUF726 PF05277.7 AET37873.1 - 0.083 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF900 PF05990.7 AET37873.1 - 0.13 11.5 0.1 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Autophagy_N PF03986.8 AET37874.1 - 3.4e-43 146.9 0.6 3.4e-43 146.9 0.4 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 AET37874.1 - 9.1e-23 80.2 0.4 2.6e-22 78.7 0.3 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 AET37874.1 - 9.3e-15 53.4 0.9 1.7e-14 52.6 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal 5_nucleotid_C PF02872.13 AET37874.1 - 0.049 13.6 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain DUF1940 PF09155.5 AET37874.1 - 0.088 12.6 0.5 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) XPA_C PF05181.7 AET37875.1 - 1.6e-25 88.4 0.1 4.5e-25 86.9 0.1 1.9 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 AET37875.1 - 0.0005 19.6 0.4 0.0005 19.6 0.3 1.8 2 0 0 2 2 2 1 XPA protein N-terminal VHS PF00790.14 AET37876.1 - 1.4e-38 131.7 0.1 3.2e-38 130.5 0.1 1.7 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 AET37876.1 - 6.4e-19 67.6 1.8 6.4e-19 67.6 1.2 2.3 2 1 0 2 2 2 1 FYVE zinc finger UIM PF02809.15 AET37876.1 - 2.2e-06 26.7 5.1 0.0062 16.0 0.5 3.4 2 0 0 2 2 2 2 Ubiquitin interaction motif BLVR PF06375.6 AET37876.1 - 0.0003 20.6 2.4 0.027 14.3 0.6 2.7 2 0 0 2 2 2 2 Bovine leukaemia virus receptor (BLVR) FYVE_2 PF02318.11 AET37876.1 - 0.0014 18.5 1.8 0.0014 18.5 1.3 2.9 3 0 0 3 3 3 1 FYVE-type zinc finger zf-AN1 PF01428.11 AET37876.1 - 0.4 10.5 9.8 0.54 10.1 4.8 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger Rot1 PF10681.4 AET37877.1 - 8.2e-94 312.8 0.0 9.4e-94 312.6 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Cyclin_N PF00134.18 AET37878.1 - 1.5e-37 127.9 0.0 3.3e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain COBRA PF04833.10 AET37878.1 - 0.022 14.5 0.5 0.046 13.4 0.3 1.5 1 0 0 1 1 1 0 COBRA-like protein ApoB100_C PF12491.3 AET37878.1 - 0.037 13.6 2.1 0.14 11.8 0.2 2.6 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal BBP1_C PF15272.1 AET37880.1 - 1.5e-52 177.9 26.2 1.5e-52 177.9 18.2 2.0 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.1 AET37880.1 - 2.8e-41 141.2 0.8 2.8e-41 141.2 0.6 2.7 2 1 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein DUF3053 PF11254.3 AET37880.1 - 0.023 13.9 1.7 0.044 13.0 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) DUF2392 PF10288.4 AET37881.1 - 0.0025 18.1 0.2 0.014 15.7 0.1 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) AAA_13 PF13166.1 AET37881.1 - 0.0046 15.5 36.9 0.26 9.7 21.0 2.6 1 1 2 3 3 3 2 AAA domain DUF1664 PF07889.7 AET37881.1 - 1.3 8.8 28.9 0.93 9.3 0.2 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Fer2 PF00111.22 AET37882.1 - 8.3e-13 47.8 2.7 1.1e-12 47.4 1.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain V-SNARE_C PF12352.3 AET37883.1 - 8.4e-16 57.8 3.2 8.4e-16 57.8 2.2 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 AET37883.1 - 1.4e-14 53.9 1.3 1.4e-14 53.9 0.9 2.1 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 AET37883.1 - 5.1e-05 22.9 7.0 0.00067 19.3 0.2 3.1 2 1 1 3 3 3 1 Sec20 DUF1744 PF08490.7 AET37883.1 - 0.00095 17.8 0.8 0.062 11.8 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1744) Fzo_mitofusin PF04799.8 AET37883.1 - 0.016 14.6 1.7 0.016 14.6 1.2 1.8 2 0 0 2 2 2 0 fzo-like conserved region DegS PF05384.6 AET37883.1 - 0.063 12.4 5.3 0.049 12.8 0.6 2.5 2 2 1 3 3 3 0 Sensor protein DegS YqjK PF13997.1 AET37883.1 - 0.065 13.4 0.8 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 YqjK-like protein CENP-F_leu_zip PF10473.4 AET37883.1 - 0.25 11.1 5.9 1.9 8.3 4.0 2.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 AET37883.1 - 0.77 9.8 8.8 11 6.1 2.2 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.8 AET37883.1 - 1.1 8.9 7.7 0.64 9.6 0.4 3.2 1 1 2 3 3 3 0 Nsp1-like C-terminal region DUF972 PF06156.8 AET37883.1 - 3.5 8.0 6.4 1.6 9.1 0.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Glyco_hydro_63 PF03200.11 AET37884.1 - 2.8e-06 25.5 5.7 0.00017 19.5 0.1 3.7 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase DUF1903 PF08991.5 AET37886.1 - 2.8e-21 75.4 4.7 2.8e-21 75.4 3.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1903) Cmc1 PF08583.5 AET37886.1 - 0.64 9.8 8.1 1.1 9.0 0.8 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_L36e PF01158.13 AET37887.1 - 1.1e-37 127.9 3.8 1.2e-37 127.8 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 AET37887.1 - 0.092 11.8 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 LemA family Ribosomal_L28 PF00830.14 AET37888.1 - 1.1e-22 79.6 0.9 2.6e-22 78.4 0.6 1.7 1 0 0 1 1 1 1 Ribosomal L28 family RabGAP-TBC PF00566.13 AET37889.1 - 2.2e-50 171.1 0.4 2.2e-50 171.1 0.3 2.8 4 0 0 4 4 4 1 Rab-GTPase-TBC domain DivIC PF04977.10 AET37889.1 - 1 8.8 26.4 1.8 8.0 1.8 4.6 3 1 1 4 4 4 0 Septum formation initiator RQC PF09382.5 AET37890.1 - 1.3e-27 95.5 0.2 3.3e-27 94.2 0.1 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 AET37890.1 - 1.2e-23 83.4 0.0 3.6e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET37890.1 - 1.6e-19 69.5 0.0 1.6e-17 63.0 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_Sgs1 PF11408.3 AET37890.1 - 2e-06 27.5 0.0 6.6e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase WD40 PF00400.27 AET37891.1 - 3.6e-17 61.5 16.1 4.9e-07 29.3 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Ribosomal_S17 PF00366.15 AET37892.1 - 1.5e-15 56.9 0.3 2.6e-15 56.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Rhomboid PF01694.17 AET37893.1 - 4.8e-19 68.8 9.2 4.8e-19 68.8 6.4 1.4 2 0 0 2 2 2 1 Rhomboid family OAD_beta PF03977.8 AET37893.1 - 0.024 13.3 1.0 0.032 12.9 0.0 1.6 2 0 0 2 2 2 0 Na+-transporting oxaloacetate decarboxylase beta subunit TIM21 PF08294.6 AET37893.1 - 0.03 13.9 0.4 0.059 13.0 0.3 1.4 1 0 0 1 1 1 0 TIM21 DUF3925 PF13063.1 AET37893.1 - 0.29 11.1 4.1 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) UAA PF08449.6 AET37894.1 - 3.8e-74 249.3 13.7 4.4e-74 249.1 9.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 AET37894.1 - 1.4e-08 34.7 7.1 1.4e-08 34.7 4.9 3.5 2 2 1 3 3 3 1 EamA-like transporter family TPT PF03151.11 AET37894.1 - 2e-08 34.0 7.8 2e-08 34.0 5.4 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 AET37894.1 - 0.003 17.7 17.8 0.017 15.3 4.9 3.0 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Bac_rhamnosid PF05592.6 AET37895.1 - 0.036 12.2 0.0 0.073 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase WWE PF02825.15 AET37896.1 - 0.0016 17.8 1.2 0.0025 17.1 0.2 1.7 2 0 0 2 2 2 1 WWE domain RINGv PF12906.2 AET37896.1 - 0.0021 18.0 7.8 0.006 16.5 5.4 1.8 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 AET37896.1 - 0.062 13.2 9.6 0.039 13.9 3.8 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain Sgf11 PF08209.6 AET37896.1 - 0.084 12.1 0.2 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf-RING_2 PF13639.1 AET37896.1 - 0.15 11.9 5.9 0.15 11.9 1.8 2.5 2 0 0 2 2 2 0 Ring finger domain RasGAP_C PF03836.10 AET37898.1 - 1.7e-31 108.7 1.1 1.7e-31 108.7 0.8 2.4 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 AET37898.1 - 5.9e-15 55.4 1.7 5.9e-15 55.4 1.2 2.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 AET37898.1 - 3.4e-10 39.9 0.1 1.5e-08 34.6 0.0 3.6 3 0 0 3 3 3 1 Calponin homology (CH) domain IQ PF00612.22 AET37898.1 - 1.9e-06 27.0 12.7 4.3 7.2 0.0 7.1 6 0 0 6 6 6 4 IQ calmodulin-binding motif TBCC PF07986.7 AET37899.1 - 1.1e-05 24.8 4.8 2.1e-05 23.9 3.3 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C HSP90 PF00183.13 AET37900.1 - 2e-253 841.6 35.0 2.4e-253 841.3 24.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 AET37900.1 - 1.6e-10 40.6 0.0 2.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AET37900.1 - 1.7e-10 40.6 0.1 5.6e-10 39.0 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2435 PF10363.4 AET37901.1 - 1.3e-31 108.3 2.5 7.9e-30 102.6 0.0 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 AET37901.1 - 0.067 13.4 0.1 2.1 8.7 0.0 3.0 3 1 0 3 3 3 0 HEAT repeats HEAT PF02985.17 AET37901.1 - 0.1 12.7 0.0 4.2 7.7 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Ank PF00023.25 AET37902.1 - 1.6e-19 68.6 0.2 1.1e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 AET37902.1 - 2.5e-18 66.1 0.0 5.6e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AET37902.1 - 1.2e-16 60.2 0.7 7.3e-08 32.4 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET37902.1 - 2.5e-14 51.9 0.2 1.3e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 AET37902.1 - 3.1e-14 53.0 0.0 1.9e-13 50.4 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PAZ PF02170.17 AET37902.1 - 0.041 13.1 0.2 0.057 12.7 0.1 1.2 1 0 0 1 1 1 0 PAZ domain XPA_N PF01286.13 AET37902.1 - 0.28 10.8 1.1 1.5 8.5 0.0 2.5 3 0 0 3 3 3 0 XPA protein N-terminal eIF-5_eIF-2B PF01873.12 AET37903.1 - 4.1e-45 152.4 0.2 7.9e-45 151.5 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.10 AET37903.1 - 0.0091 15.6 2.2 0.046 13.3 0.0 3.2 3 1 1 4 4 4 1 Translation initiation factor IF-2, N-terminal region PDDEXK_4 PF14281.1 AET37903.1 - 0.042 13.7 0.0 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily TF_Zn_Ribbon PF08271.7 AET37903.1 - 0.095 12.0 0.2 0.24 10.7 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Prok-RING_2 PF14445.1 AET37903.1 - 0.13 12.1 0.1 3.1 7.8 0.0 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 2 Pkinase PF00069.20 AET37905.1 - 4.4e-24 85.0 0.0 3.5e-23 82.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37905.1 - 8e-11 41.5 0.0 3.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TIP49 PF06068.8 AET37906.1 - 7.2e-178 591.3 4.3 8.6e-178 591.0 3.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 AET37906.1 - 1.3e-08 35.1 0.5 4.9e-05 23.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AET37906.1 - 4e-07 29.3 4.0 0.00065 18.8 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 AET37906.1 - 2e-05 23.6 0.1 4e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 AET37906.1 - 3.9e-05 23.7 0.9 0.068 13.3 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 AET37906.1 - 0.00013 22.0 0.0 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 AET37906.1 - 0.00018 21.4 0.3 2.3 8.1 0.0 3.4 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 AET37906.1 - 0.0047 16.1 0.8 0.12 11.5 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 AET37906.1 - 0.007 15.7 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AET37906.1 - 0.0076 15.9 0.3 1.7 8.3 0.0 3.1 2 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 AET37906.1 - 0.0079 16.1 0.1 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AET37906.1 - 0.046 14.0 0.1 0.16 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AET37906.1 - 0.056 12.9 0.0 8.6 5.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 AET37906.1 - 0.094 13.5 0.1 0.27 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AET37906.1 - 0.098 11.7 0.3 0.22 10.6 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 AET37906.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_C PF00137.16 AET37907.1 - 9.8e-27 92.6 29.9 5.9e-15 54.9 4.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 AET37907.1 - 0.0018 17.7 3.2 0.0018 17.7 2.2 2.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Mis14 PF08641.7 AET37908.1 - 1.4e-27 96.4 4.7 1.4e-27 96.4 3.3 1.5 2 0 0 2 2 2 1 Kinetochore protein Mis14 like HWE_HK PF07536.9 AET37908.1 - 0.12 12.8 0.9 16 5.9 0.1 3.1 2 1 0 3 3 3 0 HWE histidine kinase SNARE PF05739.14 AET37909.1 - 2.2e-15 56.0 8.2 7e-15 54.4 5.7 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 AET37909.1 - 1.5e-05 25.0 21.7 2.9e-05 24.1 5.7 2.4 2 1 0 2 2 2 2 Syntaxin Synaptobrevin PF00957.16 AET37909.1 - 0.00028 20.4 3.2 0.00028 20.4 2.2 2.1 2 0 0 2 2 2 1 Synaptobrevin Thr_dehydrat_C PF00585.13 AET37909.1 - 0.0032 17.0 2.8 0.019 14.5 0.0 3.0 3 0 0 3 3 3 1 C-terminal regulatory domain of Threonine dehydratase T2SF PF00482.18 AET37909.1 - 0.0034 17.2 0.4 0.0034 17.2 0.3 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F Baculo_PEP_C PF04513.7 AET37909.1 - 0.052 13.3 9.5 0.31 10.8 1.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF668 PF05003.7 AET37909.1 - 0.076 13.2 0.6 0.23 11.7 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF668) AATase PF07247.7 AET37909.1 - 0.093 11.2 3.7 0.54 8.7 0.3 2.1 2 0 0 2 2 2 0 Alcohol acetyltransferase OppC_N PF12911.2 AET37909.1 - 0.36 10.2 2.0 0.73 9.2 1.4 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CRISPR_Cse1 PF09481.5 AET37909.1 - 0.4 9.3 7.9 0.13 11.0 1.2 2.1 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Allexi_40kDa PF05549.6 AET37909.1 - 0.43 9.8 7.8 1.2 8.3 0.4 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF2116 PF09889.4 AET37909.1 - 0.57 10.0 2.2 1.6 8.6 1.5 1.7 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Herpes_US9 PF06072.6 AET37909.1 - 0.61 9.9 2.7 1.3 8.9 1.8 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4179 PF13786.1 AET37909.1 - 2.9 8.1 8.8 1.5 9.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF1664 PF07889.7 AET37909.1 - 3.8 7.3 9.4 0.6 9.9 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PBP1_TM PF14812.1 AET37909.1 - 5.1 7.4 8.0 0.67 10.2 0.1 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 AET37909.1 - 6.7 6.8 9.0 0.23 11.5 0.5 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) adh_short_C2 PF13561.1 AET37910.1 - 3e-18 66.4 0.0 9.5e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 AET37910.1 - 2.8e-17 63.0 0.0 5.3e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 AET37910.1 - 2.6e-16 59.4 0.0 8e-16 57.8 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 AET37910.1 - 7.8e-11 41.8 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 AET37910.1 - 5.8e-06 26.3 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AET37910.1 - 0.0017 18.0 0.0 0.0049 16.5 0.0 1.8 1 0 0 1 1 1 1 KR domain zf-C2H2 PF00096.21 AET37911.1 - 2.6e-10 39.9 8.4 8e-05 22.7 0.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET37911.1 - 1.7e-09 37.4 6.6 2.8e-09 36.7 1.5 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET37911.1 - 1.5e-06 28.1 7.2 0.00061 19.9 0.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 AET37911.1 - 0.013 15.7 10.4 0.015 15.4 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 AET37911.1 - 0.015 15.5 1.3 0.015 15.5 0.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 AET37911.1 - 0.048 13.5 1.4 0.091 12.6 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AET37911.1 - 0.13 12.4 0.4 0.13 12.4 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FimP PF09766.4 AET37911.1 - 0.17 10.9 13.9 0.077 12.0 7.8 1.7 2 0 0 2 2 2 0 Fms-interacting protein PAT1 PF09770.4 AET37911.1 - 5.8 5.0 36.5 8.5 4.4 25.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cauli_DNA-bind PF03310.8 AET37911.1 - 7.4 6.4 8.0 27 4.6 0.3 2.8 3 0 0 3 3 3 0 Caulimovirus DNA-binding protein YppG PF14179.1 AET37912.1 - 0.97 10.0 30.0 2.8 8.5 5.4 2.2 2 0 0 2 2 2 0 YppG-like protein mRNA_triPase PF02940.10 AET37913.1 - 3.4e-58 196.9 0.8 5.6e-58 196.1 0.6 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.21 AET37914.1 - 6.9e-26 90.9 0.0 9.4e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AET37914.1 - 1.7e-07 31.3 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AET37914.1 - 0.0043 16.1 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AET37914.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 ArsB PF02040.10 AET37914.1 - 0.022 13.7 0.1 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Arsenical pump membrane protein ABC_tran PF00005.22 AET37916.1 - 2.2e-47 160.8 0.2 4.8e-26 91.6 0.0 4.5 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 AET37916.1 - 9.3e-16 58.6 5.6 8.7e-07 29.1 0.1 4.1 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 AET37916.1 - 5e-12 45.5 0.0 0.0023 17.2 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AET37916.1 - 2.9e-08 34.2 0.0 0.00081 19.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain Chromo PF00385.19 AET37916.1 - 4e-08 32.8 3.4 7.8e-08 31.8 2.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 AET37916.1 - 7.7e-08 31.7 1.0 0.0042 16.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AET37916.1 - 5.8e-07 30.3 0.0 0.011 16.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 AET37916.1 - 9.6e-07 28.1 0.2 0.004 16.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 AET37916.1 - 1e-06 28.4 2.6 0.29 10.5 0.1 4.5 4 1 0 4 4 4 2 AAA-like domain AAA_15 PF13175.1 AET37916.1 - 1.3e-06 27.7 0.1 0.14 11.1 0.0 3.5 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 AET37916.1 - 1.4e-06 28.4 0.0 0.039 14.1 0.0 3.4 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 AET37916.1 - 2.9e-06 27.2 0.0 0.014 15.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 AET37916.1 - 4.6e-05 23.8 0.0 0.078 13.4 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 AET37916.1 - 0.00019 20.3 0.4 0.41 9.3 0.0 2.7 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 AET37916.1 - 0.00028 20.6 0.1 0.12 12.0 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 AET37916.1 - 0.00057 20.0 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.12 AET37916.1 - 0.00067 19.5 4.2 0.091 12.5 0.1 3.7 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_33 PF13671.1 AET37916.1 - 0.0011 18.8 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AET37916.1 - 0.0012 18.5 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_13 PF13166.1 AET37916.1 - 0.0019 16.7 0.1 0.58 8.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 AET37916.1 - 0.0023 17.7 0.1 2.6 8.0 0.0 3.5 2 2 1 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 AET37916.1 - 0.0046 16.9 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 AET37916.1 - 0.0049 16.6 0.7 0.36 10.6 0.0 3.6 4 0 0 4 4 4 1 Dynamin family AAA PF00004.24 AET37916.1 - 0.0079 16.3 0.0 3.6 7.7 0.0 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 AET37916.1 - 0.02 14.4 0.3 6.9 6.1 0.0 3.0 4 0 0 4 4 2 0 AAA domain AAA_18 PF13238.1 AET37916.1 - 0.029 14.6 4.8 0.1 12.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 AET37916.1 - 0.03 14.0 0.1 5.4 6.6 0.1 3.0 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.4 AET37916.1 - 0.036 13.5 0.1 4.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 AET37916.1 - 0.036 11.4 0.9 2.9 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_14 PF13173.1 AET37916.1 - 0.04 13.8 0.0 1.9 8.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AET37916.1 - 0.047 13.6 1.3 0.8 9.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.8 AET37916.1 - 0.048 12.5 0.4 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 AET37916.1 - 0.051 12.9 0.0 9.9 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 AET37916.1 - 0.055 12.5 0.1 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 AET37916.1 - 0.087 12.2 1.2 6.4 6.1 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family cobW PF02492.14 AET37916.1 - 0.088 12.2 0.1 22 4.4 0.0 3.3 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain MutS_V PF00488.16 AET37916.1 - 0.091 12.1 0.2 8.3 5.7 0.0 2.4 2 0 0 2 2 2 0 MutS domain V Thymidylate_kin PF02223.12 AET37916.1 - 0.44 9.8 3.3 1 8.6 0.0 3.2 4 0 0 4 4 3 0 Thymidylate kinase ABC_tran_2 PF12848.2 AET37916.1 - 4.2 7.2 8.6 0.17 11.7 0.5 2.5 2 0 0 2 2 2 0 ABC transporter MoCF_biosynth PF00994.19 AET37917.1 - 6.4e-28 96.9 0.0 1e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF4217 PF13959.1 AET37917.1 - 0.11 12.0 0.1 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) Polysacc_synt_4 PF04669.8 AET37918.1 - 5.1e-20 71.6 1.3 4.5e-19 68.5 0.9 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis Cation_efflux PF01545.16 AET37919.1 - 1.8e-50 171.6 4.0 2.2e-50 171.3 2.8 1.1 1 0 0 1 1 1 1 Cation efflux family GCR1_C PF12550.3 AET37922.1 - 4.7e-23 80.8 1.4 4.7e-23 80.8 1.0 2.1 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Med15 PF09606.5 AET37922.1 - 1.8e-05 23.1 75.1 1.8e-05 23.1 52.0 1.5 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Rtf2 PF04641.7 AET37922.1 - 0.017 14.3 21.9 0.037 13.2 15.2 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Pex16 PF08610.5 AET37922.1 - 1 8.3 20.6 2.1 7.2 14.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Zip PF02535.17 AET37922.1 - 6.7 5.6 8.0 13 4.7 5.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0061 PF02696.9 AET37923.1 - 1.3e-145 485.4 0.1 1.6e-145 485.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3422 PF11902.3 AET37923.1 - 0.027 13.3 0.1 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Lon_C PF05362.8 AET37925.1 - 6.9e-39 133.2 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 AET37925.1 - 3.4e-19 69.3 0.0 7.6e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AET37925.1 - 2.2e-08 33.9 0.0 1.1e-07 31.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) LON PF02190.11 AET37925.1 - 1.1e-06 28.5 0.1 2.9e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 AET37925.1 - 4.4e-06 26.2 0.0 1.2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 AET37925.1 - 0.0001 22.3 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 AET37925.1 - 0.00022 20.3 0.0 0.0031 16.5 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AET37925.1 - 0.00036 21.3 0.0 0.0012 19.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 AET37925.1 - 0.00075 19.1 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AET37925.1 - 0.0017 18.2 0.0 0.0068 16.3 0.0 1.9 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) SMC_N PF02463.14 AET37925.1 - 0.0023 17.1 0.1 0.062 12.5 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 AET37925.1 - 0.0024 17.0 0.0 0.0054 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 AET37925.1 - 0.0028 17.1 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 AET37925.1 - 0.0062 16.6 0.0 0.1 12.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AET37925.1 - 0.012 15.7 0.0 0.082 13.0 0.0 2.5 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 AET37925.1 - 0.015 14.4 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 AET37925.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AET37925.1 - 0.029 13.5 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 AET37925.1 - 0.039 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AET37925.1 - 0.079 13.2 0.0 0.29 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AET37925.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 AET37925.1 - 0.16 11.3 0.0 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.1 AET37925.1 - 0.17 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain TelA PF05816.6 AET37925.1 - 0.43 9.2 2.8 0.3 9.7 0.2 1.9 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) TRP PF06011.7 AET37926.1 - 4.2e-144 480.3 34.7 5.2e-144 480.0 24.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AET37926.1 - 9.7e-45 152.0 0.0 1.5e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 ML-like domain TMEMspv1-c74-12 PF11044.3 AET37926.1 - 0.035 13.6 0.0 0.035 13.6 0.0 3.4 4 0 0 4 4 4 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Rho_Binding PF08912.6 AET37927.1 - 0.69 10.2 3.7 38 4.6 0.0 2.8 2 0 0 2 2 2 0 Rho Binding FtsJ PF01728.14 AET37928.1 - 5.2e-57 192.7 0.0 2e-56 190.8 0.0 1.7 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 AET37928.1 - 3.4e-05 24.3 0.0 0.00014 22.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AET37928.1 - 0.00062 19.5 0.0 0.0019 17.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET37928.1 - 0.0021 17.6 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Ribosomal_L1 PF00687.16 AET37929.1 - 1.3e-45 155.4 2.1 1.5e-45 155.2 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cyclin PF08613.6 AET37930.1 - 1.2e-13 51.6 0.2 2.7e-13 50.5 0.1 1.8 1 1 0 1 1 1 1 Cyclin Arf PF00025.16 AET37931.1 - 2.5e-65 218.9 0.0 2.9e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AET37931.1 - 8.2e-09 34.6 0.9 1.2e-05 24.2 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AET37931.1 - 1.6e-08 35.0 0.0 2.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 AET37931.1 - 1.1e-07 31.3 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 AET37931.1 - 3e-07 29.8 0.0 3.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AET37931.1 - 3.7e-06 26.8 0.0 5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AET37931.1 - 0.00014 21.0 0.0 0.00017 20.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AET37931.1 - 0.022 14.2 0.0 0.38 10.1 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 AET37931.1 - 0.056 12.9 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation WAC_Acf1_DNA_bd PF10537.4 AET37932.1 - 8.7e-37 125.3 0.9 3.5e-36 123.4 0.6 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 AET37932.1 - 8e-13 47.9 1.7 2.3e-11 43.2 0.3 2.5 2 0 0 2 2 2 1 DDT domain WHIM2 PF15613.1 AET37932.1 - 1.2e-05 25.0 0.1 3.5e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Ubiq_cyt_C_chap PF03981.7 AET37933.1 - 4.2e-42 143.3 0.2 6.5e-42 142.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HK PF02110.10 AET37934.1 - 6e-66 222.0 0.6 9.4e-66 221.4 0.4 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 AET37934.1 - 9.3e-57 191.0 0.0 1.4e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 AET37934.1 - 0.058 12.6 0.3 7.6 5.7 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate kinase Mac PF12464.3 AET37934.1 - 0.14 12.1 0.2 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Maltose acetyltransferase LRR_9 PF14580.1 AET37935.1 - 4.8e-07 29.4 0.3 1e-06 28.4 0.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 AET37935.1 - 1.3e-05 24.6 13.8 0.016 14.8 2.0 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AET37935.1 - 0.016 15.1 12.6 5.5 7.4 0.3 4.1 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 AET37935.1 - 0.19 11.4 10.4 1.5 8.6 0.7 3.0 1 1 1 2 2 2 0 Leucine rich repeat LRR_6 PF13516.1 AET37935.1 - 2.4 8.4 12.3 26 5.3 0.0 4.4 4 1 1 5 5 5 0 Leucine Rich repeat zf-HC5HC2H_2 PF13832.1 AET37936.1 - 7.1e-13 48.5 1.4 7.1e-13 48.5 1.0 5.3 5 0 0 5 5 5 3 PHD-zinc-finger like domain BAH PF01426.13 AET37936.1 - 4.5e-12 45.7 0.1 1.1e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 AET37936.1 - 1.6e-10 40.4 57.4 1.4e-07 31.0 6.2 7.0 6 1 1 7 7 7 3 PHD-finger zf-HC5HC2H PF13771.1 AET37936.1 - 2.8e-09 36.9 2.3 2.8e-09 36.9 1.6 5.5 6 0 0 6 6 6 2 PHD-like zinc-binding domain PHD_2 PF13831.1 AET37936.1 - 4.3e-05 22.7 25.9 0.00029 20.0 2.3 5.5 5 1 0 5 5 5 3 PHD-finger Myb_DNA-binding PF00249.26 AET37936.1 - 0.021 14.8 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain C1_1 PF00130.17 AET37936.1 - 0.8 9.4 48.7 0.064 12.9 3.5 6.1 6 0 0 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) mRNA_cap_enzyme PF01331.14 AET37937.1 - 1.1e-56 191.6 0.1 1.6e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 AET37937.1 - 4.5e-21 75.1 0.3 2.3e-20 72.8 0.2 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 AET37937.1 - 1.8e-07 30.7 0.0 1.6e-06 27.6 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF845 PF05820.6 AET37937.1 - 0.077 12.7 0.0 0.25 11.0 0.0 1.8 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF845) DAP3 PF10236.4 AET37938.1 - 8e-78 261.4 0.1 1.3e-77 260.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 AET37938.1 - 0.00086 18.7 0.1 0.0023 17.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 AET37938.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 AET37938.1 - 0.0024 17.5 0.1 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 NTPase Arch_ATPase PF01637.13 AET37938.1 - 0.0024 17.5 0.8 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_19 PF13245.1 AET37938.1 - 0.0045 16.7 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF258 PF03193.11 AET37938.1 - 0.0047 16.1 0.2 0.033 13.3 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AET37938.1 - 0.0073 16.4 0.0 0.022 14.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AET37938.1 - 0.01 15.2 0.3 0.058 12.8 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 AET37938.1 - 0.012 15.8 0.1 0.036 14.2 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.1 AET37938.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AET37938.1 - 0.015 16.1 0.1 0.04 14.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain ArgK PF03308.11 AET37938.1 - 0.016 14.0 0.0 0.033 12.9 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 AET37938.1 - 0.018 15.3 0.2 0.045 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AET37938.1 - 0.02 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AET37938.1 - 0.021 14.6 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RE_LlaMI PF09562.5 AET37938.1 - 0.022 13.9 0.2 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 LlaMI restriction endonuclease MMR_HSR1 PF01926.18 AET37938.1 - 0.024 14.5 0.1 0.059 13.3 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 AET37938.1 - 0.038 14.4 0.0 0.081 13.4 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein NACHT PF05729.7 AET37938.1 - 0.069 12.8 0.5 0.21 11.2 0.1 2.0 2 0 0 2 2 1 0 NACHT domain T2SE PF00437.15 AET37938.1 - 0.073 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 AET37938.1 - 0.08 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 AET37938.1 - 0.083 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 AET37938.1 - 2.9 8.1 8.5 11 6.2 5.0 2.6 1 1 1 2 2 2 0 AAA domain PseudoU_synth_1 PF01416.15 AET37939.1 - 2.7e-19 69.5 0.0 4.7e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2084 PF09857.4 AET37939.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2084) UPF0113 PF03657.8 AET37940.1 - 1e-09 38.2 0.0 1.4e-09 37.8 0.0 1.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 AET37940.1 - 0.037 13.7 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 PUA domain Nol1_Nop2_Fmu_2 PF13636.1 AET37940.1 - 0.043 13.8 0.0 0.095 12.7 0.0 1.7 1 1 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis SRP72 PF08492.7 AET37941.1 - 1.6e-11 44.4 2.3 1.6e-11 44.4 1.6 2.8 3 0 0 3 3 2 1 SRP72 RNA-binding domain TPR_2 PF07719.12 AET37941.1 - 4.9e-06 26.0 4.5 0.41 10.6 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 AET37941.1 - 2.2e-05 24.6 0.1 9.2 7.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AET37941.1 - 7e-05 22.6 2.7 0.075 12.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AET37941.1 - 0.00059 20.1 2.8 21 5.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 AET37941.1 - 0.0011 18.1 2.5 0.13 11.3 0.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AET37941.1 - 0.0012 18.9 0.8 0.032 14.3 0.1 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 AET37941.1 - 0.0032 17.0 2.3 6.5 6.5 0.0 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 AET37941.1 - 0.0042 16.7 1.0 9.6 6.2 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 AET37941.1 - 0.15 12.0 0.0 6.4 6.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 AET37941.1 - 0.19 11.5 6.5 3 7.8 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DEAD PF00270.24 AET37942.1 - 5.1e-30 104.1 0.3 1.1e-29 103.0 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET37942.1 - 2e-14 53.2 0.0 8.5e-14 51.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET37942.1 - 4.2e-07 29.9 0.0 1.3e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AET37942.1 - 0.00021 20.2 1.7 0.00024 19.9 0.4 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 AET37942.1 - 0.055 13.6 0.4 0.73 9.9 0.1 2.9 2 1 0 2 2 2 0 AAA domain RNA_pol_Rpb1_7 PF04990.7 AET37942.1 - 0.056 13.1 0.5 0.47 10.1 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 Pkinase PF00069.20 AET37943.1 - 6.8e-70 235.1 0.1 9.7e-70 234.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37943.1 - 3.3e-44 150.9 0.0 4.5e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET37943.1 - 1.1e-05 24.6 0.0 2.2e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AET37943.1 - 0.024 13.9 0.1 0.049 12.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 AET37943.1 - 0.044 12.8 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.23 AET37944.1 - 2.5e-09 37.6 0.0 6.6e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 SET domain Wyosine_form PF08608.7 AET37945.1 - 3.7e-22 78.1 0.0 1.6e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.16 AET37945.1 - 1.9e-21 76.9 0.0 5.2e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 AET37945.1 - 2.1e-11 43.9 0.0 4.7e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Guanylate_kin PF00625.16 AET37945.1 - 0.0099 15.3 0.3 0.27 10.6 0.0 2.2 2 0 0 2 2 2 1 Guanylate kinase AAA_23 PF13476.1 AET37945.1 - 0.066 13.5 0.1 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glycos_transf_1 PF00534.15 AET37946.1 - 2.2e-31 108.5 0.0 1.9e-30 105.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AET37946.1 - 4.9e-06 26.3 0.0 1.6e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 AET37946.1 - 0.0014 18.7 0.0 0.039 14.1 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AET37946.1 - 0.0015 18.6 0.0 0.0036 17.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Peptidase_S9 PF00326.16 AET37946.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family SCA7 PF08313.7 AET37947.1 - 4.2e-33 112.7 2.3 4.2e-33 112.7 1.6 2.5 3 0 0 3 3 3 1 SCA7, zinc-binding domain Sgf11 PF08209.6 AET37947.1 - 0.019 14.2 0.5 0.041 13.2 0.4 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) GDPD PF03009.12 AET37948.1 - 1.3e-30 106.7 0.0 2.9e-30 105.6 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 AET37948.1 - 9.7e-06 25.6 0.2 0.00012 22.1 0.0 2.8 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family PA14_2 PF10528.4 AET37949.1 - 7.5e-15 54.8 0.6 1.7e-14 53.7 0.4 1.6 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 AET37949.1 - 3.7e-09 36.3 0.1 6.4e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Flocculin PF00624.13 AET37949.1 - 1.5e-05 24.6 13.4 5.2e-05 22.9 9.3 2.0 1 0 0 1 1 1 1 Flocculin repeat C1q PF00386.16 AET37949.1 - 0.061 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 C1q domain PA14_2 PF10528.4 AET37950.1 - 7.3e-15 54.9 0.6 1.3e-14 54.1 0.4 1.4 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 AET37950.1 - 3.3e-09 36.5 0.1 4.9e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 PA14 domain C1q PF00386.16 AET37950.1 - 0.066 13.2 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 C1q domain Pkinase PF00069.20 AET37951.1 - 7.9e-41 139.9 0.0 1.6e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37951.1 - 1.3e-14 53.9 0.0 3.2e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AET37951.1 - 0.00033 20.4 0.1 0.086 12.5 0.0 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AET37951.1 - 0.033 12.9 0.1 0.066 11.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 AET37952.1 - 8.2e-69 231.6 0.0 9.7e-69 231.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET37952.1 - 1.5e-39 135.6 0.0 1.9e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET37952.1 - 1.7e-05 23.9 0.0 2.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 AET37952.1 - 0.016 14.5 0.1 0.036 13.3 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Ribosomal_L12 PF00542.14 AET37953.1 - 9.9e-21 73.5 9.4 9.8e-20 70.3 5.3 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 AET37953.1 - 0.0015 18.9 2.1 0.0015 18.9 1.4 2.3 1 1 2 3 3 3 1 60s Acidic ribosomal protein DUF2267 PF10025.4 AET37953.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) RNA_POL_M_15KD PF02150.11 AET37954.1 - 5.9e-15 54.6 3.4 5.9e-15 54.6 2.4 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 AET37954.1 - 1e-14 53.8 15.5 1.4e-14 53.4 1.4 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 AET37954.1 - 0.00023 21.3 3.0 0.0034 17.6 0.2 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar DUF2387 PF09526.5 AET37954.1 - 0.00099 18.9 2.9 0.052 13.4 0.2 2.3 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) Cytochrome_C7 PF14522.1 AET37954.1 - 0.038 13.6 2.8 0.19 11.3 0.2 2.3 2 0 0 2 2 2 0 Cytochrome c7 DZR PF12773.2 AET37954.1 - 0.04 13.7 9.1 0.13 12.0 0.6 2.6 2 1 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 AET37954.1 - 0.054 13.2 6.1 0.063 13.0 0.3 2.5 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Rubredoxin PF00301.15 AET37954.1 - 0.061 13.2 3.5 55 3.7 0.0 4.0 4 0 0 4 4 4 0 Rubredoxin C1_4 PF07975.7 AET37954.1 - 0.085 12.8 11.7 0.44 10.5 0.8 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 AET37954.1 - 0.23 11.3 12.1 4.5 7.1 2.8 3.1 2 1 1 3 3 3 0 Transposase zinc-ribbon domain GFA PF04828.9 AET37954.1 - 0.23 11.4 5.2 3.4 7.6 0.2 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 AET37954.1 - 0.38 10.6 6.1 7.7 6.4 0.1 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cytochrom_c3_2 PF14537.1 AET37954.1 - 0.45 10.9 4.5 0.37 11.1 0.5 2.1 2 0 0 2 2 2 0 Cytochrome c3 IBR PF01485.16 AET37954.1 - 0.62 9.9 7.2 1.7 8.5 0.4 2.6 2 1 0 2 2 2 0 IBR domain zf-UBP PF02148.14 AET37954.1 - 0.63 10.1 5.9 0.55 10.3 0.3 2.3 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-CHY PF05495.7 AET37954.1 - 1.2 9.3 9.0 0.69 10.1 0.6 2.4 2 1 1 3 3 3 0 CHY zinc finger HypA PF01155.14 AET37954.1 - 1.5 8.5 8.1 8 6.1 3.2 2.9 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 AET37954.1 - 3.5 7.6 13.5 4.3 7.3 0.1 3.8 3 1 1 4 4 4 0 Zinc ribbon domain Cytochrom_NNT PF03264.9 AET37954.1 - 5.2 6.4 8.9 0.092 12.1 0.7 2.1 2 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region AFT PF08731.6 AET37955.1 - 6.3e-47 158.3 1.1 3.9e-45 152.6 0.0 2.6 2 0 0 2 2 2 2 Transcription factor AFT DBD_Tnp_Mut PF03108.10 AET37955.1 - 0.00035 20.0 3.8 0.13 11.8 0.0 2.9 3 0 0 3 3 3 2 MuDR family transposase PQQ_3 PF13570.1 AET37956.1 - 0.0043 17.2 2.5 22 5.4 0.0 4.8 5 0 0 5 5 5 1 PQQ-like domain DUF4613 PF15390.1 AET37956.1 - 0.056 11.6 0.0 0.08 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) eIF2A PF08662.6 AET37956.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A CNH PF00780.17 AET37956.1 - 0.12 11.7 0.0 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 CNH domain Rrn6 PF10214.4 AET37956.1 - 0.2 9.6 0.1 0.29 9.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor HSF_DNA-bind PF00447.12 AET37957.1 - 5.3e-36 122.9 1.5 1.3e-35 121.6 1.0 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4476 PF14771.1 AET37957.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) DUF1771 PF08590.5 AET37959.1 - 6.7e-22 77.2 13.3 1.1e-21 76.5 9.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 AET37959.1 - 1.7e-17 63.3 0.2 8.1e-17 61.1 0.0 2.1 2 1 0 2 2 2 1 Smr domain Caudo_TAP PF02413.12 AET37959.1 - 0.05 13.7 4.7 0.09 12.9 3.3 1.4 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Dispanin PF04505.7 AET37959.1 - 0.093 12.2 0.2 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF4337 PF14235.1 AET37959.1 - 0.2 11.5 9.5 0.3 10.9 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Seryl_tRNA_N PF02403.17 AET37959.1 - 0.35 10.8 6.1 0.62 10.0 4.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 AET37959.1 - 2.4 7.0 5.6 3.2 6.6 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L30 PF00327.15 AET37960.1 - 5.1e-20 70.8 1.2 1.1e-19 69.7 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 AET37960.1 - 2.7e-19 68.9 16.1 4.9e-19 68.1 11.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain CDK5_activator PF03261.10 AET37960.1 - 0.086 12.1 0.6 0.12 11.7 0.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PV-1 PF06637.6 AET37960.1 - 7.3 5.0 9.4 10 4.5 6.5 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF4407 PF14362.1 AET37960.1 - 9.5 5.0 8.7 13 4.6 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AA_permease_2 PF13520.1 AET37961.1 - 8.7e-50 169.4 44.4 1.1e-49 169.2 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AET37961.1 - 8.1e-21 73.9 41.2 1.2e-20 73.3 28.6 1.3 1 1 0 1 1 1 1 Amino acid permease DEAD PF00270.24 AET37962.1 - 3.9e-52 176.1 0.1 3.2e-50 169.9 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET37962.1 - 1.6e-29 101.5 0.1 1.1e-28 98.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HTH_7 PF02796.10 AET37962.1 - 0.03 14.1 0.0 0.082 12.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase CMS1 PF14617.1 AET37962.1 - 0.059 12.4 0.1 0.059 12.4 0.0 3.2 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Tom37_C PF11801.3 AET37962.1 - 1.3 8.8 13.1 2.9 7.7 9.0 1.6 1 0 0 1 1 1 0 Tom37 C-terminal domain Rtf2 PF04641.7 AET37962.1 - 2.5 7.2 28.3 6.1 5.9 19.6 1.7 1 0 0 1 1 1 0 Rtf2 RING-finger MIP-T3 PF10243.4 AET37962.1 - 5.4 5.3 40.0 8.2 4.7 27.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 AET37962.1 - 8.1 5.7 30.2 15 4.8 20.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FA_desaturase PF00487.19 AET37963.1 - 1.5e-39 135.9 21.1 2e-39 135.5 14.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 AET37963.1 - 3.8e-13 49.0 0.0 1.3e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF3821 PF12863.2 AET37963.1 - 0.017 14.7 0.5 5.7 6.5 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3821) TLD PF07534.11 AET37964.1 - 7.3e-28 97.3 0.0 1.2e-12 47.9 0.1 2.1 2 0 0 2 2 2 2 TLD KxDL PF10241.4 AET37965.1 - 5.3e-07 29.4 0.1 7.6e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Flu_NS2 PF00601.14 AET37965.1 - 0.085 13.0 0.5 0.17 12.1 0.3 1.5 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) Methyltrn_RNA_2 PF04013.7 AET37965.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase Adaptin_N PF01602.15 AET37966.1 - 1.8e-110 369.7 18.1 2.5e-110 369.2 12.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AET37966.1 - 2.5e-06 27.6 0.1 0.24 11.6 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 AET37966.1 - 8.4e-06 25.4 0.7 9.3 6.6 0.0 5.9 5 1 1 6 6 6 2 HEAT repeat Vac14_Fab1_bd PF12755.2 AET37966.1 - 0.11 12.9 0.2 0.11 12.9 0.2 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 AET37966.1 - 0.11 12.3 3.0 0.73 9.7 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Rad9 PF04139.8 AET37967.1 - 7.2e-10 38.4 0.2 0.00018 20.7 0.0 2.3 2 1 0 2 2 2 2 Rad9 Hus1 PF04005.7 AET37967.1 - 0.055 12.4 0.9 0.23 10.3 0.2 2.2 2 0 0 2 2 2 0 Hus1-like protein MPC PF03650.8 AET37968.1 - 2.9e-39 133.6 0.1 3.2e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) NUFIP1 PF10453.4 AET37969.1 - 1.6e-14 53.1 4.3 3.5e-14 52.0 3.0 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) FHA PF00498.21 AET37971.1 - 1.2e-05 25.2 0.1 3.7e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain DUF3782 PF12644.2 AET37971.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) DUF544 PF04424.8 AET37972.1 - 9.5e-24 83.5 0.0 1.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) RRM_1 PF00076.17 AET37973.1 - 1.7e-09 37.1 0.4 3.6e-09 36.1 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET37973.1 - 4.7e-06 26.4 0.1 9.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET37973.1 - 0.0028 17.4 0.2 0.0063 16.3 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MBOAT PF03062.14 AET37975.1 - 3.1e-58 197.4 22.2 3.1e-58 197.4 15.4 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family SNase PF00565.12 AET37976.1 - 5.7e-20 71.5 0.0 1.1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue UQ_con PF00179.21 AET37977.1 - 2.3e-18 66.0 0.0 2.5e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AET37977.1 - 0.016 15.1 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 AET37977.1 - 0.026 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 UEV domain NAD_kinase PF01513.16 AET37978.1 - 1.2e-50 171.9 0.0 1.5e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF1116 PF06545.6 AET37978.1 - 0.045 12.8 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) DAGK_cat PF00781.19 AET37978.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MF_alpha PF04648.7 AET37979.1 - 5.7e-17 60.7 25.8 0.00094 19.2 0.9 4.3 4 0 0 4 4 4 4 Yeast mating factor alpha hormone MF_alpha_N PF05436.6 AET37979.1 - 7.1e-15 54.4 0.4 9e-15 54.1 0.3 1.1 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus Cu_amine_oxidN2 PF02727.11 AET37979.1 - 0.013 15.5 4.1 20 5.3 0.1 3.3 1 1 2 3 3 3 0 Copper amine oxidase, N2 domain DUF287 PF03384.9 AET37979.1 - 0.14 12.3 5.2 33 4.7 0.0 3.9 1 1 3 4 4 4 0 Drosophila protein of unknown function, DUF287 zf-H2C2 PF09337.5 AET37979.1 - 4.4 6.8 8.2 71 2.9 0.1 4.0 4 0 0 4 4 4 0 His(2)-Cys(2) zinc finger Tox-GHH PF15636.1 AET37979.1 - 6.4 6.4 9.2 49 3.6 0.2 3.4 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin RRM_6 PF14259.1 AET37980.1 - 3.3e-29 100.6 1.1 6.2e-07 29.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET37980.1 - 1.3e-28 98.3 2.4 5.3e-07 29.1 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET37980.1 - 7e-22 77.0 3.2 3.4e-06 26.8 0.1 4.6 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AET37980.1 - 0.0066 16.2 0.1 0.62 9.9 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif Pox_polyA_pol_C PF12629.2 AET37980.1 - 0.052 13.2 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase C-terminal domain Nup35_RRM_2 PF14605.1 AET37980.1 - 0.065 13.0 0.1 0.76 9.5 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif NYD-SP28 PF14772.1 AET37981.1 - 0.1 12.6 0.6 0.17 11.9 0.4 1.3 1 0 0 1 1 1 0 Sperm tail ParA PF10609.4 AET37982.1 - 7.9e-36 121.8 0.1 1.9e-35 120.5 0.0 1.6 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 AET37982.1 - 2.9e-16 59.4 0.0 4.1e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 AET37982.1 - 1.6e-05 24.1 0.0 2.6e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 AET37982.1 - 3e-05 24.0 0.0 0.00012 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 AET37982.1 - 0.00013 21.0 1.0 0.0027 16.8 0.0 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase DUF258 PF03193.11 AET37982.1 - 0.0024 17.0 0.1 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 AET37982.1 - 0.025 14.0 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 AET37982.1 - 0.026 13.2 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Fer4_NifH PF00142.13 AET37982.1 - 0.11 11.6 0.0 1.1 8.3 0.0 2.4 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_29 PF13555.1 AET37982.1 - 0.13 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nup96 PF12110.3 AET37983.1 - 2.2e-59 200.9 0.1 3.4e-59 200.3 0.1 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 AET37983.1 - 1.9e-47 160.6 0.0 3.7e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 AET37983.1 - 2.3e-09 37.4 83.0 4.5e-09 36.5 25.1 4.5 1 1 2 3 3 3 2 Nucleoporin FG repeat region Spc7 PF08317.6 AET37984.1 - 1.3e-82 277.1 17.2 2.6e-82 276.1 11.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 AET37984.1 - 0.041 13.5 1.2 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 Spc7_C2 ICEA PF05315.6 AET37984.1 - 0.058 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 ICEA Protein Ribosomal_L36 PF00444.13 AET37985.1 - 1.1e-20 73.2 10.7 1.8e-20 72.6 7.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 AET37985.1 - 0.0013 18.0 2.1 0.0019 17.4 1.5 1.2 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family WD40 PF00400.27 AET37986.1 - 2e-27 93.9 19.5 1.2e-08 34.5 0.0 10.5 12 0 0 12 12 12 5 WD domain, G-beta repeat Nup160 PF11715.3 AET37986.1 - 0.00051 18.3 8.3 0.064 11.3 0.2 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Str_synth PF03088.11 AET37986.1 - 0.0074 16.3 0.0 0.12 12.4 0.0 2.9 3 0 0 3 3 3 1 Strictosidine synthase YmzC PF14157.1 AET37986.1 - 0.039 13.7 0.0 8.2 6.3 0.0 3.0 2 0 0 2 2 2 0 YmzC-like protein UCH_1 PF13423.1 AET37987.1 - 5.7e-47 160.5 2.5 1e-46 159.7 1.7 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 AET37987.1 - 7.5e-27 94.6 0.0 2.2e-26 93.0 0.0 1.9 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 AET37987.1 - 2.2e-05 23.6 5.0 0.00034 19.8 2.8 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TCO89 PF10452.4 AET37988.1 - 1.4e-155 519.6 43.2 8.2e-113 378.4 12.8 2.5 1 1 1 2 2 2 2 TORC1 subunit TCO89 FNIP_C PF14638.1 AET37988.1 - 0.02 14.2 0.1 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Sec1 PF00995.18 AET37989.1 - 8.3e-133 443.9 14.0 9.4e-133 443.8 9.7 1.0 1 0 0 1 1 1 1 Sec1 family MutS_III PF05192.13 AET37989.1 - 0.071 12.8 1.3 0.22 11.2 0.8 1.9 1 1 0 1 1 1 0 MutS domain III PHD PF00628.24 AET37990.1 - 3.5e-10 39.4 6.8 6.8e-10 38.4 4.7 1.5 1 0 0 1 1 1 1 PHD-finger Daxx PF03344.10 AET37990.1 - 0.97 7.8 58.8 0.21 10.0 21.6 2.0 2 0 0 2 2 2 0 Daxx Family PHD_2 PF13831.1 AET37990.1 - 1.2 8.5 6.4 2.2 7.6 4.4 1.5 1 0 0 1 1 1 0 PHD-finger Metallophos PF00149.23 AET37991.1 - 2.3e-38 131.5 0.0 3.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.17 AET37992.1 - 2.6e-15 55.7 0.0 4.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET37992.1 - 1.1e-12 47.7 0.0 1.8e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET37992.1 - 1e-09 38.0 0.0 1.7e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 AET37992.1 - 3.1e-05 23.1 0.4 3.1e-05 23.1 0.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter BAF1_ABF1 PF04684.8 AET37992.1 - 0.12 11.1 17.8 0.15 10.8 12.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 AET37992.1 - 0.61 9.4 15.4 0.9 8.8 10.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Innate_immun PF12782.2 AET37992.1 - 1.6 7.8 16.3 2.3 7.3 11.3 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Macoilin PF09726.4 AET37992.1 - 4.6 5.3 7.2 5.9 5.0 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Homeobox_KN PF05920.6 AET37993.1 - 1.1e-17 63.4 0.6 3.1e-17 61.9 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 AET37993.1 - 2.8e-06 26.8 0.3 7.3e-06 25.5 0.2 1.7 1 0 0 1 1 1 1 Homeobox domain Arrestin_N PF00339.24 AET37994.1 - 0.0046 16.7 0.1 0.064 13.0 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain GCV_T PF01571.16 AET37994.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DAHP_synth_1 PF00793.15 AET37995.1 - 3e-99 331.1 0.0 3.8e-99 330.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family His_biosynth PF00977.16 AET37996.1 - 8e-47 159.4 0.3 3.4e-46 157.3 0.2 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 AET37996.1 - 2.1e-28 99.0 0.0 3.2e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 AET37996.1 - 4.3e-08 32.8 0.0 9.7e-08 31.7 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 AET37996.1 - 2.9e-07 30.2 0.0 6.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Dus PF01207.12 AET37996.1 - 0.0054 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) UPRTase PF14681.1 AET37996.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ThiG PF05690.9 AET37996.1 - 0.14 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG RCC1 PF00415.13 AET37997.1 - 1e-62 208.1 0.0 7.5e-15 54.8 0.0 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AET37997.1 - 1.2e-39 133.0 16.3 1.9e-09 36.9 0.0 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 AET37997.1 - 0.041 13.3 0.0 3.6 7.1 0.0 3.4 4 0 0 4 4 4 0 Putative carbohydrate binding domain SUKH-3 PF14433.1 AET37997.1 - 0.07 12.9 2.4 19 5.0 0.0 4.2 6 0 0 6 6 6 0 SUKH-3 immunity protein PD40 PF07676.7 AET37997.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Bystin PF05291.6 AET37998.1 - 2e-123 411.1 0.0 2.8e-123 410.6 0.0 1.2 1 0 0 1 1 1 1 Bystin DnaB_2 PF07261.6 AET37998.1 - 0.022 14.3 0.0 0.096 12.3 0.0 2.0 2 0 0 2 2 2 0 Replication initiation and membrane attachment Use1 PF09753.4 AET37999.1 - 6.9e-09 35.5 2.9 1.6e-08 34.3 2.0 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 SAC3_GANP PF03399.11 AET37999.1 - 0.0055 16.2 0.2 0.01 15.4 0.2 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Tox-REase-9 PF15650.1 AET37999.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 SMAP PF15477.1 AET37999.1 - 0.075 13.3 0.5 0.2 11.9 0.3 1.7 1 0 0 1 1 1 0 Small acidic protein family Rho_GDI PF02115.12 AET37999.1 - 0.17 11.2 5.9 0.098 12.0 2.7 1.6 1 1 0 1 1 1 0 RHO protein GDP dissociation inhibitor DUF2939 PF11159.3 AET37999.1 - 1.7 8.8 4.6 1.9 8.7 0.7 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2939) MMR_HSR1 PF01926.18 AET38000.1 - 2.5e-17 62.8 0.2 8.6e-15 54.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AET38000.1 - 2.4e-08 33.3 0.2 6.9e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 AET38000.1 - 0.0004 19.5 0.0 0.00074 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 AET38000.1 - 0.003 16.7 0.1 0.0074 15.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 AET38000.1 - 0.028 14.2 0.4 0.028 14.2 0.3 3.3 3 1 0 3 3 3 0 Dynamin family Miro PF08477.8 AET38000.1 - 0.13 12.7 0.1 0.13 12.7 0.0 2.5 3 0 0 3 3 3 0 Miro-like protein PI3K_1B_p101 PF10486.4 AET38000.1 - 0.22 9.0 1.6 0.32 8.5 1.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit WD40 PF00400.27 AET38001.1 - 3e-07 30.0 5.8 0.27 11.1 0.2 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ PF01011.16 AET38001.1 - 0.00057 19.2 0.1 1.6 8.3 0.0 3.3 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.1 AET38001.1 - 0.036 13.5 0.0 0.34 10.3 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain SNF2_N PF00176.18 AET38002.1 - 7.6e-79 264.6 0.3 1.3e-78 263.8 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 AET38002.1 - 1.4e-41 140.8 2.1 6.5e-41 138.7 1.5 2.3 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 AET38002.1 - 3.2e-31 108.0 0.6 3.2e-31 108.0 0.4 4.7 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 AET38002.1 - 7.5e-16 57.7 0.0 2.3e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AET38002.1 - 6.6e-12 44.8 0.0 1.7e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 AET38002.1 - 2.8e-09 37.0 0.0 4.1e-08 33.2 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AET38002.1 - 6.3e-07 29.0 0.0 1.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 AET38002.1 - 0.0021 17.5 0.2 0.005 16.2 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.1 AET38002.1 - 0.027 14.3 0.9 0.11 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain GSHPx PF00255.14 AET38003.1 - 8.2e-46 153.8 0.4 1.1e-45 153.4 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 AET38003.1 - 2.7e-07 30.3 0.1 1.2e-06 28.2 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AET38003.1 - 1.3e-05 24.8 0.0 4.7e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 AET38003.1 - 0.037 13.6 0.1 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 SCO1/SenC DUF4174 PF13778.1 AET38003.1 - 0.084 12.9 0.0 0.17 12.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) WD40 PF00400.27 AET38004.1 - 7.2e-35 117.6 19.2 3.2e-09 36.3 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat YmzC PF14157.1 AET38004.1 - 0.0086 15.8 0.0 0.38 10.6 0.0 2.7 2 0 0 2 2 2 1 YmzC-like protein Glycos_transf_4 PF00953.16 AET38005.1 - 1.5e-31 109.3 10.7 1.5e-31 109.3 7.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 4 PgaD PF13994.1 AET38005.1 - 1.3 8.5 4.3 5.2 6.5 0.0 3.0 3 0 0 3 3 3 0 PgaD-like protein HD_3 PF13023.1 AET38006.1 - 6.2e-34 117.1 0.1 8e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 AET38006.1 - 2e-06 27.8 0.2 0.00011 22.2 0.2 2.4 1 1 0 1 1 1 1 HD domain Ribosomal_L18e PF00828.14 AET38007.1 - 2.3e-35 121.7 0.2 3.3e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Sugar_tr PF00083.19 AET38008.1 - 1.6e-96 323.6 21.4 2e-96 323.3 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET38008.1 - 1.6e-27 96.1 58.0 1.8e-26 92.6 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AET38008.1 - 3.6e-07 28.7 1.7 3.6e-07 28.7 1.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 AET38009.1 - 7.6e-11 41.7 6.1 7.6e-11 41.7 4.2 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_bind PF01588.15 AET38010.1 - 9.5e-29 99.0 0.4 2.7e-28 97.6 0.0 1.9 2 0 0 2 2 2 1 Putative tRNA binding domain Stn1 PF10451.4 AET38010.1 - 0.2 10.4 0.6 1.2 7.8 0.0 2.2 3 0 0 3 3 3 0 Telomere regulation protein Stn1 PAS PF00989.19 AET38011.1 - 2.7e-15 56.1 0.0 1.1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 AET38011.1 - 9.9e-07 28.5 10.9 1.9e-06 27.6 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 AET38011.1 - 0.071 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 PAS domain EF-hand_7 PF13499.1 AET38012.1 - 3.2e-12 46.3 0.1 9.4e-08 32.0 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AET38012.1 - 1e-09 37.4 0.9 0.00062 19.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.1 AET38012.1 - 4.6e-08 32.8 0.0 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 AET38012.1 - 2.6e-06 26.3 5.8 0.00063 18.8 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 AET38012.1 - 9.6e-06 25.1 1.8 4.2e-05 23.0 0.3 2.5 2 1 1 3 3 3 1 EF-hand domain pair DUF3407 PF11887.3 AET38014.1 - 0.056 12.7 0.1 0.062 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) vMSA PF00695.14 AET38014.1 - 0.77 8.8 2.6 0.87 8.7 1.8 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF913 PF06025.7 AET38014.1 - 1.7 7.3 5.8 2 7.0 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ATP-synt_DE PF00401.15 AET38014.1 - 3.6 7.5 8.8 7.2 6.5 6.1 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DEAD PF00270.24 AET38015.1 - 1.6e-41 141.6 0.0 3.1e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET38015.1 - 5.9e-18 64.5 0.0 1.6e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4319 PF14203.1 AET38015.1 - 0.025 14.1 1.6 0.056 12.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) Fis1_TPR_N PF14852.1 AET38015.1 - 0.31 10.3 1.7 1.8 7.9 0.0 2.7 3 0 0 3 3 3 0 Fis1 N-terminal tetratricopeptide repeat Pox_MCEL PF03291.11 AET38016.1 - 1.6e-96 323.1 0.2 2.1e-96 322.6 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 AET38016.1 - 1.5e-09 37.7 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET38016.1 - 5e-09 36.7 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AET38016.1 - 2e-08 34.6 0.0 5.3e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AET38016.1 - 1.5e-07 31.7 0.2 5.5e-07 29.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET38016.1 - 9.6e-07 28.5 0.1 2.5e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET38016.1 - 2.7e-06 27.6 0.1 5.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AET38016.1 - 0.0013 17.7 0.0 0.0037 16.2 0.0 1.7 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 AET38016.1 - 0.0024 16.9 0.0 0.0064 15.5 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 AET38016.1 - 0.0048 16.0 0.9 0.021 13.9 0.0 2.2 2 1 1 3 3 3 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 AET38016.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AET38016.1 - 0.018 14.5 0.1 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Hom_end_hint PF05203.11 AET38016.1 - 0.04 13.6 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint CagY_I PF14585.1 AET38016.1 - 0.1 12.5 1.1 0.45 10.4 1.1 1.8 2 0 0 2 2 2 0 CagY type 1 repeat AA_permease PF00324.16 AET38017.1 - 3.5e-44 150.9 39.9 3.5e-44 150.9 27.6 1.7 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.1 AET38017.1 - 3.1e-11 42.4 48.2 4.4e-11 41.9 33.4 1.2 1 0 0 1 1 1 1 Amino acid permease CUE PF02845.11 AET38018.1 - 4.7e-09 35.5 0.1 1.2e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 CUE domain EnY2 PF10163.4 AET38018.1 - 0.35 10.8 2.9 0.35 10.8 0.4 2.4 3 1 0 3 3 3 0 Transcription factor e(y)2 PRP1_N PF06424.7 AET38019.1 - 0.1 12.9 2.5 0.22 11.8 1.8 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal WD40 PF00400.27 AET38020.1 - 2.3e-14 52.6 15.3 8.9e-05 22.2 0.2 6.4 7 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 AET38020.1 - 9.3e-05 22.2 0.5 0.028 14.1 0.1 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.2 AET38020.1 - 0.0087 15.3 0.2 0.018 14.2 0.1 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity mRNA_cap_C PF03919.10 AET38020.1 - 0.12 12.6 0.2 0.61 10.4 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain DASH_Dad3 PF08656.5 AET38021.1 - 2.4e-26 91.1 1.3 2.6e-26 91.1 0.9 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Metal_resist PF13801.1 AET38021.1 - 0.031 14.2 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Heavy-metal resistance bPH_6 PF10756.4 AET38021.1 - 0.1 12.4 0.1 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain FlxA PF14282.1 AET38021.1 - 0.13 12.2 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF1546 PF07571.8 AET38022.1 - 1.2e-32 111.8 0.0 3e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 AET38022.1 - 3.4e-28 97.3 0.3 7.2e-28 96.3 0.2 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 AET38022.1 - 0.0002 21.3 0.3 0.0043 17.1 0.1 2.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 AET38022.1 - 0.013 15.2 0.1 0.042 13.6 0.1 1.9 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CLASP_N PF12348.3 AET38022.1 - 0.038 13.3 2.5 0.18 11.1 0.4 2.4 2 1 0 3 3 3 0 CLASP N terminal TAF4 PF05236.9 AET38022.1 - 0.061 12.5 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CBFD_NFYB_HMF PF00808.18 AET38022.1 - 0.087 12.8 0.5 0.33 11.0 0.1 2.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 AET38022.1 - 0.28 11.3 4.9 1.4 9.1 0.1 3.2 4 0 0 4 4 4 0 Kinetochore component CENP-S HsbA PF12296.3 AET38022.1 - 0.32 10.8 6.2 9.8 6.0 0.8 3.4 2 1 1 3 3 3 0 Hydrophobic surface binding protein A SLD3 PF08639.5 AET38023.1 - 6.1e-74 249.4 21.0 9.5e-74 248.8 14.6 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 KH_1 PF00013.24 AET38024.1 - 1.6e-33 114.1 9.7 3.3e-11 42.6 2.7 4.0 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 AET38024.1 - 3.4e-26 90.3 12.0 3.6e-08 32.8 2.6 4.5 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 AET38024.1 - 1.5e-10 40.4 0.7 0.077 12.5 0.0 3.7 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 AET38024.1 - 0.0042 16.6 2.7 1.6 8.3 0.0 3.3 3 1 0 3 3 3 2 KH domain KH_5 PF13184.1 AET38024.1 - 0.3 10.9 4.5 4.5 7.1 0.1 3.6 3 1 0 3 3 3 0 NusA-like KH domain BCNT PF07572.7 AET38025.1 - 1.7e-26 91.9 0.1 5.1e-26 90.4 0.1 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development CBS PF00571.23 AET38026.1 - 5.3e-29 99.7 2.8 4.1e-13 48.8 0.1 4.2 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.6 AET38026.1 - 0.37 10.6 2.3 3 7.8 0.1 3.0 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain WD40 PF00400.27 AET38027.1 - 1.9e-22 78.2 13.3 2.1e-08 33.7 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF2153 PF09921.4 AET38028.1 - 0.1 12.2 0.7 0.42 10.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) GAF_2 PF13185.1 AET38029.1 - 1.3e-08 35.5 0.0 1.8e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 AET38029.1 - 0.0058 16.7 0.0 0.009 16.1 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 AET38029.1 - 0.0059 16.7 0.0 0.007 16.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain BOP1NT PF08145.7 AET38030.1 - 9.3e-104 346.7 7.4 1.6e-103 345.9 5.1 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 AET38030.1 - 2.3e-30 103.3 4.9 1.5e-12 46.8 0.1 6.7 7 1 0 7 7 7 4 WD domain, G-beta repeat Colicin_D PF11429.3 AET38030.1 - 0.057 13.5 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Colicin D DUF506 PF04720.7 AET38030.1 - 6 6.4 10.7 0.74 9.4 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF506) Swi3 PF07962.7 AET38031.1 - 3.2e-28 97.1 0.3 3.2e-28 97.1 0.2 1.5 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 Nucleoporin_FG PF13634.1 AET38033.1 - 3.5e-47 159.3 409.8 3e-10 40.3 28.8 11.9 2 2 8 10 10 10 8 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 AET38033.1 - 4.3e-41 140.0 0.0 8.1e-41 139.1 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase SRF-TF PF00319.13 AET38034.1 - 9.5e-24 82.3 0.2 1.3e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TFIIE-A_C-term PF11521.3 AET38034.1 - 0.0041 17.0 2.5 0.015 15.2 1.7 2.0 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha Metal_resist PF13801.1 AET38034.1 - 0.0081 16.1 4.4 0.02 14.8 3.1 1.7 1 0 0 1 1 1 1 Heavy-metal resistance Myc_N PF01056.13 AET38034.1 - 0.099 11.7 3.0 0.16 11.0 2.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region PWWP PF00855.12 AET38035.1 - 9.7e-19 67.3 0.5 4.7e-18 65.1 0.3 2.2 1 0 0 1 1 1 1 PWWP domain TIP41 PF04176.8 AET38035.1 - 0.034 13.3 0.4 0.088 12.0 0.3 1.6 1 0 0 1 1 1 0 TIP41-like family NDK PF00334.14 AET38036.1 - 2e-55 186.2 0.0 2.3e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Bap31 PF05529.7 AET38037.1 - 5.6e-38 130.3 11.5 1.6e-37 128.8 8.0 1.6 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like IncA PF04156.9 AET38037.1 - 0.0092 15.5 1.5 0.018 14.6 1.0 1.5 1 1 0 1 1 1 1 IncA protein SSF PF00474.12 AET38037.1 - 0.05 12.2 0.2 0.051 12.2 0.1 1.2 1 0 0 1 1 1 0 Sodium:solute symporter family Spectrin PF00435.16 AET38037.1 - 0.059 13.6 3.7 0.11 12.7 2.6 1.3 1 0 0 1 1 1 0 Spectrin repeat Vps55 PF04133.9 AET38037.1 - 0.088 12.5 0.4 7.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 55 Xan_ur_permease PF00860.15 AET38037.1 - 0.14 10.5 0.1 0.14 10.5 0.0 1.5 2 0 0 2 2 2 0 Permease family DivIC PF04977.10 AET38037.1 - 0.55 9.7 5.2 0.57 9.6 2.2 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.1 AET38037.1 - 7.7 5.3 0.0 7.7 5.3 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Aldo_ket_red PF00248.16 AET38038.1 - 6.8e-52 176.0 0.0 8.3e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PC4 PF02229.11 AET38039.1 - 4.8e-22 76.9 0.0 1.1e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) MPP6 PF10175.4 AET38039.1 - 0.016 15.5 0.1 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 M-phase phosphoprotein 6 CorA PF01544.13 AET38040.1 - 2.1e-39 135.2 5.7 2.5e-22 79.2 0.6 3.4 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein HMA PF00403.21 AET38041.1 - 1.3e-13 50.9 0.2 2.6e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 AET38041.1 - 3.9e-08 33.5 0.2 2.7e-07 30.8 0.1 2.0 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF1183 PF06682.7 AET38042.1 - 0.15 11.6 0.2 0.21 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) AA_permease PF00324.16 AET38042.1 - 0.33 9.2 1.9 2.1 6.5 0.3 2.0 2 0 0 2 2 2 0 Amino acid permease zf-C2H2 PF00096.21 AET38043.1 - 1.3e-12 47.2 13.3 7.4e-06 26.0 2.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET38043.1 - 3.6e-10 39.4 13.3 9e-05 22.5 2.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AET38043.1 - 1e-06 28.7 21.0 4.2e-06 26.7 2.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AET38043.1 - 5.1e-06 26.4 8.7 0.00087 19.3 1.4 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 AET38043.1 - 0.00016 21.3 5.6 0.037 13.7 1.0 2.8 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 AET38043.1 - 0.0017 18.1 0.7 0.0017 18.1 0.5 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AET38043.1 - 0.29 11.2 6.5 0.87 9.7 0.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 AET38043.1 - 1.4 7.3 6.6 0.89 7.9 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Pkinase PF00069.20 AET38044.1 - 6.6e-35 120.4 1.1 4.7e-30 104.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AET38044.1 - 7.2e-20 71.1 0.0 5.9e-12 45.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 AET38044.1 - 1.5e-05 24.1 0.0 0.023 13.6 0.0 2.8 2 1 1 3 3 3 2 Kinase-like APH PF01636.18 AET38044.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Rhodanese PF00581.15 AET38045.1 - 3.2e-10 40.3 0.0 8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S24 PF00717.18 AET38046.1 - 1.2e-08 34.4 0.2 3.2e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 AET38046.1 - 5.4e-05 22.7 0.0 0.00081 18.9 0.0 2.0 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 DUF4137 PF13593.1 AET38047.1 - 3e-106 355.0 20.5 3.6e-106 354.8 14.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 AET38047.1 - 9.3e-10 38.2 17.6 8.2e-09 35.1 12.1 2.1 1 1 0 1 1 1 1 Sodium Bile acid symporter family LrgB PF04172.11 AET38047.1 - 0.0055 15.8 1.1 0.0055 15.8 0.7 1.9 2 0 0 2 2 2 1 LrgB-like family Actin PF00022.14 AET38048.1 - 3.4e-21 75.1 0.0 4.1e-19 68.2 0.0 2.9 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.8 AET38048.1 - 0.01 14.4 0.0 4.5 5.7 0.0 3.0 3 0 0 3 3 3 0 MreB/Mbl protein Hydantoinase_A PF01968.13 AET38048.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase MutL PF13941.1 AET38048.1 - 0.048 11.9 0.0 0.08 11.2 0.0 1.3 1 0 0 1 1 1 0 MutL protein Histone PF00125.19 AET38049.1 - 4.2e-26 90.8 0.9 9.1e-26 89.7 0.6 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AET38049.1 - 0.0041 17.2 0.1 0.0088 16.2 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S UPF0184 PF03670.8 AET38049.1 - 0.31 11.2 2.9 0.89 9.7 2.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) FCH PF00611.18 AET38050.1 - 3.8e-18 65.4 1.3 3.8e-18 65.4 0.9 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 AET38050.1 - 6.8e-09 35.1 0.0 1.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AET38050.1 - 5.5e-08 32.1 0.0 1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AET38050.1 - 2.3e-07 30.0 0.0 5.2e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF3812 PF12757.2 AET38051.1 - 1.4e-27 96.1 4.8 1.4e-27 96.1 3.3 4.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3812) FUSC PF04632.7 AET38051.1 - 0.52 8.6 4.0 0.97 7.7 2.8 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Frag1 PF10277.4 AET38052.1 - 4.3e-70 235.5 24.2 5e-70 235.3 16.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF373 PF04123.8 AET38052.1 - 1.1 8.2 2.9 3.7 6.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Actin PF00022.14 AET38053.1 - 5.3e-23 81.0 0.0 1.9e-16 59.4 0.0 3.6 3 1 0 3 3 3 3 Actin MreB_Mbl PF06723.8 AET38053.1 - 2.1e-06 26.5 0.1 5.1e-05 22.0 0.0 2.5 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 AET38053.1 - 0.02 14.7 0.3 0.13 12.1 0.0 2.3 2 1 0 2 2 2 0 Cell division protein FtsA EutA PF06277.6 AET38053.1 - 0.16 10.5 1.7 0.28 9.7 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA HSF_DNA-bind PF00447.12 AET38054.1 - 4.3e-37 126.4 2.9 4.3e-37 126.4 2.0 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Iso_dh PF00180.15 AET38055.1 - 3.1e-103 345.3 0.0 3.5e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ThiF PF00899.16 AET38056.1 - 3.2e-33 114.4 0.0 6.6e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 AET38056.1 - 1.3e-25 88.7 0.8 3.1e-25 87.5 0.5 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AET38056.1 - 3.8e-20 70.9 1.4 3.8e-20 70.9 1.0 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 AET38056.1 - 0.0068 16.4 0.6 0.053 13.6 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 AET38056.1 - 0.0071 16.4 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 AET38056.1 - 0.021 15.0 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding RhoGAP PF00620.22 AET38057.1 - 1.6e-31 108.9 0.1 3e-18 65.8 0.0 2.6 2 0 0 2 2 2 2 RhoGAP domain BAR PF03114.13 AET38058.1 - 5.6e-57 192.8 8.0 7.6e-57 192.4 5.5 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 AET38058.1 - 1.1e-12 47.0 0.0 2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AET38058.1 - 6.1e-12 44.9 0.0 1.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AET38058.1 - 1.6e-06 27.4 0.0 3.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Sugar_tr PF00083.19 AET38059.1 - 3e-78 263.4 28.4 2.8e-45 154.7 3.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 AET38059.1 - 5.8e-23 81.1 19.0 5.8e-23 81.1 13.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ERCC4 PF02732.10 AET38060.1 - 3.9e-26 91.5 0.1 7.9e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 AET38060.1 - 0.00017 21.7 0.0 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain GTP_EFTU PF00009.22 AET38061.1 - 1.4e-63 213.7 0.1 2.1e-63 213.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AET38061.1 - 9.5e-36 121.9 0.0 2.7e-35 120.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 AET38061.1 - 2.4e-21 75.3 0.0 6.7e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 AET38061.1 - 1.3e-13 50.5 0.0 4.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 AET38061.1 - 3.5e-12 46.2 1.2 1.1e-11 44.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AET38061.1 - 5.4e-06 26.3 0.2 1.2e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 AET38061.1 - 0.11 12.0 0.5 0.46 9.9 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PX PF00787.19 AET38062.1 - 7.3e-11 41.8 0.0 3.1e-10 39.8 0.0 2.1 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 AET38062.1 - 1.5e-07 30.9 12.4 2.6e-07 30.1 8.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like Arfaptin PF06456.8 AET38062.1 - 0.00031 20.1 0.9 0.011 15.0 0.0 2.5 2 0 0 2 2 2 1 Arfaptin-like domain Flexi_CP_N PF08358.5 AET38062.1 - 0.0025 17.5 0.0 0.26 11.0 0.0 3.2 3 1 0 3 3 3 1 Carlavirus coat Grp1_Fun34_YaaH PF01184.14 AET38063.1 - 3.8e-65 219.1 20.6 4.7e-65 218.8 14.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family WHIM1 PF15612.1 AET38064.1 - 0.0082 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PI-PLC-X PF00388.14 AET38065.1 - 3.6e-19 68.6 0.0 1.1e-18 66.9 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain WD40 PF00400.27 AET38066.1 - 0.41 10.6 3.5 9.6 6.2 0.1 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat BPL_LplA_LipB PF03099.14 AET38067.1 - 5.1e-18 65.2 0.2 9.1e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family UPF0086 PF01868.11 AET38068.1 - 1.2e-12 47.2 0.0 2.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF1366 PF07104.6 AET38068.1 - 0.065 12.8 0.6 0.097 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) COMPASS-Shg1 PF05205.7 AET38069.1 - 9.9e-21 74.0 1.8 1.2e-20 73.7 1.2 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF3333 PF11812.3 AET38069.1 - 0.04 13.9 0.2 0.076 13.0 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3333) SecY PF00344.15 AET38071.1 - 1e-49 169.3 22.5 1.4e-49 168.8 15.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AET38071.1 - 4e-06 26.2 0.0 1.2e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Methyltransf_PK PF05891.7 AET38073.1 - 1.4e-87 292.5 0.0 1.6e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 AET38073.1 - 0.00025 20.7 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET38073.1 - 0.00026 21.5 0.0 0.00044 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET38073.1 - 0.0032 17.7 0.0 0.0052 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AET38073.1 - 0.0045 17.4 0.0 0.0073 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Arb1 PF09692.5 AET38073.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 RhoGAP PF00620.22 AET38074.1 - 5.1e-40 136.5 0.3 4.6e-39 133.4 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 AET38074.1 - 3.2e-12 46.4 1.9 3.6e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain MCM_N PF14551.1 AET38074.1 - 0.16 12.5 3.3 4.9 7.6 0.0 2.9 2 1 1 3 3 3 0 MCM N-terminal domain Cullin PF00888.17 AET38075.1 - 1.1e-08 34.1 1.0 4.3e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Cullin family Dehydratase_LU PF02286.10 AET38075.1 - 0.039 12.2 0.0 0.058 11.6 0.0 1.2 1 0 0 1 1 1 0 Dehydratase large subunit EMP24_GP25L PF01105.19 AET38076.1 - 1e-43 149.1 0.0 1.3e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PH_3 PF14593.1 AET38076.1 - 0.046 13.6 0.1 0.067 13.0 0.1 1.2 1 0 0 1 1 1 0 PH domain Metallophos PF00149.23 AET38077.1 - 3.7e-44 150.5 0.1 4.4e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_6 PF13964.1 AET38078.1 - 2e-14 53.0 0.4 4.2e-05 23.5 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 AET38078.1 - 3.6e-14 52.2 4.1 7.6e-05 22.3 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 AET38078.1 - 1.1e-13 50.4 1.0 1.1e-05 24.8 0.0 4.3 3 1 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 AET38078.1 - 5.9e-05 22.9 0.5 0.0051 16.7 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 AET38078.1 - 6.4e-05 23.0 2.1 1.5 9.0 0.0 5.1 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 AET38078.1 - 0.00014 21.4 1.3 0.028 14.1 0.0 3.7 3 0 0 3 3 3 1 Kelch motif DUF793 PF05633.6 AET38078.1 - 0.98 8.1 4.3 2 7.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF793) DUF3554 PF12074.3 AET38079.1 - 2.7e-47 161.8 29.5 7.1e-25 88.1 0.9 7.2 7 1 0 7 7 7 2 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 AET38079.1 - 1.3e-35 121.5 29.0 7.7e-10 38.9 0.0 14.0 6 3 7 13 13 13 9 HEAT repeats HEAT PF02985.17 AET38079.1 - 6.7e-33 109.8 24.7 0.023 14.7 0.0 20.8 23 0 0 23 23 23 8 HEAT repeat HEAT_EZ PF13513.1 AET38079.1 - 6.2e-29 99.7 30.2 0.0025 18.2 0.0 17.7 10 5 8 18 18 18 9 HEAT-like repeat CLASP_N PF12348.3 AET38079.1 - 4e-21 75.4 0.1 1e-05 25.0 0.0 7.3 6 2 2 8 8 8 4 CLASP N terminal Vac14_Fab1_bd PF12755.2 AET38079.1 - 2.6e-10 40.5 2.6 0.095 13.0 0.0 8.6 7 2 1 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 AET38079.1 - 3.4e-10 40.0 17.0 0.0069 16.2 0.2 9.6 7 2 1 9 9 9 4 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 AET38079.1 - 2e-05 24.4 2.5 1.4 8.9 0.0 8.0 7 3 3 10 10 10 1 Rix1 complex component involved in 60S ribosome maturation Zn_clus PF00172.13 AET38080.1 - 6.3e-08 32.4 10.1 1.4e-07 31.3 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hist_deacetyl PF00850.14 AET38081.1 - 5e-83 278.9 0.0 6.7e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RPAP2_Rtr1 PF04181.8 AET38083.1 - 2e-17 63.0 1.1 3.5e-17 62.2 0.7 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF2574 PF10836.3 AET38083.1 - 0.0095 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2574) DUF747 PF05346.6 AET38084.1 - 5.3e-95 318.2 19.9 7.8e-95 317.7 13.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family zf-UBR PF02207.15 AET38085.1 - 5.5e-14 51.6 13.4 5.5e-14 51.6 9.3 3.3 2 1 0 3 3 3 2 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 AET38086.1 - 1.1e-140 468.1 0.3 1.6e-140 467.6 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 AET38086.1 - 4.3e-28 98.2 32.4 4.3e-28 98.2 22.5 3.2 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 AET38086.1 - 5.1e-15 56.0 0.1 1.3e-14 54.7 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AET38086.1 - 5.2e-09 35.5 0.0 5.2e-07 29.0 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AET38086.1 - 6.4e-07 29.1 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AET38086.1 - 0.0011 18.5 0.0 0.0045 16.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AET38086.1 - 0.0013 18.2 0.1 0.0083 15.6 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 AET38086.1 - 0.015 15.5 0.0 0.055 13.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Nol1_Nop2_Fmu PF01189.12 AET38087.1 - 1.4e-76 257.5 0.0 2.5e-60 204.2 0.0 2.2 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 AET38087.1 - 0.00027 20.9 0.0 0.00095 19.1 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF1887 PF09002.6 AET38087.1 - 0.034 12.5 0.0 0.053 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Methyltransf_26 PF13659.1 AET38087.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 AET38087.1 - 0.082 13.4 0.0 0.27 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UAF_Rrn10 PF05234.6 AET38088.1 - 7.2e-27 93.8 0.0 8.8e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 UAF complex subunit Rrn10 V_ATPase_I PF01496.14 AET38089.1 - 1.2e-273 909.6 6.3 1.4e-273 909.4 4.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Lge1 PF11488.3 AET38089.1 - 0.14 12.3 1.1 0.31 11.2 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 WD40 PF00400.27 AET38090.1 - 4.5e-32 108.7 18.2 4.8e-08 32.5 1.3 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 AET38090.1 - 6.3e-05 21.3 2.0 0.009 14.1 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Pkinase PF00069.20 AET38091.1 - 5.9e-57 192.7 0.1 1.3e-53 181.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AET38091.1 - 7.7e-20 71.0 0.2 2.1e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AET38091.1 - 0.15 11.7 0.9 0.53 9.9 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family TBCA PF02970.11 AET38093.1 - 4.3e-27 94.0 6.8 5.2e-27 93.7 4.7 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A ACCA PF03255.9 AET38093.1 - 0.00085 18.8 2.0 0.0011 18.5 1.4 1.1 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit AAA_13 PF13166.1 AET38093.1 - 0.017 13.6 2.3 0.018 13.5 1.6 1.0 1 0 0 1 1 1 0 AAA domain DUF2353 PF09789.4 AET38093.1 - 0.051 12.8 4.3 0.075 12.2 2.8 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Cullin_Nedd8 PF10557.4 AET38093.1 - 0.055 13.3 0.1 0.087 12.6 0.1 1.5 1 1 0 1 1 1 0 Cullin protein neddylation domain PolC_DP2 PF03833.8 AET38093.1 - 0.056 11.1 3.1 0.063 10.9 2.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PSII_Pbs27 PF13326.1 AET38093.1 - 0.059 13.3 0.4 0.069 13.1 0.3 1.1 1 0 0 1 1 1 0 Photosystem II Pbs27 MutS_III PF05192.13 AET38093.1 - 0.081 12.6 0.1 0.092 12.5 0.1 1.1 1 0 0 1 1 1 0 MutS domain III DUF2397 PF09660.5 AET38093.1 - 0.093 11.3 1.5 0.12 10.8 1.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2397) DUF1048 PF06304.6 AET38093.1 - 0.1 12.9 1.6 0.6 10.4 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1048) DUF342 PF03961.8 AET38093.1 - 0.24 9.7 1.4 0.26 9.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 AET38093.1 - 0.29 10.7 3.6 0.36 10.3 2.5 1.3 1 0 0 1 1 1 0 IncA protein Spectrin PF00435.16 AET38093.1 - 0.64 10.3 5.3 6.8 7.0 1.8 2.1 1 1 0 2 2 2 0 Spectrin repeat DUF3010 PF11215.3 AET38093.1 - 0.73 9.7 2.8 17 5.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3010) ATP_bind_1 PF03029.12 AET38095.1 - 3e-76 256.1 0.0 3.8e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 AET38095.1 - 0.003 18.3 1.7 0.013 16.3 0.0 2.7 2 2 0 2 2 2 1 AAA domain ArgK PF03308.11 AET38095.1 - 0.0049 15.6 0.0 0.0099 14.6 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 AET38095.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 AET38095.1 - 0.011 15.7 0.1 0.076 12.9 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 AET38095.1 - 0.028 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AET38095.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KTI12 PF08433.5 AET38095.1 - 0.052 12.7 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CbiA PF01656.18 AET38095.1 - 0.067 12.5 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MitMem_reg PF13012.1 AET38096.1 - 9e-39 132.1 1.1 9e-39 132.1 0.7 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 AET38096.1 - 2.4e-28 98.1 0.0 4.6e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease His_Phos_1 PF00300.17 AET38096.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) UbiA PF01040.13 AET38097.1 - 5.8e-24 84.6 19.5 5.8e-24 84.6 13.5 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family AAA PF00004.24 AET38098.1 - 8.7e-43 145.6 0.0 1.7e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AET38098.1 - 1.7e-07 31.3 0.1 3.2e-05 24.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 AET38098.1 - 1.2e-06 28.3 0.2 3.1e-05 23.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AET38098.1 - 2.4e-05 24.2 0.0 8.4e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AET38098.1 - 5.4e-05 23.3 0.1 0.0042 17.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 AET38098.1 - 7.2e-05 21.9 0.0 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AET38098.1 - 0.00015 21.4 0.1 0.00031 20.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 AET38098.1 - 0.00049 20.9 1.1 0.0014 19.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 AET38098.1 - 0.0013 17.5 0.1 0.0024 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus UPF0079 PF02367.12 AET38098.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 AET38098.1 - 0.0015 18.6 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 AET38098.1 - 0.0017 17.8 0.1 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 AET38098.1 - 0.004 16.3 0.1 0.0085 15.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 AET38098.1 - 0.0053 16.1 0.6 0.035 13.5 0.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 AET38098.1 - 0.0071 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AET38098.1 - 0.0073 16.6 0.8 0.041 14.1 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AET38098.1 - 0.0085 16.0 0.4 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 AET38098.1 - 0.011 15.2 1.1 0.016 14.7 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 AET38098.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AET38098.1 - 0.014 14.4 0.7 0.056 12.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin KaiC PF06745.8 AET38098.1 - 0.016 14.3 1.2 0.038 13.0 0.0 2.2 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 AET38098.1 - 0.022 14.0 0.1 0.046 12.9 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Spc7 PF08317.6 AET38098.1 - 0.028 13.0 4.5 0.045 12.4 3.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.6 AET38098.1 - 0.04 13.3 4.6 1.3 8.4 2.4 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 AAA_11 PF13086.1 AET38098.1 - 0.063 12.8 2.2 0.56 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 AET38098.1 - 0.069 12.6 0.2 0.3 10.5 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 AET38098.1 - 0.07 11.9 0.1 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 AET38098.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AET38098.1 - 0.085 12.5 0.1 0.31 10.6 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Fib_alpha PF08702.5 AET38098.1 - 0.23 11.5 1.9 0.56 10.3 1.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 AET38098.1 - 0.47 8.2 1.6 0.62 7.8 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 AET38098.1 - 0.52 10.5 12.0 6.1 7.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 AET38098.1 - 4.4 6.8 8.6 9 5.8 6.0 1.5 1 0 0 1 1 1 0 IncA protein MCRS_N PF13325.1 AET38098.1 - 7.3 6.0 8.1 1.5 8.2 3.0 1.7 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein EF-hand_1 PF00036.27 AET38100.1 - 8.8e-26 87.2 16.1 6.9e-08 31.2 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AET38100.1 - 2e-23 82.2 12.9 8.5e-14 51.4 1.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AET38100.1 - 2.1e-20 70.6 13.0 4.6e-07 29.1 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 AET38100.1 - 2.3e-19 68.7 15.8 1.7e-11 43.5 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 AET38100.1 - 6.7e-19 66.3 8.2 4.8e-06 25.6 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 AET38100.1 - 5.5e-09 35.7 1.5 0.00015 21.4 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AET38100.1 - 3.2e-08 33.3 0.5 9.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain VCBS PF13517.1 AET38100.1 - 0.015 15.6 0.3 0.55 10.6 0.0 2.3 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MgtE_N PF03448.12 AET38100.1 - 0.019 15.2 2.9 0.047 14.0 0.1 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain SPARC_Ca_bdg PF10591.4 AET38100.1 - 0.036 14.1 0.5 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 AET38100.1 - 0.1 12.1 0.5 0.6 9.6 0.0 2.3 2 2 1 3 3 3 0 Caleosin related protein Toprim_2 PF13155.1 AET38100.1 - 0.15 12.4 1.5 18 5.7 0.1 2.6 2 1 0 2 2 2 0 Toprim-like CAP_GLY PF01302.20 AET38101.1 - 9.8e-22 76.4 0.9 1.6e-21 75.7 0.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain Orthopox_35kD PF02250.10 AET38101.1 - 0.02 14.1 2.1 0.038 13.2 1.5 1.5 1 0 0 1 1 1 0 35kD major secreted virus protein MtrG PF04210.8 AET38101.1 - 0.45 10.2 3.6 15 5.3 0.2 3.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4279 PF14106.1 AET38101.1 - 0.49 10.2 7.9 0.73 9.7 0.5 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4279) DUF4201 PF13870.1 AET38101.1 - 0.57 9.6 39.0 2.3 7.6 10.0 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) GAS PF13851.1 AET38101.1 - 0.63 9.2 47.3 0.69 9.0 12.9 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CHD5 PF04420.9 AET38101.1 - 7.5 6.1 13.7 0.051 13.2 1.0 3.1 2 1 1 3 3 3 0 CHD5-like protein Carbpep_Y_N PF05388.6 AET38101.1 - 9.1 6.4 9.6 3.1 7.9 1.1 3.7 3 1 1 4 4 4 0 Carboxypeptidase Y pro-peptide PIGA PF08288.7 AET38102.1 - 3.7e-45 152.2 3.5 1.4e-44 150.3 2.5 2.1 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 AET38102.1 - 7.2e-30 103.6 0.0 1.1e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AET38102.1 - 1.1e-16 61.0 0.9 2.1e-16 60.1 0.6 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 AET38102.1 - 2.5e-13 50.5 0.0 4.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 AET38102.1 - 9.5e-11 41.9 0.0 2.3e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AET38102.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 TFR_dimer PF04253.10 AET38103.1 - 1.4e-31 108.6 0.1 2.6e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 AET38103.1 - 0.087 12.5 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 PA domain Cyt-b5 PF00173.23 AET38104.1 - 1.9e-13 50.0 0.1 2.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PEHE PF15275.1 AET38105.1 - 0.11 12.9 0.4 0.11 12.9 0.3 2.5 2 1 1 3 3 3 0 PEHE domain TAP_C PF03943.8 AET38106.1 - 1.2e-14 53.4 0.5 1.1e-13 50.2 0.0 2.5 2 0 0 2 2 2 1 TAP C-terminal domain LRR_9 PF14580.1 AET38106.1 - 2.8e-06 27.0 0.4 5e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 AET38106.1 - 3.5e-06 26.4 6.4 0.00029 20.3 1.2 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AET38106.1 - 0.0016 18.2 0.3 6.9 7.0 0.1 3.8 3 0 0 3 3 3 1 Leucine Rich repeat LRR_7 PF13504.1 AET38106.1 - 0.027 14.6 0.7 38 5.1 0.0 3.8 3 0 0 3 3 3 0 Leucine rich repeat Lycopene_cycl PF05834.7 AET38106.1 - 0.14 11.0 0.3 0.4 9.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Sec63 PF02889.11 AET38107.1 - 9.2e-19 67.7 0.1 1.6e-16 60.4 0.0 2.1 1 1 1 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 AET38107.1 - 1.3e-15 56.8 0.2 3e-15 55.6 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Acetyltransf_1 PF00583.19 AET38108.1 - 2.8e-15 56.1 0.3 4.1e-15 55.5 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AET38108.1 - 9.3e-09 35.3 0.1 1.5e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AET38108.1 - 2e-07 31.0 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AET38108.1 - 5.1e-06 26.6 0.0 6.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AET38108.1 - 0.00077 19.1 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 AET38108.1 - 0.016 15.3 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 AET38108.1 - 0.058 13.0 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AET38108.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 AET38108.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4177 PF13783.1 AET38109.1 - 0.014 14.9 0.0 0.042 13.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) DUF2962 PF11176.3 AET38110.1 - 2.4e-51 173.3 8.5 2.7e-51 173.1 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DNA_pol_B PF00136.16 AET38111.1 - 4.4e-95 319.1 0.6 6.5e-95 318.6 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AET38111.1 - 6.1e-20 71.3 0.3 1.7e-11 43.6 0.2 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AET38111.1 - 4.9e-10 39.2 7.6 1e-09 38.2 5.3 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF3939 PF13075.1 AET38112.1 - 0.12 12.1 0.1 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) SET PF00856.23 AET38113.1 - 5e-10 39.9 0.4 1.9e-09 38.0 0.3 2.1 1 1 0 1 1 1 1 SET domain SmpA_OmlA PF04355.8 AET38113.1 - 0.093 12.3 0.0 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 SmpA / OmlA family Rhodanese PF00581.15 AET38114.1 - 8.9e-19 67.9 0.0 1.1e-09 38.5 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Clp1 PF06807.9 AET38115.1 - 1e-17 64.5 0.1 1.7e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 AET38115.1 - 1.5e-07 31.2 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AET38115.1 - 0.00034 20.5 0.1 0.0019 18.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AET38115.1 - 0.00065 19.7 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 AET38115.1 - 0.0024 18.7 0.4 0.0054 17.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AET38115.1 - 0.0065 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 AET38115.1 - 0.011 16.0 0.1 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 AET38115.1 - 0.013 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 AET38115.1 - 0.022 13.7 0.0 0.048 12.6 0.0 1.5 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.12 AET38115.1 - 0.026 14.0 0.1 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 AET38115.1 - 0.027 13.9 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 AET38115.1 - 0.03 13.8 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 AET38115.1 - 0.052 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 AET38115.1 - 0.053 12.4 0.2 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.1 AET38115.1 - 0.053 13.3 0.2 0.1 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AET38115.1 - 0.058 13.6 0.6 0.24 11.7 0.4 2.0 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 AET38115.1 - 0.085 11.5 0.2 1.4 7.5 0.1 2.0 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 AET38115.1 - 0.099 11.8 0.0 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 AET38115.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.18 AET38115.1 - 0.12 12.1 0.3 1.7 8.4 0.0 2.4 3 0 0 3 3 3 0 Dynamin family AAA_28 PF13521.1 AET38115.1 - 0.16 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Apc5 PF12862.2 AET38116.1 - 7.7e-20 70.5 4.9 1.1e-19 70.0 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 Apc3 PF12895.2 AET38116.1 - 0.029 14.5 0.1 0.52 10.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CBM_25 PF03423.8 AET38116.1 - 0.052 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) CM1 PF03026.10 AET38116.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Influenza C virus M1 protein HATPase_c_3 PF13589.1 AET38117.1 - 1.4e-11 44.2 0.0 2.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 AET38117.1 - 3.5e-10 39.6 0.0 2.4e-08 33.6 0.0 2.4 1 1 1 2 2 2 2 MutL C terminal dimerisation domain HATPase_c PF02518.21 AET38117.1 - 1.4e-08 34.3 0.1 2.7e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3661 PF12400.3 AET38119.1 - 5.6e-43 146.1 7.7 5.6e-43 146.1 5.3 1.5 2 0 0 2 2 2 1 Vaculolar membrane protein Nse4_C PF08743.5 AET38120.1 - 0.055 13.4 0.2 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Nse4 C-terminal adh_short PF00106.20 AET38121.1 - 3.2e-14 53.1 0.0 3e-13 50.0 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AET38121.1 - 9.4e-07 28.8 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 AET38121.1 - 0.002 18.1 0.0 0.94 9.4 0.0 2.4 1 1 1 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 AET38121.1 - 0.0048 16.3 0.1 0.0081 15.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 AET38121.1 - 0.016 14.8 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 KR domain DUF2839 PF10999.3 AET38121.1 - 0.13 12.3 1.7 1.2 9.1 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) tRNA-synt_1 PF00133.17 AET38122.1 - 1.1e-45 155.8 0.0 2.6e-37 128.1 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AET38122.1 - 8.2e-20 70.8 0.1 1.2e-10 40.6 0.0 4.1 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AET38122.1 - 6.1e-11 42.2 0.0 2.3e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AET38122.1 - 1.5e-06 27.5 0.0 3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pet20 PF08692.5 AET38123.1 - 3.5e-18 65.8 7.7 1e-09 38.4 0.0 3.0 3 1 1 4 4 4 2 Mitochondrial protein Pet20 Abhydrolase_6 PF12697.2 AET38124.1 - 6.7e-12 45.7 0.0 9.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET38124.1 - 8.8e-11 41.7 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AET38124.1 - 8.4e-06 25.6 0.0 1.9e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 AET38124.1 - 0.00063 19.3 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Cutinase PF01083.17 AET38124.1 - 0.0085 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF915 PF06028.6 AET38124.1 - 0.074 12.1 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Serpulina_VSP PF05540.6 AET38124.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein Methyltransf_15 PF09445.5 AET38126.1 - 4.2e-59 198.7 0.0 5.6e-59 198.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 AET38126.1 - 3.9e-07 29.8 0.0 6.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 AET38126.1 - 2.6e-06 27.0 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET38126.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AET38126.1 - 4.2e-05 22.9 0.0 7.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AET38126.1 - 0.00034 20.9 0.0 0.00065 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET38126.1 - 0.001 19.6 0.0 0.0018 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 AET38126.1 - 0.002 17.6 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.10 AET38126.1 - 0.0063 15.9 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 DNA_methylase PF00145.12 AET38126.1 - 0.048 12.7 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_23 PF13489.1 AET38126.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 AET38126.1 - 0.11 11.1 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Kinesin PF00225.18 AET38128.1 - 1.1e-104 349.8 0.7 1.1e-104 349.8 0.5 1.6 2 0 0 2 2 2 1 Kinesin motor domain TMF_DNA_bd PF12329.3 AET38128.1 - 1.4 8.8 16.4 0.35 10.6 1.5 4.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 AET38128.1 - 4.7 7.3 14.5 4.6 7.3 1.9 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Asp PF00026.18 AET38129.1 - 2.1e-99 332.7 0.3 2.5e-99 332.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AET38129.1 - 4.6e-09 36.4 0.0 4.6e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AET38129.1 - 6e-09 35.6 0.0 9.6e-07 28.4 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 AET38129.1 - 1.6e-05 25.3 0.0 0.0057 17.1 0.0 3.3 2 2 0 2 2 2 1 Aspartyl protease Pkinase PF00069.20 AET38130.1 - 6.2e-77 258.2 0.0 9.9e-77 257.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38130.1 - 1.2e-38 132.6 0.0 1.9e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AET38130.1 - 3.5e-25 87.8 3.4 9.1e-14 51.3 0.1 3.0 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.1 AET38130.1 - 3.2e-08 32.8 0.0 6e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AET38130.1 - 1.6e-05 24.0 0.0 2.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET38130.1 - 2e-05 24.4 0.0 0.017 14.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 AET38130.1 - 0.0029 16.9 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family DAGAT PF03982.8 AET38131.1 - 4.4e-84 281.6 3.9 4.1e-75 252.2 0.1 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase PTPA PF03095.10 AET38132.1 - 7.9e-118 392.9 0.4 9.3e-118 392.7 0.3 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF3826 PF12875.2 AET38132.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) MOZ_SAS PF01853.13 AET38133.1 - 4.7e-89 296.6 0.5 6.7e-89 296.1 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 AET38133.1 - 4.5e-23 80.7 0.1 9.4e-23 79.6 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 AET38133.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family WD40 PF00400.27 AET38134.1 - 8.2e-45 149.1 20.6 2e-10 40.1 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AET38134.1 - 2e-05 23.5 1.1 0.054 12.2 0.0 3.9 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 AET38134.1 - 0.0019 17.6 0.2 0.24 10.8 0.0 3.1 3 0 0 3 3 3 1 PQQ-like domain DUF1258 PF06869.7 AET38134.1 - 0.025 13.6 0.4 0.063 12.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) Nup160 PF11715.3 AET38134.1 - 0.035 12.2 8.9 1.1 7.2 0.1 4.1 1 1 4 5 5 5 0 Nucleoporin Nup120/160 TruD PF01142.13 AET38135.1 - 4.2e-68 229.7 0.1 4.4e-63 213.2 0.0 3.5 1 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DASH_Dad1 PF08649.5 AET38135.1 - 0.037 13.7 1.9 5.7 6.7 0.3 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad1 RRM_5 PF13893.1 AET38136.1 - 0.0029 17.4 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET38136.1 - 0.0056 16.2 0.0 0.02 14.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET38136.1 - 0.1 12.6 0.0 4.1 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mur_ligase_M PF08245.7 AET38137.1 - 4.2e-06 26.9 1.3 0.00031 20.8 0.2 3.0 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 AET38137.1 - 0.0084 16.1 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Pkinase PF00069.20 AET38138.1 - 4.6e-64 216.0 0.0 7.5e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38138.1 - 7.3e-35 120.2 0.0 1.1e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38138.1 - 4.4e-08 32.4 0.0 2.2e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AET38138.1 - 0.01 14.9 0.0 0.03 13.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET38138.1 - 0.2 11.3 0.0 0.43 10.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SGT1 PF07093.6 AET38139.1 - 3e-38 131.5 17.8 7e-31 107.2 0.2 2.1 2 0 0 2 2 2 2 SGT1 protein APG5 PF04106.7 AET38140.1 - 6.9e-47 159.4 0.1 8.3e-47 159.2 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 ACPS PF01648.15 AET38141.1 - 1.1e-13 51.0 0.0 2.6e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PP2 PF14299.1 AET38141.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Phloem protein 2 ABC_membrane_2 PF06472.10 AET38142.1 - 3.1e-87 292.2 9.6 3.1e-87 292.2 6.6 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AET38142.1 - 9.1e-15 55.1 0.0 2.7e-14 53.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.14 AET38142.1 - 0.0003 20.0 0.5 0.029 13.5 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 AET38142.1 - 0.046 13.1 0.0 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 AET38142.1 - 0.098 12.5 0.2 1.3 8.9 0.3 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Nop53 PF07767.6 AET38144.1 - 1.1e-88 297.9 36.9 1.3e-88 297.6 25.6 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4404 PF14357.1 AET38144.1 - 3 8.3 14.6 1.6 9.1 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Oxysterol_BP PF01237.13 AET38145.1 - 8.6e-93 310.6 1.7 1.1e-92 310.2 1.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DHFR_1 PF00186.14 AET38146.1 - 1.1e-26 93.3 0.0 1.8e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrofolate reductase chaperone_DMP PF10448.4 AET38147.1 - 2.8e-12 46.7 0.1 3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 20S proteasome chaperone Pyr_redox_3 PF13738.1 AET38148.1 - 1e-29 104.0 0.0 2e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AET38148.1 - 1.6e-21 76.0 0.8 2.7e-15 55.5 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 AET38148.1 - 5.6e-15 55.0 0.2 4.7e-12 45.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AET38148.1 - 5e-14 52.6 0.0 1.9e-13 50.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AET38148.1 - 4.4e-06 25.9 0.2 9.5e-05 21.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AET38148.1 - 5.7e-05 23.0 0.0 0.00089 19.2 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 AET38148.1 - 0.00026 20.1 0.1 0.026 13.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 AET38148.1 - 0.00037 20.7 0.0 1.2 9.3 0.0 2.8 3 0 0 3 3 3 2 Putative NAD(P)-binding Pyr_redox PF00070.22 AET38148.1 - 0.00046 20.5 0.4 0.62 10.5 0.1 3.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AET38148.1 - 0.005 15.7 0.3 0.1 11.4 0.1 2.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AET38148.1 - 0.0066 15.3 0.2 0.016 14.0 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 AET38148.1 - 0.017 15.1 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 AET38148.1 - 0.049 13.4 0.4 13 5.4 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.13 AET38148.1 - 0.078 12.9 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain CPSase_L_chain PF00289.17 AET38148.1 - 0.078 13.0 0.0 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 AET38148.1 - 0.12 11.2 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 AET38148.1 - 0.14 11.2 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 AET38148.1 - 0.16 11.6 0.0 15 5.1 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S25 PF03297.10 AET38149.1 - 3.4e-45 152.3 4.6 3.8e-45 152.2 3.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 AET38149.1 - 0.00044 19.9 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 AET38149.1 - 0.04 13.2 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 CodY helix-turn-helix domain Thg1 PF04446.7 AET38151.1 - 7.4e-46 155.1 0.4 9.7e-46 154.7 0.3 1.1 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 AET38151.1 - 3e-36 123.7 0.2 5.1e-36 123.0 0.2 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Cu-oxidase PF00394.17 AET38152.1 - 0.051 13.4 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Multicopper oxidase RNA_pol_Rpb2_6 PF00562.23 AET38153.1 - 1.5e-114 382.7 0.0 2.1e-114 382.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AET38153.1 - 3.2e-47 160.1 0.1 4.5e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AET38153.1 - 1.4e-34 119.1 0.0 7.5e-34 116.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 AET38153.1 - 2.3e-24 84.9 0.0 8.6e-24 83.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 AET38153.1 - 2.4e-22 78.6 0.0 4.9e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 AET38153.1 - 1.4e-15 57.2 0.0 8.8e-15 54.7 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 AET38153.1 - 4.3e-06 26.5 0.1 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF572 PF04502.8 AET38155.1 - 6.1e-49 166.9 26.2 2e-48 165.3 18.2 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) Mu-like_Com PF10122.4 AET38155.1 - 0.012 14.6 0.4 0.089 11.8 0.1 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com Tox-ODYAM1 PF15642.1 AET38155.1 - 0.032 12.9 4.0 0.045 12.4 2.8 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TF_Zn_Ribbon PF08271.7 AET38155.1 - 0.081 12.2 0.3 0.23 10.7 0.2 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Zn_Tnp_IS1 PF03811.8 AET38155.1 - 0.082 12.4 1.2 0.36 10.3 0.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain zf-FPG_IleRS PF06827.9 AET38155.1 - 0.11 12.2 0.9 7 6.4 0.1 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF1266 PF06889.6 AET38155.1 - 2 8.1 7.5 3.8 7.2 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) DUF607 PF04678.8 AET38155.1 - 7.5 6.4 8.3 12 5.8 3.5 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF607 DUF2812 PF11193.3 AET38156.1 - 0.19 11.8 2.0 0.4 10.8 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) FYVE_2 PF02318.11 AET38156.1 - 0.27 11.1 7.0 4 7.3 1.2 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger zf-DHHC PF01529.15 AET38156.1 - 1.1 8.6 9.9 0.6 9.4 0.3 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase GRP PF07172.6 AET38156.1 - 1.6 9.2 7.4 0.085 13.3 1.0 1.8 2 0 0 2 2 2 0 Glycine rich protein family UPF1_Zn_bind PF09416.5 AET38157.1 - 3.2e-66 221.6 13.2 3.2e-66 221.6 9.1 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 AET38157.1 - 2.6e-57 193.4 0.0 7.1e-57 192.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AET38157.1 - 1.1e-52 179.0 1.3 1.1e-52 179.0 0.9 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AET38157.1 - 1.6e-14 53.9 0.1 1.3e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AET38157.1 - 7.5e-13 48.0 0.0 2.5e-12 46.3 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 AET38157.1 - 2.8e-06 27.3 0.0 7.1e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 AET38157.1 - 1.8e-05 23.9 0.2 0.00045 19.2 0.0 3.2 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 AET38157.1 - 0.00055 19.6 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 Helicase PhoH PF02562.11 AET38157.1 - 0.0019 17.4 0.0 0.0043 16.2 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.24 AET38157.1 - 0.002 17.6 0.1 0.0053 16.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 AET38157.1 - 0.0073 15.2 0.1 1.6 7.5 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase T2SE PF00437.15 AET38157.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 AET38157.1 - 0.035 13.5 0.0 0.082 12.3 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Ribosomal_S13_N PF08069.7 AET38157.1 - 0.038 13.8 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 AET38157.1 - 0.04 14.0 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AET38157.1 - 0.059 13.3 0.2 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 AET38157.1 - 0.063 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC CRAL_TRIO PF00650.15 AET38158.1 - 3.9e-35 120.6 0.0 5.5e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AET38158.1 - 1e-11 44.7 1.8 3e-11 43.2 1.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AET38158.1 - 0.00034 20.5 0.0 0.00066 19.5 0.0 1.4 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3303 PF11746.3 AET38158.1 - 0.037 14.3 0.2 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) BACK PF07707.10 AET38158.1 - 0.14 12.0 0.1 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch AAA PF00004.24 AET38159.1 - 6.1e-12 45.8 0.2 5e-11 42.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AET38159.1 - 5.9e-09 35.1 1.3 0.00049 18.9 0.0 2.5 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 AET38159.1 - 2.3e-06 28.4 0.0 9.5e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AET38159.1 - 0.00019 21.3 0.0 0.00043 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AET38159.1 - 0.0003 20.6 0.0 0.00077 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AET38159.1 - 0.00043 20.4 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AET38159.1 - 0.00067 18.7 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AET38159.1 - 0.0018 18.2 0.2 0.0072 16.3 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 AET38159.1 - 0.006 16.3 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 AET38159.1 - 0.0069 16.6 0.0 0.025 14.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 AET38159.1 - 0.016 14.7 1.4 0.034 13.7 0.9 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AET38159.1 - 0.051 12.9 0.1 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 AET38159.1 - 0.051 13.1 0.2 0.17 11.4 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 AET38159.1 - 0.071 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 AET38159.1 - 2.8 8.2 7.8 2.3e+02 1.9 5.4 3.1 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 AET38160.1 - 2.6e-10 40.0 15.5 6.3e-10 38.8 10.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor V_ATPase_I PF01496.14 AET38160.1 - 0.00013 20.0 2.7 0.00015 19.8 1.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Glutaredoxin2_C PF04399.8 AET38160.1 - 0.00035 20.1 2.5 0.0012 18.4 2.0 1.6 2 0 0 2 2 2 1 Glutaredoxin 2, C terminal domain CASP_C PF08172.7 AET38160.1 - 0.0077 15.2 3.5 0.011 14.8 2.4 1.2 1 0 0 1 1 1 1 CASP C terminal SlyX PF04102.7 AET38160.1 - 0.019 15.3 0.8 0.037 14.4 0.6 1.5 1 0 0 1 1 1 0 SlyX PSI_PsaF PF02507.10 AET38160.1 - 0.04 13.4 0.4 0.064 12.8 0.3 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III bHLH-MYC_N PF14215.1 AET38160.1 - 0.065 13.4 0.1 0.093 12.9 0.1 1.2 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal bZIP_2 PF07716.10 AET38160.1 - 0.17 11.7 20.0 0.35 10.7 13.8 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF349 PF03993.7 AET38160.1 - 0.22 11.7 10.0 0.41 10.8 6.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) bZIP_Maf PF03131.12 AET38160.1 - 0.25 11.6 9.6 0.43 10.8 6.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6 PF04111.7 AET38160.1 - 0.3 10.0 7.0 0.44 9.5 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Toxin_43 PF15604.1 AET38160.1 - 0.41 10.6 7.6 0.19 11.7 3.7 1.5 2 0 0 2 2 1 0 Putative toxin 43 IncA PF04156.9 AET38160.1 - 0.47 10.0 6.2 0.83 9.2 4.3 1.3 1 0 0 1 1 1 0 IncA protein RIC3 PF15361.1 AET38160.1 - 0.78 9.9 4.3 1.4 9.1 3.0 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4140 PF13600.1 AET38160.1 - 1.3 9.5 5.3 1.2 9.5 2.0 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 AET38160.1 - 1.7 7.5 5.7 2.7 6.8 4.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 AET38160.1 - 4.4 6.1 6.4 7.6 5.3 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bap31 PF05529.7 AET38160.1 - 9.6 5.6 7.7 15 4.9 5.4 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like 2OG-FeII_Oxy_3 PF13640.1 AET38161.1 - 4.5e-10 39.9 0.1 7.2e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AET38161.1 - 0.00015 22.0 0.1 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 AET38161.1 - 0.00024 20.6 0.2 0.0004 19.9 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 AET38161.1 - 0.0091 14.8 0.0 0.023 13.4 0.0 1.6 1 1 0 1 1 1 1 Poxvirus C4/C10 protein CUE PF02845.11 AET38162.1 - 8.3e-14 50.7 0.4 1.7e-09 36.9 0.0 2.8 2 0 0 2 2 2 2 CUE domain Smr PF01713.16 AET38162.1 - 3.3e-12 46.4 0.0 6.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Smr domain DMA PF03474.9 AET38162.1 - 2.2e-06 27.4 0.0 0.0014 18.4 0.0 3.2 3 0 0 3 3 3 2 DMRTA motif CENP-C_C PF11699.3 AET38163.1 - 2.3e-27 94.7 1.2 5e-27 93.7 0.8 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 AET38163.1 - 1.3e-21 77.6 0.6 1.3e-21 77.6 0.4 3.7 2 1 3 5 5 5 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 AET38163.1 - 0.00048 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AT_hook PF02178.14 AET38163.1 - 0.021 14.4 4.1 0.065 12.9 2.9 1.9 1 0 0 1 1 1 0 AT hook motif Pkinase PF00069.20 AET38164.1 - 2e-71 240.1 0.0 2e-71 240.1 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38164.1 - 1.3e-46 158.8 0.0 2.5e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 AET38164.1 - 4.3e-22 78.2 4.4 1.4e-21 76.6 0.1 3.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 AET38164.1 - 7e-06 25.2 0.1 2.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AET38164.1 - 0.12 12.0 4.2 0.14 11.8 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family HECT PF00632.20 AET38165.1 - 1.4e-74 251.0 0.0 3e-74 250.0 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L10 PF00466.15 AET38166.1 - 7.6e-16 57.8 0.1 1.1e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Dynactin_p22 PF07426.6 AET38166.1 - 0.077 12.2 0.1 7.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 Ribosomal_S2 PF00318.15 AET38168.1 - 2.3e-59 200.1 0.0 2.6e-58 196.7 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S2 TRAM_LAG1_CLN8 PF03798.11 AET38169.1 - 1.3e-37 129.3 22.7 1.3e-37 129.3 15.7 2.2 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 AET38169.1 - 2.5e-24 84.5 2.5 7.2e-24 83.0 1.8 1.8 1 0 0 1 1 1 1 TRAM1-like protein HIF-1 PF11413.3 AET38169.1 - 0.13 11.4 0.0 0.57 9.4 0.0 1.9 2 0 0 2 2 2 0 Hypoxia-inducible factor-1 Herpes_LMP1 PF05297.6 AET38169.1 - 5.5 5.8 6.1 9.1 5.0 4.2 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) VHS PF00790.14 AET38170.1 - 1.4e-28 99.3 2.1 2e-28 98.7 0.4 2.0 2 0 0 2 2 2 1 VHS domain SH3_9 PF14604.1 AET38170.1 - 3.5e-15 55.3 0.0 5.7e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AET38170.1 - 2.7e-14 52.2 0.0 4.7e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AET38170.1 - 6.1e-12 44.8 0.0 1.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DivIVA PF05103.8 AET38170.1 - 0.018 15.1 7.5 0.6 10.1 2.5 2.6 2 0 0 2 2 2 0 DivIVA protein DUF972 PF06156.8 AET38170.1 - 0.55 10.6 0.1 0.55 10.6 0.0 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF972) F-actin_cap_A PF01267.12 AET38171.1 - 8e-69 231.6 0.7 9.1e-69 231.5 0.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF4492 PF14899.1 AET38172.1 - 0.12 11.8 0.6 0.21 11.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Synaptobrevin PF00957.16 AET38172.1 - 0.19 11.3 2.2 0.45 10.1 1.5 1.7 1 1 0 1 1 1 0 Synaptobrevin Ribosomal_L14e PF01929.12 AET38173.1 - 2.4e-29 101.5 0.4 3.7e-29 100.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 AET38173.1 - 4.2e-05 23.1 0.7 7.8e-05 22.2 0.5 1.5 1 0 0 1 1 1 1 KOW motif Ribosomal_S6 PF01250.12 AET38174.1 - 4.7e-07 29.5 0.0 6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 SCIMP PF15050.1 AET38174.1 - 0.13 12.1 0.1 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 SCIMP protein Snf7 PF03357.16 AET38175.1 - 6.6e-30 103.7 20.3 6.6e-30 103.7 14.1 1.4 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 AET38175.1 - 7.2e-07 28.7 7.0 9.2e-07 28.4 4.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Pollen_allerg_2 PF01620.11 AET38175.1 - 0.18 12.1 0.6 0.29 11.4 0.4 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) DUF87 PF01935.12 AET38175.1 - 0.48 10.1 5.4 3.5 7.3 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 AET38175.1 - 0.67 7.7 4.5 0.81 7.4 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Remorin_C PF03763.8 AET38175.1 - 1.9 8.0 11.3 3.6 7.1 7.8 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region HSCB_C PF07743.8 AET38175.1 - 3.7 8.0 12.6 0.41 11.1 3.1 2.5 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain PBP_sp32 PF07222.7 AET38175.1 - 5 6.2 8.3 2.8 7.0 3.5 1.9 2 0 0 2 2 2 0 Proacrosin binding protein sp32 APS_kinase PF01583.15 AET38176.1 - 1.8e-70 235.6 0.0 2.3e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 AET38176.1 - 3.4e-08 33.4 0.0 6.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AET38176.1 - 7.2e-05 23.5 0.1 0.00012 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 AET38176.1 - 0.00031 20.0 0.0 0.00053 19.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 AET38176.1 - 0.00063 20.0 0.1 0.0021 18.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AET38176.1 - 0.0056 16.1 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 AET38176.1 - 0.02 14.9 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain CPT PF07931.7 AET38176.1 - 0.052 13.1 0.1 0.18 11.4 0.1 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 AET38176.1 - 0.058 13.7 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter CbiA PF01656.18 AET38176.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_M PF01031.15 AET38177.1 - 3.9e-103 344.3 0.1 1.2e-102 342.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 AET38177.1 - 6.3e-57 192.0 0.1 1.2e-56 191.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 AET38177.1 - 4.3e-26 90.6 3.0 4.3e-26 90.6 2.1 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AET38177.1 - 0.00055 19.8 0.2 0.014 15.3 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AET38177.1 - 0.038 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein HTH_9 PF08221.6 AET38177.1 - 0.11 12.3 0.1 0.45 10.4 0.1 2.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain AA_permease_2 PF13520.1 AET38178.1 - 1.5e-85 287.3 46.9 1.8e-85 287.0 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AET38178.1 - 9.6e-17 60.4 43.2 1.7e-16 59.6 30.0 1.3 1 1 0 1 1 1 1 Amino acid permease Bromodomain PF00439.20 AET38179.1 - 4e-31 106.7 2.7 9.4e-15 54.3 0.3 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 AET38179.1 - 7.4e-23 80.5 0.2 2e-22 79.1 0.2 1.8 1 0 0 1 1 1 1 BAH domain Lyase_1 PF00206.15 AET38180.1 - 2e-22 79.7 0.0 3.2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 AET38180.1 - 2.5e-17 62.6 0.2 1.3e-16 60.4 0.0 2.3 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus AsiA PF09010.5 AET38180.1 - 0.013 15.3 0.0 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 Anti-Sigma Factor A Folliculin PF11704.3 AET38181.1 - 3.6e-50 169.8 0.4 4.6e-50 169.4 0.3 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Metallophos PF00149.23 AET38182.1 - 3.9e-13 49.2 1.1 9.8e-13 47.9 0.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AET38182.1 - 0.00024 20.9 0.0 0.00047 20.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 AET38184.1 - 1.2e-66 224.5 0.0 2.5e-66 223.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38184.1 - 7.4e-49 166.1 0.1 6.3e-48 163.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 AET38184.1 - 5.8e-35 119.3 0.1 2.1e-34 117.5 0.1 2.0 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 AET38184.1 - 1.7e-10 40.5 0.2 7.2e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AET38184.1 - 8.1e-09 35.5 0.0 3.1e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 AET38184.1 - 9.8e-06 24.7 0.0 5e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like VPS11_C PF12451.3 AET38185.1 - 7.8e-11 41.6 0.1 7.8e-11 41.6 0.1 2.5 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.1 AET38185.1 - 1.1e-05 25.2 6.0 3.2e-05 23.8 4.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET38185.1 - 3e-05 23.7 5.2 3e-05 23.7 3.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 AET38185.1 - 0.00024 20.8 4.5 0.0018 18.0 3.3 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AET38185.1 - 0.00055 19.6 5.8 0.00055 19.6 4.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain PHD PF00628.24 AET38185.1 - 0.0087 15.7 4.6 0.0087 15.7 3.2 2.5 2 0 0 2 2 2 1 PHD-finger zf-Apc11 PF12861.2 AET38185.1 - 0.013 15.3 1.5 0.029 14.1 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AET38185.1 - 0.019 15.0 3.6 0.054 13.6 2.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 AET38185.1 - 0.037 13.7 2.5 0.13 11.9 1.8 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 AET38185.1 - 0.042 13.4 10.5 0.017 14.7 4.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 AET38185.1 - 0.099 12.4 1.6 0.26 11.1 1.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon RRS1 PF04939.7 AET38187.1 - 1.8e-64 216.1 4.3 2.1e-64 215.9 3.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Membr_traf_MHD PF10540.4 AET38188.1 - 2.8e-14 53.0 0.1 3e-13 49.7 0.0 2.7 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 AET38188.1 - 1.1e-11 44.3 0.4 5.9e-11 42.0 0.1 2.2 2 0 0 2 2 2 1 C2 domain DUF810 PF05664.6 AET38188.1 - 2.7e-06 26.0 0.1 7e-05 21.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF810) RNase_H PF00075.19 AET38189.1 - 9.6e-20 71.2 0.0 1.8e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 AET38189.1 - 3.6e-19 68.5 5.9 1e-12 47.8 1.2 2.8 3 0 0 3 3 3 2 Caulimovirus viroplasmin AMP-binding PF00501.23 AET38190.1 - 6.5e-73 245.5 0.1 1.1e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF1106 PF06523.6 AET38190.1 - 0.042 13.6 0.2 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Abhydrolase_6 PF12697.2 AET38191.1 - 1e-24 87.6 0.0 1.3e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET38191.1 - 1.1e-22 80.7 0.1 1.5e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AET38191.1 - 1.2e-08 34.8 0.0 4.6e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 AET38191.1 - 0.00073 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase zf-MYND PF01753.13 AET38192.1 - 1.1e-05 25.1 23.3 2.9e-05 23.8 16.1 1.7 1 1 0 1 1 1 1 MYND finger Vma12 PF11712.3 AET38193.1 - 1.1e-31 109.4 0.0 1.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2775 PF10950.3 AET38193.1 - 0.25 11.5 1.2 0.3 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2775) Prenyltransf PF01255.14 AET38194.1 - 6.4e-72 241.2 0.4 8.7e-72 240.8 0.3 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PRESAN PF09687.5 AET38194.1 - 0.71 9.9 3.2 0.43 10.6 0.1 2.2 3 0 0 3 3 3 0 Plasmodium RESA N-terminal Mito_carr PF00153.22 AET38195.1 - 2.4e-56 187.3 4.0 1.1e-19 69.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP9-21 PF05486.7 AET38196.1 - 5.1e-20 71.0 0.1 7.3e-20 70.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) SPRY PF00622.23 AET38197.1 - 2.5e-11 43.7 0.0 5.5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 SPRY domain RRN3 PF05327.6 AET38198.1 - 2.6e-181 603.5 11.1 4e-181 602.9 7.7 1.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 F1F0-ATPsyn_F PF10791.4 AET38198.1 - 0.0078 16.4 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Exonuc_VII_L PF02601.10 AET38198.1 - 0.037 13.2 0.1 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PGM_PMM_I PF02878.11 AET38199.1 - 8.6e-33 112.7 0.1 1.3e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 AET38199.1 - 1.7e-24 86.0 0.0 3.8e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 AET38199.1 - 6.8e-12 45.6 0.0 1.8e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AET38199.1 - 1.5e-08 34.5 0.0 4.2e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ku PF02735.11 AET38200.1 - 2.6e-34 118.3 0.1 4.5e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 AET38200.1 - 7.9e-11 41.8 0.6 1.5e-10 40.8 0.4 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain CLASP_N PF12348.3 AET38201.1 - 8.2e-08 31.8 0.1 2.3e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 CLASP N terminal DUF641 PF04859.7 AET38201.1 - 0.00027 20.6 4.6 0.00027 20.6 3.2 2.0 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) HEAT_2 PF13646.1 AET38201.1 - 0.0032 17.7 0.1 0.7 10.2 0.0 3.9 2 2 2 5 5 5 1 HEAT repeats Myosin_tail_1 PF01576.14 AET38201.1 - 0.0035 15.1 9.4 0.0077 14.0 6.5 1.5 1 0 0 1 1 1 1 Myosin tail HEAT PF02985.17 AET38201.1 - 0.0036 17.2 0.0 1.6 9.0 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat PIN_4 PF13638.1 AET38201.1 - 0.005 16.9 1.5 0.017 15.1 1.0 1.9 1 0 0 1 1 1 1 PIN domain DUF1411 PF07199.6 AET38201.1 - 0.006 16.0 0.3 0.013 14.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1411) IncA PF04156.9 AET38201.1 - 0.016 14.8 4.6 0.05 13.1 3.2 1.8 1 0 0 1 1 1 0 IncA protein DUF3209 PF11483.3 AET38201.1 - 0.075 13.3 0.2 19 5.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3209) APG6 PF04111.7 AET38201.1 - 0.32 9.9 12.0 0.065 12.2 5.0 2.2 3 0 0 3 3 3 0 Autophagy protein Apg6 Cortex-I_coil PF09304.5 AET38201.1 - 0.34 10.9 9.7 2.1 8.4 6.7 2.3 1 1 0 1 1 1 0 Cortexillin I, coiled coil CENP-F_leu_zip PF10473.4 AET38201.1 - 0.51 10.1 13.8 6.6 6.5 0.1 3.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 AET38201.1 - 0.77 10.0 11.2 0.024 14.9 2.2 2.6 3 0 0 3 3 3 0 Striatin family Tropomyosin_1 PF12718.2 AET38201.1 - 6.3 6.6 14.9 2 8.2 7.4 2.2 2 0 0 2 2 2 0 Tropomyosin like TPP_enzyme_M PF00205.17 AET38202.1 - 2.3e-35 121.2 0.0 1.1e-34 119.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 AET38202.1 - 8.3e-35 119.7 0.1 1.3e-34 119.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AET38202.1 - 5.8e-15 55.1 0.0 1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain APC_15aa PF05972.6 AET38202.1 - 0.18 11.8 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 APC 15 residue motif AA_permease PF00324.16 AET38203.1 - 7.8e-118 393.8 38.7 9.8e-118 393.5 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET38203.1 - 1.2e-30 106.4 40.3 1.7e-30 105.8 27.9 1.3 1 0 0 1 1 1 1 Amino acid permease MMR_HSR1_C PF08438.5 AET38204.1 - 1.7e-30 105.4 0.0 2.8e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AET38204.1 - 1.8e-18 66.5 0.0 3.8e-18 65.5 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AET38204.1 - 7.2e-07 28.6 0.1 1.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AET38204.1 - 0.00011 21.6 0.1 0.086 12.2 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AET38204.1 - 0.0065 16.3 0.4 0.093 12.5 0.1 2.6 3 0 0 3 3 3 1 Dynamin family ATP_bind_1 PF03029.12 AET38204.1 - 0.046 13.2 0.2 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 AET38204.1 - 0.051 13.8 0.0 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 AET38204.1 - 0.051 13.0 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 AET38204.1 - 0.19 10.4 0.3 0.46 9.2 0.0 1.7 2 0 0 2 2 2 0 ArgK protein zf-ZPR1 PF03367.8 AET38205.1 - 4.9e-115 380.1 4.1 1e-59 200.3 0.1 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain UPF0547 PF10571.4 AET38205.1 - 0.022 14.4 2.2 0.6 9.8 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF4435 PF14491.1 AET38205.1 - 0.023 14.5 0.2 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4435) HypA PF01155.14 AET38205.1 - 0.05 13.2 3.6 3.1 7.5 0.4 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DnaJ_CXXCXGXG PF00684.14 AET38205.1 - 0.41 10.7 0.1 0.41 10.7 0.1 3.1 2 1 0 2 2 2 0 DnaJ central domain zinc_ribbon_5 PF13719.1 AET38205.1 - 0.44 10.1 5.0 9.3 5.9 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AET38205.1 - 0.55 9.9 5.3 12 5.7 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain AATase PF07247.7 AET38206.1 - 1.6e-51 175.3 0.0 2.1e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 AET38206.1 - 1.6e-07 30.4 0.0 1.1e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Condensation domain Transferase PF02458.10 AET38206.1 - 0.0071 14.8 0.0 0.026 12.9 0.0 1.8 1 1 0 1 1 1 1 Transferase family LicD PF04991.8 AET38207.1 - 1.3e-21 77.6 0.3 1.3e-21 77.6 0.2 3.0 3 0 0 3 3 3 1 LicD family Ferric_reduct PF01794.14 AET38208.1 - 2.7e-16 59.8 13.7 2.7e-16 59.8 9.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 AET38208.1 - 0.00018 21.3 0.1 0.00043 20.1 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain Ytp1 PF10355.4 AET38209.1 - 5e-109 363.6 10.6 5.5e-109 363.5 6.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 AET38209.1 - 5.2e-23 80.6 5.9 5.2e-23 80.6 4.1 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) G10 PF01125.12 AET38210.1 - 4e-54 182.1 4.2 4.7e-54 181.8 2.9 1.1 1 0 0 1 1 1 1 G10 protein Fork_head PF00250.13 AET38211.1 - 1.1e-33 115.0 0.0 9e-33 112.1 0.0 2.1 2 0 0 2 2 2 1 Fork head domain zf-C3HC4 PF00097.20 AET38212.1 - 3.7e-09 36.0 15.3 1.1e-08 34.5 7.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET38212.1 - 9.8e-09 35.1 16.3 2e-08 34.0 7.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 AET38212.1 - 2.6e-08 33.1 0.0 5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.1 AET38212.1 - 1.3e-07 31.1 12.3 2.1e-06 27.2 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AET38212.1 - 2.8e-07 30.3 12.6 1e-06 28.5 7.0 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 AET38212.1 - 9.3e-07 28.5 4.5 9.3e-07 28.5 3.1 2.8 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 AET38212.1 - 1.2e-06 28.1 14.1 1.1e-05 25.0 7.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 AET38212.1 - 2.2e-06 27.3 14.9 2.7e-05 23.9 7.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 AET38212.1 - 5e-05 23.3 10.7 7.7e-05 22.7 2.8 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 AET38212.1 - 0.00011 21.8 11.8 0.00011 21.7 4.9 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 AET38212.1 - 0.022 14.2 9.4 0.1 12.1 3.2 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 AET38212.1 - 0.025 14.5 0.0 0.74 9.8 0.0 2.7 2 0 0 2 2 2 0 U-box domain zf-C2HC_2 PF13913.1 AET38212.1 - 0.069 12.8 0.2 0.069 12.8 0.2 3.6 5 0 0 5 5 4 0 zinc-finger of a C2HC-type zf-Apc11 PF12861.2 AET38212.1 - 0.071 12.9 4.4 0.1 12.4 1.9 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4513 PF14983.1 AET38212.1 - 0.081 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4513) zf-FCS PF06467.9 AET38212.1 - 0.17 11.5 4.0 0.32 10.6 1.0 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 AET38212.1 - 0.27 11.4 5.6 1.3 9.1 0.1 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 AET38212.1 - 0.29 11.0 4.8 16 5.5 0.0 3.6 3 0 0 3 3 3 0 Zinc ribbon domain zf-RING_4 PF14570.1 AET38212.1 - 0.35 10.4 10.6 0.92 9.1 4.7 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-AN1 PF01428.11 AET38212.1 - 0.77 9.6 6.9 6.9 6.6 1.8 2.7 2 0 0 2 2 2 0 AN1-like Zinc finger PRESAN PF09687.5 AET38212.1 - 1 9.4 8.3 2.1 8.3 5.7 1.5 1 0 0 1 1 1 0 Plasmodium RESA N-terminal zf-MIZ PF02891.15 AET38212.1 - 2.6 7.6 11.7 19 4.8 0.0 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger FYVE PF01363.16 AET38212.1 - 6.8 6.6 12.0 6.7 6.6 0.2 2.8 2 1 0 2 2 2 0 FYVE zinc finger WD40 PF00400.27 AET38213.1 - 1.5e-08 34.1 0.0 0.00021 21.0 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Phos_pyr_kin PF08543.7 AET38214.1 - 3.8e-13 49.2 0.0 5.1e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 AET38214.1 - 2e-06 27.1 0.0 8.1e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Lipase_3 PF01764.20 AET38215.1 - 1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 AET38215.1 - 0.046 13.4 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Herpes_capsid PF06112.6 AET38215.1 - 0.5 10.4 3.5 1.4 8.9 2.4 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pro_isomerase PF00160.16 AET38216.1 - 3.9e-29 101.8 0.2 6e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD cobW PF02492.14 AET38217.1 - 5.6e-42 143.1 0.1 8.5e-42 142.5 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 AET38217.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.1 AET38217.1 - 0.0018 17.7 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 AET38217.1 - 0.0038 17.2 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 AET38217.1 - 0.0059 16.3 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 AET38217.1 - 0.0074 16.5 0.4 0.025 14.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AET38217.1 - 0.0091 15.7 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 AET38217.1 - 0.014 15.3 0.0 0.04 13.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AET38217.1 - 0.014 14.8 0.0 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 AET38217.1 - 0.014 15.7 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AET38217.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 AET38217.1 - 0.072 13.2 0.1 0.25 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 AET38217.1 - 0.073 11.9 0.1 0.15 10.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 AET38217.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 AET38217.1 - 0.15 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Glyco_transf_22 PF03901.12 AET38218.1 - 1.3e-30 106.7 22.8 2.1e-30 106.1 15.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Img2 PF05046.9 AET38219.1 - 3.9e-22 78.2 0.0 5.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) WD40 PF00400.27 AET38220.1 - 8.1e-85 275.9 36.2 2e-15 55.9 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 AET38220.1 - 1.7e-08 34.4 1.2 0.00067 19.4 0.0 3.8 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 AET38220.1 - 3.2e-07 30.2 0.1 5.9e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 AET38220.1 - 1.8e-06 26.3 11.1 0.14 10.2 0.5 5.5 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AET38220.1 - 0.00011 21.0 5.7 0.12 11.1 2.1 3.9 2 1 0 2 2 2 2 Nup133 N terminal like Nbas_N PF15492.1 AET38220.1 - 0.0055 15.8 3.0 0.67 8.9 0.1 3.3 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 AET38220.1 - 0.0098 14.2 0.1 0.22 9.7 0.1 2.7 2 1 1 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 AET38220.1 - 0.019 14.6 0.2 2.7 7.7 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 AET38220.1 - 0.068 13.4 0.3 17 5.8 0.0 3.0 2 0 0 2 2 2 0 PQQ-like domain Imm38 PF15599.1 AET38220.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 38 Pkinase PF00069.20 AET38221.1 - 2.9e-64 216.7 0.0 8.1e-64 215.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38221.1 - 3.4e-35 121.3 0.0 6.7e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38221.1 - 0.00056 18.9 0.0 0.0016 17.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Metallophos PF00149.23 AET38222.1 - 6.7e-41 139.8 0.4 1.1e-40 139.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AET38222.1 - 0.0032 17.3 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ubiquitin PF00240.18 AET38223.1 - 5.3e-07 28.9 0.3 6.4e-07 28.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AET38223.1 - 1.5e-05 24.5 0.1 1.6e-05 24.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AET38223.1 - 0.005 17.0 0.3 0.026 14.7 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Plexin_cytopl PF08337.7 AET38223.1 - 0.017 13.4 0.2 2.7 6.1 0.0 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Chorismate_bind PF00425.13 AET38224.1 - 9.3e-64 215.2 0.0 1.5e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 AET38224.1 - 8.8e-34 116.6 0.0 2.4e-33 115.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 AET38224.1 - 1.7e-14 54.0 0.0 3.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 AET38224.1 - 1.8e-08 34.1 0.0 3.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 ApoLp-III PF07464.6 AET38224.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Glucosamine_iso PF01182.15 AET38225.1 - 8.9e-48 162.6 0.0 2.1e-47 161.4 0.0 1.5 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase BCDHK_Adom3 PF10436.4 AET38226.1 - 1.5e-59 200.1 0.0 2.9e-59 199.2 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AET38226.1 - 2.9e-16 59.1 0.0 5.9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AET38226.1 - 0.0074 15.9 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Imm23 PF15593.1 AET38226.1 - 0.057 13.6 0.2 0.15 12.2 0.1 1.8 1 1 0 1 1 1 0 Immunity protein 23 LMBR1 PF04791.11 AET38227.1 - 4e-10 38.8 21.7 5.3e-09 35.1 15.0 2.1 1 1 0 1 1 1 1 LMBR1-like membrane protein Fb_signal PF08341.6 AET38227.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Fibronectin-binding protein signal sequence DUF3671 PF12420.3 AET38227.1 - 0.043 13.7 0.8 0.043 13.7 0.6 4.2 4 1 1 5 5 5 0 Protein of unknown function DUF2871 PF11070.3 AET38227.1 - 0.061 13.4 0.5 0.061 13.4 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2871) DUF3215 PF11503.3 AET38228.1 - 1.7e-26 91.6 0.2 1.8e-26 91.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) Nucleoporin2 PF04096.9 AET38228.1 - 0.1 12.3 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin autopeptidase PI31_Prot_C PF08577.6 AET38229.1 - 5e-10 39.8 10.4 1.4e-09 38.4 7.2 1.8 1 0 0 1 1 1 1 PI31 proteasome regulator PAT1 PF09770.4 AET38230.1 - 1.9e-249 830.1 42.8 3.2e-249 829.4 29.7 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 P34-Arc PF04045.9 AET38231.1 - 2.5e-92 308.5 0.3 3.3e-92 308.1 0.2 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Ribosom_S12_S23 PF00164.20 AET38232.1 - 5.9e-44 148.3 1.7 7.2e-44 148.1 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PP2C PF00481.16 AET38233.1 - 6.9e-30 104.2 0.0 1.2e-25 90.3 0.0 2.7 1 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 AET38233.1 - 0.03 13.7 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C Ribosomal_S19 PF00203.16 AET38234.1 - 1.8e-22 78.7 0.0 2.2e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.24 AET38235.1 - 8.7e-38 129.4 0.6 1.7e-37 128.5 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET38235.1 - 5.3e-18 64.6 0.8 1.2e-17 63.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET38235.1 - 6.1e-07 29.4 3.3 6.5e-07 29.3 0.1 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 AET38235.1 - 0.0012 18.6 0.5 0.0039 16.9 0.1 2.2 2 1 0 2 2 2 1 Flavivirus DEAD domain Phage_portal_2 PF05136.8 AET38235.1 - 0.046 12.2 1.3 0.08 11.4 0.9 1.3 1 0 0 1 1 1 0 Phage portal protein, lambda family AAA_22 PF13401.1 AET38235.1 - 1 9.5 4.0 7.3 6.7 1.4 3.3 2 1 0 2 2 2 0 AAA domain Med12 PF09497.5 AET38236.1 - 2e-25 88.5 0.1 6.4e-25 86.9 0.1 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Cation_efflux PF01545.16 AET38237.1 - 7.6e-08 31.7 8.8 3.4e-07 29.6 5.5 2.1 2 1 0 2 2 2 1 Cation efflux family Thioredoxin PF00085.15 AET38239.1 - 1.8e-29 101.4 0.0 2.2e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AET38239.1 - 2.7e-09 37.0 0.4 5.6e-07 29.6 0.1 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AET38239.1 - 9.3e-08 32.2 0.2 6.3e-07 29.5 0.1 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AET38239.1 - 1.7e-06 27.6 0.0 2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 AET38239.1 - 3.2e-05 23.6 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 AET38239.1 - 4.1e-05 23.5 0.1 9e-05 22.4 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 AET38239.1 - 0.00036 20.1 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.1 AET38239.1 - 0.0074 15.7 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein KaiB PF07689.7 AET38239.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 KaiB domain HyaE PF07449.6 AET38239.1 - 0.024 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF2847 PF11009.3 AET38239.1 - 0.07 12.7 0.1 0.36 10.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2847) DUF3995 PF13160.1 AET38240.1 - 0.087 12.8 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) UbiA PF01040.13 AET38241.1 - 2.2e-33 115.5 17.6 2.8e-33 115.2 12.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GHMP_kinases_N PF00288.21 AET38242.1 - 5.6e-12 45.5 0.6 1.2e-11 44.4 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Zn_clus PF00172.13 AET38243.1 - 1.8e-08 34.1 9.0 1.8e-08 34.1 6.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 AET38244.1 - 3.4e-63 207.4 15.1 6.6e-10 38.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 AET38244.1 - 1.9e-31 108.1 13.7 3e-31 107.4 9.5 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 AET38244.1 - 6.4e-06 24.5 3.2 0.14 10.2 0.1 4.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AET38244.1 - 4.5e-05 22.3 2.1 0.009 14.7 0.3 3.4 1 1 2 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 AET38244.1 - 0.0083 14.4 1.0 3.5 5.8 0.0 2.9 2 1 0 3 3 3 2 Cytochrome D1 heme domain Ribosomal_60s PF00428.14 AET38244.1 - 0.0093 16.3 3.5 0.03 14.7 2.4 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein NIT PF08376.5 AET38244.1 - 0.028 13.9 5.1 0.041 13.3 3.5 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing FimP PF09766.4 AET38244.1 - 0.15 11.0 7.6 0.23 10.4 5.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein UPF0016 PF01169.14 AET38244.1 - 0.42 10.7 3.3 0.88 9.7 2.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 TSA PF03249.8 AET38244.1 - 1.1 7.7 7.0 4.2 5.7 4.9 1.8 1 1 0 1 1 1 0 Type specific antigen SBP_bac_7 PF03480.8 AET38244.1 - 2.8 6.9 6.2 1.4 7.9 2.7 1.7 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Csm1 PF12539.3 AET38245.1 - 1.2e-32 112.1 0.3 2.7e-32 111.0 0.0 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Complex1_49kDa PF00346.14 AET38245.1 - 0.00025 20.1 0.0 0.0006 18.8 0.0 1.5 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Lebercilin PF15619.1 AET38245.1 - 0.003 16.9 4.5 0.0055 16.1 3.1 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease GRIM-19 PF06212.7 AET38245.1 - 0.0048 16.6 0.5 0.0086 15.7 0.2 1.5 2 0 0 2 2 2 1 GRIM-19 protein CENP-Q PF13094.1 AET38245.1 - 0.018 15.0 4.6 0.034 14.1 3.2 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HTH_39 PF14090.1 AET38245.1 - 0.058 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain IncA PF04156.9 AET38245.1 - 0.065 12.8 6.3 0.11 12.0 4.4 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 AET38245.1 - 0.1 10.4 1.5 0.11 10.3 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 AET38245.1 - 0.13 11.3 5.1 0.18 10.8 3.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 AET38245.1 - 0.15 12.3 3.1 0.29 11.5 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 AET38245.1 - 0.23 11.3 10.0 0.065 13.0 4.9 1.7 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 AET38245.1 - 0.26 10.1 3.8 0.35 9.7 2.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 AET38245.1 - 0.7 9.6 4.5 0.9 9.2 2.7 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 TSC22 PF01166.13 AET38245.1 - 1 9.3 6.2 5.9 6.9 2.5 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF16 PF01519.11 AET38245.1 - 1.5 9.0 5.7 2.2 8.5 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF904 PF06005.7 AET38245.1 - 2.6 8.3 9.2 3 8.2 5.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) SlyX PF04102.7 AET38245.1 - 4.9 7.5 7.2 16 5.9 5.0 2.0 1 1 0 1 1 1 0 SlyX zf-LYAR PF08790.6 AET38246.1 - 2.5e-14 52.6 5.5 5.1e-14 51.6 3.8 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-met PF12874.2 AET38246.1 - 0.0083 16.3 2.2 1.2 9.4 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_2 PF03107.11 AET38246.1 - 0.035 14.2 7.3 0.15 12.2 1.9 2.3 2 0 0 2 2 2 0 C1 domain DUF4352 PF11611.3 AET38246.1 - 0.051 13.7 1.7 0.077 13.1 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) UPF0223 PF05256.7 AET38246.1 - 0.083 13.0 1.2 0.28 11.3 0.3 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0223) A2L_zn_ribbon PF08792.5 AET38246.1 - 0.088 12.2 5.2 0.17 11.4 0.6 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2_6 PF13912.1 AET38246.1 - 2.2 8.3 4.3 10 6.1 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger RNHCP PF12647.2 AET38246.1 - 2.6 7.9 5.3 0.91 9.3 0.6 2.1 1 1 1 2 2 2 0 RNHCP domain Cofilin_ADF PF00241.15 AET38247.1 - 2.6e-20 72.5 0.0 5.8e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 AET38247.1 - 2.4e-17 62.0 0.8 6.7e-17 60.6 0.5 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AET38247.1 - 4.3e-16 58.2 0.4 9.5e-16 57.1 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AET38247.1 - 1.6e-07 30.7 0.0 2.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF866 PF05907.8 AET38248.1 - 5.4e-25 87.7 7.1 6.3e-17 61.5 1.1 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) Fer4_8 PF13183.1 AET38248.1 - 0.27 11.2 3.0 0.28 11.2 0.4 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-BED PF02892.10 AET38248.1 - 4.4 7.1 5.5 6.8 6.5 1.9 2.4 1 1 1 2 2 2 0 BED zinc finger SUV3_C PF12513.3 AET38250.1 - 4.5e-13 48.4 2.2 1.1e-12 47.1 1.5 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 AET38250.1 - 5.7e-11 42.1 0.0 1.3e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AET38250.1 - 0.00098 18.6 0.0 0.0054 16.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AdoMet_MTase PF07757.8 AET38251.1 - 9.2e-43 144.9 0.4 1.7e-42 144.0 0.3 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 AET38251.1 - 0.018 14.6 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 AET38251.1 - 0.031 13.8 0.2 0.098 12.2 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AET38251.1 - 0.08 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 AET38251.1 - 0.086 13.4 0.0 0.36 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.20 AET38252.1 - 2.1e-73 246.6 0.0 2.4e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38252.1 - 5.1e-36 124.0 0.0 7.1e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38252.1 - 0.00013 21.0 0.1 0.00019 20.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AET38252.1 - 0.0056 16.4 0.0 0.052 13.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family F-box-like_2 PF13013.1 AET38253.1 - 0.018 14.7 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain DivIC PF04977.10 AET38254.1 - 0.00035 19.9 6.5 0.022 14.2 1.1 2.4 2 0 0 2 2 2 2 Septum formation initiator ApbA_C PF08546.6 AET38254.1 - 0.00039 20.4 0.0 0.00074 19.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF390 PF04094.9 AET38254.1 - 0.15 10.0 0.6 0.24 9.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF972 PF06156.8 AET38254.1 - 0.21 11.9 7.2 1.9 8.8 0.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 AET38254.1 - 0.37 10.4 5.8 0.64 9.6 4.0 1.3 1 0 0 1 1 1 0 Mnd1 family DUF904 PF06005.7 AET38254.1 - 0.88 9.9 7.6 0.16 12.2 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 AET38254.1 - 3.9 7.0 5.8 6.9 6.2 4.0 1.3 1 0 0 1 1 1 0 IncA protein NAC PF01849.13 AET38255.1 - 1.7e-16 59.4 0.1 3.1e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 NAC domain Glyco_hydro_20b PF02838.10 AET38255.1 - 0.035 14.6 0.0 0.045 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 zf-C2H2_4 PF13894.1 AET38256.1 - 4.3e-10 39.1 4.1 0.00055 20.0 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AET38256.1 - 7.4e-08 32.2 9.2 0.0024 18.1 1.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET38256.1 - 0.0017 18.5 7.9 0.19 12.0 0.4 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 AET38256.1 - 0.0039 17.3 0.5 0.19 11.9 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AET38256.1 - 0.021 14.9 3.0 0.04 14.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 AET38256.1 - 0.7 10.2 5.3 0.32 11.2 0.4 2.5 2 1 0 2 2 2 0 C2H2-type zinc-finger domain tRNA-synt_1 PF00133.17 AET38258.1 - 2.3e-150 501.4 0.0 1.1e-149 499.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AET38258.1 - 8.7e-22 77.5 0.4 2.6e-21 75.9 0.2 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AET38258.1 - 1.3e-19 70.1 0.1 8.8e-11 41.0 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 AET38258.1 - 0.00011 21.7 2.6 0.00027 20.5 1.8 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Asp_protease_2 PF13650.1 AET38258.1 - 0.0089 16.5 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease FLILHELTA PF10306.4 AET38259.1 - 1.2e-20 73.2 0.0 3e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 AET38259.1 - 0.0029 17.8 0.4 0.0054 17.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) Pkinase PF00069.20 AET38260.1 - 1.3e-55 188.3 0.0 7.7e-54 182.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AET38260.1 - 1e-27 96.8 0.0 4.3e-26 91.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RRM_1 PF00076.17 AET38261.1 - 5.7e-54 179.6 0.3 4.7e-16 58.1 0.1 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET38261.1 - 2.4e-46 155.5 0.2 3.9e-13 49.1 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET38261.1 - 1.2e-20 73.0 1.1 5.7e-09 35.7 0.0 5.8 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 AET38261.1 - 0.18 11.3 2.5 10 5.7 0.1 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain Trypan_PARP PF05887.6 AET38261.1 - 8.3 6.2 16.6 0.13 12.0 2.4 2.7 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) CENP-N PF05238.8 AET38262.1 - 1.8e-74 251.2 0.0 4.1e-74 250.0 0.0 1.5 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Vps16_C PF04840.7 AET38263.1 - 4.1e-75 252.6 11.1 6.5e-75 252.0 7.7 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 AET38263.1 - 1.3e-59 201.8 1.0 2.2e-59 201.0 0.7 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region DUF4283 PF14111.1 AET38263.1 - 0.075 12.1 0.1 0.42 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) Skp1_POZ PF03931.10 AET38264.1 - 5.8e-15 55.1 0.4 8.5e-15 54.6 0.1 1.4 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 AET38264.1 - 0.044 13.7 0.5 0.11 12.5 0.4 1.7 1 1 0 1 1 1 0 BTB/POZ domain Spore_YhaL PF14147.1 AET38264.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL HLH PF00010.21 AET38264.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain zf-RING_UBOX PF13445.1 AET38265.1 - 1.6e-13 50.1 4.6 6.6e-13 48.1 3.2 2.2 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 AET38265.1 - 8.2e-10 38.5 6.6 3.1e-09 36.6 1.7 2.7 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 AET38265.1 - 0.0073 16.1 2.7 0.021 14.6 1.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AET38265.1 - 4.7 7.0 8.7 0.44 10.3 2.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Sgf11 PF08209.6 AET38266.1 - 8.5e-17 60.1 3.1 1.2e-16 59.6 2.1 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Catalase PF00199.14 AET38267.1 - 6.7e-171 568.1 0.5 8.4e-171 567.8 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 AET38267.1 - 1.8e-12 46.9 0.2 7.1e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive GST_C PF00043.20 AET38268.1 - 3.6e-11 42.9 0.2 5.4e-11 42.3 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AET38268.1 - 6.7e-07 29.3 0.0 3e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AET38268.1 - 3.7e-05 23.5 0.3 8e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AET38268.1 - 0.049 14.1 0.2 0.089 13.2 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Anp1 PF03452.9 AET38270.1 - 3.9e-105 350.8 0.1 4.7e-105 350.5 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 AET38270.1 - 0.015 15.0 0.4 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 Alk_phosphatase PF00245.15 AET38271.1 - 2.6e-109 365.7 0.1 3.1e-109 365.4 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 AET38271.1 - 0.0013 18.1 0.2 0.0032 16.8 0.2 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 AET38271.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Metalloenzyme superfamily Arf PF00025.16 AET38272.1 - 5.2e-46 156.0 0.1 7.1e-46 155.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AET38272.1 - 6.1e-13 48.4 0.0 7.2e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET38272.1 - 3.1e-12 47.0 0.0 4.4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 AET38272.1 - 2.3e-11 43.2 0.0 2.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 AET38272.1 - 4.5e-10 38.7 0.4 0.00012 20.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 AET38272.1 - 4e-07 29.6 0.0 1.2e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AET38272.1 - 4.5e-06 25.9 0.1 5.5e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AET38272.1 - 4.9e-05 23.2 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AET38272.1 - 0.02 15.0 0.0 0.061 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AET38272.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AET38272.1 - 0.14 11.8 0.1 0.45 10.1 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase Caprin-1_C PF12287.3 AET38273.1 - 3.5 6.9 5.9 2 7.7 2.4 1.6 1 1 1 2 2 2 0 Cytoplasmic activation/proliferation-associated protein-1 C term cwf21 PF08312.7 AET38274.1 - 6.6e-12 45.0 8.5 1.2e-11 44.2 5.9 1.5 1 0 0 1 1 1 1 cwf21 domain DUF4404 PF14357.1 AET38274.1 - 0.26 11.7 4.2 0.24 11.8 1.5 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) ODC_AZ PF02100.12 AET38275.1 - 7.4e-08 31.8 0.0 1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme MIP PF00230.15 AET38276.1 - 1e-44 152.6 14.4 1.2e-44 152.4 10.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4271 PF14093.1 AET38276.1 - 0.057 13.0 0.5 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Glyco_transf_15 PF01793.11 AET38277.1 - 4e-146 486.1 11.4 4.8e-146 485.9 7.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Rubis-subs-bind PF09273.6 AET38277.1 - 0.046 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding TPR_11 PF13414.1 AET38278.1 - 5.2e-16 58.0 2.9 2.7e-12 46.1 0.6 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AET38278.1 - 1.8e-11 43.1 8.5 0.00036 20.0 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AET38278.1 - 1.2e-08 34.1 4.5 0.012 15.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AET38278.1 - 7.5e-06 25.8 0.9 0.011 15.6 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AET38278.1 - 7.9e-05 22.7 3.9 0.00023 21.2 2.5 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 AET38278.1 - 0.0025 18.4 0.0 1.4 9.6 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AET38278.1 - 0.0048 16.5 1.4 0.35 10.7 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 AET38278.1 - 0.019 15.3 0.3 0.38 11.1 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AET38278.1 - 0.065 13.7 1.6 0.21 12.1 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 AET38278.1 - 0.11 12.7 0.5 0.77 10.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AET38278.1 - 0.33 10.8 2.4 4.2 7.3 0.1 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat INCENP_ARK-bind PF03941.10 AET38279.1 - 2.7e-20 71.9 1.2 6.6e-20 70.7 0.8 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Tox-REase-3 PF15647.1 AET38279.1 - 0.021 14.6 2.2 0.052 13.3 0.2 2.7 3 1 1 4 4 4 0 Restriction endonuclease fold toxin 3 zf-CCCH PF00642.19 AET38281.1 - 3e-10 39.5 12.3 5.7e-06 25.8 2.0 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AET38281.1 - 0.089 12.8 13.3 0.72 9.9 2.5 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Lge1 PF11488.3 AET38282.1 - 7.5e-16 58.0 5.2 7.5e-16 58.0 3.6 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 BAF1_ABF1 PF04684.8 AET38282.1 - 0.56 9.0 17.1 0.86 8.3 11.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor adh_short PF00106.20 AET38283.1 - 3.7e-23 82.2 0.0 6.4e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AET38283.1 - 3.1e-09 36.9 0.1 4.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AET38283.1 - 1.7e-07 31.1 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 AET38283.1 - 0.0012 17.8 0.5 0.0016 17.3 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AET38283.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 AET38283.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 AET38283.1 - 0.096 12.1 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 AET38284.1 - 2.8e-74 249.5 0.0 3.2e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38284.1 - 5.5e-35 120.6 0.0 6.9e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38284.1 - 3.3e-07 29.5 0.0 7.4e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AET38284.1 - 0.0064 16.2 0.3 0.05 13.3 0.1 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AET38284.1 - 0.014 14.5 0.1 0.086 11.9 0.1 2.2 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AET38284.1 - 0.096 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2401 PF10287.4 AET38285.1 - 2.3e-97 325.1 5.6 2.7e-97 324.8 1.4 2.2 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 AET38285.1 - 2.6e-30 104.3 0.1 8.5e-30 102.7 0.1 2.0 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) GATA PF00320.22 AET38286.1 - 5.1e-16 57.7 3.8 1.1e-15 56.6 2.6 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 AET38286.1 - 0.13 11.5 0.6 0.25 10.6 0.4 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding XPG_I PF00867.13 AET38287.1 - 8.5e-22 77.0 0.0 3.5e-21 75.0 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.2 AET38287.1 - 4.4e-05 23.1 0.2 9.6e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 AET38287.1 - 0.023 14.9 0.0 0.071 13.3 0.0 1.9 1 0 0 1 1 1 0 XPG N-terminal domain PMSR PF01625.16 AET38288.1 - 2.8e-49 166.9 0.5 3.8e-49 166.5 0.3 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase COX4 PF02936.9 AET38289.1 - 3.8e-11 42.8 0.1 4.6e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Pox_A9 PF04835.7 AET38289.1 - 0.005 16.7 0.2 0.0077 16.1 0.1 1.2 1 0 0 1 1 1 1 A9 protein conserved region SPRY PF00622.23 AET38290.1 - 2.1e-22 79.5 0.1 3.9e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 AET38290.1 - 1.2e-12 47.6 2.4 2.1e-12 46.9 1.7 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 AET38290.1 - 0.03 14.0 0.0 0.091 12.5 0.0 1.9 1 0 0 1 1 1 0 LisH AdoHcyase PF05221.12 AET38291.1 - 3.5e-141 468.8 0.1 4.1e-141 468.6 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 AET38291.1 - 3.5e-86 287.0 2.2 5.7e-86 286.3 1.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 AET38291.1 - 3.3e-08 32.8 0.1 1e-07 31.3 0.0 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AET38291.1 - 0.00045 19.6 0.1 0.00074 18.9 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 AET38291.1 - 0.0037 17.2 0.1 0.0086 16.0 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 AET38291.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 AET38291.1 - 0.031 14.4 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein AlaDh_PNT_C PF01262.16 AET38291.1 - 0.088 12.3 0.5 0.18 11.3 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PuR_N PF09182.5 AET38292.1 - 0.039 13.5 0.7 0.48 10.0 0.1 2.8 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal PRANC PF09372.5 AET38292.1 - 0.12 12.3 2.0 0.64 10.0 0.1 2.7 2 1 0 2 2 2 0 PRANC domain SAPS PF04499.10 AET38293.1 - 7.4e-158 526.0 8.4 7.4e-158 526.0 5.8 2.3 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Myc_N PF01056.13 AET38293.1 - 0.7 8.9 13.7 0.016 14.3 0.8 3.1 3 0 0 3 3 3 0 Myc amino-terminal region DnaJ PF00226.26 AET38294.1 - 5.2e-14 51.7 3.0 4.2e-13 48.8 2.5 2.1 2 0 0 2 2 2 1 DnaJ domain Innexin PF00876.13 AET38294.1 - 0.0019 17.3 0.1 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Innexin DUF4131 PF13567.1 AET38294.1 - 0.064 12.6 0.0 0.71 9.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NOPS PF08075.6 AET38294.1 - 0.33 11.3 0.2 0.33 11.3 0.1 2.2 2 0 0 2 2 2 0 NOPS (NUC059) domain DUF1702 PF08012.6 AET38295.1 - 0.076 11.6 0.3 0.11 11.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) Adaptin_binding PF10199.4 AET38296.1 - 8.6e-06 26.0 3.0 0.048 13.9 0.3 2.5 1 1 1 2 2 2 2 Alpha and gamma adaptin binding protein p34 Ku_N PF03731.10 AET38296.1 - 0.0017 17.7 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain DUF1077 PF06417.7 AET38297.1 - 1.6e-47 159.9 3.7 2e-47 159.6 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Orbi_VP6 PF01516.11 AET38297.1 - 0.0071 15.4 0.0 0.0096 15.0 0.0 1.1 1 0 0 1 1 1 1 Orbivirus helicase VP6 PsbX PF06596.6 AET38297.1 - 0.19 11.4 0.3 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) THUMP PF02926.12 AET38298.1 - 7.8e-21 74.4 1.1 4e-20 72.1 0.1 2.1 1 1 1 2 2 2 1 THUMP domain MbeB_N PF04837.7 AET38298.1 - 0.061 13.4 1.4 0.21 11.6 1.0 1.9 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Phage_Gp14 PF10666.4 AET38298.1 - 4.9 7.0 9.1 0.22 11.3 0.6 2.5 2 1 0 2 2 2 0 Phage protein Gp14 Sec15 PF04091.7 AET38299.1 - 4.1e-107 358.0 12.9 4.1e-107 358.0 9.0 3.6 4 0 0 4 4 4 1 Exocyst complex subunit Sec15-like Mito_carr PF00153.22 AET38300.1 - 1.3e-41 140.2 5.5 1.7e-19 69.2 0.1 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein Toxin_47 PF15527.1 AET38300.1 - 0.12 12.1 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Putative toxin 47 GARS_A PF01071.14 AET38301.1 - 1.9e-80 268.9 0.0 3.3e-80 268.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 AET38301.1 - 7.7e-32 109.7 0.1 6.2e-31 106.8 0.0 2.6 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 AET38301.1 - 1e-31 110.0 0.0 5.8e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 AET38301.1 - 5e-28 97.1 0.1 1.3e-27 95.7 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 AET38301.1 - 3.9e-18 65.4 2.9 1.7e-17 63.4 1.2 2.6 3 1 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 AET38301.1 - 1.8e-12 47.3 0.1 1.5e-10 41.0 0.0 2.9 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 AET38301.1 - 4.2e-07 29.4 0.0 8.1e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AET38301.1 - 2.3e-06 26.6 0.0 5.8e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AET38301.1 - 2.5e-05 24.1 0.1 0.00011 22.0 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AET38301.1 - 0.00084 18.6 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 AET38301.1 - 0.0068 15.8 0.1 0.023 14.1 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GIDA PF01134.17 AET38302.1 - 3.8e-158 526.4 0.0 4.7e-158 526.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 AET38302.1 - 2e-19 69.4 0.0 8.2e-19 67.4 0.0 2.1 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 AET38302.1 - 1.5e-07 31.5 0.3 3.6e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AET38302.1 - 4.5e-06 26.0 0.3 7.2e-06 25.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AET38302.1 - 0.0003 19.7 1.1 0.00079 18.3 0.8 1.7 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AET38302.1 - 0.00052 19.0 1.3 0.35 9.7 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 AET38302.1 - 0.037 14.4 0.7 0.1 13.0 0.5 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AET38302.1 - 1.9 6.8 6.4 5 5.4 1.3 2.5 3 0 0 3 3 3 0 HI0933-like protein CBFB_NFYA PF02045.10 AET38304.1 - 4.5e-27 94.3 9.6 4.5e-27 94.3 6.7 2.0 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF2058 PF09831.4 AET38304.1 - 1.2 8.9 8.8 0.28 11.0 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Cse1 PF08506.5 AET38305.1 - 9.2e-171 567.3 6.5 9.2e-171 567.3 4.5 2.1 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 AET38305.1 - 1.4e-107 359.6 8.0 1.4e-107 359.6 5.5 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 AET38305.1 - 5.6e-16 58.2 3.2 4.7e-15 55.2 0.0 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 AET38305.1 - 0.0044 17.2 0.0 0.58 10.4 0.0 3.5 3 1 0 3 3 3 1 HEAT repeats APC10 PF03256.11 AET38306.1 - 1.7e-55 187.6 0.0 2e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 AET38306.1 - 0.00032 20.5 0.1 0.00069 19.4 0.0 1.7 2 1 0 2 2 2 1 F5/8 type C domain QRPTase_C PF01729.14 AET38307.1 - 2e-56 190.1 0.0 2.5e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 AET38307.1 - 1.1e-21 76.4 0.0 3.6e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain IBN_N PF03810.14 AET38308.1 - 8.8e-08 31.9 0.0 5.6e-07 29.3 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ank PF00023.25 AET38309.1 - 6.1e-13 47.8 0.1 0.00046 19.8 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 AET38309.1 - 1.2e-10 41.5 0.0 1.4e-07 31.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AET38309.1 - 8.4e-10 38.9 0.2 2.6e-06 27.8 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AET38309.1 - 1.6e-09 37.6 0.0 1.2e-05 25.4 0.0 3.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET38309.1 - 3.6e-09 35.9 0.0 0.0011 19.0 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat DUF1717 PF05414.6 AET38309.1 - 0.04 14.3 0.3 0.076 13.4 0.2 1.5 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) A_deamin PF02137.13 AET38310.1 - 2.9e-61 207.6 0.0 3.5e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain APOBEC_N PF08210.6 AET38310.1 - 0.00018 21.1 0.1 0.00033 20.3 0.1 1.4 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Plus-3 PF03126.13 AET38311.1 - 1.3e-33 115.2 0.1 1.3e-33 115.2 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain DUF155 PF02582.9 AET38312.1 - 2.1e-60 203.6 0.2 4e-60 202.6 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Spt20 PF12090.3 AET38312.1 - 0.0049 16.2 1.5 0.0075 15.6 1.1 1.3 1 0 0 1 1 1 1 Spt20 family Med3 PF11593.3 AET38312.1 - 0.066 12.4 5.0 0.12 11.6 3.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BAF1_ABF1 PF04684.8 AET38312.1 - 0.44 9.3 10.1 0.66 8.7 7.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RAI1 PF08652.6 AET38313.1 - 1.3e-26 92.1 0.2 2.5e-26 91.2 0.2 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Brr6_like_C_C PF10104.4 AET38314.1 - 1.8e-41 140.8 1.6 2.1e-41 140.6 1.1 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2975 PF11188.3 AET38314.1 - 0.12 12.1 1.2 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) zf-CHY PF05495.7 AET38314.1 - 1.2 9.3 5.9 6.9 6.9 0.4 2.3 1 1 1 2 2 2 0 CHY zinc finger PAPS_reduct PF01507.14 AET38315.1 - 5.6e-42 143.5 0.0 6.9e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Med10 PF09748.4 AET38316.1 - 1.3e-46 157.5 0.4 1.7e-46 157.1 0.3 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF342 PF03961.8 AET38316.1 - 0.035 12.5 0.2 0.04 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PBS_linker_poly PF00427.16 AET38316.1 - 0.036 13.7 0.3 0.1 12.2 0.2 1.7 1 1 0 1 1 1 0 Phycobilisome Linker polypeptide DUF4455 PF14643.1 AET38316.1 - 0.05 12.2 0.3 0.54 8.8 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) NPV_P10 PF05531.7 AET38316.1 - 0.069 13.4 1.2 0.47 10.7 0.4 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Serine_rich PF08824.5 AET38316.1 - 0.075 12.7 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Serine rich protein interaction domain DUF615 PF04751.9 AET38316.1 - 0.097 12.3 0.4 1.4 8.5 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF615) DUF1978 PF09321.5 AET38316.1 - 0.12 11.7 0.5 0.16 11.3 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) WD40 PF00400.27 AET38317.1 - 5.9e-05 22.7 0.0 0.67 9.9 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.1 AET38317.1 - 0.027 14.7 0.2 9.9 6.5 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain DUF4149 PF13664.1 AET38318.1 - 5.5e-17 61.6 2.1 5.5e-17 61.6 1.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MAS20 PF02064.10 AET38319.1 - 1.2e-15 57.5 0.2 1e-14 54.4 0.1 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor SLX9 PF15341.1 AET38320.1 - 1e-22 80.8 5.2 1e-22 80.8 3.6 1.6 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF3818 PF12825.2 AET38321.1 - 8.1e-120 399.5 7.2 1.7e-119 398.5 5.0 1.6 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 AET38321.1 - 4.3e-45 152.7 0.9 9.4e-45 151.5 0.6 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 AET38321.1 - 2.6e-11 43.3 0.2 3e-10 39.8 0.0 3.0 2 1 0 2 2 2 1 PX domain Sld5 PF05916.6 AET38321.1 - 0.0071 16.6 1.1 2.4 8.4 0.1 3.7 3 0 0 3 3 3 1 GINS complex protein Gpi1 PF05024.10 AET38321.1 - 0.02 14.5 0.1 0.047 13.3 0.1 1.5 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) HypD PF01924.11 AET38321.1 - 0.087 11.5 0.2 0.16 10.6 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase formation hypA family L51_S25_CI-B8 PF05047.11 AET38322.1 - 1.6e-13 50.1 0.1 2.8e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SAM_MT PF04445.8 AET38322.1 - 0.041 13.0 0.0 0.056 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase IF-2B PF01008.12 AET38323.1 - 7.6e-97 323.6 0.0 1.3e-96 322.9 0.0 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4463 PF14703.1 AET38323.1 - 6.9 7.2 12.3 15 6.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) BCAS2 PF05700.6 AET38325.1 - 2.3e-10 40.3 15.1 1.5e-09 37.6 10.5 2.1 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) EF_TS PF00889.14 AET38325.1 - 0.1 11.9 1.0 0.19 11.0 0.7 1.7 1 1 0 1 1 1 0 Elongation factor TS AAR2 PF05282.6 AET38325.1 - 0.1 11.5 6.1 0.14 11.0 4.2 1.1 1 0 0 1 1 1 0 AAR2 protein Ribosomal_L5_C PF00673.16 AET38326.1 - 3.4e-23 81.1 0.0 4.9e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AET38326.1 - 6.6e-20 70.6 0.1 1.9e-19 69.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Proteasome PF00227.21 AET38327.1 - 9.3e-49 165.2 0.2 1.1e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Fork_head PF00250.13 AET38328.1 - 1.1e-32 111.9 0.5 2.8e-32 110.6 0.3 1.7 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 AET38328.1 - 2.2e-11 43.7 0.1 5.2e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 FHA domain COG4 PF08318.7 AET38329.1 - 1.9e-103 345.7 6.5 4.5e-103 344.4 4.5 1.7 1 0 0 1 1 1 1 COG4 transport protein Baculo_PEP_C PF04513.7 AET38329.1 - 0.67 9.7 14.7 1.5 8.6 2.9 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pil1 PF13805.1 AET38330.1 - 1.5e-153 509.6 0.3 1.7e-153 509.4 0.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 AET38330.1 - 0.065 12.5 1.5 0.11 11.8 1.0 1.3 1 0 0 1 1 1 0 FAM92 protein Pkinase PF00069.20 AET38331.1 - 4.8e-15 55.4 0.0 9.5e-15 54.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38331.1 - 1.9e-07 30.4 0.0 2.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AET38331.1 - 0.0031 17.2 0.3 0.0053 16.5 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-CCCH PF00642.19 AET38332.1 - 2.5e-12 46.1 28.2 0.00063 19.3 0.6 5.5 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CBM_19 PF03427.8 AET38332.1 - 0.21 11.4 3.1 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) FUN14 PF04930.10 AET38333.1 - 1.4e-06 28.4 2.6 5.6e-06 26.5 1.8 2.1 1 1 0 1 1 1 1 FUN14 family B56 PF01603.15 AET38334.1 - 2.7e-145 484.0 15.2 2.4e-138 461.1 7.5 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Spo7 PF03907.8 AET38335.1 - 2.5e-90 301.6 9.0 3e-90 301.3 6.2 1.1 1 0 0 1 1 1 1 Spo7-like protein OPT PF03169.10 AET38335.1 - 0.0064 14.9 0.0 0.01 14.3 0.0 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3671 PF12420.3 AET38335.1 - 0.013 15.4 0.2 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF3722 PF12519.3 AET38336.1 - 2.8e-78 262.7 12.7 3.7e-78 262.3 7.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3722) DUF228 PF02989.9 AET38336.1 - 0.072 12.6 0.3 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Lyme disease proteins of unknown function SMC_N PF02463.14 AET38338.1 - 1.2e-20 73.6 16.0 6.1e-20 71.4 11.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AET38338.1 - 1.7e-16 61.2 17.9 1.7e-16 61.2 12.4 5.9 3 2 1 4 4 1 1 AAA domain AAA_29 PF13555.1 AET38338.1 - 1.6e-05 24.2 0.0 3.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 AET38338.1 - 0.00014 21.9 0.2 0.00014 21.9 0.2 4.9 3 2 1 4 4 3 1 AAA domain Spc7 PF08317.6 AET38338.1 - 0.00074 18.2 14.0 0.00074 18.2 9.7 5.6 2 2 2 5 5 4 1 Spc7 kinetochore protein AAA_25 PF13481.1 AET38338.1 - 0.0087 15.4 0.0 0.05 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain NPV_P10 PF05531.7 AET38338.1 - 0.05 13.8 0.5 0.05 13.8 0.3 5.8 5 3 1 6 6 5 0 Nucleopolyhedrovirus P10 protein AAA_16 PF13191.1 AET38338.1 - 0.073 13.0 0.2 6.1 6.7 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 AET38338.1 - 0.2 11.9 0.1 0.2 11.9 0.1 5.3 3 2 1 4 4 2 0 ABC transporter AAA_10 PF12846.2 AET38338.1 - 0.57 9.5 8.3 0.29 10.5 0.1 2.8 3 0 0 3 3 3 0 AAA-like domain Reo_sigmaC PF04582.7 AET38338.1 - 0.63 9.1 12.6 0.63 9.1 0.4 3.7 2 2 3 5 5 5 0 Reovirus sigma C capsid protein tRNA-synt_1c PF00749.16 AET38339.1 - 4.4e-106 354.0 0.0 5.8e-106 353.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF775 PF05603.7 AET38340.1 - 2.4e-55 187.2 0.2 2.8e-55 187.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Ribosomal_S20p PF01649.13 AET38341.1 - 0.091 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S20 Cys_Met_Meta_PP PF01053.15 AET38342.1 - 2.3e-141 470.5 0.1 2.6e-141 470.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AET38342.1 - 7.8e-07 28.3 0.1 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 AET38342.1 - 2.8e-05 22.6 0.0 4.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 AET38342.1 - 0.047 12.4 0.1 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V GDC-P PF02347.11 AET38342.1 - 0.052 12.2 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Ribosomal_S19 PF00203.16 AET38343.1 - 1.3e-32 111.2 0.4 2.1e-32 110.5 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S19 FliH PF02108.11 AET38343.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Sds3 PF08598.6 AET38344.1 - 6.4e-50 169.5 1.4 6.4e-50 169.5 1.0 2.8 2 1 0 2 2 2 1 Sds3-like RRM_1 PF00076.17 AET38345.1 - 7.4e-15 54.3 0.1 2.5e-12 46.2 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET38345.1 - 2.8e-13 49.6 0.1 4.3e-11 42.6 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET38345.1 - 2.1e-09 37.1 0.2 5.4e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AET38345.1 - 0.028 14.2 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif YqzL PF14006.1 AET38345.1 - 7.9 6.7 8.0 22 5.3 0.0 4.0 4 0 0 4 4 4 0 YqzL-like protein SNARE PF05739.14 AET38346.1 - 2.9e-08 33.2 5.4 5e-08 32.5 3.7 1.4 1 0 0 1 1 1 1 SNARE domain FUSC-like PF12805.2 AET38346.1 - 0.29 10.0 2.2 0.44 9.4 1.5 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Neur_chan_memb PF02932.11 AET38347.1 - 1.4 8.6 4.9 1.9 8.3 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exo_endo_phos PF03372.18 AET38348.1 - 1.2e-16 61.4 0.0 1.5e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HhH-GPD PF00730.20 AET38349.1 - 1.2e-18 67.3 0.0 1.8e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AET38349.1 - 0.00013 21.4 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HEAT PF02985.17 AET38350.1 - 2.7e-46 151.4 22.3 0.00055 19.7 0.0 12.8 12 0 0 12 12 12 12 HEAT repeat HEAT_2 PF13646.1 AET38350.1 - 3.5e-35 120.1 0.1 6e-07 29.6 0.0 8.1 1 1 6 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.2 AET38350.1 - 2e-15 56.9 4.4 0.026 14.8 0.0 8.7 3 3 6 9 9 9 5 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 AET38350.1 - 4.1e-15 55.7 8.2 0.36 11.3 0.0 9.0 9 2 1 10 10 10 5 HEAT-like repeat Adaptin_N PF01602.15 AET38350.1 - 1.3e-08 33.6 8.4 0.043 12.1 0.7 4.0 1 1 1 3 3 3 3 Adaptin N terminal region Arm PF00514.18 AET38350.1 - 0.068 13.0 5.9 6.1 6.8 0.0 6.4 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 AET38352.1 - 2e-59 200.8 0.0 2e-59 200.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38352.1 - 2.2e-22 79.4 0.3 4.4e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38352.1 - 9.5e-07 28.0 0.0 1.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AET38352.1 - 0.0044 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET38352.1 - 0.0086 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3595 PF12166.3 AET38354.1 - 0.062 12.1 0.1 0.062 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) DUF3439 PF11921.3 AET38354.1 - 0.8 9.4 4.7 4.7 6.9 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) EI24 PF07264.6 AET38354.1 - 0.97 8.8 21.1 14 5.0 14.6 2.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) GSH_synth_ATP PF03917.12 AET38355.1 - 1.8e-111 372.3 0.0 2.2e-111 372.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 AET38355.1 - 3.6e-36 123.4 0.2 5.9e-36 122.7 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Capsid_NCLDV PF04451.7 AET38355.1 - 0.038 12.9 0.1 0.42 9.5 0.0 2.0 2 0 0 2 2 2 0 Large eukaryotic DNA virus major capsid protein Med15_fungi PF05397.7 AET38356.1 - 6.1e-41 139.0 6.5 6.1e-41 139.0 4.5 7.6 5 3 0 6 6 6 1 Mediator complex subunit 15 SNF2_N PF00176.18 AET38357.1 - 6.3e-70 235.3 0.7 6.3e-70 235.3 0.5 2.4 2 1 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AET38357.1 - 9.8e-17 60.5 0.0 2.7e-15 55.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CUE PF02845.11 AET38357.1 - 0.0039 16.6 0.0 0.014 14.8 0.0 2.1 1 0 0 1 1 1 1 CUE domain Tom37_C PF11801.3 AET38357.1 - 2.2 8.1 7.4 1.4 8.7 0.1 2.9 2 0 0 2 2 2 0 Tom37 C-terminal domain ECH PF00378.15 AET38358.1 - 2.7e-24 85.6 0.1 7.1e-24 84.2 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AET38358.1 - 7.5e-17 61.5 1.5 2.3e-16 60.0 0.5 2.0 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Topoisom_I_N PF02919.10 AET38358.1 - 0.0072 15.6 1.9 0.016 14.5 1.3 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Lipid_DES PF08557.5 AET38359.1 - 2.9e-19 68.0 0.9 4.9e-19 67.2 0.6 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.19 AET38359.1 - 6.3e-17 61.8 18.4 4.5e-16 59.0 12.8 2.2 1 1 0 1 1 1 1 Fatty acid desaturase RinB PF06116.7 AET38360.1 - 0.11 12.0 1.1 0.21 11.2 0.7 1.4 1 0 0 1 1 1 0 Transcriptional activator RinB Pkinase PF00069.20 AET38361.1 - 2.7e-38 131.5 0.2 2.7e-38 131.5 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38361.1 - 1.2e-28 99.8 0.0 2.3e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38361.1 - 0.00064 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AET38361.1 - 0.025 14.3 0.0 0.22 11.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family ORC2 PF04084.9 AET38362.1 - 2.8e-99 332.0 8.6 3.7e-99 331.6 5.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 TFIIS_C PF01096.13 AET38363.1 - 5.5e-22 77.1 2.3 5.5e-22 77.1 1.6 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AET38363.1 - 6.8e-11 41.6 4.4 1.2e-10 40.9 0.8 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Terminase_GpA PF05876.7 AET38363.1 - 0.0017 16.8 0.7 0.067 11.5 0.5 2.0 1 1 0 1 1 1 1 Phage terminase large subunit (GpA) DZR PF12773.2 AET38363.1 - 0.021 14.6 5.9 0.21 11.4 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.1 AET38363.1 - 0.03 14.6 4.7 1.7 8.9 3.2 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar Desulfoferrod_N PF06397.7 AET38363.1 - 0.066 12.6 0.2 0.19 11.1 0.1 1.8 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain IBR PF01485.16 AET38363.1 - 0.12 12.2 0.3 0.12 12.2 0.2 3.0 2 1 0 2 2 2 0 IBR domain C1_1 PF00130.17 AET38363.1 - 0.14 11.9 2.3 0.68 9.7 0.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.2 AET38363.1 - 0.16 11.8 7.2 0.5 10.2 0.2 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.3 AET38363.1 - 0.2 11.0 3.1 0.28 10.6 0.2 2.4 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Elf1 PF05129.8 AET38363.1 - 0.35 10.5 2.2 6.5 6.5 0.0 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like PhnA_Zn_Ribbon PF08274.7 AET38363.1 - 0.83 9.4 7.8 5.1 6.9 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-AN1 PF01428.11 AET38363.1 - 1.5 8.7 4.5 6 6.8 0.1 3.0 3 1 0 3 3 3 0 AN1-like Zinc finger zinc_ribbon_5 PF13719.1 AET38363.1 - 4.7 6.8 10.8 6.7 6.3 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AET38363.1 - 5.5 6.3 10.0 11 5.4 1.0 3.1 2 2 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 AET38363.1 - 7.3 6.3 11.1 7.1 6.4 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Coprogen_oxidas PF01218.13 AET38364.1 - 1e-132 441.2 0.0 1.1e-132 441.0 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase zf-H2C2_2 PF13465.1 AET38365.1 - 4e-06 26.8 13.9 0.00014 21.9 2.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 AET38365.1 - 4e-05 23.6 20.2 0.00052 20.2 2.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET38365.1 - 0.0017 18.5 16.3 0.24 11.8 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AET38365.1 - 0.063 13.4 0.3 0.063 13.4 0.2 2.8 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf-RING-like PF08746.6 AET38365.1 - 3.9 7.5 8.2 0.34 10.9 1.4 2.0 2 0 0 2 2 2 0 RING-like domain zf-RING_2 PF13639.1 AET38369.1 - 1.4e-09 37.6 10.8 2.1e-09 37.0 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AET38369.1 - 5.1e-09 36.1 8.2 1.1e-08 35.0 5.7 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AET38369.1 - 7.6e-06 25.6 5.8 1.9e-05 24.3 4.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 AET38369.1 - 0.00012 21.6 11.8 0.00018 21.0 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AET38369.1 - 0.0071 15.9 8.3 0.011 15.3 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET38369.1 - 0.021 14.8 12.4 0.039 13.9 8.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET38369.1 - 0.1 12.3 9.8 0.15 11.7 6.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.9 AET38369.1 - 0.23 10.9 11.1 1.3 8.5 6.6 2.2 1 1 1 2 2 2 0 P-11 zinc finger zf-Nse PF11789.3 AET38369.1 - 0.33 10.5 5.9 0.6 9.6 4.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 AET38369.1 - 2.9 7.9 14.5 1.1 9.2 6.3 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 AET38369.1 - 6 6.8 10.8 13 5.7 7.5 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Ribosomal_S10 PF00338.17 AET38370.1 - 1.3e-28 98.6 0.0 7.7e-28 96.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e FtsJ PF01728.14 AET38371.1 - 4.2e-63 212.6 0.1 5.1e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 AET38371.1 - 0.057 14.0 0.0 0.29 11.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain AA_permease PF00324.16 AET38372.1 - 2.4e-121 405.3 37.1 2.9e-121 405.1 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET38372.1 - 4.6e-33 114.3 36.4 5.7e-33 114.0 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AET38373.1 - 6.6e-115 384.1 38.2 8.6e-115 383.8 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET38373.1 - 8.4e-26 90.4 37.4 1e-25 90.1 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3899 PF13038.1 AET38373.1 - 0.36 11.0 0.0 0.36 11.0 0.0 4.6 5 1 1 6 6 6 0 Domain of unknown function (DUF3899) AA_permease PF00324.16 AET38374.1 - 2.9e-131 438.0 38.5 3.7e-131 437.7 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET38374.1 - 7.1e-37 126.9 38.9 8.7e-37 126.6 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease TIM PF00121.13 AET38376.1 - 2.3e-88 295.3 0.0 2.6e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Alg14 PF08660.6 AET38377.1 - 2.3e-50 170.8 0.1 2.9e-50 170.6 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PsiB PF06290.6 AET38377.1 - 0.046 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) UQ_con PF00179.21 AET38379.1 - 1.9e-44 150.4 0.0 2.5e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AET38379.1 - 0.0035 17.0 0.0 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B AMNp_N PF10423.4 AET38379.1 - 0.093 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus NOA36 PF06524.7 AET38379.1 - 3.1 6.9 14.3 4.1 6.5 9.9 1.1 1 0 0 1 1 1 0 NOA36 protein Fimbrial_PilY2 PF14481.1 AET38380.1 - 0.018 14.4 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Dfp1_Him1_M PF08630.5 AET38381.1 - 9.5e-45 151.4 0.0 3.3e-44 149.6 0.0 2.0 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 AET38381.1 - 1.1e-20 73.0 1.1 2.3e-20 71.9 0.8 1.5 1 0 0 1 1 1 1 DBF zinc finger Pheromone PF08015.6 AET38381.1 - 0.01 16.6 0.2 0.033 15.0 0.2 1.9 1 0 0 1 1 1 0 Fungal mating-type pheromone Fungal_trans_2 PF11951.3 AET38382.1 - 7.7e-11 41.2 1.4 2.1e-10 39.7 0.0 2.1 1 1 2 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET38382.1 - 2e-05 24.3 9.6 2e-05 24.3 6.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 AET38383.1 - 2.1e-11 43.4 8.4 1.5e-05 25.0 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET38383.1 - 1.9e-06 27.8 0.5 1.9e-06 27.8 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET38383.1 - 2.3e-06 27.5 6.2 0.0032 17.6 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AET38383.1 - 0.011 15.6 6.9 0.23 11.4 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AET38383.1 - 0.037 14.1 1.9 0.26 11.5 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AET38383.1 - 0.15 12.2 2.3 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 AET38383.1 - 0.4 10.6 2.7 5.6 6.9 0.4 2.5 1 1 1 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.9 AET38383.1 - 1.1 9.0 4.2 7.4 6.3 0.2 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid Glyco_hydro_81 PF03639.8 AET38384.1 - 3e-221 736.1 11.3 3.5e-221 735.9 7.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Peptidase_M28 PF04389.12 AET38385.1 - 1.9e-30 105.9 0.0 3.8e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 AET38385.1 - 2.2e-05 24.0 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 AET38385.1 - 0.00022 20.1 0.0 0.00051 18.9 0.0 1.5 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase URO-D PF01208.12 AET38386.1 - 3.7e-119 397.6 0.0 4.2e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ank_5 PF13857.1 AET38387.1 - 0.0021 18.2 0.0 0.0045 17.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Imm42 PF15601.1 AET38387.1 - 0.088 12.2 0.6 0.58 9.5 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 42 SNF2_N PF00176.18 AET38388.1 - 4.1e-57 193.2 0.0 6.4e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AET38388.1 - 7.2e-11 41.8 0.0 1.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AET38388.1 - 1.5e-09 37.1 0.5 4.4e-06 25.7 0.2 2.3 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 AET38388.1 - 4.9e-09 35.9 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 AET38388.1 - 2.3e-07 30.8 0.1 1e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 AET38388.1 - 0.043 12.7 0.0 2.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MFS_1 PF07690.11 AET38389.1 - 3.7e-30 104.8 23.5 3.7e-30 104.8 16.3 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Oxidored_FMN PF00724.15 AET38389.1 - 0.066 12.1 0.0 0.098 11.6 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family P63C PF10546.4 AET38390.1 - 0.066 13.1 0.2 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 P63C domain COX7a PF02238.10 AET38393.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Ion_trans_N PF08412.5 AET38393.1 - 0.12 11.6 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Ion transport protein N-terminal zf-C3HC4_4 PF15227.1 AET38394.1 - 2.2e-07 30.6 3.9 2.2e-07 30.6 2.7 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 AET38394.1 - 2.4e-07 30.4 3.4 2.4e-07 30.4 2.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 AET38394.1 - 6.1e-07 29.0 4.4 6.1e-07 29.0 3.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET38394.1 - 4.3e-06 26.6 3.2 4.3e-06 26.6 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET38394.1 - 4.9e-06 26.1 2.4 4.9e-06 26.1 1.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 AET38394.1 - 2e-05 24.5 7.4 2.8e-05 24.1 1.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 AET38394.1 - 3.8e-05 23.3 0.1 8.2e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 AET38394.1 - 7.4e-05 22.5 3.1 0.00026 20.7 0.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 AET38394.1 - 8.9e-05 22.0 1.8 8.9e-05 22.0 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 AET38394.1 - 0.013 15.2 8.1 0.71 9.7 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 AET38394.1 - 0.029 13.9 11.8 0.039 13.5 2.8 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 AET38394.1 - 0.1 12.4 7.2 3 7.7 0.8 2.6 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zinc_ribbon_4 PF13717.1 AET38394.1 - 0.33 10.6 5.4 33 4.2 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AET38394.1 - 0.37 10.3 5.3 39 3.9 0.2 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 AET38394.1 - 0.45 10.3 5.2 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons ParBc_2 PF08857.6 AET38395.1 - 0.0074 16.1 0.0 6.4 6.5 0.0 2.6 2 0 0 2 2 2 2 Putative ParB-like nuclease WHEP-TRS PF00458.15 AET38395.1 - 0.033 13.8 1.3 0.18 11.5 0.6 2.3 2 0 0 2 2 2 0 WHEP-TRS domain F-box-like PF12937.2 AET38396.1 - 0.015 15.0 0.1 0.047 13.4 0.1 1.9 1 0 0 1 1 1 0 F-box-like DUF2428 PF10350.4 AET38397.1 - 1.9e-71 240.1 0.1 3.6e-71 239.1 0.1 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 AET38397.1 - 5e-05 23.0 4.2 0.0094 15.9 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 AET38397.1 - 0.13 12.5 0.6 10 6.4 0.0 3.6 3 1 1 4 4 4 0 HEAT repeats Mg_trans_NIPA PF05653.9 AET38398.1 - 7.1e-111 369.9 15.5 8.4e-111 369.7 10.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 AET38398.1 - 1.7e-06 28.1 17.5 2e-06 27.9 2.0 3.6 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 AET38398.1 - 6.2e-05 23.0 9.2 6.2e-05 23.0 6.4 3.4 3 1 1 4 4 4 2 EamA-like transporter family DUF2937 PF11157.3 AET38398.1 - 0.14 11.4 2.6 0.2 10.9 0.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) CCSMST1 PF15013.1 AET38398.1 - 0.83 9.6 2.9 19 5.2 0.1 2.8 2 1 1 3 3 3 0 CCSMST1 family eIF-1a PF01176.14 AET38399.1 - 2.1e-26 91.1 0.2 3e-26 90.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 AET38399.1 - 0.0032 17.5 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Glyco_transf_20 PF00982.16 AET38400.1 - 4.5e-159 529.9 0.4 2.4e-158 527.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 AET38400.1 - 7.6e-35 119.9 0.0 1.5e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase TatD_DNase PF01026.16 AET38401.1 - 1.6e-35 122.5 0.0 2.6e-35 121.8 0.0 1.3 1 1 0 1 1 1 1 TatD related DNase SAP30_Sin3_bdg PF13867.1 AET38402.1 - 1e-14 54.0 0.2 3.6e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 NAGLU_N PF12971.2 AET38402.1 - 0.0074 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain CUE PF02845.11 AET38403.1 - 4.8e-11 41.9 0.0 1.1e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 CUE domain Pox_A12 PF04651.8 AET38403.1 - 1.5 8.8 5.4 4.7 7.2 3.7 1.8 1 1 0 1 1 1 0 Poxvirus A12 protein WD40 PF00400.27 AET38404.1 - 8.8e-31 104.6 4.4 4.7e-08 32.6 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 AET38404.1 - 0.00013 21.7 0.1 0.0042 16.8 0.0 2.8 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 AET38404.1 - 0.11 12.2 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF221 PF02714.10 AET38405.1 - 2.3e-101 338.9 26.4 2.3e-101 338.9 18.3 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AET38405.1 - 2.8e-38 130.9 3.5 2.8e-38 130.9 2.4 2.8 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AET38405.1 - 6.5e-27 93.2 0.0 3.6e-26 90.8 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 AET38405.1 - 6.6e-17 61.8 0.2 1.2e-16 60.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Pyrophosphatase PF00719.14 AET38406.1 - 5.8e-50 168.7 0.0 7.7e-50 168.3 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase RRM_1 PF00076.17 AET38407.1 - 3.8e-36 122.5 3.3 5.6e-13 48.3 0.1 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET38407.1 - 4.1e-30 103.5 0.6 4.8e-09 36.0 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET38407.1 - 9.6e-14 50.9 1.4 3.6e-06 26.7 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 AET38407.1 - 0.00021 20.5 0.6 0.00021 20.5 0.4 2.0 2 0 0 2 2 2 1 Lsm interaction motif Nup35_RRM_2 PF14605.1 AET38407.1 - 0.00037 20.2 0.0 0.32 10.7 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif G-patch PF01585.18 AET38408.1 - 0.0015 18.2 1.5 0.0042 16.8 1.0 1.8 1 1 0 1 1 1 1 G-patch domain RNA_polI_A34 PF08208.6 AET38408.1 - 0.14 11.7 23.6 0.22 11.1 16.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_U57 PF05582.7 AET38408.1 - 7.9 5.3 10.9 9.9 5.0 7.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 PXA PF02194.10 AET38409.1 - 5.9e-38 130.3 1.1 5.9e-38 130.3 0.8 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 AET38409.1 - 1.1e-27 96.3 0.1 1.1e-27 96.3 0.1 2.6 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 AET38409.1 - 2.4e-12 46.6 4.6 9.6e-12 44.6 1.3 2.8 2 0 0 2 2 2 1 PX domain RGS PF00615.14 AET38409.1 - 1.7e-07 31.3 2.5 2.7e-07 30.6 0.5 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain RRN9 PF10680.4 AET38410.1 - 2.1e-18 65.8 0.5 5.4e-18 64.4 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor DUF2457 PF10446.4 AET38410.1 - 0.02 13.6 22.2 0.039 12.7 15.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 AET38410.1 - 0.14 11.6 14.0 0.33 10.4 9.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin Cwf_Cwc_15 PF04889.7 AET38410.1 - 0.32 10.6 17.6 0.8 9.3 12.2 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 AET38410.1 - 0.55 9.4 12.1 0.79 8.9 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein BTV_NS2 PF04514.7 AET38410.1 - 0.88 8.3 13.0 1.4 7.6 9.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CENP-B_dimeris PF09026.5 AET38410.1 - 2 8.7 15.6 6.1 7.1 10.8 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tom22 PF04281.8 AET38410.1 - 8.4 5.9 11.3 18 4.8 7.8 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 FLO_LFY PF01698.11 AET38410.1 - 8.9 5.0 12.0 1.9 7.2 6.0 1.5 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF3295 PF11702.3 AET38410.1 - 9.6 5.0 13.2 16 4.3 9.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3295) SRP19 PF01922.12 AET38411.1 - 3e-30 104.6 0.0 6.3e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein Pribosyltran PF00156.22 AET38412.1 - 1.8e-18 66.4 0.4 5.4e-18 64.9 0.2 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain zf-C3HC PF07967.8 AET38413.1 - 1.8e-11 43.9 3.1 8.4e-10 38.5 0.6 2.9 2 1 1 3 3 3 2 C3HC zinc finger-like DUF2847 PF11009.3 AET38413.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) SUN PF03856.8 AET38414.1 - 9.8e-84 280.5 16.2 1.1e-83 280.3 11.2 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Integrin_b_cyt PF08725.6 AET38414.1 - 0.96 8.8 3.5 1 8.7 0.2 2.3 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Abi PF02517.11 AET38415.1 - 2.1e-12 46.9 7.5 2.1e-12 46.9 5.2 2.8 3 0 0 3 3 3 1 CAAX protease self-immunity DUF4029 PF13221.1 AET38415.1 - 0.2 12.0 4.1 0.066 13.6 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) Zds_C PF08632.5 AET38416.1 - 2e-33 113.5 2.0 3.5e-33 112.7 1.4 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF1892 PF08987.5 AET38417.1 - 4.6e-40 136.2 2.6 5.7e-40 135.9 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) PEPcase_2 PF14010.1 AET38417.1 - 0.13 10.5 0.1 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Cyt-b5 PF00173.23 AET38418.1 - 2e-16 59.5 0.1 9.2e-15 54.2 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 AET38418.1 - 8.1e-11 42.3 16.9 1.1e-10 41.9 9.1 2.2 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 AET38418.1 - 0.0079 16.2 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Kua-UEV1_localn PF10520.4 AET38418.1 - 8 6.0 7.8 4.3 6.9 0.6 2.7 2 1 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain ABC_tran PF00005.22 AET38419.1 - 6.9e-45 152.7 4.9 8.5e-23 81.1 0.0 3.4 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 AET38419.1 - 3.7e-19 68.3 9.7 3.7e-19 68.3 6.7 3.3 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 AET38419.1 - 4.6e-17 62.9 16.0 3.3e-06 27.2 0.5 5.2 3 2 1 5 5 5 3 AAA domain SMC_N PF02463.14 AET38419.1 - 5.9e-11 42.0 0.0 0.00018 20.7 0.0 3.5 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 AET38419.1 - 8.2e-09 36.3 3.6 0.00015 22.5 0.0 3.6 4 1 1 5 5 2 2 AAA domain Miro PF08477.8 AET38419.1 - 8.3e-07 29.5 0.3 0.037 14.5 0.2 3.2 2 1 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 AET38419.1 - 1e-06 28.8 0.1 0.043 13.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AET38419.1 - 2.2e-06 26.9 0.1 0.018 14.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 AET38419.1 - 3e-06 27.0 0.3 0.02 14.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 AET38419.1 - 3e-06 27.3 0.7 0.17 11.9 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 AET38419.1 - 8.3e-06 26.2 34.1 0.15 12.3 0.0 5.3 5 0 0 5 5 5 3 AAA domain ATP-synt_ab PF00006.20 AET38419.1 - 1.1e-05 24.9 0.0 0.0048 16.4 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 AET38419.1 - 1.2e-05 25.4 1.0 0.14 12.3 0.0 4.1 5 1 0 5 5 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AET38419.1 - 1.3e-05 25.1 2.8 0.15 11.9 0.1 3.5 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 AET38419.1 - 2.4e-05 24.2 0.1 0.057 13.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain PduV-EutP PF10662.4 AET38419.1 - 5e-05 22.8 0.3 0.17 11.3 0.1 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 AET38419.1 - 5.7e-05 23.4 14.5 0.083 13.1 0.8 4.9 5 2 0 5 5 4 2 AAA domain AAA_29 PF13555.1 AET38419.1 - 8.1e-05 22.0 7.5 0.049 13.1 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 AET38419.1 - 8.8e-05 22.5 4.1 0.12 12.3 0.8 3.3 3 1 0 3 3 2 2 AAA ATPase domain NB-ARC PF00931.17 AET38419.1 - 9.9e-05 21.3 0.1 0.15 10.9 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain MobB PF03205.9 AET38419.1 - 0.0001 21.9 0.1 0.15 11.8 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AET38419.1 - 0.00015 21.6 0.9 0.16 11.9 0.0 4.0 3 1 1 4 4 3 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 AET38419.1 - 0.00023 21.2 0.6 0.5 10.5 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_10 PF12846.2 AET38419.1 - 0.00025 20.5 0.3 0.69 9.2 0.0 2.8 2 1 0 2 2 2 2 AAA-like domain SbcCD_C PF13558.1 AET38419.1 - 0.00071 19.4 0.1 1.5 8.8 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 AET38419.1 - 0.00099 18.8 0.0 0.78 9.4 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_15 PF13175.1 AET38419.1 - 0.0013 17.8 28.0 0.1 11.6 0.0 6.1 2 1 2 4 4 2 1 AAA ATPase domain AAA_25 PF13481.1 AET38419.1 - 0.0019 17.6 0.0 1.8 7.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.7 AET38419.1 - 0.0033 16.7 0.5 0.16 11.2 0.0 2.7 3 0 0 3 3 3 1 Poxvirus A32 protein ArgK PF03308.11 AET38419.1 - 0.0039 16.0 0.1 0.42 9.3 0.0 2.7 2 0 0 2 2 2 1 ArgK protein AAA_5 PF07728.9 AET38419.1 - 0.0045 16.7 0.1 4.8 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 AET38419.1 - 0.01 15.0 0.0 4.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.14 AET38419.1 - 0.011 15.1 0.5 3.5 7.0 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 AET38419.1 - 0.015 14.9 0.0 4.7 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 AET38419.1 - 0.025 13.4 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 AET38419.1 - 0.04 13.3 2.4 12 5.2 0.0 3.5 3 0 0 3 3 3 0 Ras family FtsK_SpoIIIE PF01580.13 AET38419.1 - 0.047 13.1 0.4 2.3 7.6 0.0 3.2 3 1 1 4 4 3 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 AET38419.1 - 0.07 12.6 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.13 AET38419.1 - 0.55 9.1 10.3 1 8.2 0.2 3.4 3 1 0 3 3 3 0 Septin Dynamin_N PF00350.18 AET38419.1 - 0.72 9.6 15.8 0.041 13.7 0.9 3.9 3 1 1 4 4 4 0 Dynamin family RNB PF00773.14 AET38420.1 - 2.6e-95 319.4 0.6 5.9e-95 318.2 0.4 1.6 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 AET38420.1 - 8.5e-15 55.0 0.7 2.1e-14 53.7 0.5 1.7 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 AET38420.1 - 0.097 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain AA_permease PF00324.16 AET38421.1 - 2.7e-112 375.5 39.6 3.2e-112 375.3 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET38421.1 - 1.1e-31 109.8 39.2 1.3e-31 109.6 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease UCH PF00443.24 AET38422.1 - 4.9e-53 179.9 0.1 6.4e-53 179.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AET38422.1 - 9.5e-17 61.3 2.6 2.8e-16 59.8 1.8 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 AET38422.1 - 0.0027 17.0 0.0 0.0093 15.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family RNase_H2-Ydr279 PF09468.5 AET38422.1 - 0.0074 15.5 0.7 3.4 6.7 0.0 2.6 2 1 0 2 2 2 2 Ydr279p protein family (RNase H2 complex component) DUF1690 PF07956.6 AET38423.1 - 4.8e-40 136.7 3.6 5.4e-40 136.6 2.5 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) SPX PF03105.14 AET38423.1 - 0.053 13.2 2.7 0.061 13.0 1.9 1.1 1 0 0 1 1 1 0 SPX domain DUF3518 PF12031.3 AET38423.1 - 0.081 11.7 0.5 0.095 11.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) HEXIM PF15313.1 AET38423.1 - 0.13 12.4 2.7 0.26 11.4 1.8 1.6 1 1 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein Vhr1 PF04001.8 AET38423.1 - 0.24 11.3 3.5 0.68 9.8 1.3 2.0 1 1 1 2 2 2 0 Transcription factor Vhr1 SUR7 PF06687.7 AET38424.1 - 6.6e-18 65.0 12.4 9.2e-18 64.5 8.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family Polysacc_synt_3 PF13440.1 AET38424.1 - 0.018 14.5 6.1 0.037 13.5 4.2 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein OppC_N PF12911.2 AET38424.1 - 0.072 12.4 0.6 0.42 10.0 0.3 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF607 PF04678.8 AET38424.1 - 1.5 8.7 2.6 1.3 8.8 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF4131 PF13567.1 AET38424.1 - 1.7 8.0 8.8 0.027 13.8 0.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) N1221 PF07923.8 AET38425.1 - 0.05 12.4 0.1 0.064 12.1 0.1 1.1 1 0 0 1 1 1 0 N1221-like protein Clat_adaptor_s PF01217.15 AET38426.1 - 1.3e-53 180.5 1.1 1.5e-53 180.3 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 AET38427.1 - 4.5e-26 91.8 0.0 6.7e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 AET38427.1 - 0.00069 19.3 0.0 0.0034 17.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4434) Mpv17_PMP22 PF04117.7 AET38430.1 - 7e-26 89.6 5.0 1.3e-25 88.7 3.5 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family ABC1 PF03109.11 AET38431.1 - 5.5e-32 110.2 0.0 1.3e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 AET38431.1 - 0.00055 19.3 0.0 0.0018 17.6 0.0 1.9 2 0 0 2 2 2 1 RIO1 family DUF904 PF06005.7 AET38432.1 - 0.0021 18.3 16.3 0.27 11.5 1.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF904) Baculo_PEP_C PF04513.7 AET38432.1 - 0.059 13.1 2.6 0.11 12.3 1.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2937 PF11157.3 AET38432.1 - 0.077 12.3 1.9 0.12 11.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Syntaxin PF00804.20 AET38432.1 - 0.1 12.7 7.9 0.2 11.8 5.5 1.5 1 0 0 1 1 1 0 Syntaxin DUF1479 PF07350.7 AET38432.1 - 0.44 8.9 3.0 0.54 8.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) GBP_C PF02841.9 AET38432.1 - 1.3 8.1 9.6 1.8 7.7 6.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain TMF_DNA_bd PF12329.3 AET38432.1 - 2.1 8.2 10.7 1.8 8.3 4.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 AET38432.1 - 2.5 7.0 14.0 3.4 6.6 9.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SPX PF03105.14 AET38432.1 - 2.7 7.6 8.0 5.9 6.5 5.6 1.5 1 1 0 1 1 1 0 SPX domain TBPIP PF07106.8 AET38432.1 - 5.8 6.4 11.3 3 7.3 4.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) YlqD PF11068.3 AET38432.1 - 5.9 6.9 14.6 29 4.7 10.1 1.9 1 1 0 1 1 1 0 YlqD protein OCD_Mu_crystall PF02423.10 AET38433.1 - 1.9e-09 36.7 0.0 2.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Fungal_trans PF04082.13 AET38434.1 - 4.4e-10 38.8 3.2 1.1e-09 37.5 2.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET38434.1 - 1.2e-08 34.7 8.0 2.8e-08 33.5 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferric_reduct PF01794.14 AET38435.1 - 8.5e-17 61.4 11.5 4.5e-16 59.0 8.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 AET38435.1 - 3.5e-11 42.9 0.0 6.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 AET38435.1 - 1.9e-09 37.6 0.0 3.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Peptidase_M28 PF04389.12 AET38436.1 - 4.5e-37 127.5 0.0 6.2e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 ABC2_membrane PF01061.19 AET38437.1 - 1.5e-35 122.2 17.6 1.5e-35 122.2 12.2 1.8 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 AET38437.1 - 4.4e-26 91.8 0.0 8e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 AET38437.1 - 0.00089 18.4 0.5 0.0023 17.1 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AET38437.1 - 0.006 16.5 0.0 0.019 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AET38437.1 - 0.029 14.4 0.0 0.083 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AET38437.1 - 0.035 13.5 0.2 5.7 6.2 0.2 2.5 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 AET38437.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AET38437.1 - 0.096 12.2 0.2 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain hEGF PF12661.2 AET38437.1 - 0.28 11.3 9.7 3.6 7.8 1.7 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF RNA_pol_Rpc34 PF05158.7 AET38438.1 - 2.2e-103 345.8 1.7 2.7e-103 345.5 1.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.14 AET38438.1 - 0.0097 15.5 0.8 0.75 9.5 0.3 2.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 AET38438.1 - 0.02 14.7 2.3 0.06 13.1 0.1 2.5 1 1 2 3 3 3 0 B-block binding subunit of TFIIIC Rrf2 PF02082.15 AET38438.1 - 0.043 13.9 0.7 0.094 12.8 0.1 1.8 2 0 0 2 2 2 0 Transcriptional regulator RPA_C PF08784.6 AET38438.1 - 0.054 13.9 0.3 0.42 11.0 0.1 2.4 1 1 1 2 2 2 0 Replication protein A C terminal HTH_24 PF13412.1 AET38438.1 - 0.09 12.1 2.0 0.56 9.6 0.1 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding OPT PF03169.10 AET38439.1 - 3.8e-148 494.7 40.9 4.3e-148 494.5 28.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Grp1_Fun34_YaaH PF01184.14 AET38441.1 - 1.9e-82 275.6 18.1 2.4e-82 275.3 12.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3953 PF13129.1 AET38441.1 - 0.041 13.5 0.4 0.041 13.5 0.3 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3953) 2TM PF13239.1 AET38441.1 - 2.5 8.2 5.3 3.5 7.7 2.8 2.0 1 1 0 1 1 1 0 2TM domain BAR PF03114.13 AET38442.1 - 2.7e-53 180.8 1.1 3.6e-53 180.4 0.7 1.1 1 0 0 1 1 1 1 BAR domain DUF1496 PF07383.7 AET38442.1 - 0.0033 16.6 0.2 0.0063 15.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1496) DUF4164 PF13747.1 AET38442.1 - 0.16 12.1 0.2 0.16 12.1 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Sterol-sensing PF12349.3 AET38443.1 - 6.1e-05 22.5 13.4 0.00035 20.0 8.4 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Lir1 PF07207.6 AET38443.1 - 0.042 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Light regulated protein Lir1 Pkinase PF00069.20 AET38444.1 - 5.1e-64 215.9 0.0 8.4e-64 215.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38444.1 - 7e-25 87.5 0.0 9.6e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38444.1 - 0.0019 17.2 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AET38444.1 - 0.14 11.8 0.4 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 AET38444.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.17 AET38445.1 - 7.9e-48 159.9 7.3 1.7e-17 62.7 0.4 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET38445.1 - 3.3e-30 103.8 0.8 2.6e-10 40.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET38445.1 - 7.2e-24 83.4 0.5 1.7e-08 34.1 0.5 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AET38445.1 - 7.1e-05 22.5 0.2 1 9.2 0.0 3.7 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 AET38445.1 - 0.0013 18.4 0.0 1.4 8.7 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Myc_N PF01056.13 AET38445.1 - 0.046 12.8 3.2 0.085 12.0 2.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF500 PF04366.7 AET38446.1 - 1.3e-44 150.6 1.8 1.5e-44 150.4 0.3 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 AET38446.1 - 4.5e-16 57.9 0.1 9.1e-16 56.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AET38446.1 - 1.1e-13 50.4 0.1 3.1e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AET38446.1 - 1.2e-11 43.9 0.0 2.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.3 AET38446.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Apc4_WD40 PF12894.2 AET38446.1 - 0.11 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain SAP25 PF15476.1 AET38446.1 - 0.15 11.5 0.7 0.9 9.0 0.0 2.2 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP25 DUF1776 PF08643.5 AET38447.1 - 6.2e-67 225.8 0.1 1.8e-66 224.3 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Lyase_1 PF00206.15 AET38448.1 - 5.1e-95 318.2 0.0 7.5e-95 317.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 AET38448.1 - 2.6e-25 88.2 0.0 5e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal tRNA-synt_2 PF00152.15 AET38449.1 - 2.6e-75 253.2 0.2 4.7e-75 252.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AET38449.1 - 3.1e-11 42.9 0.1 6.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.6 AET38449.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase ThylakoidFormat PF11264.3 AET38449.1 - 0.13 11.8 1.6 0.24 11.0 1.1 1.3 1 0 0 1 1 1 0 Thylakoid formation protein ProRS-C_1 PF09180.6 AET38450.1 - 7.4e-24 83.4 1.0 1.4e-23 82.6 0.7 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 AET38450.1 - 3.6e-22 78.7 0.0 5.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AET38450.1 - 5.1e-18 64.8 0.0 1.8e-17 63.0 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 AET38450.1 - 0.027 14.3 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain PHP PF02811.14 AET38451.1 - 1.4e-19 70.5 0.1 4.1e-19 69.0 0.0 1.8 1 1 0 1 1 1 1 PHP domain Rho_Binding PF08912.6 AET38451.1 - 0.034 14.4 0.0 3.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Rho Binding DUF3605 PF12239.3 AET38451.1 - 0.059 13.2 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) Flo11 PF10182.4 AET38452.1 - 7.7e-42 142.4 0.1 2e-41 141.0 0.1 1.8 1 0 0 1 1 1 1 Flo11 domain Collagen PF01391.13 AET38452.1 - 0.00011 21.6 17.8 0.00023 20.6 3.8 2.8 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) Acetyltransf_13 PF13880.1 AET38453.1 - 3e-21 74.9 0.1 5.6e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 AET38453.1 - 1.3e-08 34.3 0.7 2.2e-08 33.4 0.5 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 AET38453.1 - 0.021 14.8 0.1 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AET38453.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPn PF14671.1 AET38454.1 - 2.8e-50 169.9 0.0 7.1e-50 168.6 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 AET38454.1 - 1.1e-22 79.9 0.0 1.7e-21 76.2 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AET38454.1 - 8.5e-05 22.0 0.3 0.00025 20.4 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 AET38454.1 - 0.0082 15.6 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 AET38454.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 AET38454.1 - 0.13 12.5 0.8 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Glutaredoxin PF00462.19 AET38456.1 - 1.4e-06 28.1 0.0 2.9e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin DUF953 PF06110.6 AET38456.1 - 0.0019 17.6 0.7 0.0032 16.9 0.5 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.1 AET38456.1 - 0.012 15.7 0.1 0.021 15.0 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AET38456.1 - 0.033 13.7 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.15 AET38456.1 - 0.12 12.0 0.4 0.17 11.6 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin MFS_1 PF07690.11 AET38457.1 - 2.7e-18 65.8 20.2 7.3e-18 64.3 11.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_S8 PF00410.14 AET38458.1 - 3.4e-26 91.5 0.1 4.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 RepC PF06504.6 AET38458.1 - 0.14 11.0 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Replication protein C (RepC) zf-C2H2_4 PF13894.1 AET38459.1 - 2.8e-07 30.3 16.1 0.001 19.2 1.5 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AET38459.1 - 2.1e-05 24.5 19.4 0.00011 22.3 1.7 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET38459.1 - 0.0004 20.5 4.7 0.0004 20.5 3.3 4.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 AET38459.1 - 0.019 15.1 1.4 0.051 13.8 1.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 AET38459.1 - 3.5 7.8 8.6 17 5.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Arrestin_C PF02752.17 AET38460.1 - 4.6e-15 55.9 1.8 1.9e-14 53.8 1.3 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AET38460.1 - 6.2e-07 29.3 0.0 0.00014 21.7 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain F-box PF00646.28 AET38461.1 - 0.00029 20.4 4.3 0.00041 19.9 0.7 3.0 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 AET38461.1 - 0.00057 19.5 3.8 0.0018 17.9 2.7 1.9 1 0 0 1 1 1 1 F-box-like HSP70 PF00012.15 AET38462.1 - 2.5e-217 722.5 6.7 2.8e-217 722.3 4.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AET38462.1 - 2.6e-19 69.0 1.9 3.9e-16 58.5 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 AET38462.1 - 2.8e-07 30.3 0.0 6.8e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 AET38462.1 - 0.004 16.5 0.1 0.14 11.4 0.0 2.5 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 AET38462.1 - 0.0068 15.3 0.9 0.22 10.4 0.1 2.5 1 1 1 2 2 2 1 StbA protein FtsA PF14450.1 AET38462.1 - 0.05 13.4 7.6 38 4.1 5.3 3.9 1 1 0 1 1 1 0 Cell division protein FtsA P21-Arc PF04062.9 AET38463.1 - 1.6e-77 259.1 0.0 1.8e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CNH PF00780.17 AET38464.1 - 2.7e-76 256.6 0.2 2.7e-76 256.6 0.2 1.5 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 AET38464.1 - 5.8e-35 120.1 0.0 5.8e-35 120.1 0.0 2.9 2 1 1 3 3 3 1 Pleckstrin homology domain RhoGEF PF00621.15 AET38464.1 - 8.4e-33 113.7 0.1 8.4e-33 113.7 0.1 2.7 2 1 1 3 3 3 1 RhoGEF domain DEP PF00610.16 AET38464.1 - 3.6e-13 49.0 1.8 4.1e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ELO PF01151.13 AET38465.1 - 1.4e-61 207.9 21.1 1.8e-61 207.6 14.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family zf-BED PF02892.10 AET38466.1 - 4.7e-05 23.0 9.3 0.00013 21.6 6.4 1.8 1 0 0 1 1 1 1 BED zinc finger Crystallin PF00525.13 AET38466.1 - 0.015 15.4 0.2 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Alpha crystallin A chain, N terminal Menin PF05053.8 AET38466.1 - 7 4.6 8.1 9 4.3 4.0 1.9 2 0 0 2 2 2 0 Menin zf-C2H2_6 PF13912.1 AET38467.1 - 0.00024 20.9 11.1 0.00089 19.0 0.6 4.3 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AET38467.1 - 0.00099 19.3 2.8 0.00099 19.3 2.0 6.1 5 1 0 5 5 5 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET38467.1 - 0.0013 18.9 1.6 0.0013 18.9 1.1 5.8 5 1 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AET38467.1 - 0.0029 17.8 0.6 0.0029 17.8 0.4 5.6 4 1 1 5 5 5 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AET38467.1 - 0.0063 16.6 0.1 0.0063 16.6 0.1 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 AET38467.1 - 1.5 8.5 11.7 0.79 9.4 0.8 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FA_desaturase PF00487.19 AET38468.1 - 2.6e-21 76.2 26.2 4.6e-21 75.4 18.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 AET38468.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) KRE9 PF05390.6 AET38469.1 - 6.7e-39 132.5 4.7 1.5e-38 131.4 3.3 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 AET38469.1 - 3.2e-05 24.3 0.9 7.1e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family La PF05383.12 AET38470.1 - 7e-23 80.2 0.1 3.6e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 La domain BRAP2 PF07576.7 AET38470.1 - 0.001 18.6 0.2 0.002 17.6 0.1 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 RRM_6 PF14259.1 AET38470.1 - 0.0018 18.2 0.3 0.0051 16.7 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NPCBM PF08305.6 AET38470.1 - 0.028 14.3 0.2 0.2 11.5 0.0 2.1 1 1 1 2 2 2 0 NPCBM/NEW2 domain Acyltransferase PF01553.16 AET38472.1 - 6.9e-34 116.1 0.0 1e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase FBPase PF00316.15 AET38473.1 - 2.9e-133 443.7 0.0 3.2e-133 443.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase MFS_1 PF07690.11 AET38475.1 - 3e-10 39.3 37.3 6.8e-07 28.3 10.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SecY PF00344.15 AET38476.1 - 5.1e-88 295.2 14.9 6.3e-88 294.9 10.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AET38476.1 - 1.3e-18 66.1 0.6 5.7e-18 64.1 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p Glyco_hydro_85 PF03644.8 AET38477.1 - 1.5e-75 254.2 2.6 2e-75 253.8 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF553 PF04473.7 AET38478.1 - 0.058 12.6 0.1 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like domain Transp_cyt_pur PF02133.10 AET38479.1 - 4.6e-151 503.3 34.8 5.4e-151 503.0 24.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NTP_transferase PF00483.18 AET38480.1 - 5e-48 163.5 0.0 6.8e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AET38480.1 - 1.7e-10 41.1 0.0 2.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 AET38480.1 - 3.2e-10 39.0 16.7 3.9e-07 29.2 1.3 3.8 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) IspD PF01128.14 AET38480.1 - 0.094 12.2 0.0 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 AET38480.1 - 0.11 12.0 9.0 0.07 12.6 1.2 3.4 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase Ank_4 PF13637.1 AET38481.1 - 3.7e-18 65.5 0.6 1.4e-07 31.8 0.1 4.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AET38481.1 - 4.2e-17 62.2 0.2 1e-08 35.3 0.1 3.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AET38481.1 - 1.5e-15 56.0 1.0 1.3e-05 24.7 0.2 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 AET38481.1 - 4.2e-14 52.2 0.7 6.2e-06 26.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET38481.1 - 1.3e-10 40.4 0.7 0.0015 18.5 0.2 4.1 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 AET38481.1 - 2.9e-07 30.0 1.7 8.5e-07 28.5 0.1 2.6 2 1 0 2 2 2 1 KilA-N domain TFIID_20kDa PF03847.8 AET38481.1 - 0.018 15.3 2.8 1.7 9.0 0.0 3.6 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A Baculo_PEP_C PF04513.7 AET38481.1 - 0.11 12.2 6.4 0.049 13.4 0.9 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Y_phosphatase3 PF13350.1 AET38482.1 - 2e-26 93.2 0.0 4.1e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_5 PF12695.2 AET38482.1 - 7.4e-13 48.4 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AET38482.1 - 8.1e-10 38.9 0.0 4.3e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AET38482.1 - 1.6e-06 27.8 0.1 5.5e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Y_phosphatase3C PF13348.1 AET38482.1 - 8.6e-06 25.7 0.0 2.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 AET38482.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family DHBP_synthase PF00926.14 AET38483.1 - 7.5e-77 256.9 0.1 8.4e-77 256.7 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase tRNA-synt_1b PF00579.20 AET38484.1 - 3.8e-17 62.3 0.0 2.5e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Aha1_N PF09229.6 AET38484.1 - 0.039 13.7 0.3 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Snf7 PF03357.16 AET38485.1 - 1e-36 125.8 18.7 1.3e-36 125.5 13.0 1.1 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 AET38485.1 - 0.0042 17.1 7.0 0.0042 17.1 4.9 2.3 1 1 1 2 2 2 1 YlqD protein Cep57_MT_bd PF06657.8 AET38485.1 - 0.012 15.5 2.9 0.012 15.5 2.0 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Seryl_tRNA_N PF02403.17 AET38485.1 - 0.075 13.0 12.2 1.3 9.1 2.7 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 AET38485.1 - 0.1 12.4 15.0 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 AET38485.1 - 0.2 10.5 12.4 0.32 9.9 8.6 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 AET38485.1 - 0.98 7.7 7.5 1.3 7.3 5.2 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 AET38485.1 - 1.5 7.9 10.7 1.9 7.5 7.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliJ PF02050.11 AET38485.1 - 2 8.5 19.4 0.19 11.7 5.7 2.7 1 1 2 3 3 3 0 Flagellar FliJ protein Prefoldin PF02996.12 AET38485.1 - 2.4 7.8 11.9 0.36 10.5 0.3 3.4 2 1 1 3 3 3 0 Prefoldin subunit DUF1664 PF07889.7 AET38485.1 - 7.8 6.3 10.3 0.92 9.3 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 AET38485.1 - 8.5 6.4 15.8 3.1 7.9 1.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Methyltransf_23 PF13489.1 AET38486.1 - 2.5e-21 76.0 0.0 3.7e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET38486.1 - 1e-14 54.3 0.0 1.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AET38486.1 - 3.8e-13 49.7 0.0 9.7e-13 48.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET38486.1 - 1.7e-12 47.8 0.0 4.4e-12 46.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AET38486.1 - 3.1e-12 46.8 0.0 7.1e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AET38486.1 - 3.3e-07 29.7 0.0 4.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 AET38486.1 - 8.5e-07 28.3 0.0 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 AET38486.1 - 1.5e-06 27.2 0.0 2.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 AET38486.1 - 2.3e-06 27.1 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 AET38486.1 - 8.3e-06 25.2 0.0 1.9e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AET38486.1 - 2.6e-05 24.2 0.0 0.00059 19.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET38486.1 - 3.6e-05 24.0 0.0 7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AET38486.1 - 0.0018 17.6 0.4 0.0055 16.0 0.0 1.9 2 1 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 AET38486.1 - 0.0037 16.9 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AET38486.1 - 0.01 14.9 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase YL1 PF05764.8 AET38487.1 - 1.3e-52 178.8 29.9 1.3e-52 178.8 20.7 2.9 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 AET38487.1 - 1.7e-10 40.2 0.1 3.6e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RNase_P_p30 PF01876.11 AET38487.1 - 0.03 13.5 0.1 0.07 12.3 0.1 1.6 1 0 0 1 1 1 0 RNase P subunit p30 DUF3708 PF12501.3 AET38487.1 - 1.9 8.3 3.4 5 6.9 0.1 2.3 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter UvrD_C PF13361.1 AET38488.1 - 1.3e-47 162.9 0.8 1.3e-47 162.9 0.6 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 AET38488.1 - 4.8e-34 118.0 0.6 5e-18 65.4 0.0 3.0 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 AET38488.1 - 1.6e-10 41.0 0.0 5.4e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 AET38488.1 - 2.8e-10 39.7 0.0 6.3e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 AET38488.1 - 1.1e-07 31.6 0.0 5.7e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 AET38488.1 - 1.3e-07 31.3 0.0 0.067 12.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 AET38488.1 - 4.4e-05 22.9 0.1 0.011 15.0 0.0 3.6 2 2 1 3 3 3 1 AAA domain AAA_30 PF13604.1 AET38488.1 - 0.019 14.5 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Vps52 PF04129.7 AET38489.1 - 2.5e-134 448.6 14.8 3.3e-134 448.2 10.3 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Rep_fac_C PF08542.6 AET38490.1 - 1.1e-21 76.6 0.9 9.8e-21 73.5 0.1 2.7 3 0 0 3 3 3 1 Replication factor C C-terminal domain AAA PF00004.24 AET38490.1 - 9.7e-14 51.6 0.0 1.9e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AET38490.1 - 2.5e-13 49.9 0.1 3.1e-11 43.2 0.1 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 AET38490.1 - 4.2e-07 29.9 0.0 1.1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 AET38490.1 - 4.4e-07 28.9 0.0 0.0026 16.5 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 AET38490.1 - 2.7e-06 26.6 0.0 1.4e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AET38490.1 - 3.5e-06 27.1 0.0 8.5e-05 22.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AET38490.1 - 4.6e-06 26.8 0.5 0.055 13.6 0.1 2.9 2 2 1 3 3 3 2 AAA domain AAA_3 PF07726.6 AET38490.1 - 1.6e-05 24.4 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 AET38490.1 - 4.3e-05 23.1 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 AET38490.1 - 0.00037 20.0 0.0 0.038 13.4 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 AET38490.1 - 0.00064 18.9 0.0 0.0085 15.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AET38490.1 - 0.002 17.8 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 AET38490.1 - 0.003 17.2 0.7 0.053 13.2 0.0 2.6 2 1 1 3 3 3 1 NTPase DNA_pol3_delta PF06144.8 AET38490.1 - 0.009 15.5 0.3 0.015 14.7 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 AET38490.1 - 0.0093 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family ArgK PF03308.11 AET38490.1 - 0.016 14.0 0.0 0.16 10.7 0.0 2.2 1 1 1 2 2 2 0 ArgK protein DEAD PF00270.24 AET38490.1 - 0.029 13.8 0.1 0.45 9.9 0.0 2.5 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.1 AET38490.1 - 0.034 13.7 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3650 PF12368.3 AET38490.1 - 0.21 11.0 1.1 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) tRNA_m1G_MT PF01746.16 AET38491.1 - 2e-40 138.4 0.2 3.2e-40 137.7 0.1 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase PQ-loop PF04193.9 AET38492.1 - 3e-43 145.1 12.0 7.2e-24 83.1 0.6 2.9 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 AET38492.1 - 0.041 13.7 9.8 1.5 8.7 0.2 3.5 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange DUF4234 PF14018.1 AET38492.1 - 1.2 8.9 6.2 1 9.1 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Reo_sigmaC PF04582.7 AET38493.1 - 0.77 8.8 13.7 0.17 11.0 1.8 3.2 2 1 1 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 AET38493.1 - 5.1 7.4 18.7 9.3 6.5 0.2 5.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 AET38493.1 - 5.1 6.8 48.9 0.5 10.1 4.5 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) MutS_V PF00488.16 AET38494.1 - 5.1e-96 320.6 0.1 9.5e-96 319.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AET38494.1 - 7.3e-34 117.3 1.7 7.3e-34 117.3 1.2 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 AET38494.1 - 2.3e-17 62.9 1.1 2.3e-17 62.9 0.7 2.7 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.12 AET38494.1 - 8.7e-17 61.4 0.1 2.9e-16 59.7 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 AET38494.1 - 2.2e-07 30.8 0.0 7.6e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain I Peptidase_M16 PF00675.15 AET38494.1 - 0.05 13.3 0.1 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Sugar_tr PF00083.19 AET38495.1 - 5.5e-119 397.6 39.2 6.3e-119 397.5 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET38495.1 - 2.6e-19 69.1 42.2 7.1e-18 64.4 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sod_Fe_C PF02777.13 AET38496.1 - 6.5e-37 125.6 0.1 1.2e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AET38496.1 - 1.6e-25 89.1 0.7 2.7e-25 88.4 0.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.2 AET38496.1 - 0.087 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PWWP PF00855.12 AET38499.1 - 1.7e-15 56.9 0.1 4.3e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 PWWP domain DUF4588 PF15251.1 AET38499.1 - 0.15 11.9 9.1 0.23 11.4 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) SR-25 PF10500.4 AET38499.1 - 0.56 9.6 13.7 1 8.7 9.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pyridox_oxidase PF01243.15 AET38500.1 - 3.7e-15 55.6 0.0 8.8e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 AET38500.1 - 0.00042 20.1 0.1 0.00087 19.0 0.1 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AET38500.1 - 0.0014 18.5 0.0 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase AAA PF00004.24 AET38501.1 - 6.1e-44 149.4 0.0 1.1e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 AET38501.1 - 1e-30 105.4 0.0 1.3e-29 101.8 0.2 2.5 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 AET38501.1 - 3.8e-21 74.7 1.6 1.3e-20 73.0 0.8 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 AET38501.1 - 1.7e-06 28.2 0.1 0.0069 16.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 AET38501.1 - 3.7e-06 27.7 0.3 1.9e-05 25.4 0.0 2.3 3 1 1 4 4 1 1 AAA domain RuvB_N PF05496.7 AET38501.1 - 8.8e-06 24.9 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AET38501.1 - 1.2e-05 25.2 0.1 4.3e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AET38501.1 - 1.3e-05 24.8 0.0 6e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AET38501.1 - 2.5e-05 23.7 0.0 5.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 AET38501.1 - 3.2e-05 24.0 0.0 0.00022 21.2 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 AET38501.1 - 5.3e-05 22.7 0.1 0.039 13.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain RNA_helicase PF00910.17 AET38501.1 - 7.2e-05 22.9 0.1 0.0075 16.4 0.0 3.1 3 0 0 3 3 3 1 RNA helicase DUF815 PF05673.8 AET38501.1 - 7.6e-05 21.7 0.0 0.00029 19.8 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.8 AET38501.1 - 0.00011 21.0 0.0 0.00018 20.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 AET38501.1 - 0.00059 19.7 0.0 0.0015 18.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 AET38501.1 - 0.00079 19.3 0.0 0.0019 18.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 AET38501.1 - 0.006 16.8 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AET38501.1 - 0.0061 15.7 0.0 1.8 7.5 0.0 2.2 1 1 1 2 2 2 1 KaiC Zeta_toxin PF06414.7 AET38501.1 - 0.0068 15.5 0.1 0.14 11.2 0.0 2.3 1 1 1 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 AET38501.1 - 0.009 15.7 0.0 0.45 10.1 0.0 2.5 1 1 1 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 AET38501.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AET38501.1 - 0.02 14.6 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 AET38501.1 - 0.029 13.5 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 AET38501.1 - 0.037 13.9 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 AET38501.1 - 0.04 13.1 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 AET38501.1 - 0.063 12.9 0.0 0.6 9.7 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 AET38501.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 AET38501.1 - 0.081 12.3 0.0 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 AET38501.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 AET38501.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 AET38501.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CPT PF07931.7 AET38501.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NBP1 PF08537.5 AET38502.1 - 6.2e-92 308.2 25.0 7.4e-92 307.9 17.3 1.1 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 Pox_VERT_large PF04441.8 AET38502.1 - 0.039 12.1 0.1 0.054 11.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit DNA_pol_E_B PF04042.11 AET38503.1 - 1.7e-41 141.8 2.3 2.8e-41 141.0 1.6 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B S1_2 PF13509.1 AET38503.1 - 0.053 13.4 0.2 14 5.6 0.0 2.9 3 0 0 3 3 3 0 S1 domain Prenyltrans PF00432.16 AET38504.1 - 1.7e-62 206.6 4.7 5.2e-13 48.3 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AET38504.1 - 2.6e-35 121.2 0.0 2.2e-14 53.8 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 AET38504.1 - 3e-09 36.8 0.0 0.0002 21.3 0.0 3.2 1 1 2 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 AET38504.1 - 0.00032 20.0 0.0 0.17 11.0 0.0 3.5 3 1 1 4 4 4 1 A-macroglobulin complement component WD40 PF00400.27 AET38505.1 - 4.4e-47 156.3 13.6 1.1e-11 44.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 AET38505.1 - 6.6e-05 22.7 0.0 0.03 14.0 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 AET38505.1 - 0.00014 20.2 0.0 0.31 9.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain HDA2-3 PF11496.3 AET38506.1 - 2.9e-91 305.3 0.8 2.9e-91 305.3 0.6 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_13 PF13166.1 AET38506.1 - 0.043 12.2 20.3 0.066 11.6 14.0 1.2 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 AET38506.1 - 0.74 8.9 3.7 1.9 7.5 1.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 AET38506.1 - 3.6 7.3 8.2 0.84 9.4 1.7 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec23_trunk PF04811.10 AET38507.1 - 2.2e-73 246.6 0.0 2.9e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AET38507.1 - 5e-35 119.0 0.0 9.3e-35 118.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AET38507.1 - 2.4e-28 98.4 0.0 4.3e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AET38507.1 - 4.2e-15 55.0 3.9 7.3e-15 54.2 2.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AET38507.1 - 2e-11 43.4 0.0 3.9e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat MHC_I PF00129.13 AET38507.1 - 0.062 12.6 0.0 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 PIG-U PF06728.8 AET38508.1 - 5.9e-101 338.0 42.8 7.7e-101 337.7 29.7 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U LSM PF01423.17 AET38509.1 - 1.9e-14 52.9 0.4 2.2e-14 52.7 0.3 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M26_C PF07580.9 AET38509.1 - 0.086 11.1 0.0 0.1 10.8 0.0 1.0 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Glycos_transf_2 PF00535.21 AET38510.1 - 1.2e-31 109.7 0.0 1.5e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AET38510.1 - 1e-10 41.7 0.0 1.4e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AET38510.1 - 8.1e-08 31.6 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 hDGE_amylase PF14701.1 AET38511.1 - 5.9e-164 545.9 0.3 8.2e-164 545.4 0.2 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 AET38511.1 - 2.7e-114 381.7 0.0 3.9e-114 381.2 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 AET38511.1 - 7.1e-68 228.5 0.0 1.2e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 AET38511.1 - 5.2e-20 71.0 0.0 1.3e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 AET38511.1 - 7.2e-09 35.4 0.2 3e-06 26.8 0.2 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain ATG13 PF10033.4 AET38512.1 - 3.6e-66 222.9 0.2 5.9e-66 222.2 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 zf-C2H2 PF00096.21 AET38513.1 - 1e-29 101.0 56.4 7.5e-05 22.8 0.3 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET38513.1 - 1.4e-20 72.0 52.6 0.001 19.2 2.8 9.3 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AET38513.1 - 1.2e-14 53.7 61.6 0.00015 21.9 0.1 10.0 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AET38513.1 - 3.4e-07 30.2 33.9 0.23 11.6 0.5 8.6 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AET38513.1 - 3.2e-06 27.1 36.6 0.18 12.0 0.2 9.0 9 0 0 9 9 9 6 Zinc-finger of C2H2 type RNA_pol_Rpb6 PF01192.17 AET38514.1 - 3.5e-23 81.1 0.2 5e-23 80.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 EF-hand_6 PF13405.1 AET38515.1 - 3.8e-06 26.3 3.7 0.00058 19.5 0.1 3.9 3 2 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 AET38515.1 - 3.6e-05 23.7 0.7 9.2e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AET38515.1 - 7.8e-05 21.7 4.0 0.00076 18.6 0.2 3.8 3 2 2 5 5 5 1 EF hand EF-hand_5 PF13202.1 AET38515.1 - 9e-05 21.6 2.6 9e-05 21.6 1.8 2.3 2 0 0 2 2 2 1 EF hand DUF1877 PF08974.5 AET38515.1 - 0.0012 18.5 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) EF-hand_8 PF13833.1 AET38515.1 - 0.032 13.8 1.9 0.8 9.3 0.1 3.1 1 1 2 3 3 3 0 EF-hand domain pair B5 PF03484.10 AET38515.1 - 0.11 12.3 0.2 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetase B5 domain TPR_11 PF13414.1 AET38516.1 - 1.4e-28 98.2 18.8 9.3e-05 21.9 0.1 10.8 6 4 5 11 11 11 8 TPR repeat TPR_16 PF13432.1 AET38516.1 - 2.2e-28 98.2 0.8 0.00032 21.2 0.0 10.1 8 2 2 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 AET38516.1 - 1.4e-24 86.1 5.9 4.7e-06 26.8 0.0 8.5 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 AET38516.1 - 1.7e-22 77.8 0.7 0.0015 18.9 0.0 11.1 7 2 4 11 11 11 3 Tetratricopeptide repeat TPR_2 PF07719.12 AET38516.1 - 5.1e-21 72.8 19.8 0.00014 21.5 0.0 12.9 15 0 0 15 15 11 4 Tetratricopeptide repeat TPR_1 PF00515.23 AET38516.1 - 4.7e-18 63.9 19.6 3.1e-05 23.3 0.0 11.6 13 1 0 13 13 13 4 Tetratricopeptide repeat TPR_17 PF13431.1 AET38516.1 - 1e-17 62.7 10.5 0.011 15.8 0.0 11.1 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_6 PF13174.1 AET38516.1 - 8.2e-15 54.1 0.1 0.042 14.2 0.0 9.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 AET38516.1 - 7.5e-12 44.1 3.9 0.0016 18.0 0.0 7.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 AET38516.1 - 9.8e-12 44.6 6.2 0.0044 16.9 0.0 7.5 4 3 4 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 AET38516.1 - 2e-08 34.2 12.4 2.7e-05 24.1 0.1 6.0 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AET38516.1 - 1.8e-07 30.4 0.1 2.5 8.1 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.1 AET38516.1 - 0.00054 20.0 3.2 3.5 7.8 0.0 5.9 5 3 2 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 AET38516.1 - 0.012 15.4 0.3 5.1 7.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.2 AET38516.1 - 0.022 14.7 0.3 0.42 10.6 0.0 3.1 3 0 0 3 3 3 0 Tetratrico peptide repeat BTAD PF03704.12 AET38516.1 - 0.037 14.3 0.1 4.8 7.4 0.0 3.7 4 0 0 4 4 3 0 Bacterial transcriptional activator domain RNA_pol_Rpc82 PF05645.8 AET38517.1 - 2e-62 211.0 0.2 3.7e-62 210.2 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 AET38517.1 - 2.5e-23 81.7 1.5 1.3e-19 69.8 0.1 3.4 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 AET38517.1 - 3e-08 33.1 0.1 0.0082 15.6 0.0 2.7 2 0 0 2 2 2 2 TFIIE alpha subunit Rio2_N PF09202.6 AET38517.1 - 0.035 14.1 0.5 1.1 9.3 0.0 2.9 2 0 0 2 2 2 0 Rio2, N-terminal Peptidase_M16 PF00675.15 AET38518.1 - 7e-24 84.2 0.0 1.2e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AET38518.1 - 7e-11 42.1 0.1 3.9e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain PTR2 PF00854.16 AET38519.1 - 8.9e-36 123.4 3.8 5.9e-35 120.7 2.7 2.0 1 1 0 1 1 1 1 POT family Fungal_trans_2 PF11951.3 AET38520.1 - 2.3e-11 42.9 2.3 4e-11 42.1 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET38520.1 - 2.8e-09 36.7 11.6 5.1e-09 35.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF917 PF06032.7 AET38521.1 - 3.4e-103 344.8 0.0 5.7e-103 344.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 AET38521.1 - 4.1e-46 157.3 1.6 1.5e-44 152.2 0.9 2.6 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 AET38521.1 - 6.8e-32 110.3 1.5 1.1e-30 106.4 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 AET38521.1 - 0.039 12.2 0.1 0.38 9.0 0.0 2.1 2 0 0 2 2 2 0 MutL protein RrnaAD PF00398.15 AET38522.1 - 9.6e-65 218.1 0.0 1.2e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AET38522.1 - 2e-10 40.7 0.0 3.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET38522.1 - 1.4e-06 28.8 0.0 3.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AET38522.1 - 7.2e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 AET38522.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AET38522.1 - 0.00037 19.9 0.0 0.00076 18.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Met_10 PF02475.11 AET38522.1 - 0.00053 19.6 0.0 0.00085 18.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.7 AET38522.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AET38522.1 - 0.0019 17.3 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 AET38522.1 - 0.0026 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 AET38522.1 - 0.0049 16.0 0.0 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_25 PF13649.1 AET38522.1 - 0.028 14.7 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.11 AET38522.1 - 0.03 13.2 0.0 0.058 12.2 0.0 1.5 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.13 AET38522.1 - 0.052 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 AET38522.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase UPF0020 PF01170.13 AET38522.1 - 0.12 11.8 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PI-PLC-X PF00388.14 AET38524.1 - 4.1e-48 162.4 0.0 8e-48 161.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AET38524.1 - 3.3e-37 127.0 0.1 7e-37 126.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.1 AET38524.1 - 7.2e-05 22.8 3.6 0.0046 17.0 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.1 AET38524.1 - 0.0003 20.3 0.2 0.0012 18.5 0.2 2.1 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 AET38524.1 - 0.00048 19.2 0.1 0.0016 17.6 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_like PF09279.6 AET38524.1 - 0.00056 19.8 0.9 0.0076 16.2 0.0 2.8 2 1 1 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 AET38524.1 - 0.0015 18.3 0.1 0.016 15.0 0.0 2.7 3 0 0 3 3 3 1 C2 domain EF-hand_6 PF13405.1 AET38524.1 - 0.026 14.3 0.3 0.026 14.3 0.2 2.3 2 0 0 2 2 1 0 EF-hand domain EF-hand_8 PF13833.1 AET38524.1 - 0.058 13.0 0.1 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 AET38524.1 - 0.12 11.7 0.5 0.32 10.3 0.4 1.7 1 0 0 1 1 1 0 EF hand G6B PF15096.1 AET38524.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 G6B family KAR9 PF08580.5 AET38525.1 - 1.8e-138 462.8 31.2 2.2e-138 462.5 21.6 1.0 1 0 0 1 1 1 1 Yeast cortical protein KAR9 ABC_membrane PF00664.18 AET38526.1 - 7.6e-52 176.4 5.2 1e-51 175.9 3.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AET38526.1 - 1.1e-35 122.8 0.0 9e-35 119.9 0.0 2.5 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.14 AET38526.1 - 0.00035 19.8 0.0 0.029 13.6 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AET38526.1 - 0.0014 18.6 0.4 1.4 8.8 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 AET38526.1 - 0.0016 18.4 0.0 0.005 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 AET38526.1 - 0.0017 17.7 0.1 0.13 11.6 0.0 3.2 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.1 AET38526.1 - 0.002 17.6 0.3 0.013 14.9 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_5 PF07728.9 AET38526.1 - 0.0058 16.3 0.1 0.057 13.1 0.0 2.7 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 AET38526.1 - 0.0059 16.0 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 AET38526.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 AET38526.1 - 0.019 15.3 0.2 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AET38526.1 - 0.02 15.6 0.0 0.056 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 AET38526.1 - 0.024 13.2 0.1 0.058 11.9 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.1 AET38526.1 - 0.044 13.1 0.0 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AET38526.1 - 0.045 13.9 0.2 0.77 9.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain Peptidase_C58 PF03543.9 AET38526.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen ATP-synt_Eps PF04627.8 AET38527.1 - 8.3e-21 73.2 2.1 9.7e-21 73.0 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DNA_pol_phi PF04931.8 AET38528.1 - 7.4e-92 308.4 31.0 6.4e-52 176.3 11.5 2.7 2 1 0 2 2 2 2 DNA polymerase phi WD40 PF00400.27 AET38531.1 - 9.4e-26 88.7 0.2 1.9e-06 27.4 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AET38531.1 - 1.4e-23 82.5 0.3 3.1e-23 81.4 0.2 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Arg_repressor_C PF02863.13 AET38531.1 - 0.069 12.6 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain PGM_PMM_I PF02878.11 AET38532.1 - 1.1e-16 60.5 0.0 4.1e-08 32.8 0.0 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AET38532.1 - 2.2e-10 40.7 0.0 6.8e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AET38532.1 - 7.7e-09 35.4 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Mitochondr_Som1 PF11093.3 AET38533.1 - 1.3e-22 79.4 0.9 1.6e-22 79.0 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Lyase_1 PF00206.15 AET38534.1 - 2.9e-114 381.4 0.0 4.1e-114 380.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 AET38534.1 - 6.1e-24 83.8 0.0 1.6e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Peptidase_S8 PF00082.17 AET38535.1 - 2.4e-54 184.4 9.6 3.1e-54 184.0 6.6 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AET38535.1 - 7.2e-05 23.2 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Fcf1 PF04900.7 AET38536.1 - 7.9e-32 109.3 0.9 1.5e-31 108.4 0.6 1.5 1 0 0 1 1 1 1 Fcf1 Kinesin PF00225.18 AET38537.1 - 1.3e-97 326.5 6.1 1.3e-97 326.5 4.2 3.8 3 1 0 3 3 3 1 Kinesin motor domain Hpt PF01627.18 AET38537.1 - 0.052 13.5 1.7 1.5 8.8 0.0 3.6 4 0 0 4 4 4 0 Hpt domain NPR2 PF06218.6 AET38538.1 - 3.9e-171 569.4 5.8 3.9e-171 569.4 4.0 1.8 2 0 0 2 2 2 1 Nitrogen permease regulator 2 NPR3 PF03666.8 AET38538.1 - 0.00039 19.0 2.3 0.003 16.1 0.0 2.7 3 0 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 DUF367 PF04034.8 AET38539.1 - 7.5e-54 180.7 0.0 1.1e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 AET38539.1 - 2.2e-14 52.7 0.2 4.8e-14 51.6 0.2 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VPS9 PF02204.13 AET38540.1 - 2.2e-17 62.9 0.6 1.4e-15 57.1 0.0 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 AET38540.1 - 7.2e-09 35.6 0.2 0.005 17.0 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 AET38540.1 - 4.8e-07 30.0 0.2 0.00042 20.5 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AET38540.1 - 4e-05 23.2 0.0 0.013 15.3 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 AET38540.1 - 0.0034 17.8 2.7 4 8.0 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET38540.1 - 0.013 15.6 0.9 6.9 7.2 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat TPR_11 PF13414.1 AET38541.1 - 7.2e-27 92.8 4.5 8.1e-18 63.8 0.9 3.9 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 AET38541.1 - 1.5e-16 59.2 10.8 8.9e-07 28.2 0.1 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 AET38541.1 - 8.9e-15 53.3 11.4 5.1e-05 22.8 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 AET38541.1 - 7.6e-10 38.2 0.3 0.00015 21.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AET38541.1 - 8.9e-10 38.9 4.8 2.4e-05 24.8 0.6 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AET38541.1 - 1.8e-08 34.2 0.1 0.025 15.1 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AET38541.1 - 1.6e-07 31.1 0.8 1.4e-05 24.9 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 AET38541.1 - 1.2e-06 28.7 2.0 0.0099 16.2 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AET38541.1 - 1.7e-05 24.2 6.7 0.00042 19.9 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 AET38541.1 - 3e-05 24.3 0.7 0.0064 16.8 0.1 2.4 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_7 PF13176.1 AET38541.1 - 0.00029 20.3 0.4 0.57 10.1 0.1 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 AET38541.1 - 0.00049 20.3 1.1 0.028 14.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 AET38541.1 - 0.0011 18.7 0.0 0.012 15.4 0.0 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 AET38541.1 - 0.025 14.7 0.4 0.07 13.2 0.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 AET38541.1 - 0.14 12.1 0.8 7.4 6.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 AET38541.1 - 1.6 8.6 7.5 11 6.0 0.0 4.2 3 2 1 4 4 4 0 MIT (microtubule interacting and transport) domain HSCB_C PF07743.8 AET38541.1 - 8.3 6.9 7.2 22 5.6 1.2 2.9 3 0 0 3 3 2 0 HSCB C-terminal oligomerisation domain Alg6_Alg8 PF03155.10 AET38542.1 - 7.2e-151 503.1 31.8 8.6e-151 502.9 22.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ras PF00071.17 AET38543.1 - 7e-58 194.5 0.2 8.3e-58 194.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET38543.1 - 1.7e-19 70.4 0.0 2.8e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET38543.1 - 1.9e-15 56.5 0.0 2.2e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET38543.1 - 1.3e-08 34.3 0.1 1.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AET38543.1 - 2.1e-07 30.5 0.1 8.6e-06 25.3 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AET38543.1 - 6.1e-06 26.1 0.0 9.2e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AET38543.1 - 3.7e-05 23.0 0.0 5.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 AET38543.1 - 4.8e-05 23.5 0.0 8.7e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AET38543.1 - 0.00027 20.9 0.1 0.0099 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 AET38543.1 - 0.0018 18.0 0.1 0.0062 16.2 0.0 1.8 2 0 0 2 2 2 1 NTPase ATP_bind_1 PF03029.12 AET38543.1 - 0.0027 17.2 0.2 0.1 12.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 AET38543.1 - 0.0037 16.9 0.2 0.0062 16.2 0.2 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 AET38543.1 - 0.0045 16.6 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 AET38543.1 - 0.0045 16.4 0.1 0.014 14.8 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 AET38543.1 - 0.0069 15.5 0.1 0.015 14.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 AET38543.1 - 0.01 15.5 0.4 0.025 14.2 0.3 1.9 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 AET38543.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 AET38543.1 - 0.019 14.4 0.2 0.086 12.3 0.1 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 AET38543.1 - 0.022 13.6 0.1 0.13 11.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.13 AET38543.1 - 0.062 12.3 0.1 0.32 9.9 0.0 2.0 2 1 0 2 2 2 0 Septin AAA_10 PF12846.2 AET38543.1 - 0.081 12.3 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_35 PF14516.1 AET38543.1 - 0.1 11.2 0.0 0.28 9.7 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain Cyclin PF08613.6 AET38544.1 - 1.9e-32 112.7 1.6 1.9e-32 112.7 1.1 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 AET38544.1 - 0.002 17.7 0.2 0.0033 16.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DNA_pol_A_exo1 PF01612.15 AET38545.1 - 7e-48 162.4 1.5 1.2e-47 161.6 0.1 2.0 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 AET38545.1 - 2.4e-23 82.2 2.1 1.2e-21 76.8 0.7 2.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 AET38545.1 - 1.5e-11 43.8 0.0 3.2e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 HRDC domain HlyIII PF03006.15 AET38546.1 - 8e-51 172.5 21.4 9.7e-51 172.2 14.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF1772 PF08592.6 AET38546.1 - 0.29 10.8 2.5 0.24 11.1 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) zf-DHHC PF01529.15 AET38547.1 - 3.5e-30 104.6 17.2 3.5e-30 104.6 11.9 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase PAH PF02671.16 AET38548.1 - 1.4e-48 162.2 4.9 8.9e-19 66.8 0.4 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 AET38548.1 - 2.8e-43 145.7 0.2 1.1e-42 143.8 0.1 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Pkinase PF00069.20 AET38549.1 - 5.3e-73 245.3 0.0 9.5e-73 244.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38549.1 - 1.6e-39 135.5 0.0 2.5e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 AET38549.1 - 1.4e-33 114.6 0.2 5.4e-16 58.3 0.1 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 AET38549.1 - 2e-11 43.4 0.0 9.9e-11 41.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AET38549.1 - 0.00092 18.3 0.0 0.0022 17.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_3 PF08239.6 AET38549.1 - 0.0039 17.3 0.1 0.0081 16.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Topoisom_I_N PF02919.10 AET38550.1 - 1.2e-100 335.2 0.1 1.2e-100 335.2 0.1 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 AET38550.1 - 2.2e-86 288.7 0.5 2.2e-86 288.7 0.4 3.3 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 AET38550.1 - 9.1e-31 105.3 0.8 2.5e-30 103.9 0.5 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF2076 PF09849.4 AET38552.1 - 1.4e-05 25.2 7.0 1.6e-05 25.0 4.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 AET38552.1 - 2e-05 24.3 3.7 3.1e-05 23.7 2.6 1.3 1 0 0 1 1 1 1 CHCH domain Paramyxo_PNT PF13825.1 AET38552.1 - 2.3 7.3 5.1 1.6 7.8 2.8 1.3 1 1 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Herpes_BLLF1 PF05109.8 AET38552.1 - 7.4 4.3 9.9 9 4.1 6.8 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SAP PF02037.22 AET38553.1 - 5.1e-10 38.6 0.0 8.4e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain TRAPPC10 PF12584.3 AET38553.1 - 0.017 14.5 0.1 0.031 13.7 0.0 1.5 1 1 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 Packaging_FI PF14000.1 AET38553.1 - 0.074 13.2 0.3 0.074 13.2 0.2 2.0 2 0 0 2 2 2 0 DNA packaging protein FI GTP_EFTU PF00009.22 AET38553.1 - 0.12 11.7 0.4 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Polyketide_cyc PF03364.15 AET38554.1 - 6.4e-15 55.3 0.0 8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2404 PF10296.4 AET38555.1 - 0.00011 22.2 0.2 0.00056 19.9 0.1 2.2 1 1 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PX PF00787.19 AET38556.1 - 1.2e-19 70.1 0.1 3.4e-19 68.7 0.1 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 AET38556.1 - 0.00051 19.3 5.3 0.0008 18.7 3.7 1.3 1 0 0 1 1 1 1 Vps5 C terminal like DNase_II PF03265.10 AET38556.1 - 0.044 12.7 0.3 0.079 11.9 0.2 1.4 1 0 0 1 1 1 0 Deoxyribonuclease II Latarcin PF10279.4 AET38556.1 - 2.1 8.5 5.4 11 6.2 0.6 3.0 3 0 0 3 3 3 0 Latarcin precursor RTC PF01137.16 AET38557.1 - 3.7e-59 199.2 0.0 4.4e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 AET38557.1 - 1e-32 112.2 0.0 1.7e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain TAF4 PF05236.9 AET38558.1 - 5.2e-66 222.6 3.5 5.2e-66 222.6 2.4 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Suf PF05843.9 AET38558.1 - 0.039 13.6 1.6 0.062 13.0 1.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Histone PF00125.19 AET38559.1 - 1.5e-22 79.4 0.1 1.9e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AET38559.1 - 0.00013 21.9 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone OPA3 PF07047.7 AET38560.1 - 1e-32 112.6 1.4 1.2e-32 112.4 0.9 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HAUS5 PF14817.1 AET38560.1 - 0.0068 15.0 2.5 0.0068 15.0 1.7 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 5 HR1 PF02185.11 AET38560.1 - 0.033 13.9 2.0 0.046 13.4 0.9 1.7 1 1 0 1 1 1 0 Hr1 repeat NYD-SP28_assoc PF14775.1 AET38560.1 - 0.065 12.9 0.7 0.065 12.9 0.5 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain HAUS-augmin3 PF14932.1 AET38560.1 - 0.094 11.8 2.7 1.8 7.7 0.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Osmo_CC PF08946.5 AET38560.1 - 0.13 12.2 1.1 0.35 10.9 0.8 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DivIC PF04977.10 AET38560.1 - 0.28 10.7 2.7 0.74 9.3 1.2 2.2 2 1 0 2 2 2 0 Septum formation initiator zf-RING_2 PF13639.1 AET38561.1 - 6.3e-13 48.3 4.1 1.4e-12 47.2 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AET38561.1 - 1.2e-09 37.6 3.3 2.4e-09 36.7 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AET38561.1 - 5.4e-09 36.0 3.1 1.4e-08 34.7 2.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AET38561.1 - 2.9e-07 30.3 3.7 2.9e-07 30.3 2.6 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET38561.1 - 1.9e-06 27.4 3.7 1.9e-06 27.4 2.6 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AET38561.1 - 5.8e-06 25.8 5.4 5.8e-06 25.8 3.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AET38561.1 - 0.0017 18.0 4.2 0.0087 15.7 2.9 2.3 1 1 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 AET38561.1 - 0.012 15.5 2.7 0.039 13.9 1.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 AET38561.1 - 0.015 15.1 2.1 0.063 13.1 1.5 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 AET38561.1 - 0.015 14.7 0.1 0.059 12.9 0.1 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.2 AET38561.1 - 0.25 11.4 3.2 0.78 9.8 2.2 1.9 1 1 0 1 1 1 0 RING-variant domain Pox_A_type_inc PF04508.7 AET38561.1 - 0.46 10.3 7.4 0.11 12.3 2.5 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat zf-RING_4 PF14570.1 AET38561.1 - 0.63 9.6 4.3 1.3 8.6 3.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AET38561.1 - 0.86 9.5 4.2 0.65 9.9 0.8 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF605 PF04652.11 AET38561.1 - 4.5 6.5 35.3 7.5 5.8 24.5 1.3 1 0 0 1 1 1 0 Vta1 like DUF775 PF05603.7 AET38561.1 - 6.9 6.1 24.1 4.5 6.7 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DUF2072 PF09845.4 AET38561.1 - 9.6 6.1 12.0 3.9 7.4 0.5 2.5 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) RNA_pol_I_TF PF04090.7 AET38562.1 - 8e-66 221.1 0.7 1.4e-65 220.3 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor La PF05383.12 AET38563.1 - 9.1e-16 57.4 0.3 1.6e-15 56.5 0.2 1.4 1 0 0 1 1 1 1 La domain ABC1 PF03109.11 AET38564.1 - 1.8e-35 121.5 0.0 4e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Abhydrolase_8 PF06259.7 AET38564.1 - 0.048 13.1 0.1 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase OB_NTP_bind PF07717.11 AET38565.1 - 2.1e-27 95.2 0.0 5.3e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AET38565.1 - 2.6e-27 94.7 0.1 6.6e-27 93.5 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AET38565.1 - 8.1e-12 44.8 0.0 2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AET38565.1 - 1.6e-08 34.2 0.2 4.6e-08 32.7 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AET38565.1 - 7.1e-07 29.4 0.1 3.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.9 AET38565.1 - 0.00011 21.9 0.1 0.00027 20.7 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.17 AET38565.1 - 0.00032 20.1 0.1 0.00085 18.8 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 AET38565.1 - 0.00041 20.2 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_23 PF13476.1 AET38565.1 - 0.0045 17.3 0.0 0.032 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AET38565.1 - 0.0087 14.9 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 AET38565.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 AET38565.1 - 0.026 13.4 0.0 0.28 9.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 AET38565.1 - 0.078 12.4 0.1 14 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 AET38565.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain LSM PF01423.17 AET38566.1 - 0.0044 16.5 0.0 0.008 15.6 0.0 1.5 1 0 0 1 1 1 1 LSM domain Nab2 PF11517.3 AET38567.1 - 1e-47 160.6 1.4 1.7e-47 159.9 1.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 AET38567.1 - 2.3e-07 30.5 60.7 9.6e-06 25.4 3.5 6.6 6 1 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_S5 PF00333.15 AET38568.1 - 9e-29 99.0 3.3 9e-29 99.0 2.3 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AET38568.1 - 5.1e-21 73.7 0.0 8.7e-21 72.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain E3_binding PF02817.12 AET38568.1 - 0.13 11.9 1.1 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 e3 binding domain Tape_meas_lam_C PF09718.5 AET38569.1 - 0.0029 17.5 0.3 0.97 9.3 0.1 2.2 2 0 0 2 2 2 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF883 PF05957.8 AET38569.1 - 0.11 12.8 2.5 0.69 10.3 1.7 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) EspB PF05802.6 AET38569.1 - 0.3 9.9 3.7 0.78 8.6 2.5 1.6 1 1 0 1 1 1 0 Enterobacterial EspB protein MT0933_antitox PF14013.1 AET38569.1 - 7.4 6.7 8.4 55 3.9 4.1 2.7 1 1 1 2 2 2 0 MT0933-like antitoxin protein Mon1 PF03164.9 AET38570.1 - 4.9e-108 361.4 0.7 6.7e-108 360.9 0.5 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 GATA PF00320.22 AET38571.1 - 1.3e-09 37.2 4.3 1.3e-09 37.2 3.0 1.9 2 0 0 2 2 2 1 GATA zinc finger Glyco_hydro_31 PF01055.21 AET38572.1 - 1.1e-145 485.8 0.8 1.7e-145 485.2 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AET38572.1 - 2.5e-22 78.4 1.9 7.5e-22 76.9 0.3 2.6 3 0 0 3 3 3 1 Galactose mutarotase-like GIY-YIG PF01541.19 AET38573.1 - 5.9e-08 32.9 0.2 1.7e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 GIY-YIG catalytic domain DUF3090 PF11290.3 AET38573.1 - 0.055 12.9 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) DUF329 PF03884.9 AET38573.1 - 0.99 9.0 4.1 6.8 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-RING_2 PF13639.1 AET38573.1 - 1.6 8.5 8.1 3.1 7.6 5.6 1.5 1 0 0 1 1 1 0 Ring finger domain Methyltransf_11 PF08241.7 AET38574.1 - 0.0029 18.0 0.0 0.0071 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTHFR PF02219.12 AET38575.1 - 1.7e-116 388.3 0.0 2.3e-116 387.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Tyr-DNA_phospho PF06087.7 AET38576.1 - 1.3e-92 310.7 0.0 1.6e-92 310.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase AMP-binding PF00501.23 AET38577.1 - 3.7e-78 262.7 0.0 4.8e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AET38577.1 - 4.5e-13 49.9 0.3 1.3e-12 48.4 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Transket_pyr PF02779.19 AET38578.1 - 2.2e-46 157.5 0.1 4e-46 156.7 0.0 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AET38578.1 - 1.1e-34 119.0 0.0 2.3e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Acatn PF13000.2 AET38579.1 - 6.6e-211 701.5 22.4 7.5e-211 701.3 15.5 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Scs3p PF10261.4 AET38580.1 - 2.2e-69 233.1 10.9 3e-69 232.7 7.5 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Med31 PF05669.7 AET38581.1 - 4.5e-34 116.2 0.8 5.3e-34 116.0 0.5 1.1 1 0 0 1 1 1 1 SOH1 MF_alpha PF04648.7 AET38582.1 - 2.3e-17 62.0 16.8 1e-05 25.4 0.5 3.2 3 0 0 3 3 3 3 Yeast mating factor alpha hormone MF_alpha_N PF05436.6 AET38582.1 - 7.8e-17 60.7 0.4 9.6e-17 60.4 0.3 1.1 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus SH3_9 PF14604.1 AET38582.1 - 0.041 13.4 0.0 7.3 6.2 0.0 2.8 1 1 1 2 2 2 0 Variant SH3 domain CPSase_L_D2 PF02786.12 AET38583.1 - 1.9e-83 278.9 0.2 3e-83 278.2 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 AET38583.1 - 2.9e-65 219.4 0.0 5.2e-65 218.5 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 AET38583.1 - 1.5e-35 121.6 0.1 3.3e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AET38583.1 - 5.5e-29 100.3 0.0 1.6e-28 98.7 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 AET38583.1 - 2.2e-26 92.9 0.0 4.3e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 AET38583.1 - 7.8e-19 67.0 3.6 7.8e-19 67.0 2.5 2.2 3 0 0 3 3 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 AET38583.1 - 7.9e-18 64.2 0.1 3.5e-17 62.1 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 AET38583.1 - 4e-16 59.2 0.1 8.1e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AET38583.1 - 1.2e-07 31.3 0.0 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 AET38583.1 - 3.1e-07 29.9 4.0 0.0032 17.0 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 AET38583.1 - 4.5e-06 26.1 0.0 9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 AET38583.1 - 7.9e-06 25.4 0.0 2.8e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 AET38583.1 - 8.5e-05 22.4 0.0 0.00029 20.7 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AET38583.1 - 0.00071 19.1 0.0 0.0062 16.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 AET38583.1 - 0.014 15.7 1.1 2.6 8.4 0.0 2.9 2 0 0 2 2 2 0 HlyD family secretion protein DASH_Duo1 PF08651.5 AET38584.1 - 9.9e-26 89.1 0.4 9.9e-26 89.1 0.3 1.8 2 0 0 2 2 2 1 DASH complex subunit Duo1 DUF3160 PF11369.3 AET38584.1 - 0.027 12.8 0.3 0.035 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) AAA_23 PF13476.1 AET38584.1 - 0.055 13.7 2.2 0.076 13.3 1.5 1.3 1 0 0 1 1 1 0 AAA domain Med2 PF11214.3 AET38584.1 - 2.1 8.4 9.3 1.2e+02 2.8 6.4 2.3 1 1 0 1 1 1 0 Mediator complex subunit 2 APG12 PF04110.8 AET38585.1 - 1.2e-26 92.6 0.0 2.1e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Kinetochor_Ybp2 PF08568.5 AET38586.1 - 1.8e-124 416.3 13.3 2.1e-124 416.1 9.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HUN PF08729.5 AET38587.1 - 8e-14 51.2 0.1 8e-14 51.2 0.0 2.3 2 0 0 2 2 2 1 HPC2 and ubinuclein domain BCDHK_Adom3 PF10436.4 AET38588.1 - 6.3e-37 126.6 1.5 1.1e-36 125.7 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AET38588.1 - 4.9e-09 35.8 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AET38588.1 - 0.0041 16.7 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UQ_con PF00179.21 AET38589.1 - 1.2e-50 170.5 0.1 1.4e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AET38589.1 - 6.6e-06 25.9 0.0 8.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AET38589.1 - 0.027 14.3 0.3 0.076 12.9 0.2 1.8 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 AET38589.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 UEV domain Nucleoplasmin PF03066.10 AET38589.1 - 2.5 7.6 7.8 3.2 7.2 5.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin COX4 PF02936.9 AET38590.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV CBS PF00571.23 AET38591.1 - 2.8e-22 78.1 2.2 1.4e-06 28.0 0.0 5.4 5 0 0 5 5 5 5 CBS domain ASCH PF04266.9 AET38591.1 - 0.08 13.3 0.0 3.9 7.9 0.0 3.0 3 0 0 3 3 3 0 ASCH domain Pro-rich_19 PF15455.1 AET38591.1 - 0.11 11.4 2.4 0.23 10.4 1.7 1.4 1 0 0 1 1 1 0 Proline-rich 19 FA_desaturase PF00487.19 AET38592.1 - 1.4e-17 64.0 24.4 1.4e-17 64.0 16.9 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 AET38592.1 - 5e-15 55.0 0.0 1.2e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF308 PF03729.8 AET38592.1 - 6.1 6.9 10.2 0.21 11.5 1.7 2.6 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) NAD_binding_7 PF13241.1 AET38593.1 - 6.9e-26 90.5 0.0 1.4e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 AET38593.1 - 9e-13 46.9 0.1 1.5e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 AET38593.1 - 3.9e-11 42.0 0.2 8.7e-11 40.9 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal ThiF PF00899.16 AET38593.1 - 0.081 12.7 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 ThiF family 2-Hacid_dh_C PF02826.14 AET38593.1 - 0.086 11.9 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.17 AET38594.1 - 9.8e-40 134.0 0.0 1.5e-16 59.7 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET38594.1 - 1.4e-27 95.4 0.0 8.6e-11 41.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET38594.1 - 1.2e-17 63.4 0.0 5.9e-07 29.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AET38594.1 - 0.022 14.5 0.0 0.072 12.8 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AET38594.1 - 0.045 13.5 0.0 0.045 13.5 0.0 2.9 4 0 0 4 4 4 0 RNA binding motif AAA_23 PF13476.1 AET38595.1 - 0.047 14.0 3.4 0.057 13.7 2.4 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 AET38595.1 - 0.75 9.3 5.6 1.1 8.8 3.9 1.2 1 0 0 1 1 1 0 IncA protein Med28 PF11594.3 AET38595.1 - 4.1 7.6 13.3 5.9 7.1 4.4 2.4 1 1 1 2 2 2 0 Mediator complex subunit 28 Cornichon PF03311.9 AET38596.1 - 9.7e-50 167.9 9.0 1.1e-49 167.8 6.2 1.0 1 0 0 1 1 1 1 Cornichon protein SNF2_N PF00176.18 AET38597.1 - 7.6e-67 225.1 0.5 1.6e-66 224.1 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AET38597.1 - 5.1e-11 42.2 0.0 1.7e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 AET38597.1 - 3.6e-06 26.5 2.8 8.5e-06 25.4 1.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AET38597.1 - 1.1e-05 25.3 1.1 3.4e-05 23.7 0.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET38597.1 - 5.6e-05 22.8 3.2 0.00013 21.7 2.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AET38597.1 - 0.00014 21.4 3.0 0.00033 20.2 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AET38597.1 - 0.0003 20.3 2.7 0.00067 19.2 1.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AET38597.1 - 0.025 14.3 1.8 0.068 12.8 1.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Patched PF02460.13 AET38597.1 - 0.11 10.3 0.4 0.23 9.3 0.3 1.4 1 0 0 1 1 1 0 Patched family Prok-RING_4 PF14447.1 AET38597.1 - 0.13 11.8 1.9 0.46 10.0 1.3 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cellulase PF00150.13 AET38598.1 - 3.4e-12 46.1 0.0 6.9e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pex14_N PF04695.8 AET38599.1 - 0.55 10.2 3.4 0.51 10.3 1.7 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1708 PF08101.6 AET38600.1 - 8.9e-130 433.2 0.3 3.2e-129 431.4 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) G_glu_transpept PF01019.16 AET38601.1 - 5.2e-137 457.4 0.0 6.5e-137 457.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GTP_EFTU PF00009.22 AET38602.1 - 1.9e-61 206.8 0.6 2.5e-61 206.4 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AET38602.1 - 9.4e-27 93.0 0.1 2.5e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AET38602.1 - 5.7e-21 74.4 0.8 1.6e-20 73.0 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AET38602.1 - 2.8e-05 24.0 0.0 5.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 AET38602.1 - 0.00013 21.5 0.0 0.00031 20.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 AET38602.1 - 0.0017 18.8 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AET38602.1 - 0.02 14.3 0.7 5.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 AET38602.1 - 0.083 12.0 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding cobW PF02492.14 AET38602.1 - 0.25 10.7 1.2 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 AET38602.1 - 4.9 6.4 6.2 6.8 6.0 0.1 2.3 1 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-U1 PF06220.7 AET38603.1 - 3.2e-18 64.9 5.7 7e-18 63.8 3.9 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 AET38603.1 - 0.27 11.4 5.9 1.1 9.4 4.1 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ATP_sub_h PF10775.4 AET38604.1 - 8.8e-26 89.4 0.0 1.1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase complex subunit h ADIP PF11559.3 AET38605.1 - 0.0031 17.4 0.1 0.0031 17.4 0.1 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Angiomotin_C PF12240.3 AET38605.1 - 0.0079 15.7 0.1 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 Angiomotin C terminal Ribosomal_60s PF00428.14 AET38605.1 - 8.5 6.8 10.8 13 6.2 0.4 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ras PF00071.17 AET38606.1 - 1.1e-50 171.1 0.0 1.4e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET38606.1 - 5.9e-17 62.2 0.0 1.3e-16 61.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AET38606.1 - 1.8e-11 43.6 0.0 2.4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 AET38606.1 - 0.00081 19.5 0.1 0.0054 16.8 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 AET38606.1 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AET38606.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit KaiC PF06745.8 AET38606.1 - 0.02 14.0 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 KaiC Pox_A32 PF04665.7 AET38606.1 - 0.026 13.8 0.1 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 AET38606.1 - 0.041 14.0 0.2 0.16 12.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 AET38606.1 - 0.052 12.2 2.7 1.1 7.8 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 AET38606.1 - 0.07 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AET38606.1 - 0.14 11.8 0.1 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IF-2B PF01008.12 AET38607.1 - 3.7e-81 272.1 0.6 1.1e-80 270.6 0.4 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF2837 PF10997.3 AET38607.1 - 0.044 12.9 0.1 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2837) NAD_binding_10 PF13460.1 AET38608.1 - 7.7e-11 42.3 0.0 6.9e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 NADH(P)-binding 3Beta_HSD PF01073.14 AET38608.1 - 4.6e-06 25.5 0.0 1.1e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AET38608.1 - 2.2e-05 23.9 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 AET38608.1 - 0.0033 17.3 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 AET38608.1 - 0.0081 15.1 0.0 0.82 8.5 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein KR PF08659.5 AET38608.1 - 0.036 13.7 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 KR domain GTP_EFTU PF00009.22 AET38609.1 - 5.5e-47 159.6 0.0 1.1e-46 158.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 AET38609.1 - 4.6e-38 129.4 7.0 8.1e-38 128.6 4.8 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 AET38609.1 - 1.5e-17 63.2 0.0 3.4e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 AET38609.1 - 0.00018 21.4 0.0 0.00048 20.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 AET38609.1 - 0.00088 18.6 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.20 AET38609.1 - 0.0011 18.9 0.2 0.0065 16.5 0.1 2.3 1 1 1 2 2 2 2 Elongation factor Tu domain 2 SRPRB PF09439.5 AET38609.1 - 0.024 13.8 0.0 0.069 12.3 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_II PF14492.1 AET38609.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II Hus1 PF04005.7 AET38610.1 - 2.3e-26 92.4 0.0 5.3e-26 91.2 0.0 1.5 1 1 0 1 1 1 1 Hus1-like protein Aminotran_5 PF00266.14 AET38611.1 - 3.1e-31 108.4 0.0 3.9e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ribosomal_S30 PF04758.9 AET38612.1 - 2.9e-30 103.7 6.2 3.4e-30 103.5 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GCIP PF13324.1 AET38613.1 - 2.3e-07 30.3 1.0 3.5e-07 29.7 0.7 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DASH_Dad4 PF08650.5 AET38613.1 - 0.038 13.8 1.1 1.8 8.4 0.1 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad4 WH1 PF00568.18 AET38614.1 - 1.4e-31 108.4 0.0 2.1e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 AET38614.1 - 0.00071 19.0 0.2 0.0095 15.5 0.3 2.4 2 0 0 2 2 2 1 WH2 motif Glyco_hydro_18 PF00704.23 AET38615.1 - 1.9e-21 76.8 0.5 2.2e-19 70.1 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 CBM_19 PF03427.8 AET38615.1 - 5.1e-06 26.1 5.2 5.1e-06 26.1 3.6 3.2 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) Methyltransf_16 PF10294.4 AET38616.1 - 4.5e-13 49.0 0.0 4.6e-12 45.7 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 AET38616.1 - 0.00057 19.6 0.0 0.00092 18.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AET38616.1 - 0.045 14.2 0.0 0.074 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain ECH PF00378.15 AET38617.1 - 3.8e-15 55.6 0.0 5.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Syndecan PF01034.15 AET38617.1 - 0.0049 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain DUF1640 PF07798.6 AET38618.1 - 7.7e-06 26.0 2.1 1.1e-05 25.5 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) RF-1 PF00472.15 AET38619.1 - 2.7e-18 65.8 7.6 1.6e-17 63.3 5.3 2.0 1 1 0 1 1 1 1 RF-1 domain DUF2621 PF11084.3 AET38619.1 - 0.15 11.7 0.4 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Fungal_trans PF04082.13 AET38620.1 - 3.3e-17 62.2 3.5 7.3e-17 61.0 2.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET38620.1 - 1.9e-05 24.4 10.1 5e-05 23.1 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM107 PF14995.1 AET38620.1 - 0.045 13.8 1.0 0.11 12.6 0.7 1.6 1 0 0 1 1 1 0 Transmembrane protein CPSF73-100_C PF11718.3 AET38621.1 - 1e-62 211.3 1.4 1.8e-62 210.5 1.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 AET38621.1 - 3.7e-33 114.1 0.0 2.5e-32 111.4 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 AET38621.1 - 1.3e-16 60.8 0.6 2.2e-16 60.0 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AET38621.1 - 8.4e-12 45.0 0.6 3.8e-11 42.8 0.3 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 AET38621.1 - 8.7e-10 38.2 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 AET38621.1 - 3.6e-06 26.7 0.1 1.4e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain LSM PF01423.17 AET38622.1 - 4.2e-18 64.6 0.2 5.2e-18 64.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain MAT1 PF06391.8 AET38622.1 - 0.037 13.6 0.0 0.043 13.4 0.0 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 MCM PF00493.18 AET38623.1 - 3e-140 466.7 0.1 4e-140 466.3 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AET38623.1 - 7e-15 55.5 0.0 1.9e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 AET38623.1 - 1.6e-05 24.6 0.0 4.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AET38623.1 - 2.2e-05 23.7 0.0 0.004 16.3 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AET38623.1 - 0.0017 17.9 0.0 0.0061 16.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 AET38623.1 - 0.034 14.5 1.1 0.24 11.7 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AET38623.1 - 0.042 13.3 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IncA PF04156.9 AET38624.1 - 0.00046 19.8 4.3 0.00046 19.8 3.0 1.8 2 0 0 2 2 2 1 IncA protein CCDC155 PF14662.1 AET38624.1 - 0.0039 16.8 13.0 0.01 15.4 7.9 2.1 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 Jnk-SapK_ap_N PF09744.4 AET38624.1 - 0.0053 16.7 10.9 0.0094 15.9 7.6 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.3 AET38624.1 - 0.028 14.1 11.3 0.11 12.2 3.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 AET38624.1 - 0.033 13.9 12.4 4.1 7.1 8.4 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.8 AET38624.1 - 0.04 13.8 6.9 0.026 14.4 2.6 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF972 PF06156.8 AET38624.1 - 0.1 12.9 14.4 0.12 12.6 1.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 AET38624.1 - 0.17 11.7 14.6 0.46 10.3 2.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 AET38624.1 - 0.22 10.4 16.5 0.28 10.0 11.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GP20 PF06810.6 AET38624.1 - 0.22 10.9 19.1 0.065 12.6 6.6 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 AET38624.1 - 0.34 10.0 2.9 2.9 6.9 0.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Lebercilin PF15619.1 AET38624.1 - 0.35 10.2 16.0 0.99 8.7 11.1 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.3 AET38624.1 - 0.55 9.4 12.3 0.23 10.6 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF641 PF04859.7 AET38624.1 - 0.55 9.9 8.1 0.79 9.4 2.1 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.16 AET38624.1 - 0.57 10.1 11.5 0.81 9.6 1.0 3.5 2 1 1 3 3 3 0 bZIP transcription factor Tup_N PF08581.5 AET38624.1 - 0.62 10.3 8.0 0.14 12.3 1.6 2.5 1 1 1 2 2 2 0 Tup N-terminal V_ATPase_I PF01496.14 AET38624.1 - 0.7 7.6 7.3 0.94 7.2 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 AET38624.1 - 0.72 9.3 15.2 2.2 7.8 1.1 3.4 2 1 1 3 3 3 0 Septum formation initiator Cep57_CLD_2 PF14197.1 AET38624.1 - 0.93 9.4 10.0 4.4 7.3 0.4 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF724 PF05266.9 AET38624.1 - 0.93 9.0 10.2 5 6.6 7.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.7 AET38624.1 - 1.4 9.3 6.7 0.6 10.5 1.5 2.4 1 1 0 2 2 2 0 SlyX DUF4164 PF13747.1 AET38624.1 - 1.6 8.8 8.1 0.75 9.9 1.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ADIP PF11559.3 AET38624.1 - 1.7 8.5 18.6 1.7 8.4 7.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 AET38624.1 - 3.1 7.5 14.6 2.2 8.0 0.4 4.7 4 1 1 5 5 4 0 Homeobox associated leucine zipper Spc24 PF08286.6 AET38624.1 - 5.7 6.6 14.4 3 7.5 3.6 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 AET38624.1 - 7.4 6.5 7.5 8.7 6.3 0.4 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 AET38624.1 - 8.5 6.2 20.0 21 4.9 4.5 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0449 PF15136.1 AET38624.1 - 9.9 6.4 9.5 6.5 7.0 2.2 3.1 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 Cnd1 PF12717.2 AET38625.1 - 4.3e-52 176.5 13.2 8.4e-49 165.8 1.0 4.5 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 AET38625.1 - 3.8e-46 156.8 1.5 3.8e-46 156.8 1.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 AET38625.1 - 3.9e-12 46.2 0.0 0.00079 19.6 0.0 4.9 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 AET38625.1 - 1.5e-10 40.2 3.1 1.4 9.2 0.0 6.9 6 0 0 6 6 6 4 HEAT repeat Cnd3 PF12719.2 AET38625.1 - 7.4e-06 25.1 2.6 0.00012 21.1 0.3 3.1 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 AET38625.1 - 1e-05 25.8 1.9 0.18 12.3 0.0 5.5 5 0 0 5 5 5 1 HEAT-like repeat Ferrochelatase PF00762.14 AET38626.1 - 2e-87 293.1 0.0 2.3e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase MBOAT PF03062.14 AET38627.1 - 3.6e-60 203.7 15.9 6.7e-60 202.8 11.0 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Med4 PF10018.4 AET38628.1 - 8.2e-36 123.1 5.6 1.5e-35 122.3 3.9 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CorA PF01544.13 AET38628.1 - 0.085 11.8 3.7 0.12 11.3 2.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4187 PF13821.1 AET38629.1 - 1.7e-16 59.5 3.3 5.1e-16 58.0 2.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 AET38629.1 - 2.7e-05 23.8 1.0 4.8e-05 23.0 0.7 1.4 1 0 0 1 1 1 1 G-patch domain HutD PF05962.6 AET38629.1 - 0.064 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 HutD DUF3381 PF11861.3 AET38629.1 - 8.2 5.9 9.8 0.37 10.2 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) CAML PF14963.1 AET38629.1 - 8.4 5.6 9.9 0.62 9.3 3.2 1.7 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DcpS PF05652.7 AET38630.1 - 1.9e-41 140.8 1.1 3e-41 140.2 0.8 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 AET38630.1 - 5.2e-31 107.2 0.3 1.6e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 AET38630.1 - 0.083 13.4 0.2 0.33 11.5 0.1 2.0 2 0 0 2 2 2 0 HIT domain Longin PF13774.1 AET38631.1 - 2e-20 72.1 0.5 3.4e-20 71.3 0.4 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 AET38631.1 - 3.8e-15 55.2 0.0 6.7e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 AET38631.1 - 0.0016 18.2 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) NUDIX PF00293.23 AET38632.1 - 7.5e-17 61.2 0.1 9.8e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF410 PF04190.8 AET38633.1 - 1.4e-65 221.4 0.6 1.6e-65 221.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) SNAP PF14938.1 AET38633.1 - 0.0015 17.7 0.6 0.42 9.6 0.3 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP RHD3 PF05879.7 AET38634.1 - 4e-227 755.7 15.1 4.8e-227 755.4 10.5 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 AET38634.1 - 1.5e-05 24.8 0.4 5e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 AET38634.1 - 0.00017 22.0 1.2 0.00069 20.0 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 AET38634.1 - 0.00024 21.0 0.0 0.00086 19.2 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 AET38634.1 - 0.0017 17.3 0.0 0.0054 15.7 0.0 1.8 1 0 0 1 1 1 1 Septin DUF760 PF05542.6 AET38634.1 - 0.0082 16.2 0.9 1.3 9.2 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF760) AAA_29 PF13555.1 AET38634.1 - 0.058 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1793 PF08760.6 AET38634.1 - 0.07 12.9 1.0 0.46 10.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1793) AAA_28 PF13521.1 AET38634.1 - 0.077 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AET38634.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.4 2 1 1 3 3 3 0 AAA domain DinB PF05163.7 AET38635.1 - 0.013 15.1 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 DinB family XLF PF09302.6 AET38635.1 - 0.069 12.9 0.3 0.069 12.9 0.2 2.1 2 1 0 2 2 2 0 XLF (XRCC4-like factor) SRP9-21 PF05486.7 AET38635.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) PIN_4 PF13638.1 AET38636.1 - 7.5e-30 103.7 1.1 1.1e-29 103.2 0.1 1.8 2 0 0 2 2 2 1 PIN domain DUF4116 PF13475.1 AET38636.1 - 0.065 12.7 1.1 0.64 9.5 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Ribosomal_S28e PF01200.13 AET38637.1 - 7.4e-34 115.3 2.9 8e-34 115.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.7 AET38637.1 - 0.14 11.8 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Red1 PF07964.6 AET38638.1 - 5.2e-163 543.8 29.8 6.3e-163 543.6 20.6 1.1 1 0 0 1 1 1 1 Rec10 / Red1 tRNA-synt_1c PF00749.16 AET38639.1 - 3.7e-111 370.7 0.0 6.8e-111 369.8 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 AET38639.1 - 1.5e-52 177.4 0.9 2.3e-52 176.8 0.7 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 AET38639.1 - 8e-32 110.2 0.0 8e-31 107.0 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 AET38639.1 - 1.1e-23 83.6 0.8 3e-23 82.3 0.4 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 TMA7 PF09072.5 AET38640.1 - 7e-22 77.6 19.3 7.8e-22 77.5 13.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF2458 PF10454.4 AET38640.1 - 0.089 12.6 0.7 0.09 12.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) PolC_DP2 PF03833.8 AET38640.1 - 0.16 9.5 0.6 0.16 9.5 0.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF3987 PF13148.1 AET38640.1 - 0.17 10.3 0.6 0.19 10.2 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FinO_N PF12602.3 AET38640.1 - 1.4 9.2 5.0 2.1 8.7 3.5 1.3 1 0 0 1 1 1 0 Fertility inhibition protein N terminal Ras PF00071.17 AET38641.1 - 2.3e-55 186.3 0.3 2.7e-55 186.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET38641.1 - 2.9e-20 72.9 0.0 4.7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET38641.1 - 2.5e-16 59.4 0.2 3.3e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AET38641.1 - 1.5e-06 27.7 0.1 1e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AET38641.1 - 1.9e-06 27.2 0.2 2.3e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AET38641.1 - 5.3e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AET38641.1 - 2.4e-05 23.6 0.0 3.5e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 AET38641.1 - 0.00053 19.7 0.1 0.0013 18.4 0.0 1.5 1 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 AET38641.1 - 0.0074 16.4 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AET38641.1 - 0.012 14.8 0.0 0.04 13.1 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 AET38641.1 - 0.016 14.7 0.2 0.045 13.2 0.2 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 AET38641.1 - 0.02 15.2 0.8 0.026 14.8 0.5 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AET38641.1 - 0.026 14.5 0.0 0.04 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 AET38641.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AET38641.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DAGK_cat PF00781.19 AET38642.1 - 3.8e-25 87.8 0.0 6.3e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ATG22 PF11700.3 AET38643.1 - 6.3e-103 344.8 21.0 7.5e-103 344.5 14.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MgtE PF01769.11 AET38643.1 - 0.74 10.0 5.9 3.4 7.9 0.1 3.0 3 0 0 3 3 3 0 Divalent cation transporter Cpn60_TCP1 PF00118.19 AET38644.1 - 1.6e-116 389.8 9.9 1.8e-116 389.6 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1237 PF06824.6 AET38645.1 - 2.3e-171 570.0 0.0 2.8e-171 569.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DUF106 PF01956.11 AET38646.1 - 2.9e-52 176.5 1.4 3.5e-52 176.3 0.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 TatC PF00902.13 AET38646.1 - 0.41 10.0 4.7 4 6.7 0.9 2.1 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) ATP_bind_1 PF03029.12 AET38647.1 - 3.8e-84 281.9 0.1 5e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 AET38647.1 - 7.9e-08 31.9 0.0 2e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 AET38647.1 - 3.3e-07 29.9 0.4 4.8e-06 26.1 0.3 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AET38647.1 - 3.8e-05 23.8 0.0 0.00017 21.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 AET38647.1 - 0.00013 22.7 3.4 0.00024 21.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 AET38647.1 - 0.00014 21.3 0.0 0.0053 16.2 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 AET38647.1 - 0.00018 20.3 0.0 0.1 11.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 AET38647.1 - 0.00023 21.0 0.1 0.0041 17.0 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 AET38647.1 - 0.00047 20.0 0.0 0.0016 18.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain FeoB_N PF02421.13 AET38647.1 - 0.00097 18.4 0.1 0.024 13.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.7 AET38647.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 AET38647.1 - 0.0023 17.4 0.1 0.038 13.4 0.0 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 AET38647.1 - 0.0025 17.2 0.2 0.029 13.8 0.0 2.5 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.1 AET38647.1 - 0.0026 17.4 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 AET38647.1 - 0.0039 16.8 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 AET38647.1 - 0.0041 16.5 2.9 0.049 13.0 1.7 2.3 1 1 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 AET38647.1 - 0.0072 15.5 0.2 0.52 9.4 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 AET38647.1 - 0.0073 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 AET38647.1 - 0.013 14.7 0.0 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Miro PF08477.8 AET38647.1 - 0.014 15.8 0.1 0.59 10.6 0.1 2.5 1 1 0 1 1 1 0 Miro-like protein AAA_30 PF13604.1 AET38647.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 AET38647.1 - 0.033 13.3 0.0 0.45 9.6 0.0 2.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Glyco_tranf_2_3 PF13641.1 AET38647.1 - 0.033 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 FadA PF09403.5 AET38647.1 - 0.045 13.7 6.9 2.8 7.9 0.3 2.6 1 1 1 2 2 2 0 Adhesion protein FadA Arf PF00025.16 AET38647.1 - 0.054 12.7 0.0 4.1 6.6 0.0 2.5 2 1 0 2 2 2 0 ADP-ribosylation factor family Pox_D5 PF03288.11 AET38647.1 - 0.056 13.7 0.1 5.6 7.3 0.0 3.1 3 0 0 3 3 3 0 Poxvirus D5 protein-like NB-ARC PF00931.17 AET38647.1 - 0.065 12.0 0.0 0.15 10.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 AET38647.1 - 0.067 13.4 0.0 0.067 13.4 0.0 2.5 3 2 0 3 3 2 0 AAA domain DUF87 PF01935.12 AET38647.1 - 0.097 12.4 1.4 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 AET38647.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PAC2 PF09754.4 AET38648.1 - 3.6e-29 102.2 0.0 4.1e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 PAC2 family HEAT_2 PF13646.1 AET38649.1 - 5.4e-40 135.5 0.1 1.1e-17 64.0 0.0 3.3 2 1 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 AET38649.1 - 8.3e-17 59.9 0.3 0.0004 20.5 0.0 6.3 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.17 AET38649.1 - 1.6e-16 58.8 0.4 0.0037 17.2 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 AET38649.1 - 1.8e-12 47.3 2.1 6.3e-05 23.3 0.1 4.7 3 1 1 4 4 4 4 HEAT-like repeat Arm PF00514.18 AET38649.1 - 0.00013 21.6 0.7 3.7 7.5 0.0 4.3 2 2 2 4 4 4 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 AET38649.1 - 0.023 14.5 0.4 22 4.8 0.0 3.8 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 AET38649.1 - 0.05 13.5 1.2 3 7.8 0.2 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Ham1p_like PF01725.11 AET38650.1 - 2.6e-47 160.6 0.0 2.9e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family SEF14_adhesin PF06443.6 AET38650.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 SEF14-like adhesin Xpo1 PF08389.7 AET38651.1 - 4.8e-39 133.6 3.7 7.1e-39 133.0 0.4 2.8 2 0 0 2 2 2 1 Exportin 1-like protein ATP-gua_PtransN PF02807.10 AET38651.1 - 0.0029 17.7 0.1 0.097 12.8 0.0 3.0 3 0 0 3 3 3 1 ATP:guanido phosphotransferase, N-terminal domain AAA PF00004.24 AET38653.1 - 1.3e-16 60.9 0.0 7.3e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AET38653.1 - 1.6e-15 57.1 0.0 4.2e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 AET38653.1 - 6.5e-15 54.8 0.0 1.6e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 AET38653.1 - 9.8e-10 37.7 0.1 2.7e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 AET38653.1 - 1.6e-06 27.3 0.0 3.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AET38653.1 - 2.3e-06 27.8 0.0 1.4e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AET38653.1 - 1.8e-05 24.7 0.1 0.0025 17.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 AET38653.1 - 2.4e-05 24.0 0.0 3.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AET38653.1 - 9.1e-05 22.3 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AET38653.1 - 0.00018 21.1 0.0 0.00069 19.3 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 AET38653.1 - 0.0002 20.5 0.0 0.0045 16.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AET38653.1 - 0.00057 19.5 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 AET38653.1 - 0.0029 16.5 0.0 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 AET38653.1 - 0.0045 16.5 0.0 0.0094 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 AET38653.1 - 0.0064 16.0 0.0 0.023 14.2 0.0 1.9 2 0 0 2 2 1 1 DNA polymerase III, delta subunit DUF2075 PF09848.4 AET38653.1 - 0.0067 15.4 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DNA_pol3_gamma3 PF12169.3 AET38653.1 - 0.0084 15.8 0.0 0.043 13.5 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase III subunits gamma and tau domain III AAA_17 PF13207.1 AET38653.1 - 0.012 16.4 0.0 0.037 14.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.9 AET38653.1 - 0.014 15.1 0.2 0.11 12.1 0.1 2.6 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 AET38653.1 - 0.018 15.3 0.2 0.044 14.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain ResIII PF04851.10 AET38653.1 - 0.021 14.6 0.0 0.065 13.0 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 AET38653.1 - 0.024 14.3 0.1 0.32 10.6 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_3 PF07726.6 AET38653.1 - 0.037 13.6 0.0 0.29 10.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AET38653.1 - 0.049 13.0 0.0 0.57 9.5 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain SNF2_N PF00176.18 AET38653.1 - 0.052 12.3 0.0 1 8.0 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain TIP49 PF06068.8 AET38653.1 - 0.062 12.0 0.0 0.8 8.3 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus AAA_28 PF13521.1 AET38653.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AET38653.1 - 0.08 12.3 0.1 0.24 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AET38653.1 - 0.08 12.4 0.1 0.25 10.7 0.0 1.7 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 AET38653.1 - 0.098 12.9 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain Propeptide_C1 PF08127.8 AET38653.1 - 0.14 11.8 0.0 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Peptidase family C1 propeptide Yae1_N PF09811.4 AET38654.1 - 1.5e-11 43.6 0.2 1.9e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FAT PF02259.18 AET38655.1 - 6.4e-139 462.8 1.5 6.4e-139 462.8 1.0 2.2 3 0 0 3 3 3 1 FAT domain DUF3385 PF11865.3 AET38655.1 - 7.8e-65 217.6 0.8 7.8e-65 217.6 0.5 4.8 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 AET38655.1 - 3e-61 206.8 0.1 6.4e-61 205.8 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 AET38655.1 - 4.1e-43 145.5 4.4 8.6e-43 144.4 0.4 3.5 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 AET38655.1 - 3.7e-18 64.6 0.3 9.6e-18 63.3 0.2 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 AET38655.1 - 6.5e-15 55.1 5.6 0.33 11.2 0.0 9.0 6 2 3 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 AET38655.1 - 1.2e-10 41.5 0.3 0.00014 22.2 0.0 7.7 7 1 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 AET38655.1 - 1.1e-07 31.2 6.7 0.035 14.1 0.0 7.6 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.2 AET38655.1 - 0.018 15.4 9.6 3 8.2 0.0 6.4 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Actin PF00022.14 AET38656.1 - 1.6e-90 303.3 0.0 4.9e-90 301.7 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AET38656.1 - 0.00011 20.9 0.0 0.017 13.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Cpn60_TCP1 PF00118.19 AET38657.1 - 1.1e-141 472.7 3.9 1.3e-141 472.5 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 AET38657.1 - 0.032 14.0 0.1 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Resolvase, N terminal domain CPT PF07931.7 AET38657.1 - 0.076 12.6 1.8 7.2 6.2 0.1 2.7 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AP_endonuc_2 PF01261.19 AET38657.1 - 0.082 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TFIIS_C PF01096.13 AET38658.1 - 3.2e-18 65.0 6.9 5.5e-18 64.3 1.4 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AET38658.1 - 7e-10 38.4 10.6 2.6e-09 36.6 0.6 3.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 AET38658.1 - 0.0013 18.9 4.9 0.015 15.5 0.2 2.4 2 1 0 2 2 2 1 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 AET38658.1 - 0.0014 17.9 8.4 0.9 9.1 0.1 3.7 3 1 0 3 3 3 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AET38658.1 - 0.0063 16.2 3.1 0.044 13.6 0.3 2.4 2 1 0 2 2 2 1 Transposase zinc-ribbon domain DZR PF12773.2 AET38658.1 - 0.0091 15.7 8.2 0.28 11.0 0.1 3.1 2 1 0 2 2 2 1 Double zinc ribbon DUF2387 PF09526.5 AET38658.1 - 0.031 14.1 0.2 0.031 14.1 0.1 2.3 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-H2C2_2 PF13465.1 AET38658.1 - 0.044 14.0 4.7 0.39 11.0 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain RRN7 PF11781.3 AET38658.1 - 0.064 12.7 9.4 18 4.9 0.0 3.9 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 AET38658.1 - 0.086 12.1 12.5 0.34 10.2 2.1 3.1 2 2 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 AET38658.1 - 0.088 12.4 8.7 3.3 7.3 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 AET38658.1 - 0.094 12.0 4.7 0.21 10.9 0.8 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger C1_1 PF00130.17 AET38658.1 - 0.12 12.0 2.4 3.4 7.4 0.0 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_6 PF14835.1 AET38658.1 - 0.13 12.0 0.8 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Baculo_LEF5_C PF11792.3 AET38658.1 - 0.14 11.5 4.9 0.067 12.5 0.7 2.5 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Tmemb_9 PF05434.6 AET38658.1 - 0.16 11.7 0.7 0.26 11.0 0.1 1.6 2 0 0 2 2 2 0 TMEM9 Elf1 PF05129.8 AET38658.1 - 0.17 11.5 4.8 0.44 10.2 0.8 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C4_Topoisom PF01396.14 AET38658.1 - 0.27 10.7 7.6 0.2 11.1 0.8 3.0 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.1 AET38658.1 - 0.27 10.4 11.6 8.1 5.7 0.1 4.0 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 AET38658.1 - 0.43 10.5 10.8 14 5.7 0.8 3.4 3 1 0 3 3 3 0 Zinc ribbon domain zf-C3HC4_4 PF15227.1 AET38658.1 - 0.48 10.3 5.0 1.9 8.4 0.4 3.1 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING CpXC PF14353.1 AET38658.1 - 0.68 9.8 4.6 7.4 6.5 0.1 3.0 2 1 1 3 3 3 0 CpXC protein zinc_ribbon_4 PF13717.1 AET38658.1 - 0.7 9.6 11.5 3.7 7.3 0.1 3.5 4 0 0 4 4 3 0 zinc-ribbon domain zf-TFIIB PF13453.1 AET38658.1 - 0.8 8.9 5.3 0.17 11.1 0.7 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_Tnp_IS1 PF03811.8 AET38658.1 - 1.1 8.8 5.8 0.96 8.9 0.1 2.9 3 0 0 3 3 3 0 InsA N-terminal domain Stc1 PF12898.2 AET38658.1 - 1.5 8.9 6.2 4.1 7.5 0.2 2.2 1 1 1 2 2 2 0 Stc1 domain DUF2072 PF09845.4 AET38658.1 - 2.6 7.9 6.5 1.2 9.1 0.0 2.9 2 2 1 3 3 3 0 Zn-ribbon containing protein (DUF2072) zf-AN1 PF01428.11 AET38658.1 - 2.7 7.9 7.6 40 4.1 0.1 3.4 3 1 0 3 3 3 0 AN1-like Zinc finger Ogr_Delta PF04606.7 AET38658.1 - 3.6 7.3 8.7 1.4 8.5 3.2 2.4 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger zf-CHY PF05495.7 AET38658.1 - 3.9 7.7 7.3 13 6.0 0.1 2.9 2 1 0 2 2 2 0 CHY zinc finger PHD PF00628.24 AET38658.1 - 6.4 6.5 9.0 5.1 6.8 0.4 2.9 2 1 1 3 3 3 0 PHD-finger IBR PF01485.16 AET38658.1 - 7.8 6.4 10.3 8.8 6.2 1.7 3.0 2 2 0 2 2 2 0 IBR domain PRCC PF10253.4 AET38659.1 - 0.00051 20.7 3.6 0.00051 20.7 2.5 1.5 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting SSP160 PF06933.6 AET38659.1 - 0.34 8.8 4.5 0.42 8.5 3.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 AET38659.1 - 2.7 7.7 8.1 4.5 7.0 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LicD PF04991.8 AET38660.1 - 2e-48 165.2 1.6 2e-48 165.2 1.1 3.7 3 1 0 3 3 3 1 LicD family HSP70 PF00012.15 AET38660.1 - 4.9 4.9 22.7 7 4.4 15.7 1.2 1 0 0 1 1 1 0 Hsp70 protein CAF-1_p150 PF11600.3 AET38660.1 - 5.6 6.2 52.4 11 5.3 36.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal K_trans PF02705.11 AET38661.1 - 3e-176 586.9 23.9 3.6e-176 586.6 16.6 1.0 1 0 0 1 1 1 1 K+ potassium transporter HLH PF00010.21 AET38662.1 - 8.7e-12 44.5 3.1 1.9e-11 43.4 2.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UPF0175 PF03683.8 AET38662.1 - 0.0046 16.3 0.1 0.016 14.6 0.1 2.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) Ribosomal_60s PF00428.14 AET38662.1 - 0.005 17.2 7.6 0.005 17.2 5.3 4.4 3 2 2 5 5 5 1 60s Acidic ribosomal protein MRP-S31 PF15433.1 AET38662.1 - 0.0071 15.8 10.4 0.012 15.1 7.2 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 SDA1 PF05285.7 AET38662.1 - 8.3 5.5 25.9 7.3 5.7 17.3 1.3 1 1 0 1 1 1 0 SDA1 Pkinase PF00069.20 AET38663.1 - 5.6e-40 137.1 0.0 8.5e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38663.1 - 8.3e-11 41.4 0.0 1.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38663.1 - 0.0013 17.8 0.0 0.0031 16.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 AET38663.1 - 0.0041 16.2 0.0 0.0091 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family 7TM_GPCR_Srx PF10328.4 AET38663.1 - 0.13 11.3 0.6 0.19 10.7 0.4 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx AAA PF00004.24 AET38664.1 - 4.1e-57 192.0 0.0 4.8e-43 146.5 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 AET38664.1 - 2e-24 85.4 0.1 4.3e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 AET38664.1 - 1.9e-10 41.0 0.1 0.00038 20.5 0.0 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 AET38664.1 - 1.2e-08 35.2 0.2 0.018 15.1 0.0 3.9 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AET38664.1 - 2.3e-08 33.6 0.0 0.00028 20.3 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 AET38664.1 - 1.3e-07 31.2 0.6 1.9 7.8 0.0 4.3 2 2 2 4 4 4 3 AAA domain NACHT PF05729.7 AET38664.1 - 6.2e-06 25.9 0.1 0.15 11.7 0.0 3.6 3 0 0 3 3 3 2 NACHT domain AAA_14 PF13173.1 AET38664.1 - 1.3e-05 25.1 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 AET38664.1 - 8.5e-05 22.5 0.0 0.0013 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 AET38664.1 - 8.5e-05 23.3 0.0 0.098 13.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AET38664.1 - 8.7e-05 22.4 0.0 0.0074 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AET38664.1 - 0.0001 22.0 0.0 0.068 12.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 AET38664.1 - 0.00013 22.1 0.0 0.84 9.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 AET38664.1 - 0.00022 21.5 0.3 0.22 11.8 0.0 3.4 3 1 0 3 3 2 1 ABC transporter Arch_ATPase PF01637.13 AET38664.1 - 0.00022 21.0 0.3 0.88 9.2 0.0 3.9 3 1 1 4 4 4 1 Archaeal ATPase RuvB_N PF05496.7 AET38664.1 - 0.00045 19.3 0.0 0.0021 17.1 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 AET38664.1 - 0.0024 17.0 0.8 0.17 11.0 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 AET38664.1 - 0.0076 16.2 0.0 0.23 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 AET38664.1 - 0.014 14.3 0.0 1.9 7.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 AET38664.1 - 0.014 14.3 0.0 1.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 AET38664.1 - 0.016 14.6 0.0 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 AET38664.1 - 0.025 14.2 0.0 1.5 8.4 0.0 2.7 3 0 0 3 3 2 0 Bacterial dnaA protein Zeta_toxin PF06414.7 AET38664.1 - 0.025 13.6 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 AET38664.1 - 0.044 14.0 0.0 0.9 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AET38664.1 - 0.069 12.7 0.6 8 5.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.1 AET38664.1 - 0.094 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_19 PF13245.1 AET38664.1 - 0.11 12.2 0.1 5.8 6.7 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain M60-like PF13402.1 AET38664.1 - 0.18 10.6 0.2 0.3 9.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M60-like family Clat_adaptor_s PF01217.15 AET38665.1 - 5.2e-47 159.1 0.3 5.8e-47 158.9 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Thymidylate_kin PF02223.12 AET38666.1 - 3.3e-37 127.6 0.0 3.7e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 AET38666.1 - 0.0033 16.6 0.0 0.061 12.5 0.0 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 AET38666.1 - 0.1 12.4 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AET38666.1 - 0.14 12.3 0.0 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain SUR7 PF06687.7 AET38667.1 - 2e-38 132.0 12.0 2.4e-38 131.8 8.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 AET38667.1 - 0.092 12.6 13.5 0.26 11.1 9.4 1.7 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 zf-HIT PF04438.11 AET38668.1 - 2.6e-11 42.9 12.0 2.6e-11 42.9 8.3 2.0 2 0 0 2 2 2 1 HIT zinc finger Cyc-maltodext_C PF10438.4 AET38668.1 - 0.019 15.0 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Dak1 PF02733.12 AET38668.1 - 0.047 12.2 0.0 0.06 11.9 0.0 1.1 1 0 0 1 1 1 0 Dak1 domain YL1_C PF08265.6 AET38668.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-B_box PF00643.19 AET38668.1 - 0.3 11.0 14.4 1.7 8.5 6.6 2.5 2 0 0 2 2 2 0 B-box zinc finger zf-Mss51 PF13824.1 AET38668.1 - 0.63 9.9 8.4 3.5 7.5 5.8 2.3 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C3HC4_2 PF13923.1 AET38668.1 - 7.6 6.6 10.5 36 4.5 5.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Suc_Fer-like PF06999.7 AET38669.1 - 3.9e-33 115.3 0.0 7.2e-33 114.5 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like CPSF_A PF03178.10 AET38670.1 - 1.6e-56 191.7 1.4 1.6e-56 191.7 1.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region Gsf2 PF11055.3 AET38671.1 - 4e-165 548.8 0.4 4.6e-165 548.6 0.3 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 DUF2087 PF09860.4 AET38672.1 - 0.0059 16.3 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2087) TetR_C_3 PF08362.6 AET38672.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region DUF836 PF05768.9 AET38673.1 - 6.1e-17 61.6 0.4 7.6e-17 61.3 0.3 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 AET38673.1 - 0.035 14.0 0.1 0.061 13.3 0.1 1.6 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_2 PF13098.1 AET38673.1 - 0.058 13.5 0.4 0.075 13.2 0.3 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Laminin_N PF00055.12 AET38673.1 - 0.089 11.7 0.1 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Laminin N-terminal (Domain VI) DivIC PF04977.10 AET38674.1 - 0.011 15.2 4.1 0.011 15.2 2.9 8.2 4 3 4 8 8 8 0 Septum formation initiator AAA_13 PF13166.1 AET38674.1 - 1.7 7.0 86.6 0.019 13.4 13.2 3.6 1 1 1 3 3 3 0 AAA domain PAP2 PF01569.16 AET38675.1 - 8.8e-23 80.3 0.7 1.9e-22 79.3 0.5 1.5 1 0 0 1 1 1 1 PAP2 superfamily DsbB PF02600.11 AET38675.1 - 0.017 14.9 1.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB DUF4131 PF13567.1 AET38675.1 - 0.039 13.3 5.6 1.6 8.1 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 AET38675.1 - 0.17 10.5 7.5 0.042 12.5 1.1 2.1 2 0 0 2 2 2 0 Major Facilitator Superfamily Med20 PF08612.6 AET38676.1 - 6.2e-49 166.1 0.7 6.8e-49 166.0 0.5 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Vint PF14623.1 AET38676.1 - 0.0062 16.0 0.1 0.009 15.5 0.1 1.2 1 0 0 1 1 1 1 Hint-domain CTD_bind PF04818.8 AET38677.1 - 6.9e-22 77.4 0.7 1.9e-21 76.0 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. GCFC PF07842.7 AET38677.1 - 0.00023 20.6 0.2 0.00037 19.9 0.2 1.5 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein CTK3 PF12243.3 AET38677.1 - 0.012 15.2 0.3 0.043 13.4 0.1 1.9 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 ING PF12998.2 AET38677.1 - 0.035 14.3 4.7 0.057 13.6 0.0 3.0 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Ribosomal_L18ae PF01775.12 AET38677.1 - 0.073 12.9 0.1 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L18ae/LX protein domain AATF-Che1 PF13339.1 AET38677.1 - 2.3 8.3 9.9 5.5 7.1 4.2 2.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DEAD PF00270.24 AET38678.1 - 6.2e-23 81.1 0.0 2e-22 79.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 AET38678.1 - 5.6e-15 55.6 0.2 1.5e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 AET38678.1 - 2.3e-11 43.4 0.1 1.4e-10 40.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CDT1 PF08839.6 AET38678.1 - 0.0092 15.9 0.3 0.033 14.1 0.2 2.0 1 0 0 1 1 1 1 DNA replication factor CDT1 like SRX PF09201.5 AET38679.1 - 1.2e-49 167.7 3.6 2.5e-49 166.7 2.5 1.5 1 0 0 1 1 1 1 SRX SRP54 PF00448.17 AET38679.1 - 3.6e-47 160.3 0.1 7.3e-45 152.8 0.1 2.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 AET38679.1 - 2.2e-06 27.2 0.1 4.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 AET38679.1 - 0.00011 21.0 0.5 0.00048 18.9 0.0 2.3 3 1 0 3 3 3 1 ArgK protein SRP54_N PF02881.14 AET38679.1 - 0.0003 20.8 0.1 0.0011 18.9 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArsA_ATPase PF02374.10 AET38679.1 - 0.0024 16.9 0.6 0.094 11.7 0.1 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase MobB PF03205.9 AET38679.1 - 0.0042 16.7 0.0 0.013 15.1 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 AET38679.1 - 0.0095 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 AET38679.1 - 0.013 15.6 0.1 0.08 13.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 AET38679.1 - 0.02 14.8 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SURF2 PF05477.6 AET38679.1 - 0.035 13.2 3.9 0.066 12.3 2.7 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) AAA_14 PF13173.1 AET38679.1 - 0.058 13.2 0.0 0.42 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cyt-b5 PF00173.23 AET38680.1 - 5.5e-13 48.5 0.0 1.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 AET38680.1 - 5e-06 26.1 14.1 9.4e-06 25.2 9.8 1.5 1 1 0 1 1 1 1 Fatty acid desaturase V-ATPase_G PF03179.10 AET38681.1 - 7.1e-30 103.4 14.3 8e-30 103.2 9.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 AET38681.1 - 0.0088 15.2 18.9 0.076 12.2 13.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) DUF2362 PF10154.4 AET38681.1 - 0.02 13.6 6.5 0.021 13.5 4.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF16 PF01519.11 AET38681.1 - 0.032 14.4 5.5 0.042 14.0 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Meth_synt_2 PF01717.13 AET38681.1 - 0.043 12.7 1.4 0.056 12.4 1.0 1.0 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain ATP-synt_B PF00430.13 AET38681.1 - 0.18 11.6 18.6 0.56 10.0 12.9 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) FAM74 PF15026.1 AET38681.1 - 0.25 10.9 1.9 0.28 10.8 1.3 1.1 1 0 0 1 1 1 0 FAM74 protein DUF3810 PF12725.2 AET38681.1 - 0.25 10.1 3.3 0.31 9.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ASL_C2 PF14698.1 AET38681.1 - 0.39 10.8 2.7 0.92 9.6 0.3 2.1 1 1 1 2 2 2 0 Argininosuccinate lyase C-terminal GA PF01468.12 AET38681.1 - 0.74 10.0 7.4 0.22 11.6 1.6 2.4 2 1 0 2 2 2 0 GA module DUF87 PF01935.12 AET38681.1 - 0.81 9.4 3.8 0.97 9.1 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 DivIVA PF05103.8 AET38681.1 - 2.1 8.3 13.7 9.7 6.2 9.4 1.9 1 1 0 1 1 1 0 DivIVA protein Aldedh PF00171.17 AET38682.1 - 4.5e-125 417.5 0.0 5.3e-125 417.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SPC25 PF06703.6 AET38682.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) RRF PF01765.14 AET38683.1 - 1.6e-40 138.2 3.6 2.3e-40 137.7 2.5 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Apolipoprotein PF01442.13 AET38683.1 - 0.25 10.8 6.4 2 7.8 2.7 2.6 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain TPP_enzyme_N PF02776.13 AET38684.1 - 2e-35 121.8 0.0 2.8e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AET38684.1 - 2.5e-30 105.0 0.0 7.6e-30 103.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AET38684.1 - 2e-14 53.4 0.0 7e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HrpB4 PF09502.5 AET38684.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) RNB PF00773.14 AET38685.1 - 3.1e-51 174.6 0.0 3.1e-51 174.6 0.0 1.9 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.6 AET38685.1 - 0.0012 18.3 0.1 0.39 10.2 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease B OB domain Aldedh PF00171.17 AET38686.1 - 3.1e-97 325.8 0.0 3.7e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Brr6_like_C_C PF10104.4 AET38687.1 - 3.7e-44 149.4 0.1 5.2e-44 149.0 0.1 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain HDA2-3 PF11496.3 AET38688.1 - 2.8e-78 262.7 0.4 2.8e-78 262.7 0.3 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 TBPIP PF07106.8 AET38688.1 - 0.0064 16.0 25.4 0.085 12.4 7.1 2.6 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 AET38688.1 - 0.83 8.8 30.9 0.61 9.2 8.2 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 AET38688.1 - 2.2 8.2 5.0 2.4 8.0 1.5 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.6 AET38688.1 - 2.5 7.8 33.5 1.9 8.2 5.6 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Mhr1 PF12829.2 AET38689.1 - 1.1e-35 121.2 0.5 2.2e-35 120.3 0.3 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination TyeA PF09059.5 AET38689.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 TyeA FA_hydroxylase PF04116.8 AET38690.1 - 4.1e-13 49.7 12.5 4.1e-13 49.7 8.7 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily PepSY_TM_3 PF13706.1 AET38690.1 - 1.8 8.0 0.0 1.8 8.0 0.0 3.1 3 0 0 3 3 3 0 PepSY-associated TM helix OSCP PF00213.13 AET38691.1 - 7.5e-40 136.6 3.1 8.6e-40 136.4 2.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit TRAUB PF08164.7 AET38692.1 - 8.8e-28 96.2 3.9 1.1e-26 92.6 0.0 3.1 3 0 0 3 3 3 2 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 AET38692.1 - 9.3e-26 90.5 2.7 9.3e-26 90.5 1.9 2.4 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor MatE PF01554.13 AET38693.1 - 1e-51 174.7 28.4 4.7e-27 94.5 7.8 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 AET38693.1 - 2.3e-08 33.9 2.1 2.3e-08 33.9 1.5 4.7 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain PIH1 PF08190.7 AET38694.1 - 8.9e-26 91.0 1.3 1.1e-25 90.7 0.9 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 AA_kinase PF00696.23 AET38695.1 - 1e-34 120.1 0.1 1.8e-34 119.3 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 AET38695.1 - 2.2e-17 62.5 0.0 5.1e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 PUA domain CPSF_A PF03178.10 AET38696.1 - 3.8e-85 285.8 1.4 7.3e-85 284.8 0.3 2.0 2 0 0 2 2 2 1 CPSF A subunit region EPTP PF03736.12 AET38696.1 - 0.01 15.5 0.1 18 5.1 0.0 3.7 3 0 0 3 3 3 0 EPTP domain PIG-F PF06699.6 AET38697.1 - 4.2e-41 140.9 18.8 2.8e-40 138.3 13.0 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.14 AET38697.1 - 0.005 16.3 2.0 0.0062 16.0 1.4 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE AIM24 PF01987.12 AET38698.1 - 4.1e-09 36.2 0.0 5.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Zn_clus PF00172.13 AET38699.1 - 6e-08 32.4 7.1 1.4e-07 31.3 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 AET38700.1 - 9.2e-43 146.1 0.0 1.1e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DIM PF08194.7 AET38700.1 - 0.14 12.1 0.7 0.35 10.8 0.5 1.7 1 0 0 1 1 1 0 DIM protein Med6 PF04934.9 AET38701.1 - 1.4e-57 193.1 2.0 1.9e-57 192.7 1.4 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.5 AET38702.1 - 1.3e-25 89.0 0.5 2.1e-25 88.3 0.3 1.3 1 0 0 1 1 1 1 IGR protein motif HIT PF01230.18 AET38703.1 - 9.9e-27 93.3 0.2 1.9e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AET38703.1 - 4.2e-09 36.6 0.2 6.5e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF619 PF04768.8 AET38703.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF619) CwfJ_C_1 PF04677.10 AET38703.1 - 0.0055 16.3 0.1 0.0093 15.6 0.0 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Mob_Pre PF01076.14 AET38703.1 - 0.021 14.4 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Med28 PF11594.3 AET38703.1 - 0.041 14.1 0.0 0.078 13.2 0.0 1.4 1 1 0 1 1 1 0 Mediator complex subunit 28 COBRA1 PF06209.8 AET38705.1 - 0.0018 16.9 0.7 0.0027 16.3 0.5 1.2 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Med15 PF09606.5 AET38705.1 - 0.0035 15.6 21.2 0.0049 15.1 14.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 AET38705.1 - 0.013 15.7 1.3 0.013 15.7 0.9 2.2 2 1 0 2 2 2 0 AAA domain DUF2203 PF09969.4 AET38705.1 - 0.15 12.2 4.8 0.5 10.6 3.3 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF972 PF06156.8 AET38705.1 - 0.2 12.0 10.8 2.5 8.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pyr_redox_2 PF07992.9 AET38705.1 - 0.21 11.4 0.2 0.44 10.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4557 PF15101.1 AET38705.1 - 0.24 11.2 11.6 0.42 10.4 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) GH97_C PF14509.1 AET38705.1 - 0.27 11.3 2.5 0.84 9.7 1.7 1.8 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation PMT PF02366.13 AET38706.1 - 2.7e-19 69.5 20.0 2.7e-19 69.5 13.9 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AET38706.1 - 1.7e-08 34.2 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.6 AET38706.1 - 0.039 12.9 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF4131 PF13567.1 AET38706.1 - 5.9 6.2 11.5 0.19 11.0 2.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Med21 PF11221.3 AET38707.1 - 3e-44 150.4 5.1 3.5e-44 150.2 3.6 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TMCO5 PF14992.1 AET38707.1 - 0.0026 16.9 1.6 0.0029 16.7 1.1 1.3 1 0 0 1 1 1 1 TMCO5 family Med9 PF07544.8 AET38707.1 - 0.0096 15.6 2.3 0.019 14.6 0.1 2.4 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Katanin_con80 PF13925.1 AET38707.1 - 0.027 14.2 0.3 0.077 12.7 0.1 1.7 2 0 0 2 2 2 0 con80 domain of Katanin Spectrin PF00435.16 AET38707.1 - 0.048 13.9 4.7 0.46 10.7 0.4 2.1 2 0 0 2 2 2 0 Spectrin repeat RVT_N PF13655.1 AET38707.1 - 0.093 12.8 0.4 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase DUF4616 PF15394.1 AET38707.1 - 0.72 8.7 3.2 0.47 9.4 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4616) DUF4298 PF14131.1 AET38708.1 - 0.075 12.9 1.0 5.3 6.9 1.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) PBD PF00786.23 AET38709.1 - 0.062 13.7 0.4 0.24 11.8 0.3 2.1 1 0 0 1 1 1 0 P21-Rho-binding domain YfhO PF09586.5 AET38709.1 - 0.17 9.8 1.7 0.19 9.7 1.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RNase_P_p30 PF01876.11 AET38710.1 - 9.3e-48 161.2 0.1 1.3e-47 160.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Synaptobrevin PF00957.16 AET38711.1 - 0.03 13.9 0.1 0.29 10.7 0.0 2.6 2 0 0 2 2 2 0 Synaptobrevin Lectin_N PF03954.9 AET38711.1 - 0.15 11.4 3.4 0.26 10.6 0.1 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain HSP70 PF00012.15 AET38712.1 - 2.4e-77 260.2 3.2 1.5e-76 257.6 0.7 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 AET38712.1 - 1.5e-09 36.8 0.0 2.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Robl_LC7 PF03259.12 AET38712.1 - 0.0027 17.2 0.5 3.1 7.4 0.0 2.8 2 0 0 2 2 2 2 Roadblock/LC7 domain DUF2603 PF10788.4 AET38712.1 - 0.0066 16.2 0.2 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2603) BSD PF03909.12 AET38713.1 - 2.5e-25 87.9 6.9 8.9e-14 50.9 0.4 3.2 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 AET38713.1 - 6.2e-24 83.4 0.3 1.4e-23 82.2 0.2 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DEAD PF00270.24 AET38714.1 - 9.2e-48 161.9 0.0 2.1e-47 160.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET38714.1 - 1.3e-26 92.2 0.0 4.5e-26 90.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET38714.1 - 5.3e-06 26.3 0.0 3.5e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 AET38714.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_22 PF13401.1 AET38714.1 - 0.1 12.7 0.1 0.42 10.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain Brix PF04427.13 AET38715.1 - 5.7e-59 198.9 0.8 8.7e-59 198.4 0.6 1.3 1 0 0 1 1 1 1 Brix domain DUF2514 PF10721.4 AET38715.1 - 5.3e-05 22.9 2.7 7.7e-05 22.4 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) FYVE PF01363.16 AET38716.1 - 9.1e-18 63.9 11.9 9.1e-18 63.9 8.2 3.3 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 AET38716.1 - 3.3e-11 42.8 2.4 3.3e-11 42.8 1.7 3.9 3 2 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.1 AET38716.1 - 7.1e-05 22.4 1.1 7.1e-05 22.4 0.8 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 AET38716.1 - 0.00028 20.9 1.1 0.00028 20.9 0.8 3.7 3 1 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AET38716.1 - 0.00033 20.6 3.4 0.00033 20.6 2.4 4.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AET38716.1 - 0.00048 19.7 3.1 0.00048 19.7 2.2 5.1 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 AET38716.1 - 0.0098 15.8 2.9 0.0098 15.8 2.0 3.4 3 1 0 3 3 3 2 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 AET38716.1 - 0.02 14.7 1.9 0.02 14.7 1.3 4.5 4 1 1 5 5 5 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AET38716.1 - 1.1 9.0 29.9 0.14 11.9 2.1 4.5 5 0 0 5 5 5 0 zinc-RING finger domain MaoC_dehydrat_N PF13452.1 AET38717.1 - 0.00011 21.9 0.0 0.52 10.1 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MCR_D PF02505.9 AET38717.1 - 0.054 13.0 0.1 13 5.3 0.1 2.9 3 0 0 3 3 3 0 Methyl-coenzyme M reductase operon protein D MaoC_dehydratas PF01575.14 AET38717.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 MaoC like domain Ins_P5_2-kin PF06090.7 AET38718.1 - 8.7e-43 146.5 2.9 1.4e-42 145.8 2.0 1.3 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Response_reg PF00072.19 AET38718.1 - 0.014 15.4 0.1 0.1 12.6 0.0 2.0 1 1 1 2 2 2 0 Response regulator receiver domain DS PF01916.12 AET38719.1 - 2.7e-145 483.1 0.0 3.2e-145 482.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Methyltransf_23 PF13489.1 AET38720.1 - 6.5e-19 68.2 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AET38720.1 - 1.7e-10 41.2 0.1 1.3e-09 38.3 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 AET38720.1 - 4.9e-09 36.5 0.0 9e-07 29.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AET38720.1 - 6.4e-09 35.2 0.0 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 AET38720.1 - 1.3e-07 32.1 0.0 5.8e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET38720.1 - 2e-07 30.7 0.0 1.1e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET38720.1 - 7.4e-07 29.4 0.0 4.3e-06 27.0 0.0 2.4 3 1 0 3 3 3 1 Methyltransferase domain ECR1_N PF14382.1 AET38721.1 - 1.1e-11 43.8 0.2 3e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 AET38721.1 - 0.0077 16.1 0.0 2.6 8.0 0.0 3.1 3 0 0 3 3 3 2 Exosome component EXOSC1/CSL4 Met_10 PF02475.11 AET38722.1 - 4.9e-70 235.2 0.0 8.4e-70 234.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.10 AET38722.1 - 0.00026 20.5 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.11 AET38722.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Cyclin PF08613.6 AET38723.1 - 2.3e-11 44.3 0.4 4.4e-11 43.3 0.3 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AET38723.1 - 3.9e-09 36.1 0.5 3.9e-09 36.1 0.4 1.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain EAP30 PF04157.11 AET38725.1 - 1.7e-35 122.2 1.4 1.1e-34 119.5 1.0 2.0 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 AET38725.1 - 1.7e-32 111.0 0.7 3.7e-32 109.9 0.5 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 OrfB_Zn_ribbon PF07282.6 AET38725.1 - 0.0015 18.1 3.9 0.0058 16.2 0.1 2.6 1 1 2 3 3 3 1 Putative transposase DNA-binding domain GRAM PF02893.15 AET38725.1 - 0.0085 15.5 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 AET38725.1 - 0.017 14.6 0.1 0.017 14.6 0.1 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger bPH_3 PF14470.1 AET38725.1 - 0.027 14.7 0.1 0.077 13.2 0.1 1.8 1 0 0 1 1 1 0 Bacterial PH domain DZR PF12773.2 AET38725.1 - 0.029 14.1 6.6 0.13 12.0 4.8 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.13 AET38725.1 - 0.29 10.2 15.3 0.28 10.3 2.3 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others ABC_membrane_2 PF06472.10 AET38726.1 - 2e-60 204.3 4.7 2.4e-38 131.8 0.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AET38726.1 - 1.6e-17 64.1 0.0 3.6e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AET38726.1 - 1e-05 25.6 0.5 7.4e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain Lysis_S PF04971.7 AET38726.1 - 0.0016 18.1 0.4 0.24 11.0 0.0 2.5 2 0 0 2 2 2 1 Lysis protein S AAA_29 PF13555.1 AET38726.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 AET38726.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 AET38726.1 - 0.03 13.5 0.2 0.097 11.8 0.1 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AET38726.1 - 0.051 13.9 5.4 0.37 11.0 3.7 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AET38726.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 AET38726.1 - 0.11 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SUR7 PF06687.7 AET38727.1 - 1.2e-14 54.4 0.0 9.1e-14 51.5 0.0 2.0 1 1 0 1 1 1 1 SUR7/PalI family TarH PF02203.10 AET38727.1 - 0.091 12.5 0.1 0.091 12.5 0.1 3.8 5 0 0 5 5 5 0 Tar ligand binding domain homologue Fig1 PF12351.3 AET38727.1 - 0.69 9.7 13.0 0.045 13.6 2.9 2.8 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 Syndecan PF01034.15 AET38727.1 - 1.2 8.8 0.0 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Syndecan domain CTV_P6 PF06706.6 AET38727.1 - 1.6 8.2 4.0 29 4.2 0.1 2.7 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Mtr2 PF10429.4 AET38729.1 - 1.4e-71 239.6 0.3 1.6e-71 239.4 0.2 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 GATA PF00320.22 AET38730.1 - 2.9e-08 32.9 12.0 2.9e-08 32.9 8.3 2.2 2 0 0 2 2 2 1 GATA zinc finger Orn_Arg_deC_N PF02784.11 AET38731.1 - 9.1e-74 247.8 0.0 1.3e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 AET38731.1 - 2.7e-29 101.2 0.3 5.1e-29 100.3 0.2 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Voldacs PF03517.8 AET38732.1 - 3.7e-15 55.9 0.3 7.7e-15 54.9 0.2 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF1712 PF08217.6 AET38732.1 - 0.064 11.4 0.7 0.088 11.0 0.5 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Acyl_transf_1 PF00698.16 AET38733.1 - 1.5e-91 307.0 0.0 1.9e-90 303.4 0.0 2.9 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 AET38733.1 - 3.1e-36 123.4 0.0 6.4e-36 122.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 AET38733.1 - 1.6e-29 101.4 0.0 4.3e-29 100.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 AET38733.1 - 4.5e-12 45.8 0.0 1.5e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 AET38733.1 - 0.00067 18.8 0.0 0.0052 15.9 0.0 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase SRR1 PF07985.7 AET38734.1 - 7.7e-17 60.9 0.0 1.4e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 SRR1 Pribosyl_synth PF14572.1 AET38735.1 - 2.9e-42 144.4 1.7 2.6e-33 115.3 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 AET38735.1 - 3.6e-39 133.0 0.1 1.3e-38 131.3 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 AET38735.1 - 3.8e-08 33.1 0.3 9.1e-07 28.6 0.2 2.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AET38735.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Utp21 PF04192.7 AET38736.1 - 4.3e-78 261.6 0.0 6e-78 261.2 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 AET38736.1 - 1.9e-21 75.0 20.9 9.1e-09 34.8 0.8 9.1 9 1 0 9 9 9 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AET38736.1 - 4.3e-06 25.2 0.0 5.1e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain CPSF_A PF03178.10 AET38736.1 - 2.9e-05 23.3 0.2 0.01 14.9 0.0 3.1 3 1 1 4 4 4 2 CPSF A subunit region eIF2A PF08662.6 AET38736.1 - 0.00035 20.3 0.1 0.0079 15.9 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Utp12 PF04003.7 AET38736.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 AET38736.1 - 0.83 8.3 4.9 0.97 8.0 1.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Vps39_1 PF10366.4 AET38737.1 - 1e-33 115.5 3.8 1e-33 115.5 2.6 3.1 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 AET38737.1 - 2.4e-18 66.2 0.8 4.9e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 AET38737.1 - 1.1e-06 28.3 13.7 0.0057 16.2 2.7 3.3 2 1 0 2 2 2 2 Region in Clathrin and VPS DUF496 PF04363.7 AET38737.1 - 0.021 14.6 0.3 0.021 14.6 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF496) GCN5L1 PF06320.8 AET38738.1 - 1.7e-07 31.1 0.3 2e-07 30.8 0.2 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF4050 PF13259.1 AET38739.1 - 2.7e-22 78.9 0.4 4.8e-22 78.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Rxt3 PF08642.5 AET38740.1 - 1.4e-27 96.1 0.1 3.5e-27 94.9 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 Ribosomal_L31e PF01198.14 AET38741.1 - 3.9e-38 128.9 1.5 4.5e-38 128.7 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Dus PF01207.12 AET38742.1 - 1.8e-76 256.9 0.0 2.2e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 AET38742.1 - 0.072 12.0 0.0 0.28 10.1 0.0 1.8 1 1 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.16 AET38742.1 - 0.14 11.4 0.0 0.58 9.3 0.0 2.1 2 1 0 2 2 2 0 Histidine biosynthesis protein BRE1 PF08647.6 AET38743.1 - 1.1e-30 105.3 17.6 1.1e-30 105.3 12.2 5.1 4 1 1 5 5 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 AET38743.1 - 2.2e-06 27.6 12.4 4.4e-06 26.6 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AET38743.1 - 2.3e-06 27.1 11.0 4.4e-06 26.2 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AET38743.1 - 1e-05 25.0 12.6 2.2e-05 23.9 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET38743.1 - 4.9e-05 22.9 12.6 9.7e-05 22.0 8.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 AET38743.1 - 0.0029 17.3 10.6 0.0029 17.3 7.4 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C2H2 PF00096.21 AET38743.1 - 0.0047 17.1 0.1 0.0047 17.1 0.1 2.6 3 0 0 3 3 2 1 Zinc finger, C2H2 type Prok-RING_4 PF14447.1 AET38743.1 - 0.059 12.9 5.6 0.14 11.7 3.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 AET38743.1 - 0.06 13.0 6.8 0.23 11.1 4.7 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 AET38743.1 - 0.2 11.2 10.6 0.4 10.2 7.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 AET38743.1 - 1.5 8.6 7.9 0.4 10.4 3.1 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 AET38743.1 - 2.6 8.0 9.5 6.3 6.7 6.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1765 PF08578.5 AET38744.1 - 8.2e-24 84.0 6.2 8.2e-24 84.0 4.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Nucleoplasmin PF03066.10 AET38746.1 - 0.00074 19.0 1.6 0.0014 18.1 1.1 1.4 1 0 0 1 1 1 1 Nucleoplasmin zf-C2H2_4 PF13894.1 AET38746.1 - 0.005 17.0 3.1 0.048 13.9 0.3 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AET38746.1 - 0.027 14.7 23.0 0.084 13.2 0.8 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET38746.1 - 0.039 14.2 1.1 0.039 14.2 0.8 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AET38746.1 - 0.13 12.4 0.1 0.13 12.4 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding PBP1_TM PF14812.1 AET38746.1 - 0.33 11.2 12.8 0.045 14.0 5.8 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 AET38746.1 - 0.84 9.2 4.8 1.7 8.2 3.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3245 PF11595.3 AET38746.1 - 5 7.3 13.6 3.6 7.8 4.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Dus PF01207.12 AET38747.1 - 5.8e-44 150.1 0.0 5.4e-42 143.7 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 AET38747.1 - 0.00018 21.0 6.5 0.0021 17.7 0.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.7 AET38748.1 - 6.1e-49 166.0 0.3 6.8e-49 165.9 0.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DivIC PF04977.10 AET38748.1 - 3.4 7.2 5.0 3.7 7.1 2.1 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF3082 PF11282.3 AET38748.1 - 7.8 6.6 7.4 0.41 10.7 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3082) Bromodomain PF00439.20 AET38749.1 - 2.7e-40 136.1 0.1 1.2e-19 69.9 0.0 2.5 2 0 0 2 2 2 2 Bromodomain DSHCT PF08148.7 AET38750.1 - 3e-56 189.4 0.6 6.5e-56 188.4 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 AET38750.1 - 8.6e-23 80.6 0.0 1.9e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET38750.1 - 2.3e-07 30.5 0.0 7.2e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 AET38750.1 - 2.6e-05 23.5 0.1 5.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.10 AET38750.1 - 0.0021 17.8 0.1 0.01 15.6 0.1 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Ribonucleas_3_3 PF14622.1 AET38751.1 - 0.0012 18.8 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like AAA PF00004.24 AET38752.1 - 5.8e-88 291.8 0.0 6.9e-43 146.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AET38752.1 - 2.3e-13 49.7 0.0 1.9e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AET38752.1 - 2.2e-11 44.0 3.0 0.00011 22.3 0.1 5.2 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.1 AET38752.1 - 5.6e-11 42.7 0.2 6.5e-05 23.0 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 AET38752.1 - 2.7e-10 40.4 0.0 0.00028 20.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AET38752.1 - 4.7e-10 39.3 1.0 0.00078 19.1 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AET38752.1 - 2.3e-09 37.2 0.0 0.00023 21.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 AET38752.1 - 3.5e-07 29.2 0.0 0.017 13.8 0.0 2.6 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 AET38752.1 - 8.3e-07 28.9 0.0 0.00021 21.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain CDC48_N PF02359.13 AET38752.1 - 1.1e-06 28.5 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 AET38752.1 - 3e-06 28.0 0.0 0.089 13.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AET38752.1 - 6.7e-06 25.7 0.8 0.0048 16.6 0.1 3.4 3 0 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 AET38752.1 - 7.8e-06 25.4 6.2 0.62 9.4 0.0 4.4 2 2 1 4 4 4 2 AAA domain NACHT PF05729.7 AET38752.1 - 1.2e-05 25.0 0.4 0.08 12.6 0.0 4.0 4 0 0 4 4 4 1 NACHT domain Bac_DnaA PF00308.13 AET38752.1 - 1.2e-05 25.0 0.0 0.0034 17.0 0.0 2.6 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_28 PF13521.1 AET38752.1 - 1.7e-05 24.8 0.0 0.05 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 AET38752.1 - 2.2e-05 24.2 0.0 0.15 11.7 0.0 3.2 2 2 0 2 2 2 2 Archaeal ATPase Mg_chelatase PF01078.16 AET38752.1 - 2.4e-05 23.6 0.3 0.077 12.1 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AET38752.1 - 2.5e-05 24.3 0.0 0.17 12.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.8 AET38752.1 - 0.00012 20.9 0.0 0.17 10.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 AET38752.1 - 0.00036 20.8 0.1 0.19 12.0 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_3 PF07726.6 AET38752.1 - 0.00038 20.0 0.0 1.8 8.1 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 AET38752.1 - 0.00089 18.7 0.0 0.68 9.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 AET38752.1 - 0.00093 19.2 0.0 0.79 9.7 0.0 3.3 3 1 0 3 3 3 1 Sigma-54 interaction domain ABC_tran PF00005.22 AET38752.1 - 0.0011 19.2 0.0 0.055 13.7 0.0 2.8 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.7 AET38752.1 - 0.0018 17.4 0.0 0.81 8.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.1 AET38752.1 - 0.0029 17.2 0.0 0.85 9.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 AET38752.1 - 0.013 15.0 0.4 6.8 6.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 AET38752.1 - 0.014 14.9 0.0 0.099 12.1 0.0 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 AET38752.1 - 0.025 14.0 0.0 15 4.9 0.0 3.9 3 1 0 3 3 3 0 Sigma-54 interaction domain KaiC PF06745.8 AET38752.1 - 0.034 13.2 1.8 4.7 6.2 0.0 3.8 2 2 2 4 4 4 0 KaiC AFG1_ATPase PF03969.11 AET38752.1 - 0.047 12.4 0.0 0.31 9.8 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase NTPase_1 PF03266.10 AET38752.1 - 0.082 12.6 0.7 16 5.1 0.0 3.5 2 2 1 3 3 3 0 NTPase DUF815 PF05673.8 AET38752.1 - 0.093 11.6 0.0 3.8 6.3 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 AET38752.1 - 0.29 11.4 2.8 14 5.9 0.0 3.3 2 2 1 3 3 3 0 AAA domain Sec1 PF00995.18 AET38753.1 - 2.3e-66 224.6 4.7 5.3e-66 223.4 3.2 1.5 1 1 0 1 1 1 1 Sec1 family DUF3186 PF11382.3 AET38754.1 - 0.047 12.8 0.0 0.051 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) COX7C PF02935.11 AET38755.1 - 1.5e-21 75.9 1.3 1.6e-21 75.8 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Chromo_shadow PF01393.14 AET38755.1 - 0.046 13.5 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Chromo shadow domain zf-RING_5 PF14634.1 AET38756.1 - 1.6e-09 37.3 6.4 1.6e-09 37.3 4.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 AET38756.1 - 0.087 12.6 1.9 0.22 11.3 1.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IncA PF04156.9 AET38756.1 - 0.14 11.7 1.4 0.2 11.2 0.9 1.3 1 0 0 1 1 1 0 IncA protein Prok-RING_1 PF14446.1 AET38756.1 - 0.23 11.2 3.1 0.4 10.4 0.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 AET38756.1 - 0.33 10.9 7.5 0.53 10.3 2.9 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.1 AET38756.1 - 0.75 9.5 4.3 1.7 8.4 0.7 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AET38756.1 - 0.95 9.1 4.3 1.7 8.3 0.7 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Enkurin PF13864.1 AET38756.1 - 2.3 8.4 6.4 1.4 9.1 0.0 2.3 1 1 1 2 2 2 0 Calmodulin-binding zf-C3HC4 PF00097.20 AET38756.1 - 8.2 6.1 7.6 29 4.4 3.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AET38756.1 - 8.9 6.0 10.5 1.7 8.3 3.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 AET38756.1 - 9.2 5.9 8.0 18 4.9 2.8 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Aldo_ket_red PF00248.16 AET38757.1 - 1.8e-33 115.5 0.0 2.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Iso_dh PF00180.15 AET38758.1 - 1.6e-67 227.9 0.0 1.9e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF925 PF06042.6 AET38758.1 - 0.053 13.0 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF925) ATP-synt_10 PF05176.9 AET38759.1 - 3.3e-86 288.6 0.0 4.1e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Arrestin_N PF00339.24 AET38760.1 - 0.00061 19.6 0.1 0.0019 18.0 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CFEM PF05730.6 AET38761.1 - 8.8e-09 35.0 11.6 2e-08 33.8 8.1 1.7 1 0 0 1 1 1 1 CFEM domain Toxin_3 PF00537.13 AET38761.1 - 0.025 14.4 2.1 0.025 14.4 1.4 2.3 2 1 0 2 2 2 0 Scorpion toxin-like domain Tmemb_cc2 PF10267.4 AET38761.1 - 1.2 7.6 12.5 1.5 7.3 8.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pex19 PF04614.7 AET38762.1 - 1.7e-55 188.3 22.6 2.3e-55 187.9 15.6 1.1 1 0 0 1 1 1 1 Pex19 protein family PP2C_C PF07830.8 AET38762.1 - 0.5 10.5 3.0 1.3 9.1 0.1 3.1 3 1 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain XPC-binding PF09280.6 AET38762.1 - 1.1 8.7 4.5 0.37 10.2 0.2 2.4 3 0 0 3 3 3 0 XPC-binding domain SMAP PF15477.1 AET38762.1 - 1.7 8.9 6.9 16 5.8 1.0 3.4 1 1 1 2 2 2 0 Small acidic protein family Pox_A_type_inc PF04508.7 AET38762.1 - 4 7.4 9.9 35 4.5 0.0 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat UQ_con PF00179.21 AET38763.1 - 1.1e-44 151.2 0.3 1.2e-44 151.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AET38763.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AET38763.1 - 0.15 12.0 2.5 0.23 11.3 1.5 1.8 1 1 0 1 1 1 0 RWD domain FeoB_N PF02421.13 AET38764.1 - 0.38 10.0 4.7 0.39 9.9 2.1 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Beta-lactamase PF00144.19 AET38765.1 - 0.055 12.4 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase Peptidase_M16 PF00675.15 AET38766.1 - 6.1e-38 129.9 1.4 3.1e-37 127.6 0.1 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AET38766.1 - 2.4e-30 105.5 2.5 3.2e-17 62.8 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Ribosomal_S14 PF00253.16 AET38767.1 - 1.6e-19 69.0 3.4 1.8e-19 68.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 AET38767.1 - 0.07 12.8 0.3 0.083 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF2296 PF10058.4 AET38767.1 - 0.075 12.7 1.5 3.9 7.2 1.6 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Prim_Zn_Ribbon PF08273.7 AET38767.1 - 0.13 12.3 1.6 3.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF663 PF04950.7 AET38768.1 - 2.5e-96 322.1 0.0 3.5e-96 321.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AET38768.1 - 1.8e-21 75.4 0.0 3.3e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain zf-C2H2_2 PF12756.2 AET38769.1 - 3.5e-29 100.8 12.4 4.4e-29 100.5 0.2 2.9 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AET38769.1 - 0.059 13.5 1.1 0.059 13.5 0.8 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Vac14_Fig4_bd PF11916.3 AET38770.1 - 1.5e-71 239.3 4.7 4.1e-71 237.8 3.3 1.8 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 AET38770.1 - 8.3e-47 157.5 2.5 2.1e-39 133.7 0.1 4.2 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 AET38770.1 - 2.7e-14 51.9 1.4 0.00023 20.9 0.0 7.0 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 AET38770.1 - 3.3e-12 46.5 0.6 0.0028 17.8 0.0 6.0 4 2 1 5 5 5 2 HEAT repeats CLASP_N PF12348.3 AET38770.1 - 8.6e-09 35.0 2.2 0.00049 19.5 0.1 4.2 3 2 1 4 4 4 3 CLASP N terminal MMS19_C PF12460.3 AET38770.1 - 1.5e-05 23.9 17.3 0.12 11.0 0.8 4.9 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 AET38770.1 - 0.00018 21.9 2.4 0.077 13.5 0.0 5.0 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 AET38770.1 - 0.00038 20.3 9.6 1.9 8.3 0.1 4.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 AET38770.1 - 0.035 13.9 4.2 2.9 7.8 0.0 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Thioredoxin_4 PF13462.1 AET38770.1 - 0.1 12.5 3.0 0.095 12.7 0.4 2.1 2 0 0 2 2 2 0 Thioredoxin IKI3 PF04762.7 AET38772.1 - 0 1113.7 0.5 0 1112.2 0.0 1.7 2 0 0 2 2 2 1 IKI3 family Rad52_Rad22 PF04098.10 AET38773.1 - 2.7e-40 137.6 0.1 3.3e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RC-P840_PscD PF10657.4 AET38773.1 - 0.038 13.8 0.1 7 6.4 0.0 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction centre protein PscD NusG PF02357.14 AET38773.1 - 0.092 12.9 0.0 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 Transcription termination factor nusG DnaJ PF00226.26 AET38774.1 - 2.4e-25 88.0 3.6 4.2e-25 87.2 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AET38774.1 - 7.4e-21 73.8 0.4 1.6e-17 63.1 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AET38774.1 - 6.1e-14 51.8 18.2 1.3e-13 50.7 12.6 1.6 1 0 0 1 1 1 1 DnaJ central domain COP23 PF14218.1 AET38774.1 - 0.0056 16.2 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Circadian oscillating protein COP23 HypA PF01155.14 AET38774.1 - 0.0097 15.5 10.2 0.5 10.0 1.5 2.3 1 1 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Malate_DH PF12434.3 AET38774.1 - 0.034 13.8 0.8 0.034 13.8 0.6 2.1 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Methyltransf_26 PF13659.1 AET38775.1 - 1.6e-12 47.4 0.0 3.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET38775.1 - 1.8e-09 37.3 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AET38775.1 - 5.4e-09 35.6 0.0 8.4e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AET38775.1 - 2.5e-08 34.4 0.0 4.5e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET38775.1 - 6.2e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AET38775.1 - 0.00021 20.5 0.2 0.00031 19.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 AET38775.1 - 0.0034 16.7 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 AET38775.1 - 0.0043 17.5 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AET38775.1 - 0.0066 16.0 0.0 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.7 AET38775.1 - 0.008 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_12 PF08242.7 AET38775.1 - 0.01 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 AET38775.1 - 0.048 12.7 0.0 0.097 11.7 0.0 1.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 AET38775.1 - 0.049 12.7 0.0 0.089 11.9 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 AET38775.1 - 0.09 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Gcd10p PF04189.8 AET38776.1 - 5e-98 327.9 0.5 5e-98 327.9 0.4 1.4 2 0 0 2 2 2 1 Gcd10p family Nol1_Nop2_Fmu PF01189.12 AET38777.1 - 1.8e-107 358.9 0.1 3.6e-107 357.9 0.0 1.6 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 AET38777.1 - 0.00085 18.9 1.2 0.0016 18.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 AET38777.1 - 0.001 19.0 0.0 0.003 17.5 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase ATP-synt_G PF04718.10 AET38777.1 - 3.7 8.2 5.3 13 6.4 2.2 2.5 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit UPF0560 PF10577.4 AET38777.1 - 5.3 5.1 9.7 6.9 4.7 6.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Actin PF00022.14 AET38778.1 - 7.2e-46 156.3 0.0 2.3e-26 92.1 0.0 2.2 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 AET38778.1 - 0.0027 16.3 0.0 0.013 14.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Ras PF00071.17 AET38779.1 - 2.2e-56 189.7 0.0 2.6e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET38779.1 - 1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET38779.1 - 1.2e-08 34.3 0.0 2.1e-08 33.6 0.0 1.3 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 AET38779.1 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AET38779.1 - 0.0012 17.9 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AET38779.1 - 0.0013 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 AET38779.1 - 0.025 13.2 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 AET38779.1 - 0.035 13.7 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 AET38779.1 - 0.056 13.7 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Y_phosphatase2 PF03162.8 AET38782.1 - 3.7e-53 179.2 0.0 4.3e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AET38782.1 - 1.7e-06 28.3 0.0 2.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Arginase PF00491.16 AET38782.1 - 0.036 13.3 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Arginase family DSPc PF00782.15 AET38782.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Aminotran_1_2 PF00155.16 AET38783.1 - 2.8e-55 187.7 0.0 3.3e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 AET38783.1 - 0.0016 17.0 0.0 0.0022 16.5 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Porin_3 PF01459.17 AET38785.1 - 2.4e-60 204.1 0.2 2.7e-60 203.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Vac7 PF12751.2 AET38786.1 - 2.9e-18 65.9 16.1 2.6e-12 46.2 5.4 4.0 4 1 1 5 5 5 2 Vacuolar segregation subunit 7 PAT1 PF09770.4 AET38786.1 - 0.001 17.4 48.0 0.001 17.4 33.2 2.2 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 DSPc PF00782.15 AET38787.1 - 2e-36 124.5 0.5 2e-36 124.5 0.4 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AET38787.1 - 9.6e-05 21.8 3.3 0.00073 18.9 0.0 2.8 3 0 0 3 3 3 1 Protein-tyrosine phosphatase DSPn PF14671.1 AET38787.1 - 0.017 15.1 0.1 0.017 15.1 0.1 1.8 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half Init_tRNA_PT PF04179.7 AET38787.1 - 0.019 13.8 0.2 0.019 13.8 0.2 1.9 2 0 0 2 2 2 0 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 AET38787.1 - 0.1 12.6 0.4 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate COX4 PF02936.9 AET38788.1 - 1.6e-41 141.3 0.7 1.8e-41 141.2 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Methyltransf_16 PF10294.4 AET38789.1 - 0.0044 16.5 0.1 0.44 9.9 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase COG5 PF10392.4 AET38790.1 - 1.3e-38 131.9 2.8 1.3e-38 131.9 1.9 2.7 3 1 0 3 3 3 1 Golgi transport complex subunit 5 Med15_fungi PF05397.7 AET38790.1 - 4.5 7.2 11.3 0.1 12.5 1.8 2.5 3 0 0 3 3 3 0 Mediator complex subunit 15 DUF2011 PF09428.5 AET38791.1 - 1.4e-26 92.9 17.9 1.8e-26 92.5 12.4 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) DUF334 PF03904.8 AET38791.1 - 0.0065 15.8 3.4 0.0065 15.8 2.4 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF334) Sec23_trunk PF04811.10 AET38792.1 - 1.3e-70 237.5 0.1 2.8e-70 236.4 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AET38792.1 - 2.3e-24 84.8 0.0 6e-24 83.4 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 AET38792.1 - 2.8e-17 61.9 6.8 5.4e-17 61.0 4.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 AET38792.1 - 9.2e-17 61.3 1.5 1.4e-15 57.5 0.0 3.2 4 0 0 4 4 4 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 AET38792.1 - 1.3e-10 40.7 0.0 2.7e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Metallopep PF12044.3 AET38793.1 - 1.1e-165 551.2 0.0 1.8e-165 550.4 0.0 1.3 2 0 0 2 2 2 1 Putative peptidase family Jacalin PF01419.12 AET38793.1 - 8.2e-08 32.1 0.3 1.6e-06 27.9 0.1 2.7 2 1 0 2 2 2 1 Jacalin-like lectin domain Reprolysin_3 PF13582.1 AET38793.1 - 0.023 15.2 0.1 0.054 14.0 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 AET38793.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.19 AET38793.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Mob1_phocein PF03637.12 AET38794.1 - 4.1e-70 235.0 0.9 5e-70 234.7 0.6 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glycos_transf_1 PF00534.15 AET38795.1 - 6.4e-13 48.4 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AET38795.1 - 8.7e-05 22.6 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PH PF00169.24 AET38796.1 - 2.9e-15 56.3 0.8 7.1e-15 55.0 0.6 1.7 1 0 0 1 1 1 1 PH domain Ferritin PF00210.19 AET38796.1 - 0.1 12.3 0.2 0.73 9.5 0.2 2.3 2 0 0 2 2 2 0 Ferritin-like domain Syntaxin-6_N PF09177.6 AET38796.1 - 0.31 11.4 4.7 0.37 11.2 0.3 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Peptidase_M1 PF01433.15 AET38797.1 - 5.2e-54 183.8 0.0 6.9e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 AET38797.1 - 3.5e-25 88.2 0.1 7.9e-25 87.1 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 AET38797.1 - 2.9e-13 49.9 0.0 4.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily PRA1 PF03208.14 AET38798.1 - 2.1e-40 137.5 4.8 2.4e-40 137.3 3.3 1.0 1 0 0 1 1 1 1 PRA1 family protein FA_desaturase PF00487.19 AET38798.1 - 0.35 10.2 2.5 2.2 7.6 0.0 2.0 2 0 0 2 2 2 0 Fatty acid desaturase DUF2722 PF10846.3 AET38799.1 - 6e-73 246.2 11.9 1.8e-71 241.4 8.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) SHQ1 PF04925.10 AET38800.1 - 7.5e-74 247.2 1.6 1.2e-73 246.6 1.1 1.3 1 0 0 1 1 1 1 SHQ1 protein Diphthamide_syn PF01866.12 AET38801.1 - 1.6e-111 372.4 0.0 1.9e-111 372.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COG6 PF06419.6 AET38802.1 - 8.6e-153 509.7 20.5 8.6e-153 509.7 14.2 1.4 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Pro_CA PF00484.14 AET38804.1 - 4.9e-36 124.0 0.0 6.7e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Sedlin_N PF04628.8 AET38804.1 - 0.042 13.7 0.0 0.092 12.6 0.0 1.5 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region DUF4125 PF13526.1 AET38804.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) XhlA PF10779.4 AET38804.1 - 0.77 9.7 2.7 0.6 10.0 0.3 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Glyco_hydro_15 PF00723.16 AET38805.1 - 1.2e-50 172.4 0.0 1.7e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Complex1_LYR_2 PF13233.1 AET38806.1 - 4.3e-17 62.4 0.5 8.6e-17 61.5 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like DnaB_bind PF10410.4 AET38806.1 - 0.068 13.1 0.1 6.8 6.7 0.0 3.1 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase ALMT PF11744.3 AET38806.1 - 0.082 11.5 0.9 0.091 11.3 0.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1804 PF08822.6 AET38806.1 - 0.084 12.6 1.0 0.13 11.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Iso_dh PF00180.15 AET38807.1 - 2.7e-82 276.5 0.1 3e-82 276.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CLTH PF10607.4 AET38808.1 - 4.2e-28 97.8 1.9 4.2e-28 97.8 1.3 2.3 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.10 AET38808.1 - 0.018 14.9 0.0 0.053 13.4 0.0 1.8 1 0 0 1 1 1 0 U-box domain DUF489 PF04356.7 AET38808.1 - 0.12 11.9 2.0 0.24 10.9 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF2431 PF10354.4 AET38809.1 - 2.9e-56 190.0 0.1 4.1e-56 189.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PIG-H PF10181.4 AET38810.1 - 1.4e-23 82.3 0.8 2.3e-23 81.5 0.6 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-binding PF00249.26 AET38811.1 - 8e-09 35.4 0.0 1.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain WD40 PF00400.27 AET38812.1 - 3.5e-10 39.3 6.7 0.0004 20.1 0.7 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Pkinase PF00069.20 AET38813.1 - 2.3e-38 131.8 0.0 3.9e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38813.1 - 2e-29 102.4 0.0 2.8e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38813.1 - 0.00023 20.2 0.0 0.00038 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AET38813.1 - 0.052 13.2 0.0 0.2 11.3 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Hist_deacetyl PF00850.14 AET38814.1 - 1.3e-95 320.3 0.0 1.6e-95 319.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 AET38814.1 - 6.3e-48 162.5 0.0 9.2e-48 162.0 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Nol1_Nop2_Fmu PF01189.12 AET38815.1 - 8.1e-19 68.0 0.0 1.9e-18 66.8 0.0 1.5 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 AET38815.1 - 0.00013 21.9 0.0 0.00042 20.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Iso_dh PF00180.15 AET38816.1 - 5.3e-102 341.3 0.0 6.5e-102 341.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase R3H PF01424.17 AET38817.1 - 9.6e-13 47.6 0.0 1.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 AET38817.1 - 0.0006 19.7 156.5 0.0011 18.9 9.1 10.8 8 0 0 8 8 8 5 NF-X1 type zinc finger Methyltransf_16 PF10294.4 AET38818.1 - 1.3e-49 167.9 0.0 1.7e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 AET38818.1 - 0.0066 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AET38818.1 - 0.057 13.4 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AET38818.1 - 0.091 12.4 0.1 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MRP-S25 PF13741.1 AET38819.1 - 6e-89 297.4 0.5 6.9e-89 297.2 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 AET38819.1 - 3e-06 27.1 0.2 0.0022 17.8 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial ribosomal protein S23 DUF1242 PF06842.7 AET38820.1 - 9.3e-16 57.0 1.5 1.2e-15 56.6 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF1253 PF06862.7 AET38821.1 - 2.2e-159 530.6 11.6 2.9e-159 530.1 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 AET38821.1 - 0.0022 17.5 2.0 0.033 13.7 0.6 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase ICE2 PF08426.5 AET38822.1 - 9.5e-161 535.0 34.7 1.1e-160 534.7 24.1 1.0 1 0 0 1 1 1 1 ICE2 Cyclin_N PF00134.18 AET38823.1 - 1.3e-17 63.5 0.5 8.3e-17 60.9 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AET38823.1 - 0.00048 20.0 1.2 0.064 13.1 0.1 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain TRAM_LAG1_CLN8 PF03798.11 AET38824.1 - 3e-40 137.8 27.4 3e-40 137.8 19.0 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 AET38824.1 - 8.7e-17 60.3 1.1 8.7e-17 60.3 0.8 2.6 2 0 0 2 2 2 1 TRAM1-like protein Aa_trans PF01490.13 AET38825.1 - 6.7e-95 317.9 18.8 7.8e-95 317.7 13.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PepSY_TM_2 PF13703.1 AET38825.1 - 0.00039 20.5 2.0 0.00039 20.5 1.4 3.6 5 0 0 5 5 5 1 PepSY-associated TM helix Y_phosphatase2 PF03162.8 AET38826.1 - 4.2e-63 211.6 0.5 5.4e-63 211.2 0.0 1.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AET38826.1 - 7.9e-07 29.4 0.0 1.7e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 AET38826.1 - 0.0019 17.7 0.0 0.0041 16.6 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AET38826.1 - 0.0024 17.2 0.7 0.0046 16.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF2416 PF10315.4 AET38827.1 - 5.1e-37 126.4 1.1 6e-37 126.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) Histone PF00125.19 AET38828.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AET38828.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AET38828.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AET38828.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 AET38829.1 - 2.5e-14 53.1 0.1 3e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 AET38829.1 - 5.4e-05 23.0 0.2 7.9e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 AET38829.1 - 6.1e-05 23.1 0.1 8.8e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AET38829.1 - 9.4e-05 22.4 0.1 0.00017 21.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 AET38829.1 - 0.0018 17.5 0.0 0.0019 17.5 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 AET38829.1 - 0.0041 16.8 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 AET38829.1 - 0.033 14.4 0.2 0.057 13.7 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 AET38829.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-H2C2_2 PF13465.1 AET38830.1 - 7.3e-13 48.1 8.9 5.5e-07 29.5 0.2 3.9 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 AET38830.1 - 9.4e-13 47.6 13.7 2.6e-06 27.4 1.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET38830.1 - 1.4e-11 43.9 9.9 0.00015 21.8 1.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 AET38830.1 - 2.5e-06 27.4 4.8 1.8e-05 24.7 0.5 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AET38830.1 - 2.9e-05 24.0 8.4 0.0011 19.0 0.5 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.1 AET38830.1 - 0.0057 16.8 2.7 0.0057 16.8 1.9 2.2 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Ino80_Iec3 PF14612.1 AET38830.1 - 0.031 14.3 0.3 0.031 14.3 0.2 2.1 2 1 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling FYVE PF01363.16 AET38830.1 - 0.1 12.5 4.9 0.23 11.3 3.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-H2C2_5 PF13909.1 AET38830.1 - 0.2 11.9 0.9 2.3 8.6 1.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 AET38830.1 - 0.78 9.5 8.0 2 8.2 0.8 3.1 2 1 1 3 3 3 0 BED zinc finger C1_4 PF07975.7 AET38830.1 - 0.81 9.7 3.5 7.5 6.6 2.5 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.1 AET38830.1 - 2.9 7.9 5.8 11 6.1 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Bac_surface_Ag PF01103.18 AET38831.1 - 9.6e-47 159.9 6.6 1.3e-46 159.5 4.5 1.2 1 0 0 1 1 1 1 Surface antigen DFP PF04127.10 AET38832.1 - 7.2e-16 58.3 0.0 1.5e-06 28.0 0.0 3.1 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RRM_1 PF00076.17 AET38833.1 - 2e-50 168.3 0.6 2.8e-18 65.3 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET38833.1 - 1.4e-27 95.4 0.1 2.1e-10 40.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET38833.1 - 2.1e-25 88.3 0.7 2.3e-09 36.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AET38833.1 - 0.067 12.9 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Frataxin_Cyay PF01491.11 AET38835.1 - 2e-32 111.1 0.0 3.2e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Frataxin-like domain CPSase_sm_chain PF00988.17 AET38835.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain Inhibitor_I9 PF05922.11 AET38836.1 - 0.0057 17.2 0.3 0.059 13.9 0.2 2.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 Glyco_hydro_38 PF01074.17 AET38837.1 - 1.8e-78 263.5 1.4 2.9e-77 259.6 0.4 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 AET38837.1 - 2.9e-65 220.8 1.4 4.3e-65 220.3 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 AET38837.1 - 1.1e-21 76.7 0.0 2.6e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Prenyltrans PF00432.16 AET38838.1 - 7.3e-32 108.6 0.2 1e-06 28.1 0.0 4.7 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AET38838.1 - 1.1e-14 54.7 0.0 0.00011 22.5 0.0 3.2 2 1 1 3 3 3 3 Prenyltransferase-like MsyB PF13984.1 AET38838.1 - 0.042 13.9 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 MsyB protein DUF2393 PF09624.5 AET38838.1 - 0.077 12.5 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Mito_carr PF00153.22 AET38839.1 - 2.2e-53 177.9 5.0 2.1e-21 75.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ACPS PF01648.15 AET38840.1 - 9.2e-12 44.7 0.0 1.5e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Pex14_N PF04695.8 AET38841.1 - 7.9e-33 113.3 0.5 7.9e-33 113.3 0.3 2.8 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Myosin_tail_1 PF01576.14 AET38841.1 - 0.0019 16.0 10.4 0.0031 15.3 7.2 1.4 1 0 0 1 1 1 1 Myosin tail CR6_interact PF10147.4 AET38841.1 - 0.0035 16.6 1.3 0.0035 16.6 0.9 1.7 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TMF_DNA_bd PF12329.3 AET38841.1 - 0.019 14.7 4.7 0.019 14.7 3.3 3.6 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 AET38841.1 - 0.029 14.1 7.6 0.055 13.2 4.6 2.0 2 0 0 2 2 1 0 Laminin Domain II Spc7 PF08317.6 AET38841.1 - 0.044 12.4 10.7 0.095 11.3 7.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein NCA2 PF08637.5 AET38841.1 - 0.054 12.3 2.0 2.1 7.1 0.3 2.2 1 1 1 2 2 2 0 ATP synthase regulation protein NCA2 MbeD_MobD PF04899.7 AET38841.1 - 0.063 13.1 1.3 0.2 11.5 0.9 1.9 1 0 0 1 1 1 0 MbeD/MobD like SF-assemblin PF06705.6 AET38841.1 - 0.064 12.3 8.8 0.12 11.4 6.1 1.4 1 0 0 1 1 1 0 SF-assemblin/beta giardin HeLo PF14479.1 AET38841.1 - 0.074 12.7 4.7 0.048 13.4 2.0 1.6 2 0 0 2 2 1 0 Prion-inhibition and propagation V_ATPase_I PF01496.14 AET38841.1 - 0.082 10.7 4.5 0.11 10.3 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 AET38841.1 - 0.085 12.0 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Uds1 PF15456.1 AET38841.1 - 0.096 12.6 7.7 2 8.4 1.2 2.9 1 1 1 2 2 2 0 Up-regulated During Septation Syntaxin PF00804.20 AET38841.1 - 0.11 12.6 9.3 5.8 7.1 6.4 2.6 1 1 0 1 1 1 0 Syntaxin DUF2604 PF10790.4 AET38841.1 - 0.12 12.5 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF2604) ECH_C PF13766.1 AET38841.1 - 0.12 12.4 1.9 0.47 10.6 0.4 2.6 3 0 0 3 3 2 0 2-enoyl-CoA Hydratase C-terminal region YhdB PF14148.1 AET38841.1 - 0.13 12.0 1.0 0.5 10.1 0.0 2.4 3 0 0 3 3 3 0 YhdB-like protein IncA PF04156.9 AET38841.1 - 0.14 11.6 14.8 0.12 11.9 9.4 1.6 1 1 0 1 1 1 0 IncA protein IFT57 PF10498.4 AET38841.1 - 0.22 10.2 11.0 0.36 9.5 7.6 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Mnd1 PF03962.10 AET38841.1 - 0.22 11.1 13.1 3.8 7.1 8.7 2.4 1 1 1 2 2 2 0 Mnd1 family DUF3736 PF12540.3 AET38841.1 - 0.24 11.6 3.6 0.39 10.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3736) APG6 PF04111.7 AET38841.1 - 0.4 9.6 12.1 0.79 8.7 8.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 CCDC-167 PF15188.1 AET38841.1 - 0.45 10.5 7.7 0.12 12.2 1.2 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 LXG PF04740.7 AET38841.1 - 0.74 9.5 11.1 0.35 10.6 4.5 2.3 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF1664 PF07889.7 AET38841.1 - 0.9 9.3 8.1 3.2 7.5 3.8 2.7 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 AET38841.1 - 1.7 6.9 10.6 4 5.7 7.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF4298 PF14131.1 AET38841.1 - 2 8.3 5.6 4.7 7.1 1.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4298) DUF1043 PF06295.7 AET38841.1 - 4.5 6.9 15.9 0.15 11.6 1.8 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1043) FlaC_arch PF05377.6 AET38841.1 - 6.3 6.7 7.7 21 5.1 0.1 3.3 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) Med5 PF08689.5 AET38842.1 - 4.7e-247 822.3 36.9 5.3e-247 822.1 25.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SNF2_N PF00176.18 AET38843.1 - 1.8e-70 237.1 1.0 1.8e-70 237.1 0.7 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 AET38843.1 - 7.1e-53 178.4 23.2 7.1e-53 178.4 16.1 5.4 6 0 0 6 6 6 1 DNA-binding domain Helicase_C PF00271.26 AET38843.1 - 1.3e-13 50.6 0.0 4.3e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PKK PF12474.3 AET38844.1 - 0.0065 16.2 6.2 0.0086 15.8 4.3 1.2 1 0 0 1 1 1 1 Polo kinase kinase XRCC4 PF06632.7 AET38844.1 - 0.027 13.3 0.6 0.03 13.1 0.4 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 FUSC PF04632.7 AET38844.1 - 0.029 12.8 0.7 0.032 12.6 0.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.10 AET38844.1 - 0.031 13.4 0.3 0.035 13.3 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit VPR PF00522.13 AET38844.1 - 0.05 13.4 0.1 0.081 12.7 0.1 1.4 1 0 0 1 1 1 0 VPR/VPX protein IncA PF04156.9 AET38844.1 - 0.054 13.0 6.8 0.08 12.5 4.7 1.2 1 0 0 1 1 1 0 IncA protein Hpt PF01627.18 AET38844.1 - 0.1 12.5 0.7 4.2 7.4 0.0 2.4 2 1 0 2 2 2 0 Hpt domain APG6 PF04111.7 AET38844.1 - 0.14 11.2 3.3 0.17 10.9 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 LXG PF04740.7 AET38844.1 - 0.31 10.7 4.6 0.3 10.8 1.6 1.8 1 1 1 2 2 2 0 LXG domain of WXG superfamily Ferritin PF00210.19 AET38844.1 - 0.34 10.6 3.2 1.8 8.3 2.2 1.8 1 1 1 2 2 2 0 Ferritin-like domain DUF1664 PF07889.7 AET38844.1 - 0.43 10.3 3.5 0.63 9.8 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 AET38844.1 - 0.5 9.8 5.4 1.2 8.6 3.7 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CorA PF01544.13 AET38844.1 - 0.82 8.6 4.0 1 8.3 2.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GrpE PF01025.14 AET38844.1 - 0.88 9.0 6.1 4.6 6.7 0.1 2.1 1 1 1 2 2 2 0 GrpE KfrA_N PF11740.3 AET38844.1 - 1.1 9.6 4.5 0.3 11.5 0.3 1.9 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4140 PF13600.1 AET38844.1 - 8.9 6.8 6.8 5.2 7.5 0.7 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) EMP24_GP25L PF01105.19 AET38845.1 - 2.2e-05 24.2 0.1 0.011 15.4 0.0 2.2 2 0 0 2 2 2 2 emp24/gp25L/p24 family/GOLD RNase_PH PF01138.16 AET38846.1 - 3.3e-13 50.1 0.1 5.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AET38846.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SpoU_methylase PF00588.14 AET38847.1 - 1.6e-26 92.8 0.1 4.6e-26 91.4 0.0 1.9 2 0 0 2 2 2 1 SpoU rRNA Methylase family adh_short PF00106.20 AET38848.1 - 4.8e-27 94.9 0.0 8.1e-27 94.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AET38848.1 - 9.6e-10 38.4 0.0 1.1e-08 34.9 0.0 2.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AET38848.1 - 0.00015 21.6 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 AET38848.1 - 0.0032 16.4 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 AET38848.1 - 0.0049 16.3 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1762 PF08574.5 AET38849.1 - 1.7e-19 70.0 10.4 1.7e-19 70.0 7.2 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF1762) Ribosomal_L6 PF00347.18 AET38850.1 - 2.3e-31 108.0 10.0 1.4e-17 63.9 2.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.11 AET38850.1 - 0.032 13.4 1.3 0.14 11.4 0.0 2.4 3 0 0 3 3 3 0 Transcriptional Coactivator p15 (PC4) YbbR PF07949.7 AET38850.1 - 0.081 13.0 3.2 0.47 10.6 0.2 3.1 1 1 2 3 3 3 0 YbbR-like protein LRR_4 PF12799.2 AET38850.1 - 0.19 11.3 0.8 14 5.4 0.0 2.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) WSC PF01822.14 AET38851.1 - 3.7e-12 46.0 7.5 4.5e-12 45.7 5.2 1.1 1 0 0 1 1 1 1 WSC domain SUR7 PF06687.7 AET38851.1 - 0.016 14.8 1.2 0.018 14.6 0.8 1.2 1 0 0 1 1 1 0 SUR7/PalI family Nup84_Nup100 PF04121.8 AET38852.1 - 6.7e-219 728.0 10.7 7.9e-219 727.8 7.4 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DASH_Dad3 PF08656.5 AET38852.1 - 0.026 14.1 0.3 0.16 11.6 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 SH3_1 PF00018.23 AET38853.1 - 2.7e-08 33.0 0.0 7.9e-08 31.5 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AET38853.1 - 0.0058 16.1 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.14 AET38853.1 - 0.052 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Chorismate_synt PF01264.16 AET38854.1 - 1.8e-134 447.5 0.0 2.1e-134 447.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase RINT1_TIP1 PF04437.8 AET38855.1 - 1.6e-86 290.8 26.2 1.6e-86 290.8 18.2 2.1 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CCDC142 PF14923.1 AET38855.1 - 0.00074 17.9 0.4 0.0044 15.4 0.0 2.2 2 0 0 2 2 2 1 Coiled-coil protein 142 DUF948 PF06103.6 AET38855.1 - 0.34 10.8 6.5 0.39 10.6 0.2 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF676 PF05057.9 AET38856.1 - 5.2e-57 192.6 0.0 8.3e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 AET38856.1 - 0.00014 21.4 0.0 0.00038 20.0 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AET38856.1 - 0.0032 17.2 0.0 0.007 16.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AET38856.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein RF-1 PF00472.15 AET38857.1 - 2.4e-39 133.6 3.3 5.6e-39 132.4 2.3 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 AET38857.1 - 5.6e-30 103.4 0.0 2e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 PCRF domain CheR_N PF03705.10 AET38857.1 - 0.01 15.1 0.1 0.027 13.8 0.0 1.7 1 1 0 1 1 1 0 CheR methyltransferase, all-alpha domain Pkinase PF00069.20 AET38858.1 - 1.2e-70 237.6 0.0 1.3e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38858.1 - 3.4e-30 104.9 0.0 4.4e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38858.1 - 0.00015 20.8 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AET38858.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 AET38858.1 - 0.016 14.5 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 RIO1 family DAO PF01266.19 AET38859.1 - 5.7e-48 163.6 0.0 6.4e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AET38859.1 - 2.1e-07 30.8 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AET38859.1 - 0.0052 16.8 0.0 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AET38859.1 - 0.0054 17.0 0.1 0.013 15.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AET38859.1 - 0.055 13.2 0.1 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 AET38859.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 AET38859.1 - 0.097 12.5 0.0 0.63 9.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AET38859.1 - 0.15 10.9 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 AET38859.1 - 0.15 10.8 0.3 0.27 10.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain TPR_11 PF13414.1 AET38860.1 - 0.00019 21.0 1.7 0.052 13.1 0.2 3.5 2 2 1 3 3 3 2 TPR repeat Dockerin_1 PF00404.13 AET38860.1 - 0.021 14.4 0.1 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Dockerin type I repeat Sel1 PF08238.7 AET38860.1 - 0.04 14.5 0.9 77 4.1 0.0 4.2 5 0 0 5 5 5 0 Sel1 repeat TPR_8 PF13181.1 AET38860.1 - 0.054 13.2 6.8 2.4 8.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.12 AET38861.1 - 1.9e-95 320.3 43.3 2.5e-95 319.9 30.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HECT PF00632.20 AET38862.1 - 3.1e-82 276.2 0.7 5.6e-82 275.4 0.5 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 AET38862.1 - 0.097 12.3 0.2 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif SPRY PF00622.23 AET38863.1 - 2.5e-14 53.4 0.1 4.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF1158 PF06643.6 AET38863.1 - 0.32 11.3 3.1 0.63 10.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) WBP-1 PF11669.3 AET38864.1 - 0.026 14.5 5.0 0.028 14.4 3.5 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 PAP2_C PF14360.1 AET38864.1 - 4.2 7.7 6.1 6 7.2 3.6 1.9 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Homeobox PF00046.24 AET38865.1 - 9.2e-20 70.0 2.8 1.7e-19 69.2 1.9 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AET38865.1 - 0.00055 19.5 1.3 0.0019 17.8 0.9 2.0 1 0 0 1 1 1 1 Homeobox KN domain Aldedh PF00171.17 AET38868.1 - 5.6e-162 539.2 0.0 6.3e-162 539.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AET38868.1 - 0.0014 17.4 0.1 0.0074 15.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 AET38868.1 - 0.014 14.6 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Zn_clus PF00172.13 AET38869.1 - 8.5e-08 31.9 10.1 1.5e-07 31.1 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_mis_repair PF01119.14 AET38870.1 - 2.9e-31 107.4 0.9 5.3e-31 106.5 0.1 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 AET38870.1 - 2.1e-14 53.3 0.2 5.7e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AET38870.1 - 2.6e-09 36.7 1.2 6.5e-09 35.5 0.1 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GM_CSF PF01109.12 AET38870.1 - 0.056 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Ank PF00023.25 AET38871.1 - 1.3e-15 56.3 0.1 1.5e-07 30.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 AET38871.1 - 2.4e-12 46.9 0.1 7.1e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 AET38871.1 - 2.8e-12 46.4 1.0 2.4e-10 40.2 0.1 2.8 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.1 AET38871.1 - 8.7e-10 37.8 0.1 0.00031 20.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 AET38871.1 - 3.4e-08 33.4 0.1 1.7e-05 24.9 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AET38871.1 - 4.2e-08 33.4 0.1 1.4e-07 31.8 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) PPTA PF01239.17 AET38872.1 - 6e-35 117.1 14.4 4.1e-08 32.2 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DSPc PF00782.15 AET38873.1 - 2.1e-25 88.8 1.3 2.6e-24 85.3 0.9 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AET38873.1 - 0.00079 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AET38873.1 - 0.0017 18.3 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate UPF0302 PF08864.5 AET38873.1 - 0.1 12.4 0.1 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 UPF0302 domain Yippee-Mis18 PF03226.9 AET38873.1 - 0.1 12.6 1.0 0.58 10.2 0.7 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Apc15p PF05841.6 AET38874.1 - 1.7e-14 54.6 1.9 2.2e-14 54.2 0.7 1.7 2 0 0 2 2 2 1 Apc15p protein DUF1748 PF08520.5 AET38875.1 - 4.8e-21 74.1 0.1 6.6e-21 73.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) CCSMST1 PF15013.1 AET38875.1 - 0.024 14.5 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 CCSMST1 family WD40 PF00400.27 AET38876.1 - 3.6e-14 52.0 0.0 3.5e-05 23.5 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 AET38876.1 - 2.1e-05 24.3 0.0 0.017 14.8 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 AET38876.1 - 0.12 10.6 0.0 4.2 5.5 0.0 2.7 2 2 1 3 3 3 0 Cytochrome D1 heme domain AAA_12 PF13087.1 AET38877.1 - 1.7e-58 197.3 0.1 3.7e-58 196.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AET38877.1 - 1.3e-51 175.4 0.1 2.9e-51 174.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AET38877.1 - 6.3e-15 54.6 0.0 6.9e-13 48.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 AET38877.1 - 1.3e-09 37.9 0.0 3e-07 30.1 0.0 2.7 2 1 1 3 3 3 1 AAA domain UvrD-helicase PF00580.16 AET38877.1 - 4.9e-08 32.6 0.0 1.5e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 AET38877.1 - 7e-07 28.9 0.2 0.37 10.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 AET38877.1 - 9.7e-07 28.2 0.0 4.1e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 AET38877.1 - 2.4e-05 23.9 1.0 0.00042 19.8 0.1 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 AET38877.1 - 6.7e-05 22.7 0.0 0.00034 20.5 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 AET38877.1 - 9.2e-05 22.1 0.0 0.0006 19.4 0.0 2.5 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 AET38877.1 - 0.00018 21.6 0.0 0.0016 18.5 0.0 2.7 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 AET38877.1 - 0.00044 19.7 0.0 0.0013 18.1 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.7 AET38877.1 - 0.00059 19.3 0.0 0.0016 17.9 0.0 1.8 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) UvrD_C_2 PF13538.1 AET38877.1 - 0.0016 18.5 0.0 0.0053 16.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.4 AET38877.1 - 0.0043 15.7 0.0 0.0096 14.5 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 AET38877.1 - 0.0064 15.4 0.1 0.015 14.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein PIF1 PF05970.9 AET38877.1 - 0.0071 15.3 0.0 0.21 10.4 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.4 AET38877.1 - 0.0079 15.2 0.2 0.037 13.0 0.1 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 AET38877.1 - 0.016 15.1 1.1 0.22 11.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 AET38877.1 - 0.017 15.3 0.0 0.086 13.0 0.0 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AET38877.1 - 0.018 15.0 0.0 0.071 13.0 0.0 2.2 2 0 0 2 2 1 0 AAA ATPase domain AAA_25 PF13481.1 AET38877.1 - 0.018 14.4 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AET38877.1 - 0.02 15.1 1.4 3 8.1 0.4 3.4 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AET38877.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 AET38877.1 - 0.028 13.5 0.0 0.061 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF853 PF05872.7 AET38877.1 - 0.052 11.8 0.0 0.091 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MobB PF03205.9 AET38877.1 - 0.071 12.8 0.1 1 9.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AET38877.1 - 0.084 12.3 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 AET38877.1 - 0.085 12.5 0.0 0.29 10.7 0.0 1.9 1 0 0 1 1 1 0 NACHT domain ArgK PF03308.11 AET38877.1 - 0.093 11.4 0.5 0.36 9.5 0.0 1.9 2 0 0 2 2 2 0 ArgK protein Flavi_DEAD PF07652.9 AET38877.1 - 0.15 11.7 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_17 PF13207.1 AET38877.1 - 0.6 10.9 3.7 0.75 10.6 0.5 2.9 3 1 0 3 3 1 0 AAA domain Mt_ATP-synt_D PF05873.7 AET38878.1 - 5.8e-15 55.2 2.6 7.2e-15 54.9 1.8 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) IFT57 PF10498.4 AET38878.1 - 0.015 14.0 3.7 0.019 13.7 2.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Dor1 PF04124.7 AET38878.1 - 0.074 11.4 1.8 0.092 11.1 1.2 1.2 1 0 0 1 1 1 0 Dor1-like family DltD_M PF04918.7 AET38878.1 - 0.099 12.8 1.8 0.16 12.1 1.0 1.6 1 1 1 2 2 2 0 DltD central region DUF2408 PF10303.4 AET38878.1 - 0.22 11.6 3.3 0.72 9.9 2.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Tropomyosin_1 PF12718.2 AET38878.1 - 3.1 7.6 10.2 8.9 6.1 3.0 2.2 1 1 1 2 2 2 0 Tropomyosin like Fungal_trans PF04082.13 AET38879.1 - 3.6e-21 75.2 0.4 6.5e-21 74.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET38879.1 - 2.2e-10 40.2 7.0 4.5e-10 39.2 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BT1 PF03092.11 AET38879.1 - 0.0038 16.0 0.1 0.006 15.3 0.1 1.3 1 0 0 1 1 1 1 BT1 family Spc24 PF08286.6 AET38879.1 - 1.2 8.8 5.8 8.9 6.0 0.5 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Npa1 PF11707.3 AET38880.1 - 4.9e-94 315.0 7.6 4.9e-94 315.0 5.3 2.8 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal DUF3811 PF11656.3 AET38881.1 - 0.096 12.7 0.3 0.22 11.6 0.2 1.6 1 0 0 1 1 1 0 YjbD family (DUF3811) Fungal_trans PF04082.13 AET38882.1 - 6.9e-27 93.9 2.4 6.9e-27 93.9 1.6 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET38882.1 - 8.6e-05 22.3 7.1 0.00018 21.3 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YusW PF14039.1 AET38882.1 - 0.018 15.2 1.0 0.14 12.4 0.1 2.4 2 0 0 2 2 2 0 YusW-like protein ARPC4 PF05856.7 AET38883.1 - 1.8e-68 229.1 7.1 2.1e-68 229.0 4.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FF PF01846.14 AET38884.1 - 1.3e-38 130.7 17.5 1.6e-14 53.5 0.0 6.2 5 1 1 6 6 6 4 FF domain WW PF00397.21 AET38884.1 - 3e-17 62.1 18.3 2.2e-12 46.5 0.8 3.2 3 0 0 3 3 3 2 WW domain Allexi_40kDa PF05549.6 AET38884.1 - 0.0046 16.2 3.8 0.011 15.0 0.1 2.3 2 0 0 2 2 2 1 Allexivirus 40kDa protein Peptidase_S24 PF00717.18 AET38885.1 - 1e-08 34.6 0.1 2.1e-08 33.6 0.1 1.5 1 1 0 1 1 1 1 Peptidase S24-like NAD_binding_10 PF13460.1 AET38886.1 - 5.8e-26 91.6 0.0 6.7e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AET38886.1 - 2.6e-08 32.9 0.1 3.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 AET38886.1 - 5.9e-08 32.2 0.0 2.3e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 AET38886.1 - 4.1e-06 27.0 0.0 7.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 AET38886.1 - 0.0015 18.4 0.0 0.0033 17.3 0.0 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 AET38886.1 - 0.0036 16.7 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glycos_transf_1 PF00534.15 AET38886.1 - 0.037 13.4 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ydc2-catalyt PF09159.5 AET38887.1 - 1.4e-43 149.3 0.1 1.9e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 AET38887.1 - 0.002 18.0 1.0 0.053 13.4 0.1 3.0 2 1 0 2 2 2 1 Poxvirus A22 protein PGA2 PF07543.7 AET38888.1 - 1.8 8.3 5.5 0.24 11.2 0.2 2.1 3 0 0 3 3 3 0 Protein trafficking PGA2 zf-Tim10_DDP PF02953.10 AET38889.1 - 8.6e-24 82.6 3.6 1e-23 82.3 2.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 AET38889.1 - 0.0096 15.5 0.2 0.015 14.8 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase DUF842 PF05811.8 AET38889.1 - 0.027 13.9 3.4 0.036 13.5 2.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Macin PF14865.1 AET38889.1 - 0.057 13.5 0.4 0.086 12.9 0.3 1.3 1 0 0 1 1 1 0 Macin Cyto_heme_lyase PF01265.12 AET38890.1 - 2.1e-77 260.2 0.1 2.4e-77 260.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase G-alpha PF00503.15 AET38891.1 - 7.6e-119 396.8 1.6 9.5e-119 396.5 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AET38891.1 - 4.3e-15 55.3 1.4 3.7e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 AET38891.1 - 0.00016 22.1 0.1 0.14 12.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 AET38891.1 - 0.00064 18.9 2.2 0.017 14.2 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AET38891.1 - 0.015 15.2 0.0 6 6.8 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AET38891.1 - 0.054 12.9 0.1 2.1 7.7 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 AET38891.1 - 0.086 12.3 0.2 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ParBc PF02195.13 AET38892.1 - 2.8e-14 52.9 0.0 3.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Ldh_1_C PF02866.13 AET38893.1 - 3e-51 173.5 0.0 4.4e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 AET38893.1 - 4.2e-43 146.5 0.0 5.7e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AET38893.1 - 0.00014 20.6 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 AET38893.1 - 0.00093 18.5 0.0 0.062 12.6 0.0 2.3 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 AET38893.1 - 0.013 14.5 1.2 0.45 9.5 0.2 2.8 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-CHY PF05495.7 AET38894.1 - 6.4e-13 48.6 13.5 1.1e-12 47.9 9.2 1.5 1 1 0 1 1 1 1 CHY zinc finger Tmemb_55A PF09788.4 AET38894.1 - 0.0092 15.1 3.5 0.012 14.8 2.4 1.1 1 0 0 1 1 1 1 Transmembrane protein 55A zf-C3HC4_3 PF13920.1 AET38894.1 - 4.6 6.9 15.4 1.4e+03 -1.0 10.7 2.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 AET38894.1 - 6.5 6.3 8.3 7.8 6.0 1.6 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif HypA PF01155.14 AET38894.1 - 7 6.3 8.5 49 3.6 5.7 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ank_2 PF12796.2 AET38895.1 - 1e-24 86.6 1.2 7.7e-17 61.4 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AET38895.1 - 2.3e-20 71.2 7.6 4.7e-06 26.1 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 AET38895.1 - 7.2e-19 67.7 3.3 5e-06 26.8 0.2 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 AET38895.1 - 2.5e-15 56.1 0.7 1.1e-06 28.6 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET38895.1 - 8.8e-15 53.3 2.6 0.0044 17.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat TUG-UBL1 PF11470.3 AET38896.1 - 1.8e-13 50.1 0.1 5e-13 48.7 0.1 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 AET38896.1 - 1.2e-11 44.5 0.1 3.7e-11 42.9 0.1 1.9 1 0 0 1 1 1 1 UBX domain SURF6 PF04935.7 AET38898.1 - 1.1e-52 178.4 54.4 1.1e-52 178.4 37.7 2.7 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 AET38898.1 - 3.1e-18 65.5 7.5 3.1e-18 65.5 5.2 7.1 4 2 1 5 5 5 2 60S ribosome biogenesis protein Rrp14 CX PF01705.14 AET38898.1 - 0.1 12.5 0.0 0.1 12.5 0.0 3.1 3 0 0 3 3 3 0 CX module SlyX PF04102.7 AET38898.1 - 1.4 9.3 9.1 2.6 8.4 1.3 3.6 1 1 1 2 2 2 0 SlyX EF1G PF00647.14 AET38899.1 - 1.8e-45 153.0 0.1 3.3e-45 152.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 AET38899.1 - 1e-07 31.8 0.0 1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AET38899.1 - 1.2e-06 28.5 0.0 3.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AET38899.1 - 0.00024 21.2 0.0 0.00067 19.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AET38899.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain V-ATPase_C PF03223.10 AET38900.1 - 7.6e-118 393.6 5.0 8.6e-118 393.4 3.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C RasGAP PF00616.14 AET38900.1 - 0.023 14.3 0.3 0.045 13.4 0.2 1.4 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Kinesin PF00225.18 AET38901.1 - 2.3e-102 342.1 1.3 3.4e-102 341.5 0.9 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF904 PF06005.7 AET38901.1 - 1.3 9.3 16.8 0.061 13.6 1.7 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Nup54 PF13874.1 AET38901.1 - 6.9 6.3 12.7 11 5.7 3.2 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Endonuclease_NS PF01223.18 AET38902.1 - 1.6e-56 191.2 0.0 1.9e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Toxin_22 PF08092.6 AET38902.1 - 0.13 12.1 0.2 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Magi peptide toxin family Tht1 PF04163.7 AET38903.1 - 4.8e-46 157.2 16.0 4e-39 134.4 0.9 2.1 1 1 1 2 2 2 2 Tht1-like nuclear fusion protein Spc7 PF08317.6 AET38903.1 - 0.0001 21.0 3.7 0.00045 18.9 1.5 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein Apolipoprotein PF01442.13 AET38903.1 - 0.00011 21.7 0.1 0.0011 18.4 0.3 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Filament PF00038.16 AET38903.1 - 0.00053 19.5 4.1 0.00053 19.5 2.8 1.5 2 0 0 2 2 1 1 Intermediate filament protein DUF1043 PF06295.7 AET38903.1 - 0.00062 19.4 4.3 0.0039 16.8 2.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) Reo_sigmaC PF04582.7 AET38903.1 - 0.00095 18.4 1.0 0.16 11.1 0.1 2.4 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Prominin PF05478.6 AET38903.1 - 0.0021 15.7 1.3 0.012 13.1 0.3 2.1 2 0 0 2 2 2 1 Prominin Phasin PF05597.6 AET38903.1 - 0.0051 16.5 3.3 0.2 11.3 0.8 2.7 3 0 0 3 3 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DGCR6 PF07324.6 AET38903.1 - 0.0068 15.9 0.5 0.013 15.0 0.4 1.5 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Lge1 PF11488.3 AET38903.1 - 0.013 15.7 3.3 0.41 10.8 1.5 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 AAA_32 PF13654.1 AET38903.1 - 0.021 13.4 1.5 0.042 12.5 1.1 1.4 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 AET38903.1 - 0.024 14.4 11.6 0.13 12.0 1.0 3.5 2 1 2 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_MT_bd PF06657.8 AET38903.1 - 0.026 14.4 1.4 0.026 14.4 0.9 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.7 AET38903.1 - 0.028 14.2 5.5 0.37 10.5 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Glutaredoxin2_C PF04399.8 AET38903.1 - 0.065 12.8 2.1 11 5.6 0.0 2.9 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Laminin_II PF06009.7 AET38903.1 - 0.078 12.7 1.9 0.65 9.7 0.6 2.4 2 0 0 2 2 2 0 Laminin Domain II TBPIP PF07106.8 AET38903.1 - 0.11 12.0 7.3 0.17 11.4 3.7 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Matrilin_ccoil PF10393.4 AET38903.1 - 0.22 10.9 6.2 3 7.3 0.4 3.2 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin SF-assemblin PF06705.6 AET38903.1 - 0.23 10.5 9.8 0.31 10.1 3.7 2.6 1 1 0 2 2 2 0 SF-assemblin/beta giardin Phage_GP20 PF06810.6 AET38903.1 - 0.26 10.7 9.1 0.15 11.4 4.2 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Fzo_mitofusin PF04799.8 AET38903.1 - 0.34 10.2 2.7 4.3 6.6 1.2 2.5 2 0 0 2 2 2 0 fzo-like conserved region Sec5 PF15469.1 AET38903.1 - 0.39 10.4 9.6 0.16 11.6 2.2 2.7 1 1 2 3 3 3 0 Exocyst complex component Sec5 DASH_Dam1 PF08653.5 AET38903.1 - 0.54 10.0 3.2 28 4.5 0.3 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 Syntaxin-6_N PF09177.6 AET38903.1 - 1.9 8.9 7.0 9.3 6.7 2.7 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 AET38903.1 - 2.7 7.9 12.0 10 6.1 3.4 3.3 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.7 AET38903.1 - 3.4 8.0 6.5 20 5.6 2.5 3.0 2 1 0 2 2 2 0 SlyX YtxH PF12732.2 AET38903.1 - 7.5 7.0 6.9 10 6.6 2.9 2.5 2 1 0 2 2 2 0 YtxH-like protein DUF848 PF05852.6 AET38903.1 - 8.8 6.1 10.8 7.5 6.3 4.3 2.5 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SUR7 PF06687.7 AET38904.1 - 7.3e-31 107.3 18.1 8.8e-31 107.1 12.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family HA2 PF04408.18 AET38905.1 - 8.7e-19 67.4 0.1 2.9e-18 65.7 0.1 1.8 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AET38905.1 - 8.5e-17 61.0 0.0 1.7e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AET38905.1 - 7.3e-14 51.3 0.0 2.9e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AET38905.1 - 1.6e-09 37.5 0.4 6.2e-09 35.5 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AET38905.1 - 1.2e-05 25.4 0.1 2.7e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 AET38905.1 - 0.0011 18.4 0.1 0.0046 16.4 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 AET38905.1 - 0.0018 17.7 0.0 2.8 7.3 0.0 2.9 2 1 1 3 3 3 2 AAA-like domain AAA_29 PF13555.1 AET38905.1 - 0.0029 17.0 0.0 0.0073 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AET38905.1 - 0.032 14.5 0.3 0.11 12.7 0.2 1.9 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 AET38905.1 - 0.04 13.1 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 AET38905.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 AET38905.1 - 0.063 13.1 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 AET38905.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.1 AET38905.1 - 0.18 11.3 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 AET38906.1 - 1.3e-118 396.4 17.6 1.6e-118 396.1 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET38906.1 - 9.4e-30 103.5 21.8 2.6e-23 82.3 3.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AET38906.1 - 0.00014 20.1 0.5 0.00037 18.8 0.3 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 AET38906.1 - 0.00093 17.6 19.5 0.0025 16.3 4.7 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2938 PF11158.3 AET38906.1 - 0.027 13.8 0.8 0.052 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2938) OppC_N PF12911.2 AET38906.1 - 2.1 7.7 4.8 0.72 9.2 0.1 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C ArgJ PF01960.13 AET38907.1 - 2.2e-142 474.0 2.8 2.6e-142 473.8 2.0 1.0 1 0 0 1 1 1 1 ArgJ family Suf PF05843.9 AET38908.1 - 4e-71 240.0 21.9 2.6e-63 214.3 5.3 4.6 4 1 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_17 PF13431.1 AET38908.1 - 0.0035 17.4 0.9 0.17 12.1 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 AET38908.1 - 0.016 15.5 0.1 0.46 10.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Tom37_C PF11801.3 AET38909.1 - 7.4e-39 133.3 2.6 9.9e-39 132.8 1.8 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 AET38909.1 - 2.2e-19 69.5 0.2 5.6e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Sen15 PF09631.5 AET38910.1 - 6.3e-27 93.7 0.0 8.5e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein DUF4448 PF14610.1 AET38911.1 - 3.2e-54 183.2 0.5 5.5e-54 182.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) BOP1NT PF08145.7 AET38912.1 - 0.011 15.5 1.0 0.022 14.5 0.7 1.5 1 1 0 1 1 1 0 BOP1NT (NUC169) domain TryThrA_C PF12319.3 AET38912.1 - 0.011 14.9 2.8 0.019 14.1 1.9 1.3 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Cu-oxidase_2 PF07731.9 AET38913.1 - 5.9e-45 152.1 9.7 1.1e-39 135.0 0.6 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 AET38913.1 - 2.2e-41 140.3 3.1 3.2e-38 130.0 0.1 3.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 AET38913.1 - 5e-33 114.2 7.2 2.8e-32 111.7 0.6 3.8 4 1 1 5 5 5 1 Multicopper oxidase C1q PF00386.16 AET38913.1 - 0.049 13.6 0.0 0.24 11.4 0.0 2.2 1 0 0 1 1 1 0 C1q domain RabGAP-TBC PF00566.13 AET38914.1 - 3.3e-36 124.7 0.0 5.7e-36 123.9 0.0 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 AET38915.1 - 0.053 13.1 0.0 0.18 11.4 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease PF00324.16 AET38916.1 - 6e-118 394.2 30.3 6.8e-118 394.0 21.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET38916.1 - 1.8e-22 79.4 29.9 2.3e-22 79.1 20.5 1.3 1 1 0 1 1 1 1 Amino acid permease DUF1712 PF08217.6 AET38918.1 - 6.6e-172 572.9 9.6 8.3e-172 572.5 6.6 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) SRP54 PF00448.17 AET38919.1 - 4.9e-79 264.3 0.6 4.9e-79 264.3 0.4 2.2 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 AET38919.1 - 7.3e-26 90.4 9.3 7.3e-26 90.4 6.4 4.5 4 1 1 5 5 5 1 Signal peptide binding domain SRP54_N PF02881.14 AET38919.1 - 2e-10 40.6 4.7 6.3e-10 39.0 3.3 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 AET38919.1 - 1.6e-06 27.6 1.5 1.8e-05 24.2 0.3 2.8 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 AET38919.1 - 5.7e-06 26.2 0.0 2.7e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 AET38919.1 - 1.6e-05 24.3 1.1 5.1e-05 22.7 0.1 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 AET38919.1 - 3.3e-05 23.6 0.1 9.6e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 AET38919.1 - 3.9e-05 23.6 0.2 0.038 13.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 AET38919.1 - 0.00088 18.8 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 AET38919.1 - 0.0009 20.0 0.0 0.0018 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain VirE PF05272.6 AET38919.1 - 0.0012 18.3 0.1 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 Virulence-associated protein E AAA_18 PF13238.1 AET38919.1 - 0.0047 17.2 0.3 0.042 14.1 0.0 2.7 3 1 0 3 3 2 1 AAA domain APS_kinase PF01583.15 AET38919.1 - 0.0086 15.7 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.5 AET38919.1 - 0.014 14.5 6.6 1.2 8.3 0.1 4.1 3 2 1 4 4 4 0 Signal recognition particle receptor beta subunit ArgK PF03308.11 AET38919.1 - 0.016 14.0 1.0 0.05 12.3 0.0 2.3 2 1 0 2 2 2 0 ArgK protein AAA_22 PF13401.1 AET38919.1 - 0.018 15.1 0.2 0.12 12.5 0.1 2.6 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.1 AET38919.1 - 0.019 14.5 0.1 0.07 12.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain Arf PF00025.16 AET38919.1 - 0.03 13.5 0.1 0.65 9.2 0.0 2.9 2 1 0 2 2 2 0 ADP-ribosylation factor family G-alpha PF00503.15 AET38919.1 - 0.075 11.7 3.0 4 6.0 0.2 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 AET38919.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 AET38919.1 - 1.9 8.1 7.7 7.8 6.1 1.6 3.2 2 1 0 2 2 2 0 NTPase TMF_DNA_bd PF12329.3 AET38920.1 - 0.00023 20.8 6.5 0.00023 20.8 4.5 3.4 3 2 0 3 3 3 1 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 AET38920.1 - 0.0097 14.6 17.6 0.015 13.9 12.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 AET38920.1 - 0.045 13.3 22.5 0.018 14.6 8.2 2.2 1 1 1 2 2 2 0 IncA protein Synaptobrevin PF00957.16 AET38920.1 - 0.058 12.9 0.9 0.17 11.4 0.2 2.1 1 1 0 2 2 2 0 Synaptobrevin PhaP_Bmeg PF09602.5 AET38920.1 - 0.53 10.0 16.3 0.37 10.6 9.8 1.7 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Macoilin PF09726.4 AET38920.1 - 1 7.5 26.7 0.0022 16.3 9.2 2.2 2 1 0 2 2 2 0 Transmembrane protein APG6 PF04111.7 AET38920.1 - 1.3 8.0 23.1 1.6 7.6 8.9 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Tup_N PF08581.5 AET38920.1 - 1.4 9.1 19.4 0.096 12.8 5.2 3.3 3 1 0 3 3 3 0 Tup N-terminal ADIP PF11559.3 AET38920.1 - 2.4 8.0 24.2 0.044 13.6 6.5 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 AET38920.1 - 4 6.6 16.4 0.17 11.1 4.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.6 AET38920.1 - 4 7.3 9.5 5.5 6.9 1.2 2.9 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 AET38920.1 - 6.9 6.4 12.1 7 6.4 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PH PF00169.24 AET38921.1 - 8.4e-16 58.0 4.2 3e-08 33.8 0.5 2.6 2 0 0 2 2 2 2 PH domain PH_6 PF15406.1 AET38921.1 - 0.00027 20.9 0.0 0.72 9.9 0.0 2.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 AET38921.1 - 0.028 14.6 12.0 0.062 13.5 0.1 4.4 3 2 1 5 5 5 0 Pleckstrin homology domain PH_8 PF15409.1 AET38921.1 - 0.084 12.9 0.6 0.43 10.6 0.0 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.5 AET38921.1 - 0.11 12.3 0.1 1 9.3 0.1 2.1 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_3 PF14593.1 AET38921.1 - 0.32 10.8 4.4 1.4 8.8 0.1 2.6 2 1 0 2 2 2 0 PH domain Miro PF08477.8 AET38922.1 - 0.0097 16.3 0.0 0.048 14.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 AET38922.1 - 0.013 15.4 0.2 0.036 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 AET38922.1 - 0.024 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.18 AET38922.1 - 0.036 14.0 0.0 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF463 PF04317.7 AET38922.1 - 0.055 12.0 0.0 0.11 11.0 0.0 1.4 2 0 0 2 2 2 0 YcjX-like family, DUF463 Atg14 PF10186.4 AET38923.1 - 1.1e-36 126.3 5.5 2.6e-36 125.1 3.8 1.6 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DHC PF09626.5 AET38923.1 - 1.6 9.4 4.2 0.4 11.3 0.2 2.0 2 0 0 2 2 2 0 Dihaem cytochrome c ATP-synt_ab PF00006.20 AET38924.1 - 5.2e-61 205.8 0.0 6.9e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AET38924.1 - 3.8e-16 59.5 0.2 7.8e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AET38924.1 - 2.8e-13 49.8 1.1 6.1e-13 48.7 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AET38924.1 - 0.002 18.0 0.3 0.005 16.7 0.2 1.7 1 0 0 1 1 1 1 HAS barrel domain RVT_1 PF00078.22 AET38925.1 - 0.0024 17.2 0.1 0.3 10.4 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_20 PF00982.16 AET38927.1 - 1e-198 660.6 0.1 1.2e-198 660.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 AET38927.1 - 0.00093 18.6 0.3 0.18 11.2 0.1 2.9 2 1 0 2 2 2 2 Glycosyl transferases group 1 PP2C PF00481.16 AET38928.1 - 3.6e-63 213.3 0.0 1.4e-62 211.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AET38928.1 - 0.00019 20.9 0.0 0.00057 19.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 AET38928.1 - 0.0025 17.5 0.1 0.41 10.3 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Tau95 PF09734.4 AET38929.1 - 2.1e-56 191.5 3.6 2.9e-56 191.0 2.5 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Ribosomal_L31 PF01197.13 AET38930.1 - 0.0007 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L31 Me-amine-dh_H PF06433.6 AET38930.1 - 0.047 12.3 0.0 0.06 11.9 0.0 1.1 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) DIM1 PF02966.11 AET38931.1 - 1.1e-67 225.6 0.8 1.2e-67 225.4 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 tRNA-synt_2b PF00587.20 AET38932.1 - 2.9e-70 235.3 0.1 2.2e-69 232.4 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AET38932.1 - 1.5e-21 76.1 0.1 4.2e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Atg14 PF10186.4 AET38933.1 - 0.22 10.4 1.5 0.26 10.2 1.0 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RRM_6 PF14259.1 AET38934.1 - 4.4e-08 32.9 0.1 3.7e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET38934.1 - 1.2e-07 31.2 0.1 5.6e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET38934.1 - 8e-06 25.6 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 AET38934.1 - 0.11 12.5 5.9 0.061 13.3 1.5 2.1 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RecX PF02631.11 AET38934.1 - 0.13 12.4 2.2 0.25 11.5 0.4 2.3 1 1 1 2 2 2 0 RecX family GTP_EFTU PF00009.22 AET38935.1 - 1.2e-57 194.3 0.0 1.7e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AET38935.1 - 1.1e-35 121.7 0.0 3.7e-35 120.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AET38935.1 - 5.4e-17 61.6 1.5 5.4e-17 61.6 1.1 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AET38935.1 - 2.2e-05 24.0 0.5 2.2e-05 24.0 0.3 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 AET38935.1 - 0.0011 18.9 0.2 0.0032 17.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Opy2 PF09463.5 AET38937.1 - 6.8e-08 32.4 22.1 1e-07 31.9 15.3 1.3 1 0 0 1 1 1 1 Opy2 protein Yip1 PF04893.12 AET38937.1 - 0.03 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Adeno_E3_CR2 PF02439.10 AET38937.1 - 0.034 13.7 0.1 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gly-zipper_Omp PF13488.1 AET38937.1 - 0.054 13.1 15.2 0.21 11.2 2.9 2.6 2 0 0 2 2 2 0 Glycine zipper Syndecan PF01034.15 AET38937.1 - 0.058 13.0 0.1 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Syndecan domain EPV_E5 PF08135.6 AET38937.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Major transforming protein E5 family Gly-zipper_OmpA PF13436.1 AET38937.1 - 0.085 12.5 3.8 6.4 6.4 0.4 2.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 AET38937.1 - 0.52 10.0 15.4 0.7 9.6 1.4 2.7 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 AET38937.1 - 0.82 9.2 18.7 0.36 10.3 1.9 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Transketolase_N PF00456.16 AET38938.1 - 7.5e-150 498.3 0.0 1.1e-149 497.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 AET38938.1 - 1.8e-45 154.6 0.0 3.6e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AET38938.1 - 1.6e-14 53.8 0.0 3.2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 AET38938.1 - 0.00024 20.1 0.0 0.041 12.8 0.0 2.6 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase LMWPc PF01451.16 AET38939.1 - 2.2e-39 134.9 0.0 2.5e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase S_tail_recep_bd PF14928.1 AET38939.1 - 0.054 13.7 0.9 4.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Short tail fibre protein receptor-binding domain Not3 PF04065.10 AET38940.1 - 3.1e-79 265.5 33.7 4.4e-57 193.0 14.2 2.2 1 1 1 2 2 2 2 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 AET38940.1 - 2.4e-38 131.0 0.5 8.8e-38 129.2 0.3 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CK2S PF15011.1 AET38940.1 - 0.33 10.7 4.7 0.28 10.9 0.5 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate Cep57_MT_bd PF06657.8 AET38940.1 - 1.5 8.8 11.7 0.2 11.6 3.0 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 tRNA-synt_1g PF09334.6 AET38940.1 - 1.8 7.0 7.2 4 6.0 5.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (M) L31 PF09784.4 AET38940.1 - 3.6 7.6 8.8 35 4.5 0.3 3.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 AMP-binding PF00501.23 AET38941.1 - 8.7e-72 241.7 0.0 1.2e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 AET38941.1 - 5.2e-69 231.9 0.0 7.4e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 AET38941.1 - 3.1e-15 56.1 0.0 7.5e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 AET38941.1 - 4.5e-14 52.4 0.0 8.7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AET38941.1 - 8.5e-09 34.5 0.0 1.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 AET38941.1 - 2.1e-07 31.7 0.0 9.7e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 AET38941.1 - 0.0015 18.5 0.0 0.033 14.1 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding ATG19_autophagy PF12744.2 AET38941.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding RmlD_sub_bind PF04321.12 AET38941.1 - 0.37 9.6 0.0 2 7.2 0.0 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain SNF2_N PF00176.18 AET38942.1 - 8.5e-76 254.5 0.1 1.5e-75 253.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AET38942.1 - 1.3e-10 40.9 0.0 2.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 AET38942.1 - 1.1e-07 31.3 10.0 1.1e-07 31.3 7.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 AET38942.1 - 4.5e-05 23.0 0.0 9.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 AET38942.1 - 0.00012 22.0 9.4 0.00012 22.0 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET38942.1 - 0.00034 20.3 10.4 0.00034 20.3 7.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 AET38942.1 - 0.0021 17.8 9.2 0.0021 17.8 6.4 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 AET38942.1 - 0.0029 17.2 8.1 0.0029 17.2 5.6 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 AET38942.1 - 0.031 14.0 2.8 0.086 12.6 1.9 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein SnAC PF14619.1 AET38942.1 - 0.097 12.8 1.0 0.29 11.3 0.7 1.8 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex SRF-TF PF00319.13 AET38942.1 - 0.13 11.5 2.4 3.9 6.7 0.0 2.6 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Zn_Tnp_IS91 PF14319.1 AET38942.1 - 0.72 9.3 12.1 0.67 9.4 2.0 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Spt4 PF06093.8 AET38942.1 - 7.1 6.5 10.0 0.73 9.7 2.7 2.3 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger TPR_1 PF00515.23 AET38943.1 - 2.8e-48 159.6 19.4 2.2e-07 30.1 0.0 10.2 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 AET38943.1 - 4.5e-43 144.7 24.8 6.7e-11 41.6 0.6 6.6 2 2 3 6 6 6 6 TPR repeat TPR_2 PF07719.12 AET38943.1 - 6.8e-42 138.0 22.7 0.00013 21.5 0.0 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 AET38943.1 - 1.2e-28 96.9 23.3 0.00077 19.4 0.1 11.5 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 AET38943.1 - 4.6e-28 97.2 24.2 1.7e-06 28.5 0.1 6.7 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 AET38943.1 - 1.6e-27 93.1 14.1 0.06 13.1 0.0 9.7 7 1 2 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 AET38943.1 - 1.8e-27 95.1 33.7 5.8e-08 32.5 0.4 7.7 2 2 7 9 9 9 9 Tetratricopeptide repeat TPR_14 PF13428.1 AET38943.1 - 1.5e-23 81.1 23.0 0.013 16.1 0.0 10.3 2 2 8 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 AET38943.1 - 2.6e-19 67.4 19.4 0.0012 18.4 0.2 9.4 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 AET38943.1 - 2.4e-16 59.8 29.2 0.00011 22.4 1.2 7.1 5 3 2 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 AET38943.1 - 1.5e-13 50.1 25.9 0.24 11.9 0.0 10.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 AET38943.1 - 9e-12 44.6 19.9 6.2e-05 22.7 0.0 6.1 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_15 PF13429.1 AET38943.1 - 9e-05 21.6 35.8 0.0016 17.5 0.1 5.5 2 1 2 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 AET38943.1 - 0.67 9.9 29.8 0.05 13.5 0.6 7.8 7 2 2 9 9 9 0 Tetratricopeptide repeat Peptidase_M16 PF00675.15 AET38943.1 - 9.9 5.8 11.9 2.4 7.8 4.5 2.4 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) EnY2 PF10163.4 AET38944.1 - 8.6e-28 96.1 1.3 9.9e-28 95.9 0.9 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Vmethyltransf_C PF08456.5 AET38944.1 - 0.033 13.6 0.4 0.039 13.3 0.3 1.2 1 1 0 1 1 1 0 Viral methyltransferase C-terminal DUF3887 PF13026.1 AET38944.1 - 0.035 14.3 0.5 0.045 14.0 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3887) USP8_interact PF08941.5 AET38944.1 - 0.062 12.6 0.0 0.069 12.4 0.0 1.1 1 0 0 1 1 1 0 USP8 interacting NUDIX PF00293.23 AET38945.1 - 1.2e-21 76.8 0.0 1.3e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain TAT_ubiq PF07706.7 AET38945.1 - 0.035 14.0 0.4 0.066 13.1 0.3 1.4 1 0 0 1 1 1 0 Aminotransferase ubiquitination site Med1 PF10744.4 AET38946.1 - 2.1e-62 211.1 5.5 1.3e-59 201.9 3.8 2.1 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Spermine_synth PF01564.12 AET38947.1 - 1.1e-89 299.6 0.0 1.3e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_30 PF05430.6 AET38947.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Hist_deacetyl PF00850.14 AET38948.1 - 4e-65 220.1 0.0 5.7e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_trans_1_4 PF13692.1 AET38949.1 - 1e-13 51.5 0.0 3.5e-13 49.8 0.0 1.9 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 AET38949.1 - 1.4e-11 44.1 0.0 2.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AET38949.1 - 1.1e-06 28.8 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 AET38949.1 - 0.0074 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 EF-hand_1 PF00036.27 AET38950.1 - 1.9e-29 98.7 3.6 1.7e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AET38950.1 - 4.4e-26 90.7 0.4 1.4e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AET38950.1 - 6.4e-25 84.7 2.5 6.3e-08 31.8 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 AET38950.1 - 2.3e-18 65.5 4.7 4.6e-08 32.5 0.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 AET38950.1 - 1.5e-16 58.8 4.6 1.9e-07 30.1 0.0 4.3 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 AET38950.1 - 3.9e-12 45.8 0.0 3.2e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 AET38950.1 - 1.3e-05 25.2 0.2 0.0043 17.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 AET38950.1 - 2e-05 24.1 0.0 0.33 10.6 0.0 2.9 3 1 0 4 4 4 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 AET38950.1 - 0.0016 18.0 0.0 0.86 9.1 0.0 2.2 2 0 0 2 2 2 2 Caleosin related protein EF-hand_4 PF12763.2 AET38950.1 - 0.005 16.5 0.2 0.016 14.9 0.1 1.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 AET38950.1 - 0.013 13.9 0.2 0.035 12.4 0.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TerB PF05099.8 AET38950.1 - 0.014 15.1 0.1 0.73 9.5 0.0 2.2 2 1 0 2 2 2 0 Tellurite resistance protein TerB ERAP1_C PF11838.3 AET38950.1 - 0.071 12.3 0.1 0.1 11.8 0.1 1.3 1 1 0 1 1 1 0 ERAP1-like C-terminal domain RNA_pol_Rpb4 PF03874.11 AET38950.1 - 0.11 12.4 0.9 0.78 9.7 0.0 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 Fe-S_biosyn PF01521.15 AET38953.1 - 2.1e-14 53.4 0.1 4.5e-13 49.1 0.0 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis ThiF PF00899.16 AET38954.1 - 7.3e-28 97.0 0.0 1.3e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 AET38954.1 - 3e-16 58.7 0.0 6.9e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AET38954.1 - 7.4e-08 31.6 0.5 1.5e-07 30.6 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 AET38954.1 - 0.0062 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pho88 PF10032.4 AET38955.1 - 3.2e-76 254.8 2.2 3.5e-76 254.7 1.5 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF3278 PF11683.3 AET38955.1 - 0.48 10.4 5.1 0.46 10.4 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) ER_lumen_recept PF00810.13 AET38955.1 - 4.8 7.6 8.5 14 6.1 5.9 1.6 1 1 1 2 2 2 0 ER lumen protein retaining receptor HMG_box PF00505.14 AET38956.1 - 4.4e-14 52.4 5.7 2.1e-13 50.3 3.9 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AET38956.1 - 5.1e-09 36.3 0.8 5.1e-09 36.3 0.6 2.8 3 1 0 3 3 3 1 HMG-box domain Med15 PF09606.5 AET38956.1 - 0.037 12.2 75.7 0.063 11.4 52.5 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4145 PF13643.1 AET38956.1 - 0.042 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Vac_ImportDeg PF09783.4 AET38957.1 - 7.6e-67 224.2 2.4 1e-66 223.8 1.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0139 PF03669.8 AET38958.1 - 0.023 14.2 2.6 0.058 12.9 1.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0139) DnaJ PF00226.26 AET38959.1 - 2.7e-16 59.0 0.3 5.3e-16 58.1 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain CM_2 PF01817.16 AET38960.1 - 2.8e-10 40.1 0.0 7.3e-07 29.1 0.0 3.6 2 1 0 2 2 2 2 Chorismate mutase type II SIP1 PF04938.7 AET38961.1 - 0.0066 15.8 0.3 0.022 14.1 0.2 2.1 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF4259 PF14078.1 AET38961.1 - 0.015 15.7 0.5 0.1 13.1 0.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) zf-C2H2_4 PF13894.1 AET38962.1 - 0.00079 19.5 0.1 0.00079 19.5 0.1 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AET38962.1 - 0.0085 16.3 2.1 0.018 15.3 0.1 2.4 1 1 1 2 2 2 1 Zinc finger, C2H2 type Tfb4 PF03850.9 AET38963.1 - 6e-104 347.1 0.3 6.9e-104 346.9 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 AET38963.1 - 0.00046 20.3 0.0 0.00067 19.8 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Rad50_zn_hook PF04423.9 AET38963.1 - 0.44 10.0 2.5 2.2 7.8 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif WD40 PF00400.27 AET38964.1 - 2.9e-30 103.0 7.9 8.6e-07 28.6 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat LisH PF08513.6 AET38964.1 - 4.5e-09 35.7 0.2 8.4e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 AET38964.1 - 5.6e-06 26.2 1.1 0.00053 19.7 0.2 3.5 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Vps51 PF08700.6 AET38965.1 - 4.7e-10 39.1 0.8 4.7e-10 39.1 0.5 2.2 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 AET38965.1 - 0.0088 15.9 0.4 0.0088 15.9 0.3 3.0 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 RP-C_C PF11800.3 AET38965.1 - 1.3 8.6 7.2 2 8.1 0.8 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region UFD1 PF03152.9 AET38966.1 - 5e-05 22.5 0.0 0.13 11.3 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 Sgf11 PF08209.6 AET38966.1 - 0.087 12.1 0.0 0.087 12.1 0.0 2.8 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-C2H2_6 PF13912.1 AET38966.1 - 0.33 10.9 0.1 0.33 10.9 0.0 4.3 5 0 0 5 5 5 0 C2H2-type zinc finger Fes1 PF08609.5 AET38967.1 - 5.6e-29 100.4 1.0 1.5e-28 99.1 0.7 1.8 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 AET38967.1 - 0.00028 21.1 0.0 0.019 15.2 0.0 2.8 2 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 AET38967.1 - 0.073 13.1 0.0 14 6.1 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat Rad33 PF08730.5 AET38967.1 - 0.11 12.0 4.3 0.046 13.1 1.2 1.7 2 0 0 2 2 2 0 Rad33 ERCC4 PF02732.10 AET38968.1 - 3.3e-07 30.1 0.7 9.1e-07 28.7 0.5 1.8 1 0 0 1 1 1 1 ERCC4 domain Sec8_exocyst PF04048.9 AET38969.1 - 3.1e-45 153.2 0.4 3.1e-45 153.2 0.3 2.6 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Pkinase PF00069.20 AET38970.1 - 7.6e-27 94.0 0.0 1.6e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 AET38970.1 - 5.2e-12 44.7 9.6 0.0022 17.9 0.3 6.0 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 AET38970.1 - 1.3e-10 41.3 0.0 0.00072 19.7 0.0 3.1 2 1 1 3 3 3 3 HEAT repeats Pkinase_Tyr PF07714.12 AET38970.1 - 1.7e-09 37.1 0.0 4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 AET38970.1 - 0.0008 19.1 6.4 0.92 9.4 0.0 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat Kinase-like PF14531.1 AET38970.1 - 0.0013 17.7 0.0 0.011 14.6 0.0 2.3 1 1 1 2 2 2 1 Kinase-like HEAT_EZ PF13513.1 AET38970.1 - 0.0036 17.7 0.0 24 5.5 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat APH PF01636.18 AET38970.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 AET38971.1 - 6.3e-65 218.8 0.0 8.2e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET38971.1 - 3.6e-30 104.8 0.0 5.1e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET38971.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RXT2_N PF08595.6 AET38972.1 - 1.2e-40 138.7 0.1 1.2e-40 138.7 0.0 2.2 3 0 0 3 3 3 1 RXT2-like, N-terminal Upf2 PF04050.9 AET38972.1 - 0.027 14.2 2.5 0.059 13.1 1.7 1.7 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Peptidase_C6 PF00851.13 AET38972.1 - 0.066 11.8 0.2 0.13 10.8 0.1 1.5 1 0 0 1 1 1 0 Helper component proteinase zf-Tim10_DDP PF02953.10 AET38973.1 - 1.7e-16 59.2 0.2 2.4e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger LCCL PF03815.14 AET38974.1 - 1.6e-08 34.4 0.0 2.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Sec6 PF06046.8 AET38975.1 - 1.6e-158 528.2 18.6 1.6e-158 528.2 12.9 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec6 HTH_40 PF14493.1 AET38975.1 - 0.29 11.3 0.1 0.29 11.3 0.0 3.9 4 2 0 4 4 4 0 Helix-turn-helix domain Tctex-1 PF03645.8 AET38976.1 - 5.4e-09 35.8 0.0 7.6e-09 35.3 0.0 1.3 1 1 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 AET38977.1 - 1.4e-12 47.6 4.5 1.4e-12 47.6 3.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 AET38977.1 - 0.092 12.6 0.2 0.092 12.6 0.1 2.0 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF2615 PF11027.3 AET38977.1 - 5.5 6.9 5.1 4.1 7.3 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Ribosomal_S24e PF01282.14 AET38978.1 - 7e-36 121.8 0.1 1.1e-35 121.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Yos1 PF08571.5 AET38979.1 - 5.4e-31 106.5 2.3 6e-31 106.3 1.6 1.0 1 0 0 1 1 1 1 Yos1-like Y_phosphatase PF00102.22 AET38980.1 - 1.6e-53 181.4 0.1 2.8e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 AET38980.1 - 2.5e-11 43.9 0.1 1.6e-10 41.2 0.0 2.4 3 0 0 3 3 3 1 Rhodanese-like domain DSPc PF00782.15 AET38980.1 - 0.00066 19.2 0.0 0.0022 17.5 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 AET38980.1 - 0.039 14.2 0.3 0.16 12.2 0.0 2.1 3 0 0 3 3 3 0 Tyrosine phosphatase family DUF2205 PF10224.4 AET38981.1 - 8.6e-05 22.0 1.6 0.00015 21.3 1.1 1.5 1 1 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Actin PF00022.14 AET38983.1 - 3.3e-25 88.3 0.1 5.4e-12 44.8 0.0 2.5 1 1 2 3 3 3 2 Actin MreB_Mbl PF06723.8 AET38983.1 - 0.095 11.2 0.9 0.16 10.5 0.5 1.6 1 1 0 1 1 1 0 MreB/Mbl protein Serinc PF03348.10 AET38984.1 - 6.9e-148 492.9 20.6 8e-148 492.6 14.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Rad51 PF08423.6 AET38985.1 - 1.4e-124 414.1 0.1 2e-124 413.6 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AET38985.1 - 7.4e-12 45.0 0.0 1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 AET38985.1 - 2.5e-09 36.6 0.0 3.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AET38985.1 - 7.5e-07 28.4 0.6 3.1e-06 26.4 0.1 2.3 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.1 AET38985.1 - 0.0001 22.4 0.2 0.00028 20.9 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain PAXNEB PF05625.6 AET38985.1 - 0.0016 17.3 0.0 0.19 10.5 0.0 2.1 2 0 0 2 2 2 2 PAXNEB protein RNA_pol_A_CTD PF03118.10 AET38985.1 - 0.013 14.9 0.1 0.028 13.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain AAA_22 PF13401.1 AET38985.1 - 0.021 14.9 0.1 0.087 12.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain Peptidase_M24 PF00557.19 AET38986.1 - 4e-07 29.8 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Metallopeptidase family M24 E1_dh PF00676.15 AET38987.1 - 1.7e-121 404.5 0.4 2.1e-121 404.2 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 AET38987.1 - 0.0036 16.2 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 AET38987.1 - 0.05 14.2 0.3 0.05 14.2 0.2 3.1 2 2 1 3 3 3 0 KRTAP type 7 family Ste5_C PF12194.3 AET38988.1 - 2.1e-70 236.2 0.7 3.6e-70 235.5 0.5 1.3 1 0 0 1 1 1 1 Protein kinase Fus3-binding zf-RING_2 PF13639.1 AET38988.1 - 0.00065 19.4 6.5 0.0016 18.1 4.5 1.8 1 0 0 1 1 1 1 Ring finger domain PH_4 PF15404.1 AET38989.1 - 4.9e-70 234.8 0.0 1.1e-69 233.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.1 AET38989.1 - 1e-23 82.5 0.3 2.6e-23 81.2 0.2 1.7 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 AET38989.1 - 6e-06 26.3 1.3 0.2 11.9 0.9 4.3 2 2 0 2 2 2 2 PH domain COPI_assoc PF08507.5 AET38990.1 - 4.5e-25 87.9 6.9 5.4e-25 87.6 4.8 1.0 1 0 0 1 1 1 1 COPI associated protein 14-3-3 PF00244.15 AET38991.1 - 6.9e-116 385.3 4.5 8e-116 385.1 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein SPACA7 PF15307.1 AET38991.1 - 0.018 15.1 3.0 1.4 9.1 0.1 2.8 2 1 0 2 2 2 0 Sperm acrosome-associated protein 7 FlaF PF07309.6 AET38991.1 - 0.022 14.6 0.1 0.06 13.2 0.1 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF DUF885 PF05960.6 AET38991.1 - 0.042 13.0 1.1 0.058 12.5 0.4 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Glutaredoxin PF00462.19 AET38992.1 - 1.1e-17 63.7 0.0 1.8e-16 59.8 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 AET38992.1 - 1.2e-12 47.4 0.0 2.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AET38992.1 - 2.7e-05 24.1 1.1 0.00019 21.4 0.0 2.4 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 AET38992.1 - 0.00054 19.6 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 AET38992.1 - 0.0036 17.4 0.2 0.071 13.3 0.0 2.7 2 2 0 2 2 2 1 Thioredoxin-like domain ArsC PF03960.10 AET38992.1 - 0.048 13.7 0.0 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 ArsC family Thioredoxin_7 PF13899.1 AET38992.1 - 0.081 12.9 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like Rad17 PF03215.10 AET38993.1 - 5.6e-93 312.3 0.4 2.1e-65 221.3 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 AET38993.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 AET38993.1 - 0.037 14.2 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_bind PF08675.6 AET38993.1 - 0.044 13.7 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 RNA binding domain AAA_17 PF13207.1 AET38993.1 - 0.099 13.4 0.0 0.32 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 AET38993.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 NTPase Sec63 PF02889.11 AET38994.1 - 9.9e-172 570.3 9.1 1.3e-89 300.5 0.3 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AET38994.1 - 1.4e-46 158.0 0.0 1.9e-29 102.2 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 AET38994.1 - 6.6e-17 61.9 0.1 4.6e-11 42.8 0.0 3.1 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AET38994.1 - 3.5e-09 36.3 0.0 2e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AET38994.1 - 3.8e-07 30.3 0.9 0.0073 16.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AET38994.1 - 0.002 17.8 0.0 0.59 9.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 AET38994.1 - 0.012 15.8 0.3 1.4 9.0 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 AET38994.1 - 0.014 14.8 0.1 2.6 7.4 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF1227 PF06777.6 AET38995.1 - 5e-56 188.4 0.5 1.4e-55 187.0 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 AET38995.1 - 3.3e-50 169.9 7.6 7.6e-50 168.7 5.3 1.7 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 AET38995.1 - 1.6e-44 151.8 0.0 5.7e-44 150.0 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 AET38995.1 - 0.00051 19.5 0.0 1.7 8.1 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase AAA_22 PF13401.1 AET38995.1 - 0.0035 17.4 1.1 17 5.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 AET38995.1 - 0.005 16.6 0.4 0.042 13.6 0.3 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AET38995.1 - 0.012 14.4 0.1 0.49 9.1 0.0 2.3 2 0 0 2 2 2 0 SNF2 family N-terminal domain YtxC PF08812.6 AET38995.1 - 0.013 14.9 3.5 0.23 10.9 0.1 3.1 3 1 0 3 3 3 0 YtxC-like family PhoH PF02562.11 AET38995.1 - 0.07 12.3 0.0 4 6.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ADK PF00406.17 AET38996.1 - 2.7e-41 140.9 0.0 3.2e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 AET38996.1 - 4.7e-13 48.5 0.0 8.5e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 AET38996.1 - 1.1e-05 25.7 0.1 3.2e-05 24.2 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AET38996.1 - 5.8e-05 23.8 0.0 0.00011 22.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AET38996.1 - 0.0097 15.7 0.4 0.068 13.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AET38996.1 - 0.039 13.0 0.0 0.086 11.9 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 AET38996.1 - 0.072 12.5 0.1 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MutS_V PF00488.16 AET38997.1 - 2.1e-78 262.9 0.1 3.8e-78 262.1 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AET38997.1 - 5.9e-38 130.6 0.0 9.3e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AET38997.1 - 9.7e-34 115.7 0.0 4.1e-33 113.7 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 AET38997.1 - 7.4e-16 58.1 0.6 1.6e-15 57.0 0.4 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 AET38997.1 - 2.6e-11 43.7 0.0 8.1e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 AET38997.1 - 0.028 13.9 0.0 0.092 12.2 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain JmjC PF02373.17 AET38998.1 - 2e-40 137.5 1.4 4.8e-40 136.3 0.9 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 AET38998.1 - 4.7e-16 58.0 1.7 1.4e-15 56.5 1.2 1.9 1 0 0 1 1 1 1 jmjN domain zf-C2H2_4 PF13894.1 AET38998.1 - 3.5e-07 30.1 12.6 0.0012 18.9 0.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AET38998.1 - 5.9e-07 29.4 7.3 5.9e-07 29.4 5.0 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 AET38998.1 - 6.9e-07 29.2 16.3 0.0015 18.7 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AET38998.1 - 0.014 15.2 11.5 0.024 14.5 3.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger HypA PF01155.14 AET38998.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 AET38998.1 - 0.53 10.2 6.5 2.9 7.9 4.5 2.2 1 1 0 1 1 1 0 Zinc ribbon domain zf-met PF12874.2 AET38998.1 - 5.7 7.2 9.6 20 5.5 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AET38998.1 - 6.7 6.9 16.9 0.16 12.1 3.4 2.9 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding ANTH PF07651.11 AET38999.1 - 1.4e-58 197.8 0.1 1.4e-58 197.8 0.0 1.8 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 AET38999.1 - 1.2e-06 28.4 0.1 9.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 ENTH domain PFK PF00365.15 AET39000.1 - 1.3e-171 569.0 2.0 6.5e-123 409.1 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 AET39000.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.6 3 0 0 3 3 3 0 UvrB/uvrC motif NTP_transf_2 PF01909.18 AET39001.1 - 2e-15 56.9 0.0 6.9e-15 55.1 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 AET39001.1 - 5e-14 51.9 0.0 1.3e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase DNA_pol_B_palm PF14792.1 AET39001.1 - 0.076 13.0 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase beta palm RF-1 PF00472.15 AET39002.1 - 1.4e-13 50.6 0.1 2.1e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 RF-1 domain Pkinase PF00069.20 AET39003.1 - 6.2e-67 225.4 0.0 9.9e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39003.1 - 5.4e-51 173.1 0.1 8.3e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 AET39003.1 - 1.4e-20 73.4 2.5 1.6e-20 73.2 0.2 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 AET39003.1 - 6.3e-10 39.1 0.7 1.4e-09 38.1 0.5 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 AET39003.1 - 2e-07 30.3 0.0 3.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 AET39003.1 - 7.2e-06 26.2 0.3 2e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 AET39003.1 - 0.018 14.7 0.2 0.018 14.7 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 AET39003.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec7_N PF12783.2 AET39004.1 - 2.4e-34 118.1 9.8 2.4e-34 118.1 6.8 5.2 6 1 0 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pet20 PF08692.5 AET39005.1 - 0.0073 16.2 0.4 0.036 14.0 0.0 2.3 3 0 0 3 3 3 1 Mitochondrial protein Pet20 PalH PF08733.5 AET39006.1 - 1.8e-77 260.5 5.3 2.3e-77 260.2 3.7 1.1 1 0 0 1 1 1 1 PalH/RIM21 ubiquitin PF00240.18 AET39007.1 - 0.00022 20.5 0.1 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 AET39007.1 - 0.019 14.8 0.3 0.032 14.0 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Erf4 PF10256.4 AET39008.1 - 1.4e-26 92.6 0.0 1.8e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TruB_N PF01509.13 AET39009.1 - 2.5e-42 144.5 0.0 1.4e-39 135.6 0.0 2.4 1 1 0 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) HK97-gp10_like PF04883.7 AET39009.1 - 0.037 14.9 0.8 1.4 9.8 0.1 3.3 4 0 0 4 4 4 0 Bacteriophage HK97-gp10, putative tail-component DNA_pol_B_thumb PF14791.1 AET39009.1 - 0.067 12.8 0.1 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase beta thumb DUF465 PF04325.8 AET39009.1 - 0.24 11.1 2.9 8 6.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Mid1 PF12929.2 AET39010.1 - 2.9e-129 431.5 12.0 3.6e-129 431.2 8.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 AET39010.1 - 0.024 14.9 3.0 1.2 9.5 0.2 2.7 3 0 0 3 3 3 0 Fz domain AAA PF00004.24 AET39011.1 - 1.5e-18 67.2 0.0 2.5e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 AET39011.1 - 6.9e-18 64.4 0.2 1.4e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AET39011.1 - 7.3e-17 61.5 0.0 9.9e-15 54.5 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 AET39011.1 - 7.3e-08 32.6 1.4 0.012 15.7 0.1 2.9 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 AET39011.1 - 2e-07 31.2 0.2 1.7e-06 28.1 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 AET39011.1 - 2.4e-07 29.8 0.0 1.3e-05 24.1 0.0 2.2 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 AET39011.1 - 1.1e-06 27.9 0.0 2.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AET39011.1 - 7.4e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 AET39011.1 - 3.5e-05 22.8 0.0 5.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 AET39011.1 - 8e-05 22.3 0.1 0.00045 19.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 AET39011.1 - 0.00015 21.4 0.1 0.0005 19.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AET39011.1 - 0.00017 21.1 0.6 0.28 10.5 0.0 2.7 2 1 1 3 3 3 2 AAA-like domain AAA_19 PF13245.1 AET39011.1 - 0.00019 21.1 0.0 0.00058 19.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 AET39011.1 - 0.00026 20.5 0.0 0.00058 19.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 AET39011.1 - 0.00054 19.4 0.1 0.011 15.2 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase DNA_pol3_delta PF06144.8 AET39011.1 - 0.00061 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.1 AET39011.1 - 0.00061 20.0 0.0 0.0016 18.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 AET39011.1 - 0.00068 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 AET39011.1 - 0.00074 20.3 0.0 0.0026 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AET39011.1 - 0.00095 18.8 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AET39011.1 - 0.0014 18.2 1.0 0.057 12.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 AET39011.1 - 0.0015 18.3 0.1 0.09 12.6 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 AET39011.1 - 0.0015 17.9 0.1 0.12 11.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AET39011.1 - 0.0021 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase Mg_chelatase PF01078.16 AET39011.1 - 0.0023 17.1 0.0 0.013 14.6 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI MobB PF03205.9 AET39011.1 - 0.0028 17.3 0.0 0.0097 15.6 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 AET39011.1 - 0.0042 16.3 0.1 1.8 7.7 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.13 AET39011.1 - 0.0065 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 AET39011.1 - 0.0067 16.3 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AET39011.1 - 0.0079 16.3 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DUF4442 PF14539.1 AET39011.1 - 0.015 15.2 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) AAA_33 PF13671.1 AET39011.1 - 0.016 15.0 0.3 0.039 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 AET39011.1 - 0.025 14.0 0.0 0.049 13.0 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 AET39011.1 - 0.042 12.6 0.1 3.3 6.4 0.0 2.5 2 1 1 3 3 3 0 ArgK protein DUF2075 PF09848.4 AET39011.1 - 0.048 12.6 0.0 0.15 11.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 AET39011.1 - 0.19 12.0 1.7 0.33 11.2 0.4 1.9 2 1 0 2 2 1 0 AAA domain Cyclin_N PF00134.18 AET39012.1 - 1.5e-17 63.3 0.0 2.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 AET39012.1 - 1.9e-11 44.6 0.0 2.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin UL40 PF10682.4 AET39013.1 - 0.035 13.6 0.1 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 Rcd1 PF04078.8 AET39014.1 - 1.1e-122 407.9 4.0 1.4e-122 407.6 2.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PAT1 PF09770.4 AET39014.1 - 0.26 9.5 16.4 0.37 8.9 11.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Adaptin_N PF01602.15 AET39015.1 - 2.5e-104 349.5 7.7 3.2e-104 349.1 5.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 AET39015.1 - 3.2e-47 160.1 2.2 7.9e-47 158.8 1.5 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 AET39015.1 - 1.2e-08 35.0 0.1 0.038 14.2 0.0 4.8 2 2 3 5 5 5 2 HEAT repeats HEAT PF02985.17 AET39015.1 - 0.00036 20.3 2.7 15 6.0 0.0 6.7 8 0 0 8 8 8 1 HEAT repeat DUF3355 PF11835.3 AET39015.1 - 0.0057 16.4 1.9 0.012 15.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3355) HEAT_EZ PF13513.1 AET39015.1 - 0.16 12.5 0.1 4.9 7.7 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat Ribosomal_L18e PF00828.14 AET39016.1 - 1.5e-22 80.3 0.3 2.8e-22 79.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 HLH PF00010.21 AET39017.1 - 0.00029 20.4 0.2 0.00058 19.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PLC-beta_C PF08703.5 AET39017.1 - 0.05 13.3 2.2 0.062 13.0 1.5 1.1 1 0 0 1 1 1 0 PLC-beta C terminal DUF3024 PF11225.3 AET39017.1 - 0.092 12.6 0.6 0.18 11.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) DUF1980 PF09323.5 AET39017.1 - 0.11 12.2 0.5 0.14 11.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF365 PF04033.7 AET39017.1 - 0.11 12.4 2.3 0.15 12.0 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) ADH_zinc_N PF00107.21 AET39018.1 - 3e-06 26.8 0.0 5.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AET39018.1 - 0.033 13.9 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF1257 PF06868.6 AET39018.1 - 0.11 12.4 0.5 1.7 8.5 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1257) Mannosyl_trans3 PF11051.3 AET39019.1 - 1.3e-57 195.2 0.0 1e-56 192.2 0.0 2.1 2 0 0 2 2 2 1 Mannosyltransferase putative MtN3_slv PF03083.11 AET39019.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Pkinase PF00069.20 AET39021.1 - 1.4e-61 207.8 0.0 2.4e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39021.1 - 1.8e-31 109.2 0.0 2.5e-30 105.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AET39021.1 - 0.0043 17.5 1.2 0.018 15.5 0.8 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AET39021.1 - 0.01 14.8 0.0 0.08 11.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like CTP_transf_1 PF01148.15 AET39022.1 - 2.8e-78 263.1 23.0 3.9e-78 262.6 15.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3449 PF11931.3 AET39023.1 - 8.2e-69 231.0 0.1 8.2e-69 231.0 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 AET39023.1 - 3.6e-05 23.7 10.6 0.0001 22.3 0.0 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AET39023.1 - 6.6e-05 22.9 6.5 0.00012 22.0 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AET39023.1 - 0.00094 19.2 2.8 0.057 13.5 0.1 3.1 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF3450 PF11932.3 AET39023.1 - 0.79 8.9 0.0 0.79 8.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) tRNA_Me_trans PF03054.11 AET39024.1 - 5.1e-116 387.1 0.0 5.8e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 AET39024.1 - 8.6e-05 22.1 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AET39024.1 - 0.0044 15.9 0.0 0.083 11.7 0.0 2.4 2 1 0 2 2 2 1 NAD synthase Inositol_P PF00459.20 AET39025.1 - 3.5e-49 167.5 0.0 8.5e-49 166.2 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Exo_endo_phos PF03372.18 AET39026.1 - 3.8e-15 56.4 0.1 4.8e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PseudoU_synth_2 PF00849.17 AET39027.1 - 2e-31 109.0 0.0 3.4e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 AET39027.1 - 2.8e-18 65.4 0.0 6.6e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region NARP1 PF12569.3 AET39028.1 - 1.3e-113 380.5 28.6 4.7e-79 266.4 5.5 3.0 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 AET39028.1 - 9.5e-16 58.0 5.0 0.0019 18.7 0.0 6.0 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 AET39028.1 - 4e-13 48.1 13.4 0.0002 21.0 0.1 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 AET39028.1 - 3e-12 46.0 0.1 0.0058 17.1 0.0 5.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 AET39028.1 - 1.1e-09 37.7 10.4 0.0014 18.2 0.0 5.7 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.23 AET39028.1 - 1.1e-09 37.4 7.9 0.0038 16.7 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 AET39028.1 - 3.1e-08 33.8 5.6 0.025 14.9 0.1 5.6 4 1 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 AET39028.1 - 9e-08 32.1 11.7 0.068 13.3 0.1 5.0 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 AET39028.1 - 2.1e-05 24.3 12.1 0.018 14.9 0.4 6.2 4 2 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 AET39028.1 - 0.00011 21.6 13.9 0.12 12.2 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 AET39028.1 - 0.00014 21.8 6.8 0.44 10.8 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 AET39028.1 - 0.0015 18.1 2.5 23 5.1 0.0 5.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AET39028.1 - 0.0045 17.3 12.2 0.25 11.8 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AET39028.1 - 0.016 15.0 8.6 0.25 11.2 0.2 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Arrestin_C PF02752.17 AET39029.1 - 2.6e-22 79.3 0.0 7.5e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AET39029.1 - 7.7e-11 42.0 0.0 2.6e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 AET39029.1 - 0.002 17.6 0.0 0.0085 15.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin_N terminal like Memo PF01875.12 AET39029.1 - 0.089 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Memo-like protein WD40 PF00400.27 AET39030.1 - 5.1e-09 35.6 0.0 0.0025 17.6 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF676 PF05057.9 AET39031.1 - 1.5e-41 142.0 0.1 2.3e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 AET39031.1 - 4.5e-05 23.1 0.1 8.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 AET39031.1 - 0.016 14.9 0.0 0.052 13.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 AET39031.1 - 0.049 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 AET39031.1 - 0.13 12.0 0.2 0.59 9.9 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sedlin_N PF04628.8 AET39032.1 - 4.3e-08 33.0 0.0 4.7e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_2 PF00890.19 AET39033.1 - 2.9e-72 243.8 0.0 3.4e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AET39033.1 - 6.3e-08 32.7 0.1 0.0072 16.2 0.1 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AET39033.1 - 6.5e-07 29.2 0.0 1.8e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AET39033.1 - 2.7e-06 26.5 0.1 2.5e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 AET39033.1 - 3.7e-06 26.2 0.9 0.00032 19.8 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 AET39033.1 - 5.7e-06 26.5 0.0 5.8e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AET39033.1 - 2.4e-05 23.0 0.6 0.022 13.2 0.1 3.2 2 1 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.14 AET39033.1 - 0.0015 17.6 0.3 0.0028 16.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 AET39033.1 - 0.0073 15.2 0.1 0.24 10.2 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 AET39033.1 - 0.024 13.7 0.0 0.04 12.9 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 AET39033.1 - 0.036 12.9 1.1 0.12 11.1 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A ATP-synt_F PF01990.12 AET39033.1 - 0.048 14.0 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Beta_elim_lyase PF01212.16 AET39034.1 - 9.2e-78 261.3 0.0 1.1e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase YL1_C PF08265.6 AET39035.1 - 9.9e-16 56.9 0.8 4e-15 55.0 0.1 2.1 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain fn3 PF00041.16 AET39036.1 - 0.0005 20.1 0.2 0.0022 18.0 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain RNase_HII PF01351.13 AET39036.1 - 0.045 13.3 3.4 0.12 12.0 2.1 1.9 1 1 0 1 1 1 0 Ribonuclease HII Syntaxin-6_N PF09177.6 AET39036.1 - 7.4 7.0 11.2 0.59 10.5 0.7 3.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Isy1 PF06246.7 AET39037.1 - 3.5e-58 196.9 18.1 1.6e-57 194.8 12.5 1.8 1 1 0 1 1 1 1 Isy1-like splicing family Snf7 PF03357.16 AET39037.1 - 0.061 12.7 3.3 4.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Snf7 Seryl_tRNA_N PF02403.17 AET39037.1 - 0.11 12.5 0.3 0.11 12.5 0.2 2.9 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 AET39037.1 - 0.12 11.8 5.0 0.99 8.9 0.6 2.9 3 0 0 3 3 3 0 Septum formation initiator GDA1_CD39 PF01150.12 AET39038.1 - 1e-102 343.8 0.0 1.3e-102 343.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family RNA_pol_Rpb1_4 PF05000.12 AET39038.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 DUF2278 PF10042.4 AET39038.1 - 0.049 13.3 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) CD52 PF15116.1 AET39038.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 CAMPATH-1 antigen NAD_kinase PF01513.16 AET39039.1 - 1.9e-75 253.2 0.0 2.8e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 AET39039.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Cytochrom_C PF00034.16 AET39040.1 - 4.1e-08 33.9 0.3 7.4e-08 33.1 0.2 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 AET39040.1 - 7.8e-07 29.1 3.7 7.3e-06 26.0 2.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 AET39040.1 - 0.0092 15.4 0.6 0.057 12.8 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain HAD_2 PF13419.1 AET39041.1 - 1e-22 81.2 0.0 1.3e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AET39041.1 - 0.00091 18.8 0.1 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like UBA PF00627.26 AET39042.1 - 1.4e-20 72.5 0.7 3.1e-13 49.1 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 AET39042.1 - 2.2e-13 49.3 0.6 4.2e-13 48.4 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 AET39042.1 - 6.9e-12 44.6 0.1 1.2e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 AET39042.1 - 2.3e-07 30.4 0.5 4.8e-07 29.3 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AET39042.1 - 2.4e-05 24.4 0.0 4.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 AET39042.1 - 0.00027 20.8 0.1 0.00054 19.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 AET39042.1 - 0.0061 16.0 1.3 4 7.0 0.0 3.9 3 2 1 4 4 4 1 CUE domain HEAT_2 PF13646.1 AET39042.1 - 0.045 14.0 0.0 0.44 10.8 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.17 AET39042.1 - 0.057 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat UBA_3 PF09288.5 AET39042.1 - 0.066 12.8 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF1421 PF07223.6 AET39042.1 - 0.19 11.5 5.3 0.055 13.2 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1421) DUF4126 PF13548.1 AET39042.1 - 3.5 7.0 6.5 29 4.0 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) Anp1 PF03452.9 AET39043.1 - 2.4e-121 404.0 0.0 3.4e-121 403.5 0.0 1.2 1 0 0 1 1 1 1 Anp1 eIF-5a PF01287.15 AET39044.1 - 4.4e-28 97.0 0.5 6.4e-28 96.4 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 AET39044.1 - 0.00027 20.5 0.5 0.00052 19.6 0.4 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 AET39044.1 - 0.0063 16.3 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain TcdB_toxin_midN PF12256.3 AET39044.1 - 0.031 13.7 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region MCM PF00493.18 AET39045.1 - 1.6e-127 424.8 0.1 2.3e-127 424.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AET39045.1 - 5.8e-20 71.9 0.0 1.4e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AET39045.1 - 3.3e-08 32.9 0.0 1.6e-06 27.4 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AET39045.1 - 0.0031 17.1 0.0 0.0067 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AET39045.1 - 0.0058 16.1 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain HAD PF12710.2 AET39046.1 - 8.4e-25 88.0 0.0 1.5e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AET39046.1 - 1.8e-24 87.3 0.0 1e-23 84.9 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AET39046.1 - 2.2e-17 62.8 0.1 4.5e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 AET39046.1 - 5.1e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AET39046.1 - 0.0032 17.0 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HupF_HypC PF01455.13 AET39047.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 HupF/HypC family HSP70 PF00012.15 AET39048.1 - 3.1e-263 874.1 15.7 3.6e-263 873.9 10.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AET39048.1 - 3.2e-16 58.8 5.7 1.3e-14 53.5 1.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 AET39048.1 - 0.0007 19.2 0.1 0.0023 17.6 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 AET39048.1 - 0.039 13.8 11.9 1.1 9.0 1.5 4.7 4 1 0 4 4 4 0 Cell division protein FtsA DUF2797 PF10977.3 AET39048.1 - 0.093 12.3 3.1 0.21 11.2 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Hydantoinase_A PF01968.13 AET39048.1 - 0.37 9.8 9.1 0.33 10.0 0.1 3.6 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase Vps55 PF04133.9 AET39049.1 - 5.4e-40 135.8 2.5 6.4e-40 135.6 1.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2085 PF09858.4 AET39049.1 - 0.035 14.1 1.0 0.043 13.9 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) DUF3671 PF12420.3 AET39049.1 - 0.042 13.8 0.8 0.068 13.1 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF2108 PF09881.4 AET39049.1 - 0.3 10.9 4.4 0.36 10.6 0.1 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2108) WD40 PF00400.27 AET39050.1 - 0.0012 18.6 2.1 4.5 7.3 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat PID PF00640.18 AET39050.1 - 0.03 14.2 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Sld5 PF05916.6 AET39051.1 - 2.6e-14 53.4 1.8 6.2e-14 52.1 1.2 1.7 1 0 0 1 1 1 1 GINS complex protein Peptidase_M16_C PF05193.16 AET39052.1 - 7.5e-21 74.6 0.0 6.9e-17 61.7 0.0 3.9 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AET39052.1 - 3.3e-06 26.9 0.0 8.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) UPF0180 PF03698.8 AET39052.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) PcrB PF01884.12 AET39052.1 - 0.065 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 PcrB family RQC PF09382.5 AET39052.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 RQC domain Pkinase PF00069.20 AET39053.1 - 1.8e-63 214.1 0.0 3.2e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39053.1 - 7.5e-34 116.9 0.0 1.3e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET39053.1 - 5e-10 38.8 0.0 7.8e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AET39053.1 - 0.00013 21.1 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M35 PF02102.10 AET39053.1 - 0.016 13.8 3.8 0.026 13.2 2.7 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family APH PF01636.18 AET39053.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HlyIII PF03006.15 AET39055.1 - 3.8e-51 173.6 24.2 4.5e-51 173.3 16.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.3 AET39055.1 - 1.7 8.5 4.1 4.3 7.2 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) DUF2583 PF10762.4 AET39055.1 - 3.3 7.9 7.2 0.52 10.4 0.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) PTS_2-RNA PF01885.11 AET39056.1 - 3e-57 192.9 0.3 4e-57 192.5 0.2 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PARP PF00644.15 AET39056.1 - 0.0079 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain CPL PF08144.6 AET39059.1 - 4.4e-16 59.0 4.9 1.1e-14 54.4 0.0 4.0 4 0 0 4 4 4 2 CPL (NUC119) domain PUF PF00806.14 AET39059.1 - 6.4e-07 28.5 2.4 0.35 10.4 0.0 5.9 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat Sec20 PF03908.8 AET39060.1 - 3.2e-23 81.2 1.9 3.2e-23 81.2 1.3 2.5 2 0 0 2 2 2 1 Sec20 V-SNARE_C PF12352.3 AET39060.1 - 0.0018 18.3 10.4 0.13 12.3 0.1 3.5 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Glycogen_syn PF05693.8 AET39060.1 - 0.081 11.1 0.2 0.11 10.7 0.2 1.1 1 0 0 1 1 1 0 Glycogen synthase NPV_P10 PF05531.7 AET39060.1 - 1.1 9.6 5.2 0.77 10.0 0.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Peroxidase_2 PF01328.12 AET39060.1 - 6.4 5.3 7.4 0.24 10.0 0.1 2.1 2 1 1 3 3 3 0 Peroxidase, family 2 SRI PF08236.6 AET39061.1 - 0.0054 16.6 1.7 1.8 8.5 0.1 2.5 2 0 0 2 2 2 2 SRI (Set2 Rpb1 interacting) domain ERG4_ERG24 PF01222.12 AET39062.1 - 4.5e-162 539.4 17.2 5.1e-162 539.2 11.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 AET39062.1 - 0.00036 19.9 0.6 0.00091 18.5 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PPTA PF01239.17 AET39062.1 - 0.09 12.1 1.5 2.7 7.5 0.0 2.8 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Aha1_N PF09229.6 AET39063.1 - 2.6e-31 108.2 0.5 3.1e-31 108.0 0.4 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.6 AET39064.1 - 2.4e-43 147.6 0.0 2.9e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.14 AET39065.1 - 8e-11 41.7 11.1 8e-11 41.7 7.7 3.0 3 1 0 3 3 3 1 WSC domain PepSY_TM_3 PF13706.1 AET39065.1 - 0.14 11.6 1.8 0.23 10.8 1.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix Syndecan PF01034.15 AET39065.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.6 AET39065.1 - 2.9 7.4 27.6 75 2.8 19.1 2.4 1 1 0 1 1 1 0 Podoplanin DUF3328 PF11807.3 AET39065.1 - 9.5 5.8 9.9 3.3 7.3 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3328) Transp_cyt_pur PF02133.10 AET39066.1 - 7.2e-152 505.9 36.3 8.4e-152 505.7 25.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ABC2_membrane PF01061.19 AET39067.1 - 1.1e-65 220.7 47.8 2.8e-38 131.2 12.2 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 AET39067.1 - 1.3e-40 138.8 0.0 2.1e-19 70.1 0.0 3.1 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 AET39067.1 - 3.9e-38 129.2 3.0 4.2e-33 113.0 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 AET39067.1 - 9.8e-09 35.1 0.0 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 AET39067.1 - 4.8e-08 32.4 44.4 7.8e-08 31.7 10.9 3.3 2 2 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 AET39067.1 - 1.1e-06 27.9 0.1 0.00029 20.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 AET39067.1 - 2.5e-05 23.7 0.0 0.0048 16.3 0.0 3.1 4 0 0 4 4 4 1 AAA domain Miro PF08477.8 AET39067.1 - 3.2e-05 24.3 0.0 0.39 11.2 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 AET39067.1 - 0.0003 20.8 1.1 0.15 11.9 0.1 3.2 3 1 0 3 3 3 1 AAA ATPase domain cobW PF02492.14 AET39067.1 - 0.00035 20.0 0.6 0.0013 18.2 0.1 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 AET39067.1 - 0.00036 20.6 0.0 0.025 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AET39067.1 - 0.00087 18.7 0.1 0.066 12.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 AET39067.1 - 0.0017 17.6 0.0 0.099 11.8 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 AET39067.1 - 0.0037 17.1 0.0 0.32 10.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AET39067.1 - 0.0072 16.1 1.2 0.046 13.5 0.0 2.6 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.13 AET39067.1 - 0.012 15.0 0.1 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 AET39067.1 - 0.013 15.1 0.3 0.33 10.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 AET39067.1 - 0.023 15.0 0.0 0.17 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 AET39067.1 - 0.033 14.1 5.0 0.52 10.2 0.0 3.9 4 1 0 4 4 3 0 AAA domain Septin PF00735.13 AET39067.1 - 0.033 13.1 1.5 0.15 11.0 0.0 2.3 2 0 0 2 2 2 0 Septin NACHT PF05729.7 AET39067.1 - 0.046 13.3 0.6 0.39 10.3 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 AET39067.1 - 0.052 14.3 0.9 0.21 12.4 0.0 2.5 3 0 0 3 3 1 0 AAA domain Zeta_toxin PF06414.7 AET39067.1 - 0.069 12.2 0.0 8.7 5.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 AET39067.1 - 0.084 12.4 0.9 2 7.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AET39067.1 - 0.094 12.6 0.7 0.19 11.6 0.1 1.8 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 AET39067.1 - 0.094 12.1 0.1 0.72 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 AET39067.1 - 0.13 12.1 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AET39067.1 - 0.16 12.1 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 AET39067.1 - 0.22 10.0 0.2 0.38 9.2 0.2 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_23 PF13476.1 AET39067.1 - 0.81 9.9 6.5 1.4 9.2 0.2 2.6 3 0 0 3 3 2 0 AAA domain ABC2_membrane PF01061.19 AET39068.1 - 4.4e-86 287.3 63.4 4.7e-48 163.1 15.6 3.0 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 AET39068.1 - 2.7e-36 123.3 10.5 4.8e-35 119.3 0.1 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 AET39068.1 - 1.2e-29 103.3 0.0 6.7e-16 58.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 AET39068.1 - 3.9e-19 68.5 0.0 1.1e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 AET39068.1 - 1.9e-05 23.9 0.0 0.0034 16.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 AET39068.1 - 2.2e-05 23.9 0.0 0.0012 18.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.2 AET39068.1 - 3.4e-05 23.0 56.9 8.3e-05 21.7 15.6 4.0 2 2 2 4 4 3 2 ABC-2 family transporter protein AAA_16 PF13191.1 AET39068.1 - 7.2e-05 22.8 0.2 0.0088 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AET39068.1 - 0.00027 21.0 0.0 0.036 14.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 AET39068.1 - 0.00039 21.2 0.0 0.068 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AET39068.1 - 0.00051 20.0 0.1 0.062 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AET39068.1 - 0.00057 19.5 0.1 0.86 9.3 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain cobW PF02492.14 AET39068.1 - 0.00071 19.0 0.2 0.005 16.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 AET39068.1 - 0.0058 16.1 0.2 0.043 13.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 AET39068.1 - 0.053 13.8 0.0 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AET39068.1 - 0.056 13.3 0.1 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AET39068.1 - 0.067 12.8 0.4 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Miro PF08477.8 AET39068.1 - 0.072 13.5 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein SMC_N PF02463.14 AET39068.1 - 0.12 11.5 0.0 2 7.6 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 AET39068.1 - 0.14 12.0 0.0 9.1 6.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 AET39068.1 - 0.27 11.4 0.1 9.5 6.4 0.1 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 AET39068.1 - 0.33 10.5 0.2 13 5.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Chitin_synth_2 PF03142.10 AET39069.1 - 8.5e-276 915.4 0.2 1.2e-275 914.8 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 AET39069.1 - 2.1e-17 63.4 0.5 8.3e-17 61.5 0.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AET39069.1 - 5.6e-14 52.4 0.0 1.9e-12 47.4 0.0 2.4 1 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AET39069.1 - 0.0001 21.6 0.0 0.0004 19.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 AET39069.1 - 0.00013 21.6 0.0 0.0045 16.6 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cyt-b5 PF00173.23 AET39069.1 - 0.00017 21.3 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain fn3_3 PF14686.1 AET39069.1 - 0.014 15.4 0.0 0.081 13.0 0.1 2.1 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II SCO1-SenC PF02630.9 AET39070.1 - 2.6e-67 225.7 0.0 3.4e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 AET39070.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family YchF-GTPase_C PF06071.8 AET39071.1 - 9.7e-37 124.6 0.5 2.2e-36 123.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 AET39071.1 - 4.2e-13 49.2 0.0 1.7e-12 47.3 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 AET39071.1 - 0.00068 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 AET39071.1 - 0.007 15.6 0.0 0.018 14.3 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Dna2 PF08696.6 AET39071.1 - 0.023 13.9 0.2 0.046 13.0 0.1 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF3236 PF11576.3 AET39071.1 - 0.079 12.3 1.2 0.16 11.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) SecA_PP_bind PF01043.15 AET39071.1 - 0.08 13.3 0.9 0.96 9.8 0.0 2.3 2 0 0 2 2 2 0 SecA preprotein cross-linking domain AAA_18 PF13238.1 AET39071.1 - 0.15 12.3 3.4 1.4 9.2 0.8 2.7 3 0 0 3 3 3 0 AAA domain PEMT PF04191.8 AET39072.1 - 1.1e-30 105.7 3.7 1.1e-30 105.7 2.6 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase ABC_membrane PF00664.18 AET39073.1 - 1.2e-79 267.6 27.7 3.9e-40 138.0 8.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AET39073.1 - 9.1e-59 197.6 1.8 2e-28 99.4 0.0 3.2 4 0 0 4 4 3 2 ABC transporter SMC_N PF02463.14 AET39073.1 - 1.5e-15 57.0 5.1 7.7e-06 25.2 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AET39073.1 - 1.2e-10 41.9 11.2 0.0029 17.6 0.1 5.8 3 2 2 5 5 5 3 AAA domain ABC_ATPase PF09818.4 AET39073.1 - 2.2e-09 36.4 0.2 0.0038 15.8 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 AET39073.1 - 3.2e-09 36.1 0.5 0.00093 18.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 AET39073.1 - 1.4e-06 28.4 3.4 0.0044 17.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_10 PF12846.2 AET39073.1 - 3.2e-06 26.8 4.9 0.004 16.6 0.5 3.4 2 2 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 AET39073.1 - 5.3e-06 25.7 0.0 0.0034 16.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AET39073.1 - 8.6e-06 26.5 1.0 0.012 16.4 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AET39073.1 - 2.2e-05 24.9 0.3 0.11 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AET39073.1 - 2.2e-05 24.5 0.7 0.043 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain CbiA PF01656.18 AET39073.1 - 2.7e-05 23.6 0.1 0.054 12.8 0.0 2.4 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.12 AET39073.1 - 9.4e-05 21.8 0.7 6.2 6.1 0.0 4.8 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_18 PF13238.1 AET39073.1 - 0.00012 22.3 2.5 0.021 15.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 AET39073.1 - 0.00014 21.7 2.7 0.093 12.5 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_13 PF13166.1 AET39073.1 - 0.00022 19.8 1.9 0.026 13.0 0.1 2.9 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 AET39073.1 - 0.00056 19.4 0.0 0.53 9.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 AET39073.1 - 0.001 18.9 1.2 0.053 13.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 AET39073.1 - 0.0011 18.6 0.1 0.53 10.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 AET39073.1 - 0.002 17.0 0.0 1.1 8.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 AET39073.1 - 0.0025 17.5 1.0 0.45 10.2 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AET39073.1 - 0.0028 17.5 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AET39073.1 - 0.0031 16.9 0.0 1.9 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.1 AET39073.1 - 0.0048 15.5 0.0 0.21 10.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) RNA_helicase PF00910.17 AET39073.1 - 0.0048 17.0 0.1 0.48 10.6 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 AET39073.1 - 0.016 14.3 0.0 0.16 11.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 AET39073.1 - 0.047 13.2 0.0 7.2 6.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 AET39073.1 - 0.052 13.1 1.2 7.7 6.1 0.0 3.3 3 0 0 3 3 3 0 NACHT domain AAA_15 PF13175.1 AET39073.1 - 0.059 12.4 0.5 6.9 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 AET39073.1 - 0.082 12.8 0.1 1.1 9.1 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ThiF PF00899.16 AET39074.1 - 4.7e-49 165.6 0.2 1.1e-30 106.1 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 AET39074.1 - 3.1e-44 150.1 0.4 1.6e-43 147.8 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 AET39074.1 - 8.6e-30 102.1 0.0 3.8e-23 80.8 0.0 2.9 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AET39074.1 - 2.7e-26 90.6 0.6 8.6e-20 69.8 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Mog1 PF04603.7 AET39075.1 - 2.9e-17 62.9 0.4 4.6e-16 59.0 0.3 2.5 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Gly_transf_sug PF04488.10 AET39076.1 - 9.7e-11 41.9 0.9 3.4e-10 40.2 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Myosin_tail_1 PF01576.14 AET39076.1 - 0.012 13.3 4.3 0.017 12.8 3.0 1.1 1 0 0 1 1 1 0 Myosin tail IMD PF08397.6 AET39076.1 - 0.021 14.1 1.9 0.036 13.3 1.3 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain TMEM192 PF14802.1 AET39076.1 - 0.055 12.3 1.3 0.081 11.7 0.9 1.2 1 0 0 1 1 1 0 TMEM192 family IncA PF04156.9 AET39076.1 - 0.092 12.3 3.5 0.15 11.6 2.4 1.3 1 0 0 1 1 1 0 IncA protein DDE_Tnp_1_2 PF13586.1 AET39076.1 - 0.14 12.3 0.2 0.34 11.1 0.2 1.6 1 0 0 1 1 1 0 Transposase DDE domain Septin PF00735.13 AET39077.1 - 1e-108 362.6 0.0 1e-108 362.6 0.0 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 AET39077.1 - 1.5e-07 31.3 0.0 3.3e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AET39077.1 - 9.9e-06 25.4 9.2 0.0025 17.6 0.2 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 AET39077.1 - 7.4e-05 21.9 1.0 0.00045 19.4 0.7 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 AET39077.1 - 0.00018 21.8 1.4 0.0003 21.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 AET39077.1 - 0.00022 20.4 0.1 0.00022 20.4 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 AET39077.1 - 0.0013 19.2 0.8 0.0043 17.5 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein IIGP PF05049.8 AET39077.1 - 0.0015 17.4 0.1 0.0032 16.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.2 AET39077.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 AET39077.1 - 0.051 13.2 0.2 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 AET39077.1 - 0.078 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 AET39077.1 - 0.084 12.3 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 AET39077.1 - 0.092 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 AET39077.1 - 0.12 11.8 1.6 1.5 8.2 0.1 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 AET39077.1 - 0.18 11.2 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 AET39077.1 - 0.33 11.2 7.7 0.21 11.8 1.9 2.4 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 AET39077.1 - 0.37 9.4 6.5 0.25 9.9 0.1 2.9 3 0 0 3 3 3 0 G-protein alpha subunit IGPS PF00218.16 AET39078.1 - 2.9e-88 295.2 0.0 3.7e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 AET39078.1 - 8e-52 175.4 0.0 1.2e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AET39078.1 - 1.3e-06 28.0 0.0 2.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 AET39078.1 - 0.017 14.6 0.0 0.13 11.7 0.1 2.1 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Repressor_Mnt PF11423.3 AET39078.1 - 0.13 11.5 0.2 0.13 11.5 0.1 2.0 2 0 0 2 2 2 0 Regulatory protein Mnt Rho_N PF07498.7 AET39078.1 - 0.26 11.0 1.8 0.77 9.5 0.2 2.2 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Syja_N PF02383.13 AET39079.1 - 4.6e-85 285.2 2.5 5.8e-85 284.8 1.7 1.1 1 0 0 1 1 1 1 SacI homology domain PUL PF08324.6 AET39080.1 - 1.3e-55 188.0 0.4 2e-55 187.4 0.3 1.3 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 AET39080.1 - 8e-44 146.0 9.3 4.7e-09 35.7 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat PFU PF09070.6 AET39080.1 - 3.1e-42 143.2 0.1 7.1e-42 142.0 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.1 AET39080.1 - 0.0006 19.5 0.1 2.4 7.9 0.0 3.5 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region FoP_duplication PF13865.1 AET39081.1 - 2.2e-06 27.9 3.7 3e-06 27.5 2.2 1.6 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_6 PF14259.1 AET39081.1 - 0.0012 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET39081.1 - 0.037 13.6 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 AET39082.1 - 1.5e-49 165.6 7.2 4.4e-20 71.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.7 AET39082.1 - 0.074 12.7 0.1 7.7 6.3 0.0 2.8 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family NMT1 PF09084.6 AET39083.1 - 2.2e-76 256.2 0.0 2.7e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 AET39083.1 - 3.3e-06 26.6 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 2 NMT1-like family PBP_like PF12727.2 AET39083.1 - 0.027 13.4 0.0 0.082 11.8 0.0 1.7 1 1 0 1 1 1 0 PBP superfamily domain Phosphonate-bd PF12974.2 AET39083.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Integrase_AP2 PF14657.1 AET39084.1 - 0.0079 15.9 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 AP2-like DNA-binding integrase domain RTA1 PF04479.8 AET39085.1 - 7.2e-64 215.3 14.6 7.2e-64 215.3 10.1 1.4 2 0 0 2 2 2 1 RTA1 like protein Caveolin PF01146.12 AET39085.1 - 0.025 14.1 0.3 0.025 14.1 0.2 1.8 2 0 0 2 2 2 0 Caveolin Syndecan PF01034.15 AET39085.1 - 1.9 8.2 4.0 1.3 8.7 0.3 2.5 2 0 0 2 2 2 0 Syndecan domain Thiolase_N PF00108.18 AET39087.1 - 1.9e-86 289.3 0.2 2.6e-86 288.8 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AET39087.1 - 1.8e-46 156.5 0.5 3.2e-46 155.7 0.3 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 AET39087.1 - 0.00025 20.6 0.2 0.00068 19.1 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 AET39087.1 - 0.042 13.5 4.7 1.1 9.0 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FH2 PF02181.18 AET39088.1 - 2.5e-66 224.0 8.9 2.5e-66 224.0 6.2 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 AET39088.1 - 9.1e-08 31.6 0.0 9.1e-08 31.6 0.0 3.1 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 AET39088.1 - 1.6e-05 24.4 2.2 1.6e-05 24.4 1.5 4.1 4 1 0 4 4 4 1 Diaphanous FH3 Domain BEX PF04538.7 AET39088.1 - 4.6 7.5 10.9 1.3 9.2 1.2 2.7 2 0 0 2 2 2 0 Brain expressed X-linked like family DUF1049 PF06305.6 AET39089.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) SKG6 PF08693.5 AET39089.1 - 0.14 11.4 0.5 0.32 10.3 0.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Coa1 PF08695.5 AET39090.1 - 1.2e-35 121.5 0.1 1.5e-35 121.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1748 PF08520.5 AET39091.1 - 1.4e-29 101.5 0.2 1.5e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Myb_DNA-bind_6 PF13921.1 AET39092.1 - 1e-27 96.0 3.4 6.8e-11 42.1 0.1 3.8 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AET39092.1 - 2.4e-22 78.7 8.6 4.7e-10 39.3 0.2 4.0 3 1 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 AET39092.1 - 0.048 13.5 4.9 2.8 7.9 0.1 3.7 2 1 1 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UCH PF00443.24 AET39093.1 - 1.3e-55 188.4 5.5 1.3e-55 188.4 3.8 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AET39093.1 - 2.6e-26 92.7 3.4 2.6e-26 92.7 2.3 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 AET39093.1 - 0.0011 19.3 0.0 0.0031 17.8 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain DAO PF01266.19 AET39094.1 - 1.5e-48 165.5 0.0 2.1e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AET39094.1 - 4.8e-13 48.7 1.0 1.5e-12 47.1 0.7 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AET39094.1 - 5.3e-10 38.9 0.1 9.3e-07 28.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 AET39094.1 - 3.1e-06 26.2 0.3 0.00086 18.2 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 AET39094.1 - 2.1e-05 23.7 0.1 0.027 13.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 AET39094.1 - 2.5e-05 24.2 0.3 0.0012 18.7 0.2 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AET39094.1 - 0.0004 20.3 0.3 0.00095 19.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AET39094.1 - 0.00047 18.7 0.2 0.00076 18.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 AET39094.1 - 0.00098 18.2 0.0 0.9 8.5 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.13 AET39094.1 - 0.027 14.1 0.8 0.12 11.9 0.6 2.1 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 AET39094.1 - 0.08 13.3 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PTPA PF03095.10 AET39096.1 - 1e-103 346.6 0.0 1.2e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PEPCK_ATP PF01293.15 AET39097.1 - 3.2e-217 721.6 0.0 3.9e-217 721.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 AET39097.1 - 0.0057 16.5 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AET39097.1 - 0.0071 15.8 0.1 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 AET39097.1 - 0.034 13.5 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 AET39097.1 - 0.061 12.4 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC PIN_4 PF13638.1 AET39099.1 - 1.1e-11 45.0 0.2 3.6e-11 43.2 0.1 2.0 1 0 0 1 1 1 1 PIN domain Pcc1 PF09341.5 AET39100.1 - 8.2e-19 67.4 0.0 1.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Transcription factor Pcc1 TPR_MLP1_2 PF07926.7 AET39101.1 - 3.4e-27 94.7 26.3 3.4e-27 94.7 18.2 16.4 5 3 6 14 14 14 8 TPR/MLP1/MLP2-like protein ubiquitin PF00240.18 AET39102.1 - 6.3e-35 118.4 0.7 8.2e-35 118.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 AET39102.1 - 3.3e-31 106.6 10.9 5.2e-31 106.0 7.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 AET39102.1 - 6e-20 70.7 0.7 8.8e-20 70.1 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AET39102.1 - 8.2e-06 25.9 0.1 3e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AET39102.1 - 0.00017 21.2 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AET39102.1 - 0.0055 16.5 0.1 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AET39102.1 - 0.015 15.4 0.1 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 AET39102.1 - 0.19 11.5 1.6 0.79 9.5 1.1 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Response_reg PF00072.19 AET39103.1 - 1.8e-27 95.5 0.2 3.3e-27 94.7 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 AET39103.1 - 2e-27 95.0 1.1 8e-27 93.1 0.8 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AET39103.1 - 9.8e-12 44.7 0.2 2.8e-11 43.2 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 AET39103.1 - 4.5e-05 23.5 4.9 0.03 14.4 0.2 3.0 3 0 0 3 3 3 2 HAMP domain Syndecan PF01034.15 AET39103.1 - 0.23 11.1 0.8 0.56 9.9 0.6 1.6 1 0 0 1 1 1 0 Syndecan domain DMAP_binding PF06464.6 AET39104.1 - 0.07 13.7 0.3 0.15 12.6 0.2 1.5 1 0 0 1 1 1 0 DMAP1-binding Domain RE_HaeII PF09554.5 AET39104.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 HaeII restriction endonuclease TFIIE-A_C-term PF11521.3 AET39104.1 - 0.66 9.9 4.4 2.5 8.0 3.0 2.0 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Pantoate_ligase PF02569.10 AET39106.1 - 5.4e-94 314.0 0.1 6.1e-94 313.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Myosin_TH1 PF06017.8 AET39106.1 - 0.033 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Myosin tail FAD_syn PF06574.7 AET39106.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Ndc80_HEC PF03801.8 AET39107.1 - 5e-55 185.2 0.5 5e-55 185.2 0.3 2.0 2 0 0 2 2 2 1 HEC/Ndc80p family Spc7 PF08317.6 AET39107.1 - 0.083 11.5 46.9 0.0062 15.2 14.2 3.0 3 1 1 4 4 4 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 AET39107.1 - 1.3 8.8 50.2 0.17 11.7 4.6 4.6 2 2 0 3 3 3 0 Tropomyosin like ApoO PF09769.4 AET39107.1 - 3.7 7.2 8.2 3.5 7.3 1.7 2.9 2 1 0 2 2 2 0 Apolipoprotein O Helicase_C_3 PF13625.1 AET39108.1 - 2.2e-25 88.9 0.1 6.8e-25 87.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET39108.1 - 1.3e-13 51.2 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AET39108.1 - 7.2e-12 44.7 0.1 1.1e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AET39108.1 - 1.4e-10 40.8 0.0 3.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AET39108.1 - 7.7e-07 28.7 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 AET39108.1 - 0.017 14.4 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein SRP40_C PF05022.7 AET39109.1 - 2.3e-30 104.9 5.0 5.2e-30 103.7 3.5 1.6 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF605 PF04652.11 AET39109.1 - 1.5 8.0 42.3 2 7.7 29.3 1.2 1 0 0 1 1 1 0 Vta1 like Abhydrolase_6 PF12697.2 AET39110.1 - 5.6e-24 85.2 0.0 7.5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AET39110.1 - 5.1e-08 32.7 0.0 1.4e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET39110.1 - 3.3e-07 30.0 0.0 9.1e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 AET39110.1 - 2.9e-06 26.9 0.0 4.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 AET39110.1 - 0.026 13.7 0.1 0.073 12.2 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 AET39110.1 - 0.071 12.7 1.3 3.7 7.1 0.2 2.6 1 1 1 2 2 2 0 Lipase (class 3) LIM PF00412.17 AET39111.1 - 1.7e-16 59.9 26.1 1.4e-09 37.8 6.1 2.3 2 0 0 2 2 2 2 LIM domain DUF3336 PF11815.3 AET39112.1 - 3.7e-41 140.0 6.4 8.5e-41 138.8 4.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AET39112.1 - 6.2e-29 101.3 0.0 1.1e-28 100.6 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4506 PF14958.1 AET39112.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) TPR_11 PF13414.1 AET39113.1 - 2e-06 27.3 4.9 2.1e-05 24.0 0.2 2.9 2 1 0 2 2 2 1 TPR repeat F-box PF00646.28 AET39113.1 - 1.4e-05 24.6 2.5 5e-05 22.8 1.7 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AET39113.1 - 0.00038 20.1 1.1 0.00038 20.1 0.7 2.5 3 0 0 3 3 3 1 F-box-like TPR_12 PF13424.1 AET39113.1 - 0.0015 18.4 2.6 0.047 13.6 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat LRR_7 PF13504.1 AET39113.1 - 0.0034 17.3 0.9 21 5.8 0.1 5.4 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 AET39113.1 - 0.0076 15.8 8.7 3 7.5 0.3 4.9 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) TPR_2 PF07719.12 AET39113.1 - 0.0077 16.0 11.0 0.12 12.3 0.4 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 AET39113.1 - 0.039 13.5 0.2 0.039 13.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_6 PF13516.1 AET39113.1 - 0.4 10.8 3.2 14 6.0 0.2 4.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 AET39113.1 - 0.63 10.2 7.1 25 5.4 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat U3_snoRNA_assoc PF08297.6 AET39114.1 - 6.8e-19 67.8 7.8 6.8e-19 67.8 5.4 2.9 2 1 0 2 2 2 1 U3 snoRNA associated SNARE_assoc PF09335.6 AET39116.1 - 7.4e-14 52.0 9.2 7.4e-14 52.0 6.4 2.5 3 1 0 3 3 3 1 SNARE associated Golgi protein DUF4191 PF13829.1 AET39116.1 - 0.059 12.4 0.3 0.15 11.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FUSC PF04632.7 AET39116.1 - 0.066 11.6 0.2 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2207 PF09972.4 AET39116.1 - 0.52 8.8 4.8 0.2 10.2 1.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Kin17_mid PF10357.4 AET39117.1 - 1.2e-39 134.8 6.5 1.9e-39 134.1 4.5 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 AET39117.1 - 4.5e-07 29.8 3.0 1.3e-06 28.3 2.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AET39117.1 - 3e-05 24.0 2.9 7.4e-05 22.8 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AET39117.1 - 0.0024 17.9 1.2 0.0024 17.9 0.8 2.4 1 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) TFIID_90kDa PF04494.10 AET39117.1 - 0.0031 17.5 0.6 0.0064 16.5 0.4 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Prenyltrans PF00432.16 AET39117.1 - 0.085 12.4 0.1 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat zf-C2H2 PF00096.21 AET39117.1 - 0.29 11.5 2.7 0.72 10.3 1.9 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type AKAP95 PF04988.7 AET39117.1 - 0.33 10.7 8.5 0.073 12.8 3.5 1.7 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Peptidase_M48 PF01435.13 AET39118.1 - 5.1e-31 107.9 0.0 7.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 HA2 PF04408.18 AET39119.1 - 2.9e-24 85.0 0.4 1e-23 83.2 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AET39119.1 - 2e-22 79.1 0.0 5.2e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AET39119.1 - 3.1e-15 55.8 0.0 8.7e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AET39119.1 - 9.1e-06 25.8 0.1 2.9e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 AET39119.1 - 9.3e-06 25.2 0.1 2.5e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 AET39119.1 - 0.0093 14.8 0.1 0.023 13.6 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 AET39119.1 - 0.0097 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain Peptidase_M17_N PF02789.12 AET39119.1 - 0.017 14.8 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain AAA_30 PF13604.1 AET39119.1 - 0.028 13.9 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AET39119.1 - 0.032 13.7 0.1 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 AET39119.1 - 0.032 14.5 0.3 0.032 14.5 0.2 4.0 4 2 0 4 4 3 0 AAA domain AAA_14 PF13173.1 AET39119.1 - 0.24 11.2 5.5 0.2 11.5 0.7 2.8 2 1 0 2 2 2 0 AAA domain MRP-L20 PF12824.2 AET39120.1 - 2e-48 164.4 4.1 2.4e-48 164.2 2.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 AET39120.1 - 0.079 12.7 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Neugrin Syntaxin-18_N PF10496.4 AET39122.1 - 1.1e-14 53.9 1.0 2.8e-14 52.6 0.0 2.2 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 AET39122.1 - 0.0025 17.4 7.3 0.0025 17.4 5.0 2.5 3 0 0 3 3 3 1 SNARE domain DUF763 PF05559.6 AET39122.1 - 0.097 11.5 3.2 0.21 10.5 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF3708 PF12501.3 AET39122.1 - 0.13 12.0 1.9 0.32 10.8 1.0 1.8 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter NinG PF05766.7 AET39122.1 - 0.28 10.8 2.3 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein DUF919 PF06034.6 AET39122.1 - 0.33 10.5 10.8 1.5 8.5 1.4 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF3782 PF12644.2 AET39122.1 - 1 9.1 4.0 0.83 9.4 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) DUF1104 PF06518.6 AET39122.1 - 1.4 9.0 10.1 1.7 8.8 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) DUF948 PF06103.6 AET39122.1 - 2.1 8.2 16.3 3.1 7.7 3.0 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 AET39122.1 - 4.3 6.2 21.5 0.099 11.6 8.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Thymidylat_synt PF00303.14 AET39123.1 - 2.1e-118 394.2 0.0 2.4e-118 394.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Shugoshin_N PF07558.6 AET39124.1 - 2.1e-15 56.1 4.1 2.1e-15 56.1 2.8 2.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 AET39124.1 - 2.6e-11 42.7 5.2 2.6e-11 42.7 3.6 2.0 2 0 0 2 2 2 1 Shugoshin C terminus DASH_Dad2 PF08654.5 AET39125.1 - 3.1e-35 120.2 1.0 3.4e-35 120.1 0.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 FlaC_arch PF05377.6 AET39125.1 - 0.033 14.0 0.2 0.055 13.3 0.1 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) NuiA PF07924.6 AET39125.1 - 0.035 14.0 0.4 4.7 7.1 0.1 2.1 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein DUF3508 PF12018.3 AET39125.1 - 0.038 12.9 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) DASH_Duo1 PF08651.5 AET39125.1 - 0.042 13.4 0.8 0.062 12.8 0.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 Baculo_PEP_C PF04513.7 AET39125.1 - 0.061 13.1 0.3 0.065 13.0 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nucleoporin_C PF03177.9 AET39126.1 - 2.2e-61 208.1 17.4 2.2e-61 208.1 12.1 1.6 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 AET39126.1 - 1.2e-56 192.2 0.5 2e-56 191.5 0.4 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Brix PF04427.13 AET39127.1 - 2.6e-37 128.3 1.1 3.5e-37 127.9 0.7 1.2 1 0 0 1 1 1 1 Brix domain THF_DHG_CYH PF00763.18 AET39128.1 - 8.6e-19 67.6 0.0 1.6e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 AET39128.1 - 1.9e-17 62.7 0.0 3e-11 42.6 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RTP PF02334.11 AET39128.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Replication terminator protein RabGAP-TBC PF00566.13 AET39129.1 - 7.2e-51 172.6 2.1 1.3e-50 171.8 1.5 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lactamase_B_2 PF12706.2 AET39130.1 - 1.7e-35 122.3 0.0 3.4e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 AET39130.1 - 1.1e-23 82.4 0.0 2.3e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 AET39130.1 - 0.0084 15.7 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Vps5 PF09325.5 AET39131.1 - 1e-76 257.3 10.7 1e-76 257.3 7.4 2.0 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 AET39131.1 - 1.1e-24 86.3 3.3 1.4e-24 86.0 0.7 2.5 2 0 0 2 2 2 1 PX domain SQS_PSY PF00494.14 AET39131.1 - 0.048 12.9 0.2 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 Squalene/phytoene synthase DUF1664 PF07889.7 AET39131.1 - 1.8 8.3 8.6 14 5.5 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Alg6_Alg8 PF03155.10 AET39132.1 - 1.6e-144 482.2 43.1 1.9e-144 482.0 29.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Cytochrom_C1 PF02167.10 AET39134.1 - 4.2e-83 278.3 0.0 5.2e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 AET39134.1 - 0.00037 20.5 0.0 0.00077 19.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 AET39134.1 - 0.0011 19.7 0.0 0.003 18.3 0.0 1.8 1 0 0 1 1 1 1 Cytochrome c PHD PF00628.24 AET39135.1 - 2.7e-07 30.1 6.7 4.8e-07 29.3 4.6 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 AET39135.1 - 0.0046 17.2 2.2 0.0083 16.3 1.5 1.6 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 AET39135.1 - 0.014 15.4 2.6 0.034 14.2 1.8 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain MerR-DNA-bind PF09278.6 AET39135.1 - 0.05 14.0 0.8 0.092 13.1 0.6 1.5 1 0 0 1 1 1 0 MerR, DNA binding Sec8_exocyst PF04048.9 AET39135.1 - 0.053 13.1 0.6 0.09 12.4 0.4 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Ecl1 PF12855.2 AET39135.1 - 0.18 11.1 2.5 0.16 11.2 0.4 1.9 2 0 0 2 2 2 0 Life-span regulatory factor zf-RING-like PF08746.6 AET39135.1 - 3.3 7.7 6.8 2.6 8.1 3.1 2.2 2 0 0 2 2 2 0 RING-like domain Ribosomal_L3 PF00297.17 AET39136.1 - 1.8e-122 407.8 8.7 2.2e-122 407.5 6.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Pkinase PF00069.20 AET39137.1 - 9.5e-52 175.7 0.0 1.1e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39137.1 - 1.9e-15 56.6 0.0 2.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AET39137.1 - 8.4e-07 28.9 0.0 2.3e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AET39137.1 - 0.0073 15.8 0.1 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4402 PF14352.1 AET39138.1 - 0.16 12.4 8.2 0.32 11.4 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) DUF2894 PF11445.3 AET39138.1 - 0.17 12.1 4.5 0.24 11.6 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF676 PF05057.9 AET39139.1 - 2.4e-48 164.3 0.1 3.6e-48 163.7 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 AET39139.1 - 1.4e-05 24.8 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AET39139.1 - 0.00038 20.3 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 AET39139.1 - 0.00067 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) PGAP1 PF07819.8 AET39139.1 - 0.018 14.6 0.1 0.038 13.5 0.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein Sugar_tr PF00083.19 AET39142.1 - 8.4e-28 97.1 28.1 3.4e-19 68.7 4.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 AET39142.1 - 2.1e-19 69.4 41.9 7.9e-12 44.5 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sterol_MT_C PF08498.5 AET39143.1 - 1.9e-27 94.9 1.2 3.2e-27 94.2 0.8 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 AET39143.1 - 2.5e-18 66.3 0.0 4.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET39143.1 - 1.3e-12 47.5 0.0 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AET39143.1 - 4e-12 46.1 0.0 6.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET39143.1 - 2.7e-10 40.4 0.0 6.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AET39143.1 - 4.8e-10 38.9 0.0 7.2e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 AET39143.1 - 2.7e-09 36.5 0.1 3.8e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 AET39143.1 - 6.1e-09 36.4 0.0 1.2e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AET39143.1 - 2.7e-07 30.9 0.0 8.2e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 AET39143.1 - 8.3e-05 22.2 0.2 0.00013 21.5 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 AET39143.1 - 0.0026 17.7 0.0 0.014 15.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AET39143.1 - 0.032 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase bZIP_1 PF00170.16 AET39144.1 - 8.5e-07 28.8 16.7 1.9e-06 27.7 11.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Frigida PF07899.6 AET39144.1 - 0.32 9.7 3.9 0.53 9.0 2.7 1.2 1 0 0 1 1 1 0 Frigida-like protein Jnk-SapK_ap_N PF09744.4 AET39144.1 - 0.49 10.3 7.0 1 9.3 4.8 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_Maf PF03131.12 AET39144.1 - 0.69 10.2 22.2 0.081 13.2 10.2 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor APG6 PF04111.7 AET39144.1 - 4 6.4 8.2 0.15 11.0 1.7 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 AET39144.1 - 6.9 6.2 8.6 3.4 7.2 3.0 2.3 2 0 0 2 2 2 0 IncA protein AMPKBI PF04739.10 AET39145.1 - 2e-25 88.5 0.8 2e-25 88.5 0.5 2.0 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Kinesin PF00225.18 AET39146.1 - 3.6e-101 338.2 3.6 3.6e-101 338.2 2.5 1.6 2 0 0 2 2 2 1 Kinesin motor domain EzrA PF06160.7 AET39146.1 - 0.0016 16.7 6.9 0.0016 16.7 4.8 1.7 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA AAA_24 PF13479.1 AET39146.1 - 0.2 11.1 3.3 5.4 6.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain FlxA PF14282.1 AET39146.1 - 0.24 11.3 15.5 0.13 12.1 6.0 2.6 2 0 0 2 2 2 0 FlxA-like protein DUF972 PF06156.8 AET39146.1 - 0.24 11.7 7.4 3.1 8.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 AET39146.1 - 2.2 8.0 20.2 0.071 12.8 7.7 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Dynein_light PF01221.13 AET39147.1 - 2.6e-36 123.4 0.1 2.8e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 AET39147.1 - 0.064 13.5 0.0 0.08 13.2 0.0 1.1 1 0 0 1 1 1 0 Ground-like domain Fucose_iso_N2 PF07882.7 AET39147.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain PX PF00787.19 AET39148.1 - 1.2e-14 53.9 1.8 2.6e-14 52.9 0.0 2.4 3 0 0 3 3 3 1 PX domain YqzL PF14006.1 AET39148.1 - 0.018 15.2 0.2 0.056 13.6 0.1 1.9 1 0 0 1 1 1 0 YqzL-like protein Phage_GPO PF05929.6 AET39148.1 - 0.1 11.7 3.9 0.049 12.8 1.2 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF489 PF04356.7 AET39148.1 - 0.15 11.6 4.9 1.9 8.0 2.2 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF489) PCI PF01399.22 AET39149.1 - 3.9e-11 43.1 0.3 1.2e-10 41.6 0.2 1.8 1 0 0 1 1 1 1 PCI domain Spo0A_C PF08769.6 AET39149.1 - 0.0035 17.1 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 Sporulation initiation factor Spo0A C terminal PCI_Csn8 PF10075.4 AET39149.1 - 0.0085 15.8 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Abhydrolase_3 PF07859.8 AET39150.1 - 6.6e-10 38.9 0.0 9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AET39150.1 - 4.6e-06 26.4 0.0 6.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AET39150.1 - 3.2e-05 23.9 0.0 4.7e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 AET39150.1 - 0.0024 17.3 0.2 0.012 15.0 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 AET39150.1 - 0.014 14.9 0.1 0.037 13.5 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 AET39150.1 - 0.022 13.8 0.0 0.44 9.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 AET39150.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 AET39150.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.7 AET39150.1 - 0.18 11.0 1.2 0.19 11.0 0.1 1.6 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) eIF3g PF12353.3 AET39151.1 - 5e-42 142.8 0.2 8.5e-42 142.0 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 AET39151.1 - 7.7e-11 41.4 0.0 1.5e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET39151.1 - 5.7e-09 35.8 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET39151.1 - 5.6e-05 22.8 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 AET39151.1 - 0.092 12.4 0.2 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Zn_ribbon_2 PF12674.2 AET39151.1 - 0.12 12.6 1.0 0.21 11.9 0.1 1.9 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-CCHC_4 PF14392.1 AET39151.1 - 0.16 11.6 0.4 0.4 10.3 0.1 1.8 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L33 PF00471.15 AET39152.1 - 0.0026 17.9 0.3 0.0081 16.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L33 Spt5-NGN PF03439.8 AET39153.1 - 1.3e-21 76.1 0.0 2.9e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 AET39153.1 - 2.9e-17 61.6 6.6 0.00031 20.3 0.0 4.8 4 0 0 4 4 4 4 KOW motif Spt5_N PF11942.3 AET39153.1 - 4.7e-17 62.3 16.5 4.7e-17 62.3 11.4 3.6 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 AET39153.1 - 0.62 10.4 54.3 0.2 12.1 2.5 4.1 2 1 1 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Rad33 PF08730.5 AET39154.1 - 4.5e-38 130.3 1.7 6.3e-36 123.4 1.1 2.0 1 1 0 1 1 1 1 Rad33 EMP24_GP25L PF01105.19 AET39155.1 - 5.8e-40 136.9 0.6 6.6e-40 136.7 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Spc24 PF08286.6 AET39155.1 - 0.044 13.4 0.1 0.35 10.5 0.1 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2418 PF10332.4 AET39155.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) DUF1500 PF07389.7 AET39155.1 - 0.11 12.5 0.2 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) M16C_assoc PF08367.6 AET39156.1 - 2.1e-78 262.6 1.2 3.3e-78 261.9 0.9 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 AET39156.1 - 1.2e-25 90.2 0.0 9.5e-14 51.4 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AET39156.1 - 1.1e-06 28.5 0.1 4.9e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RRM_1 PF00076.17 AET39157.1 - 1.9e-27 94.6 0.4 4.6e-16 58.1 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET39157.1 - 6.2e-18 64.5 0.1 8.2e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET39157.1 - 1.4e-15 56.8 0.0 9.9e-11 41.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 AET39157.1 - 0.00096 19.0 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain Limkain-b1 PF11608.3 AET39157.1 - 0.08 12.7 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 UBX PF00789.15 AET39158.1 - 4.1e-11 42.7 0.3 1.2e-09 38.0 0.0 2.6 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 AET39158.1 - 4.7e-11 42.0 0.0 1e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain PIG-S PF10510.4 AET39159.1 - 3e-131 438.6 8.7 3.8e-131 438.2 6.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TAFII28 PF04719.9 AET39160.1 - 9.3e-24 83.0 1.6 4.6e-22 77.6 0.2 2.9 3 0 0 3 3 3 2 hTAFII28-like protein conserved region PBP1_TM PF14812.1 AET39160.1 - 0.57 10.5 5.3 1.9 8.8 0.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LCM PF04072.9 AET39161.1 - 5.4e-22 78.2 0.0 7.5e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Metallophos PF00149.23 AET39162.1 - 1.1e-38 132.6 0.2 1.7e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PIG-P PF08510.7 AET39163.1 - 5.9e-33 113.1 1.1 8.3e-33 112.6 0.8 1.2 1 0 0 1 1 1 1 PIG-P MFS_1 PF07690.11 AET39163.1 - 0.017 13.8 0.5 0.02 13.5 0.4 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily EamA PF00892.15 AET39165.1 - 1.5e-08 34.7 35.1 5e-05 23.3 3.0 3.7 3 1 1 4 4 4 2 EamA-like transporter family UAA PF08449.6 AET39165.1 - 4.3e-06 25.8 19.0 4.3e-06 25.8 13.2 1.7 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 AET39165.1 - 0.00014 21.5 11.2 0.00014 21.5 7.8 3.1 3 0 0 3 3 3 2 Triose-phosphate Transporter family MENTAL PF10457.4 AET39165.1 - 2.7 7.5 9.6 0.26 10.9 2.7 2.1 2 0 0 2 2 2 0 Cholesterol-capturing domain OST3_OST6 PF04756.8 AET39166.1 - 1.1e-16 60.8 10.0 1.7e-16 60.1 6.9 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 AET39166.1 - 0.0081 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin LRS4 PF10422.4 AET39167.1 - 7.7e-26 90.9 15.2 2e-25 89.6 10.6 1.7 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 DcpS_C PF11969.3 AET39167.1 - 0.097 12.9 0.4 0.19 11.9 0.3 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Atg14 PF10186.4 AET39167.1 - 0.19 10.6 9.9 0.36 9.7 6.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 AET39167.1 - 0.23 9.8 0.1 0.27 9.6 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 AET39167.1 - 0.9 9.9 10.4 1.9 8.8 4.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF2756 PF10956.3 AET39167.1 - 2.4 8.4 6.6 7.2 6.9 4.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2756) DivIC PF04977.10 AET39167.1 - 2.8 7.4 8.4 4.5 6.8 5.1 1.9 1 1 0 1 1 1 0 Septum formation initiator UDG PF03167.14 AET39169.1 - 9.2e-24 83.6 0.0 1.4e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DOT1 PF08123.8 AET39170.1 - 5.4e-86 287.1 0.7 1.5e-85 285.6 0.0 2.0 2 1 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 AET39170.1 - 0.0027 18.2 0.0 0.0055 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AET39170.1 - 0.023 13.7 0.6 0.16 11.0 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase Pribosyltran PF00156.22 AET39171.1 - 1.5e-15 56.9 0.0 1.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AET39171.1 - 0.0045 16.2 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Nse5 PF08691.5 AET39172.1 - 5.8e-99 331.9 3.6 7e-99 331.6 2.5 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Med13_C PF06333.7 AET39173.1 - 1.6e-90 303.6 10.9 3.3e-61 207.1 0.3 2.8 2 1 1 3 3 3 2 Mediator complex subunit 13 C-terminal DUF676 PF05057.9 AET39174.1 - 1.4e-48 165.1 0.0 2.1e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 AET39174.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 AET39174.1 - 0.0014 17.7 0.0 0.0037 16.3 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 AET39174.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 AET39174.1 - 0.026 14.4 0.0 0.044 13.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET39174.1 - 0.083 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AET39174.1 - 0.15 11.7 0.0 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family FAD-oxidase_C PF02913.14 AET39175.1 - 3e-49 167.5 0.0 9.3e-49 165.9 0.0 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AET39175.1 - 3.5e-35 120.4 0.1 7.9e-35 119.3 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain GAD PF02938.9 AET39175.1 - 0.11 12.6 0.1 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 GAD domain DUF3655 PF12379.3 AET39175.1 - 0.12 12.3 0.1 0.36 10.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3655) ECM11 PF15463.1 AET39176.1 - 1.1e-28 100.2 2.1 1.1e-28 100.2 1.4 1.6 2 0 0 2 2 2 1 Extracellular mutant protein 11 FliT PF05400.8 AET39176.1 - 5.7 7.4 6.6 1.6 9.2 0.7 2.6 2 1 1 3 3 3 0 Flagellar protein FliT Ribosomal_S17e PF00833.13 AET39177.1 - 3.3e-54 181.8 0.1 3.9e-54 181.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 ZZ PF00569.12 AET39178.1 - 6.1e-16 57.6 8.1 6.1e-16 57.6 5.6 1.8 2 0 0 2 2 2 1 Zinc finger, ZZ type SWIRM PF04433.12 AET39178.1 - 2.7e-14 53.0 0.3 1e-10 41.5 0.0 2.7 2 0 0 2 2 2 2 SWIRM domain Myb_DNA-binding PF00249.26 AET39178.1 - 5.6e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AET39178.1 - 0.006 16.6 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain U3_assoc_6 PF08640.6 AET39179.1 - 9.8e-32 108.5 11.4 2.4e-31 107.3 1.9 3.4 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 AET39179.1 - 0.00022 20.2 6.2 0.0019 17.1 1.7 2.2 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.9 AET39179.1 - 0.0026 17.5 9.7 0.0048 16.6 2.5 4.0 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) HAT PF02184.11 AET39179.1 - 0.061 13.0 1.3 0.6 9.8 0.2 2.4 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 AET39179.1 - 0.1 13.3 0.0 31 5.5 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat Ribosomal_L4 PF00573.17 AET39180.1 - 1.1e-47 161.8 0.0 1.4e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S13 PF00416.17 AET39181.1 - 3.8e-42 143.0 1.5 4.4e-42 142.8 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 AET39181.1 - 0.00013 20.6 0.1 0.00023 19.8 0.0 1.3 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 AET39181.1 - 0.057 13.4 0.2 0.25 11.3 0.1 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix motif Homeobox PF00046.24 AET39182.1 - 3.3e-17 61.8 6.7 6.8e-17 60.8 4.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AET39182.1 - 0.0026 17.4 0.2 0.0069 16.0 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain AhpC-TSA PF00578.16 AET39183.1 - 2.6e-34 117.5 0.0 2.8e-33 114.2 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 AET39183.1 - 6.3e-19 67.9 0.0 1.2e-18 67.0 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.4 AET39183.1 - 5.1e-07 29.2 0.0 9.4e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin ubiquitin PF00240.18 AET39184.1 - 0.00061 19.1 0.0 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family HIG_1_N PF04588.8 AET39185.1 - 2.8e-20 71.7 0.6 4.1e-20 71.2 0.4 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1068 PF06364.7 AET39185.1 - 0.027 14.0 4.6 0.058 13.0 3.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1068) Dynactin_p62 PF05502.8 AET39185.1 - 0.1 11.3 1.9 0.12 11.0 1.3 1.1 1 0 0 1 1 1 0 Dynactin p62 family Pox_A51 PF04948.8 AET39185.1 - 0.14 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein OmpH PF03938.9 AET39185.1 - 0.15 12.0 6.3 0.17 11.8 4.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 AET39185.1 - 0.44 10.8 3.1 0.5 10.6 2.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4485 PF14846.1 AET39185.1 - 0.58 9.9 4.1 0.51 10.0 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) DFF40 PF09230.5 AET39185.1 - 2.4 7.4 6.9 4 6.7 4.8 1.5 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa Guanylate_kin PF00625.16 AET39186.1 - 1e-69 233.6 0.0 1.1e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 AET39186.1 - 8.4e-06 25.8 0.0 3.3e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AET39186.1 - 1.2e-05 25.1 0.0 6e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AET39186.1 - 2.3e-05 25.2 0.0 4.3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AET39186.1 - 2.9e-05 24.3 0.0 6.4e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AET39186.1 - 3.7e-05 23.8 0.1 0.0001 22.4 0.0 1.8 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 AET39186.1 - 8.3e-05 22.7 0.1 0.00023 21.2 0.1 1.8 2 1 0 2 2 1 1 RNA helicase Miro PF08477.8 AET39186.1 - 0.00027 21.4 0.1 0.00058 20.3 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_19 PF13245.1 AET39186.1 - 0.00082 19.0 0.1 0.0031 17.2 0.0 2.0 2 1 0 2 2 2 1 Part of AAA domain AAA PF00004.24 AET39186.1 - 0.0015 18.7 0.2 0.0028 17.8 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AET39186.1 - 0.0018 18.0 0.1 0.0042 16.8 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_28 PF13521.1 AET39186.1 - 0.0021 18.0 0.0 0.006 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AET39186.1 - 0.0025 16.7 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 AET39186.1 - 0.0026 17.6 0.0 0.0045 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 AET39186.1 - 0.0036 17.2 0.0 0.0076 16.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AET39186.1 - 0.0043 16.2 0.0 0.0073 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 AET39186.1 - 0.0045 17.2 0.0 0.0054 17.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 AET39186.1 - 0.005 16.5 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 AET39186.1 - 0.0099 15.3 0.5 0.03 13.7 0.2 1.8 1 1 1 2 2 2 1 AAA-like domain AAA_29 PF13555.1 AET39186.1 - 0.01 15.3 0.3 0.025 14.0 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 AET39186.1 - 0.013 15.1 0.2 0.04 13.5 0.2 1.8 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.4 AET39186.1 - 0.021 13.8 0.0 0.039 12.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 AET39186.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.9 AET39186.1 - 0.035 13.0 0.0 0.066 12.1 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain Rad17 PF03215.10 AET39186.1 - 0.038 12.6 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 AET39186.1 - 0.061 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 AET39186.1 - 0.086 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 AET39186.1 - 0.096 12.1 0.1 0.19 11.2 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 AET39186.1 - 0.096 12.0 1.0 0.49 9.7 0.2 2.2 2 1 1 3 3 3 0 AAA domain KTI12 PF08433.5 AET39186.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 AET39186.1 - 0.12 12.6 2.5 0.38 11.0 1.7 1.9 1 1 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.16 AET39187.1 - 3.3e-64 216.7 38.1 4.1e-64 216.4 26.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.1 AET39187.1 - 0.021 14.4 0.6 0.05 13.2 0.4 1.6 1 0 0 1 1 1 0 Myc target protein 1 K1 PF02960.9 AET39187.1 - 0.36 10.8 3.6 0.39 10.7 0.2 2.4 2 0 0 2 2 2 0 K1 glycoprotein Ndc1_Nup PF09531.5 AET39188.1 - 6.4e-123 411.3 26.3 1.1e-122 410.5 18.2 1.3 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Rad52_Rad22 PF04098.10 AET39189.1 - 8.7e-57 191.1 0.0 1.3e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein HECT PF00632.20 AET39190.1 - 9.4e-90 300.9 0.2 8.4e-89 297.8 0.0 2.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 AET39190.1 - 5.2e-79 265.9 5.8 5.2e-79 265.9 4.0 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 AET39190.1 - 1.9e-42 145.4 0.2 1.9e-42 145.4 0.1 3.0 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 AET39190.1 - 1e-13 51.1 5.3 1e-13 51.1 3.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) MSC PF09402.5 AET39191.1 - 6.9e-124 412.8 9.5 1.2e-123 412.1 6.6 1.4 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 AET39191.1 - 2.3e-12 46.2 0.1 6.1e-12 44.8 0.1 1.8 1 0 0 1 1 1 1 HeH/LEM domain Bro-N PF02498.12 AET39191.1 - 0.058 13.6 0.8 0.23 11.7 0.0 2.4 2 0 0 2 2 2 0 BRO family, N-terminal domain EF-hand_1 PF00036.27 AET39191.1 - 0.11 11.8 0.4 3.9 7.0 0.1 2.9 2 0 0 2 2 2 0 EF hand A_deaminase PF00962.17 AET39192.1 - 6.4e-116 386.8 0.1 8.7e-116 386.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-DHHC PF01529.15 AET39193.1 - 3e-26 91.8 10.5 3e-26 91.8 7.3 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase ABC2_membrane_3 PF12698.2 AET39193.1 - 1.5 7.7 14.6 0.038 13.0 5.3 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4149 PF13664.1 AET39193.1 - 6.6 6.8 12.1 0.14 12.2 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) MAT1 PF06391.8 AET39194.1 - 1e-55 188.4 29.5 1.6e-55 187.8 20.5 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 AET39194.1 - 0.0023 17.5 4.9 0.004 16.7 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AET39194.1 - 0.0029 17.2 4.3 0.01 15.4 3.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET39194.1 - 0.0034 17.3 6.2 0.0091 16.0 4.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET39194.1 - 0.0073 16.1 5.8 0.014 15.1 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AET39194.1 - 0.098 12.4 9.0 0.78 9.5 6.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-piccolo PF05715.8 AET39194.1 - 0.099 12.6 1.1 0.2 11.7 0.8 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_UBOX PF13445.1 AET39194.1 - 0.36 10.5 4.0 0.98 9.1 2.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger 3HCDH_N PF02737.13 AET39194.1 - 0.39 10.3 3.9 0.65 9.6 2.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RING_4 PF14570.1 AET39194.1 - 1.1 8.8 9.5 10 5.8 6.6 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain 3H PF02829.9 AET39194.1 - 1.6 8.7 6.0 0.34 10.9 0.7 2.3 2 1 1 3 3 3 0 3H domain CGI-121 PF08617.5 AET39195.1 - 1.3e-33 115.9 0.9 1.6e-33 115.6 0.6 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Sel1 PF08238.7 AET39196.1 - 4.2e-32 109.8 5.2 0.00021 21.8 0.0 7.5 8 0 0 8 8 8 6 Sel1 repeat DUF3767 PF12597.3 AET39197.1 - 6.2e-40 135.5 0.5 8.6e-40 135.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3353 PF11833.3 AET39197.1 - 0.048 13.1 0.2 0.061 12.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) DUF1019 PF06254.6 AET39197.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) LigB PF02900.13 AET39198.1 - 1.5e-32 112.6 0.0 2.3e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Ribosomal_L10 PF00466.15 AET39200.1 - 5.2e-08 32.7 0.0 9.5e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.12 AET39201.1 - 4.3e-58 195.6 0.0 5.6e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AET39201.1 - 3.9e-05 24.2 0.0 7.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET39201.1 - 0.00012 21.6 0.0 0.00027 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET39201.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET39201.1 - 0.0031 17.8 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AET39201.1 - 0.0064 15.8 0.0 0.015 14.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 AET39201.1 - 0.0069 16.8 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AET39201.1 - 0.0078 15.3 0.0 0.027 13.6 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FmrO PF07091.6 AET39201.1 - 0.0099 14.8 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 AET39201.1 - 0.044 14.2 0.0 1.6 9.2 0.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain DUF257 PF03192.8 AET39201.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Mito_carr PF00153.22 AET39202.1 - 4.6e-29 99.9 0.7 3.8e-14 52.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein CFIA_Pcf11 PF11526.3 AET39203.1 - 5.5e-24 84.1 3.5 5.5e-24 84.1 2.5 2.2 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 zf-RING_2 PF13639.1 AET39203.1 - 0.14 12.0 1.6 0.18 11.6 0.2 1.8 2 0 0 2 2 2 0 Ring finger domain OmpH PF03938.9 AET39203.1 - 2 8.3 21.9 0.58 10.0 12.4 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ApoO PF09769.4 AET39203.1 - 2.3 7.9 5.3 5.4 6.7 3.4 1.8 1 1 0 1 1 1 0 Apolipoprotein O DUF641 PF04859.7 AET39204.1 - 9.5 5.9 14.2 0.2 11.4 0.4 3.5 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) ADK PF00406.17 AET39206.1 - 2.3e-61 206.1 0.0 2.7e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 AET39206.1 - 3e-14 52.3 0.0 8.9e-14 50.8 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 AET39206.1 - 1.1e-06 28.6 0.0 2e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AET39206.1 - 0.00018 22.2 0.0 0.00037 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AET39206.1 - 0.00045 20.5 0.0 0.001 19.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AET39206.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AET39206.1 - 0.074 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AET39206.1 - 0.081 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 AET39206.1 - 0.1 12.7 0.1 1.6 8.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain zf-C2H2 PF00096.21 AET39207.1 - 3.8e-10 39.4 13.5 1.2e-05 25.3 0.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET39207.1 - 1.5e-07 31.3 13.9 1.3e-05 25.1 0.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET39207.1 - 2.1e-07 30.7 11.8 0.00019 21.5 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 AET39207.1 - 7.8e-06 25.9 6.7 0.002 18.2 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AET39207.1 - 0.00034 20.6 2.8 0.056 13.6 0.0 2.7 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 AET39207.1 - 0.0082 15.7 4.1 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 AET39207.1 - 0.017 15.2 3.0 1.5 9.0 0.1 2.7 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 AET39207.1 - 0.018 14.9 3.0 3.6 7.6 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.9 AET39207.1 - 0.028 14.0 0.6 2.3 7.9 0.2 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif UPF0547 PF10571.4 AET39207.1 - 0.037 13.7 2.2 0.093 12.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CpXC PF14353.1 AET39207.1 - 0.057 13.3 1.4 0.33 10.9 1.0 2.0 1 1 0 1 1 1 0 CpXC protein zf-C2H2_2 PF12756.2 AET39207.1 - 0.13 12.4 4.4 14 5.8 0.4 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.4 AET39207.1 - 0.47 10.2 5.3 0.73 9.6 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.10 AET39207.1 - 1 9.1 9.0 1.5 8.6 0.7 3.0 2 1 1 3 3 3 0 BED zinc finger Zn-ribbon_8 PF09723.5 AET39207.1 - 1.3 9.0 5.6 18 5.3 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DUF3992 PF13157.1 AET39208.1 - 1.4 9.1 4.2 2.8 8.1 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) Histone PF00125.19 AET39209.1 - 3.5e-26 91.1 0.0 4.8e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AET39209.1 - 4.3e-06 26.6 0.0 6.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AET39210.1 - 2.5e-22 78.7 0.3 3.5e-22 78.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AET39210.1 - 3.2e-06 27.1 0.1 7.6e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 AET39210.1 - 0.0017 18.6 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF601 PF04642.7 AET39210.1 - 0.35 10.2 5.9 0.41 9.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 RNA_pol_Rpb2_1 PF04563.10 AET39210.1 - 1.2 8.0 4.1 5.5 5.8 0.8 2.0 1 1 1 2 2 2 0 RNA polymerase beta subunit VIT1 PF01988.14 AET39211.1 - 3.1e-56 190.2 0.4 4.3e-56 189.7 0.3 1.2 1 0 0 1 1 1 1 VIT family Peptidase_M30 PF10460.4 AET39211.1 - 0.081 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase M30 Rsa3 PF14615.1 AET39212.1 - 1.2e-22 78.9 0.4 2.2e-22 78.0 0.3 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SR-25 PF10500.4 AET39212.1 - 0.039 13.4 12.4 0.048 13.1 8.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM178 PF14816.1 AET39212.1 - 0.35 9.5 4.0 0.47 9.1 2.8 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 BUD22 PF09073.5 AET39212.1 - 0.67 8.9 14.3 0.79 8.7 9.9 1.1 1 0 0 1 1 1 0 BUD22 Myc_N PF01056.13 AET39212.1 - 0.99 8.5 8.2 1.3 8.0 5.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region SLX9 PF15341.1 AET39212.1 - 3.1 8.2 12.7 4.5 7.7 8.4 1.5 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 WD40 PF00400.27 AET39213.1 - 3.8e-65 213.6 20.3 1e-09 37.8 0.0 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.6 AET39213.1 - 3.6e-52 175.7 0.4 6.5e-52 174.9 0.3 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 AET39213.1 - 5e-08 31.5 9.1 0.021 12.9 0.1 6.4 4 2 2 7 7 7 4 Nucleoporin Nup120/160 CPSF_A PF03178.10 AET39213.1 - 0.00069 18.7 0.6 0.03 13.4 0.1 2.5 2 0 0 2 2 2 1 CPSF A subunit region Nucleoporin_N PF08801.6 AET39213.1 - 0.001 17.9 6.4 1.4 7.5 0.0 4.9 3 2 1 5 5 5 2 Nup133 N terminal like FmdE PF02663.9 AET39213.1 - 0.01 15.7 0.1 0.047 13.5 0.1 2.1 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon CRF1 PF10380.4 AET39214.1 - 2.7e-34 118.1 1.7 2.7e-34 118.1 1.2 4.0 3 1 0 3 3 3 1 Transcription factor CRF1 Toxin_63 PF15541.1 AET39214.1 - 0.015 15.2 0.0 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 Putative toxin 63 PRKCSH-like PF12999.2 AET39215.1 - 6.5e-46 156.1 5.6 6.5e-46 156.1 3.9 2.7 1 1 2 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 AET39215.1 - 2.3e-22 79.1 9.7 7.4e-22 77.4 0.4 3.9 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein DRIM PF07539.7 AET39215.1 - 0.0011 18.4 0.2 0.003 16.9 0.1 1.8 1 0 0 1 1 1 1 Down-regulated in metastasis PRKCSH PF07915.8 AET39215.1 - 0.013 16.2 0.0 0.032 15.0 0.0 1.7 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein FliH PF02108.11 AET39215.1 - 0.081 12.8 0.8 0.34 10.7 0.0 2.3 2 0 0 2 2 2 0 Flagellar assembly protein FliH DUF1664 PF07889.7 AET39215.1 - 7 6.4 7.9 17 5.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) F-box-like PF12937.2 AET39216.1 - 1.3e-05 24.7 0.0 3.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AET39216.1 - 0.00015 21.3 0.0 0.00033 20.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 AET39216.1 - 0.057 13.3 1.2 0.55 10.2 0.0 2.8 3 1 0 3 3 3 0 PRANC domain Septin PF00735.13 AET39218.1 - 2e-81 273.1 3.4 1.2e-80 270.5 2.4 1.9 1 1 0 1 1 1 1 Septin Dynamin_N PF00350.18 AET39218.1 - 0.00019 21.2 0.1 0.00066 19.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin family AAA_17 PF13207.1 AET39218.1 - 0.00033 21.4 0.1 0.0023 18.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 AET39218.1 - 0.00085 18.3 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 AET39218.1 - 0.00092 19.3 0.0 0.0037 17.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 AET39218.1 - 0.0032 16.9 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 AET39218.1 - 0.004 17.0 0.2 0.01 15.7 0.0 1.9 2 1 0 2 2 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AET39218.1 - 0.0055 17.0 1.6 0.021 15.1 0.1 2.4 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 AET39218.1 - 0.0055 17.2 0.0 0.016 15.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AET39218.1 - 0.006 16.0 0.1 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 AET39218.1 - 0.0072 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Pox_A32 PF04665.7 AET39218.1 - 0.0088 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein G-alpha PF00503.15 AET39218.1 - 0.01 14.5 5.6 0.07 11.7 0.0 3.5 3 1 1 4 4 4 1 G-protein alpha subunit MobB PF03205.9 AET39218.1 - 0.012 15.3 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 AET39218.1 - 0.012 15.9 0.3 0.05 13.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 AET39218.1 - 0.015 14.7 0.1 0.056 12.8 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 AET39218.1 - 0.017 14.9 0.0 0.061 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AET39218.1 - 0.019 14.6 0.0 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 AET39218.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase ATP_bind_1 PF03029.12 AET39218.1 - 0.085 12.3 0.0 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 AET39218.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 AET39218.1 - 3.6 7.8 8.4 2.2 8.5 3.6 2.4 2 1 0 2 2 2 0 AAA domain Rad9_Rad53_bind PF08605.5 AET39220.1 - 5.6e-41 139.3 0.2 1.5e-40 137.9 0.1 1.8 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 AET39220.1 - 3.6e-08 33.4 0.5 1.6e-07 31.3 0.3 2.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Aha1_N PF09229.6 AET39221.1 - 6.1e-34 116.7 0.0 1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 AET39221.1 - 4.5e-10 39.6 0.0 7.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Drc1-Sld2 PF11719.3 AET39221.1 - 0.13 11.2 0.0 0.28 10.2 0.0 1.3 1 1 0 1 1 1 0 DNA replication and checkpoint protein Fungal_trans_2 PF11951.3 AET39222.1 - 3e-12 45.8 0.5 3e-12 45.8 0.4 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET39222.1 - 1.6e-06 27.9 18.4 2.8e-06 27.1 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Band_3_cyto PF07565.8 AET39222.1 - 0.17 11.3 21.9 0.48 9.8 15.2 1.8 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAT1 PF09770.4 AET39222.1 - 8.4 4.4 57.9 13 3.8 40.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cpn60_TCP1 PF00118.19 AET39223.1 - 1.2e-140 469.3 10.7 1.4e-140 469.1 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.17 AET39224.1 - 3e-51 173.0 0.0 3.6e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET39224.1 - 9.7e-14 51.8 0.0 1.3e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET39224.1 - 1.3e-07 31.0 0.0 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family W2 PF02020.13 AET39225.1 - 3.1e-15 55.8 0.5 1.4e-14 53.8 0.1 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.18 AET39225.1 - 5e-11 42.3 0.0 1.4e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 AET39225.1 - 9.3e-09 34.4 17.3 0.007 15.8 0.2 4.4 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AET39225.1 - 0.00071 19.0 15.7 0.0097 15.4 1.2 3.5 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 AET39225.1 - 0.0076 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain PIP5K PF01504.13 AET39226.1 - 1.6e-83 279.6 0.5 2.4e-83 279.1 0.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase E1-E2_ATPase PF00122.15 AET39227.1 - 6.4e-64 215.1 6.8 1.3e-63 214.0 4.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AET39227.1 - 1.8e-34 118.8 4.0 1.8e-34 118.8 2.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AET39227.1 - 1.6e-28 100.6 0.0 8.5e-27 94.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AET39227.1 - 1.6e-17 63.2 0.1 3.8e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AET39227.1 - 5e-14 52.9 0.0 1.3e-13 51.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AET39227.1 - 5.6e-13 48.1 0.0 1.4e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AET39227.1 - 0.0013 18.3 0.8 0.0071 15.9 0.9 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aminotran_5 PF00266.14 AET39228.1 - 9.1e-17 60.8 0.0 1.3e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AET39228.1 - 0.023 13.7 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family EST1_DNA_bind PF10373.4 AET39229.1 - 6e-48 163.4 0.2 6e-48 163.4 0.1 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 AET39229.1 - 6.4e-27 94.1 8.1 4.3e-25 88.2 2.4 2.6 2 0 0 2 2 2 2 Telomerase activating protein Est1 TPR_11 PF13414.1 AET39229.1 - 0.17 11.5 0.0 0.53 9.9 0.0 1.8 2 0 0 2 2 2 0 TPR repeat Zn_clus PF00172.13 AET39230.1 - 3.4e-11 42.8 7.5 5.8e-11 42.1 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.8 AET39230.1 - 0.00032 20.7 0.6 0.00032 20.7 0.4 3.0 2 2 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Topoisom_bac PF01131.15 AET39231.1 - 1.1e-93 314.3 0.0 1.2e-93 314.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 AET39231.1 - 2.3e-17 62.8 0.0 4.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Cation_efflux PF01545.16 AET39232.1 - 1.3e-52 178.6 8.9 1.3e-52 178.6 6.2 3.2 3 1 0 3 3 3 1 Cation efflux family Zip PF02535.17 AET39232.1 - 2.2e-05 23.6 21.8 2.2e-05 23.6 15.1 2.4 3 1 0 3 3 3 1 ZIP Zinc transporter Coq4 PF05019.8 AET39233.1 - 1e-84 282.9 0.1 1.3e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Rogdi_lz PF10259.4 AET39234.1 - 1.2e-75 254.2 0.9 1.3e-75 254.0 0.6 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Eclosion PF04736.7 AET39234.1 - 0.09 12.2 0.1 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Eclosion hormone DASH_Spc19 PF08287.6 AET39235.1 - 1.9e-44 150.9 12.2 2.1e-44 150.8 8.5 1.0 1 0 0 1 1 1 1 Spc19 DUF4515 PF14988.1 AET39235.1 - 0.0063 16.2 8.6 0.0063 16.2 6.0 2.5 2 2 0 2 2 2 1 Domain of unknown function (DUF4515) DUF848 PF05852.6 AET39235.1 - 0.0063 16.3 2.4 0.0063 16.3 1.7 1.9 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) Sds3 PF08598.6 AET39235.1 - 0.014 14.9 3.2 0.024 14.1 2.2 1.6 1 1 0 1 1 1 0 Sds3-like Fib_alpha PF08702.5 AET39235.1 - 0.021 14.9 5.8 0.052 13.6 1.4 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3209 PF11483.3 AET39235.1 - 0.083 13.2 0.4 0.17 12.2 0.1 1.8 2 1 0 2 2 1 0 Protein of unknown function (DUF3209) FtsQ PF03799.10 AET39235.1 - 0.095 12.8 0.1 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 Cell division protein FtsQ Prefoldin_2 PF01920.15 AET39235.1 - 0.15 11.8 12.4 0.21 11.3 0.1 3.0 3 0 0 3 3 3 0 Prefoldin subunit DUF1795 PF08786.6 AET39235.1 - 0.22 11.3 1.4 0.84 9.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1795) Taxilin PF09728.4 AET39235.1 - 0.29 10.1 10.3 0.46 9.5 7.2 1.3 1 1 0 1 1 1 0 Myosin-like coiled-coil protein AAA_23 PF13476.1 AET39235.1 - 0.29 11.4 7.1 0.35 11.1 4.9 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 AET39235.1 - 0.33 10.6 7.0 0.47 10.2 1.2 2.3 2 1 0 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.4 AET39235.1 - 0.4 10.8 7.5 1.4 9.1 0.4 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2951 PF11166.3 AET39235.1 - 0.48 10.3 6.5 0.18 11.6 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) CorA PF01544.13 AET39235.1 - 0.69 8.8 3.7 0.23 10.4 0.8 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF342 PF03961.8 AET39235.1 - 0.96 7.7 5.5 0.55 8.5 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FadA PF09403.5 AET39235.1 - 1 9.4 6.5 1.4 8.9 0.2 2.4 2 1 0 2 2 2 0 Adhesion protein FadA DivIVA PF05103.8 AET39235.1 - 1 9.4 6.2 0.64 10.0 1.2 2.1 2 0 0 2 2 2 0 DivIVA protein IncA PF04156.9 AET39235.1 - 1.5 8.3 14.4 1.9 8.0 5.7 2.1 2 0 0 2 2 2 0 IncA protein TBCA PF02970.11 AET39235.1 - 1.8 8.6 8.3 3.5 7.7 1.6 2.9 2 1 1 3 3 3 0 Tubulin binding cofactor A Spc7 PF08317.6 AET39235.1 - 1.9 7.0 11.7 1.1 7.8 4.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 AET39235.1 - 2.8 7.7 12.5 4.3 7.1 0.5 3.0 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 AET39235.1 - 3.3 6.6 12.7 0.56 9.2 4.9 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Spc24 PF08286.6 AET39235.1 - 3.9 7.2 11.5 1.2 8.8 0.4 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 AET39235.1 - 3.9 7.1 9.5 2.1 8.0 0.3 3.0 3 0 0 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 AET39235.1 - 5.6 6.7 6.5 3.5 7.4 0.6 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FHA PF00498.21 AET39236.1 - 1.1e-17 63.9 2.9 3.1e-17 62.4 0.1 2.9 3 1 0 3 3 3 1 FHA domain Phage_GPO PF05929.6 AET39236.1 - 0.037 13.2 5.5 0.059 12.6 3.8 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Band_7_1 PF13421.1 AET39236.1 - 0.072 12.5 2.2 0.13 11.7 1.5 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Exonuc_VII_L PF02601.10 AET39236.1 - 0.56 9.3 13.4 0.87 8.7 9.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ACCA PF03255.9 AET39236.1 - 5.8 6.4 8.9 1.1 8.8 3.2 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit BPL_LplA_LipB PF03099.14 AET39237.1 - 1e-17 64.3 0.1 1.8e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SET PF00856.23 AET39238.1 - 0.025 14.8 0.2 0.081 13.2 0.1 1.8 1 1 0 1 1 1 0 SET domain ApbA_C PF08546.6 AET39239.1 - 9e-20 70.9 0.0 1.3e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal CoaE PF01121.15 AET39240.1 - 7.8e-61 204.6 0.0 1.1e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 AET39240.1 - 4.9e-06 27.3 0.1 1.6e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 AET39240.1 - 8.5e-05 22.5 1.8 0.032 14.1 0.0 3.1 3 0 0 3 3 3 1 Cytidylate kinase-like family AAA_18 PF13238.1 AET39240.1 - 0.03 14.6 1.6 0.094 13.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain PRK PF00485.13 AET39240.1 - 0.046 13.2 0.6 0.098 12.2 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 AET39240.1 - 0.057 13.2 0.0 0.34 10.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain SKI PF01202.17 AET39240.1 - 0.067 13.0 0.7 0.23 11.3 0.0 2.2 3 0 0 3 3 3 0 Shikimate kinase Herpes_UL69 PF05459.7 AET39240.1 - 0.091 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family NPV_P10 PF05531.7 AET39241.1 - 0.036 14.3 0.3 0.091 13.0 0.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3665 PF12427.3 AET39241.1 - 0.05 12.9 0.1 0.05 12.9 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase DEAD PF00270.24 AET39242.1 - 3.9e-40 137.1 0.9 2.5e-38 131.2 0.1 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AET39242.1 - 1.9e-18 66.1 0.0 5.3e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET39242.1 - 3.8e-05 23.6 0.3 3.8e-05 23.6 0.2 2.4 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AET39242.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PI3Ka PF00613.15 AET39243.1 - 3.4e-66 221.9 1.1 5.6e-66 221.2 0.8 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 AET39243.1 - 2e-46 158.3 0.4 8e-45 153.1 0.0 3.3 3 2 1 4 4 4 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 AET39243.1 - 5.6e-22 78.0 0.0 1.7e-21 76.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF221 PF02714.10 AET39244.1 - 1.6e-95 319.6 16.7 1.6e-95 319.6 11.6 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AET39244.1 - 1.3e-38 131.9 0.4 1.3e-38 131.9 0.3 2.7 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 AET39244.1 - 8.7e-12 45.3 0.0 3.4e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 AET39244.1 - 0.052 13.5 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Arv1 PF04161.8 AET39245.1 - 7.4e-74 248.1 16.5 7.4e-74 248.1 11.4 1.4 2 0 0 2 2 2 1 Arv1-like family zf-CCCH PF00642.19 AET39246.1 - 1.1e-05 25.0 3.7 2e-05 24.1 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ATP_bind_1 PF03029.12 AET39247.1 - 1.8e-87 292.8 0.0 2e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 AET39247.1 - 7.6e-05 23.5 0.1 0.00015 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AET39247.1 - 0.00014 21.4 0.0 0.00037 20.0 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain GTP_EFTU PF00009.22 AET39247.1 - 0.00038 19.9 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.14 AET39247.1 - 0.00054 19.4 0.1 0.0057 16.1 0.0 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 AET39247.1 - 0.00084 18.9 0.0 0.0059 16.2 0.0 2.2 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 AET39247.1 - 0.0022 17.7 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 AET39247.1 - 0.0027 16.5 0.1 0.006 15.3 0.0 1.5 2 0 0 2 2 2 1 ArgK protein T2SE PF00437.15 AET39247.1 - 0.0042 16.0 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 AET39247.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 AET39247.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain KAP_NTPase PF07693.9 AET39247.1 - 0.007 15.3 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.24 AET39247.1 - 0.0071 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AET39247.1 - 0.0074 16.4 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 AET39247.1 - 0.0077 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 AET39247.1 - 0.013 15.6 0.0 0.05 13.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_16 PF13191.1 AET39247.1 - 0.018 15.0 0.0 0.093 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 AET39247.1 - 0.018 15.3 0.0 0.052 13.8 0.0 1.8 2 1 0 2 2 1 0 ABC transporter NACHT PF05729.7 AET39247.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 AET39247.1 - 0.02 14.4 0.1 0.073 12.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 AET39247.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AET39247.1 - 0.025 14.2 0.0 0.41 10.2 0.0 2.1 2 1 0 2 2 2 0 Archaeal ATPase SRP54 PF00448.17 AET39247.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 AET39247.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_33 PF13671.1 AET39247.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AET39247.1 - 0.041 13.7 0.0 0.097 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AET39247.1 - 0.05 12.7 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 AET39247.1 - 0.055 13.7 0.1 0.16 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 AET39247.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RecA PF00154.16 AET39247.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_29 PF13555.1 AET39247.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.10 AET39247.1 - 0.085 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase FtsK_SpoIIIE PF01580.13 AET39247.1 - 0.094 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Septin PF00735.13 AET39247.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_25 PF13481.1 AET39247.1 - 0.11 11.8 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 AET39247.1 - 0.12 11.9 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 AET39247.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 AET39247.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF258 PF03193.11 AET39247.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 AET39247.1 - 0.17 10.5 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SIR2 PF02146.12 AET39248.1 - 2.9e-30 105.2 0.0 7.9e-30 103.8 0.0 1.6 1 1 0 1 1 1 1 Sir2 family DUF3039 PF11238.3 AET39248.1 - 0.37 10.2 3.4 2.3 7.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) TIP49 PF06068.8 AET39249.1 - 3.6e-186 618.6 0.2 4.1e-186 618.4 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 AET39249.1 - 2.3e-08 33.3 1.6 0.00014 20.9 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 AET39249.1 - 4.5e-08 33.3 0.2 6.9e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 AET39249.1 - 0.0011 19.0 0.1 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AET39249.1 - 0.0013 18.7 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 AET39249.1 - 0.0082 15.2 0.2 0.019 14.0 0.1 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 AET39249.1 - 0.0093 15.8 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AET39249.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DnaB_C PF03796.10 AET39249.1 - 0.02 13.7 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain CPT PF07931.7 AET39249.1 - 0.034 13.7 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.16 AET39249.1 - 0.048 12.8 0.1 5.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AET39249.1 - 0.059 12.8 0.0 6.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 AET39249.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AET39249.1 - 0.1 12.3 0.2 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sec1 PF00995.18 AET39250.1 - 1.8e-142 475.8 2.3 2.1e-142 475.6 1.6 1.0 1 0 0 1 1 1 1 Sec1 family HTH_25 PF13413.1 AET39250.1 - 0.00029 20.4 0.1 0.00084 18.9 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Cpn60_TCP1 PF00118.19 AET39251.1 - 6e-143 476.9 0.9 6.8e-143 476.8 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family dCMP_cyt_deam_1 PF00383.17 AET39252.1 - 5.4e-15 54.8 0.4 6.8e-15 54.5 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 AET39252.1 - 6.3e-10 39.1 0.1 2.3e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region YliH PF10799.3 AET39252.1 - 0.032 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) LmjF365940-deam PF14421.1 AET39252.1 - 0.074 12.4 2.7 2.3 7.5 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases TFIIA PF03153.8 AET39253.1 - 2.3 8.0 20.8 0.016 15.0 8.1 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Trypan_PARP PF05887.6 AET39253.1 - 3.3 7.5 4.8 6.8 6.5 3.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-DHHC PF01529.15 AET39254.1 - 1.2e-34 119.1 8.4 1.2e-34 119.1 5.9 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF2645 PF10840.3 AET39254.1 - 0.019 15.1 1.9 0.019 15.1 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) PRELI PF04707.9 AET39255.1 - 2.2e-56 189.7 0.6 3e-56 189.3 0.4 1.1 1 0 0 1 1 1 1 PRELI-like family DUF2216 PF10226.4 AET39256.1 - 0.0088 15.5 0.5 0.018 14.5 0.4 1.5 1 0 0 1 1 1 1 Uncharacterized conserved proteins (DUF2216) PAAR_motif PF05488.8 AET39256.1 - 0.029 14.3 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 PAAR motif ubiquitin PF00240.18 AET39257.1 - 1.1e-34 117.6 0.9 2.7e-34 116.3 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 AET39257.1 - 1.8e-25 88.4 1.1 3.4e-25 87.6 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 AET39257.1 - 5.3e-20 70.8 1.1 1e-19 69.9 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AET39257.1 - 8.6e-06 25.9 0.4 3.9e-05 23.8 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AET39257.1 - 0.00011 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AET39257.1 - 0.00096 19.0 0.4 0.0025 17.6 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AET39257.1 - 0.0038 17.3 0.4 0.005 17.0 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 AET39257.1 - 0.0094 15.8 0.4 0.014 15.2 0.3 1.3 1 0 0 1 1 1 1 IBR domain DUF2870 PF11069.3 AET39257.1 - 0.067 13.2 0.3 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 AET39257.1 - 0.15 11.9 0.5 0.27 11.0 0.2 1.6 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Plexin_cytopl PF08337.7 AET39257.1 - 0.16 10.2 2.0 5 5.3 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Phosducin PF02114.11 AET39258.1 - 4.3e-08 32.2 0.1 5.2e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 AET39258.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Sigma70_r1_1 PF03979.9 AET39258.1 - 0.035 14.0 0.3 0.071 13.0 0.2 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Sec10 PF07393.6 AET39259.1 - 6e-189 629.6 25.5 7.2e-189 629.4 17.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Metallophos PF00149.23 AET39260.1 - 2.8e-17 62.7 1.8 4.6e-17 62.0 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAS4 PF15460.1 AET39261.1 - 5.1e-30 103.3 8.6 1.5e-29 101.7 5.9 1.8 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Nipped-B_C PF12830.2 AET39262.1 - 5.8e-45 153.2 6.7 3e-44 150.9 0.4 4.0 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 AET39262.1 - 1.7e-13 50.1 0.8 5.3e-12 45.4 0.3 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 AET39262.1 - 0.0064 16.7 0.1 17 5.7 0.0 4.1 3 0 0 3 3 3 1 HEAT repeats PseudoU_synth_2 PF00849.17 AET39263.1 - 3.6e-17 62.6 0.0 2.1e-15 56.9 0.0 2.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase Endonuc-MspI PF09208.5 AET39263.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease MspI PXA PF02194.10 AET39264.1 - 1.5e-05 24.6 2.2 6.5e-05 22.5 0.8 2.5 2 1 0 2 2 2 1 PXA domain DUF247 PF03140.10 AET39264.1 - 0.027 13.4 0.8 1.7 7.5 0.1 2.1 1 1 0 2 2 2 0 Plant protein of unknown function DUF3168 PF11367.3 AET39264.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) CybS PF05328.7 AET39266.1 - 9.4e-47 157.9 0.0 1.1e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 CybS DUF4405 PF14358.1 AET39266.1 - 0.00043 20.3 1.1 0.00051 20.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4405) Peptidase_M16 PF00675.15 AET39267.1 - 2.4e-52 176.6 0.4 5e-52 175.6 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AET39267.1 - 2e-35 122.1 0.0 4.6e-35 120.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain MRP-S28 PF10213.4 AET39268.1 - 1.5e-47 160.8 3.7 3.1e-47 159.7 2.5 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF4158 PF13700.1 AET39268.1 - 0.034 13.6 0.6 0.065 12.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) HMG_box PF00505.14 AET39269.1 - 1.2e-11 44.6 2.2 1.2e-11 44.6 1.5 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AET39269.1 - 3.8e-08 33.5 1.8 3.8e-08 33.5 1.2 2.2 2 0 0 2 2 2 1 HMG-box domain BLVR PF06375.6 AET39269.1 - 0.0041 16.9 6.4 0.0041 16.9 4.4 1.8 1 1 1 2 2 2 1 Bovine leukaemia virus receptor (BLVR) Zip PF02535.17 AET39270.1 - 1.3e-59 201.7 10.0 1.8e-59 201.2 6.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 AET39270.1 - 2 7.7 11.7 0.06 12.6 3.2 2.1 2 2 0 2 2 2 0 HupE / UreJ protein IPK PF03770.11 AET39271.1 - 2.2e-55 187.3 1.3 2.9e-55 187.0 0.9 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase HSP20 PF00011.16 AET39272.1 - 2.6e-10 40.0 0.0 4.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Sec7 PF01369.15 AET39273.1 - 5.7e-62 208.7 0.1 1.7e-61 207.2 0.1 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 AET39273.1 - 1.7e-52 177.2 2.2 1.7e-52 177.2 1.5 4.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 AET39273.1 - 2.1e-27 94.4 3.3 6.1e-27 92.9 0.3 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) AMP-binding PF00501.23 AET39274.1 - 1.9e-88 296.6 0.1 2.4e-88 296.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AET39274.1 - 2.6e-19 69.9 1.7 2.8e-19 69.8 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Mem_trans PF03547.13 AET39275.1 - 1.3e-57 194.8 1.0 1.6e-57 194.5 0.7 1.1 1 0 0 1 1 1 1 Membrane transport protein Dicty_REP PF05086.7 AET39275.1 - 0.22 9.2 2.4 0.32 8.6 1.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NUDIX PF00293.23 AET39276.1 - 3.3e-18 65.6 0.0 6.1e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Stm1_N PF09598.5 AET39277.1 - 3.1e-19 69.4 4.1 3.1e-19 69.4 2.8 4.3 5 0 0 5 5 5 2 Stm1 PDE6_gamma PF04868.7 AET39277.1 - 7.8 6.4 7.0 1.5 8.6 1.6 2.2 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Stb3 PF10330.4 AET39278.1 - 5.3e-31 106.1 0.1 1.1e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein Nucleoplasmin PF03066.10 AET39278.1 - 0.00057 19.4 0.5 0.0009 18.7 0.4 1.4 1 0 0 1 1 1 1 Nucleoplasmin Cwf_Cwc_15 PF04889.7 AET39278.1 - 0.084 12.5 8.1 0.22 11.1 5.6 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.6 AET39278.1 - 0.24 11.2 4.9 0.8 9.4 3.4 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIA PF03153.8 AET39278.1 - 2.9 7.6 14.2 0.28 11.0 0.8 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 AET39278.1 - 4.3 6.5 8.6 7.1 5.7 6.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2415 PF10313.4 AET39279.1 - 2.5e-20 71.8 1.4 4.8e-20 70.9 1.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) CDC37_N PF03234.9 AET39280.1 - 9.7e-67 224.7 15.7 9.7e-67 224.7 10.9 3.1 2 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 AET39280.1 - 5.3e-49 166.0 4.7 5.3e-49 166.0 3.3 2.7 4 0 0 4 4 4 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 AET39280.1 - 9.3e-28 96.0 8.3 2.6e-27 94.5 4.4 2.7 2 0 0 2 2 2 1 Cdc37 C terminal domain EF-hand_2 PF09068.6 AET39280.1 - 0.33 11.0 2.8 2.9 7.9 0.1 3.1 3 1 0 3 3 3 0 EF hand TFIID_30kDa PF03540.8 AET39281.1 - 1.2e-26 92.2 0.1 2.1e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit NapB PF03892.9 AET39281.1 - 0.069 12.8 0.3 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) Formyl_trans_N PF00551.14 AET39281.1 - 0.078 12.5 0.2 0.88 9.0 0.0 2.0 2 0 0 2 2 2 0 Formyl transferase Pep3_Vps18 PF05131.9 AET39282.1 - 1e-34 119.1 0.0 2.3e-34 117.9 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 AET39282.1 - 2e-08 33.9 2.8 2e-08 33.9 2.0 4.3 2 2 3 5 5 5 1 Region in Clathrin and VPS zf-RING_5 PF14634.1 AET39282.1 - 0.00017 21.2 1.1 0.00017 21.2 0.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 AET39282.1 - 0.0002 21.1 3.7 0.00046 19.9 2.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AET39282.1 - 0.00065 19.6 1.3 0.00065 19.6 0.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 AET39282.1 - 0.0011 19.1 0.3 0.0011 19.1 0.2 2.6 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 AET39282.1 - 0.0041 16.7 1.8 0.013 15.0 1.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LSM PF01423.17 AET39283.1 - 1.2e-15 56.7 0.1 1.5e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain Tail_tube PF10618.4 AET39283.1 - 0.0023 17.6 0.1 0.013 15.1 0.0 1.9 1 1 1 2 2 2 1 Phage tail tube protein SM-ATX PF14438.1 AET39283.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain Sec5 PF15469.1 AET39284.1 - 2.2e-52 177.4 7.3 2.2e-52 177.4 5.1 3.1 5 0 0 5 5 5 1 Exocyst complex component Sec5 WD40 PF00400.27 AET39285.1 - 1.7e-05 24.5 1.6 0.036 13.9 0.2 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Translin PF01997.11 AET39286.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Translin family Glyco_hydro_81 PF03639.8 AET39287.1 - 7.1e-233 774.6 12.9 8.6e-233 774.3 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Sec1 PF00995.18 AET39288.1 - 9.1e-100 334.9 4.0 1.1e-99 334.6 2.8 1.0 1 0 0 1 1 1 1 Sec1 family ATP_bind_4 PF01902.12 AET39290.1 - 1e-34 119.8 0.0 1.2e-33 116.3 0.0 2.5 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 AET39290.1 - 1.7e-14 53.6 0.0 3.9e-09 36.2 0.0 2.9 2 1 0 2 2 2 2 Endoribonuclease L-PSP Pro_dh PF01619.13 AET39291.1 - 5.1e-57 193.2 0.0 6.6e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase SLS PF14611.1 AET39293.1 - 2.8e-28 98.7 4.3 3.4e-28 98.4 1.2 2.2 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator SAP30_Sin3_bdg PF13867.1 AET39293.1 - 0.056 13.3 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF433 PF04255.9 AET39293.1 - 0.14 11.6 0.1 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Cwf_Cwc_15 PF04889.7 AET39294.1 - 6.5e-23 81.7 8.6 8.1e-13 48.6 1.1 2.1 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein SH3_9 PF14604.1 AET39295.1 - 6.7e-15 54.4 0.1 1.4e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AET39295.1 - 2.8e-14 52.2 0.1 6.6e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AET39295.1 - 1.7e-09 37.0 0.1 3.7e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain TPR_2 PF07719.12 AET39296.1 - 9e-09 34.5 0.0 0.0086 15.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 AET39296.1 - 1.6e-08 34.0 0.1 0.0031 17.1 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 AET39296.1 - 4.7e-08 33.2 2.8 4.4e-05 23.7 0.3 3.8 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 AET39296.1 - 5.4e-08 32.1 0.4 0.013 15.0 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AET39296.1 - 8.4e-08 32.1 0.0 0.023 15.2 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 AET39296.1 - 3.3e-06 27.5 0.0 0.0029 18.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AET39296.1 - 4.6e-06 26.0 0.0 0.14 12.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AET39296.1 - 1.6e-05 24.7 0.1 0.13 12.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AET39296.1 - 4.5e-05 23.2 0.0 0.4 10.6 0.1 2.9 3 1 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AET39296.1 - 7.3e-05 22.8 0.8 0.077 13.1 0.1 3.1 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AET39296.1 - 0.00017 21.1 0.0 0.033 13.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 AET39296.1 - 0.0039 16.2 0.2 0.37 9.8 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.1 AET39296.1 - 0.021 14.0 0.2 0.56 9.2 0.1 2.1 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 AET39296.1 - 0.022 15.1 0.1 24 5.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AA_permease PF00324.16 AET39297.1 - 6.4e-73 245.7 40.4 1e-72 245.0 28.0 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET39297.1 - 4.3e-30 104.6 45.4 1.3e-29 103.0 31.5 1.7 1 1 0 1 1 1 1 Amino acid permease Na_H_Exchanger PF00999.16 AET39298.1 - 1.5e-76 257.3 24.5 1.9e-76 257.1 17.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 AET39298.1 - 8.5e-75 252.6 24.7 4.8e-73 246.8 17.1 2.0 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2407_C PF13373.1 AET39298.1 - 0.43 10.4 1.5 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 DUF2407 C-terminal domain SAC3_GANP PF03399.11 AET39299.1 - 8.1e-54 182.2 0.8 8.1e-54 182.2 0.6 2.0 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 AET39299.1 - 3.4e-17 62.3 1.5 3.4e-17 62.3 1.0 2.4 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain Methyltransf_16 PF10294.4 AET39300.1 - 3.5e-07 29.8 2.0 0.0013 18.2 0.2 2.4 1 1 1 2 2 2 2 Putative methyltransferase Enkurin PF13864.1 AET39300.1 - 0.054 13.7 0.2 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Calmodulin-binding Indigoidine_A PF04227.7 AET39300.1 - 0.093 11.9 0.0 0.77 8.9 0.0 2.0 2 0 0 2 2 2 0 Indigoidine synthase A like protein Semialdhyde_dhC PF02774.13 AET39301.1 - 3.8e-45 154.0 0.0 5.4e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 AET39301.1 - 1e-30 106.5 0.0 1.8e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 AET39301.1 - 0.037 14.5 0.1 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 AET39301.1 - 0.05 12.5 0.2 0.081 11.8 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase RNA_polI_A14 PF08203.6 AET39302.1 - 4.4e-21 74.9 0.1 1.2e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Pro_isomerase PF00160.16 AET39303.1 - 1e-47 162.2 0.1 1.1e-47 162.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rgp1 PF08737.5 AET39304.1 - 4.3e-73 246.7 7.8 4.3e-73 246.7 5.4 1.5 2 0 0 2 2 2 1 Rgp1 DUF1136 PF06582.7 AET39304.1 - 1.2 8.9 3.8 2.4 7.9 2.6 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) Avl9 PF09794.4 AET39305.1 - 2.7e-147 490.1 1.1 3.3e-147 489.8 0.8 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 AET39305.1 - 6.4e-10 38.7 0.1 0.00021 20.9 0.0 3.1 3 0 0 3 3 3 2 Stabilization of polarity axis DUF2347 PF09804.4 AET39305.1 - 1.7e-08 34.0 0.1 0.0027 17.0 0.0 2.6 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 AET39305.1 - 0.0017 18.3 2.1 0.011 15.7 0.0 2.8 2 1 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.16 AET39305.1 - 0.0018 18.0 2.3 0.19 11.3 0.6 2.9 2 1 0 2 2 2 1 DENN (AEX-3) domain efThoc1 PF11957.3 AET39306.1 - 3.5e-81 273.1 19.3 5.1e-81 272.6 13.4 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor zf-CCHC PF00098.18 AET39307.1 - 3.2e-09 36.2 9.4 8e-07 28.6 0.3 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_3 PF13014.1 AET39307.1 - 7.6e-06 25.4 0.0 7.6e-06 25.4 0.0 2.1 2 1 0 2 2 2 1 KH domain KH_1 PF00013.24 AET39307.1 - 8.3e-06 25.3 0.1 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 AET39307.1 - 0.00041 20.0 5.6 0.014 15.1 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle UPF0167 PF03691.9 AET39307.1 - 0.037 13.4 0.3 0.058 12.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) PolC_DP2 PF03833.8 AET39307.1 - 0.089 10.4 0.6 0.12 10.0 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC_4 PF14392.1 AET39307.1 - 0.13 11.9 3.4 6.6 6.4 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle HAT PF02184.11 AET39308.1 - 8.9e-18 63.7 29.8 8.7e-06 25.3 0.0 9.4 9 1 0 9 9 9 4 HAT (Half-A-TPR) repeat Suf PF05843.9 AET39308.1 - 1.4e-13 51.2 23.2 0.0011 18.7 0.0 7.3 2 2 3 6 6 6 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 AET39308.1 - 4.1e-13 48.6 0.0 0.046 14.3 0.0 8.0 3 2 6 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 AET39308.1 - 4.8e-08 33.4 0.3 0.026 15.2 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 AET39308.1 - 8.2e-06 26.0 0.0 0.1 12.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AET39308.1 - 0.0013 18.4 3.7 28 4.9 0.0 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 AET39308.1 - 0.007 16.0 1.7 0.007 16.0 1.2 5.7 5 3 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_17 PF13431.1 AET39308.1 - 0.0092 16.1 0.8 0.19 12.0 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AET39308.1 - 0.095 12.6 7.4 4.6 7.2 0.1 4.6 6 1 0 6 6 6 0 Tetratricopeptide repeat Merozoite_SPAM PF07133.6 AET39308.1 - 2.4 8.0 15.4 0.031 14.1 5.2 1.8 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) ubiquitin PF00240.18 AET39309.1 - 6e-17 60.7 0.1 6.6e-17 60.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AET39309.1 - 1.8e-10 40.3 0.0 1.9e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AET39309.1 - 0.013 15.7 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Methyltransf_26 PF13659.1 AET39310.1 - 3.1e-12 46.5 0.0 4.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AET39310.1 - 5.4e-07 29.1 0.0 6.6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AET39310.1 - 0.00083 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 AET39310.1 - 0.0028 17.2 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 AET39310.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.8 AET39310.1 - 0.06 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 AET39310.1 - 0.15 12.6 0.0 0.35 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Dopey_N PF04118.9 AET39311.1 - 1.2e-117 392.0 1.5 1.2e-117 392.0 1.0 3.4 4 0 0 4 4 4 2 Dopey, N-terminal Abhydrolase_2 PF02230.11 AET39312.1 - 2.1e-55 187.5 0.0 2.3e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AET39312.1 - 6.9e-12 45.3 0.0 9.9e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 AET39312.1 - 3.6e-09 36.3 0.0 7.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AET39312.1 - 1.6e-07 31.4 0.0 2.7e-06 27.4 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 AET39312.1 - 9e-07 28.3 0.0 1.1e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 AET39312.1 - 0.0026 16.9 0.0 0.28 10.3 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 AET39312.1 - 0.007 15.9 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 AET39312.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Mod_r PF07200.8 AET39313.1 - 5e-18 65.4 9.7 6.4e-18 65.1 6.7 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Takusan PF04822.8 AET39313.1 - 0.048 13.4 4.8 0.43 10.3 0.7 2.4 1 1 1 2 2 2 0 Takusan DUF4559 PF15112.1 AET39313.1 - 0.052 12.7 4.7 0.062 12.4 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) MalF_P2 PF14785.1 AET39313.1 - 0.27 11.0 2.1 0.48 10.2 0.4 2.0 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain DUF342 PF03961.8 AET39313.1 - 0.32 9.3 4.0 0.31 9.3 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4527 PF15030.1 AET39313.1 - 0.43 9.8 3.4 0.32 10.2 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) WD40 PF00400.27 AET39314.1 - 1.2e-25 88.3 10.9 4.8e-07 29.4 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-RING_2 PF13639.1 AET39315.1 - 2.9e-11 43.0 8.5 6.3e-10 38.7 3.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 AET39315.1 - 3.7e-08 33.3 4.2 9.3e-07 28.8 1.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AET39315.1 - 1.9e-05 24.5 9.3 0.00016 21.6 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AET39315.1 - 6.2e-05 22.5 5.8 8.9e-05 22.0 2.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AET39315.1 - 0.0001 21.9 7.9 0.00012 21.7 3.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AET39315.1 - 0.00023 20.7 0.7 0.00023 20.7 0.5 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AET39315.1 - 0.00027 20.7 3.8 0.00027 20.7 2.6 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AET39315.1 - 0.00061 19.4 7.1 0.0024 17.5 2.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 AET39315.1 - 0.0059 16.1 2.9 0.016 14.7 2.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 AET39315.1 - 0.018 14.8 3.2 0.037 13.8 0.6 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.1 AET39315.1 - 0.16 11.7 1.0 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-Nse PF11789.3 AET39315.1 - 0.65 9.5 3.1 1.4 8.5 2.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 AET39315.1 - 1.8 8.2 8.2 1.5 8.4 2.5 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Asp PF00026.18 AET39316.1 - 1.7e-70 237.8 0.5 2.1e-70 237.4 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AET39316.1 - 3.7e-11 43.2 0.0 1.8e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AET39316.1 - 0.0031 17.9 0.5 16 6.0 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 AET39316.1 - 0.023 14.4 0.1 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 AET39316.1 - 0.025 14.1 0.0 0.19 11.2 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal RPA_C PF08784.6 AET39317.1 - 0.072 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal Cullin_binding PF03556.10 AET39318.1 - 6.4e-31 106.9 3.9 6.4e-31 106.9 2.7 1.9 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 AET39318.1 - 1.8e-08 33.7 0.0 3.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DSPn PF14671.1 AET39318.1 - 0.061 13.3 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half TFIID_20kDa PF03847.8 AET39319.1 - 2.7e-32 110.8 2.4 3.2e-32 110.6 0.4 2.0 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 AET39319.1 - 0.0019 18.2 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AET39319.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone THOC7 PF05615.8 AET39319.1 - 3.2 8.0 13.8 2.2 8.5 7.8 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 FHIPEP PF00771.15 AET39319.1 - 4.3 5.5 9.0 6.6 4.9 6.3 1.2 1 0 0 1 1 1 0 FHIPEP family WD40 PF00400.27 AET39320.1 - 1.5e-74 243.4 29.1 1.6e-09 37.2 0.2 12.2 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 AET39320.1 - 1.1e-21 76.7 0.3 2.6e-21 75.5 0.2 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 AET39320.1 - 1.4e-08 33.3 8.2 0.00022 19.5 0.1 5.7 5 2 0 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 AET39320.1 - 9e-05 22.2 4.4 5.6 6.6 0.0 5.4 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 AET39320.1 - 0.062 12.5 12.1 3.4 6.8 0.0 5.3 6 0 0 6 6 6 0 TUP1-like enhancer of split HVSL PF09749.4 AET39321.1 - 1.1e-27 96.5 2.8 1.4e-27 96.3 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Choline_kinase PF01633.15 AET39322.1 - 2.7e-61 206.7 0.0 3.8e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 AET39322.1 - 3.9e-13 48.6 0.6 1.1e-12 47.2 0.1 1.9 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 AET39322.1 - 6.1e-10 39.2 0.0 0.0003 20.6 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 AET39322.1 - 0.16 11.1 0.5 5.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase UBA_e1_thiolCys PF10585.4 AET39322.1 - 0.35 10.2 2.6 0.6 9.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site 2-oxoacid_dh PF00198.18 AET39323.1 - 2e-78 262.8 0.1 2.6e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AET39323.1 - 5.7e-16 57.9 0.2 1e-15 57.0 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 AET39323.1 - 5.2e-06 25.8 0.4 0.00051 19.2 0.0 2.1 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 AET39323.1 - 6e-05 22.6 0.1 0.0012 18.4 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 AET39323.1 - 0.0001 22.5 0.4 0.003 17.8 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 AET39323.1 - 0.00028 20.5 0.1 0.00059 19.5 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD PF00529.15 AET39323.1 - 0.0066 15.7 1.2 0.075 12.3 0.3 2.5 1 1 2 3 3 3 1 HlyD family secretion protein RnfC_N PF13375.1 AET39323.1 - 0.01 15.5 0.0 0.033 13.8 0.0 1.9 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Slx4 PF09494.5 AET39324.1 - 9.2e-12 44.5 0.1 2.8e-11 42.9 0.1 1.9 1 0 0 1 1 1 1 Slx4 endonuclease Fib_alpha PF08702.5 AET39324.1 - 0.21 11.7 7.0 0.47 10.5 0.5 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mcp5_PH PF12814.2 AET39325.1 - 8e-38 129.1 0.0 2.7e-37 127.4 0.0 2.0 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology HALZ PF02183.13 AET39325.1 - 0.00035 20.2 1.7 0.00035 20.2 1.2 6.8 7 0 0 7 7 7 1 Homeobox associated leucine zipper DUF972 PF06156.8 AET39325.1 - 0.12 12.7 23.5 0.22 11.8 1.9 4.4 2 1 0 3 3 3 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 AET39325.1 - 0.65 9.9 25.2 0.032 14.1 2.2 5.4 3 0 0 3 3 3 0 bZIP transcription factor zf-CCCH PF00642.19 AET39326.1 - 4e-19 67.8 18.5 2.1e-10 40.0 1.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AET39326.1 - 0.28 11.2 12.3 0.51 10.4 0.5 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type RWD PF05773.17 AET39327.1 - 4.5e-22 78.0 4.3 9.8e-22 76.9 3.0 1.6 1 1 0 1 1 1 1 RWD domain ENTH PF01417.15 AET39328.1 - 4e-30 104.2 0.5 6.7e-30 103.5 0.3 1.4 1 0 0 1 1 1 1 ENTH domain DSS1_SEM1 PF05160.8 AET39328.1 - 0.0088 15.7 0.7 4.9 7.0 0.1 2.5 2 0 0 2 2 2 2 DSS1/SEM1 family ABC_membrane PF00664.18 AET39329.1 - 2.1e-89 299.5 48.8 1e-49 169.4 8.3 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 AET39329.1 - 5.6e-48 162.7 0.0 1.9e-28 99.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 AET39329.1 - 6.7e-10 38.5 5.5 0.0005 19.3 0.1 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AET39329.1 - 1.7e-06 28.1 0.3 0.065 13.2 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 AET39329.1 - 9.5e-06 25.7 0.2 1.2 9.0 0.0 4.7 2 2 0 3 3 3 2 AAA domain AAA_25 PF13481.1 AET39329.1 - 1.1e-05 24.9 0.1 0.12 11.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 AET39329.1 - 2.5e-05 24.7 0.3 0.17 12.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 AET39329.1 - 4.3e-05 23.4 0.0 0.33 10.9 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 AET39329.1 - 0.00011 21.6 0.1 0.37 10.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AET39329.1 - 0.00015 21.0 0.0 0.1 11.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 AET39329.1 - 0.00016 21.2 1.6 1.1 8.6 0.0 3.6 3 1 1 4 4 4 2 AAA-like domain DUF87 PF01935.12 AET39329.1 - 0.011 15.5 4.5 0.047 13.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 AET39329.1 - 0.032 13.9 0.4 8.6 6.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 AET39329.1 - 0.035 14.4 0.2 0.035 14.4 0.1 3.3 4 1 0 4 4 3 0 AAA domain AAA_22 PF13401.1 AET39329.1 - 0.044 13.9 0.9 4.7 7.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 AET39329.1 - 0.076 11.7 0.0 12 4.6 0.0 2.3 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 AET39329.1 - 0.15 11.5 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 AET39329.1 - 0.17 12.7 0.1 3.5 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AET39329.1 - 0.24 10.9 0.5 36 3.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 AET39329.1 - 2.5 7.8 6.2 2.1 8.1 0.1 2.9 3 0 0 3 3 3 0 Dynamin family Pkinase PF00069.20 AET39330.1 - 4.4e-70 235.8 0.2 9e-70 234.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39330.1 - 4.3e-31 107.9 0.0 7.9e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AET39330.1 - 4.9e-05 22.4 0.1 0.00019 20.5 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET39330.1 - 0.00067 19.4 5.6 0.0015 18.3 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AET39330.1 - 0.0016 17.4 0.0 0.12 11.3 0.0 2.3 1 1 0 2 2 2 1 Kinase-like eIF-3_zeta PF05091.7 AET39330.1 - 0.16 10.5 9.6 0.21 10.2 6.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rtf2 PF04641.7 AET39330.1 - 0.49 9.5 11.5 0.9 8.6 7.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4175 PF13779.1 AET39330.1 - 1.7 6.2 30.2 2.2 5.8 21.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.1 AET39330.1 - 4.5 6.1 10.4 6.3 5.6 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDRGK PF09756.4 AET39330.1 - 7.3 5.9 16.2 11 5.3 11.2 1.2 1 0 0 1 1 1 0 DDRGK domain Med19 PF10278.4 AET39330.1 - 7.8 6.1 10.3 13 5.3 7.1 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Zip PF02535.17 AET39330.1 - 8 5.3 6.4 11 4.8 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Flocculin_t3 PF13928.1 AET39333.1 - 2.5e-10 40.3 17.2 2.5e-10 40.3 11.9 2.4 3 0 0 3 3 3 1 Flocculin type 3 repeat BTB_2 PF02214.17 AET39334.1 - 3.7e-08 33.4 0.0 0.00059 19.9 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain RNase_T PF00929.19 AET39336.1 - 1.6e-16 61.0 0.5 3.6e-16 59.8 0.0 1.8 2 1 1 3 3 3 1 Exonuclease DNA_pol_A_exo1 PF01612.15 AET39336.1 - 0.021 14.3 0.2 0.27 10.6 0.1 2.7 2 1 0 2 2 2 0 3'-5' exonuclease CHORD PF04968.7 AET39336.1 - 0.035 14.3 3.8 0.076 13.2 2.7 1.6 1 0 0 1 1 1 0 CHORD AAA_5 PF07728.9 AET39337.1 - 3.2e-126 415.7 1.4 8.8e-22 77.3 0.0 10.1 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AET39337.1 - 3.4e-31 107.5 0.0 6.8e-10 38.6 0.0 7.7 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 AET39337.1 - 2.2e-29 102.3 0.4 0.00038 20.6 0.0 7.4 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AET39337.1 - 5.7e-21 75.5 7.8 0.024 15.4 0.0 8.4 8 0 0 8 8 6 6 AAA domain Sigma54_activ_2 PF14532.1 AET39337.1 - 8.1e-20 71.2 2.2 0.00016 21.7 0.0 7.6 7 0 0 7 7 7 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 AET39337.1 - 1.1e-19 70.4 1.1 0.0023 17.4 0.1 6.4 7 0 0 7 7 6 5 Sigma-54 interaction domain AAA_14 PF13173.1 AET39337.1 - 7.4e-19 67.9 0.9 0.0028 17.5 0.0 9.8 9 1 1 10 10 10 3 AAA domain AAA_22 PF13401.1 AET39337.1 - 6.1e-18 65.2 0.9 0.041 14.0 0.0 8.3 7 0 0 7 7 7 3 AAA domain AAA_16 PF13191.1 AET39337.1 - 4.5e-17 62.6 4.6 0.0058 16.6 0.1 7.8 6 2 0 6 6 6 4 AAA ATPase domain AAA_30 PF13604.1 AET39337.1 - 3.3e-15 56.1 0.0 0.23 11.0 0.1 8.2 8 0 0 8 8 7 2 AAA domain T2SE PF00437.15 AET39337.1 - 3.4e-15 55.6 2.6 0.074 11.9 0.0 6.3 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_33 PF13671.1 AET39337.1 - 7.5e-15 55.0 0.0 0.22 11.4 0.0 7.5 7 1 0 7 7 7 3 AAA domain UPF0079 PF02367.12 AET39337.1 - 8.1e-14 51.3 3.5 0.25 10.9 0.0 7.3 7 0 0 7 7 6 3 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 AET39337.1 - 8.2e-13 47.9 7.1 0.89 8.6 0.0 8.7 9 0 0 9 9 9 4 Zeta toxin Miro PF08477.8 AET39337.1 - 1.2e-12 48.3 1.9 0.83 10.1 0.0 7.0 6 0 0 6 6 6 3 Miro-like protein AAA_19 PF13245.1 AET39337.1 - 4.6e-12 45.5 1.0 0.038 13.7 0.2 6.2 6 0 0 6 6 6 3 Part of AAA domain PduV-EutP PF10662.4 AET39337.1 - 3.4e-11 42.8 1.2 0.017 14.5 0.1 6.5 7 0 0 7 7 6 2 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 AET39337.1 - 4.2e-11 43.2 19.9 0.00048 20.4 0.0 7.4 8 0 0 8 8 6 3 ABC transporter DUF258 PF03193.11 AET39337.1 - 4.9e-11 42.0 6.3 0.25 10.5 0.1 6.2 6 0 0 6 6 6 4 Protein of unknown function, DUF258 RNA_helicase PF00910.17 AET39337.1 - 5.7e-11 42.5 2.5 0.64 10.2 0.0 7.7 7 0 0 7 7 6 2 RNA helicase MobB PF03205.9 AET39337.1 - 2.2e-10 40.3 6.7 0.61 9.7 0.1 6.6 6 0 0 6 6 6 3 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 AET39337.1 - 2.5e-09 37.3 4.1 1.6 8.6 0.0 7.5 7 0 0 7 7 7 1 AAA domain AAA_7 PF12775.2 AET39337.1 - 5.3e-09 35.5 4.9 0.027 13.5 0.1 5.3 5 0 0 5 5 5 2 P-loop containing dynein motor region D3 Mg_chelatase PF01078.16 AET39337.1 - 5.5e-09 35.4 5.6 3.5 6.7 0.1 8.5 9 1 1 10 10 10 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 AET39337.1 - 6.2e-09 35.8 0.2 6.9 6.6 0.0 6.7 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_29 PF13555.1 AET39337.1 - 9.6e-09 34.6 0.2 1 8.9 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain NACHT PF05729.7 AET39337.1 - 2.2e-08 33.9 5.2 0.28 10.8 0.0 6.2 6 0 0 6 6 4 2 NACHT domain RuvB_N PF05496.7 AET39337.1 - 8.8e-08 31.4 3.6 0.079 11.9 0.0 5.8 7 0 0 7 7 7 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AET39337.1 - 1.5e-06 27.7 0.2 1.6 8.0 0.0 5.2 5 0 0 5 5 5 2 AAA domain PhoH PF02562.11 AET39337.1 - 2.3e-05 23.7 1.4 4 6.5 0.0 4.9 5 0 0 5 5 5 1 PhoH-like protein ATP-synt_ab PF00006.20 AET39337.1 - 4e-05 23.2 0.0 0.91 8.9 0.0 4.0 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 AET39337.1 - 5.3e-05 23.5 49.5 0.028 14.7 0.0 10.3 10 2 0 10 10 6 4 AAA domain SRP54 PF00448.17 AET39337.1 - 0.0017 17.8 13.9 1.2 8.5 0.1 6.2 7 0 0 7 7 6 2 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 AET39337.1 - 0.012 15.1 4.1 12 5.2 0.0 4.4 4 0 0 4 4 4 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 AET39337.1 - 0.037 13.7 12.8 4.4 7.0 0.1 6.1 7 0 0 7 7 5 0 NTPase ArgK PF03308.11 AET39337.1 - 2.4 6.8 3.3 25 3.5 0.1 3.2 4 0 0 4 4 3 0 ArgK protein tRNA_int_endo PF01974.12 AET39338.1 - 1e-20 73.2 0.7 2.4e-20 72.1 0.2 1.8 1 1 1 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 AET39338.1 - 0.00093 18.6 0.0 0.76 9.3 0.0 2.6 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain CDC45 PF02724.9 AET39340.1 - 1.6e-201 670.5 0.0 2e-201 670.2 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Apc9 PF12856.2 AET39341.1 - 3.9e-15 55.7 0.8 6.9e-15 54.9 0.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 9 CH PF00307.26 AET39342.1 - 4.9e-72 238.8 0.7 2.1e-20 72.7 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 AET39342.1 - 2.1e-05 24.1 0.0 0.9 9.2 0.0 4.3 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.1 AET39342.1 - 0.0006 19.8 0.7 0.0043 17.1 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AET39342.1 - 0.029 13.6 2.3 5.5 6.5 0.0 3.7 2 1 2 4 4 4 0 EF hand adh_short PF00106.20 AET39343.1 - 0.0025 17.7 0.0 0.13 12.2 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase DUF3796 PF12676.2 AET39343.1 - 2.7 8.2 9.4 0.62 10.2 3.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) WD40 PF00400.27 AET39344.1 - 4.6e-14 51.6 21.0 7.2e-05 22.5 0.1 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat RWD PF05773.17 AET39344.1 - 1.8e-05 24.5 0.0 4.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain zf-rbx1 PF12678.2 AET39344.1 - 0.00083 19.4 4.9 0.0023 17.9 3.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger OrfB_Zn_ribbon PF07282.6 AET39344.1 - 0.0011 18.6 1.8 0.0025 17.4 1.2 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-RING_2 PF13639.1 AET39344.1 - 0.016 15.0 7.1 0.041 13.7 4.9 1.7 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.17 AET39344.1 - 0.09 12.5 7.1 0.21 11.3 4.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 AET39344.1 - 0.15 11.8 5.6 0.27 10.9 3.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 AET39344.1 - 0.22 11.4 6.5 0.64 9.9 4.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 AET39344.1 - 0.36 10.8 10.4 0.9 9.6 7.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-DHHC PF01529.15 AET39345.1 - 2.1e-26 92.3 14.6 2.1e-26 92.3 10.1 2.5 2 1 0 2 2 2 2 DHHC palmitoyltransferase Abhydrolase_6 PF12697.2 AET39348.1 - 1.9e-21 77.0 0.0 3.1e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET39348.1 - 3.7e-12 46.2 0.0 4.4e-11 42.7 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AET39348.1 - 3.9e-11 42.9 0.0 6.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 AET39348.1 - 0.00046 19.3 0.0 0.065 12.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 AET39348.1 - 0.005 16.3 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 AET39348.1 - 0.006 15.0 0.0 0.035 12.5 0.0 1.9 2 0 0 2 2 2 1 Ndr family Thioesterase PF00975.15 AET39348.1 - 0.0075 16.5 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF2305 PF10230.4 AET39348.1 - 0.014 14.8 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 AET39348.1 - 0.038 13.5 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Fungal_trans PF04082.13 AET39349.1 - 2.5e-34 118.3 1.9 2.5e-34 118.3 1.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET39349.1 - 2.6e-09 36.8 9.3 4.8e-09 35.9 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2841 PF11001.3 AET39350.1 - 2.1e-37 127.7 2.7 4.6e-37 126.6 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) F-box-like PF12937.2 AET39351.1 - 0.00045 19.8 0.1 0.0015 18.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like TPR_1 PF00515.23 AET39351.1 - 0.00088 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 AET39351.1 - 0.0015 18.2 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 AET39351.1 - 0.002 17.7 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 TPR repeat MIT PF04212.13 AET39351.1 - 0.074 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 AET39354.1 - 5e-72 242.1 0.6 1.7e-71 240.4 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39354.1 - 3.2e-39 134.5 0.3 1.8e-37 128.8 0.0 2.3 1 1 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.14 AET39354.1 - 9.7e-20 69.7 0.0 1.9e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 AET39354.1 - 5.7e-06 25.5 0.0 9.9e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AET39354.1 - 0.00011 21.3 0.0 0.00021 20.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET39354.1 - 0.0038 16.9 0.0 0.023 14.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 AET39354.1 - 0.011 15.0 0.1 0.019 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 AET39354.1 - 0.12 11.6 0.8 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PHD PF00628.24 AET39355.1 - 0.017 14.7 3.7 0.049 13.3 2.5 1.8 1 0 0 1 1 1 0 PHD-finger SurE PF01975.12 AET39356.1 - 0.089 12.0 2.1 3.4 6.9 0.5 2.3 2 0 0 2 2 2 0 Survival protein SurE Nyv1_N PF09426.5 AET39357.1 - 2.2e-54 182.8 1.1 3.3e-54 182.2 0.8 1.3 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.16 AET39357.1 - 7.3e-27 92.8 3.4 1.2e-26 92.1 2.4 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF2077 PF09850.4 AET39357.1 - 0.0037 16.6 0.2 0.037 13.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2077) DUF2158 PF09926.4 AET39357.1 - 0.0072 15.7 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2158) EMP24_GP25L PF01105.19 AET39357.1 - 0.84 9.3 9.8 6.1 6.5 6.8 2.1 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CBFD_NFYB_HMF PF00808.18 AET39358.1 - 3.7e-06 26.8 0.4 6.9e-06 26.0 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AET39358.1 - 0.063 13.4 0.1 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TRM PF02005.11 AET39359.1 - 2.4e-135 451.2 0.0 2.9e-135 451.0 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 AET39359.1 - 3.3e-05 23.5 0.0 6.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DUF2197 PF09963.4 AET39359.1 - 0.028 14.3 0.1 0.067 13.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) Cons_hypoth95 PF03602.10 AET39359.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.11 AET39361.1 - 7.2e-41 140.0 44.6 5.4e-40 137.1 30.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AET39361.1 - 6.4e-15 54.6 19.7 6.4e-15 54.6 13.6 3.8 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 AET39361.1 - 0.0035 15.5 3.6 0.007 14.5 2.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Sulfate_transp PF00916.15 AET39362.1 - 5e-77 258.6 9.1 5e-77 258.6 6.3 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AET39362.1 - 1.3e-31 108.0 1.9 1.3e-31 108.0 1.3 2.2 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AET39362.1 - 0.0059 16.0 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 AET39362.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 STAS domain Apc4 PF12896.2 AET39363.1 - 1.6e-33 115.8 2.4 2.3e-33 115.2 1.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 IncA PF04156.9 AET39363.1 - 1.4 8.4 6.3 2.8 7.5 4.3 1.4 1 0 0 1 1 1 0 IncA protein SUI1 PF01253.17 AET39364.1 - 2.6e-14 52.7 0.0 8.8e-14 51.0 0.0 2.0 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.13 AET39364.1 - 0.0015 18.1 0.1 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 SWIB/MDM2 domain Kin17_mid PF10357.4 AET39364.1 - 0.016 14.8 0.3 0.041 13.5 0.2 1.6 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Ribosomal_L1 PF00687.16 AET39365.1 - 1.4e-25 89.9 0.1 1.8e-25 89.5 0.1 1.2 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Phytochelatin PF05023.9 AET39365.1 - 0.041 12.8 0.0 4.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Phytochelatin synthase RhoGEF PF00621.15 AET39365.1 - 0.12 12.2 0.8 0.44 10.4 0.3 1.9 2 0 0 2 2 2 0 RhoGEF domain Ribosomal_L34 PF00468.12 AET39366.1 - 1e-17 63.5 7.6 1e-17 63.5 5.3 1.8 1 1 1 2 2 2 1 Ribosomal protein L34 DUF2418 PF10332.4 AET39366.1 - 0.0054 17.0 0.2 0.0068 16.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Securin PF04856.8 AET39368.1 - 7.1e-30 104.4 5.9 9.9e-30 103.9 4.1 1.1 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor DnaJ PF00226.26 AET39369.1 - 2.3e-24 84.8 1.9 4e-24 84.1 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AET39369.1 - 3.9e-21 74.7 0.0 8e-19 67.3 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AET39369.1 - 3.7e-11 42.9 11.7 1.1e-10 41.4 8.3 1.7 1 1 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 AET39369.1 - 0.051 13.9 2.2 0.13 12.6 1.5 1.7 1 0 0 1 1 1 0 Cytochrome c3 Aminotran_1_2 PF00155.16 AET39370.1 - 1.8e-38 132.4 0.0 2.7e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AET39370.1 - 0.0015 17.7 0.0 0.0032 16.6 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Gaa1 PF04114.9 AET39372.1 - 2.2e-112 376.3 18.2 6.5e-107 358.3 4.4 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component SMC_N PF02463.14 AET39374.1 - 3.5e-73 245.4 40.1 7.2e-41 139.8 0.9 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AET39374.1 - 7.8e-28 96.8 0.1 3e-27 94.9 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AET39374.1 - 6.8e-11 42.6 6.1 1.1e-06 28.8 0.5 4.4 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 AET39374.1 - 4.1e-05 23.0 0.0 9.3e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Seryl_tRNA_N PF02403.17 AET39374.1 - 0.0088 16.0 12.7 0.0088 16.0 8.8 8.1 3 3 7 10 10 10 1 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 AET39374.1 - 1.1 8.3 39.8 0.024 13.8 3.5 4.9 2 2 4 6 6 6 0 Reovirus sigma C capsid protein Leucyl-specific PF14795.1 AET39374.1 - 9.3 6.2 10.6 5.7 6.8 0.2 4.7 4 0 0 4 4 4 0 Leucine-tRNA synthetase-specific domain Actin PF00022.14 AET39375.1 - 8.6e-54 182.4 0.0 1.1e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Actin FGGY_C PF02782.11 AET39376.1 - 3.1e-43 147.7 0.0 4.6e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AET39376.1 - 2.7e-25 89.1 0.3 1.7e-24 86.4 0.0 2.4 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 AET39376.1 - 0.014 14.6 0.0 0.058 12.7 0.0 1.9 2 0 0 2 2 2 0 Hexokinase UPF0075 PF03702.9 AET39376.1 - 0.11 11.3 0.1 0.25 10.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) GCR1_C PF12550.3 AET39377.1 - 3.2e-11 42.9 0.2 6.9e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Rax2 PF12768.2 AET39378.1 - 8.2e-60 202.3 8.7 1.2e-59 201.8 0.2 3.6 3 1 0 3 3 3 2 Cortical protein marker for cell polarity TRAPPC-Trs85 PF12739.2 AET39379.1 - 6.8e-85 285.2 0.1 9.1e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EMP70 PF02990.11 AET39380.1 - 3e-174 580.3 18.8 3.8e-174 580.0 13.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Ribonuc_red_lgC PF02867.10 AET39381.1 - 4.1e-215 715.4 0.0 5.5e-215 714.9 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AET39381.1 - 2.7e-24 84.7 0.4 7.9e-24 83.2 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AET39381.1 - 8.9e-16 58.1 0.6 4.5e-15 55.8 0.1 2.5 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 AET39381.1 - 0.0012 16.9 0.0 0.002 16.3 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Fis1_TPR_C PF14853.1 AET39382.1 - 5.7e-21 74.1 1.0 9.9e-21 73.3 0.7 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 AET39382.1 - 4.3e-17 61.1 0.1 1.7e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.1 AET39382.1 - 0.0069 16.6 0.2 0.036 14.3 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Aldo_ket_red PF00248.16 AET39382.1 - 0.095 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family QLQ PF08880.6 AET39382.1 - 0.14 11.5 0.2 0.6 9.5 0.0 2.0 2 0 0 2 2 2 0 QLQ Methyltransf_31 PF13847.1 AET39383.1 - 2.1e-21 76.1 0.0 3.7e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET39383.1 - 3.2e-17 63.0 0.0 5.1e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AET39383.1 - 1.8e-10 41.1 0.0 2.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AET39383.1 - 2.5e-09 37.5 0.1 4.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET39383.1 - 5.3e-07 29.6 0.0 9.4e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET39383.1 - 6.2e-07 29.7 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AET39383.1 - 1.8e-06 27.8 0.0 3.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AET39383.1 - 3.3e-06 26.8 0.0 9.5e-06 25.3 0.0 1.6 1 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 AET39383.1 - 2.3e-05 24.0 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 AET39383.1 - 0.00014 21.2 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 AET39383.1 - 0.00019 20.8 0.2 0.00035 19.9 0.1 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.15 AET39383.1 - 0.00021 20.4 0.4 0.00031 19.9 0.2 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 AET39383.1 - 0.028 13.6 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Pox_MCEL PF03291.11 AET39383.1 - 0.028 13.2 0.1 0.21 10.4 0.0 2.0 1 1 1 2 2 2 0 mRNA capping enzyme Methyltransf_9 PF08003.6 AET39383.1 - 0.045 12.4 0.0 0.061 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.7 AET39383.1 - 0.047 13.0 0.1 0.08 12.3 0.1 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 AET39383.1 - 0.05 12.7 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 AET39383.1 - 0.081 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 AET39383.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF1797 PF08796.5 AET39383.1 - 0.21 11.5 2.7 1.1 9.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) Ran_BP1 PF00638.13 AET39384.1 - 5.7e-30 103.8 0.0 1.2e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain P16-Arc PF04699.9 AET39385.1 - 1.8e-49 167.6 0.0 1.9e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Sigma70_r4 PF04545.11 AET39385.1 - 0.096 12.0 0.1 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 DUF619 PF04768.8 AET39386.1 - 3.5e-50 169.7 0.0 7.4e-50 168.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 AET39386.1 - 8.5e-29 100.3 0.0 1.7e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 AET39386.1 - 3.4e-17 62.8 0.0 5.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 AET39386.1 - 9.8e-08 32.0 0.0 2.6e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 AET39386.1 - 0.0035 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus AAA_17 PF13207.1 AET39386.1 - 0.22 12.3 0.0 0.22 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain U1snRNP70_N PF12220.3 AET39387.1 - 1.7e-19 69.9 2.5 3.3e-19 68.9 1.7 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 AET39387.1 - 1.3e-15 56.7 0.1 2.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET39387.1 - 1.9e-14 53.3 0.0 3.6e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET39387.1 - 7.9e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.1 AET39388.1 - 9.2e-20 69.9 13.3 1.8e-19 69.0 9.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 AET39388.1 - 5.2e-09 35.8 0.2 1.1e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET39388.1 - 1.2e-08 34.4 0.0 2.9e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 AET39388.1 - 2.4e-06 27.3 3.7 5.3e-06 26.2 2.5 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_6 PF14259.1 AET39388.1 - 6.7e-06 26.0 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 AET39388.1 - 6.8e-06 25.6 7.0 6.8e-06 25.6 4.9 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 AET39388.1 - 0.00012 21.4 1.0 0.00012 21.4 0.7 2.2 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 AET39388.1 - 0.0007 19.3 8.5 0.0018 18.0 5.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AET39388.1 - 0.004 16.7 10.8 0.009 15.6 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.3 AET39388.1 - 0.0072 15.6 0.1 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated zf-UDP PF14569.1 AET39388.1 - 0.039 13.7 3.9 0.11 12.2 2.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Peptidase_S49_N PF08496.5 AET39388.1 - 0.27 10.9 10.0 0.075 12.8 0.3 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-RING_5 PF14634.1 AET39388.1 - 0.31 10.8 9.6 0.69 9.6 6.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AET39388.1 - 0.55 10.1 10.0 2.5 8.0 7.0 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2578 PF10843.3 AET39389.1 - 2.4e-62 210.1 16.6 3e-62 209.7 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) Cas_Cas6 PF01881.11 AET39389.1 - 3.5 7.8 7.2 0.32 11.1 1.4 1.7 1 1 1 2 2 2 0 CRISPR associated protein Cas6 ICL PF00463.16 AET39390.1 - 2.7e-265 880.5 0.2 3.2e-265 880.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 AET39390.1 - 7.4e-11 41.7 0.7 3.8e-10 39.4 0.0 2.3 2 1 1 3 3 3 1 Phosphoenolpyruvate phosphomutase Vhr1 PF04001.8 AET39391.1 - 2.2e-49 165.3 3.1 3e-49 164.8 1.2 2.0 2 0 0 2 2 2 1 Transcription factor Vhr1 LRV_FeS PF05484.6 AET39391.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster Macoilin PF09726.4 AET39392.1 - 0.97 7.6 3.8 1.3 7.2 2.6 1.1 1 0 0 1 1 1 0 Transmembrane protein RIC3 PF15361.1 AET39392.1 - 6.9 6.8 7.9 1.3 9.2 0.9 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 SAP PF02037.22 AET39393.1 - 1e-14 53.5 0.3 3.5e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 SAP domain UbiD PF01977.11 AET39393.1 - 0.015 13.7 0.1 0.021 13.3 0.1 1.2 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase PASTA PF03793.14 AET39393.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 PASTA domain HAD_2 PF13419.1 AET39394.1 - 2.2e-12 47.5 0.0 3.1e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AET39394.1 - 7.6e-08 31.9 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AET39394.1 - 1.1e-06 29.2 0.0 8e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.21 AET39394.1 - 0.038 13.5 0.2 0.094 12.2 0.1 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HAD PF12710.2 AET39394.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ketoacyl-synt PF00109.21 AET39395.1 - 1.4e-47 162.3 0.0 1.9e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AET39395.1 - 3.5e-29 101.0 0.2 5.9e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 AET39395.1 - 0.013 14.4 0.0 0.029 13.3 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Steroid_dh PF02544.11 AET39396.1 - 8.2e-14 51.6 1.7 8.2e-14 51.6 1.2 2.0 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Transp_cyt_pur PF02133.10 AET39397.1 - 6e-79 265.6 40.9 7.3e-79 265.3 28.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cyclin PF08613.6 AET39398.1 - 1.2e-44 152.3 1.7 1.7e-44 151.8 1.2 1.3 1 0 0 1 1 1 1 Cyclin Sugar_tr PF00083.19 AET39399.1 - 0.02 13.4 0.0 0.023 13.3 0.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Peptidase_M29 PF02073.10 AET39399.1 - 0.074 11.8 0.3 0.09 11.5 0.2 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Asp-B-Hydro_N PF05279.6 AET39399.1 - 0.09 12.6 5.1 0.1 12.4 3.5 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L34e PF01199.13 AET39400.1 - 6.5e-37 125.6 4.1 6.5e-37 125.6 2.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.4 AET39400.1 - 0.39 10.9 0.1 0.39 10.9 0.1 2.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III zf-3CxxC PF13695.1 AET39400.1 - 1.5 9.0 5.6 3.7 7.8 3.9 1.8 1 1 0 1 1 1 0 Zinc-binding domain E1-E2_ATPase PF00122.15 AET39401.1 - 1.2e-25 89.8 0.0 1.2e-25 89.8 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AET39401.1 - 2.2e-12 47.8 0.0 5.5e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AET39401.1 - 3.7e-09 37.0 0.3 1.3e-08 35.2 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AET39401.1 - 1.1e-08 34.8 0.0 4.8e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AET39401.1 - 0.0064 16.0 0.0 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EXS PF03124.9 AET39402.1 - 1.2e-85 287.6 32.9 1.9e-85 286.9 22.8 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.14 AET39402.1 - 1.9e-38 132.8 3.9 4.9e-38 131.4 2.7 1.7 1 1 0 1 1 1 1 SPX domain Glyco_hydro_35 PF01301.14 AET39402.1 - 0.02 14.2 0.6 0.032 13.5 0.4 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 HisG PF01634.13 AET39403.1 - 1.5e-53 180.7 0.3 2.5e-53 179.9 0.2 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 AET39403.1 - 8.8e-25 86.4 0.0 1.7e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 AET39403.1 - 0.0062 16.1 0.1 0.012 15.2 0.0 1.4 1 1 0 1 1 1 1 NMT1/THI5 like WD40 PF00400.27 AET39404.1 - 1.1e-54 180.4 30.9 1.8e-10 40.2 0.9 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 AET39404.1 - 4.9e-15 54.9 0.4 1.4e-14 53.4 0.3 1.9 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 AET39404.1 - 2.9e-11 42.2 13.2 0.0066 14.6 0.1 5.4 2 2 4 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 AET39404.1 - 1.5e-09 37.2 0.4 4e-09 35.8 0.3 1.8 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 AET39404.1 - 0.00071 19.3 0.0 1.2 8.9 0.0 3.9 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 AET39404.1 - 0.0023 16.7 1.1 2.3 6.8 0.4 3.5 2 1 1 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 AET39404.1 - 0.086 12.2 0.7 21 4.4 0.1 3.0 3 0 0 3 3 3 0 PQQ-like domain CBM_21 PF03370.8 AET39405.1 - 1.3e-27 95.9 0.1 3.1e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 AET39405.1 - 0.035 14.1 1.8 2.3 8.3 0.4 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) ArfGap PF01412.13 AET39406.1 - 6.1e-37 125.9 0.1 9.7e-37 125.3 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Zn_Tnp_IS1595 PF12760.2 AET39406.1 - 0.071 12.9 1.6 0.22 11.3 1.1 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Cyt-b5 PF00173.23 AET39407.1 - 4.6e-20 71.2 0.0 7.5e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2269 PF10027.4 AET39407.1 - 0.061 13.1 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) AA_kinase PF00696.23 AET39408.1 - 3.2e-41 141.4 0.1 6.2e-41 140.5 0.0 1.5 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 AET39408.1 - 7.8e-14 50.8 0.3 1.7e-07 30.5 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 AET39408.1 - 5.9e-09 35.3 2.6 2.4e-06 26.9 0.3 2.6 2 0 0 2 2 2 2 ACT domain DUF1368 PF07112.6 AET39408.1 - 0.016 13.8 1.4 0.024 13.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) NAD_binding_1 PF00175.16 AET39409.1 - 1.5e-28 99.4 0.0 2.4e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AET39409.1 - 3.2e-26 91.3 0.0 4.9e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AET39409.1 - 9.5e-05 22.3 0.0 0.0037 17.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Cupin_8 PF13621.1 AET39410.1 - 4e-08 33.0 0.1 9.1e-08 31.8 0.1 1.6 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.24 AET39410.1 - 2.9e-07 30.0 5.2 2.9e-07 30.0 3.6 2.0 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 AET39410.1 - 0.0031 17.1 2.5 0.0083 15.8 1.7 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Cupin_4 PF08007.7 AET39410.1 - 0.013 14.7 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.17 AET39410.1 - 0.015 15.5 0.0 0.19 11.9 0.0 2.6 2 1 0 2 2 2 0 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 AET39410.1 - 0.12 12.3 2.4 0.31 11.0 1.6 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF1423 PF07227.6 AET39410.1 - 0.29 9.7 1.6 0.49 8.9 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) zf-HC5HC2H PF13771.1 AET39410.1 - 0.44 10.7 4.3 0.34 11.0 1.6 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_C48 PF02902.14 AET39411.1 - 3.9e-34 118.1 5.3 7.9e-34 117.1 3.6 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RINGv PF12906.2 AET39412.1 - 1.7e-14 53.5 6.7 3.2e-14 52.6 4.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 AET39412.1 - 1.2 9.0 9.1 0.48 10.3 4.4 1.9 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.3 AET39412.1 - 3.1 7.8 6.1 11 6.1 4.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain APC_CDC26 PF10471.4 AET39413.1 - 2.9e-16 59.9 13.1 5.6e-15 55.8 8.7 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex APC subunit 1 DUF2802 PF10975.3 AET39413.1 - 0.17 11.6 4.4 1.3 8.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) TSA PF03249.8 AET39413.1 - 0.32 9.4 4.0 0.32 9.4 2.7 1.2 1 0 0 1 1 1 0 Type specific antigen MMgT PF10270.4 AET39414.1 - 2.2e-25 89.1 0.1 2.6e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter STAG PF08514.6 AET39415.1 - 7.8e-09 35.2 8.7 1.1e-08 34.8 1.9 3.6 3 0 0 3 3 3 1 STAG domain HEAT PF02985.17 AET39415.1 - 0.014 15.3 0.5 0.5 10.5 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat CBM_48 PF02922.13 AET39416.1 - 0.0065 16.4 0.1 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF605 PF04652.11 AET39416.1 - 0.32 10.3 11.7 0.42 9.9 8.1 1.1 1 0 0 1 1 1 0 Vta1 like SR-25 PF10500.4 AET39416.1 - 0.44 9.9 15.9 0.66 9.3 11.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 AET39416.1 - 1.7 6.7 12.5 2.1 6.5 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Nop14 PF04147.7 AET39416.1 - 2.1 6.1 12.8 2.8 5.7 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 AET39417.1 - 2.3e-27 95.6 42.1 9.7e-23 80.4 14.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AET39417.1 - 1.2e-06 27.3 43.7 0.00061 18.4 9.4 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter Zip PF02535.17 AET39418.1 - 5.9e-48 163.4 5.1 1.6e-40 139.0 0.8 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter DUF2273 PF10031.4 AET39418.1 - 0.014 15.0 0.4 0.065 12.8 0.3 2.2 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF389 PF04087.9 AET39418.1 - 0.12 12.2 4.2 0.19 11.6 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF389) SWIRM PF04433.12 AET39419.1 - 4.9e-32 109.8 0.1 1.1e-31 108.8 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 AET39419.1 - 5.9e-10 38.5 3.6 9.2e-10 37.9 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 AET39419.1 - 1.1e-06 28.5 0.0 4.8e-05 23.3 0.0 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AET39419.1 - 1.3e-06 28.3 0.1 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Elf1 PF05129.8 AET39419.1 - 0.07 12.8 0.3 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-UBR PF02207.15 AET39419.1 - 0.14 11.8 1.2 0.27 10.9 0.8 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF4337 PF14235.1 AET39419.1 - 0.98 9.2 13.1 1.1 9.1 1.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4337) Erg28 PF03694.8 AET39420.1 - 2.6e-42 143.3 2.6 3.4e-42 142.9 1.8 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF308 PF03729.8 AET39420.1 - 0.0027 17.6 2.3 0.0042 17.0 0.4 2.1 2 0 0 2 2 2 1 Short repeat of unknown function (DUF308) p53-inducible11 PF14936.1 AET39420.1 - 0.012 15.5 1.2 0.015 15.2 0.9 1.0 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 EOS1 PF12326.3 AET39420.1 - 1.1 8.8 4.8 0.61 9.7 0.1 2.2 1 1 1 2 2 2 0 N-glycosylation protein F_actin_cap_B PF01115.12 AET39421.1 - 5.4e-91 304.0 0.1 6.3e-91 303.8 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pkinase PF00069.20 AET39422.1 - 3.3e-58 196.8 8.4 1.4e-56 191.5 5.8 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39422.1 - 8.8e-21 74.1 3.9 3.4e-16 59.0 0.1 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 AET39422.1 - 4.8e-06 26.4 0.1 3.5e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AET39422.1 - 0.0073 15.8 0.9 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pneumovirus_M2 PF06436.6 AET39422.1 - 0.04 13.1 0.6 0.099 11.8 0.4 1.6 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Kdo PF06293.9 AET39422.1 - 0.043 12.8 0.2 0.085 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF496 PF04363.7 AET39422.1 - 0.067 13.0 3.3 0.26 11.0 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF496) Sterile PF03015.14 AET39423.1 - 0.43 10.8 3.6 16 5.8 0.5 3.0 2 2 0 2 2 2 0 Male sterility protein bZIP_1 PF00170.16 AET39424.1 - 7.7e-16 57.8 11.0 1.7e-15 56.6 7.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AET39424.1 - 1.2e-07 31.3 9.3 1.2e-07 31.3 6.4 1.7 2 0 0 2 2 2 1 Basic region leucine zipper DUF2278 PF10042.4 AET39424.1 - 0.014 15.1 0.3 0.026 14.2 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) TFIIA PF03153.8 AET39424.1 - 0.021 14.7 14.3 0.025 14.4 9.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_Maf PF03131.12 AET39424.1 - 0.027 14.7 6.1 0.027 14.7 4.2 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor PAT1 PF09770.4 AET39424.1 - 0.97 7.5 30.1 1.2 7.2 20.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lipoprotein_11 PF03260.8 AET39425.1 - 0.0051 15.8 1.3 0.64 8.9 0.1 2.6 2 0 0 2 2 2 2 Lepidopteran low molecular weight (30 kD) lipoprotein YolD PF08863.5 AET39426.1 - 0.033 14.0 1.5 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 YolD-like protein DUF3068 PF11271.3 AET39426.1 - 0.1 11.6 3.7 0.5 9.3 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3068) Metallophos PF00149.23 AET39427.1 - 2.3e-29 102.2 6.0 3.3e-29 101.7 4.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DnaJ-X PF14308.1 AET39428.1 - 5e-55 185.9 3.5 5e-55 185.9 2.4 1.6 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 AET39428.1 - 2.7e-26 91.0 2.1 2.7e-26 91.0 1.5 2.8 3 0 0 3 3 3 1 DnaJ domain TEX19 PF15553.1 AET39428.1 - 0.13 12.0 0.6 1.7 8.4 0.2 2.4 2 0 0 2 2 2 0 Testis-expressed protein 19 Apq12 PF12716.2 AET39429.1 - 0.0014 18.2 13.4 0.0026 17.4 9.3 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Complex1_LYR PF05347.10 AET39430.1 - 1.2e-14 53.8 0.4 1.6e-14 53.4 0.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AET39430.1 - 4.5e-14 52.4 0.6 5.5e-14 52.1 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like CTD_bind PF04818.8 AET39430.1 - 0.016 15.4 0.2 0.023 14.9 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase II-binding domain. dDENN PF03455.14 AET39430.1 - 0.14 12.2 3.0 0.27 11.3 2.1 1.4 1 0 0 1 1 1 0 dDENN domain Ofd1_CTDD PF10637.4 AET39431.1 - 9e-89 297.1 1.4 1.7e-85 286.3 0.8 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 AET39431.1 - 8.1e-16 58.3 0.1 1.7e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BAR_2 PF10455.4 AET39432.1 - 1e-71 241.2 16.0 1e-71 241.2 11.1 2.1 2 1 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 AET39432.1 - 5.1e-12 45.7 11.9 5.1e-12 45.7 8.2 2.8 1 1 1 2 2 2 1 BAR domain DUF3692 PF12469.3 AET39432.1 - 0.068 13.4 0.9 0.29 11.3 0.6 2.2 1 1 0 1 1 1 0 CRISPR-associated protein BCDHK_Adom3 PF10436.4 AET39433.1 - 5.6e-25 87.7 0.9 7.3e-25 87.3 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AET39433.1 - 2.2e-20 72.4 0.0 3.9e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AET39433.1 - 3.2e-05 23.5 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AET39433.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Ribosomal_S18 PF01084.15 AET39434.1 - 4.1e-18 64.9 0.3 9.9e-18 63.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 Tim44 PF04280.10 AET39435.1 - 1.2e-32 112.9 0.0 2.4e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 Tim44-like domain Spore_III_AB PF09548.5 AET39435.1 - 0.011 15.5 0.2 0.037 13.7 0.1 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RNA_pol_A_bac PF01000.21 AET39437.1 - 6e-33 113.3 0.4 3.7e-32 110.8 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AET39437.1 - 3.2e-15 54.9 0.0 5e-15 54.3 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_biosynth PF00977.16 AET39438.1 - 3e-21 75.7 0.0 3.6e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Secretin_N_2 PF07655.8 AET39439.1 - 9.8 6.6 10.5 19 5.7 0.8 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain HLH PF00010.21 AET39440.1 - 5.5e-15 54.8 0.9 1e-14 53.9 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.4 AET39440.1 - 0.18 11.7 1.4 0.42 10.6 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) UCR_hinge PF02320.11 AET39441.1 - 3.6e-25 87.6 3.5 6.2e-25 86.9 2.4 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 AET39441.1 - 0.00014 21.5 17.0 0.0002 21.0 11.8 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region CobT PF06213.7 AET39441.1 - 0.0014 17.8 16.6 0.0016 17.6 11.5 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 AET39441.1 - 0.0034 15.4 21.3 0.0037 15.2 14.8 1.0 1 0 0 1 1 1 1 Nop14-like family DUF506 PF04720.7 AET39441.1 - 0.011 15.3 5.8 0.016 14.8 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) CDC45 PF02724.9 AET39441.1 - 0.013 13.6 13.5 0.013 13.5 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 AET39441.1 - 0.033 13.9 20.5 0.042 13.5 14.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-T PF15511.1 AET39441.1 - 0.047 12.9 13.5 0.054 12.7 9.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 AET39441.1 - 0.055 12.8 14.5 0.087 12.1 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 AET39441.1 - 0.064 11.9 14.7 0.087 11.5 10.2 1.1 1 0 0 1 1 1 0 Paf1 BUD22 PF09073.5 AET39441.1 - 0.075 12.0 15.0 0.081 11.9 10.4 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.6 AET39441.1 - 0.086 10.9 15.8 0.097 10.7 11.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ycf1 PF05758.7 AET39441.1 - 0.11 10.1 0.9 0.11 10.1 0.6 1.0 1 0 0 1 1 1 0 Ycf1 SGT1 PF07093.6 AET39441.1 - 0.12 10.7 12.7 0.13 10.6 8.8 1.1 1 0 0 1 1 1 0 SGT1 protein Vfa1 PF08432.5 AET39441.1 - 0.12 12.3 10.0 0.16 11.9 6.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tom22 PF04281.8 AET39441.1 - 0.15 11.5 21.4 0.26 10.8 14.9 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DNA_pol_phi PF04931.8 AET39441.1 - 0.22 9.2 31.9 0.28 8.8 22.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3449 PF11931.3 AET39441.1 - 0.26 10.7 7.5 0.39 10.2 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) VID27 PF08553.5 AET39441.1 - 0.3 9.2 11.9 0.39 8.8 8.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Tim54 PF11711.3 AET39441.1 - 0.3 9.6 4.8 0.36 9.3 3.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop53 PF07767.6 AET39441.1 - 0.34 9.8 11.8 0.41 9.5 8.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sporozoite_P67 PF05642.6 AET39441.1 - 0.55 8.0 10.0 0.62 7.8 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Utp14 PF04615.8 AET39441.1 - 0.66 8.0 14.2 0.82 7.7 9.9 1.1 1 0 0 1 1 1 0 Utp14 protein BTV_NS2 PF04514.7 AET39441.1 - 1.1 8.0 10.6 1.4 7.7 7.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Rhabdo_ncap PF00945.13 AET39441.1 - 1.2 7.6 5.6 1.4 7.4 3.9 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Herpes_TAF50 PF03326.8 AET39441.1 - 1.3 7.9 5.3 1.7 7.5 3.7 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) GCIP PF13324.1 AET39441.1 - 1.3 8.1 12.7 1.6 7.8 8.8 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Dicty_REP PF05086.7 AET39441.1 - 1.3 6.6 16.9 1.8 6.1 11.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Daxx PF03344.10 AET39441.1 - 1.7 7.0 25.3 2 6.7 17.5 1.1 1 0 0 1 1 1 0 Daxx Family eIF-3c_N PF05470.7 AET39441.1 - 2.7 5.9 13.1 3.2 5.7 9.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Astro_capsid PF03115.9 AET39441.1 - 3.4 5.8 8.9 3.7 5.6 6.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TFIIF_alpha PF05793.7 AET39441.1 - 3.6 5.8 18.7 4.1 5.6 13.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.10 AET39441.1 - 4.1 5.9 9.7 4.9 5.6 6.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_3_Rpc31 PF11705.3 AET39441.1 - 4.8 7.0 28.3 7.4 6.4 19.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2722 PF10846.3 AET39441.1 - 6 5.7 9.7 6.8 5.6 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.7 AET39441.1 - 7.1 5.7 21.0 12 5.0 14.6 1.4 1 0 0 1 1 1 0 NOA36 protein IFT57 PF10498.4 AET39441.1 - 9.9 4.7 15.3 12 4.4 10.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Ribosomal_L29e PF01779.12 AET39442.1 - 2e-23 81.9 10.7 2.8e-23 81.4 7.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Ribosomal_L2_C PF03947.13 AET39443.1 - 1.6e-40 137.9 2.3 2.6e-40 137.2 1.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AET39443.1 - 5.3e-13 48.7 0.1 1.2e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SMC_N PF02463.14 AET39444.1 - 1.6e-70 236.7 3.9 9.3e-70 234.2 2.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AET39444.1 - 1.7e-19 69.9 0.2 5.2e-19 68.3 0.1 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 AET39444.1 - 2.5e-14 54.0 16.7 2.5e-14 54.0 11.6 6.9 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 AET39444.1 - 7.3e-11 42.5 5.2 3.8e-06 27.0 0.9 4.3 2 2 0 4 4 4 2 AAA domain Fez1 PF06818.10 AET39444.1 - 6.6e-06 26.2 11.8 6.6e-06 26.2 8.2 5.4 3 2 2 5 5 5 2 Fez1 AAA_29 PF13555.1 AET39444.1 - 0.00032 20.1 0.0 0.00076 18.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 AET39444.1 - 0.0052 16.0 26.9 0.0052 16.0 18.6 7.7 3 2 4 7 7 7 2 Growth-arrest specific micro-tubule binding MscS_porin PF12795.2 AET39444.1 - 0.96 8.7 91.1 0.049 12.9 7.9 7.1 4 2 2 6 6 6 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 AET39444.1 - 1.7 7.7 37.0 0.7 9.0 3.0 5.8 2 2 3 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 AET39444.1 - 2.2 6.6 104.1 0.022 13.2 13.1 5.9 3 2 4 7 7 7 0 AAA domain FAD_binding_1 PF00667.15 AET39445.1 - 1.1e-63 214.6 0.0 1.8e-63 213.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 AET39445.1 - 1e-09 38.9 0.0 2.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 AET39445.1 - 0.0091 15.9 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase HEAT PF02985.17 AET39446.1 - 0.012 15.6 0.0 0.59 10.3 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat BAG PF02179.11 AET39447.1 - 6.2e-15 55.0 2.5 1.6e-14 53.7 1.8 1.7 1 0 0 1 1 1 1 BAG domain CDC37_N PF03234.9 AET39447.1 - 0.16 12.3 3.3 0.21 11.9 2.3 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Cnd2 PF05786.9 AET39447.1 - 5.9 5.2 8.8 0.38 9.2 1.8 1.8 2 0 0 2 2 2 0 Condensin complex subunit 2 Asp PF00026.18 AET39448.1 - 4.1e-65 220.1 0.1 6.3e-65 219.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AET39448.1 - 1.4e-08 34.8 0.2 1.1e-07 31.9 0.1 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AET39448.1 - 6.3e-05 23.3 4.7 0.037 14.5 0.0 3.9 4 0 0 4 4 4 2 Aspartyl protease Lum_binding PF00677.12 AET39449.1 - 9.6e-45 150.4 3.8 7.6e-23 80.2 0.3 2.2 2 0 0 2 2 2 2 Lumazine binding domain WD40 PF00400.27 AET39450.1 - 3e-09 36.4 9.6 0.07 13.0 0.0 7.2 8 0 0 8 8 8 3 WD domain, G-beta repeat PQQ PF01011.16 AET39450.1 - 0.00062 19.1 0.0 0.58 9.7 0.0 3.0 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 AET39450.1 - 0.007 15.8 0.3 0.28 10.6 0.2 3.1 1 1 0 1 1 1 1 PQQ-like domain IKI3 PF04762.7 AET39450.1 - 0.13 10.0 0.4 10 3.7 0.2 2.6 2 1 1 3 3 3 0 IKI3 family PQQ_3 PF13570.1 AET39450.1 - 0.51 10.6 3.6 17 5.8 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain Cut8_C PF08559.5 AET39451.1 - 1.6e-45 154.4 0.7 2.2e-45 154.0 0.5 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 AET39451.1 - 3e-10 39.7 2.7 5.9e-10 38.7 1.9 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain Sedlin_N PF04628.8 AET39454.1 - 1.4e-48 164.0 0.5 1.9e-48 163.6 0.4 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 AET39454.1 - 1e-05 25.2 0.3 2.3e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 Sybindin-like family MIS13 PF08202.6 AET39455.1 - 1e-66 225.0 6.0 1e-66 225.0 4.2 1.7 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Med22 PF06179.7 AET39456.1 - 2.7e-21 75.6 0.2 3.1e-21 75.4 0.1 1.0 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex dUTPase PF00692.14 AET39457.1 - 3.4e-44 149.4 0.0 3.9e-44 149.2 0.0 1.0 1 0 0 1 1 1 1 dUTPase Peptidase_M16 PF00675.15 AET39458.1 - 1.6e-30 105.7 0.2 4.4e-30 104.3 0.2 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AET39458.1 - 5.9e-10 39.1 0.1 7.2e-07 29.0 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Rrp15p PF07890.7 AET39459.1 - 1.9e-32 112.0 12.4 1.9e-32 112.0 8.6 1.7 2 0 0 2 2 2 1 Rrp15p Nop14 PF04147.7 AET39459.1 - 0.0053 14.7 16.9 0.0064 14.4 11.7 1.2 1 0 0 1 1 1 1 Nop14-like family Kinesin PF00225.18 AET39460.1 - 7.5e-100 333.8 3.0 1.7e-99 332.7 2.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Acyltransferase PF01553.16 AET39461.1 - 2.6e-15 56.0 0.0 5.4e-15 54.9 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 AET39462.1 - 0.02 14.2 0.0 0.057 12.8 0.0 1.8 1 1 0 1 1 1 0 Acyltransferase Ammonium_transp PF00909.16 AET39463.1 - 2.6e-116 388.4 25.5 3e-116 388.1 17.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COX6A PF02046.10 AET39463.1 - 0.067 13.1 0.1 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIa Metallophos PF00149.23 AET39464.1 - 1e-35 122.9 0.1 1.4e-35 122.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 AET39464.1 - 3.9e-21 74.4 0.6 7.9e-16 57.4 0.5 2.7 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 AET39464.1 - 1e-12 47.0 0.9 0.00042 19.8 0.3 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AET39464.1 - 8.8e-12 43.9 0.7 0.0074 16.1 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat PPP5 PF08321.7 AET39464.1 - 2.9e-06 27.2 0.1 0.0012 18.8 0.0 2.9 2 1 0 2 2 2 1 PPP5 TPR repeat region TPR_8 PF13181.1 AET39464.1 - 6.2e-05 22.4 1.2 1.8 8.5 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 AET39464.1 - 0.00011 22.0 0.7 0.0068 16.2 0.1 3.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 AET39464.1 - 0.00029 20.7 0.1 0.63 10.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AET39464.1 - 0.0068 17.0 0.2 0.38 11.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AET39464.1 - 0.007 16.2 0.5 5 7.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AET39464.1 - 0.15 12.8 0.8 46 5.0 0.0 3.8 1 1 3 4 4 4 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.11 AET39465.1 - 2.4e-26 92.5 19.0 2.4e-26 92.5 13.1 1.4 2 0 0 2 2 2 1 TLC domain Flavin_Reduct PF01613.13 AET39466.1 - 6.6e-26 91.0 0.4 3.5e-25 88.6 0.3 1.8 1 1 0 1 1 1 1 Flavin reductase like domain Telomere_reg-2 PF10193.4 AET39468.1 - 6.5e-23 81.1 1.8 6.5e-23 81.1 1.3 2.9 2 1 0 2 2 2 1 Telomere length regulation protein Rhomboid PF01694.17 AET39469.1 - 5.7e-29 101.0 17.1 5.7e-29 101.0 11.9 1.7 2 0 0 2 2 2 1 Rhomboid family DUF3982 PF13138.1 AET39470.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) Pescadillo_N PF06732.6 AET39471.1 - 1.2e-120 401.9 1.6 1.2e-120 401.9 1.1 2.4 3 1 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 AET39471.1 - 1.9e-11 43.9 0.0 5.6e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Med18 PF09637.5 AET39472.1 - 1.1e-64 218.4 0.1 1.2e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2087 PF09860.4 AET39472.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) VMA21 PF09446.5 AET39473.1 - 2.8e-14 52.7 8.7 3.4e-14 52.4 6.1 1.1 1 0 0 1 1 1 1 VMA21-like domain MscS_TM PF12794.2 AET39473.1 - 0.012 14.2 0.1 0.012 14.2 0.1 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DAD PF02109.11 AET39473.1 - 0.077 13.0 0.3 0.086 12.9 0.2 1.1 1 0 0 1 1 1 0 DAD family DUF1430 PF07242.6 AET39473.1 - 0.14 12.2 2.4 0.17 11.9 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) TraG_N PF07916.6 AET39473.1 - 0.21 10.0 3.3 0.23 9.8 2.3 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region ATP-synt_S1 PF05827.7 AET39474.1 - 6.7e-06 25.6 0.2 0.00046 19.6 0.0 2.1 2 0 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Polysacc_synt PF01943.12 AET39474.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EST1 PF10374.4 AET39474.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Telomerase activating protein Est1 IF-2B PF01008.12 AET39475.1 - 1.5e-80 270.2 0.0 1.8e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyclin_N PF00134.18 AET39476.1 - 4.5e-40 136.1 0.2 1.7e-39 134.3 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AET39476.1 - 2.7e-30 104.7 1.3 3e-29 101.3 0.0 3.1 3 0 0 3 3 3 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 AET39477.1 - 2.1e-38 130.7 1.8 2.1e-38 130.7 1.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AET39477.1 - 6.3e-17 61.5 0.6 2.8e-16 59.5 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF2476 PF10630.4 AET39477.1 - 0.0041 17.0 0.4 0.0065 16.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2476) Sporozoite_P67 PF05642.6 AET39477.1 - 0.34 8.7 6.4 0.54 8.0 4.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.27 AET39479.1 - 1.1e-26 91.6 1.2 7.9e-08 31.8 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AET39479.1 - 0.017 13.4 1.1 0.4 8.9 0.2 2.7 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF3639 PF12341.3 AET39480.1 - 1.7e-09 37.5 0.4 4.1e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) COG2 PF06148.6 AET39481.1 - 8.8e-11 41.8 6.1 1.7e-10 40.8 3.0 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.10 AET39481.1 - 0.021 14.0 2.0 0.026 13.7 1.2 1.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_L29 PF00831.18 AET39481.1 - 0.027 14.1 0.4 10 5.8 0.1 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein Mating_N PF12731.2 AET39481.1 - 0.04 13.7 4.0 0.079 12.8 1.3 2.3 2 0 0 2 2 2 0 Mating-type protein beta 1 Apolipoprotein PF01442.13 AET39481.1 - 0.11 12.0 0.3 0.31 10.5 0.1 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4297 PF14130.1 AET39481.1 - 0.11 12.3 2.6 0.19 11.6 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4297) DASH_Dad3 PF08656.5 AET39481.1 - 7.7 6.2 7.6 3.4 7.4 0.4 2.9 2 1 1 3 3 3 0 DASH complex subunit Dad3 Nup54 PF13874.1 AET39482.1 - 2.1e-41 140.9 3.7 2.1e-41 140.9 2.6 2.5 2 0 0 2 2 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 AET39482.1 - 5.6e-15 55.5 99.6 8.4e-13 48.5 33.2 4.4 1 1 2 3 3 3 2 Nucleoporin FG repeat region SprA-related PF12118.3 AET39482.1 - 0.0039 16.5 35.3 0.0091 15.3 24.5 1.5 1 0 0 1 1 1 1 SprA-related family Ndc1_Nup PF09531.5 AET39482.1 - 0.37 9.1 13.3 0.44 8.8 9.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDHD PF02862.12 AET39482.1 - 0.52 10.0 15.9 1.2 8.8 11.0 1.6 1 0 0 1 1 1 0 DDHD domain GOLD_2 PF13897.1 AET39482.1 - 0.73 10.0 6.6 1.7 8.8 4.6 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PAT1 PF09770.4 AET39482.1 - 0.89 7.7 51.6 1.4 7.1 35.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 AET39482.1 - 1.4 8.7 15.8 2.5 7.9 10.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF605 PF04652.11 AET39482.1 - 4 6.7 31.0 7.2 5.8 21.5 1.4 1 0 0 1 1 1 0 Vta1 like AIF_C PF14721.1 AET39482.1 - 4.1 7.6 11.5 11 6.2 8.0 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term OATP PF03137.15 AET39482.1 - 5.4 4.9 13.4 8.1 4.3 9.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.13 AET39482.1 - 6.7 5.1 11.9 10 4.5 8.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier Tom5 PF10642.4 AET39484.1 - 2.9e-22 78.0 0.6 3.1e-22 77.9 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.6 AET39485.1 - 1.3e-13 50.2 0.2 5.3e-13 48.2 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Phasin PF05597.6 AET39485.1 - 1.5 8.5 9.5 0.04 13.6 1.0 2.3 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Ribosom_S12_S23 PF00164.20 AET39486.1 - 1.8e-41 140.3 0.4 2.1e-41 140.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acetyltransf_1 PF00583.19 AET39488.1 - 2.9e-09 36.8 0.0 4.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AET39488.1 - 9.2e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 AET39488.1 - 0.0031 17.6 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AET39488.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AET39488.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LSM14 PF12701.2 AET39489.1 - 3.3e-26 90.9 0.0 6.3e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 AET39489.1 - 4.1e-11 43.3 16.4 4.1e-11 43.3 11.3 2.5 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.1 AET39489.1 - 6.2e-05 22.8 0.1 0.00015 21.5 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain DUF1509 PF07420.6 AET39489.1 - 0.0046 16.2 2.0 0.0056 16.0 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) Mito_carr PF00153.22 AET39490.1 - 1.9e-53 178.1 4.8 4.1e-18 64.8 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein RRM_1 PF00076.17 AET39491.1 - 1.6e-70 232.7 12.2 3.2e-17 61.9 0.0 6.3 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET39491.1 - 1.8e-64 213.6 2.7 1.6e-15 56.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET39491.1 - 4.7e-42 141.6 0.2 5.9e-09 35.6 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AET39491.1 - 0.0032 17.1 0.0 1.5 8.6 0.0 3.6 3 1 1 4 4 4 2 Limkain b1 CwfJ_C_1 PF04677.10 AET39492.1 - 3.7e-31 107.3 0.9 7.7e-31 106.2 0.6 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 AET39492.1 - 4.6e-22 78.3 3.5 8.8e-22 77.4 2.4 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 PFU PF09070.6 AET39492.1 - 0.039 13.9 0.2 1.1 9.2 0.0 2.9 2 1 1 3 3 3 0 PFU (PLAA family ubiquitin binding) Pkinase PF00069.20 AET39493.1 - 1.1e-52 178.7 0.0 8e-52 175.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39493.1 - 1.1e-27 96.6 0.1 1.2e-18 67.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 AET39493.1 - 4.1e-05 23.9 0.4 0.00012 22.4 0.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AET39493.1 - 0.0005 19.1 0.1 0.0097 14.8 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 AET39493.1 - 0.056 13.1 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Nop PF01798.13 AET39494.1 - 1.1e-39 135.1 1.2 1.6e-39 134.5 0.1 1.8 2 0 0 2 2 2 1 Putative snoRNA binding domain Prp31_C PF09785.4 AET39494.1 - 2e-27 96.0 3.6 4e-27 95.0 2.5 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 AET39494.1 - 2.4e-07 30.4 0.8 8.8e-07 28.6 0.1 2.3 2 0 0 2 2 2 1 NOSIC (NUC001) domain RNA_pol_A_bac PF01000.21 AET39495.1 - 1.1e-28 99.6 0.0 2.5e-28 98.4 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AET39495.1 - 2.2e-16 58.6 0.0 2.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2456 PF10445.4 AET39496.1 - 0.015 15.2 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) DUF1746 PF08508.5 AET39496.1 - 0.022 14.7 0.4 0.41 10.5 0.0 2.7 2 2 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Nrap PF03813.9 AET39497.1 - 0 1207.3 4.1 0 1207.1 2.8 1.0 1 0 0 1 1 1 1 Nrap protein EMP24_GP25L PF01105.19 AET39499.1 - 2.8e-34 118.4 0.3 3.2e-34 118.2 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TP6A_N PF04406.9 AET39500.1 - 2.6e-12 46.1 0.6 7.4e-12 44.7 0.4 1.8 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 AET39500.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) E3_UbLigase_EDD PF11547.3 AET39500.1 - 0.073 12.5 0.2 0.19 11.2 0.2 1.7 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD TauD PF02668.11 AET39501.1 - 6.5e-51 173.4 0.0 9.5e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pet127 PF08634.5 AET39502.1 - 1.6e-114 381.7 1.3 2.5e-114 381.0 0.9 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 PQ-loop PF04193.9 AET39503.1 - 1.5e-09 37.2 16.4 1.7e-08 33.8 1.2 3.9 3 1 1 4 4 4 2 PQ loop repeat ARD PF03079.9 AET39504.1 - 9.3e-45 152.3 1.2 1.1e-44 152.1 0.8 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 AET39504.1 - 4.4e-10 38.9 0.1 7.6e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AET39504.1 - 3.6e-08 33.1 0.0 5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 AET39504.1 - 0.0023 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 AET39504.1 - 0.051 13.0 0.0 0.091 12.2 0.0 1.6 1 1 0 1 1 1 0 Cupin-like domain Cupin_3 PF05899.7 AET39504.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1498 PF07385.7 AET39504.1 - 0.081 12.0 0.0 0.14 11.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1498) JmjC PF02373.17 AET39504.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 JmjC domain, hydroxylase SRP1_TIP1 PF00660.12 AET39505.1 - 1.1e-31 108.6 0.4 2e-31 107.9 0.3 1.3 1 0 0 1 1 1 1 Seripauperin and TIP1 family EF-hand_4 PF12763.2 AET39506.1 - 4.5e-25 87.3 0.0 9.4e-13 47.8 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 AET39506.1 - 6.9e-08 31.2 0.0 0.0013 17.9 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 AET39506.1 - 8.9e-07 28.9 0.0 0.0037 17.3 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AET39506.1 - 3.9e-05 23.1 0.1 0.29 11.1 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain DUF1720 PF08226.6 AET39506.1 - 0.0004 20.3 45.6 0.00053 19.9 12.8 9.6 5 2 4 9 9 9 4 Domain of unknown function (DUF1720) RRM_1 PF00076.17 AET39507.1 - 1.1e-15 57.0 0.0 1.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET39507.1 - 1.3e-11 44.3 0.0 3.6e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET39507.1 - 2.5e-09 36.8 0.0 1.1e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_6 PF03737.10 AET39508.1 - 6.4e-35 120.2 0.0 8e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase DnaJ-X PF14308.1 AET39509.1 - 6.4e-63 211.7 0.7 6.4e-63 211.7 0.5 2.7 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 AET39509.1 - 2.3e-23 81.6 1.6 2.3e-23 81.6 1.1 2.7 3 0 0 3 3 3 1 DnaJ domain DUF4532 PF15046.1 AET39509.1 - 0.027 13.4 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) Dsh_C PF12316.3 AET39509.1 - 1.6 8.7 7.1 2.6 8.1 4.9 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Hid1 PF12722.2 AET39509.1 - 3.4 5.2 10.8 5.4 4.5 7.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 AET39509.1 - 6.6 6.5 6.0 1.8 8.3 2.2 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3210 PF11489.3 AET39510.1 - 2.3e-21 76.1 13.1 2.3e-21 76.1 9.1 3.9 3 1 0 4 4 4 2 Protein of unknown function (DUF3210) DNA_ligase_A_C PF04679.10 AET39510.1 - 0.039 14.3 0.6 0.2 12.0 0.0 2.4 3 0 0 3 3 3 0 ATP dependent DNA ligase C terminal region NTF2 PF02136.15 AET39511.1 - 2.5e-35 121.4 0.5 2.8e-35 121.2 0.4 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 AET39511.1 - 0.001 18.1 0.1 0.0013 17.8 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4440 PF14534.1 AET39511.1 - 0.097 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Sec3_C PF09763.4 AET39512.1 - 4.2e-166 554.0 25.6 6.7e-166 553.3 17.7 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 AET39512.1 - 5.6e-26 90.2 1.5 5.6e-26 90.2 1.0 2.8 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 AET39512.1 - 1.1e-11 43.9 5.3 1.1e-11 43.9 3.7 2.0 3 0 0 3 3 3 1 Vps52 / Sac2 family DEAD PF00270.24 AET39513.1 - 3.3e-21 75.5 0.2 7.2e-20 71.1 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET39513.1 - 5.2e-21 74.3 0.0 2.1e-20 72.3 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET39513.1 - 4.3e-17 62.5 0.0 4.3e-17 62.5 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AET39513.1 - 5.1e-06 25.5 0.0 1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.11 AET39513.1 - 0.0088 15.2 0.1 0.037 13.2 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 AET39513.1 - 0.07 13.2 0.0 0.26 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain PUA PF01472.15 AET39514.1 - 4.1e-21 74.4 0.0 6.6e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.5 AET39514.1 - 0.034 13.9 0.1 0.075 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) DUF1133 PF06576.6 AET39514.1 - 0.12 11.5 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) LRR_4 PF12799.2 AET39515.1 - 2.3e-17 62.1 23.8 1.6e-05 24.4 1.7 6.4 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 AET39515.1 - 2.4e-12 46.3 0.0 4.2e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_6 PF13516.1 AET39515.1 - 1e-11 43.6 16.1 0.58 10.4 0.1 8.9 9 0 0 9 9 9 5 Leucine Rich repeat LRR_8 PF13855.1 AET39515.1 - 2.8e-11 43.0 20.6 0.00016 21.3 2.1 5.8 2 2 4 6 6 6 4 Leucine rich repeat LRR_7 PF13504.1 AET39515.1 - 1.4e-06 27.4 12.8 1.9 9.0 0.0 8.2 8 0 0 8 8 8 2 Leucine rich repeat LRR_1 PF00560.28 AET39515.1 - 1.6e-06 27.3 22.5 0.086 12.9 0.0 8.7 9 1 0 9 9 9 3 Leucine Rich Repeat DUF3340 PF11818.3 AET39515.1 - 0.032 14.1 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) LRR_9 PF14580.1 AET39515.1 - 0.12 11.9 3.0 0.65 9.5 0.3 2.8 3 1 0 3 3 3 0 Leucine-rich repeat GN3L_Grn1 PF08701.6 AET39516.1 - 1.2e-24 86.0 13.7 4.2e-24 84.2 9.5 2.0 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 AET39516.1 - 1e-20 73.8 0.1 4e-15 55.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AET39516.1 - 4.4e-09 35.7 0.1 2.4e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AET39516.1 - 8.4e-06 25.3 1.0 0.014 14.8 0.0 3.0 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AET39516.1 - 2.9e-05 23.9 2.8 0.2 11.4 0.3 3.4 2 2 0 2 2 2 2 Dynamin family DUF258 PF03193.11 AET39516.1 - 0.00043 19.4 0.2 0.00079 18.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 AET39516.1 - 0.0034 16.5 0.1 0.022 13.8 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 AET39516.1 - 0.0068 16.8 0.8 0.41 11.1 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 AET39516.1 - 0.032 13.0 0.1 0.077 11.7 0.0 1.6 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 AET39516.1 - 0.06 12.7 0.1 2.6 7.4 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 AET39516.1 - 0.45 11.3 5.3 0.86 10.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain TFIIB PF00382.14 AET39517.1 - 2e-50 168.4 2.3 3e-26 91.0 0.4 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AET39517.1 - 1.4e-13 49.9 0.8 2.4e-13 49.1 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Poxvirus PF06227.7 AET39517.1 - 0.067 12.7 0.2 0.096 12.2 0.1 1.4 1 0 0 1 1 1 0 dsDNA Poxvirus Cyclin_C PF02984.14 AET39517.1 - 0.095 12.6 0.2 0.35 10.8 0.0 2.0 2 1 0 3 3 3 0 Cyclin, C-terminal domain GDA1_CD39 PF01150.12 AET39518.1 - 8.2e-129 429.8 0.4 1.1e-128 429.4 0.3 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family NAD_binding_10 PF13460.1 AET39519.1 - 7.2e-11 42.4 0.0 9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 AET39519.1 - 3.7e-10 38.8 0.0 6.8e-09 34.6 0.0 2.0 1 1 1 2 2 2 1 HIM1 Epimerase PF01370.16 AET39519.1 - 1e-06 28.3 0.0 1.8e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 AET39519.1 - 0.00019 20.7 0.0 0.00051 19.3 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 AET39519.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Hexapep PF00132.19 AET39520.1 - 1.2e-06 27.7 10.5 0.00062 19.1 1.5 4.7 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AET39520.1 - 0.0028 17.1 13.0 0.036 13.6 2.8 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase SseB PF07179.7 AET39520.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 SseB protein N-terminal domain PMI_typeI PF01238.16 AET39521.1 - 1.3e-146 488.3 0.0 1.5e-146 488.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 AET39521.1 - 0.012 15.3 0.0 6.8 6.3 0.0 2.7 3 0 0 3 3 3 0 AraC-like ligand binding domain Nop16 PF09420.5 AET39522.1 - 1.1e-56 191.3 11.1 1.3e-56 191.1 7.7 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 PYC_OADA PF02436.13 AET39522.1 - 0.19 11.1 2.3 1.5 8.2 0.0 2.2 1 1 1 2 2 2 0 Conserved carboxylase domain RRM_1 PF00076.17 AET39523.1 - 8.2e-18 63.8 0.1 1.6e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET39523.1 - 1.5e-12 47.3 0.0 3.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET39523.1 - 1.3e-08 34.5 0.1 3.4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AET39523.1 - 0.026 14.2 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BTB PF00651.26 AET39524.1 - 3.4e-22 78.5 0.7 3.4e-12 46.3 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 AET39524.1 - 4.4e-11 42.9 0.0 1.2e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AET39524.1 - 1.5e-10 40.3 0.5 1.2e-06 28.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 AET39524.1 - 8.6e-09 35.6 0.3 3e-08 33.9 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET39524.1 - 1.3e-07 31.1 0.4 0.0018 18.3 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 AET39524.1 - 2.7e-05 24.2 0.8 0.0019 18.4 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Syja_N PF02383.13 AET39525.1 - 2.4e-63 213.8 0.1 4.3e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 AET39525.1 - 5.9e-24 85.3 0.0 8.5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2130 PF09903.4 AET39526.1 - 0.011 14.4 0.1 0.012 14.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) UPF0184 PF03670.8 AET39526.1 - 0.012 15.7 0.9 0.014 15.5 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) BLOC1_2 PF10046.4 AET39526.1 - 0.021 14.9 0.5 0.026 14.6 0.3 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps5 PF09325.5 AET39526.1 - 0.026 13.7 0.4 0.031 13.5 0.3 1.0 1 0 0 1 1 1 0 Vps5 C terminal like PilJ PF13675.1 AET39526.1 - 0.026 14.8 0.3 0.031 14.5 0.2 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term XkdN PF08890.6 AET39526.1 - 0.029 14.0 0.2 0.035 13.8 0.2 1.1 1 0 0 1 1 1 0 Phage XkdN-like protein CENP-Q PF13094.1 AET39526.1 - 0.038 14.0 1.1 0.039 13.9 0.8 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF948 PF06103.6 AET39526.1 - 0.063 13.1 0.1 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) T2SF PF00482.18 AET39526.1 - 0.068 13.0 0.4 0.075 12.9 0.3 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Paralemmin PF03285.10 AET39526.1 - 0.1 12.0 0.7 0.11 11.9 0.5 1.1 1 0 0 1 1 1 0 Paralemmin V_ATPase_I PF01496.14 AET39526.1 - 0.2 9.4 0.6 0.18 9.5 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 AET39526.1 - 0.37 10.3 2.0 0.41 10.2 1.4 1.1 1 0 0 1 1 1 0 IncA protein DDOST_48kD PF03345.9 AET39527.1 - 2.2e-131 438.3 2.7 2.4e-131 438.1 1.9 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Prefoldin_2 PF01920.15 AET39528.1 - 3.3e-22 78.2 7.6 3.6e-22 78.1 5.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.6 AET39528.1 - 0.033 14.0 7.7 0.035 13.9 0.7 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) AAA_32 PF13654.1 AET39528.1 - 0.083 11.5 2.1 0.1 11.2 1.4 1.0 1 0 0 1 1 1 0 AAA domain Takusan PF04822.8 AET39528.1 - 0.086 12.6 1.7 0.17 11.7 1.2 1.5 1 1 0 1 1 1 0 Takusan Prefoldin PF02996.12 AET39528.1 - 0.099 12.2 6.4 0.98 9.0 0.7 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF342 PF03961.8 AET39528.1 - 0.1 11.0 7.2 0.14 10.5 5.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 AET39528.1 - 0.12 11.4 3.8 0.15 11.1 2.3 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 AET39528.1 - 0.13 12.0 5.9 3 7.7 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 AET39528.1 - 0.14 12.4 4.8 1 9.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Spc24 PF08286.6 AET39528.1 - 0.38 10.4 7.5 0.2 11.3 1.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DASH_Dad3 PF08656.5 AET39528.1 - 0.52 10.0 4.2 1.1 8.9 0.9 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 IncA PF04156.9 AET39528.1 - 1.2 8.6 4.5 2.3 7.7 3.1 1.6 1 1 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 AET39528.1 - 2.4 8.1 4.8 6.3 6.8 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor DUF724 PF05266.9 AET39528.1 - 3.1 7.3 6.4 70 2.9 4.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF972 PF06156.8 AET39528.1 - 3.2 8.1 5.9 7.5 6.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Lipoprotein_6 PF01441.14 AET39529.1 - 0.0049 16.7 3.1 0.0076 16.1 2.2 1.2 1 0 0 1 1 1 1 Lipoprotein NPV_P10 PF05531.7 AET39529.1 - 0.05 13.8 9.2 0.81 9.9 1.6 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LOH1CR12 PF10158.4 AET39529.1 - 0.13 12.0 4.8 0.35 10.6 3.3 1.7 1 1 1 2 2 2 0 Tumour suppressor protein Baculo_PEP_C PF04513.7 AET39529.1 - 0.17 11.6 4.3 0.67 9.7 2.9 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 AET39529.1 - 0.18 9.3 3.6 0.24 8.8 2.5 1.2 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.7 AET39529.1 - 0.2 11.4 7.1 0.79 9.5 0.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Flagellin_C PF00700.16 AET39529.1 - 0.24 11.5 3.6 5.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region FlaC_arch PF05377.6 AET39529.1 - 0.47 10.3 4.0 3.5 7.6 0.5 3.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.8 AET39529.1 - 0.54 9.6 3.5 0.73 9.1 1.9 1.6 1 1 1 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.5 AET39529.1 - 1 9.5 10.4 0.16 12.0 1.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 AET39529.1 - 1.3 8.9 5.2 1.1 9.1 0.8 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 AET39529.1 - 1.6 7.6 4.3 2.3 7.2 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein ParA PF10609.4 AET39530.1 - 4.7e-36 122.5 0.1 7.5e-36 121.8 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 AET39530.1 - 6.3e-17 61.6 0.0 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 AET39530.1 - 1.8e-06 27.2 0.0 9.8e-06 24.8 0.0 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 AET39530.1 - 1.6e-05 24.1 1.4 0.00012 21.2 0.3 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 AET39530.1 - 4.2e-05 23.5 0.0 0.00083 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AET39530.1 - 0.0016 17.2 0.3 0.0025 16.6 0.2 1.2 1 0 0 1 1 1 1 ArgK protein YhjQ PF06564.7 AET39530.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.4 1 1 0 1 1 1 1 YhjQ protein Fer4_NifH PF00142.13 AET39530.1 - 0.023 13.8 0.1 0.17 11.0 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 AET39530.1 - 0.089 12.3 0.7 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AET39530.1 - 0.092 12.1 0.2 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 AET39530.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SNARE PF05739.14 AET39531.1 - 6.6e-08 32.1 0.5 1.2e-07 31.3 0.3 1.4 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.16 AET39531.1 - 0.014 14.9 2.0 0.028 13.9 1.4 1.6 1 1 0 1 1 1 0 Synaptobrevin AIP3 PF03915.8 AET39531.1 - 0.05 12.5 0.8 0.054 12.3 0.6 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Thioredoxin PF00085.15 AET39532.1 - 1.5e-16 59.9 0.4 1.8e-14 53.2 0.0 3.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 AET39532.1 - 1.1e-07 31.8 4.4 0.00043 20.1 0.4 4.6 3 1 1 4 4 4 2 Thioredoxin-like domain Mito_carr PF00153.22 AET39533.1 - 3.6e-67 222.1 4.0 5e-24 83.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Gti1_Pac2 PF09729.4 AET39535.1 - 2.3e-57 193.5 5.5 6.8e-55 185.4 0.0 2.5 2 0 0 2 2 2 1 Gti1/Pac2 family Na_trans_assoc PF06512.8 AET39535.1 - 0.18 11.7 3.8 0.27 11.1 2.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Zip PF02535.17 AET39535.1 - 0.27 10.1 5.4 0.44 9.4 3.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.1 AET39535.1 - 2.7 7.6 9.1 4.9 6.8 6.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A bZIP_1 PF00170.16 AET39536.1 - 3e-14 52.7 10.4 6.1e-14 51.7 7.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AET39536.1 - 9.2e-12 44.6 9.6 1.6e-11 43.8 6.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 AET39536.1 - 0.0081 16.4 4.3 0.016 15.4 3.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor GRASP55_65 PF04495.9 AET39537.1 - 6.3e-05 22.9 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 AET39537.1 - 9e-05 22.5 0.1 0.00014 22.0 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 AET39537.1 - 0.00021 21.0 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain IFP_35_N PF07334.8 AET39537.1 - 0.035 14.0 0.3 0.068 13.1 0.2 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Urm1 PF09138.6 AET39538.1 - 3.4e-35 120.0 0.5 3.8e-35 119.8 0.4 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 AET39538.1 - 0.0078 16.6 0.0 0.0096 16.3 0.0 1.2 1 0 0 1 1 1 1 ThiS family YchF-GTPase_C PF06071.8 AET39538.1 - 0.086 12.6 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF933) SWIB PF02201.13 AET39538.1 - 0.12 12.0 0.1 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 SWIB/MDM2 domain ATP-synt PF00231.14 AET39539.1 - 6.1e-70 235.8 7.1 6.9e-70 235.6 4.9 1.0 1 0 0 1 1 1 1 ATP synthase Folliculin PF11704.3 AET39539.1 - 0.035 13.7 2.7 0.14 11.7 0.7 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Fig1 PF12351.3 AET39540.1 - 4.9e-50 169.9 1.4 4.9e-50 169.9 1.0 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 AET39540.1 - 0.0041 16.7 14.0 0.0085 15.6 9.7 1.5 1 1 0 1 1 1 1 SUR7/PalI family SH3_6 PF12913.2 AET39540.1 - 0.028 13.6 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type DUF2231 PF09990.4 AET39540.1 - 7 7.0 7.6 1 9.7 0.6 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) AMP-binding PF00501.23 AET39541.1 - 1.5e-59 201.4 0.0 1.8e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AET39541.1 - 0.00073 20.4 0.0 0.0013 19.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyltransferase PF01553.16 AET39542.1 - 2.4e-27 94.9 0.0 4e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4328 PF14219.1 AET39542.1 - 0.23 10.7 3.4 0.063 12.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) O-antigen_lig PF13425.1 AET39542.1 - 6.8 6.6 11.6 1.3 9.0 4.3 2.3 2 1 0 2 2 2 0 O-antigen ligase like membrane protein MFS_1 PF07690.11 AET39543.1 - 2.3e-39 135.1 28.8 2.5e-39 134.9 16.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.8 AET39544.1 - 0.026 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LKAAEAR PF15478.1 AET39544.1 - 0.091 13.0 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif DUF3446 PF11928.3 AET39545.1 - 0.023 14.8 0.2 0.027 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) YCII PF03795.9 AET39546.1 - 6.2e-07 29.5 0.0 8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Profilin PF00235.14 AET39547.1 - 8.2e-39 132.4 0.2 9.2e-39 132.3 0.1 1.0 1 0 0 1 1 1 1 Profilin Leo1 PF04004.8 AET39548.1 - 5.6e-45 153.1 2.3 8.4e-45 152.5 0.0 2.3 3 0 0 3 3 3 1 Leo1-like protein HUN PF08729.5 AET39548.1 - 0.0072 16.1 11.1 0.027 14.3 7.7 2.1 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Glyco_hydro_18 PF00704.23 AET39549.1 - 2.1e-73 247.7 3.5 2.5e-73 247.4 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GPP34 PF05719.6 AET39550.1 - 7.3e-62 209.0 0.0 9.4e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) UCH PF00443.24 AET39551.1 - 3.5e-59 200.1 1.7 3.5e-59 200.1 1.2 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 AET39551.1 - 1.1e-41 140.0 5.2 5.8e-17 60.8 0.3 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 AET39551.1 - 5.2e-10 39.2 5.6 1.9e-08 34.1 3.9 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DnaJ PF00226.26 AET39551.1 - 0.0025 17.5 0.5 0.24 11.1 0.0 3.1 3 0 0 3 3 3 1 DnaJ domain EF-hand_1 PF00036.27 AET39552.1 - 2e-28 95.4 6.1 1.2e-07 30.4 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 AET39552.1 - 4.5e-25 85.2 3.0 2.7e-06 26.7 0.1 4.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 AET39552.1 - 5.2e-24 84.1 4.1 8.3e-15 54.6 0.2 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AET39552.1 - 4.1e-19 67.9 6.0 2.6e-10 39.7 0.0 3.8 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 AET39552.1 - 7.2e-19 66.2 9.0 1.1e-05 24.5 0.2 5.3 5 1 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 AET39552.1 - 3.7e-06 26.9 0.8 0.19 11.7 0.0 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 AET39552.1 - 3.3e-05 23.5 5.4 0.43 10.3 0.1 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AET39552.1 - 0.00059 19.6 0.1 0.023 14.6 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain S10_plectin PF03501.10 AET39552.1 - 0.012 15.4 0.1 0.025 14.4 0.0 1.6 1 1 0 1 1 1 0 Plectin/S10 domain EF-hand_10 PF14788.1 AET39552.1 - 0.014 15.0 0.8 3.2 7.4 0.0 3.4 3 0 0 3 3 3 0 EF hand Tenui_NCP PF04876.7 AET39552.1 - 0.11 12.0 0.1 0.93 9.0 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein COQ7 PF03232.8 AET39553.1 - 7.9e-74 246.8 0.0 1e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 YTH PF04146.10 AET39554.1 - 3.4e-38 130.3 0.5 5.1e-38 129.8 0.3 1.2 1 0 0 1 1 1 1 YT521-B-like domain Syntaxin-6_N PF09177.6 AET39554.1 - 0.05 14.0 0.6 0.1 12.9 0.1 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Sel1 PF08238.7 AET39555.1 - 1.2e-13 51.2 18.6 1.5e-05 25.4 0.3 7.5 9 0 0 9 9 8 4 Sel1 repeat TPR_2 PF07719.12 AET39555.1 - 0.00051 19.7 9.1 0.19 11.7 0.3 5.7 6 1 0 6 6 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 AET39555.1 - 0.0033 17.0 6.9 1.7 8.6 0.1 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 AET39555.1 - 0.0046 16.4 6.3 1.8 8.2 0.3 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 AET39555.1 - 0.012 16.2 6.4 0.064 13.9 0.3 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 AET39555.1 - 0.026 14.3 4.3 0.09 12.6 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AET39555.1 - 0.027 14.9 7.8 24 5.6 0.0 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 AET39555.1 - 0.035 13.7 7.1 0.24 11.0 1.3 4.2 2 1 1 3 3 3 0 TPR repeat Apc3 PF12895.2 AET39555.1 - 0.069 13.2 0.1 0.069 13.2 0.1 2.6 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AET39555.1 - 0.081 13.2 3.1 0.11 12.8 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AET39555.1 - 0.22 11.4 6.4 2.1 8.3 0.6 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Dynactin_p62 PF05502.8 AET39556.1 - 1.1e-19 70.5 26.9 1.9e-10 40.1 0.2 2.1 1 1 0 2 2 2 2 Dynactin p62 family MANEC PF07502.9 AET39556.1 - 0.017 15.1 8.0 0.017 15.1 5.6 1.7 2 0 0 2 2 2 0 MANEC domain zf-Mss51 PF13824.1 AET39556.1 - 0.15 11.9 11.9 0.21 11.4 5.1 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Elf1 PF05129.8 AET39556.1 - 1.8 8.3 19.1 0.18 11.5 3.8 3.1 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like CENP-X PF09415.5 AET39557.1 - 8.3e-26 89.6 0.0 9.4e-26 89.4 0.0 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X MMR_HSR1 PF01926.18 AET39558.1 - 4.1e-21 75.1 0.6 1.5e-20 73.3 0.4 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 AET39558.1 - 1e-19 70.0 0.0 2.3e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 AET39558.1 - 1.2e-15 57.1 0.0 2.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AET39558.1 - 5.7e-06 26.2 0.8 0.00094 19.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 AET39558.1 - 2.8e-05 24.6 0.3 0.0001 22.7 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 AET39558.1 - 0.0011 18.1 0.1 0.0019 17.3 0.1 1.4 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 AET39558.1 - 0.0019 17.4 0.7 0.0083 15.3 0.1 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MCM PF00493.18 AET39558.1 - 0.0031 16.3 0.1 0.0067 15.2 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family GTP_EFTU PF00009.22 AET39558.1 - 0.011 15.2 1.0 1.2 8.5 0.2 3.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.17 AET39558.1 - 0.021 14.2 0.3 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_28 PF13521.1 AET39558.1 - 0.14 12.0 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Yip1 PF04893.12 AET39559.1 - 1.8e-07 30.7 17.6 4e-05 23.1 8.3 2.2 2 0 0 2 2 2 2 Yip1 domain Pkinase PF00069.20 AET39560.1 - 1.6e-66 224.1 0.0 2.5e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39560.1 - 1.4e-29 102.9 0.0 2.3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET39560.1 - 4.4e-07 29.1 0.0 1.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AET39560.1 - 0.00018 21.3 0.0 0.0028 17.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AET39560.1 - 0.0079 15.2 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PASTA PF03793.14 AET39560.1 - 0.15 11.6 1.0 0.41 10.3 0.7 1.7 1 0 0 1 1 1 0 PASTA domain DAO PF01266.19 AET39561.1 - 2e-69 234.2 0.0 2.7e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AET39561.1 - 4.2e-07 29.8 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AET39561.1 - 0.00058 19.0 0.1 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 AET39561.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AET39561.1 - 0.0081 16.2 0.0 0.42 10.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 AET39561.1 - 0.013 14.4 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Strep_67kDa_ant PF06100.6 AET39561.1 - 0.024 13.0 0.2 0.042 12.2 0.1 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Trp_halogenase PF04820.9 AET39561.1 - 0.066 11.8 0.1 0.11 11.1 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 AET39561.1 - 0.11 12.8 0.1 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AET39561.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain SNARE PF05739.14 AET39562.1 - 1.5e-10 40.5 2.5 1.5e-10 40.5 1.7 3.2 4 0 0 4 4 4 1 SNARE domain Syntaxin-6_N PF09177.6 AET39562.1 - 4.7e-06 26.9 11.7 3.6e-05 24.0 5.1 3.0 2 1 0 2 2 2 1 Syntaxin 6, N-terminal Use1 PF09753.4 AET39562.1 - 0.0022 17.4 5.2 0.0034 16.8 3.6 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Vezatin PF12632.2 AET39562.1 - 0.008 15.2 1.8 0.008 15.2 1.2 1.8 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes DUF2400 PF09674.5 AET39562.1 - 0.0083 15.8 1.8 0.017 14.8 1.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2400) Nup88 PF10168.4 AET39562.1 - 0.013 13.4 11.6 0.014 13.3 0.2 2.0 1 1 1 2 2 2 0 Nuclear pore component AAA_13 PF13166.1 AET39562.1 - 0.018 13.5 8.1 0.025 13.0 5.6 1.2 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 AET39562.1 - 0.033 13.9 7.8 1.4 8.7 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Reprolysin PF01421.14 AET39562.1 - 0.044 13.3 1.5 0.061 12.8 1.0 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease BLUF PF04940.7 AET39562.1 - 0.047 13.4 2.2 2.2 8.0 0.1 2.5 2 0 0 2 2 2 0 Sensors of blue-light using FAD Sec20 PF03908.8 AET39562.1 - 0.056 13.1 0.2 0.056 13.1 0.1 2.8 2 1 1 3 3 3 0 Sec20 IL2 PF00715.12 AET39562.1 - 0.063 12.9 4.0 1.3 8.7 1.3 2.3 1 1 0 2 2 2 0 Interleukin 2 DUF4201 PF13870.1 AET39562.1 - 0.081 12.3 13.6 1.4 8.3 4.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4635 PF15466.1 AET39562.1 - 0.083 12.1 5.3 1 8.6 1.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4635) TMPIT PF07851.8 AET39562.1 - 0.11 11.4 5.1 0.29 10.1 0.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein Vps5 PF09325.5 AET39562.1 - 0.12 11.5 13.2 0.83 8.8 0.6 2.1 1 1 1 2 2 2 0 Vps5 C terminal like Laminin_II PF06009.7 AET39562.1 - 0.15 11.8 10.1 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF4164 PF13747.1 AET39562.1 - 0.17 12.0 12.6 0.9 9.7 1.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Spc7 PF08317.6 AET39562.1 - 0.19 10.3 16.8 0.77 8.3 7.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cluap1 PF10234.4 AET39562.1 - 0.34 10.0 12.1 1.2 8.2 4.9 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 Troponin PF00992.15 AET39562.1 - 0.35 10.9 6.9 0.11 12.5 2.4 1.8 2 0 0 2 2 2 0 Troponin Sec5 PF15469.1 AET39562.1 - 0.43 10.2 5.3 3.6 7.2 1.1 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 Cytochrom_B562 PF07361.6 AET39562.1 - 0.46 10.9 6.2 4.3 7.8 1.3 2.5 2 1 0 2 2 2 0 Cytochrome b562 Reo_sigmaC PF04582.7 AET39562.1 - 0.62 9.1 8.9 4 6.5 2.5 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Occludin_ELL PF07303.8 AET39562.1 - 0.77 10.5 7.7 14 6.4 2.0 3.4 2 2 0 2 2 2 0 Occludin homology domain DUF3573 PF12097.3 AET39562.1 - 0.78 8.2 5.6 1.1 7.8 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Baculo_PEP_C PF04513.7 AET39562.1 - 1 9.1 10.4 1.7e+02 2.0 7.3 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cortex-I_coil PF09304.5 AET39562.1 - 1.1 9.3 13.7 2.2 8.3 1.6 2.8 1 1 2 3 3 3 0 Cortexillin I, coiled coil BLOC1_2 PF10046.4 AET39562.1 - 1.3 9.1 10.6 0.64 10.1 1.8 2.9 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 AET39562.1 - 1.4 8.9 11.1 25 4.8 0.0 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) COG6 PF06419.6 AET39562.1 - 1.6 6.8 12.7 0.37 8.8 4.5 2.0 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 PspA_IM30 PF04012.7 AET39562.1 - 1.7 7.9 11.2 0.92 8.8 0.1 2.8 2 1 1 3 3 3 0 PspA/IM30 family WXG100 PF06013.7 AET39562.1 - 1.9 8.5 9.9 32 4.6 1.5 3.6 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Hpt PF01627.18 AET39562.1 - 2 8.4 6.5 1.2 9.1 0.3 2.6 2 0 0 2 2 2 0 Hpt domain Tweety PF04906.8 AET39562.1 - 2 6.7 8.1 0.23 9.8 0.2 2.4 2 1 0 2 2 2 0 Tweety DUF745 PF05335.8 AET39562.1 - 2.3 7.6 10.7 11 5.5 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) EAP30 PF04157.11 AET39562.1 - 2.9 6.9 10.0 2.2 7.3 2.0 2.3 2 1 0 2 2 2 0 EAP30/Vps36 family DUF1342 PF07072.6 AET39562.1 - 3.2 7.3 8.6 4.5 6.8 0.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1342) DUF1640 PF07798.6 AET39562.1 - 3.3 7.7 13.9 0.59 10.1 0.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) ING PF12998.2 AET39562.1 - 3.8 7.8 11.4 1.8 8.8 5.0 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Cep57_CLD_2 PF14197.1 AET39562.1 - 3.8 7.5 15.3 1 9.3 4.1 3.5 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 FliJ PF02050.11 AET39562.1 - 4 7.5 17.7 3.9 7.5 1.7 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein EntA_Immun PF08951.5 AET39562.1 - 4.1 7.6 9.1 14 5.9 2.5 2.9 2 1 0 2 2 2 0 Enterocin A Immunity DUF972 PF06156.8 AET39562.1 - 4.3 7.7 12.4 21 5.4 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) TBPIP PF07106.8 AET39562.1 - 4.8 6.7 15.6 8.4 5.9 6.7 2.4 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_p24 PF05073.7 AET39562.1 - 4.9 6.6 8.9 5.1 6.6 1.9 2.1 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Enkurin PF13864.1 AET39562.1 - 5.6 7.2 7.3 2.1 8.5 0.7 2.6 3 0 0 3 3 2 0 Calmodulin-binding Spectrin PF00435.16 AET39562.1 - 6.1 7.1 12.4 18 5.6 1.7 2.5 1 1 1 2 2 2 0 Spectrin repeat Hrs_helical PF12210.3 AET39562.1 - 7.9 6.8 11.8 4.2 7.6 0.3 3.0 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Phage_GPO PF05929.6 AET39562.1 - 7.9 5.6 9.9 1.2 8.3 2.7 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2524 PF10732.4 AET39562.1 - 9 6.4 13.9 0.23 11.6 0.4 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF2524) Atg14 PF10186.4 AET39562.1 - 9.1 5.1 13.2 12 4.6 8.3 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PhoU PF01895.14 AET39562.1 - 9.7 6.7 9.3 35 4.9 0.1 2.6 1 1 1 2 2 2 0 PhoU domain Fib_alpha PF08702.5 AET39562.1 - 9.9 6.2 13.1 10 6.2 1.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Dpy-30 PF05186.8 AET39563.1 - 2e-14 52.8 0.0 2.6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Mito_carr PF00153.22 AET39564.1 - 3.7e-12 45.7 0.0 0.0012 18.4 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein GCR1_C PF12550.3 AET39564.1 - 0.096 12.5 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes IncA PF04156.9 AET39565.1 - 0.00068 19.2 6.3 0.00068 19.2 4.4 2.1 1 1 1 2 2 2 2 IncA protein DUF2151 PF10221.4 AET39565.1 - 0.014 13.6 6.3 0.017 13.3 4.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Laminin_II PF06009.7 AET39565.1 - 0.041 13.6 13.5 0.68 9.6 0.5 2.6 2 1 0 2 2 2 0 Laminin Domain II DUF3734 PF12536.3 AET39565.1 - 0.2 11.8 2.2 0.6 10.2 0.9 2.2 1 1 1 2 2 2 0 Patatin phospholipase Seryl_tRNA_N PF02403.17 AET39565.1 - 1.7 8.7 16.6 3.1 7.8 3.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 AET39565.1 - 4.7 7.3 12.0 6.5 6.8 3.1 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 AET39565.1 - 6.3 7.1 11.6 8 6.8 2.3 4.0 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.3 AET39565.1 - 6.5 6.5 22.0 6.9 6.4 3.1 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.6 AET39565.1 - 9.6 6.0 11.3 1.4 8.7 2.5 2.7 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_L27e PF01777.13 AET39566.1 - 3.3e-36 123.2 6.2 4.5e-36 122.8 4.3 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 AET39566.1 - 0.0013 18.4 1.0 0.0025 17.4 0.7 1.6 1 0 0 1 1 1 1 KOW motif DUF1512 PF07431.7 AET39566.1 - 0.08 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) tRNA-synt_2b PF00587.20 AET39567.1 - 3.3e-25 88.6 0.0 1.4e-24 86.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AET39567.1 - 7.1e-05 22.7 8.9 0.00013 21.9 6.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 AET39567.1 - 0.007 14.2 3.3 0.0093 13.8 2.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Pex19 PF04614.7 AET39567.1 - 0.014 15.0 2.9 0.022 14.4 2.0 1.2 1 0 0 1 1 1 0 Pex19 protein family GAS PF13851.1 AET39567.1 - 0.025 13.7 7.9 0.056 12.6 5.5 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 AET39567.1 - 0.037 12.4 2.5 0.13 10.6 2.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF2262 PF10020.4 AET39567.1 - 0.062 13.5 1.1 0.16 12.1 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) Rbsn PF11464.3 AET39567.1 - 0.077 12.5 2.3 5.6 6.6 0.1 2.5 2 0 0 2 2 2 0 Rabenosyn Rab binding domain IncA PF04156.9 AET39567.1 - 0.13 11.8 8.2 0.24 10.9 5.7 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 AET39567.1 - 0.19 10.7 8.5 0.32 10.0 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2400 PF09674.5 AET39567.1 - 0.4 10.3 3.3 0.87 9.2 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) SseC PF04888.7 AET39567.1 - 1.1 8.5 5.6 1.6 8.0 3.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Metallophos_2 PF12850.2 AET39568.1 - 1.6e-12 47.5 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acetyltransf_1 PF00583.19 AET39569.1 - 1.1e-15 57.4 0.0 1.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AET39569.1 - 1.9e-05 24.3 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 AET39569.1 - 3.3e-05 23.9 0.0 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AET39569.1 - 9.7e-05 22.4 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AET39569.1 - 0.0096 15.7 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AET39569.1 - 0.087 12.7 0.0 0.37 10.7 0.0 2.1 2 1 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 AET39569.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TRAPP PF04051.11 AET39570.1 - 3.9e-46 156.3 0.0 4.7e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_L23 PF00276.15 AET39573.1 - 7.2e-23 80.3 0.0 1.6e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpb2_6 PF00562.23 AET39574.1 - 1e-124 416.2 0.1 1.6e-124 415.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AET39574.1 - 5.1e-68 228.0 0.1 8e-68 227.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AET39574.1 - 1.5e-51 174.5 0.0 2.6e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 AET39574.1 - 1.2e-30 105.6 0.1 3e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 AET39574.1 - 2.7e-27 94.3 0.8 6e-27 93.2 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 AET39574.1 - 6.4e-22 77.0 0.1 1.8e-21 75.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 AET39574.1 - 3.1e-18 65.4 0.8 8.1e-18 64.1 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L13 PF00572.13 AET39575.1 - 1.7e-44 150.9 0.1 2e-44 150.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 SHS2_Rpb7-N PF03876.12 AET39576.1 - 2.8e-18 65.7 0.0 4.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AET39576.1 - 7.4e-12 45.1 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 AET39576.1 - 0.00037 20.6 0.0 0.00076 19.6 0.0 1.5 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 DIT1_PvcA PF05141.7 AET39577.1 - 6.8e-105 350.3 0.0 8.8e-105 349.9 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Spt4 PF06093.8 AET39577.1 - 0.12 12.2 0.1 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger IU_nuc_hydro PF01156.14 AET39578.1 - 7.7e-71 238.8 0.0 8.7e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Utp12 PF04003.7 AET39579.1 - 2.9e-18 65.7 2.0 5.5e-18 64.8 1.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family CBFD_NFYB_HMF PF00808.18 AET39580.1 - 4.6e-14 52.2 1.5 8.1e-14 51.4 1.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hydrolase_like PF13242.1 AET39580.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like IBN_N PF03810.14 AET39581.1 - 1.7e-11 43.8 1.5 4.5e-11 42.5 0.4 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Telomerase_RBD PF12009.3 AET39581.1 - 0.0016 18.3 0.4 0.005 16.7 0.3 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain DUF445 PF04286.7 AET39581.1 - 0.12 11.9 2.3 0.42 10.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF445) TetR_C_8 PF14278.1 AET39581.1 - 0.83 10.0 11.4 3.6 8.0 0.2 4.7 3 1 1 4 4 4 0 Transcriptional regulator C-terminal region Glyco_transf_22 PF03901.12 AET39582.1 - 4.9e-59 200.4 20.0 4.9e-59 200.4 13.9 1.3 2 0 0 2 2 2 1 Alg9-like mannosyltransferase family AAA PF00004.24 AET39583.1 - 2.6e-46 157.0 0.0 7.5e-46 155.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AET39583.1 - 2.5e-08 34.0 0.0 4.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AET39583.1 - 6.3e-08 32.4 0.1 2.5e-07 30.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AET39583.1 - 2.4e-07 30.9 0.1 9.7e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AET39583.1 - 1.1e-06 28.8 0.4 8.3e-05 22.7 0.3 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 AET39583.1 - 6.3e-05 22.0 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 AET39583.1 - 0.00014 22.6 0.2 0.00051 20.8 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AET39583.1 - 0.0003 20.6 0.0 0.00076 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AET39583.1 - 0.00034 19.7 0.0 0.00083 18.4 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 AET39583.1 - 0.00096 18.8 0.0 0.0029 17.3 0.0 1.8 2 0 0 2 2 1 1 NTPase AAA_19 PF13245.1 AET39583.1 - 0.0014 18.3 0.1 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 AET39583.1 - 0.0016 17.2 0.0 0.0028 16.4 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 AET39583.1 - 0.0016 18.5 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 AET39583.1 - 0.0018 17.3 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 AET39583.1 - 0.0027 17.3 0.0 0.0074 15.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 AET39583.1 - 0.0032 17.0 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AET39583.1 - 0.0033 17.4 0.0 0.0089 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AET39583.1 - 0.0036 16.9 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AET39583.1 - 0.0037 17.1 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 AET39583.1 - 0.0038 16.7 0.0 0.15 11.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 AET39583.1 - 0.0042 16.7 0.1 0.061 12.9 0.0 2.4 1 1 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 AET39583.1 - 0.0045 16.4 0.9 0.11 11.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.1 AET39583.1 - 0.0047 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 AET39583.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 AET39583.1 - 0.0063 15.7 0.1 0.015 14.4 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AET39583.1 - 0.013 15.2 0.5 0.15 11.7 0.0 2.5 2 1 0 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 AET39583.1 - 0.014 14.7 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 AET39583.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AET39583.1 - 0.038 14.3 0.1 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 AET39583.1 - 0.063 12.9 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein NB-ARC PF00931.17 AET39583.1 - 0.098 11.4 0.0 0.24 10.2 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain She9_MDM33 PF05546.6 AET39584.1 - 1.4e-88 295.9 15.1 1.4e-88 295.9 10.5 1.8 2 0 0 2 2 2 1 She9 / Mdm33 family DUF1395 PF07160.7 AET39584.1 - 0.013 15.0 23.3 0.089 12.2 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1395) DUF4206 PF13901.1 AET39584.1 - 0.077 12.5 1.0 0.2 11.1 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) PsbH PF00737.15 AET39584.1 - 0.1 12.2 0.4 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein G-patch_2 PF12656.2 AET39585.1 - 3.1e-20 71.8 1.8 8e-20 70.4 0.2 2.1 2 0 0 2 2 2 1 DExH-box splicing factor binding site MDM31_MDM32 PF08118.6 AET39586.1 - 2.8e-76 257.0 13.4 6.8e-35 120.4 0.6 4.1 2 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 AET39587.1 - 0.00024 20.6 0.7 0.00051 19.6 0.5 1.5 1 0 0 1 1 1 1 KH domain DUF3979 PF13141.1 AET39587.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) AAA PF00004.24 AET39588.1 - 3.1e-06 27.4 0.6 0.00019 21.6 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) HTH_Tnp_Tc3_1 PF11427.3 AET39588.1 - 0.018 14.6 0.1 0.088 12.4 0.0 2.1 2 0 0 2 2 2 0 Tc3 transposase TFIID-18kDa PF02269.11 AET39589.1 - 2.6e-36 123.2 0.4 1.5e-35 120.8 0.1 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Ribosomal_60s PF00428.14 AET39589.1 - 0.028 14.7 0.6 0.074 13.4 0.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein TPK_catalytic PF04263.11 AET39590.1 - 6.4e-20 70.9 0.0 7.6e-16 57.8 0.0 2.4 1 1 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 AET39590.1 - 2.5e-13 49.5 0.1 7.4e-13 48.0 0.0 1.9 1 1 1 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Ligase_CoA PF00549.14 AET39591.1 - 8.8e-25 87.0 0.8 1.4e-24 86.4 0.6 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 AET39591.1 - 1.2e-24 86.6 3.3 4.2e-24 84.8 0.6 2.2 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 AET39591.1 - 3.9e-10 39.4 0.1 6.8e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AET39591.1 - 6.5e-06 26.2 0.1 5.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain DASH_Ask1 PF08655.5 AET39592.1 - 3.5e-30 103.6 2.1 3.8e-30 103.4 0.5 1.8 2 0 0 2 2 2 1 DASH complex subunit Ask1 UPF0203 PF05254.7 AET39593.1 - 4.7e-30 103.2 2.2 5.4e-30 103.0 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 AET39593.1 - 0.00038 20.1 1.9 0.12 12.1 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 AET39593.1 - 0.0062 16.4 3.2 0.064 13.1 2.2 2.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 AET39593.1 - 0.038 13.9 3.9 0.16 11.8 0.5 2.2 2 0 0 2 2 2 0 CHCH domain Mvb12 PF09452.5 AET39593.1 - 0.21 11.8 0.7 0.34 11.1 0.2 1.5 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 Pet191_N PF10203.4 AET39593.1 - 0.62 10.1 2.9 2.6 8.1 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 adh_short PF00106.20 AET39594.1 - 5.3e-13 49.2 0.0 7e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 AET39594.1 - 0.00086 19.1 0.1 0.021 14.5 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 AET39594.1 - 0.0068 15.3 0.1 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 AET39594.1 - 0.015 14.9 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.1 AET39594.1 - 0.052 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 AET39594.1 - 0.089 12.2 0.4 2.6 7.3 0.0 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family TCTP PF00838.12 AET39595.1 - 1.2e-72 243.2 1.4 1.3e-72 243.1 1.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Striatin PF08232.7 AET39596.1 - 3.5e-26 92.1 9.7 2.4e-24 86.1 0.9 3.2 2 1 1 3 3 3 2 Striatin family TPR_3 PF07720.7 AET39597.1 - 0.025 14.3 0.1 0.14 11.9 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TAP42 PF04177.7 AET39598.1 - 1.8e-89 300.0 10.3 2e-89 299.9 7.1 1.0 1 0 0 1 1 1 1 TAP42-like family TFIIA_gamma_C PF02751.9 AET39599.1 - 7.6e-27 92.8 1.5 1.1e-26 92.3 1.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 AET39599.1 - 3.1e-24 84.2 0.2 4.3e-24 83.8 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DWNN PF08783.6 AET39600.1 - 7.7e-31 105.8 0.4 1.8e-30 104.7 0.0 1.8 2 0 0 2 2 2 1 DWNN domain U-box PF04564.10 AET39600.1 - 0.00041 20.2 0.0 0.0051 16.7 0.0 2.4 2 0 0 2 2 2 1 U-box domain zf-CCHC_2 PF13696.1 AET39600.1 - 0.00097 18.5 4.1 0.002 17.5 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 AET39600.1 - 0.0038 17.1 4.1 0.0038 17.1 2.8 1.7 2 0 0 2 2 2 1 Zinc knuckle Rubredoxin PF00301.15 AET39600.1 - 0.0062 16.3 3.6 0.46 10.3 0.0 2.9 3 0 0 3 3 3 2 Rubredoxin zf-CCHC_3 PF13917.1 AET39600.1 - 0.016 14.9 0.1 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Telomere_Sde2_2 PF13297.1 AET39600.1 - 0.062 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Telomere stability C-terminal zf-Nse PF11789.3 AET39600.1 - 0.085 12.3 0.2 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Gly-zipper_OmpA PF13436.1 AET39600.1 - 1.5 8.4 12.8 0.74 9.4 1.6 2.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF89 PF01937.14 AET39601.1 - 1.5e-113 379.2 0.0 1.7e-113 379.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 F_bP_aldolase PF01116.15 AET39602.1 - 4.9e-96 321.2 0.1 5.5e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_C26 PF07722.8 AET39602.1 - 0.11 11.9 0.0 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase C26 Pex2_Pex12 PF04757.9 AET39603.1 - 7.8e-34 117.0 4.6 1.1e-33 116.6 3.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 AET39603.1 - 6.2e-07 29.3 1.4 1e-06 28.6 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AET39603.1 - 0.00026 20.5 0.4 0.00044 19.8 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AET39603.1 - 0.067 13.0 4.0 0.11 12.3 2.8 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AET39603.1 - 0.073 12.7 0.6 0.12 12.0 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET39603.1 - 0.11 12.3 0.9 0.2 11.5 0.6 1.4 1 0 0 1 1 1 0 Ring finger domain SNARE PF05739.14 AET39604.1 - 0.0075 15.9 0.2 0.17 11.5 0.0 2.2 2 0 0 2 2 2 1 SNARE domain MitMem_reg PF13012.1 AET39604.1 - 0.098 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Ribonuclease_3 PF00636.21 AET39605.1 - 9.3e-09 35.7 0.0 1.8e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 AET39605.1 - 2.1e-07 31.4 0.0 4.1e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif PUL PF08324.6 AET39605.1 - 0.044 12.5 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 PUL domain TrmE_N PF10396.4 AET39607.1 - 3.7e-35 120.3 0.0 7.8e-35 119.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 AET39607.1 - 8.3e-23 80.5 0.8 8.3e-23 80.5 0.6 1.8 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 AET39607.1 - 6.3e-17 61.7 0.0 1.8e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 AET39607.1 - 3.3e-14 52.4 1.9 3.7e-14 52.3 0.7 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Ras PF00071.17 AET39607.1 - 1.3e-06 27.8 0.0 3.5e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Ras family Arf PF00025.16 AET39607.1 - 2.8e-06 26.6 0.8 4.7e-05 22.7 0.6 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AET39607.1 - 4.3e-06 26.3 0.3 0.0005 19.5 0.2 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AET39607.1 - 1.2e-05 25.2 2.0 0.0029 17.4 0.1 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 AET39607.1 - 2.9e-05 24.5 0.0 7.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AET39607.1 - 6.4e-05 22.4 0.1 0.0074 15.7 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 AET39607.1 - 0.0018 18.4 0.5 0.011 15.9 0.1 2.5 2 1 1 3 3 3 1 AAA domain AIG1 PF04548.11 AET39607.1 - 0.0021 17.1 0.3 0.0039 16.3 0.2 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 AET39607.1 - 0.0049 16.0 0.1 0.011 14.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 AET39607.1 - 0.0074 15.3 1.2 0.51 9.3 0.5 2.3 1 1 1 2 2 2 1 Septin AAA_10 PF12846.2 AET39607.1 - 0.0083 15.5 0.1 0.5 9.7 0.0 2.7 2 1 0 2 2 2 1 AAA-like domain cobW PF02492.14 AET39607.1 - 0.0099 15.3 1.5 2.4 7.5 0.1 2.5 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 AET39607.1 - 0.013 15.7 1.1 0.031 14.5 0.8 1.8 1 1 0 1 1 1 0 ABC transporter BLOC1_2 PF10046.4 AET39608.1 - 0.0019 18.3 0.9 0.0034 17.4 0.3 1.7 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2347 PF09804.4 AET39609.1 - 8.7e-75 251.5 0.1 1.2e-74 251.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 AET39609.1 - 3.9e-21 75.9 2.8 2.8e-11 43.8 0.5 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.4 AET39609.1 - 1.3e-06 27.2 0.0 0.00043 18.8 0.0 2.8 3 0 0 3 3 3 2 Transport protein Avl9 SPA PF08616.5 AET39609.1 - 0.004 16.8 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis DUF1798 PF08807.5 AET39609.1 - 0.11 12.1 0.2 0.35 10.6 0.1 1.8 1 1 1 2 2 2 0 Bacterial domain of unknown function (DUF1798) Glyco_hydro_76 PF03663.9 AET39610.1 - 8.4e-145 482.7 11.8 1.1e-144 482.3 8.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 UQ_con PF00179.21 AET39611.1 - 2.9e-48 162.8 0.0 3.2e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AET39611.1 - 0.08 12.6 0.1 0.38 10.5 0.0 2.1 1 1 1 2 2 2 0 Prokaryotic E2 family B RWD PF05773.17 AET39611.1 - 0.21 11.5 1.4 0.48 10.3 1.0 1.9 1 1 0 1 1 1 0 RWD domain Copper-fist PF00649.13 AET39612.1 - 1.1e-21 75.7 2.8 1.1e-21 75.7 1.9 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain MRI PF15325.1 AET39612.1 - 0.047 14.6 0.1 0.047 14.6 0.0 2.6 3 0 0 3 3 3 0 Modulator of retrovirus infection Amino_oxidase PF01593.19 AET39613.1 - 4.1e-50 171.1 0.0 1.1e-32 113.7 0.0 2.9 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 AET39613.1 - 7.3e-10 38.7 0.1 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AET39613.1 - 5.4e-07 29.8 0.1 0.0011 19.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AET39613.1 - 6e-07 28.6 0.1 0.00079 18.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AET39613.1 - 0.0011 18.1 0.1 0.002 17.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 AET39613.1 - 0.0043 15.9 0.4 0.0089 14.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 AET39613.1 - 0.027 14.2 0.4 5.8 6.6 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 AET39613.1 - 0.035 14.5 0.7 0.6 10.5 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AET39613.1 - 0.038 13.8 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AET39613.1 - 0.11 11.6 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 AET39613.1 - 0.12 11.3 0.7 1.9 7.3 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DNA_primase_lrg PF04104.9 AET39614.1 - 1.2e-76 257.4 0.0 1.9e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit KilA-N PF04383.8 AET39617.1 - 6.1e-05 22.6 0.0 0.00056 19.5 0.0 2.5 1 1 0 1 1 1 1 KilA-N domain Mitofilin PF09731.4 AET39617.1 - 0.0021 16.7 14.9 0.0021 16.7 10.4 3.2 3 0 0 3 3 3 2 Mitochondrial inner membrane protein Spc42p PF11544.3 AET39618.1 - 1.2e-20 73.2 13.3 1.2e-20 73.2 9.2 4.2 2 1 1 4 4 4 1 Spindle pole body component Spc42p PhoU PF01895.14 AET39618.1 - 0.014 15.7 5.1 12 6.3 0.1 3.2 3 0 0 3 3 3 0 PhoU domain DivIVA PF05103.8 AET39618.1 - 0.021 14.8 20.7 0.058 13.4 4.1 2.4 1 1 1 2 2 2 0 DivIVA protein BUD22 PF09073.5 AET39619.1 - 4.9e-91 305.9 31.7 7.5e-91 305.3 22.0 1.3 1 0 0 1 1 1 1 BUD22 Phycoerythr_ab PF02972.9 AET39619.1 - 0.1 12.1 0.9 9.2 5.9 0.1 2.9 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain CTP_transf_1 PF01148.15 AET39620.1 - 9.2e-08 32.0 1.8 9.2e-08 32.0 1.3 4.4 2 2 1 4 4 4 2 Cytidylyltransferase family Snf7 PF03357.16 AET39621.1 - 7.2e-27 93.8 28.4 3e-26 91.8 19.7 1.8 1 1 0 1 1 1 1 Snf7 PAS_7 PF12860.2 AET39621.1 - 0.011 15.7 3.8 0.49 10.4 0.1 2.8 1 1 2 3 3 3 0 PAS fold SpecificRecomb PF10136.4 AET39621.1 - 2 6.3 7.4 0.67 7.9 3.2 1.5 1 1 1 2 2 2 0 Site-specific recombinase Opi1 PF08618.5 AET39622.1 - 3.9e-40 138.0 6.7 2.4e-27 95.9 1.1 3.1 2 1 1 3 3 3 3 Transcription factor Opi1 SF-assemblin PF06705.6 AET39622.1 - 0.00033 19.8 3.8 0.00033 19.8 2.6 1.8 2 0 0 2 2 2 1 SF-assemblin/beta giardin DUF4615 PF15393.1 AET39622.1 - 0.042 14.0 1.0 0.042 14.0 0.7 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4615) Adap_comp_sub PF00928.16 AET39623.1 - 1.3e-56 191.6 0.2 1.7e-56 191.2 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pterin_4a PF01329.14 AET39624.1 - 9.9e-27 92.5 0.0 1.2e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Nfu_N PF08712.6 AET39625.1 - 1.8e-24 85.1 0.1 7e-24 83.2 0.0 2.0 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 AET39625.1 - 2.5e-22 78.4 0.0 4.1e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 AET39625.1 - 0.015 15.1 3.3 0.028 14.2 2.3 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Lung_7-TM_R PF06814.8 AET39626.1 - 1.3e-66 224.5 19.2 1.7e-66 224.1 13.3 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Mtc PF03820.12 AET39626.1 - 0.0049 15.5 0.1 0.012 14.3 0.1 1.6 1 0 0 1 1 1 1 Tricarboxylate carrier SSF PF00474.12 AET39627.1 - 1.4e-16 60.2 32.2 1.4e-16 60.2 22.4 2.0 2 0 0 2 2 2 1 Sodium:solute symporter family Ribosomal_S10 PF00338.17 AET39628.1 - 1.3e-26 92.2 0.5 1.5e-26 92.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Retrotrans_gag PF03732.12 AET39628.1 - 0.039 14.0 0.0 0.065 13.3 0.0 1.5 1 1 0 1 1 1 0 Retrotransposon gag protein RII_binding_1 PF10522.4 AET39628.1 - 0.11 12.6 0.3 32 5.1 0.0 2.6 2 0 0 2 2 2 0 RII binding domain YchF-GTPase_C PF06071.8 AET39629.1 - 1.2e-30 105.0 0.0 2.7e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 AET39629.1 - 3.3e-13 49.6 0.0 7.1e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AET39629.1 - 0.00025 20.3 0.0 0.00047 19.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 AET39629.1 - 0.0094 15.7 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain OTU PF02338.14 AET39630.1 - 6.2e-18 65.5 1.3 3e-17 63.3 0.1 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 AET39630.1 - 0.0017 17.7 0.8 0.55 9.5 0.0 2.9 3 0 0 3 3 3 2 Peptidase C65 Otubain DUF603 PF04645.7 AET39630.1 - 0.11 12.3 1.5 0.27 11.1 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF603 GlutR_dimer PF00745.15 AET39630.1 - 3.7 7.5 8.3 0.58 10.1 0.8 2.5 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain RPM2 PF08579.6 AET39632.1 - 1.6e-45 154.0 6.6 5.6e-45 152.3 0.6 3.3 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.1 AET39632.1 - 2.3e-05 24.2 0.1 0.45 10.5 0.0 4.6 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.15 AET39632.1 - 0.014 15.3 0.1 0.23 11.4 0.0 3.3 2 0 0 2 2 2 0 PPR repeat RST PF12174.3 AET39632.1 - 0.019 14.7 0.8 18 5.2 0.0 3.8 2 1 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain PPR_3 PF13812.1 AET39632.1 - 0.029 14.6 0.1 7 7.2 0.0 4.6 5 0 0 5 5 5 0 Pentatricopeptide repeat domain HMG_CoA_synt_C PF08540.5 AET39633.1 - 2.3e-106 355.4 0.7 2.7e-106 355.1 0.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 AET39633.1 - 3.2e-93 310.0 0.3 4.5e-93 309.6 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Ubie_methyltran PF01209.13 AET39634.1 - 3.4e-91 304.4 0.1 4e-91 304.2 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 AET39634.1 - 7e-12 45.1 0.0 2.4e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AET39634.1 - 1.3e-08 35.1 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AET39634.1 - 4e-08 33.6 0.0 6.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AET39634.1 - 8.1e-07 29.3 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AET39634.1 - 1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET39634.1 - 0.0001 22.8 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET39634.1 - 0.019 15.0 0.0 0.14 12.1 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.10 AET39634.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase CTK3_C PF12350.3 AET39635.1 - 3.5e-20 71.7 5.6 8.5e-20 70.5 3.9 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 AET39635.1 - 1.1e-07 31.5 0.1 5.5e-07 29.2 0.1 2.1 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 XPG_N PF00752.12 AET39635.1 - 0.044 14.0 0.3 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 XPG N-terminal domain ubiquitin PF00240.18 AET39637.1 - 2.2e-20 71.8 0.0 3.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AET39637.1 - 8.8e-11 41.3 0.0 1.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 AET39637.1 - 4.1e-07 29.6 0.1 1.1e-06 28.3 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_2 PF14560.1 AET39637.1 - 0.00031 20.9 0.1 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 AET39637.1 - 0.0074 16.1 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AET39637.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TAF8_C PF10406.4 AET39638.1 - 8.3e-22 76.9 0.2 2.8e-21 75.3 0.2 2.0 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term OST-HTH PF12872.2 AET39638.1 - 0.0099 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 OST-HTH/LOTUS domain PGA2 PF07543.7 AET39638.1 - 0.064 13.0 0.3 0.064 13.0 0.2 2.3 2 1 1 3 3 3 0 Protein trafficking PGA2 NIF PF03031.13 AET39639.1 - 1.4e-23 83.3 0.6 5.3e-23 81.4 0.0 2.4 2 1 1 3 3 3 1 NLI interacting factor-like phosphatase BRCT PF00533.21 AET39639.1 - 2.6e-12 46.6 1.3 6.4e-12 45.4 0.2 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AET39639.1 - 6.6e-07 29.0 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl_2 PF13533.1 AET39639.1 - 8.2e-05 22.1 0.0 0.059 13.0 0.0 2.6 2 0 0 2 2 2 2 Biotin-lipoyl like PGM_PMM_I PF02878.11 AET39640.1 - 1.7e-38 131.1 0.1 4.2e-38 129.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AET39640.1 - 3.2e-19 69.1 0.0 7.9e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 AET39640.1 - 1.5e-14 53.9 0.0 2.8e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 AET39640.1 - 4.3e-06 26.6 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain S-methyl_trans PF02574.11 AET39641.1 - 7.2e-84 281.6 0.0 8.1e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Anp1 PF03452.9 AET39642.1 - 5.3e-122 406.1 0.1 7.4e-122 405.6 0.0 1.2 1 0 0 1 1 1 1 Anp1 Asp PF00026.18 AET39643.1 - 1.6e-44 152.4 0.9 2.1e-44 152.0 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AET39643.1 - 6.7e-09 35.8 0.0 1.8e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AET39643.1 - 1.9e-06 27.4 0.0 6.3e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Nab6_mRNP_bdg PF10567.4 AET39644.1 - 4.6e-94 314.8 7.8 1.1e-93 313.6 5.4 1.7 1 0 0 1 1 1 1 RNA-recognition motif RRM PF10378.4 AET39644.1 - 4.9e-22 77.2 10.3 1.8e-21 75.4 7.1 2.0 1 0 0 1 1 1 1 Putative RRM domain RRM_6 PF14259.1 AET39644.1 - 1e-09 38.1 0.1 8.4e-05 22.4 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET39644.1 - 3.6e-08 33.1 0.1 0.0021 17.8 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET39644.1 - 4.3e-06 26.2 0.0 0.022 14.4 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 AET39645.1 - 1.4e-36 125.7 0.5 2.6e-36 124.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET39645.1 - 1.7e-10 40.6 13.0 3.1e-10 39.7 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIG-L PF02585.12 AET39646.1 - 1.3e-24 87.1 0.2 2e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.2 AET39647.1 - 2.5e-27 94.7 0.2 8.7e-27 92.9 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATPase expression EutB PF06751.6 AET39647.1 - 0.047 12.0 0.0 0.12 10.7 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine ammonia lyase large subunit (EutB) BaffR-Tall_bind PF09256.5 AET39647.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Exo_endo_phos PF03372.18 AET39648.1 - 5.5e-20 72.3 0.1 7.6e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ku PF02735.11 AET39649.1 - 1e-28 100.1 0.1 2.2e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 AET39649.1 - 4.5e-09 36.0 3.6 5.9e-09 35.6 1.3 2.0 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain DUF2703 PF10865.3 AET39649.1 - 0.074 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) DUF4583 PF15190.1 AET39649.1 - 0.082 12.5 0.3 0.25 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4583) AA_permease_2 PF13520.1 AET39650.1 - 7.5e-54 182.8 63.3 9.4e-54 182.5 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AET39650.1 - 6.8e-14 51.0 52.5 1e-13 50.5 36.4 1.2 1 0 0 1 1 1 1 Amino acid permease Init_tRNA_PT PF04179.7 AET39651.1 - 1.2e-147 492.4 0.1 1.4e-147 492.2 0.1 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Glyco_trans_4_2 PF13477.1 AET39651.1 - 0.06 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Ribosomal_L30 PF00327.15 AET39652.1 - 1.4e-14 53.4 0.1 1.7e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_60s PF00428.14 AET39653.1 - 4.9e-27 94.1 11.5 5.6e-27 93.9 8.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 AET39653.1 - 0.18 9.9 1.9 0.19 9.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4611 PF15387.1 AET39653.1 - 5 7.3 5.7 28 4.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Mito_carr PF00153.22 AET39654.1 - 3.1e-62 206.2 5.3 1.9e-22 78.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 AET39655.1 - 3.6e-50 167.6 5.7 4.2e-17 61.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AIRC PF00731.15 AET39657.1 - 1.7e-64 215.6 1.7 3e-64 214.8 1.2 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 AET39657.1 - 1.1e-60 203.8 0.0 1.9e-60 203.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AET39657.1 - 5.4e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 AET39657.1 - 0.0027 16.8 0.1 0.0053 15.9 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.8 AET39657.1 - 0.012 15.0 0.0 0.13 11.6 0.0 2.2 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 AET39657.1 - 0.034 13.4 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain F420_oxidored PF03807.12 AET39657.1 - 0.059 13.8 0.2 0.26 11.7 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ATPgrasp_Ter PF15632.1 AET39657.1 - 0.075 11.7 0.0 2.5 6.7 0.0 2.5 3 0 0 3 3 3 0 ATP-grasp in the biosynthetic pathway with Ter operon CoA_binding_2 PF13380.1 AET39657.1 - 0.15 12.2 1.1 23 5.2 0.1 3.0 2 1 1 3 3 3 0 CoA binding domain Zn_clus PF00172.13 AET39658.1 - 4.1e-09 36.1 6.2 9.5e-09 35.0 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_21 PF13506.1 AET39659.1 - 3.1e-19 68.9 0.0 3.2e-14 52.5 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 AET39659.1 - 1.2e-11 44.8 0.0 8.8e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AET39659.1 - 8.7e-06 25.5 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Complex1_LYR PF05347.10 AET39660.1 - 4.8e-13 48.6 0.5 5.6e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AET39660.1 - 2.2e-10 40.5 0.6 2.7e-10 40.2 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.22 AET39661.1 - 9.5e-43 145.4 0.2 2.2e-42 144.2 0.2 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 AET39661.1 - 2.6e-12 46.5 26.8 2.3e-06 27.5 6.8 2.6 2 0 0 2 2 2 2 LIM domain DUF506 PF04720.7 AET39661.1 - 0.0073 15.9 3.6 0.018 14.6 2.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF506) ANAPC15 PF15243.1 AET39661.1 - 0.012 15.6 7.2 0.044 13.8 5.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Sigma70_ner PF04546.8 AET39661.1 - 0.2 11.2 7.8 1.5 8.3 5.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 AET39661.1 - 6 6.3 12.3 12 5.4 8.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 AET39661.1 - 9 5.9 11.2 6.5 6.4 4.3 2.5 2 0 0 2 2 2 0 FAM176 family LSM PF01423.17 AET39662.1 - 2.7e-15 55.6 0.0 3.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AET39662.1 - 4.8e-05 23.1 0.0 6.2e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain F1F0-ATPsyn_F PF10791.4 AET39663.1 - 5.7e-40 135.4 0.2 6.4e-40 135.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi NAD_binding_8 PF13450.1 AET39664.1 - 0.00014 21.8 0.0 0.00036 20.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AET39664.1 - 0.00085 19.1 0.0 0.0033 17.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AET39664.1 - 0.0053 16.8 0.0 3.9 7.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AET39664.1 - 0.058 13.2 0.0 0.74 9.6 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AET39664.1 - 0.11 12.6 0.0 11 6.1 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 AET39664.1 - 0.15 11.1 0.0 0.35 9.9 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Lipase_GDSL PF00657.17 AET39665.1 - 1e-22 81.1 0.1 1.2e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 AET39665.1 - 3e-22 79.6 0.0 3.4e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BCS1_N PF08740.6 AET39666.1 - 6.2e-48 162.8 0.2 1.2e-47 162.0 0.1 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 AET39666.1 - 3.6e-20 72.4 0.0 3.4e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AET39666.1 - 2.6e-06 28.2 0.0 7.6e-06 26.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 AET39666.1 - 0.00051 20.1 0.0 0.0033 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AET39666.1 - 0.00094 19.0 0.0 0.0056 16.5 0.0 2.1 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 AET39666.1 - 0.0025 17.6 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AET39666.1 - 0.0029 17.2 0.0 0.042 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AET39666.1 - 0.0031 17.8 0.0 0.0094 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 AET39666.1 - 0.0034 17.3 0.1 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AET39666.1 - 0.0035 16.4 0.0 0.0092 15.0 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AET39666.1 - 0.004 16.8 0.0 0.0085 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AET39666.1 - 0.004 17.1 0.0 0.0078 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 AET39666.1 - 0.0058 16.0 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AET39666.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 AET39666.1 - 0.026 14.0 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 AET39666.1 - 0.031 13.9 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 AET39666.1 - 0.038 14.2 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 AET39666.1 - 0.049 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 AET39666.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AET39666.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 AET39666.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 KaiC ATP_bind_1 PF03029.12 AET39666.1 - 0.061 12.8 0.1 0.82 9.1 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 AET39666.1 - 0.093 12.3 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 1 0 NACHT domain AAA_23 PF13476.1 AET39666.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AET39666.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_11 PF13086.1 AET39666.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 AET39667.1 - 2.6e-42 141.2 20.4 2.5e-09 36.6 0.4 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 AET39667.1 - 0.0085 15.8 5.7 0.29 10.8 0.3 3.5 2 1 2 4 4 4 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 AET39667.1 - 0.066 13.0 0.1 3.3 7.6 0.0 3.0 3 0 0 3 3 3 0 YmzC-like protein PNP_UDP_1 PF01048.15 AET39668.1 - 1.8e-44 151.4 0.0 2.1e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DEAD PF00270.24 AET39669.1 - 1.1e-41 142.1 0.0 1.9e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET39669.1 - 1.2e-25 89.1 0.1 2.4e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 AET39669.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Pkinase PF00069.20 AET39670.1 - 8e-62 208.7 0.0 1.3e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39670.1 - 5.4e-39 133.8 0.0 7.5e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET39670.1 - 0.00034 19.6 0.0 0.00066 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.27 AET39672.1 - 2.2e-14 52.6 1.3 0.0035 17.1 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF290 PF01060.18 AET39672.1 - 0.088 12.8 1.6 1.1 9.2 0.1 2.7 2 1 0 2 2 2 0 Transthyretin-like family zf-HC5HC2H_2 PF13832.1 AET39673.1 - 1e-31 109.1 7.0 1e-31 109.1 4.9 2.8 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 AET39673.1 - 9.2e-28 96.2 4.9 9.2e-28 96.2 3.4 3.2 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 AET39673.1 - 5.5e-14 51.1 3.5 5.5e-14 51.1 2.4 2.6 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.4 AET39673.1 - 1.1e-11 45.2 0.2 2.2e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD PF00628.24 AET39673.1 - 1.2e-10 40.9 19.4 4e-10 39.2 3.0 2.8 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 AET39673.1 - 0.00035 20.2 17.0 0.04 13.6 4.0 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 AET39673.1 - 0.006 16.5 17.7 0.087 12.8 5.9 2.6 2 0 0 2 2 2 2 RING-like domain C1_1 PF00130.17 AET39673.1 - 0.012 15.3 11.5 0.074 12.7 0.2 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 AET39674.1 - 2.5e-64 216.9 0.1 1.4e-63 214.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39674.1 - 1.4e-35 122.5 0.0 3.6e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 AET39674.1 - 1.7e-29 101.3 23.6 2.7e-16 59.0 3.4 3.6 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 AET39674.1 - 5.6e-19 67.6 36.3 3e-10 39.6 10.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 AET39674.1 - 7.4e-12 45.5 0.3 7.4e-12 45.5 0.2 2.4 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 AET39674.1 - 0.002 17.1 0.7 0.011 14.7 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Lgl_C PF08596.5 AET39675.1 - 9e-120 399.7 0.2 2.4e-119 398.3 0.1 1.8 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal LLGL PF08366.8 AET39675.1 - 0.0039 17.0 1.5 0.38 10.6 0.0 3.0 3 0 0 3 3 3 1 LLGL2 WD40 PF00400.27 AET39675.1 - 0.027 14.3 2.5 16 5.5 0.0 5.2 6 0 0 6 6 6 0 WD domain, G-beta repeat Cid2 PF09774.4 AET39676.1 - 5.9e-28 97.8 0.1 7.5e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 IDO PF01231.13 AET39677.1 - 5.6e-148 492.8 0.0 6.5e-148 492.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase tRNA-synt_His PF13393.1 AET39678.1 - 5.9e-39 133.9 0.0 6.9e-38 130.4 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AET39678.1 - 7e-19 68.0 0.0 1.9e-18 66.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AET39678.1 - 4.8e-14 52.0 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 AET39678.1 - 0.0017 17.2 0.0 0.032 13.0 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 AET39678.1 - 0.016 14.3 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) AIM24 PF01987.12 AET39679.1 - 2.7e-09 36.7 0.0 2.2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 NuA4 PF09340.5 AET39680.1 - 2.6e-25 87.8 2.6 3.3e-25 87.5 1.8 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Tho2 PF11262.3 AET39680.1 - 0.062 12.3 1.8 0.063 12.3 1.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4164 PF13747.1 AET39680.1 - 0.16 12.1 2.0 0.26 11.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) G6PD_N PF00479.17 AET39680.1 - 0.17 12.0 2.4 0.2 11.8 1.7 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Rho_Binding PF08912.6 AET39680.1 - 0.26 11.6 7.2 0.41 10.9 5.0 1.4 1 0 0 1 1 1 0 Rho Binding DUF3896 PF13035.1 AET39680.1 - 0.4 10.7 5.7 0.62 10.1 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Vfa1 PF08432.5 AET39680.1 - 0.81 9.6 6.8 0.94 9.4 4.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2811 PF10929.3 AET39680.1 - 1.9 8.5 4.8 18 5.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) UPF0449 PF15136.1 AET39680.1 - 5.5 7.2 6.5 3 8.1 2.9 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Thioredoxin_4 PF13462.1 AET39681.1 - 8.5e-07 29.1 0.0 1.6e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Gln-synt_C PF00120.19 AET39682.1 - 4.5e-63 212.8 0.0 5.4e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AET39682.1 - 6.8e-20 70.4 0.0 1.3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain V-ATPase_H_N PF03224.9 AET39683.1 - 8.5e-66 222.1 11.4 8.5e-66 222.1 7.9 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 AET39683.1 - 9.3e-40 135.2 10.9 1.1e-39 134.9 1.3 3.2 2 1 1 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.1 AET39683.1 - 0.0011 19.1 0.3 1.5 9.1 0.0 3.8 3 2 0 3 3 3 2 HEAT repeats HEAT PF02985.17 AET39683.1 - 0.046 13.8 0.7 5.8 7.2 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.18 AET39683.1 - 0.085 12.7 1.3 1.7 8.5 0.3 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat YlqD PF11068.3 AET39684.1 - 1.5 8.8 7.8 0.66 10.0 0.1 2.8 3 1 0 3 3 3 0 YlqD protein PCI PF01399.22 AET39685.1 - 1.9e-06 28.0 0.0 4.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain ABC2_membrane_6 PF06182.6 AET39685.1 - 0.0057 16.2 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein Tmemb_14 PF03647.8 AET39687.1 - 1.9e-24 85.8 4.8 2.1e-24 85.7 3.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 AET39687.1 - 0.018 15.3 0.8 0.022 15.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) DUF4131 PF13567.1 AET39687.1 - 0.045 13.1 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Gram_pos_anchor PF00746.16 AET39687.1 - 3 7.7 0.0 3 7.7 0.0 3.2 4 0 0 4 4 4 0 Gram positive anchor G-gamma PF00631.17 AET39688.1 - 1.5e-26 91.9 0.0 1.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain Evr1_Alr PF04777.8 AET39689.1 - 5.5e-26 90.3 0.3 9.1e-26 89.6 0.2 1.3 1 0 0 1 1 1 1 Erv1 / Alr family TIP41 PF04176.8 AET39690.1 - 1.1e-72 243.1 3.1 1.5e-72 242.6 1.8 1.5 2 0 0 2 2 2 1 TIP41-like family Rpr2 PF04032.11 AET39690.1 - 0.044 13.6 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TPR_2 PF07719.12 AET39691.1 - 2.9e-06 26.7 2.4 0.00017 21.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 AET39691.1 - 2.2e-05 24.0 1.3 0.00074 19.1 0.6 2.5 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 AET39691.1 - 0.00027 21.5 0.1 0.004 17.7 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AET39691.1 - 0.0018 17.7 0.1 0.18 11.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AET39691.1 - 0.0035 17.8 0.1 1.2 9.9 0.0 3.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AET39691.1 - 0.012 15.9 0.1 9.5 6.9 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AET39691.1 - 0.022 14.5 2.9 0.31 10.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 AET39691.1 - 0.023 14.8 0.4 30 5.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 AET39691.1 - 0.031 14.6 0.0 4.4 7.7 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 AET39691.1 - 0.049 13.4 0.3 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3890 PF13029.1 AET39691.1 - 2.3 8.3 7.4 3.3 7.8 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3890) eIF-5_eIF-2B PF01873.12 AET39692.1 - 3.3e-41 139.8 0.0 5.7e-41 139.0 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 AET39692.1 - 3.6e-25 87.7 0.0 6.7e-24 83.6 0.0 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF573 PF04504.9 AET39693.1 - 0.031 14.5 0.5 0.15 12.3 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function, DUF573 F-box-like PF12937.2 AET39694.1 - 5.8e-05 22.7 0.1 0.00013 21.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AET39694.1 - 0.061 13.0 0.5 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 F-box domain Nucleoporin_C PF03177.9 AET39695.1 - 9.5e-139 463.5 11.3 1.5e-138 462.9 7.8 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 AET39695.1 - 1e-112 377.0 12.0 1.8e-112 376.1 8.3 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Atg8 PF02991.11 AET39696.1 - 8.5e-48 160.6 0.1 9.6e-48 160.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 AET39696.1 - 1.1e-07 31.9 0.0 1.4e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Nsp1_C PF05064.8 AET39697.1 - 0.89 9.2 5.9 1.8 8.2 0.4 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region tRNA-synt_1 PF00133.17 AET39698.1 - 2.6e-231 768.8 0.1 2e-230 765.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AET39698.1 - 3.4e-27 95.0 0.9 1.1e-26 93.4 0.2 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AET39698.1 - 4.3e-18 65.1 3.2 3e-06 26.1 0.4 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 AET39698.1 - 0.00018 20.7 0.0 0.002 17.3 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain HSP70 PF00012.15 AET39699.1 - 7e-270 896.1 8.9 7.9e-270 895.9 6.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AET39699.1 - 2.2e-17 62.6 0.0 2.7e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AET39699.1 - 0.00027 20.5 0.0 0.00065 19.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 AET39699.1 - 0.029 13.1 2.0 0.32 9.7 0.1 2.5 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 AET39699.1 - 0.35 9.9 3.1 0.42 9.6 0.0 2.5 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase AAR2 PF05282.6 AET39700.1 - 1.2e-55 188.9 0.0 1.5e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S8e PF01201.17 AET39701.1 - 2.4e-51 173.3 1.8 2.8e-51 173.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e AdoMetDC_leader PF08132.6 AET39701.1 - 0.089 12.7 0.5 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 S-adenosyl-l-methionine decarboxylase leader peptide zf-CSL PF05207.8 AET39702.1 - 4.4e-24 83.7 1.5 5.7e-24 83.3 1.1 1.2 1 0 0 1 1 1 1 CSL zinc finger TF_Zn_Ribbon PF08271.7 AET39702.1 - 0.049 12.9 2.6 0.052 12.8 0.5 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding ATPase-cat_bd PF12156.3 AET39702.1 - 0.082 13.4 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase ADH_zinc_N_2 PF13602.1 AET39703.1 - 1.1e-10 42.4 0.0 2.1e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AET39703.1 - 2.7e-07 30.3 0.1 4.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain UQ_con PF00179.21 AET39704.1 - 5.5e-28 97.1 0.5 8.7e-28 96.5 0.1 1.5 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AET39704.1 - 0.00068 19.3 0.0 0.002 17.8 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 AET39704.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 1.9 2 1 0 2 2 2 1 RWD domain YjgP_YjgQ PF03739.9 AET39704.1 - 0.13 10.9 0.6 0.18 10.4 0.4 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Pribosyltran_N PF13793.1 AET39705.1 - 1.5e-44 150.3 0.4 6.8e-42 141.8 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AET39705.1 - 7.8e-35 120.2 1.9 1.7e-29 102.9 0.9 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AET39705.1 - 2e-12 46.9 0.8 3.8e-11 42.7 0.3 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AET39705.1 - 0.016 14.4 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase UCH PF00443.24 AET39706.1 - 1.1e-69 234.5 1.8 3.9e-69 232.7 1.3 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AET39706.1 - 1.3e-26 93.6 10.8 5.4e-22 78.5 1.2 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PTB PF08416.8 AET39706.1 - 0.042 13.7 0.0 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Phosphotyrosine-binding domain Fungal_trans PF04082.13 AET39707.1 - 1.1e-23 83.4 4.0 2.4e-23 82.3 2.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET39707.1 - 4.1e-08 32.9 10.6 6.8e-08 32.3 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.16 AET39708.1 - 9.9e-33 112.4 0.0 1.3e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 AET39708.1 - 2.4e-15 55.8 0.2 4.3e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 AET39708.1 - 3.4e-10 39.6 0.0 5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Kinesin PF00225.18 AET39709.1 - 5.9e-108 360.5 3.0 5.9e-108 360.5 2.1 2.8 3 0 0 3 3 3 2 Kinesin motor domain NPV_P10 PF05531.7 AET39709.1 - 1.1 9.6 13.9 7.8 6.8 2.2 5.8 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Sel1 PF08238.7 AET39710.1 - 1.9e-43 145.9 11.6 4.2e-08 33.5 0.6 7.5 7 0 0 7 7 7 7 Sel1 repeat Rad51 PF08423.6 AET39711.1 - 1.6e-137 456.5 0.0 2.1e-137 456.1 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AET39711.1 - 9.7e-14 51.2 0.0 1.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 AET39711.1 - 1.9e-12 47.1 0.0 5.2e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 AET39711.1 - 1.3e-10 40.9 0.0 1.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AET39711.1 - 1.4e-05 24.3 0.0 2.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 AET39711.1 - 0.0099 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 AET39711.1 - 0.021 13.6 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HHH PF00633.18 AET39711.1 - 0.023 14.4 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sec7 PF01369.15 AET39712.1 - 3.2e-24 85.6 1.4 3.2e-24 85.6 1.0 1.8 2 0 0 2 2 2 1 Sec7 domain AnfO_nitrog PF09582.5 AET39712.1 - 0.051 12.7 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Proteasome PF00227.21 AET39713.1 - 2.4e-36 124.8 0.0 2.7e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cmc1 PF08583.5 AET39714.1 - 2.1e-18 65.8 8.0 2.1e-18 65.8 5.5 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 AET39714.1 - 0.021 14.2 4.0 0.033 13.5 2.8 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF1088 PF06469.6 AET39714.1 - 0.098 12.0 2.5 0.11 11.9 1.5 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1088) CBM_14 PF01607.19 AET39714.1 - 0.14 12.0 1.3 0.2 11.6 0.9 1.3 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain CHCH PF06747.8 AET39714.1 - 0.61 10.0 4.1 11 6.1 0.2 2.4 2 0 0 2 2 2 0 CHCH domain RICTOR_N PF14664.1 AET39715.1 - 4.2e-101 338.2 13.8 4.2e-101 338.2 9.6 2.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 AET39715.1 - 6.3e-76 254.3 0.4 6.3e-76 254.3 0.3 4.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 AET39715.1 - 1.1e-27 95.7 0.8 1.5e-26 92.1 0.0 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 AET39715.1 - 7.2e-21 74.2 3.4 2e-20 72.8 0.1 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_2 PF13646.1 AET39715.1 - 1.8e-05 24.8 0.0 0.62 10.3 0.0 4.8 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 AET39715.1 - 5.1e-05 23.0 0.0 1.9 8.7 0.0 4.5 5 0 0 5 5 5 2 HEAT repeat MAP65_ASE1 PF03999.7 AET39716.1 - 0.005 15.5 5.7 0.0057 15.3 3.9 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) PEPcase PF00311.12 AET39716.1 - 0.02 12.7 1.2 0.021 12.7 0.9 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase RE_HaeIII PF09556.5 AET39716.1 - 0.046 12.5 0.5 0.049 12.5 0.3 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease HORMA PF02301.13 AET39716.1 - 0.077 12.4 0.5 0.083 12.3 0.4 1.2 1 0 0 1 1 1 0 HORMA domain DUF1355 PF07090.6 AET39716.1 - 0.077 12.3 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1355) DUF4570 PF15134.1 AET39716.1 - 2.2 8.1 5.8 9.2 6.1 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) Meth_synt_2 PF01717.13 AET39717.1 - 1.6e-142 474.2 0.0 4.4e-134 446.5 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 AET39717.1 - 3.6e-128 427.2 0.0 2.1e-115 385.2 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SEP PF08059.8 AET39718.1 - 2e-24 85.6 0.2 2e-24 85.6 0.1 2.2 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 AET39718.1 - 2.1e-13 50.1 0.0 4.1e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 AET39718.1 - 7.7e-12 44.5 0.6 1.7e-11 43.4 0.4 1.6 1 0 0 1 1 1 1 UBA-like domain PTH2 PF01981.11 AET39719.1 - 1.2e-44 150.6 0.0 1.7e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Chorismate_bind PF00425.13 AET39720.1 - 1.2e-89 300.0 0.0 1.7e-89 299.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 AET39720.1 - 3.6e-24 85.3 0.0 3.1e-23 82.3 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region PP2C PF00481.16 AET39721.1 - 2.6e-77 259.6 0.1 3.5e-77 259.2 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3873 PF12989.2 AET39721.1 - 0.012 15.7 0.7 0.037 14.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) TatD_DNase PF01026.16 AET39722.1 - 3.3e-37 128.0 0.0 1.1e-36 126.3 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Myb_DNA-bind_6 PF13921.1 AET39723.1 - 3.5e-12 46.2 1.6 6.4e-10 38.9 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AET39723.1 - 1.1e-07 31.7 0.8 5e-06 26.4 0.2 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain MOZ_SAS PF01853.13 AET39724.1 - 4.7e-76 254.2 0.9 4.7e-76 254.2 0.6 1.5 2 0 0 2 2 2 1 MOZ/SAS family Pepsin-I3 PF06394.8 AET39724.1 - 0.021 14.4 0.7 0.05 13.2 0.5 1.6 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Acetyltransf_1 PF00583.19 AET39724.1 - 0.067 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RRM_6 PF14259.1 AET39725.1 - 1.2e-07 31.6 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET39725.1 - 3.2e-06 26.6 0.1 7.8e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET39725.1 - 2.8e-05 23.8 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelP_N PF04592.9 AET39725.1 - 0.06 12.7 13.0 0.15 11.3 9.0 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Sec61_beta PF03911.11 AET39726.1 - 5.1e-18 64.5 0.5 6.4e-18 64.2 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family Cas_Csx9 PF09658.5 AET39726.1 - 0.042 12.6 0.0 0.045 12.5 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) DUF2897 PF11446.3 AET39726.1 - 0.45 10.3 3.5 0.66 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) tRNA-synt_2b PF00587.20 AET39727.1 - 2.8e-29 101.9 0.0 4.7e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AET39727.1 - 0.0032 17.3 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain PALP PF00291.20 AET39728.1 - 9.7e-71 238.4 0.3 1.2e-70 238.1 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 AET39728.1 - 9.7e-37 124.4 0.1 3.5e-24 84.2 0.0 2.5 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase MMR1 PF08505.5 AET39729.1 - 1.9e-15 57.5 11.4 1.9e-15 57.5 7.9 2.8 2 1 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein IncA PF04156.9 AET39729.1 - 5.9 6.4 8.8 0.59 9.7 3.1 1.6 2 0 0 2 2 2 0 IncA protein Peroxin-13_N PF04088.8 AET39730.1 - 1.8e-55 187.1 0.9 2.7e-55 186.6 0.6 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 AET39730.1 - 7.5e-11 41.2 0.1 1.7e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 AET39730.1 - 3.7e-09 36.0 0.0 6.2e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AET39730.1 - 1.5e-08 33.9 0.0 3.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 AET39730.1 - 0.00024 21.1 0.1 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain eIF3_subunit PF08597.5 AET39731.1 - 4.7e-55 186.8 22.7 4.4e-53 180.3 15.7 2.0 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3602 PF12223.3 AET39732.1 - 6e-21 74.6 13.5 4.9e-14 52.4 0.1 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Glu_synthase PF01645.12 AET39733.1 - 9.9e-156 518.2 0.0 5.3e-155 515.8 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 AET39733.1 - 2.7e-136 454.0 0.0 5.2e-136 453.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 AET39733.1 - 6.2e-117 389.9 0.0 6.4e-116 386.6 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 AET39733.1 - 3.1e-57 192.8 0.6 6.6e-57 191.7 0.4 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 AET39733.1 - 8.5e-24 83.3 0.0 1.7e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 AET39733.1 - 8.1e-13 48.7 0.0 2.8e-12 46.9 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AET39733.1 - 3.9e-09 36.7 0.3 4.2e-07 30.2 0.0 3.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AET39733.1 - 4.7e-09 36.1 0.0 1.4e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AET39733.1 - 2.7e-07 30.8 0.1 0.0055 16.7 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AET39733.1 - 2.6e-06 26.6 0.5 1.8e-05 23.8 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 AET39733.1 - 1.3e-05 24.4 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 AET39733.1 - 2.4e-05 23.0 1.3 3.2e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 AET39733.1 - 0.00014 20.8 0.0 0.00027 19.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 AET39733.1 - 0.00032 19.8 0.0 0.0011 18.0 0.0 1.9 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 AET39733.1 - 0.00038 19.6 0.0 0.00082 18.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AET39733.1 - 0.0012 18.0 0.0 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 AET39733.1 - 0.0051 15.7 0.3 0.037 12.8 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 AET39733.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.1 AET39733.1 - 0.019 14.9 0.0 0.063 13.2 0.0 1.8 2 0 0 2 2 1 0 Glutamine amidotransferase domain NAD_binding_9 PF13454.1 AET39733.1 - 0.022 14.5 0.2 0.12 12.1 0.0 2.4 3 0 0 3 3 2 0 FAD-NAD(P)-binding FMN_dh PF01070.13 AET39733.1 - 0.057 12.2 0.5 0.33 9.7 0.5 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_binding_7 PF13241.1 AET39733.1 - 0.17 12.1 1.6 7.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 AET39733.1 - 0.26 10.1 0.1 0.42 9.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AdoHcyase_NAD PF00670.16 AET39733.1 - 0.42 10.4 5.3 8.2 6.2 0.5 3.3 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PRELI PF04707.9 AET39734.1 - 6.4e-45 152.5 0.1 7.4e-45 152.3 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family NMT PF01233.14 AET39736.1 - 2.2e-81 271.2 0.0 4.1e-81 270.3 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 AET39736.1 - 6.2e-77 257.2 0.7 8.9e-77 256.7 0.2 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 AET39736.1 - 1.7e-05 24.6 0.0 0.00014 21.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AET39736.1 - 0.00049 20.2 0.0 0.07 13.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AET39736.1 - 0.0024 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AET39736.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family WD40 PF00400.27 AET39737.1 - 1.1e-13 50.4 8.7 2.7e-05 23.8 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.1 AET39737.1 - 0.13 12.6 0.3 1 9.7 0.0 2.8 3 1 0 3 3 3 0 PQQ-like domain DUF1064 PF06356.6 AET39738.1 - 4.9e-05 23.3 0.0 0.0058 16.6 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1064) Nop PF01798.13 AET39739.1 - 3.5e-60 201.6 0.1 8.3e-60 200.4 0.1 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AET39739.1 - 6.6e-27 93.0 0.1 1.7e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AET39739.1 - 4.7e-23 81.1 0.1 4.7e-23 81.1 0.1 2.9 2 1 0 2 2 2 1 NOP5NT (NUC127) domain MIP-T3 PF10243.4 AET39739.1 - 0.51 8.7 39.2 0.72 8.2 27.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDHD PF02862.12 AET39739.1 - 0.61 9.8 10.0 1 9.1 6.9 1.5 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 AET39739.1 - 0.64 9.9 20.1 0.93 9.3 13.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family POC1 PF10450.4 AET39740.1 - 9.8e-38 129.4 0.3 1.1e-37 129.3 0.2 1.0 1 0 0 1 1 1 1 POC1 chaperone Prefoldin_2 PF01920.15 AET39741.1 - 4.2e-24 84.3 14.1 5.1e-24 84.0 9.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF1192 PF06698.6 AET39741.1 - 0.00037 20.2 2.1 0.037 13.8 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1192) FTA4 PF13093.1 AET39741.1 - 0.02 14.3 4.3 0.029 13.8 3.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prefoldin PF02996.12 AET39741.1 - 0.025 14.2 8.7 0.14 11.8 0.4 2.2 1 1 1 2 2 2 0 Prefoldin subunit YgaB PF14182.1 AET39741.1 - 0.055 13.7 0.7 0.055 13.7 0.5 2.2 2 0 0 2 2 2 0 YgaB-like protein Guanylin PF02058.10 AET39741.1 - 0.059 13.4 0.5 0.11 12.6 0.3 1.5 1 1 0 1 1 1 0 Guanylin precursor HrpB7 PF09486.5 AET39741.1 - 0.095 12.6 3.5 0.18 11.6 0.3 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1732 PF08340.6 AET39741.1 - 0.097 12.5 2.5 0.2 11.4 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) CENP-F_leu_zip PF10473.4 AET39741.1 - 0.18 11.6 12.4 0.52 10.1 2.9 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Stk19 PF10494.4 AET39741.1 - 0.18 11.1 2.4 0.19 11.0 1.6 1.3 1 1 0 1 1 1 0 Serine-threonine protein kinase 19 Bcr-Abl_Oligo PF09036.5 AET39741.1 - 0.19 11.6 0.8 0.31 11.0 0.6 1.6 1 1 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain GED PF02212.13 AET39741.1 - 0.29 11.0 3.9 0.22 11.4 1.0 1.9 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF641 PF04859.7 AET39741.1 - 0.39 10.4 6.8 0.92 9.2 0.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin_3 PF13758.1 AET39741.1 - 0.51 10.1 4.8 4.6 7.0 3.3 2.5 1 1 0 1 1 1 0 Prefoldin subunit Spc24 PF08286.6 AET39741.1 - 0.57 9.8 11.2 1.2 8.8 3.0 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.7 AET39741.1 - 0.6 9.9 3.7 2.7 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4164 PF13747.1 AET39741.1 - 0.62 10.2 7.1 2.2 8.4 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) FliJ PF02050.11 AET39741.1 - 1.1 9.3 13.7 0.81 9.7 0.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein BLOC1_2 PF10046.4 AET39741.1 - 1.2 9.3 8.7 0.77 9.9 1.8 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.8 AET39741.1 - 1.4 8.4 4.6 1.8 8.0 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.2 AET39741.1 - 1.5 8.6 11.8 7 6.4 8.2 1.9 1 1 0 1 1 1 0 Tropomyosin like DivIVA PF05103.8 AET39741.1 - 2.4 8.2 11.1 3.7 7.5 3.2 2.1 2 0 0 2 2 2 0 DivIVA protein Ly49 PF08391.5 AET39741.1 - 4.4 7.4 7.0 6.2 6.9 0.4 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region IncA PF04156.9 AET39741.1 - 4.6 6.8 15.2 16 5.0 10.5 1.7 1 1 0 1 1 1 0 IncA protein DUF3166 PF11365.3 AET39741.1 - 4.8 7.7 10.3 6.1 7.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) ADIP PF11559.3 AET39741.1 - 4.8 7.0 12.0 7 6.5 2.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2175 PF09943.4 AET39741.1 - 9.2 6.3 6.6 20 5.3 1.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) COQ9 PF08511.6 AET39742.1 - 2.6e-19 68.5 0.3 5.7e-19 67.4 0.1 1.6 2 0 0 2 2 2 1 COQ9 ADH_N PF08240.7 AET39743.1 - 8.6e-26 89.8 2.7 8.6e-26 89.8 1.8 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AET39743.1 - 1e-18 67.1 0.1 1.7e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 AET39743.1 - 0.014 14.8 0.2 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 AET39743.1 - 0.023 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 AET39743.1 - 0.034 13.2 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 AET39743.1 - 0.046 13.7 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 AET39743.1 - 0.063 12.8 1.9 0.1 12.1 1.3 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 AET39743.1 - 0.1 12.8 0.1 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding HycI PF01750.13 AET39743.1 - 0.11 11.9 0.2 0.26 10.8 0.2 1.5 1 0 0 1 1 1 0 Hydrogenase maturation protease AAA_18 PF13238.1 AET39744.1 - 2e-29 102.5 0.2 2e-29 102.5 0.2 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AET39744.1 - 3.1e-15 57.0 0.5 6e-15 56.1 0.3 1.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AET39744.1 - 8.4e-05 22.5 0.0 0.00024 21.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AET39744.1 - 0.00011 22.0 0.0 0.065 13.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AET39744.1 - 0.00082 19.5 0.0 0.002 18.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 AET39744.1 - 0.00083 19.5 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 AET39744.1 - 0.00083 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AET39744.1 - 0.001 19.2 0.0 0.0028 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AET39744.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.12 AET39744.1 - 0.0022 17.3 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_19 PF13245.1 AET39744.1 - 0.0024 17.6 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain Cytidylate_kin2 PF13189.1 AET39744.1 - 0.0027 17.6 0.1 0.05 13.5 0.1 2.4 1 1 0 1 1 1 1 Cytidylate kinase-like family Zeta_toxin PF06414.7 AET39744.1 - 0.0027 16.8 0.0 0.0061 15.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 AET39744.1 - 0.0029 16.8 0.0 0.0081 15.3 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 AET39744.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 NTPase ADK PF00406.17 AET39744.1 - 0.0084 15.9 0.1 0.84 9.5 0.0 2.3 2 0 0 2 2 2 1 Adenylate kinase Viral_helicase1 PF01443.13 AET39744.1 - 0.014 14.8 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 AET39744.1 - 0.021 13.7 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 AET39744.1 - 0.023 14.4 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GvpD PF07088.6 AET39744.1 - 0.046 12.0 0.1 0.073 11.3 0.0 1.4 2 0 0 2 2 2 0 GvpD gas vesicle protein MobB PF03205.9 AET39744.1 - 0.088 12.5 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NOT2_3_5 PF04153.13 AET39745.1 - 1.5e-34 118.8 0.4 1.9e-34 118.4 0.3 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family zf-Mss51 PF13824.1 AET39746.1 - 3.9e-19 68.2 0.8 1.3e-18 66.5 0.3 2.0 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1713 PF08213.6 AET39747.1 - 1e-13 50.5 24.4 1.6e-13 49.9 16.9 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Heme_oxygenase PF01126.15 AET39748.1 - 1.9e-13 50.4 0.1 5.4e-13 48.9 0.1 1.8 1 1 0 1 1 1 1 Heme oxygenase ENTH PF01417.15 AET39749.1 - 1.5e-43 147.6 0.0 3.1e-43 146.6 0.0 1.6 1 0 0 1 1 1 1 ENTH domain PAT1 PF09770.4 AET39749.1 - 0.013 13.7 50.1 0.018 13.3 34.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 AET39749.1 - 0.056 11.6 60.8 0.077 11.1 42.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal tRNA-synt_1g PF09334.6 AET39750.1 - 2.1e-105 352.6 0.0 2.6e-105 352.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AET39750.1 - 1.8e-26 92.3 0.0 7.4e-11 40.7 0.0 3.8 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 AET39750.1 - 9.9e-09 34.7 0.0 4.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 AET39750.1 - 0.0014 18.4 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 AET39750.1 - 0.0052 15.5 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) Hira PF07569.6 AET39750.1 - 0.072 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split DNA_pol_E_B PF04042.11 AET39751.1 - 1.4e-41 142.0 0.0 1.9e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B BTV_NS2 PF04514.7 AET39752.1 - 1.2 7.9 9.5 1.4 7.7 6.6 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PDDEXK_1 PF12705.2 AET39752.1 - 1.9 7.8 5.7 2 7.7 4.0 1.0 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily HSP20 PF00011.16 AET39754.1 - 9.4e-19 67.1 0.0 1.2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Peptidase_M1 PF01433.15 AET39755.1 - 6.4e-145 483.1 0.7 9.6e-145 482.5 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AET39755.1 - 5.2e-84 282.2 2.2 1.1e-83 281.1 0.7 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AET39755.1 - 2e-20 73.1 0.2 4.8e-20 71.9 0.1 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily RNase_H2-Ydr279 PF09468.5 AET39757.1 - 1.8e-56 191.5 0.9 2.3e-56 191.2 0.6 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) RNase_PH PF01138.16 AET39758.1 - 2.6e-19 69.8 0.0 6.1e-19 68.6 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AET39758.1 - 9.8e-13 47.8 0.0 2.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TIG PF01833.19 AET39758.1 - 0.0024 17.8 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 IPT/TIG domain HAD_2 PF13419.1 AET39759.1 - 3.1e-14 53.5 0.0 1.1e-13 51.8 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AET39759.1 - 2.5e-09 37.8 0.0 3.3e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma70_ner PF04546.8 AET39759.1 - 1.6 8.3 14.7 3.9 7.0 10.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.6 AET39759.1 - 5.9 4.8 11.9 7.6 4.5 8.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.7 AET39759.1 - 9.2 5.4 17.4 13 4.8 12.1 1.2 1 0 0 1 1 1 0 NOA36 protein DUF155 PF02582.9 AET39760.1 - 3.6e-46 157.2 0.4 5.2e-46 156.7 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RCC1_2 PF13540.1 AET39760.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat FAD_binding_1 PF00667.15 AET39761.1 - 1.1e-68 230.9 0.0 1.7e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AET39761.1 - 2e-30 105.6 0.6 3.6e-30 104.8 0.2 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 AET39761.1 - 2.1e-22 79.7 0.0 1.2e-21 77.3 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.5 AET39761.1 - 0.0026 16.5 0.0 0.0052 15.5 0.0 1.4 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) Flavodoxin_5 PF12724.2 AET39761.1 - 0.0073 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Peptidase_C23 PF05379.6 AET39761.1 - 0.066 13.1 0.1 1.7 8.6 0.0 2.8 3 0 0 3 3 3 0 Carlavirus endopeptidase MAGE PF01454.14 AET39762.1 - 2.2e-33 115.2 0.1 2.6e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 MAGE family Metallophos PF00149.23 AET39763.1 - 1.4e-09 37.5 6.8 3.5e-08 33.0 4.7 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AET39763.1 - 7.7e-05 22.5 0.0 0.00088 19.1 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain L_biotic_typeA PF04604.8 AET39766.1 - 0.014 15.0 0.1 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 Type-A lantibiotic LRR_4 PF12799.2 AET39766.1 - 0.14 11.8 13.8 3 7.5 0.1 5.7 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF2201_N PF13203.1 AET39766.1 - 9.9 5.2 8.1 17 4.4 5.6 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Atg31 PF09795.4 AET39767.1 - 8.7e-29 100.2 7.4 5.6e-28 97.6 5.2 1.8 1 1 0 1 1 1 1 Autophagy-related protein 31 TGT PF01702.13 AET39767.1 - 0.035 13.3 0.2 0.06 12.6 0.1 1.3 1 1 0 1 1 1 0 Queuine tRNA-ribosyltransferase DEAD PF00270.24 AET39768.1 - 2.9e-42 144.0 3.9 5.7e-42 143.0 2.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET39768.1 - 5e-26 90.3 0.1 1.4e-25 88.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AET39768.1 - 2.9e-05 24.2 0.1 9.1e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AET39768.1 - 0.00021 20.9 0.2 0.00056 19.6 0.1 1.7 1 1 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AET39768.1 - 0.0047 16.5 0.3 0.012 15.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 AET39768.1 - 0.0058 16.4 0.3 0.014 15.2 0.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 AET39768.1 - 0.0062 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Helicase SNF2_N PF00176.18 AET39768.1 - 0.015 14.1 0.6 0.033 13.0 0.1 1.6 1 1 1 2 2 2 0 SNF2 family N-terminal domain PhoH PF02562.11 AET39768.1 - 0.33 10.1 3.2 0.81 8.8 2.2 1.8 1 1 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.16 AET39768.1 - 0.38 9.9 2.4 0.62 9.3 1.7 1.7 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain PRK PF00485.13 AET39769.1 - 6.3e-14 51.9 0.0 9.1e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Cpn60_TCP1 PF00118.19 AET39770.1 - 2.6e-09 36.2 0.0 5.7e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family AA_permease PF00324.16 AET39771.1 - 5.8e-102 341.4 41.1 7.1e-102 341.2 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET39771.1 - 2.5e-34 118.5 40.8 3.1e-34 118.2 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease Bac_surface_Ag PF01103.18 AET39772.1 - 1.8e-24 86.8 4.5 2.6e-24 86.2 3.1 1.1 1 0 0 1 1 1 1 Surface antigen FHA PF00498.21 AET39773.1 - 4.4e-05 23.5 0.4 0.00042 20.3 0.0 2.5 2 0 0 2 2 2 1 FHA domain BRCT PF00533.21 AET39773.1 - 0.00042 20.4 0.1 0.11 12.7 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Kei1 PF08552.6 AET39774.1 - 1.8e-48 164.6 2.1 2.3e-48 164.3 1.4 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4077 PF13295.1 AET39774.1 - 0.6 9.8 5.7 0.15 11.7 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4077) RIO1 PF01163.17 AET39775.1 - 6.1e-69 231.1 2.6 6.1e-69 231.1 1.8 2.2 2 0 0 2 2 2 1 RIO1 family Peptidase_M15_4 PF13539.1 AET39775.1 - 0.061 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase CDC45 PF02724.9 AET39775.1 - 1.8 6.4 20.5 3.1 5.7 14.2 1.3 1 0 0 1 1 1 0 CDC45-like protein TLD PF07534.11 AET39776.1 - 9.1e-29 100.2 0.3 3.7e-27 94.9 0.1 2.5 1 1 1 2 2 2 2 TLD DUF2361 PF10153.4 AET39777.1 - 4.6e-35 120.2 11.5 4.6e-35 120.2 7.9 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Sec63 PF02889.11 AET39778.1 - 1.2e-133 445.2 0.9 1.6e-90 303.5 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AET39778.1 - 2.5e-53 180.0 1.1 4.6e-28 97.8 0.4 4.3 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 AET39778.1 - 5.1e-20 72.0 0.0 1.9e-09 37.6 0.1 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AET39778.1 - 5.2e-18 64.6 0.0 7.5e-08 32.1 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 AET39778.1 - 4e-07 29.1 0.1 0.00057 18.7 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_22 PF13401.1 AET39778.1 - 1.5e-05 25.1 0.8 0.093 12.8 0.1 4.1 3 2 0 3 3 3 2 AAA domain PhoH PF02562.11 AET39778.1 - 4.1e-05 22.9 0.0 0.022 14.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 AET39778.1 - 6.5e-05 22.6 0.0 0.16 11.7 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 AET39778.1 - 0.00021 20.7 0.1 3.5 7.0 0.0 4.4 4 0 0 4 4 4 2 IstB-like ATP binding protein T2SE PF00437.15 AET39778.1 - 0.0012 17.7 0.0 1.8 7.4 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 AET39778.1 - 0.045 14.0 0.0 0.65 10.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AET39778.1 - 0.052 12.9 2.0 19 4.5 0.0 4.2 3 2 1 5 5 5 0 AAA-like domain Zeta_toxin PF06414.7 AET39778.1 - 0.1 11.6 0.0 7.1 5.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Dynamitin PF04912.9 AET39779.1 - 1.5e-20 73.4 28.8 1.7e-18 66.6 6.5 2.8 1 1 0 2 2 2 2 Dynamitin SlyX PF04102.7 AET39779.1 - 0.021 15.2 2.7 0.021 15.2 1.9 4.0 4 0 0 4 4 3 0 SlyX DHC PF09626.5 AET39779.1 - 0.11 13.1 8.1 0.8 10.3 0.0 2.9 2 1 1 3 3 3 0 Dihaem cytochrome c Baculo_PEP_C PF04513.7 AET39779.1 - 0.11 12.2 5.2 0.25 11.1 0.2 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus U1snRNP70_N PF12220.3 AET39779.1 - 0.41 11.0 9.5 0.46 10.8 0.1 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Occludin_ELL PF07303.8 AET39779.1 - 0.48 11.1 17.9 0.058 14.1 2.6 3.7 2 1 0 3 3 3 0 Occludin homology domain WXG100 PF06013.7 AET39779.1 - 0.81 9.7 6.0 0.94 9.5 0.6 3.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG IncA PF04156.9 AET39779.1 - 1.1 8.7 23.7 0.15 11.6 4.5 3.3 2 1 1 3 3 3 0 IncA protein Laminin_II PF06009.7 AET39779.1 - 1.2 8.8 15.5 0.26 11.0 1.5 3.8 3 1 0 3 3 3 0 Laminin Domain II DUF745 PF05335.8 AET39779.1 - 1.7 8.1 5.1 2 7.9 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF745) DUF3829 PF12889.2 AET39779.1 - 5.2 6.1 14.6 0.62 9.2 4.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Nsp1_C PF05064.8 AET39779.1 - 5.4 6.6 15.6 0.067 12.8 2.7 3.1 3 0 0 3 3 3 0 Nsp1-like C-terminal region Phage_GPO PF05929.6 AET39779.1 - 5.6 6.1 9.9 5.9 6.0 1.5 2.5 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF948 PF06103.6 AET39779.1 - 5.9 6.8 9.7 4.9 7.0 0.0 4.0 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.7 AET39779.1 - 6.1 6.6 23.0 0.18 11.5 6.9 3.4 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Noelin-1 PF12308.3 AET39779.1 - 8.3 6.2 15.4 0.12 12.1 2.4 3.4 3 1 1 5 5 4 0 Neurogenesis glycoprotein Amidase PF01425.16 AET39780.1 - 1.8e-115 386.3 0.0 2.2e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 Amidase SP2 PF03014.9 AET39780.1 - 0.017 13.0 0.3 0.061 11.2 0.1 1.7 2 0 0 2 2 2 0 Structural protein 2 DUF268 PF03269.9 AET39780.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 E2 PF08199.6 AET39780.1 - 0.12 12.0 0.9 0.29 10.7 0.6 1.7 1 0 0 1 1 1 0 Bacteriophage E2-like protein AAA PF00004.24 AET39781.1 - 3.2e-48 163.2 0.0 6.6e-42 142.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 AET39781.1 - 4.7e-08 33.1 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 AET39781.1 - 1.2e-05 24.8 0.0 9.5e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 AET39781.1 - 1.7e-05 24.7 0.0 6e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AET39781.1 - 0.00011 21.9 0.1 0.00089 18.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AET39781.1 - 0.00022 21.2 1.8 0.00053 20.0 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 AET39781.1 - 0.00054 20.1 0.3 0.022 14.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain Bromodomain PF00439.20 AET39781.1 - 0.00059 19.7 0.1 0.0022 17.8 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_19 PF13245.1 AET39781.1 - 0.0022 17.6 0.1 0.053 13.2 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activat PF00158.21 AET39781.1 - 0.0035 16.8 0.0 1.3 8.5 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.11 AET39781.1 - 0.0048 16.1 0.0 0.038 13.2 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 AET39781.1 - 0.0064 15.9 0.0 0.019 14.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AET39781.1 - 0.0073 16.5 0.3 0.12 12.6 0.0 3.2 4 0 0 4 4 4 1 ABC transporter TIP49 PF06068.8 AET39781.1 - 0.0081 14.9 0.0 0.016 13.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 AET39781.1 - 0.016 15.1 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 AET39781.1 - 0.024 14.4 2.1 0.056 13.2 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 AET39781.1 - 0.032 13.3 0.1 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AET39781.1 - 0.046 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 AET39781.1 - 0.049 14.4 0.0 0.049 14.4 0.0 4.2 4 0 0 4 4 3 0 AAA domain AAA_3 PF07726.6 AET39781.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AET39781.1 - 0.09 11.8 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Got1 PF04178.7 AET39782.1 - 5e-18 65.3 14.9 5.9e-18 65.0 10.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 AET39782.1 - 0.018 14.0 3.6 0.025 13.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DnaJ_CXXCXGXG PF00684.14 AET39783.1 - 7.3e-05 22.7 8.1 0.0095 15.9 0.7 2.5 2 0 0 2 2 2 2 DnaJ central domain Cytochrom_c3_2 PF14537.1 AET39783.1 - 0.64 10.4 6.2 3.9 7.8 0.0 2.9 2 1 0 2 2 2 0 Cytochrome c3 GTP_cyclohydroI PF01227.17 AET39784.1 - 2.9e-75 251.5 0.4 3.4e-75 251.2 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 AET39784.1 - 9.5e-05 22.2 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein OmpH PF03938.9 AET39784.1 - 0.023 14.6 1.1 0.65 9.9 0.1 2.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 AET39785.1 - 1.4e-53 181.7 0.3 1.3e-52 178.5 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39785.1 - 3.9e-24 85.1 0.5 1e-19 70.6 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AET39785.1 - 0.0016 17.4 0.2 0.016 14.1 0.1 2.2 1 1 0 1 1 1 1 Kinase-like SRP1_TIP1 PF00660.12 AET39786.1 - 7.1e-09 35.4 0.0 1.5e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Seripauperin and TIP1 family Trypan_PARP PF05887.6 AET39786.1 - 0.00025 20.8 8.9 0.00025 20.8 6.1 1.5 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Pex14_N PF04695.8 AET39786.1 - 0.032 14.2 1.1 0.032 14.2 0.8 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NESP55 PF06390.7 AET39786.1 - 0.1 11.9 7.4 0.15 11.4 5.1 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pheromone PF08015.6 AET39786.1 - 0.25 12.2 2.7 0.91 10.3 1.9 2.1 1 1 0 1 1 1 0 Fungal mating-type pheromone PRCC PF10253.4 AET39786.1 - 0.75 10.4 6.1 1.1 9.8 4.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DEAD PF00270.24 AET39787.1 - 1.5e-44 151.4 1.2 5.3e-44 149.6 0.1 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET39787.1 - 5.1e-22 77.5 0.0 1.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AET39787.1 - 2.6e-20 71.6 0.2 5.1e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AET39787.1 - 0.0013 18.6 0.2 0.0029 17.4 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 AET39787.1 - 0.0035 16.6 0.0 0.012 14.9 0.0 1.6 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.1 AET39787.1 - 0.065 13.3 1.7 0.38 10.8 1.0 2.5 2 1 0 2 2 2 0 AAA domain tRNA-synt_1g PF09334.6 AET39788.1 - 3.6e-146 486.8 0.0 4.6e-146 486.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 AET39788.1 - 3.9e-37 127.3 0.1 8e-37 126.3 0.1 1.5 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 AET39788.1 - 2.3e-10 39.1 0.1 0.00013 20.1 0.0 2.6 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AET39788.1 - 0.077 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Kdo PF06293.9 AET39789.1 - 3.2e-09 36.1 0.0 5.6e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 AET39789.1 - 3.3e-07 29.7 0.0 4.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AET39789.1 - 1e-05 25.4 0.0 0.0001 22.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AET39789.1 - 0.00011 21.6 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.15 AET39789.1 - 0.0016 17.6 0.1 0.0025 17.0 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.12 AET39789.1 - 0.0027 16.8 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1679 PF07914.6 AET39789.1 - 0.043 12.4 0.1 0.056 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF4135 PF13575.1 AET39789.1 - 0.066 12.1 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Choline_kinase PF01633.15 AET39789.1 - 0.096 12.2 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aminotran_4 PF01063.14 AET39790.1 - 1.3e-20 73.9 0.0 2.2e-20 73.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV NAD_binding_6 PF08030.7 AET39791.1 - 4.2e-21 75.4 0.0 7e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AET39791.1 - 7.8e-18 64.2 0.0 1.5e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 AET39791.1 - 4.2e-15 55.9 18.4 4.2e-15 55.9 12.8 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Candida_ALS_N PF11766.3 AET39792.1 - 1.6e-63 213.9 6.8 1.6e-63 213.9 4.7 2.1 2 0 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding Mito_carr PF00153.22 AET39793.1 - 2.1e-52 174.7 3.5 3.3e-19 68.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TBSV_P22 PF03558.8 AET39794.1 - 0.052 12.9 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 TBSV core protein P21/P22 SPC12 PF06645.8 AET39795.1 - 6.1e-21 74.0 0.1 7.2e-21 73.7 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Tetraspannin PF00335.15 AET39795.1 - 0.0025 17.1 0.4 0.0028 16.9 0.3 1.0 1 0 0 1 1 1 1 Tetraspanin family Biotin_lipoyl PF00364.17 AET39796.1 - 3.2e-17 61.9 2.5 5.5e-17 61.1 0.4 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 AET39796.1 - 1.7e-05 24.3 0.0 4.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.1 AET39796.1 - 0.082 13.2 0.2 0.3 11.4 0.1 2.0 2 0 0 2 2 2 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 AET39796.1 - 0.1 12.2 0.4 0.32 10.6 0.1 1.9 1 1 1 2 2 2 0 Biotin-lipoyl like ATP-sulfurylase PF01747.12 AET39797.1 - 4.7e-87 290.8 0.0 6.6e-87 290.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 AET39797.1 - 4.3e-52 175.7 0.0 7.6e-52 174.9 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Memo PF01875.12 AET39798.1 - 4.8e-81 271.6 0.0 5.6e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein EIF_2_alpha PF07541.7 AET39799.1 - 1.6e-42 143.8 1.3 6.7e-42 141.8 0.2 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 AET39799.1 - 6.7e-15 54.9 1.7 1.4e-14 53.8 1.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 AET39799.1 - 0.12 12.3 0.5 0.33 10.9 0.3 1.8 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 AA_permease PF00324.16 AET39800.1 - 4.3e-129 430.9 39.0 5.3e-129 430.6 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET39800.1 - 1.1e-31 109.8 43.0 1.4e-31 109.4 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2269 PF10027.4 AET39800.1 - 6 6.6 13.0 0.58 9.9 1.2 3.4 3 1 0 3 3 3 0 Predicted integral membrane protein (DUF2269) NUC153 PF08159.7 AET39801.1 - 1.5e-14 53.2 4.8 1.5e-14 53.2 3.3 4.1 4 0 0 4 4 4 2 NUC153 domain DUF2406 PF10295.4 AET39802.1 - 2.2e-25 88.9 0.0 3.8e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aminotran_1_2 PF00155.16 AET39803.1 - 3.2e-61 207.2 0.0 4.2e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Fungal_trans_2 PF11951.3 AET39804.1 - 2.1e-14 52.9 2.2 1.8e-12 46.6 1.5 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET39804.1 - 3.6e-07 29.9 11.5 8.4e-07 28.7 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alb1 PF09135.6 AET39805.1 - 1.3e-23 83.6 12.1 1.9e-23 83.1 8.4 1.2 1 0 0 1 1 1 1 Alb1 DUF2062 PF09835.4 AET39806.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Aldedh PF00171.17 AET39807.1 - 3.1e-181 602.7 1.0 3.5e-181 602.5 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LRR_4 PF12799.2 AET39808.1 - 1.4e-13 50.1 45.7 4.1e-08 32.6 1.1 8.1 4 2 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AET39808.1 - 1.6e-09 37.3 40.8 0.0002 21.0 0.6 6.4 3 2 5 8 8 8 4 Leucine rich repeat LRR_1 PF00560.28 AET39808.1 - 0.00036 20.1 40.3 0.21 11.7 0.1 10.8 8 4 3 11 11 11 4 Leucine Rich Repeat LRR_7 PF13504.1 AET39808.1 - 0.014 15.4 28.9 3.1 8.3 0.0 10.1 10 1 0 10 10 10 0 Leucine rich repeat LRR_9 PF14580.1 AET39808.1 - 0.014 14.9 7.6 2.5 7.6 0.1 4.1 3 1 1 4 4 4 0 Leucine-rich repeat LRR_6 PF13516.1 AET39808.1 - 0.017 15.1 38.6 4 7.8 0.5 10.1 6 3 4 10 10 10 0 Leucine Rich repeat Med15 PF09606.5 AET39809.1 - 1.4e-05 23.5 39.2 1.4e-05 23.5 27.2 1.9 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 AET39809.1 - 0.43 8.7 38.9 0.02 13.1 22.2 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Vps39_1 PF10366.4 AET39809.1 - 0.92 9.5 6.0 3.7 7.6 3.5 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Kelch_3 PF13415.1 AET39810.1 - 2.8e-10 40.0 0.7 0.00066 19.7 0.0 5.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.1 AET39810.1 - 3.5e-10 39.4 3.0 2.8e-06 26.9 0.2 5.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 AET39810.1 - 2.4e-08 33.7 7.1 0.096 12.6 0.0 6.4 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 AET39810.1 - 6e-08 32.5 6.9 0.015 15.4 0.1 6.3 8 0 0 8 8 8 3 Kelch motif Kelch_2 PF07646.10 AET39810.1 - 7.5e-07 28.6 2.8 0.017 14.8 0.1 5.0 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 AET39810.1 - 2.7e-06 26.7 6.4 0.055 13.0 0.2 4.7 5 0 0 5 5 5 3 Kelch motif GDI PF00996.13 AET39811.1 - 1.4e-54 185.0 0.0 2e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Ribosomal_L7Ae PF01248.21 AET39812.1 - 1.2e-23 82.3 0.2 1.5e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 AET39812.1 - 0.0075 16.2 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) Rad1 PF02144.11 AET39813.1 - 3.2e-69 232.7 0.6 4.1e-69 232.4 0.4 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Peroxin-22 PF12827.2 AET39814.1 - 1.3e-18 66.7 0.1 1.7e-18 66.4 0.1 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family FixQ PF05545.6 AET39814.1 - 0.027 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ CH PF00307.26 AET39815.1 - 1.8e-12 47.2 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain AMP-binding PF00501.23 AET39816.1 - 7.8e-94 314.4 0.0 9.5e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AET39816.1 - 3.1e-18 66.4 0.1 3.2e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 AET39817.1 - 8.7e-10 38.3 10.2 8.7e-10 38.3 7.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 AET39818.1 - 1.3e-10 40.9 14.3 2.7e-10 39.9 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Miro PF08477.8 AET39819.1 - 5.6e-42 143.0 0.0 9.3e-21 74.5 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 AET39819.1 - 1.7e-29 100.8 1.0 3.1e-29 100.0 0.7 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 AET39819.1 - 1.5e-28 98.4 0.0 1e-27 95.7 0.0 2.2 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 AET39819.1 - 2.7e-24 85.3 0.0 3.8e-11 42.6 0.0 3.0 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 AET39819.1 - 1e-08 35.1 0.0 0.0006 19.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 AET39819.1 - 5.5e-08 32.8 1.4 0.0049 16.9 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AET39819.1 - 5.8e-07 28.3 8.5 0.0071 15.5 0.8 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 AET39819.1 - 2.2e-06 27.0 6.2 0.0086 15.8 0.4 3.3 3 0 0 3 3 2 2 EF-hand domain Dynamin_N PF00350.18 AET39819.1 - 2.5e-06 27.4 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 AET39819.1 - 4e-06 26.3 0.0 0.33 10.3 0.0 3.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AET39819.1 - 3e-05 24.1 0.0 0.088 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AET39819.1 - 5.8e-05 23.1 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_5 PF13202.1 AET39819.1 - 0.0001 21.4 7.7 0.066 12.5 1.7 2.6 2 0 0 2 2 2 2 EF hand MobB PF03205.9 AET39819.1 - 0.0004 20.0 0.1 0.1 12.3 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 AET39819.1 - 0.00064 19.3 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AET39819.1 - 0.00081 18.9 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 AET39819.1 - 0.0011 18.6 0.0 0.11 12.1 0.0 2.7 3 0 0 3 3 2 1 NACHT domain RNA_helicase PF00910.17 AET39819.1 - 0.0013 18.8 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 AET39819.1 - 0.0018 18.5 0.0 1.3 9.3 0.0 3.2 3 1 0 3 3 2 1 AAA domain DUF258 PF03193.11 AET39819.1 - 0.004 16.3 0.0 0.011 14.9 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function, DUF258 Septin PF00735.13 AET39819.1 - 0.0065 15.5 0.0 0.14 11.1 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_29 PF13555.1 AET39819.1 - 0.0088 15.5 0.0 0.65 9.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 AET39819.1 - 0.011 15.2 0.0 8 5.9 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 AET39819.1 - 0.011 15.1 0.0 5.3 6.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_32 PF13654.1 AET39819.1 - 0.021 13.5 0.0 0.27 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AET39819.1 - 0.021 14.7 0.1 6 6.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 AET39819.1 - 0.03 14.6 0.0 0.94 9.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 AET39819.1 - 0.041 13.5 0.0 5.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase FeoB_N PF02421.13 AET39819.1 - 0.098 11.9 0.0 12 5.1 0.0 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.1 AET39819.1 - 0.13 13.0 0.0 11 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Proteasome PF00227.21 AET39820.1 - 4.4e-52 176.1 0.0 5.4e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AET39820.1 - 9.8e-12 43.9 0.0 9.8e-12 43.9 0.0 2.3 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Mto2_bdg PF12808.2 AET39821.1 - 0.00022 21.2 7.6 0.00022 21.2 5.3 4.1 5 0 0 5 5 5 1 Micro-tubular organiser Mto1 C-term Mto2-binding region eIF2A PF08662.6 AET39822.1 - 4e-31 108.2 0.3 3.4e-27 95.4 0.3 4.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 AET39822.1 - 6.5e-09 35.3 0.2 1.8e-08 33.8 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET39822.1 - 1.2e-05 25.1 0.5 3.6e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET39822.1 - 3.4e-05 23.7 0.1 9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lac_bphage_repr PF06543.7 AET39822.1 - 0.77 9.3 4.1 0.22 11.0 0.3 2.0 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor BolA PF01722.13 AET39823.1 - 1.4e-16 60.2 0.0 1.7e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein BolA PF01722.13 AET39824.1 - 8.8e-24 83.2 0.7 1.2e-23 82.8 0.5 1.2 1 0 0 1 1 1 1 BolA-like protein HTH_5 PF01022.15 AET39824.1 - 0.061 13.0 0.1 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family PDEase_I PF00233.14 AET39825.1 - 3.3e-46 157.9 0.6 2.7e-45 154.9 0.4 2.0 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 AET39825.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 HD domain SAM_2 PF07647.12 AET39826.1 - 2.4e-07 30.5 0.1 5.5e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AET39826.1 - 5.3e-06 26.5 0.3 2.5e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF3453 PF11935.3 AET39827.1 - 1.7e-59 201.1 0.1 3.9e-59 199.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) CBFD_NFYB_HMF PF00808.18 AET39828.1 - 8.3e-23 80.2 2.1 1.4e-22 79.5 1.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AET39828.1 - 1.3e-16 60.4 0.2 1.8e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 AET39828.1 - 0.00097 18.9 0.2 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 AET39828.1 - 0.075 12.9 0.3 0.13 12.2 0.1 1.4 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF3791 PF12668.2 AET39828.1 - 0.096 12.3 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) PX PF00787.19 AET39829.1 - 4.8e-21 74.6 0.1 7.1e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 PX domain COPIIcoated_ERV PF07970.7 AET39830.1 - 1.3e-72 244.0 0.9 1.6e-72 243.7 0.6 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AET39830.1 - 1.5e-29 101.8 0.1 3.2e-29 100.7 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RhoGEF PF00621.15 AET39831.1 - 3e-38 131.4 5.7 3e-38 131.4 3.9 2.0 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.6 AET39831.1 - 6.3e-35 119.1 1.7 1.1e-34 118.2 0.4 2.2 2 0 0 2 2 2 1 CDC24 Calponin PH_10 PF15411.1 AET39831.1 - 5.7e-22 78.0 0.3 2.1e-21 76.2 0.2 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 AET39831.1 - 3.1e-06 26.7 1.0 1.4e-05 24.6 0.3 2.4 2 0 0 2 2 2 1 PB1 domain PH PF00169.24 AET39831.1 - 0.00054 20.1 0.4 0.0017 18.5 0.2 1.9 1 0 0 1 1 1 1 PH domain ETF_QO PF05187.8 AET39832.1 - 6.3e-41 138.8 0.0 1.1e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 AET39832.1 - 7.9e-10 38.1 0.1 0.0002 20.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AET39832.1 - 3.2e-06 27.0 0.1 7.2e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AET39832.1 - 5.6e-06 25.4 0.4 0.012 14.4 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 AET39832.1 - 1.2e-05 24.4 0.0 0.04 12.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 AET39832.1 - 7.5e-05 21.3 0.3 0.0011 17.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 AET39832.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AET39832.1 - 0.0015 18.9 0.8 1.7 9.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AET39832.1 - 0.0017 18.1 0.3 0.017 14.9 0.2 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 AET39832.1 - 0.0019 17.3 0.2 0.0091 15.0 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.2 AET39832.1 - 0.0046 17.3 0.5 0.012 16.0 0.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.1 AET39832.1 - 0.0087 16.1 0.1 0.019 15.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AET39832.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 AET39832.1 - 0.085 11.9 0.0 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase Lycopene_cycl PF05834.7 AET39832.1 - 0.098 11.5 0.2 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 AET39832.1 - 0.21 10.1 0.4 0.59 8.6 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Cupin_8 PF13621.1 AET39834.1 - 6.7e-44 150.2 0.0 1.8e-39 135.7 0.0 2.2 1 1 0 2 2 2 2 Cupin-like domain JmjC PF02373.17 AET39834.1 - 0.0032 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 AET39834.1 - 0.089 12.0 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein Cyto_heme_lyase PF01265.12 AET39835.1 - 1.7e-68 230.9 0.0 2e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase MNE1 PF13762.1 AET39837.1 - 1.8e-17 63.7 1.8 1.8e-17 63.7 1.3 2.4 2 0 0 2 2 2 1 Mitochondrial splicing apparatus component SHS2_Rpb7-N PF03876.12 AET39838.1 - 6.8e-13 48.5 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 FNIP PF05725.7 AET39838.1 - 0.13 12.2 0.4 0.73 9.8 0.1 2.1 2 0 0 2 2 2 0 FNIP Repeat Fungal_trans PF04082.13 AET39839.1 - 7.5e-13 47.9 1.3 1.6e-12 46.8 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET39839.1 - 0.00012 21.9 8.6 0.00026 20.8 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CagX PF03524.10 AET39839.1 - 0.074 12.3 4.4 0.14 11.4 3.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TGS PF02824.16 AET39840.1 - 4.5e-22 77.6 0.0 8.4e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AET39840.1 - 1.1e-16 60.7 0.1 3e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AET39840.1 - 5.5e-09 35.4 0.0 1.5e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AET39840.1 - 0.0029 17.4 0.4 1.9 8.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 AET39840.1 - 0.0059 15.4 0.1 0.012 14.4 0.1 1.5 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 AET39840.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein HLH PF00010.21 AET39842.1 - 9.3e-22 76.4 0.1 1.7e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mem_trans PF03547.13 AET39842.1 - 0.014 13.6 1.7 0.018 13.3 1.2 1.2 1 0 0 1 1 1 0 Membrane transport protein Ribosomal_60s PF00428.14 AET39842.1 - 0.1 12.9 4.1 4.5 7.7 0.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spt5_N PF11942.3 AET39842.1 - 0.11 13.1 3.9 0.27 11.8 2.7 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 AET39842.1 - 0.21 9.5 9.9 0.33 8.9 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein IMS PF00817.15 AET39843.1 - 1.3e-33 115.9 0.1 2.5e-33 114.9 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AET39843.1 - 1.8e-13 50.4 0.0 5.2e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 AET39843.1 - 3.3e-09 36.7 0.0 1.2e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AET39843.1 - 1.9e-07 30.8 0.1 7.7e-07 28.8 0.0 2.2 3 0 0 3 3 3 1 twin BRCT domain IMS_HHH PF11798.3 AET39843.1 - 0.025 14.5 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 IMS family HHH motif HHH PF00633.18 AET39843.1 - 0.03 14.0 0.0 0.071 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4414 PF14377.1 AET39843.1 - 0.043 13.7 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) DUF1805 PF08827.6 AET39843.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) HHH_5 PF14520.1 AET39843.1 - 0.054 13.6 0.0 0.59 10.3 0.0 1.8 1 1 1 2 2 2 0 Helix-hairpin-helix domain PK PF00224.16 AET39844.1 - 1.4e-167 556.6 0.3 1.7e-167 556.3 0.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 AET39844.1 - 5.9e-30 103.2 0.0 1.9e-29 101.5 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 AET39844.1 - 1.2e-05 24.3 0.2 3.2e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Mis12 PF05859.7 AET39845.1 - 2.6e-43 147.3 0.3 4.5e-43 146.5 0.2 1.4 1 0 0 1 1 1 1 Mis12 protein CorA PF01544.13 AET39845.1 - 0.72 8.8 4.5 0.28 10.1 0.4 2.2 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein SWIRM PF04433.12 AET39846.1 - 1.4e-12 47.5 0.0 2.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain UDP-g_GGTase PF06427.6 AET39847.1 - 1.3e-08 34.3 0.2 3e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Sds3 PF08598.6 AET39847.1 - 0.077 12.5 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Sds3-like RNase_P_Rpp14 PF01900.14 AET39848.1 - 2.3e-33 114.3 0.2 2.8e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family SKIP_SNW PF02731.10 AET39849.1 - 1.6e-50 170.6 1.4 1.6e-50 170.6 1.0 2.1 2 0 0 2 2 2 1 SKIP/SNW domain CorA PF01544.13 AET39851.1 - 1.5e-09 37.3 1.9 2.2e-09 36.7 1.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein vATP-synt_E PF01991.13 AET39852.1 - 4.4e-56 189.3 13.1 5.2e-56 189.0 9.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DNA_pol_A PF00476.15 AET39853.1 - 6.7e-101 337.6 0.0 1.3e-100 336.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 AET39853.1 - 8.9e-07 28.5 0.3 0.00044 19.7 0.5 2.5 1 1 0 2 2 2 2 3'-5' exonuclease DUF2040 PF09745.4 AET39854.1 - 8.1e-08 32.1 12.2 8.1e-08 32.1 8.5 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) PLRV_ORF5 PF01690.12 AET39854.1 - 6.9 5.6 9.3 8.2 5.4 6.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Bap31 PF05529.7 AET39854.1 - 8.3 5.8 9.5 34 3.8 6.6 2.1 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4557 PF15101.1 AET39855.1 - 0.16 11.7 15.2 0.19 11.5 8.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Zip PF02535.17 AET39855.1 - 0.17 10.8 1.7 0.28 10.1 1.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 AET39855.1 - 0.25 10.1 36.9 0.45 9.3 25.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Band_3_cyto PF07565.8 AET39855.1 - 1.1 8.7 10.6 2.9 7.3 7.3 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF106 PF01956.11 AET39855.1 - 2.2 7.8 7.4 5 6.6 5.1 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF4175 PF13779.1 AET39855.1 - 2.3 5.8 30.2 0.098 10.3 16.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) BRF1 PF07741.8 AET39855.1 - 7.2 6.9 14.4 0.3 11.3 4.7 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Gti1_Pac2 PF09729.4 AET39855.1 - 9.7 6.0 14.3 0.52 10.1 5.0 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Synaptobrevin PF00957.16 AET39856.1 - 1.3e-31 108.0 1.6 1.5e-31 107.8 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin Rifin_STEVOR PF02009.11 AET39856.1 - 0.14 11.8 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family PRT_C PF08372.5 AET39856.1 - 0.16 11.4 1.0 0.21 11.1 0.7 1.2 1 1 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF912 PF06024.7 AET39856.1 - 0.21 11.6 0.7 0.27 11.3 0.5 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Myosin_head PF00063.16 AET39857.1 - 1.7e-259 862.6 11.2 1.7e-259 862.6 7.8 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 AET39857.1 - 1.6e-33 114.6 2.6 8.3e-33 112.4 1.8 2.4 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 AET39857.1 - 3.2e-05 23.1 19.3 0.46 10.2 0.1 6.3 6 0 0 6 6 6 2 IQ calmodulin-binding motif AAA_22 PF13401.1 AET39857.1 - 0.003 17.6 2.4 0.0073 16.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain ADIP PF11559.3 AET39857.1 - 0.0045 16.9 7.2 0.0045 16.9 5.0 3.3 2 1 0 3 3 2 1 Afadin- and alpha -actinin-Binding DivIC PF04977.10 AET39857.1 - 0.0055 16.1 33.1 0.14 11.6 0.3 6.3 5 1 1 6 6 5 3 Septum formation initiator Myosin_N PF02736.14 AET39857.1 - 0.0063 16.1 0.1 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Saccharop_dh_N PF04455.7 AET39857.1 - 0.028 14.5 1.4 0.41 10.7 0.1 2.9 2 0 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region DBI_PRT PF02277.12 AET39857.1 - 0.042 12.9 0.2 0.095 11.7 0.0 1.6 2 0 0 2 2 2 0 Phosphoribosyltransferase Reo_sigmaC PF04582.7 AET39857.1 - 0.048 12.8 13.9 0.076 12.1 4.0 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 AET39857.1 - 0.076 12.7 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain FlaC_arch PF05377.6 AET39857.1 - 0.11 12.3 13.3 1.2 9.0 0.4 4.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 AET39857.1 - 0.15 12.4 22.0 0.13 12.5 0.4 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF972) DUF948 PF06103.6 AET39857.1 - 1.3 8.9 16.2 0.053 13.3 1.7 3.9 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.7 AET39857.1 - 3.8 5.8 3.9 6.1 5.1 2.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hph PF13694.1 AET39858.1 - 1.3e-05 25.3 0.7 5.3e-05 23.3 0.5 1.8 1 1 0 1 1 1 1 Sec63/Sec62 complex-interacting family HrpB7 PF09486.5 AET39858.1 - 0.21 11.4 3.7 0.25 11.2 0.4 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Saw1 PF11561.3 AET39859.1 - 4.2e-45 153.8 0.1 5.1e-45 153.5 0.1 1.1 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Aldedh PF00171.17 AET39860.1 - 3.5e-10 38.8 1.2 5.7e-07 28.2 0.1 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1542 PF07564.6 AET39860.1 - 0.0032 17.4 2.0 0.65 10.0 0.4 3.0 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1542) Med15_fungi PF05397.7 AET39860.1 - 0.065 13.2 0.5 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 15 E1-E2_ATPase PF00122.15 AET39861.1 - 6.1e-18 64.7 0.6 1e-17 63.9 0.4 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AET39861.1 - 1.8e-17 64.1 1.7 6.5e-17 62.3 1.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AET39861.1 - 4.3e-12 46.8 5.1 3e-09 37.6 1.9 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AET39861.1 - 1.7e-09 37.4 0.0 4.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AET39861.1 - 0.001 18.7 1.1 0.009 15.6 0.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AET39861.1 - 0.049 13.8 0.3 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribosomal_L28e PF01778.12 AET39862.1 - 2.9e-33 114.7 1.9 2.9e-33 114.7 1.3 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 AET39862.1 - 4.6e-31 106.9 15.6 4.6e-31 106.9 10.8 2.7 2 1 0 2 2 2 1 Mak16 protein C-terminal region Ribosomal_L24e PF01246.15 AET39862.1 - 0.029 14.2 0.1 0.029 14.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L24e PYC_OADA PF02436.13 AET39862.1 - 0.14 11.5 0.8 0.27 10.6 0.6 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain Ribosomal_L24e PF01246.15 AET39864.1 - 9.6e-30 102.2 1.9 9.6e-30 102.2 1.3 2.5 3 0 0 3 3 3 1 Ribosomal protein L24e zf-FCS PF06467.9 AET39864.1 - 0.44 10.2 4.5 0.85 9.3 3.1 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Pam16 PF03656.8 AET39865.1 - 8.4e-06 25.6 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 AET39865.1 - 1.2e-05 24.9 0.1 1.6e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain SMC_Nse1 PF07574.8 AET39866.1 - 1.1e-54 185.1 2.7 1.4e-54 184.7 1.8 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 AET39866.1 - 5.3e-09 35.9 10.3 5.3e-09 35.9 7.1 1.7 2 0 0 2 2 2 1 RING-like domain SapB_1 PF05184.10 AET39866.1 - 0.52 10.1 3.8 15 5.5 0.1 3.0 2 1 0 2 2 2 0 Saposin-like type B, region 1 Response_reg PF00072.19 AET39867.1 - 6.3e-21 74.4 0.0 4.6e-13 49.1 0.1 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Adaptin_N PF01602.15 AET39868.1 - 1.9e-90 303.6 22.7 2.3e-90 303.4 15.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AET39868.1 - 9.2e-08 32.2 0.0 0.065 13.5 0.0 4.2 4 1 1 5 5 5 2 HEAT repeats Arm PF00514.18 AET39868.1 - 0.032 14.0 1.7 13 5.7 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat WASH-7_C PF14746.1 AET39868.1 - 0.035 13.7 1.0 0.13 11.8 0.2 2.3 1 1 1 2 2 2 0 WASH complex subunit 7, C-terminal FANCI_S2 PF14676.1 AET39868.1 - 1.6 8.6 11.2 29 4.5 0.1 4.2 3 1 2 5 5 5 0 FANCI solenoid 2 CMS1 PF14617.1 AET39869.1 - 9.8e-16 57.5 7.6 1.4e-14 53.7 5.3 2.7 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit KCNQ_channel PF03520.9 AET39869.1 - 0.0065 15.8 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel VitD-bind_III PF09164.5 AET39869.1 - 0.027 14.0 0.1 0.11 12.1 0.0 2.1 1 1 0 1 1 1 0 Vitamin D binding protein, domain III Glyco_hydro_92 PF07971.7 AET39870.1 - 3.6e-141 471.2 2.9 5.2e-141 470.7 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Bac_rhamnosid PF05592.6 AET39870.1 - 0.023 12.9 0.1 0.036 12.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase MFS_1 PF07690.11 AET39871.1 - 1.7e-29 102.6 17.7 1.7e-29 102.6 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0546 PF10639.4 AET39871.1 - 2.1 8.2 6.6 4.4 7.1 0.6 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 Adaptin_N PF01602.15 AET39872.1 - 4.5e-90 302.4 13.3 5.3e-90 302.2 9.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AET39872.1 - 2.8e-11 43.5 3.2 0.00014 22.0 0.1 4.8 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 AET39872.1 - 6.6e-10 38.2 1.7 0.037 14.1 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 AET39872.1 - 0.00034 20.9 3.1 1.4 9.5 0.0 4.5 4 2 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.2 AET39872.1 - 0.0057 16.5 12.6 0.0061 16.4 0.2 4.7 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Med26 PF08711.6 AET39872.1 - 0.015 14.8 0.1 1.6 8.2 0.1 3.0 3 0 0 3 3 3 0 TFIIS helical bundle-like domain UNC45-central PF11701.3 AET39872.1 - 0.029 13.9 1.9 0.47 10.0 0.0 3.0 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Gpi16 PF04113.9 AET39873.1 - 2e-188 626.9 0.1 2.6e-188 626.6 0.1 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Elong_Iki1 PF10483.4 AET39874.1 - 6.5e-79 265.1 0.4 7.4e-79 265.0 0.3 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 CRT10 PF08728.5 AET39875.1 - 6.4e-173 576.5 8.6 7.6e-173 576.2 6.0 1.0 1 0 0 1 1 1 1 CRT10 APC8 PF04049.8 AET39876.1 - 3.8e-40 136.9 2.7 7.6e-40 135.9 1.8 1.4 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 AET39876.1 - 3.8e-25 86.3 15.4 3.3e-05 23.2 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 AET39876.1 - 6.3e-25 86.6 13.9 2.4e-09 36.6 0.3 5.5 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 AET39876.1 - 7.8e-21 72.2 14.2 0.00018 21.1 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 AET39876.1 - 5.4e-17 60.2 19.6 0.0012 18.4 0.0 7.0 6 1 2 8 8 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 AET39876.1 - 9.1e-15 53.8 0.7 0.023 15.3 0.0 6.3 4 1 3 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 AET39876.1 - 1e-13 50.9 14.1 3.9e-05 23.4 0.1 5.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 AET39876.1 - 3.5e-10 40.2 2.5 2.4e-05 24.8 0.0 5.6 4 1 3 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 AET39876.1 - 5.8e-09 35.9 20.5 0.00055 20.0 1.7 5.1 3 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AET39876.1 - 6.2e-08 31.8 3.5 0.064 13.0 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat ChAPs PF09295.5 AET39876.1 - 7.4e-07 28.2 0.1 2.3e-06 26.6 0.0 1.8 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 AET39876.1 - 1.3e-06 28.6 0.5 0.0057 16.9 0.2 4.5 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 AET39876.1 - 2.2e-06 27.4 14.3 0.0065 16.5 0.1 6.1 7 1 1 8 8 6 2 Tetratricopeptide repeat BTAD PF03704.12 AET39876.1 - 6.9e-06 26.4 0.5 0.00018 21.8 0.3 2.8 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 AET39876.1 - 2.5e-05 23.4 1.7 0.0011 18.0 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 AET39876.1 - 0.00023 21.3 11.4 3.1 8.4 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 AET39876.1 - 0.00042 20.1 3.1 0.076 12.8 0.7 3.5 3 1 0 4 4 4 1 Tetratricopeptide repeat HTH_Tnp_Mu_2 PF09039.6 AET39876.1 - 0.013 15.2 0.2 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain TPR_10 PF13374.1 AET39876.1 - 0.063 13.2 0.0 3.5 7.7 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Sel1 PF08238.7 AET39876.1 - 0.21 12.2 9.2 44 4.8 0.0 5.2 5 0 0 5 5 4 0 Sel1 repeat THP2 PF09432.5 AET39877.1 - 3.7e-42 143.2 1.4 3.7e-42 143.2 1.0 1.7 3 0 0 3 3 3 1 Tho complex subunit THP2 Mod_r PF07200.8 AET39877.1 - 0.00075 19.4 3.8 0.0029 17.5 0.2 2.2 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein BpuJI_N PF11564.3 AET39877.1 - 0.004 16.1 0.7 0.0057 15.6 0.5 1.3 1 1 0 1 1 1 1 Restriction endonuclease BpuJI - N terminal DUF1804 PF08822.6 AET39877.1 - 0.0065 16.2 0.1 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1804) CHASE3 PF05227.8 AET39877.1 - 0.15 11.6 0.8 1.2 8.8 0.0 2.6 3 1 0 3 3 3 0 CHASE3 domain UBN2_2 PF14227.1 AET39877.1 - 0.43 10.1 5.0 0.12 11.9 0.3 2.2 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type GTP1_OBG PF01018.17 AET39878.1 - 1.9e-34 118.5 3.3 7.8e-25 87.3 2.2 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 AET39878.1 - 1.3e-20 73.4 0.0 2.7e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 AET39878.1 - 8e-13 47.9 0.0 1.6e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 AET39878.1 - 1.1e-10 41.0 0.0 3.1e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 AET39878.1 - 4.1e-05 24.0 0.0 0.0001 22.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 AET39878.1 - 0.00041 19.8 0.0 0.0095 15.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 AET39878.1 - 0.0039 15.9 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 ArgK protein Ras PF00071.17 AET39878.1 - 0.026 13.9 0.0 0.088 12.2 0.0 1.8 2 0 0 2 2 2 0 Ras family SRPRB PF09439.5 AET39878.1 - 0.03 13.5 0.0 0.12 11.6 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DEAD PF00270.24 AET39879.1 - 2.6e-39 134.3 0.2 3.5e-37 127.4 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AET39879.1 - 1e-27 95.8 0.1 1.8e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET39879.1 - 0.0092 15.8 0.0 0.028 14.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2702 PF10863.3 AET39880.1 - 5.2e-45 152.6 8.0 5.2e-45 152.6 5.6 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2702) PRA-CH PF01502.13 AET39880.1 - 0.14 11.7 1.3 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase Rotamase PF00639.16 AET39880.1 - 1.5 9.5 11.3 0.69 10.6 1.3 3.0 2 1 1 3 3 3 0 PPIC-type PPIASE domain DUF2175 PF09943.4 AET39880.1 - 2.2 8.3 5.6 4.4 7.4 3.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) FAM60A PF15396.1 AET39880.1 - 3.2 7.4 12.0 0.11 12.2 4.4 1.4 2 0 0 2 2 2 0 Protein Family FAM60A DUF668 PF05003.7 AET39880.1 - 8.2 6.7 7.2 12 6.1 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF668) NMD3 PF04981.8 AET39881.1 - 5.3e-76 254.8 1.3 9.6e-76 253.9 0.9 1.4 1 0 0 1 1 1 1 NMD3 family HypA PF01155.14 AET39881.1 - 1.3 8.7 4.5 34 4.1 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 AET39881.1 - 1.9 8.4 6.4 2.3 8.1 2.4 2.4 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 AET39881.1 - 1.9 8.3 6.9 22 4.9 3.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 AET39881.1 - 5 6.9 7.7 3.1 7.6 0.0 3.3 2 1 1 3 3 3 0 Zinc-ribbon Bromodomain PF00439.20 AET39882.1 - 8.9e-25 86.4 1.4 2.1e-24 85.2 1.0 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 AET39882.1 - 4.3e-10 39.6 0.5 4.9e-09 36.2 0.2 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AET39882.1 - 2.5e-08 33.8 0.1 4.7e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AET39882.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AET39882.1 - 0.0047 16.8 0.1 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Proteasome PF00227.21 AET39883.1 - 1.1e-54 184.6 0.1 1.4e-54 184.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AET39883.1 - 2.2e-13 49.2 0.1 4e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Spc97_Spc98 PF04130.8 AET39884.1 - 6.9e-92 308.5 4.8 1.5e-91 307.3 3.4 1.5 1 1 0 1 1 1 1 Spc97 / Spc98 family Enolase_C PF00113.17 AET39885.1 - 2.3e-153 509.4 0.0 3.1e-153 508.9 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 AET39885.1 - 7.2e-59 197.4 0.5 1.2e-58 196.7 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 AET39885.1 - 0.0026 18.2 0.0 0.0072 16.8 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 AET39885.1 - 0.042 12.7 0.1 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Ctr PF04145.10 AET39886.1 - 2.8e-22 79.2 15.4 1.1e-11 44.9 0.8 2.1 1 1 1 2 2 2 2 Ctr copper transporter family Spore_YhaL PF14147.1 AET39886.1 - 0.059 12.8 1.2 0.059 12.8 0.8 1.9 2 0 0 2 2 2 0 Sporulation protein YhaL DUF1286 PF06939.6 AET39886.1 - 0.78 9.9 5.1 1.3 9.2 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1286) FMO-like PF00743.14 AET39887.1 - 5.3e-38 130.5 0.2 4.3e-32 111.0 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AET39887.1 - 9.8e-19 68.2 0.0 2.1e-18 67.1 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AET39887.1 - 4.4e-16 59.0 0.7 7.1e-14 51.8 0.1 3.4 2 2 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AET39887.1 - 1.8e-10 41.0 0.0 1.1e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AET39887.1 - 1.2e-09 37.5 0.8 5.8e-05 22.1 0.1 3.1 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 AET39887.1 - 3e-08 33.5 0.1 9.8e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AET39887.1 - 3.9e-08 32.5 0.3 0.0018 17.2 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 AET39887.1 - 5.5e-06 25.7 0.0 0.056 12.5 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 AET39887.1 - 9.1e-06 24.9 0.1 0.00025 20.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 AET39887.1 - 6.3e-05 21.6 0.1 0.0034 15.9 0.0 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 AET39887.1 - 7.1e-05 23.1 0.4 0.15 12.4 0.0 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AET39887.1 - 0.002 18.1 0.0 0.51 10.4 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 AET39887.1 - 0.0089 15.1 0.0 0.071 12.2 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AET39887.1 - 0.01 15.5 0.4 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 AET39887.1 - 0.012 14.5 0.0 0.22 10.3 0.0 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein IlvN PF07991.7 AET39887.1 - 0.017 14.5 0.2 0.68 9.2 0.1 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 AET39887.1 - 0.04 13.4 0.2 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 AET39887.1 - 0.063 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 AET39887.1 - 0.065 13.2 0.1 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 AET39887.1 - 0.083 12.6 0.7 8.6 6.0 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 AET39887.1 - 0.089 11.4 1.1 8.2 4.9 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_7 PF13241.1 AET39887.1 - 0.1 12.8 0.0 7.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 AET39887.1 - 0.14 12.1 0.7 3.6 7.5 0.0 2.4 2 1 0 2 2 2 0 NADH(P)-binding GIDA PF01134.17 AET39887.1 - 0.17 10.7 0.0 11 4.7 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF836 PF05768.9 AET39887.1 - 0.25 11.6 1.2 3.3 8.0 0.2 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Erv26 PF04148.8 AET39888.1 - 1.3e-80 269.7 6.1 1.7e-80 269.3 4.2 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 CD20 PF04103.10 AET39888.1 - 0.037 13.9 3.0 0.059 13.3 0.3 2.0 2 0 0 2 2 2 0 CD20-like family 7TM_GPCR_Srh PF10318.4 AET39888.1 - 0.18 10.5 9.5 0.048 12.4 4.2 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF2189 PF09955.4 AET39888.1 - 2.5 8.0 7.1 31 4.5 4.9 2.4 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) 6PGD PF00393.14 AET39890.1 - 1.2e-132 441.5 0.0 1.5e-132 441.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AET39890.1 - 3.4e-47 160.3 0.0 4.9e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AET39890.1 - 0.025 14.6 0.3 0.12 12.4 0.0 2.3 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Mito_carr PF00153.22 AET39891.1 - 2.2e-61 203.5 0.0 1.9e-23 81.9 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein XPG_N PF00752.12 AET39893.1 - 5.2e-32 110.1 0.0 1.5e-31 108.6 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 AET39893.1 - 7.5e-24 83.6 0.0 2.4e-23 82.0 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 AET39893.1 - 0.001 18.5 0.4 0.0032 16.9 0.0 2.0 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.15 AET39893.1 - 0.0049 17.0 0.0 0.023 14.9 0.0 2.1 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Ribosomal_L7Ae PF01248.21 AET39894.1 - 4.7e-28 96.5 0.7 6.8e-28 96.0 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AET39894.1 - 0.00028 20.7 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF3519 PF12033.3 AET39895.1 - 0.72 10.0 7.7 0.52 10.5 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) Adaptin_N PF01602.15 AET39897.1 - 2.5e-103 346.2 14.8 3.7e-103 345.6 10.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 AET39897.1 - 9.8e-57 190.2 0.0 2.2e-56 189.1 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 AET39897.1 - 7.8e-52 174.6 2.3 1.3e-51 173.9 0.1 2.5 3 0 0 3 3 3 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 AET39897.1 - 1e-09 38.5 4.6 0.00046 20.4 0.0 4.9 2 1 3 5 5 5 4 HEAT repeats NolV PF06635.7 AET39897.1 - 0.022 13.8 0.1 0.21 10.7 0.0 2.3 2 1 1 3 3 3 0 Nodulation protein NolV HEAT PF02985.17 AET39897.1 - 0.046 13.8 0.0 6.7 7.0 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Ribosomal_L5_C PF00673.16 AET39898.1 - 5.7e-21 74.0 0.0 2.1e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AET39898.1 - 0.0016 18.2 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 GLE1 PF07817.8 AET39899.1 - 6.2e-85 284.1 0.0 6.2e-85 284.1 0.0 2.6 2 1 1 3 3 3 1 GLE1-like protein MAP7 PF05672.6 AET39899.1 - 0.14 11.5 40.0 0.24 10.7 27.8 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 AET39899.1 - 3.4 6.9 41.1 6.8 6.0 28.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.7 AET39899.1 - 3.8 7.3 15.8 5.6 6.8 11.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF572 PF04502.8 AET39899.1 - 8.6 5.4 26.5 13 4.8 18.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Flavokinase PF01687.12 AET39900.1 - 1.2e-33 115.6 0.0 1.5e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Porphobil_deam PF01379.15 AET39901.1 - 5.8e-84 280.3 0.0 7.5e-84 279.9 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 AET39901.1 - 9.5e-20 70.4 0.2 1.6e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF1938 PF09153.5 AET39901.1 - 0.12 12.1 0.2 6.7 6.6 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1938) Aconitase PF00330.15 AET39902.1 - 5.3e-68 229.5 0.0 1e-43 149.5 0.0 2.3 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AET39902.1 - 8.9e-27 93.7 0.0 1.6e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Reticulon PF02453.12 AET39903.1 - 9.2e-40 136.0 5.5 1.2e-39 135.6 3.8 1.1 1 0 0 1 1 1 1 Reticulon DUF2547 PF10818.3 AET39903.1 - 0.03 14.9 0.1 0.068 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Aminotran_1_2 PF00155.16 AET39904.1 - 3e-74 250.1 0.0 1.4e-73 247.9 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AET39904.1 - 8.1e-08 30.9 0.0 1.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AET39904.1 - 2.7e-06 26.3 0.0 6.1e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AET39904.1 - 0.0028 16.7 0.1 0.061 12.3 0.0 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 AET39904.1 - 0.044 12.9 0.1 0.13 11.4 0.1 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase DAHP_synth_1 PF00793.15 AET39906.1 - 3.7e-97 324.2 0.0 4.4e-97 324.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cellulase PF00150.13 AET39907.1 - 2.1e-12 46.8 5.4 3.6e-12 46.0 3.7 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PRP1_N PF06424.7 AET39908.1 - 1.6e-28 99.7 1.5 3.8e-28 98.4 0.1 2.4 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 AET39908.1 - 3.3e-26 89.3 0.0 0.00085 19.7 0.0 9.7 6 4 3 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 AET39908.1 - 3.3e-14 52.9 0.1 0.036 14.4 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 AET39908.1 - 3.2e-13 49.1 0.2 0.012 15.2 0.0 6.8 4 2 3 7 7 7 3 TPR repeat TPR_16 PF13432.1 AET39908.1 - 1.4e-12 47.9 0.0 0.25 12.0 0.5 6.7 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 AET39908.1 - 3.2e-07 29.7 0.4 0.028 14.3 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 AET39908.1 - 4.2e-06 26.6 0.1 0.094 12.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 AET39908.1 - 4.3e-06 26.5 0.2 16 5.9 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 AET39908.1 - 0.00032 20.9 2.0 2.6 8.6 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AET39908.1 - 0.0024 17.5 3.1 13 5.8 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 AET39908.1 - 0.021 14.4 0.1 0.31 10.7 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 AET39908.1 - 0.028 14.5 0.1 28 4.9 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF413 PF04219.7 AET39908.1 - 0.068 12.9 0.7 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF TPR_7 PF13176.1 AET39908.1 - 0.078 12.8 0.0 3.3 7.7 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 AET39909.1 - 8.4e-22 77.2 0.6 8.1e-21 74.0 0.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET39909.1 - 1.1e-06 28.4 12.0 2.1e-06 27.5 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.7 AET39910.1 - 1.8e-59 201.0 0.0 3.5e-59 200.1 0.0 1.4 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 AET39910.1 - 1.4e-09 37.8 0.0 0.0095 15.8 0.0 4.0 3 1 1 4 4 4 3 Arylesterase Transposase_23 PF03017.9 AET39910.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 TNP1/EN/SPM transposase CHCH PF06747.8 AET39911.1 - 9.4e-07 28.5 10.6 0.00015 21.5 0.3 2.7 2 1 1 3 3 3 3 CHCH domain UPF0203 PF05254.7 AET39911.1 - 3.7e-05 23.4 5.2 0.006 16.4 0.4 2.4 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0203) COX6B PF02297.12 AET39911.1 - 4.9e-05 23.2 6.2 0.00064 19.6 0.3 2.1 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 AET39911.1 - 0.008 16.1 10.3 0.31 11.0 2.1 2.7 1 1 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 AET39911.1 - 0.0098 15.6 10.8 0.064 13.0 2.4 2.4 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like ALMT PF11744.3 AET39911.1 - 0.016 13.8 0.2 0.019 13.6 0.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter UCR_hinge PF02320.11 AET39911.1 - 3.7 7.5 8.8 3.2 7.7 1.2 2.5 1 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF1752 PF08550.5 AET39912.1 - 4.8e-11 42.0 0.9 1.2e-10 40.7 0.6 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CAF-1_p150 PF11600.3 AET39912.1 - 0.0027 17.1 25.7 0.0027 17.1 17.8 3.7 4 1 1 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4175 PF13779.1 AET39912.1 - 0.19 9.4 61.8 0.31 8.7 42.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pex2_Pex12 PF04757.9 AET39913.1 - 7.9e-19 67.9 11.4 1.6e-18 67.0 7.9 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 AET39913.1 - 0.094 12.7 9.2 0.43 10.6 6.3 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps54 PF07928.7 AET39914.1 - 0.00078 19.5 0.1 0.00078 19.5 0.1 2.4 3 0 0 3 3 3 1 Vps54-like protein Menin PF05053.8 AET39914.1 - 0.002 16.4 7.2 0.0033 15.6 5.0 1.3 1 0 0 1 1 1 1 Menin Myb_DNA-bind_6 PF13921.1 AET39915.1 - 8.5e-19 67.4 20.2 1.5e-15 56.9 1.6 4.4 3 2 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AET39915.1 - 2e-17 62.9 18.3 2e-09 37.3 0.5 5.8 5 1 0 5 5 5 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 AET39915.1 - 0.22 11.7 12.2 1.3 9.2 1.5 4.0 2 2 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.1 AET39915.1 - 3.3 7.8 18.8 0.24 11.5 0.9 5.0 4 2 1 5 5 5 0 Myb/SANT-like DNA-binding domain Ribosomal_S17 PF00366.15 AET39916.1 - 1.9e-30 104.7 4.0 3e-30 104.0 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 YolD PF08863.5 AET39918.1 - 0.031 14.1 0.3 0.1 12.4 0.2 1.9 1 0 0 1 1 1 0 YolD-like protein DUF2058 PF09831.4 AET39918.1 - 9.3 6.0 13.7 3.9 7.3 4.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) tRNA-synt_2b PF00587.20 AET39919.1 - 7.4e-34 116.8 0.0 2.2e-33 115.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AET39919.1 - 4.1e-21 75.0 10.2 4.1e-21 75.0 7.1 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 AET39919.1 - 0.14 10.5 6.6 0.21 9.9 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1049 PF06305.6 AET39919.1 - 5.4 6.5 6.2 0.26 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Mgm101p PF06420.7 AET39921.1 - 1.4e-89 297.9 0.0 2e-89 297.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 PMT PF02366.13 AET39922.1 - 4.8e-79 265.1 24.8 1e-78 264.1 17.2 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AET39922.1 - 1.4e-25 89.9 0.1 2.4e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 MIR domain DHHA2 PF02833.9 AET39923.1 - 1.1e-19 70.8 0.1 1.7e-19 70.2 0.1 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 AET39923.1 - 5.5e-14 52.0 0.6 1.9e-13 50.2 0.1 1.9 2 0 0 2 2 2 1 DHH family KH_5 PF13184.1 AET39923.1 - 0.056 13.2 0.2 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 NusA-like KH domain HECT_2 PF09814.4 AET39924.1 - 2.2e-65 220.7 1.5 2.4e-65 220.5 1.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF1255 PF06865.6 AET39924.1 - 0.0038 17.4 0.0 0.0071 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1255) DUF4182 PF13790.1 AET39924.1 - 0.14 11.9 0.1 0.14 11.9 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4182) Dpoe2NT PF12213.3 AET39925.1 - 0.05 13.5 1.6 0.8 9.6 0.0 3.6 2 1 1 3 3 3 0 DNA polymerases epsilon N terminal Homoserine_dh PF00742.14 AET39926.1 - 2.3e-54 183.7 0.0 3.3e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 AET39926.1 - 3.6e-18 66.0 0.0 5.7e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AET39926.1 - 0.045 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Nif11 PF07862.6 AET39926.1 - 0.83 9.6 3.3 13 5.8 0.0 3.5 3 1 1 4 4 4 0 Nitrogen fixation protein of unknown function DUF3608 PF12257.3 AET39927.1 - 8.1e-143 474.3 0.4 1.3e-142 473.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 AET39927.1 - 1.9e-26 91.5 0.1 5.3e-26 90.1 0.1 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NIR_SIR PF01077.17 AET39928.1 - 3e-49 166.3 0.0 3.9e-45 153.0 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 AET39928.1 - 4.8e-27 94.7 0.0 1.2e-26 93.3 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.12 AET39928.1 - 6.4e-26 89.7 0.1 1.6e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Chalcone PF02431.10 AET39929.1 - 1.5e-47 161.5 0.0 2.2e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase DUF2454 PF10521.4 AET39930.1 - 7.2e-63 212.2 5.7 9.8e-63 211.7 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Sybindin PF04099.7 AET39930.1 - 0.083 12.6 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Sybindin-like family zf-Tim10_DDP PF02953.10 AET39931.1 - 1.1e-20 72.7 6.0 1.2e-20 72.4 4.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger WAC_Acf1_DNA_bd PF10537.4 AET39931.1 - 0.036 14.2 0.1 0.046 13.8 0.1 1.1 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF2481 PF10654.4 AET39931.1 - 0.07 12.8 0.2 9.5 5.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2481) Post_transc_reg PF13797.1 AET39931.1 - 0.087 12.4 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Post-transcriptional regulator DUF1767 PF08585.7 AET39931.1 - 0.11 12.7 1.0 0.27 11.5 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1767) Sec2p PF06428.6 AET39932.1 - 0.84 9.5 4.5 0.6 9.9 0.5 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p RIX1 PF08167.7 AET39933.1 - 4.1e-43 146.9 3.9 9.4e-43 145.7 2.7 1.7 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Pribosyltran PF00156.22 AET39934.1 - 2e-13 50.1 0.9 2.1e-12 46.8 0.6 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SGL PF08450.7 AET39935.1 - 0.0023 17.3 0.0 0.011 15.1 0.0 2.1 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region TIP120 PF08623.5 AET39935.1 - 0.046 13.3 0.5 0.11 12.0 0.4 1.6 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) IBN_N PF03810.14 AET39936.1 - 4.3e-17 61.7 0.0 7.6e-15 54.5 0.0 3.4 2 0 0 2 2 2 2 Importin-beta N-terminal domain MDM31_MDM32 PF08118.6 AET39938.1 - 2.4e-278 923.5 6.5 2.8e-278 923.3 4.5 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins PIR PF00399.14 AET39939.1 - 4.8e-11 41.5 10.4 2.9e-05 23.2 0.8 2.9 2 0 0 2 2 2 2 Yeast PIR protein repeat PIR PF00399.14 AET39940.1 - 3.2e-43 143.6 88.9 2.3e-08 33.0 2.1 8.1 8 0 0 8 8 8 7 Yeast PIR protein repeat HCV_NS5a_1a PF08300.8 AET39940.1 - 0.087 12.7 0.1 36 4.3 0.0 3.3 1 1 2 3 3 3 0 Hepatitis C virus non-structural 5a zinc finger domain RC-P840_PscD PF10657.4 AET39940.1 - 0.19 11.5 4.6 21 4.9 0.1 3.5 1 1 5 6 6 6 0 Photosystem P840 reaction centre protein PscD Phage_tube PF04985.9 AET39940.1 - 0.7 9.3 3.6 14 5.0 0.1 2.3 1 1 1 2 2 2 0 Phage tail tube protein FII ATP-synt_J PF04911.7 AET39942.1 - 5.5e-27 92.9 0.2 6e-27 92.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.15 AET39943.1 - 1e-25 89.8 0.0 2.4e-24 85.3 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AET39943.1 - 0.016 14.2 0.0 0.037 12.9 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_hydro_47 PF01532.15 AET39944.1 - 2.3e-133 445.1 0.2 2.6e-133 444.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ctf8 PF09696.5 AET39945.1 - 3.1e-26 91.5 0.0 4.3e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Ctf8 DUF2296 PF10058.4 AET39946.1 - 1.3e-16 60.0 1.3 2.2e-16 59.3 0.9 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) IncA PF04156.9 AET39946.1 - 0.00045 19.8 2.9 0.00093 18.8 2.0 1.5 1 0 0 1 1 1 1 IncA protein Spore_III_AF PF09581.5 AET39946.1 - 0.0061 16.4 0.8 0.01 15.7 0.5 1.4 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) DUF1610 PF07754.6 AET39946.1 - 0.02 14.9 0.5 0.02 14.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) V-SNARE PF05008.10 AET39946.1 - 0.067 13.3 8.0 0.082 13.0 4.0 2.4 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DASH_Duo1 PF08651.5 AET39946.1 - 0.19 11.3 5.0 0.72 9.4 0.7 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 OmpH PF03938.9 AET39946.1 - 0.25 11.2 5.2 0.43 10.4 3.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Peptidase_C74 PF12387.3 AET39946.1 - 0.69 9.0 5.7 1.9 7.6 0.5 2.2 1 1 1 2 2 2 0 Pestivirus NS2 peptidase DUF964 PF06133.6 AET39946.1 - 0.8 9.7 11.7 0.26 11.3 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF964) DUF4047 PF13256.1 AET39946.1 - 0.85 9.5 5.0 1.5 8.7 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Uds1 PF15456.1 AET39946.1 - 0.85 9.6 8.2 4.9 7.1 0.3 2.7 2 1 0 3 3 3 0 Up-regulated During Septation FliD_N PF02465.13 AET39946.1 - 1.2 9.5 8.7 0.29 11.5 2.2 2.3 2 1 1 3 3 2 0 Flagellar hook-associated protein 2 N-terminus SlyX PF04102.7 AET39946.1 - 2.2 8.6 8.8 5.7 7.3 1.1 3.0 2 1 1 3 3 3 0 SlyX Seryl_tRNA_N PF02403.17 AET39946.1 - 6.8 6.7 11.1 5.5 7.0 3.0 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NAC PF01849.13 AET39947.1 - 1.8e-20 72.1 1.0 5.1e-20 70.7 0.2 1.9 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 AET39947.1 - 4.8e-05 23.0 0.2 9.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain BRE1 PF08647.6 AET39947.1 - 0.04 13.9 1.8 0.51 10.3 0.0 2.8 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase GatB_Yqey PF02637.13 AET39947.1 - 0.067 12.9 1.0 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 GatB domain Shikimate_DH PF01488.15 AET39947.1 - 0.14 12.2 2.6 0.17 11.9 0.1 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Wbp11 PF09429.5 AET39947.1 - 0.15 12.0 1.7 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 WW domain binding protein 11 DivIVA PF05103.8 AET39947.1 - 3.2 7.8 6.2 0.82 9.7 1.9 1.8 2 0 0 2 2 2 0 DivIVA protein DUF3306 PF11748.3 AET39947.1 - 3.2 8.4 7.2 8 7.1 4.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RVT_1 PF00078.22 AET39948.1 - 4.3e-23 81.7 0.0 8.4e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 AET39948.1 - 2.9e-19 69.3 0.0 7e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 AET39948.1 - 4.8e-06 26.2 1.2 9.3e-06 25.3 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Peptidase_A2B PF12384.3 AET39948.1 - 0.00019 20.8 0.5 0.00051 19.4 0.1 1.9 2 0 0 2 2 2 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 AET39948.1 - 0.0014 19.1 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 AET39948.1 - 0.0024 17.2 0.1 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger PIR PF00399.14 AET39949.1 - 9e-08 31.2 1.0 3.4e-07 29.3 0.7 2.1 1 0 0 1 1 1 1 Yeast PIR protein repeat zf-RING_2 PF13639.1 AET39950.1 - 5.3e-05 22.9 4.2 0.00014 21.6 2.9 1.8 1 0 0 1 1 1 1 Ring finger domain Tropomodulin PF03250.9 AET39950.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Tropomodulin zf-C3HC4 PF00097.20 AET39950.1 - 0.011 15.3 2.4 0.029 14.0 1.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Flagellin_N PF00669.15 AET39950.1 - 0.039 13.7 0.2 0.69 9.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region PaREP1 PF05942.6 AET39950.1 - 0.042 13.7 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family Peptidase_S64 PF08192.6 AET39951.1 - 1.4e-251 836.7 0.1 1.6e-251 836.5 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S64 6PF2K PF01591.13 AET39952.1 - 3.3e-80 268.3 0.0 4.6e-80 267.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AET39952.1 - 2.9e-31 108.6 0.1 7.7e-31 107.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AET39952.1 - 4.9e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AET39952.1 - 0.012 16.3 0.1 0.12 13.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain Vps35 PF03635.12 AET39953.1 - 1.2e-281 936.3 21.7 1.5e-281 936.0 15.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Pam17 PF08566.5 AET39954.1 - 9.1e-70 233.8 0.0 1.2e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 MFS_1 PF07690.11 AET39954.1 - 0.0062 15.3 0.1 0.0077 14.9 0.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.2 AET39955.1 - 4.6e-07 29.4 0.3 4.6e-07 29.4 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AET39955.1 - 1.8e-06 27.4 0.1 9.8e-06 25.0 0.1 2.3 1 0 0 1 1 1 1 F-box domain Zn_clus PF00172.13 AET39956.1 - 1.2e-09 37.9 7.1 2.6e-09 36.8 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_polI_A34 PF08208.6 AET39957.1 - 6.4e-44 149.9 21.6 8.8e-44 149.5 14.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 AET39957.1 - 0.48 10.1 5.8 0.84 9.3 4.0 1.4 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 AET39957.1 - 0.5 10.2 17.0 0.76 9.6 11.8 1.5 1 1 0 1 1 1 0 GAGA binding protein-like family Dala_Dala_lig_N PF01820.16 AET39957.1 - 4.1 7.7 6.1 36 4.7 3.4 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus TFIIE_beta PF02186.10 AET39958.1 - 3.5e-23 81.3 0.1 6.9e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain CRAL_TRIO PF00650.15 AET39961.1 - 4.8e-28 97.6 0.2 3e-27 95.0 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AET39961.1 - 0.00012 22.0 0.3 0.00042 20.3 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Tim17 PF02466.14 AET39963.1 - 5.2e-33 113.8 4.5 6.1e-33 113.5 3.1 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RNA_pol_Rpb4 PF03874.11 AET39964.1 - 1.2e-35 122.0 4.1 2.2e-35 121.2 2.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb4 RXT2_N PF08595.6 AET39964.1 - 0.002 17.9 2.9 0.0043 16.8 2.0 1.6 1 0 0 1 1 1 1 RXT2-like, N-terminal UTP15_C PF09384.5 AET39964.1 - 0.56 9.8 5.9 0.54 9.9 0.3 2.8 1 1 2 3 3 3 0 UTP15 C terminal IncFII_repA PF02387.10 AET39964.1 - 2.1 7.4 5.7 3.6 6.6 3.9 1.5 1 1 0 1 1 1 0 IncFII RepA protein family Glyco_transf_15 PF01793.11 AET39965.1 - 1.1e-134 448.5 13.9 1.4e-134 448.2 9.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L1 PF00687.16 AET39966.1 - 1.3e-45 155.4 0.5 1.6e-45 155.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Peptidase_C36 PF05415.6 AET39966.1 - 0.077 12.8 0.1 0.81 9.6 0.0 2.2 2 0 0 2 2 2 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase TUDOR PF00567.19 AET39966.1 - 0.2 11.4 2.5 8.3 6.2 0.0 2.8 2 1 1 3 3 3 0 Tudor domain DEAD PF00270.24 AET39967.1 - 8.2e-45 152.3 1.1 2.6e-44 150.7 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET39967.1 - 9e-28 95.9 0.2 1.6e-26 91.9 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET39967.1 - 0.00032 20.6 0.1 0.0041 16.9 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AET39967.1 - 0.00033 20.3 0.3 0.005 16.5 0.1 2.5 2 1 0 2 2 2 1 Part of AAA domain DUF1253 PF06862.7 AET39967.1 - 0.0011 17.4 0.2 0.91 7.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) CMS1 PF14617.1 AET39967.1 - 0.022 13.8 0.0 0.052 12.6 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 AET39967.1 - 0.038 13.5 0.0 0.08 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 AET39967.1 - 0.043 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Glyco_transf_8 PF01501.15 AET39968.1 - 6.4e-31 107.5 0.3 1.3e-30 106.5 0.2 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Ribosomal_S21e PF01249.13 AET39969.1 - 3.6e-40 135.7 0.0 3.9e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA_U5-meth_tr PF05958.6 AET39970.1 - 5.2e-22 78.0 0.1 9.3e-21 73.8 0.1 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 AET39970.1 - 9.4e-11 41.5 0.0 2.7e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 AET39970.1 - 7.2e-10 38.5 0.0 1.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 AET39970.1 - 1.3e-06 29.0 0.0 2.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AET39970.1 - 6.3e-06 25.5 0.1 1.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 AET39970.1 - 1.4e-05 24.5 0.0 5.6e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 AET39970.1 - 2.4e-05 23.9 1.3 4.8e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 AET39970.1 - 5.5e-05 23.1 0.0 9.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AET39970.1 - 6.6e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 AET39970.1 - 0.00071 19.2 0.4 0.0022 17.6 0.0 2.1 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_25 PF13649.1 AET39970.1 - 0.002 18.4 0.0 0.0081 16.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 AET39970.1 - 0.0021 17.1 0.5 0.0053 15.8 0.0 1.9 2 1 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 AET39970.1 - 0.0032 16.6 0.0 0.0068 15.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AET39970.1 - 0.0069 16.8 0.0 0.033 14.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 AET39970.1 - 0.058 12.9 0.1 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 PAP2 PF01569.16 AET39971.1 - 1.1e-14 54.2 0.9 1.1e-14 54.2 0.6 2.1 3 0 0 3 3 3 1 PAP2 superfamily Mito_carr PF00153.22 AET39972.1 - 7.4e-63 208.2 2.8 7.2e-22 76.9 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Solute_trans_a PF03619.11 AET39973.1 - 1.5e-82 277.0 14.0 1.8e-82 276.7 9.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1119 PF06550.6 AET39973.1 - 0.028 13.5 1.6 0.05 12.7 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1119) mIF3 PF14877.1 AET39974.1 - 2.7e-54 183.2 7.8 5.6e-54 182.2 5.4 1.5 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Wound_ind PF08186.6 AET39974.1 - 7.6 6.5 8.0 15 5.6 2.2 2.9 2 0 0 2 2 2 0 Wound-inducible basic protein family CPSase_L_D2 PF02786.12 AET39975.1 - 2.8e-116 386.2 0.4 3.5e-83 278.0 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 AET39975.1 - 7.9e-47 158.0 0.0 2e-46 156.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 AET39975.1 - 1.1e-44 152.2 0.0 2.3e-44 151.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 AET39975.1 - 7.5e-42 142.3 0.0 2.1e-41 140.8 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 AET39975.1 - 2e-40 137.2 0.3 1.7e-20 73.1 0.0 3.4 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 AET39975.1 - 4.7e-39 132.9 0.1 1.1e-38 131.7 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AET39975.1 - 7.3e-34 117.1 0.1 1.5e-21 76.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 AET39975.1 - 7.8e-31 107.0 0.0 5.3e-30 104.3 0.0 2.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 AET39975.1 - 7.3e-25 87.3 0.1 5e-14 51.7 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 AET39975.1 - 5.8e-21 74.2 0.0 3.8e-20 71.6 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 AET39975.1 - 4.2e-16 58.9 1.8 1.1e-09 38.0 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 AET39975.1 - 3.6e-14 52.4 0.1 6.7e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 AET39975.1 - 9.6e-08 31.7 0.4 1e-06 28.3 0.1 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 AET39975.1 - 8.7e-06 25.3 0.0 0.0005 19.5 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 AET39975.1 - 0.029 13.8 0.0 0.092 12.1 0.0 1.8 1 0 0 1 1 1 0 DJ-1/PfpI family HMG_box PF00505.14 AET39976.1 - 2.3e-31 107.8 4.2 5.6e-15 55.3 0.6 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 AET39976.1 - 3.5e-23 81.7 3.7 8e-13 48.5 0.9 2.3 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.7 AET39976.1 - 3.1e-05 23.5 0.1 0.0044 16.6 0.0 2.6 2 1 0 2 2 2 2 CHDNT (NUC034) domain DUF1074 PF06382.6 AET39976.1 - 0.062 13.2 0.3 0.094 12.6 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1074) TrkH PF02386.11 AET39977.1 - 1.3e-135 451.5 17.9 7.2e-135 449.1 6.5 2.1 2 0 0 2 2 2 2 Cation transport protein Pkinase PF00069.20 AET39978.1 - 9e-55 185.6 0.0 9e-55 185.6 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET39978.1 - 1.6e-37 129.0 0.0 2.7e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TAT_signal PF10518.4 AET39979.1 - 0.066 13.2 0.1 0.095 12.7 0.0 1.2 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence PNGaseA PF12222.3 AET39980.1 - 1.9e-47 162.1 8.9 5.1e-45 154.1 6.2 2.2 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A zf-H2C2 PF09337.5 AET39981.1 - 1.9e-20 71.9 4.7 4.5e-20 70.7 3.2 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 AET39981.1 - 0.00011 22.2 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 AET39981.1 - 0.049 13.7 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AET39981.1 - 0.086 12.9 0.1 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AET39981.1 - 0.087 12.7 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Big_3_4 PF13754.1 AET39981.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) GCD14 PF08704.5 AET39982.1 - 2.1e-76 256.7 0.0 5.1e-42 144.0 0.1 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 AET39982.1 - 0.00038 19.5 0.1 0.0012 17.9 0.0 1.8 3 0 0 3 3 3 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 AET39982.1 - 0.00048 20.6 0.0 0.001 19.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET39982.1 - 0.00055 19.9 0.0 0.00096 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF3748 PF12566.3 AET39982.1 - 0.0021 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3748) GCD14_N PF14801.1 AET39982.1 - 0.0072 15.8 0.7 0.095 12.2 0.0 2.7 3 0 0 3 3 3 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.14 AET39982.1 - 0.041 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 AET39982.1 - 0.055 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AET39982.1 - 0.099 12.3 0.0 0.33 10.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Acyl-CoA_dh_1 PF00441.19 AET39983.1 - 3e-18 66.3 0.0 9.4e-18 64.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AET39983.1 - 1.1e-09 37.5 0.0 2.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 AET39983.1 - 0.0011 19.4 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain LSM PF01423.17 AET39984.1 - 1.1e-13 50.4 0.1 1.7e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 LSM domain PUF PF00806.14 AET39984.1 - 0.043 13.3 0.1 0.097 12.2 0.1 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DUF1687 PF07955.6 AET39985.1 - 6.8e-23 81.1 0.0 8.1e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) DUF2413 PF10310.4 AET39986.1 - 2.2e-96 323.4 12.1 2.6e-96 323.1 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) SecIII_SopE_N PF05364.9 AET39986.1 - 0.07 12.9 0.1 0.27 11.0 0.0 2.1 1 1 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus Alb1 PF09135.6 AET39987.1 - 2.3e-19 70.0 7.8 2.3e-19 70.0 5.4 1.5 1 1 0 1 1 1 1 Alb1 DUF2578 PF10843.3 AET39987.1 - 0.77 9.4 4.1 0.22 11.1 0.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2578) Pap_E4 PF02711.9 AET39987.1 - 1.7 9.5 4.5 2.7 8.8 0.3 2.4 1 1 1 2 2 2 0 E4 protein Ribul_P_3_epim PF00834.14 AET39988.1 - 5.2e-70 234.6 0.0 6.5e-70 234.3 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 AET39988.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 AET39988.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 PcrB family QRPTase_C PF01729.14 AET39988.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain NAP PF00956.13 AET39989.1 - 6e-81 271.1 7.4 6e-81 271.1 5.1 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Glyco_hydro_28 PF00295.12 AET39992.1 - 1.2e-79 267.6 17.0 1.5e-79 267.3 11.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 AET39992.1 - 4.5e-10 39.5 19.7 4.5e-10 39.5 13.7 2.8 2 2 1 3 3 3 2 Right handed beta helix region NosD PF05048.8 AET39992.1 - 0.00057 19.1 15.4 0.00057 19.1 10.7 2.5 2 1 1 3 3 3 2 Periplasmic copper-binding protein (NosD) Innate_immun PF12782.2 AET39993.1 - 0.25 10.5 7.8 0.37 9.9 5.4 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Zip PF02535.17 AET39993.1 - 4.5 6.1 8.0 6.1 5.7 5.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Pho86 PF11124.3 AET39994.1 - 4.5e-83 278.7 1.2 5.1e-83 278.5 0.8 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Lectin_leg-like PF03388.8 AET39995.1 - 1.8e-16 59.9 0.2 1.8e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Legume-like lectin family His_Phos_1 PF00300.17 AET39996.1 - 5.6e-30 104.5 0.0 7.7e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SUN PF03856.8 AET39997.1 - 1.1e-97 326.2 13.3 1.8e-97 325.5 9.2 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-MYND PF01753.13 AET39997.1 - 0.13 12.1 2.2 0.28 11.0 1.5 1.5 1 0 0 1 1 1 0 MYND finger DUF4215 PF13948.1 AET39997.1 - 2.7 8.2 8.9 0.25 11.6 2.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4215) Mg_trans_NIPA PF05653.9 AET39999.1 - 1.4e-09 37.3 11.9 3.1e-09 36.2 8.2 1.5 1 1 0 1 1 1 1 Magnesium transporter NIPA RE_R_Pab1 PF09522.5 AET39999.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease ASF1_hist_chap PF04729.8 AET40000.1 - 6.2e-66 220.7 0.1 9.3e-66 220.2 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone BUD22 PF09073.5 AET40000.1 - 3.1 6.7 35.9 3.5 6.5 24.9 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 AET40000.1 - 5.9 4.6 46.4 8.3 4.1 32.1 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 AET40003.1 - 1.6e-50 171.7 0.0 5.6e-50 169.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40003.1 - 2.6e-20 72.6 0.0 5.6e-20 71.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AET40003.1 - 0.001 18.8 0.0 2.2 7.9 0.0 2.7 2 1 0 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 AET40003.1 - 0.0033 16.8 1.4 0.014 14.7 1.0 2.1 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 AET40003.1 - 0.011 14.7 0.0 0.028 13.4 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Actin PF00022.14 AET40004.1 - 1.3e-114 382.7 0.0 1.5e-114 382.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AET40004.1 - 0.0013 17.3 0.0 0.0044 15.6 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein Adap_comp_sub PF00928.16 AET40006.1 - 3.2e-75 252.6 0.2 3.9e-75 252.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pribosyl_synth PF14572.1 AET40007.1 - 7.5e-40 136.6 0.1 1.3e-39 135.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 AET40007.1 - 3.4e-37 126.7 0.0 4.9e-36 122.9 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 AET40007.1 - 7.7e-12 45.0 0.0 2.1e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AET40007.1 - 0.016 14.4 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pkinase PF00069.20 AET40008.1 - 3.9e-58 196.6 0.0 6.9e-58 195.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40008.1 - 6.7e-22 77.8 0.0 1.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40008.1 - 0.0016 17.5 0.0 0.0037 16.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AET40008.1 - 0.14 11.8 0.1 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family ANAPC15 PF15243.1 AET40008.1 - 2.1 8.4 7.8 0.091 12.8 1.4 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF21 PF01595.15 AET40009.1 - 6.3e-32 110.3 0.3 1.1e-31 109.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 AET40009.1 - 2.9e-05 23.7 0.0 0.045 13.5 0.0 2.8 2 0 0 2 2 2 2 CBS domain NAD_Gly3P_dh_N PF01210.18 AET40010.1 - 7.9e-52 175.1 0.0 1.5e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 AET40010.1 - 5.2e-46 156.0 0.1 8.7e-46 155.3 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Semialdhyde_dh PF01118.19 AET40010.1 - 0.0065 16.7 0.0 0.034 14.4 0.0 2.2 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AET40010.1 - 0.026 14.9 0.1 0.76 10.2 0.1 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Arginosuc_synth PF00764.14 AET40011.1 - 2.3e-162 540.4 0.0 2.7e-162 540.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 AET40011.1 - 9.8e-05 21.9 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AET40011.1 - 0.00019 20.8 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 AET40011.1 - 0.00086 17.9 0.1 0.0013 17.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Peptidase_M49 PF03571.10 AET40012.1 - 9.5e-224 743.5 0.0 1.3e-223 743.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 His_Phos_1 PF00300.17 AET40013.1 - 3.7e-41 140.8 0.0 2.5e-40 138.1 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Phos_pyr_kin PF08543.7 AET40014.1 - 2.3e-75 253.0 0.8 2.6e-75 252.8 0.5 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 AET40014.1 - 0.00023 20.3 0.5 0.0022 17.2 0.3 2.2 1 1 1 2 2 2 1 pfkB family carbohydrate kinase HK PF02110.10 AET40014.1 - 0.15 11.2 5.9 0.11 11.7 0.5 2.6 1 1 1 2 2 2 0 Hydroxyethylthiazole kinase family Oxysterol_BP PF01237.13 AET40015.1 - 3.7e-129 430.2 0.0 6.3e-129 429.4 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.2 AET40015.1 - 3.6e-09 36.8 0.1 0.0025 18.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) PH_8 PF15409.1 AET40015.1 - 8.1e-09 35.4 0.1 2.7e-08 33.7 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_5 PF13857.1 AET40015.1 - 2.6e-08 33.8 0.1 0.021 15.0 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AET40015.1 - 3.1e-08 33.9 0.0 0.0054 17.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.24 AET40015.1 - 9.2e-08 32.2 0.1 2.6e-07 30.7 0.1 1.9 1 0 0 1 1 1 1 PH domain Ank PF00023.25 AET40015.1 - 1.9e-06 27.3 0.0 0.13 12.0 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat PH_11 PF15413.1 AET40015.1 - 9e-06 25.9 1.2 9e-06 25.9 0.9 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.1 AET40015.1 - 0.00085 19.3 0.0 2.6 8.5 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Carn_acyltransf PF00755.15 AET40016.1 - 2e-171 571.1 0.0 2.3e-171 570.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Antimicrobial11 PF08106.6 AET40016.1 - 2.8 7.9 6.8 4 7.4 1.1 2.5 2 0 0 2 2 2 0 Formaecin family Pkinase PF00069.20 AET40017.1 - 7.4e-70 235.0 0.4 1.3e-69 234.2 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40017.1 - 4.7e-52 176.6 0.2 7.6e-52 175.9 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40017.1 - 1.7e-09 37.0 0.1 6e-08 31.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.20 AET40018.1 - 2.8e-61 206.9 0.1 3.6e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40018.1 - 1.1e-34 119.6 0.0 5.6e-34 117.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AET40018.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SAICAR_synt PF01259.13 AET40019.1 - 1.3e-96 322.5 0.0 1.5e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase SH3_1 PF00018.23 AET40020.1 - 3.9e-08 32.5 0.2 1.1e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 AET40020.1 - 3.7e-05 23.2 0.1 0.0001 21.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain ResIII PF04851.10 AET40020.1 - 0.3 10.8 3.6 0.77 9.5 2.5 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HEAT_EZ PF13513.1 AET40021.1 - 1.6e-22 79.3 4.3 3.1e-10 40.2 0.0 7.7 8 1 1 9 9 9 3 HEAT-like repeat HEAT PF02985.17 AET40021.1 - 3.8e-22 76.3 8.4 0.00029 20.6 0.0 8.6 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 AET40021.1 - 4.9e-19 68.4 0.0 8.4e-06 25.9 0.0 5.1 3 1 3 6 6 6 5 HEAT repeats Cnd1 PF12717.2 AET40021.1 - 1.8e-08 34.4 6.6 0.00062 19.6 0.0 3.8 3 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 AET40021.1 - 6.3e-05 23.2 0.7 2.4 8.5 0.0 4.9 4 1 2 6 6 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AET40021.1 - 0.00026 20.4 1.0 0.28 10.5 0.0 4.1 4 0 0 4 4 4 1 CLASP N terminal RAI16-like PF10257.4 AET40021.1 - 0.1 11.4 5.7 0.62 8.9 0.0 3.6 4 0 0 4 4 4 0 Retinoic acid induced 16-like protein EGF_MSP1_1 PF12946.2 AET40021.1 - 0.18 11.6 2.2 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 MSP1 EGF domain 1 Amidohydro_1 PF01979.15 AET40022.1 - 5.1e-25 88.8 0.0 3.5e-24 86.0 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 AET40022.1 - 1.9e-21 77.3 0.0 4.2e-21 76.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 AET40022.1 - 1.9e-09 37.2 0.5 3.7e-09 36.2 0.3 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 AET40022.1 - 6.9e-08 32.1 0.0 0.00069 18.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family EMP24_GP25L PF01105.19 AET40023.1 - 5.2e-30 104.5 0.5 6.1e-30 104.2 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 AET40024.1 - 1.2e-40 139.2 0.0 6.7e-21 74.6 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AET40024.1 - 3.2e-13 49.3 0.0 8.8e-08 31.5 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AET40024.1 - 0.024 13.6 0.0 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 AET40024.1 - 0.026 14.2 0.0 0.16 11.6 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family PapG_C PF03628.8 AET40024.1 - 0.043 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 PapG chaperone-binding domain Steroid_dh PF02544.11 AET40025.1 - 1.1e-32 112.8 9.5 2e-32 112.0 6.6 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Fibrillarin PF01269.12 AET40026.1 - 1.1e-108 361.3 0.0 1.4e-108 361.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 AET40026.1 - 2e-06 27.4 0.1 3.7e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 AET40026.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Shadoo PF14999.1 AET40026.1 - 5.7 6.8 57.5 2.1 8.2 14.7 3.4 1 1 2 3 3 3 0 Shadow of prion protein, neuroprotective Nuc_sug_transp PF04142.10 AET40027.1 - 5.4e-10 38.7 2.2 1.3e-09 37.5 1.5 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 AET40027.1 - 1e-08 34.5 15.1 1e-08 34.5 10.4 1.4 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 AET40027.1 - 7.5e-06 26.0 28.1 0.0052 16.8 4.5 3.1 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 AET40027.1 - 0.00062 19.9 5.5 0.00062 19.9 3.8 2.9 4 0 0 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 AET40027.1 - 0.026 14.1 24.1 0.2 11.2 5.0 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF914 PF06027.7 AET40027.1 - 0.027 13.3 19.5 0.16 10.8 13.5 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) Multi_Drug_Res PF00893.14 AET40027.1 - 0.14 12.6 9.1 0.12 12.8 1.0 2.8 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF4231 PF14015.1 AET40027.1 - 2.9 7.9 5.9 1.4 8.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) UPF0546 PF10639.4 AET40027.1 - 9.4 6.0 13.6 0.1 12.4 2.2 2.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0546 CYSTM PF12734.2 AET40028.1 - 0.043 13.8 62.6 1.8e+03 -1.0 0.1 5.3 2 1 0 2 2 2 0 Cysteine-rich TM module stress tolerance Pex14_N PF04695.8 AET40028.1 - 4 7.5 11.6 1.6e+02 2.3 8.0 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IRF-2BP1_2 PF11261.3 AET40029.1 - 0.077 12.4 0.2 0.21 11.0 0.2 1.7 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Secretin_N_2 PF07655.8 AET40029.1 - 5.5 7.4 18.4 44 4.5 12.7 2.6 1 1 0 1 1 1 0 Secretin N-terminal domain Prefoldin PF02996.12 AET40030.1 - 1.4e-32 111.8 0.4 2.2e-32 111.2 0.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit Pox_A_type_inc PF04508.7 AET40030.1 - 0.007 16.0 1.8 0.17 11.7 0.0 3.5 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat Spore_YhaL PF14147.1 AET40032.1 - 0.38 10.2 1.9 0.7 9.3 1.3 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL PRP38 PF03371.10 AET40033.1 - 7.6e-47 159.1 0.4 9.9e-47 158.7 0.3 1.0 1 0 0 1 1 1 1 PRP38 family DUF1732 PF08340.6 AET40033.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) LSM PF01423.17 AET40034.1 - 6.2e-18 64.1 0.0 1.1e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AET40034.1 - 0.0003 20.6 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Lzipper-MIP1 PF14389.1 AET40035.1 - 0.0086 16.1 7.0 1.9 8.6 2.8 2.4 2 0 0 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 APG6 PF04111.7 AET40035.1 - 0.052 12.5 10.9 0.0093 15.0 4.6 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 AET40035.1 - 0.28 10.7 14.9 0.1 12.2 7.5 1.9 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 AET40035.1 - 0.5 10.7 14.4 0.47 10.8 1.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 AET40035.1 - 0.55 10.3 10.2 3.7 7.6 1.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 AET40035.1 - 2.6 7.9 19.3 3.5 7.5 10.3 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 AET40035.1 - 2.6 8.1 14.8 0.46 10.5 0.6 3.2 2 2 1 3 3 3 0 DivIVA protein DUF904 PF06005.7 AET40035.1 - 2.9 8.2 20.3 7.3 6.9 6.0 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 AET40035.1 - 7.9 6.0 16.7 5.7 6.4 2.9 3.8 2 1 1 3 3 3 0 Septum formation initiator PCI PF01399.22 AET40036.1 - 3.2e-13 49.9 0.4 3.2e-13 49.9 0.3 2.6 3 1 0 3 3 3 1 PCI domain Metallophos PF00149.23 AET40037.1 - 2.3e-43 147.9 0.1 2.9e-43 147.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AET40037.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2786 PF10979.3 AET40037.1 - 0.073 12.7 0.6 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) E1_DerP2_DerF2 PF02221.10 AET40038.1 - 4.7e-24 85.1 0.0 9.3e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 AET40038.1 - 0.00014 21.8 0.0 0.0003 20.8 0.0 1.5 1 1 0 1 1 1 1 ML-like domain Y_Y_Y PF07495.8 AET40038.1 - 0.06 13.1 0.1 0.77 9.5 0.0 2.6 2 0 0 2 2 2 0 Y_Y_Y domain Sdh5 PF03937.11 AET40039.1 - 7e-24 83.3 0.1 1.1e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase CHCH PF06747.8 AET40040.1 - 1.9e-06 27.6 0.3 2.6e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 AET40040.1 - 0.02 14.6 0.2 0.023 14.4 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CMV_US PF08001.6 AET40040.1 - 0.1 11.6 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 CMV US PAPS_reduct PF01507.14 AET40041.1 - 2.1e-26 92.8 0.0 5.7e-26 91.3 0.0 1.7 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DNA_Packaging_2 PF11123.3 AET40042.1 - 0.075 12.9 0.9 0.27 11.1 0.3 2.2 2 0 0 2 2 2 0 DNA packaging protein MyTH4 PF00784.12 AET40042.1 - 0.14 12.1 2.2 3.8 7.4 0.0 3.0 3 0 0 3 3 3 0 MyTH4 domain Closter_coat PF01785.12 AET40042.1 - 0.22 10.5 3.9 0.13 11.2 0.3 2.2 2 0 0 2 2 2 0 Closterovirus coat protein DUF445 PF04286.7 AET40042.1 - 3.4 7.1 6.3 27 4.1 4.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) FMO-like PF00743.14 AET40043.1 - 2e-15 55.9 3.1 1e-05 23.9 0.1 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AET40043.1 - 1.3e-07 31.9 0.2 0.015 15.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AET40043.1 - 0.021 13.7 0.1 0.36 9.7 0.0 2.9 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AET40043.1 - 0.033 14.0 0.0 0.69 9.7 0.0 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AET40043.1 - 0.051 13.3 3.0 0.097 12.4 0.3 2.7 2 1 1 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 AET40043.1 - 0.11 12.4 2.9 0.12 12.4 0.1 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AET40043.1 - 0.18 10.6 1.2 1.3 7.8 1.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Nuf2 PF03800.9 AET40044.1 - 5.7e-46 156.1 0.3 5.7e-46 156.1 0.2 3.0 3 0 0 3 3 3 1 Nuf2 family HrpB7 PF09486.5 AET40044.1 - 1.3 8.8 11.3 3.2 7.6 1.4 4.1 3 2 2 5 5 5 0 Bacterial type III secretion protein (HrpB7) IncA PF04156.9 AET40044.1 - 2.3 7.7 51.5 1.3 8.6 11.8 3.3 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 AET40044.1 - 3.4 6.2 41.9 0.19 10.3 15.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DASH_Dam1 PF08653.5 AET40044.1 - 5.9 6.7 6.3 9.7 6.0 0.0 4.0 5 0 0 5 5 5 0 DASH complex subunit Dam1 Reo_sigmaC PF04582.7 AET40044.1 - 8.9 5.3 17.6 13 4.8 0.8 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein zf-met PF12874.2 AET40045.1 - 8.6e-07 28.9 1.7 1.7e-06 28.0 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AET40045.1 - 0.035 14.2 0.1 0.075 13.1 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF592 PF04574.8 AET40046.1 - 1.7e-66 222.5 0.4 3.2e-66 221.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.12 AET40046.1 - 1.7e-63 213.5 0.0 2.8e-63 212.8 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 AET40046.1 - 0.0028 17.4 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Paired_CXXCH_1 PF09699.5 AET40046.1 - 0.075 12.5 0.2 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) HLH PF00010.21 AET40047.1 - 1.5e-16 59.7 0.0 2.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MbeD_MobD PF04899.7 AET40047.1 - 0.13 12.2 1.3 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 MbeD/MobD like AAA PF00004.24 AET40048.1 - 1.4e-40 138.5 0.0 2.2e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AET40048.1 - 1.8e-06 28.1 0.2 0.00043 20.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AET40048.1 - 6.8e-06 26.0 0.0 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 AET40048.1 - 1.4e-05 24.1 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 AET40048.1 - 3.6e-05 23.4 0.2 0.00019 21.1 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AET40048.1 - 0.00011 22.1 0.0 0.0023 17.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 AET40048.1 - 0.00089 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AET40048.1 - 0.00096 19.1 0.1 0.0034 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AET40048.1 - 0.0021 17.9 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AET40048.1 - 0.0047 17.7 0.2 0.013 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AET40048.1 - 0.0063 16.8 0.1 0.02 15.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 AET40048.1 - 0.0066 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 AET40048.1 - 0.0074 16.0 0.3 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 AET40048.1 - 0.0095 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 AET40048.1 - 0.01 15.2 1.6 0.23 10.8 0.3 2.3 1 1 0 2 2 2 0 AAA domain AAA_3 PF07726.6 AET40048.1 - 0.011 15.3 0.1 0.028 14.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AET40048.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 AET40048.1 - 0.017 13.8 0.0 0.035 12.8 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.10 AET40048.1 - 0.019 14.6 0.3 0.19 11.3 0.0 2.5 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.17 AET40048.1 - 0.02 13.7 0.0 0.049 12.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 AET40048.1 - 0.03 13.4 0.2 0.41 9.7 0.1 2.4 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 AET40048.1 - 0.03 13.9 0.1 0.32 10.6 0.0 2.2 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 AET40048.1 - 0.03 14.4 0.0 0.087 13.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.16 AET40048.1 - 0.049 12.7 0.1 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AET40048.1 - 0.054 13.0 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AET40048.1 - 0.057 12.6 0.2 0.19 10.9 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 AET40048.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PP2C PF00481.16 AET40049.1 - 5.2e-73 245.5 0.2 8.7e-73 244.8 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Med2 PF11214.3 AET40050.1 - 5.5e-30 103.4 7.1 5.5e-30 103.4 4.9 2.2 2 0 0 2 2 2 1 Mediator complex subunit 2 DUF3232 PF11554.3 AET40050.1 - 0.0014 18.5 0.1 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3232) DUF3038 PF11237.3 AET40050.1 - 0.0098 15.7 1.0 0.018 14.8 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3038) Menin PF05053.8 AET40050.1 - 0.73 7.9 10.7 0.97 7.5 7.4 1.4 1 0 0 1 1 1 0 Menin DUF2098 PF09871.4 AET40050.1 - 6.5 6.7 8.0 0.51 10.3 1.9 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) ATP-synt_DE_N PF02823.11 AET40051.1 - 1.2e-18 66.6 0.5 1.9e-18 65.9 0.4 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Granin PF01271.12 AET40051.1 - 0.045 12.4 0.1 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) Rad21_Rec8_N PF04825.8 AET40052.1 - 1.1e-25 89.6 0.3 2.2e-25 88.7 0.2 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 AET40052.1 - 2.1e-06 26.7 0.0 4.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DRIM PF07539.7 AET40053.1 - 2.1e-46 156.8 3.6 3.9e-46 155.9 0.7 3.1 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT_EZ PF13513.1 AET40053.1 - 0.39 11.2 1.3 41 4.8 0.1 4.7 5 0 0 5 5 5 0 HEAT-like repeat HMG_box PF00505.14 AET40054.1 - 1.7e-14 53.8 2.7 3.1e-14 52.9 1.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AET40054.1 - 3.3e-13 49.7 1.4 7e-13 48.7 1.0 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 AET40054.1 - 0.027 14.2 0.6 0.048 13.4 0.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CRA PF06589.6 AET40054.1 - 0.12 11.7 0.5 0.22 10.8 0.3 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Mak16 PF04874.9 AET40054.1 - 5.3 7.1 13.0 0.82 9.7 5.9 2.0 2 0 0 2 2 2 0 Mak16 protein C-terminal region DUF1168 PF06658.7 AET40054.1 - 7 6.1 10.6 0.42 10.1 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF155 PF02582.9 AET40055.1 - 4.1e-61 205.9 2.0 6.2e-61 205.3 1.4 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 AET40055.1 - 0.022 14.9 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Histone PF00125.19 AET40056.1 - 3.5e-26 91.1 0.0 4.8e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AET40056.1 - 4.1e-06 26.7 0.0 6.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AET40057.1 - 2.1e-22 79.0 0.3 3.1e-22 78.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AET40057.1 - 3.6e-06 26.9 0.6 6.9e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 AET40057.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 AET40057.1 - 0.1 12.0 0.2 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF77 PF01910.12 AET40058.1 - 8.8e-28 95.8 0.0 1e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 HTH_21 PF13276.1 AET40058.1 - 0.022 14.7 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 HTH-like domain FYRC PF05965.9 AET40058.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 F/Y rich C-terminus DUF2102 PF09875.4 AET40058.1 - 0.068 12.6 0.0 0.1 12.0 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Trehalase PF01204.13 AET40059.1 - 5.8e-185 615.7 0.0 6.9e-185 615.5 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 AET40059.1 - 5.1e-17 60.8 0.4 9.4e-17 60.0 0.3 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ran_BP1 PF00638.13 AET40060.1 - 9.8e-53 177.3 0.5 1.4e-52 176.9 0.3 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 AET40060.1 - 5.8e-05 22.7 0.3 0.0015 18.2 0.2 2.2 1 1 0 1 1 1 1 WH1 domain BRAP2 PF07576.7 AET40060.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 Adhes-Ig_like PF09085.5 AET40060.1 - 0.14 12.0 0.1 1.4 8.7 0.0 2.5 2 2 1 3 3 3 0 Adhesion molecule, immunoglobulin-like Prenyltransf PF01255.14 AET40061.1 - 5.8e-77 257.7 0.0 7.2e-77 257.4 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase polyprenyl_synt PF00348.12 AET40062.1 - 1.2e-53 181.5 0.1 2e-46 157.9 0.0 3.0 2 1 0 2 2 2 2 Polyprenyl synthetase Mannosyl_trans2 PF04188.8 AET40063.1 - 9.2e-63 212.6 52.4 1.8e-60 205.1 36.3 2.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF165 PF02592.10 AET40063.1 - 0.00012 22.2 4.4 0.036 14.2 0.2 2.9 2 1 0 2 2 2 2 Uncharacterized ACR, YhhQ family COG1738 RCR PF12273.3 AET40064.1 - 3.2e-33 115.0 2.7 3.2e-33 115.0 1.9 1.8 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Aldedh PF00171.17 AET40065.1 - 9e-156 518.7 0.1 1e-155 518.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 AET40065.1 - 0.03 13.5 0.1 0.1 11.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) SelA PF03841.8 AET40065.1 - 0.067 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Rad51 PF08423.6 AET40066.1 - 6.5e-28 97.3 0.0 5.9e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 AET40066.1 - 4e-10 39.4 0.0 7.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 AET40066.1 - 0.00027 20.0 0.6 0.0013 17.8 0.4 1.9 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AET40066.1 - 0.0013 17.9 0.3 0.0048 16.0 0.2 2.0 1 1 0 1 1 1 1 KaiC CobU PF02283.11 AET40066.1 - 0.0029 17.0 0.1 0.03 13.7 0.0 2.3 2 0 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_22 PF13401.1 AET40066.1 - 0.042 13.9 0.1 0.13 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain Maf1 PF09174.5 AET40067.1 - 2.5e-46 157.7 17.4 5.2e-42 143.7 10.1 3.5 2 1 0 2 2 2 1 Maf1 regulator Med15 PF09606.5 AET40067.1 - 0.03 12.5 28.5 0.037 12.2 19.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2422 PF10337.4 AET40067.1 - 0.26 10.0 4.3 0.38 9.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) PAT1 PF09770.4 AET40067.1 - 0.37 8.9 25.4 0.48 8.5 17.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 AET40067.1 - 0.87 9.3 11.9 1.5 8.5 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4407 PF14362.1 AET40067.1 - 1.1 8.1 7.9 1.8 7.4 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BAF1_ABF1 PF04684.8 AET40067.1 - 5.4 5.7 20.8 0.39 9.5 11.0 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Tcp11 PF05794.8 AET40068.1 - 1.4e-121 406.2 6.2 1.4e-121 406.2 4.3 2.7 2 1 0 2 2 2 1 T-complex protein 11 Histone PF00125.19 AET40069.1 - 2.5e-14 53.1 0.1 3e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 AET40069.1 - 5.4e-05 23.0 0.2 7.9e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 AET40069.1 - 6.1e-05 23.1 0.1 8.8e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AET40069.1 - 9.4e-05 22.4 0.1 0.00017 21.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 AET40069.1 - 0.0018 17.5 0.0 0.0019 17.5 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 AET40069.1 - 0.0041 16.8 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 AET40069.1 - 0.033 14.4 0.2 0.057 13.7 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 AET40069.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 AET40070.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AET40070.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AET40070.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AET40070.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated PRAI PF00697.17 AET40071.1 - 7.3e-54 182.3 0.0 9.5e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Pyrophosphatase PF00719.14 AET40072.1 - 3.4e-53 179.2 0.1 4.4e-53 178.9 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase zf-Apc11 PF12861.2 AET40073.1 - 1.6e-41 140.0 7.1 2.1e-41 139.6 4.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AET40073.1 - 4.4e-29 100.4 9.3 6.2e-29 99.9 6.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AET40073.1 - 1e-06 28.4 20.7 4.3e-06 26.4 13.2 2.7 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 AET40073.1 - 0.00018 21.1 13.3 0.0036 16.9 9.8 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 AET40073.1 - 0.00087 18.8 11.3 0.0028 17.1 0.3 3.0 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-HIT PF04438.11 AET40073.1 - 0.0083 15.7 3.0 0.0083 15.7 2.1 2.2 2 0 0 2 2 2 1 HIT zinc finger zf-HC5HC2H PF13771.1 AET40073.1 - 0.021 14.9 7.1 0.068 13.3 5.0 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.1 AET40073.1 - 0.028 14.4 15.6 0.29 11.1 10.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AET40073.1 - 0.034 13.8 13.6 1.6 8.4 9.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 AET40073.1 - 0.046 12.9 0.6 0.068 12.3 0.4 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 AET40073.1 - 0.055 13.3 4.4 0.055 13.3 3.0 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AET40073.1 - 0.18 11.5 19.6 0.28 10.8 11.9 2.5 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Opy2 PF09463.5 AET40073.1 - 0.23 11.5 12.2 0.13 12.3 4.8 2.3 2 0 0 2 2 2 0 Opy2 protein FANCL_C PF11793.3 AET40073.1 - 0.29 11.1 19.5 0.47 10.4 11.3 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 AET40073.1 - 0.51 10.3 8.7 0.23 11.4 4.0 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-Nse PF11789.3 AET40073.1 - 2.2 7.8 5.8 4.3 6.9 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 AET40073.1 - 3 7.9 15.6 4.2 7.4 9.2 2.4 2 1 0 2 2 2 0 RING-like domain RecR PF02132.10 AET40073.1 - 4.5 6.8 6.4 4 6.9 0.3 2.9 3 0 0 3 3 3 0 RecR protein Glutaredoxin PF00462.19 AET40074.1 - 5.6e-12 45.4 0.0 9.4e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin BetaGal_dom4_5 PF13364.1 AET40074.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Thioredoxin_7 PF13899.1 AET40074.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Mannosyl_trans3 PF11051.3 AET40075.1 - 1.3e-86 290.2 0.0 2.4e-86 289.4 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative NatB_MDM20 PF09797.4 AET40077.1 - 2.2e-61 207.5 8.5 4.1e-61 206.7 5.9 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF2611 PF11022.3 AET40078.1 - 1.7e-21 76.0 0.0 2.1e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Sugar_tr PF00083.19 AET40079.1 - 6.6e-115 384.2 30.9 7.6e-115 384.0 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET40079.1 - 4.2e-27 94.7 43.3 6.2e-21 74.4 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.17 AET40080.1 - 1.5e-127 426.2 1.3 1.8e-127 425.9 0.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 AET40080.1 - 0.0014 18.5 0.0 0.054 13.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1848 PF08902.6 AET40080.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1848) Calici_coat_C PF08435.6 AET40080.1 - 0.01 15.1 0.2 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal SIN1 PF05422.7 AET40081.1 - 1.1e-28 100.0 4.0 1.1e-27 96.7 2.8 2.4 1 1 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 AET40081.1 - 0.031 14.2 0.3 0.36 10.7 0.1 2.5 2 0 0 2 2 2 0 GLUT4 regulating protein TUG RNase_T PF00929.19 AET40082.1 - 2.5e-27 96.1 0.1 8.7e-27 94.4 0.0 1.8 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 AET40082.1 - 2.6e-05 23.7 0.0 0.0001 21.8 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease RasGAP PF00616.14 AET40083.1 - 2.3e-37 128.5 2.6 3.3e-37 128.0 0.0 2.7 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase DUF3321 PF11968.3 AET40084.1 - 4.3e-79 265.1 0.2 5.6e-79 264.8 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 AET40084.1 - 0.0057 16.3 0.0 0.01 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DEAD PF00270.24 AET40085.1 - 2.8e-37 127.8 0.0 6e-37 126.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET40085.1 - 4.7e-23 80.8 0.0 1.8e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AET40085.1 - 0.062 13.4 0.7 0.34 11.0 0.5 2.4 1 1 0 1 1 1 0 AAA domain eRF1_2 PF03464.10 AET40086.1 - 3.5e-45 153.5 0.1 5.8e-45 152.8 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AET40086.1 - 1.2e-38 131.8 0.5 2.5e-38 130.8 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 AET40086.1 - 2e-28 98.5 0.1 3.5e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 ZZ PF00569.12 AET40087.1 - 2.4e-18 65.4 43.9 1.1e-06 28.0 3.7 6.3 5 1 1 6 6 6 3 Zinc finger, ZZ type ATG19_autophagy PF12744.2 AET40087.1 - 2.8e-11 43.1 0.3 1.2e-10 41.1 0.2 2.0 1 1 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding DUF221 PF02714.10 AET40088.1 - 1.3e-105 352.8 16.6 1.3e-105 352.8 11.5 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AET40088.1 - 1.2e-38 132.1 4.4 1.2e-38 132.1 3.0 2.3 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AET40088.1 - 1.7e-25 88.7 0.1 3.5e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 AET40088.1 - 3.1e-16 59.6 0.3 5.7e-16 58.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 AET40088.1 - 0.1 12.2 0.0 0.36 10.4 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMEM154 PF15102.1 AET40088.1 - 0.19 11.4 0.4 0.56 9.9 0.3 1.8 1 0 0 1 1 1 0 TMEM154 protein family Cytochrom_B558a PF05038.8 AET40088.1 - 1.8 8.1 4.1 0.96 9.0 0.2 2.3 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Gp_dh_C PF02800.15 AET40089.1 - 2.9e-74 247.7 0.0 4.9e-74 247.0 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 AET40089.1 - 3.9e-59 198.9 0.5 1.1e-58 197.5 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 AET40089.1 - 0.0018 18.1 0.2 0.0053 16.6 0.1 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_N PF08240.7 AET40090.1 - 3.6e-30 103.9 0.1 7.6e-30 102.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AET40090.1 - 1.5e-29 102.1 0.8 2.1e-29 101.6 0.6 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AET40090.1 - 3.3e-05 24.7 0.9 5.1e-05 24.1 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ribosomal_S9 PF00380.14 AET40091.1 - 1.9e-39 134.6 0.2 2.9e-39 134.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CENP-S PF15630.1 AET40092.1 - 1.5e-25 89.1 0.0 2e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 AET40092.1 - 0.00017 20.9 0.1 0.00025 20.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 AET40092.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.11 AET40092.1 - 0.096 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 AET40092.1 - 0.11 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF3337 PF11816.3 AET40093.1 - 2.7e-54 184.8 1.4 1.3e-53 182.5 1.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 AET40093.1 - 9.8e-10 37.9 1.6 0.0037 17.0 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Rad60-SLD_2 PF13881.1 AET40093.1 - 0.027 14.3 0.1 0.067 13.0 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RNA_pol_Rpb5_N PF03871.9 AET40094.1 - 1.5e-33 115.0 0.2 2.8e-33 114.1 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 AET40094.1 - 2.3e-33 113.5 0.5 4.2e-33 112.7 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Sof1 PF04158.9 AET40094.1 - 0.034 14.1 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Sof1-like domain RibD_C PF01872.12 AET40095.1 - 3e-30 105.3 0.0 3.3e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Prp19_bind PF06991.6 AET40096.1 - 0.00063 19.1 17.8 0.00097 18.4 12.3 1.3 1 0 0 1 1 1 1 Splicing factor, Prp19-binding domain Pyrid_oxidase_2 PF13883.1 AET40097.1 - 3.2e-35 121.4 0.1 4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase VKOR PF07884.9 AET40097.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Gemin6 PF06372.7 AET40097.1 - 0.087 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Gemin6 protein Thioredoxin PF00085.15 AET40098.1 - 2.8e-13 49.4 0.1 1.3e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 AET40098.1 - 0.0011 19.0 0.1 0.0038 17.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thr_dehydrat_C PF00585.13 AET40098.1 - 0.0095 15.5 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 C-terminal regulatory domain of Threonine dehydratase Thioredoxin_2 PF13098.1 AET40098.1 - 0.047 13.8 0.2 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain Suc_Fer-like PF06999.7 AET40099.1 - 4.1e-52 177.5 0.0 5.4e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF1284 PF06935.6 AET40099.1 - 0.051 13.7 0.4 0.091 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) CRAL_TRIO PF00650.15 AET40100.1 - 8.1e-43 145.6 0.0 1.6e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AET40100.1 - 2.1e-14 53.3 0.1 6.4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AET40100.1 - 1.5e-09 37.9 0.1 6.4e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain tRNA-synt_1 PF00133.17 AET40102.1 - 6.3e-54 182.9 0.1 3.7e-32 111.1 0.2 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 AET40102.1 - 4.2e-40 137.0 0.0 9e-40 135.9 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 AET40102.1 - 7.6e-28 97.2 0.4 3.3e-22 78.7 0.0 4.5 4 1 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1d PF00750.14 AET40102.1 - 4.9e-05 22.3 0.0 9.1e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) Anticodon_1 PF08264.8 AET40102.1 - 0.00016 21.4 0.3 0.00016 21.4 0.2 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1c PF00749.16 AET40102.1 - 0.0032 16.1 0.3 1.4 7.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain DNA_ligase_ZBD PF03119.11 AET40102.1 - 0.0065 16.1 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.5 AET40102.1 - 0.14 12.1 1.1 0.67 9.9 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 AET40102.1 - 3 7.1 5.8 20 4.5 4.0 2.1 1 1 0 1 1 1 0 zinc-ribbon domain SMC_N PF02463.14 AET40103.1 - 1.3e-17 63.8 32.9 9e-17 61.0 22.8 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AET40103.1 - 1.6e-13 51.4 24.9 1.6e-13 51.4 17.2 5.1 2 2 1 3 3 3 1 AAA domain SMC_hinge PF06470.8 AET40103.1 - 9.1e-06 25.6 0.0 6.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AET40103.1 - 5.5e-05 23.2 18.5 0.055 13.4 0.1 4.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 AET40103.1 - 0.00013 21.3 0.0 0.00029 20.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 AET40103.1 - 0.00026 19.6 75.4 0.0049 15.4 11.6 5.3 3 2 2 5 5 5 3 AAA domain ABC_tran PF00005.22 AET40103.1 - 0.093 13.0 0.0 0.093 13.0 0.0 5.7 4 2 0 4 4 4 0 ABC transporter DUF869 PF05911.6 AET40103.1 - 0.44 8.7 62.4 0.003 15.8 15.7 2.7 2 1 0 2 2 2 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 AET40103.1 - 0.78 8.8 14.2 1.7 7.7 0.1 4.0 3 2 2 5 5 5 0 Reovirus sigma C capsid protein Adeno_PIX PF03955.9 AET40103.1 - 5.1 7.6 0.0 5.1 7.6 0.0 6.1 4 2 1 6 6 6 0 Adenovirus hexon-associated protein (IX) Uso1_p115_head PF04869.9 AET40104.1 - 1.3e-103 346.0 1.9 1.3e-103 346.0 1.3 2.4 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 AET40104.1 - 7.6e-12 45.3 18.6 7.6e-12 45.3 12.9 6.6 1 1 3 6 6 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region IncA PF04156.9 AET40104.1 - 5.2e-06 26.1 124.9 0.068 12.7 13.6 7.5 1 1 6 7 7 7 6 IncA protein BicD PF09730.4 AET40104.1 - 7.2e-05 21.3 22.6 7.2e-05 21.3 15.7 4.2 1 1 0 3 3 2 2 Microtubule-associated protein Bicaudal-D DUF3584 PF12128.3 AET40104.1 - 7.2e-05 20.3 44.8 7.2e-05 20.3 31.1 3.3 1 1 3 4 4 4 3 Protein of unknown function (DUF3584) Atg14 PF10186.4 AET40104.1 - 0.00042 19.3 21.2 0.00042 19.3 14.7 5.3 2 2 3 5 5 4 1 UV radiation resistance protein and autophagy-related subunit 14 Myosin_tail_1 PF01576.14 AET40104.1 - 0.00057 17.7 46.7 0.00057 17.7 32.3 3.9 1 1 2 3 3 3 2 Myosin tail GAS PF13851.1 AET40104.1 - 0.0033 16.6 121.1 0.0038 16.4 18.6 7.5 1 1 4 6 6 6 3 Growth-arrest specific micro-tubule binding Filament PF00038.16 AET40104.1 - 0.0045 16.4 100.8 0.033 13.6 11.4 5.5 1 1 4 5 5 5 3 Intermediate filament protein Cast PF10174.4 AET40104.1 - 0.021 12.8 110.1 0.12 10.3 19.5 3.2 1 1 2 3 3 3 0 RIM-binding protein of the cytomatrix active zone Reo_sigmaC PF04582.7 AET40104.1 - 0.16 11.1 64.6 0.24 10.5 1.1 6.6 1 1 6 7 7 7 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 AET40104.1 - 0.24 11.2 127.4 0.13 12.0 9.1 7.7 1 1 5 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_27 PF13514.1 AET40104.1 - 0.43 8.1 82.5 0.0031 15.2 9.5 3.1 1 1 2 3 3 3 0 AAA domain AAA_13 PF13166.1 AET40104.1 - 2.9 6.2 113.0 0.0029 16.1 14.9 4.3 1 1 3 4 4 4 0 AAA domain WEMBL PF05701.6 AET40104.1 - 3.7 5.9 113.8 0.12 10.7 22.4 3.5 1 1 2 3 3 3 0 Weak chloroplast movement under blue light Tropomyosin PF00261.15 AET40104.1 - 4.2 6.3 111.7 0.011 14.8 6.6 5.3 1 1 4 5 5 5 0 Tropomyosin Podoplanin PF05808.6 AET40105.1 - 0.091 12.3 1.5 0.18 11.3 1.0 1.4 1 0 0 1 1 1 0 Podoplanin Y_phosphatase2 PF03162.8 AET40106.1 - 2.2e-56 189.7 0.0 2.8e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AET40106.1 - 6.7e-06 26.4 0.0 4.1e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 AET40106.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DAD PF02109.11 AET40107.1 - 2.3e-38 130.7 3.6 2.9e-38 130.4 2.5 1.0 1 0 0 1 1 1 1 DAD family Cytochrom_B_C PF00032.12 AET40107.1 - 1.4 9.2 5.7 5.6 7.2 0.2 2.1 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Ras PF00071.17 AET40108.1 - 3.5e-55 185.7 0.2 4.3e-55 185.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET40108.1 - 3.2e-20 72.8 0.1 4.5e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET40108.1 - 1.2e-09 37.6 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AET40108.1 - 1.8e-05 24.2 0.1 7.6e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AET40108.1 - 0.0002 21.3 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AET40108.1 - 0.057 12.6 0.2 0.1 11.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 AET40108.1 - 0.12 11.7 0.2 0.24 10.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain ING PF12998.2 AET40109.1 - 3.4e-22 78.6 0.0 3.4e-22 78.6 0.0 2.0 3 0 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 AET40109.1 - 3.7e-09 36.1 8.9 7e-09 35.2 6.2 1.5 1 0 0 1 1 1 1 PHD-finger Serglycin PF04360.7 AET40109.1 - 0.0043 16.7 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 Serglycin zf-HC5HC2H PF13771.1 AET40109.1 - 0.0046 17.0 1.3 0.011 15.8 0.9 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.1 AET40109.1 - 0.023 14.0 2.6 0.051 12.8 1.8 1.6 1 0 0 1 1 1 0 PHD-finger Tom37_C PF11801.3 AET40109.1 - 0.083 12.7 2.9 1 9.2 0.0 2.3 2 1 0 2 2 2 0 Tom37 C-terminal domain Mito_carr PF00153.22 AET40110.1 - 4.6e-57 189.7 4.8 7.4e-20 70.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HsbA PF12296.3 AET40110.1 - 0.071 12.9 0.0 1.5 8.6 0.0 2.5 2 1 0 2 2 2 0 Hydrophobic surface binding protein A Glyco_transf_15 PF01793.11 AET40111.1 - 5.8e-144 479.0 17.8 7.3e-144 478.7 12.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_S7e PF01251.13 AET40112.1 - 1.9e-82 275.3 2.2 2.2e-82 275.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4265 PF14085.1 AET40112.1 - 0.081 12.6 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Rib_5-P_isom_A PF06026.9 AET40113.1 - 1.5e-56 190.4 0.0 1.9e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 AET40113.1 - 0.1 12.2 0.0 2.9 7.4 0.0 2.2 1 1 0 1 1 1 0 DeoR C terminal sensor domain Arf PF00025.16 AET40114.1 - 7.5e-71 236.9 0.1 8.4e-71 236.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AET40114.1 - 9.9e-14 51.0 0.0 1.1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AET40114.1 - 8.7e-13 47.7 0.7 2.2e-08 33.1 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 AET40114.1 - 2.5e-12 46.3 0.0 3.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AET40114.1 - 1.1e-10 41.0 0.0 1.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AET40114.1 - 1e-09 38.9 0.0 1.4e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AET40114.1 - 6.2e-06 26.1 0.0 8.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AMP-binding PF00501.23 AET40115.1 - 2.6e-34 118.3 0.0 1.6e-11 43.2 0.0 5.1 5 0 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.6 AET40115.1 - 3.6e-05 24.3 0.6 0.00038 21.0 0.1 2.7 2 0 0 2 2 2 1 DMAP1-binding Domain Mem_trans PF03547.13 AET40116.1 - 2.7e-53 180.6 5.4 3.2e-53 180.4 3.7 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF2183 PF09949.4 AET40117.1 - 1.7e-32 111.3 0.1 1.5e-31 108.3 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2183) DUF148 PF02520.12 AET40117.1 - 0.02 14.7 0.1 0.42 10.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 zf-CCCH PF00642.19 AET40118.1 - 4.4e-05 23.0 0.3 4.4e-05 23.0 0.2 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Codanin-1_C PF15296.1 AET40118.1 - 1.1 9.1 5.4 0.66 9.8 1.6 2.1 2 0 0 2 2 2 0 Codanin-1 C-terminus PP2C PF00481.16 AET40119.1 - 1.6e-44 152.2 0.0 2.6e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Ras PF00071.17 AET40120.1 - 1.2e-59 200.2 0.0 1.5e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET40120.1 - 1.4e-20 73.9 0.0 2.3e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET40120.1 - 1.7e-17 63.2 0.0 1.9e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET40120.1 - 1.4e-09 37.4 0.0 1.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AET40120.1 - 1.6e-06 27.7 0.0 2.9e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AET40120.1 - 3.5e-05 23.7 0.0 5.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ion_trans PF00520.26 AET40121.1 - 0.0002 20.6 15.1 0.018 14.2 9.1 3.7 3 1 0 3 3 3 1 Ion transport protein DUF106 PF01956.11 AET40121.1 - 0.0014 18.1 0.9 0.37 10.3 0.2 2.8 2 1 0 2 2 2 2 Integral membrane protein DUF106 DivIC PF04977.10 AET40121.1 - 0.027 13.9 0.1 0.21 11.1 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator NST1 PF13945.1 AET40122.1 - 2.8e-06 27.5 13.2 2.8e-06 27.5 9.1 6.3 5 2 1 6 6 6 1 Salt tolerance down-regulator Ras PF00071.17 AET40123.1 - 8.3e-51 171.5 0.0 9.5e-51 171.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET40123.1 - 1.9e-14 54.2 0.0 2.8e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET40123.1 - 3.8e-09 36.0 0.0 5e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 AET40123.1 - 2.1e-05 24.0 0.1 0.042 13.3 0.0 2.4 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 AET40123.1 - 0.03 13.5 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit C2 PF00168.25 AET40124.1 - 2.8e-54 180.9 2.2 1.1e-19 70.0 0.0 4.5 4 0 0 4 4 4 4 C2 domain Snapin_Pallidin PF14712.1 AET40125.1 - 5.6e-05 23.3 3.6 6.7e-05 23.1 2.5 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Tmemb_cc2 PF10267.4 AET40125.1 - 0.0027 16.3 1.3 0.0027 16.3 0.9 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Med28 PF11594.3 AET40125.1 - 0.0064 16.7 1.5 0.008 16.4 1.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 28 EzrA PF06160.7 AET40125.1 - 0.01 14.0 1.5 0.012 13.7 1.0 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF964 PF06133.6 AET40125.1 - 0.013 15.5 0.6 0.016 15.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF964) COG2 PF06148.6 AET40125.1 - 0.055 13.3 2.4 0.071 12.9 1.7 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4164 PF13747.1 AET40125.1 - 0.14 12.3 2.5 0.16 12.0 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF904 PF06005.7 AET40125.1 - 0.4 10.9 6.4 1.5 9.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) OST3_OST6 PF04756.8 AET40126.1 - 2.4e-18 66.2 6.1 4.1e-18 65.4 4.3 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 AET40126.1 - 0.022 14.4 0.0 0.061 13.0 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin MKT1_C PF12246.3 AET40127.1 - 5.5e-63 212.2 1.7 8e-63 211.6 1.2 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 AET40127.1 - 7.1e-32 109.5 0.1 1.6e-31 108.4 0.1 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 AET40127.1 - 2.1e-17 63.2 0.0 8.8e-17 61.2 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 AET40127.1 - 2.3e-08 33.9 0.0 7.2e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 XPG I-region Cpn60_TCP1 PF00118.19 AET40128.1 - 4.5e-137 457.6 12.4 5.3e-137 457.3 8.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 AET40128.1 - 0.031 13.8 0.0 0.096 12.2 0.0 1.8 1 0 0 1 1 1 0 TNP1/EN/SPM transposase EF-hand_4 PF12763.2 AET40129.1 - 1.4e-50 169.3 1.9 8.8e-49 163.5 0.6 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 AET40129.1 - 3.6e-45 154.0 0.0 5.3e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 AET40129.1 - 0.025 13.8 0.8 0.075 12.3 0.6 1.9 1 0 0 1 1 1 0 EF hand Lzipper-MIP1 PF14389.1 AET40129.1 - 0.033 14.2 4.0 0.63 10.1 2.3 2.9 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 EF-hand_8 PF13833.1 AET40129.1 - 0.045 13.3 0.3 0.099 12.2 0.2 1.6 1 0 0 1 1 1 0 EF-hand domain pair IncA PF04156.9 AET40129.1 - 0.43 10.1 6.1 1.2 8.6 4.2 1.7 1 1 0 1 1 1 0 IncA protein Spc24 PF08286.6 AET40129.1 - 0.57 9.8 3.2 1.4 8.6 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ATG16 PF08614.6 AET40129.1 - 1 9.1 4.3 4.5 7.0 3.0 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) He_PIG PF05345.7 AET40130.1 - 8.7e-12 44.8 2.3 0.0072 16.3 0.0 5.8 5 0 0 5 5 5 3 Putative Ig domain TMEM154 PF15102.1 AET40130.1 - 5.2e-06 26.2 0.1 1.2e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family SKG6 PF08693.5 AET40130.1 - 0.0015 17.7 0.2 0.0042 16.3 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 AET40130.1 - 0.019 14.6 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 AET40130.1 - 0.18 12.1 0.0 0.51 10.7 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain 4HBT PF03061.17 AET40131.1 - 6.1e-08 32.6 0.4 0.0072 16.4 0.1 2.7 2 1 0 2 2 2 2 Thioesterase superfamily Mito_carr PF00153.22 AET40132.1 - 1.3e-59 197.9 2.9 7.2e-20 70.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 AET40132.1 - 9.9e-15 54.4 5.7 6.3e-10 39.0 0.4 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 AET40132.1 - 4.2e-12 44.4 5.2 0.0014 17.8 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 AET40132.1 - 5.3e-12 44.5 5.0 0.00019 21.0 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 AET40132.1 - 2.3e-05 23.5 3.3 0.017 14.4 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 AET40132.1 - 0.011 15.3 4.3 1.1 8.8 0.0 3.3 1 1 2 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.4 AET40132.1 - 0.021 14.8 0.1 0.05 13.6 0.1 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 AET40132.1 - 0.12 12.2 0.0 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain HORMA PF02301.13 AET40133.1 - 6.1e-17 61.7 0.0 7.4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 HORMA domain DNA_mis_repair PF01119.14 AET40134.1 - 1.3e-25 89.2 0.0 5.3e-25 87.1 0.0 2.1 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 AET40134.1 - 1.9e-22 79.4 0.0 4.3e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 AET40134.1 - 2.1e-16 59.8 0.1 6.2e-16 58.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AET40134.1 - 1.1e-09 38.0 0.0 2.8e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S13 PF00416.17 AET40135.1 - 9.6e-24 83.8 0.2 9.6e-24 83.8 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S13/S18 IMS_HHH PF11798.3 AET40135.1 - 0.0019 18.1 0.1 0.031 14.3 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif FbpA PF05833.6 AET40135.1 - 0.047 12.2 0.0 0.048 12.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) CheX PF13690.1 AET40135.1 - 0.055 13.3 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX EOS1 PF12326.3 AET40136.1 - 9e-70 233.0 8.1 1.4e-69 232.4 5.6 1.3 1 0 0 1 1 1 1 N-glycosylation protein PLD_C PF12357.3 AET40136.1 - 0.017 14.6 0.0 0.086 12.3 0.0 2.0 2 0 0 2 2 2 0 Phospholipase D C terminal Tropomyosin_1 PF12718.2 AET40137.1 - 7.1e-34 116.7 25.9 8.5e-34 116.4 17.9 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 AET40137.1 - 1.4e-06 27.5 22.5 8e-06 25.1 15.6 1.9 1 1 0 1 1 1 1 Tropomyosin MscS_porin PF12795.2 AET40137.1 - 1.8e-05 24.1 19.9 2e-05 24.0 13.8 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Mod_r PF07200.8 AET40137.1 - 1.9e-05 24.6 18.1 2.6e-05 24.2 12.5 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.4 AET40137.1 - 0.0001 22.1 4.6 0.0001 22.1 3.2 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 AET40137.1 - 0.00074 19.2 24.5 0.032 13.9 13.6 2.0 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.14 AET40137.1 - 0.0067 14.2 22.8 0.0091 13.7 15.8 1.1 1 0 0 1 1 1 1 Myosin tail Spectrin PF00435.16 AET40137.1 - 0.0081 16.4 17.5 0.24 11.7 8.1 2.1 1 1 1 2 2 2 1 Spectrin repeat DUF3287 PF11690.3 AET40137.1 - 0.012 15.7 2.4 0.012 15.7 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) TMF_DNA_bd PF12329.3 AET40137.1 - 0.013 15.3 30.0 0.024 14.4 5.5 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 AET40137.1 - 0.02 14.8 23.8 0.67 9.9 3.8 3.5 1 1 2 3 3 3 0 bZIP transcription factor DUF1664 PF07889.7 AET40137.1 - 0.02 14.6 10.5 0.03 14.1 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) T4SS PF07996.6 AET40137.1 - 0.02 14.7 5.6 0.32 10.8 1.2 2.1 1 1 0 2 2 2 0 Type IV secretion system proteins ADIP PF11559.3 AET40137.1 - 0.023 14.6 22.1 0.15 11.9 0.8 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding RraB PF06877.6 AET40137.1 - 0.029 15.0 5.0 0.074 13.7 3.4 1.7 1 1 1 2 2 2 0 Regulator of ribonuclease activity B Fzo_mitofusin PF04799.8 AET40137.1 - 0.038 13.3 13.6 0.25 10.7 3.0 2.1 1 1 1 2 2 2 0 fzo-like conserved region ATG16 PF08614.6 AET40137.1 - 0.042 13.6 23.3 0.03 14.1 9.7 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 AET40137.1 - 0.053 13.4 22.8 0.84 9.5 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 AET40137.1 - 0.054 13.0 25.2 0.073 12.6 17.3 1.3 1 1 0 1 1 1 0 IncA protein DUF4201 PF13870.1 AET40137.1 - 0.059 12.8 19.5 0.11 11.8 13.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) WXG100 PF06013.7 AET40137.1 - 0.063 13.2 8.3 2 8.4 2.8 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Sec2p PF06428.6 AET40137.1 - 0.063 13.1 23.5 0.33 10.8 10.6 2.9 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p GAS PF13851.1 AET40137.1 - 0.072 12.2 23.8 0.34 10.0 16.5 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding KLRAQ PF10205.4 AET40137.1 - 0.076 13.0 16.7 1 9.4 5.6 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.6 AET40137.1 - 0.077 12.8 15.8 1.3 8.9 0.0 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Prominin PF05478.6 AET40137.1 - 0.091 10.2 9.5 0.1 10.1 6.6 1.1 1 0 0 1 1 1 0 Prominin APG6 PF04111.7 AET40137.1 - 0.095 11.7 23.2 0.13 11.2 16.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Arfaptin PF06456.8 AET40137.1 - 0.1 11.9 10.0 0.26 10.6 2.0 2.3 1 1 1 2 2 2 0 Arfaptin-like domain Atg14 PF10186.4 AET40137.1 - 0.1 11.4 16.4 0.12 11.2 11.4 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rootletin PF15035.1 AET40137.1 - 0.11 12.4 22.2 0.38 10.7 5.5 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion PilM PF07419.7 AET40137.1 - 0.13 11.7 1.1 0.89 9.0 0.0 2.0 1 1 1 2 2 2 0 PilM HlyD PF00529.15 AET40137.1 - 0.13 11.5 11.0 0.15 11.3 7.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Lectin_N PF03954.9 AET40137.1 - 0.13 11.6 9.4 0.15 11.4 2.0 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain HCMV_UL139 PF12507.3 AET40137.1 - 0.13 12.3 4.2 0.23 11.6 0.5 2.1 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Prefoldin_2 PF01920.15 AET40137.1 - 0.14 11.9 24.6 1.2 8.9 3.1 3.1 1 1 1 2 2 2 0 Prefoldin subunit Snapin_Pallidin PF14712.1 AET40137.1 - 0.16 12.3 17.5 0.16 12.2 3.6 2.3 1 1 1 2 2 2 0 Snapin/Pallidin AAA_27 PF13514.1 AET40137.1 - 0.16 9.5 14.3 0.18 9.4 9.9 1.0 1 0 0 1 1 1 0 AAA domain HOOK PF05622.7 AET40137.1 - 0.18 9.5 16.5 0.2 9.4 11.4 1.1 1 0 0 1 1 1 0 HOOK protein Spc24 PF08286.6 AET40137.1 - 0.19 11.4 23.3 0.72 9.5 0.1 3.0 1 1 1 2 2 1 0 Spc24 subunit of Ndc80 DivIVA PF05103.8 AET40137.1 - 0.22 11.5 20.4 1.5 8.8 2.4 2.8 1 1 1 2 2 2 0 DivIVA protein TBPIP PF07106.8 AET40137.1 - 0.22 11.0 20.6 0.3 10.6 7.0 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MeMO_Hyd_G PF02964.11 AET40137.1 - 0.24 11.3 2.6 0.28 11.0 1.8 1.1 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain T2SM PF04612.7 AET40137.1 - 0.26 11.0 4.3 1.1 9.0 1.2 2.1 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein M FliD_C PF07195.7 AET40137.1 - 0.31 10.2 12.8 1.3 8.2 0.2 2.8 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Phage_GP20 PF06810.6 AET40137.1 - 0.34 10.3 21.9 0.5 9.7 8.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 AAA_13 PF13166.1 AET40137.1 - 0.36 9.2 17.1 0.55 8.6 11.9 1.3 1 1 0 1 1 1 0 AAA domain Ax_dynein_light PF10211.4 AET40137.1 - 0.37 10.6 20.1 0.78 9.5 0.6 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain IFT57 PF10498.4 AET40137.1 - 0.37 9.4 17.6 0.65 8.6 12.2 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.4 AET40137.1 - 0.4 10.8 16.7 1.2 9.2 4.6 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 AET40137.1 - 0.41 10.6 18.3 3.4 7.7 0.2 2.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ERM PF00769.14 AET40137.1 - 0.45 10.0 22.8 0.78 9.2 15.8 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF904 PF06005.7 AET40137.1 - 0.48 10.7 30.2 9.2 6.6 14.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Fib_alpha PF08702.5 AET40137.1 - 0.52 10.4 11.9 1.9 8.5 8.2 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 AET40137.1 - 0.53 10.0 13.2 2.1 8.1 2.6 2.4 1 1 1 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.6 AET40137.1 - 0.53 10.7 13.5 2.7 8.4 5.5 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KIP1 PF07765.7 AET40137.1 - 0.6 10.0 9.2 0.19 11.5 1.6 2.4 1 1 1 2 2 2 0 KIP1-like protein TroA PF01297.12 AET40137.1 - 0.64 9.2 3.5 0.78 8.9 2.5 1.3 1 1 0 1 1 1 0 Periplasmic solute binding protein family Mnd1 PF03962.10 AET40137.1 - 0.66 9.6 18.8 1.6 8.3 13.1 1.6 1 1 0 1 1 1 0 Mnd1 family Striatin PF08232.7 AET40137.1 - 0.67 10.2 17.4 1.8 8.8 0.2 2.1 1 1 1 2 2 2 0 Striatin family Jnk-SapK_ap_N PF09744.4 AET40137.1 - 0.68 9.9 20.8 0.86 9.5 14.4 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.3 AET40137.1 - 0.87 6.8 17.2 1 6.6 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.6 AET40137.1 - 0.94 7.9 17.2 1.2 7.5 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) EzrA PF06160.7 AET40137.1 - 0.94 7.5 18.3 1.4 6.9 12.7 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HemX PF04375.9 AET40137.1 - 1 7.8 11.5 1.5 7.2 7.8 1.5 1 1 0 1 1 1 0 HemX Exonuc_VII_L PF02601.10 AET40137.1 - 1.1 8.4 14.5 1.2 8.2 10.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_2 PF07716.10 AET40137.1 - 1.1 9.1 20.2 2.5 8.0 2.1 3.6 2 1 2 4 4 4 0 Basic region leucine zipper GrpE PF01025.14 AET40137.1 - 1.2 8.6 19.8 2.6e+03 -2.2 13.7 2.5 1 1 0 1 1 0 0 GrpE Sipho_Gp157 PF05565.6 AET40137.1 - 1.3 8.6 13.9 0.17 11.4 4.7 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 Reo_sigmaC PF04582.7 AET40137.1 - 1.3 8.1 3.7 1.8 7.6 2.6 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein FemAB PF02388.11 AET40137.1 - 1.3 7.6 14.2 0.79 8.3 8.2 1.6 1 1 1 2 2 2 0 FemAB family Syntaxin_2 PF14523.1 AET40137.1 - 1.3 9.0 11.7 2.1 8.4 8.1 1.4 1 0 0 1 1 1 0 Syntaxin-like protein HisKA_3 PF07730.8 AET40137.1 - 1.6 9.1 4.7 5.1 7.5 0.6 2.5 1 1 2 3 3 2 0 Histidine kinase Tweety PF04906.8 AET40137.1 - 1.6 7.0 5.8 1.4 7.2 3.1 1.5 1 1 0 1 1 1 0 Tweety DUF4559 PF15112.1 AET40137.1 - 1.7 7.7 15.7 2.3 7.2 10.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) DUF972 PF06156.8 AET40137.1 - 1.7 9.0 19.7 2e+02 2.3 13.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Nup54 PF13874.1 AET40137.1 - 1.8 8.2 14.0 3.2 7.4 1.4 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CCDC155 PF14662.1 AET40137.1 - 1.8 8.1 23.9 2.3 7.7 16.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DivIC PF04977.10 AET40137.1 - 1.9 8.0 21.8 11 5.5 1.9 3.4 1 1 2 3 3 3 0 Septum formation initiator Spc7 PF08317.6 AET40137.1 - 2 7.0 20.5 2.2 6.8 14.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CDC37_N PF03234.9 AET40137.1 - 2.2 8.5 16.3 2.9 8.1 11.3 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding LXG PF04740.7 AET40137.1 - 2.4 7.9 13.5 4 7.1 9.3 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily V_ATPase_I PF01496.14 AET40137.1 - 2.6 5.8 15.4 2.9 5.6 10.3 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Med4 PF10018.4 AET40137.1 - 2.8 7.3 19.4 0.47 9.8 4.2 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Uds1 PF15456.1 AET40137.1 - 2.8 7.9 16.4 7.7 6.5 10.3 2.2 1 1 1 2 2 2 0 Up-regulated During Septation MCRS_N PF13325.1 AET40137.1 - 2.8 7.4 14.3 6.7 6.1 9.9 1.6 1 1 0 1 1 1 0 N-terminal region of micro-spherule protein Tnp_P_element PF12017.3 AET40137.1 - 2.8 7.0 12.1 2.5 7.2 3.3 2.6 1 1 0 2 2 2 0 Transposase protein TPR_MLP1_2 PF07926.7 AET40137.1 - 2.8 7.6 23.5 5.8 6.6 11.0 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.8 AET40137.1 - 2.9 6.8 11.5 4.4 6.2 8.0 1.4 1 1 0 1 1 1 0 TMPIT-like protein CENP-K PF11802.3 AET40137.1 - 2.9 7.0 16.6 0.86 8.7 5.9 2.0 1 1 1 2 2 2 0 Centromere-associated protein K DUF3818 PF12825.2 AET40137.1 - 3 6.4 8.6 3.3 6.3 5.9 1.0 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) CorA PF01544.13 AET40137.1 - 3.3 6.6 9.1 3.9 6.4 6.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF342 PF03961.8 AET40137.1 - 3.4 5.9 18.3 2.5 6.4 5.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) GBP_C PF02841.9 AET40137.1 - 3.9 6.5 17.9 4.4 6.4 12.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Adeno_PIX PF03955.9 AET40137.1 - 3.9 8.0 11.1 24 5.4 0.2 2.9 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF2203 PF09969.4 AET40137.1 - 4 7.6 9.9 20 5.4 5.7 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) NTP_transf_5 PF14907.1 AET40137.1 - 4.3 6.6 6.5 22 4.2 0.0 2.6 1 1 1 3 3 3 0 Uncharacterised nucleotidyltransferase OmpH PF03938.9 AET40137.1 - 4.3 7.2 16.1 15 5.4 11.1 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RPW8 PF05659.6 AET40137.1 - 4.4 6.8 7.7 45 3.5 5.3 2.2 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 XhlA PF10779.4 AET40137.1 - 4.4 7.2 17.7 3.5 7.5 4.0 2.9 1 1 1 2 2 2 0 Haemolysin XhlA DUF3450 PF11932.3 AET40137.1 - 4.6 6.4 15.0 2.7 7.1 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DNA_topoisoIV PF00521.15 AET40137.1 - 5.1 5.8 12.0 5.8 5.6 8.3 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Fmp27_WPPW PF10359.4 AET40137.1 - 6.3 5.0 16.6 16 3.7 11.5 1.7 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cluap1 PF10234.4 AET40137.1 - 7.6 5.6 16.9 9 5.4 11.7 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.11 AET40137.1 - 8.2 4.4 14.1 49 1.9 9.7 2.0 1 1 0 1 1 1 0 Herpesvirus UL6 like Prp18 PF02840.10 AET40137.1 - 8.3 6.2 7.7 13 5.5 5.2 1.6 1 1 0 1 1 1 0 Prp18 domain DUF848 PF05852.6 AET40137.1 - 8.4 6.2 16.4 11 5.9 11.1 1.4 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4164 PF13747.1 AET40137.1 - 8.6 6.5 15.3 6.2 7.0 7.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF2802 PF10975.3 AET40137.1 - 8.9 6.1 9.8 2.1e+03 -1.5 6.8 3.2 1 1 0 1 1 0 0 Protein of unknown function (DUF2802) Cauli_AT PF03233.8 AET40137.1 - 9.5 5.8 10.3 1.4e+02 2.1 0.0 2.4 1 1 1 2 2 2 0 Aphid transmission protein DnaJ PF00226.26 AET40139.1 - 1.6e-22 78.9 0.8 2.9e-22 78.1 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AET40139.1 - 1.4e-17 63.3 0.1 2.8e-16 59.1 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AET40139.1 - 1.7e-09 37.6 16.6 3.7e-09 36.5 11.5 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 AET40139.1 - 5 6.8 6.2 3.4 7.3 0.3 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DegS PF05384.6 AET40140.1 - 0.0029 16.8 0.6 0.0074 15.5 0.4 1.7 1 0 0 1 1 1 1 Sensor protein DegS YtxH PF12732.2 AET40140.1 - 0.015 15.6 11.3 0.84 10.0 0.2 4.3 3 1 0 3 3 3 0 YtxH-like protein Apolipoprotein PF01442.13 AET40140.1 - 0.02 14.4 4.3 0.065 12.7 3.0 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 AET40140.1 - 0.12 12.8 9.3 1 9.7 1.5 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Sec5 PF15469.1 AET40140.1 - 0.95 9.1 9.9 0.17 11.5 3.5 2.0 2 1 0 2 2 2 0 Exocyst complex component Sec5 Rotamase PF00639.16 AET40140.1 - 5 7.9 6.8 2.3 9.0 0.4 3.1 1 1 1 2 2 2 0 PPIC-type PPIASE domain DUF1752 PF08550.5 AET40141.1 - 1.5e-11 43.6 0.4 4.5e-11 42.1 0.3 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Brix PF04427.13 AET40142.1 - 2.9e-47 160.7 0.8 3.9e-47 160.4 0.5 1.1 1 0 0 1 1 1 1 Brix domain Kri1 PF05178.7 AET40142.1 - 0.067 13.4 1.1 0.1 12.8 0.7 1.2 1 0 0 1 1 1 0 KRI1-like family Synapsin PF02078.11 AET40142.1 - 0.1 12.7 0.0 14 5.8 0.0 2.3 2 0 0 2 2 2 0 Synapsin, N-terminal domain tRNA-synt_2 PF00152.15 AET40144.1 - 9.2e-72 241.6 0.0 1.2e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 AET40144.1 - 5.3e-07 29.0 0.2 9.8e-05 21.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 AET40144.1 - 2.6e-06 27.1 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 AET40144.1 - 0.027 14.0 0.0 9.2 5.8 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) NatB_MDM20 PF09797.4 AET40144.1 - 0.062 12.0 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit RNase_HII PF01351.13 AET40145.1 - 9.7e-63 211.4 0.0 1.2e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Gcw_chp PF09694.5 AET40145.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (Gcw_chp) 2-oxoacid_dh PF00198.18 AET40146.1 - 1.2e-75 253.7 0.1 1.5e-75 253.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AET40146.1 - 4.5e-17 61.4 0.1 9.4e-17 60.4 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AET40146.1 - 2.7e-16 58.9 0.5 2.7e-16 58.9 0.3 3.3 3 0 0 3 3 3 1 e3 binding domain Tom7 PF08038.7 AET40147.1 - 1.5e-18 65.9 0.0 1.9e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 AET40148.1 - 3.7e-58 193.2 1.6 2.6e-21 75.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L13 PF00572.13 AET40149.1 - 3.9e-26 91.5 0.6 5.3e-26 91.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 Fork_head PF00250.13 AET40151.1 - 4.6e-36 122.7 1.0 1e-35 121.6 0.1 2.0 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 AET40151.1 - 2.6e-12 46.6 0.6 8.1e-12 45.0 0.1 2.2 2 0 0 2 2 2 1 FHA domain Linker_histone PF00538.14 AET40151.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family Fungal_trans PF04082.13 AET40152.1 - 3.1e-26 91.8 2.7 3.2e-26 91.7 0.7 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET40152.1 - 8e-11 41.6 12.3 1.6e-10 40.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hid1 PF12722.2 AET40153.1 - 0.23 9.1 5.9 0.3 8.7 4.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SUN PF03856.8 AET40154.1 - 6.2e-101 336.8 9.6 6.2e-101 336.8 6.6 1.6 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) DUF605 PF04652.11 AET40154.1 - 1 8.6 30.0 1.5 8.1 20.8 1.2 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 AET40155.1 - 4.9e-28 98.1 0.1 6.1e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AET40155.1 - 2.5e-11 43.8 0.0 3.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AET40155.1 - 7.5e-11 42.0 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AET40155.1 - 5.8e-06 25.9 0.2 1.6e-05 24.4 0.1 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 AET40155.1 - 0.00013 21.2 0.0 0.0022 17.1 0.0 2.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 AET40155.1 - 0.00051 20.0 0.0 0.0016 18.4 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Transket_pyr PF02779.19 AET40156.1 - 2.8e-63 212.6 0.0 4.4e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 AET40156.1 - 1.2e-54 185.0 0.0 1.6e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Ribosomal_L6 PF00347.18 AET40157.1 - 2.8e-29 101.4 9.4 3.7e-15 56.1 2.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.11 AET40157.1 - 0.019 14.1 0.2 0.054 12.7 0.0 1.8 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) YbbR PF07949.7 AET40157.1 - 0.089 12.9 2.6 0.71 10.0 0.1 2.9 1 1 2 3 3 3 0 YbbR-like protein SNF2_N PF00176.18 AET40158.1 - 1.5e-85 286.6 0.6 1.5e-85 286.6 0.4 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AET40158.1 - 7.4e-21 73.8 0.2 1.6e-17 63.1 0.0 3.5 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Bromodomain PF00439.20 AET40158.1 - 4.3e-18 65.0 0.7 1.3e-17 63.4 0.5 1.9 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 AET40158.1 - 3e-13 49.7 2.4 3e-13 49.7 1.6 5.2 5 1 1 6 6 6 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 AET40158.1 - 0.00016 21.3 10.3 0.00016 21.3 7.1 2.6 3 0 0 3 3 3 1 HSA QLQ PF08880.6 AET40158.1 - 0.023 14.1 0.3 0.1 12.0 0.0 2.3 2 0 0 2 2 2 0 QLQ Caudo_TAP PF02413.12 AET40159.1 - 0.25 11.5 1.9 0.53 10.4 1.3 1.5 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF1003 PF06210.6 AET40159.1 - 2.6 7.9 4.5 5.3 6.9 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) MMS19_N PF14500.1 AET40160.1 - 2.1e-88 296.0 15.8 1.3e-87 293.3 2.2 3.8 4 0 0 4 4 4 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 AET40160.1 - 2.5e-86 289.9 27.6 2.5e-86 289.9 19.1 3.0 1 1 1 2 2 2 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 AET40160.1 - 2.5e-06 27.6 0.1 0.099 12.9 0.0 5.5 5 2 2 7 7 7 2 HEAT repeats HEAT PF02985.17 AET40160.1 - 0.0087 16.0 0.7 9.7 6.5 0.1 5.1 5 0 0 5 5 5 1 HEAT repeat DUF2435 PF10363.4 AET40160.1 - 0.12 12.3 8.1 1.1 9.2 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 AET40160.1 - 0.24 11.9 10.4 4.1 8.0 0.1 6.0 5 1 2 7 7 7 0 HEAT-like repeat VHS PF00790.14 AET40160.1 - 2.7 7.6 8.4 3.3 7.3 0.0 4.4 6 0 0 6 6 6 0 VHS domain Aa_trans PF01490.13 AET40162.1 - 4.7e-94 315.1 40.3 5.5e-94 314.9 28.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 AET40162.1 - 2.7e-06 26.1 48.5 8.7e-06 24.5 33.7 1.6 1 1 0 1 1 1 1 Amino acid permease COX2-transmemb PF09125.5 AET40162.1 - 2.5 7.7 8.2 0.14 11.7 0.2 3.0 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane DNA_pol_B PF00136.16 AET40163.1 - 1.4e-114 383.5 4.4 1.4e-114 383.5 3.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 AET40163.1 - 5.1e-66 221.6 3.8 1.1e-65 220.4 2.7 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 AET40163.1 - 4.9e-42 143.9 0.0 9.8e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 AET40163.1 - 1.3e-17 63.3 2.8 4.4e-17 61.6 1.9 2.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal SPOUT_MTase PF02590.12 AET40163.1 - 0.035 13.8 0.2 0.22 11.2 0.0 2.4 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase zinc_ribbon_5 PF13719.1 AET40163.1 - 0.046 13.3 1.8 5.1 6.7 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AET40163.1 - 0.15 11.7 2.1 8.6 6.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain SNARE PF05739.14 AET40164.1 - 2.2e-15 56.0 7.1 2.2e-15 56.0 4.9 1.7 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 AET40164.1 - 8.8e-06 25.6 6.4 8.8e-06 25.6 4.5 3.4 2 2 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.16 AET40164.1 - 9.9e-05 21.8 3.5 9.9e-05 21.8 2.4 2.1 2 0 0 2 2 2 1 Synaptobrevin EMP70 PF02990.11 AET40164.1 - 0.091 11.2 0.9 0.11 10.9 0.6 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 DUF3708 PF12501.3 AET40164.1 - 0.11 12.3 0.4 0.24 11.2 0.3 1.6 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Cluap1 PF10234.4 AET40164.1 - 0.36 10.0 17.3 0.046 12.9 4.8 2.4 1 1 2 3 3 3 0 Clusterin-associated protein-1 Laminin_II PF06009.7 AET40164.1 - 0.54 10.0 13.5 0.043 13.5 4.5 2.4 2 1 1 3 3 3 0 Laminin Domain II DUF1978 PF09321.5 AET40164.1 - 0.54 9.6 11.8 0.04 13.3 3.8 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1978) DUF912 PF06024.7 AET40164.1 - 0.7 9.9 6.7 0.11 12.5 0.7 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Baculo_PEP_C PF04513.7 AET40164.1 - 0.73 9.6 15.0 0.042 13.6 4.2 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SbcD_C PF12320.3 AET40164.1 - 2 8.5 6.0 10 6.2 2.3 3.1 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain bZIP_2 PF07716.10 AET40165.1 - 1.5e-05 24.7 0.8 1.5e-05 24.7 0.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 AET40165.1 - 0.00071 19.4 3.5 0.0015 18.4 2.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor PspB PF06667.7 AET40165.1 - 0.7 9.8 2.3 1.8 8.5 1.6 1.6 1 0 0 1 1 1 0 Phage shock protein B RGS PF00615.14 AET40166.1 - 3.1e-16 59.5 0.5 7.6e-16 58.2 0.3 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3091 PF11291.3 AET40166.1 - 0.052 13.5 0.6 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) HMGL-like PF00682.14 AET40167.1 - 4.2e-74 249.1 0.0 8.2e-74 248.2 0.0 1.5 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.5 AET40167.1 - 9.6e-26 90.1 1.6 1.4e-25 89.6 0.2 1.9 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain Syja_N PF02383.13 AET40168.1 - 1.2e-93 313.4 0.2 2e-93 312.6 0.1 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 AET40168.1 - 8.2e-25 88.1 0.0 1.4e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4551 PF15087.1 AET40168.1 - 0.25 9.6 5.2 0.4 8.9 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) YEATS PF03366.11 AET40170.1 - 2.9e-34 116.6 1.8 5.4e-34 115.7 1.3 1.4 1 0 0 1 1 1 1 YEATS family TPD52 PF04201.10 AET40170.1 - 0.062 13.0 0.2 0.098 12.3 0.2 1.2 1 0 0 1 1 1 0 Tumour protein D52 family Phage_Gp19 PF09355.5 AET40170.1 - 0.13 12.1 0.3 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 Microtub_assoc PF07989.6 AET40170.1 - 0.67 9.8 5.4 13 5.7 0.1 3.1 2 1 1 3 3 3 0 Microtubule associated Osmo_CC PF08946.5 AET40170.1 - 6.4 6.8 10.0 0.78 9.8 3.8 1.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil His_Phos_1 PF00300.17 AET40171.1 - 9.5e-24 84.2 0.0 3e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 AET40171.1 - 6.1e-17 60.7 0.0 1.1e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit Maf PF02545.9 AET40172.1 - 2e-43 147.7 0.1 2.5e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein ChlamPMP_M PF07548.6 AET40172.1 - 0.041 13.6 0.1 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain RRM_1 PF00076.17 AET40173.1 - 8.4e-18 63.7 0.3 3.2e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET40173.1 - 1.1e-12 47.7 0.1 4.8e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET40173.1 - 3.9e-10 39.4 0.1 7.6e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AET40173.1 - 0.039 13.7 0.0 0.21 11.3 0.0 2.3 1 1 0 1 1 1 0 Limkain b1 Cyt-b5 PF00173.23 AET40174.1 - 1.4e-22 79.2 0.1 2e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CLASP_N PF12348.3 AET40175.1 - 0.007 15.7 0.1 0.036 13.4 0.0 2.1 1 1 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 AET40175.1 - 0.022 14.8 0.0 78 3.7 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat DEAD PF00270.24 AET40176.1 - 5.4e-45 152.9 0.0 4e-44 150.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET40176.1 - 1.2e-28 98.7 0.0 4.1e-28 97.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET40176.1 - 0.00056 19.7 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 AET40176.1 - 0.18 10.1 0.0 2.4 6.4 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1253) RNA_pol_L_2 PF13656.1 AET40177.1 - 3.8e-31 106.3 0.0 5.4e-31 105.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AET40177.1 - 4.5e-14 51.3 0.0 6.1e-14 50.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-H2C2_2 PF13465.1 AET40178.1 - 7.9e-24 82.7 28.9 1e-09 38.1 0.7 4.5 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 AET40178.1 - 1.4e-21 75.4 33.9 1.1e-06 28.6 0.3 4.9 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET40178.1 - 1.2e-15 56.5 26.8 0.00023 21.2 0.3 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.7 AET40178.1 - 0.014 15.5 10.7 0.05 13.7 0.4 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 AET40178.1 - 0.21 11.5 15.2 3.8 7.5 0.2 4.2 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 AET40178.1 - 0.23 11.4 20.2 0.28 11.1 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 AET40178.1 - 0.51 10.6 17.6 11 6.3 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AET40178.1 - 0.6 10.3 19.8 1.8 8.8 0.4 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AET40178.1 - 1.4 9.1 16.8 15 5.8 2.2 3.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.4 AET40178.1 - 2.8 7.8 13.5 1.2 8.9 0.7 3.5 3 0 0 3 3 3 0 Zinc-finger domain zf-BED PF02892.10 AET40178.1 - 6.8 6.5 23.0 0.46 10.2 0.3 4.3 4 1 1 5 5 5 0 BED zinc finger TRAPP PF04051.11 AET40179.1 - 5.3e-35 120.1 1.0 1.5e-34 118.7 0.7 1.7 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component SH3_9 PF14604.1 AET40180.1 - 7.6e-28 95.8 0.3 4.8e-15 54.8 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 AET40180.1 - 1.8e-25 88.0 0.1 2.3e-12 46.1 0.0 2.7 3 0 0 3 3 3 2 SH3 domain FCH PF00611.18 AET40180.1 - 6.8e-23 80.6 2.6 1.9e-22 79.2 0.1 3.0 2 1 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 AET40180.1 - 2.3e-18 65.4 0.5 3e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 AET40180.1 - 0.015 15.4 0.3 0.53 10.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain DUF4463 PF14703.1 AET40180.1 - 0.016 15.7 0.9 0.016 15.7 0.6 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4463) DUF4239 PF14023.1 AET40180.1 - 0.02 14.2 4.0 0.21 10.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) OEP PF02321.13 AET40180.1 - 8 6.0 10.4 1.6 8.3 3.6 2.3 2 0 0 2 2 2 0 Outer membrane efflux protein DUF2417 PF10329.4 AET40181.1 - 2.2e-53 181.0 8.5 2.8e-53 180.6 5.9 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 AET40181.1 - 2.7e-15 56.8 0.0 5.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET40181.1 - 1.8e-11 44.0 0.0 3.8e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AET40181.1 - 5.9e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family HlyIII PF03006.15 AET40181.1 - 0.37 10.1 11.4 0.013 14.9 3.8 1.6 2 0 0 2 2 2 0 Haemolysin-III related FHA PF00498.21 AET40182.1 - 1.7e-15 56.8 0.0 3.8e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 AET40182.1 - 1.2e-06 28.2 13.3 1.9e-06 27.5 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AET40182.1 - 1.3e-05 25.2 5.2 2.4e-05 24.3 3.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AET40182.1 - 0.0036 17.0 5.6 0.0072 16.1 3.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 AET40182.1 - 0.006 16.2 14.4 0.01 15.4 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET40182.1 - 0.016 14.9 11.9 0.026 14.2 8.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Sec_GG PF07549.9 AET40182.1 - 0.063 12.5 0.6 0.13 11.5 0.4 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-RING-like PF08746.6 AET40182.1 - 0.098 12.6 8.9 0.2 11.6 6.2 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 AET40182.1 - 0.27 11.2 15.4 0.48 10.4 10.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Malate_synthase PF01274.17 AET40183.1 - 3.9e-216 718.0 0.0 4.8e-216 717.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 AET40183.1 - 0.0067 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RNA_pol_Rpb4 PF03874.11 AET40184.1 - 9.2e-30 103.0 1.4 1.1e-29 102.8 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Glyco_hydro_16 PF00722.16 AET40185.1 - 3.1e-45 153.7 2.6 3.1e-45 153.7 1.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Daxx PF03344.10 AET40185.1 - 0.33 9.3 4.1 0.42 9.0 2.8 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 AET40185.1 - 1.4 8.1 6.3 1.8 7.7 4.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 AET40185.1 - 2.1 6.1 8.9 2.7 5.7 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 AET40185.1 - 3.4 6.6 7.0 4.6 6.2 4.9 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 AET40185.1 - 3.8 5.4 6.9 5.4 4.9 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 AET40185.1 - 4.7 5.8 18.1 8.5 4.9 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HJURP_mid PF12346.3 AET40186.1 - 0.095 12.8 0.3 9.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat tRNA-synt_1g PF09334.6 AET40186.1 - 0.42 9.2 4.4 2.4 6.7 3.0 1.9 1 1 0 1 1 1 0 tRNA synthetases class I (M) Myb_DNA-bind_6 PF13921.1 AET40186.1 - 1.8 8.7 5.4 2 8.5 0.5 2.9 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF2205 PF10224.4 AET40186.1 - 3.2 7.3 7.8 7.3 6.2 0.3 3.3 2 2 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) Lectin_N PF03954.9 AET40187.1 - 0.055 12.8 2.2 0.26 10.6 0.7 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CENP-F_leu_zip PF10473.4 AET40187.1 - 0.2 11.4 3.1 0.14 12.0 0.5 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 AET40188.1 - 5.2e-275 914.1 12.3 5.9e-275 913.9 8.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Sec8_exocyst PF04048.9 AET40188.1 - 0.0038 16.8 0.8 0.44 10.1 0.1 3.3 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain BLOC1_2 PF10046.4 AET40188.1 - 0.041 14.0 0.2 4.2 7.5 0.0 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSP70 PF00012.15 AET40189.1 - 1.7e-45 155.0 0.3 4.1e-45 153.8 0.2 1.6 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AET40189.1 - 0.0021 16.6 0.1 0.033 12.7 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein ParcG PF10274.4 AET40189.1 - 0.041 13.7 0.4 0.18 11.6 0.0 2.3 3 0 0 3 3 3 0 Parkin co-regulated protein DIL PF01843.14 AET40190.1 - 1.1e-14 54.2 7.0 1.3e-07 31.4 0.1 3.1 3 0 0 3 3 3 2 DIL domain Ank_5 PF13857.1 AET40190.1 - 1.9e-06 27.9 0.5 4.4e-06 26.7 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PRMT5 PF05185.11 AET40191.1 - 1.4e-153 512.0 3.5 1.8e-153 511.7 2.4 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CKS PF01111.14 AET40192.1 - 3.6e-35 119.6 0.1 5.3e-35 119.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF2404 PF10296.4 AET40193.1 - 4.3e-31 106.9 0.2 1.1e-30 105.5 0.1 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 AET40193.1 - 2.1e-06 27.8 0.1 8.6e-06 25.8 0.1 2.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AET40193.1 - 0.01 16.1 0.4 0.065 13.4 0.0 2.7 3 1 0 3 3 3 1 Pleckstrin homology domain Cofilin_ADF PF00241.15 AET40195.1 - 9.9e-23 80.4 0.2 1.1e-13 51.2 0.2 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF2340 PF10209.4 AET40195.1 - 0.0019 18.3 0.1 0.0036 17.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) zf-RING_2 PF13639.1 AET40196.1 - 1.7e-12 46.9 26.4 8.8e-12 44.6 4.9 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 AET40196.1 - 1.7e-08 33.9 6.5 1.7e-08 33.9 4.5 3.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AET40196.1 - 6.9e-07 28.8 4.7 6.9e-07 28.8 3.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET40196.1 - 1.8e-06 27.8 7.2 1.8e-06 27.8 5.0 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AET40196.1 - 4.5e-06 26.4 2.7 4.5e-06 26.4 1.8 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AET40196.1 - 1e-05 25.5 6.0 1e-05 25.5 4.1 3.5 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AET40196.1 - 0.00071 19.2 4.6 0.00071 19.2 3.2 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AET40196.1 - 0.0009 19.0 4.7 0.0009 19.0 3.3 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AET40196.1 - 0.0011 18.6 5.1 0.0018 17.9 1.8 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-HC5HC2H PF13771.1 AET40196.1 - 0.0053 16.8 9.1 0.0053 16.8 6.3 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-RING_4 PF14570.1 AET40196.1 - 0.0079 15.7 5.0 0.0079 15.7 3.5 3.0 2 1 0 2 2 1 1 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 AET40196.1 - 0.3 10.8 0.1 0.3 10.8 0.0 4.5 4 1 0 4 4 3 0 Uncharacterised protein family UPF0547 FANCL_C PF11793.3 AET40196.1 - 1.3 8.9 26.9 0.57 10.1 4.9 3.2 3 1 0 3 3 2 0 FANCL C-terminal domain DZR PF12773.2 AET40196.1 - 3.6 7.4 17.4 1.2 8.9 4.6 3.2 2 2 0 2 2 2 0 Double zinc ribbon PHF5 PF03660.9 AET40197.1 - 3.7e-50 168.4 10.9 4.3e-50 168.2 7.6 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 AET40197.1 - 2.6 5.5 6.8 3 5.4 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Sec7 PF01369.15 AET40198.1 - 2.1e-36 125.3 7.9 4e-36 124.4 5.5 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 AET40198.1 - 0.00036 20.6 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 AET40198.1 - 0.037 14.2 0.1 0.29 11.3 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain ISN1 PF06437.6 AET40200.1 - 5.1e-168 559.0 0.0 5.9e-168 558.8 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Choline_transpo PF04515.7 AET40201.1 - 2.9e-102 341.8 20.1 2.9e-102 341.8 13.9 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter Xpo1 PF08389.7 AET40203.1 - 1.2e-26 93.4 8.3 1.5e-26 93.1 1.2 4.2 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 AET40203.1 - 5.3e-06 26.2 1.1 7e-05 22.6 0.3 3.3 2 1 1 3 3 3 1 Importin-beta N-terminal domain DUF285 PF03382.9 AET40203.1 - 0.029 13.9 0.5 0.11 12.1 0.4 2.0 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 LSM PF01423.17 AET40204.1 - 3.9e-13 48.7 0.0 4.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain TRAPPC9-Trs120 PF08626.6 AET40206.1 - 1.4e-235 784.5 20.4 2.2e-235 783.8 14.1 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Proteasome PF00227.21 AET40207.1 - 2.8e-47 160.4 0.1 3.6e-47 160.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 AET40207.1 - 1.5e-13 49.7 0.3 3.2e-13 48.7 0.2 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal MCH PF02289.11 AET40207.1 - 0.026 13.5 0.1 0.094 11.7 0.0 1.7 2 0 0 2 2 2 0 Cyclohydrolase (MCH) Formyl_trans_N PF00551.14 AET40208.1 - 4.4e-47 159.9 0.0 5.2e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase PINIT PF14324.1 AET40209.1 - 8.1e-33 113.5 0.7 1.5e-32 112.6 0.0 1.8 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.15 AET40209.1 - 2.9e-18 65.1 5.6 5.1e-18 64.3 3.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 AET40209.1 - 4.9e-13 48.2 0.0 8.6e-13 47.4 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 AET40209.1 - 3.2e-06 26.5 3.5 9.6e-06 25.0 2.4 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 AET40209.1 - 0.011 15.3 2.9 0.019 14.6 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET40209.1 - 0.035 14.1 4.0 0.065 13.2 2.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET40209.1 - 0.24 11.2 3.2 0.49 10.2 2.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 AET40209.1 - 0.29 11.0 4.9 0.55 10.1 3.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AET40209.1 - 0.63 9.7 3.7 1.3 8.7 2.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ICMT PF04140.9 AET40210.1 - 2.4e-30 104.5 0.3 2.4e-30 104.5 0.2 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 AET40210.1 - 4.5e-13 49.2 2.2 4.5e-13 49.2 1.5 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 AET40210.1 - 1.7e-06 27.4 2.2 2.5e-06 26.9 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 AET40210.1 - 0.01 15.2 0.6 0.018 14.4 0.4 1.4 1 0 0 1 1 1 0 NnrU protein DUF373 PF04123.8 AET40210.1 - 0.13 11.2 2.5 0.19 10.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) zf-HIT PF04438.11 AET40211.1 - 0.00072 19.1 12.2 0.0015 18.1 8.4 1.5 1 0 0 1 1 1 1 HIT zinc finger Carn_acyltransf PF00755.15 AET40212.1 - 2e-172 574.3 0.0 2.4e-172 574.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Thioredoxin PF00085.15 AET40213.1 - 9.7e-26 89.4 0.0 1.8e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DER1 PF04511.10 AET40213.1 - 1.1e-18 67.4 18.7 1.6e-18 66.9 12.9 1.2 1 0 0 1 1 1 1 Der1-like family Thioredoxin_8 PF13905.1 AET40213.1 - 7.1e-07 29.2 0.1 0.00014 21.8 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AET40213.1 - 1.1e-06 28.8 0.3 5.8e-05 23.2 0.1 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AET40213.1 - 0.00016 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 AET40213.1 - 0.0028 17.3 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 AET40213.1 - 0.02 14.4 0.0 0.047 13.2 0.0 1.7 1 0 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.1 AET40213.1 - 0.049 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DUF2955 PF11168.3 AET40213.1 - 3.9 7.1 14.4 0.82 9.3 1.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2955) EXS PF03124.9 AET40214.1 - 1.9e-68 231.0 29.3 2.3e-68 230.8 20.3 1.0 1 0 0 1 1 1 1 EXS family Ribosomal_L2_C PF03947.13 AET40215.1 - 9e-49 164.5 0.9 9e-49 164.5 0.6 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AET40215.1 - 2e-29 101.3 0.2 5.3e-29 100.0 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain ATP-synt_D PF01813.12 AET40216.1 - 7.6e-63 211.6 3.9 1.1e-62 211.1 2.7 1.2 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.1 AET40216.1 - 0.0068 16.3 1.1 0.016 15.1 0.1 2.1 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 Dict-STAT-coil PF09267.5 AET40216.1 - 0.16 12.1 2.0 1.2 9.3 0.3 2.1 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil TMPIT PF07851.8 AET40216.1 - 0.39 9.7 0.0 0.39 9.7 0.0 1.8 2 0 0 2 2 2 0 TMPIT-like protein AFG1_ATPase PF03969.11 AET40217.1 - 7.6e-78 261.8 0.0 3.8e-73 246.3 0.0 3.0 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 AET40217.1 - 4.6e-05 23.4 0.1 0.014 15.4 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AET40217.1 - 0.0006 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AET40217.1 - 0.0042 16.8 0.0 0.0077 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 AET40217.1 - 0.0055 16.8 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AET40217.1 - 0.018 14.7 0.0 0.048 13.3 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 AET40217.1 - 0.046 13.8 0.0 0.19 11.9 0.0 2.1 2 1 1 3 3 3 0 RNA helicase Mak10 PF04112.8 AET40218.1 - 9.7e-46 155.0 0.1 2.2e-45 153.8 0.1 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ribosomal_L11_N PF03946.9 AET40219.1 - 1.5e-17 62.7 0.6 4.8e-17 61.1 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AET40219.1 - 1.1e-10 41.5 1.1 1.5e-10 41.0 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain ACBP PF00887.14 AET40220.1 - 1e-25 89.1 0.1 1.7e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein MAP65_ASE1 PF03999.7 AET40221.1 - 5.8e-86 289.4 23.1 5.8e-86 289.4 16.0 2.2 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Spore_III_AB PF09548.5 AET40221.1 - 0.61 9.8 11.3 0.054 13.2 0.5 3.5 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) TA0956 PF11513.3 AET40221.1 - 1.1 9.2 7.7 0.65 10.0 0.2 3.2 2 1 1 3 3 3 0 Thermoplasma acidophilum protein TA0956 SGS PF05002.10 AET40222.1 - 4.1e-28 96.9 2.3 4.1e-28 96.9 1.6 2.8 3 0 0 3 3 3 1 SGS domain CS PF04969.11 AET40222.1 - 1.8e-10 41.2 0.2 6e-10 39.5 0.1 2.0 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 AET40222.1 - 7.6e-05 22.2 2.0 0.0036 16.9 0.4 2.4 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 AET40222.1 - 0.00049 20.4 0.2 0.0036 17.7 0.1 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 AET40222.1 - 0.00086 19.0 2.6 0.14 12.1 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 AET40222.1 - 0.0018 17.8 3.1 0.096 12.3 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 AET40222.1 - 0.041 14.3 1.2 1 9.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 AET40222.1 - 0.086 12.7 3.3 7.5 6.5 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AET40222.1 - 0.14 12.0 4.3 8 6.5 0.8 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 AET40222.1 - 0.26 11.6 3.4 0.58 10.5 0.6 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat dNK PF01712.14 AET40222.1 - 5.5 6.9 11.6 0.25 11.2 1.3 2.9 3 0 0 3 3 3 0 Deoxynucleoside kinase NOB1_Zn_bind PF08772.6 AET40223.1 - 1.3e-27 95.3 0.5 1.3e-27 95.3 0.3 1.9 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-FCS PF06467.9 AET40223.1 - 0.032 13.8 0.8 0.15 11.7 0.4 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-RING_3 PF14369.1 AET40223.1 - 0.15 12.0 0.5 0.38 10.7 0.4 1.7 1 0 0 1 1 1 0 zinc-finger AF1Q PF15017.1 AET40223.1 - 0.87 9.5 10.7 0.15 11.9 3.8 2.4 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator Flavoprotein PF02441.14 AET40224.1 - 3.2e-42 143.2 0.7 1.6e-41 141.0 0.5 2.1 1 1 0 1 1 1 1 Flavoprotein PPP4R2 PF09184.6 AET40224.1 - 0.011 15.3 27.5 0.023 14.2 19.1 1.5 1 0 0 1 1 1 0 PPP4R2 Hid1 PF12722.2 AET40224.1 - 0.12 10.0 5.0 0.23 9.1 3.5 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 AET40224.1 - 2.8 7.7 10.7 6.2 6.6 7.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 AET40224.1 - 4.3 6.6 32.6 8.5 5.6 22.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 AET40224.1 - 6.8 4.4 46.5 10 3.9 32.2 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 AET40224.1 - 7.1 4.2 10.5 10 3.6 7.3 1.2 1 0 0 1 1 1 0 Ycf1 CIAPIN1 PF05093.8 AET40225.1 - 4.3e-34 116.5 2.2 4.3e-34 116.5 1.6 1.9 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-CSL PF05207.8 AET40225.1 - 2.2 7.8 5.6 9.6 5.8 3.9 2.2 1 1 0 1 1 1 0 CSL zinc finger zf-AN1 PF01428.11 AET40226.1 - 6.7e-08 32.2 16.0 6.7e-08 32.2 11.1 2.5 2 1 0 2 2 1 1 AN1-like Zinc finger DUF605 PF04652.11 AET40226.1 - 0.016 14.6 5.5 0.021 14.2 3.8 1.1 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 AET40226.1 - 0.028 14.4 3.1 0.044 13.8 2.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_US9 PF06072.6 AET40226.1 - 0.16 11.7 0.2 0.16 11.7 0.1 1.9 2 0 0 2 2 1 0 Alphaherpesvirus tegument protein US9 PAT1 PF09770.4 AET40226.1 - 0.22 9.7 11.5 0.29 9.3 8.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF853 PF05872.7 AET40226.1 - 0.5 8.6 3.2 0.62 8.3 2.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3984 PF13136.1 AET40226.1 - 0.61 9.2 7.8 0.6 9.2 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) Macoilin PF09726.4 AET40226.1 - 0.77 7.9 9.2 0.79 7.9 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Ctr PF04145.10 AET40226.1 - 1.9 8.5 3.7 0.85 9.6 1.2 1.4 2 0 0 2 2 2 0 Ctr copper transporter family CbtA PF09490.5 AET40226.1 - 2.6 7.3 5.1 3.4 6.9 3.6 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Band_3_cyto PF07565.8 AET40226.1 - 2.8 7.3 6.7 3.3 7.1 4.6 1.2 1 1 0 1 1 1 0 Band 3 cytoplasmic domain Paf1 PF03985.8 AET40226.1 - 4.3 5.9 8.7 6.1 5.4 6.0 1.2 1 0 0 1 1 1 0 Paf1 UPF0560 PF10577.4 AET40226.1 - 5.7 5.0 13.0 8.6 4.4 9.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TP_methylase PF00590.15 AET40227.1 - 1.7e-38 132.4 0.1 2.4e-38 131.9 0.1 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 AET40227.1 - 0.002 18.3 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 AET40227.1 - 0.046 12.7 0.0 0.1 11.5 0.0 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Saccharop_dh PF03435.13 AET40227.1 - 0.14 11.1 0.0 0.55 9.1 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase TRAPP PF04051.11 AET40228.1 - 4.8e-36 123.5 0.0 6.1e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dsl1_N PF11988.3 AET40228.1 - 0.019 13.8 0.0 0.056 12.3 0.0 1.7 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal DUF111 PF01969.12 AET40228.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF111 Acyltransferase PF01553.16 AET40229.1 - 1.5e-08 34.1 0.0 8.5e-08 31.7 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Methyltransf_28 PF02636.12 AET40230.1 - 1.3e-08 34.5 0.1 1.8e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase XRN_N PF03159.13 AET40231.1 - 1.5e-105 351.8 0.0 4.4e-105 350.3 0.0 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Rubella_E2 PF05749.6 AET40231.1 - 0.091 11.9 4.2 0.15 11.2 2.9 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 DEAD PF00270.24 AET40233.1 - 5.5e-37 126.8 0.3 1.3e-35 122.4 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET40233.1 - 4.2e-26 90.6 0.0 8.2e-26 89.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 AET40233.1 - 0.00047 20.1 0.0 0.0088 16.0 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.10 AET40233.1 - 0.00073 19.4 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 AET40233.1 - 0.017 14.2 0.2 0.57 9.1 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 AET40233.1 - 0.062 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AET40233.1 - 0.12 12.4 0.2 0.53 10.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain Pmp3 PF01679.12 AET40234.1 - 3.4e-20 71.4 10.0 3.7e-20 71.3 7.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BTP PF05232.7 AET40234.1 - 0.26 11.0 3.4 0.32 10.7 2.4 1.1 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family DUF2304 PF10066.4 AET40234.1 - 0.61 9.9 4.6 0.66 9.8 3.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) CoxIIa PF08113.6 AET40234.1 - 0.79 9.4 4.6 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family NdhL PF10716.4 AET40234.1 - 1.5 8.6 5.7 2.2 8.1 3.9 1.4 1 1 0 1 1 1 0 NADH dehydrogenase transmembrane subunit DUF3099 PF11298.3 AET40234.1 - 6.8 6.5 6.2 1.1 9.0 1.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3099) TOMM6 PF15184.1 AET40235.1 - 0.16 11.3 0.3 0.17 11.1 0.2 1.3 1 1 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog CUE PF02845.11 AET40237.1 - 1.7e-05 24.2 0.0 2.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain Lactamase_B PF00753.22 AET40238.1 - 4.2e-24 85.2 0.0 5.8e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AET40238.1 - 0.0001 21.9 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 AET40238.1 - 0.066 12.4 0.1 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family E1-E2_ATPase PF00122.15 AET40239.1 - 1.4e-48 164.9 0.1 2.7e-48 163.9 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AET40239.1 - 4.4e-29 102.4 0.0 1.3e-28 100.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AET40239.1 - 3.1e-23 81.6 11.4 6e-12 45.5 0.5 2.5 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 AET40239.1 - 1e-09 38.8 0.0 2.6e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AET40239.1 - 1.1e-07 31.7 0.0 0.0024 17.4 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1205 PF06722.7 AET40239.1 - 0.16 12.2 1.3 0.25 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) DUF1677 PF07911.8 AET40239.1 - 0.19 11.9 2.9 9 6.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) Adhesin_Dr PF04619.7 AET40239.1 - 0.32 10.6 3.0 0.41 10.3 0.2 2.3 2 0 0 2 2 2 0 Dr-family adhesin CK_II_beta PF01214.13 AET40240.1 - 8.1e-71 237.3 0.0 1e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Hira PF07569.6 AET40241.1 - 2.4e-86 288.4 0.1 1.7e-85 285.7 0.0 2.1 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 AET40241.1 - 0.0084 15.9 0.1 1.1 9.2 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat tRNA-synt_1b PF00579.20 AET40242.1 - 4.4e-75 252.5 0.1 5.3e-75 252.2 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Sigma54_AID PF00309.15 AET40242.1 - 0.17 11.3 1.2 0.51 9.8 0.6 1.9 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) FAD_binding_6 PF00970.19 AET40243.1 - 3.4e-07 30.3 0.0 1.6e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain WD40 PF00400.27 AET40244.1 - 5.4e-55 181.4 33.3 6.4e-12 44.8 0.3 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 AET40244.1 - 0.00086 19.0 0.6 0.0052 16.5 0.0 2.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 AET40244.1 - 0.0064 14.3 2.0 0.019 12.7 0.5 2.0 1 1 1 2 2 2 1 IKI3 family CRT10 PF08728.5 AET40244.1 - 0.04 11.9 1.2 2.3 6.0 0.0 3.1 3 0 0 3 3 3 0 CRT10 Coatomer_WDAD PF04053.9 AET40244.1 - 0.13 11.0 4.4 0.2 10.3 1.2 2.5 2 1 0 2 2 2 0 Coatomer WD associated region SNARE PF05739.14 AET40245.1 - 6.6e-19 67.3 5.5 1.7e-18 66.0 3.8 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.1 AET40245.1 - 3.7e-17 62.2 6.2 3.7e-17 62.2 4.3 2.6 2 1 0 2 2 2 1 Syntaxin-like protein Spectrin PF00435.16 AET40245.1 - 0.1 12.8 8.5 0.33 11.2 5.6 2.0 2 0 0 2 2 2 0 Spectrin repeat Astro_capsid PF03115.9 AET40245.1 - 0.31 9.2 4.0 0.33 9.1 2.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor ATP-synt_S1 PF05827.7 AET40246.1 - 7.9e-47 159.9 0.0 9.7e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Pkinase PF00069.20 AET40248.1 - 7.1e-69 231.8 0.0 1.5e-68 230.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40248.1 - 8.9e-52 175.7 0.0 1.4e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40248.1 - 5.4e-07 28.8 0.1 7.2e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AET40248.1 - 0.011 15.4 0.0 4.8 6.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PQ-loop PF04193.9 AET40250.1 - 1.4e-30 104.5 14.1 2.6e-16 58.9 1.1 2.5 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 AET40250.1 - 0.06 13.2 3.1 0.98 9.3 0.1 3.4 2 2 0 3 3 3 0 Sugar efflux transporter for intercellular exchange CAP_N PF01213.14 AET40250.1 - 0.43 9.8 4.2 2.7 7.2 3.8 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Aldo_ket_red PF00248.16 AET40251.1 - 7.1e-51 172.6 0.0 8.6e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PX PF00787.19 AET40252.1 - 3.7e-13 49.2 0.1 5.2e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 PX domain Pyr_redox_2 PF07992.9 AET40253.1 - 5.4e-29 101.5 0.1 6.5e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AET40253.1 - 2.3e-16 59.9 0.1 1.4e-13 50.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AET40253.1 - 3.1e-10 40.4 0.0 2.9e-06 27.5 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AET40253.1 - 1.6e-05 24.0 0.5 0.77 8.5 0.2 4.0 3 1 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 AET40253.1 - 0.00012 22.2 0.0 0.083 13.1 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.15 AET40253.1 - 0.00021 21.4 0.2 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 AET40253.1 - 0.00032 19.8 0.0 0.006 15.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 AET40253.1 - 0.00076 18.4 1.9 0.76 8.5 0.1 2.9 3 1 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 AET40253.1 - 0.00089 19.2 0.1 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AET40253.1 - 0.001 18.0 0.0 1.6 7.5 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 AET40253.1 - 0.001 18.0 0.0 0.46 9.3 0.0 2.7 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 AET40253.1 - 0.024 13.7 0.0 5.4 5.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 AET40253.1 - 0.048 13.4 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glycos_transf_3 PF00591.16 AET40254.1 - 4e-74 249.2 0.0 5.3e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 AET40254.1 - 0.0028 17.2 0.2 0.0088 15.6 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Methyltransf_16 PF10294.4 AET40255.1 - 5.6e-22 78.0 0.0 1.1e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 AET40255.1 - 5.8e-08 32.4 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AET40255.1 - 7.5e-06 25.7 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AET40255.1 - 5e-05 22.7 0.0 8.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AET40255.1 - 0.00026 21.5 0.0 0.0012 19.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET40255.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 AET40255.1 - 0.017 15.5 0.0 0.066 13.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain GAS PF13851.1 AET40256.1 - 0.0021 17.3 23.4 0.0021 17.3 16.2 7.6 1 1 5 7 7 7 3 Growth-arrest specific micro-tubule binding FadA PF09403.5 AET40256.1 - 0.0028 17.6 12.7 0.0028 17.6 8.8 7.1 1 1 3 7 7 7 1 Adhesion protein FadA DUF2580 PF10824.3 AET40256.1 - 0.0052 17.1 0.6 0.18 12.1 0.2 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2580) M PF02370.11 AET40256.1 - 0.037 14.3 0.5 0.037 14.3 0.4 9.4 9 1 1 10 10 10 0 M protein repeat DUF2276 PF10040.4 AET40256.1 - 0.075 13.2 0.4 1 9.5 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2276) Reo_sigmaC PF04582.7 AET40256.1 - 0.74 8.9 24.6 0.0091 15.2 4.2 4.2 2 1 4 6 6 6 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 AET40256.1 - 2.3 8.5 30.5 5.1 7.4 5.5 7.9 3 2 3 6 6 6 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 AET40256.1 - 3.7 7.0 118.0 0.022 14.3 9.7 8.4 1 1 7 8 8 8 0 IncA protein PSI_PsaF PF02507.10 AET40256.1 - 6.9 6.1 14.3 3.7 7.0 0.1 3.6 3 1 0 3 3 3 0 Photosystem I reaction centre subunit III DUF2365 PF10157.4 AET40257.1 - 0.0075 16.1 0.3 0.025 14.4 0.1 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2365) Phage_tail_X PF05489.7 AET40257.1 - 0.077 12.4 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Phage Tail Protein X VHS PF00790.14 AET40258.1 - 5e-47 159.0 0.1 3.8e-46 156.2 0.0 2.2 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 AET40258.1 - 4.5e-20 72.0 0.0 8.6e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 AET40258.1 - 8.1e-14 51.4 2.2 2.5e-13 49.8 1.1 2.1 2 0 0 2 2 2 1 GAT domain IZUMO PF15005.1 AET40258.1 - 0.19 11.7 1.5 0.38 10.7 1.0 1.5 1 0 0 1 1 1 0 Izumo sperm-egg fusion Muted PF14942.1 AET40258.1 - 0.47 10.3 5.2 0.91 9.3 3.6 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein HSA PF07529.8 AET40259.1 - 1.3e-16 60.1 0.9 1.3e-16 60.1 0.6 2.7 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 AET40259.1 - 3.2e-09 36.7 0.6 1.9e-08 34.2 0.3 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AET40259.1 - 0.022 14.8 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain BCIP PF13862.1 AET40260.1 - 1e-52 178.5 1.1 1.4e-52 178.0 0.8 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF87 PF01935.12 AET40260.1 - 0.086 12.6 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 EMP24_GP25L PF01105.19 AET40261.1 - 1.4e-38 132.4 0.5 1.6e-38 132.2 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ThiF PF00899.16 AET40262.1 - 3.2e-41 140.3 0.1 8.2e-41 139.0 0.1 1.7 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 AET40262.1 - 1e-22 79.4 1.0 1.3e-22 79.1 0.1 1.6 2 0 0 2 2 2 1 MoeZ/MoeB domain Rhodanese PF00581.15 AET40262.1 - 3.5e-12 46.6 0.0 6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 AET40262.1 - 1.2e-05 25.3 0.3 0.00016 21.7 0.0 2.6 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Prp19 PF08606.6 AET40262.1 - 0.027 14.1 1.2 0.079 12.6 0.8 1.7 1 0 0 1 1 1 0 Prp19/Pso4-like Herpes_BLRF2 PF05812.7 AET40262.1 - 0.058 13.2 5.3 0.054 13.3 2.1 2.0 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein NAD_binding_7 PF13241.1 AET40262.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding APG6 PF04111.7 AET40262.1 - 2.9 6.8 7.3 1.9 7.4 2.8 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 WD40 PF00400.27 AET40263.1 - 0.027 14.3 6.5 0.26 11.2 0.6 4.8 5 1 0 5 5 5 0 WD domain, G-beta repeat Cys_Met_Meta_PP PF01053.15 AET40264.1 - 5.1e-63 212.6 0.0 1.5e-62 211.0 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AET40264.1 - 0.0025 16.6 0.0 0.0047 15.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AET40264.1 - 0.0088 15.0 0.0 0.013 14.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Rad60-SLD PF11976.3 AET40265.1 - 1.6e-21 75.7 1.9 1.4e-20 72.7 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RloB PF13707.1 AET40265.1 - 0.024 14.2 4.6 0.072 12.7 0.4 2.4 2 0 0 2 2 2 0 RloB-like protein DUF1777 PF08648.7 AET40265.1 - 0.05 13.3 15.1 0.095 12.4 10.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RNA_pol_Rpb1_5 PF04998.12 AET40266.1 - 3.7e-95 318.3 0.2 5.9e-95 317.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 AET40266.1 - 2.3e-84 283.5 0.0 3.6e-84 282.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AET40266.1 - 3.6e-70 235.2 0.0 7.6e-70 234.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AET40266.1 - 2.2e-39 134.7 0.0 6e-39 133.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AET40266.1 - 1.1e-30 105.5 0.0 2.7e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.11 AET40266.1 - 0.15 11.9 1.7 1.5 8.7 0.6 2.8 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DSS1_SEM1 PF05160.8 AET40267.1 - 9.8e-21 73.3 13.2 1.1e-20 73.1 9.1 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.24 AET40268.1 - 5.6e-41 139.8 0.0 1.1e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AET40268.1 - 2.1e-05 24.4 0.0 0.00018 21.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AET40268.1 - 2.8e-05 24.1 0.2 0.011 15.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 AET40268.1 - 6.4e-05 22.7 0.1 0.00039 20.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AET40268.1 - 0.0006 18.9 0.0 0.0012 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AET40268.1 - 0.00062 19.9 1.2 0.0076 16.3 0.2 2.6 2 1 0 2 2 1 1 AAA domain PhoH PF02562.11 AET40268.1 - 0.004 16.3 0.2 0.021 14.0 0.1 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 AET40268.1 - 0.0047 16.8 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 AET40268.1 - 0.0081 15.1 0.0 0.016 14.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 AET40268.1 - 0.0095 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 AET40268.1 - 0.0099 16.6 0.0 0.027 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AET40268.1 - 0.01 15.5 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 AET40268.1 - 0.012 14.8 0.2 0.032 13.3 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 AET40268.1 - 0.033 14.0 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 AET40268.1 - 0.034 14.2 0.8 0.14 12.3 0.5 2.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_25 PF13481.1 AET40268.1 - 0.04 13.3 0.6 0.34 10.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 AET40268.1 - 0.056 13.0 0.6 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 AET40268.1 - 0.066 12.7 0.1 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 AET40268.1 - 0.071 12.2 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 AET40268.1 - 0.17 10.9 1.3 0.38 9.8 0.0 2.1 3 0 0 3 3 3 0 KaiC DUF2730 PF10805.3 AET40268.1 - 0.4 10.4 2.9 2.4 7.9 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) ThylakoidFormat PF11264.3 AET40268.1 - 2.7 7.5 5.8 2 7.9 2.8 1.7 2 0 0 2 2 1 0 Thylakoid formation protein WD40 PF00400.27 AET40269.1 - 2.9e-36 122.0 6.7 2.2e-10 40.0 0.1 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 AET40269.1 - 3.2e-05 23.7 2.3 0.018 14.7 0.2 3.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A DUF846 PF05832.7 AET40270.1 - 4.8e-45 152.7 5.0 5.7e-45 152.5 3.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Serglycin PF04360.7 AET40270.1 - 0.0085 15.8 0.1 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Serglycin Methyltransf_8 PF05148.10 AET40271.1 - 1.3e-66 224.3 2.5 1.1e-64 218.1 0.4 2.4 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 AET40271.1 - 1.1e-07 32.2 0.3 4.4e-07 30.2 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET40271.1 - 4.6e-05 23.0 0.1 0.00026 20.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AET40271.1 - 0.0026 16.8 1.5 0.6 9.1 0.1 2.8 2 1 1 3 3 3 2 Putative methyltransferase Methyltransf_25 PF13649.1 AET40271.1 - 0.0083 16.4 0.0 0.037 14.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AET40271.1 - 0.025 14.2 0.0 0.025 14.2 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain MTS PF05175.9 AET40271.1 - 0.049 13.0 0.0 1.6 8.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase small domain NAF PF03822.9 AET40271.1 - 0.053 13.2 2.0 0.12 12.0 0.6 2.3 2 0 0 2 2 2 0 NAF domain AF1Q PF15017.1 AET40271.1 - 2.1 8.2 5.6 0.4 10.6 0.6 2.0 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Stn1 PF10451.4 AET40272.1 - 6.6e-46 156.2 0.7 1.2e-45 155.4 0.5 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Stn1_C PF12659.2 AET40272.1 - 2.4e-19 69.3 2.2 1.1e-18 67.2 0.9 2.3 2 0 0 2 2 2 1 Telomere capping C-terminal wHTH tRNA_anti-codon PF01336.20 AET40272.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DDE_1 PF03184.14 AET40273.1 - 3e-62 209.6 2.7 7.1e-62 208.3 1.9 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 AET40273.1 - 2.9e-12 46.2 0.2 9.5e-12 44.5 0.1 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Clathrin PF00637.15 AET40274.1 - 1.6e-28 99.0 11.7 2.7e-28 98.3 0.4 2.7 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_1 PF10366.4 AET40274.1 - 0.00026 20.9 3.1 0.0037 17.2 0.0 3.0 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.27 AET40274.1 - 0.00053 19.7 0.2 0.0021 17.8 0.1 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Tbf5 PF06331.7 AET40275.1 - 9.4e-29 99.0 0.0 1.1e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Sec34 PF04136.10 AET40276.1 - 2e-21 76.3 8.0 2e-21 76.3 5.5 3.9 4 0 0 4 4 4 1 Sec34-like family CR6_interact PF10147.4 AET40277.1 - 0.064 12.5 3.4 0.11 11.8 2.4 1.4 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 GvpL_GvpF PF06386.6 AET40277.1 - 0.081 12.5 0.9 0.1 12.1 0.6 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF UPF0160 PF03690.8 AET40278.1 - 3.6e-119 397.8 0.0 4.1e-119 397.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RhoGAP PF00620.22 AET40279.1 - 9.3e-40 135.7 0.1 4.2e-39 133.6 0.1 2.2 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 AET40279.1 - 2.8e-26 92.3 0.5 2.8e-26 92.3 0.3 2.9 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 AET40279.1 - 4.2e-18 65.3 2.4 2.2e-17 63.0 0.4 3.2 1 1 0 2 2 2 1 RasGEF N-terminal motif PH PF00169.24 AET40279.1 - 0.00053 20.1 0.0 0.0016 18.5 0.0 1.9 1 0 0 1 1 1 1 PH domain 60KD_IMP PF02096.15 AET40280.1 - 8.6e-35 120.1 1.6 8.6e-35 120.1 1.1 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein PET122 PF05476.6 AET40281.1 - 9.6e-52 175.8 5.1 1.1e-51 175.6 3.6 1.0 1 0 0 1 1 1 1 PET122 Aminotran_1_2 PF00155.16 AET40282.1 - 1.2e-19 70.5 0.0 1.6e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 AET40282.1 - 0.011 14.3 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase SWIM PF04434.12 AET40283.1 - 0.018 14.5 0.9 0.44 10.0 0.0 2.5 2 0 0 2 2 2 0 SWIM zinc finger UCH PF00443.24 AET40284.1 - 3e-55 187.2 1.1 9.1e-55 185.6 0.8 1.9 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EVI2A PF05399.6 AET40284.1 - 0.0046 16.2 1.4 0.012 14.9 1.0 1.7 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) HTH_45 PF14947.1 AET40285.1 - 2 8.2 7.0 1.8e+02 2.0 0.0 4.4 5 0 0 5 5 5 0 Winged helix-turn-helix KaiC PF06745.8 AET40286.1 - 4.3e-09 35.8 0.0 7.8e-09 34.9 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 AET40286.1 - 1.2e-05 24.7 0.0 6.2e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rad51 PF08423.6 AET40286.1 - 1.3e-05 24.2 0.0 2.9e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Rad51 RecA PF00154.16 AET40286.1 - 0.00036 19.7 0.1 0.0011 18.0 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 AET40286.1 - 0.0012 17.8 0.0 0.0035 16.2 0.0 1.8 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 AET40286.1 - 0.0036 17.4 0.0 0.0091 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AET40286.1 - 0.0038 16.8 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AET40286.1 - 0.0047 17.1 0.0 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AET40286.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase YjcZ PF13990.1 AET40286.1 - 0.0093 15.1 0.1 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 YjcZ-like protein AAA_24 PF13479.1 AET40286.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain nec1 PF10379.4 AET40286.1 - 0.038 13.2 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Virulence protein nec1 IstB_IS21 PF01695.12 AET40286.1 - 0.13 11.6 0.0 0.45 9.9 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Metallophos PF00149.23 AET40287.1 - 6e-40 136.7 0.3 7.4e-40 136.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AET40287.1 - 0.00024 20.9 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MscS_porin PF12795.2 AET40288.1 - 0.00033 20.0 7.2 0.00033 20.0 5.0 2.3 3 0 0 3 3 3 1 Mechanosensitive ion channel porin domain YqaJ PF09588.5 AET40288.1 - 0.0028 17.6 0.8 0.0062 16.5 0.6 1.6 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain Jnk-SapK_ap_N PF09744.4 AET40288.1 - 0.023 14.6 4.1 0.023 14.6 2.8 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Gon7 PF08738.5 AET40288.1 - 0.23 11.4 3.8 0.61 10.1 2.3 2.0 1 1 0 1 1 1 0 Gon7 family APG6 PF04111.7 AET40288.1 - 5.4 5.9 17.3 0.078 12.0 5.8 2.3 3 0 0 3 3 3 0 Autophagy protein Apg6 Laminin_I PF06008.9 AET40288.1 - 9.1 5.5 22.4 0.36 10.1 3.5 3.5 2 1 2 4 4 4 0 Laminin Domain I Phage_lysis PF03245.8 AET40288.1 - 9.5 6.2 11.8 19 5.2 2.9 2.5 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein TBP PF00352.16 AET40289.1 - 8.4e-70 230.1 0.1 4e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AET40289.1 - 0.00015 21.7 0.1 0.61 10.1 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) Cohesin_load PF10345.4 AET40290.1 - 5.3e-86 289.1 24.5 7.2e-86 288.7 17.0 1.1 1 0 0 1 1 1 1 Cohesin loading factor Glyco_transf_20 PF00982.16 AET40291.1 - 1.6e-148 495.1 0.1 2.1e-148 494.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 AET40291.1 - 8.5e-81 270.3 0.0 1.3e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase PAP2 PF01569.16 AET40293.1 - 5.8e-05 22.7 10.6 5.8e-05 22.7 7.4 3.0 2 2 0 2 2 2 1 PAP2 superfamily DUF4512 PF14975.1 AET40293.1 - 0.15 12.9 4.4 0.39 11.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4512) LSM PF01423.17 AET40294.1 - 3.2e-18 65.0 0.6 3.6e-18 64.8 0.4 1.0 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 AET40294.1 - 0.089 12.4 0.1 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain FTR1 PF03239.9 AET40295.1 - 1.4e-93 313.2 12.6 1.7e-93 312.9 8.7 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family DUF1218 PF06749.7 AET40295.1 - 7.9 7.0 10.6 2.7 8.5 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Acetyltransf_1 PF00583.19 AET40296.1 - 2.1e-08 34.0 0.0 3.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AET40296.1 - 2.9e-08 33.7 0.0 4.8e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AET40296.1 - 5.1e-06 26.3 0.0 0.0014 18.5 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AET40296.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AET40296.1 - 0.0028 17.6 0.0 0.0073 16.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AET40296.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 AET40296.1 - 0.026 14.6 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 AET40296.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein ABC_tran PF00005.22 AET40297.1 - 9e-22 77.8 0.0 5.3e-12 46.1 0.0 2.6 2 1 0 2 2 2 2 ABC transporter SbcCD_C PF13558.1 AET40297.1 - 6.3e-07 29.2 0.1 0.0002 21.2 0.0 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 AET40297.1 - 1.4e-06 28.5 4.7 0.039 13.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AET40297.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 AET40297.1 - 0.0028 17.7 0.0 0.36 10.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 AET40297.1 - 0.0047 16.1 0.4 2.1 7.4 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 AET40297.1 - 0.088 12.7 0.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.16 AET40298.1 - 8e-66 222.4 0.0 9.7e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AET40298.1 - 0.00057 18.7 0.0 0.00082 18.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AET40298.1 - 0.044 12.9 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase CSS-motif PF12792.2 AET40298.1 - 0.051 12.9 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 CSS motif domain associated with EAL OKR_DC_1 PF01276.15 AET40298.1 - 0.11 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Phosphodiest PF01663.17 AET40299.1 - 5.6e-14 52.2 1.1 6.8e-14 51.9 0.1 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 AET40299.1 - 0.00098 18.5 1.2 0.0018 17.6 0.8 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 AET40299.1 - 0.004 16.3 0.1 0.0072 15.5 0.1 1.4 1 0 0 1 1 1 1 Sulfatase ABC_tran PF00005.22 AET40300.1 - 3.3e-34 118.1 0.0 4.2e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 AET40300.1 - 2.4e-15 55.8 5.9 5.4e-15 54.6 4.1 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 AET40300.1 - 7.1e-14 52.4 12.5 0.00081 19.4 0.1 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 AET40300.1 - 2e-08 33.7 2.8 0.014 14.5 0.1 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 AET40300.1 - 2.7e-08 33.0 2.9 2.7e-08 33.0 2.0 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_15 PF13175.1 AET40300.1 - 4.3e-08 32.6 0.4 0.4 9.6 0.0 4.0 3 1 1 4 4 4 3 AAA ATPase domain Fer4_6 PF12837.2 AET40300.1 - 1.8e-06 27.5 11.2 3.8e-05 23.3 1.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain AAA PF00004.24 AET40300.1 - 4e-06 27.0 0.0 0.015 15.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AET40300.1 - 1.5e-05 25.0 0.0 0.0033 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 AET40300.1 - 2.1e-05 23.7 4.0 0.054 12.6 0.0 3.4 4 0 0 4 4 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 AET40300.1 - 3.5e-05 23.2 1.2 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AET40300.1 - 6e-05 23.8 0.2 0.38 11.5 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AET40300.1 - 8.2e-05 22.7 0.1 0.045 13.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 AET40300.1 - 0.00015 21.5 12.7 0.0003 20.5 8.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NB-ARC PF00931.17 AET40300.1 - 0.00017 20.5 0.1 0.043 12.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_7 PF12838.2 AET40300.1 - 0.00027 21.2 0.4 0.00027 21.2 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_18 PF13238.1 AET40300.1 - 0.00096 19.4 0.5 1.8 8.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 AET40300.1 - 0.00098 18.9 2.0 0.00098 18.9 1.4 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Miro PF08477.8 AET40300.1 - 0.00099 19.5 0.0 2 8.9 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_25 PF13481.1 AET40300.1 - 0.0013 18.1 0.1 0.77 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.1 AET40300.1 - 0.0033 17.1 1.3 0.0033 17.1 0.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.17 AET40300.1 - 0.0038 17.3 0.0 1.6 8.9 0.0 3.0 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.7 AET40300.1 - 0.0039 16.8 1.5 0.46 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 AET40300.1 - 0.0041 17.1 0.1 1.6 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_16 PF13484.1 AET40300.1 - 0.0057 17.3 0.1 0.0057 17.3 0.1 2.9 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain MobB PF03205.9 AET40300.1 - 0.0057 16.3 1.0 0.95 9.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_3 PF12798.2 AET40300.1 - 0.0058 17.1 4.2 0.0058 17.1 2.9 2.5 2 0 0 2 2 1 1 4Fe-4S binding domain VirE PF05272.6 AET40300.1 - 0.0059 16.0 0.0 0.86 9.0 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E AAA_33 PF13671.1 AET40300.1 - 0.0091 15.8 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AET40300.1 - 0.01 15.5 0.8 0.12 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 AET40300.1 - 0.01 15.4 0.2 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 AET40300.1 - 0.013 15.0 0.1 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 AET40300.1 - 0.013 15.3 0.1 6.3 6.7 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 AET40300.1 - 0.014 14.8 2.8 0.63 9.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_9 PF13187.1 AET40300.1 - 0.018 15.2 12.3 0.081 13.2 8.6 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Rad17 PF03215.10 AET40300.1 - 0.021 13.5 0.0 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 AET40300.1 - 0.024 14.5 0.1 14 5.5 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AET40300.1 - 0.041 13.3 0.1 3.9 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 AET40300.1 - 0.062 12.8 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 AET40300.1 - 0.093 11.6 0.0 3.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_8 PF13183.1 AET40300.1 - 0.15 12.0 8.4 0.13 12.2 1.0 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_23 PF13476.1 AET40300.1 - 0.19 12.0 0.1 0.19 12.0 0.0 3.1 2 1 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 AET40300.1 - 0.19 12.1 13.5 0.05 13.9 1.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain PduV-EutP PF10662.4 AET40300.1 - 1.4 8.3 4.6 0.65 9.4 0.1 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_15 PF13459.1 AET40300.1 - 8.6 7.0 10.3 0.13 12.8 0.8 2.7 3 0 0 3 3 1 0 4Fe-4S single cluster domain RRM_1 PF00076.17 AET40301.1 - 1.8e-84 277.3 3.1 8.5e-20 70.1 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET40301.1 - 8.6e-57 189.0 0.1 1.6e-15 56.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET40301.1 - 6.4e-50 166.8 0.0 4.2e-11 42.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 AET40301.1 - 2.6e-22 78.2 4.8 3.6e-22 77.8 0.5 2.8 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 AET40301.1 - 1.2e-06 28.3 10.3 0.46 10.3 0.0 5.0 3 1 2 5 5 5 3 RNA binding motif Nup35_RRM_2 PF14605.1 AET40301.1 - 0.017 14.8 0.1 11 5.8 0.0 3.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 AET40301.1 - 0.062 13.0 0.8 7.2 6.4 0.1 3.7 4 0 0 4 4 4 0 Limkain b1 DUF4523 PF15023.1 AET40301.1 - 0.072 12.6 0.0 0.7 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) K_channel_TID PF07941.6 AET40301.1 - 0.084 13.1 2.4 0.24 11.6 1.7 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain OB_RNB PF08206.6 AET40301.1 - 0.17 11.4 2.1 12 5.4 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain PNPase PF03726.9 AET40301.1 - 0.48 10.7 6.7 0.17 12.1 0.4 3.1 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain UQ_con PF00179.21 AET40302.1 - 4.5e-46 155.7 0.0 5.2e-46 155.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AET40302.1 - 4.5e-05 23.2 0.0 5.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AET40302.1 - 0.015 15.0 0.1 0.029 14.0 0.1 1.4 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 AET40302.1 - 0.04 13.7 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 RWD domain E1-E2_ATPase PF00122.15 AET40303.1 - 4.4e-15 55.3 0.0 4.4e-15 55.3 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 AET40303.1 - 4e-13 49.1 0.0 1.1e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AET40303.1 - 1.5e-12 48.0 0.0 4e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AET40303.1 - 8.4e-12 45.9 1.7 2.2e-09 38.0 1.2 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AET40303.1 - 0.0039 16.8 0.3 0.0039 16.8 0.2 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PolyA_pol PF01743.15 AET40304.1 - 2.4e-24 85.9 0.0 4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 AET40304.1 - 1.1e-07 31.2 0.0 2.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 AET40304.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative MPC PF03650.8 AET40305.1 - 8.9e-47 157.9 0.1 1e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ATP-grasp_2 PF08442.5 AET40306.1 - 4.7e-73 244.8 0.9 7.2e-73 244.2 0.6 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 AET40306.1 - 3.5e-25 88.3 0.3 1.5e-24 86.3 0.1 2.2 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 AET40306.1 - 7.4e-06 25.3 0.3 1.4e-05 24.4 0.2 1.5 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AET40306.1 - 0.0087 15.6 0.4 0.028 14.0 0.3 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 AET40306.1 - 0.044 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain SDA1 PF05285.7 AET40307.1 - 1.3e-94 317.1 28.6 1.3e-94 317.1 19.8 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 AET40307.1 - 5.3e-19 68.2 0.1 1.6e-18 66.7 0.1 1.9 1 0 0 1 1 1 1 NUC130/3NT domain TFIIB PF00382.14 AET40308.1 - 6.4e-55 182.8 0.8 1.1e-27 95.6 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 AET40308.1 - 3.2e-31 107.4 2.5 1.2e-30 105.5 0.0 2.5 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 AET40308.1 - 3.3e-12 45.5 3.1 5.8e-12 44.7 2.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 AET40308.1 - 7.4e-06 25.5 0.5 0.039 13.5 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 AET40308.1 - 0.026 13.7 1.5 0.048 12.8 1.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF3947 PF13135.1 AET40308.1 - 0.19 11.9 0.0 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Zn-ribbon_8 PF09723.5 AET40308.1 - 0.31 11.0 1.5 0.88 9.5 1.0 1.8 1 0 0 1 1 1 0 Zinc ribbon domain CPDase PF07823.6 AET40309.1 - 4.2e-64 215.6 0.0 4.8e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 AET40309.1 - 0.00056 19.6 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily Glucosamine_iso PF01182.15 AET40310.1 - 4.2e-48 163.7 0.0 5.1e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HSF_DNA-bind PF00447.12 AET40311.1 - 1e-24 86.6 0.0 1e-24 86.6 0.0 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding Peptidase_S49_N PF08496.5 AET40311.1 - 0.41 10.4 3.2 1 9.1 2.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Tim54 PF11711.3 AET40311.1 - 1.4 7.3 8.8 2.3 6.7 6.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3573 PF12097.3 AET40311.1 - 2.4 6.6 10.6 0.26 9.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) DUF4175 PF13779.1 AET40311.1 - 9 3.8 26.5 15 3.1 18.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RRM_1 PF00076.17 AET40312.1 - 9.2e-35 118.1 0.1 1.3e-14 53.5 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET40312.1 - 1.6e-22 79.2 0.0 5e-09 36.0 0.0 4.4 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET40312.1 - 8.1e-13 48.0 0.2 0.00024 20.9 0.0 4.1 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dna2 PF08696.6 AET40313.1 - 9.7e-63 211.2 1.9 1.9e-62 210.2 1.3 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 AET40313.1 - 8.8e-50 168.8 0.0 1.8e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AET40313.1 - 9.6e-39 133.3 2.5 2.1e-35 122.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.1 AET40313.1 - 5e-13 49.0 0.0 1.2e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AET40313.1 - 2e-08 33.8 0.0 7e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain PDDEXK_1 PF12705.2 AET40313.1 - 3.5e-07 29.8 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 AET40313.1 - 6.9e-06 25.7 0.3 0.73 9.3 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 AET40313.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Cas_Cas4 PF01930.12 AET40313.1 - 3e-05 23.9 1.0 0.00015 21.7 0.3 2.4 1 1 0 2 2 2 1 Domain of unknown function DUF83 SRP54 PF00448.17 AET40313.1 - 0.00027 20.4 0.1 0.00058 19.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 AET40313.1 - 0.00061 19.2 0.2 0.002 17.5 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 AET40313.1 - 0.0024 17.5 0.1 0.0066 16.1 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 AET40313.1 - 0.0033 16.3 0.0 0.0089 14.9 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.1 AET40313.1 - 0.0074 16.6 0.0 0.038 14.2 0.0 2.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 AET40313.1 - 0.01 14.8 0.0 0.029 13.3 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 AET40313.1 - 0.013 15.1 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 Helicase NTPase_1 PF03266.10 AET40313.1 - 0.021 14.5 0.8 0.25 11.0 0.2 2.8 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 AET40313.1 - 0.026 14.2 0.1 0.12 12.1 0.1 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AET40313.1 - 0.04 13.3 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 AET40313.1 - 0.048 12.4 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 AET40313.1 - 0.067 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 AET40313.1 - 0.069 12.4 0.0 0.069 12.4 0.0 3.1 3 1 0 3 3 2 0 UvrD/REP helicase N-terminal domain AAA_33 PF13671.1 AET40313.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 AET40313.1 - 0.43 10.3 4.0 0.25 11.1 0.1 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PalH PF08733.5 AET40314.1 - 3.5e-69 233.2 20.8 4.6e-69 232.8 14.4 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF2142 PF09913.4 AET40314.1 - 0.14 10.7 19.3 0.029 13.0 7.1 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2142) Abhydrolase_6 PF12697.2 AET40315.1 - 1.6e-30 106.6 0.0 4.5e-30 105.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET40315.1 - 9.6e-22 77.6 0.0 3.6e-17 62.6 0.0 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AET40315.1 - 1.6e-11 44.1 0.0 7.3e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 AET40315.1 - 2.5e-05 22.9 0.0 9.1e-05 21.0 0.0 1.9 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 AET40315.1 - 0.00047 19.9 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 AET40315.1 - 0.00051 19.6 0.0 0.0031 17.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 AET40315.1 - 0.0014 18.1 0.0 0.0036 16.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 AET40315.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.15 AET40315.1 - 0.0016 17.8 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 AET40315.1 - 0.0032 17.0 0.0 0.0096 15.5 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.16 AET40315.1 - 0.0047 16.1 0.0 0.042 13.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family PGAP1 PF07819.8 AET40315.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 AET40315.1 - 0.034 13.8 0.0 0.081 12.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Cellulase PF00150.13 AET40316.1 - 3.9e-13 49.2 4.2 3.9e-13 49.2 2.9 2.1 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) bZIP_1 PF00170.16 AET40318.1 - 6.7e-07 29.1 17.0 6.7e-06 25.9 11.8 2.2 1 1 0 1 1 1 1 bZIP transcription factor PAT1 PF09770.4 AET40318.1 - 0.14 10.4 17.7 0.17 10.0 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_2 PF07724.9 AET40319.1 - 1e-50 172.0 0.0 3.1e-48 163.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 AET40319.1 - 3.6e-26 90.8 2.0 7.4e-26 89.8 0.2 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 AET40319.1 - 3.8e-22 78.8 0.0 3.7e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AET40319.1 - 6.5e-17 61.5 0.2 1.4e-11 44.2 0.0 3.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AET40319.1 - 5.4e-14 52.6 0.9 0.00028 20.9 0.0 4.3 3 2 1 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 AET40319.1 - 4.3e-08 33.3 0.0 0.0022 18.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AET40319.1 - 2.1e-07 31.3 1.5 0.0046 17.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 AET40319.1 - 2.1e-07 30.5 0.1 2.7e-05 23.7 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 AET40319.1 - 2.7e-07 31.4 1.2 0.037 14.8 0.0 3.5 4 1 0 4 4 2 2 AAA domain Arch_ATPase PF01637.13 AET40319.1 - 6.1e-07 29.3 9.1 0.0034 17.1 0.3 4.8 3 3 2 5 5 3 1 Archaeal ATPase AAA_14 PF13173.1 AET40319.1 - 6.1e-07 29.3 0.0 0.046 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AET40319.1 - 6.7e-07 28.8 0.0 0.024 14.0 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein NACHT PF05729.7 AET40319.1 - 3e-05 23.7 0.0 0.058 13.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ABC_tran PF00005.22 AET40319.1 - 0.00015 22.0 1.1 0.31 11.3 0.0 3.5 3 0 0 3 3 3 1 ABC transporter DUF258 PF03193.11 AET40319.1 - 0.00021 20.5 0.0 0.036 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 AET40319.1 - 0.00022 21.2 0.0 0.38 10.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 AET40319.1 - 0.00025 20.7 0.0 0.31 10.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 AET40319.1 - 0.00035 20.7 0.1 0.84 9.8 0.0 3.2 2 1 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 AET40319.1 - 0.00038 20.1 0.0 0.89 9.3 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_29 PF13555.1 AET40319.1 - 0.00041 19.8 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 AET40319.1 - 0.00042 19.3 0.9 0.41 9.5 0.2 3.6 2 2 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 AET40319.1 - 0.00054 19.8 0.3 0.059 13.3 0.0 3.2 3 1 0 3 3 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 AET40319.1 - 0.00054 19.4 0.0 0.4 10.1 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 AET40319.1 - 0.00076 18.6 0.0 0.016 14.3 0.0 2.7 2 1 0 2 2 2 1 Zeta toxin UPF0079 PF02367.12 AET40319.1 - 0.0022 17.6 0.0 1.4 8.5 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 AET40319.1 - 0.0028 17.2 0.0 2.4 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AET40319.1 - 0.0036 16.4 0.1 0.77 8.8 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.4 AET40319.1 - 0.004 15.8 0.0 2.3 6.7 0.0 2.8 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 AET40319.1 - 0.0042 16.4 2.4 3.7 6.9 0.1 3.7 3 2 0 3 3 3 0 AAA domain SRP54 PF00448.17 AET40319.1 - 0.0051 16.2 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain T2SE PF00437.15 AET40319.1 - 0.0056 15.6 0.0 0.088 11.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 AET40319.1 - 0.0084 16.6 0.3 0.41 11.1 0.0 3.2 3 0 0 3 3 2 1 Miro-like protein AAA_33 PF13671.1 AET40319.1 - 0.0087 15.9 0.1 2 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 AET40319.1 - 0.0089 16.3 13.7 0.13 12.5 0.0 4.1 3 2 1 4 4 2 1 AAA domain ResIII PF04851.10 AET40319.1 - 0.012 15.4 4.0 4 7.2 0.0 3.8 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 AET40319.1 - 0.012 15.1 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PhoH PF02562.11 AET40319.1 - 0.015 14.5 0.0 1.6 7.9 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein DUF948 PF06103.6 AET40319.1 - 0.019 14.8 0.5 0.068 13.0 0.3 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_10 PF12846.2 AET40319.1 - 0.022 14.2 1.0 0.41 10.0 0.0 3.1 3 1 0 3 3 2 0 AAA-like domain DUF87 PF01935.12 AET40319.1 - 0.026 14.3 4.1 3.1 7.5 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_6 PF12774.2 AET40319.1 - 0.027 13.9 0.0 5 6.5 0.0 2.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_24 PF13479.1 AET40319.1 - 0.03 13.9 0.0 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 AET40319.1 - 0.03 13.9 0.1 0.65 9.6 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LacI PF00356.16 AET40319.1 - 0.034 13.7 0.0 6.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family AAA_21 PF13304.1 AET40319.1 - 0.036 14.0 4.3 8.3 6.2 0.0 4.2 3 2 1 5 5 5 0 AAA domain Torsin PF06309.6 AET40319.1 - 0.049 13.5 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Torsin V-SNARE PF05008.10 AET40319.1 - 0.19 11.9 5.4 0.25 11.5 1.7 2.7 3 0 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus TPR_11 PF13414.1 AET40320.1 - 2.6e-52 174.3 28.0 9.5e-15 54.0 0.0 6.2 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 AET40320.1 - 2.7e-42 140.6 25.5 3.6e-09 35.8 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 AET40320.1 - 6.9e-36 119.2 23.4 1.2e-07 31.0 0.1 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 AET40320.1 - 4.9e-22 77.6 19.2 2.3e-10 40.2 2.5 5.9 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 AET40320.1 - 6.6e-19 68.0 21.3 0.00041 20.9 0.9 6.6 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 AET40320.1 - 3e-18 64.1 23.0 1.2e-05 24.7 0.1 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 AET40320.1 - 1.2e-17 62.8 10.0 0.0042 17.5 0.0 8.8 6 3 3 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 AET40320.1 - 5e-16 58.8 20.3 0.002 18.4 1.9 7.1 4 3 2 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 AET40320.1 - 3.6e-11 41.9 21.8 0.0014 18.2 0.1 8.3 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 AET40320.1 - 1.1e-07 31.6 5.0 0.0018 18.0 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 AET40320.1 - 2.1e-07 30.6 12.8 0.16 12.2 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 AET40320.1 - 4e-07 30.0 13.9 0.034 14.2 4.3 4.8 3 2 2 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AET40320.1 - 0.00021 21.5 22.1 0.43 11.1 0.1 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 AET40320.1 - 0.00039 19.6 8.2 0.46 9.7 0.0 6.2 7 0 0 7 7 7 1 SHNi-TPR RPN7 PF10602.4 AET40320.1 - 0.0015 17.9 19.6 0.061 12.6 0.1 5.4 3 2 3 6 6 6 2 26S proteasome subunit RPN7 TPR_10 PF13374.1 AET40320.1 - 0.0019 18.0 15.1 0.42 10.6 0.1 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AET40320.1 - 0.035 13.9 7.0 5.6 6.9 0.1 5.2 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat PPR_2 PF13041.1 AET40320.1 - 0.046 13.7 0.9 1.2e+02 2.7 0.0 4.8 5 0 0 5 5 5 0 PPR repeat family TPR_20 PF14561.1 AET40320.1 - 0.091 12.8 11.3 4.5 7.4 0.0 4.7 4 2 0 4 4 4 0 Tetratricopeptide repeat YfdX PF10938.3 AET40320.1 - 0.49 10.0 14.4 0.24 11.0 2.8 4.1 3 1 0 3 3 3 0 YfdX protein PPR PF01535.15 AET40320.1 - 1.1 9.4 10.2 56 4.0 0.0 6.3 8 0 0 8 8 8 0 PPR repeat SET PF00856.23 AET40321.1 - 7.9e-05 23.0 0.0 0.00038 20.7 0.0 2.1 1 1 0 1 1 1 1 SET domain WD40 PF00400.27 AET40322.1 - 1.2e-10 40.8 4.9 6.7e-07 28.9 0.1 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat DUF3553 PF12073.3 AET40322.1 - 0.0055 15.9 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3553) Apc4_WD40 PF12894.2 AET40322.1 - 0.044 13.2 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 AET40322.1 - 0.086 11.0 0.7 0.25 9.5 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) Pex24p PF06398.6 AET40323.1 - 5.5e-77 258.9 8.1 6.9e-77 258.6 5.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4241 PF14025.1 AET40323.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Rpr2 PF04032.11 AET40324.1 - 1.6e-14 53.4 0.7 3.6e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.1 AET40324.1 - 0.013 14.6 1.3 0.17 11.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AET40324.1 - 0.051 13.0 1.3 4.3 6.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 AET40324.1 - 0.2 11.3 1.4 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal SIR2 PF02146.12 AET40325.1 - 1.5e-36 125.7 0.0 2.7e-35 121.6 0.0 2.4 1 1 0 1 1 1 1 Sir2 family DUF573 PF04504.9 AET40325.1 - 0.0086 16.3 2.6 0.014 15.6 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF573 DUF2256 PF10013.4 AET40325.1 - 0.011 15.4 0.3 0.027 14.2 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF1257 PF06868.6 AET40325.1 - 0.051 13.4 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Pkinase PF00069.20 AET40326.1 - 1.3e-76 257.1 0.1 2.1e-76 256.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40326.1 - 7.6e-39 133.3 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 AET40326.1 - 8.7e-17 61.0 2.2 8.7e-17 61.0 1.5 2.2 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 AET40326.1 - 9.2e-10 37.9 0.0 2.3e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AET40326.1 - 3.3e-05 23.3 0.4 7.4e-05 22.1 0.3 1.5 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 AET40326.1 - 3.4e-05 22.6 0.3 7.2e-05 21.5 0.2 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 AET40326.1 - 0.0028 16.7 0.1 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET40326.1 - 0.028 14.1 0.1 0.7 9.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2470 PF10615.4 AET40327.1 - 1.8e-18 66.5 0.3 2.5e-18 66.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Adeno_E3_CR2 PF02439.10 AET40327.1 - 0.045 13.2 0.3 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 SDA1 PF05285.7 AET40328.1 - 0.095 11.9 10.8 0.2 10.9 7.5 1.5 1 0 0 1 1 1 0 SDA1 Amidinotransf PF02274.12 AET40328.1 - 0.098 11.7 0.0 0.23 10.5 0.0 1.5 1 1 0 1 1 1 0 Amidinotransferase Nop14 PF04147.7 AET40328.1 - 4.1 5.2 15.1 6.3 4.5 10.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AET40328.1 - 6.8 4.5 11.1 13 3.7 7.7 1.3 1 0 0 1 1 1 0 CDC45-like protein PRP3 PF08572.5 AET40329.1 - 4.9e-57 192.8 22.0 4.9e-57 192.8 15.3 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 AET40329.1 - 2e-31 108.3 0.2 2e-31 108.3 0.1 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) Cpn10 PF00166.16 AET40330.1 - 2.1e-27 94.9 0.2 2.3e-27 94.7 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF2611 PF11022.3 AET40331.1 - 4.3e-18 65.1 0.1 4.9e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Nol1_Nop2_Fmu_2 PF13636.1 AET40331.1 - 0.037 14.1 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis RNA_Me_trans PF04252.8 AET40332.1 - 9.6e-71 237.2 0.0 1.1e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DDHD PF02862.12 AET40333.1 - 1.4e-41 142.8 1.0 3.4e-29 102.2 0.0 2.5 2 1 1 3 3 3 2 DDHD domain LCAT PF02450.10 AET40333.1 - 8.5e-08 31.5 0.0 2.4e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 AET40333.1 - 1.7e-05 24.2 0.0 0.0029 16.9 0.0 2.4 2 0 0 2 2 2 2 Putative serine esterase (DUF676) SIR2_2 PF13289.1 AET40333.1 - 0.016 15.1 0.1 8.2 6.3 0.0 2.6 2 0 0 2 2 2 0 SIR2-like domain DUF2305 PF10230.4 AET40333.1 - 0.02 14.3 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 AET40333.1 - 0.046 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF3089 PF11288.3 AET40333.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_1 PF00561.15 AET40333.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DivIC PF04977.10 AET40334.1 - 0.3 10.5 4.2 1 8.9 2.9 1.9 1 0 0 1 1 1 0 Septum formation initiator 4F5 PF04419.9 AET40335.1 - 8.6e-10 39.1 8.3 8.6e-10 39.1 5.8 2.4 2 1 0 2 2 2 1 4F5 protein family WD40 PF00400.27 AET40336.1 - 3.1e-25 87.0 2.0 7.3e-05 22.5 0.0 6.6 6 1 1 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 AET40336.1 - 0.0016 17.9 0.0 0.013 14.9 0.0 2.1 2 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 AET40336.1 - 0.052 13.8 2.8 0.62 10.4 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain RAB3GAP2_N PF14655.1 AET40336.1 - 0.065 12.2 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DLH PF01738.13 AET40337.1 - 2.3e-21 76.1 0.0 2.8e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AET40337.1 - 0.00088 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 AET40337.1 - 0.0027 17.1 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 AET40337.1 - 0.0075 15.5 0.1 0.02 14.1 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 AET40337.1 - 0.063 12.9 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AAA_24 PF13479.1 AET40338.1 - 0.06 12.9 1.1 0.089 12.3 0.8 1.2 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpc4 PF05132.9 AET40339.1 - 0.3 11.0 4.4 0.6 10.1 3.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ribophorin_II PF05817.9 AET40340.1 - 2.2e-06 26.2 0.5 2.7e-06 25.8 0.4 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Scs3p PF10261.4 AET40340.1 - 0.21 10.5 2.0 0.35 9.8 1.4 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Peptidase_S24 PF00717.18 AET40341.1 - 9.8e-07 28.3 0.1 4.6e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 AET40341.1 - 0.00032 20.2 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 adh_short PF00106.20 AET40342.1 - 0.0022 17.9 0.1 0.22 11.4 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase LUC7 PF03194.10 AET40343.1 - 3.1e-69 233.3 7.8 3.9e-69 232.9 5.4 1.1 1 0 0 1 1 1 1 LUC7 N_terminus APG6 PF04111.7 AET40343.1 - 0.036 13.1 1.7 0.065 12.2 1.2 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Rho_Binding PF08912.6 AET40343.1 - 0.072 13.4 2.5 0.44 10.8 0.1 3.0 3 0 0 3 3 3 0 Rho Binding FlaC_arch PF05377.6 AET40343.1 - 0.18 11.6 1.1 1.7 8.5 0.4 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HDV_ag PF01517.13 AET40343.1 - 0.34 10.5 2.4 0.42 10.2 0.1 2.1 2 1 1 3 3 3 0 Hepatitis delta virus delta antigen Med4 PF10018.4 AET40343.1 - 0.68 9.2 5.0 9.1 5.6 3.5 2.2 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Nup35_RRM PF05172.8 AET40344.1 - 2.5e-32 110.6 0.1 6.9e-32 109.2 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 AET40344.1 - 9.5e-05 22.0 0.1 0.00095 18.8 0.0 2.4 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif GATase_6 PF13522.1 AET40344.1 - 0.0054 16.6 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Copper-bind PF00127.15 AET40344.1 - 0.072 13.3 1.2 0.2 11.8 0.8 1.7 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Radial_spoke_3 PF06098.6 AET40344.1 - 1.3 7.9 4.2 0.25 10.3 0.2 1.7 2 0 0 2 2 2 0 Radial spoke protein 3 DUF2418 PF10332.4 AET40345.1 - 1.1e-25 89.7 1.9 3.4e-25 88.2 1.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Calpain_III PF01067.17 AET40346.1 - 3e-05 23.7 1.1 0.0022 17.6 0.0 3.3 2 1 0 2 2 2 1 Calpain large subunit, domain III DUF1106 PF06523.6 AET40346.1 - 0.063 13.1 2.4 0.37 10.6 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1106) Prenyltrans PF00432.16 AET40347.1 - 2.5e-32 110.0 3.4 2e-12 46.4 0.2 5.6 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AET40347.1 - 2.5e-20 72.9 0.0 2.7e-13 50.2 0.0 3.1 1 1 2 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 AET40347.1 - 0.00025 21.0 0.0 0.00092 19.1 0.0 2.0 1 1 0 1 1 1 1 Prenyltransferase-like A2M_comp PF07678.9 AET40347.1 - 0.054 12.7 0.0 5.3 6.1 0.0 2.4 1 1 1 2 2 2 0 A-macroglobulin complement component UBX PF00789.15 AET40348.1 - 3.5e-15 55.8 0.0 1.2e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 UBX domain SRP14 PF02290.10 AET40349.1 - 6.8e-16 57.9 1.1 9.8e-16 57.4 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Nodulin-like PF06813.8 AET40350.1 - 4e-13 49.2 2.0 4e-13 49.2 1.4 2.6 2 1 0 2 2 2 1 Nodulin-like Spc7_N PF15402.1 AET40350.1 - 0.72 7.7 3.8 0.96 7.3 2.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PMT PF02366.13 AET40351.1 - 3.3e-81 272.2 19.2 3.3e-81 272.2 13.3 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AET40351.1 - 1.7e-56 190.7 0.4 2.5e-56 190.2 0.3 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 AET40351.1 - 1e-05 25.4 15.1 1e-05 25.4 10.5 3.3 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PCI PF01399.22 AET40352.1 - 9.5e-18 64.4 0.1 5.8e-17 61.9 0.0 2.4 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 AET40352.1 - 0.0022 18.6 2.2 0.51 11.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AET40352.1 - 0.88 9.7 15.6 0.13 12.4 1.0 4.0 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-C2H2_jaz PF12171.3 AET40353.1 - 1.2e-05 25.2 1.2 3.4e-05 23.8 0.9 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AET40353.1 - 1.3e-05 25.1 0.6 3.2e-05 23.9 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SRP-alpha_N PF04086.8 AET40353.1 - 0.0076 15.6 0.9 0.014 14.7 0.6 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal zf-C2H2_6 PF13912.1 AET40353.1 - 0.017 14.9 0.9 0.037 13.9 0.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1777 PF08648.7 AET40353.1 - 0.024 14.3 0.8 0.024 14.3 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) zf-C2H2_2 PF12756.2 AET40353.1 - 0.032 14.3 1.1 0.055 13.5 0.8 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Tex_N PF09371.5 AET40354.1 - 0.086 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF2762 PF10960.3 AET40354.1 - 0.12 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) Ribosomal_S8 PF00410.14 AET40355.1 - 2.4e-18 66.2 0.0 3.2e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DUF848 PF05852.6 AET40356.1 - 0.00014 21.7 8.9 0.00014 21.7 6.2 2.5 1 1 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) IncA PF04156.9 AET40356.1 - 0.0002 21.0 7.8 0.0002 21.0 5.4 2.1 2 0 0 2 2 2 1 IncA protein TMF_DNA_bd PF12329.3 AET40356.1 - 0.00021 21.0 14.5 0.00021 21.0 10.0 2.7 3 0 0 3 3 2 1 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.2 AET40356.1 - 0.00029 20.2 8.1 0.00029 20.2 5.6 2.1 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain SlyX PF04102.7 AET40356.1 - 0.00075 19.8 7.8 0.00075 19.8 5.4 3.1 2 1 1 3 3 3 1 SlyX Tho2 PF11262.3 AET40356.1 - 0.0012 18.0 2.3 0.0012 18.0 1.6 2.1 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Lebercilin PF15619.1 AET40356.1 - 0.0012 18.2 3.7 0.0012 18.2 2.6 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Mod_r PF07200.8 AET40356.1 - 0.0085 16.0 7.9 0.0085 16.0 5.5 2.2 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Striatin PF08232.7 AET40356.1 - 0.01 16.1 20.2 0.018 15.3 3.0 2.4 2 0 0 2 2 2 0 Striatin family CP12 PF02672.10 AET40356.1 - 0.12 12.8 12.0 1.4 9.4 0.7 2.8 2 1 1 3 3 3 0 CP12 domain ACCA PF03255.9 AET40356.1 - 0.15 11.5 12.4 0.098 12.2 0.7 3.1 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Mitofilin PF09731.4 AET40356.1 - 0.18 10.4 29.3 0.26 9.9 20.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Seryl_tRNA_N PF02403.17 AET40356.1 - 0.31 11.0 18.6 0.1 12.6 3.8 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Herpes_UL6 PF01763.11 AET40356.1 - 0.37 8.9 21.8 0.005 15.0 6.9 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like TBPIP PF07106.8 AET40356.1 - 0.38 10.2 26.0 0.04 13.4 6.3 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 AET40356.1 - 0.41 10.2 23.0 0.32 10.6 4.6 2.2 2 0 0 2 2 2 0 Mnd1 family Reo_sigmaC PF04582.7 AET40356.1 - 0.6 9.2 8.7 0.71 8.9 5.9 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF148 PF02520.12 AET40356.1 - 0.76 9.5 23.3 0.34 10.7 4.9 3.2 1 1 1 3 3 3 0 Domain of unknown function DUF148 YvrJ PF12841.2 AET40356.1 - 0.92 8.8 4.4 2.1 7.6 0.8 2.4 2 0 0 2 2 2 0 YvrJ protein family Macoilin PF09726.4 AET40356.1 - 1.2 7.3 20.3 1.8 6.7 14.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Frigida PF07899.6 AET40356.1 - 1.3 7.6 17.0 0.045 12.5 1.3 2.2 2 0 0 2 2 2 0 Frigida-like protein NPV_P10 PF05531.7 AET40356.1 - 2.7 8.2 11.6 0.19 11.9 3.1 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 AET40356.1 - 7.6 3.7 25.2 0.053 10.8 7.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Peptidase_S64 PF08192.6 AET40356.1 - 8 4.6 19.1 9.1 4.4 13.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 ATG16 PF08614.6 AET40356.1 - 9 6.0 23.8 21 4.8 16.5 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 AET40356.1 - 9.2 6.2 14.4 4.2 7.3 1.2 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TSC22 PF01166.13 AET40356.1 - 9.8 6.2 15.2 0.81 9.6 1.3 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family ArsA_ATPase PF02374.10 AET40357.1 - 7.9e-116 386.3 0.2 9.1e-116 386.1 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 AET40357.1 - 4.2e-13 49.1 0.1 7.1e-13 48.4 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AET40357.1 - 5.1e-05 23.2 0.6 0.00023 21.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 AET40357.1 - 0.0012 18.3 0.0 0.31 10.4 0.0 2.4 2 1 0 2 2 2 2 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 AET40357.1 - 0.0013 18.0 0.1 0.0023 17.1 0.1 1.6 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 AET40357.1 - 0.017 14.5 0.0 0.074 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Lectin_N PF03954.9 AET40357.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2075 PF09848.4 AET40357.1 - 0.064 12.2 0.1 0.31 9.9 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 AET40357.1 - 0.064 12.3 0.0 0.41 9.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 AET40357.1 - 0.078 11.8 0.1 0.23 10.3 0.0 1.8 3 0 0 3 3 3 0 Type II/IV secretion system protein ATG16 PF08614.6 AET40358.1 - 5e-23 81.9 17.0 5.7e-21 75.2 7.9 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Fez1 PF06818.10 AET40358.1 - 0.003 17.6 1.8 0.0048 16.9 1.3 1.2 1 0 0 1 1 1 1 Fez1 Macoilin PF09726.4 AET40358.1 - 0.0032 15.8 1.6 0.0035 15.7 1.1 1.0 1 0 0 1 1 1 1 Transmembrane protein GAS PF13851.1 AET40358.1 - 0.0033 16.6 5.1 0.0054 15.9 3.6 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 AET40358.1 - 0.011 15.4 1.2 0.02 14.6 0.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.4 AET40358.1 - 0.013 15.4 1.2 0.023 14.7 0.8 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF86 PF01934.12 AET40358.1 - 0.067 12.8 0.9 0.077 12.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF86 ADIP PF11559.3 AET40358.1 - 0.17 11.7 7.3 1.6 8.5 0.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 AET40358.1 - 0.36 10.4 3.5 0.38 10.3 2.4 1.3 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 AET40358.1 - 0.42 11.0 3.3 1.5 9.3 0.2 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 AET40358.1 - 1.7 8.6 7.8 2.2 8.3 1.3 2.4 1 1 2 3 3 3 0 bZIP transcription factor Herpes_BLRF2 PF05812.7 AET40358.1 - 3.7 7.3 6.3 2 8.2 0.2 2.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein TSC22 PF01166.13 AET40358.1 - 6.2 6.8 6.7 8.7 6.3 0.8 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family Pkinase PF00069.20 AET40360.1 - 1.1e-69 234.4 0.0 1.5e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40360.1 - 2.7e-35 121.7 0.0 3.4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AET40360.1 - 5.9e-18 64.7 0.3 1.5e-17 63.4 0.2 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 AET40360.1 - 0.0029 16.6 2.3 0.75 8.7 0.5 3.4 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 AET40360.1 - 0.0033 16.5 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_excise PF03013.9 AET40360.1 - 0.073 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase DNA_pol_B PF00136.16 AET40361.1 - 2.1e-135 452.1 0.2 2.9e-135 451.6 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AET40361.1 - 1e-85 287.5 0.0 1.6e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AET40361.1 - 3.8e-24 84.4 4.0 7.4e-24 83.5 2.8 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 AET40361.1 - 0.00015 20.6 1.1 0.0024 16.6 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 AET40361.1 - 0.00036 20.3 0.2 0.0015 18.3 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 AET40361.1 - 0.0018 17.8 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DnaJ PF00226.26 AET40362.1 - 5.6e-25 86.8 3.2 9e-25 86.1 2.2 1.3 1 0 0 1 1 1 1 DnaJ domain E1-E2_ATPase PF00122.15 AET40363.1 - 2.5e-19 69.2 0.0 5.9e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AET40363.1 - 2.2e-15 57.6 0.2 2e-11 44.7 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 AET40363.1 - 6.5e-13 49.2 1.2 2.3e-11 44.2 0.8 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AET40363.1 - 3.7e-12 46.0 0.0 1.2e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AET40363.1 - 0.0044 16.6 0.4 0.0044 16.6 0.3 2.8 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase UDPGP PF01704.13 AET40364.1 - 1.5e-49 168.6 0.0 2.1e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 AET40364.1 - 0.0068 16.5 0.0 0.019 15.0 0.0 1.7 2 0 0 2 2 2 1 MobA-like NTP transferase domain Catalase-rel PF06628.7 AET40364.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Catalase-related immune-responsive Vezatin PF12632.2 AET40365.1 - 1e-33 116.4 13.4 1e-33 116.4 9.3 2.2 3 0 0 3 3 3 1 Mysoin-binding motif of peroxisomes DUF2262 PF10020.4 AET40365.1 - 0.0096 16.1 0.3 0.041 14.0 0.0 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2262) P3A PF08727.6 AET40365.1 - 0.053 12.8 0.1 0.19 11.0 0.1 2.0 1 0 0 1 1 1 0 Poliovirus 3A protein like LisH PF08513.6 AET40366.1 - 8.7e-08 31.6 0.7 1.4e-07 30.9 0.5 1.4 1 0 0 1 1 1 1 LisH LNS2 PF08235.8 AET40367.1 - 3.5e-72 241.1 0.0 6.5e-72 240.2 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 AET40367.1 - 6e-44 148.2 0.0 1.5e-43 146.9 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 AET40367.1 - 0.0059 16.0 0.3 0.023 14.0 0.0 2.0 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.1 AET40367.1 - 0.03 14.2 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Mito_carr PF00153.22 AET40368.1 - 1.9e-64 213.3 2.0 6.8e-21 73.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M22 PF00814.20 AET40369.1 - 2.8e-68 230.2 0.0 3.3e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.15 AET40369.1 - 0.056 12.7 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF2526 PF10735.4 AET40369.1 - 0.091 12.7 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) Nse4_C PF08743.5 AET40370.1 - 6.6e-21 74.1 0.0 2e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 AET40370.1 - 4.1e-10 39.3 0.3 7.8e-10 38.4 0.2 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE WD40 PF00400.27 AET40371.1 - 1.1e-34 117.1 3.7 1.5e-09 37.3 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 AET40371.1 - 1.8e-08 33.0 1.2 0.0013 16.9 0.1 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AET40371.1 - 6.1e-05 21.9 2.3 0.91 8.1 0.1 4.2 1 1 3 4 4 4 3 Nup133 N terminal like AlaDh_PNT_N PF05222.10 AET40372.1 - 5.9e-31 107.2 0.0 9.2e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 AET40372.1 - 1.9e-15 56.8 0.1 4.2e-15 55.7 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain PS_pyruv_trans PF04230.8 AET40372.1 - 0.035 13.7 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase TPR_1 PF00515.23 AET40373.1 - 3.2e-42 140.4 9.1 6.8e-06 25.4 0.0 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 AET40373.1 - 5e-36 119.7 6.5 0.00015 21.4 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 AET40373.1 - 3.3e-34 116.3 9.5 2.3e-08 33.5 0.0 7.2 5 2 0 6 6 6 5 TPR repeat Apc3 PF12895.2 AET40373.1 - 2.2e-31 107.8 11.6 3e-21 75.3 0.1 5.7 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 AET40373.1 - 2.3e-26 91.5 5.9 1.2e-07 31.5 0.0 7.8 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 AET40373.1 - 2.2e-23 80.2 8.9 2.3e-05 23.8 0.1 8.9 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 AET40373.1 - 6.1e-22 77.7 0.0 0.00013 22.5 0.0 6.7 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 AET40373.1 - 1.4e-20 73.3 0.9 0.00021 21.5 0.0 7.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 AET40373.1 - 7.5e-19 66.5 0.0 0.025 15.1 0.0 8.4 6 2 4 10 10 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 AET40373.1 - 5.4e-18 63.6 3.5 0.0099 16.0 0.0 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 AET40373.1 - 5.7e-13 47.6 7.3 0.0073 16.0 0.0 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 AET40373.1 - 5.1e-12 45.3 1.0 0.55 10.2 0.0 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 AET40373.1 - 2.2e-11 43.4 7.4 1.3 9.5 0.1 8.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 AET40373.1 - 4.7e-08 32.4 0.1 0.16 11.0 0.0 4.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 AET40373.1 - 8.7e-08 31.9 0.2 0.0091 15.8 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 AET40373.1 - 1e-06 28.3 1.3 0.13 12.0 0.0 4.7 6 0 0 6 6 4 1 Tetratricopeptide repeat ChAPs PF09295.5 AET40373.1 - 0.00035 19.4 0.5 0.069 11.8 0.0 3.5 3 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 AET40373.1 - 0.00044 20.0 6.4 6.3 6.7 0.0 5.7 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 AET40373.1 - 0.0066 16.5 0.4 7 6.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.1 AET40373.1 - 0.022 13.9 4.7 10 5.1 0.0 3.9 3 2 0 3 3 3 0 Soluble NSF attachment protein, SNAP SPO22 PF08631.5 AET40373.1 - 0.32 10.0 4.0 5.3 6.0 0.0 3.1 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like TPR_21 PF09976.4 AET40373.1 - 0.5 10.3 3.6 27 4.6 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat ADK PF00406.17 AET40374.1 - 6.2e-45 152.7 0.0 8.5e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 AET40374.1 - 5.9e-10 39.5 0.0 9.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AET40374.1 - 1e-08 35.1 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AET40374.1 - 1.1e-07 32.7 0.0 1.6e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 AET40374.1 - 8.4e-05 22.0 0.2 0.14 11.5 0.0 2.2 1 1 1 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 AET40374.1 - 0.00051 19.1 0.0 0.00072 18.6 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin adh_short PF00106.20 AET40375.1 - 2.5e-30 105.5 0.1 3.6e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AET40375.1 - 2.4e-14 53.7 0.1 2.8e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AET40375.1 - 1.1e-11 44.7 0.1 1.8e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AET40375.1 - 0.00013 21.4 0.2 0.00061 19.2 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AET40375.1 - 0.0019 18.2 0.1 0.0033 17.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 AET40375.1 - 0.026 14.5 0.1 0.053 13.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Peptidase_S10 PF00450.17 AET40377.1 - 9.2e-127 423.6 0.4 1.2e-126 423.2 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 AET40377.1 - 1.6e-16 60.4 0.1 3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Baculo_DNA_bind PF04786.7 AET40377.1 - 0.11 11.5 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 ssDNA binding protein Ndc80_HEC PF03801.8 AET40378.1 - 0.057 12.8 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family Cbl_N3 PF02762.9 AET40378.1 - 0.078 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain DUF3591 PF12157.3 AET40379.1 - 1.6e-199 663.0 1.7 3.2e-199 662.0 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 AET40379.1 - 8e-08 31.8 0.7 1.8e-07 30.6 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Rtt102p PF09510.5 AET40380.1 - 1.1e-27 96.5 0.1 1.1e-27 96.5 0.1 2.0 2 1 0 2 2 2 1 Rtt102p-like transcription regulator protein RNase_T PF00929.19 AET40381.1 - 6.5e-26 91.5 0.1 1.2e-25 90.6 0.1 1.5 1 0 0 1 1 1 1 Exonuclease DLIC PF05783.6 AET40382.1 - 1.2e-05 24.2 0.0 2.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) GATase_2 PF00310.16 AET40383.1 - 1.9e-24 86.0 0.0 2.4e-17 62.7 0.0 2.5 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AET40383.1 - 1.6e-14 53.9 0.0 3.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 AET40383.1 - 2.7e-13 49.7 0.1 4.8e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 AET40383.1 - 1.5e-12 47.3 0.0 2.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 AET40383.1 - 0.00021 20.0 0.0 0.00035 19.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PTSIIB_sorb PF03830.10 AET40383.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component ABC_membrane PF00664.18 AET40384.1 - 3.7e-35 121.6 17.7 4.6e-35 121.3 12.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AET40384.1 - 4.2e-34 117.7 0.0 7.8e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 AET40384.1 - 1.4e-09 37.4 0.2 1.5e-05 24.3 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AET40384.1 - 1.9e-09 37.8 3.7 1.8e-05 24.8 0.1 3.7 3 2 0 3 3 3 1 AAA domain AAA_29 PF13555.1 AET40384.1 - 3.2e-05 23.3 0.2 7.6e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 AET40384.1 - 0.00028 20.9 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 AET40384.1 - 0.002 18.9 0.0 0.0054 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AET40384.1 - 0.0034 17.5 0.0 0.012 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AET40384.1 - 0.0076 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 AET40384.1 - 0.012 15.9 0.1 0.012 15.9 0.1 2.3 3 1 0 3 3 3 0 AAA domain ABC_ATPase PF09818.4 AET40384.1 - 0.014 14.0 0.2 0.59 8.6 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_14 PF13173.1 AET40384.1 - 0.015 15.1 0.0 0.064 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 AET40384.1 - 0.02 14.0 0.0 0.057 12.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 AET40384.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 AET40384.1 - 0.038 14.2 0.1 0.15 12.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AET40384.1 - 0.05 13.5 1.3 0.16 11.8 0.2 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 AET40384.1 - 0.097 12.1 0.0 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 AET40384.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AET40384.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 AET40384.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Proteasome PF00227.21 AET40385.1 - 2.3e-47 160.7 0.1 2.8e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AET40385.1 - 1.1e-12 47.0 0.2 1.9e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1250 PF06855.7 AET40385.1 - 0.18 11.3 0.5 1.6 8.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1250) DUF3336 PF11815.3 AET40386.1 - 1.5e-28 99.1 0.0 2.6e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AET40386.1 - 1.9e-09 37.7 0.0 3.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF2535 PF10751.4 AET40386.1 - 0.0095 16.0 0.6 0.052 13.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2535) DUF2348 PF09807.4 AET40387.1 - 0.058 12.4 0.1 0.27 10.3 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2348) SURF4 PF02077.10 AET40388.1 - 5.5e-94 314.4 12.2 6.2e-94 314.2 8.5 1.0 1 0 0 1 1 1 1 SURF4 family IPP-2 PF04979.9 AET40389.1 - 0.00012 22.3 18.8 0.00012 22.3 8.5 2.9 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Glyco_hydro_17 PF00332.13 AET40390.1 - 3.8e-63 213.4 0.1 4.3e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 eIF-3c_N PF05470.7 AET40391.1 - 5.6e-156 520.0 2.5 3.5e-120 401.8 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 AET40391.1 - 5.2e-09 36.3 1.8 1.7e-08 34.7 0.2 2.8 3 1 0 3 3 3 1 PCI domain HMG_box PF00505.14 AET40392.1 - 0.066 13.4 7.9 1.4 9.2 0.0 3.0 3 0 0 3 3 3 0 HMG (high mobility group) box Med15 PF09606.5 AET40392.1 - 0.12 10.5 40.1 0.19 9.8 27.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Vma12 PF11712.3 AET40392.1 - 0.25 11.0 4.1 0.78 9.4 2.8 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Spt5_N PF11942.3 AET40392.1 - 0.28 11.7 12.0 1.2 9.7 8.3 2.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal ABC_membrane PF00664.18 AET40393.1 - 5.6e-58 196.5 47.9 4.8e-34 118.0 13.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AET40393.1 - 6.2e-50 169.0 0.4 3.3e-29 101.9 0.1 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AET40393.1 - 6.1e-09 36.2 0.0 0.027 14.4 0.0 4.1 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 AET40393.1 - 9.3e-09 34.8 0.0 0.012 14.8 0.1 4.2 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AET40393.1 - 1.3e-07 31.0 1.8 0.0059 16.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AET40393.1 - 7.3e-07 28.5 1.6 0.0049 16.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 AET40393.1 - 1.4e-06 29.0 0.1 0.066 14.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AET40393.1 - 1.6e-06 28.5 7.3 0.0095 16.2 2.9 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AET40393.1 - 1.1e-05 25.6 0.7 0.12 12.6 0.2 2.9 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 AET40393.1 - 2.5e-05 23.3 0.3 0.032 13.1 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 AET40393.1 - 5.5e-05 23.2 2.2 0.054 13.4 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 AET40393.1 - 0.00037 20.0 2.1 0.17 11.2 0.0 3.0 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_22 PF13401.1 AET40393.1 - 0.00048 20.2 0.6 1.5 8.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 AET40393.1 - 0.001 18.7 0.6 0.047 13.4 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 AET40393.1 - 0.0013 18.7 5.8 0.057 13.3 0.1 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase Miro PF08477.8 AET40393.1 - 0.0015 19.0 0.5 1.8 9.1 0.0 3.1 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 AET40393.1 - 0.0017 18.3 1.5 0.036 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AET40393.1 - 0.002 17.5 0.6 0.25 10.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 AET40393.1 - 0.006 16.1 0.1 2.7 7.4 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 AET40393.1 - 0.014 15.0 1.1 0.15 11.6 0.1 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 AET40393.1 - 0.014 14.9 9.7 0.43 10.1 0.0 3.8 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 AET40393.1 - 0.02 14.7 4.3 0.86 9.4 0.0 3.2 3 0 0 3 3 3 0 Dynamin family IstB_IS21 PF01695.12 AET40393.1 - 0.021 14.2 5.2 0.6 9.5 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 AET40393.1 - 0.026 13.6 0.3 2.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 AET40393.1 - 0.028 13.4 0.6 0.066 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 AET40393.1 - 0.029 13.9 1.0 3.1 7.2 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 AET40393.1 - 0.036 13.7 1.8 3.4 7.3 0.2 2.5 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 AET40393.1 - 0.041 14.0 0.2 6.8 6.9 0.0 3.2 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 AET40393.1 - 0.053 13.4 0.9 3 7.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 AET40393.1 - 0.068 11.9 0.8 0.41 9.3 0.1 2.2 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 AET40393.1 - 0.16 11.4 2.8 0.37 10.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CBS PF00571.23 AET40394.1 - 6.7e-28 96.2 0.1 1.5e-06 27.9 0.0 4.6 4 1 0 4 4 4 4 CBS domain Fungal_trans PF04082.13 AET40395.1 - 3.4e-20 72.0 1.3 9.8e-20 70.5 0.6 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain INTS5_N PF14837.1 AET40395.1 - 0.0022 17.4 0.0 0.78 9.1 0.0 2.5 2 0 0 2 2 2 2 Integrator complex subunit 5 N-terminus HEAT_EZ PF13513.1 AET40396.1 - 6.5e-19 67.8 4.1 7.6e-06 26.2 0.0 10.1 10 1 2 12 12 12 3 HEAT-like repeat HEAT_2 PF13646.1 AET40396.1 - 2.6e-18 66.0 0.1 5.1e-07 29.8 0.0 5.8 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.17 AET40396.1 - 1.7e-16 58.7 7.5 0.008 16.1 0.0 9.5 10 0 0 10 10 10 5 HEAT repeat Adaptin_N PF01602.15 AET40396.1 - 6.1e-08 31.4 3.4 0.34 9.1 0.0 4.6 3 1 0 4 4 4 4 Adaptin N terminal region MMS19_C PF12460.3 AET40396.1 - 2.3e-07 29.9 8.3 0.00068 18.4 0.4 4.8 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal Arm PF00514.18 AET40396.1 - 4.5e-07 29.4 0.3 6.8 6.6 0.0 5.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 AET40396.1 - 7.1e-06 26.3 0.0 0.084 13.2 0.0 5.4 4 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AET40396.1 - 2e-05 24.1 0.7 0.0032 16.8 0.5 4.4 4 2 1 5 5 5 1 CLASP N terminal DUF3385 PF11865.3 AET40396.1 - 0.0099 15.8 0.6 1 9.2 0.1 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) G-patch PF01585.18 AET40397.1 - 6.3e-10 38.6 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 AET40397.1 - 7.4e-05 22.5 0.1 7.4e-05 22.5 0.0 4.0 2 1 0 2 2 2 1 DExH-box splicing factor binding site MIP-T3 PF10243.4 AET40397.1 - 0.23 9.8 49.4 0.31 9.4 34.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 AET40397.1 - 0.27 9.2 21.9 0.37 8.7 15.2 1.3 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 AET40397.1 - 0.31 9.8 17.4 0.41 9.4 12.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein UPF0560 PF10577.4 AET40397.1 - 0.91 7.7 19.4 1.1 7.4 13.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SOBP PF15279.1 AET40397.1 - 2.7 8.3 14.8 4.3 7.6 10.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 AET40397.1 - 9.2 3.8 24.5 14 3.2 17.0 1.3 1 0 0 1 1 1 0 Ycf1 Glyco_hydro_72 PF03198.9 AET40398.1 - 4.4e-144 479.2 4.3 5.7e-144 478.8 3.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 AET40398.1 - 2.2e-25 88.9 5.7 6.4e-25 87.4 3.9 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 AET40398.1 - 0.00028 20.1 0.0 0.0022 17.2 0.0 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rep_1 PF01446.12 AET40398.1 - 0.23 10.7 0.0 0.76 9.0 0.0 1.7 2 0 0 2 2 2 0 Replication protein Glyco_hydro_72 PF03198.9 AET40399.1 - 6.4e-140 465.5 6.2 8.6e-140 465.1 4.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 AET40399.1 - 2.6e-23 82.3 5.0 5.4e-23 81.2 2.7 2.3 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.13 AET40399.1 - 0.0013 18.0 0.0 0.013 14.6 0.0 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_17 PF00332.13 AET40400.1 - 3.2e-07 29.6 0.2 1.4e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF605 PF04652.11 AET40400.1 - 0.0088 15.4 14.8 0.014 14.8 10.3 1.3 1 0 0 1 1 1 1 Vta1 like PhageMin_Tail PF10145.4 AET40400.1 - 0.08 12.5 0.0 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Phage-related minor tail protein MarR PF01047.17 AET40400.1 - 0.27 10.9 0.5 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 MarR family MA3 PF02847.12 AET40401.1 - 2e-20 72.5 0.3 3.5e-19 68.5 0.0 2.6 2 0 0 2 2 2 1 MA3 domain DUF204 PF02659.10 AET40401.1 - 0.036 14.1 0.2 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF CTP_transf_2 PF01467.21 AET40402.1 - 1.1e-13 51.5 0.0 1.6e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase UCH PF00443.24 AET40403.1 - 1.1e-53 182.0 1.9 2.2e-53 181.1 1.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 AET40403.1 - 3.2e-53 180.3 10.9 5.9e-53 179.4 1.7 3.5 3 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.3 AET40403.1 - 6.2e-36 123.9 0.8 4e-35 121.2 0.0 2.6 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 AET40403.1 - 6.5e-33 114.4 0.0 2.4e-32 112.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ADH_zinc_N PF00107.21 AET40404.1 - 1.3e-18 66.8 0.1 3.2e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Biotin_lipoyl_2 PF13533.1 AET40404.1 - 0.013 15.1 0.0 0.53 9.9 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like Zn_clus PF00172.13 AET40405.1 - 1.2e-07 31.5 7.9 2.5e-07 30.4 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AET40405.1 - 3.1e-07 29.3 0.4 4.9e-07 28.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.10 AET40406.1 - 4.8e-73 246.2 29.5 6.2e-73 245.8 20.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FH2 PF02181.18 AET40408.1 - 3.9e-63 213.5 9.0 3.9e-63 213.5 6.2 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 AET40408.1 - 4e-08 32.9 5.1 3.2e-07 29.9 2.0 2.8 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 AET40408.1 - 4.6e-08 32.6 0.4 4.6e-08 32.6 0.3 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain CheB_methylest PF01339.12 AET40408.1 - 0.12 11.7 0.1 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 CheB methylesterase Hexokinase_2 PF03727.11 AET40409.1 - 3.1e-95 318.0 0.0 4e-95 317.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 AET40409.1 - 2.8e-79 265.2 0.0 3.6e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 AET40409.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain SAC3_GANP PF03399.11 AET40410.1 - 1.7e-29 102.8 1.9 2.2e-29 102.5 1.3 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 AET40410.1 - 5.8e-19 68.2 0.7 9.1e-19 67.6 0.5 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Ppx-GppA PF02541.11 AET40411.1 - 1.3e-63 214.9 0.0 1.7e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF3136 PF11334.3 AET40411.1 - 0.095 12.1 0.2 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) Sec63 PF02889.11 AET40412.1 - 8.2e-48 163.2 2.9 8.7e-48 163.1 0.7 1.9 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.24 AET40412.1 - 4.6e-26 91.3 0.1 5e-25 87.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET40412.1 - 6.7e-12 45.1 0.0 2.2e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET40412.1 - 8.3e-09 35.5 0.0 2.5e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AET40412.1 - 0.0014 18.7 0.1 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AET40412.1 - 0.018 13.9 0.0 0.046 12.6 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 AET40412.1 - 0.026 14.2 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2420 PF10336.4 AET40413.1 - 1.5e-34 117.9 1.6 2.5e-34 117.2 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) DUF667 PF05018.8 AET40413.1 - 0.029 13.5 0.1 0.048 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF667) Adap_comp_sub PF00928.16 AET40415.1 - 1.3e-09 37.5 0.3 2.4e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AET40415.1 - 5.1e-06 26.2 0.8 1e-05 25.2 0.6 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3813 PF12758.2 AET40415.1 - 3.4 7.8 7.0 1 9.5 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Proteasome PF00227.21 AET40416.1 - 1.2e-25 89.9 0.1 1.4e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit PDEase_II PF02112.10 AET40417.1 - 1.4e-60 204.9 0.2 2.2e-60 204.3 0.2 1.3 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 AET40417.1 - 9.6e-10 38.3 0.1 1.3e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2638 PF10937.3 AET40418.1 - 1.5e-23 83.9 0.0 1.7e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Ribonuc_red_sm PF00268.16 AET40419.1 - 2.5e-120 400.7 1.5 3.2e-120 400.3 1.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain STN1_2 PF09170.5 AET40419.1 - 0.039 13.7 0.1 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Vfa1 PF08432.5 AET40419.1 - 9 6.2 9.5 36 4.2 5.7 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Thi4 PF01946.12 AET40420.1 - 7.7e-95 316.3 0.2 9.5e-95 316.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 AET40420.1 - 9.6e-09 34.5 1.4 5.2e-08 32.1 0.4 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AET40420.1 - 6.7e-07 29.2 0.5 4.8e-06 26.4 0.2 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AET40420.1 - 1e-05 25.3 0.1 7.7e-05 22.5 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 AET40420.1 - 1.1e-05 24.5 2.3 0.00041 19.3 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 AET40420.1 - 2.7e-05 23.2 0.4 4.6e-05 22.4 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 AET40420.1 - 0.00017 21.5 0.0 0.0014 18.4 0.3 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AET40420.1 - 0.0002 21.4 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AET40420.1 - 0.012 14.0 0.6 0.024 13.1 0.4 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 AET40420.1 - 0.014 14.5 1.5 0.022 13.8 1.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AET40420.1 - 0.018 14.0 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 AET40420.1 - 0.025 13.2 0.3 0.038 12.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 AET40420.1 - 0.031 13.1 0.3 0.086 11.6 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.1 AET40420.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) CENP-Q PF13094.1 AET40421.1 - 0.35 10.8 7.3 0.11 12.5 2.3 2.2 2 2 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit LsmAD PF06741.8 AET40422.1 - 3.8e-28 97.3 0.1 3.8e-28 97.3 0.1 2.6 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.1 AET40422.1 - 4.3e-16 58.5 0.7 9.5e-16 57.5 0.1 2.0 2 0 0 2 2 2 1 Ataxin 2 SM domain RRN7 PF11781.3 AET40423.1 - 1.2e-10 40.6 0.5 2.1e-10 39.9 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 SE PF08491.5 AET40424.1 - 1.4e-112 375.0 0.1 1.9e-112 374.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 AET40424.1 - 1.2e-14 54.1 0.0 3.6e-14 52.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AET40424.1 - 3.8e-08 32.6 0.1 2.5e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AET40424.1 - 6.8e-05 22.8 0.1 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AET40424.1 - 8e-05 22.5 0.2 0.00017 21.5 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AET40424.1 - 0.00012 21.3 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GDI PF00996.13 AET40424.1 - 0.00019 19.9 0.0 0.00051 18.4 0.0 1.6 2 0 0 2 2 2 1 GDP dissociation inhibitor Lycopene_cycl PF05834.7 AET40424.1 - 0.00034 19.6 0.2 0.026 13.4 0.1 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 AET40424.1 - 0.00041 19.3 0.3 0.0007 18.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AET40424.1 - 0.00052 19.2 0.9 0.0029 16.7 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AET40424.1 - 0.00058 20.2 1.4 0.00087 19.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 AET40424.1 - 0.0013 18.4 0.2 0.0021 17.7 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AET40424.1 - 0.0085 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 AET40424.1 - 0.017 13.9 0.7 0.039 12.8 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 AET40424.1 - 0.019 13.4 0.1 0.029 12.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 AET40424.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 AET40424.1 - 0.022 14.1 0.0 0.061 12.7 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Amidinotransf PF02274.12 AET40424.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Amidinotransferase Trp_halogenase PF04820.9 AET40424.1 - 0.069 11.7 1.6 0.23 10.0 0.3 2.2 3 0 0 3 3 3 0 Tryptophan halogenase TrkA_N PF02254.13 AET40424.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Asp_Glu_race PF01177.17 AET40424.1 - 0.12 12.3 0.1 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase ThiF PF00899.16 AET40424.1 - 0.14 12.0 0.2 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 AET40424.1 - 0.18 11.2 0.4 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CBP4 PF07960.6 AET40425.1 - 3.8e-50 168.8 0.8 4.3e-50 168.6 0.6 1.0 1 0 0 1 1 1 1 CBP4 Fez1 PF06818.10 AET40425.1 - 0.022 14.7 5.2 0.029 14.4 3.6 1.1 1 0 0 1 1 1 0 Fez1 DUF919 PF06034.6 AET40425.1 - 0.039 13.5 1.1 0.073 12.6 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DrrA_P4M PF14860.1 AET40425.1 - 0.061 13.0 1.3 0.079 12.7 0.3 1.5 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Clat_adaptor_s PF01217.15 AET40426.1 - 9.9e-55 184.1 0.4 1.3e-54 183.7 0.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Symplekin_C PF12295.3 AET40426.1 - 0.069 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal AA_permease PF00324.16 AET40427.1 - 4.7e-148 493.4 35.5 5.9e-148 493.1 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET40427.1 - 5.9e-42 143.6 36.5 8e-42 143.2 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4389 PF14333.1 AET40427.1 - 0.022 14.4 0.2 0.022 14.4 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) DUF3366 PF11846.3 AET40427.1 - 0.65 9.8 3.3 0.83 9.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) SET PF00856.23 AET40428.1 - 6.5e-09 36.3 0.0 7.2e-06 26.3 0.0 3.1 2 1 0 2 2 2 2 SET domain MFS_1 PF07690.11 AET40429.1 - 1.3e-29 103.0 23.6 1.1e-28 100.0 16.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AET40429.1 - 6.3e-29 100.8 27.2 9e-29 100.3 18.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Ribosomal_L4 PF00573.17 AET40430.1 - 6.2e-47 159.4 1.0 9.9e-47 158.8 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 AET40430.1 - 7.8e-31 105.7 4.1 3.1e-30 103.8 0.7 2.6 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain Methyltransf_31 PF13847.1 AET40431.1 - 1.9e-13 50.2 0.0 3.9e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AET40431.1 - 5.9e-12 45.3 0.0 1.4e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 AET40431.1 - 2.5e-11 44.1 0.0 4.4e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET40431.1 - 9.6e-10 38.5 0.0 2.4e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AET40431.1 - 1.5e-08 35.0 0.0 6.5e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AET40431.1 - 2.3e-07 30.6 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 AET40431.1 - 7.4e-07 28.1 0.1 9.8e-07 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 AET40431.1 - 9.9e-07 28.2 0.6 2.7e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AET40431.1 - 6.5e-06 26.4 0.0 2.3e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AET40431.1 - 8.4e-06 25.0 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.11 AET40431.1 - 4.5e-05 22.5 0.0 5.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 AET40431.1 - 7.4e-05 23.1 0.0 0.0003 21.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 AET40431.1 - 0.00017 21.6 0.0 0.00077 19.4 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 AET40431.1 - 0.00024 20.6 0.1 0.00037 19.9 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 AET40431.1 - 0.0048 16.4 0.1 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 AET40431.1 - 0.01 14.9 0.4 0.031 13.3 0.1 1.8 1 1 1 2 2 2 0 Putative methyltransferase TehB PF03848.9 AET40431.1 - 0.011 14.8 0.1 0.019 14.1 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 AET40431.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 AET40431.1 - 0.05 14.4 0.0 0.097 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 AET40431.1 - 0.062 12.5 0.2 0.12 11.6 0.1 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 UPF0020 PF01170.13 AET40431.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.7 AET40432.1 - 9.1e-43 146.5 0.0 1.2e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 AET40432.1 - 0.00013 21.4 0.0 0.00036 19.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AET40432.1 - 0.00017 21.2 0.1 0.00044 19.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AET40432.1 - 0.00071 18.7 0.1 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 AET40432.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 AET40432.1 - 0.019 15.5 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 AET40432.1 - 0.034 13.6 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 AET40432.1 - 0.082 12.4 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 AET40432.1 - 0.11 12.9 0.0 0.34 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Sld5 PF05916.6 AET40433.1 - 1.4e-09 38.2 0.1 2.1e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein PIF1 PF05970.9 AET40433.1 - 0.016 14.1 0.0 0.019 13.9 0.0 1.2 1 1 0 1 1 1 0 PIF1-like helicase Chordopox_A30L PF06015.7 AET40434.1 - 0.05 13.2 0.2 1.4 8.5 0.0 2.8 2 0 0 2 2 2 0 Chordopoxvirus A30L protein PNPOx_C PF10590.4 AET40435.1 - 3.3e-19 68.0 1.1 7.7e-19 66.9 0.8 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 AET40435.1 - 5.8e-16 58.2 0.0 8.4e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 AET40435.1 - 0.0011 19.2 0.1 0.0029 17.8 0.1 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CRCB PF02537.10 AET40436.1 - 1.7e-26 92.4 14.5 7.9e-19 67.6 3.3 2.6 2 1 0 2 2 2 2 CrcB-like protein DASH_Dad1 PF08649.5 AET40437.1 - 1e-28 98.8 1.3 1.4e-28 98.3 0.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 Mso1_Sec1_bdg PF14475.1 AET40438.1 - 3.5e-21 74.3 0.1 6.7e-21 73.4 0.1 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Hydantoinase_B PF02538.9 AET40439.1 - 9.2e-213 707.2 0.3 1.3e-212 706.6 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 AET40439.1 - 5.7e-93 311.1 0.1 1.1e-92 310.2 0.1 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 AET40439.1 - 1.9e-56 190.3 0.7 2.2e-54 183.6 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Not1 PF04054.10 AET40440.1 - 6.9e-141 469.5 2.7 6.9e-141 469.5 1.9 3.6 3 1 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 AET40440.1 - 1e-41 142.0 4.9 1e-41 142.0 3.4 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) OmpH PF03938.9 AET40440.1 - 3.2e-05 23.9 12.0 3.2e-05 23.9 8.3 3.0 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Gti1_Pac2 PF09729.4 AET40440.1 - 1.5 8.6 6.5 4.7 7.0 1.0 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family FAM222A PF15258.1 AET40440.1 - 4.2 6.4 38.7 0.29 10.3 12.9 2.2 2 0 0 2 2 2 0 Protein family of FAM222A CDC50 PF03381.10 AET40441.1 - 4e-99 331.2 2.1 4.8e-99 331.0 1.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family UQ_con PF00179.21 AET40442.1 - 4.3e-43 146.0 0.0 5.4e-43 145.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 AET40442.1 - 1.4e-25 88.6 0.7 2.2e-25 87.9 0.5 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 AET40442.1 - 0.00031 20.4 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AET40442.1 - 0.037 13.9 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain UBA_2 PF08587.6 AET40442.1 - 0.038 14.1 0.1 0.074 13.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) UBA PF00627.26 AET40442.1 - 0.096 12.5 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 UBA/TS-N domain MutS_V PF00488.16 AET40443.1 - 1.3e-81 273.4 0.3 3.4e-81 272.1 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 AET40443.1 - 7.1e-39 133.7 1.3 1.6e-38 132.5 0.9 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AET40443.1 - 9.3e-28 96.5 0.2 2e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 AET40443.1 - 5.7e-10 39.2 0.3 5.7e-10 39.2 0.2 2.9 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 AET40443.1 - 4.1e-08 33.3 0.3 3.7e-07 30.2 0.0 2.9 2 0 0 2 2 2 1 MutS domain II AF0941-like PF14591.1 AET40443.1 - 0.06 13.4 0.1 0.06 13.4 0.1 4.0 4 0 0 4 4 4 0 AF0941-like YjgP_YjgQ PF03739.9 AET40443.1 - 0.65 8.6 5.8 0.06 12.0 0.1 2.0 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family NPV_P10 PF05531.7 AET40443.1 - 6.1 7.1 8.3 14 6.0 0.1 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.20 AET40444.1 - 2e-73 246.7 0.0 5.3e-73 245.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40444.1 - 6.7e-31 107.2 0.0 5.7e-30 104.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40444.1 - 4.9e-05 22.4 0.1 0.0019 17.2 0.0 2.5 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 AET40444.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET40444.1 - 0.28 10.8 0.0 11 5.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Trm112p PF03966.11 AET40445.1 - 1.1e-18 67.2 0.1 2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Trm112p-like protein Thiolase_N PF00108.18 AET40446.1 - 3e-104 347.6 3.6 3.9e-104 347.3 2.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AET40446.1 - 1.6e-44 150.2 0.3 1.6e-44 150.2 0.2 2.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 AET40446.1 - 0.00011 21.7 4.0 0.00018 21.0 2.3 1.8 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 AET40446.1 - 0.052 13.2 0.3 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pkinase PF00069.20 AET40447.1 - 1.8e-48 164.9 0.1 1.9e-42 145.2 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AET40447.1 - 6.8e-21 74.4 0.1 7.6e-19 67.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AET40447.1 - 7e-08 31.7 0.0 2.8e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AET40447.1 - 0.033 13.2 0.1 0.055 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET40447.1 - 0.15 11.7 1.6 0.17 11.6 0.2 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 AET40447.1 - 0.22 11.0 2.4 0.43 10.1 1.6 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase p450 PF00067.17 AET40448.1 - 4.3e-95 318.9 0.0 5e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 AET40450.1 - 7e-26 91.3 0.0 5.7e-17 62.2 0.0 3.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AET40450.1 - 1.6e-10 41.2 0.0 1.9e-09 37.8 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AET40450.1 - 4.1e-06 27.0 0.1 0.01 15.9 0.1 3.8 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HTH_psq PF05225.11 AET40451.1 - 0.0077 15.7 0.1 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DUF455 PF04305.9 AET40451.1 - 0.01 15.0 0.2 0.023 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Sigma70_ner PF04546.8 AET40451.1 - 0.03 13.9 0.7 0.061 12.9 0.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DEAD PF00270.24 AET40452.1 - 6.8e-35 120.0 0.3 1.8e-34 118.6 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET40452.1 - 8e-24 83.3 0.0 1.6e-22 79.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET40452.1 - 1.1e-05 25.3 0.1 2.8e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 AET40452.1 - 0.03 13.3 0.1 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_S9 PF00380.14 AET40454.1 - 1.7e-39 134.8 0.6 1.9e-39 134.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glyco_trans_1_3 PF13528.1 AET40454.1 - 0.084 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Ribosomal_L13e PF01294.13 AET40455.1 - 6.6e-69 230.9 5.4 8.8e-69 230.5 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_60s PF00428.14 AET40456.1 - 6e-21 74.6 10.7 7.4e-21 74.3 7.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein zf-C3HC4_2 PF13923.1 AET40457.1 - 1.4 8.9 8.6 7.5 6.6 6.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPP_enzyme_N PF02776.13 AET40458.1 - 3.5e-27 94.9 0.0 5.3e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AET40458.1 - 3e-26 91.8 0.0 5.8e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AET40458.1 - 3.1e-13 49.5 0.0 9.6e-13 47.9 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.20 AET40459.1 - 2.5e-60 203.8 0.0 3.5e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40459.1 - 1.2e-25 90.1 0.0 1.8e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AET40459.1 - 0.014 15.1 0.0 0.041 13.5 0.0 1.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 AET40459.1 - 0.026 14.1 0.1 0.026 14.1 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase RICTOR_M PF14666.1 AET40459.1 - 0.061 12.3 0.4 0.12 11.3 0.3 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain DRMBL PF07522.9 AET40460.1 - 4.7e-24 84.5 1.1 1e-23 83.4 0.8 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 AET40460.1 - 1.9e-07 30.8 0.0 4e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AET40460.1 - 0.034 13.8 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily GATA PF00320.22 AET40461.1 - 3.2e-14 51.9 3.3 6.2e-14 51.0 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger Mem_trans PF03547.13 AET40461.1 - 0.41 8.9 5.7 0.65 8.2 3.9 1.3 1 0 0 1 1 1 0 Membrane transport protein Serinc PF03348.10 AET40461.1 - 7.3 5.1 18.1 12 4.5 12.6 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLTH PF10607.4 AET40462.1 - 3.4e-23 81.9 3.6 3.4e-23 81.9 2.5 1.7 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DUF3800 PF12686.2 AET40462.1 - 0.25 10.9 2.6 0.26 10.8 1.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3800) Meiotic_rec114 PF03525.9 AET40465.1 - 1.3e-19 69.9 0.7 1.3e-19 69.9 0.5 1.4 1 1 0 1 1 1 1 Meiotic recombination protein rec114 C6 PF01681.12 AET40465.1 - 0.27 11.3 2.4 0.34 10.9 0.5 2.0 1 1 1 2 2 2 0 C6 domain DUF814 PF05670.8 AET40466.1 - 5e-20 71.1 0.4 1.1e-19 70.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Glyco_hydro_17 PF00332.13 AET40466.1 - 0.021 13.8 0.1 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 CAF1C_H4-bd PF12265.3 AET40467.1 - 5.5e-17 61.4 0.3 1.3e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 AET40467.1 - 1.3e-16 59.7 10.9 2.3e-06 27.2 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Ammonium_transp PF00909.16 AET40467.1 - 0.13 10.7 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family RIC1 PF07064.8 AET40468.1 - 5.3e-10 39.1 0.2 4.3e-09 36.2 0.1 2.4 1 1 0 1 1 1 1 RIC1 COX6B PF02297.12 AET40469.1 - 2.6e-21 75.4 4.0 3e-21 75.2 2.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Somatostatin PF03002.10 AET40469.1 - 0.043 13.4 2.1 0.09 12.4 1.4 1.6 1 0 0 1 1 1 0 Somatostatin/Cortistatin family UCR_hinge PF02320.11 AET40469.1 - 0.1 12.5 0.2 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein APOBEC_C PF05240.9 AET40469.1 - 0.21 11.0 1.4 0.31 10.4 1.0 1.4 1 1 0 1 1 1 0 APOBEC-like C-terminal domain UPF0203 PF05254.7 AET40469.1 - 0.88 9.4 4.4 0.58 10.0 1.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) HATPase_c_3 PF13589.1 AET40470.1 - 5.4e-11 42.2 0.7 4.4e-10 39.3 0.0 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AET40470.1 - 2.8e-07 30.2 0.0 6.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 AET40470.1 - 4e-07 29.5 0.0 1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Nramp PF01566.13 AET40472.1 - 2.8e-96 322.4 19.0 4e-96 321.9 13.2 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF202 PF02656.10 AET40472.1 - 7.2 6.9 8.4 3.4 7.9 0.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Bromodomain PF00439.20 AET40473.1 - 0.00037 20.3 0.0 0.0017 18.2 0.0 2.1 2 0 0 2 2 2 1 Bromodomain HA2 PF04408.18 AET40474.1 - 8.4e-26 89.9 0.0 3.8e-25 87.8 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AET40474.1 - 5.8e-14 51.7 0.0 2.5e-13 49.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 AET40474.1 - 1.5e-12 47.3 0.1 6.8e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 AET40474.1 - 1.9e-08 33.9 0.5 5.2e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AET40474.1 - 8.3e-05 22.7 0.2 0.00063 19.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AET40474.1 - 0.0013 17.6 0.0 0.0034 16.3 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 AET40474.1 - 0.006 15.7 5.5 0.0061 15.7 0.0 3.0 4 0 0 4 4 4 1 KaiC UPF0079 PF02367.12 AET40474.1 - 0.076 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 AET40474.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 AET40474.1 - 0.14 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MOZ_SAS PF01853.13 AET40475.1 - 1.1e-61 207.4 0.2 1.5e-61 206.9 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family DUF4129 PF13559.1 AET40476.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) MIF4G_like PF09088.6 AET40477.1 - 8.8e-59 198.1 2.5 9.6e-59 198.0 0.6 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 AET40477.1 - 2.2e-52 177.7 4.4 3.8e-52 177.0 3.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 AET40477.1 - 9.2e-14 51.3 4.3 1.1e-13 51.0 1.2 2.4 2 0 0 2 2 2 1 MIF4G domain Pkr1 PF08636.5 AET40478.1 - 3.2e-31 107.2 7.9 3.9e-31 106.9 5.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FA_desaturase PF00487.19 AET40478.1 - 0.021 14.2 0.5 0.023 14.1 0.3 1.1 1 0 0 1 1 1 0 Fatty acid desaturase FA_hydroxylase PF04116.8 AET40478.1 - 0.043 14.2 0.1 0.05 13.9 0.1 1.2 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily DUF2206 PF09971.4 AET40478.1 - 0.043 12.6 2.1 0.054 12.3 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) YesK PF14150.1 AET40478.1 - 0.98 9.5 4.5 4.6 7.4 3.1 1.8 1 1 0 1 1 1 0 YesK-like protein DUF2076 PF09849.4 AET40479.1 - 0.11 12.5 3.7 0.12 12.3 2.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SSP160 PF06933.6 AET40479.1 - 0.2 9.5 22.2 0.22 9.4 15.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAM104 PF15434.1 AET40479.1 - 0.35 11.0 3.7 0.43 10.8 2.6 1.2 1 0 0 1 1 1 0 Family 104 Macoilin PF09726.4 AET40479.1 - 6.1 5.0 6.1 6.4 4.9 4.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.4 AET40479.1 - 6.9 5.0 5.8 7.7 4.9 4.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Bacteriocin_IIc PF10439.4 AET40479.1 - 8 6.6 11.0 28 4.9 7.6 1.9 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF515 PF04415.7 AET40479.1 - 9.1 4.3 9.8 9.1 4.3 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Ribosomal_L15e PF00827.12 AET40480.1 - 1e-89 299.1 15.6 1.2e-89 298.9 10.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 AICARFT_IMPCHas PF01808.13 AET40481.1 - 1.7e-120 401.8 0.0 2.4e-120 401.3 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 AET40481.1 - 9.6e-24 83.1 0.8 3.5e-23 81.3 0.0 2.3 3 0 0 3 3 3 1 MGS-like domain zf-C3HC4_3 PF13920.1 AET40482.1 - 1e-07 31.5 11.4 1e-07 31.5 7.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Cation_ATPase_C PF00689.16 AET40482.1 - 0.1 12.1 5.7 0.031 13.7 1.3 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus zf-C3HC4_2 PF13923.1 AET40482.1 - 9.3 6.3 18.5 5 7.2 10.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Aminotran_1_2 PF00155.16 AET40483.1 - 5.1e-73 246.0 0.0 6.1e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin PF00804.20 AET40484.1 - 1.8e-18 66.6 0.6 1.8e-18 66.6 0.4 2.9 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 AET40484.1 - 8.7e-18 63.7 3.6 8.7e-18 63.7 2.5 2.2 2 0 0 2 2 2 1 SNARE domain Sed5p PF11416.3 AET40484.1 - 4.6e-11 41.9 1.4 7.8e-11 41.2 0.1 2.1 2 0 0 2 2 2 1 Integral membrane protein Sed5p MCPsignal PF00015.16 AET40484.1 - 0.00079 19.0 0.2 0.00079 19.0 0.1 3.0 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-6_N PF09177.6 AET40484.1 - 0.024 15.0 5.9 1.3 9.4 0.1 3.5 2 2 1 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 AET40484.1 - 0.037 13.8 8.6 0.38 10.5 0.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) V-SNARE PF05008.10 AET40484.1 - 0.057 13.5 3.7 0.1 12.7 0.9 2.6 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2937 PF11157.3 AET40484.1 - 0.15 11.4 2.1 2.5 7.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2421 PF10334.4 AET40484.1 - 0.34 10.4 4.2 2.8 7.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2421) Glutaredoxin2_C PF04399.8 AET40484.1 - 0.55 9.8 6.5 0.93 9.0 0.3 3.3 4 1 0 4 4 4 0 Glutaredoxin 2, C terminal domain Reo_sigmaC PF04582.7 AET40484.1 - 0.74 8.9 3.8 8.1 5.5 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF2458 PF10454.4 AET40484.1 - 0.95 9.3 6.3 0.19 11.5 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) DUF16 PF01519.11 AET40484.1 - 2.1 8.5 10.1 1.1 9.5 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 Filo_VP35 PF02097.10 AET40484.1 - 2.2 7.4 5.4 0.72 8.9 0.3 2.3 2 1 1 3 3 3 0 Filoviridae VP35 IncA PF04156.9 AET40484.1 - 8 5.9 15.6 0.26 10.8 3.3 2.8 2 1 0 2 2 2 0 IncA protein zf-C4H2 PF10146.4 AET40484.1 - 8.2 6.3 8.8 0.22 11.4 0.8 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein Snf7 PF03357.16 AET40485.1 - 5.3e-52 175.6 12.4 5.3e-52 175.6 8.6 1.8 2 0 0 2 2 2 1 Snf7 Snapin_Pallidin PF14712.1 AET40485.1 - 0.15 12.4 9.5 0.19 12.0 4.5 2.5 1 1 0 2 2 2 0 Snapin/Pallidin CHASE3 PF05227.8 AET40485.1 - 0.16 11.6 7.2 0.36 10.4 5.0 1.7 1 1 0 1 1 1 0 CHASE3 domain Cupin_8 PF13621.1 AET40485.1 - 0.46 9.9 1.9 0.63 9.4 1.2 1.4 1 1 0 1 1 1 0 Cupin-like domain Prefoldin PF02996.12 AET40485.1 - 1.3 8.6 8.9 0.72 9.5 0.5 2.7 2 1 0 2 2 2 0 Prefoldin subunit PspA_IM30 PF04012.7 AET40485.1 - 1.5 8.1 17.8 0.098 12.0 7.6 2.4 2 1 0 2 2 2 0 PspA/IM30 family TBPIP PF07106.8 AET40485.1 - 6.8 6.2 15.2 0.65 9.5 2.0 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 AET40486.1 - 0.0029 17.3 0.5 0.0061 16.2 0.4 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF1640 PF07798.6 AET40486.1 - 0.024 14.7 0.6 0.047 13.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Nnf1 PF03980.9 AET40486.1 - 0.032 14.2 0.6 0.032 14.2 0.4 2.3 4 0 0 4 4 4 0 Nnf1 DivIC PF04977.10 AET40486.1 - 0.14 11.6 1.6 0.28 10.6 1.1 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 AET40486.1 - 0.28 11.0 3.1 0.67 9.8 2.1 1.6 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 AET40486.1 - 0.58 10.1 2.6 0.53 10.2 0.7 1.7 2 0 0 2 2 2 0 bZIP transcription factor Sdh_cyt PF01127.17 AET40487.1 - 4.9e-26 90.9 1.7 6.2e-26 90.6 1.2 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pkinase PF00069.20 AET40488.1 - 4.7e-75 252.0 0.0 6.6e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40488.1 - 8.4e-34 116.8 0.0 1.1e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40488.1 - 0.00017 20.6 0.0 0.00035 19.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AET40488.1 - 0.018 14.7 0.0 0.043 13.5 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Hsk3 PF08227.6 AET40489.1 - 1.8e-18 66.4 4.3 2.5e-18 65.9 3.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Transposase_24 PF03004.9 AET40489.1 - 0.014 15.2 0.1 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) LPP20 PF02169.11 AET40489.1 - 0.034 14.2 0.7 0.04 14.0 0.5 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein Bap31 PF05529.7 AET40489.1 - 0.084 12.3 2.6 0.094 12.1 1.8 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Clathrin_bdg PF15045.1 AET40489.1 - 0.092 12.2 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking FTA4 PF13093.1 AET40489.1 - 0.097 12.0 3.6 0.13 11.7 2.2 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FliD_N PF02465.13 AET40489.1 - 0.1 12.9 2.0 0.11 12.8 1.4 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus UPF0449 PF15136.1 AET40489.1 - 0.19 11.9 1.1 0.22 11.7 0.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 CorA PF01544.13 AET40489.1 - 0.23 10.4 1.3 0.26 10.2 0.9 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Spc24 PF08286.6 AET40490.1 - 3.7e-21 75.0 2.9 3.7e-21 75.0 2.0 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Ribosomal_S2 PF00318.15 AET40490.1 - 0.087 12.0 1.8 0.22 10.6 1.2 1.7 1 1 0 1 1 1 0 Ribosomal protein S2 Seryl_tRNA_N PF02403.17 AET40490.1 - 0.37 10.8 14.4 5.7 7.0 8.2 2.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.13 AET40490.1 - 0.39 9.6 11.6 0.56 9.1 8.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Peptidase_S64 PF08192.6 AET40490.1 - 0.57 8.4 8.0 0.65 8.2 5.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Exonuc_VII_L PF02601.10 AET40490.1 - 1.9 7.6 11.6 2.4 7.2 8.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TBPIP PF07106.8 AET40490.1 - 2.1 7.8 11.9 3.1 7.3 8.2 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 AET40490.1 - 2.2 8.0 20.2 19 5.0 13.1 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GLE1 PF07817.8 AET40490.1 - 2.7 6.8 9.7 0.72 8.7 3.6 1.8 1 1 1 2 2 2 0 GLE1-like protein DUF3103 PF11301.3 AET40490.1 - 3.1 6.4 7.8 2.9 6.4 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3103) DUF342 PF03961.8 AET40490.1 - 4 5.7 7.7 5 5.4 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 AET40490.1 - 9.8 6.6 10.3 9.9 6.6 2.8 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) L31 PF09784.4 AET40491.1 - 3.8e-41 139.3 3.8 6.7e-41 138.5 2.6 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cmc1 PF08583.5 AET40492.1 - 3.6e-20 71.4 2.8 4.9e-20 71.0 1.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Adaptin_N PF01602.15 AET40493.1 - 7.9e-117 390.7 14.9 1.1e-116 390.3 10.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 AET40493.1 - 3.2e-16 59.6 2.4 3.2e-16 59.6 1.6 2.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AET40493.1 - 1.3e-09 38.1 3.5 1.9e-05 24.8 0.0 5.4 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.17 AET40493.1 - 5.6e-08 32.2 3.0 0.0087 16.0 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 AET40493.1 - 0.00058 20.2 2.1 3.6 8.2 0.0 5.5 6 0 0 6 6 6 1 HEAT-like repeat WD40 PF00400.27 AET40494.1 - 3.2e-56 185.3 16.2 1e-08 34.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AET40494.1 - 9.7e-06 23.9 7.7 0.0015 16.7 0.2 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.6 AET40494.1 - 3.4e-05 23.6 0.2 0.0042 16.8 0.0 2.8 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 AET40494.1 - 0.011 14.5 0.1 4.4 5.9 0.2 3.0 1 1 1 3 3 3 0 Nup133 N terminal like Peptidase_M3 PF01432.15 AET40495.1 - 2.5e-131 438.8 0.0 3.9e-131 438.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 AET40495.1 - 0.18 11.1 0.1 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Arc_PepC PF06819.6 AET40495.1 - 2.6 8.0 5.9 30 4.5 0.1 3.0 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain DUF159 PF02586.9 AET40496.1 - 2e-56 190.8 0.1 2.7e-56 190.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 DKCLD PF08068.7 AET40496.1 - 0.00034 20.4 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 DKCLD (NUC011) domain Lipocalin PF00061.18 AET40496.1 - 0.016 15.2 0.2 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family MxiM PF11441.3 AET40496.1 - 0.12 12.4 0.1 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Pilot protein MxiM Mur_ligase_M PF08245.7 AET40497.1 - 9.2e-09 35.6 0.0 2.7e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain GCR1_C PF12550.3 AET40498.1 - 1.3e-27 95.4 0.9 3.7e-27 93.9 0.6 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Seryl_tRNA_N PF02403.17 AET40498.1 - 0.015 15.2 3.5 0.047 13.7 2.4 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4061 PF13270.1 AET40498.1 - 0.052 13.6 2.4 0.19 11.8 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) DUF342 PF03961.8 AET40498.1 - 0.11 10.8 3.2 0.16 10.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DASH_Dad3 PF08656.5 AET40498.1 - 1.7 8.4 7.6 21 4.8 3.4 3.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 She2p PF11435.3 AET40499.1 - 1.9e-89 298.4 6.4 2.8e-89 297.9 4.5 1.2 1 0 0 1 1 1 1 RNA binding protein She2p Cyclin PF08613.6 AET40499.1 - 0.066 13.6 0.4 0.11 12.9 0.3 1.3 1 0 0 1 1 1 0 Cyclin Myosin_head PF00063.16 AET40500.1 - 4.4e-223 742.2 3.8 6.8e-223 741.6 2.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 AET40500.1 - 3.6e-46 156.9 0.0 3.3e-45 153.8 0.0 2.2 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 AET40500.1 - 2.1e-12 46.2 0.0 4e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AET40500.1 - 4.4e-09 35.7 0.0 8.6e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AET40500.1 - 1.7e-05 24.1 0.0 3.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 AET40500.1 - 0.0054 16.8 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AET40500.1 - 0.025 13.6 0.4 0.076 12.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 AET40500.1 - 0.036 14.8 0.0 0.19 12.5 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AET40500.1 - 0.046 14.0 0.0 0.62 10.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AET40500.1 - 0.072 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 AET40500.1 - 0.074 12.8 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Hpr_kinase_C PF07475.7 AET40500.1 - 0.095 12.0 0.1 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.21 AET40500.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IQ PF00612.22 AET40500.1 - 6.7 6.6 14.5 1.1 9.1 4.1 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif TPP_enzyme_N PF02776.13 AET40501.1 - 1.7e-58 196.8 0.1 2e-57 193.4 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AET40501.1 - 3e-48 163.2 0.4 1.3e-46 158.0 0.0 2.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AET40501.1 - 1.7e-37 128.2 3.1 2.3e-37 127.8 0.8 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 AET40501.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit POR_N PF01855.14 AET40501.1 - 0.025 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg His_Phos_1 PF00300.17 AET40502.1 - 5.7e-17 62.2 0.0 7.9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_17 PF00332.13 AET40504.1 - 1.2e-05 24.5 0.0 6.2e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 SSP160 PF06933.6 AET40504.1 - 5.9 4.7 23.3 8.7 4.1 16.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mid2 PF04478.7 AET40505.1 - 6.2e-45 152.3 4.5 6.2e-45 152.3 3.1 3.7 2 2 1 4 4 4 1 Mid2 like cell wall stress sensor E1-E2_ATPase PF00122.15 AET40506.1 - 9.3e-75 250.5 0.3 1.9e-74 249.5 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AET40506.1 - 4.3e-46 156.7 0.5 4.3e-46 156.7 0.3 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AET40506.1 - 4.4e-33 115.5 0.1 7.2e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AET40506.1 - 3e-18 65.5 0.0 6e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AET40506.1 - 1.9e-16 60.8 0.0 4.6e-16 59.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AET40506.1 - 2.5e-13 49.2 0.0 5.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AET40506.1 - 7.3e-06 25.7 1.8 0.00013 21.6 0.6 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.2 AET40506.1 - 0.013 15.4 0.9 0.013 15.4 0.6 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) Sua5_yciO_yrdC PF01300.13 AET40507.1 - 1.2e-51 174.4 0.0 4.3e-51 172.6 0.0 1.7 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 AET40507.1 - 2.1e-28 98.9 0.0 3e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding FTR1 PF03239.9 AET40508.1 - 1.6e-90 303.1 10.7 1.9e-90 302.9 7.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4293 PF14126.1 AET40508.1 - 0.28 11.1 11.3 0.92 9.4 1.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Ferric_reduct PF01794.14 AET40508.1 - 1.5 8.8 6.2 0.58 10.2 0.6 2.5 2 1 0 2 2 2 0 Ferric reductase like transmembrane component Bax1-I PF01027.15 AET40508.1 - 5.5 6.5 22.4 0.28 10.7 4.9 3.1 3 0 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 Copper-fist PF00649.13 AET40509.1 - 1e-21 75.8 1.0 1e-21 75.8 0.7 2.6 1 1 1 2 2 2 1 Copper fist DNA binding domain Ran-binding PF05508.6 AET40510.1 - 1.5e-106 355.6 3.6 2.1e-106 355.2 2.5 1.2 1 0 0 1 1 1 1 RanGTP-binding protein CFIA_Pcf11 PF11526.3 AET40510.1 - 0.013 15.5 0.7 0.033 14.3 0.5 1.6 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 SNF2_N PF00176.18 AET40511.1 - 6.6e-69 231.9 0.0 9.7e-69 231.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 AET40511.1 - 4.7e-49 166.8 0.0 1.5e-48 165.1 0.0 1.8 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 AET40511.1 - 9.6e-13 47.8 0.0 4.8e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AET40511.1 - 1.6e-08 33.7 0.0 6.2e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 AET40511.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CP_ATPgrasp_1 PF04174.8 AET40513.1 - 0.049 12.2 0.0 0.055 12.0 0.0 1.1 1 0 0 1 1 1 0 A circularly permuted ATPgrasp POM121 PF15229.1 AET40514.1 - 0.2 11.0 6.3 0.24 10.7 1.7 1.9 1 1 1 2 2 2 0 POM121 family Zn_clus PF00172.13 AET40515.1 - 0.00097 19.0 11.9 0.0016 18.2 1.7 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PepSY_TM_2 PF13703.1 AET40516.1 - 0.028 14.5 1.2 0.028 14.5 0.8 2.1 2 0 0 2 2 2 0 PepSY-associated TM helix DctQ PF04290.7 AET40516.1 - 0.42 10.3 7.6 0.25 11.0 1.7 2.6 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component RNA_pol_I_TF PF04090.7 AET40517.1 - 0.013 14.7 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor Blo-t-5 PF11642.3 AET40517.1 - 0.018 14.7 0.1 0.049 13.3 0.1 1.7 1 0 0 1 1 1 0 Mite allergen Blo t 5 DUF1447 PF07288.6 AET40517.1 - 0.089 12.5 0.3 0.28 10.9 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1447) SlyX PF04102.7 AET40517.1 - 0.67 10.3 3.2 1 9.7 0.4 2.5 3 0 0 3 3 3 0 SlyX Rad21_Rec8_N PF04825.8 AET40518.1 - 3.7e-15 55.8 0.0 8.8e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Bromodomain PF00439.20 AET40519.1 - 6.2e-36 122.1 8.4 2.1e-23 82.0 1.0 2.5 2 0 0 2 2 2 2 Bromodomain DUF1810 PF08837.6 AET40519.1 - 0.077 12.5 0.1 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1810) LAMTOR PF15454.1 AET40520.1 - 6.5e-12 45.5 3.9 8.8e-12 45.1 2.7 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Ribosomal_L50 PF10501.4 AET40521.1 - 3.2e-22 78.5 0.4 1e-21 76.9 0.1 1.9 2 0 0 2 2 2 1 Ribosomal subunit 39S DUF4588 PF15251.1 AET40521.1 - 0.085 12.8 0.4 0.16 11.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) DUF4042 PF13251.1 AET40523.1 - 0.086 12.2 0.2 0.87 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) Oxysterol_BP PF01237.13 AET40524.1 - 3.1e-88 295.6 0.0 4e-88 295.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein eIF2A PF08662.6 AET40525.1 - 5.4e-74 248.1 0.0 1.7e-72 243.2 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 AET40525.1 - 0.01 15.7 0.3 12 5.9 0.1 4.4 3 1 0 3 3 3 0 WD domain, G-beta repeat Pkinase PF00069.20 AET40527.1 - 1.5e-53 181.5 0.0 2e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40527.1 - 2.2e-32 112.1 0.0 3.1e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40527.1 - 2.4e-09 36.5 0.0 1.7e-08 33.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 AET40527.1 - 0.0021 17.8 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AET40527.1 - 0.0074 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PhaP_Bmeg PF09602.5 AET40527.1 - 0.057 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) IlvC PF01450.14 AET40529.1 - 4.3e-48 162.9 0.0 1.1e-47 161.6 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 AET40529.1 - 2e-45 154.1 0.0 2.9e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 AET40529.1 - 0.0036 17.1 0.0 0.0088 15.8 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AET40529.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AhpC-TSA PF00578.16 AET40530.1 - 3.5e-29 101.0 0.0 4.4e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AET40530.1 - 2.1e-09 37.0 0.0 2.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 AET40530.1 - 2.9e-06 26.8 0.0 5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Transaldolase PF00923.14 AET40531.1 - 1.4e-99 332.8 0.1 1.6e-99 332.6 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Zn_clus PF00172.13 AET40532.1 - 6.7e-09 35.5 10.2 6.7e-09 35.5 7.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 AET40532.1 - 0.17 11.4 1.5 0.24 11.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DUF2439 PF10382.4 AET40533.1 - 5.7e-25 87.3 0.3 9.8e-25 86.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Rxt3 PF08642.5 AET40534.1 - 0.11 12.7 2.2 0.21 11.8 0.0 2.5 3 1 0 3 3 3 0 Histone deacetylation protein Rxt3 F-box-like PF12937.2 AET40535.1 - 0.00045 19.8 0.4 0.038 13.7 0.0 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 AET40535.1 - 0.0077 15.8 1.0 0.0077 15.8 0.7 4.8 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AET40535.1 - 0.0097 15.6 4.1 0.057 13.1 0.7 3.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 AET40535.1 - 0.032 14.3 5.8 13 6.5 0.0 5.5 6 0 0 6 6 6 0 Leucine rich repeat F-box PF00646.28 AET40535.1 - 0.056 13.1 0.2 7.2 6.3 0.0 3.0 3 0 0 3 3 3 0 F-box domain LRR_1 PF00560.28 AET40535.1 - 0.092 12.8 8.2 25 5.4 0.0 5.9 4 2 2 6 6 6 0 Leucine Rich Repeat Pkinase PF00069.20 AET40536.1 - 1.3e-74 250.6 0.0 1.7e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40536.1 - 9.5e-34 116.6 0.0 1.5e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40536.1 - 1.9e-06 27.0 0.0 3.6e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 AET40536.1 - 7.6e-05 21.8 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET40536.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CN_hydrolase PF00795.17 AET40537.1 - 2.6e-28 98.6 0.0 3.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ORMDL PF04061.9 AET40538.1 - 9.9e-57 190.2 5.1 1.2e-56 190.0 3.6 1.1 1 0 0 1 1 1 1 ORMDL family ACBP PF00887.14 AET40539.1 - 1.3e-30 104.8 1.3 1.4e-30 104.7 0.9 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 AET40539.1 - 0.019 15.1 0.1 0.36 10.9 0.0 2.0 1 1 0 2 2 2 0 FERM central domain DUF1413 PF07205.6 AET40539.1 - 0.056 12.9 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) GPAT_N PF14829.1 AET40539.1 - 0.08 12.6 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal HEAT PF02985.17 AET40540.1 - 2.6e-16 58.1 20.0 9.7e-05 22.1 0.0 10.6 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 AET40540.1 - 2.9e-13 49.8 14.5 3.6e-06 27.2 0.0 8.8 8 1 1 9 9 9 3 HEAT-like repeat IBN_N PF03810.14 AET40540.1 - 1.7e-11 43.8 1.1 2.2e-10 40.2 0.8 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 AET40540.1 - 2.5e-10 40.5 9.5 0.00067 19.8 0.0 7.3 3 2 4 8 8 8 3 HEAT repeats DUF3385 PF11865.3 AET40540.1 - 0.00057 19.8 3.2 1.9 8.4 0.3 4.9 3 2 1 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.3 AET40540.1 - 0.00064 19.1 8.0 0.14 11.4 0.0 5.0 6 0 0 6 6 6 2 CLASP N terminal Arm PF00514.18 AET40540.1 - 0.0016 18.1 12.5 0.011 15.5 0.1 5.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat PAP2 PF01569.16 AET40541.1 - 5.8e-18 64.8 3.4 5.8e-18 64.8 2.4 1.5 2 0 0 2 2 2 1 PAP2 superfamily 6PF2K PF01591.13 AET40542.1 - 2.8e-62 209.7 1.1 3.9e-62 209.2 0.7 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AET40542.1 - 7.2e-21 74.9 0.0 2.9e-19 69.7 0.0 2.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.5 AET40542.1 - 0.0099 15.1 0.6 0.041 13.0 0.1 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 AET40542.1 - 0.031 14.1 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain KOW PF00467.24 AET40543.1 - 0.00017 21.1 1.5 0.00025 20.6 0.1 1.9 2 0 0 2 2 2 1 KOW motif TIM21 PF08294.6 AET40544.1 - 5.4e-57 191.5 0.7 8.1e-57 190.9 0.1 1.5 2 0 0 2 2 2 1 TIM21 DUF374 PF04028.8 AET40544.1 - 0.033 13.4 1.0 2 7.7 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF374) Glyco_hydro_72 PF03198.9 AET40545.1 - 1.1e-138 461.4 0.6 1.5e-138 461.0 0.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 AET40545.1 - 1e-12 48.3 0.3 2.5e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 X8 domain Glucan_synthase PF02364.10 AET40546.1 - 0 1433.3 0.0 0 1432.6 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 AET40546.1 - 2.9e-39 133.5 0.1 6.8e-39 132.3 0.1 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Ribosomal_L10 PF00466.15 AET40547.1 - 3.9e-27 94.0 0.1 7.6e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 AET40547.1 - 2.4e-17 63.1 2.5 2.4e-17 63.1 1.7 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein Alba PF01918.16 AET40548.1 - 1.6e-05 24.3 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alba tRNA_int_endo PF01974.12 AET40549.1 - 1.1e-13 50.7 0.0 2.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Lambda_Kil PF06301.6 AET40549.1 - 0.057 12.8 0.0 8.7 5.8 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein E1-E2_ATPase PF00122.15 AET40550.1 - 2.5e-61 206.6 2.4 2.5e-61 206.6 1.6 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AET40550.1 - 3.5e-41 140.7 5.7 3.5e-41 140.7 4.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AET40550.1 - 9.5e-24 85.0 0.0 4.6e-23 82.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AET40550.1 - 2.2e-15 56.3 0.1 7e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AET40550.1 - 1.4e-13 51.4 0.0 4.3e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AET40550.1 - 9.6e-11 40.9 0.0 3.1e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AET40550.1 - 2.2e-05 24.1 0.9 0.00021 20.9 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase COG5 PF10392.4 AET40551.1 - 0.00081 19.3 6.8 0.00083 19.3 2.3 2.5 2 1 0 2 2 2 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.4 AET40551.1 - 0.05 13.4 4.3 0.052 13.4 1.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 AET40551.1 - 0.066 12.5 5.2 0.34 10.2 0.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain WD40 PF00400.27 AET40552.1 - 3.2e-18 64.8 3.3 7.8e-08 31.9 0.0 4.1 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 AET40552.1 - 0.0075 16.0 0.1 0.69 9.5 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Rep_fac-A_C PF08646.5 AET40553.1 - 1.5e-59 199.9 1.0 8.5e-56 187.7 0.7 2.7 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 AET40553.1 - 8.8e-21 73.5 1.8 2.9e-10 39.8 0.0 5.1 5 1 0 5 5 5 4 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 AET40553.1 - 0.00054 19.7 0.2 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain WD40 PF00400.27 AET40554.1 - 1.1e-32 110.6 2.3 3.6e-06 26.6 0.5 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 AET40554.1 - 6.7e-05 22.6 0.1 0.01 15.5 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 AET40555.1 - 1.5e-14 53.1 9.6 7.2e-07 28.8 1.5 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AET40555.1 - 0.0015 16.8 0.1 0.0039 15.5 0.0 1.6 2 0 0 2 2 2 1 Cytochrome D1 heme domain Lgl_C PF08596.5 AET40555.1 - 0.011 14.2 0.1 0.23 9.9 0.0 2.2 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal eIF2A PF08662.6 AET40555.1 - 0.069 12.8 0.1 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A EMP24_GP25L PF01105.19 AET40556.1 - 1.2e-45 155.5 1.4 1.4e-45 155.2 1.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2846 PF11008.3 AET40556.1 - 0.042 13.6 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) B-block_TFIIIC PF04182.7 AET40559.1 - 2.3e-17 62.5 0.0 6e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC N6-adenineMlase PF10237.4 AET40560.1 - 7.5e-61 204.5 0.1 1e-60 204.0 0.1 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase DUF4456 PF14644.1 AET40560.1 - 0.039 13.1 2.8 0.066 12.4 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) DUF2514 PF10721.4 AET40560.1 - 0.17 11.5 2.3 0.31 10.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) IncA PF04156.9 AET40560.1 - 2.4 7.7 6.3 3.3 7.2 4.4 1.2 1 0 0 1 1 1 0 IncA protein 3Beta_HSD PF01073.14 AET40561.1 - 2.3e-81 272.5 0.0 2.7e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AET40561.1 - 9.8e-26 90.6 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AET40561.1 - 2.4e-15 56.1 0.0 7e-15 54.6 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 AET40561.1 - 3.9e-10 39.1 0.0 6.3e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AET40561.1 - 5.1e-06 25.5 0.0 1.3e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AET40561.1 - 5.7e-06 26.4 0.0 8.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AET40561.1 - 0.00089 18.5 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 AET40561.1 - 0.0046 16.6 0.0 0.02 14.5 0.0 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 AET40561.1 - 0.0078 16.1 0.0 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Bradykinin PF06753.7 AET40561.1 - 1.5 8.4 4.7 0.24 10.9 0.2 2.0 2 0 0 2 2 2 0 Bradykinin Vps8 PF12816.2 AET40562.1 - 9.8e-57 191.3 4.1 1.1e-55 187.9 3.4 2.3 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 PPR PF01535.15 AET40562.1 - 0.0026 17.6 0.2 3.6 7.7 0.0 4.0 3 0 0 3 3 3 1 PPR repeat zf-C3HC4 PF00097.20 AET40562.1 - 0.0032 17.1 2.3 0.0032 17.1 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET40562.1 - 0.0057 16.3 1.0 0.0057 16.3 0.7 2.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 AET40562.1 - 0.01 15.6 2.3 0.041 13.7 1.6 2.1 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.24 AET40562.1 - 0.026 14.2 1.9 0.092 12.4 1.3 1.9 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 AET40562.1 - 0.82 9.7 5.2 0.5 10.4 1.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AET40562.1 - 4.2 7.5 9.8 2.4 8.3 4.5 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger EF1_GNE PF00736.14 AET40563.1 - 8.9e-31 105.4 1.3 1.7e-30 104.5 0.9 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 AET40563.1 - 7.4e-12 45.1 5.9 7.4e-12 45.1 4.1 2.8 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.1 AET40563.1 - 0.01 15.7 0.1 0.26 11.1 0.0 2.4 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AET40563.1 - 0.052 13.5 4.1 0.2 11.6 0.2 3.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ANAPC15 PF15243.1 AET40563.1 - 0.26 11.3 6.2 0.55 10.3 0.6 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 SNF5 PF04855.7 AET40564.1 - 3.7e-66 223.0 2.4 2.6e-63 213.7 1.7 2.3 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 CHD5 PF04420.9 AET40566.1 - 5.9e-37 126.8 1.4 7.2e-37 126.5 1.0 1.1 1 0 0 1 1 1 1 CHD5-like protein UCH PF00443.24 AET40567.1 - 1.4e-65 221.0 3.2 1.4e-65 221.0 2.2 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AET40567.1 - 5.7e-25 88.3 2.4 1.6e-24 86.8 1.7 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 AET40567.1 - 0.00047 20.4 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Zn-ribbon_8 PF09723.5 AET40567.1 - 0.01 15.7 3.2 0.49 10.3 1.2 2.7 2 0 0 2 2 2 1 Zinc ribbon domain zf-MIZ PF02891.15 AET40567.1 - 0.011 15.2 0.5 0.035 13.6 0.4 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger UPF0270 PF06794.7 AET40567.1 - 0.12 12.1 0.0 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Rubredoxin PF00301.15 AET40567.1 - 0.17 11.7 2.3 0.4 10.5 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin BSD PF03909.12 AET40568.1 - 4.7e-12 45.4 3.2 7.6e-12 44.8 0.0 2.9 3 0 0 3 3 3 1 BSD domain FliT PF05400.8 AET40568.1 - 0.011 16.1 7.8 1.8 8.9 0.3 3.4 3 1 0 3 3 3 0 Flagellar protein FliT Uteroglobin PF01099.12 AET40568.1 - 0.059 13.1 0.4 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Uteroglobin family Glyco_hydro_4C PF11975.3 AET40568.1 - 0.35 10.6 3.0 0.61 9.8 1.7 1.6 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Y_phosphatase2 PF03162.8 AET40569.1 - 3.3e-54 182.6 0.5 4e-54 182.4 0.4 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 AET40569.1 - 0.00061 19.3 0.1 0.00077 19.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Asp_protease PF09668.5 AET40570.1 - 2e-53 179.1 0.1 3.3e-53 178.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 AET40570.1 - 2.8e-11 43.7 0.2 6.2e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 AET40570.1 - 6.1e-07 29.2 0.1 1.6e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 AET40570.1 - 1.3e-06 28.4 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 AET40570.1 - 1.7e-05 24.5 0.0 4.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 AET40570.1 - 3e-05 23.7 0.0 8.1e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_Rpb5_C PF01191.14 AET40570.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain HhH-GPD PF00730.20 AET40571.1 - 1.2e-12 48.0 0.0 1.9e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein IGR PF09597.5 AET40571.1 - 0.14 12.0 0.8 3.9 7.4 0.4 2.4 2 0 0 2 2 2 0 IGR protein motif COX15-CtaA PF02628.10 AET40572.1 - 8.4e-102 340.0 2.3 1.1e-101 339.7 1.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein CD20 PF04103.10 AET40572.1 - 0.6 10.0 5.9 4.7 7.1 0.9 2.7 3 0 0 3 3 3 0 CD20-like family Lon_C PF05362.8 AET40573.1 - 8.6e-67 224.4 0.0 2.8e-66 222.7 0.0 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 AET40573.1 - 8.4e-37 126.8 1.2 8.4e-37 126.8 0.8 2.1 3 0 0 3 3 3 1 ATP-dependent protease La (LON) domain AAA PF00004.24 AET40573.1 - 5e-23 81.7 0.0 1.9e-22 79.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AET40573.1 - 2.3e-06 27.6 0.0 7.5e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 AET40573.1 - 2.4e-06 27.0 0.0 6.2e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 AET40573.1 - 9.9e-06 25.3 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AET40573.1 - 1.2e-05 25.4 0.0 0.00042 20.4 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AET40573.1 - 0.00013 22.8 1.5 0.00026 21.8 0.0 2.5 3 1 0 3 3 1 1 AAA domain AAA_16 PF13191.1 AET40573.1 - 0.00017 21.6 0.0 0.00083 19.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 AET40573.1 - 0.00092 19.1 0.0 0.0045 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AET40573.1 - 0.0015 17.6 0.0 0.011 14.8 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 AET40573.1 - 0.0018 17.0 0.0 0.0035 16.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RNA_helicase PF00910.17 AET40573.1 - 0.0069 16.5 0.0 0.087 13.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 AET40573.1 - 0.0095 16.2 3.7 0.018 15.3 0.0 3.1 4 0 0 4 4 2 1 AAA domain DUF258 PF03193.11 AET40573.1 - 0.025 13.7 0.0 0.063 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SKI PF01202.17 AET40573.1 - 0.029 14.2 1.8 0.033 14.0 0.0 2.1 2 0 0 2 2 1 0 Shikimate kinase IstB_IS21 PF01695.12 AET40573.1 - 0.089 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 AET40573.1 - 0.17 11.3 1.0 2.7 7.4 0.0 2.3 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 AET40573.1 - 1.7 8.9 4.9 0.85 9.9 0.1 2.8 3 0 0 3 3 3 0 ABC transporter CBFD_NFYB_HMF PF00808.18 AET40574.1 - 1e-25 89.5 0.1 1.5e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AET40574.1 - 8.5e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 AET40574.1 - 0.01 15.5 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 1 Bromodomain associated TFIID_20kDa PF03847.8 AET40574.1 - 0.052 13.8 0.4 0.13 12.5 0.1 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Rft-1 PF04506.8 AET40575.1 - 1.7e-159 531.7 38.7 2e-159 531.5 26.8 1.0 1 0 0 1 1 1 1 Rft protein DUF2518 PF10726.4 AET40575.1 - 2.3 7.7 6.2 0.63 9.5 1.4 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) Exo_endo_phos PF03372.18 AET40576.1 - 4.2e-14 53.1 0.0 6.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 AET40576.1 - 2.3e-12 46.5 0.0 2.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Sigma_reg_N PF13800.1 AET40577.1 - 0.061 13.3 0.2 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 Sigma factor regulator N-terminal BNR PF02012.15 AET40578.1 - 1.7e-11 42.1 33.7 0.72 9.9 0.9 11.3 11 0 0 11 11 11 6 BNR/Asp-box repeat BNR_2 PF13088.1 AET40578.1 - 1.8e-05 24.1 1.3 2.2 7.4 0.0 5.2 3 3 1 4 4 4 3 BNR repeat-like domain Mo-co_dimer PF03404.11 AET40578.1 - 0.31 10.6 3.1 10 5.7 0.0 4.3 5 0 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.20 AET40579.1 - 1.8e-72 243.5 0.0 2.2e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40579.1 - 2.6e-32 111.9 0.0 3.4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40579.1 - 0.013 14.5 0.0 0.043 12.7 0.0 1.8 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.9 AET40579.1 - 0.054 12.5 0.1 0.089 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET40579.1 - 0.065 12.9 0.8 0.17 11.5 0.1 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family AcetylCoA_hydro PF02550.10 AET40580.1 - 1e-63 214.6 0.0 1.6e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 AET40580.1 - 1.2e-38 132.2 0.0 2e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.7 AET40580.1 - 0.00087 18.0 0.1 0.006 15.3 0.1 1.9 2 0 0 2 2 2 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.18 AET40580.1 - 0.028 13.6 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Coenzyme A transferase Acid_PPase PF12689.2 AET40581.1 - 1.3e-38 132.2 0.0 3.8e-38 130.7 0.0 1.6 1 1 0 1 1 1 1 Acid Phosphatase MerR_2 PF13591.1 AET40582.1 - 0.25 10.9 1.6 0.4 10.3 1.1 1.3 1 0 0 1 1 1 0 MerR HTH family regulatory protein FANCL_C PF11793.3 AET40583.1 - 7.7e-05 22.5 11.1 5.6 7.0 0.1 5.4 5 0 0 5 5 5 4 FANCL C-terminal domain VP_N-CPKC PF11475.3 AET40583.1 - 0.037 13.5 18.1 2.4 7.7 0.1 5.2 6 0 0 6 6 6 0 Virion protein N terminal domain RRM_1 PF00076.17 AET40584.1 - 9e-45 150.1 0.0 3.9e-21 74.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET40584.1 - 1.5e-30 104.9 0.0 1.6e-16 60.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET40584.1 - 9.7e-20 70.1 0.0 2.3e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AET40584.1 - 0.067 12.9 0.1 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 AET40584.1 - 0.1 12.3 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain Arrestin_N PF00339.24 AET40585.1 - 3.9e-20 72.1 0.0 2e-19 69.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 AET40585.1 - 1.6e-06 28.2 0.8 1.8e-05 24.8 0.0 2.6 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain RNase_PH PF01138.16 AET40586.1 - 2.8e-21 76.2 0.0 4.2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TGT PF01702.13 AET40586.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase PEMT PF04191.8 AET40587.1 - 1.2e-52 176.4 19.8 4.6e-30 103.8 2.3 3.5 3 0 0 3 3 3 2 Phospholipid methyltransferase ICMT PF04140.9 AET40587.1 - 1.1 9.5 8.2 1.2 9.3 0.3 3.3 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Septin PF00735.13 AET40588.1 - 1.2e-112 375.4 3.1 1.2e-112 375.4 2.2 2.7 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 AET40588.1 - 0.00012 21.9 3.3 0.00016 21.6 0.4 2.7 2 1 0 2 2 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AET40588.1 - 0.00097 18.3 1.5 0.0021 17.2 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AET40588.1 - 0.0013 18.7 0.5 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AET40588.1 - 0.0042 16.9 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 AET40588.1 - 0.058 12.8 0.0 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 AET40588.1 - 0.074 13.1 1.3 0.24 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AET40588.1 - 0.18 11.2 4.1 0.37 10.1 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 AET40588.1 - 0.25 11.1 10.5 3.1 7.5 0.0 3.7 3 1 0 3 3 3 0 Dynamin family DUF2937 PF11157.3 AET40588.1 - 0.47 9.7 4.9 0.89 8.8 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF342 PF03961.8 AET40588.1 - 0.83 7.9 14.8 1.5 7.1 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AIG1 PF04548.11 AET40588.1 - 0.83 8.7 7.4 1.3 8.0 0.0 3.1 3 0 0 3 3 3 0 AIG1 family AAA_24 PF13479.1 AET40588.1 - 1.3 8.5 5.7 1.7 8.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 AET40588.1 - 5.1 7.3 9.5 1.6 9.0 0.6 2.9 2 1 0 2 2 2 0 ABC transporter IncA PF04156.9 AET40588.1 - 5.5 6.5 16.2 12 5.3 11.2 1.6 1 0 0 1 1 1 0 IncA protein SHNi-TPR PF10516.4 AET40589.1 - 2.2e-20 71.5 4.5 3.8e-18 64.4 1.4 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_11 PF13414.1 AET40589.1 - 4.3e-05 23.0 10.0 0.0008 19.0 0.6 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 AET40589.1 - 0.0015 18.4 13.8 0.0072 16.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 AET40589.1 - 0.0066 16.3 4.1 0.06 13.3 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 AET40589.1 - 0.059 13.3 0.1 0.059 13.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 AET40589.1 - 0.085 12.4 5.3 0.26 10.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 AET40589.1 - 0.6 10.8 13.9 0.1 13.3 3.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AET40589.1 - 2.1 8.5 11.9 4.2 7.5 2.1 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AET40589.1 - 2.3 8.1 11.4 1.9 8.4 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 AET40589.1 - 7.7 6.5 7.8 5.3 7.0 0.1 3.9 5 1 0 5 5 5 0 Tetratricopeptide repeat UPF0121 PF03661.8 AET40590.1 - 5.3e-09 35.6 6.5 2.5e-08 33.4 4.5 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Scs3p PF10261.4 AET40590.1 - 0.032 13.2 0.2 0.032 13.2 0.2 1.7 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2_C PF14360.1 AET40590.1 - 4.4 7.6 11.7 0.36 11.1 3.3 2.5 2 1 0 2 2 2 0 PAP2 superfamily C-terminal HSP70 PF00012.15 AET40591.1 - 6.9e-273 906.0 7.5 7.9e-273 905.8 5.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AET40591.1 - 7.3e-18 64.2 0.0 1.4e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AET40591.1 - 0.0027 17.3 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 AET40591.1 - 0.0032 16.6 1.0 0.01 14.9 0.0 2.3 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DUF1484 PF07363.6 AET40591.1 - 0.072 13.4 0.4 13 6.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) PMBR PF09373.5 AET40591.1 - 0.83 9.7 0.0 0.83 9.7 0.0 2.4 3 0 0 3 3 3 0 Pseudomurein-binding repeat COX6A PF02046.10 AET40592.1 - 4.8e-41 139.3 0.8 5.1e-41 139.2 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.27 AET40593.1 - 1.4e-17 62.8 1.7 0.0071 16.1 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Ribosomal_S26e PF01283.14 AET40594.1 - 4.8e-51 171.8 8.5 5.6e-51 171.5 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 AET40594.1 - 0.043 12.6 0.1 0.047 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) COX5B PF01215.14 AET40595.1 - 4e-53 178.7 0.0 4.6e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb WSC PF01822.14 AET40597.1 - 1.1e-10 41.2 10.5 1.1e-10 41.2 7.3 3.4 3 1 0 3 3 3 1 WSC domain SIT PF15330.1 AET40597.1 - 0.023 14.7 0.1 0.023 14.7 0.1 2.9 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Peptidase_U32 PF01136.14 AET40597.1 - 0.025 13.5 2.0 0.054 12.4 1.4 1.5 1 0 0 1 1 1 0 Peptidase family U32 Toxin_38 PF14866.1 AET40597.1 - 0.048 13.7 1.0 0.09 12.8 0.7 1.3 1 0 0 1 1 1 0 Potassium channel toxin Vpu PF00558.14 AET40597.1 - 0.1 12.1 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Vpu protein EphA2_TM PF14575.1 AET40597.1 - 0.12 12.8 0.1 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.1 AET40597.1 - 0.12 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Baculo_11_kDa PF06143.6 AET40597.1 - 0.14 11.4 0.6 0.37 10.1 0.4 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4233 PF14017.1 AET40597.1 - 0.28 11.1 3.7 0.68 9.8 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4233) YajC PF02699.10 AET40597.1 - 0.85 9.3 4.9 1 9.0 0.4 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit zf-C2H2 PF00096.21 AET40598.1 - 1.7e-06 27.9 19.0 6.1e-05 23.1 2.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET40598.1 - 0.0043 17.2 9.3 0.0075 16.5 1.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET40598.1 - 0.053 13.8 1.2 0.053 13.8 0.8 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Zip PF02535.17 AET40598.1 - 0.072 12.0 1.4 0.092 11.7 1.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 AET40598.1 - 1.2 7.3 16.8 1.6 6.9 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Clp1 PF06807.9 AET40599.1 - 2.8e-06 27.2 0.0 5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 AET40599.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AET40599.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 AET40600.1 - 3.5e-93 308.7 0.0 1.6e-46 157.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AET40600.1 - 7.1e-15 54.6 0.0 3.7e-08 32.7 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AET40600.1 - 1.9e-12 48.0 0.2 1.3e-06 29.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 AET40600.1 - 2e-11 44.2 0.4 0.00051 20.0 0.0 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 AET40600.1 - 9e-11 41.9 0.0 0.00057 19.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AET40600.1 - 3e-10 40.3 0.1 0.018 15.2 0.0 5.1 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.1 AET40600.1 - 1.1e-09 38.3 0.0 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AET40600.1 - 2.4e-09 36.5 0.0 0.0012 17.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 AET40600.1 - 2.8e-09 36.8 0.6 0.005 16.5 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 AET40600.1 - 3.1e-09 37.2 0.2 0.00011 22.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 AET40600.1 - 4.5e-09 36.2 0.0 0.0051 16.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.8 AET40600.1 - 1.6e-08 33.6 0.0 0.00071 18.4 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 AET40600.1 - 1.7e-07 31.3 0.0 0.014 15.5 0.0 3.2 3 0 0 3 3 2 2 RNA helicase Vps4_C PF09336.5 AET40600.1 - 6.3e-07 29.1 0.2 0.00022 21.0 0.0 3.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.22 AET40600.1 - 9.7e-07 29.1 0.1 0.034 14.4 0.0 3.2 3 0 0 3 3 2 2 ABC transporter IstB_IS21 PF01695.12 AET40600.1 - 2.5e-06 27.0 0.1 0.047 13.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 AET40600.1 - 4.5e-06 26.7 0.0 0.033 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AET40600.1 - 5e-06 26.1 0.3 0.071 12.8 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 AET40600.1 - 6.8e-06 25.3 0.2 0.061 12.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI SKI PF01202.17 AET40600.1 - 1.5e-05 24.9 0.0 0.096 12.5 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase Cytidylate_kin2 PF13189.1 AET40600.1 - 1.5e-05 24.9 0.0 0.004 17.0 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_25 PF13481.1 AET40600.1 - 1.9e-05 24.1 3.4 1.9 7.8 0.0 4.4 2 2 1 4 4 4 1 AAA domain AAA_3 PF07726.6 AET40600.1 - 3.7e-05 23.3 0.0 0.32 10.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AET40600.1 - 0.00028 20.6 0.2 1.7 8.2 0.0 3.8 4 1 0 4 4 3 1 NACHT domain Rad17 PF03215.10 AET40600.1 - 0.00031 19.5 0.0 0.18 10.4 0.0 2.4 3 0 0 3 3 2 2 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 AET40600.1 - 0.00039 20.4 0.1 0.68 9.9 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 AET40600.1 - 0.00058 18.8 0.1 1.1 8.1 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.13 AET40600.1 - 0.00073 19.1 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 AET40600.1 - 0.00081 18.8 0.0 0.19 11.1 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 AET40600.1 - 0.0011 17.8 0.0 0.43 9.3 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain AAA_11 PF13086.1 AET40600.1 - 0.0015 18.1 0.7 2.1 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 AET40600.1 - 0.0016 17.4 0.0 0.17 10.7 0.0 3.0 3 0 0 3 3 2 1 Protein of unknown function (DUF815) CPT PF07931.7 AET40600.1 - 0.0049 16.5 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 AET40600.1 - 0.0068 15.5 0.0 2.2 7.3 0.0 3.2 3 0 0 3 3 3 1 KaiC ATP-synt_ab PF00006.20 AET40600.1 - 0.0077 15.7 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 AET40600.1 - 0.009 15.2 0.1 2.9 7.0 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein SRPRB PF09439.5 AET40600.1 - 0.012 14.7 0.0 1.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 AET40600.1 - 0.013 15.1 0.5 8.8 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 AET40600.1 - 0.017 14.9 0.1 2.6 7.8 0.0 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit IPT PF01745.11 AET40600.1 - 0.019 14.1 1.6 19 4.3 0.1 3.2 3 0 0 3 3 3 0 Isopentenyl transferase AAA_31 PF13614.1 AET40600.1 - 0.023 14.6 0.0 0.36 10.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 AET40600.1 - 0.064 12.7 0.0 8.7 5.8 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 AET40600.1 - 0.07 12.8 3.0 5.5 6.6 0.0 3.7 4 0 0 4 4 4 0 NTPase AFG1_ATPase PF03969.11 AET40600.1 - 0.1 11.3 0.2 8.8 5.0 0.1 2.9 2 1 0 2 2 2 0 AFG1-like ATPase DUF258 PF03193.11 AET40600.1 - 0.11 11.7 0.0 0.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ANF_receptor PF01094.23 AET40600.1 - 0.22 10.2 0.3 0.99 8.1 0.1 1.9 2 0 0 2 2 2 0 Receptor family ligand binding region AAA_23 PF13476.1 AET40600.1 - 0.46 10.7 8.7 1.4 9.2 0.0 3.6 3 0 0 3 3 2 0 AAA domain Complex1_LYR PF05347.10 AET40601.1 - 0.11 12.3 3.0 0.34 10.7 2.1 1.8 1 0 0 1 1 1 0 Complex 1 protein (LYR family) KH_1 PF00013.24 AET40602.1 - 5.7e-14 51.5 0.0 2.2e-07 30.3 0.0 4.4 4 0 0 4 4 4 2 KH domain KH_3 PF13014.1 AET40602.1 - 3.3e-10 39.3 1.7 5.7e-05 22.6 0.0 4.8 5 0 0 5 5 5 2 KH domain Phlebovirus_G2 PF07245.6 AET40602.1 - 0.0047 15.2 0.0 0.007 14.6 0.0 1.1 1 0 0 1 1 1 1 Phlebovirus glycoprotein G2 Ribosomal_L19 PF01245.15 AET40602.1 - 0.084 12.6 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L19 RNase_H2-Ydr279 PF09468.5 AET40603.1 - 0.02 14.1 0.6 0.024 13.8 0.4 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CytoC_RC PF02276.13 AET40603.1 - 0.38 9.8 3.0 1.2 8.2 0.6 2.1 2 0 0 2 2 2 0 Photosynthetic reaction centre cytochrome C subunit UPF0242 PF06785.6 AET40603.1 - 0.6 8.7 10.8 7.5 5.1 8.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) ChaC PF04752.7 AET40604.1 - 2e-50 171.2 0.0 2.3e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GDI PF00996.13 AET40605.1 - 2.3e-213 708.3 0.2 2.6e-213 708.1 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 AET40605.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LSM PF01423.17 AET40606.1 - 1.8e-16 59.4 0.4 2.4e-16 59.0 0.3 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 AET40606.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.1 AET40606.1 - 0.089 12.7 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF1025 PF06262.6 AET40607.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase zf-CCHC_4 PF14392.1 AET40607.1 - 0.11 12.2 2.2 0.45 10.2 1.1 2.2 3 0 0 3 3 3 0 Zinc knuckle GHMP_kinases_N PF00288.21 AET40608.1 - 7.6e-22 77.1 0.7 1.9e-21 75.8 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AET40608.1 - 1.6e-05 24.9 0.4 0.0011 19.1 0.2 2.8 1 1 1 2 2 2 1 GHMP kinases C terminal Mtc PF03820.12 AET40609.1 - 8.7e-127 422.0 0.7 9.7e-127 421.8 0.5 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.27 AET40610.1 - 1.2e-34 116.9 6.5 9.7e-08 31.6 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 AET40610.1 - 1.7e-24 85.5 0.2 3e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 AET40610.1 - 7.3e-07 27.7 3.8 0.015 13.4 0.2 3.3 2 2 1 3 3 3 2 Nucleoporin Nup120/160 MFS_1 PF07690.11 AET40611.1 - 1.4e-27 96.3 39.7 1.4e-27 96.3 27.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Tubulin_3 PF14881.1 AET40612.1 - 1.7e-21 76.5 0.0 3.2e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 AET40612.1 - 3e-12 46.6 0.0 5.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 AET40612.1 - 0.0042 16.9 0.0 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain IPPT PF01715.12 AET40613.1 - 6.8e-79 264.4 0.2 9.9e-79 263.9 0.2 1.2 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 AET40613.1 - 1.5e-07 32.2 1.5 4.8e-07 30.6 0.2 2.5 2 1 0 2 2 2 1 AAA domain IPT PF01745.11 AET40613.1 - 1.2e-05 24.6 0.1 0.00052 19.2 0.0 2.9 3 0 0 3 3 3 1 Isopentenyl transferase AAA_18 PF13238.1 AET40613.1 - 2e-05 24.8 0.1 0.00017 21.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AET40613.1 - 0.00022 20.3 0.0 0.00044 19.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 AET40613.1 - 0.00061 19.6 0.0 0.01 15.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain PPV_E1_C PF00519.12 AET40613.1 - 0.0031 16.2 0.9 0.0083 14.7 0.1 1.8 2 0 0 2 2 2 1 Papillomavirus helicase DUF258 PF03193.11 AET40613.1 - 0.0052 15.9 0.0 0.0088 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AET40613.1 - 0.0053 16.8 0.0 0.71 10.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain Hpr_kinase_C PF07475.7 AET40613.1 - 0.04 13.2 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PRK PF00485.13 AET40613.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 AET40613.1 - 0.07 13.3 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 AET40613.1 - 0.076 12.9 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AET40613.1 - 0.079 12.8 0.0 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AET40613.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AET40613.1 - 0.13 12.5 0.4 0.43 10.8 0.1 2.1 2 1 0 2 2 2 0 ABC transporter BRO1 PF03097.13 AET40614.1 - 3.3e-83 279.5 4.9 3.3e-83 279.5 3.4 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 AET40614.1 - 2e-31 109.0 18.9 2.3e-30 105.6 11.7 2.6 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF745 PF05335.8 AET40614.1 - 5.2 6.5 7.8 1.1 8.7 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Myb_DNA-binding PF00249.26 AET40616.1 - 8.7e-22 76.9 2.7 4.3e-12 45.8 0.3 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AET40616.1 - 2.8e-19 68.9 3.9 2.4e-12 46.7 1.8 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.3 AET40616.1 - 0.00012 21.4 1.3 0.00012 21.4 0.9 3.3 3 1 1 4 4 4 1 pre-mRNA splicing factor component Rap1_C PF11626.3 AET40616.1 - 0.014 15.2 0.3 0.052 13.4 0.0 2.1 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF776 PF05604.6 AET40617.1 - 0.012 15.8 0.1 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF776) DUF2383 PF09537.5 AET40617.1 - 0.019 15.2 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DnaJ PF00226.26 AET40618.1 - 7.4e-28 96.0 0.7 1.2e-27 95.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AET40618.1 - 1.7e-14 53.6 21.1 3.6e-14 52.5 14.6 1.6 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 AET40618.1 - 1.3e-12 47.4 0.0 9.7e-11 41.4 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain CytoC_RC PF02276.13 AET40618.1 - 0.067 12.2 0.2 0.09 11.8 0.1 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit GP38 PF05268.6 AET40618.1 - 0.11 11.8 7.5 0.18 11.1 5.2 1.3 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Cytochrome_CBB3 PF13442.1 AET40618.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.7 1 1 2 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III HypA PF01155.14 AET40618.1 - 0.27 10.9 11.0 1.9 8.2 0.5 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Spore_YabQ PF09578.5 AET40619.1 - 0.067 13.1 3.1 0.13 12.2 2.1 1.5 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) Glyco_hydro_72 PF03198.9 AET40620.1 - 1.6e-123 411.7 0.9 4.9e-123 410.1 0.3 1.7 2 0 0 2 2 2 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 AET40620.1 - 5.4e-08 32.0 0.0 1.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 AET40620.1 - 6.5e-06 25.5 0.1 9.2e-05 21.7 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 AET40621.1 - 4.2e-39 134.2 0.7 2.1e-16 59.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AET40621.1 - 5.2e-10 38.8 0.9 0.0035 16.4 0.2 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase RRM_1 PF00076.17 AET40622.1 - 1.1e-09 37.7 0.0 1.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AET40622.1 - 1.3e-09 37.6 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 AET40622.1 - 9.6e-08 31.9 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET40622.1 - 4.5e-05 23.2 0.0 7.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PsaN PF05479.6 AET40622.1 - 0.042 13.8 0.1 0.064 13.2 0.1 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) GMP_synt_C PF00958.17 AET40623.1 - 2.5e-41 139.2 0.0 1e-40 137.3 0.0 2.0 2 0 0 2 2 2 1 GMP synthase C terminal domain GATase PF00117.23 AET40623.1 - 1.2e-40 139.0 0.0 2.2e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 AET40623.1 - 2.1e-08 33.3 0.0 4.1e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 AET40623.1 - 5.8e-07 29.1 0.0 5.2e-06 26.0 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 PAPS_reduct PF01507.14 AET40623.1 - 0.0028 17.4 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 AET40623.1 - 0.0039 16.5 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 AET40623.1 - 0.0058 15.2 0.1 0.012 14.1 0.0 1.5 1 0 0 1 1 1 1 tRNA methyl transferase Arginosuc_synth PF00764.14 AET40623.1 - 0.0079 15.2 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.9 AET40623.1 - 0.02 14.3 0.0 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 AET40623.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase HEM4 PF02602.10 AET40624.1 - 1.6e-41 142.0 0.0 1.8e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD CLAMP PF14769.1 AET40624.1 - 0.05 13.7 0.2 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 MAF_flag10 PF01973.13 AET40624.1 - 0.078 12.4 0.2 0.4 10.1 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF115 TRAPPC10 PF12584.3 AET40625.1 - 4.9e-16 58.5 0.0 1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 AET40625.1 - 0.0047 16.4 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 GHMP_kinases_N PF00288.21 AET40627.1 - 1.7e-13 50.4 0.9 2.9e-13 49.6 0.2 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AET40627.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal FSH1 PF03959.8 AET40629.1 - 4.3e-65 219.1 0.0 4.9e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 AET40629.1 - 7.4e-08 32.2 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AET40629.1 - 5.8e-05 22.6 0.0 0.00019 20.9 0.0 1.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 AET40629.1 - 0.00066 19.6 0.0 0.072 12.9 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 AET40629.1 - 0.16 11.2 0.0 0.39 9.9 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family UCH PF00443.24 AET40630.1 - 1.3e-57 194.9 6.9 1.3e-57 194.9 4.8 1.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AET40630.1 - 2.8e-28 99.2 6.8 3.7e-28 98.8 4.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AET40630.1 - 2e-11 43.8 11.0 2e-11 43.8 7.6 4.1 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Phosducin PF02114.11 AET40631.1 - 1.4e-12 46.9 7.9 3.5e-11 42.3 5.4 2.0 1 1 0 1 1 1 1 Phosducin Mre11_DNA_bind PF04152.9 AET40632.1 - 2.2e-46 157.9 0.0 6.5e-46 156.3 0.0 1.9 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 AET40632.1 - 4.2e-28 98.1 0.6 6.9e-28 97.4 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AET40632.1 - 0.00047 20.0 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1993 PF09351.5 AET40632.1 - 0.01 15.8 0.6 0.021 14.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) His_Phos_1 PF00300.17 AET40633.1 - 2e-29 102.7 0.1 2.5e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Prominin PF05478.6 AET40633.1 - 0.059 10.9 0.0 0.06 10.8 0.0 1.2 1 0 0 1 1 1 0 Prominin Rhodanese PF00581.15 AET40634.1 - 3.7e-16 59.4 0.1 9.2e-16 58.1 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain Rhodanese PF00581.15 AET40635.1 - 1.4e-11 44.7 0.0 1.7e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain VHP PF02209.14 AET40635.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Villin headpiece domain DUF947 PF06102.7 AET40636.1 - 4.7e-41 140.4 30.5 4.7e-41 140.4 21.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF947) CTF_NFI PF00859.13 AET40636.1 - 0.33 10.6 4.4 0.5 10.0 3.0 1.2 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region MRP_L53 PF10780.4 AET40637.1 - 1.2e-18 66.7 1.3 1.8e-18 66.2 0.9 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Thioredoxin PF00085.15 AET40638.1 - 7e-23 80.2 0.1 1.2e-21 76.3 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 AET40638.1 - 1.7e-07 31.4 0.1 5.2e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AET40638.1 - 1.5e-06 28.1 0.1 3.1e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 AET40638.1 - 3.5e-05 23.8 0.1 0.0011 19.0 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 AET40638.1 - 0.00011 22.0 0.2 0.019 14.7 0.0 3.4 3 1 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.16 AET40638.1 - 0.00052 19.6 0.1 0.00098 18.8 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.1 AET40638.1 - 0.037 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 AET40638.1 - 0.067 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin domain AMMECR1 PF01871.12 AET40639.1 - 7.4e-35 119.5 0.0 1e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 SNF2_N PF00176.18 AET40640.1 - 7.9e-82 274.4 0.3 1.7e-81 273.2 0.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AET40640.1 - 9.4e-18 63.8 0.1 8.9e-16 57.5 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 AET40640.1 - 1e-15 57.6 4.1 2e-15 56.7 0.3 3.3 1 1 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.20 AET40640.1 - 1.2e-12 47.5 0.6 4.4e-12 45.7 0.4 2.0 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.6 AET40640.1 - 1.2e-10 40.5 2.3 1.2e-10 40.5 1.6 2.9 4 0 0 4 4 4 1 QLQ HSA PF07529.8 AET40640.1 - 0.0065 16.2 8.7 0.0065 16.2 6.0 2.7 2 0 0 2 2 2 1 HSA TAFII55_N PF04658.8 AET40641.1 - 4e-55 185.7 0.1 4e-55 185.7 0.1 2.2 3 0 0 3 3 3 1 TAFII55 protein conserved region Cupredoxin_1 PF13473.1 AET40641.1 - 0.14 12.1 2.4 0.86 9.5 0.3 2.5 2 0 0 2 2 2 0 Cupredoxin-like domain RrnaAD PF00398.15 AET40642.1 - 6.7e-43 146.5 0.0 8.6e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF3987 PF13148.1 AET40643.1 - 1.5 7.2 5.2 3.4 6.1 3.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) S1 PF00575.18 AET40644.1 - 2.1e-63 210.3 33.0 1.2e-13 50.9 0.6 12.6 12 1 0 12 12 12 10 S1 RNA binding domain TPR_19 PF14559.1 AET40644.1 - 3e-05 24.2 0.0 0.56 10.5 0.0 3.3 2 1 2 4 4 4 3 Tetratricopeptide repeat Suf PF05843.9 AET40644.1 - 3.8e-05 23.5 8.0 0.00023 20.9 1.3 2.9 1 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 AET40644.1 - 4.1e-05 23.8 0.1 0.39 11.4 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 AET40644.1 - 0.0019 18.8 0.0 1.1 10.0 0.1 3.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 AET40644.1 - 0.03 14.2 0.0 7.3 6.6 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 AET40644.1 - 0.053 12.5 2.3 2.7 6.9 0.1 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 AET40644.1 - 0.072 12.7 0.0 4.8 6.8 0.0 2.6 2 0 0 2 2 2 0 TPR repeat RNA_pol_Rbc25 PF08292.7 AET40644.1 - 1.9 8.7 9.3 1.7 8.8 0.0 5.4 6 0 0 6 6 6 0 RNA polymerase III subunit Rpc25 P5-ATPase PF12409.3 AET40645.1 - 5e-36 123.1 1.2 5e-36 123.1 0.8 2.3 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 AET40645.1 - 3.9e-25 89.1 0.0 1.1e-24 87.6 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AET40645.1 - 2.2e-23 82.5 0.0 4.1e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AET40645.1 - 1.8e-16 61.2 0.0 2.8e-11 44.2 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AET40645.1 - 1.8e-05 24.5 0.0 4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AET40645.1 - 0.0075 15.8 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mpv17_PMP22 PF04117.7 AET40646.1 - 1.8e-19 69.1 0.7 1.8e-19 69.1 0.5 2.6 2 1 1 3 3 3 1 Mpv17 / PMP22 family S10_plectin PF03501.10 AET40647.1 - 1e-41 140.6 0.2 1.2e-41 140.4 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF505 PF04458.7 AET40647.1 - 0.0073 14.4 0.2 0.0083 14.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF505) HTH_45 PF14947.1 AET40647.1 - 0.032 14.0 0.2 0.053 13.3 0.2 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DUF4364 PF14277.1 AET40647.1 - 0.074 12.6 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) TrmB PF01978.14 AET40647.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.9 AET40647.1 - 0.28 10.9 3.2 0.15 11.8 0.5 1.9 2 1 0 2 2 2 0 Transcriptional regulator PadR-like family DUF2250 PF10007.4 AET40647.1 - 1.2 9.0 3.4 14 5.6 0.7 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) Septin PF00735.13 AET40648.1 - 5e-94 314.4 0.0 7.7e-94 313.8 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AET40648.1 - 1.3e-05 25.1 0.1 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AET40648.1 - 6e-05 22.9 0.2 0.056 13.2 0.1 3.0 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 AET40648.1 - 0.00023 20.3 0.1 0.00059 19.0 0.1 1.7 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 AET40648.1 - 0.00029 20.0 0.1 0.00087 18.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 AET40648.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 AET40648.1 - 0.023 13.6 0.1 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 AET40648.1 - 0.031 14.7 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_24 PF13479.1 AET40648.1 - 0.036 13.6 0.0 0.099 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AET40648.1 - 0.039 13.3 0.1 0.092 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 AET40648.1 - 0.081 12.7 1.4 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 AET40648.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.22 AET40648.1 - 0.14 11.5 0.7 2.4 7.5 0.2 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PIN_4 PF13638.1 AET40649.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 PIN domain FA_hydroxylase PF04116.8 AET40650.1 - 3e-16 59.8 19.6 3e-16 59.8 13.6 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase_5 PF13507.1 AET40651.1 - 1.2e-95 319.3 0.0 1.8e-95 318.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 AET40651.1 - 5.4e-51 172.6 0.0 2.3e-28 99.1 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AET40651.1 - 4.2e-22 78.1 0.0 1.4e-21 76.5 0.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF2462 PF09495.5 AET40652.1 - 1.1e-15 58.0 9.9 1.1e-15 58.0 6.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) 60KD_IMP PF02096.15 AET40653.1 - 6.2e-15 55.3 12.5 7.7e-14 51.8 8.6 2.0 1 1 0 1 1 1 1 60Kd inner membrane protein Spt4 PF06093.8 AET40654.1 - 1.1e-28 98.8 0.5 1.3e-28 98.6 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-TFIIB PF13453.1 AET40654.1 - 0.037 13.2 0.5 0.067 12.3 0.4 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger MRP-L27 PF09809.4 AET40655.1 - 2.4e-29 101.2 0.3 3.6e-29 100.6 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 WD40 PF00400.27 AET40656.1 - 7.9e-16 57.2 0.0 0.00013 21.7 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 AET40656.1 - 8.4e-05 21.9 0.0 0.035 13.5 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RCC1_2 PF13540.1 AET40657.1 - 1.8e-18 65.6 6.0 3e-06 26.6 0.2 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 AET40657.1 - 5.7e-15 55.2 0.4 5.9e-05 23.1 0.0 7.0 6 2 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 AET40657.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like Esterase PF00756.15 AET40658.1 - 8.5e-55 185.8 0.0 9.7e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 AET40658.1 - 0.031 14.0 0.0 0.046 13.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Paf1 PF03985.8 AET40659.1 - 3e-143 477.6 15.4 3.4e-143 477.5 10.7 1.0 1 0 0 1 1 1 1 Paf1 CBFD_NFYB_HMF PF00808.18 AET40661.1 - 4.6e-06 26.5 0.1 8.4e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AET40661.1 - 0.0094 16.0 0.1 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DSPc PF00782.15 AET40662.1 - 2.3e-27 95.1 0.5 6.5e-21 74.3 0.1 3.6 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AET40662.1 - 5.6e-07 29.1 0.1 5.9e-05 22.5 0.1 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AET40662.1 - 0.056 13.5 0.3 0.5 10.3 0.1 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate PALP PF00291.20 AET40663.1 - 9.2e-58 195.8 0.0 1.1e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L17 PF01196.14 AET40664.1 - 1.3e-26 92.9 0.0 2.6e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 adh_short PF00106.20 AET40666.1 - 2e-23 83.1 0.0 2.9e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AET40666.1 - 7.2e-17 61.6 0.0 9.8e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 AET40666.1 - 1.4e-06 27.4 0.0 2.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 AET40666.1 - 0.00049 19.9 0.0 0.00062 19.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AET40666.1 - 0.0016 17.8 0.0 0.0045 16.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 AET40666.1 - 0.051 13.6 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4381 PF14316.1 AET40666.1 - 0.26 11.3 1.1 0.52 10.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-C2H2_2 PF12756.2 AET40667.1 - 1.1e-34 118.5 4.2 1.3e-32 111.8 1.7 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AET40667.1 - 0.051 13.9 0.3 0.051 13.9 0.2 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 AET40667.1 - 0.21 11.7 1.5 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Phosphodiest PF01663.17 AET40668.1 - 7e-15 55.2 1.8 3.7e-13 49.5 1.2 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 AET40668.1 - 0.00012 21.5 0.0 0.00025 20.4 0.0 1.6 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 AET40668.1 - 0.086 12.0 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Sulfatase Vpu PF00558.14 AET40668.1 - 0.73 9.4 3.5 19 4.8 0.0 3.0 3 0 0 3 3 3 0 Vpu protein Ribosomal_L37 PF08561.5 AET40669.1 - 2.8e-27 94.1 0.2 3.3e-27 93.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Nup88 PF10168.4 AET40670.1 - 4.4e-05 21.5 0.0 4.4e-05 21.5 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore component Nsp1_C PF05064.8 AET40670.1 - 0.41 10.2 3.7 0.22 11.1 0.4 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF1674 PF07896.7 AET40671.1 - 9.7e-18 64.1 1.3 1.4e-17 63.6 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Aminotran_1_2 PF00155.16 AET40672.1 - 1.8e-56 191.6 0.0 2.1e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AET40672.1 - 0.00044 19.0 0.0 0.003 16.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AET40672.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 AET40672.1 - 0.0016 16.8 0.0 0.0043 15.3 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 AET40672.1 - 0.03 12.9 0.0 0.052 12.1 0.0 1.3 1 0 0 1 1 1 0 Allinase HbrB PF08539.6 AET40673.1 - 5.6e-29 101.0 0.5 1e-28 100.1 0.1 1.6 2 0 0 2 2 2 1 HbrB-like SPT16 PF08644.6 AET40673.1 - 0.049 13.4 0.2 5.7 6.7 0.2 2.7 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Pkinase PF00069.20 AET40674.1 - 3.3e-31 108.3 0.0 4.9e-30 104.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40674.1 - 6.6e-19 67.9 0.0 9.3e-18 64.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase zf-ribbon_3 PF13248.1 AET40674.1 - 0.11 11.7 0.3 0.24 10.6 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 AET40674.1 - 0.12 11.9 1.7 0.22 11.0 1.2 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.1 AET40675.1 - 3.6e-28 96.4 49.4 8.4e-09 35.3 1.0 7.7 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 AET40675.1 - 2.9e-26 90.1 56.1 1.2e-05 25.4 1.9 9.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET40675.1 - 4e-16 58.0 65.5 3.9e-05 23.6 0.9 9.8 9 0 0 9 9 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AET40675.1 - 6.4e-11 42.0 33.4 0.00017 21.6 0.3 6.7 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AET40675.1 - 3.6e-10 39.3 26.8 9.1e-05 22.2 0.3 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 AET40675.1 - 1.7e-06 28.0 32.7 0.011 15.9 0.5 7.0 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 AET40675.1 - 5.7e-05 22.6 19.0 0.42 10.3 2.0 5.4 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-Di19 PF05605.7 AET40675.1 - 0.00063 19.8 8.1 0.0017 18.4 0.9 6.5 3 3 2 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.4 AET40675.1 - 1.3 8.9 8.6 7.9 6.4 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger domain DUF2225 PF09986.4 AET40675.1 - 2.1 7.7 13.9 0.32 10.4 0.9 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Phage_Orf51 PF06194.6 AET40675.1 - 7.8 6.6 7.5 3.9 7.6 1.0 3.4 3 1 1 4 4 4 0 Phage Conserved Open Reading Frame 51 Lysine_decarbox PF03641.9 AET40676.1 - 8.8e-45 151.7 0.1 2.4e-44 150.3 0.1 1.7 1 1 0 1 1 1 1 Possible lysine decarboxylase Inhibitor_Mig-6 PF11555.3 AET40676.1 - 0.095 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Myb_DNA-binding PF00249.26 AET40678.1 - 5.4e-23 80.7 1.1 5.2e-13 48.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AET40678.1 - 1.1e-19 70.3 3.0 3.5e-14 52.6 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 AET40678.1 - 0.076 12.9 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Tim54 PF11711.3 AET40679.1 - 8.8e-134 445.8 1.7 1e-133 445.6 1.2 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Vps26 PF03643.10 AET40680.1 - 3.8e-112 373.5 1.2 4.4e-112 373.3 0.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 AET40680.1 - 0.012 15.4 0.7 0.086 12.6 0.2 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain COX3 PF00510.13 AET40680.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit III DUF4497 PF14924.1 AET40680.1 - 0.13 12.6 0.0 0.9 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Pkinase PF00069.20 AET40681.1 - 5.9e-42 143.6 0.0 8.1e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40681.1 - 1.4e-21 76.7 0.0 1.8e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 AET40681.1 - 9.5e-10 38.1 0.1 1.5e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 AET40681.1 - 0.0025 16.8 0.0 0.005 15.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AET40681.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family rRNA_proc-arch PF13234.1 AET40683.1 - 5.4e-89 297.9 0.8 9e-89 297.1 0.6 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 AET40683.1 - 3.4e-62 208.8 0.4 6.5e-62 207.9 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 AET40683.1 - 9.3e-22 77.3 0.0 9.9e-21 73.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET40683.1 - 2.7e-06 27.1 0.0 5.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Snf7 PF03357.16 AET40685.1 - 4.5e-16 58.7 10.7 6.9e-16 58.0 7.4 1.2 1 0 0 1 1 1 1 Snf7 MutS_III PF05192.13 AET40685.1 - 0.55 9.9 5.2 1.1 8.9 3.6 1.5 1 0 0 1 1 1 0 MutS domain III Allexi_40kDa PF05549.6 AET40685.1 - 4.7 6.4 10.5 1.5 8.0 0.5 2.4 1 1 1 2 2 2 0 Allexivirus 40kDa protein UBX PF00789.15 AET40686.1 - 3.4e-17 62.2 0.0 6.3e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.20 AET40687.1 - 2.4e-58 197.3 0.0 3.3e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40687.1 - 6.4e-35 120.4 0.0 8.7e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40687.1 - 9.7e-07 28.0 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 AET40687.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 AET40687.1 - 0.016 14.7 0.1 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 AET40687.1 - 0.036 13.1 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AET40687.1 - 0.044 12.6 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 AET40687.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.17 AET40688.1 - 9.6e-42 142.1 0.4 6.4e-41 139.4 0.3 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 AET40688.1 - 1e-18 67.9 0.1 1.7e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET40688.1 - 5.9e-18 64.7 1.6 8.3e-17 60.9 1.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AET40688.1 - 8.8e-09 35.3 0.1 1.5e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AET40688.1 - 3.1e-07 29.7 0.0 4.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AET40688.1 - 3.1e-06 26.7 0.0 2.9e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AET40688.1 - 0.0024 17.1 0.3 0.0058 15.8 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 AET40688.1 - 0.032 14.3 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 AET40688.1 - 0.045 12.9 0.2 0.1 11.7 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF258 G-alpha PF00503.15 AET40688.1 - 0.045 12.4 1.2 4.9 5.7 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit SHMT PF00464.14 AET40689.1 - 1.5e-200 665.7 0.0 1.7e-200 665.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF619 PF04768.8 AET40690.1 - 9.2e-47 158.6 0.1 2.4e-46 157.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Sld5 PF05916.6 AET40691.1 - 1e-17 64.4 0.1 1.6e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein DUF1128 PF06569.6 AET40691.1 - 0.17 11.6 1.7 7.2 6.4 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1128) Drf_FH1 PF06346.7 AET40693.1 - 1.6e-05 24.4 3.6 0.0082 15.6 0.0 4.0 2 1 2 4 4 4 3 Formin Homology Region 1 Nucleoplasmin PF03066.10 AET40694.1 - 0.0005 19.6 5.4 0.00078 18.9 3.7 1.3 1 0 0 1 1 1 1 Nucleoplasmin BSP_II PF05432.6 AET40694.1 - 0.0024 17.2 7.8 0.0033 16.7 5.4 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Sigma70_ner PF04546.8 AET40694.1 - 0.023 14.3 6.6 0.034 13.7 4.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 AET40694.1 - 0.032 13.4 7.9 0.041 13.0 5.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.1 AET40694.1 - 0.06 13.0 1.7 0.069 12.8 0.4 1.7 2 0 0 2 2 2 0 FAM176 family TRAP_alpha PF03896.11 AET40694.1 - 0.47 9.4 3.9 0.84 8.5 2.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 AET40694.1 - 1.1 7.9 17.3 1.6 7.4 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Peptidase_M28 PF04389.12 AET40695.1 - 1.3e-32 113.0 0.0 1.9e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 AET40695.1 - 1.7e-11 43.6 0.0 4.4e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 AET40695.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 AET40695.1 - 0.0053 15.5 0.0 0.0081 14.9 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase DnaJ PF00226.26 AET40696.1 - 1.2e-19 69.7 4.7 3.6e-19 68.2 3.3 1.9 1 0 0 1 1 1 1 DnaJ domain DUF4175 PF13779.1 AET40696.1 - 3.2 5.3 22.4 4.5 4.8 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Aminotran_1_2 PF00155.16 AET40697.1 - 2.3e-62 211.0 0.0 2.7e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AET40697.1 - 0.00063 18.1 0.0 0.0014 16.9 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AET40697.1 - 0.0018 17.1 0.0 0.017 13.9 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AET40697.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NtA PF03146.10 AET40697.1 - 0.064 12.9 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Agrin NtA domain Aminotran_3 PF00202.16 AET40697.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III SMC_N PF02463.14 AET40698.1 - 2.9e-58 196.6 25.1 5.9e-58 195.7 17.4 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AET40698.1 - 1.2e-29 102.7 0.0 6.8e-29 100.2 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AET40698.1 - 1.8e-11 44.5 26.3 4.6e-08 33.3 0.6 4.1 2 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 AET40698.1 - 0.0057 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SAD_SRA PF02182.12 AET40698.1 - 0.11 11.8 3.8 0.49 9.6 0.0 3.3 3 0 0 3 3 3 0 SAD/SRA domain AAA_23 PF13476.1 AET40698.1 - 2.9 8.1 131.3 0.013 15.8 37.6 7.1 2 2 2 4 4 4 0 AAA domain Cytokin_check_N PF10407.4 AET40699.1 - 3.7e-32 109.7 2.3 8.7e-32 108.5 1.6 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.21 AET40701.1 - 1.3e-20 74.0 1.6 2.5e-20 73.2 1.1 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CytochromB561_N PF09786.4 AET40701.1 - 0.29 9.5 21.4 0.35 9.2 14.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF605 PF04652.11 AET40701.1 - 5.2 6.3 45.1 9.3 5.5 31.3 1.3 1 0 0 1 1 1 0 Vta1 like CAP PF00188.21 AET40702.1 - 1.9e-21 76.8 8.3 2.7e-21 76.3 5.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family KH_1 PF00013.24 AET40703.1 - 1.4e-66 220.0 33.4 8.5e-11 41.3 1.3 12.6 12 1 0 12 12 12 9 KH domain KH_3 PF13014.1 AET40703.1 - 2.2e-34 116.5 30.5 1.4e-06 27.7 1.0 10.9 10 0 0 10 10 10 7 KH domain KH_2 PF07650.12 AET40703.1 - 1.9e-08 33.7 20.6 0.024 14.2 0.2 6.8 5 1 1 6 6 6 5 KH domain KH_4 PF13083.1 AET40703.1 - 0.00015 21.3 7.4 0.52 9.9 0.0 6.1 6 0 0 6 6 6 1 KH domain KH_5 PF13184.1 AET40703.1 - 0.049 13.4 9.9 0.92 9.3 0.0 6.8 7 0 0 7 7 7 0 NusA-like KH domain Ras PF00071.17 AET40704.1 - 3.4e-54 182.5 0.3 4e-54 182.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET40704.1 - 1.4e-20 73.9 0.6 1.9e-20 73.5 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AET40704.1 - 1.2e-15 57.2 0.1 1.5e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET40704.1 - 1.3e-07 31.0 0.1 1.7e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AET40704.1 - 2.9e-05 24.0 0.0 4.6e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AET40704.1 - 6.7e-05 22.4 0.1 0.00015 21.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 AET40704.1 - 0.0082 14.8 0.5 2.8 6.5 0.0 2.9 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.1 AET40704.1 - 0.057 13.3 0.2 0.15 11.9 0.0 1.8 1 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 AET40704.1 - 0.083 12.0 0.2 0.15 11.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AET40704.1 - 0.13 12.0 0.4 3.9 7.2 0.1 2.4 1 1 1 2 2 2 0 Dynamin family Mitofilin PF09731.4 AET40705.1 - 5.2e-107 358.8 30.3 1e-91 308.4 20.9 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF365 PF04033.7 AET40705.1 - 0.75 9.8 4.8 3.8 7.5 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF365) IZUMO PF15005.1 AET40705.1 - 7.4 6.5 10.9 13 5.7 3.6 3.0 2 1 0 3 3 3 0 Izumo sperm-egg fusion Actin PF00022.14 AET40706.1 - 8.3e-94 314.2 0.0 3.5e-93 312.1 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AET40706.1 - 0.098 11.2 0.0 1.2 7.6 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein IBR PF01485.16 AET40707.1 - 4.7e-17 61.6 42.6 4.4e-10 39.2 8.2 3.9 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 AET40707.1 - 0.0001 21.8 13.8 0.0001 21.8 9.6 4.7 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET40707.1 - 0.00079 19.3 12.6 0.00079 19.3 8.7 4.7 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET40707.1 - 0.0092 15.7 10.5 0.0092 15.7 7.3 4.3 2 1 2 4 4 4 1 Ring finger domain DUF3808 PF10300.4 AET40708.1 - 3.2e-112 375.4 0.0 3.8e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) EF-hand_4 PF12763.2 AET40709.1 - 7.4e-06 25.6 0.1 2.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 AET40709.1 - 0.025 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Vps51 PF08700.6 AET40710.1 - 9.3e-11 41.4 5.4 4.1e-10 39.3 0.7 2.1 2 0 0 2 2 2 1 Vps51/Vps67 DUF3328 PF11807.3 AET40710.1 - 0.047 13.3 0.7 0.052 13.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Rsm22 PF09243.5 AET40710.1 - 0.12 11.4 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Striatin PF08232.7 AET40710.1 - 0.15 12.3 2.5 0.23 11.7 1.8 1.4 1 0 0 1 1 1 0 Striatin family PBP_sp32 PF07222.7 AET40710.1 - 0.36 9.9 2.3 0.45 9.6 1.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Arrestin_C PF02752.17 AET40711.1 - 1.7e-15 57.2 1.3 3.6e-14 53.0 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AET40711.1 - 1.5e-08 34.6 0.0 2.8e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Exo70 PF03081.10 AET40712.1 - 2.7e-84 283.1 3.0 2.7e-84 283.1 2.1 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit RNA_lig_T4_1 PF09511.5 AET40713.1 - 1.2e-78 263.6 2.0 1.5e-78 263.3 0.2 2.0 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 AET40713.1 - 3.4e-71 238.5 1.1 6.7e-71 237.5 0.8 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 AET40713.1 - 4.1e-49 167.1 0.1 7.6e-49 166.2 0.1 1.5 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.1 AET40713.1 - 0.0022 18.3 0.2 0.011 16.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AET40713.1 - 0.0029 17.9 0.0 0.0071 16.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter PRK PF00485.13 AET40713.1 - 0.011 15.3 0.1 0.037 13.6 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 AET40713.1 - 0.013 15.1 0.0 0.037 13.6 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein OTCace PF00185.19 AET40714.1 - 2.1e-43 147.9 0.9 3.3e-43 147.2 0.6 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 AET40714.1 - 1.6e-40 138.0 0.2 1.9e-39 134.5 0.0 2.1 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain NTR2 PF15458.1 AET40715.1 - 1.4e-34 119.5 19.9 1.4e-34 119.5 13.8 2.1 1 1 1 2 2 2 2 Nineteen complex-related protein 2 Zn_clus PF00172.13 AET40716.1 - 5e-10 39.1 11.9 8.3e-10 38.4 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRCT PF00533.21 AET40717.1 - 1.9e-15 56.7 0.7 0.0039 17.3 0.0 4.3 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AET40717.1 - 7.7e-09 35.2 1.6 0.0024 17.6 0.0 4.0 4 0 0 4 4 4 2 twin BRCT domain GWT1 PF06423.7 AET40718.1 - 2.9e-44 150.4 4.3 2.9e-44 150.4 3.0 2.1 2 0 0 2 2 2 1 GWT1 UvrD_C PF13361.1 AET40719.1 - 2.2e-65 221.4 1.3 2.5e-41 142.3 0.8 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 AET40719.1 - 1.1e-61 208.8 0.0 1.1e-61 208.8 0.0 3.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 AET40719.1 - 7e-08 32.5 0.0 0.00064 19.8 0.0 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 AET40719.1 - 8.6e-08 31.8 0.0 1.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AET40719.1 - 0.011 15.2 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 AET40720.1 - 9.7e-66 221.5 0.0 2.4e-65 220.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40720.1 - 1.7e-43 148.6 0.0 3.1e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET40720.1 - 1.1e-08 34.3 0.0 8.1e-06 24.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AET40720.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L21p PF00829.16 AET40721.1 - 7.8e-06 25.9 0.0 1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PTPLA PF04387.9 AET40722.1 - 2.4e-44 150.6 9.4 2.4e-44 150.6 6.5 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA SAPS PF04499.10 AET40723.1 - 1.1e-175 584.8 0.1 1.1e-175 584.8 0.1 3.1 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein ChAPs PF09295.5 AET40724.1 - 3.2e-53 180.9 1.0 1.7e-43 148.9 0.1 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 AET40724.1 - 1.6e-11 43.6 1.6 9.9e-10 37.9 0.3 2.4 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 AET40724.1 - 1.1e-07 32.0 0.6 3.9e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 AET40724.1 - 5e-07 29.1 6.2 0.0025 17.6 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AET40724.1 - 6.6e-07 29.3 0.8 4.8e-05 23.4 0.1 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AET40724.1 - 2.7e-05 23.9 0.3 0.0024 17.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AET40724.1 - 4.4e-05 22.9 5.5 0.0002 20.8 0.6 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AET40724.1 - 6e-05 22.5 3.2 0.0014 18.2 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AET40724.1 - 0.00023 21.0 3.1 0.00083 19.2 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 AET40724.1 - 0.00037 20.4 2.4 0.0005 20.0 0.3 2.4 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 AET40724.1 - 0.00071 20.1 0.2 0.0031 18.1 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 AET40724.1 - 0.031 14.7 0.2 0.11 12.9 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 AET40724.1 - 0.28 11.9 2.5 1.1 10.0 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 AET40724.1 - 2.4 8.1 4.2 8.1 6.5 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.22 AET40725.1 - 7.4e-58 195.7 0.1 1.1e-57 195.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GCS PF03074.11 AET40726.1 - 4.4e-132 440.6 0.2 5.5e-132 440.2 0.1 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GTP_EFTU PF00009.22 AET40727.1 - 1.9e-56 190.4 0.1 3.8e-56 189.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 AET40727.1 - 1.5e-28 98.4 0.0 1.6e-27 95.1 0.0 2.5 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 AET40727.1 - 4e-16 58.6 0.1 9.8e-15 54.1 0.1 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AET40727.1 - 3.8e-09 36.5 0.1 1e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Abhydro_lipase PF04083.11 AET40727.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region IF-2B PF01008.12 AET40728.1 - 1.6e-70 237.3 0.0 1.8e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Sin_N PF04801.8 AET40729.1 - 2.1e-16 59.7 0.5 3.1e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region PGA2 PF07543.7 AET40729.1 - 0.066 13.0 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DEAD PF00270.24 AET40730.1 - 1.9e-37 128.3 0.0 3.7e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET40730.1 - 5.1e-19 67.9 0.0 1.2e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AET40730.1 - 1.9e-17 62.5 0.1 4.4e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AET40730.1 - 0.016 15.0 0.2 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zn_clus PF00172.13 AET40731.1 - 4.3e-07 29.7 10.7 7.9e-07 28.8 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 AET40731.1 - 4.3e-05 23.2 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 AET40731.1 - 0.019 15.3 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.1 AET40731.1 - 0.14 12.0 0.1 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 PAS domain zf-C2HC5 PF06221.8 AET40732.1 - 5.2e-20 70.9 9.0 8.8e-20 70.2 6.2 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.1 AET40732.1 - 2.3 7.5 7.9 4.6 6.5 5.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Apis_Csd PF11671.3 AET40732.1 - 3.3 7.5 9.8 9.2 6.0 2.9 2.8 3 0 0 3 3 3 0 Complementary sex determiner protein FmdE PF02663.9 AET40732.1 - 7.9 6.3 8.0 0.78 9.6 0.3 3.0 4 0 0 4 4 4 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Pam16 PF03656.8 AET40733.1 - 9.2e-45 151.5 0.6 9.9e-45 151.4 0.4 1.0 1 0 0 1 1 1 1 Pam16 SET PF00856.23 AET40734.1 - 6e-10 39.6 0.1 6e-10 39.6 0.1 2.5 3 0 0 3 3 3 1 SET domain PHD PF00628.24 AET40734.1 - 6.5e-10 38.5 9.8 1.5e-09 37.3 6.8 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 AET40734.1 - 0.0017 17.6 4.9 0.0038 16.5 3.4 1.6 1 0 0 1 1 1 1 PHD-finger Chorion_2 PF03964.10 AET40734.1 - 0.0095 16.4 9.0 0.17 12.4 1.1 2.8 2 0 0 2 2 2 2 Chorion family 2 zf-CW PF07496.10 AET40734.1 - 0.055 13.1 0.9 0.15 11.7 0.7 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger Pkinase PF00069.20 AET40735.1 - 4.8e-54 183.2 0.1 5.4e-52 176.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AET40735.1 - 4.6e-27 94.7 0.2 2.3e-26 92.4 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 AET40735.1 - 0.017 14.1 0.1 0.032 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1212 PF06738.7 AET40736.1 - 1.2e-49 168.4 15.9 2.4e-45 154.3 0.4 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 AET40736.1 - 3e-26 91.8 9.7 3e-26 91.8 6.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Peptidase_A8 PF01252.13 AET40736.1 - 0.53 9.8 5.3 0.1 12.1 0.4 2.0 2 1 0 2 2 2 0 Signal peptidase (SPase) II Ribosomal_60s PF00428.14 AET40736.1 - 1.2 9.5 12.1 0.03 14.7 3.3 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein BP28CT PF08146.7 AET40737.1 - 2.1e-43 147.6 4.7 1.3e-42 145.0 3.3 2.6 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 AET40737.1 - 1.6e-20 73.2 3.0 1.6e-20 73.2 2.1 3.9 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 AET40737.1 - 0.00064 19.9 1.4 4.5 7.6 0.0 4.9 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.17 AET40737.1 - 0.0023 17.8 0.4 3.6 7.9 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 AET40737.1 - 0.37 11.3 6.4 1.6 9.3 0.2 4.6 4 1 1 5 5 5 0 HEAT-like repeat UNC-50 PF05216.8 AET40738.1 - 4.1e-89 297.7 19.3 4.6e-89 297.5 13.4 1.0 1 0 0 1 1 1 1 UNC-50 family PLDc PF00614.17 AET40740.1 - 9.9e-17 60.1 4.4 1.2e-08 34.4 0.3 3.7 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 AET40740.1 - 5.3e-12 45.5 1.8 3.6e-08 33.1 0.2 4.5 3 1 1 4 4 4 2 PLD-like domain PX PF00787.19 AET40740.1 - 2.4e-06 27.3 2.7 0.015 15.0 0.2 3.5 3 0 0 3 3 3 2 PX domain GATA PF00320.22 AET40741.1 - 8.1e-15 53.8 3.3 1.5e-14 53.0 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 AET40741.1 - 0.0084 15.4 0.3 0.017 14.4 0.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Snf7 PF03357.16 AET40742.1 - 1.6e-15 56.8 19.6 1.6e-15 56.8 13.6 1.3 1 1 0 1 1 1 1 Snf7 DUF1049 PF06305.6 AET40742.1 - 0.27 10.7 1.6 0.95 8.9 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) H-kinase_dim PF02895.9 AET40742.1 - 0.79 10.0 13.1 0.37 11.1 0.4 3.5 2 2 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain APG6 PF04111.7 AET40742.1 - 1.2 8.1 13.7 1.3 7.9 2.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF244 PF03112.9 AET40742.1 - 1.2 8.6 8.0 0.057 12.9 1.2 2.0 2 1 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF DUF948 PF06103.6 AET40742.1 - 3.4 7.5 11.6 0.25 11.2 0.6 3.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Cpn60_TCP1 PF00118.19 AET40743.1 - 3.4e-148 494.2 4.8 3.9e-148 494.0 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dak2 PF02734.12 AET40743.1 - 0.056 13.1 0.7 0.7 9.5 0.0 2.6 2 1 0 2 2 2 0 DAK2 domain ADH_zinc_N PF00107.21 AET40744.1 - 1.4e-11 44.0 0.0 2.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AET40744.1 - 4.9e-06 26.2 0.1 3e-05 23.7 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AET40744.1 - 0.099 13.5 0.0 0.3 11.9 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PIR PF00399.14 AET40745.1 - 1.4e-06 27.4 8.7 2.2e-06 26.8 5.4 1.9 1 1 0 1 1 1 1 Yeast PIR protein repeat FKBP_C PF00254.23 AET40747.1 - 2.1e-32 110.9 0.0 2.5e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Eaf7 PF07904.8 AET40748.1 - 4.3e-29 100.3 0.1 4.3e-29 100.3 0.1 2.3 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 SDA1 PF05285.7 AET40748.1 - 8.2e-08 31.8 5.2 1.6e-07 30.9 3.6 1.5 1 1 0 1 1 1 1 SDA1 TFIIF_alpha PF05793.7 AET40748.1 - 0.059 11.7 28.9 0.082 11.2 20.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4611 PF15387.1 AET40748.1 - 3.9 7.6 24.7 0.85 9.8 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 AET40748.1 - 7.2 6.1 26.8 10 5.5 0.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin S4 PF01479.20 AET40749.1 - 1.5e-17 62.7 0.0 3.1e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 AET40749.1 - 0.00017 21.0 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain FHA PF00498.21 AET40749.1 - 0.024 14.7 0.0 0.6 10.2 0.0 2.4 2 0 0 2 2 2 0 FHA domain CAP_N PF01213.14 AET40750.1 - 8.2e-96 320.9 0.5 1.1e-95 320.5 0.3 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 AET40750.1 - 2e-59 199.5 4.0 2.7e-59 199.0 2.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 AET40750.1 - 0.58 9.5 3.6 1.2 8.5 2.5 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C SF3b10 PF07189.6 AET40752.1 - 8.7e-25 86.3 0.6 1e-24 86.1 0.4 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Tho2 PF11262.3 AET40753.1 - 3.9e-54 183.7 7.4 3.9e-54 183.7 5.2 3.4 2 2 1 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 AET40753.1 - 5.1e-23 80.6 0.1 1.6e-22 79.0 0.1 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit C2 PF00168.25 AET40754.1 - 2.1e-10 40.3 0.0 3.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain RNA_pol_3_Rpc31 PF11705.3 AET40755.1 - 6.4e-61 206.2 15.5 7.1e-61 206.1 10.7 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PTPA PF03095.10 AET40755.1 - 0.066 12.3 0.0 0.12 11.5 0.0 1.4 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein Cwf_Cwc_15 PF04889.7 AET40755.1 - 0.21 11.2 9.7 0.3 10.7 6.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGA2 PF07543.7 AET40756.1 - 8.3e-13 48.3 8.7 1.1e-10 41.4 6.0 2.0 1 1 0 1 1 1 1 Protein trafficking PGA2 BTV_NS2 PF04514.7 AET40756.1 - 0.023 13.5 1.7 0.028 13.3 1.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DNA_primase_lrg PF04104.9 AET40756.1 - 0.085 12.1 1.0 0.19 11.0 0.6 1.5 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit DUF1049 PF06305.6 AET40756.1 - 0.78 9.2 0.0 0.78 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) CAP_GLY PF01302.20 AET40757.1 - 5.3e-19 67.6 1.1 9.5e-19 66.8 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 AET40757.1 - 0.00012 22.2 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain LSM PF01423.17 AET40758.1 - 1.1e-17 63.2 0.5 1.5e-17 62.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain UPRTase PF14681.1 AET40759.1 - 1.2e-75 253.2 0.0 1.6e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 AET40759.1 - 0.0075 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CoA_binding_2 PF13380.1 AET40759.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Flu_C_NS1 PF03506.8 AET40759.1 - 0.099 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.14 AET40760.1 - 9.6e-125 416.0 0.0 1.1e-124 415.8 0.0 1.0 1 0 0 1 1 1 1 Actin DUF2009 PF09418.5 AET40761.1 - 1.8e-218 725.9 0.2 2.1e-218 725.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 AET40761.1 - 0.00011 21.9 3.5 0.00022 21.0 2.4 1.5 1 0 0 1 1 1 1 B-box zinc finger DUF4021 PF13213.1 AET40762.1 - 0.05 13.2 0.0 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4021) Pga1 PF10333.4 AET40764.1 - 2.1e-54 183.8 0.4 2.6e-54 183.5 0.3 1.0 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Endosulfine PF04667.12 AET40765.1 - 8.5e-33 112.1 0.0 1.2e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.7 AET40766.1 - 2e-10 40.3 2.6 3.1e-10 39.7 1.8 1.3 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) WLM PF08325.5 AET40767.1 - 1.3e-48 165.3 0.1 1.9e-48 164.8 0.1 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 AET40767.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 zf-AN1 PF01428.11 AET40768.1 - 2.8e-12 46.3 9.3 4.2e-12 45.7 6.5 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Prefoldin_2 PF01920.15 AET40770.1 - 1e-19 70.2 12.2 1.2e-19 69.9 8.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Imm7 PF15588.1 AET40770.1 - 0.055 13.5 0.4 0.055 13.5 0.3 1.9 1 1 0 2 2 2 0 Immunity protein 7 PspB PF06667.7 AET40770.1 - 0.22 11.5 2.6 0.49 10.3 0.2 2.5 2 1 1 3 3 3 0 Phage shock protein B DUF4140 PF13600.1 AET40770.1 - 1.4 9.4 9.0 0.48 10.8 1.8 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 AET40770.1 - 2.1 7.9 8.5 0.69 9.4 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator FTA4 PF13093.1 AET40770.1 - 3.1 7.1 8.9 0.56 9.6 2.6 1.8 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Lge1 PF11488.3 AET40770.1 - 4.9 7.4 6.4 8.6 6.6 1.5 2.2 1 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF4164 PF13747.1 AET40770.1 - 7.8 6.7 12.0 33 4.7 2.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Ammonium_transp PF00909.16 AET40772.1 - 9.2e-124 412.9 26.6 1.1e-123 412.7 18.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Far-17a_AIG1 PF04750.9 AET40773.1 - 8e-17 61.0 7.1 9.8e-17 60.7 4.9 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pkinase PF00069.20 AET40774.1 - 6.9e-58 195.8 4.9 8.5e-40 136.5 0.1 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 AET40774.1 - 3e-26 92.0 2.1 4.3e-20 71.8 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AET40774.1 - 0.0013 17.7 0.0 0.007 15.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 AET40774.1 - 0.0014 19.1 0.1 0.0058 17.1 0.1 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 AET40774.1 - 0.0041 16.1 0.4 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AET40774.1 - 0.041 12.7 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 AET40774.1 - 0.069 12.8 3.6 0.83 9.3 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AET40774.1 - 0.075 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BAF1_ABF1 PF04684.8 AET40774.1 - 3.5 6.3 30.7 3.3 6.4 6.0 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_L44 PF00935.14 AET40775.1 - 4.5e-33 113.0 12.7 6.9e-33 112.4 8.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DUF2652 PF10851.3 AET40775.1 - 3.2 7.7 5.7 0.71 9.8 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2652) Chs3p PF12271.3 AET40776.1 - 6e-83 278.2 20.8 1.6e-82 276.8 14.4 1.5 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit Lar_restr_allev PF14354.1 AET40777.1 - 0.029 14.6 0.6 0.036 14.3 0.4 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-TRAF PF02176.13 AET40777.1 - 0.056 13.8 2.5 0.12 12.8 0.1 2.0 1 1 1 2 2 2 0 TRAF-type zinc finger UPF1_Zn_bind PF09416.5 AET40777.1 - 0.068 12.7 0.6 0.081 12.4 0.4 1.1 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) Zn-ribbon_8 PF09723.5 AET40777.1 - 0.88 9.5 3.6 0.29 11.1 0.5 1.7 2 0 0 2 2 2 0 Zinc ribbon domain GTP_EFTU PF00009.22 AET40778.1 - 1.2e-53 181.3 0.0 2.2e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AET40778.1 - 2e-15 56.4 0.1 1e-14 54.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AET40778.1 - 1e-10 41.5 0.0 2.8e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AET40778.1 - 3.7e-08 33.0 0.0 9.9e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 AET40778.1 - 7.1e-05 22.3 0.0 0.0006 19.3 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV DNA_RNApol_7kD PF03604.8 AET40782.1 - 8.3e-17 60.3 1.9 1.1e-16 60.0 1.3 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 AET40782.1 - 0.00089 19.0 0.5 0.0012 18.5 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 AET40782.1 - 0.0027 17.3 0.2 0.0028 17.3 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 AET40782.1 - 0.0037 16.8 1.0 1.6 8.4 0.1 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Prok-RING_1 PF14446.1 AET40782.1 - 0.0098 15.6 0.5 0.013 15.2 0.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 FYDLN_acid PF09538.5 AET40782.1 - 0.018 15.6 0.4 0.021 15.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NCD3G PF07562.9 AET40782.1 - 0.021 14.5 0.2 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DUF951 PF06107.6 AET40782.1 - 0.024 14.1 1.8 0.53 9.8 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF2318 PF10080.4 AET40782.1 - 0.026 14.2 0.1 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF2296 PF10058.4 AET40782.1 - 0.03 14.0 0.4 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) C1_1 PF00130.17 AET40782.1 - 0.036 13.7 0.6 0.053 13.2 0.4 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 AET40782.1 - 0.046 12.9 0.3 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 AET40782.1 - 0.069 12.6 1.0 0.93 9.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Ogr_Delta PF04606.7 AET40782.1 - 0.1 12.2 0.9 7.2 6.3 0.1 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger OrfB_Zn_ribbon PF07282.6 AET40782.1 - 0.11 12.1 0.8 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2197 PF09963.4 AET40782.1 - 0.12 12.3 2.5 7.2 6.6 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-AN1 PF01428.11 AET40782.1 - 0.13 12.1 1.0 0.26 11.1 0.7 1.4 1 1 0 1 1 1 0 AN1-like Zinc finger Herpes_UL33 PF03581.8 AET40782.1 - 0.14 12.0 0.2 0.17 11.7 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL33-like protein DUF4428 PF14471.1 AET40782.1 - 0.2 11.4 1.7 1.5 8.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) zf-ISL3 PF14690.1 AET40782.1 - 0.27 11.3 1.9 0.41 10.7 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TF_Zn_Ribbon PF08271.7 AET40782.1 - 0.28 10.5 3.2 5.7 6.3 0.3 2.1 1 1 2 3 3 3 0 TFIIB zinc-binding Ribosomal_L40e PF01020.12 AET40782.1 - 0.29 10.7 3.1 0.37 10.4 2.1 1.2 1 0 0 1 1 1 0 Ribosomal L40e family Zn-ribbon_8 PF09723.5 AET40782.1 - 0.33 10.9 2.9 1.1 9.3 2.0 1.8 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 AET40782.1 - 0.37 10.4 4.3 2.1 7.9 3.0 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 AET40782.1 - 0.41 10.9 4.2 4.5 7.6 0.8 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 AET40782.1 - 0.45 10.3 3.7 2.6 7.9 0.3 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 AET40782.1 - 0.48 10.1 4.6 3 7.6 3.2 2.2 1 1 0 1 1 1 0 zinc-ribbon domain bZIP_1 PF00170.16 AET40783.1 - 6.9e-08 32.3 4.8 1.8e-07 31.0 3.3 1.7 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 AET40783.1 - 3.7e-07 30.5 0.3 3.7e-07 30.5 0.2 2.5 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 AET40783.1 - 5.4e-05 22.9 5.5 0.00018 21.2 3.8 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Macoilin PF09726.4 AET40783.1 - 7.1 4.7 19.0 1.7 6.8 10.8 1.5 1 1 0 1 1 1 0 Transmembrane protein dCMP_cyt_deam_1 PF00383.17 AET40784.1 - 4.7e-26 90.3 1.0 6.8e-26 89.8 0.7 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 AET40784.1 - 0.077 12.7 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase P68HR PF08061.6 AET40784.1 - 5.2 6.8 5.9 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 P68HR (NUC004) repeat PS_Dcarbxylase PF02666.10 AET40785.1 - 1e-76 256.7 0.0 9.8e-76 253.5 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase PFO_beta_C PF12367.3 AET40785.1 - 0.079 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Apc1 PF12859.2 AET40786.1 - 2.3e-11 43.8 0.3 2.3e-11 43.8 0.2 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 RRM_1 PF00076.17 AET40788.1 - 1.1e-24 85.8 0.2 4.8e-16 58.1 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET40788.1 - 3.6e-17 62.0 0.1 2.3e-09 37.1 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET40788.1 - 4e-08 32.9 0.2 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AET40788.1 - 0.014 15.1 0.1 0.073 12.8 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Syndecan PF01034.15 AET40789.1 - 0.083 12.5 0.2 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Ribosomal_L22 PF00237.14 AET40790.1 - 1.8e-18 66.4 0.0 2.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SHR3_chaperone PF08229.6 AET40791.1 - 8.7e-79 263.0 1.6 1e-78 262.8 1.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.1 AET40791.1 - 0.11 12.8 0.1 3 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF2648 PF10855.3 AET40791.1 - 0.4 10.1 0.0 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) Ribosomal_S3_C PF00189.15 AET40792.1 - 3.4e-16 59.2 0.1 6.9e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 AET40792.1 - 7.9e-12 44.5 0.0 3.1e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 KH domain Ras PF00071.17 AET40793.1 - 4.4e-45 152.9 0.0 6.1e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET40793.1 - 1.4e-14 54.5 0.0 5.9e-14 52.5 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET40793.1 - 8.3e-07 28.4 0.0 1.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AET40793.1 - 0.00047 19.6 0.0 0.0029 17.0 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AET40793.1 - 0.048 12.7 0.0 0.096 11.8 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AET40793.1 - 0.05 13.5 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase adh_short PF00106.20 AET40794.1 - 1.3e-07 31.7 0.0 3.4e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AET40794.1 - 6.2e-06 25.9 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 AET40795.1 - 5e-06 26.2 0.4 0.12 12.3 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat IKI3 PF04762.7 AET40795.1 - 0.015 13.1 0.0 0.039 11.7 0.0 1.6 2 0 0 2 2 2 0 IKI3 family CPSF_A PF03178.10 AET40795.1 - 0.018 14.1 0.0 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 CPSF A subunit region RRM_1 PF00076.17 AET40796.1 - 6.7e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET40796.1 - 1e-05 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP-synt_E PF05680.7 AET40796.1 - 2 8.4 12.9 9.5 6.2 0.1 2.2 2 0 0 2 2 2 0 ATP synthase E chain DUF3513 PF12026.3 AET40796.1 - 9.5 5.7 12.7 1.5 8.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) Pkinase PF00069.20 AET40797.1 - 3.7e-62 209.8 0.0 5.4e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET40797.1 - 1.2e-22 80.1 0.0 2e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L11_N PF03946.9 AET40798.1 - 2.4e-28 97.3 0.2 4.1e-28 96.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AET40798.1 - 1.8e-27 95.2 0.7 2.8e-27 94.6 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain JAB PF01398.16 AET40799.1 - 4.8e-27 93.9 0.1 2.5e-26 91.6 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 AET40799.1 - 5.8e-06 25.8 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 AET40799.1 - 0.011 15.1 0.2 0.04 13.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Tim17 PF02466.14 AET40801.1 - 1.7e-48 163.8 4.1 2.2e-48 163.5 2.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 AET40801.1 - 0.17 11.1 1.6 0.55 9.4 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family Gly-zipper_Omp PF13488.1 AET40801.1 - 0.86 9.2 7.5 0.25 11.0 0.6 2.3 2 0 0 2 2 2 0 Glycine zipper CCDC-167 PF15188.1 AET40802.1 - 2.4 8.1 6.5 1.7 8.6 0.1 2.6 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Arm PF00514.18 AET40803.1 - 2.6e-87 284.0 14.1 5.6e-14 51.3 0.2 8.8 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 AET40803.1 - 9.2e-25 86.6 8.4 2.2e-24 85.4 5.8 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 AET40803.1 - 1.7e-21 76.2 0.1 2.8e-06 27.4 0.0 5.6 1 1 6 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 AET40803.1 - 3.4e-19 68.7 3.4 2.6e-05 24.5 0.0 5.9 4 2 3 7 7 7 3 HEAT-like repeat HEAT PF02985.17 AET40803.1 - 1.1e-12 46.8 1.3 0.014 15.3 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.8 AET40803.1 - 4.7e-07 29.1 0.9 1.1 8.2 0.1 4.4 2 1 2 5 5 5 5 Armadillo-like Adaptin_N PF01602.15 AET40803.1 - 3.9e-05 22.1 1.3 0.0033 15.7 0.4 2.8 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 AET40803.1 - 0.00012 21.9 0.2 1.5 8.7 0.0 4.4 2 1 4 6 6 6 2 V-ATPase subunit H RICTOR_V PF14668.1 AET40803.1 - 0.00016 21.5 4.2 3.7 7.5 0.0 5.4 2 2 5 7 7 7 3 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 AET40803.1 - 0.0011 17.3 1.7 0.0062 14.8 0.1 2.5 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit FAST_1 PF06743.10 AET40803.1 - 0.017 14.8 1.4 0.54 10.0 0.0 3.2 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 GATase_4 PF13230.1 AET40805.1 - 4.5e-19 68.1 0.1 3.9e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AET40805.1 - 2.7e-11 43.5 0.0 6.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AET40805.1 - 8.2e-10 37.9 0.1 1.6e-07 30.3 0.1 2.2 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 AET40805.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 1 0 1 1 1 0 Glutamine amidotransferase domain Tyr_Deacylase PF02580.11 AET40806.1 - 4.6e-45 153.1 0.1 5.1e-45 153.0 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Ubiquitin_3 PF14836.1 AET40806.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Chitin_synth_1 PF01644.12 AET40807.1 - 1.9e-75 252.1 0.1 2.9e-75 251.5 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 AET40807.1 - 2.3e-27 94.4 0.1 5.9e-27 93.1 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 AET40807.1 - 2e-17 62.8 6.7 9.7e-15 53.9 0.6 2.5 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 AET40807.1 - 3e-11 43.4 5.9 3e-11 43.4 4.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AET40807.1 - 8.8e-09 35.4 0.0 6.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AET40807.1 - 0.0012 18.5 0.0 0.23 11.1 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Hexokinase_2 PF03727.11 AET40808.1 - 0.57 9.3 2.9 0.83 8.7 0.3 2.2 2 1 0 2 2 2 0 Hexokinase POT1 PF02765.12 AET40809.1 - 1.2e-12 47.9 1.0 3.5e-12 46.4 0.7 1.8 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 DUF3888 PF13027.1 AET40809.1 - 0.0085 15.9 1.0 0.66 9.8 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3888) SUR7 PF06687.7 AET40810.1 - 4e-33 114.7 6.5 5.6e-33 114.2 4.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 AET40810.1 - 0.0016 18.1 4.4 0.0016 18.1 3.0 1.9 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_3 PF12698.2 AET40810.1 - 2.9 6.8 13.2 10 5.0 9.2 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein Fig1 PF12351.3 AET40810.1 - 8.7 6.1 7.3 18 5.1 5.1 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 MARVEL PF01284.18 AET40810.1 - 9.7 5.9 15.0 0.68 9.7 6.4 1.9 2 1 0 2 2 2 0 Membrane-associating domain RRM_1 PF00076.17 AET40812.1 - 8.9e-17 60.4 0.0 2.2e-15 56.0 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET40812.1 - 2.2e-09 37.1 0.0 1.1e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mem_trans PF03547.13 AET40812.1 - 0.29 9.3 11.8 0.019 13.3 4.1 1.8 2 0 0 2 2 2 0 Membrane transport protein DUF4175 PF13779.1 AET40812.1 - 0.31 8.6 51.0 0.45 8.1 35.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SLD3 PF08639.5 AET40812.1 - 1.1 7.7 34.1 1.9 7.0 22.2 2.0 2 0 0 2 2 2 0 DNA replication regulator SLD3 Tim54 PF11711.3 AET40812.1 - 1.9 7.0 12.6 2.9 6.4 8.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pneumo_phosprot PF02478.11 AET40812.1 - 2.5 7.5 9.1 5.2 6.5 6.3 1.5 1 0 0 1 1 1 0 Pneumovirus phosphoprotein eIF-3_zeta PF05091.7 AET40812.1 - 2.7 6.5 23.6 4.1 5.9 16.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 AET40812.1 - 3.9 7.2 18.9 7.3 6.3 13.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 AET40812.1 - 6.4 4.3 17.7 9 3.8 12.3 1.1 1 0 0 1 1 1 0 Ycf1 Baculo_PP31 PF05311.6 AET40812.1 - 6.5 5.9 20.2 13 4.9 14.0 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FLO_LFY PF01698.11 AET40812.1 - 7.4 5.3 16.0 52 2.5 11.9 1.7 2 0 0 2 2 2 0 Floricaula / Leafy protein Septin PF00735.13 AET40813.1 - 1.8e-76 256.8 2.8 5.9e-76 255.1 0.2 2.6 2 1 0 2 2 2 1 Septin AAA_17 PF13207.1 AET40813.1 - 8.4e-05 23.3 0.5 0.0013 19.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AET40813.1 - 0.00012 21.9 0.3 0.00042 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AET40813.1 - 0.0007 19.7 1.5 0.0043 17.1 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 AET40813.1 - 0.0016 18.4 0.5 0.0089 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 AET40813.1 - 0.002 18.0 0.0 0.0075 16.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 AET40813.1 - 0.0028 16.8 2.1 0.0034 16.5 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_5 PF07728.9 AET40813.1 - 0.0029 17.3 0.0 0.0074 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 AET40813.1 - 0.0032 16.9 0.0 0.0096 15.4 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.1 AET40813.1 - 0.0033 17.0 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AET40813.1 - 0.0037 17.5 0.5 0.01 16.1 0.0 2.2 2 1 0 2 2 1 1 AAA domain GTP_EFTU PF00009.22 AET40813.1 - 0.004 16.6 0.5 0.019 14.4 0.0 2.3 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA PF00004.24 AET40813.1 - 0.004 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 AET40813.1 - 0.0074 16.1 0.5 0.063 13.0 0.0 2.6 3 0 0 3 3 3 1 Dynamin family DUF258 PF03193.11 AET40813.1 - 0.0081 15.3 0.0 0.021 13.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 AET40813.1 - 0.013 15.0 0.1 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 AET40813.1 - 0.014 15.5 0.0 0.051 13.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.16 AET40813.1 - 0.02 14.0 0.0 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 AET40813.1 - 0.035 13.5 0.1 0.071 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain MobB PF03205.9 AET40813.1 - 0.036 13.7 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 AET40813.1 - 0.045 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein IstB_IS21 PF01695.12 AET40813.1 - 0.047 13.1 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 AET40813.1 - 0.048 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_32 PF13654.1 AET40813.1 - 0.057 12.0 4.2 1.6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 AET40813.1 - 0.067 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 AET40813.1 - 0.07 13.0 1.0 0.11 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 AET40813.1 - 0.073 12.4 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AET40813.1 - 0.09 12.3 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 AET40813.1 - 0.21 11.9 0.1 0.21 11.9 0.1 2.5 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 AET40813.1 - 3.1 8.0 16.2 2.3 8.5 0.0 2.6 2 1 0 3 3 2 0 AAA domain KLRAQ PF10205.4 AET40814.1 - 0.024 14.6 0.4 0.069 13.1 0.3 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein YjeF_N PF03853.10 AET40815.1 - 8.4e-38 129.6 0.0 1e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SMK-1 PF04802.10 AET40816.1 - 9.7e-64 214.4 5.4 9.7e-64 214.4 3.7 2.4 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 AET40816.1 - 0.0012 18.5 0.0 0.003 17.2 0.0 1.7 1 0 0 1 1 1 1 WH1 domain Zip PF02535.17 AET40816.1 - 5.5 5.8 6.2 9.2 5.1 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter adh_short_C2 PF13561.1 AET40817.1 - 7.1e-30 104.5 0.3 9.1e-30 104.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AET40817.1 - 1.5e-20 73.7 5.0 2.6e-20 72.9 3.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AET40817.1 - 9.9e-11 41.6 2.1 1.6e-10 40.9 1.5 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 AET40817.1 - 0.046 12.8 0.0 0.089 11.9 0.0 1.4 1 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) ArfGap PF01412.13 AET40818.1 - 8.3e-33 112.6 0.0 2e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Rtt106 PF08512.7 AET40819.1 - 2e-28 98.2 1.0 2e-28 98.2 0.7 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like RIO1 PF01163.17 AET40820.1 - 4.4e-43 146.8 0.2 6.4e-43 146.3 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 AET40820.1 - 7.2e-31 106.0 0.2 1.6e-30 104.9 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 AET40820.1 - 8e-09 35.5 0.4 0.00013 21.8 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AET40820.1 - 0.00025 20.1 0.1 0.0081 15.2 0.0 2.5 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 AET40820.1 - 0.0093 15.1 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain VID27 PF08553.5 AET40822.1 - 2.1e-276 919.2 13.3 2.6e-276 918.9 9.2 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF2697 PF10906.3 AET40823.1 - 8.9e-26 89.6 0.5 1.1e-25 89.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) Ost4 PF10215.4 AET40824.1 - 3.7e-13 48.7 1.8 4.1e-13 48.5 1.3 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase FUSC_2 PF13515.1 AET40825.1 - 4.5e-06 26.6 5.1 4.5e-06 26.6 3.6 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 AET40825.1 - 1.7e-05 24.5 0.0 4.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC PF04632.7 AET40825.1 - 0.00015 20.3 2.9 0.51 8.6 1.6 3.2 2 1 1 3 3 3 3 Fusaric acid resistance protein family MSA-2c PF12238.3 AET40825.1 - 0.21 11.2 3.9 0.51 9.9 2.7 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Y_phosphatase PF00102.22 AET40826.1 - 3.4e-54 183.6 0.0 4.6e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 AET40826.1 - 0.00077 19.0 0.0 0.0019 17.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 AET40826.1 - 0.00097 19.4 0.0 0.0023 18.1 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 AET40826.1 - 0.0053 16.8 0.1 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate KH_1 PF00013.24 AET40827.1 - 4.2e-07 29.5 1.3 9.9e-07 28.3 0.1 2.0 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 AET40827.1 - 0.03 14.0 1.6 0.1 12.3 0.4 2.3 2 0 0 2 2 2 0 KH domain HSP70 PF00012.15 AET40828.1 - 1.5e-236 786.0 7.9 1.7e-236 785.9 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AET40828.1 - 1.7e-17 63.0 1.0 4.9e-16 58.2 0.3 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AET40828.1 - 0.00015 21.4 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain EAP30 PF04157.11 AET40828.1 - 0.015 14.4 0.8 0.03 13.4 0.5 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family Tombus_P19 PF03220.8 AET40828.1 - 0.06 12.6 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Tombusvirus P19 core protein Flagellin_N PF00669.15 AET40828.1 - 0.08 12.7 2.3 0.21 11.3 1.6 1.6 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Integrase_AP2 PF14657.1 AET40828.1 - 0.1 12.3 0.4 0.31 10.8 0.3 1.8 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain Neugrin PF06413.6 AET40829.1 - 8.4e-09 35.5 0.3 8.4e-09 35.5 0.2 1.5 2 0 0 2 2 2 1 Neugrin Sigma70_r4 PF04545.11 AET40829.1 - 0.0015 17.7 0.1 0.0031 16.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Mod_r PF07200.8 AET40829.1 - 0.01 15.7 2.4 0.014 15.2 1.7 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HTH_32 PF13565.1 AET40829.1 - 0.013 16.3 0.2 0.032 15.0 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Rota_NSP4 PF01452.11 AET40829.1 - 0.062 12.6 1.6 0.23 10.7 1.1 1.9 1 1 0 1 1 1 0 Rotavirus non structural protein HTH_11 PF08279.7 AET40829.1 - 0.1 12.2 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 HTH domain DUF3702 PF12486.3 AET40830.1 - 0.092 12.4 0.4 0.62 9.7 0.0 2.3 2 1 0 2 2 2 0 ImpA domain protein Z1 PF10593.4 AET40830.1 - 0.11 11.6 0.6 0.14 11.3 0.4 1.4 1 1 0 1 1 1 0 Z1 domain Baculo_11_kDa PF06143.6 AET40830.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Epsilon_antitox PF08998.6 AET40830.1 - 0.66 9.9 3.3 0.5 10.3 0.4 2.1 3 0 0 3 3 3 0 Bacterial epsilon antitoxin LIM_bind PF01803.11 AET40831.1 - 5.5e-59 199.1 0.0 5.5e-59 199.1 0.0 3.0 2 1 1 3 3 3 1 LIM-domain binding protein MCM_bind PF09739.4 AET40831.1 - 0.4 10.2 6.1 1.3 8.6 0.6 2.6 1 1 1 2 2 2 0 Mini-chromosome maintenance replisome factor PAPA-1 PF04795.7 AET40832.1 - 1.2e-15 57.9 5.3 1.2e-15 57.9 3.7 3.3 2 1 0 3 3 3 1 PAPA-1-like conserved region Utp14 PF04615.8 AET40832.1 - 0.029 12.5 39.4 0.037 12.2 27.3 1.0 1 0 0 1 1 1 0 Utp14 protein RabGAP-TBC PF00566.13 AET40833.1 - 1.1e-33 116.5 11.3 4.8e-30 104.6 4.8 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Rap1-DNA-bind PF09197.5 AET40834.1 - 4e-47 159.0 4.8 1.2e-42 144.6 0.5 2.7 2 0 0 2 2 2 2 Rap1, DNA-binding Rap1_C PF11626.3 AET40834.1 - 4.7e-23 80.8 0.0 7.5e-22 77.0 0.0 2.9 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 AET40834.1 - 2.1e-10 40.5 0.0 3.5e-08 33.3 0.0 3.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 AET40834.1 - 6.2e-08 32.3 0.5 0.0001 22.0 0.0 2.8 2 0 0 2 2 2 2 Rap1 Myb domain BRCT PF00533.21 AET40834.1 - 0.00016 21.7 1.2 0.00035 20.6 0.0 2.2 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_6 PF13921.1 AET40834.1 - 0.0032 17.5 0.6 0.17 11.9 0.0 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain MiaE_2 PF13794.1 AET40834.1 - 0.76 9.2 3.4 2.6 7.5 0.0 2.7 3 0 0 3 3 3 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Metallophos PF00149.23 AET40835.1 - 7.3e-15 54.8 0.2 1e-14 54.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AET40835.1 - 2.3e-05 24.3 0.1 3.8e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Hpt PF01627.18 AET40836.1 - 5e-14 52.0 0.1 6e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Hpt domain MgsA_C PF12002.3 AET40837.1 - 2e-52 177.2 1.9 2.3e-52 177.0 0.3 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 AET40837.1 - 2.6e-15 56.1 0.0 1.1e-14 54.1 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 AET40837.1 - 4e-15 56.1 0.0 8.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AET40837.1 - 5.1e-07 29.4 0.1 2.1e-06 27.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AET40837.1 - 2.1e-06 27.8 0.1 0.00025 21.0 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AET40837.1 - 1.1e-05 25.6 0.5 0.00043 20.4 0.2 3.1 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AET40837.1 - 5.3e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 AET40837.1 - 6.1e-05 22.5 0.1 0.0028 17.1 0.0 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.1 AET40837.1 - 9.1e-05 22.1 0.2 0.0017 18.0 0.0 2.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 AET40837.1 - 0.00015 20.9 0.1 0.051 12.7 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AET40837.1 - 0.0007 19.7 0.0 0.0024 18.0 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 AET40837.1 - 0.0022 17.6 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AET40837.1 - 0.0026 17.6 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 AET40837.1 - 0.0027 18.0 0.0 0.0081 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 AET40837.1 - 0.0035 16.9 0.0 0.0078 15.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AET40837.1 - 0.0067 17.2 0.0 0.024 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 AET40837.1 - 0.0089 15.2 0.2 0.025 13.7 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ResIII PF04851.10 AET40837.1 - 0.0097 15.7 0.3 0.37 10.5 0.1 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 AET40837.1 - 0.011 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 AET40837.1 - 0.015 15.6 0.0 0.048 13.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 AET40837.1 - 0.018 13.9 0.0 0.04 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 AET40837.1 - 0.032 12.9 0.0 0.065 11.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 AET40837.1 - 0.039 13.6 0.3 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 AET40837.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Hydrolase_6 PF13344.1 AET40838.1 - 5.3e-30 103.2 0.0 3.1e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AET40838.1 - 7.7e-13 49.3 0.0 1.2e-11 45.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AET40838.1 - 9.9e-13 47.6 0.0 1.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 AET40838.1 - 1.3e-06 28.7 0.1 0.0046 17.1 0.1 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Glyco_transf_22 PF03901.12 AET40839.1 - 2.3e-91 306.8 28.4 2.9e-91 306.5 19.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Adenylsucc_synt PF00709.16 AET40840.1 - 6.9e-163 542.1 0.0 7.8e-163 542.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MCD PF05292.6 AET40840.1 - 0.028 13.1 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) POP1 PF06978.6 AET40841.1 - 1.3e-68 230.3 13.9 1.3e-68 230.3 9.7 1.8 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 AET40841.1 - 2.3e-30 104.3 0.6 6.3e-30 102.8 0.4 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.6 AET40841.1 - 0.021 14.8 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain GDPD_2 PF13653.1 AET40843.1 - 0.098 12.8 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Ssu72 PF04722.8 AET40844.1 - 2.9e-88 294.3 0.0 3.3e-88 294.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Peptidase_C54 PF03416.14 AET40845.1 - 7.3e-87 291.0 0.0 9.4e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.18 AET40846.1 - 8e-12 44.7 0.5 1.6e-11 43.7 0.3 1.6 1 0 0 1 1 1 1 G-patch domain SID PF11778.3 AET40847.1 - 9.1e-57 190.8 7.8 9.1e-57 190.8 5.4 2.3 2 0 0 2 2 2 1 Septation initiation ATG16 PF08614.6 AET40847.1 - 7.2e-05 22.7 20.6 7.2e-05 22.7 14.3 6.1 2 2 3 5 5 5 1 Autophagy protein 16 (ATG16) Rab5-bind PF09311.6 AET40847.1 - 0.0082 16.0 17.1 0.0082 16.0 11.9 5.0 2 2 3 5 5 5 1 Rabaptin-like protein TMF_DNA_bd PF12329.3 AET40847.1 - 0.012 15.3 13.6 0.012 15.3 9.4 8.9 2 2 6 9 9 9 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 AET40847.1 - 0.018 14.2 46.6 0.063 12.4 3.4 4.7 2 2 4 6 6 6 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 AET40847.1 - 0.29 8.3 80.1 0.4 7.9 9.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) IncA PF04156.9 AET40847.1 - 0.39 10.2 111.7 0.79 9.2 16.8 5.7 2 2 3 5 5 5 0 IncA protein Dala_Dala_lig_N PF01820.16 AET40847.1 - 1.8 8.8 0.0 1.8 8.8 0.0 5.2 3 2 0 3 3 3 0 D-ala D-ala ligase N-terminus AAA_13 PF13166.1 AET40847.1 - 4.2 5.7 90.3 1 7.7 20.2 3.5 2 1 2 4 4 4 0 AAA domain SlyX PF04102.7 AET40847.1 - 9.7 6.6 61.6 0.086 13.2 1.0 7.9 5 2 4 9 9 9 0 SlyX GST_C PF00043.20 AET40848.1 - 9.5e-20 70.3 0.0 1.6e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AET40848.1 - 2e-15 56.7 0.0 4.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AET40848.1 - 1.3e-08 34.7 0.0 6.1e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AET40848.1 - 5.7e-08 32.8 0.0 2.1e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AET40848.1 - 0.0023 17.7 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Elongin_A PF06881.6 AET40850.1 - 4.8e-20 71.9 1.4 4.8e-20 71.9 1.0 3.3 3 1 1 4 4 4 2 RNA polymerase II transcription factor SIII (Elongin) subunit A Rrf2 PF02082.15 AET40850.1 - 0.12 12.4 4.3 8.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Transcriptional regulator Lipase_GDSL_3 PF14606.1 AET40850.1 - 0.18 11.5 1.1 0.41 10.3 0.8 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Hydrolase_3 PF08282.7 AET40850.1 - 1.7 8.1 3.9 0.73 9.3 0.8 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase CRAL_TRIO PF00650.15 AET40851.1 - 7e-41 139.3 0.0 1e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AET40851.1 - 2.6e-10 40.2 0.1 8.8e-10 38.5 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AET40851.1 - 2.6e-05 24.1 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain EXOSC1 PF10447.4 AET40852.1 - 3.2e-32 110.3 0.2 8.9e-32 108.8 0.0 1.8 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 AET40852.1 - 0.0022 18.0 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 2 S1 RNA binding domain Globin PF00042.17 AET40853.1 - 5.6e-07 29.8 0.0 2.5e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Globin Peptidase_S8 PF00082.17 AET40854.1 - 2.4e-53 181.1 2.7 4e-53 180.4 1.9 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 AET40854.1 - 9.7e-26 89.3 0.7 1.9e-25 88.4 0.5 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_C1_2 PF03051.10 AET40855.1 - 6.3e-161 535.7 0.3 7.3e-161 535.5 0.2 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 AET40855.1 - 4.4e-08 33.2 0.1 0.00026 20.9 0.2 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Fe_hyd_lg_C PF02906.9 AET40856.1 - 2.2e-68 230.6 0.0 2.9e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain G6PD_C PF02781.11 AET40857.1 - 9.3e-130 431.7 0.0 1.2e-129 431.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 AET40857.1 - 5.1e-63 212.6 0.0 1.1e-62 211.5 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RhoGAP PF00620.22 AET40858.1 - 2e-33 115.1 0.5 1.1e-32 112.7 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 AET40858.1 - 8.3e-27 93.0 61.0 3.8e-09 36.4 4.1 4.8 5 0 0 5 5 5 4 LIM domain EF-hand_like PF09279.6 AET40858.1 - 0.056 13.4 0.1 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like ATG2_CAD PF13329.1 AET40859.1 - 1.1e-34 119.2 1.8 1.1e-34 119.2 1.2 3.4 4 0 0 4 4 4 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 AET40859.1 - 2.9e-28 97.8 0.3 6.9e-28 96.6 0.2 1.7 1 0 0 1 1 1 1 ATG C terminal domain SNO PF01174.14 AET40860.1 - 2.7e-71 239.0 0.0 3.1e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 AET40860.1 - 8.8e-09 35.1 0.0 4.2e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 AET40860.1 - 2e-05 24.1 0.0 4.9e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 AET40860.1 - 0.00028 20.2 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 AET40860.1 - 0.00037 20.2 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 BPL_N PF09825.4 AET40860.1 - 0.0011 17.8 0.0 0.0046 15.8 0.0 1.8 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal SOR_SNZ PF01680.12 AET40861.1 - 1.6e-101 338.2 3.3 2.1e-101 337.8 2.3 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 AET40861.1 - 4.9e-10 38.9 2.6 9.6e-07 28.1 0.0 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG NanE PF04131.9 AET40861.1 - 0.0022 16.9 2.3 0.34 9.8 0.0 3.3 3 1 0 3 3 3 2 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 AET40861.1 - 0.0023 17.0 0.1 0.017 14.1 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 AET40861.1 - 0.011 14.6 0.3 2.8 6.6 0.0 2.9 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) PEP_mutase PF13714.1 AET40861.1 - 0.024 13.8 0.2 0.14 11.3 0.1 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase His_biosynth PF00977.16 AET40861.1 - 0.065 12.4 0.0 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.10 AET40861.1 - 0.068 12.3 3.6 0.16 11.0 1.4 2.3 1 1 1 2 2 2 0 Nitronate monooxygenase TMP-TENI PF02581.12 AET40861.1 - 0.078 12.0 0.4 0.49 9.4 0.0 2.5 3 1 1 4 4 4 0 Thiamine monophosphate synthase/TENI RRM_1 PF00076.17 AET40862.1 - 0.00045 19.7 0.0 0.03 13.9 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET40862.1 - 0.00058 19.7 0.0 0.0025 17.7 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET40862.1 - 0.027 14.3 0.1 0.38 10.6 0.1 2.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF1 PF04857.15 AET40863.1 - 7.9e-51 172.9 1.3 1.1e-50 172.4 0.9 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NTF2 PF02136.15 AET40864.1 - 1.7e-19 70.2 0.1 3.1e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain MIP-T3 PF10243.4 AET40864.1 - 3.5e-05 22.4 45.9 4.4e-05 22.1 31.8 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RRM_6 PF14259.1 AET40864.1 - 0.0055 16.6 0.2 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mitofilin PF09731.4 AET40864.1 - 1.1 7.8 28.3 1.6 7.3 19.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Y_phosphatase2 PF03162.8 AET40865.1 - 1.1e-32 112.7 2.1 1.1e-30 106.1 1.5 2.3 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF3750 PF12570.3 AET40865.1 - 0.0086 16.3 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3750) Saccharop_dh PF03435.13 AET40866.1 - 2.8e-129 431.4 0.0 3.2e-129 431.2 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 AET40866.1 - 4.9e-09 36.3 0.4 1e-08 35.3 0.3 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 AET40866.1 - 4.6e-05 23.5 0.4 7.4e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AET40866.1 - 5.2e-05 22.0 0.1 7.9e-05 21.4 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 AET40866.1 - 9.8e-05 22.6 0.4 0.0003 21.0 0.2 1.7 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AET40866.1 - 0.00043 20.6 0.3 0.0008 19.7 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 AET40866.1 - 0.0014 18.0 1.0 0.007 15.7 0.2 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain DapB_N PF01113.15 AET40866.1 - 0.0027 17.6 0.3 0.005 16.7 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 AET40866.1 - 0.0056 15.9 0.4 0.0086 15.3 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family GFO_IDH_MocA PF01408.17 AET40866.1 - 0.0085 16.6 0.1 0.017 15.6 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 AET40866.1 - 0.01 16.2 0.5 0.017 15.4 0.4 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 AET40866.1 - 0.07 13.3 0.3 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pterin_bind PF00809.17 AET40866.1 - 0.074 12.4 1.0 2.9 7.2 0.7 2.2 1 1 0 1 1 1 0 Pterin binding enzyme OB_NTP_bind PF07717.11 AET40867.1 - 7.6e-17 61.1 0.1 2.7e-16 59.3 0.0 2.1 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 AET40867.1 - 4e-13 49.2 1.1 1e-11 44.6 0.2 2.8 2 0 0 2 2 2 1 RWD domain DEAD PF00270.24 AET40867.1 - 2.6e-11 43.3 1.7 3.3e-10 39.7 0.1 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase HA2 PF04408.18 AET40867.1 - 2.7e-11 43.3 0.2 1.3e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AET40867.1 - 1.5e-10 40.8 0.1 3.9e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AET40867.1 - 8.9e-05 22.6 0.0 0.00032 20.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AET40867.1 - 0.00071 19.0 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 AET40867.1 - 0.00092 18.1 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 AET40867.1 - 0.0039 16.6 0.0 0.0093 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AET40867.1 - 0.0051 15.9 1.2 0.012 14.7 0.0 2.2 3 0 0 3 3 3 1 KaiC AAA_14 PF13173.1 AET40867.1 - 0.011 15.5 1.2 0.39 10.6 0.2 3.8 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AET40867.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 AET40867.1 - 0.016 14.8 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 AET40867.1 - 0.018 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 AET40867.1 - 0.02 14.1 0.9 0.28 10.4 0.2 3.0 3 1 0 3 3 3 0 PhoH-like protein UBA PF00627.26 AET40867.1 - 0.02 14.7 0.1 0.19 11.5 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain AAA_16 PF13191.1 AET40867.1 - 0.025 14.5 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 AET40867.1 - 0.071 12.5 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain CDC73 PF05179.9 AET40868.1 - 2.3e-64 217.3 1.8 3.4e-64 216.8 1.3 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family PSRP-3_Ycf65 PF04839.8 AET40868.1 - 0.062 13.3 1.9 0.6 10.2 0.0 2.8 2 1 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) EF-hand_1 PF00036.27 AET40869.1 - 1.7e-25 86.3 10.7 1.1e-05 24.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AET40869.1 - 1.8e-20 72.7 2.6 1.2e-10 41.3 1.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AET40869.1 - 1.8e-20 70.8 3.2 0.00026 20.6 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AET40869.1 - 8.5e-17 59.6 16.3 8.2e-05 21.7 0.2 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 AET40869.1 - 1.6e-12 46.8 16.0 0.00096 18.7 0.5 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 AET40869.1 - 5.6e-07 29.2 9.4 0.0049 16.5 0.2 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AET40869.1 - 8e-07 29.0 0.0 0.006 16.5 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 AET40869.1 - 0.0026 17.6 0.1 0.9 9.5 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain Diphthamide_syn PF01866.12 AET40870.1 - 2.5e-41 141.8 0.1 6.3e-40 137.2 0.1 2.3 1 1 0 1 1 1 1 Putative diphthamide synthesis protein GST_N_3 PF13417.1 AET40870.1 - 0.12 12.6 0.0 26 5.1 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Amidohydro_4 PF13147.1 AET40871.1 - 3.8e-08 33.6 0.0 5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 AET40871.1 - 4.9e-06 26.2 0.0 8.4e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Proteasom_Rpn13 PF04683.8 AET40872.1 - 9.4e-22 76.9 0.0 1.8e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ded_cyto PF06920.8 AET40873.1 - 6.3e-22 77.7 0.0 1.3e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis PP-binding PF00550.20 AET40874.1 - 8.3e-13 48.4 0.9 1.1e-12 48.0 0.6 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 AET40874.1 - 4.1e-07 29.9 1.3 6.6e-07 29.2 0.9 1.4 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 AET40874.1 - 0.00015 21.8 0.3 0.00022 21.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) WGG PF10273.4 AET40874.1 - 0.07 13.2 0.2 0.098 12.7 0.2 1.2 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 DUF1073 PF06381.6 AET40874.1 - 0.084 11.3 0.0 0.095 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) Ribosomal_L50 PF10501.4 AET40874.1 - 0.12 12.3 0.0 1.2 9.1 0.0 1.9 1 1 0 2 2 2 0 Ribosomal subunit 39S LRR_4 PF12799.2 AET40875.1 - 3.6e-40 134.9 37.5 4.9e-09 35.6 2.0 7.4 2 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AET40875.1 - 9.3e-32 108.5 49.5 3.7e-09 36.2 0.3 6.3 2 2 6 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 AET40875.1 - 7.8e-18 61.7 27.9 0.054 13.5 0.2 11.5 10 1 0 10 10 10 6 Leucine Rich Repeat LRR_7 PF13504.1 AET40875.1 - 8e-12 43.3 12.2 2.3 8.7 0.0 9.8 10 0 0 10 10 10 3 Leucine rich repeat LRR_6 PF13516.1 AET40875.1 - 2.8e-11 42.2 23.2 0.93 9.7 0.1 10.5 9 2 2 11 11 11 5 Leucine Rich repeat LRR_9 PF14580.1 AET40875.1 - 1.7e-09 37.4 13.8 1.4e-06 27.9 3.0 3.8 1 1 3 4 4 4 4 Leucine-rich repeat Glyco_hydro_4 PF02056.11 AET40875.1 - 0.2 10.9 0.9 0.36 10.1 0.1 1.8 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase DUF3744 PF12558.3 AET40875.1 - 2.9 8.3 14.7 9.3 6.7 1.8 4.5 2 2 3 5 5 5 0 ATP-binding cassette cobalt transporter tRNA-synt_2b PF00587.20 AET40876.1 - 1.1e-47 161.7 0.1 2e-47 160.9 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AET40876.1 - 1.6e-15 56.8 0.1 2.9e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain APG17 PF04108.7 AET40877.1 - 1.5e-98 330.3 25.4 1.7e-98 330.1 17.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4206 PF13901.1 AET40877.1 - 0.027 14.0 8.0 0.36 10.3 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4206) Med30 PF11315.3 AET40877.1 - 0.058 13.5 0.6 0.058 13.5 0.4 3.7 3 1 0 3 3 3 0 Mediator complex subunit 30 Herpes_UL36 PF03586.8 AET40877.1 - 0.075 12.1 1.0 0.44 9.5 0.1 2.3 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein MRP-S26 PF14943.1 AET40877.1 - 0.12 11.8 0.2 0.12 11.8 0.1 3.1 4 0 0 4 4 4 0 Mitochondrial ribosome subunit S26 Endotoxin_N PF03945.9 AET40877.1 - 0.26 10.6 9.2 0.12 11.7 0.3 3.1 2 2 1 3 3 3 0 delta endotoxin, N-terminal domain Lip_prot_lig_C PF10437.4 AET40877.1 - 0.57 9.8 5.4 2.3 7.9 0.0 4.0 3 2 1 4 4 4 0 Bacterial lipoate protein ligase C-terminus IncA PF04156.9 AET40877.1 - 0.94 9.0 22.7 1.6 8.2 4.8 3.3 1 1 2 3 3 3 0 IncA protein Syntaxin-6_N PF09177.6 AET40877.1 - 2.9 8.3 13.1 3.4 8.1 0.2 4.2 3 2 1 4 4 4 0 Syntaxin 6, N-terminal WXG100 PF06013.7 AET40877.1 - 5.3 7.1 6.4 7.6 6.6 0.1 3.8 4 0 0 4 4 4 0 Proteins of 100 residues with WXG G-patch PF01585.18 AET40878.1 - 2e-13 49.8 6.3 3.5e-13 49.1 4.4 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 AET40878.1 - 1.7e-06 27.7 0.8 3.2e-06 26.8 0.5 1.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site GCFC PF07842.7 AET40878.1 - 2e-05 24.0 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Snapin_Pallidin PF14712.1 AET40878.1 - 0.061 13.6 1.4 0.18 12.1 1.0 1.8 1 0 0 1 1 1 0 Snapin/Pallidin CHCH PF06747.8 AET40879.1 - 2.2e-08 33.7 3.7 4.3e-08 32.8 2.5 1.5 1 0 0 1 1 1 1 CHCH domain Pik1 PF11522.3 AET40879.1 - 0.021 14.5 0.3 0.045 13.4 0.2 1.5 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 GCK PF07802.6 AET40879.1 - 0.22 11.6 2.9 0.39 10.8 2.0 1.4 1 0 0 1 1 1 0 GCK domain Synaptobrevin PF00957.16 AET40880.1 - 5.4e-15 54.7 0.8 8.8e-15 54.0 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AET40880.1 - 2.5e-14 52.5 0.0 4.8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain CNH PF00780.17 AET40881.1 - 5.5e-15 55.5 1.6 2e-14 53.6 1.1 1.9 1 1 0 1 1 1 1 CNH domain PH PF00169.24 AET40881.1 - 2.4e-10 40.5 0.7 2.4e-10 40.5 0.5 2.4 2 1 0 2 2 2 1 PH domain RhoGEF PF00621.15 AET40881.1 - 3.8e-09 36.6 0.3 2.4e-08 34.0 0.1 2.3 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 AET40881.1 - 3.5e-05 23.7 2.8 0.00017 21.5 1.9 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain adh_short PF00106.20 AET40882.1 - 2.2e-17 63.4 0.1 6e-17 62.0 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AET40882.1 - 1.7e-05 24.5 0.2 0.00016 21.4 0.1 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 AET40882.1 - 0.011 14.4 0.1 0.025 13.3 0.1 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family SPC25 PF06703.6 AET40883.1 - 2.1e-32 111.9 0.8 2.3e-32 111.8 0.6 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4149 PF13664.1 AET40883.1 - 0.036 14.1 0.1 0.048 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) zf-C3HC4 PF00097.20 AET40884.1 - 2e-07 30.5 2.3 6.7e-07 28.8 1.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET40884.1 - 6.5e-07 29.2 3.1 2.1e-06 27.6 2.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET40884.1 - 9e-07 28.5 3.8 2.2e-06 27.2 2.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 AET40884.1 - 1.3e-06 28.1 3.4 2.6e-06 27.1 2.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AET40884.1 - 8.6e-05 22.1 2.9 0.0002 20.9 2.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AET40884.1 - 0.00018 21.1 1.2 0.00047 19.8 0.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AET40884.1 - 0.00036 20.3 6.0 0.0022 17.8 4.3 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prefoldin PF02996.12 AET40884.1 - 0.022 14.3 1.0 20 4.8 1.3 3.5 3 1 0 3 3 3 0 Prefoldin subunit FYVE PF01363.16 AET40884.1 - 1.1 9.1 6.1 1.3 9.0 2.2 2.4 1 1 1 2 2 2 0 FYVE zinc finger Lar_restr_allev PF14354.1 AET40884.1 - 1.2 9.5 3.7 6.3 7.1 0.3 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF1900 PF08954.6 AET40885.1 - 1.3e-49 167.2 0.0 5e-49 165.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 AET40885.1 - 4.8e-31 106.2 0.2 8.9e-31 105.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 AET40885.1 - 1.2e-25 88.3 6.5 3.4e-08 33.0 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 AET40885.1 - 8.2e-08 30.8 0.3 0.0038 15.4 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 AET40885.1 - 0.0031 17.2 0.2 0.2 11.3 0.0 2.7 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A SEN1_N PF12726.2 AET40886.1 - 2.3e-197 657.4 15.7 3.5e-197 656.8 10.9 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 AET40886.1 - 1.2e-67 227.9 0.7 1.2e-67 227.9 0.5 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 AET40886.1 - 3e-64 216.0 0.8 1.3e-63 214.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AET40886.1 - 1.5e-10 40.6 0.0 4.2e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AET40886.1 - 1.1e-07 31.6 0.0 0.00012 21.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.1 AET40886.1 - 0.0033 17.5 0.1 0.025 14.7 0.0 2.5 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain Reo_sigmaC PF04582.7 AET40887.1 - 6.2 5.8 6.4 5.6 6.0 2.7 2.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein IMPDH PF00478.20 AET40888.1 - 2.6e-143 477.1 3.0 3e-143 476.9 2.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 AET40888.1 - 6.1e-15 54.7 0.0 3.7e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 AET40888.1 - 5.7e-09 35.5 2.1 9.2e-06 25.0 0.8 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 AET40888.1 - 6e-08 31.9 2.2 1.5e-07 30.6 1.5 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 AET40888.1 - 4.5e-05 22.8 1.4 0.00021 20.6 1.0 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 AET40888.1 - 0.0028 16.7 1.7 0.0058 15.7 0.4 1.9 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.14 AET40888.1 - 0.02 14.0 0.7 0.083 12.0 0.1 2.3 2 0 0 2 2 2 0 KDPG and KHG aldolase YL1_C PF08265.6 AET40888.1 - 0.07 12.7 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain EAL PF00563.15 AET40888.1 - 0.17 11.3 0.1 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 EAL domain Metallophos PF00149.23 AET40889.1 - 3.2e-43 147.4 0.1 4.9e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WGG PF10273.4 AET40890.1 - 5.8e-29 100.0 0.3 1.2e-28 98.9 0.2 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 AET40890.1 - 0.029 14.3 0.4 0.05 13.6 0.3 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Glyco_transf_15 PF01793.11 AET40891.1 - 4.6e-116 387.3 13.2 5.8e-116 387.0 9.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase AAA PF00004.24 AET40892.1 - 1.4e-39 135.2 0.0 3.7e-39 133.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AET40892.1 - 1.3e-05 24.3 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AET40892.1 - 1.6e-05 24.9 0.9 0.00039 20.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AET40892.1 - 4.1e-05 23.7 0.1 0.0023 18.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AET40892.1 - 0.00018 21.2 2.0 0.0019 17.9 0.0 3.4 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 AET40892.1 - 0.00018 20.3 3.4 0.0011 17.7 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 AET40892.1 - 0.0026 17.6 0.0 0.0078 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AET40892.1 - 0.0041 16.5 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 AET40892.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AET40892.1 - 0.0046 16.1 0.1 0.01 14.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AET40892.1 - 0.0062 16.2 0.4 0.031 14.0 0.0 2.3 3 0 0 3 3 1 1 Part of AAA domain AAA_11 PF13086.1 AET40892.1 - 0.0067 16.0 0.0 0.0067 16.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AET40892.1 - 0.0078 16.2 2.8 0.11 12.4 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 AET40892.1 - 0.01 16.6 4.5 0.013 16.2 0.0 3.0 3 2 0 3 3 2 0 AAA domain AAA_25 PF13481.1 AET40892.1 - 0.012 15.0 0.2 0.37 10.1 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AET40892.1 - 0.013 15.8 3.0 0.1 12.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain Vps4_C PF09336.5 AET40892.1 - 0.035 13.9 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain AAA_24 PF13479.1 AET40892.1 - 0.088 12.3 0.1 0.3 10.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 AET40892.1 - 0.12 12.0 0.6 2.9 7.5 0.0 2.9 2 1 1 3 3 3 0 NACHT domain GCR1_C PF12550.3 AET40893.1 - 1.3e-24 85.8 1.3 1.3e-24 85.8 0.9 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes WD40 PF00400.27 AET40894.1 - 3.5e-63 207.3 20.0 1.7e-13 49.8 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 AET40894.1 - 8.8e-50 168.4 1.3 1.7e-49 167.5 0.9 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 AET40894.1 - 1.9e-05 24.2 0.0 4.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 AET40894.1 - 4.7e-05 22.3 0.5 0.049 12.3 0.0 3.1 2 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 AET40894.1 - 6.5e-05 21.2 4.1 0.013 13.6 0.1 3.7 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 AET40894.1 - 0.023 13.0 0.1 0.53 8.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Hira PF07569.6 AET40894.1 - 0.061 12.5 0.0 5.3 6.1 0.0 2.9 2 1 1 3 3 3 0 TUP1-like enhancer of split GPI2 PF06432.6 AET40895.1 - 6.8e-60 202.7 30.3 5.7e-59 199.7 21.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase 4HB_MCP_1 PF12729.2 AET40896.1 - 0.011 15.0 0.4 0.012 14.9 0.3 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction PGI PF00342.14 AET40897.1 - 5.8e-219 727.4 1.0 6.6e-219 727.2 0.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase WD40 PF00400.27 AET40898.1 - 2.3e-18 65.3 15.7 8.3e-05 22.3 1.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AET40898.1 - 1.6e-17 63.1 0.5 3.4e-17 62.0 0.3 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex LigD_N PF13298.1 AET40898.1 - 0.027 14.5 0.1 0.17 12.0 0.1 2.3 2 1 0 2 2 2 0 DNA polymerase Ligase (LigD) Mt_ATP-synt_B PF05405.9 AET40899.1 - 3.5e-52 176.1 8.2 4.3e-52 175.8 5.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SRX PF09201.5 AET40899.1 - 0.00011 21.8 1.5 0.00027 20.6 1.1 1.6 2 0 0 2 2 2 1 SRX rve_3 PF13683.1 AET40899.1 - 0.12 11.8 0.2 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Med8 PF10232.4 AET40900.1 - 3.2e-40 138.0 2.2 8e-40 136.7 1.5 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 G10 PF01125.12 AET40900.1 - 0.011 15.2 0.0 0.036 13.6 0.0 1.7 2 0 0 2 2 2 0 G10 protein NPV_P10 PF05531.7 AET40900.1 - 0.044 14.0 0.3 0.38 11.0 0.2 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1741 PF08427.5 AET40900.1 - 0.06 12.8 0.1 0.084 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) DASH_Hsk3 PF08227.6 AET40900.1 - 0.33 11.1 4.5 1.5 9.0 1.5 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Mito_carr PF00153.22 AET40901.1 - 1.1e-78 258.9 0.0 3.6e-27 93.8 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.13 AET40902.1 - 3.3e-44 148.7 5.2 5.3e-44 148.0 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e LRS4 PF10422.4 AET40902.1 - 0.00069 19.0 0.1 0.00082 18.8 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 MarR_2 PF12802.2 AET40902.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 MarR family Ribosomal_S4 PF00163.14 AET40903.1 - 2.2e-27 95.2 1.9 3.3e-27 94.7 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AET40903.1 - 4.6e-14 51.5 0.2 1.6e-13 49.8 0.2 1.9 1 0 0 1 1 1 1 S4 domain DUF3535 PF12054.3 AET40904.1 - 1e-144 482.4 3.1 4.4e-144 480.3 1.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 AET40904.1 - 4.9e-78 261.9 0.0 9.9e-78 260.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 AET40904.1 - 7.5e-16 56.7 3.4 0.42 10.8 0.0 9.0 8 0 0 8 8 8 5 HEAT repeat Helicase_C PF00271.26 AET40904.1 - 1.4e-13 50.5 0.0 3.8e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 AET40904.1 - 2.1e-09 37.5 3.2 1.3 9.3 0.0 7.5 6 3 1 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.2 AET40904.1 - 2.2e-07 31.1 0.2 0.45 10.9 0.0 5.4 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 AET40904.1 - 3e-06 27.5 10.8 2.2 8.8 0.0 8.7 9 1 1 10 10 10 2 HEAT-like repeat cwf18 PF08315.7 AET40905.1 - 4.5e-10 40.0 6.7 9.2e-10 39.0 4.6 1.5 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor Apolipoprotein PF01442.13 AET40905.1 - 0.004 16.6 1.7 0.0072 15.8 1.2 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain UPF0016 PF01169.14 AET40906.1 - 1.2e-40 137.5 22.3 2.1e-22 79.0 4.3 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF308 PF03729.8 AET40906.1 - 0.47 10.4 12.4 3.7 7.6 2.8 2.8 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) 5TM-5TMR_LYT PF07694.7 AET40906.1 - 2.2 7.6 13.6 0.017 14.4 1.6 2.5 2 1 0 2 2 2 0 5TMR of 5TMR-LYT DUF204 PF02659.10 AET40906.1 - 7.5 6.7 12.3 2 8.6 1.9 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF AAA PF00004.24 AET40907.1 - 2.5e-33 115.1 0.0 4.6e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AET40907.1 - 1.2e-08 35.1 0.6 7.5e-08 32.5 0.0 2.6 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 AET40907.1 - 2.1e-07 31.7 0.0 6.8e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AET40907.1 - 7e-07 29.4 1.0 8.2e-06 25.9 0.2 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 AET40907.1 - 3.2e-06 27.4 0.3 2.8e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AET40907.1 - 4.8e-06 26.2 0.1 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 AET40907.1 - 3.1e-05 23.6 0.3 0.00013 21.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AET40907.1 - 8.9e-05 22.3 0.5 0.0004 20.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain DUF1633 PF07794.6 AET40907.1 - 0.00016 19.8 0.0 0.00032 18.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1633) NACHT PF05729.7 AET40907.1 - 0.00044 19.9 0.2 0.0012 18.4 0.2 1.9 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 AET40907.1 - 0.00055 19.8 0.1 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 AET40907.1 - 0.00064 19.6 0.1 0.002 18.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 AET40907.1 - 0.0007 19.0 0.0 0.0021 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AET40907.1 - 0.00079 19.1 0.2 1.6 8.3 0.1 2.7 2 0 0 2 2 2 2 Archaeal ATPase AAA_5 PF07728.9 AET40907.1 - 0.00084 19.0 1.2 0.096 12.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 AET40907.1 - 0.00099 19.2 0.0 0.0041 17.2 0.0 2.1 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 AET40907.1 - 0.0011 19.2 0.4 0.0043 17.3 0.0 2.1 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 AET40907.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 AET40907.1 - 0.0016 18.8 1.3 0.0016 18.8 0.9 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AET40907.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AET40907.1 - 0.0033 16.3 0.0 0.008 15.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 AET40907.1 - 0.0047 15.9 0.0 0.0082 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 AET40907.1 - 0.005 16.5 0.1 0.013 15.1 0.0 1.7 2 0 0 2 2 1 1 NTPase RuvB_N PF05496.7 AET40907.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus FtsK_SpoIIIE PF01580.13 AET40907.1 - 0.015 14.7 0.0 0.043 13.2 0.0 1.7 2 0 0 2 2 1 0 FtsK/SpoIIIE family ResIII PF04851.10 AET40907.1 - 0.017 14.9 0.0 0.19 11.5 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 AET40907.1 - 0.018 14.5 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 AET40907.1 - 0.029 14.4 0.1 0.16 12.0 0.0 2.4 2 1 0 2 2 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 AET40907.1 - 0.035 13.7 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 AET40907.1 - 0.042 13.8 0.1 0.091 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 AET40907.1 - 0.047 12.7 0.1 0.59 9.1 0.0 2.2 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.16 AET40907.1 - 0.048 12.8 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 AET40907.1 - 0.062 12.7 0.2 0.67 9.3 0.0 2.6 2 1 0 2 2 2 0 AAA-like domain Viral_helicase1 PF01443.13 AET40907.1 - 0.067 12.6 0.6 0.18 11.3 0.3 1.9 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 AET40907.1 - 0.073 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 AET40907.1 - 0.077 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MBA1 PF07961.6 AET40908.1 - 3.5e-99 330.4 0.0 4.1e-99 330.1 0.0 1.0 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.16 AET40908.1 - 0.056 11.9 0.0 0.078 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 Sec16_C PF12931.2 AET40909.1 - 3.8e-78 263.0 0.1 6.8e-78 262.2 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 AET40909.1 - 9.3e-17 61.0 0.1 3.6e-16 59.1 0.0 2.2 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Radical_SAM PF04055.16 AET40910.1 - 5.7e-18 65.6 0.1 1.5e-17 64.2 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AET40910.1 - 3e-11 43.1 0.0 9.9e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Beta_elim_lyase PF01212.16 AET40911.1 - 2.1e-52 178.0 0.0 2.6e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AET40911.1 - 0.057 12.1 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Ceramidase PF05875.7 AET40912.1 - 5.4e-96 320.7 20.5 6.2e-96 320.5 14.2 1.0 1 0 0 1 1 1 1 Ceramidase SRF-TF PF00319.13 AET40913.1 - 4e-23 80.4 0.0 8.4e-23 79.3 0.0 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DnaJ-X PF14308.1 AET40913.1 - 0.15 11.3 2.1 0.26 10.5 1.5 1.3 1 0 0 1 1 1 0 X-domain of DnaJ-containing Ribosomal_S6e PF01092.14 AET40914.1 - 4e-64 213.9 1.2 8.3e-64 212.9 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Pyr_redox_2 PF07992.9 AET40915.1 - 9.5e-40 136.6 0.4 1.6e-39 135.8 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AET40915.1 - 2.7e-35 120.7 0.5 1.8e-34 118.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AET40915.1 - 1.8e-17 63.5 2.9 9e-17 61.2 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AET40915.1 - 4.6e-12 46.4 0.0 2.7e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AET40915.1 - 3.8e-06 26.2 0.0 7.3e-06 25.3 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 AET40915.1 - 1e-05 24.6 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 AET40915.1 - 0.0002 19.9 1.6 0.18 10.2 0.3 3.1 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 AET40915.1 - 0.00024 20.1 3.1 0.00078 18.4 0.3 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 AET40915.1 - 0.0023 17.0 0.2 0.39 9.8 0.0 3.0 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 AET40915.1 - 0.0053 16.3 0.1 0.14 11.6 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 AET40915.1 - 0.0077 15.1 2.8 0.0082 15.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 AET40915.1 - 0.011 15.4 0.9 0.03 14.0 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 AET40915.1 - 0.023 13.7 2.3 0.96 8.4 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 AET40915.1 - 0.028 13.4 0.7 0.068 12.2 0.1 1.9 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 AET40915.1 - 0.049 13.0 0.1 0.09 12.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 AET40915.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 AET40915.1 - 0.25 10.1 3.6 0.21 10.4 1.1 1.9 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.11 AET40916.1 - 1e-43 149.4 24.0 1.5e-43 148.9 16.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AET40916.1 - 3.9e-16 58.6 25.0 4.5e-14 51.8 1.5 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter NOGCT PF08155.6 AET40917.1 - 1.1e-26 92.3 1.6 2.5e-26 91.1 1.1 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 AET40917.1 - 3e-26 91.0 0.4 3.8e-25 87.5 0.3 2.5 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 AET40917.1 - 1.2e-15 57.4 0.0 2.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AET40917.1 - 3.8e-08 32.7 0.0 8.4e-08 31.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 AET40917.1 - 0.00014 21.1 0.3 0.00023 20.3 0.2 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AET40917.1 - 0.00093 19.6 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 AET40917.1 - 0.035 13.9 0.0 10 5.9 0.0 2.8 1 1 1 2 2 2 0 Dynamin family MobB PF03205.9 AET40917.1 - 0.038 13.6 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 AET40917.1 - 1.5 9.0 8.1 7.9 6.7 1.6 3.1 1 1 1 2 2 2 0 AAA domain Sec62 PF03839.11 AET40918.1 - 2e-57 194.2 0.2 2.3e-57 194.0 0.1 1.0 1 0 0 1 1 1 1 Translocation protein Sec62 Ost4 PF10215.4 AET40918.1 - 4.9 6.7 12.2 6.3 6.3 0.9 2.4 2 0 0 2 2 2 0 Oligosaccaryltransferase Dynamin_N PF00350.18 AET40919.1 - 4.4e-17 62.4 0.2 4.4e-17 62.4 0.1 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 AET40919.1 - 4e-10 39.6 0.1 2.6e-09 37.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AET40919.1 - 6.9e-10 38.6 0.6 4.4e-09 36.0 0.6 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 AET40919.1 - 0.0014 18.1 0.2 0.17 11.2 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 AET40919.1 - 0.0022 17.5 0.3 2.4 7.6 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 AET40919.1 - 0.0042 17.3 0.4 0.08 13.2 0.0 2.9 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AET40919.1 - 0.018 14.5 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 AET40919.1 - 0.021 15.3 1.3 0.39 11.2 0.0 3.0 2 1 1 3 3 3 0 Miro-like protein FeoB_N PF02421.13 AET40919.1 - 0.52 9.5 4.3 9 5.5 0.0 3.1 4 0 0 4 4 4 0 Ferrous iron transport protein B Abhydrolase_1 PF00561.15 AET40920.1 - 4.9e-21 75.3 0.0 2.1e-20 73.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AET40920.1 - 4.2e-12 46.4 0.0 7.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AET40920.1 - 1.6e-07 31.1 0.0 1e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 AET40920.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Cutinase PF01083.17 AET40920.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase Rad4 PF03835.10 AET40921.1 - 2e-14 53.1 1.5 2e-14 53.1 1.0 1.6 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 AET40921.1 - 2e-10 40.8 0.1 4e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily zf-TFIIB PF13453.1 AET40921.1 - 4.2 6.6 7.7 0.85 8.8 1.8 2.4 3 0 0 3 3 3 0 Transcription factor zinc-finger tRNA-synt_1b PF00579.20 AET40922.1 - 5.7e-72 242.3 0.0 7.8e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Romo1 PF10247.4 AET40923.1 - 2.1e-28 98.3 7.0 2.7e-28 97.9 4.8 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 MIF4G_like_2 PF09090.6 AET40924.1 - 0.014 14.6 0.4 0.017 14.3 0.3 1.1 1 0 0 1 1 1 0 MIF4G like OPA3 PF07047.7 AET40924.1 - 0.037 13.8 0.9 0.11 12.3 0.6 1.7 1 1 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Poty_PP PF08440.5 AET40924.1 - 0.066 12.2 0.8 0.1 11.6 0.6 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein Nucleoporin_N PF08801.6 AET40925.1 - 6.6e-07 28.4 0.2 0.016 13.9 0.0 3.2 1 1 2 3 3 3 3 Nup133 N terminal like WD40 PF00400.27 AET40925.1 - 1e-06 28.3 1.5 0.00093 18.9 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_N PF14781.1 AET40925.1 - 0.41 10.2 3.0 1.6 8.3 0.0 2.6 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal PAXNEB PF05625.6 AET40926.1 - 2.6e-106 355.5 0.4 3.1e-106 355.2 0.3 1.0 1 0 0 1 1 1 1 PAXNEB protein Lactamase_B_2 PF12706.2 AET40927.1 - 1.8e-31 109.1 0.1 2.6e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AET40927.1 - 8.6e-13 48.3 0.1 1.7e-12 47.3 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AET40927.1 - 0.008 15.8 0.3 0.067 12.8 0.2 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Pantoate_transf PF02548.10 AET40928.1 - 6.5e-95 317.1 0.1 7.7e-95 316.9 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 AET40928.1 - 0.00013 21.2 0.1 0.00033 19.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Abhydrolase_6 PF12697.2 AET40929.1 - 1.4e-23 84.0 0.0 1.8e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET40929.1 - 1.3e-12 47.8 0.0 2.4e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AET40929.1 - 2.9e-10 40.0 0.0 4.5e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 AET40929.1 - 5.7e-05 23.4 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF2048 PF09752.4 AET40929.1 - 0.00028 19.8 0.0 0.00033 19.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_3 PF07859.8 AET40929.1 - 0.00028 20.5 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 AET40929.1 - 0.00087 18.7 0.0 0.0023 17.4 0.0 1.7 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 AET40929.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 AET40929.1 - 0.007 15.6 0.0 0.034 13.4 0.0 2.1 2 1 0 2 2 2 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 AET40929.1 - 0.013 13.8 0.1 3.5 5.8 0.0 3.0 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II DUF915 PF06028.6 AET40929.1 - 0.018 14.1 1.4 0.059 12.4 0.1 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 AET40929.1 - 0.022 14.1 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_2 PF02230.11 AET40929.1 - 0.038 13.4 0.0 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ndr PF03096.9 AET40929.1 - 0.1 11.0 0.0 0.19 10.1 0.0 1.4 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 AET40929.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF676 PF05057.9 AET40929.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 AET40929.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) tRNA-synt_2 PF00152.15 AET40930.1 - 4.1e-110 367.6 0.0 5.8e-110 367.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AET40930.1 - 1.9e-05 24.3 0.2 3.7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 AET40930.1 - 0.0035 16.9 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.27 AET40931.1 - 2.4e-29 100.1 19.2 3.5e-08 33.0 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 AET40931.1 - 0.0011 17.8 0.0 0.072 11.8 0.0 2.3 2 1 0 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 AET40931.1 - 0.0063 16.2 0.0 0.41 10.3 0.0 2.9 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 AET40931.1 - 0.0086 16.3 0.0 0.18 12.1 0.0 2.7 2 0 0 2 2 2 1 PQQ-like domain UMP1 PF05348.6 AET40932.1 - 3.8e-35 120.6 0.0 4.7e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 IIGP PF05049.8 AET40932.1 - 0.023 13.5 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GYF PF02213.11 AET40933.1 - 4.3e-16 58.2 1.6 1e-15 57.0 1.1 1.7 1 0 0 1 1 1 1 GYF domain Sec66 PF09802.4 AET40934.1 - 1e-78 263.1 1.8 1.1e-78 262.9 1.3 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Oxidored_q5_N PF01059.12 AET40934.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus DUF1616 PF07760.6 AET40934.1 - 0.037 13.1 0.1 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Adeno_E3_CR2 PF02439.10 AET40934.1 - 0.039 13.5 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 NPL4 PF05021.10 AET40935.1 - 3.3e-119 397.6 0.0 4.5e-119 397.1 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 AET40935.1 - 1.2e-70 235.8 1.1 1.2e-70 235.8 0.8 1.7 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 AET40935.1 - 0.0007 19.8 0.3 0.0024 18.1 0.0 2.1 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 Sulfate_transp PF00916.15 AET40936.1 - 1.6e-46 158.6 1.4 1.6e-46 158.6 1.0 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AET40936.1 - 9.6e-27 92.4 1.4 9.6e-27 92.4 1.0 2.1 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AET40936.1 - 1.6e-17 62.9 0.0 2.8e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain HopW1-1 PF15457.1 AET40936.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Oxidored-like PF09791.4 AET40937.1 - 1.5e-23 81.9 0.4 3e-23 80.9 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Pex24p PF06398.6 AET40938.1 - 1.5e-37 129.2 10.3 1.9e-37 128.9 7.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpp20 PF12328.3 AET40939.1 - 1.5e-28 99.2 4.7 2.3e-27 95.3 3.3 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 AET40939.1 - 1.4e-16 59.7 0.6 1.4e-16 59.7 0.4 1.5 2 0 0 2 2 2 1 Alba BAAT_C PF08840.6 AET40939.1 - 0.045 13.4 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Phage_Mu_Gam PF07352.7 AET40939.1 - 0.61 9.5 5.0 0.19 11.2 0.7 2.0 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF2119 PF09892.4 AET40940.1 - 0.061 12.5 0.8 0.087 12.0 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Ureidogly_hydro PF04115.7 AET40941.1 - 2.1e-44 150.7 0.0 2.4e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase PDH PF02153.12 AET40942.1 - 2.6e-10 39.6 0.0 4.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 AET40942.1 - 4.4e-05 23.8 0.0 9.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 AET40942.1 - 6e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 AET40942.1 - 0.00067 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 AET40942.1 - 0.00073 18.7 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AET40942.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AET40942.1 - 0.0054 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 AET40942.1 - 0.07 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF123 PF01986.11 AET40943.1 - 0.062 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF123 Arf PF00025.16 AET40944.1 - 1.3e-76 255.7 0.1 1.4e-76 255.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AET40944.1 - 1.9e-11 43.6 0.0 2.2e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 AET40944.1 - 3.5e-11 42.6 0.0 4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AET40944.1 - 1.2e-10 40.9 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 AET40944.1 - 1.5e-09 37.0 0.4 3.3e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AET40944.1 - 2.6e-09 37.5 0.0 3.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 AET40944.1 - 3.5e-05 23.3 0.3 0.0005 19.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AET40944.1 - 0.00015 21.6 0.1 0.00023 21.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AET40944.1 - 0.00036 20.8 0.5 0.0015 18.8 0.3 1.8 1 1 0 1 1 1 1 ABC transporter ArgK PF03308.11 AET40944.1 - 0.0022 16.8 1.5 0.19 10.4 0.4 2.9 2 1 0 2 2 2 1 ArgK protein cobW PF02492.14 AET40944.1 - 0.1 12.0 1.0 4.4 6.6 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 AET40944.1 - 0.11 11.8 0.4 0.54 9.6 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC1 PF03109.11 AET40945.1 - 1.1e-20 73.7 0.0 2.4e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family GDPD PF03009.12 AET40946.1 - 3.7e-75 252.7 0.0 1.3e-74 250.9 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 AET40946.1 - 6.6e-36 122.5 0.1 7.6e-14 51.8 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) SPX PF03105.14 AET40946.1 - 6.7e-33 114.6 18.0 1.9e-23 83.6 2.0 3.1 4 0 0 4 4 4 2 SPX domain Ank PF00023.25 AET40946.1 - 4.4e-24 83.0 1.4 6.6e-05 22.5 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 AET40946.1 - 2.5e-19 69.2 0.7 3.4e-06 27.4 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET40946.1 - 1.6e-18 64.9 1.5 0.024 14.8 0.0 7.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 AET40946.1 - 2.7e-16 59.2 0.0 0.0027 17.9 0.0 6.0 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Arginase PF00491.16 AET40948.1 - 5.6e-73 245.6 0.0 6.5e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family SKG6 PF08693.5 AET40949.1 - 3.1e-08 32.8 0.5 4.1e-08 32.4 0.3 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.1 AET40949.1 - 0.00044 19.7 0.0 0.00048 19.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TMEM154 PF15102.1 AET40949.1 - 0.0085 15.8 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family 7tm_1 PF00001.16 AET40949.1 - 0.038 13.1 0.0 0.038 13.1 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) CcoS PF03597.10 AET40949.1 - 0.056 12.9 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF4448 PF14610.1 AET40949.1 - 0.083 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PEX11 PF05648.9 AET40950.1 - 1e-06 28.1 6.0 0.0013 18.0 1.2 2.8 3 1 0 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) 2-Hacid_dh_C PF02826.14 AET40951.1 - 1.9e-35 121.6 0.0 4.2e-35 120.5 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIA PF03153.8 AET40952.1 - 1.9e-57 195.8 17.7 6.7e-32 111.8 9.9 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit ChlamPMP_M PF07548.6 AET40952.1 - 0.073 12.8 0.5 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Kinetocho_Slk19 PF12709.2 AET40953.1 - 1.7e-30 104.9 16.5 1.7e-30 104.9 11.5 9.0 4 2 4 9 9 9 1 Central kinetochore-associated WEMBL PF05701.6 AET40953.1 - 0.00043 18.8 56.7 0.00043 18.8 39.3 3.1 1 1 2 3 3 2 1 Weak chloroplast movement under blue light AAA_13 PF13166.1 AET40953.1 - 0.0022 16.5 21.9 0.0022 16.5 15.2 4.1 1 1 3 4 4 3 2 AAA domain TPR_MLP1_2 PF07926.7 AET40953.1 - 0.0037 17.0 42.8 0.0069 16.1 9.6 6.4 1 1 5 6 6 5 3 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 AET40953.1 - 0.0038 16.4 1.4 0.0038 16.4 1.0 5.0 1 1 4 5 5 5 3 Reovirus sigma C capsid protein CBM49 PF09478.5 AET40953.1 - 0.011 15.8 0.6 0.052 13.6 0.0 2.5 3 0 0 3 3 2 0 Carbohydrate binding domain CBM49 Prefoldin PF02996.12 AET40953.1 - 0.016 14.8 3.1 0.016 14.8 2.2 9.5 4 4 2 9 9 9 0 Prefoldin subunit SlyX PF04102.7 AET40953.1 - 0.018 15.4 7.1 0.018 15.4 4.9 9.4 7 2 2 9 9 9 0 SlyX NPBW PF15180.1 AET40953.1 - 0.21 11.2 1.5 2.8 7.5 0.0 2.9 2 0 0 2 2 2 0 Neuropeptides B and W IncA PF04156.9 AET40953.1 - 0.93 9.0 114.1 0.041 13.4 17.9 5.9 1 1 3 5 5 5 0 IncA protein DUF869 PF05911.6 AET40953.1 - 1.2 7.2 98.4 0.03 12.5 28.7 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) RhoGAP PF00620.22 AET40954.1 - 3.1e-33 114.5 0.0 6.5e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 AET40954.1 - 9e-06 25.8 0.1 2.2e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.19 AET40954.1 - 2e-05 24.3 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 PX domain DUF1708 PF08101.6 AET40954.1 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Radical_SAM PF04055.16 AET40955.1 - 8.6e-13 48.7 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.6 AET40955.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal NIF PF03031.13 AET40956.1 - 1.4e-50 171.0 0.2 2.5e-50 170.2 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Formyl_trans_N PF00551.14 AET40956.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Formyl transferase WD40 PF00400.27 AET40957.1 - 7.8e-35 117.5 1.8 2.5e-08 33.4 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 AET40957.1 - 7.7e-29 99.5 14.5 7.7e-29 99.5 10.0 1.8 2 0 0 2 2 2 1 Sof1-like domain BBS2_Mid PF14783.1 AET40957.1 - 0.00062 19.5 0.8 1.1 9.0 0.0 3.9 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Peptidase_S76 PF13611.1 AET40957.1 - 9.4 6.3 8.7 21 5.2 2.8 2.5 1 1 1 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 Abhydro_lipase PF04083.11 AET40958.1 - 2.9e-15 55.3 0.0 5.5e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 AET40958.1 - 8.9e-07 29.0 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET40958.1 - 0.00057 19.5 0.0 0.0018 17.8 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 AET40958.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) chaperone_DMP PF10448.4 AET40959.1 - 5.4e-30 104.1 0.0 6.2e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 20S proteasome chaperone SBDS_C PF09377.5 AET40960.1 - 2.9e-35 120.6 0.9 6.3e-35 119.5 0.6 1.6 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 AET40960.1 - 1.7e-31 107.8 0.3 3e-31 107.0 0.2 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HlyIII PF03006.15 AET40961.1 - 2.1e-53 181.0 15.9 2.1e-53 181.0 11.0 1.4 2 0 0 2 2 2 1 Haemolysin-III related PUF PF00806.14 AET40962.1 - 1.3e-53 175.5 13.2 6.5e-08 31.6 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SprA-related PF12118.3 AET40962.1 - 9.1e-05 21.9 41.0 9.1e-05 21.9 28.4 1.9 2 0 0 2 2 2 1 SprA-related family Med15 PF09606.5 AET40962.1 - 0.00051 18.3 72.2 0.00051 18.3 50.1 1.7 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal FLO_LFY PF01698.11 AET40962.1 - 2.7 6.7 22.9 4.8 5.9 15.9 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 AET40962.1 - 3.1 7.5 20.3 9.8 5.8 14.1 2.0 1 0 0 1 1 1 0 Protein Family FAM60A LMBR1 PF04791.11 AET40962.1 - 7.6 4.9 8.4 14 4.0 5.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Rab5ip PF07019.7 AET40963.1 - 1.1e-18 67.1 3.6 1.3e-18 66.8 2.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.9 AET40964.1 - 2.3e-72 242.5 0.1 6.4e-71 237.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 AET40964.1 - 2.2e-24 84.7 1.0 5.8e-24 83.4 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Adaptin_N PF01602.15 AET40964.1 - 0.0021 16.4 0.7 0.0036 15.6 0.5 1.4 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AET40964.1 - 0.065 13.5 0.0 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats TFIIF_alpha PF05793.7 AET40965.1 - 2.6e-09 35.9 0.4 2.6e-09 35.9 0.3 3.5 3 1 1 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vac7 PF12751.2 AET40965.1 - 0.0039 16.0 0.7 0.008 15.0 0.5 1.5 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 tRNA-synt_1b PF00579.20 AET40966.1 - 6.7e-73 245.3 0.0 8.3e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.15 AET40967.1 - 4.4e-14 51.9 8.7 1.8e-13 49.9 6.0 2.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 AET40967.1 - 0.033 14.0 3.5 0.19 11.5 2.5 2.4 1 0 0 1 1 1 0 Ring finger domain Cut8_M PF14483.1 AET40967.1 - 0.043 13.6 3.6 9.2 6.1 0.0 4.8 6 0 0 6 6 6 0 Cut8 dimerisation domain UCR_UQCRX_QCR9 PF05365.7 AET40968.1 - 2.6e-27 94.1 2.6 2.9e-27 94.0 1.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2976 PF11190.3 AET40968.1 - 0.052 13.0 0.2 0.059 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) zf-Tim10_DDP PF02953.10 AET40969.1 - 3.8e-18 64.5 0.6 6e-18 63.8 0.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Myb_DNA-bind_6 PF13921.1 AET40969.1 - 0.033 14.2 0.3 3.8 7.6 0.0 2.2 1 1 0 2 2 2 0 Myb-like DNA-binding domain Glyco_hydro_65m PF03632.10 AET40970.1 - 3.5e-97 325.3 1.7 1.9e-96 322.9 1.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 AET40970.1 - 4.5e-25 88.4 1.6 9.2e-18 64.4 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 AET40970.1 - 6.9e-06 26.0 0.0 2.4e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain DUF2457 PF10446.4 AET40970.1 - 1.7 7.2 19.5 2.8 6.5 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATP-synt_ab PF00006.20 AET40971.1 - 7.5e-70 234.7 0.0 1.1e-69 234.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AET40971.1 - 5.5e-28 97.6 0.6 1.5e-27 96.2 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AET40971.1 - 5.6e-18 64.9 2.0 1.6e-17 63.4 1.4 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AET40971.1 - 0.0064 16.3 1.0 0.015 15.1 0.7 1.7 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 AET40971.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Tex_N PF09371.5 AET40971.1 - 0.014 14.6 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Cyclin_N PF00134.18 AET40972.1 - 1.1e-10 41.1 0.7 3.4e-10 39.5 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF2320 PF10082.4 AET40972.1 - 0.0016 17.2 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2320) TFIIB PF00382.14 AET40972.1 - 0.0025 17.5 0.0 0.0081 15.9 0.0 1.9 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Peptidase_M41 PF01434.13 AET40973.1 - 1.6e-71 240.1 0.2 2.7e-71 239.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AET40973.1 - 7.7e-41 139.3 0.0 3.4e-40 137.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AET40973.1 - 2.6e-05 24.3 0.1 0.015 15.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AET40973.1 - 0.0001 22.3 0.6 0.00091 19.2 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AET40973.1 - 0.00046 20.9 0.1 0.0018 19.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 AET40973.1 - 0.00047 18.9 0.0 0.001 17.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 AET40973.1 - 0.00059 19.2 0.8 0.049 13.0 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 AET40973.1 - 0.0014 18.3 1.5 0.0043 16.7 1.1 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 AET40973.1 - 0.0016 17.5 0.0 0.0047 16.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AET40973.1 - 0.003 17.3 0.1 0.011 15.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AET40973.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 AET40973.1 - 0.017 15.4 0.0 0.05 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AET40973.1 - 0.023 13.8 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 AET40973.1 - 0.037 13.9 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AET40973.1 - 0.041 13.0 0.2 0.097 11.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 AET40973.1 - 0.046 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AET40973.1 - 0.12 11.6 0.2 0.26 10.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 AET40973.1 - 0.3 11.0 2.0 0.32 10.9 0.0 2.1 3 0 0 3 3 2 0 AAA domain Cnd2 PF05786.9 AET40974.1 - 8.8e-130 434.4 43.5 2e-129 433.2 30.1 1.5 1 1 0 1 1 1 1 Condensin complex subunit 2 ScpA_ScpB PF02616.9 AET40974.1 - 0.25 10.9 5.7 0.76 9.3 0.0 3.3 3 1 0 3 3 3 0 ScpA/B protein FAD_binding_3 PF01494.14 AET40975.1 - 1e-16 60.9 0.0 6.8e-16 58.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 AET40975.1 - 1.5e-05 24.0 0.1 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 AET40975.1 - 3.3e-05 24.2 0.0 9.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AET40975.1 - 4.4e-05 22.5 0.0 6.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 AET40975.1 - 4.8e-05 23.3 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AET40975.1 - 6.8e-05 21.9 0.0 0.0003 19.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 AET40975.1 - 0.0053 16.4 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 AET40975.1 - 0.0097 14.5 0.1 0.46 9.0 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.19 AET40975.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 AET40975.1 - 0.012 14.1 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 AET40975.1 - 0.014 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 AET40975.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 AET40975.1 - 0.022 14.6 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 AET40975.1 - 0.046 13.4 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TMEM237 PF15383.1 AET40975.1 - 0.066 12.3 0.1 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 4HBT PF03061.17 AET40976.1 - 1.5e-06 28.2 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily ArfGap PF01412.13 AET40977.1 - 4.1e-34 116.8 0.5 8.9e-34 115.7 0.3 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Rox3 PF08633.5 AET40978.1 - 6e-62 209.3 0.5 6.9e-62 209.1 0.3 1.0 1 0 0 1 1 1 1 Rox3 mediator complex subunit RecQ5 PF06959.6 AET40978.1 - 0.064 12.8 1.0 0.11 12.1 0.7 1.3 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) Ribosomal_L32e PF01655.13 AET40979.1 - 1.1e-45 154.1 2.4 1.3e-45 153.9 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF3437 PF11919.3 AET40979.1 - 0.094 12.4 0.3 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Motile_Sperm PF00635.21 AET40980.1 - 3.2e-25 87.8 0.1 6.8e-25 86.8 0.0 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Peptidase_M24 PF00557.19 AET40981.1 - 8.5e-51 172.4 0.0 1.1e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S21 PF01165.15 AET40982.1 - 1.1e-10 40.8 0.7 1.9e-10 40.0 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Aa_trans PF01490.13 AET40983.1 - 1.1e-101 340.3 28.1 1.2e-101 340.1 19.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SH3_1 PF00018.23 AET40984.1 - 2.4e-11 42.8 0.1 4e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AET40984.1 - 2.9e-11 42.7 0.1 5.1e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AET40984.1 - 5.3e-09 35.4 0.0 9.7e-09 34.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L14 PF00238.14 AET40985.1 - 4.6e-31 107.0 0.0 5.2e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-C3HC4 PF00097.20 AET40986.1 - 1.5e-10 40.5 5.2 2.3e-10 39.9 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AET40986.1 - 5.3e-10 38.8 5.1 7.6e-10 38.3 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AET40986.1 - 2.5e-08 33.6 6.9 3.8e-08 33.0 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AET40986.1 - 1.6e-07 31.2 6.8 2.5e-07 30.5 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET40986.1 - 3.6e-07 29.7 6.0 5.6e-07 29.1 4.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AET40986.1 - 2.1e-05 24.1 3.6 4.1e-05 23.1 2.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AET40986.1 - 0.0011 18.8 7.6 0.0018 18.0 5.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 AET40986.1 - 0.082 12.7 2.3 0.13 12.0 1.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AET40986.1 - 0.11 12.6 2.5 0.26 11.4 1.8 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 AET40986.1 - 0.45 10.1 7.6 5.9 6.5 5.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Cwf_Cwc_15 PF04889.7 AET40986.1 - 2.4 7.8 7.8 4.1 7.0 5.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NT-C2 PF10358.4 AET40988.1 - 9.3e-40 135.4 1.1 4.4e-39 133.2 0.6 2.0 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2233 PF09992.4 AET40989.1 - 0.0029 17.6 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2233) DUF2629 PF10945.3 AET40989.1 - 0.031 13.6 0.1 0.077 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2629) SelP_N PF04592.9 AET40989.1 - 0.075 12.4 1.3 0.097 12.0 0.1 1.7 1 1 1 2 2 2 0 Selenoprotein P, N terminal region PH PF00169.24 AET40990.1 - 3.5e-13 49.6 0.0 7.7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 AET40990.1 - 2.6e-12 46.4 0.0 4.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 AET40990.1 - 7.2e-12 44.5 0.3 1.8e-11 43.2 0.2 1.7 1 0 0 1 1 1 1 SH3 domain PH_11 PF15413.1 AET40990.1 - 3.8e-09 36.7 0.0 1.5e-08 34.8 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_9 PF14604.1 AET40990.1 - 2.1e-08 33.6 0.1 3.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 AET40990.1 - 2.3e-05 24.4 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 AET40990.1 - 7.1e-05 22.8 0.0 0.0023 17.9 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.12 AET40990.1 - 0.0013 18.2 0.0 0.0029 17.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_PNT PF02198.11 AET40990.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain NEP PF10167.4 AET40990.1 - 1.4 8.5 6.5 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised conserved protein TPR_2 PF07719.12 AET40991.1 - 1.7e-42 139.9 12.0 1.8e-07 30.5 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 AET40991.1 - 2.6e-42 142.3 22.6 4.5e-14 51.8 2.7 7.9 4 2 4 8 8 8 5 TPR repeat Apc3 PF12895.2 AET40991.1 - 5.4e-38 129.0 24.0 3.8e-22 78.2 2.0 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 AET40991.1 - 5.6e-35 117.5 21.8 3.6e-08 32.6 0.0 9.1 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 AET40991.1 - 7.4e-28 94.2 12.3 5.7e-05 22.6 0.3 8.6 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 AET40991.1 - 1.2e-23 83.1 3.6 2.4e-07 31.2 0.0 6.7 5 3 2 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 AET40991.1 - 1.9e-22 79.0 21.0 2e-06 27.6 0.8 7.8 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 AET40991.1 - 2.1e-22 77.3 18.3 3.1e-05 23.8 0.2 8.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 AET40991.1 - 5.3e-18 63.8 4.4 0.067 13.8 0.0 7.9 5 2 3 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 AET40991.1 - 1.1e-14 52.9 5.2 0.25 11.2 0.0 8.1 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 AET40991.1 - 1.8e-13 50.6 5.8 5.1e-05 23.5 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AET40991.1 - 9.9e-13 47.6 18.7 0.043 14.2 0.0 10.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_15 PF13429.1 AET40991.1 - 2e-10 40.2 0.9 0.01 14.8 0.0 4.7 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 AET40991.1 - 5.6e-05 22.9 3.7 1.4 8.9 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 AET40991.1 - 0.00014 21.6 0.9 0.28 11.0 0.1 4.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 AET40991.1 - 0.0021 18.3 0.3 3.9 8.1 0.0 4.7 6 0 0 6 6 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 AET40991.1 - 0.0021 17.8 1.2 1.2 8.8 0.1 4.6 3 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 AET40991.1 - 0.0062 16.3 13.1 1.1 9.1 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat BTAD PF03704.12 AET40991.1 - 0.0069 16.7 0.0 0.29 11.4 0.0 2.9 2 1 1 3 3 3 1 Bacterial transcriptional activator domain IRF-3 PF10401.4 AET40991.1 - 0.064 12.8 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Interferon-regulatory factor 3 TPR_20 PF14561.1 AET40991.1 - 0.071 13.2 0.1 38 4.4 0.0 3.7 4 1 1 5 5 3 0 Tetratricopeptide repeat PPR PF01535.15 AET40991.1 - 3.1 7.9 7.5 39 4.5 0.0 4.5 5 0 0 5 5 4 0 PPR repeat MIT PF04212.13 AET40991.1 - 7.1 6.5 8.1 23 4.9 0.0 4.9 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain EMP70 PF02990.11 AET40992.1 - 4.4e-76 256.4 31.9 2.7e-44 151.5 0.4 2.8 2 1 0 2 2 2 2 Endomembrane protein 70 LSM PF01423.17 AET40993.1 - 1.6e-14 53.2 0.9 2.6e-14 52.4 0.6 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AET40993.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain UPF0228 PF05727.6 AET40993.1 - 0.09 12.5 0.1 1.2 8.8 0.0 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0228) Ank_2 PF12796.2 AET40994.1 - 6.2e-08 32.8 1.4 0.0034 17.6 0.0 3.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AET40994.1 - 3.3e-07 29.7 2.0 0.0042 16.8 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 AET40994.1 - 4.3e-07 30.2 5.3 0.0037 17.7 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 AET40994.1 - 4.5e-07 29.4 0.3 3.7e-06 26.5 0.2 2.6 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.1 AET40994.1 - 1.3e-05 25.2 2.3 0.036 14.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AET40994.1 - 6.8e-05 22.7 3.3 0.16 12.3 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat HEAT_EZ PF13513.1 AET40995.1 - 1.7e-16 60.1 0.1 0.074 13.5 0.0 8.9 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.1 AET40995.1 - 1.7e-14 53.8 5.4 0.002 18.3 0.0 6.9 6 2 0 6 6 6 4 HEAT repeats HEAT PF02985.17 AET40995.1 - 6.7e-14 50.6 0.4 0.1 12.7 0.0 8.2 7 0 0 7 7 7 3 HEAT repeat IBN_N PF03810.14 AET40995.1 - 6.5e-12 45.2 3.5 8e-10 38.5 0.1 4.2 3 1 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 AET40995.1 - 6.5e-08 32.8 4.9 7.8 6.9 0.0 6.9 5 2 2 7 7 7 2 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 AET40995.1 - 1.3e-06 28.3 0.3 0.34 10.9 0.0 5.9 5 1 1 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.3 AET40995.1 - 1.6e-06 27.6 3.0 0.47 9.7 0.0 5.3 5 0 0 5 5 5 2 CLASP N terminal RIX1 PF08167.7 AET40995.1 - 1.2e-05 25.0 0.6 0.2 11.3 0.1 4.9 3 2 0 4 4 4 1 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 AET40995.1 - 0.2 12.1 1.2 84 4.0 0.0 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat ALG3 PF05208.8 AET40996.1 - 1.9e-117 392.5 32.2 2.5e-117 392.2 22.4 1.1 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.6 AET40997.1 - 5.4e-08 32.3 0.4 8.6e-08 31.6 0.3 1.3 1 0 0 1 1 1 1 LisH WD40 PF00400.27 AET40998.1 - 2.7e-29 99.9 7.7 7.8e-07 28.7 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 AET40998.1 - 7.2e-05 21.1 0.6 0.0037 15.4 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 CPSF73-100_C PF11718.3 AET40999.1 - 0.095 12.0 2.0 0.16 11.2 1.4 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term GatB_N PF02934.10 AET41000.1 - 4.9e-92 307.8 0.0 6.4e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AET41000.1 - 1.8e-27 95.9 0.0 3e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 GatB domain PUF PF00806.14 AET41001.1 - 2.5e-28 95.9 4.6 9.3e-05 21.7 0.0 7.2 7 0 0 7 7 7 6 Pumilio-family RNA binding repeat RRM_1 PF00076.17 AET41001.1 - 7.5e-07 28.7 0.0 1.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET41001.1 - 3.8e-06 26.6 0.0 8.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET41001.1 - 0.084 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Anillin PF08174.6 AET41002.1 - 2.6e-09 37.2 0.8 2.2e-08 34.2 0.0 2.8 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 AET41002.1 - 3.7e-06 27.0 0.0 1.9e-05 24.8 0.0 2.4 1 0 0 1 1 1 1 PH domain Fip1 PF05182.8 AET41003.1 - 2.3e-23 81.1 0.6 4.5e-23 80.2 0.4 1.5 1 0 0 1 1 1 1 Fip1 motif Daxx PF03344.10 AET41003.1 - 0.039 12.4 12.4 0.061 11.8 8.6 1.4 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 AET41003.1 - 1.1 7.0 16.8 1.5 6.6 11.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AET41003.1 - 1.4 6.8 6.5 1.9 6.3 4.5 1.3 1 0 0 1 1 1 0 CDC45-like protein BAF1_ABF1 PF04684.8 AET41004.1 - 7.7 5.2 11.1 11 4.7 7.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_L37ae PF01780.14 AET41005.1 - 7.8e-40 134.6 9.2 8.9e-40 134.4 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 AET41005.1 - 0.01 15.5 0.4 0.012 15.3 0.3 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain Zn_Tnp_IS1595 PF12760.2 AET41005.1 - 0.014 15.2 2.6 0.026 14.3 1.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF1364 PF07102.7 AET41005.1 - 0.017 14.9 1.0 0.023 14.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Sgf11 PF08209.6 AET41005.1 - 0.035 13.4 0.9 0.63 9.4 0.0 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CarbpepA_inh PF02977.10 AET41005.1 - 0.085 12.4 3.0 0.54 9.8 2.1 2.2 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.1 AET41005.1 - 0.11 12.8 0.8 2.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain C1_1 PF00130.17 AET41005.1 - 0.12 12.1 1.8 0.2 11.4 1.2 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 AET41005.1 - 0.14 11.8 2.9 0.23 11.1 1.9 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-C4_ClpX PF06689.8 AET41005.1 - 0.15 11.5 0.3 0.15 11.5 0.2 2.4 3 0 0 3 3 3 0 ClpX C4-type zinc finger Elf1 PF05129.8 AET41005.1 - 0.22 11.2 3.0 0.55 9.9 2.1 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Mito_carr PF00153.22 AET41006.1 - 3.2e-72 238.3 1.2 4.1e-24 84.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.16 AET41008.1 - 3.8e-46 157.1 0.0 5.2e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PX PF00787.19 AET41009.1 - 1.6e-10 40.7 0.0 3.6e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 AET41009.1 - 0.0012 18.2 0.2 0.0035 16.7 0.1 1.8 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AET41009.1 - 0.006 15.9 0.0 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 SH3 domain Peptidase_C12 PF01088.16 AET41010.1 - 5.1e-49 166.3 0.0 6.2e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SAC3_GANP PF03399.11 AET41011.1 - 1.8e-50 171.3 6.4 2.9e-50 170.6 4.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 AET41011.1 - 9.9e-05 22.1 0.7 0.00022 21.0 0.5 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Sod_Fe_C PF02777.13 AET41012.1 - 2.6e-10 40.0 0.4 0.00059 19.6 0.1 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Amidoligase_2 PF12224.3 AET41012.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme ESCRT-II PF05871.7 AET41013.1 - 1.9e-42 144.4 2.2 2.7e-42 144.0 1.4 1.3 2 0 0 2 2 2 1 ESCRT-II complex subunit CTP_synth_N PF06418.9 AET41015.1 - 8.1e-120 399.0 0.1 1.1e-119 398.5 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 AET41015.1 - 5.7e-58 195.5 0.0 8.5e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AET41015.1 - 0.0002 20.8 0.0 0.00058 19.3 0.0 1.8 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 AET41015.1 - 0.0021 17.5 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Sod_Cu PF00080.15 AET41016.1 - 5.9e-47 159.3 3.6 7.1e-47 159.1 2.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Thioredoxin PF00085.15 AET41017.1 - 3.4e-16 58.7 0.0 8.4e-12 44.6 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_8 PF13905.1 AET41017.1 - 1.8e-05 24.7 0.0 0.012 15.7 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 AET41017.1 - 0.0018 18.1 0.0 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 AET41017.1 - 0.019 15.1 0.1 0.41 10.8 0.0 2.7 2 1 0 2 2 2 0 Thioredoxin-like domain TraF PF13728.1 AET41017.1 - 0.17 11.3 0.0 0.4 10.1 0.0 1.6 1 0 0 1 1 1 0 F plasmid transfer operon protein ER_lumen_recept PF00810.13 AET41018.1 - 1.1e-51 175.2 12.7 1.7e-51 174.6 8.8 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 AET41018.1 - 0.042 13.3 0.6 0.042 13.3 0.4 3.3 4 0 0 4 4 4 0 PQ loop repeat DUF4564 PF15169.1 AET41018.1 - 1.2 8.8 7.2 0.48 10.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) Proteasome PF00227.21 AET41019.1 - 8.7e-38 129.5 0.1 4.6e-37 127.1 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit Peptidase_M20 PF01546.23 AET41020.1 - 4.5e-22 78.4 0.0 6.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AET41020.1 - 2.4e-10 40.1 0.0 5.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF4433 PF14487.1 AET41020.1 - 0.018 14.8 0.1 0.047 13.4 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4433) Daxx PF03344.10 AET41021.1 - 0.078 11.4 8.9 0.093 11.1 6.2 1.0 1 0 0 1 1 1 0 Daxx Family AF-4 PF05110.8 AET41021.1 - 0.43 8.3 7.6 0.63 7.8 5.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_M16_C PF05193.16 AET41022.1 - 1.2e-24 87.0 0.0 2.4e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AET41022.1 - 6.2e-17 61.7 2.5 2e-16 60.0 1.7 1.8 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) DUF3110 PF11360.3 AET41022.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) PPP4R2 PF09184.6 AET41023.1 - 9.4e-46 156.6 1.5 9.4e-46 156.6 1.0 2.9 1 1 1 3 3 3 1 PPP4R2 Daxx PF03344.10 AET41023.1 - 0.029 12.9 19.9 0.041 12.3 13.8 1.2 1 0 0 1 1 1 0 Daxx Family TEX19 PF15553.1 AET41023.1 - 2.1 8.1 7.4 4.5 7.1 5.1 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 Nop14 PF04147.7 AET41023.1 - 2.3 6.0 30.1 3.2 5.5 20.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AET41023.1 - 8.8 4.2 14.4 12 3.7 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S7 PF00177.16 AET41024.1 - 1.5e-32 112.2 0.6 2.7e-32 111.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e VanZ PF04892.7 AET41025.1 - 6.7e-07 29.3 1.1 1.1e-06 28.6 0.0 1.8 2 1 0 2 2 2 1 VanZ like family EF-hand_4 PF12763.2 AET41026.1 - 4.3e-32 109.9 0.1 3.3e-09 36.4 0.0 4.4 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 AET41026.1 - 5.4e-11 42.4 0.0 0.08 13.0 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain pair UBA PF00627.26 AET41026.1 - 1.3e-10 40.7 0.1 4.1e-10 39.1 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 AET41026.1 - 5.8e-08 31.9 0.1 0.57 10.2 0.0 4.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 AET41026.1 - 1.3e-07 30.4 0.1 0.15 11.4 0.0 4.3 4 0 0 4 4 4 3 EF hand UBA_4 PF14555.1 AET41026.1 - 0.00025 20.5 0.2 0.00066 19.1 0.2 1.8 1 0 0 1 1 1 1 UBA-like domain Tropomyosin_1 PF12718.2 AET41026.1 - 0.005 16.6 23.9 0.005 16.6 16.5 4.0 2 1 2 4 4 4 1 Tropomyosin like TPR_MLP1_2 PF07926.7 AET41026.1 - 0.0075 16.0 28.5 0.0075 16.0 19.8 4.1 1 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein DUF1515 PF07439.6 AET41026.1 - 2.1 8.2 7.4 2 8.2 0.0 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1515) DUF3584 PF12128.3 AET41026.1 - 2.6 5.2 56.1 5.2 4.2 38.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nnf1 PF03980.9 AET41027.1 - 2.5e-26 91.8 6.4 2.5e-26 91.8 4.4 1.6 2 0 0 2 2 2 1 Nnf1 bZIP_1 PF00170.16 AET41027.1 - 0.0014 18.5 2.4 0.0014 18.5 1.7 2.5 3 0 0 3 3 3 1 bZIP transcription factor Baculo_PEP_C PF04513.7 AET41027.1 - 0.021 14.6 1.3 0.034 13.9 0.1 2.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 AET41027.1 - 0.031 14.1 0.3 0.11 12.4 0.2 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MbeB_N PF04837.7 AET41027.1 - 0.16 12.1 2.0 0.91 9.6 0.2 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region DUF4164 PF13747.1 AET41027.1 - 0.21 11.7 0.4 0.21 11.7 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) CMD PF02627.15 AET41028.1 - 2.5e-05 24.0 0.0 0.00019 21.2 0.0 2.4 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Myotub-related PF06602.9 AET41029.1 - 1.1e-131 438.7 2.0 1.5e-131 438.3 1.4 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 AET41029.1 - 0.0027 17.0 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 AET41029.1 - 0.0097 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 AET41029.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family GRAM PF02893.15 AET41029.1 - 0.024 14.1 0.1 0.078 12.5 0.0 1.9 2 0 0 2 2 2 0 GRAM domain Yippee-Mis18 PF03226.9 AET41030.1 - 6.1e-19 67.8 2.1 8e-19 67.4 1.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NinF PF05810.7 AET41030.1 - 0.11 12.3 0.2 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 NinF protein zf-UBP PF02148.14 AET41030.1 - 2.8 8.1 6.7 15 5.8 4.6 1.9 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein NAD_binding_6 PF08030.7 AET41031.1 - 3e-23 82.4 0.0 5e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AET41031.1 - 1.2e-20 73.3 0.2 3.8e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 AET41031.1 - 3.9e-16 59.2 15.4 3.9e-16 59.2 10.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component SNAP PF14938.1 AET41032.1 - 5e-105 350.6 11.3 5.7e-105 350.5 7.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 AET41032.1 - 1.3e-05 24.7 13.3 0.0025 17.4 0.1 3.6 1 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 AET41032.1 - 4.2e-05 23.1 9.2 1.6 8.8 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 AET41032.1 - 0.00013 22.2 8.4 0.48 10.9 0.2 5.8 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 AET41032.1 - 0.00026 20.8 12.8 1.1 9.2 0.8 4.2 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 AET41032.1 - 0.0016 19.0 7.9 0.015 15.9 0.3 3.5 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 AET41032.1 - 0.0043 17.5 7.1 0.029 14.9 0.1 4.5 5 1 1 6 6 4 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 AET41032.1 - 0.0069 15.8 1.6 0.45 9.9 0.1 2.7 1 1 1 3 3 3 1 Foie gras liver health family 1 TPR_19 PF14559.1 AET41032.1 - 0.0088 16.3 2.0 0.0088 16.3 1.4 3.8 4 2 1 5 5 5 1 Tetratricopeptide repeat Rapamycin_bind PF08771.6 AET41032.1 - 0.027 14.5 0.1 0.1 12.7 0.1 1.9 1 0 0 1 1 1 0 Rapamycin binding domain Apc3 PF12895.2 AET41032.1 - 0.058 13.5 11.2 0.31 11.1 2.5 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AET41032.1 - 0.18 11.6 14.3 14 5.7 0.0 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 AET41032.1 - 0.29 10.8 14.2 1.7 8.4 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 AET41032.1 - 4.9 7.1 12.6 12 5.8 0.5 4.8 5 2 0 5 5 5 0 MIT (microtubule interacting and transport) domain OPT PF03169.10 AET41033.1 - 1.1e-181 605.5 55.6 1.2e-181 605.3 38.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CPSase_L_D2 PF02786.12 AET41034.1 - 1.3e-107 357.8 0.0 3.3e-83 278.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 AET41034.1 - 4.9e-39 132.9 0.1 9.2e-39 132.0 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AET41034.1 - 8.9e-39 133.1 0.0 3.7e-21 75.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 AET41034.1 - 1.5e-37 128.0 0.0 2.2e-18 66.3 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 AET41034.1 - 2e-25 89.2 0.0 2.1e-10 39.8 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AET41034.1 - 1.9e-19 69.6 0.0 2.2e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AET41034.1 - 1.6e-14 53.7 0.1 4.3e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 AET41034.1 - 4.3e-08 32.8 0.0 0.00013 21.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain MGS PF02142.17 AET41034.1 - 0.00011 22.0 0.0 0.00061 19.6 0.0 2.3 3 0 0 3 3 3 1 MGS-like domain ATP-grasp_5 PF13549.1 AET41034.1 - 0.00026 20.2 0.2 0.016 14.4 0.1 2.4 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 AET41034.1 - 0.00063 19.3 0.1 0.51 9.8 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain G-alpha PF00503.15 AET41035.1 - 4.6e-112 374.5 0.0 5.4e-112 374.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AET41035.1 - 2.7e-14 52.7 1.0 4.6e-10 39.0 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET41035.1 - 6.9e-05 22.0 1.8 0.0064 15.6 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 AET41035.1 - 0.00031 21.2 0.2 0.98 9.9 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 AET41035.1 - 0.078 12.4 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.17 AET41035.1 - 0.11 11.8 0.3 11 5.3 0.1 2.6 2 1 0 2 2 2 0 Ras family MMR_HSR1 PF01926.18 AET41035.1 - 0.12 12.3 0.2 2.8 7.9 0.1 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Lipase_3 PF01764.20 AET41036.1 - 2.2e-38 131.0 0.0 3.8e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 AET41036.1 - 0.044 13.1 0.0 9.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Na_Ca_ex PF01699.19 AET41037.1 - 4.5e-46 155.9 34.8 1.5e-27 95.8 7.0 3.3 3 1 1 4 4 4 2 Sodium/calcium exchanger protein PfkB PF00294.19 AET41038.1 - 4.5e-67 226.2 0.1 6.3e-67 225.8 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 AET41038.1 - 0.0039 16.4 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TRAM_LAG1_CLN8 PF03798.11 AET41039.1 - 1e-28 100.2 20.6 1e-28 100.2 14.3 1.7 2 0 0 2 2 2 1 TLC domain DUF3611 PF12263.3 AET41039.1 - 0.0017 17.7 2.1 0.0043 16.4 1.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3611) Peptidase_M48 PF01435.13 AET41040.1 - 3.1e-46 157.7 0.0 4.6e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M43 PF05572.8 AET41040.1 - 0.058 12.9 0.1 0.098 12.2 0.1 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF2268 PF10026.4 AET41040.1 - 0.087 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Rpn3_C PF08375.6 AET41041.1 - 1.1e-20 73.8 0.6 2.7e-20 72.5 0.2 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 AET41041.1 - 1.8e-19 69.9 0.2 1.8e-19 69.9 0.1 2.3 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 AET41041.1 - 0.0023 17.6 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 MarR_2 PF12802.2 AET41041.1 - 0.007 16.0 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 MarR family TPR_2 PF07719.12 AET41041.1 - 0.34 10.9 1.7 9.2 6.4 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Med17 PF10156.4 AET41042.1 - 2.3e-131 438.2 11.6 2.8e-131 438.0 8.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ilm1 PF10311.4 AET41043.1 - 5.6e-39 133.2 11.4 8.3e-39 132.7 7.9 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF3487 PF11990.3 AET41043.1 - 0.0014 17.9 1.6 0.0093 15.3 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3487) JmjC PF02373.17 AET41044.1 - 4.1e-39 133.3 0.8 9.2e-39 132.2 0.6 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 AET41044.1 - 7.1e-10 38.4 5.8 7.1e-10 38.4 4.0 2.2 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.12 AET41044.1 - 2.5e-09 36.4 0.2 2.1e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 jmjN domain Prok-RING_1 PF14446.1 AET41044.1 - 0.016 14.8 0.7 0.056 13.1 0.5 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 AET41044.1 - 0.021 14.5 5.8 0.054 13.2 0.9 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.1 AET41044.1 - 0.055 13.4 1.9 0.11 12.4 0.7 2.0 1 1 0 1 1 1 0 PHD-zinc-finger like domain PHD_2 PF13831.1 AET41044.1 - 0.097 12.0 6.4 0.037 13.3 1.2 2.7 3 0 0 3 3 3 0 PHD-finger zf-RING_2 PF13639.1 AET41044.1 - 0.19 11.5 10.0 0.45 10.3 5.2 2.6 2 0 0 2 2 2 0 Ring finger domain zf-HC5HC2H PF13771.1 AET41044.1 - 0.88 9.7 4.9 0.45 10.7 1.1 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 AET41044.1 - 3.1 7.8 7.4 10 6.1 5.1 2.0 1 0 0 1 1 1 0 RING-like domain P5CR_dimer PF14748.1 AET41045.1 - 1.1e-32 112.1 0.1 1.9e-32 111.4 0.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 AET41045.1 - 1.8e-12 47.5 0.1 4.4e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 AET41045.1 - 0.0022 16.9 0.2 0.0081 15.0 0.1 1.7 2 1 0 3 3 3 1 Prephenate dehydrogenase ApbA PF02558.11 AET41045.1 - 0.0025 17.2 1.1 0.0054 16.1 0.2 1.9 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 AET41045.1 - 0.0025 17.5 1.8 0.0072 16.0 1.2 1.9 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ATP-synt_ab PF00006.20 AET41046.1 - 2.6e-63 213.4 0.0 4e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AET41046.1 - 2.2e-26 92.5 0.2 4e-26 91.7 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AET41046.1 - 2.7e-25 88.3 1.8 7.3e-25 86.9 1.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 AET41046.1 - 0.00084 18.5 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AET41046.1 - 0.004 16.5 0.0 0.011 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 AET41046.1 - 0.0065 16.1 0.1 0.53 9.9 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 AET41046.1 - 0.011 14.5 0.6 0.52 9.1 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 AET41046.1 - 0.022 14.4 0.1 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 AET41046.1 - 0.039 13.9 0.7 0.18 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 AET41046.1 - 0.049 13.8 0.0 0.55 10.4 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AET41046.1 - 0.056 12.6 0.1 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 AET41046.1 - 0.089 12.9 0.1 0.37 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AET41046.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 AET41046.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase GCV_T PF01571.16 AET41047.1 - 6.2e-07 28.9 0.0 0.0084 15.4 0.0 2.4 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 AET41047.1 - 0.044 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Ribosomal_S7 PF00177.16 AET41048.1 - 1.3e-39 135.1 1.9 1.8e-39 134.7 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Carn_acyltransf PF00755.15 AET41049.1 - 2.9e-75 253.5 0.0 4.1e-62 210.1 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase MFS_1 PF07690.11 AET41050.1 - 8.1e-25 87.2 27.8 1e-15 57.3 3.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AET41050.1 - 4.4e-06 25.3 27.3 8.2e-06 24.4 3.3 2.8 2 1 1 3 3 3 3 MFS/sugar transport protein ATG22 PF11700.3 AET41050.1 - 9.4e-06 24.3 11.2 9.4e-06 24.3 7.8 2.5 3 0 0 3 3 3 1 Vacuole effluxer Atg22 like OATP PF03137.15 AET41050.1 - 0.00027 19.1 2.9 0.00027 19.1 2.0 3.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 AET41050.1 - 0.00088 19.0 4.4 0.0094 15.7 0.3 4.0 4 0 0 4 4 4 1 MFS_1 like family Zn_clus PF00172.13 AET41051.1 - 2.4e-08 33.7 9.5 4.8e-08 32.7 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.22 AET41052.1 - 4.7e-39 133.7 0.0 9.3e-39 132.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 AET41052.1 - 1.8e-36 124.0 0.2 4e-36 122.9 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 AET41052.1 - 1e-09 38.3 2.5 1.2e-09 38.1 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AET41052.1 - 0.0065 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AET41052.1 - 0.071 12.9 0.4 0.94 9.2 0.0 2.8 3 0 0 3 3 3 0 Dynamin family Connexin_CCC PF10582.4 AET41052.1 - 1.3 8.8 3.6 1.4 8.7 1.7 1.7 1 1 0 1 1 1 0 Gap junction channel protein cysteine-rich domain RGS PF00615.14 AET41053.1 - 7.7e-18 64.7 0.6 1.6e-10 41.0 0.1 3.0 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.16 AET41053.1 - 5.4e-13 48.4 0.0 7.6e-12 44.8 0.0 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.20 AET41054.1 - 4.7e-72 242.2 0.0 6.3e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41054.1 - 1.1e-31 109.9 0.0 7.4e-31 107.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET41054.1 - 0.037 12.9 0.0 0.088 11.7 0.0 1.6 1 1 0 1 1 1 0 Kinase-like ORC4_C PF14629.1 AET41055.1 - 3.5e-35 121.2 3.8 7.7e-35 120.1 2.6 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.24 AET41055.1 - 0.031 14.4 0.0 0.031 14.4 0.0 3.0 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) T4_gp9_10 PF07880.6 AET41055.1 - 0.12 11.3 1.8 0.2 10.6 1.0 1.5 1 1 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein Glyco_tran_28_C PF04101.11 AET41055.1 - 0.13 11.9 3.5 2.9 7.5 0.2 2.8 1 1 1 2 2 2 0 Glycosyltransferase family 28 C-terminal domain RRM_6 PF14259.1 AET41056.1 - 2.8e-10 40.0 0.0 4.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET41056.1 - 1.9e-09 37.0 0.0 3.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET41056.1 - 0.001 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_UL7 PF01677.11 AET41056.1 - 0.062 12.6 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL7 like Ras PF00071.17 AET41058.1 - 1.7e-53 180.3 0.0 2e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET41058.1 - 5.3e-15 55.9 0.0 8.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET41058.1 - 5.2e-08 32.3 0.0 7.9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET41058.1 - 0.084 11.9 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.17 AET41059.1 - 5.1e-55 185.2 0.0 6e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET41059.1 - 1.8e-16 60.7 0.0 2.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET41059.1 - 7.1e-07 28.6 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AET41059.1 - 9e-05 21.9 0.0 0.00038 19.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AET41059.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.16 AET41060.1 - 1.3e-20 72.5 0.3 2e-20 71.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e SAP30_Sin3_bdg PF13867.1 AET41060.1 - 0.077 12.8 1.5 0.21 11.4 0.2 2.1 1 1 1 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 SSF PF00474.12 AET41062.1 - 4.2e-10 38.8 29.0 9.9e-10 37.6 20.1 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family DUF2839 PF10999.3 AET41062.1 - 2.7 8.0 4.7 6.3 6.9 0.4 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) CBFD_NFYB_HMF PF00808.18 AET41063.1 - 3.7e-12 46.1 0.2 6.6e-12 45.3 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AET41063.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 SecE PF00584.15 AET41064.1 - 1.2e-10 40.7 0.0 1.3e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF3603 PF12227.3 AET41064.1 - 0.12 11.5 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Nop52 PF05997.7 AET41065.1 - 1.5e-65 220.6 2.7 1.8e-65 220.4 1.9 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 AET41065.1 - 0.012 15.2 0.4 0.078 12.7 0.1 2.2 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair TRAUB PF08164.7 AET41065.1 - 0.02 15.0 0.2 0.041 13.9 0.1 1.5 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Arm PF00514.18 AET41065.1 - 0.076 12.8 0.1 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Slu7 PF11708.3 AET41066.1 - 1.3e-32 113.4 1.8 2.1e-32 112.8 1.2 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 AET41066.1 - 0.05 13.2 3.3 0.11 12.1 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 AET41066.1 - 0.46 10.4 5.4 0.95 9.5 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle SPX PF03105.14 AET41067.1 - 5e-08 33.0 0.5 5e-08 33.0 0.3 3.4 2 2 1 3 3 3 2 SPX domain Cation_ATPase_C PF00689.16 AET41067.1 - 0.45 10.0 8.0 0.75 9.2 5.6 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF997 PF06196.7 AET41067.1 - 2.6 7.6 7.3 6.4 6.3 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF997) SPT2 PF08243.6 AET41068.1 - 1.2e-23 83.6 23.9 1.2e-23 83.6 16.6 2.5 3 0 0 3 3 3 1 SPT2 chromatin protein Rad4 PF03835.10 AET41069.1 - 2.1e-35 121.2 1.0 2.1e-35 121.2 0.7 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 AET41069.1 - 5.5e-25 86.8 0.4 1.5e-24 85.4 0.1 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 AET41069.1 - 5.3e-19 67.4 0.0 1.3e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 AET41069.1 - 2.6e-10 40.4 0.0 9.2e-10 38.6 0.0 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 AET41069.1 - 0.00018 21.6 0.1 0.00068 19.8 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily CK_II_beta PF01214.13 AET41070.1 - 8.3e-73 243.8 0.0 1.1e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.8 AET41071.1 - 1.3e-19 70.4 3.4 2.5e-19 69.4 2.4 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 AET41071.1 - 3.8e-08 32.9 0.0 1.5e-07 31.0 0.0 2.1 2 1 0 2 2 2 1 DnaJ domain Wbp11 PF09429.5 AET41071.1 - 0.0089 15.9 1.8 0.016 15.1 0.8 1.7 2 0 0 2 2 2 1 WW domain binding protein 11 Skp1 PF01466.14 AET41071.1 - 0.08 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain DUF3782 PF12644.2 AET41071.1 - 0.21 11.3 1.9 0.48 10.2 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) ATE_C PF04377.10 AET41072.1 - 7.1e-43 145.7 1.1 1.5e-42 144.7 0.7 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 AET41072.1 - 4.4e-23 80.8 0.2 1.1e-22 79.5 0.2 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Aminotran_1_2 PF00155.16 AET41074.1 - 2e-17 63.2 0.0 2.6e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 AET41074.1 - 0.051 12.5 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.27 AET41075.1 - 4.9e-43 143.5 8.6 4.4e-10 39.0 0.0 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Hira PF07569.6 AET41075.1 - 8.4e-10 38.2 0.1 3.7e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split HIRA_B PF09453.5 AET41075.1 - 8.6e-08 31.5 0.0 2.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 HIRA B motif IKI3 PF04762.7 AET41075.1 - 0.02 12.7 0.0 0.53 8.0 0.0 2.3 2 0 0 2 2 2 0 IKI3 family Toxin_37 PF11415.3 AET41075.1 - 1.6 8.4 5.9 2 8.1 0.6 2.6 2 0 0 2 2 2 0 Antifungal peptide termicin Aconitase PF00330.15 AET41076.1 - 3.8e-191 635.5 0.0 4.8e-191 635.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AET41076.1 - 3.6e-45 153.2 0.0 2.1e-44 150.8 0.0 2.3 3 0 0 3 3 3 1 Aconitase C-terminal domain SH3_1 PF00018.23 AET41077.1 - 8.5e-37 124.3 4.8 1.1e-11 43.8 0.1 4.5 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 AET41077.1 - 1.1e-33 114.5 6.8 4.2e-11 42.2 0.2 4.6 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.7 AET41077.1 - 2.8e-32 110.1 0.9 5.7e-32 109.1 0.1 2.0 2 0 0 2 2 2 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 AET41077.1 - 1.1e-26 92.0 1.0 3.9e-07 29.4 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF3104 PF11302.3 AET41077.1 - 0.002 17.4 0.1 0.0086 15.4 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3104) DUF1720 PF08226.6 AET41077.1 - 2.2 8.4 113.1 6 7.0 7.9 7.7 1 1 4 5 5 5 0 Domain of unknown function (DUF1720) DUF962 PF06127.6 AET41078.1 - 6.6e-22 77.2 6.2 2.3e-21 75.4 4.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ATP_synt_H PF05493.8 AET41078.1 - 1.3 9.1 6.2 0.8 9.8 2.4 2.0 2 0 0 2 2 2 0 ATP synthase subunit H Proteasome PF00227.21 AET41079.1 - 1.8e-46 157.8 0.0 2.6e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AET41079.1 - 2e-15 55.7 0.1 3.3e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rsc14 PF08586.5 AET41080.1 - 5.6e-36 123.0 0.1 7.6e-36 122.6 0.1 1.2 1 0 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit Gag_p17 PF00540.13 AET41080.1 - 0.03 14.0 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) Fungal_trans PF04082.13 AET41081.1 - 3e-14 52.5 2.0 6.5e-14 51.4 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET41081.1 - 2.1e-06 27.5 15.3 5.7e-06 26.1 10.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUF PF00806.14 AET41082.1 - 2.9e-62 202.7 9.5 1.3e-08 33.8 0.3 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Dpoe2NT PF12213.3 AET41082.1 - 0.025 14.4 0.2 1.1 9.2 0.0 2.8 2 1 0 2 2 2 0 DNA polymerases epsilon N terminal TnpB_IS66 PF05717.8 AET41082.1 - 0.19 11.1 0.0 0.48 9.8 0.0 1.6 1 0 0 1 1 1 0 IS66 Orf2 like protein Toxin_17 PF08086.6 AET41082.1 - 0.22 11.6 2.6 0.54 10.3 1.8 1.6 1 0 0 1 1 1 0 Ergtoxin family E1-E2_ATPase PF00122.15 AET41083.1 - 3.4e-64 216.0 5.5 7.2e-64 214.9 3.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AET41083.1 - 3e-23 83.3 0.0 6.1e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AET41083.1 - 4.5e-14 53.0 0.0 1.1e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AET41083.1 - 3.4e-12 45.6 0.1 1.4e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AET41083.1 - 0.0012 18.4 0.1 0.0026 17.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AET41083.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Zn_clus PF00172.13 AET41084.1 - 4.7e-07 29.6 13.5 9.3e-07 28.6 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 AET41084.1 - 0.043 12.6 14.3 0.075 11.8 9.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UDPGP PF01704.13 AET41085.1 - 6.6e-189 627.7 0.0 8.3e-189 627.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 AET41085.1 - 0.0051 15.4 0.1 0.02 13.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4301) zf-RING_2 PF13639.1 AET41086.1 - 2.8e-11 43.0 4.9 5.7e-11 42.0 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AET41086.1 - 4.6e-08 33.0 4.8 1e-07 31.9 3.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AET41086.1 - 1.6e-07 30.9 3.5 2.8e-07 30.1 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AET41086.1 - 2.7e-06 26.9 6.4 5.4e-06 25.9 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AET41086.1 - 3.8e-06 26.4 6.3 7.5e-06 25.5 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET41086.1 - 6.3e-06 26.1 3.0 6.3e-06 26.1 2.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AET41086.1 - 0.003 17.3 1.2 0.0067 16.2 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 AET41086.1 - 0.0045 16.6 1.5 0.013 15.2 1.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 AET41086.1 - 0.035 14.0 5.0 0.14 12.1 3.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain HAD_2 PF13419.1 AET41087.1 - 1.8e-18 67.3 0.0 2.3e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AET41087.1 - 1e-10 42.4 0.0 1.3e-10 42.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AET41087.1 - 7e-06 25.8 0.0 4.9e-05 23.1 0.0 2.3 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 AET41087.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pribosyl_synth PF14572.1 AET41088.1 - 4.4e-40 137.3 3.3 5.9e-35 120.6 1.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 AET41088.1 - 3.1e-39 133.3 1.4 1.8e-38 130.8 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 AET41088.1 - 6.5e-12 45.2 0.7 1.6e-11 43.9 0.4 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AET41088.1 - 0.0032 16.6 0.2 0.0056 15.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BRAP2 PF07576.7 AET41089.1 - 3.9e-24 84.3 0.1 1.1e-23 82.9 0.1 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 AET41089.1 - 8.3e-22 77.0 8.6 3.9e-21 74.9 5.9 2.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 AET41089.1 - 6e-10 38.8 9.8 6e-10 38.8 6.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 AET41089.1 - 2.9e-06 26.9 7.5 2.9e-06 26.9 5.2 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AET41089.1 - 2.1e-05 24.0 19.3 0.00046 19.8 4.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AET41089.1 - 6.5e-05 22.8 8.1 6.5e-05 22.8 5.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AET41089.1 - 0.00034 20.6 4.7 0.00034 20.6 3.2 2.9 3 0 0 3 3 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AET41089.1 - 0.00041 20.1 4.4 0.0016 18.2 3.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 AET41089.1 - 0.00059 19.4 7.8 0.00059 19.4 5.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AET41089.1 - 0.0016 18.0 1.8 0.0016 18.0 1.3 3.8 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 AET41089.1 - 0.011 15.3 7.6 0.011 15.3 5.3 2.0 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain HALZ PF02183.13 AET41089.1 - 0.019 14.6 1.1 0.019 14.6 0.7 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1664 PF07889.7 AET41089.1 - 0.15 11.8 4.1 0.23 11.2 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 AET41089.1 - 0.2 11.3 13.4 0.17 11.5 2.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 AET41089.1 - 0.2 11.8 2.6 0.49 10.5 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.14 AET41089.1 - 0.24 9.2 7.3 0.34 8.7 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 AET41089.1 - 0.27 10.9 9.5 0.6 9.8 1.9 2.2 1 1 1 2 2 2 0 Laminin Domain II DivIC PF04977.10 AET41089.1 - 0.71 9.3 5.7 2.8 7.4 0.7 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF4404 PF14357.1 AET41089.1 - 0.99 9.8 5.8 0.23 11.8 1.5 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4404) ADIP PF11559.3 AET41089.1 - 1.2 9.0 15.6 5.9 6.7 3.5 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 AET41089.1 - 1.6 8.2 11.7 3.4 7.2 8.1 1.5 1 0 0 1 1 1 0 IncA protein zf-RING_6 PF14835.1 AET41089.1 - 1.7 8.4 7.5 1.1 9.1 3.0 2.4 2 1 0 2 2 1 0 zf-RING of BARD1-type protein Cortex-I_coil PF09304.5 AET41089.1 - 3.7 7.6 10.5 2.9 7.9 4.1 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil Form_Nir_trans PF01226.12 AET41090.1 - 1.1e-64 217.6 24.9 1.5e-64 217.2 17.3 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter Val_tRNA-synt_C PF10458.4 AET41090.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm HEAT PF02985.17 AET41091.1 - 2.3e-05 24.0 0.1 6.2 7.1 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat FANCI_S2 PF14676.1 AET41091.1 - 0.00014 21.7 1.0 0.28 11.0 0.0 4.4 4 0 0 4 4 4 1 FANCI solenoid 2 HEAT_2 PF13646.1 AET41091.1 - 0.00067 19.8 0.0 0.48 10.7 0.0 4.2 4 1 1 5 5 5 2 HEAT repeats Phage_Orf51 PF06194.6 AET41091.1 - 0.1 12.7 1.2 0.44 10.6 0.1 2.3 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 PHD PF00628.24 AET41092.1 - 9.5e-16 57.2 19.8 2.5e-10 39.9 5.4 3.1 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 AET41092.1 - 0.016 14.5 11.1 0.38 10.1 0.1 3.8 3 0 0 3 3 3 0 PHD-finger zf-PHD-like PF15446.1 AET41092.1 - 0.044 13.0 10.2 0.072 12.3 0.2 3.1 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 AET41092.1 - 0.053 13.6 7.2 0.09 12.9 1.2 2.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.17 AET41092.1 - 0.19 11.4 9.8 2.2 8.0 1.6 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) dsDNA_bind PF01984.15 AET41093.1 - 1.5e-24 86.0 7.7 6.5e-24 83.9 5.3 1.7 1 1 0 1 1 1 1 Double-stranded DNA-binding domain Transket_pyr PF02779.19 AET41093.1 - 0.015 14.8 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain TetR_C_2 PF08361.6 AET41093.1 - 0.13 12.1 0.1 1 9.2 0.0 2.0 1 1 1 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region Cu_amine_oxid PF01179.15 AET41094.1 - 2.9e-149 497.3 0.1 3.5e-149 497.0 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 AET41094.1 - 0.00023 21.1 0.0 0.001 19.1 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cyt-b5 PF00173.23 AET41095.1 - 8.7e-13 47.8 0.0 1.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HMG_box PF00505.14 AET41096.1 - 1.2e-33 115.2 12.5 5.6e-18 64.9 3.2 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 AET41096.1 - 8.2e-18 64.5 8.0 2e-11 44.1 2.3 3.3 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.7 AET41096.1 - 0.00028 20.4 0.0 0.53 10.0 0.0 2.5 2 0 0 2 2 2 2 CHDNT (NUC034) domain DUF1413 PF07205.6 AET41096.1 - 0.1 12.1 2.0 0.86 9.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) DUF1911 PF08929.5 AET41096.1 - 0.16 12.6 7.3 0.54 10.9 5.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Hph PF13694.1 AET41096.1 - 0.24 11.3 9.5 0.041 13.9 3.7 1.7 2 0 0 2 2 2 0 Sec63/Sec62 complex-interacting family Herpes_env PF01673.13 AET41096.1 - 0.71 8.3 7.6 1.2 7.5 5.3 1.4 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein zinc_ribbon_6 PF14599.1 AET41097.1 - 6e-24 83.6 3.0 6e-24 83.6 2.1 3.5 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 AET41097.1 - 2.3e-12 46.8 17.2 2.3e-12 46.8 11.9 4.5 2 1 2 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 AET41097.1 - 1.8e-07 30.8 9.1 1.8e-07 30.8 6.3 4.9 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 AET41097.1 - 0.00012 21.9 7.4 0.00012 21.9 5.1 5.3 3 3 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AET41097.1 - 0.0028 17.3 11.5 0.0028 17.3 8.0 6.5 5 3 1 6 6 6 2 zinc-RING finger domain Cg6151-P PF10233.4 AET41098.1 - 6.4e-35 119.5 12.3 8.1e-35 119.2 8.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PRA1 PF03208.14 AET41098.1 - 0.11 11.7 6.1 0.16 11.3 4.2 1.2 1 0 0 1 1 1 0 PRA1 family protein zf-C2H2 PF00096.21 AET41099.1 - 0.00045 20.3 6.3 0.00045 20.3 4.4 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET41099.1 - 0.0018 18.4 20.3 0.0034 17.6 3.7 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AET41099.1 - 1.1 9.6 19.0 1.5 9.2 1.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain LMBR1 PF04791.11 AET41099.1 - 3.8 5.9 7.4 6.1 5.3 5.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Acetyltransf_1 PF00583.19 AET41100.1 - 4.2e-13 49.1 0.0 1.3e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AET41100.1 - 1.9e-05 24.7 0.0 4.6e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AET41100.1 - 0.0018 18.0 0.0 0.0051 16.5 0.0 1.8 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AET41100.1 - 0.0043 17.1 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AET41100.1 - 0.03 14.4 0.0 0.091 12.9 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NIF PF03031.13 AET41101.1 - 4.5e-51 172.6 0.1 6e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2628 PF10947.3 AET41101.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) MFS_1 PF07690.11 AET41102.1 - 2.2e-37 128.5 16.5 2.7e-37 128.3 11.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AET41102.1 - 1e-12 47.4 8.2 1e-12 47.4 5.7 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Malic_M PF03949.10 AET41103.1 - 5.6e-74 248.9 0.0 7.4e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AET41103.1 - 2.4e-61 206.5 0.0 3.7e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TFIIE_alpha PF02002.12 AET41104.1 - 5.1e-29 99.8 0.1 5.1e-29 99.8 0.1 2.0 3 0 0 3 3 3 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 AET41104.1 - 5.3e-09 35.2 0.2 1.2e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding GntR PF00392.16 AET41104.1 - 0.042 13.3 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family ThiF PF00899.16 AET41105.1 - 1.2e-35 122.2 0.1 1.8e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 AET41105.1 - 0.00014 21.9 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 AET41105.1 - 0.002 18.1 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 AET41105.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 AET41105.1 - 0.024 13.6 0.1 0.056 12.4 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 AET41105.1 - 0.026 13.2 0.3 0.042 12.5 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 AET41105.1 - 0.041 13.2 0.3 0.091 12.1 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 AET41105.1 - 0.064 13.5 0.1 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding XdhC_C PF13478.1 AET41105.1 - 0.16 12.2 0.1 0.76 10.0 0.0 2.1 2 1 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.19 AET41105.1 - 0.54 9.0 1.5 1.3 7.8 1.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Mito_carr PF00153.22 AET41106.1 - 3.1e-60 199.8 0.0 1.3e-19 69.6 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 AET41107.1 - 1.4e-62 207.4 3.1 3.5e-23 81.1 0.7 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2370 PF10176.4 AET41108.1 - 9.4e-80 267.3 0.8 2.8e-79 265.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 AET41108.1 - 0.011 15.9 0.1 0.052 13.7 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) SNF5 PF04855.7 AET41109.1 - 4.1e-65 219.6 1.3 4.1e-65 219.6 0.9 4.0 3 1 0 3 3 3 1 SNF5 / SMARCB1 / INI1 Mem_trans PF03547.13 AET41109.1 - 0.019 13.3 1.2 0.021 13.1 0.8 1.2 1 0 0 1 1 1 0 Membrane transport protein Draxin PF15550.1 AET41109.1 - 0.75 9.3 18.3 1.9 8.0 12.7 1.7 1 0 0 1 1 1 0 Draxin Adap_comp_sub PF00928.16 AET41110.1 - 5e-28 97.9 0.0 7.1e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AET41110.1 - 0.0047 16.6 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain adh_short PF00106.20 AET41111.1 - 2.7e-67 225.8 10.0 5.9e-34 117.3 0.7 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 AET41111.1 - 1.1e-34 119.6 4.5 5.7e-17 61.9 0.4 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 AET41111.1 - 1.4e-24 85.8 0.0 3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 AET41111.1 - 3.8e-20 72.6 2.5 2.1e-11 44.0 0.2 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 AET41111.1 - 1.4e-05 24.8 0.0 4.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase DUF4397 PF14344.1 AET41111.1 - 0.028 14.7 0.4 14 6.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4397) DUF2099 PF09872.4 AET41111.1 - 0.039 12.9 0.5 0.081 11.9 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) 3HCDH_N PF02737.13 AET41111.1 - 1.4 8.5 7.3 2.7 7.5 0.2 3.2 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain QCR10 PF09796.4 AET41112.1 - 2.3e-28 97.6 0.9 3.4e-28 97.1 0.6 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 AET41112.1 - 0.0013 18.4 1.7 0.0034 17.0 1.2 1.7 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Rho_Binding PF08912.6 AET41113.1 - 0.016 15.4 9.6 0.016 15.4 6.6 4.9 3 1 1 4 4 4 0 Rho Binding Daxx PF03344.10 AET41114.1 - 0.0052 15.3 10.9 0.0072 14.8 7.6 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 AET41114.1 - 0.018 12.9 21.9 0.025 12.5 15.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AET41114.1 - 0.025 12.6 12.3 0.034 12.2 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 AET41114.1 - 0.48 10.2 18.3 0.86 9.4 12.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 AET41114.1 - 0.64 9.2 20.8 1.4 8.1 14.4 1.5 1 0 0 1 1 1 0 NOA36 protein VID27 PF08553.5 AET41114.1 - 1.1 7.4 10.4 1.5 6.9 7.2 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Cwf_Cwc_15 PF04889.7 AET41114.1 - 2.2 7.9 19.3 4 7.0 13.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 AET41114.1 - 7 5.9 15.4 13 5.0 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ETF_alpha PF00766.14 AET41115.1 - 8.8e-34 114.9 0.2 1.9e-33 113.9 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 AET41115.1 - 1.8e-28 99.3 0.1 3.3e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Transcrip_reg PF01709.15 AET41116.1 - 3.5e-74 248.8 1.5 4.1e-74 248.6 1.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator ATP-synt_F PF01990.12 AET41117.1 - 6.6e-31 106.5 0.2 7.6e-31 106.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 AET41117.1 - 0.013 14.8 0.1 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 DUF1882 PF08966.6 AET41117.1 - 0.041 13.8 0.2 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) BRCT PF00533.21 AET41118.1 - 1.7e-11 44.1 0.0 4.7e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AET41118.1 - 1.9e-05 24.4 0.0 4.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 AET41118.1 - 0.0002 21.4 0.0 0.00076 19.5 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain DUF3006 PF11213.3 AET41118.1 - 0.00055 19.6 4.3 0.0014 18.3 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3006) B12D PF06522.6 AET41119.1 - 0.015 14.9 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Mito_carr PF00153.22 AET41120.1 - 1.3e-71 236.3 3.2 5.7e-25 86.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Gtr1_RagA PF04670.7 AET41121.1 - 5.5e-68 228.5 0.2 7.5e-68 228.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 AET41121.1 - 0.0021 17.3 0.1 0.0067 15.6 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF2118 PF09891.4 AET41121.1 - 0.064 12.9 0.3 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) TYW3 PF02676.9 AET41122.1 - 7.8e-62 208.0 0.0 8.8e-62 207.8 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 Glyco_tran_28_C PF04101.11 AET41123.1 - 1.6e-23 83.2 0.0 4.3e-23 81.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 AET41123.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 E1-E2_ATPase PF00122.15 AET41124.1 - 1.6e-45 154.9 0.1 5.9e-45 153.0 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AET41124.1 - 2.3e-36 126.2 0.0 4.2e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AET41124.1 - 2.2e-19 70.3 0.0 5.7e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AET41124.1 - 1.8e-08 34.4 5.5 3.2e-05 23.9 0.3 4.7 4 0 0 4 4 4 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 AET41124.1 - 4.6e-05 23.1 0.4 0.074 12.6 0.1 2.6 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 AET41124.1 - 0.066 12.2 0.9 0.12 11.4 0.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein ELFV_dehydrog PF00208.16 AET41125.1 - 3.1e-59 200.4 0.0 5.8e-59 199.6 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 AET41125.1 - 2.8e-20 71.4 0.0 5e-13 47.4 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase NPR3 PF03666.8 AET41126.1 - 5.8e-156 519.5 1.3 7.6e-156 519.1 0.0 1.8 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 RRM_1 PF00076.17 AET41127.1 - 7.7e-31 105.5 4.1 2.2e-14 52.8 0.3 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET41127.1 - 6e-21 74.0 0.8 3.9e-08 33.0 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET41127.1 - 1.8e-20 72.6 0.2 3.3e-08 33.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AET41127.1 - 0.00068 19.3 0.1 3.5 7.4 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AET41127.1 - 0.00076 19.2 0.2 0.92 9.3 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif Myc_N PF01056.13 AET41127.1 - 0.00082 18.6 1.7 0.00082 18.6 1.2 2.3 2 0 0 2 2 2 1 Myc amino-terminal region Nup35_RRM PF05172.8 AET41127.1 - 0.0013 18.4 0.0 0.13 12.0 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Senescence_reg PF04520.8 AET41127.1 - 0.12 12.8 5.4 0.086 13.3 0.5 2.5 2 0 0 2 2 2 0 Senescence regulator Nucleoplasmin PF03066.10 AET41127.1 - 0.32 10.5 16.4 0.18 11.2 1.6 2.3 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 AET41127.1 - 9.8 6.4 21.8 3.3 7.9 4.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain AAA_2 PF07724.9 AET41128.1 - 1.1e-45 155.6 0.0 8.9e-45 152.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 AET41128.1 - 3.5e-23 81.3 0.3 1.5e-22 79.2 0.2 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 AET41128.1 - 8.7e-22 77.7 0.0 1.2e-12 48.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AET41128.1 - 1.9e-16 60.0 0.0 1.4e-09 37.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 AET41128.1 - 3.6e-13 49.2 1.2 5.5e-07 29.4 0.0 3.3 2 1 0 2 2 2 2 Clp amino terminal domain Sigma54_activat PF00158.21 AET41128.1 - 2.7e-12 46.4 0.0 3.6e-08 33.0 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 AET41128.1 - 4.1e-11 43.2 10.4 0.00016 21.7 0.0 5.0 4 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 AET41128.1 - 1.5e-10 41.2 0.2 0.00017 21.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 AET41128.1 - 6e-06 27.0 3.4 0.038 14.7 0.0 4.1 3 1 0 3 3 3 2 AAA domain TIP49 PF06068.8 AET41128.1 - 1.1e-05 24.4 0.8 0.49 9.0 0.0 3.9 4 0 0 4 4 4 2 TIP49 C-terminus AAA_3 PF07726.6 AET41128.1 - 0.00027 20.5 0.0 0.1 12.2 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AET41128.1 - 0.00027 20.0 0.2 0.0077 15.3 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.16 AET41128.1 - 0.00031 19.9 0.1 0.67 9.0 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AET41128.1 - 0.00098 19.4 0.1 0.25 11.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AET41128.1 - 0.0015 18.2 1.1 1.1 8.8 0.0 3.9 3 1 1 4 4 4 1 Archaeal ATPase NACHT PF05729.7 AET41128.1 - 0.0018 17.9 0.0 0.52 9.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 AET41128.1 - 0.0028 17.5 0.0 0.16 11.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain Torsin PF06309.6 AET41128.1 - 0.0052 16.6 0.0 0.027 14.3 0.0 2.3 2 0 0 2 2 1 1 Torsin Glyco_hydro_47 PF01532.15 AET41128.1 - 0.0078 14.9 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IstB_IS21 PF01695.12 AET41128.1 - 0.016 14.6 0.0 1.3 8.3 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.1 AET41128.1 - 0.018 14.8 0.0 0.57 9.9 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Viral_helicase1 PF01443.13 AET41128.1 - 0.024 14.1 0.0 1.2 8.6 0.0 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.15 AET41128.1 - 0.034 13.8 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 1 0 Adenylylsulphate kinase PEPCK_ATP PF01293.15 AET41128.1 - 0.074 11.5 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase MobB PF03205.9 AET41128.1 - 0.079 12.6 0.0 8.4 6.1 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 AET41128.1 - 0.08 12.5 0.0 5.7 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AET41128.1 - 0.1 12.7 0.2 17 5.6 0.0 3.0 3 0 0 3 3 3 0 RNA helicase APG6 PF04111.7 AET41128.1 - 1.6 7.6 10.3 3 6.7 7.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 AET41128.1 - 2.6 7.5 17.3 1.3 8.5 10.2 1.8 2 0 0 2 2 1 0 IncA protein V_ATPase_I PF01496.14 AET41128.1 - 2.9 5.6 7.3 4.3 5.0 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sod_Cu PF00080.15 AET41129.1 - 1.9e-15 57.2 0.0 4.4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MIP-T3 PF10243.4 AET41129.1 - 5.2 5.4 20.3 6.5 5.1 14.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Fe-S_biosyn PF01521.15 AET41130.1 - 8.3e-18 64.3 0.0 1.9e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.2 AET41130.1 - 0.022 14.5 0.2 0.096 12.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3853) Peptidase_M24 PF00557.19 AET41131.1 - 3.4e-39 134.5 0.0 5.6e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 AET41131.1 - 2e-12 47.7 0.0 6.5e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Cofilin_ADF PF00241.15 AET41132.1 - 1.7e-06 27.9 0.0 2.6e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ribosomal_S13_N PF08069.7 AET41133.1 - 8.3e-25 86.4 0.7 1.2e-24 85.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AET41133.1 - 3.3e-22 78.0 0.1 1.4e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 MFS_1 PF07690.11 AET41137.1 - 1.8e-31 109.1 21.2 2.6e-31 108.6 14.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily WW PF00397.21 AET41138.1 - 5.9e-06 26.0 0.6 1.2e-05 25.0 0.4 1.6 1 0 0 1 1 1 1 WW domain Gly-zipper_OmpA PF13436.1 AET41138.1 - 0.0033 17.0 0.5 0.0033 17.0 0.3 1.9 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain DUF605 PF04652.11 AET41138.1 - 0.047 13.0 3.5 0.053 12.9 2.4 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 AET41138.1 - 4.2 5.4 14.7 4.7 5.3 10.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 AET41139.1 - 9.3e-49 161.6 11.1 6.7e-11 41.6 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 AET41139.1 - 5.9e-08 32.3 0.1 1.3e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AET41139.1 - 2.3e-07 30.3 1.8 4e-07 29.5 0.3 2.1 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 AET41139.1 - 0.0098 14.0 4.8 0.19 9.8 0.1 3.9 3 2 0 3 3 3 1 Nucleoporin Nup120/160 PRANC PF09372.5 AET41139.1 - 0.02 14.8 0.1 0.02 14.8 0.1 2.3 3 0 0 3 3 3 0 PRANC domain Virul_fac_BrkB PF03631.10 AET41140.1 - 0.064 12.6 7.9 0.084 12.2 5.5 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF788 PF05620.6 AET41140.1 - 0.15 11.8 0.9 0.25 11.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF2207 PF09972.4 AET41140.1 - 0.21 10.1 1.2 0.24 9.9 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SMC_N PF02463.14 AET41141.1 - 1.4e-54 184.6 33.6 5.2e-54 182.7 23.3 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AET41141.1 - 6.6e-27 93.8 0.2 3e-26 91.7 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AET41141.1 - 1.2e-10 41.8 10.0 1.5e-06 28.3 0.5 4.5 2 2 3 5 5 5 2 AAA domain AAA_29 PF13555.1 AET41141.1 - 4.1e-08 32.6 0.1 8.5e-08 31.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 AET41141.1 - 0.00019 20.0 12.1 0.00019 20.0 8.4 5.8 3 2 3 6 6 5 2 AAA domain CENP-F_leu_zip PF10473.4 AET41141.1 - 0.0052 16.6 28.8 0.0052 16.6 20.0 8.7 3 3 3 7 7 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SNARE PF05739.14 AET41141.1 - 0.0054 16.3 0.7 0.0054 16.3 0.5 5.8 5 1 1 6 6 6 1 SNARE domain DUF3407 PF11887.3 AET41141.1 - 0.019 14.2 0.9 0.49 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) SbcCD_C PF13558.1 AET41141.1 - 0.028 14.3 0.0 0.099 12.5 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 AET41141.1 - 0.057 13.7 0.0 0.057 13.7 0.0 6.1 4 3 0 4 4 2 0 ABC transporter Reo_sigmaC PF04582.7 AET41141.1 - 0.091 11.9 31.0 0.013 14.7 2.2 4.8 3 1 2 5 5 5 0 Reovirus sigma C capsid protein AAA_17 PF13207.1 AET41141.1 - 0.77 10.5 0.0 0.77 10.5 0.0 3.7 3 3 0 4 4 4 0 AAA domain DASH_Dam1 PF08653.5 AET41141.1 - 8.4 6.2 9.8 1.5 8.6 0.0 4.3 4 0 0 4 4 3 0 DASH complex subunit Dam1 Ras PF00071.17 AET41142.1 - 7.4e-64 214.0 0.5 8.6e-64 213.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AET41142.1 - 1.8e-20 73.6 0.1 2.5e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AET41142.1 - 2.5e-18 65.9 0.1 3.1e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET41142.1 - 5e-08 32.3 0.1 6.4e-08 32.0 0.1 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AET41142.1 - 7.1e-07 28.6 0.1 8.7e-07 28.3 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 AET41142.1 - 2.3e-06 27.1 0.2 1.5e-05 24.5 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AET41142.1 - 3.4e-06 27.0 0.1 4.7e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AET41142.1 - 0.0015 17.8 0.1 0.018 14.3 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 AET41142.1 - 0.0059 16.7 0.0 0.045 13.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain MCM PF00493.18 AET41142.1 - 0.0092 14.8 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family DUF258 PF03193.11 AET41142.1 - 0.0099 15.0 0.0 0.016 14.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 G-alpha PF00503.15 AET41142.1 - 0.014 14.1 1.0 2.3 6.8 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 AET41142.1 - 0.016 15.2 0.3 0.034 14.1 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 AET41142.1 - 0.019 14.4 0.2 0.065 12.7 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 AET41142.1 - 0.025 14.7 0.0 0.64 10.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 AET41142.1 - 0.067 12.1 0.0 0.16 10.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 AET41142.1 - 0.076 13.3 0.2 0.26 11.6 0.1 2.0 1 1 0 1 1 1 0 ABC transporter VTC PF09359.5 AET41143.1 - 1.4e-90 303.1 0.0 2.1e-90 302.5 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 AET41143.1 - 7.7e-25 88.2 16.4 1e-15 58.2 3.6 3.5 2 1 0 3 3 3 2 SPX domain DUF202 PF02656.10 AET41143.1 - 3e-09 36.9 4.5 3e-09 36.9 3.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MtrG PF04210.8 AET41143.1 - 0.15 11.7 1.7 0.32 10.6 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Peptidase_C48 PF02902.14 AET41144.1 - 2e-36 125.6 0.8 4.8e-36 124.4 0.5 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Antistasin PF02822.9 AET41144.1 - 0.21 11.9 1.1 0.52 10.6 0.8 1.7 1 0 0 1 1 1 0 Antistasin family MutS_V PF00488.16 AET41145.1 - 6e-69 232.0 0.3 1.3e-68 230.9 0.2 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AET41145.1 - 9.2e-33 113.7 0.1 2.6e-32 112.2 0.0 1.8 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.12 AET41145.1 - 3.3e-15 56.3 0.1 1.1e-14 54.6 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 AET41145.1 - 6.7e-15 55.0 0.4 8.3e-14 51.5 0.1 2.8 2 0 0 2 2 2 1 MutS family domain IV Epsilon_antitox PF08998.6 AET41145.1 - 0.088 12.7 3.5 0.14 12.1 0.1 2.9 2 0 0 2 2 2 0 Bacterial epsilon antitoxin SIR2 PF02146.12 AET41146.1 - 8.6e-50 168.9 0.0 1.3e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Clat_adaptor_s PF01217.15 AET41147.1 - 3.6e-17 62.3 0.7 4.8e-17 61.9 0.5 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Bromo_TP PF07524.8 AET41148.1 - 1e-05 25.1 0.0 2.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated NUC173 PF08161.7 AET41149.1 - 9.3e-75 250.3 0.1 1.3e-72 243.3 0.1 3.4 3 0 0 3 3 3 1 NUC173 domain UME PF08064.8 AET41149.1 - 9.9e-05 22.2 6.0 0.16 11.9 0.2 4.6 3 0 0 3 3 3 2 UME (NUC010) domain HEAT PF02985.17 AET41149.1 - 0.014 15.4 2.9 8.8 6.7 0.0 4.9 6 0 0 6 6 6 0 HEAT repeat Ribosomal_S16 PF00886.14 AET41150.1 - 3.9e-25 87.3 0.1 5.5e-25 86.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 PDR_assoc PF08370.6 AET41150.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Cortexin PF11057.3 AET41152.1 - 0.026 14.0 2.5 1.1 8.8 0.4 2.5 2 0 0 2 2 2 0 Cortexin of kidney VirB3 PF05101.8 AET41152.1 - 1.6 8.7 9.2 0.44 10.5 0.7 2.7 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein zf-TFIIIC PF12660.2 AET41153.1 - 1.1e-09 38.0 0.0 2.9e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Patched PF02460.13 AET41154.1 - 8.5e-57 192.6 22.1 1.5e-33 115.7 0.7 2.3 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 AET41154.1 - 3.2e-38 130.5 8.1 3.2e-38 130.5 5.6 3.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation PPR_2 PF13041.1 AET41155.1 - 1.6e-15 56.8 5.9 4e-07 29.9 0.3 4.0 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 AET41155.1 - 1.3e-10 40.7 0.0 0.035 14.3 0.0 5.0 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 AET41155.1 - 0.0078 15.6 0.2 2.8 7.5 0.0 3.2 3 1 0 3 3 3 1 PPR repeat Glyphos_transf PF04464.9 AET41155.1 - 0.0087 14.8 1.5 0.0087 14.8 1.0 1.8 2 0 0 2 2 2 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase PPR PF01535.15 AET41155.1 - 0.028 14.3 7.5 1.5 8.9 0.0 5.3 5 0 0 5 5 5 0 PPR repeat ECSIT PF06239.6 AET41155.1 - 0.043 12.6 0.3 3.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Pil1 PF13805.1 AET41156.1 - 2.5e-150 499.1 0.1 3e-150 498.8 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.5 AET41156.1 - 0.28 11.0 0.2 0.28 11.0 0.1 3.0 4 0 0 4 4 4 0 Proto-chlorophyllide reductase 57 kD subunit DEAD PF00270.24 AET41158.1 - 8.6e-40 135.9 0.1 2.7e-39 134.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET41158.1 - 4.8e-21 74.4 0.0 2.1e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AET41158.1 - 2.4e-14 52.5 0.0 5.1e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AET41158.1 - 0.0075 16.1 5.5 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PseudoU_synth_1 PF01416.15 AET41159.1 - 8.6e-29 100.0 0.0 2.3e-18 66.5 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2312 PF10073.4 AET41159.1 - 0.11 11.8 2.0 0.71 9.2 1.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) EAP30 PF04157.11 AET41160.1 - 2.6e-52 177.2 0.0 2.8e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Hat1_N PF10394.4 AET41161.1 - 2.6e-37 128.3 1.1 2.6e-37 128.3 0.7 2.1 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 AET41161.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AET41161.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AET41161.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF3618 PF12277.3 AET41162.1 - 0.0066 16.4 1.2 0.017 15.1 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) Tox-ODYAM1 PF15642.1 AET41162.1 - 0.1 11.2 11.8 0.12 10.9 8.2 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Not1 PF04054.10 AET41162.1 - 0.14 11.0 3.9 0.047 12.5 0.9 1.5 1 1 1 2 2 2 0 CCR4-Not complex component, Not1 MmgE_PrpD PF03972.9 AET41163.1 - 6.6e-154 512.3 0.0 8.3e-154 512.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PPI_Ypi1 PF07491.6 AET41164.1 - 1.9e-24 85.0 3.9 3.6e-24 84.1 2.7 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor SYF2 PF08231.7 AET41164.1 - 0.066 13.3 7.8 0.64 10.1 1.3 2.1 1 1 1 2 2 2 0 SYF2 splicing factor Staphylcoagulse PF04022.7 AET41164.1 - 0.083 12.2 0.1 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 Staphylocoagulase repeat YolD PF08863.5 AET41164.1 - 0.094 12.5 0.5 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 YolD-like protein SR-25 PF10500.4 AET41164.1 - 0.6 9.5 10.6 0.63 9.4 6.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 AET41164.1 - 1.1 7.1 6.9 1.3 6.9 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein JAB PF01398.16 AET41165.1 - 1.4e-33 114.9 0.2 1.4e-33 114.9 0.1 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 AET41165.1 - 1.3e-24 86.5 4.9 1.3e-24 86.5 3.4 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 AET41165.1 - 8.9e-09 34.8 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 AET41165.1 - 0.034 13.6 0.7 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) UCH PF00443.24 AET41166.1 - 1.2e-19 70.5 1.9 2.1e-19 69.6 1.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AET41166.1 - 2.5e-10 40.3 0.0 5.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_M24 PF00557.19 AET41167.1 - 4.4e-60 202.8 0.0 5.9e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AET41167.1 - 8.9e-24 83.3 0.0 3.8e-23 81.3 0.0 2.1 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain PITH PF06201.8 AET41168.1 - 7e-40 136.2 0.3 9e-40 135.9 0.2 1.1 1 0 0 1 1 1 1 PITH domain ALAD PF00490.16 AET41169.1 - 6.5e-112 373.6 0.0 7.9e-112 373.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Snf7 PF03357.16 AET41170.1 - 5.7e-34 116.9 6.8 7.3e-34 116.6 4.7 1.1 1 0 0 1 1 1 1 Snf7 Lon_2 PF13337.1 AET41170.1 - 0.042 12.2 2.1 0.078 11.3 0.1 1.9 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease DUF2521 PF10730.4 AET41170.1 - 2.6 7.8 6.7 0.77 9.5 2.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2521) PALP PF00291.20 AET41171.1 - 3.6e-59 200.4 0.0 4.7e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 AET41171.1 - 1.9e-14 53.1 0.2 1.4e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain GHMP_kinases_C PF08544.8 AET41171.1 - 0.032 14.4 0.1 0.97 9.6 0.0 2.6 3 0 0 3 3 3 0 GHMP kinases C terminal ComZ PF10815.3 AET41172.1 - 0.0015 18.2 0.2 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 ComZ YicC_N PF03755.8 AET41172.1 - 0.028 14.3 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 YicC-like family, N-terminal region TFIIS_M PF07500.9 AET41173.1 - 4.7e-31 107.2 1.6 9.5e-31 106.2 0.1 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 AET41173.1 - 1.1e-17 63.3 6.6 2.3e-17 62.3 4.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 AET41173.1 - 8.2e-15 54.0 2.4 1.9e-14 52.8 1.6 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SR-25 PF10500.4 AET41173.1 - 0.0093 15.4 2.3 0.016 14.7 1.6 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Phyto_Pns9_10 PF05878.6 AET41173.1 - 0.068 12.1 3.8 0.088 11.7 2.6 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Gly_radical PF01228.16 AET41173.1 - 0.3 11.4 2.2 0.94 9.8 0.0 2.4 2 1 1 3 3 3 0 Glycine radical Ribosomal_S27 PF01599.14 AET41173.1 - 0.94 9.3 4.3 2.4 8.0 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein S27a RRM_1 PF00076.17 AET41174.1 - 1.3e-19 69.5 0.0 2.2e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET41174.1 - 9.7e-15 54.3 0.0 1.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET41174.1 - 5.3e-10 38.9 0.0 8.9e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 AET41174.1 - 1.5e-08 33.7 0.1 4.7e-08 32.1 0.1 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.1 AET41174.1 - 1e-06 28.6 1.3 2.2e-06 27.6 0.9 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF2_hinge PF14327.1 AET41175.1 - 1.4e-23 82.7 2.6 2e-22 79.0 2.1 2.5 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 AET41175.1 - 0.00031 19.9 1.6 0.00087 18.5 1.1 1.7 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal PAT1 PF09770.4 AET41175.1 - 5.4 5.1 18.0 6.7 4.8 12.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cytochrom_B_C PF00032.12 AET41177.1 - 1.7 8.9 7.0 1.2 9.3 2.1 2.1 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD PWI PF01480.12 AET41179.1 - 0.00027 20.9 1.0 0.00082 19.4 0.1 2.2 2 0 0 2 2 2 1 PWI domain PALP PF00291.20 AET41180.1 - 9.9e-60 202.3 0.3 1.2e-59 202.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.16 AET41180.1 - 0.0046 16.5 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CTP_transf_2 PF01467.21 AET41181.1 - 9.9e-34 116.6 0.0 1.4e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase RCC1 PF00415.13 AET41182.1 - 1.2e-22 79.8 14.5 0.00015 21.9 0.0 7.2 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AET41182.1 - 1.9e-16 59.2 25.0 2.1e-07 30.3 0.4 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat TES PF08034.6 AET41182.1 - 0.028 14.5 0.7 0.12 12.4 0.1 2.3 3 0 0 3 3 3 0 Trematode eggshell synthesis protein Exo_endo_phos PF03372.18 AET41183.1 - 1.3e-24 87.4 0.0 1.9e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 AET41183.1 - 1.2e-18 66.2 7.7 7.2e-11 41.4 1.5 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AET41183.1 - 1.7e-18 66.1 15.4 8.7e-10 38.2 0.3 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AET41183.1 - 1.2e-08 33.8 10.5 0.013 15.4 0.1 5.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 AET41183.1 - 1.3e-07 30.5 7.1 0.0057 16.6 0.1 4.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 AET41183.1 - 0.074 13.1 5.1 3.8 7.8 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat PMT PF02366.13 AET41184.1 - 2.9e-91 305.1 15.4 2.9e-91 305.1 10.7 2.9 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AET41184.1 - 6.5e-27 94.2 3.1 1.6e-26 92.9 2.1 1.6 1 1 0 1 1 1 1 MIR domain DUF4491 PF14898.1 AET41184.1 - 4.4 7.5 12.9 0.49 10.5 2.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) LDB19 PF13002.2 AET41185.1 - 1.4e-70 236.7 0.0 2.1e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like RasGEF PF00617.14 AET41186.1 - 6.6e-42 143.3 6.0 7e-42 143.2 2.6 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 AET41186.1 - 3e-15 56.2 0.6 1.7e-14 53.7 0.2 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif SPRY PF00622.23 AET41187.1 - 1.7e-05 24.9 0.1 0.0041 17.1 0.0 2.6 2 1 0 2 2 2 2 SPRY domain Pkinase PF00069.20 AET41188.1 - 1.6e-68 230.7 0.0 2.2e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41188.1 - 2.1e-31 108.9 0.0 3.4e-31 108.2 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 AET41188.1 - 0.0039 16.2 0.0 0.0064 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET41188.1 - 0.027 14.2 0.1 0.089 12.5 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family PIF1 PF05970.9 AET41189.1 - 1.4e-54 185.4 0.1 8.3e-52 176.3 0.1 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 AET41189.1 - 6.2e-19 68.3 0.0 1.7e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AET41189.1 - 8.1e-06 26.0 0.0 7e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 AET41189.1 - 1.8e-05 22.7 0.0 5.9e-05 21.0 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA PF00004.24 AET41189.1 - 0.00063 19.9 0.1 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AET41189.1 - 0.0014 18.6 0.3 0.012 15.5 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 AET41189.1 - 0.0047 16.6 0.6 0.038 13.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 AET41189.1 - 0.013 15.0 0.4 4.4 6.7 0.2 2.9 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 AET41189.1 - 0.028 13.0 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.11 AET41189.1 - 0.029 13.5 0.1 0.078 12.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.1 AET41189.1 - 0.033 14.3 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 AET41189.1 - 0.036 13.0 0.3 0.19 10.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 AET41189.1 - 0.042 12.7 0.1 0.07 12.0 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 AET41189.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 AET41189.1 - 0.05 13.3 0.9 0.11 12.2 0.6 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 AET41189.1 - 0.054 14.3 0.0 0.2 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AET41189.1 - 0.11 12.7 0.0 0.52 10.5 0.0 2.1 1 1 0 1 1 1 0 RNA helicase Helicase_RecD PF05127.9 AET41189.1 - 0.14 11.7 1.0 1.1 8.8 0.7 2.1 1 1 0 1 1 1 0 Helicase GCR1_C PF12550.3 AET41190.1 - 3.7e-14 52.3 0.8 6.8e-14 51.5 0.5 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Zip PF02535.17 AET41190.1 - 0.016 14.1 3.5 0.019 14.0 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF73-100_C PF11718.3 AET41190.1 - 0.15 11.3 3.3 0.26 10.6 1.6 1.9 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF4588 PF15251.1 AET41190.1 - 1.5 8.7 7.5 3.3 7.6 5.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4588) Ribosomal_L1 PF00687.16 AET41191.1 - 1.5e-40 138.8 4.0 2.9e-40 137.9 2.8 1.6 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF4263 PF14082.1 AET41191.1 - 0.069 13.0 2.3 0.068 13.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) Elf1 PF05129.8 AET41192.1 - 4.3e-30 103.2 3.2 5.7e-30 102.8 2.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.14 AET41192.1 - 0.029 14.2 1.2 0.053 13.3 0.8 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF4578 PF15147.1 AET41192.1 - 0.061 13.6 0.7 0.097 13.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) zf-C2H2_2 PF12756.2 AET41192.1 - 0.17 12.0 3.2 2.6 8.2 0.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 AET41192.1 - 0.22 11.5 0.4 0.22 11.5 0.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4611 PF15387.1 AET41192.1 - 0.77 9.9 8.8 2.2 8.4 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) COX5A PF02284.11 AET41193.1 - 2.6e-49 165.6 1.4 3.3e-49 165.3 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF488 PF04343.8 AET41193.1 - 0.018 15.3 0.3 0.08 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF488 GerPC PF10737.4 AET41193.1 - 0.031 14.0 0.2 0.69 9.6 0.0 2.0 2 0 0 2 2 2 0 Spore germination protein GerPC DUF4286 PF14114.1 AET41193.1 - 0.041 14.1 0.3 5 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Calcipressin PF04847.7 AET41194.1 - 1.7e-12 47.2 0.2 2.4e-12 46.8 0.2 1.3 1 1 0 1 1 1 1 Calcipressin SUI1 PF01253.17 AET41195.1 - 3.3e-20 71.6 2.2 6.3e-20 70.7 1.5 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 OmpH PF03938.9 AET41195.1 - 0.035 14.0 3.8 0.062 13.2 2.6 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF947 PF06102.7 AET41195.1 - 1.9 8.3 12.3 0.079 12.7 4.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF947) TPR_11 PF13414.1 AET41196.1 - 0.0062 16.1 0.0 4.1 7.1 0.0 3.9 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.1 AET41196.1 - 0.0068 16.5 0.7 1.5 9.1 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AET41196.1 - 0.015 15.9 0.0 10 6.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat YppF PF14178.1 AET41196.1 - 0.03 13.8 0.6 0.38 10.3 0.1 2.7 3 0 0 3 3 3 0 YppF-like protein TPR_14 PF13428.1 AET41196.1 - 0.061 13.9 0.0 22 6.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Lipase_3 PF01764.20 AET41197.1 - 3.3e-30 104.5 0.0 4.7e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 AET41197.1 - 0.16 12.1 0.1 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PMT PF02366.13 AET41198.1 - 6.3e-62 209.1 14.2 6.3e-62 209.1 9.8 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AET41198.1 - 6.9e-11 42.0 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 AET41198.1 - 9.3e-06 25.6 12.1 9.3e-06 25.6 8.4 3.7 3 2 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.27 AET41199.1 - 8.6e-52 171.2 21.6 1.5e-09 37.3 0.0 10.8 12 0 0 12 12 12 8 WD domain, G-beta repeat BBS2_Mid PF14783.1 AET41199.1 - 2.2e-05 24.2 0.0 0.0011 18.7 0.0 3.6 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region ILVD_EDD PF00920.16 AET41200.1 - 4.3e-204 678.7 0.0 4.9e-204 678.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family CTP_transf_2 PF01467.21 AET41201.1 - 5.3e-25 88.3 0.0 8.6e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Rhodanese PF00581.15 AET41202.1 - 4.3e-12 46.3 0.0 6.1e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Rotamase PF00639.16 AET41203.1 - 1.6e-25 89.6 0.0 2.3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 AET41203.1 - 2.8e-19 69.4 0.0 3.9e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 AET41203.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 AET41203.1 - 2.3e-07 31.4 0.0 4.9e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain RNaseH_C PF09293.5 AET41203.1 - 0.0057 16.5 0.1 0.031 14.1 0.1 1.9 1 1 1 2 2 2 1 T4 RNase H, C terminal FTHFS PF01268.14 AET41204.1 - 1.8e-250 831.6 0.5 2.3e-250 831.3 0.3 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 AET41204.1 - 1.7e-60 202.7 0.3 5.3e-60 201.1 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AET41204.1 - 4.5e-36 123.4 0.1 1.2e-35 122.0 0.1 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 AET41204.1 - 0.011 15.6 2.9 1.5 8.6 0.2 3.2 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acyl_CoA_thio PF02551.10 AET41205.1 - 5.3e-22 77.8 0.2 2.7e-14 52.9 0.1 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 AET41205.1 - 9.9e-18 64.7 0.0 2.3e-17 63.6 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily AAA_17 PF13207.1 AET41206.1 - 1.9e-05 25.5 0.0 3.3e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AET41206.1 - 0.00055 19.0 0.0 0.00086 18.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 AET41206.1 - 0.00079 19.4 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.17 AET41206.1 - 0.0032 16.9 0.0 0.0075 15.7 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 AET41206.1 - 0.0067 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 AET41206.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AET41206.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AET41206.1 - 0.021 14.9 0.0 0.07 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AET41206.1 - 0.028 14.7 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AET41206.1 - 0.033 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AET41206.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AET41206.1 - 0.12 12.3 0.0 3.9 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mer2 PF09074.5 AET41207.1 - 8.8e-34 117.0 11.5 1.7e-33 116.1 8.0 1.4 1 1 0 1 1 1 1 Mer2 Phage_min_cap2 PF06152.6 AET41207.1 - 0.02 13.9 5.3 0.023 13.6 3.7 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 ApoLp-III PF07464.6 AET41207.1 - 0.094 12.7 9.9 0.67 9.9 2.0 2.5 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3206 PF11472.3 AET41207.1 - 0.12 12.1 1.1 0.27 11.0 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3206) TraV PF09676.5 AET41207.1 - 0.46 11.1 3.7 0.33 11.6 0.9 1.9 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Occludin_ELL PF07303.8 AET41207.1 - 1 10.1 5.3 0.59 10.8 0.5 2.2 2 0 0 2 2 2 0 Occludin homology domain Nsp1_C PF05064.8 AET41207.1 - 1.4 8.5 13.6 0.087 12.4 1.4 3.0 3 1 0 3 3 3 0 Nsp1-like C-terminal region Rab5-bind PF09311.6 AET41207.1 - 2.2 8.1 12.0 0.41 10.5 1.8 2.1 2 0 0 2 2 2 0 Rabaptin-like protein DUF2203 PF09969.4 AET41207.1 - 2.5 8.3 5.2 2.1 8.5 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CENP-F_leu_zip PF10473.4 AET41207.1 - 2.9 7.7 14.6 2.9 7.7 3.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DNA_repr_REX1B PF14966.1 AET41207.1 - 6.7 7.1 10.2 1.1 9.6 2.8 2.4 2 2 0 2 2 2 0 DNA repair REX1-B LSM PF01423.17 AET41208.1 - 1.2e-12 47.1 0.1 2.5e-12 46.1 0.0 1.5 2 0 0 2 2 2 1 LSM domain Viral_Rep PF02407.11 AET41208.1 - 0.002 18.0 0.3 0.0034 17.3 0.1 1.5 1 1 1 2 2 2 1 Putative viral replication protein Aldolase_II PF00596.16 AET41209.1 - 1.9e-41 141.7 0.0 2.3e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF4194 PF13835.1 AET41209.1 - 0.077 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) 3-HAO PF06052.7 AET41210.1 - 5.1e-65 217.4 0.0 5.9e-65 217.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 AET41210.1 - 3.2e-06 26.5 0.0 4.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 AET41210.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Cupin Nudix_N_2 PF14803.1 AET41210.1 - 0.022 14.4 1.8 4.3 7.1 0.3 2.6 2 0 0 2 2 2 0 Nudix N-terminal zf-B_box PF00643.19 AET41210.1 - 0.026 14.4 4.2 0.028 14.3 0.6 2.2 2 0 0 2 2 2 0 B-box zinc finger zf-C2H2_3 PF13878.1 AET41210.1 - 0.51 9.9 0.1 0.51 9.9 0.0 2.3 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO ADK_lid PF05191.9 AET41210.1 - 2.3 7.9 5.7 4.6 6.9 0.1 2.7 4 0 0 4 4 4 0 Adenylate kinase, active site lid Mvb12 PF09452.5 AET41211.1 - 2.1e-27 95.0 0.1 2.4e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 ETF PF01012.16 AET41212.1 - 5.1e-32 110.8 0.2 6.4e-32 110.5 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain HAD PF12710.2 AET41213.1 - 7.9e-14 52.2 0.1 1.2e-13 51.7 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AET41213.1 - 2.5e-13 50.9 0.6 5.8e-12 46.4 0.2 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AET41213.1 - 1.2e-10 41.4 0.3 3.6e-09 36.5 0.0 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 AET41213.1 - 4e-05 22.9 0.0 7.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Putative Phosphatase S6PP PF05116.8 AET41213.1 - 0.00058 19.2 0.0 0.0095 15.2 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.1 AET41213.1 - 0.0073 16.5 0.1 0.18 12.0 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 AET41213.1 - 0.048 12.6 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Acid_PPase PF12689.2 AET41213.1 - 0.086 12.4 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 Acid Phosphatase Thioredoxin PF00085.15 AET41214.1 - 1.1e-29 102.1 0.3 1.3e-29 101.9 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AET41214.1 - 1.3e-07 31.5 0.1 5e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AET41214.1 - 8.5e-07 29.1 0.3 2.2e-05 24.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 AET41214.1 - 3.6e-05 23.4 0.1 4.1e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AET41214.1 - 7.8e-05 22.2 0.0 8.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 AET41214.1 - 0.00047 19.7 0.1 0.00053 19.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 AET41214.1 - 0.00068 19.6 0.1 0.001 19.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.11 AET41214.1 - 0.005 15.5 0.1 0.0057 15.4 0.0 1.0 1 0 0 1 1 1 1 Phosducin DIM1 PF02966.11 AET41214.1 - 0.0076 15.7 0.2 0.0085 15.6 0.1 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_4 PF13462.1 AET41214.1 - 0.036 14.0 0.3 0.059 13.3 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.19 AET41214.1 - 0.041 13.8 0.1 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF1351 PF07083.6 AET41214.1 - 0.051 13.1 0.1 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) TraF PF13728.1 AET41214.1 - 0.13 11.6 0.1 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Sigma54_activ_2 PF14532.1 AET41215.1 - 0.019 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Utp11 PF03998.8 AET41216.1 - 3.7e-72 243.0 25.7 4.2e-72 242.8 17.8 1.0 1 0 0 1 1 1 1 Utp11 protein PAS_10 PF13596.1 AET41216.1 - 0.014 15.6 0.7 0.014 15.6 0.5 2.6 2 1 0 2 2 2 0 PAS domain ADH_N PF08240.7 AET41217.1 - 1.1e-30 105.5 0.6 2.5e-30 104.4 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AET41217.1 - 4e-27 94.3 0.6 5.9e-27 93.7 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AET41217.1 - 4.1e-05 24.4 0.1 0.00012 22.9 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.20 AET41218.1 - 1.9e-75 253.3 0.0 3.8e-75 252.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41218.1 - 3.5e-39 134.4 0.4 7.4e-39 133.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Mrr_N PF14338.1 AET41218.1 - 0.0038 17.2 0.1 0.076 13.1 0.0 3.1 3 0 0 3 3 3 1 Mrr N-terminal domain APH PF01636.18 AET41218.1 - 0.0078 15.9 0.0 0.064 12.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AET41218.1 - 0.013 14.5 0.0 0.032 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AET41218.1 - 0.016 14.2 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Peptidase_M18 PF02127.10 AET41219.1 - 2.5e-135 451.3 0.0 2.9e-135 451.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) SIS PF01380.17 AET41221.1 - 9e-58 193.5 0.1 9.6e-31 106.1 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 AET41221.1 - 1.2e-30 106.4 0.0 3.9e-22 78.4 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AET41221.1 - 3.3e-18 65.9 0.0 7.2e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AET41221.1 - 3.5e-12 46.1 0.0 7.6e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 AET41221.1 - 2.8e-10 39.3 0.1 5e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Aminotran_1_2 PF00155.16 AET41223.1 - 2.8e-75 253.5 0.0 3.2e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Macro_2 PF14519.1 AET41224.1 - 2e-67 227.2 0.0 2.4e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.16 AET41224.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Macro domain MFS_1 PF07690.11 AET41225.1 - 3.7e-36 124.5 31.6 1.6e-35 122.5 21.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AET41225.1 - 2.4e-12 46.1 6.1 2.4e-12 46.1 4.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter DUF4564 PF15169.1 AET41225.1 - 0.3 10.7 2.5 2.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4564) Peptidase_M41 PF01434.13 AET41226.1 - 6.2e-72 241.5 0.1 1.2e-71 240.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AET41226.1 - 1.7e-42 144.7 0.0 4.9e-42 143.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 AET41226.1 - 7e-07 29.3 0.2 2.2e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 AET41226.1 - 8.2e-05 23.4 0.1 0.00057 20.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AET41226.1 - 0.00057 19.6 0.1 0.0036 17.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AET41226.1 - 0.0023 18.0 0.0 0.16 12.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 AET41226.1 - 0.0027 16.5 0.0 0.0049 15.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 AET41226.1 - 0.0073 15.3 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AET41226.1 - 0.0086 15.8 1.2 0.022 14.4 0.8 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 AET41226.1 - 0.01 15.7 1.1 0.027 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Fe-ADH_2 PF13685.1 AET41226.1 - 0.014 14.7 0.1 0.16 11.2 0.0 2.7 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase IstB_IS21 PF01695.12 AET41226.1 - 0.018 14.4 0.0 0.047 13.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 AET41226.1 - 0.047 13.6 2.6 0.072 13.0 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 AET41226.1 - 0.064 13.1 0.5 0.36 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AET41226.1 - 0.07 12.5 1.1 0.21 10.9 0.4 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 AET41226.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.1 AET41226.1 - 1.4 8.4 9.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain CRC_subunit PF08624.5 AET41227.1 - 9.2e-57 190.8 0.0 1.6e-56 190.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Nop14 PF04147.7 AET41227.1 - 0.0077 14.2 19.0 0.01 13.8 13.2 1.1 1 0 0 1 1 1 1 Nop14-like family TFIIF_alpha PF05793.7 AET41227.1 - 2.3 6.5 21.3 3.1 6.0 14.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 AET41227.1 - 2.7 7.2 15.4 4.2 6.6 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ebola_NP PF05505.7 AET41227.1 - 4 5.3 11.7 5.6 4.8 8.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Daxx PF03344.10 AET41227.1 - 6.8 5.0 25.6 9.5 4.5 17.8 1.1 1 0 0 1 1 1 0 Daxx Family WD40 PF00400.27 AET41228.1 - 6.3e-28 95.6 29.5 4.7e-05 23.0 0.3 11.3 11 1 0 11 11 11 8 WD domain, G-beta repeat PQQ_2 PF13360.1 AET41228.1 - 6.1e-05 22.5 1.8 0.022 14.2 1.2 2.7 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 AET41228.1 - 0.0099 14.0 1.1 0.11 10.5 0.0 2.4 2 1 0 2 2 2 1 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.1 AET41228.1 - 0.018 14.0 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus UTP15_C PF09384.5 AET41229.1 - 2.8e-52 176.3 0.1 4.3e-52 175.7 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 AET41229.1 - 6.1e-18 63.9 8.5 8.1e-07 28.6 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 AET41229.1 - 0.075 12.8 0.0 4.1 7.2 0.0 3.5 2 2 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Drc1-Sld2 PF11719.3 AET41230.1 - 2.9e-51 174.9 33.0 3.3e-49 168.1 22.9 2.6 1 1 0 1 1 1 1 DNA replication and checkpoint protein MbeB_N PF04837.7 AET41230.1 - 0.034 14.2 0.4 1.9 8.6 0.0 3.1 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Hap4_Hap_bind PF10297.4 AET41232.1 - 9.7e-09 34.7 8.5 1.8e-08 33.9 5.9 1.5 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Herpes_BLRF2 PF05812.7 AET41232.1 - 0.0063 16.3 0.3 0.013 15.2 0.2 1.5 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein CENP-H PF05837.7 AET41232.1 - 0.024 14.8 3.5 0.53 10.4 0.6 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Prothymosin PF03247.9 AET41232.1 - 0.45 10.6 13.4 0.077 13.1 5.7 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family HALZ PF02183.13 AET41232.1 - 1.4 8.7 5.0 0.82 9.4 0.7 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Microtub_assoc PF07989.6 AET41232.1 - 2.7 7.8 6.0 8.2 6.3 1.7 2.3 2 0 0 2 2 2 0 Microtubule associated bZIP_1 PF00170.16 AET41232.1 - 8.9 6.3 7.7 2.8 7.9 2.8 1.9 2 0 0 2 2 2 0 bZIP transcription factor MMR_HSR1 PF01926.18 AET41233.1 - 1.9e-14 53.6 0.1 7.2e-14 51.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AET41233.1 - 0.00043 19.5 0.0 0.00086 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 AET41233.1 - 0.00054 19.2 0.2 0.0023 17.2 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 AET41233.1 - 0.0022 18.4 0.0 0.2 12.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 AET41233.1 - 0.0055 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AET41233.1 - 0.0074 15.7 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 AET41233.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sec23_helical PF04815.10 AET41233.1 - 0.014 14.8 0.1 0.22 10.9 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Dynamin_N PF00350.18 AET41233.1 - 0.016 15.0 0.0 8 6.2 0.0 2.8 2 1 1 3 3 3 0 Dynamin family NTPase_1 PF03266.10 AET41233.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 AET41233.1 - 0.026 13.3 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Septin PF00735.13 AET41233.1 - 0.027 13.5 0.0 0.059 12.3 0.0 1.5 2 0 0 2 2 2 0 Septin GTP_EFTU PF00009.22 AET41233.1 - 0.038 13.4 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 AET41233.1 - 0.056 14.2 0.0 0.19 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 AET41233.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 AET41233.1 - 0.075 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter KTI12 PF08433.5 AET41234.1 - 4.3e-95 317.9 0.8 4.9e-95 317.7 0.5 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 AET41234.1 - 3.9e-07 30.0 0.1 4.3e-06 26.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AET41234.1 - 6e-06 26.5 0.2 0.00047 20.4 0.0 3.0 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AET41234.1 - 3.7e-05 24.5 0.0 0.00022 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 AET41234.1 - 0.0063 16.0 0.1 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein APS_kinase PF01583.15 AET41234.1 - 0.0076 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 AET41234.1 - 0.0088 16.0 0.3 0.17 11.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain FlaG PF03646.10 AET41234.1 - 0.028 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 FlaG protein CPT PF07931.7 AET41234.1 - 0.03 13.9 0.1 0.12 12.0 0.0 1.8 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.16 AET41234.1 - 0.049 12.7 0.0 0.41 9.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 AET41234.1 - 0.053 13.6 0.1 0.37 10.9 0.1 2.7 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 AET41234.1 - 0.12 12.5 0.0 0.72 10.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) mRNA_stabil PF13929.1 AET41235.1 - 4.9e-53 179.9 4.9 7.2e-53 179.4 3.4 1.2 1 0 0 1 1 1 1 mRNA stabilisation Oligomerisation PF02410.10 AET41235.1 - 2.1e-14 53.3 0.0 4.5e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Oligomerisation domain XPG_N PF00752.12 AET41236.1 - 2.1e-35 121.0 0.0 4e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 AET41236.1 - 3.3e-27 94.3 0.0 6.8e-27 93.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 AET41236.1 - 1.1e-06 28.7 0.8 6.3e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold AP_endonuc_2 PF01261.19 AET41238.1 - 6.9e-30 103.9 0.0 8.7e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Pkinase PF00069.20 AET41239.1 - 4.5e-54 183.3 0.4 9.3e-54 182.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41239.1 - 1.9e-22 79.6 0.0 1.5e-21 76.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AET41239.1 - 0.024 14.3 0.8 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 AET41239.1 - 0.043 12.7 0.0 0.19 10.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like FlxA PF14282.1 AET41239.1 - 1.1 9.2 19.6 2.2 8.2 13.6 1.4 1 0 0 1 1 1 0 FlxA-like protein PBP_sp32 PF07222.7 AET41239.1 - 3.3 6.8 13.6 6 5.9 9.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 MscS_TM PF12794.2 AET41239.1 - 5.7 5.4 6.4 9 4.8 4.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Aldose_epim PF01263.15 AET41240.1 - 8.2e-49 166.3 0.3 9.5e-49 166.1 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AntA PF08346.7 AET41241.1 - 0.01 16.0 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 2 AntA/AntB antirepressor DUF4611 PF15387.1 AET41241.1 - 4.6 7.4 9.9 0.72 10.0 4.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-RING_2 PF13639.1 AET41242.1 - 1.5e-08 34.3 7.1 3.1e-08 33.3 4.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AET41242.1 - 1.4e-06 28.3 2.5 3.4e-06 27.0 1.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 AET41242.1 - 7.1e-06 25.8 3.5 2e-05 24.4 2.4 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 AET41242.1 - 0.00085 19.1 1.6 0.002 17.9 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 AET41242.1 - 0.017 15.1 4.9 0.036 14.1 3.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 AET41242.1 - 0.032 14.2 8.3 0.077 13.0 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AET41242.1 - 0.052 13.2 7.1 0.11 12.1 4.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 AET41242.1 - 0.13 12.2 6.3 0.34 10.9 4.3 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.1 AET41242.1 - 0.19 11.4 5.3 0.51 10.0 3.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 AET41242.1 - 0.31 10.8 2.5 19 5.1 0.4 2.5 1 1 1 2 2 2 0 Zinc-binding RING-finger PHD PF00628.24 AET41242.1 - 3 7.6 5.0 5.6 6.7 3.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 AET41242.1 - 5.3 6.7 6.7 83 2.8 4.5 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 AET41243.1 - 4e-26 90.4 1.4 2.6e-14 52.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET41243.1 - 3.6e-21 74.9 0.1 2.8e-12 46.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET41243.1 - 2e-14 53.1 1.4 5.5e-08 32.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_decarbox PF01536.11 AET41244.1 - 1.6e-105 352.4 1.8 1.9e-105 352.2 1.3 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Recep_L_domain PF01030.19 AET41246.1 - 3.5e-10 39.8 12.2 0.012 15.5 0.0 4.7 1 1 3 4 4 4 4 Receptor L domain LRR_4 PF12799.2 AET41246.1 - 0.0013 18.3 2.5 0.0013 18.3 1.7 4.1 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 AET41246.1 - 0.0023 17.5 1.6 0.0055 16.2 0.2 2.0 1 1 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 AET41246.1 - 0.0039 16.9 10.7 0.012 15.3 0.9 4.2 2 2 1 4 4 4 1 Leucine rich repeat LRR_5 PF13306.1 AET41246.1 - 0.086 12.5 9.9 0.054 13.1 0.3 2.9 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) DUF4339 PF14237.1 AET41246.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) GLTP PF08718.6 AET41247.1 - 8.5e-44 149.1 0.0 2.3e-43 147.8 0.0 1.6 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PCI PF01399.22 AET41248.1 - 7.5e-05 22.9 0.1 7.5e-05 22.9 0.1 3.0 3 0 0 3 3 3 1 PCI domain DUF2064 PF09837.4 AET41248.1 - 0.029 13.9 0.0 0.097 12.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) AAA PF00004.24 AET41249.1 - 1.6e-51 173.9 0.0 1.3e-38 132.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AET41249.1 - 7.9e-13 48.1 0.0 4.2e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 AET41249.1 - 1.5e-11 43.7 1.4 4.7e-11 42.1 0.2 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 AET41249.1 - 2.1e-09 37.6 0.9 0.00062 19.9 0.2 3.5 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AET41249.1 - 7.3e-09 35.2 0.6 0.0035 17.0 0.1 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 AET41249.1 - 2.4e-08 34.1 0.1 0.0087 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 AET41249.1 - 2.5e-08 33.0 0.1 0.0013 17.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 AET41249.1 - 1.3e-07 32.4 0.0 0.015 16.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 AET41249.1 - 5.8e-07 28.8 0.1 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AET41249.1 - 9.4e-07 28.6 0.0 0.0014 18.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AET41249.1 - 2.1e-06 27.2 0.2 0.048 13.0 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 AET41249.1 - 3.9e-06 26.7 0.1 0.018 14.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 AET41249.1 - 4.3e-06 26.4 1.7 0.034 13.8 0.0 3.7 4 0 0 4 4 3 1 NACHT domain AAA_2 PF07724.9 AET41249.1 - 4.8e-06 26.5 0.0 0.0015 18.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 AET41249.1 - 5.7e-06 26.4 0.4 0.2 11.7 0.1 4.1 2 1 1 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.11 AET41249.1 - 6.7e-06 25.4 0.0 0.0086 15.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_33 PF13671.1 AET41249.1 - 8.1e-06 25.7 0.0 0.092 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 AET41249.1 - 1.5e-05 24.1 0.1 0.069 12.1 0.1 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 AET41249.1 - 2.2e-05 23.4 0.2 0.16 10.8 0.0 3.6 3 1 1 4 4 4 2 NB-ARC domain AAA_18 PF13238.1 AET41249.1 - 3.1e-05 24.2 0.2 0.022 15.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AET41249.1 - 7.2e-05 22.9 0.0 0.1 12.7 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.21 AET41249.1 - 9.1e-05 21.9 0.1 0.24 10.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF2075 PF09848.4 AET41249.1 - 0.0001 21.3 0.1 0.095 11.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 AET41249.1 - 0.00016 21.9 0.8 0.067 13.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter DEAD PF00270.24 AET41249.1 - 0.00096 18.6 0.3 7.5 6.0 0.0 4.1 2 2 1 4 4 4 0 DEAD/DEAH box helicase Arch_ATPase PF01637.13 AET41249.1 - 0.00098 18.8 0.8 1.7 8.2 0.0 3.5 2 2 1 3 3 3 1 Archaeal ATPase AAA_30 PF13604.1 AET41249.1 - 0.0013 18.2 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 AET41249.1 - 0.0016 18.0 3.4 0.45 10.0 0.3 3.0 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AET41249.1 - 0.0021 17.1 0.1 1.3 8.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 AET41249.1 - 0.0026 18.1 0.3 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 AET41249.1 - 0.0034 16.5 0.7 0.26 10.3 0.0 2.9 3 0 0 3 3 3 1 KaiC Parvo_NS1 PF01057.12 AET41249.1 - 0.0038 16.1 0.0 2.5 6.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 AET41249.1 - 0.004 16.8 0.0 2.7 7.5 0.0 3.2 3 0 0 3 3 3 1 Bacterial dnaA protein ResIII PF04851.10 AET41249.1 - 0.0045 16.8 0.8 1.6 8.5 0.0 2.9 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 AET41249.1 - 0.0046 15.9 0.0 0.74 8.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_11 PF13086.1 AET41249.1 - 0.0049 16.4 0.1 1.9 8.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain Vps4_C PF09336.5 AET41249.1 - 0.0081 16.0 0.2 1.6 8.6 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.1 AET41249.1 - 0.0094 15.3 7.9 2.1 7.7 0.3 4.0 2 2 1 4 4 4 2 AAA domain UPF0079 PF02367.12 AET41249.1 - 0.0094 15.5 0.1 2.7 7.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 AET41249.1 - 0.016 14.7 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 AET41249.1 - 0.031 14.2 0.0 4 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AET41249.1 - 0.042 13.3 0.4 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain RepA_N PF06970.6 AET41249.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus Viral_helicase1 PF01443.13 AET41249.1 - 0.16 11.5 0.0 0.92 8.9 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TcdB_N PF12918.2 AET41250.1 - 0.018 15.1 0.1 0.055 13.5 0.0 1.8 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain FSA_C PF10479.4 AET41250.1 - 0.051 11.6 0.1 0.068 11.2 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PRKCSH PF07915.8 AET41251.1 - 0.00024 21.8 0.0 0.0008 20.1 0.0 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein UQ_con PF00179.21 AET41252.1 - 1.4e-51 173.5 0.0 1.6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AET41252.1 - 5.6e-05 22.9 0.0 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AET41252.1 - 0.00024 20.9 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 AET41252.1 - 0.0096 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain CBF PF03914.12 AET41253.1 - 3.8e-43 146.7 3.3 3.8e-43 146.7 2.3 2.6 3 0 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.6 AET41253.1 - 0.012 15.8 0.3 0.33 11.2 0.0 2.9 2 0 0 2 2 2 0 Nucleolar complex-associated protein TEA PF01285.13 AET41255.1 - 2.4e-33 115.9 1.1 2.4e-33 115.9 0.8 3.9 2 2 1 3 3 3 1 TEA/ATTS domain family FTHFS PF01268.14 AET41256.1 - 1.1e-254 845.6 1.2 1.4e-254 845.2 0.8 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 AET41256.1 - 5.6e-66 220.5 0.2 5.6e-66 220.5 0.2 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AET41256.1 - 3e-34 117.5 0.5 2.4e-33 114.6 0.3 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ribosomal_L19e PF01280.15 AET41257.1 - 9.1e-60 200.7 11.6 9.1e-60 200.7 8.0 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e BNIP2 PF12496.3 AET41258.1 - 0.032 14.3 0.2 0.032 14.3 0.2 1.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Nucleoplasmin PF03066.10 AET41258.1 - 0.69 9.4 4.1 1.2 8.6 2.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin RecR PF02132.10 AET41259.1 - 0.052 12.9 0.5 0.052 12.9 0.3 1.9 2 0 0 2 2 2 0 RecR protein Fungal_trans PF04082.13 AET41260.1 - 8.4e-14 51.0 3.7 2e-13 49.8 2.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET41260.1 - 1.2e-09 37.8 11.8 2.4e-09 36.9 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sporozoite_P67 PF05642.6 AET41260.1 - 0.039 11.8 3.5 0.055 11.3 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 AET41260.1 - 0.51 10.5 8.4 1.1 9.5 5.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Trypan_PARP PF05887.6 AET41260.1 - 1.7 8.4 5.6 3.3 7.5 3.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mito_carr PF00153.22 AET41261.1 - 7.9e-69 227.4 3.7 7.6e-25 86.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.24 AET41263.1 - 3.3e-33 113.1 4.6 2.9e-12 46.0 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 AET41263.1 - 6.2e-25 86.3 7.8 2.3e-07 30.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 AET41263.1 - 2.1e-08 33.5 2.5 0.031 13.8 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 AET41263.1 - 0.053 13.3 1.3 8.6 6.2 0.0 3.0 3 0 0 3 3 3 0 NusA-like KH domain KH_4 PF13083.1 AET41263.1 - 0.25 11.0 3.8 1.2 8.7 0.0 3.2 3 1 1 4 4 4 0 KH domain GTP_cyclohydro2 PF00925.15 AET41265.1 - 1.1e-56 190.7 0.0 8.3e-52 174.8 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II CLASP_N PF12348.3 AET41267.1 - 9.8e-69 231.1 12.3 1.2e-68 230.8 1.0 2.9 3 0 0 3 3 3 2 CLASP N terminal Pol_alpha_B_N PF08418.5 AET41268.1 - 5.1e-61 206.4 0.0 7.7e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 AET41268.1 - 4.7e-48 163.2 0.9 6.4e-48 162.7 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ala_racemase_N PF01168.15 AET41269.1 - 8.8e-38 130.0 0.0 1.1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 AET41270.1 - 3.1e-88 296.3 15.6 3.9e-88 296.0 10.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 AET41270.1 - 4.1e-05 23.8 0.3 0.00012 22.3 0.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 AET41270.1 - 0.0014 18.5 0.0 0.0045 16.9 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain AP4E_app_platf PF14807.1 AET41270.1 - 0.03 14.5 0.1 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Rep_fac_C PF08542.6 AET41271.1 - 2.2e-18 65.9 0.7 5.7e-18 64.6 0.1 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AET41271.1 - 1.5e-12 47.4 0.0 3.7e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AET41271.1 - 6e-06 26.4 0.1 1.7e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 AET41271.1 - 0.00094 18.7 0.0 0.0025 17.3 0.0 1.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 AET41271.1 - 0.0085 15.1 0.0 0.24 10.4 0.0 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AET41271.1 - 0.013 15.6 0.3 0.082 13.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 AET41271.1 - 0.026 14.5 0.1 5.6 7.0 0.0 2.5 1 1 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 AET41271.1 - 0.2 11.0 0.6 2.7 7.3 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain Ribosomal_L16 PF00252.13 AET41272.1 - 5.3e-36 123.2 0.5 7.8e-36 122.7 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA-synt_2d PF01409.15 AET41273.1 - 3.8e-45 154.0 0.1 5.2e-25 88.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 AET41273.1 - 2.5e-25 88.4 0.0 1.5e-24 86.0 0.0 2.2 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Phage_connector PF05352.7 AET41273.1 - 0.0074 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Phage Connector (GP10) tRNA-synt_2 PF00152.15 AET41273.1 - 0.033 12.9 0.5 5.7 5.6 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) FAD_binding_1 PF00667.15 AET41274.1 - 2e-28 99.3 0.0 3.8e-28 98.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AET41274.1 - 1.8e-18 66.9 0.0 3.5e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 AET41274.1 - 1.4e-14 54.5 0.0 2.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain G5 PF07501.7 AET41274.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 G5 domain ATG11 PF10377.4 AET41275.1 - 1.3e-37 128.5 0.0 1.3e-37 128.5 0.0 2.8 3 1 1 4 4 4 1 Autophagy-related protein 11 CENP-F_leu_zip PF10473.4 AET41275.1 - 0.0041 16.9 3.6 0.0041 16.9 2.5 4.0 3 1 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Acetyltransf_1 PF00583.19 AET41276.1 - 3.8e-19 68.4 0.0 5.5e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AET41276.1 - 4.8e-09 36.2 0.0 7.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AET41276.1 - 1.7e-08 34.4 0.0 2.2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AET41276.1 - 2.5e-08 34.0 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AET41276.1 - 2.8e-08 33.3 0.1 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 AET41276.1 - 2.4e-05 24.4 0.0 2.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AET41276.1 - 6.1e-05 22.8 0.0 0.00014 21.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AET41276.1 - 0.0027 17.5 0.1 0.0045 16.8 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 AET41276.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PCNA_C PF02747.10 AET41277.1 - 8.1e-48 161.5 0.6 6e-47 158.7 0.1 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 AET41277.1 - 1.9e-47 159.9 2.0 3.5e-47 159.0 0.8 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 AET41277.1 - 2.8e-08 32.8 0.6 6.1e-06 25.2 0.5 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 AET41277.1 - 6.4e-06 25.4 0.0 7.5e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 FOP_dimer PF09398.5 AET41277.1 - 0.023 14.6 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 FOP N terminal dimerisation domain DNA_pol3_beta_3 PF02768.10 AET41277.1 - 0.081 12.5 0.1 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain HMG_box PF00505.14 AET41278.1 - 5e-26 90.7 1.0 5e-26 90.7 0.7 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AET41278.1 - 6.7e-20 71.2 1.3 6.7e-20 71.2 0.9 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 AET41278.1 - 0.0027 17.4 0.8 0.0027 17.4 0.5 1.9 2 1 1 3 3 3 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 AET41278.1 - 0.0061 16.7 0.3 0.017 15.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) CHDNT PF08073.7 AET41278.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.8 AET41278.1 - 0.034 14.4 0.5 0.043 14.0 0.3 1.3 1 1 0 1 1 1 0 YABBY protein zf-CCHC PF00098.18 AET41279.1 - 5.7e-05 22.8 42.7 0.001 18.8 1.7 5.2 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.1 AET41279.1 - 0.05 13.2 0.9 0.05 13.2 0.6 5.4 4 1 1 5 5 5 0 Zinc knuckle tRNA-synt_2b PF00587.20 AET41280.1 - 1.2e-46 158.5 0.7 2.1e-46 157.6 0.5 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AET41280.1 - 4.2e-17 61.8 0.8 9.6e-17 60.7 0.6 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 AET41280.1 - 2.3e-13 49.7 0.0 4.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 AET41280.1 - 1.2e-10 41.0 0.0 2.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain DUF1689 PF07954.6 AET41281.1 - 6.5e-47 159.1 2.2 8.5e-47 158.8 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) DUF2629 PF10945.3 AET41281.1 - 0.076 12.3 0.1 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2629) Coatomer_E PF04733.9 AET41282.1 - 5.9e-09 35.5 10.4 1.8e-08 33.9 7.2 2.0 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 AET41282.1 - 0.00014 22.1 2.3 0.64 10.3 0.0 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 AET41282.1 - 0.059 14.0 0.8 11 7.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 AET41282.1 - 1.8 8.7 10.3 2.2 8.4 0.3 3.6 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 GET2 PF08690.5 AET41283.1 - 1.2e-85 287.3 0.6 1.5e-85 287.1 0.4 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 Ribosomal_S15 PF00312.17 AET41284.1 - 3.6e-26 90.7 0.3 9.8e-26 89.3 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein S15 PRTase_3 PF15610.1 AET41284.1 - 0.019 13.9 0.5 0.032 13.1 0.4 1.3 1 0 0 1 1 1 0 PRTase ComF-like DUF3487 PF11990.3 AET41284.1 - 0.13 11.6 0.1 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Abhydrolase_1 PF00561.15 AET41285.1 - 1.5e-17 63.9 0.0 7.4e-15 55.1 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AET41285.1 - 1.2e-07 31.8 0.0 1.1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 AET41285.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase ING PF12998.2 AET41286.1 - 1.9e-19 69.8 3.6 3.9e-19 68.8 2.5 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 AET41286.1 - 2e-10 40.2 9.0 3.3e-10 39.4 6.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 AET41286.1 - 0.0011 19.0 1.3 0.0027 17.8 0.9 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain DUF2296 PF10058.4 AET41286.1 - 0.13 12.0 2.3 0.27 10.9 1.6 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C4_Topoisom PF01396.14 AET41286.1 - 0.2 11.2 5.6 3.1 7.3 0.5 2.8 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger UPF0449 PF15136.1 AET41286.1 - 0.71 10.1 0.0 0.71 10.1 0.0 2.6 3 1 0 3 3 3 0 Uncharacterised protein family UPF0449 DUF4112 PF13430.1 AET41287.1 - 2.1e-29 101.5 1.5 2.6e-29 101.2 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) EcsC PF12787.2 AET41287.1 - 0.82 9.0 2.6 4.6 6.5 0.0 2.7 2 1 1 3 3 3 0 EcsC protein family Fcf1 PF04900.7 AET41288.1 - 9.1e-37 125.2 0.8 1.2e-36 124.8 0.1 1.5 2 0 0 2 2 2 1 Fcf1 Ribosomal_S4e PF00900.15 AET41289.1 - 2.5e-32 110.3 1.1 1.7e-31 107.6 0.5 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 AET41289.1 - 9.8e-20 70.1 4.1 2e-19 69.1 2.8 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 AET41289.1 - 1.1e-07 31.1 0.8 2.6e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 AET41289.1 - 2.9e-05 23.6 1.2 2.9e-05 23.6 0.8 3.6 4 0 0 4 4 4 1 KOW motif Pkinase PF00069.20 AET41290.1 - 8.6e-69 231.5 0.0 1.4e-68 230.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41290.1 - 1.9e-30 105.8 0.0 3e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AET41290.1 - 3.2e-12 46.7 2.4 9.4e-12 45.2 1.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AET41290.1 - 2.1e-09 36.7 0.0 4.5e-09 35.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 AET41290.1 - 1.9e-06 27.6 0.0 7.2e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 C2 domain YrbL-PhoP_reg PF10707.4 AET41290.1 - 0.017 14.4 0.0 0.056 12.7 0.0 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HSF_DNA-bind PF00447.12 AET41291.1 - 8.3e-37 125.5 4.0 2.1e-36 124.2 2.8 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 AET41291.1 - 9.9e-28 96.3 0.3 2.4e-27 95.1 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain VacA2 PF03077.9 AET41291.1 - 0.05 13.2 0.7 0.12 12.0 0.5 1.6 1 0 0 1 1 1 0 Putative vacuolating cytotoxin SET PF00856.23 AET41292.1 - 9.6e-10 38.9 0.1 9.6e-10 38.9 0.1 2.6 2 1 0 2 2 2 1 SET domain Myticin-prepro PF10690.4 AET41292.1 - 0.28 11.2 12.4 1.5 8.9 2.1 2.7 2 1 0 2 2 2 0 Myticin pre-proprotein from the mussel Motilin_assoc PF04643.7 AET41293.1 - 0.025 14.0 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide Cytochrom_C_asm PF01578.15 AET41293.1 - 0.053 13.0 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C assembly protein 5-FTHF_cyc-lig PF01812.15 AET41294.1 - 1.6e-34 119.3 0.0 1.8e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Aminotran_4 PF01063.14 AET41295.1 - 1.4e-28 99.9 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV TauD PF02668.11 AET41296.1 - 4.8e-49 167.3 1.5 6.6e-49 166.8 1.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 AET41297.1 - 2.5e-16 59.3 20.0 3.8e-16 58.7 13.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 AET41297.1 - 0.002 17.8 0.4 0.0061 16.3 0.3 1.9 1 0 0 1 1 1 1 MFS_1 like family Sas10_Utp3 PF04000.10 AET41298.1 - 5.1e-11 42.6 3.8 5.1e-11 42.6 2.7 1.9 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Rpp20 PF12328.3 AET41298.1 - 2.2 7.9 9.5 3.1 7.4 4.8 2.3 2 1 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Thioredoxin_7 PF13899.1 AET41299.1 - 9e-19 67.2 0.2 1.8e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 AET41299.1 - 2.3e-15 56.4 0.0 4.4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 AET41299.1 - 4.4e-12 45.3 0.0 1.8e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain Thioredox_DsbH PF03190.10 AET41299.1 - 0.016 14.9 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Peptidase_C13 PF01650.13 AET41300.1 - 2.9e-46 157.8 2.9 3e-46 157.8 1.2 1.5 2 0 0 2 2 2 1 Peptidase C13 family Pkinase PF00069.20 AET41301.1 - 2.7e-52 177.4 0.2 1e-51 175.5 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41301.1 - 1.5e-25 89.7 0.1 3.7e-24 85.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AET41301.1 - 1.2e-05 24.4 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ResIII PF04851.10 AET41302.1 - 3.6e-19 69.3 0.1 1.7e-18 67.0 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AET41302.1 - 1.6e-16 60.2 0.0 3.5e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET41302.1 - 1.1e-11 44.4 0.0 3e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AET41302.1 - 0.00081 19.5 0.0 0.0031 17.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 AET41302.1 - 0.0014 17.4 0.0 0.0027 16.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 AET41302.1 - 0.0029 16.6 0.0 0.0069 15.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 AET41302.1 - 0.14 10.7 1.2 0.25 9.9 0.1 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2731 PF10806.3 AET41303.1 - 4.4e-36 123.8 0.7 8.7e-36 122.9 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) STE PF02200.11 AET41304.1 - 2.3e-60 201.5 2.5 4e-60 200.7 1.7 1.4 1 0 0 1 1 1 1 STE like transcription factor Tcf25 PF04910.9 AET41305.1 - 3.3e-75 253.2 2.0 6.2e-75 252.3 1.4 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_2 PF07719.12 AET41305.1 - 0.038 13.8 4.5 0.059 13.3 0.4 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 AET41305.1 - 0.087 13.5 0.1 0.59 10.8 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 AET41305.1 - 1.6 8.5 5.4 0.33 10.6 0.5 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ipi1_N PF12333.3 AET41306.1 - 1.4e-23 82.7 0.0 3.2e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation RRM_1 PF00076.17 AET41307.1 - 3.4e-44 148.3 0.0 8.2e-18 63.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET41307.1 - 5e-27 93.6 0.0 5.2e-10 39.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET41307.1 - 1.6e-17 63.0 0.0 8.8e-10 38.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AET41307.1 - 0.00028 20.7 0.0 0.00081 19.2 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 AET41307.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Neur_chan_memb PF02932.11 AET41307.1 - 0.36 10.6 2.7 0.63 9.8 1.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 AET41307.1 - 0.75 9.2 12.9 1.4 8.3 8.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO REC114-like PF15165.1 AET41307.1 - 2.6 7.7 12.3 5.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like Tubulin_3 PF14881.1 AET41307.1 - 4 6.8 5.3 6.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Tubulin domain zf-C2H2 PF00096.21 AET41308.1 - 2.8e-07 30.4 15.3 0.00017 21.7 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET41308.1 - 2.6e-05 24.2 3.5 2.6e-05 24.2 2.4 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET41308.1 - 0.00053 20.1 14.4 0.036 14.3 1.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 AET41308.1 - 0.0014 18.7 2.7 0.08 13.1 0.4 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AET41308.1 - 0.0037 17.3 2.6 0.028 14.5 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 AET41308.1 - 5.1 7.5 8.6 6.8 7.1 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain RhoGEF PF00621.15 AET41309.1 - 3e-11 43.5 0.1 5.6e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain ABC2_membrane PF01061.19 AET41310.1 - 2.1e-85 285.1 53.7 3e-43 147.4 11.4 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 AET41310.1 - 5.3e-40 135.2 0.2 1.4e-34 117.8 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 AET41310.1 - 2.1e-35 121.9 0.0 2.2e-16 60.4 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_trans_N PF14510.1 AET41310.1 - 6e-20 71.1 0.0 1.8e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 AET41310.1 - 2.1e-08 33.7 2.1 9.2e-06 25.1 0.1 3.0 4 0 0 4 4 4 2 AAA domain ABC2_membrane_3 PF12698.2 AET41310.1 - 2.2e-08 33.5 40.8 2.7e-06 26.6 8.3 3.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 AET41310.1 - 3.3e-07 30.4 0.6 6.9e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 AET41310.1 - 5.2e-05 22.9 0.1 0.57 9.9 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain DUF258 PF03193.11 AET41310.1 - 5.7e-05 22.3 0.0 0.0035 16.5 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AET41310.1 - 0.00032 20.1 1.5 0.0035 16.8 0.2 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain NACHT PF05729.7 AET41310.1 - 0.0004 20.0 0.2 0.42 10.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 AET41310.1 - 0.0012 19.1 0.1 0.68 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AET41310.1 - 0.0046 16.9 0.4 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AET41310.1 - 0.0047 17.0 0.2 0.66 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AET41310.1 - 0.0058 16.5 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 AET41310.1 - 0.0073 16.2 0.0 0.11 12.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 AET41310.1 - 0.01 15.0 0.0 1.9 7.6 0.0 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 AET41310.1 - 0.013 14.9 4.3 0.85 9.0 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 AET41310.1 - 0.021 15.6 0.0 5.2 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AET41310.1 - 0.032 13.8 0.5 1.6 8.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 AET41310.1 - 0.036 14.4 0.0 0.036 14.4 0.0 2.9 4 0 0 4 4 3 0 AAA domain Arch_ATPase PF01637.13 AET41310.1 - 0.079 12.6 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 AET41310.1 - 0.21 11.0 1.0 3.1 7.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 AET41310.1 - 0.27 10.7 0.5 13 5.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain Brix PF04427.13 AET41311.1 - 3.6e-42 144.1 2.4 5.7e-42 143.5 1.7 1.3 1 0 0 1 1 1 1 Brix domain SPOUT_MTase_2 PF14419.1 AET41311.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP PEX-1N PF09262.6 AET41312.1 - 0.07 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal MMR_HSR1 PF01926.18 AET41313.1 - 2.1e-15 56.6 0.0 5.2e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AET41313.1 - 1.9e-05 23.9 0.0 3.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 AET41313.1 - 2.2e-05 23.7 0.1 6.1e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 AET41313.1 - 6.1e-05 22.9 0.2 0.1 12.4 0.0 2.7 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 AET41313.1 - 8.8e-05 22.0 0.0 0.00045 19.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AET41313.1 - 0.00065 18.9 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AET41313.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiG_C PF01890.11 AET41313.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus Gar1 PF04410.9 AET41314.1 - 3e-44 150.2 1.2 3.9e-44 149.8 0.1 1.7 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region DHO_dh PF01180.16 AET41315.1 - 1.7e-96 322.6 0.1 2e-96 322.4 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 AET41315.1 - 3.8e-06 25.9 0.0 0.012 14.5 0.0 2.7 2 1 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.12 AET41315.1 - 0.01 15.1 0.1 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 PcrB family BING4CT PF08149.6 AET41316.1 - 1.2e-37 127.2 0.0 2.7e-35 119.7 0.0 3.3 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 AET41316.1 - 1.7e-08 34.0 0.0 2.1e-05 24.1 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 AET41316.1 - 0.007 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region PC_rep PF01851.17 AET41317.1 - 1e-42 141.9 19.7 2e-06 27.6 0.8 10.3 11 0 0 11 11 11 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 AET41317.1 - 4.4e-19 68.5 4.0 8e-13 48.4 0.0 5.0 3 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 AET41317.1 - 5.8e-08 32.1 0.5 0.46 10.7 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 AET41317.1 - 1.4e-05 25.4 3.3 0.66 10.5 0.0 5.3 4 2 2 6 6 6 3 HEAT-like repeat RICTOR_V PF14668.1 AET41317.1 - 0.053 13.4 0.1 1.3 8.9 0.0 3.4 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 PBP_sp32 PF07222.7 AET41317.1 - 0.15 11.1 2.1 0.26 10.4 1.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TPR_2 PF07719.12 AET41317.1 - 0.24 11.3 2.4 1 9.4 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 AET41317.1 - 0.28 11.0 3.5 0.86 9.5 0.9 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT_PBS PF03130.11 AET41317.1 - 2.6 8.7 4.9 40 5.0 0.0 4.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat 2-Hacid_dh_C PF02826.14 AET41318.1 - 6e-53 178.6 0.0 9.5e-53 177.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AET41318.1 - 9.4e-37 125.4 0.0 1.2e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 AET41318.1 - 0.00037 19.8 0.0 0.00096 18.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.10 AET41318.1 - 0.00049 19.9 1.2 0.00088 19.1 0.2 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 AET41318.1 - 0.0052 16.6 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acetyltransf_1 PF00583.19 AET41318.1 - 0.047 13.7 0.0 0.23 11.5 0.0 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family SPO22 PF08631.5 AET41319.1 - 2e-58 197.6 28.7 4.1e-57 193.3 3.0 4.7 3 2 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 AET41319.1 - 0.0035 17.2 0.5 4.4 7.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 AET41319.1 - 0.02 14.7 0.6 12 6.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat NAD_binding_5 PF07994.7 AET41319.1 - 0.034 13.6 0.1 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase PPR PF01535.15 AET41319.1 - 0.27 11.2 1.7 15 5.8 0.2 4.1 4 0 0 4 4 4 0 PPR repeat APH PF01636.18 AET41320.1 - 5.1e-10 39.4 0.0 3.4e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AET41320.1 - 0.014 14.4 0.0 0.46 9.5 0.0 2.6 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Orexin_rec2 PF03827.8 AET41320.1 - 0.082 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Orexin receptor type 2 HORMA PF02301.13 AET41322.1 - 5.5e-51 173.0 1.2 1.2e-50 171.9 0.1 2.1 3 0 0 3 3 3 1 HORMA domain PHD_2 PF13831.1 AET41322.1 - 0.012 14.9 3.8 0.029 13.6 2.6 1.6 1 0 0 1 1 1 0 PHD-finger Peptidase_M24 PF00557.19 AET41323.1 - 6.8e-52 176.0 0.0 9.5e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AET41323.1 - 1.4e-31 108.6 0.0 3.1e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NAD_binding_8 PF13450.1 AET41323.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Hormone_1 PF00103.15 AET41324.1 - 0.079 12.2 1.5 0.17 11.1 1.0 1.5 1 0 0 1 1 1 0 Somatotropin hormone family PPR_2 PF13041.1 AET41325.1 - 5.6e-12 45.4 2.8 2.9e-10 39.9 0.1 4.0 3 1 1 4 4 4 1 PPR repeat family YopJ PF03421.11 AET41325.1 - 0.00034 20.5 0.1 0.00097 19.0 0.1 1.8 1 1 0 1 1 1 1 YopJ Serine/Threonine acetyltransferase Sec8_exocyst PF04048.9 AET41325.1 - 0.19 11.3 8.1 0.14 11.7 3.4 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain PPR_1 PF12854.2 AET41325.1 - 1.6 8.2 4.6 13 5.3 0.0 3.5 4 0 0 4 4 4 0 PPR repeat MAM33 PF02330.11 AET41326.1 - 1.1e-44 152.6 5.2 1.3e-44 152.3 3.6 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cons_hypoth95 PF03602.10 AET41326.1 - 0.013 14.9 0.0 0.031 13.6 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pox_RNA_pol_35 PF03396.10 AET41326.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 35 kD subunit Pmp3 PF01679.12 AET41327.1 - 8.4e-17 60.6 7.7 1.1e-16 60.2 5.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UPF0029 PF01205.14 AET41329.1 - 8.6e-31 105.8 0.0 1.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 VitD-bind_III PF09164.5 AET41329.1 - 0.028 14.0 0.1 0.11 12.0 0.0 2.0 1 1 1 2 2 2 0 Vitamin D binding protein, domain III FAD-oxidase_C PF02913.14 AET41330.1 - 3.4e-57 193.6 0.0 4.6e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AET41330.1 - 1.1e-35 122.0 0.1 2e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AA_permease PF00324.16 AET41331.1 - 1.7e-119 399.3 33.5 2e-119 399.0 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET41331.1 - 1.9e-33 115.6 34.9 2.3e-33 115.3 24.2 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 AET41331.1 - 0.093 12.8 0.1 0.093 12.8 0.1 3.6 3 1 0 3 3 3 0 PrgI family protein HIT PF01230.18 AET41332.1 - 1.5e-24 86.3 0.2 2.1e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AET41332.1 - 3.2e-11 43.4 0.9 6.7e-11 42.4 0.6 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AET41332.1 - 0.084 12.5 1.5 0.21 11.2 1.0 1.7 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 AAA PF00004.24 AET41333.1 - 1.8e-98 325.8 0.0 2.4e-48 163.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AET41333.1 - 2.7e-17 62.5 1.4 6.4e-17 61.2 0.5 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 AET41333.1 - 1.5e-13 50.3 0.0 1.5e-05 24.1 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AET41333.1 - 1.9e-13 50.6 0.4 4.9e-07 29.8 0.0 3.0 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AET41333.1 - 1.3e-12 47.6 1.6 3e-06 27.0 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AET41333.1 - 1.2e-11 44.9 0.0 0.0011 19.0 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 AET41333.1 - 2.4e-11 43.7 0.0 9e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AET41333.1 - 4.1e-11 43.7 0.6 0.0013 19.5 0.0 4.0 5 0 0 5 5 2 2 AAA domain AAA_22 PF13401.1 AET41333.1 - 2.5e-10 40.6 3.3 0.0012 18.9 0.1 4.2 3 2 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 AET41333.1 - 1.2e-09 37.6 0.1 6.9e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 AET41333.1 - 2.4e-09 36.3 0.0 0.0014 17.4 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 AET41333.1 - 1.7e-08 34.4 0.0 0.0028 17.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 AET41333.1 - 6.3e-08 32.2 0.0 0.0067 15.8 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 AET41333.1 - 9.9e-08 31.6 6.2 0.0028 17.1 0.2 4.4 2 2 1 3 3 3 2 AAA domain RNA_helicase PF00910.17 AET41333.1 - 2.2e-07 30.9 0.0 0.01 16.0 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_19 PF13245.1 AET41333.1 - 2.8e-07 30.1 1.0 0.024 14.3 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 AET41333.1 - 3.4e-07 29.6 0.4 0.027 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 AET41333.1 - 6.6e-07 28.6 0.0 0.0079 15.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin KaiC PF06745.8 AET41333.1 - 1.3e-06 27.6 1.1 0.27 10.2 0.0 3.7 2 1 1 3 3 3 2 KaiC AAA_24 PF13479.1 AET41333.1 - 3.1e-06 26.9 0.1 0.11 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 AET41333.1 - 8.5e-06 25.7 0.0 0.0068 16.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 AET41333.1 - 8.7e-06 25.7 0.3 0.25 11.3 0.0 3.1 3 1 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 AET41333.1 - 1.1e-05 24.9 0.1 0.11 11.9 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 AET41333.1 - 1.1e-05 25.7 0.1 0.023 15.0 0.0 3.7 3 1 0 3 3 2 1 ABC transporter AAA_18 PF13238.1 AET41333.1 - 1.2e-05 25.5 0.1 0.19 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain PhoH PF02562.11 AET41333.1 - 1.3e-05 24.5 0.2 0.098 11.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.12 AET41333.1 - 3.1e-05 22.9 0.1 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 AET41333.1 - 4.1e-05 23.6 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.5 AET41333.1 - 4.4e-05 23.2 0.2 0.00068 19.4 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.8 AET41333.1 - 9e-05 21.5 0.0 0.17 10.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 AET41333.1 - 0.00012 21.9 0.1 0.5 10.0 0.1 3.7 2 2 1 3 3 3 1 Archaeal ATPase AAA_11 PF13086.1 AET41333.1 - 0.00012 21.7 0.0 0.43 10.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 AET41333.1 - 0.00012 21.6 0.0 0.67 9.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 AET41333.1 - 0.00013 21.7 0.0 0.2 11.2 0.0 2.9 3 0 0 3 3 2 1 Bacterial dnaA protein NACHT PF05729.7 AET41333.1 - 0.00027 20.6 0.2 1.7 8.3 0.0 3.5 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 AET41333.1 - 0.00053 19.0 0.0 0.69 8.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 AET41333.1 - 0.0011 18.6 0.0 1.9 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 AET41333.1 - 0.0086 14.9 1.6 1.8 7.3 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain KAP_NTPase PF07693.9 AET41333.1 - 0.014 14.3 0.2 1.7 7.5 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain IPT PF01745.11 AET41333.1 - 0.015 14.5 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.10 AET41333.1 - 0.02 14.6 1.4 3.4 7.3 0.0 3.7 4 0 0 4 4 3 0 NTPase Zot PF05707.7 AET41333.1 - 0.022 14.2 0.3 5.8 6.3 0.0 3.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.17 AET41333.1 - 0.027 14.3 0.1 4.7 7.0 0.0 3.2 3 0 0 3 3 3 0 Shikimate kinase UPF0079 PF02367.12 AET41333.1 - 0.04 13.5 0.1 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 AET41333.1 - 0.088 12.2 0.3 24 4.3 0.0 3.4 3 1 0 4 4 3 0 DEAD/DEAH box helicase KTI12 PF08433.5 AET41333.1 - 0.14 11.3 0.1 13 4.9 0.0 2.6 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Cyclin_N PF00134.18 AET41334.1 - 3.8e-16 58.8 0.1 7.5e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 AET41334.1 - 6.9e-10 39.5 0.7 2e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Cyclin DUF717 PF05338.7 AET41334.1 - 0.015 15.2 0.4 0.05 13.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF717) Na_Ca_ex PF01699.19 AET41335.1 - 4.3e-49 165.7 33.8 1.8e-24 85.9 6.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein FA_desaturase PF00487.19 AET41335.1 - 7.2 5.9 7.9 2.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Fatty acid desaturase Ycf9 PF01737.12 AET41336.1 - 2.7 7.5 6.9 0.34 10.3 0.4 2.7 3 0 0 3 3 3 0 YCF9 Ribosomal_60s PF00428.14 AET41338.1 - 1.8e-20 73.1 11.1 2.4e-20 72.6 7.7 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein IATP PF04568.7 AET41339.1 - 5.3e-19 68.1 0.3 5.6e-19 68.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Spc7 PF08317.6 AET41339.1 - 0.0061 15.2 2.7 0.0067 15.1 1.9 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Fib_alpha PF08702.5 AET41339.1 - 0.012 15.7 0.2 0.012 15.6 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FbpA PF05833.6 AET41339.1 - 0.015 13.8 1.8 0.015 13.8 1.3 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) COQ7 PF03232.8 AET41339.1 - 0.08 12.4 0.2 0.086 12.3 0.2 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DIX PF00778.12 AET41339.1 - 0.12 12.1 0.4 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 DIX domain Pox_A_type_inc PF04508.7 AET41339.1 - 0.15 11.8 2.5 0.21 11.4 0.3 2.1 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat Bap31 PF05529.7 AET41339.1 - 0.16 11.3 1.4 0.18 11.2 1.0 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PspB PF06667.7 AET41339.1 - 0.22 11.4 2.3 0.3 11.0 1.6 1.1 1 0 0 1 1 1 0 Phage shock protein B CorA PF01544.13 AET41339.1 - 0.32 9.9 1.9 0.37 9.7 1.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein WD40 PF00400.27 AET41340.1 - 8e-10 38.2 16.0 0.0016 18.2 0.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat HMGL-like PF00682.14 AET41341.1 - 7.4e-74 248.3 0.2 1.4e-73 247.5 0.2 1.5 1 0 0 1 1 1 1 HMGL-like Focal_AT PF03623.8 AET41341.1 - 0.025 14.0 0.3 0.55 9.7 0.3 2.6 2 0 0 2 2 2 0 Focal adhesion targeting region Cullin PF00888.17 AET41342.1 - 4.7e-149 497.6 19.4 5.9e-149 497.3 13.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AET41342.1 - 1.4e-24 85.6 2.5 1.6e-24 85.5 0.4 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain MARVEL PF01284.18 AET41343.1 - 0.00061 19.6 2.5 0.00099 18.9 1.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3671 PF12420.3 AET41343.1 - 0.085 12.8 3.3 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF4131 PF13567.1 AET41343.1 - 0.71 9.2 5.5 2.9 7.2 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Mit_KHE1 PF10173.4 AET41344.1 - 5.1e-54 182.9 1.1 7.3e-54 182.4 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Etmic-2 PF06670.6 AET41344.1 - 0.085 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 Ribosomal_L41 PF05162.8 AET41345.1 - 4.4e-10 39.0 24.7 4.6e-10 38.9 17.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 ATP-synt_ab PF00006.20 AET41346.1 - 7.5e-119 394.9 0.1 1.5e-118 393.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.11 AET41346.1 - 5.3e-53 179.9 0.0 8e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint ATP-synt_ab_C PF00306.22 AET41346.1 - 2.9e-18 66.4 0.1 5.7e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AET41346.1 - 1.1e-15 57.5 2.3 3e-15 56.1 1.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Hom_end PF05204.9 AET41346.1 - 7.3e-15 54.8 0.2 8.5e-13 48.2 0.1 3.2 2 1 0 2 2 2 1 Homing endonuclease Hint PF01079.15 AET41346.1 - 0.00074 18.7 0.0 0.0018 17.5 0.0 1.6 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.1 AET41346.1 - 0.018 14.9 0.0 0.061 13.2 0.0 1.9 2 0 0 2 2 2 0 Hint domain DUF3415 PF11895.3 AET41347.1 - 0.11 12.3 0.6 13 5.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3415) Metallophos PF00149.23 AET41348.1 - 7.6e-40 136.4 0.4 9.9e-40 136.0 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 AET41349.1 - 1.3e-64 217.3 1.1 1.6e-64 217.0 0.8 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor R3H PF01424.17 AET41350.1 - 4.4e-10 39.0 1.2 4.9e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 R3H domain DUF4175 PF13779.1 AET41350.1 - 4.8 4.7 20.0 7.2 4.1 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) IncA PF04156.9 AET41350.1 - 5.1 6.6 11.7 9 5.8 8.1 1.4 1 0 0 1 1 1 0 IncA protein Ufd2P_core PF10408.4 AET41351.1 - 5.3e-193 642.7 11.0 7.7e-193 642.1 7.6 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 AET41351.1 - 6.1e-27 93.3 1.3 1.7e-26 91.9 0.9 1.8 1 0 0 1 1 1 1 U-box domain Ribosomal_L29 PF00831.18 AET41352.1 - 5.8e-17 61.1 3.4 5.8e-17 61.1 2.4 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein Annexin PF00191.15 AET41352.1 - 0.093 12.6 0.5 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 Annexin MRP-L47 PF06984.8 AET41352.1 - 0.13 12.1 3.3 0.17 11.7 0.8 2.3 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4404 PF14357.1 AET41352.1 - 0.25 11.8 2.1 1.2 9.5 1.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) PilJ PF13675.1 AET41352.1 - 0.49 10.7 2.8 0.84 9.9 0.4 1.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Snapin_Pallidin PF14712.1 AET41352.1 - 2.8 8.3 9.2 0.55 10.5 3.7 1.8 2 0 0 2 2 2 0 Snapin/Pallidin Arf PF00025.16 AET41353.1 - 1.9e-79 264.9 0.0 2.1e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AET41353.1 - 4.9e-15 55.2 0.0 6.1e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AET41353.1 - 6.8e-14 51.5 0.0 7.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AET41353.1 - 1.1e-12 47.3 0.8 8.4e-10 37.8 0.1 2.2 1 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AET41353.1 - 7e-12 44.9 0.0 8.4e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AET41353.1 - 3.7e-11 43.5 0.0 4.8e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AET41353.1 - 6.9e-06 26.0 0.0 9.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AET41353.1 - 0.0045 16.4 0.1 0.021 14.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 AET41353.1 - 0.0058 16.0 0.5 0.011 15.1 0.1 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 AET41353.1 - 0.0078 16.1 0.1 0.013 15.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 AET41353.1 - 0.029 14.0 0.6 3.3 7.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 AET41353.1 - 0.029 13.8 0.3 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 6PF2K PF01591.13 AET41353.1 - 0.057 12.4 1.1 0.28 10.1 0.8 1.9 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DBD_Tnp_Mut PF03108.10 AET41353.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 MuDR family transposase PduV-EutP PF10662.4 AET41353.1 - 0.11 11.9 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 AET41353.1 - 0.12 12.7 0.1 0.25 11.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.12 AET41353.1 - 0.15 11.4 1.1 0.91 8.8 0.2 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_17 PF13207.1 AET41353.1 - 0.19 12.5 0.8 0.54 11.0 0.5 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 AET41354.1 - 2.6e-36 124.4 0.0 3e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AET41354.1 - 2.4e-07 30.1 0.0 4.3e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AET41354.1 - 0.0036 16.7 0.0 0.029 13.7 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 AET41354.1 - 0.0038 17.7 0.0 0.045 14.2 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 AET41354.1 - 0.0086 14.8 1.2 0.015 13.9 0.2 1.7 2 0 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 AET41354.1 - 0.0089 15.4 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 AET41354.1 - 0.033 13.6 0.4 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 AET41354.1 - 0.086 12.8 0.0 3.3 7.6 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Prenyltransf PF01255.14 AET41355.1 - 1.2e-05 24.6 0.0 2.5e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CD52 PF15116.1 AET41355.1 - 0.044 13.5 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 CAMPATH-1 antigen DUF1003 PF06210.6 AET41355.1 - 0.045 13.6 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Sugar_tr PF00083.19 AET41356.1 - 8.5e-117 390.4 28.1 1e-116 390.2 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AET41356.1 - 7.1e-14 51.2 38.6 1.3e-10 40.5 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec31 PF11549.3 AET41357.1 - 1.1e-21 76.1 0.7 3.4e-21 74.6 0.5 1.9 1 0 0 1 1 1 1 Protein transport protein SEC31 WD40 PF00400.27 AET41357.1 - 4.4e-18 64.3 3.0 1.1e-05 25.0 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat SRA1 PF07304.6 AET41357.1 - 5e-10 39.3 2.2 3.9e-09 36.4 0.0 3.0 1 1 1 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 AET41357.1 - 8.1e-06 25.7 1.0 1.4e-05 25.0 0.7 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 BBS2_Mid PF14783.1 AET41357.1 - 0.029 14.1 0.2 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Prp18 PF02840.10 AET41357.1 - 0.053 13.3 1.0 0.16 11.8 0.0 2.3 2 1 0 2 2 2 0 Prp18 domain EKR PF10371.4 AET41358.1 - 0.1 12.1 0.5 0.36 10.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function Scm3 PF10384.4 AET41359.1 - 2.4e-24 84.5 0.9 8.9e-24 82.7 0.7 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 Pro_isomerase PF00160.16 AET41360.1 - 1.6e-46 158.3 0.8 2.5e-46 157.6 0.2 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.12 AET41360.1 - 2.2e-06 27.1 1.3 0.00052 19.7 0.8 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 AET41360.1 - 9.6e-06 25.1 2.3 0.012 15.2 1.5 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 AET41360.1 - 1.2e-05 24.7 1.5 2.8e-05 23.5 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AET41360.1 - 0.014 15.1 0.3 0.041 13.6 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 AET41360.1 - 0.015 15.1 0.1 0.041 13.7 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 AET41360.1 - 0.13 12.7 1.1 0.6 10.7 0.3 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 AET41360.1 - 0.28 11.3 3.6 0.26 11.4 1.5 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RNA_pol_Rpb1_1 PF04997.7 AET41361.1 - 3e-121 404.7 0.0 6.4e-121 403.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 AET41361.1 - 1.1e-108 362.7 0.2 1.7e-108 362.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 AET41361.1 - 4.8e-73 244.5 0.0 1.1e-72 243.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 AET41361.1 - 1.4e-62 210.7 0.7 1.4e-62 210.7 0.5 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 AET41361.1 - 1e-49 168.3 0.1 1.8e-48 164.2 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 AET41361.1 - 8.3e-47 158.2 3.7 1.8e-46 157.1 2.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 AET41361.1 - 9.9e-36 121.7 0.1 2.6e-35 120.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 AET41361.1 - 2.6e-15 55.0 305.1 0.2 11.8 4.9 16.0 7 2 1 16 16 16 14 RNA polymerase Rpb1 C-terminal repeat BPL_N PF09825.4 AET41362.1 - 1.1e-122 409.3 0.0 1.4e-122 409.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 AET41362.1 - 6.3e-14 52.0 0.1 1.1e-12 48.0 0.1 2.3 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 AET41362.1 - 6.1e-12 45.0 0.0 1.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain CDP-OH_P_transf PF01066.16 AET41363.1 - 2.1e-15 56.8 4.0 2.1e-15 56.8 2.8 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cpn60_TCP1 PF00118.19 AET41364.1 - 1.1e-131 439.8 13.3 1.2e-131 439.6 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 AET41364.1 - 0.074 12.3 1.4 1.9 7.7 0.0 2.9 3 0 0 3 3 3 0 DeoC/LacD family aldolase D123 PF07065.9 AET41365.1 - 1.9e-103 345.6 0.2 2.4e-103 345.3 0.1 1.1 1 0 0 1 1 1 1 D123 FAD_binding_8 PF08022.7 AET41366.1 - 1.7e-22 79.2 0.0 3.2e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 AET41366.1 - 6.4e-18 65.0 16.7 1e-17 64.3 7.9 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 AET41366.1 - 2.2e-15 56.8 0.0 4.6e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain LRR_8 PF13855.1 AET41366.1 - 0.06 13.1 0.2 0.18 11.5 0.2 1.8 1 0 0 1 1 1 0 Leucine rich repeat CFEM PF05730.6 AET41366.1 - 0.24 11.2 1.7 0.66 9.8 1.2 1.8 1 0 0 1 1 1 0 CFEM domain DUF4405 PF14358.1 AET41366.1 - 3.1 7.9 17.1 0.072 13.2 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Glyco_hydro_16 PF00722.16 AET41367.1 - 1.3e-44 151.6 0.3 2.1e-44 151.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 AET41367.1 - 0.29 11.1 11.7 0.57 10.2 8.1 1.4 1 0 0 1 1 1 0 Chitin recognition protein Coatomer_WDAD PF04053.9 AET41368.1 - 1.1e-134 449.6 4.2 1.6e-134 449.0 2.9 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 AET41368.1 - 5.8e-64 216.1 0.0 8.3e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 AET41368.1 - 1.1e-56 186.7 15.4 1.6e-10 40.4 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 AET41368.1 - 0.00027 20.6 0.3 0.93 9.1 0.0 3.8 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AET41368.1 - 0.00086 17.5 4.1 0.63 8.1 0.0 3.6 2 1 2 4 4 4 3 Nucleoporin Nup120/160 CNH PF00780.17 AET41368.1 - 0.0065 15.9 0.3 0.017 14.5 0.1 1.8 2 0 0 2 2 2 1 CNH domain Membrane_bind PF14564.1 AET41368.1 - 0.034 14.3 0.3 2.4 8.4 0.2 2.9 2 1 0 2 2 2 0 Membrane binding HDPD PF02924.9 AET41368.1 - 0.099 12.4 0.3 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D Tubulin PF00091.20 AET41369.1 - 5.9e-67 225.6 0.0 9e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AET41369.1 - 1.7e-29 102.3 0.2 3.7e-29 101.3 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 AET41369.1 - 5e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF2013 PF09431.5 AET41370.1 - 3.3e-41 140.3 13.1 3.3e-41 140.3 9.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) DUF2216 PF10226.4 AET41371.1 - 0.0075 15.7 1.3 0.0075 15.7 0.9 2.1 2 0 0 2 2 2 1 Uncharacterized conserved proteins (DUF2216) DUF1465 PF07323.7 AET41371.1 - 0.016 14.8 0.6 0.016 14.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) bZIP_1 PF00170.16 AET41371.1 - 0.17 11.8 11.6 0.095 12.6 1.1 2.8 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.13 AET41371.1 - 0.2 11.3 3.4 0.71 9.6 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spectrin PF00435.16 AET41371.1 - 0.22 11.8 14.7 0.049 13.9 3.5 2.5 2 1 0 2 2 2 0 Spectrin repeat GD_AH_C PF04295.8 AET41371.1 - 0.27 9.8 1.8 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 D-galactarate dehydratase / Altronate hydrolase, C terminus Speriolin_N PF15058.1 AET41371.1 - 0.79 9.5 8.4 0.51 10.2 1.2 2.8 2 1 0 2 2 2 0 Speriolin N terminus CENP-Q PF13094.1 AET41371.1 - 1 9.3 13.6 4.3 7.3 1.6 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 AET41371.1 - 9.1 6.6 15.4 0.21 11.9 2.4 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF972) PCI PF01399.22 AET41372.1 - 1.2e-21 76.9 2.1 1.9e-21 76.3 0.0 2.3 3 0 0 3 3 3 1 PCI domain Nop14 PF04147.7 AET41373.1 - 7.7e-226 751.9 40.4 5e-224 745.9 28.0 2.0 1 1 0 1 1 1 1 Nop14-like family APG9 PF04109.11 AET41374.1 - 4.5e-164 545.7 4.5 6.1e-164 545.3 3.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Sas10 PF09368.5 AET41375.1 - 2.5e-30 104.4 9.8 1.1e-29 102.4 6.8 2.2 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 AET41375.1 - 3.3e-10 40.0 0.7 9.9e-10 38.4 0.0 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family FAM75 PF14650.1 AET41375.1 - 9.6 5.4 8.6 4.2 6.6 2.9 2.5 2 0 0 2 2 2 0 FAM75 family MutS_V PF00488.16 AET41376.1 - 4.1e-55 186.7 0.0 6e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AET41376.1 - 1.4e-33 116.3 1.2 2.8e-33 115.4 0.8 1.5 1 0 0 1 1 1 1 MutS domain III DUF3785 PF12653.2 AET41376.1 - 0.0024 17.7 0.6 0.11 12.4 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3785) AAA_29 PF13555.1 AET41376.1 - 0.016 14.7 0.1 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cyclin_N PF00134.18 AET41377.1 - 6.7e-42 142.0 2.4 9.8e-42 141.5 0.5 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AET41377.1 - 1.1e-29 102.7 0.2 3.2e-29 101.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain HLH PF00010.21 AET41378.1 - 1.1e-12 47.4 0.9 1.1e-12 47.4 0.6 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 AET41379.1 - 2.2e-29 101.9 16.2 2.9e-29 101.5 11.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF627 PF04781.7 AET41379.1 - 0.076 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Arrestin_C PF02752.17 AET41380.1 - 8.8e-20 71.2 0.0 6.4e-19 68.4 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Adaptin_N PF01602.15 AET41381.1 - 4.5e-98 328.8 17.8 4.5e-98 328.8 12.3 1.3 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 AET41381.1 - 1.7e-07 31.5 1.5 3.9e-07 30.3 1.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Arm PF00514.18 AET41381.1 - 0.054 13.3 1.1 18 5.3 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 AET41381.1 - 0.12 12.3 3.2 0.17 11.7 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) TB2_DP1_HVA22 PF03134.14 AET41382.1 - 7e-32 109.0 5.2 9.4e-32 108.6 3.6 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Peptidase_M22 PF00814.20 AET41383.1 - 3.2e-84 282.6 0.0 3.8e-84 282.3 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 AET41383.1 - 0.0045 16.1 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase DASH_Spc34 PF08657.5 AET41384.1 - 1.3e-67 228.1 1.6 1.6e-67 227.9 1.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Spc34 HALZ PF02183.13 AET41384.1 - 0.0012 18.5 2.6 0.0048 16.5 0.5 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper PaaX_C PF08223.6 AET41384.1 - 0.025 14.2 0.3 0.038 13.6 0.2 1.2 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Scaffolding_pro PF11418.3 AET41384.1 - 0.027 14.7 0.3 0.59 10.4 0.1 2.5 2 0 0 2 2 2 0 Phi29 scaffolding protein PspB PF06667.7 AET41384.1 - 0.048 13.5 0.7 0.16 11.9 0.5 1.8 1 0 0 1 1 1 0 Phage shock protein B DUF904 PF06005.7 AET41384.1 - 0.37 11.1 8.5 1.6 9.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF3450 PF11932.3 AET41384.1 - 1.9 7.6 9.1 1.7 7.8 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) WD40 PF00400.27 AET41385.1 - 4.8e-38 127.6 8.8 3.4e-09 36.2 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 AET41385.1 - 4.1e-09 35.1 5.9 0.00077 17.7 0.0 4.4 2 2 2 4 4 4 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 AET41385.1 - 2.2e-05 24.2 0.4 0.0013 18.4 0.0 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Mdv1 PF11542.3 AET41385.1 - 4e-05 23.4 0.1 8.7e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial division protein 1 DUF3249 PF11615.3 AET41385.1 - 0.0064 16.2 0.1 1.4 8.6 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3249) Nucleoporin_N PF08801.6 AET41385.1 - 0.02 13.6 0.4 4.9 5.7 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like Nefa_Nip30_N PF10187.4 AET41386.1 - 0.062 13.4 10.6 0.029 14.5 5.9 1.5 1 1 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Phage_lysis PF03245.8 AET41386.1 - 0.11 12.4 1.1 0.15 12.0 0.8 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Toxin_43 PF15604.1 AET41386.1 - 0.13 12.3 5.0 0.18 11.8 3.5 1.3 1 0 0 1 1 1 0 Putative toxin 43 LAG1-DNAbind PF09271.6 AET41386.1 - 0.39 11.1 6.2 0.72 10.3 4.3 1.5 1 1 0 1 1 1 0 LAG1, DNA binding DnaJ PF00226.26 AET41387.1 - 4.9e-18 64.6 0.9 9.9e-18 63.6 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain PigN PF04987.9 AET41388.1 - 2.4e-128 428.5 45.5 3.1e-128 428.1 31.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 AET41388.1 - 9.4e-15 54.7 0.2 1.7e-12 47.3 0.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AET41388.1 - 5.3e-11 42.2 0.0 1.6e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 AET41388.1 - 0.00058 19.3 0.1 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Pkinase PF00069.20 AET41389.1 - 1.2e-69 234.3 0.0 1.4e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41389.1 - 1.3e-39 135.8 0.0 1.7e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET41389.1 - 1e-05 24.6 0.0 1.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AET41389.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AET41389.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 AET41389.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family L51_S25_CI-B8 PF05047.11 AET41390.1 - 1.9e-12 46.6 0.3 3e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LrgB PF04172.11 AET41391.1 - 1.5e-22 79.8 2.2 1.5e-22 79.8 1.5 3.0 2 2 0 2 2 2 2 LrgB-like family LrgA PF03788.9 AET41391.1 - 0.0013 18.4 3.5 0.0013 18.4 2.4 2.4 2 0 0 2 2 2 1 LrgA family Pkinase PF00069.20 AET41392.1 - 1.7e-50 171.6 0.0 4.4e-50 170.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41392.1 - 2.9e-18 65.8 0.0 2.1e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AET41392.1 - 0.024 13.6 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribosomal_L14 PF00238.14 AET41393.1 - 9.8e-44 148.0 2.2 1.1e-43 147.8 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Mitoc_L55 PF09776.4 AET41393.1 - 0.014 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Pkinase PF00069.20 AET41394.1 - 1.8e-37 128.8 0.0 9.3e-25 87.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AET41394.1 - 1.8e-21 76.3 0.0 2.4e-18 66.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AET41394.1 - 0.0058 15.6 0.0 0.43 9.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like UcrQ PF02939.11 AET41395.1 - 3.5e-35 119.6 0.9 5.3e-35 119.1 0.7 1.3 1 0 0 1 1 1 1 UcrQ family Crl PF07417.7 AET41395.1 - 0.18 11.5 0.7 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator Crl polyprenyl_synt PF00348.12 AET41396.1 - 7.1e-79 264.3 0.0 8.5e-79 264.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ebp2 PF05890.7 AET41397.1 - 1.2e-84 283.8 30.8 1.2e-84 283.8 21.4 2.2 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 GYD PF08734.6 AET41397.1 - 0.12 12.1 0.7 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 GYD domain GTP_EFTU PF00009.22 AET41398.1 - 4.8e-31 107.6 0.0 6.8e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AET41398.1 - 8e-18 64.0 0.0 2e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 AET41398.1 - 6.6e-17 61.1 0.0 2.7e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 AET41398.1 - 2.4e-06 27.5 0.1 5.4e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AET41398.1 - 7.8e-06 25.6 0.0 2.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 AET41398.1 - 3.6e-05 24.2 0.0 8.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AA_permease PF00324.16 AET41399.1 - 7.2e-54 182.8 39.0 9.4e-54 182.5 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET41399.1 - 8.5e-31 106.9 40.5 1.1e-30 106.6 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease Zip PF02535.17 AET41400.1 - 7.3e-23 81.0 7.9 1.2e-21 77.0 4.9 2.4 1 1 0 1 1 1 1 ZIP Zinc transporter Fig1 PF12351.3 AET41400.1 - 0.012 15.4 0.2 0.033 14.0 0.1 1.8 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 FMN_red PF03358.10 AET41401.1 - 0.19 11.2 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 NADPH-dependent FMN reductase SRI PF08236.6 AET41402.1 - 5.1e-28 96.8 3.3 5.1e-28 96.8 2.3 2.6 2 1 1 3 3 3 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 AET41402.1 - 1.8e-22 80.4 0.7 1.8e-22 80.4 0.5 3.5 2 2 0 2 2 2 1 SET domain OmpH PF03938.9 AET41402.1 - 0.49 10.3 14.7 0.92 9.4 10.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2252 PF10009.4 AET41402.1 - 1.9 7.2 8.8 3.9 6.2 6.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Churchill PF06573.6 AET41403.1 - 0.93 9.5 4.6 0.22 11.5 0.7 1.8 2 0 0 2 2 2 0 Churchill protein DUF2401 PF10287.4 AET41404.1 - 1.7e-83 279.7 0.0 2.1e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 AET41404.1 - 3.8e-25 87.8 0.0 1e-24 86.4 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) XPA_C PF05181.7 AET41404.1 - 0.43 10.2 3.7 3 7.4 0.1 3.0 2 1 1 3 3 3 0 XPA protein C-terminus STE3 PF02076.10 AET41405.1 - 1.1e-93 313.4 21.7 1.3e-93 313.1 15.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor Peptidase_M20 PF01546.23 AET41406.1 - 6e-26 91.1 0.0 9e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AET41406.1 - 3.6e-13 49.2 0.0 5.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain PX PF00787.19 AET41406.1 - 0.041 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 PX domain Rep_fac-A_3 PF08661.6 AET41408.1 - 8e-28 96.5 0.0 8.8e-28 96.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 KRE9 PF05390.6 AET41409.1 - 3.4e-29 101.3 6.7 7.2e-29 100.2 4.6 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 AET41409.1 - 6.7e-07 29.6 0.0 4.4e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SWIRM PF04433.12 AET41410.1 - 1e-32 112.0 0.2 2.3e-32 110.9 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 AET41410.1 - 3.7e-09 36.5 0.0 1.3e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AET41410.1 - 9.6e-09 35.1 0.1 2.1e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prefoldin_2 PF01920.15 AET41411.1 - 3.6e-15 55.6 9.3 4.4e-15 55.3 6.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit RimK PF08443.6 AET41411.1 - 0.031 13.7 0.7 0.039 13.4 0.5 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF4239 PF14023.1 AET41411.1 - 0.083 12.2 1.1 0.1 11.9 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) RuvB_C PF05491.8 AET41411.1 - 0.087 12.4 0.6 1.5 8.4 0.2 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB C-terminus IFT57 PF10498.4 AET41411.1 - 0.14 10.8 7.4 0.27 9.9 5.1 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 YlqD PF11068.3 AET41411.1 - 0.53 10.3 11.5 13 5.8 3.6 2.0 1 1 0 1 1 1 0 YlqD protein Toxin_43 PF15604.1 AET41411.1 - 0.67 9.9 6.2 0.12 12.3 1.6 1.7 2 0 0 2 2 2 0 Putative toxin 43 DUF948 PF06103.6 AET41411.1 - 7.8 6.4 9.2 4.6 7.1 2.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ATP12 PF07542.6 AET41412.1 - 8.1e-28 96.8 0.0 2e-27 95.5 0.0 1.6 2 0 0 2 2 2 1 ATP12 chaperone protein DUF1664 PF07889.7 AET41413.1 - 0.015 15.1 0.3 0.034 13.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Glyco_transf_34 PF05637.7 AET41414.1 - 2.3e-42 145.1 0.1 2.9e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Gon7 PF08738.5 AET41415.1 - 3.5e-32 110.4 1.6 4e-32 110.2 1.1 1.1 1 0 0 1 1 1 1 Gon7 family SSB PF00436.20 AET41416.1 - 9e-19 67.2 0.0 1.1e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF1506 PF07405.6 AET41417.1 - 0.093 12.7 0.0 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1506) muHD PF10291.4 AET41418.1 - 9.9e-67 224.8 0.5 3.4e-66 223.0 0.0 2.0 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Baculo_PEP_C PF04513.7 AET41418.1 - 0.022 14.5 0.1 0.072 12.9 0.1 1.9 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.1 AET41418.1 - 0.81 10.1 4.5 11 6.4 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Mannosyl_trans3 PF11051.3 AET41419.1 - 6.1e-80 268.4 0.0 9.8e-80 267.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Pkinase PF00069.20 AET41420.1 - 5.5e-46 156.8 0.0 8.4e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41420.1 - 5.3e-28 97.8 0.0 8.2e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MOZART2 PF12926.2 AET41420.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Ribosomal_L39 PF00832.15 AET41421.1 - 6.5e-23 79.9 10.2 7.7e-23 79.6 7.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_S8 PF00410.14 AET41422.1 - 2.3e-26 92.1 0.1 3.2e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.14 AET41423.1 - 2.3e-40 137.2 1.1 2.7e-40 136.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 AET41423.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) DUF2012 PF09430.5 AET41424.1 - 0.077 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Beach PF02138.13 AET41425.1 - 7.2e-108 360.1 0.1 7.2e-108 360.1 0.1 2.5 3 0 0 3 3 3 1 Beige/BEACH domain PH_BEACH PF14844.1 AET41425.1 - 6.5e-10 38.7 0.0 1.9e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 AET41425.1 - 0.0045 17.2 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily AAA_22 PF13401.1 AET41426.1 - 2e-11 44.1 0.0 5.2e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AET41426.1 - 3.4e-10 40.2 0.2 1.1e-09 38.6 0.2 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AET41426.1 - 1.2e-06 28.6 0.1 8.8e-05 22.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.6 AET41426.1 - 9.3e-06 25.2 0.1 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 CDC6, C terminal KAP_NTPase PF07693.9 AET41426.1 - 0.00038 19.5 0.5 0.017 14.1 0.2 2.7 2 1 0 3 3 3 1 KAP family P-loop domain AAA_11 PF13086.1 AET41426.1 - 0.00056 19.5 0.2 0.0011 18.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AET41426.1 - 0.00078 19.1 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 AET41426.1 - 0.0037 16.9 0.0 0.013 15.2 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 AET41426.1 - 0.015 15.1 0.0 0.69 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 AET41426.1 - 0.023 13.6 0.5 0.35 9.7 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase DUF2075 PF09848.4 AET41426.1 - 0.025 13.5 0.2 0.063 12.2 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 AET41426.1 - 0.033 13.8 0.9 5 6.7 0.1 2.9 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.17 AET41426.1 - 0.035 14.2 0.1 0.54 10.4 0.0 2.7 1 1 0 1 1 1 0 RNA helicase T2SE PF00437.15 AET41426.1 - 0.051 12.4 0.0 0.12 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 AET41426.1 - 0.37 10.1 1.5 7 6.0 1.0 2.2 1 1 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.26 AET41427.1 - 2.1e-16 59.6 0.0 2.4e-08 33.9 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AET41427.1 - 3.7e-05 23.7 0.3 0.035 14.1 0.1 3.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain ELO PF01151.13 AET41428.1 - 5.5e-64 215.8 24.5 6.7e-64 215.5 17.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family RNase_PH PF01138.16 AET41429.1 - 1.2e-24 87.1 0.9 3.8e-23 82.2 0.3 2.6 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AET41429.1 - 0.039 13.9 0.1 0.089 12.7 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PfkB PF00294.19 AET41430.1 - 4.5e-44 150.7 0.1 1.4e-43 149.1 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase UCH PF00443.24 AET41431.1 - 8.7e-89 297.2 0.0 6e-88 294.4 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AET41431.1 - 4.2e-20 72.3 1.2 7.1e-12 45.3 0.1 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 AET41431.1 - 0.25 11.7 13.2 0.046 14.1 0.5 4.7 4 2 0 4 4 4 0 DUSP domain SPX PF03105.14 AET41432.1 - 7.7e-44 150.5 14.5 3.2e-43 148.4 8.8 2.0 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 AET41432.1 - 1.3e-21 77.0 48.1 1.7e-21 76.6 33.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 AET41432.1 - 7.4e-14 51.0 48.8 2.3e-13 49.4 19.2 2.2 1 1 1 2 2 2 2 Citrate transporter Mt_ATP-synt_B PF05405.9 AET41432.1 - 1.2 8.5 7.5 0.4 10.1 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Aconitase PF00330.15 AET41433.1 - 3.4e-169 563.2 0.0 8.6e-169 561.8 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AET41433.1 - 4.4e-42 143.3 0.0 7.3e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain RasGEF PF00617.14 AET41434.1 - 2.7e-45 154.4 3.7 3.2e-45 154.1 1.1 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 AET41434.1 - 2.3e-15 56.5 1.1 1.1e-14 54.3 0.3 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 AET41434.1 - 0.00048 19.4 0.6 0.0014 17.9 0.0 2.1 3 0 0 3 3 3 1 SH3 domain Ish1 PF10281.4 AET41435.1 - 2.8e-35 120.0 34.4 2.3e-13 49.9 1.6 7.5 7 0 0 7 7 7 6 Putative stress-responsive nuclear envelope protein HeH PF12949.2 AET41435.1 - 1.7e-06 27.4 0.0 0.56 9.7 0.0 4.1 4 0 0 4 4 4 3 HeH/LEM domain SAP PF02037.22 AET41435.1 - 0.0017 17.7 0.0 54 3.4 0.0 5.1 6 0 0 6 6 6 0 SAP domain DUF883 PF05957.8 AET41435.1 - 0.44 10.9 3.8 4.7 7.6 0.2 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) COX14 PF14880.1 AET41436.1 - 3e-25 87.6 3.1 3.1e-25 87.5 2.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF1772 PF08592.6 AET41436.1 - 0.073 12.8 0.0 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Bac_rhamnosid_N PF08531.5 AET41436.1 - 0.092 12.2 0.1 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Rtf2 PF04641.7 AET41437.1 - 1.4e-21 76.8 1.1 2.5e-21 76.0 0.7 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger Vinculin PF01044.14 AET41437.1 - 0.039 11.9 0.1 0.051 11.5 0.0 1.1 1 0 0 1 1 1 0 Vinculin family zf-CCCH PF00642.19 AET41438.1 - 1.3e-08 34.2 12.1 9.8e-06 25.1 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 AET41438.1 - 7.6e-07 28.8 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AET41438.1 - 0.00034 20.1 0.0 0.00065 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET41438.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LRV_FeS PF05484.6 AET41438.1 - 0.099 12.2 3.2 1.6 8.3 0.3 2.3 2 0 0 2 2 2 0 LRV protein FeS4 cluster Proteasome PF00227.21 AET41439.1 - 6.4e-59 198.4 0.0 8.2e-59 198.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AET41439.1 - 4.3e-09 35.5 0.7 8e-09 34.6 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Utp14 PF04615.8 AET41440.1 - 3.1e-201 670.3 72.5 3.1e-201 670.3 50.2 1.6 2 0 0 2 2 2 1 Utp14 protein Prefoldin PF02996.12 AET41441.1 - 8.2e-28 96.4 1.2 1.2e-27 95.9 0.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit Omptin PF01278.15 AET41441.1 - 0.044 12.8 0.3 0.061 12.4 0.2 1.1 1 0 0 1 1 1 0 Omptin family DUF406 PF04175.7 AET41441.1 - 0.052 14.0 4.9 0.065 13.7 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF406) DUF4241 PF14025.1 AET41441.1 - 0.13 12.0 1.0 0.27 10.9 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4241) Uds1 PF15456.1 AET41441.1 - 1 9.3 9.4 0.42 10.6 3.4 2.1 2 0 0 2 2 2 0 Up-regulated During Septation PRKCSH-like PF12999.2 AET41441.1 - 1.2 8.6 5.3 0.28 10.7 1.4 1.7 2 0 0 2 2 2 0 Glucosidase II beta subunit-like Fib_alpha PF08702.5 AET41441.1 - 4.6 7.3 12.5 2.6 8.1 0.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family YlqD PF11068.3 AET41441.1 - 5.2 7.1 21.3 2.8 7.9 1.0 2.1 2 0 0 2 2 2 0 YlqD protein Rad10 PF03834.9 AET41442.1 - 6.8e-26 89.7 0.2 1.3e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Asn_synthase PF00733.16 AET41443.1 - 2.6e-45 154.8 0.0 4.2e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 AET41443.1 - 6.2e-11 42.1 0.6 3.1e-08 33.3 0.1 3.8 2 2 1 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.1 AET41443.1 - 2.8e-09 37.0 0.1 1.5e-07 31.3 0.0 3.1 2 2 0 3 3 3 1 Glutamine amidotransferase domain DUF3700 PF12481.3 AET41443.1 - 0.015 14.5 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein ERO1 PF04137.10 AET41444.1 - 2.5e-120 401.7 0.2 3.3e-120 401.3 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF2800 PF10926.3 AET41444.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) TFIID-18kDa PF02269.11 AET41445.1 - 1.5e-30 104.8 0.0 2.4e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 AET41445.1 - 0.001 19.1 0.0 0.0037 17.3 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Aerolysin PF01117.15 AET41445.1 - 0.006 15.5 0.0 0.0063 15.4 0.0 1.1 1 0 0 1 1 1 1 Aerolysin toxin TAF PF02969.12 AET41445.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) GLTSCR1 PF15249.1 AET41445.1 - 0.085 12.9 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region Fungal_trans_2 PF11951.3 AET41446.1 - 1.7e-106 356.0 3.4 2.2e-106 355.7 2.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AET41446.1 - 1.7e-12 47.0 6.2 3.9e-12 45.8 4.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fb_signal PF08341.6 AET41446.1 - 0.031 14.2 1.1 0.39 10.7 0.0 2.8 2 0 0 2 2 2 0 Fibronectin-binding protein signal sequence MIF4G_like_2 PF09090.6 AET41447.1 - 0.066 12.4 0.1 0.072 12.3 0.1 1.1 1 0 0 1 1 1 0 MIF4G like Peroxin-3 PF04882.7 AET41448.1 - 1.9e-109 366.2 11.6 2.2e-109 366.0 8.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Ada3 PF10198.4 AET41448.1 - 0.049 13.3 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Skp1 PF01466.14 AET41449.1 - 3.3e-36 123.1 0.6 6.4e-36 122.2 0.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 AET41449.1 - 1.2e-12 47.7 0.2 2.9e-11 43.2 0.1 2.3 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain GRAM PF02893.15 AET41450.1 - 7e-20 70.3 0.0 5.3e-18 64.2 0.0 2.6 2 0 0 2 2 2 2 GRAM domain PP1_bind PF15276.1 AET41450.1 - 0.26 11.3 5.1 2.8 8.0 0.7 3.2 3 0 0 3 3 3 0 Protein phosphatase 1 binding Pkinase PF00069.20 AET41451.1 - 9.4e-43 146.2 0.1 2.1e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 AET41451.1 - 1.3e-41 141.4 0.7 3.1e-41 140.2 0.5 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 AET41451.1 - 3.6e-20 72.1 0.0 1.5e-18 66.8 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 AET41451.1 - 2.3e-05 23.7 0.1 0.29 10.7 0.0 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 AET41451.1 - 9.9e-05 21.9 0.0 0.013 14.9 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain Kdo PF06293.9 AET41451.1 - 0.003 16.6 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sec62 PF03839.11 AET41451.1 - 9.2 5.6 14.7 24 4.2 10.2 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Cnd3 PF12719.2 AET41452.1 - 3.8e-99 331.4 3.8 3.8e-99 331.4 2.7 3.7 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 AET41452.1 - 1.7e-12 47.4 0.3 3.2e-07 30.5 0.0 4.1 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 AET41452.1 - 4e-09 35.7 1.5 0.17 12.0 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 AET41452.1 - 0.0013 19.1 0.6 4.2 7.9 0.1 4.8 5 1 0 5 5 5 1 HEAT-like repeat ABA_GPCR PF12430.3 AET41453.1 - 7.9e-53 178.5 4.1 7.9e-53 178.5 2.8 2.4 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 AET41453.1 - 2.6e-16 59.4 1.3 7.5e-16 57.9 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) FYVE PF01363.16 AET41454.1 - 4.9e-20 71.2 21.4 2.1e-15 56.3 1.5 2.8 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 AET41454.1 - 0.00039 19.9 0.4 0.0008 18.9 0.3 1.5 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2H2_4 PF13894.1 AET41454.1 - 0.18 12.2 0.0 0.18 12.2 0.0 5.0 6 1 0 6 6 6 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 AET41454.1 - 0.23 11.4 0.1 0.23 11.4 0.1 4.3 6 0 0 6 6 6 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 AET41454.1 - 0.8 9.8 8.7 0.26 11.4 0.2 3.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MIF4G PF02854.14 AET41455.1 - 3.9e-44 150.5 22.6 3.9e-18 65.6 4.7 3.7 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 AET41455.1 - 2.1e-17 63.4 45.1 8.3e-14 51.7 31.3 2.7 1 1 0 1 1 1 1 Up-frameshift suppressor 2 Daxx PF03344.10 AET41455.1 - 0.048 12.1 30.0 0.09 11.2 20.8 1.4 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 AET41455.1 - 0.16 11.0 31.7 0.36 9.8 22.0 1.6 1 0 0 1 1 1 0 BUD22 DUF3537 PF12056.3 AET41455.1 - 1 7.9 6.4 0.66 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) Nop14 PF04147.7 AET41455.1 - 6.4 4.5 43.2 14 3.4 29.9 1.6 1 0 0 1 1 1 0 Nop14-like family SpoIIE PF07228.7 AET41456.1 - 1.6e-30 106.3 0.0 2.1e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 AET41456.1 - 3.1e-06 26.7 0.4 0.001 18.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 AET41456.1 - 0.0027 17.1 0.4 0.0085 15.5 0.3 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C ATP-synt_E PF05680.7 AET41457.1 - 1.3e-17 63.5 0.1 1.3e-17 63.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain PBP PF01161.15 AET41458.1 - 1.1e-13 51.2 0.1 2.2e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF2146 PF10220.4 AET41458.1 - 0.061 11.3 0.6 1.7 6.5 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2146) Peptidase_M1 PF01433.15 AET41459.1 - 3.3e-117 391.9 0.9 1.3e-115 386.5 0.4 2.8 2 1 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 AET41459.1 - 2.4e-29 102.6 0.0 3.8e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AET41459.1 - 6.1e-15 55.3 0.0 1.5e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Abhydrolase_6 PF12697.2 AET41460.1 - 7.9e-19 68.4 0.0 1.1e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AET41460.1 - 2.1e-12 47.0 0.0 3.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AET41460.1 - 2e-09 37.3 0.0 3.9e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 AET41460.1 - 0.00013 20.4 0.2 0.032 12.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 AET41460.1 - 0.00019 21.0 0.1 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) DUF2305 PF10230.4 AET41460.1 - 0.00024 20.6 0.1 0.00035 20.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 AET41460.1 - 0.0028 17.4 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 1 Putative lysophospholipase Thioesterase PF00975.15 AET41460.1 - 0.0032 17.7 0.0 0.13 12.5 0.0 2.6 2 1 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 AET41460.1 - 0.0041 16.7 0.3 0.011 15.3 0.2 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 AET41460.1 - 0.0045 16.2 0.0 0.0078 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) BAAT_C PF08840.6 AET41460.1 - 0.0046 16.6 0.0 0.89 9.2 0.1 2.5 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.8 AET41460.1 - 0.0087 15.6 0.0 0.098 12.2 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Cutinase PF01083.17 AET41460.1 - 0.023 14.4 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 AET41460.1 - 0.058 12.7 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) VirJ PF06057.6 AET41460.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) CN_hydrolase PF00795.17 AET41461.1 - 4.7e-25 88.0 0.0 8e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 AET41461.1 - 7.4e-21 74.1 0.0 2.1e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 AET41461.1 - 0.0075 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Asparaginase PF00710.15 AET41462.1 - 3.3e-69 233.1 0.0 4.3e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ribosomal_L19 PF01245.15 AET41462.1 - 0.0069 16.1 0.0 21 4.9 0.0 3.5 3 0 0 3 3 3 2 Ribosomal protein L19 Oxysterol_BP PF01237.13 AET41463.1 - 8.1e-103 343.6 1.9 1.3e-102 342.9 0.2 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 AET41463.1 - 5.8e-32 109.6 0.4 1.9e-31 107.9 0.2 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DASH_Dad4 PF08650.5 AET41464.1 - 1.1e-36 124.5 5.3 1.2e-36 124.3 3.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DUF3251 PF11622.3 AET41464.1 - 0.002 17.5 0.4 0.0023 17.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3251) NPV_P10 PF05531.7 AET41464.1 - 0.016 15.4 0.1 0.018 15.2 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prenyltransf PF01255.14 AET41464.1 - 0.018 14.2 0.3 0.019 14.1 0.2 1.0 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Peripla_BP_2 PF01497.13 AET41464.1 - 0.021 13.9 0.0 0.021 13.9 0.0 1.0 1 0 0 1 1 1 0 Periplasmic binding protein CagA PF03507.8 AET41464.1 - 0.033 14.0 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 CagA exotoxin DivIC PF04977.10 AET41464.1 - 0.063 12.7 0.5 0.091 12.2 0.3 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF2450 PF10475.4 AET41464.1 - 0.073 11.9 0.3 0.08 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DUF4206 PF13901.1 AET41464.1 - 0.08 12.4 0.2 0.085 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) FAM117 PF15388.1 AET41464.1 - 0.17 11.0 0.6 0.18 10.9 0.4 1.1 1 0 0 1 1 1 0 Protein Family FAM117 Nop10p PF04135.7 AET41465.1 - 3e-21 74.8 0.1 3.2e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family IncA PF04156.9 AET41466.1 - 0.0056 16.2 0.0 0.0079 15.8 0.0 1.1 1 0 0 1 1 1 1 IncA protein PTPLA PF04387.9 AET41466.1 - 0.016 14.6 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA ATP-synt_8 PF00895.15 AET41466.1 - 0.11 12.6 0.5 0.34 11.1 0.1 2.0 2 0 0 2 2 2 0 ATP synthase protein 8 ASC PF00858.19 AET41466.1 - 0.16 10.6 0.6 0.17 10.5 0.4 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel TPR_12 PF13424.1 AET41467.1 - 4.6e-09 36.0 0.1 2.7e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 AET41467.1 - 1.1e-05 25.0 0.2 0.00021 20.8 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AET41467.1 - 0.0018 18.0 0.5 4.1 7.5 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AET41467.1 - 0.0032 17.0 0.3 13 5.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 AET41467.1 - 0.0083 15.8 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Apc3 PF12895.2 AET41467.1 - 0.025 14.6 1.0 8.1 6.6 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Prenyltrans_2 PF13249.1 AET41468.1 - 1.1e-26 93.4 0.2 2.1e-11 44.2 0.0 5.2 2 1 3 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 AET41468.1 - 1.2e-20 73.5 0.0 6.6e-14 51.8 0.0 5.4 4 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans PF00432.16 AET41468.1 - 6.4e-20 70.4 4.1 1.4e-07 30.9 0.5 4.5 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 AET41468.1 - 2.5e-05 23.6 0.1 1.4 8.0 0.0 4.2 3 1 1 4 4 4 2 Pectic acid lyase Scs3p PF10261.4 AET41469.1 - 8e-29 100.3 21.6 3.4e-28 98.2 14.9 2.0 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2207 PF09972.4 AET41469.1 - 0.13 10.7 2.3 0.22 10.0 1.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.3 AET41469.1 - 0.33 10.5 3.4 0.23 11.0 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PAP2 PF01569.16 AET41469.1 - 0.47 10.1 4.3 1 9.0 3.0 1.7 1 0 0 1 1 1 0 PAP2 superfamily CENP-O PF09496.5 AET41470.1 - 3.3e-21 75.3 0.1 6.4e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component HIM1 PF08732.5 AET41471.1 - 2.2e-116 388.7 0.2 2.6e-116 388.4 0.1 1.1 1 0 0 1 1 1 1 HIM1 NDT80_PhoG PF05224.7 AET41472.1 - 3.7e-67 225.9 0.7 3.7e-67 225.9 0.5 2.5 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family PE PF00934.15 AET41472.1 - 0.049 13.7 0.3 0.09 12.8 0.2 1.3 1 0 0 1 1 1 0 PE family GNAT_acetyltr_2 PF13718.1 AET41473.1 - 1.4e-80 269.3 0.0 3.2e-80 268.0 0.0 1.7 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 AET41473.1 - 8.3e-67 224.2 0.2 5e-66 221.6 0.0 2.4 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.6 AET41473.1 - 1.8e-39 133.2 1.0 7.3e-39 131.3 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 AET41473.1 - 4.4e-36 123.0 1.2 1.7e-35 121.1 0.8 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain DEAD PF00270.24 AET41473.1 - 0.0021 17.6 0.0 0.0058 16.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AET41473.1 - 0.0087 16.1 0.0 0.82 9.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain Acetyltransf_7 PF13508.1 AET41473.1 - 0.017 15.2 0.0 0.066 13.3 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_19 PF13245.1 AET41473.1 - 0.046 13.4 0.0 0.65 9.7 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain FumaraseC_C PF10415.4 AET41473.1 - 0.083 12.9 0.0 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Fumarase C C-terminus Tom22 PF04281.8 AET41474.1 - 1.3e-46 157.5 0.9 1.4e-46 157.3 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CDP-OH_P_transf PF01066.16 AET41475.1 - 1.2e-16 60.7 3.0 1.2e-16 60.7 2.1 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase YqzM PF14141.1 AET41475.1 - 1 9.2 5.2 11 5.8 0.8 3.1 2 0 0 2 2 2 0 YqzM-like protein DUF59 PF01883.14 AET41476.1 - 4.1e-05 23.4 0.0 8.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 AAA_17 PF13207.1 AET41477.1 - 8.7e-05 23.3 0.0 0.00016 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AET41477.1 - 0.0016 18.7 0.1 0.022 15.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 AET41477.1 - 0.021 14.3 0.2 0.045 13.3 0.1 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DSPc PF00782.15 AET41478.1 - 6.8e-11 41.8 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AET41478.1 - 0.0096 15.2 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AET41478.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 AET41478.1 - 0.02 15.1 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family AD PF09793.4 AET41479.1 - 2.8e-24 84.7 0.2 4.7e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Anticodon-binding domain GCR PF02155.10 AET41479.1 - 0.036 12.7 0.2 0.048 12.3 0.1 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor DUF3402 PF11882.3 AET41480.1 - 8.9e-96 321.4 14.1 2.3e-94 316.7 9.8 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 AET41480.1 - 1.8e-67 227.2 1.8 1.8e-67 227.2 1.2 1.6 2 0 0 2 2 2 1 N1221-like protein Spc97_Spc98 PF04130.8 AET41481.1 - 1.4e-74 251.3 22.3 2.3e-74 250.6 15.5 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Gar1 PF04410.9 AET41482.1 - 6.5e-45 152.3 0.7 6.5e-45 152.3 0.5 2.2 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region MutS_V PF00488.16 AET41483.1 - 1.3e-78 263.6 0.0 2.3e-78 262.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AET41483.1 - 4.6e-34 118.0 3.3 9.9e-34 116.9 2.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AET41483.1 - 1.6e-27 95.7 0.1 4.7e-27 94.2 0.1 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 AET41483.1 - 1.6e-08 34.6 0.3 7.7e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 MutS domain II AAA_14 PF13173.1 AET41483.1 - 0.0019 18.0 1.8 0.077 12.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain N-SET PF11764.3 AET41484.1 - 2.9e-47 160.6 5.2 2.9e-47 160.6 3.6 3.0 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 AET41484.1 - 2.8e-25 89.5 1.1 5.1e-24 85.4 0.1 3.1 2 1 0 2 2 2 1 SET domain SET_assoc PF11767.3 AET41484.1 - 2.5e-20 71.5 0.2 6.2e-20 70.2 0.2 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated CENP-X PF09415.5 AET41484.1 - 0.019 14.7 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 CENP-S associating Centromere protein X ORC6 PF05460.8 AET41485.1 - 2.5e-96 322.8 0.9 3.1e-96 322.5 0.6 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) XAP5 PF04921.9 AET41485.1 - 0.0077 15.8 2.6 0.21 11.1 0.1 2.2 2 0 0 2 2 2 2 XAP5, circadian clock regulator PDZ_1 PF12812.2 AET41486.1 - 4.4e-52 173.8 0.3 1.4e-35 120.9 0.0 3.2 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 AET41486.1 - 2.2e-13 49.9 1.0 7e-06 25.8 0.0 3.9 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.19 AET41486.1 - 3.1e-11 43.3 0.1 1.4e-06 28.3 0.0 4.1 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Trypsin_2 PF13365.1 AET41486.1 - 6.1e-11 42.3 0.2 5.3e-10 39.3 0.0 2.4 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 AET41486.1 - 7.6e-05 22.3 0.0 0.00088 18.9 0.0 2.4 2 0 0 2 2 2 1 Trypsin Tricorn_PDZ PF14685.1 AET41486.1 - 0.00034 20.3 0.7 0.024 14.4 0.1 3.0 3 0 0 3 3 3 1 Tricorn protease PDZ domain DUF31 PF01732.11 AET41486.1 - 0.012 15.0 0.3 0.02 14.2 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 AET41486.1 - 0.038 13.3 0.2 0.1 12.0 0.1 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Ribosomal_L35p PF01632.14 AET41487.1 - 1.7e-10 40.6 2.6 2.2e-10 40.2 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 TPR_11 PF13414.1 AET41489.1 - 1.8e-39 133.2 20.6 1.2e-13 50.5 0.0 6.8 3 2 3 7 7 7 7 TPR repeat TPR_2 PF07719.12 AET41489.1 - 8.3e-25 84.6 31.6 0.001 18.8 0.0 11.5 11 1 1 12 12 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 AET41489.1 - 2.2e-24 84.0 29.8 1.4e-06 27.6 0.3 11.2 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 AET41489.1 - 8e-23 80.5 11.5 1.2e-07 32.1 0.5 6.7 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 AET41489.1 - 1e-18 65.8 9.0 0.0033 17.5 0.0 7.8 7 2 1 8 8 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 AET41489.1 - 1.1e-17 63.6 20.2 0.0019 18.1 0.3 8.1 3 1 6 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 AET41489.1 - 1.2e-16 60.8 17.8 4.9e-07 29.9 2.0 7.3 6 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 AET41489.1 - 6.1e-16 56.9 27.4 0.00049 19.6 0.2 9.9 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 AET41489.1 - 8.7e-16 56.9 16.2 0.00035 20.9 0.0 8.9 5 3 4 9 9 8 3 Tetratricopeptide repeat Apc3 PF12895.2 AET41489.1 - 2.2e-07 30.9 15.8 0.013 15.5 0.4 5.3 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AET41489.1 - 7e-07 29.3 21.0 0.12 12.9 0.2 9.0 9 0 0 9 9 8 2 Tetratricopeptide repeat DUF3808 PF10300.4 AET41489.1 - 1.5e-05 23.8 2.6 0.078 11.5 0.0 3.5 1 1 2 3 3 3 2 Protein of unknown function (DUF3808) TPR_9 PF13371.1 AET41489.1 - 2.4e-05 24.0 2.2 1.8 8.5 0.0 5.5 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 AET41489.1 - 0.00071 19.1 12.5 4.1 7.4 0.2 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 AET41489.1 - 0.055 13.5 8.7 0.077 13.1 1.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.1 AET41489.1 - 0.35 10.8 3.9 66 3.5 0.0 4.8 6 0 0 6 6 4 0 PPR repeat family Apc5 PF12862.2 AET41489.1 - 1 9.2 5.8 2.8 7.8 0.2 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 SPO22 PF08631.5 AET41489.1 - 1.1 8.2 5.7 3.4 6.6 0.2 3.4 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like Exonuc_VII_S PF02609.11 AET41489.1 - 3.4 7.5 12.8 0.091 12.5 0.6 3.8 4 0 0 4 4 3 0 Exonuclease VII small subunit CHCH PF06747.8 AET41490.1 - 3.7e-07 29.8 7.5 5.3e-07 29.3 5.2 1.3 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 AET41490.1 - 5.7e-05 23.1 2.8 8.6e-05 22.6 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) PASTA PF03793.14 AET41490.1 - 0.14 11.8 0.5 0.23 11.1 0.3 1.3 1 0 0 1 1 1 0 PASTA domain DUF2392 PF10288.4 AET41491.1 - 1.8e-30 105.4 0.0 3.2e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) zf-RING_3 PF14369.1 AET41491.1 - 7.8 6.5 7.8 5.1 7.1 2.5 2.7 2 0 0 2 2 2 0 zinc-finger DCP2 PF05026.8 AET41492.1 - 2.5e-32 110.6 0.7 6.9e-32 109.2 0.5 1.8 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 AET41492.1 - 6.2e-13 48.5 0.0 1.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain NMT1 PF09084.6 AET41493.1 - 4.7e-16 59.0 0.0 2.4e-15 56.6 0.0 2.0 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 AET41493.1 - 2.5e-09 36.9 0.0 4.8e-09 35.9 0.0 1.5 2 0 0 2 2 2 1 NMT1-like family Phosphonate-bd PF12974.2 AET41493.1 - 5e-05 22.8 0.0 6.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 AET41493.1 - 8.5e-05 21.9 0.0 0.00018 20.8 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 LysR_substrate PF03466.15 AET41493.1 - 0.00023 20.3 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain CENP-F_C_Rb_bdg PF10490.4 AET41493.1 - 0.052 12.8 0.2 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 VTC PF09359.5 AET41494.1 - 5.1e-103 343.9 0.1 8.3e-103 343.2 0.1 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 AET41494.1 - 4.4e-21 75.8 14.0 1.3e-10 41.5 0.9 3.7 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 AET41494.1 - 2.1e-07 31.0 6.2 6e-07 29.5 4.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Mad3_BUB1_I PF08311.7 AET41495.1 - 3.5e-43 146.3 1.3 8.5e-43 145.1 0.9 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 AET41495.1 - 1.2e-30 105.2 0.3 1.7e-29 101.4 0.0 2.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.20 AET41495.1 - 1.7e-20 73.2 0.0 2.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41495.1 - 0.00073 18.6 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase LcrV PF04792.7 AET41495.1 - 0.02 13.9 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 V antigen (LcrV) protein Kinase-like PF14531.1 AET41495.1 - 0.024 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like UPF0180 PF03698.8 AET41495.1 - 0.025 14.4 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Pox_A_type_inc PF04508.7 AET41495.1 - 0.03 14.0 1.4 19 5.4 0.1 3.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Cpn60_TCP1 PF00118.19 AET41496.1 - 1.3e-152 508.8 0.4 1.5e-152 508.6 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sad1_UNC PF07738.8 AET41499.1 - 5.9e-09 35.8 0.1 3.6e-08 33.2 0.0 2.3 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1664 PF07889.7 AET41499.1 - 0.0071 16.1 5.4 0.026 14.3 1.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 AET41499.1 - 0.0086 15.8 2.0 0.0086 15.8 1.4 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.3 AET41499.1 - 0.21 11.6 10.8 0.04 13.9 2.9 2.4 2 0 0 2 2 2 0 YlqD protein Sds3 PF08598.6 AET41499.1 - 0.32 10.4 13.2 0.066 12.7 5.8 2.1 2 1 0 2 2 2 0 Sds3-like DUF342 PF03961.8 AET41499.1 - 1.1 7.5 6.2 0.16 10.3 1.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) IncA PF04156.9 AET41499.1 - 3.6 7.1 8.5 0.41 10.2 1.9 2.0 2 0 0 2 2 2 0 IncA protein Bot1p PF12298.3 AET41500.1 - 1.9e-53 180.9 5.1 1.9e-53 180.9 3.6 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Trs65 PF12735.2 AET41501.1 - 1.9e-36 125.9 10.7 2.2e-36 125.7 5.7 2.2 2 1 0 2 2 2 1 TRAPP trafficking subunit Trs65 Clathrin_lg_ch PF01086.12 AET41502.1 - 4.9e-43 147.6 15.1 5.4e-43 147.5 10.5 1.0 1 0 0 1 1 1 1 Clathrin light chain Lsr2 PF11774.3 AET41502.1 - 0.055 13.3 1.2 0.055 13.3 0.9 1.8 2 0 0 2 2 2 0 Lsr2 Urm1 PF09138.6 AET41502.1 - 0.069 13.2 0.3 0.15 12.1 0.1 1.7 1 1 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Malate_synthase PF01274.17 AET41502.1 - 0.12 10.4 3.6 0.26 9.2 2.5 1.5 1 1 0 1 1 1 0 Malate synthase MAP7 PF05672.6 AET41502.1 - 1.1 8.6 17.5 1.5 8.2 12.1 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family SH3_2 PF07653.12 AET41504.1 - 8e-08 31.6 1.2 2.9e-07 29.8 0.1 2.6 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.23 AET41504.1 - 4e-07 29.3 0.1 1.2e-06 27.8 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AET41504.1 - 2.5e-06 26.9 0.0 6.3e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PseudoU_synth_2 PF00849.17 AET41505.1 - 9.4e-30 103.5 0.0 1.5e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF3419 PF11899.3 AET41506.1 - 1.8e-134 448.2 0.0 2.4e-134 447.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_11 PF08241.7 AET41506.1 - 5.5e-11 42.8 0.0 1e-09 38.7 0.0 2.9 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.13 AET41506.1 - 7.3e-10 38.3 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 AET41506.1 - 1.4e-09 38.3 0.0 1.3e-07 32.0 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AET41506.1 - 3.1e-09 36.5 0.0 7.6e-08 32.0 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AET41506.1 - 5.9e-09 35.8 0.0 6.2e-08 32.5 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 AET41506.1 - 2.2e-07 31.4 0.0 6.3e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AET41506.1 - 2.9e-05 24.0 0.0 0.0014 18.6 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 AET41506.1 - 0.0062 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Yqai PF09466.5 AET41506.1 - 0.091 12.7 0.1 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Hypothetical protein Yqai Zip PF02535.17 AET41507.1 - 0.24 10.3 2.9 0.32 9.9 2.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FSH1 PF03959.8 AET41508.1 - 4.9e-59 199.3 0.0 5.6e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AET41508.1 - 4.5e-05 23.4 0.0 0.0091 15.8 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AET41508.1 - 0.0026 17.2 0.6 0.24 10.8 0.4 2.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AET41508.1 - 0.0056 16.4 0.0 0.0091 15.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family dCMP_cyt_deam_1 PF00383.17 AET41509.1 - 3e-21 74.9 0.4 4.5e-21 74.4 0.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 AET41509.1 - 0.034 14.0 0.7 0.14 12.0 0.1 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase MafB19-deam PF14437.1 AET41509.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase PX PF00787.19 AET41510.1 - 2.5e-23 82.0 0.4 6.9e-23 80.6 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 AET41510.1 - 5.5e-07 29.0 17.6 0.00098 18.4 6.1 2.4 1 1 0 2 2 2 2 Vps5 C terminal like Tropomyosin_1 PF12718.2 AET41510.1 - 0.0022 17.8 1.2 0.0022 17.8 0.8 2.5 1 1 1 2 2 2 1 Tropomyosin like APC2 PF08672.6 AET41510.1 - 0.04 14.1 0.9 11 6.3 0.1 3.2 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 Baculo_PEP_C PF04513.7 AET41510.1 - 0.047 13.5 0.9 0.33 10.7 0.0 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 AET41510.1 - 0.049 13.8 2.6 6.6 7.0 0.1 3.2 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 AET41510.1 - 0.21 11.3 6.6 4.1 7.1 0.8 2.6 2 1 0 2 2 2 0 Laminin Domain II DUF1877 PF08974.5 AET41510.1 - 0.24 11.0 6.7 3.2 7.3 0.0 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF1877) FlaC_arch PF05377.6 AET41510.1 - 0.27 11.1 5.0 12 5.8 0.2 3.3 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.1 AET41510.1 - 0.39 10.0 15.3 0.14 11.4 4.4 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4618) Cytochrom_B562 PF07361.6 AET41510.1 - 0.39 11.1 7.1 1.2 9.5 0.0 3.7 2 2 1 3 3 3 0 Cytochrome b562 BAR PF03114.13 AET41510.1 - 2.3 7.6 17.9 5.2 6.5 11.5 2.1 1 1 1 2 2 2 0 BAR domain LOH1CR12 PF10158.4 AET41510.1 - 3.4 7.4 9.6 9.4 6.0 0.1 3.7 3 1 1 4 4 4 0 Tumour suppressor protein DPPIV_N PF00930.16 AET41511.1 - 1.5e-95 319.8 3.4 1.9e-95 319.4 2.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 AET41511.1 - 5.6e-54 182.5 1.1 9.9e-54 181.7 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AET41511.1 - 5.3e-08 32.7 0.1 1.4e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AET41511.1 - 0.0013 18.6 0.0 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AET41511.1 - 0.0062 16.0 0.5 2.9 7.2 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PC_rep PF01851.17 AET41512.1 - 1.3e-25 88.1 13.9 6.6e-07 29.2 0.1 8.9 8 0 0 8 8 8 6 Proteasome/cyclosome repeat ATP-synt_C PF00137.16 AET41513.1 - 1.6e-25 88.7 34.1 4.1e-18 65.0 4.9 2.4 3 0 0 3 3 3 2 ATP synthase subunit C GHMP_kinases_N PF00288.21 AET41514.1 - 3.9e-12 46.0 0.0 8.2e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AET41514.1 - 2.3e-05 24.5 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16_C PF05193.16 AET41515.1 - 8e-39 133.2 0.1 2.4e-38 131.6 0.0 1.8 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AET41515.1 - 3.6e-35 120.9 0.3 1.5e-33 115.7 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Myosin_head PF00063.16 AET41516.1 - 3.4e-243 808.7 17.3 3.4e-243 808.7 12.0 4.0 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 AET41516.1 - 0.015 14.9 0.9 0.1 12.2 0.6 2.3 1 1 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 AET41516.1 - 0.33 10.7 0.0 1.1 9.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain F-box-like PF12937.2 AET41517.1 - 7.7e-08 31.9 0.3 4.4e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AET41517.1 - 0.00023 20.7 0.0 0.00085 18.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 AET41517.1 - 0.014 15.3 0.4 0.083 12.8 0.0 2.5 3 0 0 3 3 3 0 PRANC domain LRR_8 PF13855.1 AET41517.1 - 0.2 11.4 8.5 0.59 9.9 0.1 3.7 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 AET41517.1 - 1 9.0 8.6 5.9 6.6 0.2 4.1 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Ras PF00071.17 AET41518.1 - 1.3e-23 83.1 0.1 8e-18 64.3 0.1 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 AET41518.1 - 1.6e-11 44.7 0.0 1.1e-10 42.0 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 AET41518.1 - 0.0013 18.2 0.0 0.0089 15.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 AET41518.1 - 0.0069 15.6 0.0 3.8 6.7 0.0 2.5 2 1 1 3 3 3 2 ADP-ribosylation factor family SRPRB PF09439.5 AET41518.1 - 0.011 14.9 0.3 0.18 11.0 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF3824 PF12868.2 AET41518.1 - 0.65 10.9 6.3 1.2 10.0 4.4 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_S27e PF01667.12 AET41519.1 - 2e-30 104.0 2.7 2.9e-30 103.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 AET41519.1 - 1.8e-05 24.5 0.7 2.2e-05 24.2 0.5 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 AET41519.1 - 0.052 12.8 3.8 0.074 12.3 2.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 AET41519.1 - 0.12 11.9 1.3 6.2 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AET41519.1 - 0.13 11.9 1.3 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rsm22 PF09243.5 AET41520.1 - 4e-30 104.7 0.3 7e-14 51.5 0.5 3.8 2 2 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 AET41520.1 - 0.0029 17.3 0.0 0.0086 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain SRPRB PF09439.5 AET41521.1 - 1.5e-62 210.0 0.0 1.9e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 AET41521.1 - 4.7e-08 32.4 0.0 6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AET41521.1 - 5.4e-06 25.7 0.0 7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AET41521.1 - 8.7e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AET41521.1 - 0.0002 21.8 0.0 0.00058 20.3 0.0 1.8 1 1 1 2 2 2 1 Miro-like protein AAA_21 PF13304.1 AET41521.1 - 0.054 13.4 0.4 0.12 12.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AET41521.1 - 0.27 10.8 1.5 0.6 9.6 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DPM2 PF07297.7 AET41522.1 - 8.5e-13 48.3 2.8 9.5e-13 48.2 1.9 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Oxidored_q4 PF00507.14 AET41522.1 - 0.028 14.2 3.9 0.035 13.9 2.7 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 PIG-P PF08510.7 AET41522.1 - 0.038 13.6 5.8 0.04 13.5 4.0 1.0 1 0 0 1 1 1 0 PIG-P DUF4229 PF14012.1 AET41522.1 - 1 9.2 8.5 2.7 7.9 5.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) DUF3414 PF11894.3 AET41523.1 - 0 1541.9 51.9 0 1541.7 36.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF1344 PF07076.6 AET41523.1 - 0.011 15.3 0.1 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Nsp1_C PF05064.8 AET41524.1 - 1.2e-38 131.3 6.6 1.2e-38 131.3 4.6 2.2 1 1 1 2 2 2 1 Nsp1-like C-terminal region EzrA PF06160.7 AET41524.1 - 0.0026 16.0 8.7 0.0035 15.5 6.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Muted PF14942.1 AET41524.1 - 0.05 13.4 5.0 0.054 13.3 2.7 1.6 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Caudo_TAP PF02413.12 AET41524.1 - 0.074 13.2 1.7 0.59 10.3 0.7 2.5 2 1 0 2 2 2 0 Caudovirales tail fibre assembly protein LRR_4 PF12799.2 AET41525.1 - 9.6e-05 21.9 11.9 0.19 11.4 0.0 5.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AET41525.1 - 0.00063 19.5 4.0 4 7.8 0.1 5.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 AET41525.1 - 0.066 13.4 1.8 2.8 8.5 0.2 4.5 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 AET41525.1 - 2 8.7 10.0 2.5 8.4 0.2 5.3 4 1 1 5 5 5 0 Leucine Rich Repeat SPOB_ab PF14682.1 AET41526.1 - 0.076 12.8 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal RabGAP-TBC PF00566.13 AET41527.1 - 1.4e-21 76.9 4.9 1.7e-21 76.6 2.1 1.9 1 1 1 2 2 2 1 Rab-GTPase-TBC domain His_Phos_1 PF00300.17 AET41528.1 - 4.6e-42 143.7 0.0 6.2e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Carb_kinase PF01256.12 AET41529.1 - 8.9e-53 179.0 0.1 1.1e-52 178.7 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 AET41529.1 - 0.0003 20.0 0.3 0.0021 17.2 0.0 2.2 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase NAD_binding_1 PF00175.16 AET41530.1 - 7.9e-27 93.9 0.0 2e-26 92.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AET41530.1 - 3e-23 81.7 0.0 5e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AET41530.1 - 2e-06 27.7 0.0 0.00078 19.3 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain SLT_L PF14718.1 AET41530.1 - 0.0075 16.0 1.1 0.014 15.1 0.4 1.7 1 1 1 2 2 2 1 Soluble lytic murein transglycosylase L domain HoxA13_N PF12284.3 AET41530.1 - 0.034 14.3 0.3 0.062 13.4 0.2 1.3 1 0 0 1 1 1 0 Hox protein A13 N terminal FAD_binding_2 PF00890.19 AET41531.1 - 1.6e-122 409.3 4.4 2.1e-122 408.9 3.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 AET41531.1 - 9.3e-46 154.8 0.1 1.4e-45 154.2 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.17 AET41531.1 - 6.7e-06 25.2 0.6 0.00063 18.7 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 AET41531.1 - 7.3e-06 25.2 0.0 0.00092 18.3 0.0 2.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 AET41531.1 - 8e-05 22.5 4.3 0.00045 20.1 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AET41531.1 - 0.00014 20.9 2.8 0.0072 15.2 1.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AET41531.1 - 0.0035 16.4 0.3 0.0076 15.3 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 AET41531.1 - 0.077 11.4 1.7 0.15 10.4 0.4 2.0 3 0 0 3 3 3 0 HI0933-like protein Aa_trans PF01490.13 AET41532.1 - 8.3e-90 301.1 29.0 9.9e-90 300.9 20.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.24 AET41533.1 - 2.1e-40 137.9 0.1 4.6e-40 136.8 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AET41533.1 - 5.5e-06 26.5 0.0 0.00091 19.3 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_5 PF07728.9 AET41533.1 - 2.5e-05 24.0 0.0 0.00011 21.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AET41533.1 - 0.0001 22.3 0.0 0.00033 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 AET41533.1 - 0.00033 20.6 0.0 0.00066 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 AET41533.1 - 0.0009 18.2 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 AET41533.1 - 0.0012 19.6 0.0 0.0037 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AET41533.1 - 0.0045 16.7 0.1 0.0093 15.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 AET41533.1 - 0.0051 15.8 0.0 0.0092 15.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AET41533.1 - 0.0093 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AET41533.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 AET41533.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AET41533.1 - 0.025 14.3 0.3 4.3 6.9 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_14 PF13173.1 AET41533.1 - 0.025 14.4 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AET41533.1 - 0.025 14.8 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AET41533.1 - 0.029 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 AET41533.1 - 0.031 14.4 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 AET41533.1 - 0.036 13.6 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 AET41533.1 - 0.037 13.1 0.0 0.096 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 AET41533.1 - 0.04 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 AET41533.1 - 0.047 12.3 0.0 0.077 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 AET41533.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_Rbc25 PF08292.7 AET41534.1 - 7.3e-43 145.6 0.1 1e-42 145.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 AET41534.1 - 7.9e-21 73.9 0.0 2.4e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 YbaJ PF10757.4 AET41534.1 - 0.042 13.9 0.0 5.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Biofilm formation regulator YbaJ LTV PF04180.9 AET41535.1 - 1.2e-114 384.1 29.0 1.4e-114 383.8 20.1 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF3294 PF07957.6 AET41536.1 - 3.4e-84 281.6 1.9 3.8e-84 281.5 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Snf7 PF03357.16 AET41536.1 - 0.0096 15.3 0.3 0.0096 15.3 0.2 2.2 2 0 0 2 2 2 1 Snf7 CENP-Q PF13094.1 AET41536.1 - 0.044 13.8 2.5 0.15 12.0 1.7 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit BRE1 PF08647.6 AET41536.1 - 2.3 8.2 7.7 2.6 8.0 1.2 2.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Ribosomal_L29 PF00831.18 AET41536.1 - 6.1 6.6 7.5 21 4.8 0.1 3.5 3 1 0 3 3 3 0 Ribosomal L29 protein PUF PF00806.14 AET41537.1 - 1.3e-31 106.2 11.0 0.0003 20.0 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Cpn60_TCP1 PF00118.19 AET41538.1 - 3e-134 448.2 4.2 3.5e-134 448.0 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 AET41538.1 - 0.055 13.5 0.1 0.83 9.7 0.0 2.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Vps53_N PF04100.7 AET41539.1 - 9.7e-83 278.0 9.4 9.7e-83 278.0 6.5 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF3724 PF12521.3 AET41539.1 - 0.15 11.8 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) ArdA PF07275.6 AET41539.1 - 0.24 11.6 5.2 6.3 7.0 0.1 3.5 3 1 0 4 4 4 0 Antirestriction protein (ArdA) HORMA PF02301.13 AET41540.1 - 2.2e-47 161.2 0.1 2.5e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 AET41540.1 - 0.00015 21.2 0.0 0.00021 20.8 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 13 V-set_CD47 PF08204.6 AET41540.1 - 0.0096 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain SspB PF04386.8 AET41540.1 - 0.013 15.0 0.2 0.09 12.3 0.0 2.1 1 1 0 2 2 2 0 Stringent starvation protein B DUF1649 PF07855.7 AET41540.1 - 0.041 13.5 0.7 1.4 8.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1649) DUF4279 PF14106.1 AET41540.1 - 0.1 12.4 0.1 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) DUF3440 PF11922.3 AET41540.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) RBD-FIP PF09457.5 AET41540.1 - 1.4 8.7 5.4 0.17 11.7 0.4 1.9 2 0 0 2 2 2 0 FIP domain PPTA PF01239.17 AET41541.1 - 7.4e-39 129.5 14.7 5e-09 35.1 0.0 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Cyclin_N PF00134.18 AET41542.1 - 2.8e-15 55.9 6.5 4.2e-15 55.4 2.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 AET41542.1 - 0.092 12.5 0.1 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DEAD PF00270.24 AET41543.1 - 7.3e-44 149.2 0.1 2.2e-43 147.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AET41543.1 - 8.2e-25 86.1 0.3 1.7e-24 85.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AET41543.1 - 9.6e-21 73.4 0.0 2.4e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 AET41543.1 - 0.00013 21.9 0.0 0.00043 20.2 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain FHA PF00498.21 AET41544.1 - 1e-15 57.5 0.0 8.2e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 FHA domain HSP70 PF00012.15 AET41545.1 - 3.8e-264 877.1 10.7 4.4e-264 876.9 7.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AET41545.1 - 2.4e-18 65.8 1.4 5.8e-17 61.2 0.1 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 AET41545.1 - 0.0035 16.5 4.7 0.079 12.0 0.1 3.2 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Radial_spoke_3 PF06098.6 AET41545.1 - 0.0076 15.2 2.9 0.016 14.2 2.0 1.4 1 0 0 1 1 1 1 Radial spoke protein 3 FtsA PF14450.1 AET41545.1 - 0.028 14.2 4.9 0.43 10.4 0.7 3.5 2 2 0 2 2 2 0 Cell division protein FtsA Nramp PF01566.13 AET41546.1 - 1.9e-91 306.5 17.5 2.5e-91 306.1 12.1 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Mpv17_PMP22 PF04117.7 AET41546.1 - 0.7 9.5 7.0 0.69 9.5 1.1 2.6 2 0 0 2 2 2 0 Mpv17 / PMP22 family RNase_PH PF01138.16 AET41548.1 - 6.9e-29 100.8 0.0 9.4e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AET41548.1 - 2.4e-07 30.5 0.2 8.1e-07 28.8 0.1 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.8 AET41549.1 - 3.8e-78 262.7 30.0 3.8e-78 262.7 20.8 1.7 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 AET41549.1 - 1.4e-08 34.5 7.6 1.4e-08 34.5 5.3 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) PIG-U PF06728.8 AET41549.1 - 2.9e-06 26.3 33.7 1.6e-05 23.9 23.0 2.1 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U CBF PF03914.12 AET41552.1 - 5.3e-37 126.8 1.0 1.8e-36 125.0 0.4 2.1 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 AET41552.1 - 2.2e-32 111.1 1.8 2.2e-32 111.1 1.3 2.6 2 1 0 2 2 2 1 Nucleolar complex-associated protein Prismane PF03063.15 AET41552.1 - 1 7.6 3.0 1.1 7.5 1.1 1.7 1 1 1 2 2 2 0 Prismane/CO dehydrogenase family 60KD_IMP PF02096.15 AET41552.1 - 2.2 7.8 5.2 6.3 6.3 3.6 1.8 1 1 0 1 1 1 0 60Kd inner membrane protein AAA_11 PF13086.1 AET41552.1 - 3 7.3 8.4 0.48 9.9 2.1 2.1 2 0 0 2 2 2 0 AAA domain Mpp10 PF04006.7 AET41553.1 - 7.1e-123 411.0 65.0 8.8e-123 410.7 45.0 1.0 1 0 0 1 1 1 1 Mpp10 protein Peptidase_C13 PF01650.13 AET41553.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase C13 family Aa_trans PF01490.13 AET41554.1 - 1.6e-76 257.4 27.1 1.9e-76 257.2 18.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fasciclin PF02469.17 AET41555.1 - 8.2e-26 90.5 0.1 4e-05 23.6 0.0 5.8 5 1 0 5 5 5 5 Fasciclin domain Dynamin_M PF01031.15 AET41556.1 - 6.3e-111 369.8 0.0 9.5e-111 369.2 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 AET41556.1 - 1.9e-53 180.7 0.0 1.9e-53 180.7 0.0 2.9 3 1 0 3 3 3 1 Dynamin family GED PF02212.13 AET41556.1 - 1.8e-29 101.4 0.9 6.1e-29 99.7 0.6 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AET41556.1 - 0.0003 20.7 0.4 0.007 16.3 0.3 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AET41556.1 - 0.012 16.1 0.1 0.084 13.3 0.0 2.4 2 1 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 AET41556.1 - 0.059 13.3 0.2 0.059 13.3 0.2 2.4 3 0 0 3 3 3 0 AAA domain zf-CCHC_4 PF14392.1 AET41556.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle BSMAP PF12280.3 AET41556.1 - 0.12 12.2 0.4 0.24 11.2 0.3 1.4 1 0 0 1 1 1 0 Brain specific membrane anchored protein KAT11 PF08214.6 AET41557.1 - 6e-90 301.8 0.9 7.2e-90 301.5 0.6 1.1 1 0 0 1 1 1 1 Histone acetylation protein Proteasome PF00227.21 AET41558.1 - 1.3e-46 158.2 0.7 1.5e-46 158.0 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1 PF08457.5 AET41559.1 - 1.3e-35 122.8 69.1 2e-34 118.9 44.3 2.8 1 1 1 2 2 2 2 Sfi1 spindle body protein Sfi1_C PF10638.4 AET41559.1 - 1.3e-33 115.6 1.5 4.2e-33 114.0 1.0 2.0 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Ribophorin_I PF04597.9 AET41560.1 - 2e-126 422.0 6.1 2.2e-126 421.8 4.2 1.0 1 0 0 1 1 1 1 Ribophorin I ORC3_N PF07034.6 AET41561.1 - 5.2e-06 25.6 0.6 1.6e-05 24.0 0.6 1.6 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus COX16 PF14138.1 AET41562.1 - 1.5e-30 105.1 0.2 2.2e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF221 PF02714.10 AET41563.1 - 4.9e-89 298.4 24.6 4.9e-89 298.4 17.0 2.4 4 0 0 4 4 4 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AET41563.1 - 3e-28 98.3 2.3 3e-28 98.3 1.6 2.9 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AET41563.1 - 6.8e-08 32.2 0.0 1.7e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF2404 PF10296.4 AET41564.1 - 1.5e-05 24.9 0.0 5.9e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) SYS1 PF09801.4 AET41565.1 - 9.4e-48 161.8 13.8 1.1e-47 161.6 9.6 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Oxidored_q2 PF00420.19 AET41565.1 - 3.2 7.4 8.2 2.4 7.7 1.7 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PP2C PF00481.16 AET41566.1 - 1.3e-46 159.0 0.2 2.5e-46 158.1 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 AET41566.1 - 4.2e-39 132.1 82.1 1.1e-10 41.0 3.1 10.7 7 1 4 11 11 11 8 Leucine rich repeat LRR_4 PF12799.2 AET41566.1 - 1.4e-35 120.3 100.2 1.6e-07 30.8 2.2 13.5 5 3 10 16 16 16 12 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.15 AET41566.1 - 1.4e-25 89.7 0.0 3.1e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 AET41566.1 - 3.4e-11 41.5 86.6 0.075 13.1 0.2 19.0 19 1 0 19 19 19 9 Leucine Rich Repeat RA PF00788.18 AET41566.1 - 5.9e-09 36.3 0.0 1.3e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 AET41566.1 - 0.0023 17.8 64.4 0.78 10.2 0.4 15.0 16 1 0 16 16 16 5 Leucine rich repeat LRR_9 PF14580.1 AET41566.1 - 0.041 13.4 20.4 0.12 11.9 2.3 4.4 2 1 2 4 4 4 0 Leucine-rich repeat COX17 PF05051.8 AET41567.1 - 5.4e-20 71.1 7.5 6.2e-20 70.9 5.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 AET41567.1 - 0.00097 18.9 2.3 0.0013 18.6 1.6 1.3 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 AET41567.1 - 0.043 13.9 4.5 0.072 13.2 3.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1903) Cmc1 PF08583.5 AET41567.1 - 0.087 12.6 4.9 0.097 12.4 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PNP_UDP_1 PF01048.15 AET41568.1 - 2.5e-33 115.0 0.0 3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Hist_deacetyl PF00850.14 AET41569.1 - 1.2e-61 208.7 0.2 1.2e-61 208.7 0.2 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Peptidase_C14 PF00656.17 AET41570.1 - 8.1e-69 232.0 0.0 1e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain FlgM PF04316.8 AET41570.1 - 0.15 11.9 0.6 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF342 PF03961.8 AET41571.1 - 0.00013 20.5 12.2 0.00013 20.5 8.5 4.1 2 1 2 4 4 4 2 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 AET41571.1 - 0.11 12.3 19.4 0.99 9.2 2.9 4.9 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NUDIX PF00293.23 AET41572.1 - 4e-28 97.7 0.0 5.9e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain SpoU_methylase PF00588.14 AET41573.1 - 3.6e-27 94.9 0.0 7e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 AET41573.1 - 3.9e-14 52.5 0.1 6.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding IGPD PF00475.13 AET41574.1 - 1.3e-59 200.2 1.3 2.1e-59 199.5 0.9 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Mit_ribos_Mrp51 PF11709.3 AET41575.1 - 4.4e-82 275.8 0.4 5.5e-82 275.4 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit AA_permease PF00324.16 AET41576.1 - 1e-110 370.3 42.6 1.2e-110 370.1 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AET41576.1 - 1.3e-36 126.0 42.9 1.6e-36 125.7 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.24 AET41577.1 - 3.1e-46 156.9 0.0 6.7e-45 152.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET41577.1 - 6.5e-26 90.0 0.2 1.4e-25 88.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET41577.1 - 0.0038 17.0 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 AET41577.1 - 0.064 11.6 0.0 0.2 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 AET41577.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit RNA_pol_Rpb2_6 PF00562.23 AET41578.1 - 2.7e-120 401.6 2.4 2.8e-120 401.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AET41578.1 - 2.6e-59 199.5 2.5 4.4e-59 198.8 1.8 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AET41578.1 - 4.2e-40 137.2 5.2 1.1e-39 135.8 3.4 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 AET41578.1 - 8.9e-30 102.7 0.1 3.3e-29 100.9 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 AET41578.1 - 3.6e-27 93.9 1.4 8.7e-27 92.7 0.5 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 AET41578.1 - 7e-19 67.3 0.0 1.7e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 AET41578.1 - 7e-11 41.9 0.3 2.4e-10 40.2 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 AET41578.1 - 0.00078 17.9 1.4 0.0008 17.8 0.1 1.6 2 0 0 2 2 2 1 Baculovirus Y142 protein Mei5 PF10376.4 AET41579.1 - 2.6e-38 131.7 15.3 3.2e-38 131.4 10.6 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein PBP5_C PF07943.8 AET41579.1 - 0.036 14.0 1.0 0.036 14.0 0.7 2.2 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain Lumazine_bd PF12870.2 AET41579.1 - 0.11 12.4 13.5 0.43 10.6 4.8 2.7 2 1 1 3 3 3 0 Lumazine-binding domain Fungal_trans_2 PF11951.3 AET41579.1 - 0.28 9.7 2.0 0.44 9.0 0.1 1.8 1 1 0 2 2 2 0 Fungal specific transcription factor domain BACK PF07707.10 AET41579.1 - 0.34 10.7 6.0 0.2 11.5 2.7 1.7 2 0 0 2 2 2 0 BTB And C-terminal Kelch Atg14 PF10186.4 AET41579.1 - 2.4 7.0 12.7 0.38 9.6 0.4 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Noc2 PF03715.8 AET41580.1 - 6.5e-125 415.9 2.4 6.5e-125 415.9 1.7 2.5 3 0 0 3 3 3 1 Noc2p family MMR_HSR1 PF01926.18 AET41581.1 - 5.5e-09 35.9 0.0 2e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AET41581.1 - 0.0018 17.4 0.1 0.0078 15.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 AET41581.1 - 0.0026 17.0 0.0 0.049 12.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AET41581.1 - 0.0036 17.1 0.0 0.018 14.8 0.0 2.2 3 0 0 3 3 3 1 Dynamin family AAA_33 PF13671.1 AET41581.1 - 0.032 14.1 0.0 0.078 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AET41581.1 - 0.062 13.4 0.1 8.5 6.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.22 AET41581.1 - 0.13 11.7 0.0 1.2 8.5 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain APG6 PF04111.7 AET41582.1 - 5.2e-101 337.8 10.5 6.5e-101 337.5 7.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 AET41582.1 - 0.25 9.1 5.8 0.38 8.5 4.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lge1 PF11488.3 AET41582.1 - 0.7 10.1 8.9 0.16 12.2 3.2 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 NuA4 PF09340.5 AET41582.1 - 7.1 6.3 8.7 0.56 9.8 1.8 2.2 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF972 PF06156.8 AET41582.1 - 9.8 6.5 13.2 3.6 7.9 4.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Ribonuc_red_lgC PF02867.10 AET41583.1 - 2.9e-204 679.6 0.0 3.5e-204 679.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AET41583.1 - 1.8e-23 82.0 0.0 4.6e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AET41583.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 ATP cone domain Ribonuclease_T2 PF00445.13 AET41584.1 - 5.5e-39 133.7 0.0 7.5e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Striatin PF08232.7 AET41585.1 - 0.026 14.8 2.4 0.068 13.4 0.2 2.1 2 0 0 2 2 2 0 Striatin family MCR_gamma PF02240.11 AET41585.1 - 0.12 11.5 0.0 7 5.6 0.0 2.2 2 0 0 2 2 2 0 Methyl-coenzyme M reductase gamma subunit DUF2951 PF11166.3 AET41585.1 - 0.47 10.3 2.7 0.66 9.8 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) CorA PF01544.13 AET41585.1 - 0.5 9.3 3.0 1.1 8.2 2.1 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FlxA PF14282.1 AET41585.1 - 4 7.4 10.9 0.23 11.3 0.1 2.8 2 1 0 2 2 2 0 FlxA-like protein DUF4404 PF14357.1 AET41585.1 - 9.8 6.6 8.2 1.3 9.4 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Y_phosphatase PF00102.22 AET41586.1 - 4.1e-57 193.2 1.3 2e-56 190.9 0.9 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AET41586.1 - 0.0019 18.4 0.0 0.0093 16.2 0.0 2.1 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 AET41586.1 - 0.055 13.0 0.8 0.26 10.8 0.0 2.5 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 AET41586.1 - 0.086 12.8 0.2 0.5 10.4 0.0 2.3 3 0 0 3 3 3 0 Inositol hexakisphosphate IBN_N PF03810.14 AET41587.1 - 1.2e-12 47.5 0.2 5.8e-12 45.3 0.2 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain ACDC PF14733.1 AET41587.1 - 0.0028 17.7 1.2 0.0089 16.1 0.1 2.7 3 0 0 3 3 3 1 AP2-coincident C-terminal HEAT_2 PF13646.1 AET41587.1 - 0.022 15.0 0.0 12 6.2 0.0 3.4 3 1 0 3 3 3 0 HEAT repeats NAPRTase PF04095.11 AET41588.1 - 2e-64 217.1 0.0 2.6e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF4607 PF15380.1 AET41589.1 - 0.097 12.1 0.1 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) WD40 PF00400.27 AET41590.1 - 5.3e-06 26.1 8.7 0.018 14.8 0.1 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat RNA_pol_N PF01194.12 AET41591.1 - 2.5e-29 101.0 0.5 2.9e-29 100.8 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 AET41591.1 - 0.039 14.0 0.2 0.049 13.7 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) YhfH PF14149.1 AET41591.1 - 0.077 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 YhfH-like protein Dynamin_N PF00350.18 AET41592.1 - 8.3e-41 139.6 0.0 2.6e-40 137.9 0.0 2.0 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AET41592.1 - 4.7e-05 22.3 5.9 0.0045 15.8 0.0 3.2 3 0 0 3 3 3 2 Dynamin central region Miro PF08477.8 AET41592.1 - 0.0011 19.4 0.0 0.0031 18.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AET41592.1 - 0.0012 18.7 0.0 0.016 15.1 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AET41592.1 - 0.014 15.3 0.2 0.053 13.5 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain DUF1451 PF07295.6 AET41592.1 - 1.3 8.7 5.3 4.2 7.1 1.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1451) Linker_histone PF00538.14 AET41593.1 - 7.5e-21 74.0 0.1 7.5e-21 74.0 0.1 2.4 1 1 2 3 3 3 1 linker histone H1 and H5 family HC2 PF07382.6 AET41593.1 - 4.5e-06 26.6 49.7 7.9e-06 25.8 34.5 1.4 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Metaviral_G PF09595.5 AET41593.1 - 1.2 8.7 13.6 1.6 8.3 9.4 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein TRF PF08558.5 AET41594.1 - 4.3e-73 245.5 0.0 6.6e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 AET41594.1 - 6.7e-06 26.0 0.2 2.8e-05 24.0 0.2 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AET41594.1 - 0.0037 17.3 0.0 0.0091 16.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Med3 PF11593.3 AET41594.1 - 6.9 5.8 15.2 13 4.9 10.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.27 AET41595.1 - 1.2e-39 132.7 24.8 8.3e-08 31.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat YEATS PF03366.11 AET41596.1 - 4.4e-20 71.1 0.0 8.6e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 YEATS family YEATS PF03366.11 AET41597.1 - 4.4e-25 87.2 0.0 8e-25 86.3 0.0 1.4 1 0 0 1 1 1 1 YEATS family DNA_pol3_tau_4 PF12168.3 AET41597.1 - 0.033 14.5 0.7 0.061 13.7 0.5 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding YqeY PF09424.5 AET41598.1 - 1.3e-22 80.2 3.1 1.7e-22 79.7 2.1 1.1 1 0 0 1 1 1 1 Yqey-like protein SDH_sah PF01972.11 AET41598.1 - 0.012 14.4 1.4 0.014 14.2 0.9 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Cas_DxTHG PF09455.5 AET41598.1 - 0.012 14.7 3.8 0.014 14.5 2.6 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family M11L PF11099.3 AET41598.1 - 0.013 15.2 5.6 0.015 15.0 3.4 1.5 1 1 0 1 1 1 0 Apoptosis regulator M11L like tRNA_NucTran2_2 PF13735.1 AET41598.1 - 0.013 15.2 2.9 0.038 13.8 1.9 1.9 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Pox_A3L PF05288.6 AET41598.1 - 0.32 10.7 2.5 0.26 11.0 0.3 1.9 2 1 0 2 2 2 0 Poxvirus A3L Protein GRAB PF10375.4 AET41599.1 - 1.2e-06 27.9 5.4 2.8e-06 26.7 1.3 2.5 2 0 0 2 2 2 1 GRIP-related Arf-binding domain IncA PF04156.9 AET41599.1 - 8.9e-06 25.4 60.3 4.9e-05 23.0 12.5 3.8 1 1 2 3 3 3 2 IncA protein AAA_13 PF13166.1 AET41599.1 - 0.00011 20.8 30.8 0.00011 20.8 21.3 2.3 1 1 1 2 2 2 1 AAA domain TMF_DNA_bd PF12329.3 AET41599.1 - 0.00068 19.3 9.3 0.00068 19.3 6.4 5.6 2 1 2 5 5 4 1 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 AET41599.1 - 0.002 17.8 35.5 0.039 13.6 6.9 4.8 2 1 3 5 5 5 3 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.6 AET41599.1 - 0.0029 16.3 19.8 0.0029 16.3 13.7 4.1 1 1 3 4 4 4 2 Spc7 kinetochore protein Reo_sigmaC PF04582.7 AET41599.1 - 0.011 14.9 19.3 0.2 10.7 4.7 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 AET41599.1 - 0.06 12.2 49.3 0.0091 14.9 7.4 3.9 1 1 3 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 AET41599.1 - 0.096 12.5 52.8 0.03 14.2 12.0 4.2 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 AET41599.1 - 0.11 9.8 47.1 0.21 8.8 32.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS5 PF14817.1 AET41599.1 - 0.34 9.3 41.3 0.44 9.0 10.6 2.6 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 5 THOC7 PF05615.8 AET41599.1 - 1.2 9.4 51.2 0.038 14.2 8.8 4.1 1 1 3 4 4 4 0 Tho complex subunit 7 M_domain PF12938.2 AET41599.1 - 1.2 8.8 20.9 0.57 9.9 8.4 2.6 2 1 0 2 2 2 0 M domain of GW182 DUF1664 PF07889.7 AET41599.1 - 2.4 7.9 34.8 0.26 11.0 7.6 4.1 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) MbeD_MobD PF04899.7 AET41599.1 - 2.5 8.0 20.0 0.53 10.2 2.5 3.5 3 1 0 3 3 3 0 MbeD/MobD like FliJ PF02050.11 AET41599.1 - 2.5 8.1 50.0 0.46 10.5 8.8 4.4 1 1 3 4 4 4 0 Flagellar FliJ protein SlyX PF04102.7 AET41599.1 - 4.2 7.8 43.5 1.4 9.3 0.3 6.8 1 1 5 6 6 6 0 SlyX CotJB PF12652.2 AET41599.1 - 8.9 6.4 8.0 1.8 8.6 1.3 2.7 2 1 1 3 3 3 0 CotJB protein RFC1 PF08519.7 AET41600.1 - 8.4e-55 184.7 1.0 2e-54 183.5 0.1 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 AET41600.1 - 1.4e-12 47.9 0.0 4e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 AET41600.1 - 1.2e-09 38.1 0.0 3.5e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.1 AET41600.1 - 6.5e-07 29.5 0.0 0.0001 22.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 AET41600.1 - 9.8e-07 27.8 0.2 0.00012 20.9 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 AET41600.1 - 8e-06 26.6 0.4 8.8e-05 23.3 0.0 2.9 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.7 AET41600.1 - 3.5e-05 22.9 0.0 6.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PTCB-BRCT PF12738.2 AET41600.1 - 0.0013 18.4 0.1 0.0076 16.0 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain AAA_33 PF13671.1 AET41600.1 - 0.0016 18.3 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AET41600.1 - 0.0022 18.0 0.0 0.02 14.8 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 AET41600.1 - 0.003 17.7 0.0 0.0092 16.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 AET41600.1 - 0.0039 17.4 0.1 0.014 15.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AET41600.1 - 0.0044 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AET41600.1 - 0.017 14.8 0.1 0.051 13.3 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_5 PF07728.9 AET41600.1 - 0.023 14.4 0.0 0.094 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 AET41600.1 - 0.044 13.4 0.0 0.53 9.9 0.0 2.6 3 0 0 3 3 3 0 NACHT domain DPPIV_N PF00930.16 AET41601.1 - 8.6e-86 287.6 2.7 1.2e-85 287.2 1.9 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 AET41601.1 - 1.1e-46 158.7 0.1 2.1e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AET41601.1 - 6.1e-07 29.2 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AET41601.1 - 6e-05 23.0 0.0 0.0014 18.6 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 AET41601.1 - 0.0018 16.6 0.0 0.037 12.3 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.11 AET41601.1 - 0.089 12.2 0.0 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ribosomal_L18p PF00861.17 AET41602.1 - 1.2e-46 157.7 1.6 3.5e-45 153.0 0.0 2.6 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 AET41602.1 - 9.9e-32 109.3 5.1 9.9e-32 109.3 3.5 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 AET41602.1 - 0.043 13.8 0.2 0.88 9.6 0.0 2.7 3 0 0 3 3 3 0 Threonine synthase N terminus CtaG_Cox11 PF04442.9 AET41604.1 - 2.5e-58 196.1 0.0 4.2e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Zn_clus PF00172.13 AET41605.1 - 7.9e-05 22.4 9.4 0.00017 21.3 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_1 PF00698.16 AET41606.1 - 0.028 13.7 0.0 0.066 12.5 0.0 1.5 1 1 0 1 1 1 0 Acyl transferase domain Mito_carr PF00153.22 AET41607.1 - 5.2e-67 221.6 0.2 2.7e-25 87.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2407_C PF13373.1 AET41608.1 - 1.2e-39 135.4 0.7 1.2e-39 135.4 0.5 1.6 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.4 AET41608.1 - 6.5e-18 64.7 0.0 1.2e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2453 PF10507.4 AET41608.1 - 0.014 15.1 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) Acetyltransf_11 PF13720.1 AET41608.1 - 0.078 13.2 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 RNA_pol_Rpb8 PF03870.10 AET41609.1 - 5.9e-44 149.6 0.0 7.5e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 Ephrin_lbd PF01404.14 AET41609.1 - 0.052 13.3 0.2 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin receptor ligand binding domain Glyco_transf_7N PF13733.1 AET41609.1 - 0.1 11.9 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 ExoD PF06055.7 AET41609.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD NifU_N PF01592.11 AET41610.1 - 1.9e-54 182.9 0.1 2.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain LRR_4 PF12799.2 AET41611.1 - 5.8e-05 22.6 19.5 0.18 11.4 0.4 6.2 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) DUF1691 PF07950.6 AET41612.1 - 0.00076 19.3 0.1 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1691) PHD PF00628.24 AET41613.1 - 3.5e-12 45.8 4.5 3.5e-12 45.8 3.1 3.0 3 0 0 3 3 3 1 PHD-finger WD40 PF00400.27 AET41614.1 - 3.3e-09 36.2 2.8 0.026 14.4 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AET41614.1 - 0.029 14.2 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.20 AET41615.1 - 1.6e-67 227.3 0.0 2.3e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41615.1 - 6.7e-38 130.2 0.0 1.1e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET41615.1 - 3e-08 32.9 0.0 5.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AET41615.1 - 0.0038 16.3 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET41615.1 - 0.018 14.7 0.0 0.13 11.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family GrpE PF01025.14 AET41616.1 - 2.7e-50 170.1 5.4 3.4e-50 169.8 3.7 1.1 1 0 0 1 1 1 1 GrpE UCH_1 PF13423.1 AET41616.1 - 0.046 13.1 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TPD52 PF04201.10 AET41616.1 - 0.1 12.3 4.9 0.17 11.6 3.3 1.4 1 1 0 1 1 1 0 Tumour protein D52 family DUF4559 PF15112.1 AET41616.1 - 0.19 10.8 2.1 0.25 10.4 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) IncA PF04156.9 AET41616.1 - 0.64 9.5 4.6 0.94 9.0 3.2 1.3 1 0 0 1 1 1 0 IncA protein TBCA PF02970.11 AET41616.1 - 3.1 7.9 7.3 3 7.9 3.8 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor A Pkinase PF00069.20 AET41617.1 - 6e-64 215.7 0.0 1.1e-63 214.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41617.1 - 3.9e-37 127.7 0.0 6.7e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AET41617.1 - 2.4e-07 30.0 0.0 4.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AET41617.1 - 0.04 12.9 0.2 0.098 11.7 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AET41617.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L35Ae PF01247.13 AET41618.1 - 1.7e-42 143.1 0.7 1.9e-42 142.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 AET41618.1 - 0.00022 21.0 0.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Ran_BP1 PF00638.13 AET41619.1 - 5.3e-34 116.8 0.4 1.3e-33 115.6 0.3 1.7 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 AET41619.1 - 1.3e-11 44.7 4.1 3e-11 43.5 0.1 3.5 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) AAA PF00004.24 AET41620.1 - 1.1e-37 129.1 0.0 1.8e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AET41620.1 - 1.7e-07 31.1 0.0 4.8e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AET41620.1 - 6.2e-07 29.6 0.4 0.0033 17.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 AET41620.1 - 8.8e-07 29.0 0.1 6.1e-06 26.3 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 AET41620.1 - 2.4e-06 27.3 0.0 1.7e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 AET41620.1 - 6.1e-06 27.0 0.1 1.4e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AET41620.1 - 6.3e-06 25.4 0.0 1.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 AET41620.1 - 1.8e-05 24.8 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_2 PF07724.9 AET41620.1 - 7.2e-05 22.7 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 AET41620.1 - 7.5e-05 22.2 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 AET41620.1 - 0.00029 20.0 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 AET41620.1 - 0.00056 18.9 0.0 0.00086 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 AET41620.1 - 0.00067 19.9 0.0 0.0034 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AET41620.1 - 0.00083 18.5 0.2 0.0022 17.1 0.1 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 AET41620.1 - 0.0009 18.6 0.7 0.064 12.6 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AET41620.1 - 0.0011 18.8 0.0 0.0046 16.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AET41620.1 - 0.0011 19.0 0.0 0.0034 17.5 0.0 2.0 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 AET41620.1 - 0.01 15.8 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 AET41620.1 - 0.01 15.5 0.1 0.034 13.8 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Sigma54_activat PF00158.21 AET41620.1 - 0.016 14.7 0.0 0.054 12.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 AET41620.1 - 0.016 14.8 0.1 0.061 12.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 AET41620.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 AET41620.1 - 0.018 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 AET41620.1 - 0.023 13.4 0.1 0.057 12.1 0.0 1.6 1 1 1 2 2 2 0 TIP49 C-terminus Bac_DnaA PF00308.13 AET41620.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.22 AET41620.1 - 0.034 14.4 0.0 0.072 13.3 0.0 1.9 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.10 AET41620.1 - 0.038 12.6 0.0 0.062 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 AET41620.1 - 0.04 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 AET41620.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 AET41620.1 - 0.044 13.0 0.1 5 6.2 0.0 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 AET41620.1 - 0.065 12.9 0.1 0.86 9.2 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 AET41620.1 - 0.066 12.0 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain tRNA_lig_kinase PF08303.6 AET41620.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain Viral_helicase1 PF01443.13 AET41620.1 - 0.097 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Homez PF11569.3 AET41620.1 - 0.11 11.6 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez AAA_10 PF12846.2 AET41620.1 - 0.11 11.9 0.4 7.8 5.8 0.0 2.5 1 1 1 2 2 2 0 AAA-like domain KAP_NTPase PF07693.9 AET41620.1 - 0.64 8.9 4.2 6.3 5.6 0.0 2.8 3 1 1 4 4 4 0 KAP family P-loop domain Evr1_Alr PF04777.8 AET41621.1 - 1.6e-31 108.0 2.6 1.6e-31 108.0 1.8 1.6 2 0 0 2 2 2 1 Erv1 / Alr family WH2 PF02205.15 AET41622.1 - 2.8e-11 42.6 1.1 2.2e-09 36.6 0.3 2.9 3 0 0 3 3 3 2 WH2 motif Adap_comp_sub PF00928.16 AET41623.1 - 2e-88 295.8 0.5 2.6e-88 295.5 0.3 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AET41623.1 - 4.1e-07 29.8 1.0 7.7e-07 28.9 0.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AhpC-TSA PF00578.16 AET41624.1 - 1.3e-29 102.3 0.1 1.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AET41624.1 - 3.5e-21 75.2 0.0 4.5e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 AET41624.1 - 0.00044 20.1 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF1644 PF07800.7 AET41624.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Corona_NS2A PF05213.7 AET41624.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein DUF2408 PF10303.4 AET41625.1 - 3.8e-69 230.9 9.5 4.2e-43 146.6 0.3 4.9 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Vac_Fusion PF02346.11 AET41625.1 - 7 6.1 7.3 0.74 9.2 0.2 2.9 4 0 0 4 4 4 0 Chordopoxvirus fusion protein WSC PF01822.14 AET41626.1 - 1.1e-09 38.0 13.7 1.1e-09 38.0 9.5 2.2 2 1 0 2 2 2 1 WSC domain DUF1191 PF06697.7 AET41626.1 - 0.0012 17.6 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Podoplanin PF05808.6 AET41626.1 - 0.0013 18.3 6.8 0.0024 17.4 4.7 1.4 1 0 0 1 1 1 1 Podoplanin Yip1 PF04893.12 AET41626.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Yip1 domain EphA2_TM PF14575.1 AET41626.1 - 0.034 14.5 0.0 0.19 12.1 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 AET41626.1 - 0.5 10.0 2.3 0.38 10.4 0.2 1.8 2 0 0 2 2 2 0 Syndecan domain Nitrate_red_gam PF02665.9 AET41626.1 - 0.89 8.8 3.3 1 8.6 0.1 2.3 3 0 0 3 3 3 0 Nitrate reductase gamma subunit SIT PF15330.1 AET41626.1 - 1.4 9.0 5.0 1.4 9.0 0.0 3.1 3 1 1 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT REC114-like PF15165.1 AET41626.1 - 2.4 7.8 5.0 2.1 8.0 2.4 1.7 1 1 0 1 1 1 0 Meiotic recombination protein REC114-like bZIP_1 PF00170.16 AET41627.1 - 1.1e-07 31.6 22.5 0.00041 20.2 10.2 2.5 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 AET41627.1 - 1.1e-05 25.1 2.4 2.2e-05 24.1 1.7 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Tox-ODYAM1 PF15642.1 AET41627.1 - 0.12 11.0 3.6 0.22 10.1 2.5 1.4 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus bZIP_2 PF07716.10 AET41627.1 - 0.77 9.6 22.8 8.7 6.2 3.1 2.8 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 AET41627.1 - 3.4 8.0 14.8 0.84 9.9 6.0 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor DMPK_coil PF08826.5 AET41627.1 - 6 6.8 10.4 5.9 6.8 4.4 2.7 2 0 0 2 2 2 0 DMPK coiled coil domain like Glyco_hydro_72 PF03198.9 AET41628.1 - 1.6e-138 460.9 3.0 2e-138 460.6 2.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 AET41628.1 - 0.00029 20.1 0.0 0.0012 18.1 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GIT_SHD PF08518.6 AET41629.1 - 2e-27 94.1 4.4 1.8e-13 49.5 0.1 3.0 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT LPP PF04728.8 AET41629.1 - 0.00034 20.3 0.1 0.83 9.5 0.1 3.3 1 1 1 2 2 2 2 Lipoprotein leucine-zipper TMF_DNA_bd PF12329.3 AET41629.1 - 0.00077 19.2 6.0 0.00077 19.2 4.2 5.4 4 2 2 6 6 6 1 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 AET41629.1 - 4.6 7.0 18.7 0.14 12.0 2.2 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Ribonucleas_3_3 PF14622.1 AET41630.1 - 5.1e-17 62.0 0.0 8.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 AET41630.1 - 0.074 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III domain DEAD PF00270.24 AET41631.1 - 3.5e-41 140.4 0.6 8.3e-41 139.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AET41631.1 - 2.2e-26 91.4 0.1 1e-25 89.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AET41631.1 - 0.00014 21.7 0.0 0.00014 21.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AET41631.1 - 0.024 14.7 0.6 0.15 12.1 0.4 2.2 1 1 0 1 1 1 0 AAA domain ATP-synt_G PF04718.10 AET41632.1 - 4.2e-26 91.6 0.0 4.9e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit MCM PF00493.18 AET41633.1 - 1.1e-138 461.5 0.0 1.9e-138 460.7 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AET41633.1 - 2.7e-24 85.9 2.4 7.9e-24 84.4 0.5 2.7 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 AET41633.1 - 4.2e-06 26.0 0.0 0.00018 20.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AET41633.1 - 1e-05 25.2 0.0 4e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AET41633.1 - 0.00085 18.9 0.0 0.01 15.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AET41633.1 - 0.088 12.2 0.2 3.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain RICTOR_V PF14668.1 AET41634.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF4231 PF14015.1 AET41634.1 - 0.5 10.3 0.0 0.5 10.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) CAF1A PF12253.3 AET41635.1 - 5.2e-23 80.9 11.3 5.2e-23 80.9 7.8 3.2 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 AET41635.1 - 1.8e-15 56.9 62.0 1.8e-15 56.9 43.0 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 AET41635.1 - 0.0018 16.8 39.3 0.005 15.3 27.2 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Borrelia_P83 PF05262.6 AET41635.1 - 0.75 7.9 30.0 1.2 7.3 20.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Daxx PF03344.10 AET41635.1 - 2.2 6.6 38.8 2.7 6.3 3.3 2.4 2 0 0 2 2 2 0 Daxx Family eIF-6 PF01912.13 AET41637.1 - 2.2e-84 281.5 1.1 2.6e-84 281.2 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family Cys_Met_Meta_PP PF01053.15 AET41638.1 - 8.2e-136 452.3 0.0 9.8e-136 452.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AET41638.1 - 7e-11 41.7 0.0 4.1e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 AET41638.1 - 2.5e-08 33.2 0.0 3.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AET41638.1 - 1.6e-07 30.4 0.1 2.5e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AET41638.1 - 1.5e-06 27.5 0.0 3.4e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 AET41638.1 - 2.7e-05 23.0 0.0 4.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 AET41638.1 - 0.016 13.5 0.4 0.099 10.9 0.3 1.9 1 1 0 1 1 1 0 Methionine gamma-lyase Aconitase PF00330.15 AET41639.1 - 7.6e-179 595.0 0.1 2.3e-178 593.4 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AET41639.1 - 4.2e-47 159.5 0.0 8.8e-47 158.4 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.22 AET41640.1 - 5.5e-42 143.8 0.1 5.9e-41 140.4 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 AET41640.1 - 2.2e-26 92.1 0.8 4e-26 91.3 0.1 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DsbC_N PF10411.4 AET41641.1 - 0.14 11.4 0.0 0.31 10.3 0.0 1.6 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus UQ_con PF00179.21 AET41642.1 - 4.8e-32 110.3 0.0 7.8e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Polysacc_deac_1 PF01522.16 AET41644.1 - 1.8e-24 85.7 0.0 2.8e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase GRIP PF01465.15 AET41645.1 - 1.3e-15 56.5 0.3 3.5e-15 55.2 0.2 1.8 1 0 0 1 1 1 1 GRIP domain SlyX PF04102.7 AET41645.1 - 0.00083 19.6 0.9 0.00083 19.6 0.6 10.7 4 3 6 11 11 11 2 SlyX WXG100 PF06013.7 AET41645.1 - 0.021 14.8 1.5 0.021 14.8 1.0 6.1 5 3 0 5 5 5 0 Proteins of 100 residues with WXG tRNA-synt_2 PF00152.15 AET41646.1 - 4.5e-84 282.0 1.4 7.3e-84 281.3 0.9 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AET41646.1 - 4.1e-06 26.5 0.1 8.5e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AET41646.1 - 0.043 13.0 1.2 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) zf-C2H2 PF00096.21 AET41647.1 - 1.2e-08 34.7 12.2 0.00065 19.8 2.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET41647.1 - 0.00036 20.6 0.2 0.00036 20.6 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 AET41647.1 - 0.0004 20.4 11.5 0.0049 17.0 0.8 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 AET41647.1 - 0.00043 20.4 11.1 0.086 13.2 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AET41647.1 - 0.00081 19.4 6.7 0.073 13.2 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AET41647.1 - 3.2 7.9 6.6 10 6.2 0.7 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF822 PF05687.8 AET41647.1 - 5.2 7.4 7.3 1.8 8.9 3.1 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) CHCH PF06747.8 AET41648.1 - 0.002 17.9 0.6 0.0055 16.5 0.4 1.7 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 AET41648.1 - 0.034 14.1 3.3 0.1 12.6 2.3 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 zf-C2H2 PF00096.21 AET41649.1 - 8.2e-10 38.4 8.0 1.1e-05 25.4 0.1 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET41649.1 - 1.5e-06 28.1 4.8 0.00036 20.6 0.0 4.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AET41649.1 - 0.00012 22.2 0.7 0.00012 22.2 0.5 4.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 AET41649.1 - 0.0049 16.7 1.2 1.3 9.0 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AET41649.1 - 0.007 16.4 0.0 0.007 16.4 0.0 3.9 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AET41649.1 - 0.0099 16.0 0.0 0.0099 16.0 0.0 3.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-BED PF02892.10 AET41649.1 - 1.4 8.7 11.9 0.55 10.0 1.5 2.8 1 1 1 2 2 2 0 BED zinc finger Pkinase PF00069.20 AET41650.1 - 5.8e-50 169.8 0.1 1.7e-49 168.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41650.1 - 2.2e-19 69.5 0.0 5.5e-19 68.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Nucleoporin_FG PF13634.1 AET41652.1 - 4.2e-05 23.7 96.7 0.0037 17.4 27.8 3.8 2 1 1 3 3 3 1 Nucleoporin FG repeat region DUF4600 PF15372.1 AET41652.1 - 0.19 11.9 2.8 1.9 8.7 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF1664 PF07889.7 AET41652.1 - 0.19 11.5 2.6 0.43 10.3 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) XRN_N PF03159.13 AET41653.1 - 6.4e-98 326.8 0.1 1.1e-97 326.0 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Bud13 PF09736.4 AET41654.1 - 4.6e-25 88.5 9.0 3.9e-24 85.5 4.0 2.6 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex SAE2 PF08573.5 AET41655.1 - 1.4 9.6 6.4 1.7e+02 2.9 4.4 3.0 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Mito_carr PF00153.22 AET41656.1 - 2.1e-73 242.1 0.2 1.8e-25 88.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_8 PF13833.1 AET41656.1 - 0.045 13.3 0.3 0.43 10.2 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.1 AET41656.1 - 0.2 11.7 9.2 0.23 11.5 0.3 4.4 4 1 0 4 4 4 0 EF-hand domain pair zf-C2H2 PF00096.21 AET41657.1 - 4.4e-10 39.2 11.9 1.1e-05 25.5 1.4 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET41657.1 - 2e-08 33.9 6.2 0.00041 20.4 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AET41657.1 - 3.5e-06 27.0 9.4 0.06 13.6 0.3 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.2 AET41657.1 - 1.3e-05 25.1 3.7 0.0041 17.2 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.10 AET41657.1 - 0.0051 16.5 7.0 0.29 10.9 1.4 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 AET41657.1 - 0.099 12.5 1.2 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 AET41657.1 - 0.12 12.4 2.4 0.23 11.5 1.7 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 AET41657.1 - 0.12 12.7 0.6 0.23 11.8 0.4 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger DUF2256 PF10013.4 AET41657.1 - 0.26 11.0 0.1 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_5 PF13909.1 AET41657.1 - 4.6 7.6 10.1 1.4 9.2 1.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 AET41658.1 - 3.4e-08 33.3 18.7 5.2e-05 23.3 2.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET41658.1 - 3.4e-07 30.2 10.5 7.7e-06 25.9 0.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET41658.1 - 1.1e-06 28.5 14.4 0.00037 20.6 1.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 AET41658.1 - 0.0046 17.1 1.4 0.0046 17.1 0.9 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type C1_4 PF07975.7 AET41658.1 - 0.04 13.9 2.2 0.04 13.9 1.5 2.0 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.1 AET41658.1 - 0.35 10.8 5.5 1.6 8.7 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AET41659.1 - 1.7e-06 28.0 8.1 0.0025 18.0 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AET41659.1 - 1.3e-05 25.2 12.9 0.00055 20.1 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 AET41659.1 - 1.9e-05 24.6 5.7 0.024 14.9 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger FMN_red PF03358.10 AET41660.1 - 2.5e-06 27.0 0.0 4.3e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 AET41660.1 - 3.7e-06 26.9 0.0 5.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 AET41660.1 - 0.062 12.7 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold MRG PF05712.8 AET41661.1 - 7.5e-48 162.0 0.0 1.3e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 AET41661.1 - 1.2e-05 24.8 1.1 2.4e-05 23.9 0.8 1.6 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pkinase PF00069.20 AET41662.1 - 1.3e-27 96.6 0.0 3.1e-27 95.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41662.1 - 8.6e-09 34.8 0.0 1.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AET41662.1 - 0.043 13.5 0.0 2.8 7.5 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 AET41663.1 - 0.024 14.5 2.1 0.099 12.5 0.6 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat HECT PF00632.20 AET41664.1 - 1.1e-90 303.9 0.0 1.8e-90 303.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 AET41664.1 - 1.4e-34 117.5 20.5 1.4e-11 44.0 1.4 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 AET41664.1 - 1.4e-16 60.0 0.2 4.4e-16 58.4 0.1 1.8 1 0 0 1 1 1 1 C2 domain TRH PF05438.7 AET41664.1 - 0.053 12.9 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) PUF PF00806.14 AET41665.1 - 4.8e-54 176.9 31.6 1.8e-08 33.4 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ribosomal_S8e PF01201.17 AET41666.1 - 9e-41 139.1 7.6 6.7e-40 136.2 5.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e YebF PF13995.1 AET41666.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 YebF-like protein HPD PF05044.7 AET41666.1 - 0.065 12.9 1.0 0.076 12.6 0.1 1.5 2 0 0 2 2 2 0 Homeo-prospero domain AAA_13 PF13166.1 AET41666.1 - 0.1 11.0 7.8 0.13 10.6 5.4 1.0 1 0 0 1 1 1 0 AAA domain Sas10_Utp3 PF04000.10 AET41667.1 - 1.3e-08 34.9 0.8 4.4e-08 33.2 0.5 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Vfa1 PF08432.5 AET41668.1 - 9.6e-36 123.5 3.4 1.1e-35 123.3 2.4 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Enterotoxin_ST PF02048.11 AET41668.1 - 0.075 13.2 0.3 0.22 11.7 0.2 1.8 1 0 0 1 1 1 0 Heat-stable enterotoxin ST Pkinase PF00069.20 AET41669.1 - 1.9e-55 187.8 0.0 4.6e-55 186.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41669.1 - 3.9e-27 94.9 0.1 1.1e-25 90.1 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AET41669.1 - 0.00024 20.1 0.0 0.13 11.1 0.0 3.3 3 0 0 3 3 3 1 Kinase-like DUF3543 PF12063.3 AET41670.1 - 5.6e-62 209.0 0.5 5.6e-62 209.0 0.3 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 AET41670.1 - 2e-58 197.5 0.0 2e-58 197.5 0.0 3.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AET41670.1 - 1.5e-42 145.5 0.0 1.5e-42 145.5 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase PAT1 PF09770.4 AET41670.1 - 0.092 10.9 111.6 0.19 9.9 77.4 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PLRV_ORF5 PF01690.12 AET41670.1 - 0.72 8.9 53.4 1.3 8.0 37.0 1.5 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein ArfGap PF01412.13 AET41671.1 - 3.6e-29 100.9 1.1 3.6e-29 100.9 0.7 3.0 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.26 AET41671.1 - 0.057 13.2 0.0 0.057 13.2 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain Herpes_UL87 PF03043.9 AET41671.1 - 6.7 4.9 8.4 9.2 4.5 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Mnd1 PF03962.10 AET41672.1 - 1e-49 168.7 10.9 1.2e-49 168.5 7.5 1.0 1 0 0 1 1 1 1 Mnd1 family IncA PF04156.9 AET41672.1 - 0.0023 17.5 8.1 0.0044 16.6 5.6 1.4 1 0 0 1 1 1 1 IncA protein DUF4407 PF14362.1 AET41672.1 - 0.0077 15.2 3.4 0.01 14.8 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) TBPIP PF07106.8 AET41672.1 - 0.0095 15.4 14.8 0.025 14.1 5.3 2.2 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DSX_dimer PF08828.5 AET41672.1 - 0.026 14.0 0.1 0.055 13.0 0.1 1.6 1 0 0 1 1 1 0 Doublesex dimerisation domain NPV_P10 PF05531.7 AET41672.1 - 0.065 13.4 5.1 0.75 10.0 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.8 AET41672.1 - 0.07 13.8 14.8 2.9 8.6 6.2 2.5 1 1 1 2 2 2 0 Occludin homology domain Fib_alpha PF08702.5 AET41672.1 - 0.073 13.2 7.9 0.59 10.2 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.2 AET41672.1 - 0.076 12.3 11.8 0.37 10.0 8.3 1.8 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Flagellin_N PF00669.15 AET41672.1 - 0.14 11.9 1.0 0.96 9.2 0.0 2.2 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region HAUS2 PF15003.1 AET41672.1 - 0.15 11.0 6.5 0.84 8.6 1.5 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 DUF4140 PF13600.1 AET41672.1 - 0.15 12.4 1.7 5.4 7.5 0.0 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3643 PF12356.3 AET41672.1 - 0.16 11.3 1.9 0.22 10.8 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3643) UPF0449 PF15136.1 AET41672.1 - 0.17 12.0 7.6 0.46 10.7 1.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 BLOC1_2 PF10046.4 AET41672.1 - 0.19 11.8 9.6 4 7.6 0.3 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mrr_cat PF04471.7 AET41672.1 - 0.19 11.5 5.0 0.1 12.4 0.9 2.1 1 1 1 2 2 2 0 Restriction endonuclease Nsp1_C PF05064.8 AET41672.1 - 0.2 11.2 11.6 0.099 12.2 1.4 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region GAS PF13851.1 AET41672.1 - 0.23 10.6 18.4 3.6 6.7 12.7 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1955 PF09205.5 AET41672.1 - 0.27 10.7 6.6 0.36 10.3 2.5 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1955) H-kinase_dim PF02895.9 AET41672.1 - 0.46 10.8 2.7 3.7 7.9 1.9 2.3 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Tropomyosin_1 PF12718.2 AET41672.1 - 1 9.1 16.4 10 5.9 11.3 2.1 1 1 0 1 1 1 0 Tropomyosin like COG2 PF06148.6 AET41672.1 - 1.2 9.0 9.4 3.1 7.6 1.0 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 AET41672.1 - 1.6 7.5 16.1 3.7 6.4 3.3 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 AET41672.1 - 4 7.2 15.1 12 5.6 10.5 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 AET41672.1 - 4.3 7.7 11.2 22 5.4 2.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF904 PF06005.7 AET41672.1 - 4.9 7.5 14.7 1e+02 3.2 10.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Seryl_tRNA_N PF02403.17 AET41672.1 - 5.6 7.0 15.0 5.1 7.1 1.6 2.6 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.6 AET41672.1 - 6.7 7.0 12.1 2 8.7 2.6 2.8 2 1 0 2 2 2 0 Rho Binding TMF_DNA_bd PF12329.3 AET41672.1 - 10 6.0 16.3 0.79 9.5 1.7 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-C2H2 PF00096.21 AET41673.1 - 1.6e-11 43.8 16.1 1.3e-06 28.3 0.3 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AET41673.1 - 8.7e-10 38.2 13.0 9.1e-05 22.5 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AET41673.1 - 2.2e-08 34.0 13.3 1.3e-06 28.3 0.8 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AET41673.1 - 7.6e-07 29.1 4.1 0.017 15.2 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AET41673.1 - 2e-06 27.7 3.9 0.025 14.7 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 AET41673.1 - 0.0011 18.9 1.2 0.0022 18.0 0.9 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 AET41673.1 - 0.01 15.7 0.3 0.01 15.7 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 AET41673.1 - 0.071 12.8 5.4 0.33 10.7 0.3 2.5 1 1 1 2 2 2 0 BED zinc finger Med15 PF09606.5 AET41673.1 - 0.22 9.6 27.5 0.33 9.1 19.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C2HC_2 PF13913.1 AET41673.1 - 4 7.2 10.5 2.3 7.9 0.1 2.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_clus PF00172.13 AET41674.1 - 1.3e-08 34.5 9.8 1.3e-08 34.5 6.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AET41674.1 - 5.1e-06 25.5 1.5 1e-05 24.5 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.15 AET41675.1 - 2.6e-119 397.9 0.0 3e-119 397.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Prp19 PF08606.6 AET41676.1 - 3.5e-31 106.7 0.7 6.1e-31 105.9 0.5 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 AET41676.1 - 0.00094 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 U-box domain ENTH PF01417.15 AET41677.1 - 6.2e-29 100.3 0.6 9.4e-29 99.8 0.4 1.3 1 0 0 1 1 1 1 ENTH domain SAP18 PF06487.7 AET41677.1 - 0.026 14.3 0.1 0.17 11.6 0.0 2.2 2 1 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) Phage_int_SAM_1 PF02899.12 AET41677.1 - 0.03 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain ubiquitin PF00240.18 AET41678.1 - 2.9e-69 228.4 7.7 2.7e-34 116.3 0.6 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 AET41678.1 - 2.1e-40 136.2 6.6 1e-19 69.9 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AET41678.1 - 2.9e-13 49.8 2.2 3.9e-05 23.8 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AET41678.1 - 3.3e-11 43.1 0.1 0.00022 20.9 0.0 2.0 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AET41678.1 - 2.5e-07 30.5 0.3 0.033 14.0 0.0 2.7 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AET41678.1 - 5.9e-07 29.5 0.2 0.035 14.2 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 AET41678.1 - 4.2e-05 23.5 0.1 0.49 10.4 0.0 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 AET41678.1 - 0.00084 19.2 0.5 1.3 9.0 0.0 2.2 2 0 0 2 2 2 2 GLUT4 regulating protein TUG Plexin_cytopl PF08337.7 AET41678.1 - 0.0022 16.3 2.7 0.67 8.1 0.2 3.3 3 1 0 3 3 3 2 Plexin cytoplasmic RasGAP domain DUF3221 PF11518.3 AET41678.1 - 0.0068 16.0 0.1 3.8 7.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3221) FlgD_ig PF13860.1 AET41678.1 - 0.0088 15.7 0.5 4.9 6.9 0.0 2.3 2 0 0 2 2 2 2 FlgD Ig-like domain IGR PF09597.5 AET41678.1 - 0.019 14.8 0.0 8.9 6.3 0.0 2.4 2 0 0 2 2 2 0 IGR protein motif Tash_PEST PF07708.6 AET41678.1 - 0.069 13.0 10.5 1.5 8.8 1.2 2.4 2 0 0 2 2 2 0 Tash protein PEST motif GABP-alpha PF11620.3 AET41678.1 - 0.079 12.9 0.8 11 6.0 0.1 2.1 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF3861 PF12977.2 AET41678.1 - 0.08 13.0 0.5 13 5.9 0.0 2.4 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) FERM_N PF09379.5 AET41678.1 - 0.082 12.9 3.6 14 5.8 0.2 3.4 2 2 0 2 2 2 0 FERM N-terminal domain USP7_C2 PF14533.1 AET41678.1 - 0.088 12.2 0.4 11 5.3 0.0 2.0 1 1 0 2 2 2 0 Ubiquitin-specific protease C-terminal CTDII PF01556.13 AET41678.1 - 0.13 12.1 3.8 2.5 8.0 0.2 2.4 1 1 1 2 2 2 0 DnaJ C terminal domain DUF1162 PF06650.7 AET41679.1 - 3.3e-84 282.3 2.8 1.4e-81 273.7 0.0 3.8 3 1 1 4 4 4 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 AET41679.1 - 2.4e-40 136.7 0.0 6.3e-40 135.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Fer2_3 PF13085.1 AET41680.1 - 1.3e-34 118.3 0.1 2.2e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 AET41680.1 - 5.3e-11 42.7 8.0 5.3e-11 42.7 5.5 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AET41680.1 - 2.2e-09 37.1 6.3 2.2e-09 37.1 4.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AET41680.1 - 2.8e-06 27.6 3.6 2.8e-06 27.6 2.5 2.7 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 AET41680.1 - 8.5e-05 22.2 6.0 8.5e-05 22.2 4.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AET41680.1 - 0.0027 17.9 12.3 0.02 15.1 0.3 3.2 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer2 PF00111.22 AET41680.1 - 0.0029 17.3 1.3 0.0029 17.3 0.9 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 AET41680.1 - 0.018 15.4 9.9 0.018 15.4 6.9 2.7 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 AET41680.1 - 0.31 11.6 0.2 0.31 11.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Autophagy_act_C PF03987.10 AET41681.1 - 1.6e-05 24.9 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain V-SNARE_C PF12352.3 AET41682.1 - 8.8e-18 64.1 1.0 8.8e-18 64.1 0.7 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec34 PF04136.10 AET41682.1 - 0.0016 18.1 3.4 0.0022 17.6 1.5 1.8 1 1 0 1 1 1 1 Sec34-like family RseA_N PF03872.8 AET41682.1 - 0.049 13.9 0.9 0.1 12.9 0.6 1.7 1 1 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain DUF148 PF02520.12 AET41682.1 - 0.14 11.9 4.0 0.057 13.2 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 Syntaxin-6_N PF09177.6 AET41682.1 - 9.4 6.7 14.5 0.7 10.3 3.0 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal MIP PF00230.15 AET41683.1 - 7e-58 195.7 1.5 9.6e-58 195.3 1.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein PrgI PF12666.2 AET41683.1 - 1.4 9.0 5.3 0.49 10.5 0.7 2.4 2 1 0 2 2 2 0 PrgI family protein FGGY_C PF02782.11 AET41684.1 - 2.8e-71 239.2 0.4 7.3e-71 237.8 0.2 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AET41684.1 - 1e-48 165.8 0.1 1.4e-40 139.1 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 AET41684.1 - 0.024 13.9 0.2 0.29 10.4 0.1 2.5 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Ribosomal_L7Ae PF01248.21 AET41685.1 - 2.5e-23 81.3 0.4 4.1e-23 80.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AET41685.1 - 0.0031 17.3 0.1 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 RRM_1 PF00076.17 AET41686.1 - 1.2e-16 60.0 4.2 1.2e-09 37.6 0.3 3.4 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AET41686.1 - 4.7e-12 45.7 0.2 7.2e-05 22.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AET41686.1 - 0.067 13.0 0.3 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 AET41687.1 - 1e-57 194.2 0.0 4.5e-34 117.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AET41687.1 - 7.5e-51 173.1 32.7 3.3e-28 98.8 9.6 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 AET41687.1 - 6.9e-11 42.6 1.4 2.4e-05 24.4 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AET41687.1 - 2.8e-10 40.8 3.0 2.2e-05 24.8 0.5 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AET41687.1 - 8.5e-09 34.9 4.6 0.00055 19.2 0.5 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AET41687.1 - 3.3e-07 29.7 1.4 0.0011 18.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AET41687.1 - 3.4e-06 26.3 0.1 0.088 11.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 AET41687.1 - 3.9e-05 22.6 0.1 0.028 13.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 AET41687.1 - 6e-05 23.8 0.0 0.26 12.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 AET41687.1 - 6.3e-05 22.8 0.0 0.02 14.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 AET41687.1 - 0.00012 22.5 0.1 0.34 11.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 AET41687.1 - 0.00013 21.9 0.1 0.58 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 AET41687.1 - 0.00041 19.5 0.4 0.76 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AET41687.1 - 0.00077 19.6 0.1 3 7.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AET41687.1 - 0.00082 18.8 0.0 0.39 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 AET41687.1 - 0.0011 18.7 0.9 1.3 8.7 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 AET41687.1 - 0.0012 17.9 0.1 1.4 7.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 AET41687.1 - 0.0046 16.4 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.1 AET41687.1 - 0.0069 15.9 0.3 2.8 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 AET41687.1 - 0.007 16.2 1.7 0.44 10.3 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 AET41687.1 - 0.0071 16.0 0.0 0.072 12.7 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 AET41687.1 - 0.0082 16.0 0.2 3.8 7.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 AET41687.1 - 0.012 15.2 0.0 19 4.7 0.0 3.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 AET41687.1 - 0.015 15.1 0.4 4.1 7.2 0.0 2.9 2 1 1 3 3 2 0 AAA domain AAA_18 PF13238.1 AET41687.1 - 0.015 15.6 0.3 8.6 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 AET41687.1 - 0.019 14.3 0.6 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 AET41687.1 - 0.023 14.1 0.1 1.2 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 AET41687.1 - 0.044 13.3 0.0 10 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 AET41687.1 - 0.056 12.0 0.0 6 5.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 AET41687.1 - 0.063 13.0 0.4 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Dynamin family ResIII PF04851.10 AET41687.1 - 0.075 12.8 0.0 5.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Adeno_IVa2 PF02456.10 AET41687.1 - 0.11 11.1 0.1 3.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.17 AET41687.1 - 0.17 12.1 0.0 20 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 AET41687.1 - 0.19 11.3 0.6 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AA_permease_2 PF13520.1 AET41688.1 - 1.8e-59 201.3 41.2 2.3e-59 201.0 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AET41688.1 - 2.3e-16 59.2 37.3 2.8e-16 58.9 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0093 PF03653.8 AET41688.1 - 0.55 10.1 5.4 5.9 6.8 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) Dynamitin PF04912.9 AET41690.1 - 0.0084 14.9 0.5 2.9 6.5 0.1 2.4 3 0 0 3 3 3 2 Dynamitin DUF2497 PF10691.4 AET41690.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) Cofilin_ADF PF00241.15 AET41691.1 - 7.6e-42 142.1 0.3 8.5e-42 142.0 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HTH_Tnp_Tc5 PF03221.11 AET41692.1 - 2.6e-13 49.5 1.3 7.1e-13 48.1 0.1 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 AET41692.1 - 0.075 12.4 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Phosphoesterase PF04185.9 AET41693.1 - 2.6e-37 128.9 3.2 1.3e-35 123.3 2.1 2.7 1 1 1 2 2 2 2 Phosphoesterase family Cu-oxidase PF00394.17 AET41694.1 - 8.7e-35 119.9 0.3 2.3e-32 112.0 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AET41694.1 - 7.2e-33 113.0 0.8 7.2e-33 113.0 0.6 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 AET41694.1 - 4.5e-31 107.0 0.3 4.5e-31 107.0 0.2 2.6 4 0 0 4 4 4 1 Multicopper oxidase